LOCUS       DARYYD010000001        70404 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.001, whole genome shotgun sequence.
ACCESSION   DARYYD010000001 DARYYD010000000
VERSION     DARYYD010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 70404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 70404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..70404
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.001"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..351
                     /locus_tag="TV188_000001"
     CDS             <1..351
                     /locus_tag="TV188_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1533408.1"
                     /translation="RGEQGPKGDRGEQGPKGDRGEQGPKGERGEQGPKGDRGEQGPKK
                     EPEKDTKPSVPKAPDNMAAPKAPEKKNPKAPAPKSAPKASLPSTGDTSQSFVAAALGF
                     IASAGLLVFKRKKN"
     gene            877..1767
                     /gene="rapZ"
                     /locus_tag="TV188_000002"
     CDS             877..1767
                     /gene="rapZ"
                     /locus_tag="TV188_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEL1533409.1"
                     /translation="MSDKQINLVIVTGMSGAGKTVAIQSFEDLGYFTVDNMPPALVPK
                     FLELLERTNETQKVALVVDMRSRRFFKEINSILDHIELNANLKLRILFLDATDSELVS
                     RYKETRRSHPLAADGRVLDGIRRERELLVPLKSMSQHVVNTTDLTPRQLRKVISDQFS
                     SESDQASFRIEVMSFGFKYGLPLDADLVFDVRFLPNPYYQVALREQTGLDQAVFDYVM
                     THQESEAFYNHLLGLIVPILPAYQKEGKSVLTIAIGCTGGQHRSVAFAHRLAQDLTAD
                     WPLHESHRDINRRKETVNRS"
     gene            1764..2741
                     /locus_tag="TV188_000003"
     CDS             1764..2741
                     /locus_tag="TV188_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEL1533410.1"
                     /translation="MRNPKITVIGGGTGIPVILKSLRKEAVDITAVVTVADDGGSSGK
                     LRNAMQLTPPGDLRNVLLAMSDMPKFYERVFQYRFNEADGALAGHPLGNLIIAGISEM
                     QGSTYNAIQILTKFFHITGKIFPSSEQPLTLHAVFKDGHEVSGESSIASYQGMIDHVY
                     VTNTYNDDLPKASRKVVEAILQSDMIVLGPGSLFTSILPNLVIPEIKEALRVTKAEVV
                     YICNIMTQYGETEQFSDADHVAVLNQHLGRDLIDTVLVNVEQVPKSYMNSNQFDEYLV
                     QVEHDFAGLCKTAKRIISSNFLRLENGGAFHDGHLVVEELMNLVRITKL"
     gene            2738..3649
                     /gene="whiA"
                     /locus_tag="TV188_000004"
     CDS             2738..3649
                     /gene="whiA"
                     /locus_tag="TV188_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEL1533411.1"
                     /translation="MSFTTTVKEELIHLSASDQTELSAIIKLAGSLGLANQSLNLSIT
                     TENAKIARYIYALIEDTYHIIPEIRYHQKTNLKKNRVYTVYLDKQVDKLLADLKLADS
                     FFGIETGIEQQVMSDDDAGRAYLKGAFLAAGTVRDPESGKYQLEIYSVYLDHAQDLAQ
                     LMHKFMLDAKVIERKNGAVTYLQKAEDIMDFLIIIGAMSCKEEFEAVKLLREARNDIN
                     RANNAETANIAKTITASMRTINNIIKIMDTIGLDSLPVELQQIAQMRVANPDYSLQQI
                     ADSLDFAITKSGVNHRLRKINKLAEDL"
     gene            4009..5406
                     /locus_tag="TV188_000005"
     CDS             4009..5406
                     /locus_tag="TV188_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C69 family dipeptidase"
                     /protein_id="HEL1533412.1"
                     /translation="MSCTTILVGKKATYDGSTIVARTEDSQNGEFTPKKMTVVRPKDQ
                     PRHYQSVLSSFSMELPDQPMAYTSVPDALGKDGIWGEAGVNTLNVAMSATETITSNAR
                     VLGADPLVSSGIGEEDMLTLVLPYIRSAREGVLRLGAILEAYGTYEANGVAFSDEHEI
                     WWLETIGGHHWIARRVPDDAYVTNPNQFGLDHFEFNNPEEYLCSKDLKDFIAKYHLDL
                     TYSNEHFNPRYAFGSQRDKDRHYNTPRAWIMQQYFNPEFLQDPRSFELPWCQRPDRKV
                     TIEDVKYVLSNHYQDTPYDPYGPEGTPTSRKSFRPIGINRTSQTAILHIRPNKPKEIA
                     AIQWMAYGSMPFNTIVPLFTQVKTIPDYFANTVENVSTDNFYWTNRLIAALADPHFKH
                     HEADLEDYLEKTMAKGHAMLHAVEAALVKGQPVDLEEANQGMSDDIQADTQALLNKIL
                     FDASNLMTNRFSLSD"
     gene            5646..7196
                     /locus_tag="TV188_000006"
     CDS             5646..7196
                     /locus_tag="TV188_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HEL1533413.1"
                     /translation="MKKKYLLMMSVLGVFFAGQISQAKQVLADSKVKIVTTFYPVYEF
                     TKGVVGGEGNVSMLMKAGTEPHDFEPSTKDIKKIQDADAFVYMDDNMETWVPDMKKSL
                     TSKKVTVIKGTGDMLLVAGSGHSHEHDHDDADKKHDHDHDEEGHSHAFDPHVWLSPYR
                     SITVVETIRDGLSKAYPDKADHFKSNAAAYIEKLKELDKEYSDAFSAAKQKSFVTQHA
                     AFGYMALDYGLNQISINGVTPDTEPSAKRIAELSKYVKKYDINYIYFEENASSKVAKT
                     LAKEAGVKSAVLSPLEGLTEKDMKAGKDYFTVMRENLKTLRLTTDVEGKEILPEEDTT
                     KTVYNGYFKDKQVKDRKLSDWSGNWQSVYPFLQDGTLDQVWDYKAKKSKGKMTAAEYK
                     DYYTTGYQTDVSHIKINGKKNTMTFVRNGENKTFTYKYVGKKILTYPKGNRGVRFMFE
                     AKEPDAGEFKYVQFSDHAIAPGKAEHFHLYWGGDSQEKLHKELEHWPTYYDADLSGRA
                     VAQEINAH"
     gene            7467..8195
                     /locus_tag="TV188_000007"
     CDS             7467..8195
                     /locus_tag="TV188_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1533414.1"
                     /translation="MIKEQPLYLQIVDVLEVKIRNTMSANDKLLSERELSDLFGVSRI
                     TIRLALKELELRGLIYKQQGKGTYVSGIKEPATDLSSAYSFTEEMKKQGRKPQTVILS
                     FEKIKTTAYLSGMLDLDVDTDVFELERLRIADGKPLMFERTYIPERGFEAITIDLLEK
                     KPLYDVFAEDFQEAIRLADEEFYASIALDYEAKLLGIKKGDPVLHIMRKTYNEKNRLI
                     EFTFSIARADQFRYRIQHHPNKKI"
     gene            8207..9382
                     /locus_tag="TV188_000008"
     CDS             8207..9382
                     /locus_tag="TV188_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEL1533415.1"
                     /translation="MFTKTQAELELLGAAITTREIKQQPELWSEVFESFLKQKKDLLA
                     FFDRIIESANRNKVKIIFTGAGTSEYIGNTICHYLEMTGDRENYLYYSIASTDLVAAP
                     SQYLFEEDTVVLVSFARSGNSPESVAAVSLVNQLVSNPYHLVITCAKEGALAQNAKKD
                     KRSYLFLLPEASNDAGFAMTGSFSCMMLAALLIFDQAHSLEEKKCYLDQIVGMVAAII
                     QQEADLQKLVSLEFQRLVYLGSGALAGLTQEAQLKILELTAGKIATVYDSSMGFRHGP
                     KSFIDDQTLVIGFVSNDPYTRRYDLDVLEEIREDAIAVDTVALQQQGGEGFSGHCFGL
                     DSSMLLPDAYLAFPLVFIAQTLALLSSIKVNNLPDTPSATGTVNRVVQGVKIYHYFK"
     gene            9392..10387
                     /gene="lacD"
                     /locus_tag="TV188_000009"
     CDS             9392..10387
                     /gene="lacD"
                     /locus_tag="TV188_000009"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEL1533416.1"
                     /translation="MYHLSKAKYRLLEKVSRKGIISALAFDQRGVLKRMMAAHQDTEP
                     TPWQIEALKALVSEELTPYASSILLDPEYGLPATKVRDEKSGLLLAYEQTGYDTTTTS
                     RLPDCLVDWSVKRLKEAGADAVKFLLYYDVDGDERINQQKQAYIERIGSECQAEEIPF
                     FLELLTYDEAITDNQSVAFAKLKAHKVNEAMKVFSTERFGVDVLKVEVPVNMAYVEGF
                     AEGEVVYSKEEAMQAFRDQEAASHLPYIYLSAGVSASLFQETLVFAAEAGARFNGVLC
                     GRATWSGAVAVYMSEGEEAARQWLRTEGFENIDRLNQVLEKTASPWTTKLTLDEA"
     gene            complement(10429..11148)
                     /locus_tag="TV188_000010"
     CDS             complement(10429..11148)
                     /locus_tag="TV188_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1533417.1"
                     /translation="MTIKYPKYRLIKEELQNQILNGHYHTGDKFYTEAELIKRFHVSS
                     ITIIRALKELEKEGFIRRRQGLGTFITRTRKEQLVQFSYLGTFKDQKEEVTVLSVVKG
                     NDPYYLNLLKLHKTEFYYTISRTRTINQQPYLYQLSYIPHDYLLCPERDLADYQSLYK
                     RFFLDFHIQMRSQSFTQQTQLTDHMPKDVATFLNMIDNTPCVLQTKLTRSTDNGRILE
                     YTESYKHWQFFKYALSSSDYQ"
     gene            11288..13051
                     /locus_tag="TV188_000011"
     CDS             11288..13051
                     /locus_tag="TV188_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1533418.1"
                     /translation="MKQFCIKEQFYLDGKPFKILSGAIHYFRIAPDSWSRVLYQLKAL
                     GFNTVETYIPWNMHEPRKGQFTFEGIADVEAFLDLAQECGLYAIVRPSPYICAEWEFG
                     GLPAWLLTENCRLRSSDEVFLKHVSDYYDVLLPKLVKRQLDNGGNILMFQLENEYGSY
                     GEEKAYLRKLKELMLAKGISAPLFTSDGPWPATLASGSLIDDDVFVTGNFGSNASKQF
                     ASMQDFFQAHQKQWPLMCMEFWLGWFNRWNEPIIRRDSKEAVDAIMEAIELGSINLYM
                     FCGGTNFGFMNGSSARLQKDLPQITSYDYDALLDEAGNPTKKYTLLQERLKECYPQLS
                     FAEPMISSTMALESIKLSARVSLFKTIKNVSAIKKSFYPCNMEELDQPTGYLLYRTHL
                     ARHSKEERLRVIDARDRIQLFLDEKHVKTQYQEEIGQDILIHQEGETTQLDILVENMG
                     RVSYGYKLTAPSQQKGLGRGLMADLHFVGDWEHFPLDFQELDWIDFSAGWTDEVPGFY
                     AYDFDCQQPADTYLDLSQFGKGIALVNGVNLGRFWKVGPTLSLYIPKGLLKQGQNRLL
                     IFETEGQFSESIRLTKEPIYK"
     gene            13069..13554
                     /locus_tag="TV188_000012"
     CDS             13069..13554
                     /locus_tag="TV188_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1533419.1"
                     /translation="MTIVAARIDGRLIHGQVANLWTTKLNISRIMVVDNEVISNDLEK
                     TALKLATPSGVKLSILSVEKAANNILEGRYDSQRLLIVARKPDSFLELIQKGVAISEL
                     NVGNMSQTPETRPVTRSINVVDEDIEAFKAISAKGCHLIAQMVPNDAPADFMPLLDKV
                     D"
     gene            13600..14481
                     /locus_tag="TV188_000013"
     CDS             13600..14481
                     /locus_tag="TV188_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1533420.1"
                     /translation="MIQWWQILLLTLYSAYQILDELTIVSSAGSPVFAGFISGIIMGD
                     VQTGLWIGGSLQLMVLGVGTFGGASRIDATSGAVIATAFSVAQGIEPELAISTIAVPV
                     AALLVYTDILGRFSTTFFAHRIDRHVENFNYRGIERDYLMGAVPWALSRALPVFLAVS
                     LGGGAVDTVVKFIDHYEWLANGLTLAGKMLPGLGFAILLHYLPVKRNLHYLALGFGLT
                     AMLTTIYTNLQVAGGALAGVAKDFNAAPFKGLPMIGIAIIGLSLATLHYKNGQQAPVA
                     EQKPGVSESGEIEDDEI"
     gene            14468..15286
                     /locus_tag="TV188_000014"
     CDS             14468..15286
                     /locus_tag="TV188_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HEL1533421.1"
                     /translation="MTKSNYKLTKQDFNQINKRSLFTFQWGWNYERMQGSSYLYMILP
                     QLRKIYGDGTPELKEMMKTHTQFFNTSNFFHTIITGIDLALEENEGLASKDAVNGIKT
                     GLMGPFAPIGDSVFGSLVPAIMGSIAAGLAKEGVWSGITGVLMWVCTQMIINVFRWKQ
                     LEIAYKEGTKLVTTMRDKLTAVVDAASVMGVFMVGALIATMINFQFTAAPKIGEKVIN
                     IQDLIDTIFPRLVPALFTGGIFWLLGRKGMSPTKAIVVIILFALVMSYFNILGV"
     gene            15290..15694
                     /locus_tag="TV188_000015"
     CDS             15290..15694
                     /locus_tag="TV188_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HEL1533422.1"
                     /translation="MAQTLILISHGAFCRELKQSTEMIMGPQDNILTAELQPNEGADD
                     FKEKLLRLIAGLDDVLVFADLMGGTPCNVASRLLMEGHQFELYAGMNMPMVIGFINAC
                     LIGEAFDFKAFACDNIHHVNTIISALADDDDD"
     gene            complement(15798..16058)
                     /locus_tag="TV188_000016"
     CDS             complement(15798..16058)
                     /locus_tag="TV188_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEL1533423.1"
                     /translation="MRKDIHPDYRPVVFLDTTTGYKFLSGSTKTSKETIEFEGETYPL
                     VRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAK"
     gene            complement(16183..17115)
                     /locus_tag="TV188_000017"
     CDS             complement(16183..17115)
                     /locus_tag="TV188_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEL1533424.1"
                     /translation="MTTFQTILEHIKHYQTIIIHRHQNPDPDALGSQAGLKEIIRHNF
                     PDKKVLITGFDEPSLAWISLMDQVSDDDYKEALVIVTDTANRPRIDDERYTMGACLIK
                     IDHHPNDDVYGDLSYVDTKTSSASEIIAEFAFSQGLALTDEAARLLYTGIVGDTGRFL
                     YASTSSKTLAIASQLRNYAFDFAAISRQMDSFPLKIAKLQGYVFEQLDIDDSGAARLL
                     LSQEVLNSFGISLAESSAIVSAPGKIDVVQAWVIFVELPDGQYRVRMRSKEKVINGIA
                     KRHQGGGHPLASGATSSGLEENEQIYQELIDLLT"
     gene            complement(17125..17553)
                     /locus_tag="TV188_000018"
     CDS             complement(17125..17553)
                     /locus_tag="TV188_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1533425.1"
                     /translation="MWVVKAFDQLTKDELFAIYKERVAVFVVEQQCPYPDIDDLDQKA
                     IHLFKQVDSELRAYCRLIPTDNSIKLGRVLVAQNARRTGLGRDLVHQALAYCQQHFPK
                     LPVYAQAQAYLEPFYSSFGFKAVSEIYLEDNIPHIDMIKN"
     gene            17811..18836
                     /locus_tag="TV188_000019"
     CDS             17811..18836
                     /locus_tag="TV188_000019"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HEL1533426.1"
                     /translation="METKDLKKLAKAELHCHLDGSLSLDTIRQLAALAQVDVPQDDSE
                     LKQLVTAPETCESLMDYLKTFDVIRPLLQTPQALTLAAYDVVKQAALENVIYIEIRFA
                     PELSMDQGLTATQVVEAVLKGLEQGQKEFGIVAKAIVCGMRQSSLDISREIFANVLEW
                     ANKGLVGFDFAGNELDFPPAVLADLIKETQAYGLPFTLHAGECGCPNYIVDAIDLGIK
                     RLGHVTAIHNQKDLLAKFIANDVTAELCFTSNLQTKAARTVEDFPYMQLRQAGAKLSI
                     NTDNRTVSDTNLTKEYELFVKHFETSVTDFLEHNRDAIKASFASPAEKEALLDRLEKA
                     YQSYIKK"
     gene            18897..19343
                     /locus_tag="TV188_000020"
     CDS             18897..19343
                     /locus_tag="TV188_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEL1533427.1"
                     /translation="MALAKIVYASMTGNTEEIADIVANKLQELGHDVEVDECTTVDAS
                     ELEAADMAIVATYTYGDGDLPDEIVDFYEDLQDLDLSGKIYGVVGSGDTFYDYFCKSV
                     DDFDEQLAATGATKGADSVKVDLAAEEEDIARLESFAEQMSQALEA"
     gene            19672..19965
                     /locus_tag="TV188_000021"
     CDS             19672..19965
                     /locus_tag="TV188_000021"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEL1533428.1"
                     /translation="MGLETIRQDINAVDRQLIALLEKRMVLADQVAAYKQVHDVPVLD
                     QEREAEVLRSVSQQIRHKAFEPAILELFKTIMAVSRRYQAEQIAVGSNDDEAY"
     gene            19946..21177
                     /locus_tag="TV188_000022"
                     /pseudo
     CDS             19946..21177
                     /locus_tag="TV188_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622696.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            21323..21670
                     /gene="rplS"
                     /locus_tag="TV188_000023"
     CDS             21323..21670
                     /gene="rplS"
                     /locus_tag="TV188_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEL1533429.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGSRERIQIFE
                     GVVISRKSQGISEMYTVRKISSGIGVERTFPIHTPRVEKIEVVRHGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            22185..22256
                     /locus_tag="TV188_000024"
     tRNA            22185..22256
                     /locus_tag="TV188_000024"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22218..22220,aa:Arg,seq:cct)
     gene            complement(22380..23183)
                     /locus_tag="TV188_000025"
     CDS             complement(22380..23183)
                     /locus_tag="TV188_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1533430.1"
                     /translation="MSKSRRRNWKSLTIVLLTILTIFTANSVQSARKLRTFPDTTEIS
                     LGTKATEIPGILPFTGKYQIALGDLDHLQRATYAHIQLKDQDEPTLKRKALRFNPPGW
                     HNYQVINSRGKKTWLMDRGHLVGYQFSGLNDEPKNLVTMTKYLNTGFSDKNPLGMLYY
                     ENRLDNWLAIHPNFWLDYKVTPIYQNDELVPRQVVLQYVGIDQNGELLQIKLGGNKES
                     VDHYGITSVVLDNVSPLAALDYRTGMLLDENQHTEEGNNLATEELDEAA"
     gene            23811..24026
                     /locus_tag="TV188_000026"
     CDS             23811..24026
                     /locus_tag="TV188_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1533431.1"
                     /translation="MAYRLRNRLKELRARDGINQTQMAALAGVSRQTISLIERNEYTP
                     SIIIAMKIAKVFNEPIEQVFSLVEGER"
     gene            24023..24799
                     /locus_tag="TV188_000027"
     CDS             24023..24799
                     /locus_tag="TV188_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEL1533432.1"
                     /translation="MKAFMTEKDSTLVRILKSLLLGSGIGLVLGGLVGFGLARFNILE
                     NGFPISEEDTITGIKWGMRPLVIVLMLLSIYDIYQVVKEYARYVKLSDDETEELYRYI
                     NLKHAYALGFSAMAMVLNIVVFSLGYRVPIANNASYLGLTFPIYEALMLVVISVLHAY
                     ILKVYTRIRGVKMTLAPTLKELKQNILQQDEAELQANYQMSFEVVMGLSGFILPGIYV
                     ILLLLSMIFQRVELTGLIITASIHLYILVKSFKSAHDFYR"
     gene            complement(24868..26124)
                     /locus_tag="TV188_000028"
     CDS             complement(24868..26124)
                     /locus_tag="TV188_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEL1533433.1"
                     /translation="MITRLITFLTWTGQLVVAGVIAGVVAYVLTQAIHFIQAISFGYQ
                     SGSFSTMIATVAPERRFLSLLLAGAIAGLGWQLLAKKAKPIQPIQQTLSQQKDFSPWT
                     QFCHGWLQLITVSMGAPVGREGASREVAVALTAACNKAINASAAEQGLLLACASGAAL
                     GAVYQAPLATIVFIMEAIVKKCSVKHIYAAAITAFTAVQSVLVLSGHQDIQYLILPQA
                     WQLTTVLWAIIASPILAFLAFCYQQLLQNAPKAKPKSRWFIPRVLGAFGFSACLSLYF
                     PEILGNGKAGLLLLLHHDVSLSYTASLLLSKAAAVYAVFASGAKGGKIAPSMMLGGAS
                     GLLLASLSNQLGYLSVPLPLAIVIGATLFLGIINQIPLTAPLFLIEITGQPLISLVPL
                     AIVGLTSYLSQQLFQKSLFFNKHKKL"
     gene            complement(26210..27169)
                     /gene="nrdF"
                     /locus_tag="TV188_000029"
     CDS             complement(26210..27169)
                     /gene="nrdF"
                     /locus_tag="TV188_000029"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1533434.1"
                     /translation="MTTYYEAINWNEIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RRLSAVEKDLVGKVFGGLTLLDTMQSESGVEAIRKDVRTPHEEAVLNNIQFMESVHAK
                     SYSSIFSTLNTKKEIEDIFEWTNNNVFLQNKAKIINDIYENGSALQKKVASTYLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSESEQESLR
                     DWMYDLLYQLYENEEQYTKTLYDEVGWTEEVMTFLRYNANKALMNLGQDPLFPDTAND
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGTVEAMTDDDYNYGL"
     gene            complement(27314..29473)
                     /gene="nrdE"
                     /locus_tag="TV188_000030"
     CDS             complement(27314..29473)
                     /gene="nrdE"
                     /locus_tag="TV188_000030"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1533435.1"
                     /translation="MSLKDLGDISYFRLNNEINRPVDGSIPLHKDKEALEAFFTENVI
                     PNTMSFSSINEKIAYLVDNDYIESAFIQNYSPEFISHLAKSIQAEGFRFKSFMAAYKF
                     YQQYALKTNDGNFYLESIEDRVMFNALYFADGDETLAKDLAIEMINQRYQPATPSFLN
                     AGRSRRGELVSCFLLQVTDDMNAIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGY
                     AGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLSVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGITVPDKFYELARHNADMYLFSPYSVEREYGLPFNYIDITSMYDELVANPNI
                     TKTKIKARDLETEISKLQQESGYPYVINIDTANRSNPIDGKIIMSNLCSEILQVQTPS
                     LINDAQEFVKMGTDISCNLGSTNILNMMTSPDFGRSIRAMTRALTFVTDSSNIEAVPT
                     VKNGNSQAHTFGLGAMGLHSYLAQHHIEYGSPESIEFTDIYFMLMNYWTLVESNQIAR
                     ERQTTFVGFEKSTYASGAYFDQYITGECVPKSELVKSLFKDHFIPQAADWKALRQAIM
                     TDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTI
                     PYYTSAYDMDMRKVIDVYAAATKHVDQGLSLTLFLRSELPKELYEWKTESKQTTRDLS
                     ILRHYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI"
     gene            complement(29494..29712)
                     /gene="nrdH"
                     /locus_tag="TV188_000031"
     CDS             complement(29494..29712)
                     /gene="nrdH"
                     /locus_tag="TV188_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEL1533436.1"
                     /translation="MITVYSKHNCMQCKMTKKFLEQHGAAFQEINIDEHPEKVDYVKS
                     LGFTAAPVIETEQIVFSGFQPAKLKDII"
     gene            30134..30397
                     /locus_tag="TV188_000032"
     CDS             30134..30397
                     /locus_tag="TV188_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEL1533437.1"
                     /translation="MASKDFHIVAETGIHARPATLLIQTASKFASDITLDYKGKAVNL
                     KSIMGVMSLGVGQGADVTITAEGADADDAIAAIEETMTKEGLA"
     gene            30402..32135
                     /gene="ptsP"
                     /locus_tag="TV188_000033"
     CDS             30402..32135
                     /gene="ptsP"
                     /locus_tag="TV188_000033"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEL1533438.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DVALQASQDELSVIREKAVESLGEEAAAVFDAHLMVLADPEMISQIKETIRAKQTNAE
                     TGLKEVTDMFITIFEGMEDNPYMQERAADIRDVAKRVLAHLLGVKLPNPATIDEEAIV
                     IAHDLTPSDTAQLNKQFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNDITKRVKDGD
                     LIAVNGITGEVIIDPSEEQILAFKEAGEAYAKQKAEWALLKDAQTVTADGKYFELAAN
                     IGTPKDVEGVNDNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDLPKEMNPFLGFRALRISISETGNAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKVVFEEEKASLLSEGVAVADDIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDSAKMAEYAHRALTECSTAEEV
                     LELAKEYITEA"
     gene            32337..33764
                     /locus_tag="TV188_000034"
     CDS             32337..33764
                     /locus_tag="TV188_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1533439.1"
                     /translation="MAKQYKNLVNGEWKLSENEIKIYAPATGEELGSVPAMSREEVDQ
                     VYASARAALADWRALSYVERTAYLHKAADILVRDAEKIGAVLSKEVAKGYKAAVSEVI
                     RTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAIVRREPVGLVLAISPFNYPINLA
                     GSKIAPALIAGNVVVLKPPTQGSISGLLLAEVFAEAGLPAGVFNTITGRGSVIGDYIV
                     EHEAVNFINFTGSTPIGERIGKLAGMRPIMLELGGKDSAIVLEDADIALAAKNIVAGA
                     FGYSGQRCTAVKRVLVMESVADQLVAEIKGLVEKLLIGMPEDNADITPLIDTKAADFV
                     EGLVNDAADKGAQALTEIKRDGNLICPILFDRVTTDMRLAWEEPFGPVLPVIRVSSVE
                     EAISISNQSEYGLQASIFTTNFPQAFAIAEKLEVGTVHINNKTQRGTDNFPFLGAKKS
                     GAGVQGVKYSIEAMTSLKSVVFDIQ"
     gene            34417..35631
                     /locus_tag="TV188_000035"
     CDS             34417..35631
                     /locus_tag="TV188_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1533440.1"
                     /translation="MLPKRKLIDQRLDYAIIFPVFCLLIFGLVSVYVAASHDFPQSLA
                     TVMLQQVLWILLGAVIAFTLMFFSTEILWKLTPVFYLLGVLLMVLPLIFFSPRLVAAT
                     GAKNWITIGSTTLFQPSEFMKISYILAMSWLTVWFKRKQERSRFLDDWKLLGLYLVLT
                     LPVMVLLALQKDLGTAMVFLAILAGIILISGISWWLILPALVLVFLLVSAFFFVFLLP
                     EGKEFLLKMGMDTYQLNRISAWLTPFDFSDTIAYQQTQSMISIGSGGFFGKGFNQLEL
                     SVPVRESDMIFTVIAENFGFLGAASLLILYLILIYRMLRVTFASNNLFYTYISTGFIM
                     MILFHIFENIGAAVGLLPLTGIPLPFISQGGSSLISNLIGVGLILSMNYQHVLAHEKQ
                     SEHELSRSSRYV"
     gene            35727..36296
                     /locus_tag="TV188_000036"
     CDS             35727..36296
                     /locus_tag="TV188_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1533441.1"
                     /translation="MKVMNYHDYIWDLGGTLLDNYEISTQAFIETLHFFKLSASHDAV
                     YQRLKKSTATAIQVFAPNEPQFLQYYKANEAKKLANPIWCLGAKDILKRIVASGSRNF
                     LISHRDHQVNDLLEQAGLLGYFTEVVTASNGFARKPNPESLLYLKEKYLISKGLVIGD
                     RRLDIEAGQAAGFDTLLVDGRKNLLEIVD"
     gene            36297..38249
                     /gene="gyrB"
                     /locus_tag="TV188_000037"
     CDS             36297..38249
                     /gene="gyrB"
                     /locus_tag="TV188_000037"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEL1533442.1"
                     /translation="MVEENKQLEDKAQEYDASQIQVLEGLEAVRMRPGMYIGSTAKEG
                     LHHLVWEIVDNSIDEALAGFASHIQVFIEADNSITVIDDGRGIPVDIQAKTGRPAVET
                     VFTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVRVYKNGHIHYQEFRRGAVV
                     DDLAIIGTTDVTGTTVHFTPDPEIFTETTEFDYQVLAKRIQELAFLNRGLKISITDKR
                     AGLEREEHFHYEGGIGSYVAFLNDKKDVIFDTPIYSDGELEGITVEVAMQYTTGYHET
                     VMSFANNIHTHEGGTHEQGFRTALTRVINDYAKKAKILKENEDNLTGEDVREGLTAVI
                     SVKHPNPQFEGQTKTKLGNSEVVKITNRLFSEALQRFLLENPQVARKIVEKGILASKA
                     RIAAKRAREVTRKKSGLEISNLPGKLADCSSNDASQNELFIVEGDSAGGSAKSGRNRE
                     FQAILPIRGKILNVEKATMDKILANEEIRSLFTAMGTGFGAEFDVSRARYQKLVIMTD
                     ADVDGAHIRTLLLTLIYRFMRPVLEAGYVYIAQPPIYGVKVGSEIKEYIQPGVNQEEE
                     LKAALERHSTGRSRPTIQRYKGLGEMDDHQLWETTMDPDNRLMARVTVDDAAEADRIF
                     DMLMGDRVEPRREFIEENAVYSTLDI"
     gene            38398..40122
                     /gene="ezrA"
                     /locus_tag="TV188_000038"
     CDS             38398..40122
                     /gene="ezrA"
                     /locus_tag="TV188_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEL1533443.1"
                     /translation="MSSGIILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQAL
                     FGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFN
                     FIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
                     ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITE
                     QIPAIVAKLEDDFPDQLDDLETGYRRLLEENYHFPEKNIEARFQEIRESIRANSSELV
                     TLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKH
                     EIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSI
                     KTLASVESGQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFL
                     STFFTTSSQLEALMDELSRGRINIEAVSRLSEVATAAIANLEELTYQVVQHATLTEQL
                     LQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERFVNSYE
                     KTRERIRF"
     gene            40493..40774
                     /locus_tag="TV188_000039"
     CDS             40493..40774
                     /locus_tag="TV188_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533444.1"
                     /translation="MKITKALCVAGAVAVLALAPISSSPAPTQTVFAATRGTEEYCHN
                     GWCSFLDEHGEWNTKREGESNSPLQRGSWWDWISYWSGYIWYSVYNWFR"
     gene            complement(40959..41414)
                     /locus_tag="TV188_000040"
     CDS             complement(40959..41414)
                     /locus_tag="TV188_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1694 domain-containing protein"
                     /protein_id="HEL1533445.1"
                     /translation="MDSLDTRLLKGASGENRFDPDQQRYYLGTYAERIVLALPLTEVD
                     HEKAKGYITAQLPHLKEAYFPLSFKLSSEFGSAYQMYYMKLAQQNALSATIVDEKGAV
                     SPFALIIHSDHAITKEETNLKAILDKPSDNKPAEQTKTKGKSLWQRLFH"
     gene            41645..42952
                     /gene="eno"
                     /locus_tag="TV188_000041"
     CDS             41645..42952
                     /gene="eno"
                     /locus_tag="TV188_000041"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEL1533446.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKARGLVTAVGDEGGFAPKFEGTEDG
                     VETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQI
                     DYLEELVNKYPIITIEDGMDENDWEGWKALTERLGKRVQLVGDDFFVTNTEYLARGIK
                     EGAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAG
                     QIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK"
     gene            complement(43088..43324)
                     /locus_tag="TV188_000042"
                     /pseudo
     CDS             complement(43088..43324)
                     /locus_tag="TV188_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400084.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            43533..43754
                     /locus_tag="TV188_000043"
     CDS             43533..43754
                     /locus_tag="TV188_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation repressor RelB"
                     /protein_id="HEL1533447.1"
                     /translation="MSTVTIRLNQEEEIFFKSYAQLTGQSLSSLFKKALERDIEDEYD
                     LKIYHQAYAEYKADPETISHADFKKELGL"
     gene            43756..44016
                     /locus_tag="TV188_000044"
     CDS             43756..44016
                     /locus_tag="TV188_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1533448.1"
                     /translation="MYRIEYSKKAQKQIKKVDKQIQRLLFAWIDKYLEGTDNPRANGK
                     GLTGNHANEWRYRIGDYRLICDIQDDKMVVLALEFGHRKDIY"
     gene            44669..45274
                     /locus_tag="TV188_000045"
     CDS             44669..45274
                     /locus_tag="TV188_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1533449.1"
                     /translation="MGSTLIDESLAFNAFMKQWRISLARCGKQLTREELLSSINMLTA
                     AGICEFDLLWQRLAPKGCQRPKWSHQLERLFADTKPCLQVLSETYQLGIIANQAKGLK
                     ERLERFGISHYFALMISSSDVGLQKPDLALFRYALDQAGVLARDAVYIGDRVDNDIIP
                     AKALGMRAVRIHQGLAASSPDDRLYPSDVHISKLSDLLECF"
     gene            45742..48522
                     /locus_tag="TV188_000046"
     CDS             45742..48522
                     /locus_tag="TV188_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1533450.1"
                     /translation="MSNKKFFTYASLLALIAVPTVVEEVTAQPSAQLVYADELRLSPS
                     TDSSPVTKTDEADQPVAQSVSATEPVEALVIADKESALNPAVLADADGSQPIAVVRAG
                     QEGQPYTVTGKIISAVNGWGGHGFYIQDSQGSGLYIYPGSALGYVTGDVVQLTGTLTT
                     YKGELQLKTITKHHKINGELPTPIAEVTIPELEKASPSTLVKLSNVTVGDISSDKHET
                     SSFKVSDTAGNSVAVRLDNRTGVKTSDLLSKIGKGDVINLTAIHSTFDGKLQLKPFSL
                     EQFEVVKKVVREEEVTPLGRVVKIGQIQGASHTSPLLNQAVTVKEVVVTYLDDATHFY
                     VQDINGDNDKATSDGIRVFAQNAQVQAGDVLTISGTVEEFFGKGYDDRKQTDLTITQI
                     KASKVTKTGTAQVPAPLVLGKDRVAPANIIDNDGFSVFDPEEDAIDFWESLEGMLVAV
                     DNAKILGPMSHKEIYVLPGSSTRVLTNSGGILLPETGYNTDLIPVLFKKGKQTIKAGD
                     SYQGRLAGPVSYSYGNYKVFVDDSSRMPVLVDGQLKPEKTHIKKDLSKLSIASYNIEN
                     FSANPSSTKDEKVRRIAESFIYDLNAPDIIGLIEVQDNNGPTDDGTTDATQSAQRLID
                     AIKALGGPAYQYVDIAPENNADGGQPGSNIRTGFLYQPGRVSLSDKPRGGVNDAVKWV
                     NGELSLSVGRIDPTNPAWNSVRKSLAAEFIFQGHKVVVVANHLNSKRGDNSLYGRVQP
                     VTFKSEERRHVLARLLSQFTKEGASQQANIVMLGDFNDYEFTKTIKLIEEGDMANLVS
                     RHELSDRYSYFYRGNNQTLDNMLVSRNLLGRYEFDMVHVNSPFMEAHGRASDHDPLLL
                     QLSFGKDKPAAPSDQPKKTPAPAATTQASKAGRAQLLPKTGDKTALMVSILGLTAVFS
                     SFSLFRKCQERK"
     gene            complement(48944..49081)
                     /locus_tag="TV188_000047"
     CDS             complement(48944..49081)
                     /locus_tag="TV188_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1533451.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     regulatory      49325..49443
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            49441..49947
                     /locus_tag="TV188_000048"
     CDS             49441..49947
                     /locus_tag="TV188_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEL1533452.1"
                     /translation="MTSFTVRDYVYIALVAALYVVLTITPPLNAISYGMYQFRVAEMM
                     NFLAFYHKKYIIAVTLGCMIANFYSFGLIDVLVGGGSTLIFVSLGVALFKQYQEEYLL
                     NGLLNKAFVYFSLFFATSMITVAIELYFFGAPFFLTWFTTAVGEFASLIIGSMIIDRL
                     SKRINLRQ"
     gene            50044..52002
                     /gene="ligA"
                     /locus_tag="TV188_000049"
     CDS             50044..52002
                     /gene="ligA"
                     /locus_tag="TV188_000049"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEL1533453.1"
                     /translation="MKKRIRELTDLLNQYRQEYYTNDAPSVSDSEYDKLYRELVELEQ
                     TYPAYILKDSPTQLVGSTILTGFQKYQHQYPLFSLQDAFSREELNAFDQRIKSAFPEA
                     EYLAELKIDGLSISLVYEAGVLKVGATRGDGTIGENITENIKNIKDIPKRLSQALDVT
                     IRGEAYMSRQAFKTINEERQENGEPEFANPRNAAAGTLRQLDTRIVAKRQLATFLYQE
                     VGLETADSQQKTLERLADLGFSVNSHYLLSSSMNDIWDFIQSIEASREELPYEIDGVV
                     VKVNQLAIQEELGFTVKAPRWAIAYKFPAEEKEAEIVSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRIGDTVVVYKAGDIIPAVLRVVEAKRRDQAPMPIP
                     TACPSCQSQLVHFEDEVALRCINPLCPSLVQRSLEHFASRQAMNIAGLGPAVVEKLYS
                     AGLVHDVADIYRLSLEDLLTLDGIKEKSAEKLLAAIEQSKANSAEKLLFGLGIRHIGA
                     KASRLILEAYGDLEALLAVTAEELAQIDGLGLVIGQSLVQYFQQEQAAQLLAELKSAG
                     VNLAYLGQRPDQQAALFGLTVVLTGKLEKLNRTQAMEKLEQLGAKVTGSVSKKTDLVV
                     AGSEAGSKLAKAQQLGIRIEDEDWLLNL"
     gene            52015..53037
                     /locus_tag="TV188_000050"
     CDS             52015..53037
                     /locus_tag="TV188_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1533454.1"
                     /translation="MKKQMRARLIYNPTSGQEIMKKNVAEVLDILEGFGYETSAFQTT
                     AAKHSALKEARRAAKAGFDLLIAAGGDGTINEVVNGIAPLEKRPKMAIIPAGTTNDFA
                     RALKVPRGNPVEAAKLIGKNQTIRMDIGRAKKDTYFINISAAGSLTELTYSVPSQLKT
                     MFGYLAYLAKGVELLPRVSNVPVKITHDHGIFEGEVSMIFAAITNSVGGFEKIAPDAK
                     LDDGMFTLILIKTANLFEIVHLLRLIIDGGKHVTDRRVEYIKTSKITIEPQSDKRMMI
                     NLDGEYGGDAPITLENLKNHITFFANTDLISDDALVLDQEELEIEEMVKKFAHEVEDL
                     EQGLEE"
     gene            53046..55346
                     /gene="pulA"
                     /locus_tag="TV188_000051"
     CDS             53046..55346
                     /gene="pulA"
                     /locus_tag="TV188_000051"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEL1533455.1"
                     /translation="MDNAVIVHYHSCKGHYFQLSLWQWRDGKLGKDAYFSRFDSFGAV
                     AYLTYPAPYFLSHAYVIVKDQFWQHQTVDFRIERDYGVPKTEVWLVDGDPTVYYSRQA
                     AVASRHDGRCDVHAFDMAVNSQAFDKRWGFSGWLGFRYQPEETSFRLWAPTAEKVELI
                     LYASTDERASVAKVLPMQRGQQYSPDHHAENTCGVWDISLRGDYNYHAYCYRVYYRRR
                     TFRDTRDPYAIATTANGKRSIVIAPEHLRPQGFSVKQGKEATWRLDNPNQAVIYEMHV
                     RDFSKSETSGVSLANRGKFKGLIETGTRNAFGDSTCFDYVKSLGITHIQLQPVFDHHQ
                     FFDENGDYAYNWGYDPENYNVPAASFTSNPHEPATRILELKEVIQAYHDAGINVIMDV
                     VYNHTYSSRESAFQLTVPDYYYRMNPNGSFQNGSGCGNETASEKEMYRKYMLDSILYW
                     TNEFNIDGFRFDLMGLHDIDTMNLIRQELDKIDPRILVFGEGWDMGVGLAAEQKAKKG
                     NASQMPGIGFINDDQRNAVKGAEVYGSLEKGFVSGAPTEGLVAKSILGSDELVSYCTP
                     SQVINYVEAHDNYNLNDLLWVLNPEDSKQDHVKRVQLASAMTILMQGIYFMQLGQEFL
                     RTKLYPTGQDKELTQADRERAMNSYNAPDNVNQVDWRQVSLERETVAIMKKLIYLKTK
                     TALFSYPSFEQIRQHVYIEHAGENTGFISFTVEDERKYRLIFSSFRNRLQSSANHVII
                     ETNDKRFQDSESMLDELTAMILDITQ"
     gene            55493..57372
                     /gene="glgB"
                     /locus_tag="TV188_000052"
                     /pseudo
     CDS             55493..57372
                     /gene="glgB"
                     /locus_tag="TV188_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
     gene            57439..58578
                     /locus_tag="TV188_000053"
     CDS             57439..58578
                     /locus_tag="TV188_000053"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019785022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEL1533456.1"
                     /translation="MKNGMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVITQYQPLALNNHIGNGSSWGLDGINSGATILQPYSATEGNRWFQGT
                     SHAIYQNIDYIDSINPEYVLILSGDHIYKMDYDDMLQTHKANMASLTVAVIDVPLKEA
                     SRFGIMNTDTNDRIVEFEEKPANPKSTKASMGIYIFNWQRLRTMLVDAEKNNIDMSDF
                     GQHVIPSYLESGERVYTYNFKGYWKDVGTIESLWEANMEYIGEENALDSRDRSWKIYS
                     KNHIAPPNFITEDAEVKDSLVVDGSFISGKVNHSILSTNVQVRKGAEVKDSFIMSDVI
                     IGEGARITRAIIGEGAVIGDHVIIDGSKDVQVVGYNEVVGVPNED"
     gene            58568..59701
                     /gene="glgD"
                     /locus_tag="TV188_000054"
     CDS             58568..59701
                     /gene="glgD"
                     /locus_tag="TV188_000054"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEL1533457.1"
                     /translation="MKIDKYSAILGSSIGFAEMKGLTDTRPLANLPFDGKYRLIDFQL
                     SNLANAGVRSIYGIFRGQNIRSVFDHIRSGREWGLNSLLSHYFLGFYNTKEDSKEADK
                     DYYQQILTYLKRSGSDQTIYMSCDILCNIELGQVIHLHNANHRNITVVYKKMPTKAIS
                     KANDILDIDETDTVVDRRSLSEGQEVEKMSAGIYIVNTPWLIEQMEKEAEKENPQKLR
                     FLLRDLIVSEGALGFEYTGYLANIHSVKSYFDANMDMLDPHKFYSLLYANQKVYTRVK
                     NEESTYFDAASEVNNAQFASGSIVKGYVEHSIVSRNCRITSQARVTNSILLPKAVIGE
                     GAVIDYAIIDKSVRVAPGVTIRGSAEEPIVVAKGTEVVEDMIK"
     gene            59698..61128
                     /gene="glgA"
                     /locus_tag="TV188_000055"
     CDS             59698..61128
                     /gene="glgA"
                     /locus_tag="TV188_000055"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEL1533458.1"
                     /translation="MKIMFVAAEGAPFAKTGGLGDVIGALPKSLVKNGHEVSVILPYY
                     DVVDQAFGQQVEDVLYFYTQVGWRRQYVGIKKLVKDKVTFYFIDNQGYFFRGRIYGDW
                     DDGERFAYFQLAAIEAMEKIGVIPDILHVHDYHTAMIPFLLKEKYHWIQAYQAIRTVF
                     TIHNIAFQGQFDPGMLGDLFDVGIERYEDGTLRWHDCLNWMKAAVLYADRVTTVSPSY
                     AHEIQTPAFGQGLDQVMRMEAGKLSGIVNGIDTDLFNPARDPHLPASFSAEDLSGKAA
                     TKQALQERLGLPVRADVPLIGMVSRLTDQKGFQLVLEELPHILQQDVQLVLLGTGDPD
                     YEAAFSWFAKAYPEKLSANITFDLPLAQQIYGACDLFLMPSAFEPCGLSQMMAMRYGA
                     IPIVHEIGGLKDTVASYNAYEKTGTGFGFDQFSGFWLTQTLLFALDIYHNHKEDWQTI
                     QQHAMTKDFSWDTASLAYLDLYKSLL"
     gene            61147..63543
                     /locus_tag="TV188_000056"
     CDS             61147..63543
                     /locus_tag="TV188_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004234325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HEL1533459.1"
                     /translation="MHVTKEQFIRDFKDTLHEEQLIKVPAATAAELFTSLAKLIRKYY
                     TDTWIERNRSLTEQQQKIAYYFSIEFLPGRMLETNLLNLGILDTVKEAFADLGIDFQA
                     VKHAEHDMALGNGGLGRLAAAFMDSLATTGYPGFGNGLRYRYGLFKQRIVNGYQVELP
                     DSWFGSIGNVWEIRKDHDIVDVKLFGNVYLKANQDGKLAPIYEGAQVLRAVPYDVPQI
                     GFENDVINNLRLWDVEIPEEHELDYPTIESRRAVKDITAILYPDDSSYEGKKLRLIQE
                     YFMTSAGIQTIIKSYLKQGLPLTELHQKVSVHINDTHPAVAPAELMRLLIDDYGLEWV
                     DAWATTVKTMSYTNHTILSEALEKWDAELFKTVLPRVYQIILEIDHRFVAEMAQKGID
                     PQIIENTRIVKDNQIYMANLAIIGGYSVNGVAKLHTELLKTDTLKDFYALYPEKFNNK
                     TNGIVQRRWTQIAAPELSAAIDRTIGKGWRKDIHQLRQLSQFTEDPAVLNDFYQVKQA
                     AKQRLARYILEKTGLEVSTEAIFDVQVKRLHAYKRQLLNVLHIMKLYLDLKANPDLDM
                     VPRVFIFGAKAAPGYHFAKSVIKIINELANLINHDTSLKGKLKVVFLENYNVSLAELI
                     IPAADISEQISLASKEASGTSNMKFMMTGAITLATLDGANIEIKDEVGEENIVIFGMD
                     KDQVYDHYAKHDYYSRGLYESDPQIKAVVDAFVNGTIPNSQHEGMEIYDALITHNDEY
                     FLLEDFSSYVKAQAKIDRLYRQKDRWSKMSLINIAHSDKFTSDDTITQYAKDIWQLKR
                     "
     gene            63885..64082
                     /locus_tag="TV188_000057"
     CDS             63885..64082
                     /locus_tag="TV188_000057"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEL1533460.1"
                     /translation="MNPIFALALACFGVSLAEGFLMANLFKSASRQPEIIGQLRSLMI
                     LGVAFIEGTFFVTLVMAFILK"
     gene            64116..64832
                     /gene="atpB"
                     /locus_tag="TV188_000058"
     CDS             64116..64832
                     /gene="atpB"
                     /locus_tag="TV188_000058"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEL1533461.1"
                     /translation="MEEAKVPMVELGPITFNLTLLAVCIVTILLIFGFVFWASRQMTL
                     KPKGKQTALEYLISFVNGIGEEHLDSHLQKSYSLLLFTIFLFVAVANNLGLFTKLETT
                     SGYNLWTSPTANLAFDLALSLFVTLLVHIEGIRRRGFGAYLKRFATPWPMTPMNLLEE
                     FTNFLSLAIRLFGNIFAGEVVTGLIVQLANYRLYWWPIAFLVNIAWTAFSIFISCIQA
                     FVFTKLTATYLGKKVNESEE"
     gene            64850..65344
                     /gene="atpF"
                     /locus_tag="TV188_000059"
     CDS             64850..65344
                     /gene="atpF"
                     /locus_tag="TV188_000059"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEL1533462.1"
                     /translation="MSVTIGELIGNFILVTGSVIVLLLLIKAFAWGAIEAVLQARSQQ
                     ISQDIDQAEQARLNAQQLEKEGQANLEASRSEASQIVEAAKETGKAQETRIVAEATEE
                     ADRLKAAALTDIEHSKSEAISAVKTEMSDLTVLLAEKIMGANLDKAAQSQLIDRYLDD
                     LGEA"
     gene            65344..65880
                     /locus_tag="TV188_000060"
     CDS             65344..65880
                     /locus_tag="TV188_000060"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEL1533463.1"
                     /translation="MTKKEQALIEQYAKSLVQVCQERDTLEALQADVLAILEVFKATN
                     LAKTLSSLAVPRAKRLELVRQLQGDNIVYLNNLLEVMLQNEREAYLYQVLLRVLSELA
                     SVSNQYDVTVTSAVPLSEEQKQRVRTVVSKRLAVKTGRLIEKVDPSLIGGFMISVNNK
                     VIDTSIRRQLQAFKMNLK"
     gene            65896..67401
                     /locus_tag="TV188_000061"
     CDS             65896..67401
                     /locus_tag="TV188_000061"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEL1533464.1"
                     /translation="MAINAQEISALIKKQIENFQPNFDVTETGVVTYIGDGIARARGL
                     DNAMSGELLEFSNGTFGMAQNLESNDVGIIILGDFSTIREGDEVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPVDGLGDIETTGFRPVETPAPGVMQRKSVFESLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTSVAIDAILNQKGQDMICIYVAIGQKESTVRTQVETLRRYGAL
                     DYTIVVTASASQPSPLLFIAPYAGVAMAEEFMYNGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERSAKVSDDLGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLQEDLFNSGIRPAIDAGSSVSRVGGSAQIKAMKRVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQPLHKPLPVEKQVVILYALTHGFLDDVPV
                     DDILAFEEALYDYFDAHYDHLFETIRTTKDLPQEAELDVAIQAFKAQSNFK"
     gene            67419..68294
                     /locus_tag="TV188_000062"
     CDS             67419..68294
                     /locus_tag="TV188_000062"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEL1533465.1"
                     /translation="MAGSLSEIKAKIISTEKTSKITSAMRMVSSAKLVKSEQAARDFQ
                     IYASKIRQITTDLLKSDLTTGSDNPMLVSRPVKKTGYIVITSDKGLVGGYNSKILKSI
                     MDMIQEYHAAGDYEIISIGSIGSDFFKARGMNVAFELRGLADQPSFDQVGRIISQSVG
                     MFVNEIFDELYVCYNHHVNSLTSQVRVQRMLPISDLVAEEAAEEGVTGFELEPNRHVI
                     LEQLLPQFTESLIYGAIIDAKTAEHAAGMTAMQTATDNAKHVINDLTIQYNRARQAAI
                     TQEITEIVAGANALE"
     gene            68462..69868
                     /gene="atpD"
                     /locus_tag="TV188_000063"
     CDS             68462..69868
                     /gene="atpD"
                     /locus_tag="TV188_000063"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEL1533466.1"
                     /translation="MSSGKIAQVVGPVVDVVFASGDKLPEINNALIVYKDGDKKQKIV
                     LEVALELGDGMVRTIAMESTDGLTRGLEVLDTGRAISVPVGKETLGRVFNVLGETIDL
                     EAPFADDVNREPIHKKAPAFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLTQ
                     MGIYPAVDPLASSSRALSPEIVGEEHYAVATEVQRVLQRYRELQDIIAILGMDELSEE
                     EKTLVGRARRIQFFLSQNFNVAEQFTGLPGSYVPVAETVRGFKEILEGKHDHLPEDAF
                     RAVGPIEDVIEKAKKMGF"
     gene            69881..70297
                     /locus_tag="TV188_000064"
     CDS             69881..70297
                     /locus_tag="TV188_000064"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEL1533467.1"
                     /translation="MTQMTVQVVTPDGIKYDHHAKFISVTTPDGEMGILPNHINVIAP
                     LQVHEMKIRRVSEDDRVDWVAINGGIIEIKDNVVTIVADSAERDRDIDVSRAERAKLR
                     AERDIAEAETTHDIDEVRRAKVALRRALNRINVSKK"
BASE COUNT        20004 a        13438 c        16449 g        20513 t
ORIGIN      
        1 cgtggcgagc aaggaccaaa aggtgatcgt ggcgaacaag gaccaaaggg tgatcgtggc
       61 gagcaaggac caaaaggtga acgcggtgag caaggaccaa aaggcgatcg tggcgagcaa
      121 ggtccaaaga aggagccaga aaaagacacc aagccatcag tgccaaaggc accagataat
      181 atggctgcac caaaggctcc ggagaagaag aaccctaaag caccggctcc taagtcagct
      241 ccaaaggcat cattgccatc aacaggagac actagccaat catttgttgc agcagccctt
      301 ggctttatcg ctagcgcggg cttgctagtc ttcaaaagaa agaaaaacta agctagctaa
      361 agactgtaaa caagcctcaa ctgttacagc aagcctcttt gacatcttgc agataagagg
      421 atttcttagc gaatgaagtg tgtctaaagt cagatactct gctggactag cagtagctga
      481 tctccctgaa aatcagttat gctaaagcat tgagccttag ttgcaaggct taggtgtgac
      541 cttccaaagg aagctgcttt tgcctgtatc actttaggaa gatatctaaa agagacactt
      601 ttttcacgct gaagctaagc tagcttttcc tatgacaaat atcctataac aataaactcc
      661 aaacaaaaga gaggtcaaat ggtacctctc ttttacttag ctttaggatt gatagattct
      721 aaaggcttcc ttgtttcttg atcaagaagt ccttactgat agagtctgtc ttagccgggc
      781 ttatatggta taatacctaa tggagataag aaaagtcctt aacaaataga gtttcatcta
      841 ttgttacagg agcaaccaag tgaaaggaga tgctacatgt cagataaaca aatcaatttg
      901 gttattgtta caggaatgag tggcgccggc aaaacagttg ccattcaatc atttgaggat
      961 ttggggtatt ttactgttga taacatgcca ccagctttag tgcctaaatt tttagagctg
     1021 cttgagagga ccaatgaaac ccaaaaggtt gctctggtag tggatatgcg cagcagacgc
     1081 tttttcaagg agattaactc tatcttagat catattgagc taaatgccaa cctcaagcta
     1141 cggatcctct ttcttgatgc gactgatagt gagctagtgt cacgctataa ggaaactaga
     1201 agaagtcacc ctctggctgc tgatggtcgg gtgcttgatg ggattcgacg agaaagagag
     1261 ctgttagtcc cgcttaagag catgagtcag catgtggtca ataccaccga tctaacccca
     1321 agacagctgc gtaaggtgat ttcggatcag ttttcaagcg agtcagacca agcctcattt
     1381 agaattgagg tgatgagctt tggctttaaa tatggcctcc ccttagatgc ggaccttgtc
     1441 tttgatgtgc gctttttgcc taatccttat tatcaggtgg cgctaagaga gcagacaggg
     1501 cttgatcagg ctgtttttga ttatgtgatg actcatcaag agtcagaggc cttttataat
     1561 catttgttag gcttgattgt tcctattttg cctgcttatc aaaaggaagg caaatcagtg
     1621 ctaaccattg ctattggctg tacaggtggt cagcatagaa gtgtcgcctt tgcccatcgc
     1681 ttggcccaag acttgacagc agactggccg ctgcatgaga gtcatcggga catcaatcgt
     1741 cgtaaggaaa cggtaaatcg ctcatgagaa atcctaaaat aacggtgata ggaggaggaa
     1801 caggtattcc tgttatccta aaaagccttc gcaaggaggc ggttgacatt actgcggtgg
     1861 tcactgttgc tgatgatggt gggtcatctg gtaagctgcg caatgccatg cagcttaccc
     1921 cgccaggtga tttgcgcaac gtcttgttgg ccatgagtga catgcctaag ttttatgagc
     1981 gtgtgtttca gtatcgtttt aatgaggcag atggtgctct agctggtcat cctctaggca
     2041 atttaattat cgcaggtatt tctgagatgc agggatccac ctataacgct attcagattt
     2101 tgacgaaatt tttccatatc accggcaaga tttttccctc aagcgagcag cccttgacac
     2161 tgcatgctgt ctttaaggac ggtcatgagg tgtcaggaga aagctctatt gccagctacc
     2221 aaggcatgat tgaccatgtc tatgtgacca atacctacaa tgatgacctg ccaaaggcca
     2281 gtcgtaaggt ggttgaggcc attctccaaa gtgatatgat tgtgcttggt cctggttcct
     2341 tgtttacctc tattttgccc aatcttgtaa ttccagagat caaagaagcc ctgagagtaa
     2401 ccaaggcaga ggtggtttat atttgtaaca ttatgaccca gtacggtgag acagagcaat
     2461 tttccgatgc ggatcatgtt gcggttttaa atcagcatct gggcagggac ttaattgaca
     2521 ctgttttggt taatgttgag caggtgccaa aaagctatat gaattccaac caatttgacg
     2581 aatatctggt ccaagtagag catgactttg caggtctgtg taagaccgca aagcgtatca
     2641 tctcgtctaa ttttctgcgt ttggagaatg gcggagcctt tcatgacggg cacttggttg
     2701 tagaagaatt aatgaaccta gttaggataa ccaagctatg agttttacga caactgttaa
     2761 agaagaattg attcatttat ctgcttctga tcaaacagaa ttatcagcaa tcatcaagct
     2821 ggctggtagc ctaggcttgg ctaatcagag cttgaatttg tctatcacaa ctgaaaacgc
     2881 taagattgct cgctacatct atgcgcttat cgaagacacc tatcatatca ttccagaaat
     2941 caggtaccat caaaagacca acttgaaaaa aaatcgtgtc tatacggttt atttggataa
     3001 gcaggtggat aagctcttag cagatttaaa gctggcagat tctttttttg gcattgagac
     3061 aggtattgag cagcaggtca tgtcagatga tgatgctggt cgggcctatc tcaagggtgc
     3121 ttttttagcg gcagggactg taagggatcc agaatccggc aagtatcagc tagagatcta
     3181 ctctgtctat ctagaccatg ctcaggattt ggcccagctc atgcacaaat tcatgctaga
     3241 tgccaaggtt atcgagagaa aaaatggtgc agtaacctat ttgcaaaagg ctgaggacat
     3301 catggatttt ctcattatta ttggtgccat gtcgtgtaag gaggagtttg aggctgttaa
     3361 gcttttgcgt gaggcgagaa atgacatcaa tcgggccaat aatgcagaga ctgctaatat
     3421 tgctaaaacc atcaccgcca gcatgagaac cattaataat attatcaaaa tcatggatac
     3481 gattggctta gacagcctgc cagttgagct gcagcagatt gcccagatga gagtagccaa
     3541 cccagactat tctcttcaac aaatcgcaga ttcgcttgac tttgccatca ctaagagtgg
     3601 ggtcaaccat cgcctgcgaa aaatcaataa gctggcagag gatttataaa gacagcttag
     3661 cctttttcag gctgataaaa aagggggtaa ggtgatacga acaagccgcc ttttaaggca
     3721 tgccttgttg agctttctct aggctgttga tggagtgatc tcaaggcgct tttgttactg
     3781 tcattccaac aggctatctg attttgggat gacttcttac taataagctt ttctaatggc
     3841 tggctgacaa cgattagcga tatagttaag gcttatcgtg attcaacaag aggctttagt
     3901 ctcttttttg cttgtcagaa ttattttttt aggcttttct tacaaatgag aggacaatgt
     3961 gacaatctgt ggtatgatat tagtaatgaa tacaaaggag aacaaatcat gtcatgcaca
     4021 actattcttg tcggtaaaaa agcgacctat gatggatcaa caatcgttgc tcgtacagag
     4081 gattcacaaa atggggaatt tacccctaaa aaaatgacag ttgttagacc aaaagaccaa
     4141 cctagacact atcaatctgt cttgtctagc tttagcatgg agctgccgga tcagccgatg
     4201 gcttatacct cggtgcctga tgccctagga aaggacggta tctggggaga agcaggtgtc
     4261 aataccctca atgttgctat gtcagcaact gagaccatta cttcaaatgc tcgcgttctt
     4321 ggagcagatc ctcttgtttc ctctggtatt ggagaagagg acatgctgac cttggtgctt
     4381 ccttatattc ggtctgcaag agagggtgtt cttcgtttgg gagctatcct agaagcatac
     4441 ggtacctatg aggctaacgg tgttgccttt tctgatgagc atgagatttg gtggctggaa
     4501 acaataggtg gtcatcattg gattgcaagg cgcgttcctg atgatgctta tgtcactaat
     4561 cccaaccagt ttggccttga tcactttgaa tttaacaatc cagaggaata cctgtgttcc
     4621 aaggatttaa aggactttat tgccaaatat catctagatt tgacctatag caacgagcat
     4681 tttaaccctc gctacgcctt tggtagccaa agagataagg atcgccatta caatacacca
     4741 cgcgcttgga ttatgcagca atactttaat ccggagtttc tgcaggatcc gcgcagcttt
     4801 gaacttcctt ggtgccaaag acctgatcgc aaggtgacca ttgaagacgt taagtacgtg
     4861 cttagcaatc attatcagga caccccttat gatccttacg gcccagaggg aacgccgact
     4921 agtcgaaaat cctttaggcc gattggtatt aaccgtacga gtcaaactgc tattttacat
     4981 atccgtccca acaagcctaa ggaaattgct gccattcagt ggatggccta tggttcgatg
     5041 ccctttaata caatcgttcc gctattcacc caggtcaaga ccattccaga ttattttgca
     5101 aacactgttg aaaatgtttc cacagacaat ttctattgga ccaatcgctt gattgcagcc
     5161 ctggctgatc ctcacttcaa gcaccatgaa gcagatttgg aggactatct cgaaaaaaca
     5221 atggccaagg gtcatgccat gctgcatgct gttgaagcag cgctagtaaa aggtcagccg
     5281 gttgacctag aagaggccaa ccaaggcatg agtgatgaca ttcaggcaga tacacaggct
     5341 ctgctcaata agatcctctt tgatgctagc aatctcatga ccaaccgctt tagcctaagc
     5401 gactaagtaa tctcaatagt caaacgagct catatcatta tagatatggg ctcttagctt
     5461 gaaaaggata gtagagcggt cttatagtca gactaattaa tggtaacgat gagtccagtt
     5521 aaggtaaaaa aagagcactt agctaatgca aaaaaagtaa aaaacttgca aaagaatgat
     5581 attgtgttat acttaaccag taaatattaa gagctatttg cgatatgata tatagaggag
     5641 gaatcatgaa aaagaagtat cttttaatga tgagtgtgct cggtgtcttt tttgcgggac
     5701 agatcagtca agcaaaacag gtcctagcag atagtaaggt caaaattgtt accaccttct
     5761 atcctgttta tgaatttacc aaaggcgttg tcggaggtga gggaaatgtg tctatgctga
     5821 tgaaagcagg aacagagcct catgattttg agccgtcaac aaaggacatc aaaaagatcc
     5881 aagatgccga tgcctttgtt tatatggacg ataatatgga aacttgggtc cctgatatga
     5941 agaaatcact gacttctaag aaggttacgg tgattaaggg aacaggagat atgctattgg
     6001 tagctggctc tggtcacagc cacgagcatg accatgacga tgccgataaa aagcatgatc
     6061 atgaccacga cgaggaagga cacagccatg cttttgaccc gcacgtatgg ttgtcacctt
     6121 atcgcagcat caccgttgtc gaaacaattc gtgatggtct atctaaggcc tatcctgaca
     6181 aggctgacca cttcaaatct aatgccgctg cttatattga aaagctcaag gaattagata
     6241 aggagtatag tgacgctttt tcagctgcca agcaaaagag ctttgtgact cagcacgcag
     6301 cctttggtta tatggcgctt gattatggct tgaaccaaat ctcaatcaat ggtgtcacac
     6361 cagatacgga gccttcagct aagcgcattg cagagctatc aaaatacgtc aaaaaatatg
     6421 acattaacta catttatttt gaagaaaatg cttcaagcaa ggttgccaaa accctagcca
     6481 aggaggctgg tgtcaaatca gctgtcctta gtccgcttga aggcctaact gaaaaggaca
     6541 tgaaggccgg caaggattac tttaccgtta tgcgtgaaaa cctcaaaacc ctacgcttaa
     6601 caactgatgt agaaggaaaa gaaattcttc cagaagagga taccactaaa actgtttata
     6661 atggctactt taaggataag caggtcaaag accgcaaatt gtctgattgg tctggtaact
     6721 ggcagtctgt ttacccattc cttcaagacg gtacattaga tcaggtatgg gactataagg
     6781 ctaaaaaatc taaaggaaaa atgaccgcag ctgaatacaa ggattattac accactggct
     6841 atcagacaga tgtcagtcat atcaagatta atggtaagaa aaataccatg acctttgttc
     6901 gtaatggtga aaataaaacc tttacttata agtacgtcgg taaaaagatt ttgacctatc
     6961 caaagggcaa tcgtggcgtg cgcttcatgt ttgaagctaa ggagccagac gctggtgaat
     7021 ttaaatatgt tcagttcagt gaccatgcta tcgcaccagg taaggcggag catttccacc
     7081 tatactgggg tggtgacagc caagaaaagc ttcacaaaga gctagagcat tggccaactt
     7141 actatgatgc ggacctatca ggtcgtgccg ttgcccaaga aatcaatgct cattaaccac
     7201 tcaaaagact aggcagttca atcggcctag ttttttcttg tcttagttgc tgtataggac
     7261 ctaaatgctg atagctggtc ttaagattta tttttaattt ttctaactat atttaggttg
     7321 tatttgtttg ttaataccaa atccattgtt ttagggatta tatagaatta atatgttaaa
     7381 tattttaata tttttcaaaa aagtattgac ttttagattg taatataata ttatttaagt
     7441 ggttataata agttagaggt gttagtatga taaaggaaca gccactctac ttacaaattg
     7501 ttgatgtatt agaggtcaaa attagaaata ccatgtcagc taatgataaa ttgttatcag
     7561 aacgagagct aagtgactta tttggtgtta gtcggataac cattagattg gcacttaagg
     7621 agctagagct gcgtgggctt atttacaaac agcagggcaa ggggacctat gtatcaggca
     7681 taaaggagcc tgctacagac ctgtcctcag cctatagctt taccgaagag atgaaaaagc
     7741 aaggtcgtaa gcctcaaaca gtcattcttt catttgaaaa aatcaagacc acagcttact
     7801 tgtctggtat gttagattta gatgttgata ctgatgtttt tgagctagag cgtctaagga
     7861 ttgcagatgg aaagccatta atgtttgagc gcacttatat acctgaaagg ggatttgagg
     7921 cgataacgat tgatttattg gaaaaaaagc ccttatatga tgtgtttgct gaggattttc
     7981 aggaagctat ccgattggct gatgaggagt tttacgctag tatcgctcta gattatgaag
     8041 caaagctatt agggatcaaa aagggggatc ctgtgctgca tattatgcgt aagacctata
     8101 atgagaaaaa taggctaatc gaatttacct ttagtattgc tagagcagac cagtttaggt
     8161 accgtatcca gcaccaccct aacaagaaga tataggaggt aaggaaatgt ttacaaaaac
     8221 acaagcagaa ctagagctac ttggcgcagc tatcaccact agagaaatca agcagcagcc
     8281 agagctatgg tcagaggtct ttgagtcttt tctgaagcaa aaaaaagacc tcttagcctt
     8341 ttttgacagg attattgaaa gcgctaacag aaacaaggta aaaattattt ttacaggagc
     8401 tggaacttct gaatacattg gcaataccat ttgtcattat ttggagatga ctggtgacag
     8461 ggaaaattat ttatattaca gcattgcttc cacagacctt gttgcagctc caagccagta
     8521 tctctttgaa gaggatacag tcgtgcttgt ttcctttgca agaagtggca atagtcctga
     8581 aagtgtcgct gctgttagtc ttgttaatca gctggtgtca aatccttatc atttggtgat
     8641 aacctgtgcc aaagaggggg ccttagctca aaatgctaag aaggacaaaa ggagctattt
     8701 attcttgctg cctgaggcct caaatgacgc tggctttgct atgacgggaa gctttagctg
     8761 catgatgcta gcggccttgt tgatttttga tcaagcgcat tcccttgagg agaaaaaatg
     8821 ctatttagat cagattgtag gtatggtggc agctattatt cagcaggagg ctgatttaca
     8881 aaagctggtt agcttagagt ttcaacgctt ggtttacctg ggatcaggag ccttagcggg
     8941 gcttacgcaa gaggctcaat tgaagatttt agaattaaca gctggcaaaa ttgcaacagt
     9001 ctatgactcc tcaatgggct ttaggcatgg tccaaagtca tttattgatg atcagacatt
     9061 ggttattggt tttgttagca atgatcctta tacgagaagg tatgaccttg atgttttaga
     9121 agagataaga gaggatgcta ttgctgttga tacggttgca ttacagcagc aaggaggtga
     9181 gggctttagt gggcattgct ttggcttaga ctcgtcaatg ctattgccag atgcttattt
     9241 ggcctttccg cttgttttta tcgcccaaac gcttgctttg ctgtcgtcta ttaaggttaa
     9301 taatttacca gatactcctt cggccacagg aacggttaac agggttgtcc aaggtgttaa
     9361 gatttatcac tattttaagt aggagaacaa gatgtaccat ttatcaaaag ctaagtatcg
     9421 tcttcttgaa aaggtcagtc gtaagggcat catttcggcc ttggcctttg atcaacgcgg
     9481 ggttttaaag cgcatgatgg cagcccacca agacacagag ccaactcctt ggcaaatcga
     9541 agccctaaag gctctggtat cagaggagct aaccccctat gcctcctcta tcctgctaga
     9601 ccctgaatat ggcctgccag ccaccaaggt gcgtgatgag aagtctggct tattattagc
     9661 ctatgaacaa accggctatg acacaaccac cactagccgc ctgccagatt gtctggtgga
     9721 ctggtcagtc aagcgcctca aggaggccgg agctgacgca gtgaagttct tgctgtacta
     9781 tgatgttgat ggtgatgagc gtattaacca acaaaagcag gcctatatcg agcgtatcgg
     9841 ctcagaatgt caggcagagg agataccatt tttccttgag ctattgacct atgatgaggc
     9901 gataacagac aatcagagtg tagcttttgc caagctaaag gcacacaagg ttaatgaggc
     9961 catgaaggtc ttttcaactg agcgctttgg ggttgatgtc ctaaaggtag aggttcctgt
    10021 caatatggcc tatgttgagg gctttgcaga gggtgaggtt gtttacagca aagaggaggc
    10081 tatgcaggcc tttcgtgacc aagaggcagc tagtcacttg ccctatattt atttgagtgc
    10141 gggtgtatca gctagtctgt ttcaagagac cttggttttt gcggcagagg caggagctag
    10201 gttcaatggt gtgctgtgtg gtagggccac ttggtcagga gcagtagcgg tgtacatgtc
    10261 agagggcgag gaggcagcgc gtcaatggct tcgcacagag ggttttgaaa atattgatcg
    10321 tctcaatcag gtgcttgaga aaacagccag cccttggaca acaaagctta ctcttgatga
    10381 agcctagtaa aggcatgata aaagcaatac taggacattg cttctgtatt attggtaatc
    10441 actggaggac aaggcgtact tgaaaaattg ccaatgcttg taggactcgg tgtactctag
    10501 aatacggcca ttatctgtcg accgagtgag cttggtttga aggacacaag gagtgttgtc
    10561 tatcatgttt aaaaatgtag cgacatcttt aggcatgtga tccgtcagct gtgtttgctg
    10621 ggtgaagctt tgtgatcgca tttgaatgtg aaaatccaaa aagaagcgct tataaagcga
    10681 ctggtaatca gctaaatcac gctcagggca cagcaggtaa tcatgaggaa tataagatag
    10741 ctggtataaa tagggctgct gattaatcgt tcgtgtacgg gagatggtgt agtaaaattc
    10801 cgttttatga agtttcaaga gatttagata gtagggatca tttcccttaa ctacactaag
    10861 gacagtcacc tcctcttttt gatccttaaa ggtacctaga taggaaaatt ggactagctg
    10921 ttcttttctg gtacgggtaa tgaaggttcc aagtccctgc cttcttctga taaagccttc
    10981 tttttctagt tctttaaggg ctcgaatgat ggttatggag ctaacatgaa agcgtttaat
    11041 cagctcggct tcggtataaa atttgtcccc ggtatggtag tggccattca gaatttggtt
    11101 ttgcaattct tctttgatta gtcggtactt tgggtatttg atggtcatag ttactcactc
    11161 aataattgtt tagtacgatt atagcaaaaa tagtaagctg atgtcatatc ttaccagtta
    11221 ttgctcagat agcttgtcaa tcagtcattg atcaaaggct gatggttaat gaataaaagg
    11281 agataatatg aagcaatttt gcataaagga gcagttttac cttgatggca agccgtttaa
    11341 gatattatca ggtgccattc attactttag aatagctcct gatagctggt ctagggtgct
    11401 ttatcagctg aaggccttag gctttaatac agtagaaacc tatattcctt ggaatatgca
    11461 tgagccaagg aagggacagt ttacctttga ggggattgca gatgttgagg catttttgga
    11521 tttggcacag gaatgtggcc tatatgctat tgtcagaccc tctccttata tctgtgctga
    11581 atgggagttt ggtggtttac cggcttggct attaactgaa aattgtaggc tcagatcaag
    11641 cgatgaggtc tttcttaagc atgtatcaga ttattatgat gtgttactac caaagctggt
    11701 gaagcgtcag ttagataatg gcggcaatat tctgatgttt cagcttgaaa atgagtatgg
    11761 ttcttatggt gaagaaaagg cttatttaag aaaattaaaa gagcttatgc ttgctaaagg
    11821 cattagtgcc cctctcttta cctcagatgg gccttggcca gccacgctag catcagggag
    11881 tctgattgac gatgatgttt ttgtgacagg caactttggg tcaaacgctt caaagcaatt
    11941 tgccagtatg caggattttt tccaagcaca tcaaaagcaa tggcctctga tgtgtatgga
    12001 attctggttg ggctggttta atcgctggaa tgagccaatc attcgaaggg actccaagga
    12061 agctgttgat gcaatcatgg aagctataga gctaggcagc attaaccttt atatgttttg
    12121 tggtggcact aattttggct ttatgaatgg ctcgtcagct cgtctgcaaa aggatttacc
    12181 acagataacc tcctatgatt acgacgcatt actagatgag gcagggaacc cgacaaagaa
    12241 atataccctg ctgcaagaac gtctcaagga gtgttaccct caattatcct ttgcagagcc
    12301 aatgatcagt tctacgatgg ccttagagtc tatcaagttg tcggcaaggg ttagtctttt
    12361 taagacaatc aaaaatgtaa gcgctatcaa gaaaagtttt tatccttgta atatggagga
    12421 gctagatcaa ccaacgggct acctactgta tagaacgcac ctcgctagac atagcaagga
    12481 ggagcggctc agggtcattg atgctagaga ccgcattcag ctctttttag atgaaaagca
    12541 cgtgaaaacc cagtatcagg aggaaatcgg tcaggatata ctgatacatc aagagggtga
    12601 gaccacacag cttgatattt tagtcgaaaa tatgggacgt gtcagctatg ggtacaagct
    12661 gacagcacca agccaacaaa aaggattagg cagaggctta atggctgact tgcattttgt
    12721 aggtgattgg gagcattttc cactagattt tcaagagctg gattggattg atttttctgc
    12781 aggttggacc gatgaggtgc caggatttta cgcctatgat tttgattgtc agcagccggc
    12841 agatacctac cttgatttga gtcaattcgg aaaaggaatt gcccttgtaa atggtgttaa
    12901 cctaggacgt ttttggaagg tcggtccaac attatcgctt tatattccta agggactatt
    12961 aaaacaaggt caaaatagac tgctgatatt tgaaacagaa gggcagttta gtgagtcaat
    13021 tcgtttaact aaggaaccaa tttataaata gataaaagga gaaaacttat gacaattgtt
    13081 gcagcacgta ttgacggccg gttaattcat ggtcaggtag ctaatctatg gacgacaaag
    13141 ctaaacatta gccgtatcat ggtggtcgat aatgaggtga ttagcaatga ccttgaaaaa
    13201 acagcactga agctagccac acctagcggt gttaaattat ctatcttatc tgttgaaaaa
    13261 gcagccaaca atattttgga agggcgctat gattctcaac gcttgttgat agtagccaga
    13321 aagccggata gctttttgga gctgattcaa aaaggggttg ctatttcaga gttaaatgtc
    13381 ggcaatatgt cacagacacc ggagactcgt ccagtaacgc gttctattaa cgttgtagac
    13441 gaggatatag aggcattcaa ggctatttca gccaaagggt gtcatctcat tgcccaaatg
    13501 gtgcctaatg atgccccagc agactttatg ccgctgttgg ataaggttga ttaagatgtg
    13561 tcaaatcaaa aacgaatctg tttcaggagg taaaagctta tgattcaatg gtggcaaatc
    13621 ctattattaa cactctactc agcttatcaa atattagatg agctaacaat tgtctcttct
    13681 gcaggctcac ctgtatttgc aggatttatt tcaggtatca tcatgggaga tgtgcaaacc
    13741 ggtctttgga ttggtggtag ccttcaattg atggtgcttg gtgttgggac ctttggagga
    13801 gcttcgcgta tcgatgcaac ctctggtgcg gttattgcga cagccttctc ggttgctcaa
    13861 ggcatagagc cagaattagc gatttcaacc attgcagttc cggtagcggc cttgctggtt
    13921 tatactgata ttctaggacg cttttcaacg accttctttg ctcaccgtat tgaccgccat
    13981 gttgaaaact ttaactaccg aggcatcgag cgtgattacc ttatgggagc tgtaccttgg
    14041 gccctatcac gtgctctgcc ggtattttta gcggtctctt taggtggtgg tgcggttgat
    14101 acagttgtta agttcattga ccattatgaa tggctagcaa atggtctaac tcttgcagga
    14161 aaaatgcttc caggcttggg ctttgcgatc ttgcttcact acctaccagt taaacgtaat
    14221 ctccattatc tggctttagg ttttggcttg acagcaatgc taacaaccat ttacaccaac
    14281 cttcaggtag ctggaggcgc ccttgcagga gtagccaagg atttcaatgc cgcaccattc
    14341 aaggggctgc caatgattgg tattgctatt attgggcttt ccttggcaac cctccattat
    14401 aaaaatggtc aacaagcacc tgtagctgaa caaaaacctg gggtatcaga aagtggggaa
    14461 attgaagatg acgaaatcta attataaatt aaccaaacag gattttaatc aaatcaataa
    14521 gcgcagcctg ttcacattcc aatggggctg gaactacgag cgtatgcagg gctctagcta
    14581 tctttacatg attttaccac agcttcgtaa gatttatggc gatggaactc cagagctaaa
    14641 agaaatgatg aagacgcaca cgcagttttt taacacatca aatttctttc atacgattat
    14701 cacaggaatt gacttggcgt tggaggaaaa tgaaggactt gcctcaaaag atgctgttaa
    14761 tgggattaaa acaggcttaa tggggccatt tgctccaatt ggtgattcgg tctttggctc
    14821 cttagtacca gctattatgg gctctatagc cgcaggtctt gctaaagaag gggtttggtc
    14881 agggattact ggtgtattga tgtgggtatg tactcagatg atcatcaatg tgtttcgttg
    14941 gaagcagctt gaaattgctt ataaagaagg tacaaagctc gtcaccacca tgcgtgataa
    15001 gctaactgct gtagtagatg cagcctcagt catgggagta ttcatggtag gggccttaat
    15061 tgcaacaatg attaattttc agtttaccgc agcacccaaa attggagaga aagttatcaa
    15121 tattcaagat ttaattgata ccatttttcc acgtctagtt ccagccttat ttaccggagg
    15181 tatcttctgg ctgctagggc gtaagggcat gtcaccaact aaggcaattg ttgtgattat
    15241 tttatttgcc ttagtgatgt cttatttcaa tattttagga gtatagctga tggcgcaaac
    15301 cttaattctc attagtcatg gagctttttg tcgagagcta aaacagagta cagaaatgat
    15361 tatggggcca caggacaata ttttaacagc agagctgcaa ccaaacgaag gtgccgatga
    15421 ctttaaagaa aagcttttaa ggctaattgc aggtttagat gacgtccttg tgtttgcaga
    15481 tttgatgggt ggaacaccct gtaacgttgc cagtcgtttg ttaatggaag gacatcagtt
    15541 tgagctgtac gcaggcatga atatgccaat ggtcattggt ttcattaatg cctgtttgat
    15601 cggtgaagcg tttgatttca aagcctttgc ctgtgacaat attcaccatg tcaataccat
    15661 tatttcagct ctagcagatg atgatgacga ctaaccaagc tcgcttattt gtcacgcacc
    15721 ttacggagcg aaacggacca agagccgcat aatcaaaaaa gacactgcca aatcttggca
    15781 gtgtctttgc tgtaagctta ttttgctgcg tttgcgtctt tgagaccgta tttcttgttg
    15841 aaacgatcca cacgtccatc ggcttgtgta aacttttgac gacctgtgta gaatgggtgt
    15901 gagtctgatg aaatttctac acgaacaaga gggtaagttt ccccttcaaa ctcaatggtt
    15961 tctttagagg tcttagttga accgctaagg aatttgtagc ctgtagttgt atcaaggaaa
    16021 acaactggac gataatctgg atgaatgtct tttctcatct taaaaaagtt cctttctgcc
    16081 atgatactgt ccgtatcata gttattaact actctagttt aacaaaagtt agtaagcttg
    16141 acaagctttt tctatcacta ttcatcaata agatgataag tcttatgtta agagatcaat
    16201 cagctcttgg tagatttgct cattttcctc taagcctgat gacgtggcac cgctagcaag
    16261 agggtgcccg cctccttgat gacgcttagc aataccattg atgacctttt ctttactgcg
    16321 catgcgtact cggtactggc catctggcag ctcaacaaag ataacccaag cctgcaccac
    16381 gtctattttt ccaggagcag agacaatcgc tgagctttct gccaagctaa taccaaagga
    16441 atttaggacc tcctggctaa gcagtaggcg ggctgcacca ctgtcatcta tatcaagctg
    16501 ctcaaaaaca tagccttgta gcttggcaat tttaagtgga aaggaatcca tctgcctcga
    16561 aatagcagca aagtcaaagg cataatttct taattggctt gcaatggcca gtgttttact
    16621 gcttgttgag gcatagagaa agcgtcctgt atctcccaca atgccagtat ataatagtct
    16681 agctgcctca tcagttaaag ccaagccttg gctaaaggca aattcagcaa taatctcact
    16741 agcacttgag gtcttggtgt caacgtagga gagatcacca tagacatcat cgttagggtg
    16801 atgatcaatt ttaatgaggc aagcgcccat tgtgtagcgc tcatcatcaa tgcgggggcg
    16861 attggcagtg tctgtaacaa tcactaaagc ttccttataa tcatcgtcgg acacctgatc
    16921 catgagacta atccaagcca gactaggctc atcaaagcct gttatcagga cctttttgtc
    16981 agggaaatta tgcctgataa tctctttaag tcctgcttgg ctccctagag catctggatc
    17041 ggggttttgg tgccgatgaa tgatgatggt ttgatagtgc ttaatgtgtt ctaaaatagt
    17101 ttgaaacgtt gtcataggta tcctttagtt tttgatcata tcaatgtgag gaatattgtc
    17161 ttccagataa atctcagaga ctgctttaaa cccaaatgag ctgtaaaaag gctcaagata
    17221 agcctgcgct tgagcgtaga cgggaagctt tggaaagtgc tgttgacaat aggctaaggc
    17281 ttgatgaact aagtcacgtc ctagtcctgt tcgccttgca ttttgtgcta ccagtactcg
    17341 tcccagcttt atgctattgt cagttgggat taagcgacag taggccctaa gctctgaatc
    17401 aacctgcttg aaaagatgga tagctttttg atccaaatcg tcaatatcag gatagggaca
    17461 ttgctgctca accacaaaaa cagccacacg ctctttatag atggcaaaca attcatcttt
    17521 tgttaactga tcaaatgctt taacaaccca cattagctag cctccaaaat cactggtaca
    17581 atttccttta tgataacata atagcatata tcagccataa tggaacgaaa aaaacctgac
    17641 tcttaatgga cgatgtcgtg atgataatta catcttgtct caaaagctgg taatcatcac
    17701 aggcacagaa aaatgtgccc cttctgttgc tttttgagaa aaagttcact tgctttttgg
    17761 tagttttttg gtatcatact aaaaaataga cttaattaag gagatacagc ttggaaacaa
    17821 aagatttaaa gaagcttgct aaagctgagc tgcactgcca tttagacggt tctttgtcat
    17881 tagacactat tcgtcagttg gcggctttgg cgcaggtaga tgttcctcaa gatgattctg
    17941 agttaaagca gctggtaacc gcaccggaaa cctgtgaatc cttgatggat tatttaaaaa
    18001 cctttgatgt tatcagacca ttattacaaa cgcctcaggc tttaacattg gctgcttatg
    18061 atgttgtgaa gcaggctgcc cttgaaaatg tcatctacat tgaaattcga tttgctcctg
    18121 agttgtcaat ggatcagggc ttgaccgcca ctcaggtggt agaggcagtt ttaaaaggac
    18181 tcgagcaagg acaaaaagag tttggcattg tcgctaaggc tattgtgtgt ggcatgcgtc
    18241 agtcctcact agacattagc agagagattt ttgcaaatgt cttagagtgg gccaataaag
    18301 gcttggtagg ctttgatttt gcaggcaacg agctggactt tcctccagct gtcttagcag
    18361 atttgatcaa agagacgcag gcctatgggt taccatttac gcttcatgct ggtgagtgtg
    18421 gctgtccaaa ctatattgtt gatgctattg atttaggtat caaacgctta gggcatgtga
    18481 cggccattca taaccaaaag gatttattgg ccaagtttat cgccaatgat gtgacagcag
    18541 agctgtgctt cactagtaat ctacaaacca aggctgctag gactgttgag gactttcctt
    18601 atatgcagct aaggcaggct ggcgctaaat tatccattaa cacagacaat cgaacagtat
    18661 ccgataccaa tctgacaaag gaatatgaac tgtttgtcaa gcactttgag acaagcgtca
    18721 cagacttttt agagcataat cgtgatgcta ttaaggctag ttttgccagt ccggctgaaa
    18781 aagaagcttt attggatcgt ttggaaaagg cttatcagtc ttacatcaag aaataatgct
    18841 tttcttggca aagtatgata aaatatactg acatttagtt attttgggag gaaattatgg
    18901 cattagccaa aatcgtttat gccagcatga caggaaatac tgaagaaatt gctgatattg
    18961 ttgctaataa attgcaagaa ttgggacatg atgttgaggt tgacgagtgt acaacagttg
    19021 atgcttcaga gcttgaggct gctgatatgg caatcgttgc gacctatacc tatggtgatg
    19081 gggacttacc agatgagatt gtcgactttt atgaggactt gcaggatttg gatttgtcag
    19141 gcaagatcta cggtgtcgtg ggctctggtg atacctttta tgattatttc tgcaaatcag
    19201 ttgatgattt tgacgaacag ctcgctgcca ctggtgccac taagggagct gactcggtta
    19261 aggttgattt agctgctgag gaagaggata ttgctcgcct agaatccttt gctgagcaaa
    19321 tgtcacaggc attagaggca taagtaagac ttttgataca gattggtaaa acggtcagtg
    19381 gaggcttgcg ttttttacca ccaaatgcat gaaaaactga tattttctga tcgttttttc
    19441 atgactatgt gctctttttc aagaaaagtc atgccattat tagcctgaat gcaaacaatt
    19501 gatagtgtca aaatgttgat catatagtaa aaaaatgcat gtgactagaa agcagttaca
    19561 tgcattttcg tcatgcgttt gtcgtgaggc attttggggg ttacttgctt actgagctga
    19621 aattcactat aataaaaaga taaataaaga aaagaagaag ttaggtgaat gatgggatta
    19681 gagaccatac gacaagacat taatgctgtt gatcgtcagt tgattgcttt gctggaaaag
    19741 agaatggtct tggctgacca agtagcggcc tataagcagg tacatgatgt gccagtgctt
    19801 gatcaagagc gagaggctga ggtcctaagg agcgtgtcac agcagattcg gcataaggcc
    19861 tttgagcctg ccattcttga gctatttaag acaattatgg cagtatcaag gcgttatcag
    19921 gctgagcaaa tagcggttgg ttcaaatgat gatgaagcct attaaaaaca atcaagacat
    19981 cagtataggt gataatgtct atttggcttt tgcagccctg ctcgttgggg tggtggtagg
    20041 tgtgatagat actgtttttg gacaaggctt gttgctcttg tctgctgttc gtgatgctca
    20101 tctcatttac ctgttaccct gcttagctct tgctggactt gtgattgtgt tcttatatga
    20161 gcaatatggc caaatcgcta agcaggggat gggcttagtt tttgatgtgg ggaatggtga
    20221 aaaaacaaga ctaccactgg tgttgattcc gttgattatc ctctcaacct ggctgacgca
    20281 tttatgtgga ggcagtgctg gtcgtgaagg cgtagcggtt caaattggag cgacaggtca
    20341 catttttttg gacgtcttag acatcttaag gacaagtcac agctgttttt agtcatggga
    20401 atggccgcag gctttgcggg cttatttcaa acgccaatga cagcggttgt ttttgcctta
    20461 gaggtcctgt tgctaggaaa tataagctat ttagccttgc taccttctct tatagcagcc
    20521 tttaccgcct cttggacctc tcattgccta ggcttagaaa aattttcagt cccgatagcc
    20581 aaggccttga aaatcacccc gataaccttt gggaaattag tgctactagg ccttattttt
    20641 ggcttggctg gtaatctttt tgcctccttg ttagcaaggg ctaagccata cattgcagca
    20701 aggctgccaa atccttatta tcgtgtgttg cttgttggtg gttttctatc gcttagcctg
    20761 ctgctgtgcc attacgggcg ctatagtggc ctagggacta acttaattac agcggccttt
    20821 agtcatcagc ctattgctaa ttatgattgg ctattaaagc tcttgtttac cattatcact
    20881 ctctcggctg gctttcaggg cggtgaggtc actccacttt ttgctattgg tgcggcttta
    20941 ggaattgtcc tagcaccatg gcttggcttg ccggctcagt tggctgcagc ccttggctat
    21001 gctgcggtat ttggcagtgc caccaatacc tttttagccc cgatatttgt tggattagag
    21061 gtttttggtg caacaaacgc aactgcttac tttatcgtga tagcctttgc ttatatggtg
    21121 agccgaaggc attcaatcta cactaagcaa agggtgacca ctagcatcgc ttcctagtgt
    21181 cttggtcagt tttttggaga aaatagcttt acaagtgggg cttattttgt tacaataggc
    21241 tccgtgtgta atggacgcac aaaaattacg gctaatccgc taagactcgc gcttaagatt
    21301 agtaagataa ggagaataaa caatgaatcc attaattcaa agcttgacag agggtcaact
    21361 tcgtactgat attcctagct tccgtcctgg tgacactgtt cgtgtgcacg caaaggttgt
    21421 cgaaggatct cgtgaacgta tccagatctt tgagggagta gtcatttcac gtaaaagtca
    21481 aggtatctca gagatgtata ctgttcgtaa gatttctagt ggtatcggtg tagagcgtac
    21541 cttcccaatt cacacaccac gtgttgaaaa gattgaggtt gtgcgtcatg gtaaggttcg
    21601 tcgtgctaag ctttactacc tacgtgcctt gcaaggtaag gcagcgcgta tcaaggaaat
    21661 tcgtcgctaa aaagagcata cgagaggttt ttcactgtct tatgaaagga ctgctggagc
    21721 agcagggtct ttgggacaag ctttttttcg caggtatgtg aacctacgct caattcaaga
    21781 catatcaaag gctcattcta tgatagagtg ggctttttga ttgtgatcat gctttagtgc
    21841 ctaaataaat gacagcagcc tgactaatga aaggcttact tgactttgga aatgctcaag
    21901 gcttgcgcta ccagatagaa gctgacatca tgccatagca gtcaagggga agaaggacta
    21961 gattttttgg cgaggtgttg atctgtgacc ctgatgttgt tgggaatatg agagtaattt
    22021 aaaatttcgt cttgcattct acctttttct aggttacaat agacaagtaa cctgattagt
    22081 gaagctaaaa gacgtagcga tgggttctaa aaaagaatga ttctggcgtt tttggctaac
    22141 ctaagctgat agctttgcta ggcagtgtct tagtcatctg gtcagtcctg ctagtttaac
    22201 ggataaaaca agcgcctcct aagcgctagc tgtgggttcg attcccgcgc gggacattaa
    22261 aaacaaagta aaaagagtct gagaaggttt gagctgcccc taattgttag atttttttct
    22321 aactcttgaa gtgtgggtca aagactattt gtctcaggac tctttttaat tggtttttac
    22381 taagctgctt catctagttc ttcagttgct aagttgtttc cttcttctgt atgttggttt
    22441 tcatcaagta gcattcctgt gcggtaatct aatgctgcca aaggtgatac attatccaga
    22501 acaactgagg ttataccata atgatcaacg gattctttgt tgcctcccaa tttgatttgg
    22561 aggagctctc cgttttgatc aattccaacg tactgtaaca ctacttgacg aggaactaat
    22621 tcatcattct gataaatagg agttacctta taatctagcc aaaagttagg gtgtatggct
    22681 aaccaattgt ctagtctatt ttcataataa agcattccta aaggattttt atcactaaaa
    22741 cctgtattaa ggtattttgt catagtaact aaatttttgg gttcatcatt taggccgcta
    22801 aactgataac cgactagatg tccgcgatcc attaaccaag tctttttccc tctagaatta
    22861 atgacttgat agttatgcca gccgggagga ttaaatctaa gcgcttttct tttgagagtt
    22921 ggttcatctt gatctttgag ttgtatgtgt gcataggtgg ctctttgtaa atgatcaaga
    22981 tctcccagag ctatttggta ttttccagta aacggtaaaa ttcctggtat ttcggtagct
    23041 tttgttccca atgatatttc cgttgtatct gggaaggttc taagttttct tgcagattga
    23101 acagagttag ctgtgaaaat agtcagaata gttaacaaaa caattgttag acttttccag
    23161 ttacggcgac gtgatttaga catatcaatg ccctcctttt tttgtttacg agttaagtat
    23221 atcactttta attaaaaaaa cttaaaatta ataaaattat tttaattata atattcatct
    23281 aaattatctt tatttttaat tcaaaaatat aagcaattga ttcacataaa caaattgaga
    23341 cgaacagtag attgtagcta tatcacaggt gagatagtaa tgatcgtgcg aaacaataaa
    23401 ctgatttttc catgcgggat atttgttatc agtgagttga atggaactag cagctattgt
    23461 tttattgtta gtcatctagt gtttttaagg tgcttatttt ctgttacaac agtgatgaca
    23521 acaggttaag ctaagttcga tggagcttgg ttttttattg ttacaagaaa gctcatagat
    23581 ggtgattgca ttcttttatc atatgacaat gtttctattt ttgacaaata ttattgtcaa
    23641 aaagtaaatg atctgttaca ctggagttgg actcatgaaa gaaaaaagta atcagtagga
    23701 taacaataac aaagctattt taagcttata ccattgtgtc aatggattgt tgccggaaat
    23761 gactggtgct ttctgttcaa tcaggagaca gcatttatta ggagtgaagc atggcttata
    23821 ggttgagaaa tcggctcaag gagctacgag ctagagatgg cattaatcag acgcagatgg
    23881 cagcattagc aggtgtttcc aggcagacca ttagcctcat tgagcgaaat gaatacacac
    23941 catctattat tattgcaatg aaaattgcta aagtatttaa tgaaccaatt gaacaagtat
    24001 ttagcttagt ggagggcgag agatgaaagc ttttatgacg gaaaaggaca gtacgttggt
    24061 gagaatactt aagtcattac tgcttggatc agggattggc ttagtgttag gtggccttgt
    24121 tggttttggt ttagctaggt ttaacatatt agaaaatggc tttccgatat cagaagaaga
    24181 caccataact ggaataaagt ggggaatgag accccttgtt atcgtgctta tgctgctgag
    24241 catttatgat atttatcaag ttgtcaaaga atatgctaga tatgtcaagc taagcgatga
    24301 tgaaacagag gagctgtacc gttacattaa tcttaagcat gcctatgctt taggatttag
    24361 cgctatggct atggtcttga atatagtcgt tttttctttg ggatataggg tgcctattgc
    24421 taataatgct agctatcttg gtttgacttt tcctatttac gaggctctga tgcttgtggt
    24481 tattagtgtt ctccatgctt atattttgaa ggtttatact cggattcgcg gggtcaagat
    24541 gacgcttgct cctaccttaa aggaattaaa gcagaatatc ttacaacagg acgaggcaga
    24601 attgcaggct aattatcaaa tgtcttttga ggttgtcatg ggccttagtg gctttatatt
    24661 accaggcatt tacgtaatat tattgctttt atctatgatt tttcaaaggg ttgagctgac
    24721 cggactaatc attactgcta gtattcacct ctatattctg gtgaaatcct ttaaatcagc
    24781 acatgatttt tataggtaag gcgtaaggtt ttacctactc aagaattgtt atacagcaaa
    24841 aaagctttga taagccatta ctggcgatca aagctttttg tgtttgttga aaaagaggct
    24901 tttttgaaag agctgttggc tgagatagct tgtcaaacct acaattgcaa gcggcacaag
    24961 gctaatgaga ggttgtccgg taatttcaat gagaaaaaga ggagcagtaa gaggtatctg
    25021 attaatgatt cccaaaaaga gggtcgctcc aatgacaatg gccaagggaa gtggtacaga
    25081 gagataacct agctgattgc taaggcttgc cagtagcaag ccactagctc ctccaagcat
    25141 catagaagga gcaattttgc ctcctttagc tccagaggca aatactgcat agacagcagc
    25201 tgctttactt agtaagagcg aggcggtata agataggctg acatcatggt gtagcagcag
    25261 gaggagaccg gccttgccat tgcctaaaat ctctgggaaa taaaggctta aacaagcact
    25321 aaagccaaaa gcccctaaga cacgagggat aaaccatcgg ctcttaggct ttgcctttgg
    25381 tgcgttttgg agcagctgct ggtagcaaaa ggccagaaat gctaagatgg gactggcaat
    25441 gatagcccaa aggactgttg tcagttgcca ggcttgtggg agaatgagat actgtatgtc
    25501 ctgatgtccg cttagaacaa gcacactttg aacagcagta aaggcagtta tagctgccgc
    25561 gtaaatgtgt ttaactgagc attttttgac aatagcctcc atgataaaga caatcgtagc
    25621 taatggtgcc tggtaaacag ctccaagggc agctcctgaa gcacaggcta aaagcaatcc
    25681 ttgctctgct gctgatgcgt ttatagcttt attgcaagcg gcagtcagtg ccacagcaac
    25741 ctcacgtgaa gcaccttcac gaccgacagg tgctcccatg gagacggtta ttaattgcag
    25801 ccagccatga caaaattgtg tccaagggct gaaatccttt tgctgactga gtgtttgttg
    25861 gataggctga ataggcttgg cttttttagc aagtagctgc cagccgagac cagcaatagc
    25921 tccagccaac aatagagata aaaaacgcct ttctggagct accgttgcaa tcatggtgct
    25981 aaaagaccca gattggtatc caaagctaat agcctgtatg aaatgaatgg cttgagtgag
    26041 cacgtaagcc accacaccag caatcacacc agctaccacc agttggcccg tccatgttaa
    26101 gaaagtaatc aatcgagtaa tcatatcttt tattatagca gataaaaaga gcctgagact
    26161 actcaggctc caaaatatag ataaatccaa tcttcatgag aagctggact tatagcccat
    26221 aattgtaatc gtcatcagtc atagcttcaa cagtaccaag aaggtagcca ttaccaactt
    26281 gagagaagaa atcgtggttt gacgtgccgg ttgaaatacc attcataacg attgggttga
    26341 catcattggc agtgtctgga aaaagagggt cctgaccaag gttcatcaaa gccttgttag
    26401 cgttgtagcg taggaaggtc atcacttcct cggtccagcc aacctcatca tagagggtct
    26461 tggtgtattg ctcttcattt tcatatagct gatacagcag gtcatacatc cagtcacgaa
    26521 ggctttcttg ctcactctct gatagctcat taaagcccag ctgaaacttg tagccgatat
    26581 aagtgccatg aacggactca tcacgaatga tgagcttaat aatttcagcg acattagcca
    26641 gcttattgtt gcccagataa tagagtggtg taaaaaagcc agaataaaat agaaaggttt
    26701 cgagataagt cgaggctacc tttttttgaa gggcactgcc attttcataa atgtcgttga
    26761 ttatcttagc cttattttga agaaatacgt tgttgttggt ccactcaaaa atgtcttcaa
    26821 tttctttttt ggtgtttagg gtcgaaaaga ttgatgagta ggatttagca tggacagact
    26881 ccataaattg gatattgtta agaactgcct cttcatgcgg ggtgcgcacg tccttgcgaa
    26941 tggcttcgac tcctgactca gactgcatcg tatcaagaag ggttagcccg ccaaagacct
    27001 tacctactaa atccttttca acagcagata atctgcgcca gtcatcaagg tcatttgata
    27061 gtggaatacg tgtatcaagc cagaattgct ccgtcagctt ttcccaggtt gacttgtcaa
    27121 tgacatcttc gatttcattc cagttgattg cttcatagta tgtggtcatg agtttctccg
    27181 gtagattgta atatagggtt aggtatgcta ggaggagagc cttgagtgct ggtctatcat
    27241 taggacaggt gcactgacac atcagctagg ctctgacatt aaggactggt ccacctcact
    27301 gccattcact tggttagatg acacagcttt cacactgatt ggctccgacc tcctcgccat
    27361 catcggtaaa ggtgcggata taatagattg attttatccc tttattaaag gcgtaatgtc
    27421 tcaaaataga taggtcacga gtggtttgct tgctttctgt tttccattcg tagagctcct
    27481 ttggcaattc gctgcgcaaa aagagtgtta acgacagtcc ctgatcaaca tgctttgtag
    27541 cagctgcata gacatcaatc acctttctca tgtccatatc ataggcagat gtgtagtaag
    27601 gaatggtgtc tgtagatagg ccgttggctg ggtaataaat cttgccgatt ttcttttcct
    27661 gacgttcttc gatccgctga gtaatcgggt gaatagaagc agagcagtcg ttgatatagg
    27721 aaattgatcc attaggagca actgccagac ggttttggtg ataaaggcca tctgtcataa
    27781 tcgcttgacg cagcgccttc cagtctgctg cttgcggaat aaagtgatcc ttgaaaaggc
    27841 ttttaaccag ctctgatttt ggcacacatt ctcctgtgat gtactggtca aaataagcac
    27901 cgctagcata tgttgatttt tcaaagccaa caaaggttgt ctgacgctcg cgagcgatct
    27961 gattggattc gacaagcgtc cagtaattca tcagcataaa gtaaatatca gtaaattcga
    28021 tagattctgg gctgccatat tcgatatggt gctgagccaa ataggaatga agccccatag
    28081 ccccaaggcc aaaggtatgt gcttgactgt taccattttt aacagttggg actgcttcga
    28141 tattagagga gtcagtgaca aaggtcaggg cacgtgtcat ggctctgatg gaacgaccaa
    28201 agtcaggtga cgtcatcatg tttaagatat tagttgatcc cagattgcag gaaatatcag
    28261 ttcccatttt gacaaactcc tgcgcatcat taatgagact aggcgtttga acctgtagaa
    28321 tttctgagca taggttgctc atgatgattt taccgtcaat agggtttgac ctgttggcag
    28381 tgtcgatgtt gataacatag ggatagccag attcctgctg gagcttggaa atctctgtct
    28441 ccaaatcacg tgctttgatt tttgttttgg tgatattagg attggcaacc aattcgtcat
    28501 acatgctagt aatatcaatg tagttaaatg gcaggccgta ttctctttca acactataag
    28561 ggctaaagag atacatgtca gcattgtgac gagcaagctc ataaaactta tctggtacag
    28621 taataccaag tgacaatgtc ttgacccgca ccttttcatc tgcattttct tttttggtag
    28681 acaaaaaagc gataatatca gggtgaaaga cgcttaaata caccacacca gccccttgac
    28741 gctgccctag ctggttggaa taagaaaagc tgtcctcaaa tagcttcatt acaggcacaa
    28801 caccagaagc agctccggca tagcccttga ttggagcgcc agcctcacga aggttggata
    28861 ggctaatgcc aacaccaccc ccaatacggg ataattgcaa ggcagaatta atagagcggc
    28921 caatggcatt catatcatct gtcacctgaa ggagaaagca agaaaccagc tcaccacgac
    28981 ggctccgtcc agcatttaaa aaagaaggag tagcaggttg gtaacgctga ttaatcatct
    29041 caatggctaa gtccttagct aatgtttcat caccatcagc aaaataaagg gcattgaaca
    29101 tgacccgatc ctctatgctc tctaagtaga aattgccatc attggttttt agggcatact
    29161 gctgataaaa tttataggcc gccataaatg atttaaagcg aaagccctct gcttgaatgc
    29221 tcttggctag atggctgata aattcaggag aatagttttg gataaaggct gattcaatat
    29281 agtcattgtc tacaagatag gcaatctttt cgttgataga agaaaatgac atggtgttag
    29341 gaataacatt ttcggtaaaa aaagcctcca aagcttcctt gtctttatga agtggaatgc
    29401 tgccatcaac aggacggtta atttcattgt tgaggcgaaa gtaagaaata tcgccaagat
    29461 ctttgagact catatcaatt gttccttgtc tagttaaata atatctttta attttgctgg
    29521 ctgaaaccct gagaatacta tctgctctgt ctcaataaca ggagcagcag taaagccaag
    29581 gctcttaaca tagtccactt tttctggatg ctcatcaata ttaatctctt ggaaagcagc
    29641 tccatgctgt tctaaaaatt tcttagtcat tttgcactgc atgcaattgt gctttgagta
    29701 tactgtaatc attgctcgtc cttccaacta ttagtctttc actcaatttt aggaaaaatc
    29761 aaatgactct aataggatat aaaaaatgtt cctaaaaagc aaacgattta tttcagaata
    29821 gcacaagata ttgtggttgt gtgtgagaat atttctaaat attgtgttat cctctcttat
    29881 cactgataat tgctacaaga ggcttgtagt tcttaaatgc atactaatca ggttggaagg
    29941 cttatttgac attatgaaaa tcatcatgta agaaatattg acaacaaatg aaaatacaag
    30001 aaaactgttt catgattttt tcttgttaga acatttaacc ttgaaaataa aaaagcattg
    30061 tgctataatc acttattgta agggttatca tgtgatagct cgaaaataca caattcaaaa
    30121 ggagaaccat attatggctt caaaagactt tcacattgtt gcagaaacag gtattcatgc
    30181 acgcccagct accttactta ttcaaacagc aagcaaattt gcttcagata ttacacttga
    30241 ctacaaaggt aaagcagtaa atcttaaatc aatcatgggt gttatgagcc ttggtgttgg
    30301 tcaaggtgct gacgtaacaa tcacagcaga aggcgctgat gcagatgacg ctattgcggc
    30361 aatcgaagaa actatgacta aagaaggatt ggcataagac tatgacagaa atgcttaaag
    30421 gaatcgcagc ctctgacggt gttgctgttg ccaaagcata tctgctagtt cagccggatt
    30481 tgtcatttga gactatcaca gtcgaggata caaatgcaga agaagctcgc cttgatgttg
    30541 cactacaagc ttcacaagac gagctttctg ttatccgaga aaaagcagta gaaagcctag
    30601 gcgaagaagc ggcagcagtt tttgatgccc atttaatggt tcttgctgat ccagagatga
    30661 tcagccaaat taaagagact attcgtgcga agcaaacgaa tgctgaaaca ggtctaaaag
    30721 aagtgactga catgttcatc acaatctttg aaggcatgga agacaatcct tatatgcaag
    30781 agcgtgcggc tgatattcga gatgtcgcta agcgcgtctt ggctcattta ttaggtgtta
    30841 agcttccaaa tccagctaca attgatgaag aagcaattgt tattgcacat gatttgactc
    30901 cttcagatac tgcacagctt aacaaacaat ttgtaaaagc atttgtaacg aacattggcg
    30961 gacgtacgag tcattcggct atcatggccc gtacacttga gattgcggct gtgcttggta
    31021 caaatgatat tactaagcgt gtcaaagatg gtgaccttat tgctgttaat ggtatcactg
    31081 gtgaggttat tattgaccca agtgaggagc agattcttgc tttcaaggaa gctggagagg
    31141 cttatgcgaa gcaaaaggct gagtgggctc tgcttaagga cgcacaaact gtcacagcag
    31201 atggcaagta ctttgaatta gcagcaaaca tcggtacacc taaggacgtt gaaggtgtca
    31261 acgataatgg tgctgaggcg gtaggtcttt accgtactga gtttctttat atggattctc
    31321 aggatttccc aaccgaagat gagcaatatg aagcctacaa ggctgttctt gaaggaatga
    31381 acggcaagcc tgttgttgtt cgtacaatgg atatcggtgg ggacaaggag cttccttact
    31441 ttgatttacc aaaggaaatg aacccattcc ttggttttcg tgccttacgc atttcaatct
    31501 ctgaaacagg taatgctatg ttccgcacac aaattcgtgc tttgctgcgt gcttctgtgc
    31561 atggtcaatt gcgtatcatg ttcccgatgg ttgcccttct aaaggaattt cgtgctgcta
    31621 aagtcgtatt tgaagaagaa aaggctagct tgctgtctga gggtgttgcg gttgcagacg
    31681 atattcaggt tggtatcatg attgagatcc cagcagcagc aatgcttgct gaccaatttg
    31741 ccaaggaggt tgacttcttc tcaattggta caaatgacct tatccagtac acaatggcag
    31801 cagaccgcat gaacgagcaa gtgtcatacc tttaccagcc atataaccca tcaatccttc
    31861 gtttgattaa caatgttatc aaagcagctc atgctgaagg taagtgggct ggtatgtgtg
    31921 gtgaaatggc aggtgaccaa caggctgtgc cgcttcttgt tggtatgggg cttgatgaat
    31981 tttcaatgtc agcaacatct gtgcttcgca cacgtagcct gatgaaaaag cttgattcag
    32041 cgaaaatggc agagtatgct catcgtgcac tcacagaatg ctcaactgct gaagaggttc
    32101 ttgagcttgc caaagagtat attacagaag cttaaataga aataacgagg agctggtttt
    32161 gtccggctct tttttactag aaaaatgact aatcagatcc atatgaaagc ttgctttata
    32221 aagtagtttg atgtttcaag ttttatcaga attttcagac tcttcctgta gcgaattgtt
    32281 gaaatatgct aaaaaagtga tagaataata gtaccattat aaaaggagaa aaaagtttgg
    32341 ctaaacaata taaaaattta gtgaatggtg agtggaagct ctctgaaaat gagatcaaga
    32401 tctatgcacc agcaaccggc gaggagttag gtagtgtacc agctatgtct cgtgaagagg
    32461 ttgatcaggt ttatgcgtca gctcgcgctg ctcttgcaga ttggagagcg ctttcttatg
    32521 ttgagcgtac tgcttatttg cacaaggctg ctgatatttt ggtgcgtgat gctgagaaga
    32581 ttggtgctgt tctctcaaaa gaggttgcaa agggttataa ggctgctgtt agtgaggtta
    32641 ttcgtacagc agaaattatt aactatgcag cagaagaagg ccttcgtatg gaaggcgagg
    32701 tccttgaggg tggcagcttt gaggctgcta gtaagaaaaa gattgcgatc gtacgtcgtg
    32761 agccagtggg acttgtgctt gcgatttcac ccttcaatta tccgattaac ctagcaggct
    32821 caaagattgc tccagccctt attgcaggaa atgtcgtggt tcttaagccg ccgacacaag
    32881 gctctatttc tggcttgctc ttagcagagg tatttgcaga agcaggtctt cctgctggag
    32941 tctttaatac catcactgga cgcggctcag ttattggtga ttacatcgtt gagcatgagg
    33001 ctgtaaactt tatcaacttt actggctcaa cgccaattgg agagcgaatt ggtaaattag
    33061 ccggcatgcg tccgattatg cttgagcttg gtggtaagga ttcagcgatt gtcttagaag
    33121 atgctgatat tgccttagct gctaaaaaca ttgttgcagg tgcctttggc tactcaggtc
    33181 aacgctgtac agcagttaag cgtgtgcttg ttatggaaag cgttgcagac cagctggtag
    33241 cagagattaa gggcttagtt gagaaattac ttatcggtat gccagaggac aatgctgaca
    33301 tcacaccatt gattgatacc aaagcggcag attttgttga aggtctggtt aatgatgcag
    33361 cagacaaggg agcacaggcg cttactgaaa tcaagcgtga cggtaattta atttgtccta
    33421 tcttgtttga tagagtaaca actgatatgc gcttggcttg ggaggagcca tttggtccgg
    33481 tgctgccagt gattcgtgta agctctgtag aagaggcaat cagcatttca aatcaatctg
    33541 aatacggttt gcaagcgtct atctttacga ctaattttcc acaggccttt gctattgctg
    33601 agaagcttga ggttggtaca gtacacatta acaacaaaac ccaacgtggt acagataatt
    33661 tcccattcct aggggctaag aaatcaggag ctggtgttca aggggtcaaa tattcaattg
    33721 aggcaatgac aagtctcaaa tcagtcgtat ttgatattca ataacaaaaa agctagggta
    33781 tcttagtttg aaagcagttg cacatttgtg cggctgtttt atttgtgtct ctagttttaa
    33841 cagctagcta tgcaagaagg tgagttgtcc caacctcaaa gatgagatct aaatatttaa
    33901 tgattttggg gtcgtaaaaa agtttagagt gttttgatct ccttaagatg tgagtgtaca
    33961 aagtctcgcc aacagccagc aggactagcc attgaggtca aggaagctgc taaaatagct
    34021 gatggttcaa aagcttggtg aaaggcttaa tatctatcat tgctattttg agggctttcc
    34081 attataatat gaatactaga gctacttgtc ggtctgcctc ttgagctgtg agatagctgt
    34141 tggatttagt tgtctccttg tccacaaaag gcttagaggc aaaggctgtg gctatgcttc
    34201 ttgcttcttt tagtgaagtg tatgagatct tatgaaaact catataggct ttggtatctt
    34261 tgcaagagga ctaatggctt gctttacttg ccttgataga gggctgggat tgaggggtga
    34321 tgacctgcgg tggtcatctc tagagctcct tgcttctttt tttatgtaga ctaatggttt
    34381 agactgctag cttccttgtt tagaaagtag gacatcatgt tacccaagag aaaattaatt
    34441 gatcaacgtc ttgattatgc cattattttt cctgtttttt gtttgctaat atttggtctg
    34501 gtatctgtat atgtggcagc aagtcatgat tttccgcaaa gcctcgccac tgttatgctt
    34561 caacaggttc tctggatcct tcttggagct gtgattgcct ttaccctaat gttttttagc
    34621 acagagattc tgtggaaatt aacacctgtc ttttatcttt tgggtgtgct attaatggtt
    34681 ctgccactca tcttttttag ccctcggctg gtagctgcta caggggcgaa aaattggatt
    34741 acgattggct caacgacctt gtttcaacca tcagaattta tgaaaatatc ctacattctg
    34801 gcaatgtctt ggttaacggt ctggtttaag agaaagcagg agagaagtcg gtttttagat
    34861 gattggaagc tcttgggctt ataccttgtc ttgacgttgc cggtcatggt cctgctagca
    34921 ctgcaaaagg acttaggaac agctatggtt tttttagcca tcttagctgg gattatctta
    34981 atttcaggaa tttcttggtg gcttatttta ccagctttgg tactagtctt tttactggtt
    35041 tcagcttttt tctttgtttt tttgttgcca gagggaaaag aattcctttt aaaaatggga
    35101 atggatacct accaattgaa tcgtatttca gcttggctga caccgtttga tttctcagat
    35161 accattgcct atcagcagac gcaaagtatg atttcgattg ggagtggtgg cttttttggt
    35221 aagggcttta atcagcttga gctgtcagta ccagtcagag aaagtgatat gatttttaca
    35281 gtgatcgctg aaaattttgg ctttcttggt gcagctagct tactgatctt gtatttaata
    35341 ctgatttacc gcatgcttag ggtgaccttt gcatcgaata acctttttta tacctacatt
    35401 tcaaccggct ttatcatgat gatactattt catatttttg aaaacattgg cgcagcagtt
    35461 ggtctgctac ctttgaccgg tattcccctt ccctttattt ctcagggcgg ctcttccttg
    35521 atttcaaatc tgattggggt cggcctgatc ctatcaatga actatcagca cgtccttgct
    35581 catgaaaagc aaagcgagca tgagcttagc agaagctcac gttatgttta agaggcatgt
    35641 ttggtccttg ttcggttaga atgagctgcc aatcagccct tttttatttg cttaatcgct
    35701 ataaaaataa agaaaaatat gttataatta aggttatgaa ttatcatgat tatatttggg
    35761 atttgggcgg cactctcttg gataactatg aaatttctac ccaggctttt attgagacgc
    35821 tgcatttttt taagctgtct gcaagccacg atgccgttta tcaaaggctt aagaaatcaa
    35881 cagcaaccgc cattcaagta tttgctccca acgaaccgca atttttacaa tattacaaag
    35941 cgaatgaggc taagaaatta gccaatccta tttggtgcct aggtgcaaag gacattctaa
    36001 agaggattgt ggcatcaggc tcgcgtaatt ttttaatatc ccatcgtgat catcaggtca
    36061 atgatttgct ggagcaggct gggcttttgg gctattttac cgaggttgtt accgcctcaa
    36121 atggctttgc cagaaagcct aaccctgaga gcttacttta tttgaaggaa aagtacctga
    36181 tcagcaaggg cttagtgatt ggtgatcgca gacttgatat agaagcagga caagcagcag
    36241 gctttgacac cctgcttgtt gatggtagaa aaaacctatt ggagatagta gattagatgg
    36301 ttgaagaaaa taaacaatta gaagacaagg ctcaagagta tgacgctagc cagattcagg
    36361 tcttagaggg gttagaagcc gttcgcatgc gtcctggaat gtatattggc tcaactgcca
    36421 aggaaggctt acatcaccta gtttgggaga ttgttgataa ttctatcgat gaagccttgg
    36481 caggctttgc cagtcatatt caggttttta ttgaggcaga taattcgatt accgttattg
    36541 atgatggacg tggtatccca gttgatattc aagctaagac aggccggcct gctgtagaga
    36601 cagtttttac agttttgcat gccggtggaa aatttggcgg tggtggctac aaggtttctg
    36661 gaggacttca tggtgttggc tcctcggttg ttaatgcctt atccacacag cttgatgttc
    36721 gtgtctataa aaatgggcat atccactatc aggagtttag gcgtggtgct gtagttgatg
    36781 atttggctat cattggaacg actgatgtta cgggaacaac agtgcatttc acacctgatc
    36841 cagagatctt tacagaaaca acagaatttg actaccaggt cctggcaaag cgtattcaag
    36901 agctggcctt tcttaatcgt ggcttaaaaa tctcaattac agataaacga gctggtcttg
    36961 aaagagaaga gcatttccat tacgagggtg gtattggctc ttatgttgcc tttttaaatg
    37021 acaaaaagga cgtcatcttc gatactccga tttattctga tggtgagctg gaggggataa
    37081 cagttgaggt ggcgatgcag tacactacag gttaccatga gactgttatg agctttgcca
    37141 acaatattca cacacatgag ggtggtaccc atgagcaggg ctttagaaca gctctgacgc
    37201 gcgtgattaa tgactatgct aagaaggcta agattctcaa ggaaaacgag gataatctga
    37261 caggtgagga cgtccgcgag ggcttgactg ctgttatttc tgtcaagcac ccaaatccac
    37321 aatttgaagg gcaaacaaag acaaagttag gaaattctga ggttgttaag attaccaatc
    37381 gcttgtttag cgaagctctt cagcgctttc tactagagaa tccgcaggtt gcccgtaaga
    37441 ttgttgaaaa ggggattcta gcctctaagg ctcgcattgc tgccaagaga gcgcgtgaag
    37501 taacccgcaa aaaatcaggc ctagagattt ccaatttgcc agggaagctg gctgactgct
    37561 cctcaaatga tgctagtcaa aatgagcttt ttatcgtgga gggggattcg gctggtggat
    37621 cagcgaagtc aggtcgcaat cgtgagtttc aggctattct gcctattcgt ggtaaaattt
    37681 taaacgttga aaaagcaacg atggataaaa tccttgctaa cgaagaaatc agaagcctct
    37741 ttactgctat ggggacaggc tttggagcgg agtttgatgt ttctagagct cgctatcaaa
    37801 agctggtcat catgactgat gcagatgtcg atggagctca tatcagaacg cttttgttaa
    37861 cgttgattta tcgcttcatg cgaccagtat tagaggctgg ctatgtttac attgctcagc
    37921 caccgattta tggtgttaag gttggcagcg agattaagga atacattcaa ccgggagtca
    37981 accaagaaga ggagctaaag gctgctcttg aaagacatag cacaggacgc tcaaggccga
    38041 ctattcaacg ctataagggc ctaggagaga tggacgatca ccagctttgg gaaacaacaa
    38101 tggaccctga taatcgtcta atggcacgtg tgaccgtaga tgatgcggca gaggctgatc
    38161 ggatttttga catgctgatg ggcgatcgtg ttgagccaag gcgtgaattt attgaggaaa
    38221 atgcggtcta tagtacgctt gacatttagt caaatatatt ttgaaaagca cctaaaagta
    38281 tgttataatc gtaacgttat agtgtatttt tgataatata ataaaaggcg attcttgcta
    38341 gttgttccta ctgaaccggc agttgatcaa tcgcatctaa ataataagga gattaagatg
    38401 tcaagcggaa ttatcttgct gattgtggcc atagtcttac tagtgattat tgcttattta
    38461 gtgggtgtta ttatacgcaa gcgtaatgac acattaatta ccagtctaga agaacgaaaa
    38521 caagctttat ttggccttcc tgttaatgac gaaatcgagg aagtcaagtc tcttcacttg
    38581 attggtcaaa gccagacctc atttcgtgaa tggaatcaaa agtgggttga tttgacccta
    38641 aataccttta ccgatattga aaagcatatc tttgaggctg agcacttaaa tgacaccttt
    38701 aatttcattc gtgccaagca tgagattaat agcgttgaga gtcaattgaa tctcgttgaa
    38761 gaggatatta ccgctattcg tgaagcactt ggcatattaa aggagcagga agaaaaaaac
    38821 agcgcgcgtg ttactcatgc actagatttg tacgaaaagt tgcaggcttc cgttgctgaa
    38881 aatgaagata atttcggatc aacaatggcc gaaattgaaa agcaaatgaa gaatattgaa
    38941 gcagagtttt cacaatttgt tgcccttaat tcatcaggtg accctgttga agcagcggag
    39001 gttttggata aggctgagga gcatacgatt gccttggggc aaattacaga gcagatccct
    39061 gctattgtag caaagcttga agatgatttt ccggatcaat tggacgatct ggagacaggc
    39121 tatcgtcgtt tgctggagga aaattatcac ttcccagaaa aaaatattga agcccgcttt
    39181 caagagattc gtgagtctat tcgtgccaat tcatcagagc tggttaccct tgatttggac
    39241 cgagctagag atgaaaatac tcacattcaa gagcgtatcg actcactgta tgagctcttt
    39301 gagcgtgaga ttgcagccta caaggtggtt gctaaaaata gcaaaatatt accaagatac
    39361 ctggctcacg ccaagcacaa caacgagcag ttgaagcatg agattgctcg tctatcacgt
    39421 aagtatatct tgagtgaaaa tgaaggctta aatatcaagg cctttgacaa agacctcaaa
    39481 gatatcgaag acaatgtcct tgagattgct gaagcctttg atcagcagga aaagccattt
    39541 tcagagctac agctgattct tgatcgtagt atcaagacgt tggcttctgt agagtctggt
    39601 cagatggacg tctttgctgc tgttaaagac attgaaaaga ttgagtcaca ggctcgccag
    39661 cacttagaaa tctacgtcac acagcttcac atgattaagc gttatatgga aaagcgcaat
    39721 ttaccgggaa ttccacagga ttttctgagt accttcttta ccactagttc gcagctagaa
    39781 gcattgatgg acgaactaag tagaggacgt atcaacattg aagcggtgtc ccgtctgtct
    39841 gaggtggcaa cagctgctat tgctaatcta gaagagctaa cctaccaagt ggttcagcat
    39901 gctaccttga cagagcagct gctccagtac tctaaccgtt atcgttcctt tgaagctggc
    39961 gtgcaaaata gctttgagca tgccttgaaa ttgttcgagg tggacaatga ctatcaggca
    40021 tcatttgatg agatttccta tgccttggag acagtcgagc caggagtgac agagcgtttt
    40081 gtcaattcct atgagaagac acgtgaacgt atccgcttct aatgtgacaa gggttgatac
    40141 tttatattac gaaaaagctt gaaaaagcag tccatgctgg gctatgcttt ttcaagcttt
    40201 ttgaatggtc aggctatggc ctccttgagc tatacccaaa aagctggttc aagccagtca
    40261 gtagagatag acaaggcctt agtgctattg ggctgttgct acatgagata ttttgtaata
    40321 aaatcagacg attatccatt taattaaaaa aaaaaaaaaa cgaaactgcg gaggaaacct
    40381 gacgagtaac tatttatggc tatcaatcag catgttacac tctttttgga aggcctagca
    40441 atcactgact gtgaggttaa ccaaagaaaa taagatgtta aggagaatat caatgaaaat
    40501 aactaaagca ttgtgtgtag caggtgctgt tgcagtccta gccttggcac caatcagctc
    40561 aagtcctgca ccaacacaga ctgtatttgc tgctacacgt ggtactgaag agtactgtca
    40621 taatgggtgg tgcagttttc ttgatgaaca tggtgagtgg aacacgaaac gtgagggcga
    40681 atctaatagt cccctacagc gaggttcatg gtgggattgg atttcttatt ggtctggtta
    40741 tatatggtat tctgtatata actggtttag gtaacctctc aacgccactg ctaccatact
    40801 gataaatccc ttagactatt ctaagggatt tttactgcaa aaagcacata gggacaaggc
    40861 aatacaagct ccagcctgtt cttagctccc tataccggta aggatcataa cactcagaac
    40921 tccggcagat gattgcagga gctattggag agtgaggact agtgaaagag cctctgccag
    40981 agggatttgc ccttagtctt tgtttgttca gcaggcttat tgtcagaggg cttgtctagt
    41041 atagccttga gattggtttc ctctttggtg atggcatgat cactatgaat gatcagagca
    41101 aaaggagaga cagctccttt ctcatctaca atagtggcag atagagcgtt ttgttgggcc
    41161 aatttcatat agtacatttg ataagcagag ccgaattcag aggataattt gaatgacaag
    41221 gggaaataag cctctttgag gtgaggcagc tgggctgtga tgtagccttt agccttttca
    41281 tgatcaacct ctgtcaaggg aagcgctaag acaatccttt cagcataggt ccctaaataa
    41341 tagcgttgtt ggtcggggtc aaatcggttt tctcctgaag ctccctttaa gagtcttgta
    41401 tctaatgaat ccatacaatc ctttcaagca tgtgatactg tcattatact attaactgcg
    41461 ccaaatacca atgataaagc atttactagg tatttgatcg gcttttggaa gaagatgaaa
    41521 tcaaagaaaa acagcatgaa aacaactctc ttatttcatg aaattagttt ttaagttgct
    41581 taagacccta gtttgtggta ttattaacat gtaaaatatt aaaactcata aggagagtat
    41641 tataatgtca attattactg atgtttacgc tcgcgaagtc cttgactcac gcggtaaccc
    41701 aacacttgaa gtggaagttt atactgaatc aggtgctttc ggacgtggta tggttccttc
    41761 aggagcttct actggtgagc atgaagcagt agaacttcgt gatggcgaca aatctcgtta
    41821 ccttggtctt ggtactcaaa aggcagttga caacgttaac aacattatcg ctgaagcgat
    41881 cattggttat gatgttcgcg atcaacaagc tattgacaga gccatgatcg ctcttgacgg
    41941 tactccaaac aaaggtaagc ttggtgctaa tgctattctt ggtgtgtcta tcgctgtagc
    42001 gcgtgctgct gctgactacc ttgaggtgcc actttacact taccttggag gattcaatac
    42061 taaggttctt ccaactccta tgatgaatat tatcaacggt ggttctcact cagacgctcc
    42121 aattgctttc caagagttca tgattatgcc agttggtgca cctaccttca aagaaggtct
    42181 tcgttggggt gctgaggtat tccatgctct taagaaaatc cttaaagcgc gtggacttgt
    42241 tactgctgtt ggtgacgaag gtggatttgc tcctaaattt gaaggaactg aagatggtgt
    42301 agaaacaatc cttaaggcta tcgaagctgc tggctatgaa gctggtgaaa atggtatcat
    42361 gattggtttt gactgtgcgt catcagaatt ctacgataaa gagcgcaaag tctacgacta
    42421 cactaagttt gaaggtgaag gcgctgctgt tcgtacatct gcagagcaaa ttgactacct
    42481 tgaagaattg gttaacaaat acccaattat cacaatcgaa gacggtatgg acgaaaatga
    42541 ctgggaaggc tggaaagcac ttactgagcg cctaggcaaa cgtgttcaat tggttggtga
    42601 tgacttcttc gttacaaaca ctgaatacct tgctcgtggt atcaaagaag gtgcagctaa
    42661 ctcaatcctt atcaaggtta accaaatcgg tactttgact gaaacctttg aagctatcga
    42721 aatggctaag gaagctggct acactgctgt tgtatcacac cgctcaggtg aaactgaaga
    42781 ttcaacaatc gctgacatcg cagtggcaac aaacgctggc caaatcaaaa caggttcatt
    42841 gtcacgtact gaccgtatcg ctaaatacaa ccaattgctt cgcatcgaag atcaacttgg
    42901 tgaagttgca caatacaaag ggatcaaatc attctacaac cttaaaaaat aatttgattt
    42961 tagattaaaa ggttgacaag ccttgatttt aaagcattct aggactgtcc tagagtgctt
    43021 ttagttttag cttcatgtca actgtagtgg gtgactgata gctaagcacg agaggagacg
    43081 aaggtcgcct tctctttttc aatcggataa ggctagggaa tccccaaatg tcgatgaagg
    43141 gaattttaga aggtttctgg aagtcgtata tgatttgttt ccctttgcag tgtctacacc
    43201 taggagactg atagtccagt gtagcgctga cttcgatatg agtatcgtgc tggatagtct
    43261 tattcaaggt gatattttga tctttgattc cgatgagtag tgtggtatga tgaatctgtt
    43321 ccataagaca ctttctaatg atggtctggt cgcttttcat gataagcctt atggaacttt
    43381 ttgggtactc aaaaagccct ataatcttca taatgaattt acccattaca gaaattatag
    43441 agccaatatt tagaggattt tagcctattg gtagattgac agtttcttaa gattgtgtta
    43501 caatgtaaca caaagaaacg aggtaaacga ctatgagtac agttactatc agattaaatc
    43561 aagaagaaga aatatttttc aaaagttacg cccaactcac agggcaaagt ttatcaagtc
    43621 tatttaaaaa agcccttgag cgggatattg aagatgagta tgatttaaaa atctatcatc
    43681 aagcctatgc tgaatataaa gcagaccctg agacaattag ccatgctgat tttaagaaag
    43741 agctaggctt ataacatgta ccgtatagag tattctaaaa aggctcaaaa gcagattaag
    43801 aaagtagata agcaaattca gaggttgcta tttgcttgga ttgataagta tttagaggga
    43861 acagataacc cacgcgcaaa tggcaaaggt ttgaccggaa atcatgctaa tgagtggcgt
    43921 tatcgtattg gtgattatag gcttatttgt gatattcaag atgataagat ggttgtttta
    43981 gcgcttgagt ttgggcatcg taaagatatt tactaacgtt gaggaagtaa gatggtcaaa
    44041 aataatgcaa ttggtagcaa ctggaaagat gtaagagctg agttattcag caaggaagaa
    44101 ttttagaaag tgatgctcgt attgctatta tggacaagta tagttaaaaa gtgtgcgttt
    44161 ttaatctgta tgatgaagta attgataaag taacaggtca aaaggctatc attgtctgta
    44221 ttgctaataa attggtagat gattgttatt taatcgaacc gctaaaccat tcttacttac
    44281 cagattggcg tgagataaat cagttaattc gatataaaaa ttagcacctt atcgggtgct
    44341 aattccttgc ctgctgaact cataatttaa tacctttttt actaccccat atgtttcccc
    44401 taattatgtg tacttgctag atataaggtt aattgggata gaattttgaa taaagttgtt
    44461 gtattttgta atagtgattg atattgggat aaccttaaaa aaataatttg attttagatt
    44521 aaaaggttta caagctttga ttttaaagca ttctaggact gtcctagaat gcttttagtt
    44581 ttgataagca caatccgctg ttgactgtat aaaccgtata tgatacaaaa taagagcttg
    44641 tagcagtgaa gccactaact ctagtgctgt gggctcaacc ttgattgatg aatcccttgc
    44701 ttttaatgcg tttatgaagc agtggcgtat cagtctagct cgttgtggaa agcaattaac
    44761 tagagaagaa ttactatcct caatcaatat gctgacagcc gcagggattt gtgagtttga
    44821 tttgctgtgg cagcgtcttg ctcctaaggg gtgtcagcgt cccaaatgga gccatcagct
    44881 ggagaggctc tttgcggata caaagccttg tctacaggtc ttgtctgaga cttatcagct
    44941 tgggattatt gctaatcagg caaagggtct aaaagagcgc ttagagaggt ttgggattag
    45001 tcattatttt gcccttatga tatcttcttc tgatgtgggg ctacaaaagc ctgatcttgc
    45061 tctgtttcgc tatgcacttg atcaagcagg cgtattagcg cgtgatgctg tttatattgg
    45121 ggatcgtgtt gacaatgata ttattcctgc taaggcattg ggaatgagag ctgtcaggat
    45181 tcatcaaggg cttgctgcgt ccagtccaga tgataggctt tatcctagtg atgtccatat
    45241 tagcaaactt agtgacctgt tagaatgctt ttaaccagtc tttagcttga actagctttt
    45301 ctttgtggtc tttctgggtg aatggcagca agctttggag tcatgttatg gctagacctt
    45361 ggatctaagg gcgctgagcg tctcatatga tgaggccgat caagtagtct ccttgacaag
    45421 tagattattg tttggtgctt ataggtggct ttaggtgatg actggttttg cctcaactaa
    45481 ggctcgctat tgctatctgg ggtatcttct gactttttta atgtgctctt atctggttgg
    45541 attagacctg ctccttgctt gaggaaagct gtttttaacg ctgatgagtc tgggaaatgg
    45601 tgagattggt gttggctttt actagttttt ttgcgtttac ttgggctaac tttatatgag
    45661 aaaaaaagaa aaatatttat tttatctgtt atttttgtta caataagcgt gtaaactaag
    45721 atgcattaaa aaggagtttt tatgtcgaat aagaaatttt ttacttatgc ttcattattg
    45781 gcattaatcg ctgttcctac tgtggttgaa gaggtgactg cacagccttc agctcagctt
    45841 gtttatgcag atgagctaag gctatcacca agtaccgact catctccagt aacaaagacc
    45901 gatgaggctg atcagccagt tgctcaatct gtttctgcga cagaaccagt agaggctctt
    45961 gttattgcgg ataaagaaag cgctttaaat cctgctgttc tagctgatgc cgatggaagt
    46021 cagccgattg cagtggttag agctggtcaa gagggtcagc cttataccgt tactggcaaa
    46081 atcatcagtg ctgttaatgg ctggggtggt catggctttt atatccagga cagtcaggga
    46141 tcaggtcttt acatttatcc aggaagtgct ttggggtacg tgactggtga tgtggtgcag
    46201 ctgacaggaa cactgactac ttacaagggt gagcttcagc ttaaaacgat tacaaagcat
    46261 cataagatta atggcgaatt accaacacct attgctgagg taaccattcc ggagctagaa
    46321 aaagcaagcc cgtctaccct ggtgaagctt tcaaatgtga ctgttggaga catttcatca
    46381 gataagcacg aaacctcctc ttttaaggtc agcgatacag ctggcaatag tgttgcggtg
    46441 cgtcttgata atcgtacagg tgttaagacc tctgacttac tctctaaaat tggcaagggt
    46501 gatgtgatta atctgacagc tattcactca acctttgatg ggaagctcca gctcaagccc
    46561 tttagccttg agcaatttga ggtagtaaag aaggttgttc gagaagaaga ggtgactcct
    46621 cttggtcgag tggttaaaat cggccaaatt caaggtgcca gccacacctc accgctcttg
    46681 aatcaagctg taacagtaaa agaggtggtg gtgacctatc ttgatgatgc aactcatttc
    46741 tatgtgcaag atattaatgg tgacaacgat aaggcgacct cagacggtat tcgtgtcttt
    46801 gctcaaaatg ctcaggtgca ggctggtgat gtgctgacca tttccggaac agtggaggag
    46861 ttctttggca aaggctacga tgaccgtaag cagacggatc tgaccattac gcaaatcaag
    46921 gcatctaagg tcactaaaac agggactgct caggtaccag ctccgcttgt gctaggtaag
    46981 gatcgtgttg ctccagctaa tatcattgat aatgatggct ttagtgtttt tgatccagaa
    47041 gaggacgcta ttgatttttg ggaatccttg gagggaatgc ttgttgccgt tgataatgcc
    47101 aagattttag ggccgatgtc tcataaggaa atttatgtgt taccagggtc atcaactcga
    47161 gtgctgacta actcaggtgg tattttactt cctgagacag gctataatac agacctgatt
    47221 cctgttctct ttaaaaaagg aaagcaaacc atcaaagctg gtgattccta tcagggacga
    47281 cttgcaggtc cggtatcata tagctatggt aattataagg tgtttgtcga tgacagcagt
    47341 cgtatgccag tcttggttga tggtcagctg aagcctgaaa agacacacat caagaaggac
    47401 cttagcaagc taagcattgc ctcatacaac attgaaaact tctcagcaaa cccatcatca
    47461 acaaaagacg agaaggtaag gcgcattgca gaatccttca tctatgacct aaatgctcct
    47521 gatattattg gtctcatcga ggttcaggac aataatggac ctactgatga tggcacaaca
    47581 gatgcaacac aaagcgctca gcgcttgatt gatgccatca aggccttagg tggaccagct
    47641 tatcaatatg tggatattgc tccggaaaat aacgctgatg gtgggcagcc gggcagtaat
    47701 attcggacag gcttcctgta tcagccagga cgtgtcagcc tttctgataa gcctagaggt
    47761 ggtgttaatg atgcggtgaa atgggtaaat ggtgagctaa gcttgagtgt tggacgtatt
    47821 gacccaacaa atcctgcttg gaatagtgtt agaaaatcat tggctgctga gtttattttc
    47881 caaggccaca aggttgtggt ggttgccaat catttgaatt ccaaacgagg cgacaattca
    47941 ttatatggac gtgttcagcc ggtaaccttt aaatcagagg aaagacgtca tgtcttagca
    48001 aggcttttga gccaatttac taaggaaggt gctagtcagc aggctaatat cgttatgttg
    48061 ggtgacttta acgattatga gtttacgaag accattaagc tgattgaaga aggagatatg
    48121 gcaaatttgg tgagcaggca tgagctttct gaccgttatt cttacttcta tagaggaaat
    48181 aaccaaacgc ttgataacat gcttgtttca cgcaatttgc ttggtcgcta cgagtttgac
    48241 atggttcatg tgaattcacc atttatggaa gcgcatggac gtgcttctga tcatgatccg
    48301 ttgcttcttc agctctcctt tggaaaagac aagccagcag caccatcaga tcagccaaag
    48361 aaaacaccag caccagctgc gacaactcaa gcctctaagg caggacgtgc acagctattg
    48421 ccaaaaacag gtgataagac agcgcttatg gtaagtattt taggcttaac agctgtcttt
    48481 agctccttta gcctgtttag gaaatgtcag gaaaggaagt aaaggatttc tttggggtag
    48541 gccagcagct gagcggctac tgcgttttgt ctgctggtgc tatataggtg gttgaagcga
    48601 gcgaagagag gtatgcttcc taggatcata gcacaatatc ttatgcttat aaacgaacac
    48661 aatgctcctt atgagcattc aaaacctata ctcaaaagga atataacagc tgagttaaga
    48721 gggattgctt ttgacagatt gtggtaaaaa aagggatctt gaggaattgg ctagtgatct
    48781 agctgccaaa atgcgatgtc ttgtttgact atttttccct attgggatat aatgacaata
    48841 gaaaaagggt agttgtttgc gcaactaccc tgtgcagaac cgtttaagac ggtggcagaa
    48901 tgaaagttaa aaaataatcg tcgacctacc aaagttcaga cggttatttt ttattgttta
    48961 atatgacgat tgcaacgact aagctgatta aggtaagtaa gaaactacca aaagccagca
    49021 tgagttgaag ggcctcgtaa gtagacaata aaacgctcct ttcagttgga ttttgatgca
    49081 ttgcccatag gcatcaccac ctttcagaaa tcagagccac cgtcttagct tttctgtaaa
    49141 gaacattata tcataatcac atgagaaagc cgttagattt taaactgatc aggcggcttt
    49201 ttggtgtttt gctgtctttt agtggaatcg cctaagcttt gctgtatagt atgggatttt
    49261 atgctttttg taagggctta ggctgctatg gcagggtcca tgtcctttgt caatagctta
    49321 gttttatggt acaatgtagg cgttgcctag caacccttgg tgcttagttc cctttcacca
    49381 agcatattac aaacgtggcg gagctgttta tgctctagtc tgacgtcaaa ggagaaacac
    49441 atgacaagtt ttactgttcg tgactatgtt tacattgctc tagtggctgc cctttatgtg
    49501 gttttgacaa tcactccacc tttgaatgct atttcctatg gcatgtatca atttcgggtt
    49561 gccgagatga tgaatttttt ggctttttac cataaaaagt atatcattgc ggtgaccttg
    49621 ggctgtatga ttgctaattt ttatagcttt ggcttgattg atgttttggt gggtggaggc
    49681 tcaacgctca tttttgttag cttaggtgtc gctttattta agcaatacca agaggaatat
    49741 ctcttaaatg gcttgctgaa taaggccttt gtttatttct cactattttt tgcgacttct
    49801 atgatcaccg ttgcgattga gctttacttc tttggagcac catttttcct aacttggttt
    49861 accactgctg taggggaatt tgcttcactt atcattggct ctatgatcat tgatcgctta
    49921 tcaaaacgca ttaatttacg acaataatag taacatgtag ccttccgttt ttgggaggct
    49981 ttttatgatt ttcttctagc taggcaatag cttatttgct atgttttgtg ataaaataag
    50041 actatgaaaa aacgcataag agaattgact gatctgttaa atcaataccg tcaggagtat
    50101 tacaccaatg acgctccttc tgtatctgat agtgagtatg ataagcttta tcgtgagctt
    50161 gtagagctgg agcagaccta tccagcctat atcctaaagg acagccccac acagctggtg
    50221 ggcagtacga ttttgacagg atttcagaaa tatcagcacc agtatccgct ctttagtttg
    50281 caggatgctt tttcacgtga agagcttaac gcctttgatc agcggatcaa atcagccttt
    50341 cctgaggctg aataccttgc tgagctaaaa attgatggct tgtccatttc gctggtttat
    50401 gaggctggtg ttctaaaggt tggagcgaca cgtggcgatg ggactattgg cgagaatatc
    50461 actgaaaaca ttaagaatat taaggatatt cccaaacggc taagtcaagc acttgatgtg
    50521 acgatacggg gggaggccta tatgtcgcgt caggccttta agacgatcaa tgaagagcgt
    50581 caggaaaatg gtgagccaga atttgccaat ccaagaaatg cagcggcagg aaccttgagg
    50641 cagctggata ctaggattgt tgccaagcga cagctagcaa cctttttgta tcaggaggta
    50701 ggcctagaaa ctgctgatag ccagcaaaag accttggagc gcttggccga tttaggcttt
    50761 tcggtcaata gccactatct gctgtcctca tcgatgaatg acatttggga ctttatccag
    50821 agcattgaag ctagtagaga agagctacct tatgagattg atggtgtggt ggtcaaggtt
    50881 aatcagttgg cgatccaaga ggaacttggc tttaccgtca aggcaccacg ctgggctatt
    50941 gcttataagt ttccagcaga agaaaaggaa gctgagattg tatctgtgga ttggacggtt
    51001 ggccgaacag gtgtggtcac accaacagct aatttgaccc ctgtgcagct ggcaggcacc
    51061 actgtcagtc gagcgacctt gcataatgtt gattatatcg cagaaaagga tattcgcatt
    51121 ggggatacgg tggtggtgta taaggctgga gatattattc cagctgtttt gcgggtggtt
    51181 gaggctaagc gtagggatca ggctccaatg cccattccta cagcctgtcc ttcctgccag
    51241 agtcagctgg tgcattttga ggacgaggta gctttgcgtt gcattaaccc cttgtgtccg
    51301 agcttggttc aacggagctt ggagcatttt gccagtcgtc aggcgatgaa tatcgctggt
    51361 cttggtccag cggttgttga aaagctttat tctgctggcc tggtgcatga tgtggcagat
    51421 atttaccgac taagcttgga ggatttgctg acgctagatg gtatcaagga aaagtcggct
    51481 gaaaagctct tggcagctat tgaacaatca aaggcaaact cagctgaaaa gctcttgttt
    51541 ggacttggta ttcgtcatat tggcgcaaag gctagtcgtc tgatattaga ggcttacggt
    51601 gatttagagg cgctgttagc tgtaaccgct gaagagctcg ctcagattga cgggcttggt
    51661 ctagtgatcg gacaatccct ggtgcagtat tttcagcaag agcaagccgc tcagctgcta
    51721 gctgaattaa aatcagctgg ggttaatctg gcttatttag gccaaaggcc tgatcaacag
    51781 gctgcgctgt ttggtttaac ggtggtattg acaggaaaat tagaaaagct aaaccgtacc
    51841 caagccatgg aaaagctaga gcagcttggt gctaaggtaa caggaagcgt ttctaaaaaa
    51901 acagatttag tggttgctgg cagcgaggca ggctctaagc tggctaaggc ccagcagctg
    51961 ggtatcagaa ttgaagatga ggattggttg ctcaatcttt agtgaggtaa taacatgaaa
    52021 aaacaaatga gggctcgtct gatttacaat ccaacctctg gtcaagaaat catgaaaaaa
    52081 aacgttgcag aggtgctgga tattttggaa ggctttggct atgaaacctc tgcctttcaa
    52141 acgacagcag ctaagcactc agccttaaag gaagcaagaa gggcagctaa agcaggcttt
    52201 gacctcttga ttgctgctgg tggagatggt acgatcaacg aagtagtcaa tggcattgct
    52261 cccctagaga aaagacctaa gatggcgatt attccagcag gaaccaccaa tgattttgct
    52321 agggccttaa aggtaccaag aggcaatccc gttgaggccg ctaagctgat tggtaaaaat
    52381 caaaccatcc gcatggatat aggacgtgct aaaaaggata cttattttat caacatttca
    52441 gccgcaggaa gcctgacaga gctgacctat agtgtcccta gtcagctcaa aaccatgttt
    52501 ggctacctgg cttatctggc taagggagtg gagctcttgc ctcgagtgag taatgttccg
    52561 gtgaaaatca cgcatgatca tggcattttt gagggagagg tatcaatgat ttttgcagcc
    52621 atcactaatt ctgttggtgg ctttgaaaag attgccccag atgctaagct agatgatggc
    52681 atgtttaccc ttattttgat taaaacagcc aacctgtttg aaattgtgca cctgctgcgg
    52741 ttgatcattg acggtggtaa gcatgttacg gatcgccgcg tcgaatacat taaaaccagt
    52801 aaaatcacca ttgagcccca atcagataag cgcatgatga ttaatttaga tggtgaatat
    52861 ggtggtgatg cgccaattac cctagaaaac ttaaaaaatc acatcacctt ttttgcaaat
    52921 actgatttga tttcagatga tgcccttgtc ctagaccaag aggagctgga aatcgaagaa
    52981 atggtcaaga aatttgcgca tgaggtagag gatttagagc agggattgga ggaatagggc
    53041 tagttatgga taatgcagtt attgttcatt atcatagttg caagggacat tattttcaat
    53101 taagtctatg gcaatggcga gatggtaagc tgggcaagga cgcttatttt tcgaggtttg
    53161 acagctttgg agcagttgct tatctcactt atccagcacc ttattttttg agtcatgctt
    53221 atgtgattgt aaaggatcag ttttggcagc atcaaaccgt tgattttcgg attgagcgtg
    53281 attatggggt tccaaagact gaggtgtggc ttgttgatgg tgatcctacg gtttattatt
    53341 cgagacaggc tgctgtggct agtcgacatg atggtagatg tgatgtgcat gcctttgata
    53401 tggctgtcaa tagtcaggcc tttgacaagc gctggggctt tagtggctgg ctaggctttc
    53461 gctatcagcc tgaggagacg tcttttcgtt tgtgggctcc aacagcagaa aaggttgagc
    53521 tcattctcta tgcttcgact gatgagagag ctagtgttgc caaggttttg cccatgcagc
    53581 gtgggcagca gtactcgcca gatcatcatg cagaaaacac atgtggtgtg tgggacatca
    53641 gcctaagagg tgattataat taccatgctt attgctaccg ggtttattat cgcaggcgta
    53701 cctttagaga cactagggat ccttatgcga tcgcaacgac agcaaatggc aaaaggtcaa
    53761 ttgtcattgc accggagcat ttaagaccgc agggcttttc agtgaagcag ggtaaggagg
    53821 ctacctggcg cttagacaat cctaatcagg cggtgatcta tgaaatgcat gttcgcgact
    53881 tttcaaaatc agaaacctcg ggcgttagct tggctaatcg tggcaaattt aaggggctga
    53941 ttgagacagg cacgcgcaat gcttttggag attcaacctg ctttgattat gtcaagtccc
    54001 ttggcattac gcatattcag ctccagccgg tctttgacca tcatcaattc tttgatgaaa
    54061 atggagatta tgcctataat tggggctatg accctgaaaa ttacaatgtt ccagcagcca
    54121 gctttaccag taatccgcat gagccagcta cccgtatcct ggaattaaag gaggtcattc
    54181 aggcttatca tgatgcaggc atcaatgtga tcatggacgt ggtgtacaat catacctact
    54241 catcaagaga gtcagccttt cagctgacgg ttccggatta ttattaccgt atgaatccta
    54301 atggctcctt tcaaaatggc tctggctgtg gcaatgaaac ggctagtgaa aaggaaatgt
    54361 atcgcaaata catgcttgat tcgatcctat attggaccaa tgagtttaac attgatggct
    54421 tcaggtttga tctgatgggc ttacacgata ttgacaccat gaatcttatc cgacaagagc
    54481 tagataagat tgacccaagg atacttgttt ttggtgaggg ctgggatatg ggagttggtc
    54541 tggcagctga gcagaaggct aaaaaaggaa atgccagcca aatgcctgga atcggcttta
    54601 ttaatgatga tcagcgtaat gcagttaagg gggcagaggt ctatgggagc ttagagaagg
    54661 gctttgtatc aggtgcaccg acagaaggac ttgtagccaa gtctattttg ggcagtgatg
    54721 agctggtctc ttattgtacg cctagtcagg tgatcaatta tgttgaagct catgacaact
    54781 ataacctcaa tgatttgctg tgggttttga atccagagga cagcaagcag gatcatgtca
    54841 aacgggttca gctagcttca gctatgacga ttctcatgca agggatttac tttatgcagc
    54901 tgggtcagga atttttacga acaaagcttt acccaacagg tcaggataag gagctgacac
    54961 aggcagaccg agaaagggcg atgaattcct acaatgcacc tgacaatgtg aatcaggttg
    55021 actggagaca ggttagcttg gagcgcgaaa cggttgctat tatgaaaaaa ctaatctatc
    55081 tgaaaactaa aacagctttg ttttcatacc catcatttga gcaaatcaga cagcatgttt
    55141 acattgagca tgctggtgaa aatacgggct tcattagctt tacagtagaa gatgaaagaa
    55201 agtatcgatt gattttctct agttttagaa accgcttgca atcatctgct aatcatgtta
    55261 taattgaaac aaatgataag cgctttcaag atagtgagtc catgctagat gagctgacag
    55321 cgatgatcct tgacatcaca caatagcctg agtgttctca ggttattttt gtttgttgtc
    55381 aaggataaaa gggctgtagt tacagttagc agagacctat taggaccttg cttatcatat
    55441 cgcttagcgc cttgaaaaag ggtttaggag tagggaaaga agaggtgatg ggatggataa
    55501 tgacttagcg ctttatacct ttggcacagg tgagaatttt cacatacagg attatctagg
    55561 tgttcatcgg attaacaatg acacaggcac cagctatgtc tttagggtat gggcgcccaa
    55621 tgcagaggct gtcagcttga ttggagattt tactgattgg cagtccaatc cacttgagat
    55681 gagccgaaat gaggctggcg tgtgggaggt taccactagc ttgccgcagg aaggagatat
    55741 ttataagtat tgggttaggc gccaaggtgg tcagcttgtt gaaaaaattg atccagtggc
    55801 ctttctattt gaagctagac caggaacggg tgctattgtc aaaacccttc cagccaaaaa
    55861 atggcgtgat agcttatgga tgggacggcg aaagcgtttt ggctttaggc agcgtccggt
    55921 taatatctat gaggttcatg cccattcatg gaaaaaagac gaaaacgcaa ggccctatga
    55981 ctttagcaag ctaaaagaag agctcattcc ctatctcaag agcatgcact acactcatgt
    56041 tgagtttatg ccggtcatgg ctcacccctt agatatgagc tggggctatc agctgatggg
    56101 ctactttgcc tttgagtcaa cctttggaag cccagaagcc tttcaggatt ttgttgaggc
    56161 ctgtcatctt aataatattg gtgttttgat tgattgggtg ccgggacatt ttacacaaaa
    56221 tgatgacgcc ttagcttatt ttgacggtac agctacctat gaatatcagg atcaccatcg
    56281 tgctcataat tatggctggg ggccctaaat tttgatttgg gtaaaactca ggtacagtcc
    56341 tttttgattt caagtgccct tttttggctg gaggcttatc atgttgacgg cattcgagta
    56401 gatgctgtta gcaatatgct ttacttggat tatgatcaag gcccttggac tccgaatcaa
    56461 tacggtggca accaaaacct tgaggggata gcctttcttc aaaaattaac cacagttatc
    56521 aaggaaaaac accctgatgt gatgatgatt gcagaggagg cgacctcagc taccccaata
    56581 accagccctg ttgcagaagg gggactaggc tttgattata agtggaatat gggctggatg
    56641 aatgatattc ttaggtttta cgaagaggat ccttattacc gaaaatacga tttcaatctc
    56701 ttgaccttta gctttatgta ttgctttaag gagcattaca ttttaccctt ttctcacgat
    56761 gaggttgttc atggcaaaaa aagcctcatg cataaaatgt ggggggaccg ctacaatcaa
    56821 tttgcaggcc taagaaatct ttacacctat caaatctgcc acccaggcaa gaagctgctt
    56881 tttatgggat ctgagtttgg acagtttttg gaatggaaat acgatcatca attagagtgg
    56941 caaaatttag aggacgagct caatgccaaa atgcagcatt tcacagccag cctaaatcag
    57001 ctatataagg accatagcat gctgtggcaa aatgatgaaa cctatgacgg cattgatatt
    57061 attgatgcag acaataagga cgaatcagtc ttgtcgtttt gtcgtcaaaa caataaagga
    57121 gagctcctgc tttgtgtctt taacatgaca cctgttgaaa gaccaggctt taccataggt
    57181 gtgccgatag caggtcttta tcaagaaatt ttcaatacag agcttgaggc ctttggaggt
    57241 gtctggaagg agcacaatcc cttaaccaac acagtagcca agaaatggaa gacttatccg
    57301 cagaccttga gctttaccct gcctgcacta ggagcaagca tctggaaaat caagcgtcgt
    57361 cagaagcaat aagctattca ttgcttactt agctgtttca accaaaagaa gtcactacag
    57421 tcatgaaagg ataacgaaat gaagaatgga atgttagccc tcatattagc agggggacaa
    57481 ggaactcgct taggaaaatt gacacagagc attgcaaagc ctgctgtgca atttggaggt
    57541 cggtatcgta tcattgattt tgccctatcc aattgtgcta actcagggat tcataatgtg
    57601 ggggttatca cccagtacca gcctcttgcc ttaaataatc atattggcaa tggttcgtca
    57661 tggggcttag atggtattaa ttctggcgct acgattttac agccctactc tgcaacagag
    57721 ggaaatcgct ggtttcaagg aactagccat gctatctatc aaaatattga ttatattgat
    57781 agcattaacc ctgaatatgt gctgatcctg tctggtgatc atatttacaa aatggactat
    57841 gatgacatgc ttcagacgca taaggctaat atggctagct tgactgttgc tgtgattgat
    57901 gttcctctaa aggaagccag tcgatttggc attatgaaca cagataccaa tgaccgcatt
    57961 gtcgaatttg aagaaaagcc tgccaatcca aaatcaacca aggcttcaat gggtatttat
    58021 atctttaatt ggcagcgcct tcggaccatg ctggttgacg cagaaaaaaa caacattgat
    58081 atgtctgact ttggtcagca tgtgattccg tcttaccttg agtctggcga gcgtgtctac
    58141 acctataact ttaaaggcta ctggaaggac gtcggaacga ttgagtctct ctgggaagcc
    58201 aatatggaat acatcggtga ggaaaatgcc ctagacagtc gtgatcgttc ttggaagatt
    58261 tattctaaaa accatatcgc tccaccaaac tttatcacag aggacgccga ggtcaaggat
    58321 tctctggtag tagatggcag ctttatctct ggtaaggtca accattctat cttgtctacc
    58381 aatgtgcagg taagaaaggg agccgaggtt aaggattcct ttatcatgag cgatgttatc
    58441 attggtgagg gtgcaaggat tacacgagct attattggtg agggtgcagt cattggtgat
    58501 catgtgatca ttgatggcag caaggacgtt caagtcgtag gctataatga agtagtgggg
    58561 gtaccaaatg aagattgata aatattctgc cattctaggc agctcaattg gctttgctga
    58621 aatgaagggg ctaacagaca caagaccatt agccaaccta ccctttgatg ggaaataccg
    58681 gctcattgat tttcaattgt ccaaccttgc caatgcaggt gtccgtagca tctatggtat
    58741 ttttcgtggg caaaatatcc gctcagtgtt tgatcatatc aggtcaggtc gtgaatgggg
    58801 gcttaattcc ttactaagtc attatttcct tggcttttat aacaccaagg aggattctaa
    58861 agaggctgac aaggactatt atcagcagat tttgacctat ttaaagcgct cagggtcaga
    58921 tcagaccatt tacatgagct gtgatattct ctgcaatatt gagcttgggc aggttattca
    58981 tctgcacaat gccaaccatc gcaacattac ggttgtctac aagaaaatgc cgaccaaggc
    59041 catctctaag gctaacgata ttttagatat tgacgagaca gatactgttg ttgacaggcg
    59101 aagtctgtct gaggggcagg aggttgaaaa aatgtcagca ggcatttaca tcgtcaatac
    59161 cccatggtta attgaacaga tggaaaaaga agccgaaaaa gaaaaccctc aaaagctacg
    59221 cttcctctta cgtgatttga ttgtgtcaga gggcgctctt ggctttgaat atactggcta
    59281 tcttgccaat attcactctg ttaaatctta ttttgatgcc aatatggaca tgctggatcc
    59341 gcataagttt tattcactat tatatgctaa tcagaaggtc tacacgcgtg tcaaaaatga
    59401 agagtcaacc tattttgatg cggcttctga ggtgaacaat gcccaatttg cttcaggaag
    59461 cattgtcaag ggctatgtcg agcactcaat tgtctctcgc aattgtcgca ttacctcaca
    59521 ggcacgtgtt acaaatagta ttttattgcc aaaggcagtg attggtgagg gtgctgtcat
    59581 tgattatgct atcattgata aatccgtaag ggttgcacca ggtgttacta ttagaggaag
    59641 cgctgaggag ccaatagttg ttgccaaggg gactgaggtt gttgaggata tgataaaatg
    59701 aagataatgt ttgttgcagc agagggagct ccctttgcta agacaggtgg cctaggcgat
    59761 gtcattgggg cattgcctaa atcacttgtt aaaaatggtc atgaggtgtc tgtgatactg
    59821 ccttattatg acgtggttga tcaagccttt ggtcagcagg ttgaggacgt cttgtatttt
    59881 tatacgcagg ttggctggag acgccaatac gtgggcatta aaaagcttgt caaggataag
    59941 gtgacctttt actttattga caatcaaggt tatttcttta gaggcaggat ctatggtgat
    60001 tgggacgacg gtgagcgctt tgcctatttc cagctggctg ccatagaagc aatggagaaa
    60061 atcggggtta ttccagatat tttgcatgtg catgattacc ataccgctat gattcctttc
    60121 ctattgaaag aaaaatacca ttggattcag gcctatcaag cgattcggac agtttttacc
    60181 attcataata tcgcatttca agggcagttt gatcctggca tgctaggcga tttgtttgat
    60241 gttggtatag agcgctacga ggatggcacc ctgcgttggc atgattgctt gaattggatg
    60301 aaagcagcag tcctatatgc agatcgggta accactgtct caccctctta tgcgcatgaa
    60361 attcagacac cagcctttgg acaaggcttg gatcaagtca tgcgaatgga ggcaggcaag
    60421 ctatcaggca ttgtgaatgg tattgacact gacttattta acccagcaag ggatcctcat
    60481 ttgcctgctt cattttcagc agaagaccta tcaggcaagg cggctactaa acaggccttg
    60541 caggagcggt taggattacc agtcagggca gatgttccat tgattggtat ggtttcgcgc
    60601 ttgacggatc aaaagggctt tcagcttgtt cttgaggaat taccgcatat cttgcagcag
    60661 gacgttcagc ttgtcttgtt aggaacaggt gaccctgatt atgaggctgc cttttcatgg
    60721 tttgccaagg cctatccaga aaaactgtct gctaatatta cctttgatct gccattagct
    60781 cagcagattt atggggcctg tgatctcttt ttaatgccaa gtgcttttga gccctgcgga
    60841 ctttcgcaaa tgatggctat gagatatggc gcgataccga ttgtccatga gatcggcggc
    60901 ttgaaggata ctgttgcctc ctacaatgct tatgaaaaga ctggaactgg ttttggcttt
    60961 gatcagtttt caggattttg gttaacgcag acgctcttgt ttgcccttga tatttaccat
    61021 aaccacaagg aggattggca gactattcaa caacatgcca tgaccaagga tttttcatgg
    61081 gatacagcca gtctggccta ccttgattta tataaaagct tactataaca cagaaaagga
    61141 atgggaatgc acgtcacaaa agaacaattt attcgagatt ttaaagatac cttacatgag
    61201 gaacaattga tcaaggttcc tgccgcaaca gctgctgagc ttttcacctc attagcaaag
    61261 cttatccgta aatactatac agatacttgg attgaaagga atcgttcctt aaccgaacag
    61321 cagcaaaaaa ttgcctatta tttttcgatc gaatttttac caggaagaat gctagaaaca
    61381 aatcttctta atttaggcat tcttgataca gttaaagaag cctttgctga cttgggaatt
    61441 gattttcaag cagtgaagca tgcagagcac gacatggctc taggcaatgg aggtctagga
    61501 cgtttggcag ctgcctttat ggattcgcta gcgacaacag gctatccagg ctttggaaat
    61561 gggctgcgtt atcgttatgg gctgtttaag caacggattg tgaatggtta tcaggtagaa
    61621 ttaccagatt cttggtttgg ctctattggt aatgtctggg agatcagaaa ggatcatgac
    61681 attgtagacg tcaagctctt tgggaatgtt tacctaaaag ccaatcagga cggtaagcta
    61741 gcgccaatct atgagggagc tcaggttttg agagctgttc cctacgatgt tcctcagatt
    61801 ggctttgaaa atgatgtgat taacaatctt cgcctctggg acgtagaaat cccagaagaa
    61861 catgagcttg attacccaac catcgagtca agacgggcag tcaaggacat tactgccatt
    61921 ttgtacccag acgacagcag ctatgaaggc aaaaagctta gattgatcca agaatatttc
    61981 atgaccagcg caggcatcca aaccattatc aaatcctatt taaagcaggg cttgccactt
    62041 actgagcttc atcaaaaggt atctgttcat atcaatgata cccacccagc agtagctcca
    62101 gcagagctta tgcggctctt gattgacgac tatggcttag aatgggtaga cgcctgggcg
    62161 acaaccgtaa aaaccatgag ctataccaat catacgattt tgtcagaagc cttagaaaaa
    62221 tgggacgcag agctctttaa gactgtgctg ccccgcgttt atcaaatcat tttagagatt
    62281 gatcatcgct ttgttgctga aatggcgcaa aagggtattg atcctcagat cattgaaaac
    62341 actagaatcg ttaaggacaa ccagatttat atggctaatc ttgccattat tggtggctat
    62401 tcggtcaatg gcgttgccaa gctacataca gagttgttaa agacagatac ccttaaggac
    62461 ttttatgcct tgtatcctga aaaattcaac aacaaaacca atggtatcgt gcaaagacgt
    62521 tggacacaga ttgctgcgcc agagctatca gcagctattg accgcacgat tggcaaaggc
    62581 tggcgcaagg atattcacca gcttcgacaa ttgagtcaat ttacagaaga tccagctgtg
    62641 ctaaatgatt tttatcaggt aaaacaagca gctaagcagc gcctagccag gtatatcctg
    62701 gaaaaaacag gtcttgaggt ttcaacagag gctatttttg atgtgcaggt caaacgccta
    62761 catgcctaca agcggcagct cctgaacgtc ctgcatatta tgaagcttta ccttgatttg
    62821 aaggctaatc cagatttaga tatggtgcct agagtcttta ttttcggcgc aaaggctgca
    62881 ccaggctatc attttgccaa gtcggtgatc aaaatcatca atgagctggc taatctcatt
    62941 aaccatgata ccagtctcaa aggaaagcta aaggttgttt ttcttgaaaa ttataacgtg
    63001 agtctagcag agctcattat ccctgcggca gatatttcag agcagatttc actggcctcc
    63061 aaggaagcct caggaacatc aaacatgaaa tttatgatga ctggtgctat caccctagcg
    63121 acccttgatg gggcaaacat tgaaatcaaa gacgaggtcg gagaggaaaa cattgtgatc
    63181 tttggtatgg ataaggatca ggtctatgac cactatgcca agcatgatta ttattcaaga
    63241 ggcctatatg agagcgaccc tcagattaaa gcagtagtcg acgcttttgt caatggcacc
    63301 attccaaata gtcaacacga aggtatggaa atctatgatg ccctaatcac gcataatgat
    63361 gaatacttct tgctagaaga cttttcttcc tatgtaaaag cacaggctaa gattgatcgg
    63421 ctctaccgcc aaaaggatag atggtcaaaa atgtcgctca tcaacattgc ccattctgac
    63481 aagtttacat cagatgatac catcacccag tatgccaagg acatttggca gctaaaacgc
    63541 taatccatca aggaagaaaa agcattagtt accttagatt gaagagagtg tcttttgaga
    63601 ccattttctt caatcttttt tgattgcaaa agaccttggg aatcagatca gctgcctgcc
    63661 taatactttg gcctatcaag gtattttgga atttgttaat ctttttgtta taatagtggt
    63721 gtgaagctat tttttaaatg aaaaagccaa cacttcaaga tggtgttaaa gtaaggttag
    63781 tattagtcta agaaagcgta accacattaa agaaagctgt tgacattctc aattttaagg
    63841 aatagaataa caaagtaaaa aatttttaaa aggagtattc tattatgaat cctattttcg
    63901 cattggctct tgcctgcttt ggtgtatcac ttgccgaagg ctttttgatg gctaatctct
    63961 ttaaatcagc gtcacgccaa ccagaaatta tcggtcaatt acgttccttg atgatcctag
    64021 gtgttgcctt tattgaaggt accttcttcg ttacccttgt tatggccttc attctaaaat
    64081 aacagcctat ttgatataga aaaggagggt attaaatgga agaagctaaa gtaccgatgg
    64141 tagagcttgg tccaataacc tttaatttga ccctacttgc tgtttgtatt gttactatcc
    64201 tactgatatt tggctttgtt ttttgggcaa gtcgtcagat gacattaaaa ccaaaaggca
    64261 agcaaactgc gttagaatat ttaatcagct ttgttaatgg tattggggaa gagcatttgg
    64321 atagtcatct tcagaagtct tattcgcttt tactttttac catttttctt tttgtggcag
    64381 ttgccaacaa cttgggctta tttacaaagc tagaaacaac cagtggctac aacctatgga
    64441 catcgccaac agctaatttg gcctttgacc tagccctatc tctgtttgtg acgcttcttg
    64501 ttcatatcga aggcattaga cgtcgtggtt ttggcgctta tttaaaacgc tttgcgacac
    64561 cttggccaat gactccgatg aacctattag aagaatttac caacttccta tcacttgcta
    64621 tcaggctgtt tggtaatatc tttgcaggag aggttgtgac aggcttgatt gttcagctgg
    64681 ccaattatcg cctgtattgg tggccaattg ctttccttgt taatatagca tggacagcct
    64741 tttccatatt tatttcctgc atacaagcct ttgtatttac aaaattaaca gcaacgtatt
    64801 taggaaaaaa agttaatgaa tcagaagaat aagaagggag gacaaacgaa tgtcagttac
    64861 aattggtgag ctcattggga attttattct ggtaacaggc tctgtcatcg tcttgttgct
    64921 cttgattaaa gcctttgctt ggggtgctat cgaagctgtt ttacaggcac gctcacagca
    64981 aatttcacag gatattgacc aagcagagca ggcgcgtctc aacgcccagc agcttgaaaa
    65041 ggaaggtcaa gccaatctag aagccagcag atcagaggct agtcagattg ttgaggcagc
    65101 caaagaaact ggtaaagcac aggagacacg cattgtagca gaggctacag aagaggcaga
    65161 tcgcctaaaa gcagcagcgt tgacagatat cgaacacagc aagtcagagg ctatttcagc
    65221 cgttaagaca gaaatgtcag atttgacagt tttactagca gaaaaaatta tgggagccaa
    65281 tcttgataag gcggctcaaa gccagcttat tgatcgctat cttgatgatt taggagaggc
    65341 ttaatgacca aaaaagaaca agctcttatc gagcaatatg caaaaagtct tgtgcaggtc
    65401 tgtcaggagc gagacactct tgaagcactg caggctgatg tgcttgccat tttagaggtt
    65461 tttaaagcta ctaatcttgc taagacattg tcaagcttag cggttccacg tgctaaaagg
    65521 cttgagctag taaggcagct tcaaggagat aatatcgttt atctgaataa cttgctagaa
    65581 gttatgctgc aaaatgagcg tgaagcttat ttatatcaag tgcttctaag ggttttatcc
    65641 gagctggcta gtgtctcaaa tcaatatgac gtgacagtta catcagcagt tcctttaagt
    65701 gaggagcaaa agcagcgtgt gcgtacagtg gtttcaaaga gacttgcagt aaagacaggt
    65761 cgcttaatcg aaaaggtaga tccttcttta attggaggat ttatgattag cgtcaataat
    65821 aaggtaattg atacaagcat tcgtcgtcaa ttacaagcat ttaaaatgaa tttaaaatag
    65881 aaagtggtgt gacttttggc aattaatgca caagaaatta gcgctttaat taaaaagcaa
    65941 attgagaact tccagccaaa tttcgatgtc acagaaactg gagttgttac ctatattggt
    66001 gatgggattg cacgtgctcg tggcttagac aatgcgatga gtggcgagct tcttgaattt
    66061 tcaaatggta ccttcggtat ggctcaaaac ctagagtcaa acgatgttgg tatcattatt
    66121 cttggtgatt tttcaacgat tcgtgagggt gatgaagtca aacgtaccgg taaaattatg
    66181 gaagtgccag tcggtgaagc tctcattgga cgtgtggtca atccacttgg tcagcctgtt
    66241 gatggcttag gtgacattga gacaactggc tttaggcctg ttgaaactcc agctcctggt
    66301 gttatgcagc gtaagtctgt ttttgagtcc ttacaaaccg gtctaaaggc tattgatgct
    66361 ttggttccga tcggtcgtgg ccagcgcgag ctgattatcg gtgaccgtca gacaggtaag
    66421 acgtctgtag ccattgatgc catcttgaat caaaaggggc aggacatgat ttgtatctat
    66481 gtcgctattg gtcaaaagga atcaacagtt cggacacagg ttgaaaccct acgtcgttat
    66541 ggtgctttgg attataccat tgttgtaacg gcttctgctt cacagccatc acccttgctg
    66601 tttattgcac cttatgctgg tgttgcgatg gcagaagagt ttatgtacaa tggcaagcac
    66661 gttttgattg tttatgatga cctgtctaag caggcggtag cttatcgtga attgtcgctc
    66721 ttgcttcgtc gcccaccagg tcgtgaggcc tatccaggag atgttttcta cctgcatagc
    66781 cgcttgcttg agcgctcagc taaggtgtct gatgacttag gtggtggctc aattacagcc
    66841 ttaccattta ttgagacgca ggctggggat atctctgcct acattgcgac aaacgtgatt
    66901 tcgattacag atggtcagat tttcttgcaa gaggatctct ttaactcagg aatccgccca
    66961 gctattgatg ctggctcgtc agtatctcgt gtcggtggct ctgcacagat caaggctatg
    67021 aaaagggttg cagggacttt gcgtcttgac ctagcctctt atcgtgagtt agaagccttt
    67081 acacaatttg gctcagatct agatgcagca acgcaagcaa aattaaatcg tggtcgtcgt
    67141 actgttgaaa tcctaaagca gccactgcac aagcccttgc ctgttgaaaa gcaggtggtc
    67201 attttgtacg ctttgacgca tggattttta gatgatgttc ctgtagatga tattttagcc
    67261 tttgaagaag cactttatga ctactttgat gcgcattatg atcacttatt tgaaacaatc
    67321 cgtacaacca aagaccttcc gcaggaggct gagctggacg ttgctattca ggccttcaaa
    67381 gcacagtcaa actttaaata aaagaggggg gtactagtat ggcaggctct ctaagtgaaa
    67441 ttaaggctaa aatcatttca accgaaaaaa caagcaaaat cactagcgcc atgcgtatgg
    67501 tttcttctgc aaagcttgtt aaatctgagc aagcagctcg tgattttcaa atctatgctt
    67561 caaagattcg tcagattaca acagacttac tgaaatcaga cctgacaaca ggctcagata
    67621 atcccatgct ggtgtctcgt cctgtgaaaa agacaggcta tattgttatt acctctgata
    67681 aaggactggt cggtggttac aattcaaaaa tcttaaagtc cattatggac atgattcagg
    67741 aataccatgc cgctggcgat tatgagatta tctcaattgg cagcatcggc tcagattttt
    67801 ttaaggccag aggtatgaat gttgcctttg agctgcgcgg cctagcagat cagccaagct
    67861 ttgatcaggt cggaaggatt atctctcagt ctgtaggtat gtttgtcaat gagatttttg
    67921 atgagctgta cgtctgctac aatcaccatg tcaatagctt gacgagccag gttcgggttc
    67981 agcgcatgct gccgatttct gatttggttg ccgaggaggc cgcagaagaa ggtgtcactg
    68041 gatttgaatt agagccaaac cgtcatgtga ttttggagca gctgctgccg caatttactg
    68101 aaagcttaat ttatggtgcg attattgatg caaaaacagc agagcatgct gctggcatga
    68161 ctgcaatgca gactgccact gacaatgcca agcatgtgat caatgatttg accatccagt
    68221 acaatcgtgc gcgtcaggcg gccattacac aagaaattac agaaattgta gctggtgcta
    68281 atgcacttga ataagcttat tgtatgctga tagcgctcta gcagagacct attagcactt
    68341 aatgtcatct tcaaagctag atgacatttg ggattaatga gctaggggcc ttttaccctt
    68401 agctactcga atttagaaaa attcagctta atcccctact atcgaatata aggagaaaaa
    68461 catgagctca ggcaaaattg ctcaggttgt tggtccagtt gtagacgttg tgtttgcgag
    68521 tggggacaaa ctaccagaga ttaataatgc gttgatagtt tataaagatg gcgataaaaa
    68581 gcaaaaaatc gttctcgagg ttgccctaga gcttggagac ggtatggtac gtacaattgc
    68641 tatggaatca accgatgggc ttacacgtgg attagaggtt cttgatactg gtcgtgccat
    68701 tagtgtacca gttggtaaag agactctagg tcgtgttttc aacgttcttg gtgaaaccat
    68761 cgacctagaa gcaccatttg cagatgatgt taatcgtgaa ccgatccata aaaaagcacc
    68821 agcctttgat gaattgtcaa catcatcaga aattcttgaa acaggtatca aggttattga
    68881 cctgcttgcc ccttacttaa agggtggtaa ggtcggtctt ttcggtggtg ccggagttgg
    68941 taaaaccgtt cttatccaag aattaatcca caatatcgct caagagcatg gtgggatctc
    69001 ggtatttacc ggtgttggtg agcgtacgcg tgaaggaaat gacctttact gggaaatgaa
    69061 ggaatcaggc gttattgaaa aaacagccat ggtttttggt cagatgaatg aaccaccagg
    69121 agcccgtatg cgtgttgcct tgaccggctt gacaattgct gaatatttcc gcgatgttga
    69181 aggccaagac gtcctgctct tcattgacaa tattttccgc tttactcaag caggctcaga
    69241 ggtatcagcc cttctaggtc gtatgccttc agccgttggt taccagccaa cacttgccac
    69301 tgaaatggga caattgcaag agcgtatcac ctcaacgaaa aaaggctctg ttacctctat
    69361 ccaagccatc tacgtgccag ctgatgacta cactgatccg gcgccggcaa cagcatttgc
    69421 tcacttggat tctacaacta accttgagcg taagctgacg cagatgggga tttacccagc
    69481 ggttgatcca ctggcttcaa gttcacgcgc gctgtcacca gaaattgttg gtgaggagca
    69541 ctatgcagta gccacagagg ttcagcgtgt cttgcagcgc tatcgtgaat tgcaggatat
    69601 cattgctatc ttaggtatgg acgagctgtc agaagaggaa aagacattgg taggacgtgc
    69661 gcgtcggatt cagttcttct tatcgcaaaa ctttaacgtc gcagaacagt ttacaggcct
    69721 tcctggctct tatgttccag ttgccgaaac cgttcgtggc ttcaaggaaa tcctagaagg
    69781 aaagcatgac caccttccag aagacgcctt tcgtgctgtt ggaccaattg aggacgtgat
    69841 cgaaaaagct aagaaaatgg gcttttagtg aggtgatgcc atgacacaaa tgactgttca
    69901 ggtggttacg ccagatggga tcaaatatga tcatcatgct aagttcatct cagtaacgac
    69961 accagatggt gagatgggga tcttacctaa ccacatcaat gtgattgctc ctttacaggt
    70021 gcatgaaatg aagattcgtc gtgtcagtga agacgatcgc gttgattggg ttgctatcaa
    70081 tggtgggatc attgagatca aagacaacgt ggttaccatt gttgcagatt cagccgaacg
    70141 tgatcgtgat attgatgtta gccgagcaga gcgggcaaaa ttgcgagcag agcgtgacat
    70201 tgcagaggct gaaaccactc atgatattga tgaggtgcgg cgtgctaagg ttgctttgcg
    70261 acgtgccttg aaccgcatca atgttagtaa aaaatagtaa aatgagtcta acctaccaat
    70321 ttaaccaaga cagagcgagt agcgctgctt aggaaagggt gtagatagac tcttttatct
    70381 ttttatagaa aaaataccct cttt
//
LOCUS       DARYYD010000002        59754 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.002, whole genome shotgun sequence.
ACCESSION   DARYYD010000002 DARYYD010000000
VERSION     DARYYD010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59754
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.002"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            74..1273
                     /locus_tag="TV188_000065"
                     /pseudo
     CDS             74..1273
                     /locus_tag="TV188_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842898.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
     gene            1367..1522
                     /locus_tag="TV188_000066"
     CDS             1367..1522
                     /locus_tag="TV188_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1533468.1"
                     /translation="MEKQNSLTQFQELNSSELNQITGGDWWSEILNFNRSQKYKHTSV
                     GSNNIIV"
     gene            complement(1704..2169)
                     /gene="tnpA"
                     /locus_tag="TV188_000067"
                     /pseudo
     CDS             complement(1704..2169)
                     /gene="tnpA"
                     /locus_tag="TV188_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775157.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(2456..2929)
                     /gene="tnpA"
                     /locus_tag="TV188_000068"
     CDS             complement(2456..2929)
                     /gene="tnpA"
                     /locus_tag="TV188_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018373723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HEL1533469.1"
                     /translation="MAKTSYSLSHTKWMCKYHIVFTPKYRRKSIYYKIRQDLIDIFRH
                     LCQYKGVEIIEGHMMPDHVHMLVLLPPKLSISDFMGYLKSKSALMIFDKHANLKYKYG
                     NRKFWARGYYVSTVGLNKRTVAKYIREQEKNDIALDKLSVKEYEDPFSDGSFKTR"
     gene            complement(3211..3576)
                     /gene="rplL"
                     /locus_tag="TV188_000069"
     CDS             complement(3211..3576)
                     /gene="rplL"
                     /locus_tag="TV188_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEL1533470.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     GGAEEATKDSFDVELTSAGDKKVGVIKAVREITGLGLKEAKGLVDGAPANIKEGVAAA
                     EAEEIKAKLEEAGATITLK"
     gene            complement(3641..4141)
                     /locus_tag="TV188_000070"
     CDS             complement(3641..4141)
                     /locus_tag="TV188_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEL1533471.1"
                     /translation="MSEAIIAKKAEQVELIAEKMKAAVSIVVVDSRGLTVDQDTVLRR
                     SLRESGVEFKVIKNSILTRAAEKAGLDELKDIFVGPSAVAFSNEDVIAPAKVINDFAK
                     TAEALEIKGGAIEGVVSSKEEIQALAALPNREGMLSMLLSVLQAPVRNVAYAVKAVAE
                     SKEGAA"
     misc_feature    complement(4170..4305)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(4437..5078)
                     /locus_tag="TV188_000071"
     CDS             complement(4437..5078)
                     /locus_tag="TV188_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEL1533472.1"
                     /translation="MIEKGKFIASWLWLLALAVLITIYLSWLLYPIEVDYLQLEQAVL
                     MCKKSILHNYNILLTYLTNPFVRELKLASFSASRAGLKHFTDVKMLFHITQLIFSLLM
                     LPTIIYFYQSIKKGRVMLLRRGLIAAALLPIVIACFALMIGFDQFFTLFHQILFVGDS
                     SWLFDPLTDPVIWILPEAFFGHCFALFFFIYEMILWSLIGLSYSNQSSQVAYH"
     gene            complement(5075..5842)
                     /locus_tag="TV188_000072"
     CDS             complement(5075..5842)
                     /locus_tag="TV188_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEL1533473.1"
                     /translation="MPYKAYLIDLDGTIYQGKNRIPAGERFIKRLQEKGIPYLLVTNN
                     TTRTPEMVQEMLANQFNVHTGLETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIA
                     EAGYTEDTENPAYVVVGLDTEVTYEMLSIATLAIQKGALFIGTNPDLNIPTERGLMPG
                     AGALNALLEAATRVKPVFIGKPNAIIMNKALEILKVPRSEVAMVGDNYLTDIMAGIQN
                     DMATILVTTGFTKAKEVPSLPIKPDHVLASLDEWELL"
     gene            complement(5842..6594)
                     /locus_tag="TV188_000073"
     CDS             complement(5842..6594)
                     /locus_tag="TV188_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEL1533474.1"
                     /translation="MGLRYSESLKLSFDFCDVKADVKLPLLLAHCLMVSARQSAEIGR
                     GNEVLLQQYGLIWVVTDYDVTIDRMPRFGETVTIETQAISYNKLFCYRQFHIYDQAGH
                     AIMTILSHFALLNPQTRKAAAIPDDLVVPYQADFVKKIKRPIKIDELQDPMVQAYQVR
                     YFDIDMNGHANNSKYLDWMYDVLGYEFLLHHRPCHLTLTYIKEVRPSTQITSGYHLEH
                     LTSYHEIRSSGQLNAQAIIKWQPITTKESETN"
     gene            complement(6605..7735)
                     /locus_tag="TV188_000074"
     CDS             complement(6605..7735)
                     /locus_tag="TV188_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEL1533475.1"
                     /translation="MSKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDAYLEALIKE
                     FESYQISSLKTLYIGGGTPTAITANQLDYLLSHLQQHLQLDQLEEFTIEANPGDLTED
                     KIAVLRQSAVNRISLGVQTFNDKQLKQIGRSHTEAQIYTTIASLKEAGFQNMSIDLIY
                     ALPGQTMQQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLHLPTEDLEAEM
                     FEYIISEMEASGFEHYEISNFTKPGFESRHNLMYWNNDEYFGCGAGASGYLDGIRYRN
                     RVPIQHYLKAVADGNARLSEEVLTKEEMMEEELFLGLRKKSGVSVSRFQEKFGLSFES
                     RYGPVVRELQNQGLLVEDKDFIRMTKKGLFLGDSVAEKFILD"
     gene            complement(7802..8488)
                     /locus_tag="TV188_000075"
     CDS             complement(7802..8488)
                     /locus_tag="TV188_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1533476.1"
                     /translation="MLSSSIRIGGNMIKHRVDRIASQLDELTQKLYLTMIPEYQEGYA
                     NYIYQTDQPDVQRRRIKHINKTFHRLLSESSFYLMPMTQHSAEIIAHDWIYSPAYECY
                     SMTADPEDYQSILSPKARGEHYFQVLRNGVLFGFASFFEQESELEIGLGMAPDTTGQE
                     DGVSFLGSIEAFASTTYPQETYVLNVASFNKGAQSLYQKMGYQPTSSFEQYANGSSHS
                     FVRMEKKKQP"
     gene            complement(8522..9874)
                     /locus_tag="TV188_000076"
     CDS             complement(8522..9874)
                     /locus_tag="TV188_000076"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEL1533477.1"
                     /translation="MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPRV
                     FVARDTRISGEMLEAALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASH
                     NPALDNGIKFFGSDGFKLADEQELEIEALLDAKEDLLPRPSAEGLGALVDYPEGLRKY
                     ERFLVTTGADLDGLKIALDTANGAASVSARNVFLDLNADITVIGENPNGLNINDGIGS
                     THPEKLQDLVTETASDIGLAFDGDSDRLIAVDENGAIVDGDKIMFIIGKYLSEKGLLA
                     KNTIVTTVMSNLGFHKALDSCGIHKKVTAVGDRYVVEEMRQFGYNLGGEQSGHVIIMD
                     YNTTGDGQLTAVQLTKIMKETGKTLSELASEVTIYPQKLVNIRVDNSMKERAMEVPAI
                     AEVIAQMEGEMAGNGRILVRPSGTEPLLRVMAEAPSNEEVDYYVDTIAAVVRAEIGLD
                     "
     gene            complement(9927..10883)
                     /locus_tag="TV188_000077"
     CDS             complement(9927..10883)
                     /locus_tag="TV188_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEL1533478.1"
                     /translation="MKRFLNSRLGLGLVSIFFAIILFLTAASSSHNHSNSQIYSPIET
                     YTHSLKDVPIDIKYDSDQYFISGYSYGAEVYLTSTNRIKLDSEVNSDTRSFKIVADLT
                     KSKPGTATVTLKVINLPTGVTATVSPDKISVTIGNKKTKTFPVRGSVDSKQLAKGYEI
                     SKIETGIDKVEVTSDESTIALIDHVVAKLPDDQVLDANYSSRVTLQAVAADGTILASA
                     IDPAKANLSVSVKKITKSVPIRVEAVGLMDDSLSDIQYKLSKQTAVISGSREVLETID
                     EVVAEVNISDVTKNTSKTVSLVSNQVSIEPSVVTVQLTTIKK"
     gene            complement(10880..11731)
                     /locus_tag="TV188_000078"
     CDS             complement(10880..11731)
                     /locus_tag="TV188_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEL1533479.1"
                     /translation="MSNLSSIDTKFLLSLIDDPLMLVVHLLDILIVAYLIYRFIKSLA
                     GTKIMSLVQGVIFFIIIRVIAEWIGFTTITYLMNQVITYGVIAGVVIFAPEIRAGLEK
                     FGRSTQVFLQKQSLSDEEMLVDALLKSVAYMGPRKIGALIAIEQTQTLQEYIATGIPL
                     NADISSQLLINIFIPNTPLHDGAVIVANNKIAAACAYLPLSESMSISKEFGTRHRAAI
                     GLSENSDAVTIIVSEETGAVSIARKGQFLHDLSTEELEAVLKTHLMNEPGATLPWYKK
                     ILGGKAK"
     gene            11833..13176
                     /locus_tag="TV188_000079"
     CDS             11833..13176
                     /locus_tag="TV188_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEL1533480.1"
                     /translation="MKLKTLLAIAAGRTAQLILNKIGRGSTYPGRLALMWDKDILDTL
                     AKDYEIVVVTGTNGKTLTTALTVGILKEAFGEVLTNPSGANMMTGITSAFLSAKRKKT
                     GKPIAVLEIDEASLARVTTYIKPSLFVYTNIFRDQMDRYGEIYTTYQMIVDGASQAPK
                     ATILANGDSPIFASKDLVNPVKYYGFDTPKHEPRLAHYNTEGILCPKCEQILRYRLNT
                     YANLGDYTCLNCDFQRPKLDYKLTQLTSITHHSSAFVIDDQTYRINVGGLYNIYNALA
                     AVAVAEFFGISADQIKAGFNKSKAVFGRQETFSINGKACTLVLIKNPVGASQALEMLR
                     LADYPFSLSVLLNADYADGIDTSWIWDADFELINQMDITEINAGGVRHSEIARRLRVT
                     GFDEAKITSFDKLEGIMQAIENQEAEHAYILATYTAMLAFRELLASRHIVEKEMI"
     gene            13176..13964
                     /locus_tag="TV188_000080"
     CDS             13176..13964
                     /locus_tag="TV188_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEL1533481.1"
                     /translation="MTYTSLQSPENRDYQYDLHIAHLYGNLMNTYGDNGNVLMLKYVA
                     EKLGAKVRVDIVSIGDTFDQDDYDIVFFGGGQDYEQAIVARDLPSKKEALAAYIHQNK
                     VLLAICGGFQLLGQYYIQANGLKINGIGVMGHYTLNQDNNRFIGGIKIHNDDFDETYY
                     GFENHQGRTFLSDDEKPLGRVIYGNGNNKEDQTEGVHYKNVYGSYFHGPILSRNVSLA
                     YRLVTTALKEKYGSTVSLAAYDKILQHETSEEYADVKSKASFDS"
     gene            complement(14588..15577)
                     /locus_tag="TV188_000081"
     CDS             complement(14588..15577)
                     /locus_tag="TV188_000081"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEL1533482.1"
                     /translation="MKYIVNKSHNPAFNIALEAYAFRELVDEDELFILWINEPAIIIG
                     KHQNTIQEINKEYIEQHGIHVVRRLSGGGAVYHDLNNLNYTIISNKTTEGAFDFKTFS
                     QPVIETLADLGVKANFTGRNDIEIDGKKICGNAQAYYKGRMMHHGCLLFDVDMTVLGD
                     ALKVSKDKIESKGVKSVRARVTNILNELPEKISVEAFSDKILVKMKETYPDMTEYVLS
                     EDELAKIQQSAEEQFGSWDWTYGKAPEYTIERNVRYPAGKISTFANVENSVIKNLKIY
                     GDFFGIKDVQDIESLLIGCKYEYADVLERLQTIDTTQYFSRMTVEEVAKAIVA"
     gene            complement(15819..17588)
                     /gene="lpdA"
                     /locus_tag="TV188_000082"
     CDS             complement(15819..17588)
                     /gene="lpdA"
                     /locus_tag="TV188_000082"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEL1533483.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKIIRQAGETVPVTEVIGYIGAAGEAIDVSSPAAADVNVARTTEDL
                     QAAGLEVPKAPDQGSAPSAPKAELAADEYDIIVVGGGPAGYYAAIRGAQLGGKIAIVE
                     KSEFGGTCLNVGCIPTKTYLKNAEILDGIKIAAGRGINLASTNYTIDMDKTVDFKNTV
                     VKTLTGGVQGLLKANKVTIFNGLGQVNPDKTVTIGVQTIKGRNIILATGSKVSRINIP
                     GIDSKLVLTSDDILDLREMPKSLAVMGGGVVGIELGLVWASYGVEVTVIEMADRIIPA
                     MDKEVSLELQKILSKKGMTIKTSVGVSEIVEANNQLTLKLNNGEEVVAEKALLSIGRV
                     PQMNGLENLNLEMDRNRIKVNDYQETSIPGIYAPGDVNGTKMLAHAAYRMGEVAAENA
                     MHGSTTRKANLKYTPAAVYTHPEVAMVGLTEEQAREQYGDVLIGKNSFTGNGRAIASN
                     EAHGFVKVIADAKYHEILGVHIIGPAAAEMINEAATIMEAELTVDELLLSIHGHPTFS
                     EVMYEAFADVLGEAIHNPPKRKK"
     gene            complement(17797..19206)
                     /locus_tag="TV188_000083"
     CDS             complement(17797..19206)
                     /locus_tag="TV188_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEL1533484.1"
                     /translation="MAVEIIMPKLGVDMQEGEIIEWKKQEGDTVSEGDILLEIMSDKT
                     NMELEAEDSGVLLKITRQAGETVPVTEVIGYIGAAGESVDNSTASSEKTTEIPVPTSA
                     EANTTTVPKEAASTAPQVASVANAPAFGEKVRATPAARKAASEMGIELNQVPGTGPKG
                     RIHKEDVEGFKGAQPKATPLARKIAADKGVDLAAVVGTGIGGKITKEDILAVLGAAAP
                     AVEKASIAEEKPAKELPEGVEIKKMSAMRKAISKGMTHSYLTAPTFTLNYDIDMTEMI
                     ALRKKLIDPIMAKTGLKVSFTDLIGLAVVKTLMKPEHEYMNASLINDANDIELHRFVN
                     LGIAVGLDDGLVVPVVHGADKMSLSEFVLASKDVIKKAQGGKLKATEMSGSTFSITNL
                     GMFGTKTFNPIINQPNSAILGIGATIPTPTVVDGEIVARPIMAMCLTIDHRLVDGMNG
                     AKFMVDLKKLMENPFELLI"
     gene            complement(19330..20328)
                     /locus_tag="TV188_000084"
     CDS             complement(19330..20328)
                     /locus_tag="TV188_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEL1533485.1"
                     /translation="MTETKLMALREAINLAMTEEMRKDDTIYLMGEDVGVYGGDFGTS
                     VGMIEEFGAKRVKDTPISEAAIAGAAIGSAITGLRPIVDLTFMDFITIALDAIVNNGA
                     KNNYMFGGGLITPATFRVASGSGIGSAAQHSQSLEAWLTHIPGIKVVAPGTANEAKGL
                     LKSAIRDNNIVIFMEPKALYGKKEEVNQDPDFYIPLGKGDIKREGTDVTIVSYGRMLE
                     RVLQAAEELAADGINVEVVDPRTLIPLDKELIINSVKKTGKLMLVNDAYKTGGFIGEI
                     AAMVTESEAFDYLDHPIVRLASEDVPVPYARVLEQAILPDVAKIKAAIVKMVNKGN"
     gene            complement(20408..21376)
                     /locus_tag="TV188_000085"
     CDS             complement(20408..21376)
                     /locus_tag="TV188_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEL1533486.1"
                     /translation="MVTVSKEQHLDMFLKMERIREFDSRINKLVRRGFVQGMTHFSVG
                     EEAANVGAVAHLTYDDIIFSNHRGHGQSIAKDMDLNKMMAELAGKVTGVSKGRGGSMH
                     LADFEKGNYGTNGIVGGGYALAVGAALTQQYKGTNNIVVAFSGDGATNEGSFHESVNM
                     AATWKLPVIFFIINNRYGISMSINNATNTPHLYTRAEAYGIPGFYCEDGNDVMAVYET
                     MSKAVEHVRGGNGPAVVEVESYRWFGHSTADAGKYRTKEEVDEWKEKDPMLKYRAYLT
                     GEGIATDEELDALQAQVKQEIDDAYEFAQNSPDPDISVAFEDVWVD"
     gene            complement(21882..23792)
                     /locus_tag="TV188_000086"
     CDS             complement(21882..23792)
                     /locus_tag="TV188_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1533487.1"
                     /translation="MIILQGNNIERSFSGEVLFQNLSLQVGERDRIALVGPNGAGKST
                     LLKILVGEEEPTSGEVSRKRDLTLSYLAQNSRFESDKTIYQEMLKVFAELRVDEQRLR
                     QMEADMASRSGQALDQLMSDYDRLSESFRLRNGFTYESDIRAILNGFKFDESMWEMKI
                     SELSGGQNTRLALAKMLLEKPELLVLDEPTNHLDIETIAWLEHYLVNYQGALIIVSHD
                     RYFLDKVATITLDLTKNSLDRYVGNYSRFIDLKAEKLAAEEKHYDKQQKEIAKLEDFV
                     QKNIVRASTTKRAQARRKQLEKLERLDKPSSSRKSASMTFQIDKPSGNVVLQVTDAAI
                     GYNDHILAEPIHLDVRRLDAIAIVGPNGIGKSTLLKSIIGEIPLIKGTCHYGTNVETG
                     YYDQTQSHLTGSNSVLEELWRDFPTTAELEIRSRLGAFLFSGEDVKKSVAMLSGGEKA
                     RLLLTKLSMKKDNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     KVLEITEAGSTLYLGDYDYYVEKKAEREELARLAAADHVVETDVAEAAVTDYQLQKAS
                     QKEYRRLTRRFEEIEQTLEGLEAQAKAIEAQMLVSNDTTQLIDWQKELDQLNQKQETL
                     LLEWEDIAGQLE"
     gene            complement(24202..24987)
                     /locus_tag="TV188_000087"
     CDS             complement(24202..24987)
                     /locus_tag="TV188_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEL1533488.1"
                     /translation="MASISIEYHSEILAMERHVKVIYPDQSELSPEEQGYQDIPVLYL
                     LHGMGGNENSWQKRTNIERLLRHTNLIVVMPSTDLGWYTDTTYGMNYYQAIAEELPRL
                     LASFFPNMTTKREKTFVAGLSMGGYGAFKWALKSNRFSYAASFSGALHFSPEMLLQQG
                     IGELPYWQGVFGDLNAPDIKKHYLTSIAAESDGQTQLYAWCGYEDFLFEANEKAVAEL
                     RRLGLTIDYRKDHGRHEWYYWNQQLEALLDWLPIAYHKEERLS"
     gene            complement(25093..26754)
                     /locus_tag="TV188_000088"
     CDS             complement(25093..26754)
                     /locus_tag="TV188_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1533489.1"
                     /translation="MTDINIIALGGVREYGKNFYLVEINDSMFILDAGLKYPETEQLG
                     VDLVIPSLDYVIENKDKVQGVFLSHGHADAIGALPYLLAEVPVPVFGSELTIELAKLF
                     VKANNSTKRFKNFHVVDSDTEIEFKDGLVSFFKTTHSIPESLGVVIGTDKGNIVYTGD
                     FKFDQASREGYQTDLARLADIGKEGVLALLADSANATSNEQTASEAEVGEEMDKVIAH
                     ADGRIIIAAVASNLVRIQQVFDSAAAYSRRVVLTGTDAENIVRTALRLKKLVIADEKL
                     LIKPKDMSKFEDHELIVLEAGRMGEPINSLQKMAIGRHRHVQIKDGDLVYIVTTPSAA
                     KEAMVARVENLIYKAGGSVKLITQHLRVSGHANARDLQLMINLVKPKYLFPIQGEYRD
                     LAAHAHLAEEAGILPENIHIMKRGDIMVLDEDGFLHEGAVPASDVMIDGNAIGDVGNI
                     VLRDRKVLSEDGIFIVAITVSKKEKRIISKAKVNTRGFVYVKKSRDILRESAELVNTT
                     VGNYLQGDHFDWSELKGSVREELSRFLFEQTKRRPAILPVVMEVR"
     gene            complement(26964..27722)
                     /locus_tag="TV188_000089"
     CDS             complement(26964..27722)
                     /locus_tag="TV188_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533490.1"
                     /translation="MRKIIELIHATVEVNNGFDETKAILDDVSLTIYEHDFLTILGGN
                     GAGKSTLFNVIAGTLLLSKGQIKLLGHDVTHLPAEKRASYLSRVFQDPKMGTAPRMTV
                     AENLLIARQRGERRGLSSRRISHYMADFADLVKRVGNGLENHLETPTGLLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSQALMALTDDFVAKDRLTALMITHHMEDALNY
                     GNRLIVMKNGKIIQDLDQKRKSQMTIADYYQLFD"
     gene            complement(27719..28588)
                     /locus_tag="TV188_000090"
     CDS             complement(27719..28588)
                     /locus_tag="TV188_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533491.1"
                     /translation="MIISSVSQGLLWGILGLGIYLTFRILNFPDMTTEGSFPLGGAVA
                     VTLLNLGLNPILATLAAMLAGALAGFATGLLYTKGKIPTLLAGILVMTSCHSIMLMVM
                     GRANLGLHDIKRIQDYLPFAADTNVLVAGLVVATLVIFLLMYFLYTNIGQAYIATGDN
                     RDMAKSFGIHTDRMELMGLAISNALIALSGALVSQQDGYADVSKGIGVIVIGLASIIV
                     GEVLYSTGLTLLERLIAIVVGSILYQFLISVVIALGFNTNYLKLFSAIILALCLMVPV
                     LKKAIIKEASLSR"
     gene            complement(28602..29597)
                     /locus_tag="TV188_000091"
     CDS             complement(28602..29597)
                     /locus_tag="TV188_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1533492.1"
                     /translation="MKHKGLIVTVIALFLMVAASLVLKEGKKQPQLASKRVVKVGILQ
                     LVTHEALDQIAQGIKDELKKHHQPEQKVSITLMNAEGDQSKIQTMSKQLVKTNDIVVG
                     IATPAAQGLAAATKTIPVVMSAISDPVGAKLVKHLDRPEANVTGLSNKVPVRQTVDLI
                     KEMTPQVKRVGVLYASSEDNSISQVKDFTALAEKQGLEVLAYAVPSTNEVTTTMSVMT
                     EKVDAVFIPQDNTIASAFSAVIVASNAAQLPVYSSVDTMVEQGSLASISQSQYQLGVE
                     TARQVLQLMAGKEVSEVPVEVVDDGKPFLNLKAARDLGLMISKDLLKRSDLTGKQ"
     gene            29949..31619
                     /locus_tag="TV188_000092"
     CDS             29949..31619
                     /locus_tag="TV188_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HEL1533493.1"
                     /translation="MSFDGFFLHHLTQELNHSIVNGRIQKVNQPFDNELVLTIRNHRQ
                     TYKLLLSAHPVFGRIQLTQTDFQNPQFPNTFTMIMRKYLQGAIIEGFEQIDNDRIIEM
                     TVSNKNEIGDAIKTTLIIEIMGKHSNIILVDRHENKIIESIKHVGFSQNSYRTILPGS
                     AYIEPPKTTAVNPFTISDIALFEVLQTQELSAKNLQKHFQGLGRDTAQELSSLLTTDK
                     LKRFRDFFQRPSQPSLTQTSFAPVAFSNTLKTFQNLSQLLDYYYHDKAERDRINQQAS
                     DLIHRVQNELEKNRSKLIKQEAELLATENAEDFRQKGELLTTYLSLVPNDQDSVELDN
                     YYTGQKITIALDKALTPNQNAQRYFKKYQKLKEAVKHLSGLIADTQQTIAYFESVDYN
                     LSQATIDEIEDIREELIQAGFVKSRKHNKHHKRKKPEQYLASDGKTIIMVGRNNLQNE
                     ELTFKMAKKGELWFHAKDIPGSHVIIKDNLSPSDEVKTDAAELAAYYSKARLSNLVQV
                     DMIEAKKLHKPSGAKPGFVTYTGQKTLRVTPIESKIQAMKCSPSASSS"
     gene            complement(31708..32946)
                     /locus_tag="TV188_000093"
     CDS             complement(31708..32946)
                     /locus_tag="TV188_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEL1533494.1"
                     /translation="MLNSEKMIASLEQQDLEQAESYFQRALQEDDAETLLALAEYLES
                     IGFLLHAKTIYLQVCEAYPEVNINLAQIAAEDNVIEEAFMYLDRIPEDSADYLSALLV
                     MADLYDLEGLTDVAREKLLQAAELSQEPIVIFGLAEIEMSLEHFSEAIEQYARLDNRH
                     ILELTGISTYQRIGRAYAYLGKFEAAVEFLEKALAIEYDDETVFELATILYDQAAYQK
                     ANLYFKQLETMNADFLGYEYPYAMSLREEHRTEEALRLVQQGLRKNAFDPQLLLLASQ
                     LAFELHDPAGSERYLLRAKEVAVDDEEVIMRLSSLYLDMERFEEVIALEHEEIDHVLT
                     KWNLAKAYQALEQQEKALTIYKDIEGDLKENPDFLQDYAYLLREFGYTDQAVKQAKRY
                     LQQVPDDIHMQGFLDDLRDD"
     gene            complement(32936..34117)
                     /locus_tag="TV188_000094"
     CDS             complement(32936..34117)
                     /locus_tag="TV188_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1533495.1"
                     /translation="MSLHSKPNHHDSLFYKWFLNNQAVMVLLITLLVFLTIFVFTKIS
                     FLFTPILSFLAIIMLPLVISTILYYLTKPLVDMVEKLGPNRTASIFIVFGLVILLFFW
                     AISGFIPMIQDQLRSFVEDLPKYVAKVNLEANKLLENEWLVSYRSNLQDMLTSMSQKA
                     LDYAQSFSKNAIDWAGNFAGAIARITVAIIMSPFILFYFLRDSGHMKNGLVNVLPIKL
                     RQPMARVLGEINKQLSGYVQGQVTVAIVVGLMFSVMFSLVGLNYSITFGIIAGFLNMI
                     PYLGSFLAMIPVVIMGMVQGPLMLIKVLIIFVIEQTIEGRFVAPLVLGNKLSIHPITI
                     MFLLLTAGSMFGVWGVFLVIPVYASVKVVVKELFDWYKDITGLYEEEPTEAERVAEDV
                     K"
     gene            complement(34180..34656)
                     /locus_tag="TV188_000095"
     CDS             complement(34180..34656)
                     /locus_tag="TV188_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1533496.1"
                     /translation="MTKLATICYIDNGEALLLLHRNKKENDVHQGKWISVGGKLEPGE
                     SPDDCARREILEETHLLVKAMDFKGVITFPDFTPGHDWYTYVFKVTDFEGDLIADEES
                     REGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFRYDDHNKLVEKTVTFY"
     gene            complement(34834..35880)
                     /gene="rfbB"
                     /locus_tag="TV188_000096"
     CDS             complement(34834..35880)
                     /gene="rfbB"
                     /locus_tag="TV188_000096"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003002700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEL1533497.1"
                     /translation="MSEYKNIIVTGGAGFIGSNFVHYVYNHHPEVHVTVLDKLTYAGN
                     RANLEEILGDRVELVVGDIADAELVDKLAAKADAIVHYAAESHNDNSLNDPSPFIYTN
                     FVGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTADTNYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSTGVWAILTKGRIGETYLIGADGEKNNKEVLELILDKMGQPKD
                     AYDHVTDRAGHDLRYAIDSTKLRQELGWEPQFTDFSEGLEQTIQWYTDHQDWWRSEKE
                     AVEANYAKTQEVIR"
     gene            complement(36072..36668)
                     /locus_tag="TV188_000097"
     CDS             complement(36072..36668)
                     /locus_tag="TV188_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEL1533498.1"
                     /translation="MTEQFFDKALACREIEAIPGLLEFDIPVRGDNRGWFKENFQKEK
                     MIPLGFPEQFFAAGKLQNNISFSRKHVLRGLHAEPWDKYISVADEGKVLGAWVDLREG
                     DSFGHTYQTVIDASKGIFVPRGVANGFQVLTDKVAYTYLVNDYWALELKQKYAFVNYA
                     DPSLGIAWESLEQAEVSEADKSHPFLEAVKPLRQEDLS"
     gene            complement(36668..37537)
                     /gene="rfbA"
                     /locus_tag="TV188_000098"
     CDS             complement(36668..37537)
                     /gene="rfbA"
                     /locus_tag="TV188_000098"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEL1533499.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPIYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLPRFEELLGDGSEFGISLSYKEQPSPDGLAQAFIIGEEFIGDDRV
                     ALILGDNIYHGNGLTKMLQKAAAKEKGATVFGYQVKDPERFGVVEFDDEMNAISIEEK
                     PAVPKSHFAVTGLYFYDNDVVEIAKSIKPSARGELEITDVNKAYLERGDLSVELMGRG
                     FAWLDTGTHESLLEAAQYIETVQRLQNAQVANLEEIAYRMGYITKEDVYQLAQSLKKN
                     EYGQYLLRLIGEA"
     gene            complement(37594..38703)
                     /locus_tag="TV188_000099"
     CDS             complement(37594..38703)
                     /locus_tag="TV188_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEL1533500.1"
                     /translation="MTTIAIIGAGIVGSSAAYYLKKQGYQQVTIFDDGNGQATKAAAG
                     IICPWFSKRRNKAWYQLARLGADCYQDLIKELQKEGLSTHFYKQTGVYLLKKNEDKLE
                     ELYQLAIRRKQESPLIGDLAIRCRSDIRVDFPDLQGFEQLVWASGAARVDGADLCQCL
                     LEASGYQVVKKRVGISIEKQGYLVDGMVFDRLILAAGAWLPELLEPLGYQVDIRPQKG
                     QLIDYHIANVTTDNYAVVMPEGELDIIPFEHDRLSVGASHENDKGYDLEPDVAVLEAL
                     EQEALTYYPKLSSASDVSYRVGIRAYTRDFSPFFGQVPQLPGVYAASGLGSSGLTLGP
                     LIAQQLIALLLGQKASLDTSQYPIHHYIRRINDKK"
     gene            complement(38758..39546)
                     /locus_tag="TV188_000100"
     CDS             complement(38758..39546)
                     /locus_tag="TV188_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019781659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEL1533501.1"
                     /translation="MKARTIIEKYESYCPLELSMSGDVCGLQIGSLDKEVKRVMITLD
                     VRENTVAEAIAAKVDLIITKHAPIFKGLKDLVSSPQRDIVLELVKHDISVYVSHTNID
                     IVSDGLNDWFCELLGIEQTEVLVETQDGYGIGRVGNVAEQSLEELGLTVKEAFGLDVV
                     RLVRYTGQNPLISRVAICGGSGDKFYQAALAKGAQVYITGDIYYHTAQEMLTEGLLAI
                     DPGHHIESLFIDKLLAKMQAWKKEEGWQVTIMASKASTNPFSHL"
     gene            complement(39536..40222)
                     /locus_tag="TV188_000101"
     CDS             complement(39536..40222)
                     /locus_tag="TV188_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEL1533502.1"
                     /translation="MESHLSKRLRHVASYVPDGAKLLDVGSDHAYLPIFLVETEHIQE
                     AIAGEVVKGPFVSALKNVSQYGLTEHIEVRLANGLAAFEARDAVDCITICGMGGRLIA
                     DILAAGKEKLQGIERLILQPNNREDELRAWLSANAFCISAETIMTENGKYYEIIVAEP
                     GQQSLTDQEQRFGPFLSQERSSVFVAKWQKERDKLVYALSCVPATKPVERASISQKIK
                     AIEEVISHES"
     gene            complement(40296..40958)
                     /gene="nth"
                     /locus_tag="TV188_000102"
     CDS             complement(40296..40958)
                     /gene="nth"
                     /locus_tag="TV188_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEL1533503.1"
                     /translation="MRIGRERLKKVLSIIGEMFPEAKGELNWDQEKPFQLLITVILSA
                     QTTDKAVNKVTPKLWQSYPELSDLAQANVSDVEDHLRTIGLYKNKAKNIIKTAQQLLT
                     QFDGQVPKTHKELESLPGVGRKTANVVLAEIYGVPAIAVDTHVSRIAKRLNISAPDAD
                     VTEIEADLMAKLPKKDWIITHHRLIFFGRYHCLAKHPKCDTCPVQSYCSYYKTTYGKK
                     KV"
     gene            complement(40958..41635)
                     /locus_tag="TV188_000103"
     CDS             complement(40958..41635)
                     /locus_tag="TV188_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEL1533504.1"
                     /translation="MSFLEHYQSGNLVLPTALLFHYKDIFKSSDDFLVWQFFYLQNTT
                     RLDELAPSQIANALGKSVAEVNKAISSLTSQGLLDMKTIELAGEIEIIFDASPVLVTL
                     DQLLARDEKGEHEQQNTNQLKLLVDEFERELGRFLSPMELEDLEKTIHDDQTDLDLVR
                     EALREAVFNGKTNWKYIQAILRNWRKEGITSLRQLEEKKRAREDMTASEVTVSDDFLA
                     AMNLWSN"
     gene            complement(41702..42220)
                     /locus_tag="TV188_000104"
     CDS             complement(41702..42220)
                     /locus_tag="TV188_000104"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEL1533505.1"
                     /translation="MDLTQYIASIENYPKEGITFRDISPLMASGKAYSYAIREIVQYA
                     CDKDIDMIVGPEARGFIIGCPVAVELGIGFAPVRKPGKLPREVISASYEKEYGLDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIDLVEKLGGIVAGCAFLIELDGLNGRQAIG
                     DYDCKVLMHFPG"
     gene            complement(42300..42668)
                     /locus_tag="TV188_000105"
     CDS             complement(42300..42668)
                     /locus_tag="TV188_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533506.1"
                     /translation="MRLWHQDLITRLPRQQLLGQHRECAALRGAGWGRPHATVDYVFA
                     HSLYKLYQYHLLIMQEMQARGYQPDVSWQDKNYRGKSLAAYEDLEEVALTSPIYPEHQ
                     EAYLQECLTNLKEKGIDLDD"
     gene            complement(42677..44887)
                     /gene="recJ"
                     /locus_tag="TV188_000106"
     CDS             complement(42677..44887)
                     /gene="recJ"
                     /locus_tag="TV188_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEL1533507.1"
                     /translation="MITSKYQWTIADKEPDAGFFKLAQAKGLSQTAAKLIYDRGVHTE
                     EELTSFLTADLSQLHDPYLLNDMEKAVHRIRQAIEGLERILVYGDYDADGMTAASIVK
                     ETLEMMGAEPLVYLPNRFTDGYGPNQSVYKYFIEQEQVSLIITVDNGVSGHEAVAFAQ
                     AQGVDVIVTDHHSLPAELPDAFAIIHPEHPAAAYPFQKLAGCGVAFKLASALLETIPV
                     DFLDLVAIGTIADMVSLRGENRILVKNGLAVLKETERLGLQELMKLSEVDLAHFDEDV
                     ISFKLAPQLNALGRLDDPNPAIDLLTGFDDEELHELALMISSKNEERKVLVQEIFAQA
                     MAMLDLDKPVQVLAKSGWHPGVLGIVAGRIMEEIGQTVLVLTIDEGLAKGSARSLESI
                     NIFEALNSNRSLFTAFGGHEGAAGMTLPSDRLEELSELLCQYVAAKGHDGQEKNTLLI
                     NGELDLEALSIDSLNKLLLLAPFGMDNKKPVFYLKDFTIKQARTIGQQQSHLKFKVSK
                     GAVEADVLAFGQGHLIQEYQQSQGLELAVSLAINHWRGHTSLQLMLVDARVTGVQLFD
                     IRARTARAPEHIPTAVEDQQAKVVVIDEVPDDIDALKGLFRHREFEAIYFKNHIKRPY
                     YLTGYGSREQFAKLYKTIYQYPEFDLRHKLTLLSDYLKIEKILLVKMIQIFEELGFVV
                     IEDGLMRVKTDAPKRSIADSVIYQQLKELVKFQELMALGSPQEIYQYLMTSEEK"
     gene            complement(44884..45648)
                     /locus_tag="TV188_000107"
     CDS             complement(44884..45648)
                     /locus_tag="TV188_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1533508.1"
                     /translation="MAQRIILITGASGGLAQAIIRQLPREDYLILLGRSKDRLDSLYQ
                     ARGNKECYEIAIQDPAAIEALVDELYQRHGRIDVLINNAGFGAFKAFDDFSAEEIEAM
                     FRVNSLASIHFARLLGHKMAEQGSGHIMNIVSMAGLIASAKSSIYSATKFAVIGFSNA
                     LRLELAERQVYVTTVNPGPIATSFFEQADPSGQYLASVAGFTLQADTVAKKIIAAIGK
                     KKREINLPISLALAHKCYTLFPTISDYLARKVFNYK"
     gene            complement(45648..46577)
                     /locus_tag="TV188_000108"
     CDS             complement(45648..46577)
                     /locus_tag="TV188_000108"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEL1533509.1"
                     /translation="MELQFLGTGAGQPAKHRNVSSLVLKLLDEINEVWMFDCGEGTQR
                     QILETTIKPRKIKKIFITHLHGDHIFGLPGFLSSRAFQASEEQTDLEIYGPVGIKSYV
                     TNSIRISGSKLPYQIHYHEFDDTSMGKILETDKFIVYAERLAHTIFCMGYRVVQKDLE
                     GTLDAEALRAVGVPFGPLFGKVKNGQDIELEDGTKIFAKDFISEPRKGKIITIIGDTR
                     KTSASVRLAKDADVLVHESTYGKGDERMARNHGHSTNMQAAQIARDAGAKRLLLNHVS
                     ARFLGRDCRQMEKDAATIFENVKVVRDLEEVII"
     gene            complement(46592..47230)
                     /locus_tag="TV188_000109"
     CDS             complement(46592..47230)
                     /locus_tag="TV188_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEL1533510.1"
                     /translation="MTDYIQLAKTYGGFTSLDTVYLQNCLKGLTDQQKLATITPPPSV
                     INAYFAEMYQKQSPKAATDYYFELSRALKLFTSEPSFDEVKPFVRLNLLGQSYGFVFE
                     NEAQEAIVFAEKEQGQPEESLLLELAQIFPQYVVYVEDGRIKMKSCQFEQGEPEDITP
                     EHALLTTIYRFSNEMTLLKGFNSDELLALSQAFKGKKYYQFAQREFMIYLVH"
     gene            complement(47223..48461)
                     /gene="hflX"
                     /locus_tag="TV188_000110"
     CDS             complement(47223..48461)
                     /gene="hflX"
                     /locus_tag="TV188_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEL1533511.1"
                     /translation="MIETKARQERVILLSVVLQAADHAELSMTELASLAKTAGAEVVD
                     CYLQKRERYDSKTFVGSGKLAEIKEMVAANEIDTVIVNNRLTARQNANLEDALGIKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYMLPRLVGQGVMLSRQAGGIGSRGPGESQ
                     LELNRRSIRHQIADIERQLAAVEKNRQTIRDRRMTSDVFNIGLIGYTNAGKSTIMTIL
                     TGDKQYEADELFATLDATTKQIYLQNQFQATLTDTVGFIQDLPTELVAAFKSTLEESR
                     HVDLLLHVIDASDPNHLEHERVVLDILKDLDMLDIPRLAIYNKMDKTASLTATVFPNV
                     RLSARDKNSRSLLRQLLIDQIRDMFEPFSIKLCQDQAYKCYDLNRLALLEPYSFDKEI
                     EEISGYIAPKNKWRLEEFYD"
     gene            complement(48546..49436)
                     /gene="miaA"
                     /locus_tag="TV188_000111"
     CDS             complement(48546..49436)
                     /gene="miaA"
                     /locus_tag="TV188_000111"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEL1533512.1"
                     /translation="MTKEKIIVIVGPTAVGKTALGIALAGAFNGEIISGDSQQVYRHL
                     DIGTAKASAREQALAVHHLIDIREVTESYSAFDFVQDAKRAIEDIVSRGKLPIIVGGT
                     GLYLQSLLEGYHLGGDLDQKELLAYRQQLETLTDTELYQLLASKGIHLDQVNRRRAIR
                     SLELNQFARDLENQEAPYNPLIIGLTDEREVIYERINKRVDLMMASGLLEEARWLFEQ
                     YPAVQASRGIGYKELFPYFQGQASLEEATATLKQQTRRFAKRQLTWFRNRMAVRFDSI
                     SESSYPQAIYDRVERFLKEP"
     gene            49569..49745
                     /locus_tag="TV188_000112"
     CDS             49569..49745
                     /locus_tag="TV188_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEL1533513.1"
                     /translation="MAKKHGFAKGLATGVLATAATVAGAVFAVKKTIIDPEEEKAAFV
                     EENRKKAARRRVAR"
     gene            complement(49901..50538)
                     /locus_tag="TV188_000113"
                     /pseudo
     CDS             complement(49901..50538)
                     /locus_tag="TV188_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
     gene            complement(50695..52959)
                     /gene="glgP"
                     /locus_tag="TV188_000114"
     CDS             complement(50695..52959)
                     /gene="glgP"
                     /locus_tag="TV188_000114"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEL1533514.1"
                     /translation="MKRFTDYTEMTLGKSLASASNEEIYLSLLSYLKEEASKKAKNTA
                     KRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGL
                     GRLASCFIDSISSLGINGEGVGLNYHCGLFKQVFRHNEQTAEPNFWIEDDSWLVPTDI
                     SYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTDIAKN
                     LTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLLIDEALERGSNLHDLADYAYVQINDT
                     HPSMVIPELIRLLTQKHGFDFDEAVSVVQKMVGYTNHTILAEALEKWPLDFLNEVVPQ
                     LVTIIEQLDALVRARVSDPAVQIIDETGRVHMAHMDIHFATSVNGVAALHTEILKNSE
                     LKAFYELYPEKFNNKTNGITFRRWLEFANQELADYIKELIGDAYLTDATRLEKLMAFA
                     EDQAVHARLAEIKHHNKVALKRYLKDNKGIELDEHSIIDTQIKRFHEYKRQQMNALYV
                     IHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNV
                     HLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIA
                     ELAGMDNIYTFGKDSDTIIDLYATGGYVSKDYYDAHPAIKEAVNFIISPELLELGNEE
                     RLDRLYKELISKDWFMTLIDLEEYIAVKEQMLADYDNQDLWLTKVVHNIAKAGFFSSD
                     RTIEQYNQDIWHSY"
     gene            complement(52985..54487)
                     /gene="malQ"
                     /locus_tag="TV188_000115"
     CDS             complement(52985..54487)
                     /gene="malQ"
                     /locus_tag="TV188_000115"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEL1533515.1"
                     /translation="MTKRASGILMHISSLPGRFGIGSFGKEAFEFVDFLKETKQTYWQ
                     ILPLTTTSFGDSPYQSFSAIAGNTHFIDLELLAKDGYLQEADYAAVDFGSNPESVDYA
                     QVFQARRPLLEKAVQAFVSTEEGLRQLAEFEATASWLNDFAEFMAIKEHFDHKALQEW
                     DDRAIVKREEAALLHYRKLLAKGITYHKVCQYFFYQQWLALKTYANQNGITIIGDMPI
                     YVSADSVEVWTMPELFKVDADKKPIYIAGVPADGFSEDGQLWGNPIYNWESHEQTGFA
                     WWIHRIKESFKLYDKLRIDHFKGFSDFWEIPGGDVTAKNGHWESAPGIALFKAVREAL
                     GELPIIAENLGYIDEKAEQLLASTGFPGMKILEFGLFDVTSQSFDLPHNYDHNCIVYT
                     GTHDNEVVNGWYEHLSAEQVEFVNHYIHKAAAESITKAMLRTIFATVCDTAILCMQDL
                     LDKSADSRMNMPNTVGGNWQWRMLEDDIKAEHKAYLIHLTELYGRANNHH"
     gene            complement(54694..55716)
                     /locus_tag="TV188_000116"
     CDS             complement(54694..55716)
                     /locus_tag="TV188_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1533516.1"
                     /translation="MVTIKDVALKAGVNPSTVSRVLKDNRSISQKTKEKVRRAMSELG
                     YVPNVAAQMLASGLTHNIGLVFPPIITNDRLSDPFFMEILSTITNEAKKHHFTVSIAT
                     GMSVEDLLSQVKLMHLQKRVDGFIILYSEQEDPVRGYLMTNQIPFVIVGAPEGDENKI
                     TYIDNDNQLMAKTAVDHLYQKGHRQILFITDDMEAEVASERYIGYLKGCLKLSLENKP
                     MLLFDRKDPISIEKVIETIRSFKATALIVIGDVLSVRMVQLLSFYDIKVPDDISIITF
                     NNSSYSKLIHPYLTTFDINVENLGRTSFRQLLDIINANEQTLSQKILVPFSLKKRESV
                     RDINAK"
     gene            55963..57216
                     /locus_tag="TV188_000117"
     CDS             55963..57216
                     /locus_tag="TV188_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1533517.1"
                     /translation="MKSWQKVIVSGASLTLASALLVGCASGSKDKTETASGTDSKTIK
                     LWVPTGAKKSYTDVVAKFEKDSGYKVKVIESEDPKAQEKIKKDASTAADVFSLPHDQL
                     GQLVESGIIQEVPEEYTKEIADTATDQAILGAQYKGKTYAFPFGIESQVLFYNKTKLA
                     ADDVASYDTITSKATFGGTFKQANAYATGPLFMSVGNTLFGESGEDTKGTNWGNEKGV
                     AVLKWISDQASNKGFVNLDANNVMSQFGDGSVASFESGPWDYEAAQKAIGKENLGVAV
                     YPKVTIGGETVQQKAFLGVKLYAVNQAPAKGDTKRIAASYKLASYLTNAESQENQFKT
                     RNIVPANKTVQASEAVQSNELAKTVITMGSSSDYTVVMPKLSQMGTFWTESAAILSDA
                     FNGKIKEGDYLAKLQQFDKDIAATK"
     gene            57516..58877
                     /locus_tag="TV188_000118"
     CDS             57516..58877
                     /locus_tag="TV188_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1533518.1"
                     /translation="MTQAGLASQVTVKEALTKGSFDIKLSAIIMGFANFANKQFVKGT
                     LFLLSEVVFFIAFVSQIIPAIGGLITLGTQTQGMTTKTIDGISIQVAVDGDNSMLMLI
                     FGLASLIFCLLFAYIYWCNLKSARHLYMLKQEGAKIPSFKEDFVSLANGRFHMTLMTI
                     PLIGVLLFTVLPLIYMICLAFTNFDHNHLPPKSLFDWVGLSNFGNVLSGRMAGTFFPV
                     FSWTLIWAVFATVTNFFFGIILALLINTKGLKLKKMWRTFFVITIAVPQFISLLIMRN
                     LLNDQGPLNALLSKLGLIHHSLPFLSDPIWAKFSIIFVNMWIGIPFTMLIATGIIMNL
                     PSEQIEAAEIDGASKFQVFKSITFPQILIIMTPNLIQQFIGNINNFNVIYLLTGGGPT
                     NSAYYQAGTTDLLVTWLYKLTVTAADYNLASVIGILIFTVSAIFSLLAYTRTASYKEG
                     AAK"
     gene            58877..59713
                     /locus_tag="TV188_000119"
     CDS             58877..59713
                     /locus_tag="TV188_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1533519.1"
                     /translation="MKNKRRFQLGLVYAILTVLSIIWLLPIAWVVLTSFRAEGTAYVD
                     YFLPKHLTLDHYIKLFTNETFPFGRWFVNTFVVAIFTCIISTFITVAMAYSLSRIKFK
                     FRNRFLKLALVLNMFPGFMSMIAIYYILKALGLTQSLTALVLVYSAGAALGFYIAKGF
                     FDTIPYSLDESAMIDGATRMDIFFKITLPLSKPIIVYTALLAFMGPWVDFIFAQVILG
                     DATSRYTVAIGLFSMLQPDTINDWFMAFTAGSVLIAIPITLLFMFMQKYYVEGVTGGS
                     VK"
BASE COUNT        17470 a        14025 c        11157 g        17102 t
ORIGIN      
        1 attcgtcata tttttacttt cattttcttt tcttggtcaa aaagaagtaa cggtatcgtc
       61 acgaggtgaa attatgccta caaaagtcat tgcatcaata cagtcaacta gcaacaatgc
      121 tatcgttaaa aataatctta aagaaaacca actcgttaaa aaaggaaaac gtttaatcaa
      181 atataaagaa accattgaga gttctcaaaa gaattctcta gaatcacaat taaatacgtt
      241 gaataaacaa aaagttggtt tagagacatt gaaagaaagt ctcaaacaag gaacgaacct
      301 cttaccacaa aatgatgaat ttggtcttgc tgacaccttc aacaacttta taaatcagtc
      361 tcaagagatt aaacttggta tcgctaaaat aaatacagaa gtatccaatc aatccacact
      421 tgcaaataac acccttgctg caattgatac tcaaatcaat actataaacc agcagatttc
      481 agaatatgaa gatcttcgtc aagctatctc aaatcataac acaatcttac caactggtaa
      541 tcctcatcaa gatattctca ataattatct gtctcaatca caagaagaat aaacttccac
      601 gtctaaccag tttatctctc agattaacca gactatttca ggtttagaat catccctctc
      661 tgggcttagc attcaaagag caggtactgg tagtagtgca acatacgata acagttcaga
      721 aaccaaagtt gaagtcttga ggactcaatt tctacagaat gcttcacaac agctgtcaac
      781 catcgacagt caaatcactg aacttaaagc tcagctagaa caagcaagtg tatagttaga
      841 cactaatgtt gttttagcac cagaaaccag gattattcat ctaaataatg aatacgaggg
      901 gaaaagtctt atcccaaatg gtagtgatat tgccaaaatc tatcctaata ttactcaaac
      961 tagaaaagct ctgattacat actttgtaac ttctgattat gtttctctcc ttaaaaaagg
     1021 tcaaactgtt cgtctaaatc ttcaaaaagt gagaaaacag tccatcactg ttaatggaaa
     1081 aatttctact attgataaaa cagcaacaaa aacagaacaa ggtaatcttt tcaagattac
     1141 aactcttgcc aaactccctt ccaaggatag ctacttgata aaatatggtg cacagggtcg
     1201 tgttacaagt gttatcgcta aaaaatccta cttcgacttt tataagaata aactgttgtc
     1261 aaatcatgat taaaccattc cggacgtttc gatgaccatt taggatttag agaaataata
     1321 tattgatctt aaattataat attagaaaaa agaaggaggt ccacaaatgg aaaaacaaaa
     1381 ttcactcact caatttcaag aactaaattc atccgaactc aatcaaataa caggtggaga
     1441 ttggtggtca gagatattaa attttaatcg ctctcaaaaa tataaacata cctccgtggg
     1501 ttctaataat attattgtct aacatatact tagtattgta ataatagttt ttttagtaga
     1561 aatcataacc acccgtccaa caggtggttt gaatagggac tataaaccca tataactagc
     1621 cagcgcctaa agacgctggc tttcactttg ttcaaaccac attgctattg actcgtcact
     1681 tgcctctcaa agaagtattt gtatcactta cccttatctc taaagggatc ctcatattct
     1741 tttacactca gtttatctag tgctatgtca tgtttttctt gttcttgaat atattttttt
     1801 attgtagctt catttaatcc aaccgtacta atataatagc cttctgccca aaagtgtcga
     1861 ttaccaaatt tgtatttcag attggcgtgc ttgtcgaaca tcataagcgt actcttacct
     1921 tttaaatatc ctataaaact tgaaacactt attctgggtg gaatgcttac taacacgtgt
     1981 acgtgatctg gcatcagatg tccttctata tatttctaca cctttatagc tacataatct
     2041 ttgaaaaatt tctcccaaac tgcctcgata ttgattatag attacttttc gtctatactt
     2101 aggggtgaac acaatgtgat atttacaatg ctactttgtg tgcgataaac tgtggggctt
     2161 ttgtgccata tttttactcc tttcgcttta caattggctt gaacacctat attgtagcgc
     2221 gtttggagtt tttttgtagt ataacgttcg atgcgtaccc gcatagcggg ggatttttgt
     2281 ttcgcaccta cggagcgaaa cggactaaag tcactaagtc ataaccacgc gtaaaaacgg
     2341 gtggcttgta caccggctat aagccgtttc tctccagcga cgtctaaaga cgttcgctga
     2401 acttcgttca ggttagtgct atgattactt gactaatgcc cgtaaaaacg ggcttttatc
     2461 ttgttttaaa actgccatct gaaaatggat cttcatattc tttaacactc aacttatcaa
     2521 gtgcaatgtc atttttctcc tgctcgcgaa tatatttcgc taccgtcctt ttgttcagtc
     2581 caacggtact aacatagtag cctctagccc aaaactttcg atttccatac ttatatttta
     2641 aattagcgtg tttatcaaat atcatgagag cacttttact tttcaaatac cccatgaaat
     2701 cggaaatcga aagttttgga ggtagcaaga cgagcatatg aacatgatct ggcatcatat
     2761 gtccctcaat gatttccacg cccttgtatt gacataggtg acggaaaata tcaattaagt
     2821 cctgtctaat tttgtagtaa atggattttc tgcggtactt tggtgtgaaa actatgtgat
     2881 atttgcacat ccatttggta tgtgataaac tgtaactggt tttagccatc tctttttcct
     2941 ccttgatcta acctgaacaa ttagattata acaggaaaaa gaaatggaag ctcaaagcct
     3001 tgtcagccac cagcatagct ggtggttttc ttgtttttct ctacgagaaa aactggctcg
     3061 aagccataat aaaaataaaa accctgccaa aaaatctttg gtagggtttt tagcaggaaa
     3121 ccaaatcaat ttatcagttt ctctaaatcg ctctaagcaa tcattaaacc ttgatttact
     3181 aggcttccgc aatcaaattg cgatactcta ttatttaaga gtgatagttg ctccagcttc
     3241 ttcaagctta gctttgattt cttctgcttc tgctgctgca acaccttctt tgatgttagc
     3301 aggtgcgccg tcaacaagac ctttagcttc tttaagtcca agacctgtga tttcacgaac
     3361 tgccttgata acaccaactt ttttgtcacc agcagatgtc aactcaacgt caaatgaatc
     3421 cttagtagct tcttcagcac caccagcagc agctacagct acaggagcag ctgcagtcac
     3481 accgaattct tcttcgatag cttttacaag atcgttaagc tcaaggattg aagcttcttt
     3541 aatttcagca ataatgtttt caatgtttaa tgccattgtc atttcctcca aatagttata
     3601 ttaaataatg atttgtagct ctaggctacc tctaaaggcc ttacgcagcg ccttctttgc
     3661 tttctgcaac agccttgaca gcgtatgcaa cgttgcggac tggagcttga agtacagaaa
     3721 gaagcataga aagcattcct tcgcggtttg gcaatgctgc aagtgcttga atttcctctt
     3781 ttgaagaaac aacaccttcg atagcaccac ctttaatctc aagtgcttca gcagttttag
     3841 caaagtcgtt gatgacttta gctggtgcga taacatcttc atttgaaaat gctactgcag
     3901 atggtcctac gaatatatct tttagctcgt caagacctgc tttttcagct gcacgagtca
     3961 agattgagtt tttgataacc ttgaactcaa cgccactttc acgaagtgaa cgacgaagaa
     4021 cagtatcttg atcaactgta agaccacgtg aatctacaac aacgatactt acagctgctt
     4081 tcattttctc agcgataagc tcaacttgtt cagctttttt agcgataatt gcttcactca
     4141 ttagttttac ctccgttttt atttttgggc taggcacaaa aaaatcgcac ctaaacctag
     4201 acacgaaagt acaaatacgt tatcttcaat aatgacgttt tgtgcctcgg caggaatatt
     4261 atgagcacgc tcccctgctg tcttaggtca gttttattca aaaccatagt tagtatagcc
     4321 tttttaaatg actttgtcaa cctatttttt agaaaatctt aaataaaaaa ggaaagctct
     4381 tggctttccg ctaaatagat ctgattagtg gctcaaaagc gcctcctaac ttaagcctaa
     4441 tgataagcaa cttgtgacga ttgattgcta taacttagcc cgatcaagct ccacagtatc
     4501 atctcataaa taaagaagaa caaggcaaag caatgcccaa aaaaggcctc tggcaaaatc
     4561 caaatgacag gatctgtcag cggatcaaac aaccagcttg aatctcctac aaagagaatt
     4621 tgatgaaaaa gggtaaagaa ctgatcaaag ccaatcatta aagcaaagca agcaatcaca
     4681 attggcaata aggctgctgc tattagccct cttcgaagca gcataaccct tccttttttg
     4741 atgctctgat aaaaatagat aatggttggc aacataagca ggctaaagat cagctgtgtt
     4801 atatgaaaca gcattttcac atctgtaaaa tgctttagac cagctcttga tgctgaaaag
     4861 ctggctagct ttagctcacg aacaaaagga ttggttaagt aagtcagcaa tatattatag
     4921 ttgtggagaa tagacttttt gcacatcaaa actgcctgct ctagttgcaa ataatcaacc
     4981 tcaatcggat aaagcagcca agataaatag atagttatca aaactgccag tgctagtagc
     5041 caaagccaac tggcaatgaa cttgcctttt tcaatcataa tagctcccac tcatctaagc
     5101 tagccaagac atgatcaggc ttaattggaa ggcttggaac ctcttttgcc tttgtaaagc
     5161 cggttgttac tagaatagtt gccatatcat tttgaattcc tgccatgata tctgtcaggt
     5221 aattgtctcc aaccatagcc acctcagaac gtggtacctt taagatctct agggctttat
     5281 tcatgataat cgcatttggc tttcctataa atactggctt cactctagtt gctgcctcaa
     5341 ggagcgcatt taaagcgcca gcacctggca ttagcccacg ctctgttgga atatttaagt
     5401 caggattggt cccaataaac aaggctcctt tttgaatggc aagtgttgca attgataaca
     5461 tttcataggt aacctcagta tctaagccaa caacaacata ggctggattt tctgtatcct
     5521 cggtatagcc tgcctctgca atggcagact ttaagccagt ctcgccaatc acataggctg
     5581 ttttgcctcg attcatatca ttcatgtaat caacggttgc cattgtagcg gtgtaaatgg
     5641 tttcaagacc tgtatgaacg ttaaattgat tggctagcat ttcctgaacc atttcaggtg
     5701 ttcttgtggt gttgttggta actaagagat aagggatacc tttttcctgt aaacgcttga
     5761 taaagcgctc accagccggg atacgatttt tcccttgata gatggttcca tctaaatcaa
     5821 ttaaataagc tttatagggc actaatttgt ctcactttct ttagtcgtta taggctgcca
     5881 tttgataatg gcctgcgcat taagctggcc tgatgacctg atctcatggt aggaggtcaa
     5941 atgctctaga tgatagcctg aggttatttg agtgctgggc ctcacctctt tgatataggt
     6001 caaggtaagg tggcaaggtc tgtggtgtaa taaaaattca tatcccaaaa cgtcatacat
     6061 ccaatccaaa tacttactat tattggcatg accattcata tcaatgtcaa aataacgaac
     6121 ctgataagct tgaaccatag gatcctgaag ctcatctatt ttgataggac gcttgatttt
     6181 cttaacaaag tcagcctgat aaggcaccac caaatcatct ggtatcgcag ctgccttacg
     6241 tgtttgagga tttagcaggg caaaatgaga taaaatggtc atgatggcat gacctgcctg
     6301 atcataaatg tgaaattgcc ggtaacaaaa taatttattg taagaaatag cttgcgtttc
     6361 aatggttact gtttccccaa accttggcat acgatcaatc gttacatcat aatccgtaac
     6421 aacccaaatc aagccatatt gctgaagtaa cacctcattg cctcgtccaa tttcagctga
     6481 ttgtcttgct gataccatta agcaatgtgc taataaaagg ggcagcttga catcagcctt
     6541 aacatcacaa aaatcaaaag acagcttaag gctttcgcta taccttaatc ccataacaca
     6601 cctcctaatc taagatgaat ttttcagcga cagaatcacc taaaaagagg ccttttttgg
     6661 tcattctgat aaagtccttg tcctctacca aaagcccctg attctgaagc tctctcacaa
     6721 caggaccata gcgtgactca aatgataggc caaatttttc ttgaaaccga ctgactgata
     6781 ctcctgattt ttttcgcaga ccaagaaaaa gctcctcctc catcatctcc tccttggtga
     6841 gcacttcctc acttaaccta gcatttccat ctgctactgc ctttaggtaa tgctgaatag
     6901 gaacccggtt gcggtaacga atcccatcaa gatagccaga agcccctgcg ccacagccaa
     6961 aatactcatc attattccaa tacatcagat tgtgcctgct ttcaaagcca ggcttagtaa
     7021 aattagaaat ttcgtaatgc tcaaagccac tggcttccat ttcagaaata atatactcaa
     7081 acatctcagc ttccaaatcc tcagtgggca aatggagctt gccacgacgc attttgttca
     7141 taaaaacagt gtgatgctct aggataaggc tatacaggct aaggtgagga atatctaaag
     7201 caagtgcctt agccacattt tccttgacct gctgcatggt ctgtccaggc aaagcataaa
     7261 tgagatcgat agacatattt tgaaagcctg cctccttaag actagcaatg gtcgtataaa
     7321 tctgagcctc agtatgactg cgtccaatct gctttaattg cttgtcatta aaagtttgaa
     7381 cgcctaggga aatccgattg acagccgatt gccttaatac tgcaatctta tcctcagtca
     7441 aatcacctgg attggcctcg atggtaaatt cttcaagctg gtctagctgt aggtgctgct
     7501 gcaaatggct cagcaaataa tcaagctgat tggctgttat ggctgttggt gttccaccgc
     7561 caatataaag tgtcttcaag gagctgatct gataggattc aaattcctta atcagtgcct
     7621 ctaggtaggc atcgacaggc tgatttttga taaatacctt agaaaaatca caatagtagc
     7681 aaatttgtgt gcaaaaagga atatgcacat aggctgaggt tggttttttt gacatggtaa
     7741 tattatatca ttttagctca gaaattcatg ccaagtgatt agctttttga catgtactaa
     7801 cctaaggctg cttctttttc tccattctca caaaggaatg actactccca ttagcatact
     7861 gctcaaagct tgaggttggc tgatagccca ttttttggta gaggctttgt gcgcctttat
     7921 taaagctagc gacatttaaa acataggttt cttgcggata agtagtgcta gcaaaggctt
     7981 caatgctgcc caaaaaagaa acaccatctt cctgaccagt agtatcaggg gccataccaa
     8041 gaccaatctc aagctctgat tcctgttcaa aaaagctggc aaagccaaaa agaacaccat
     8101 tgcgaagcac ttgaaagtaa tgctctccac gcgccttggg tgacaatatt gactgatagt
     8161 cctcaggatc agcagtcatg ctatagcact cataagctgg gctatagatc cagtcatgcg
     8221 caatgatttc agcactatgc tgtgtcatcg gcatcaggta aaaagaagac tcagacaata
     8281 agcgatgaaa ggtcttgttg atatgcttta tgcgacgccg ctgcacatca ggctgatctg
     8341 tttgataaat gtaattagca tagccctcct gatattctgg aatcattgtc aaatacagct
     8401 tttgggtcaa ctcatcaagc tgactagcaa tcctatccac tctatgcttt atcatattac
     8461 ctccaattct aatgctgctt gatagcataa aaagtgccga agcaacgaca ctttttctag
     8521 attaatcaag gccaatttcc gcacgaacaa ccgctgcaat ggtatcaaca taatagtcaa
     8581 cttcttcatt gcttggtgcc tctgccatca cacgcaacaa tggctctgtg ccgctaggcc
     8641 ttaccaaaat gcgaccatta ccagccattt ctccttccat ctgagcaata acctcagcaa
     8701 tagcaggcac ttccatagca cgctccttca tgctgttgtc aacacgaata ttaacaagct
     8761 tttgtgggta aatagtgacc tcactggcca attcggagag agttttacct gtctccttca
     8821 tgattttggt gagctgaaca gctgtcagtt gaccatcacc agttgtattg taatccatga
     8881 taatgacatg ccctgattgc tcaccaccaa gattgtagcc gaactgacgc atctcctcaa
     8941 caacgtaacg atcaccaaca gctgttacct tcttatgaat gccacagcta tctaatgcct
     9001 tgtgaaaacc aaggttagac atcactgttg tcacaatcgt atttttagct agcaagccct
     9061 tctcagaaag atacttgcct atgataaaca tgatcttgtc gccatcaaca atagcaccat
     9121 tttcatcaac agcaattaaa cgatcactat cgccatcaaa agccaatcca atatcagagg
     9181 ctgtttctgt caccaagtcc tgaagctttt cagggtgtgt agagccgata ccatcattaa
     9241 tgtttaatcc atttggattc tcaccaataa ctgtaatgtc tgcatttaaa tctaaaaaga
     9301 cattacgagc tgaaacagaa gctgcaccgt tagcagtatc aagagctatc tttaaaccgt
     9361 ctaaatctgc tccagtagta accaagaatc tctcgtactt gcgcaagcct tctggataat
     9421 caaccaaggc tcctaagccc tccgcacttg gacgtggtag gaggtcctct ttggcatcta
     9481 agagcgcttc gatttctagc tcttgctcat cagccaattt aaagccatca ctcccaaaaa
     9541 acttaatgcc attgtcaaga gcaggattgt gactagctga aatcatgaca ccagcactag
     9601 ccttttctgt acggaccaaa taggacacac caggagttgc aagaacacca agcttataga
     9661 cctctatccc aacagaaagc aagccagcaa tcagggctgc ctctagcatt tcaccagaga
     9721 tacgggtgtc acgagcgaca aaaactctag gcctttcagt ctcatgctga cttagcacat
     9781 aaccaccgaa ccgaccaagc ttaaaagcaa gctctggggt caactctaca ttagcctcgc
     9841 ctcgaacacc atccgttcca aaatattttc ccataattta tatcagctaa acgcttcctc
     9901 cattccattt tcctagctat tatgctttat tttttaattg ttgtcaactg aacggttact
     9961 accgaaggct ctatagaaac ctgatttgaa accaagctga ccgttttgct cgtgtttttg
    10021 gtgacgtcag aaatattgac ctctgccacc acctcatcaa tagtttcaag gacctcccga
    10081 ctaccagaaa taacagcggt ctgcttggag agcttatact ggatatctga cagactgtca
    10141 tccattagtc caactgcctc gactcgaata ggaactgatt tggtgatttt tttgacagaa
    10201 actgacaaat tagccttggc tggatcgatc gcactagcta aaatggtacc atcggcagct
    10261 actgcctgca gggttactcg gctgctataa ttagcatcta gcacctgatc atcaggtaat
    10321 ttagcgacaa catgatctat caaggcaata gtagactcat cacttgtgac ctcaaccttg
    10381 tcaatacctg tttcaatttt gctaatctca tagcccttag ccagctgctt actatcgacg
    10441 ctgccacgca ccggaaaggt ctttgttttc ttatttccaa tcgttaccga aatcttatca
    10501 ggagaaacag ttgctgtcac accagtaggt agattgataa cctttagggt caccgttgca
    10561 gtacctggct tactctttgt tagatcagct acgatcttaa agcttctagt gtcactgttt
    10621 acctctgaat ccagctttat gcggttggta gaggtcagat aaacctctgc accgtaagaa
    10681 tagccgctga tgaagtactg atcactatca tacttgatat caataggaac gtcctttaag
    10741 ctatgggtgt aggtttcaat agggctataa atttgagaat tagaatgatt atgactgcta
    10801 gaagcagcgg tcaaaaaaag aataatcgca aaaaagattg acactaagcc cagcccaaga
    10861 cgactattta aaaacctctt catttagctt tgcctcctaa gattttttta taccaaggta
    10921 atgtcgcacc gggctcattc atcaaatgag tcttgagaac cgcctcaagc tcttctgttg
    10981 aaaggtcgtg taaaaattga cccttacgag cgatagagac agctcctgtc tcctcagaaa
    11041 caattatcgt tacagcatca gaattttctg aaagtccaat tgctgctctg tgacgtgttc
    11101 caaattcttt ggaaatcgac attgattcag acaaggggag ataagcacag gctgcagcaa
    11161 ttttattgtt agccacaatg accgcaccat catgcagcgg tgtgtttggg ataaagatat
    11221 tgatcaatag ctgactagaa atatcagcat ttaggggaat tcctgttgcg atatattcct
    11281 gcaaggtctg cgtttgctca atagcaatca gagcaccaat cttccgcggt cccatataag
    11341 caactgattt taagagcgca tcaaccagca tctcctcatc actcaagctt tgcttttgca
    11401 aaaatacctg tgttgatcgg ccaaattttt caagccccgc tcgaatttcc ggagcaaaaa
    11461 tcaccacacc tgcaatcact ccataggtga tgacctgatt catcagatag gttatagtcg
    11521 taaaccctat ccactcggca atcacacgaa tgatgataaa gaatataacc ccttgtacca
    11581 aggacatgat cttagttcct gccaaggatt taataaaacg gtaaatcaaa taggctacta
    11641 ttaaaatatc cagcaaatga accaccaaca tcaaggggtc atcaatcagg cttagtaaaa
    11701 attttgtgtc aatacttgat aaattactca tacaattctc atttctatgt cagatagata
    11761 cctctaacat tatatcacgt ttcaagatgt tttccctatc taaaatttaa gaacttatgt
    11821 taaaatatta acatgaaact aaagacacta ctcgctatag cagccggaag gactgcgcag
    11881 ctcattttaa ataaaatcgg aagaggctca acctaccccg gacgattggc cttgatgtgg
    11941 gataaggata ttttagacac acttgccaag gactatgaga ttgttgttgt gacagggaca
    12001 aatgggaaaa ccttaaccac agctctaact gttggtatcc taaaagaagc ctttggtgag
    12061 gttttgacta atccaagtgg cgccaacatg atgacaggga ttacctctgc ctttttatct
    12121 gctaaaagaa aaaaaacagg caagcctatt gccgtcttag agattgatga ggcaagcctt
    12181 gcaagggtaa caacatacat taagccaagt ctttttgttt acactaatat ctttcgagac
    12241 cagatggatc gctacggtga gatttacacc acctatcaga tgattgttga tggtgctagt
    12301 caagcgccga aggcaaccat tctagctaac ggtgatagcc ctatctttgc ctcaaaggac
    12361 ctggttaatc ctgttaaata ttatggcttt gacacaccta agcatgagcc acgcctagct
    12421 cactacaaca ctgaaggcat tttgtgccca aaatgtgaac agattctccg ttatcgtctc
    12481 aacacctatg ctaatctagg agactatacc tgcttaaatt gtgatttcca aaggcctaag
    12541 ttggattaca agctaacgca attaaccagc attacccatc atagctcagc ctttgtgatt
    12601 gacgatcaga cttatcgcat aaatgttgga ggactctata acatctataa tgccctcgca
    12661 gctgttgctg ttgctgagtt ttttggcatt tctgctgatc agattaaggc tggcttcaat
    12721 aaaagcaagg ctgtttttgg tcgtcaggaa accttctcca tcaacggtaa agcctgtacg
    12781 ctggttctca ttaaaaaccc tgtgggtgct agtcaggcac tagaaatgct gcgcctagcc
    12841 gattatccct ttagcctatc tgtgctttta aatgctgatt atgctgacgg tattgacaca
    12901 agctggattt gggatgctga ttttgaattg attaatcaaa tggacattac tgagatcaac
    12961 gccggtgggg ttcggcattc tgaaattgca agacgcttac gagtgacagg ctttgatgag
    13021 gctaaaatca catcattcga taagcttgaa ggtatcatgc aagccattga aaaccaagag
    13081 gctgagcatg cctatatcct agcgacctat actgctatgc tagcatttcg tgagctgctt
    13141 gccagccgcc acattgtcga aaaggagatg atctaatgac ctatacctcg ctacaatctc
    13201 cggaaaatcg cgattatcaa tacgaccttc atattgctca cctttatggt aatttgatga
    13261 atacctatgg cgataacggc aatgtcttga tgttgaagta tgtcgctgaa aagctaggcg
    13321 ctaaggttag agttgatatt gtatccattg gggatacctt tgaccaagat gattatgaca
    13381 ttgttttctt tggtggtggt caagattatg agcaagccat tgttgctaga gatttgccat
    13441 caaaaaaaga ggccttagca gcctatattc accaaaataa ggtactcctt gccatttgtg
    13501 gtggctttca gctgctggga cagtactata ttcaagccaa tggccttaaa atcaatggca
    13561 ttggggttat gggacattat accttaaacc aagataataa ccgctttatc ggaggcatta
    13621 aaattcacaa tgatgacttt gacgaaacct actatggctt tgaaaatcat caaggacgga
    13681 cctttttatc tgacgatgaa aagcctcttg gacgtgtcat ttatggaaat ggtaataata
    13741 aagaggacca aactgagggc gtccactata aaaacgttta cggcagctac tttcatggac
    13801 caatcctttc gcgtaatgtc agcctggcct atcgcctagt cacaactgct ctcaaagaaa
    13861 aatatggctc gactgtttcc ttagcggcct atgataagat cttacagcat gagacctcag
    13921 aggaatacgc tgatgttaaa agcaaggcta gctttgacag ttaagtcctt ctcatagcct
    13981 gattaaacca caacagacat gcaaaacagt tattcccgaa tgaaaatata gatttaaata
    14041 gacaccctca atgtttttcc tatcataaaa tccataaaag ataagacata ttcttgcaat
    14101 aactgaacat tgaaagacag aaagctttct gtccttacta aacatctttc atgcgtctgt
    14161 cgtgctgatc aagcgagata accccaaaaa agtgctagca cagtaacaaa atggctatga
    14221 ccatatgtct gtgcagctct actgtcactg catagacagg ctagagggga cgccctactt
    14281 ggttcagcga tctaggggta ggtctagctt gtttgtgctg agtctgtttc ggtagcaaag
    14341 attgaatcct gctataagat actctcaaaa agattaaccc aaaagccttg caacacattt
    14401 aacgttttta gggataagta ccgatatgca gacacatagc aggagatcta tgtgtctggt
    14461 accaaaggac acaaaaaact aaagtaacac actaaaagcc acatgatacc catttgatag
    14521 ggggcgtcat gtggcttttt tctatctcac tgttcattac aaaaagccaa accagcttct
    14581 ttttgcatta ggcaacaatg gcctttgcca cctcttctac tgtcatacgt gagaaatatt
    14641 gtgttgtatc aatggtttga agacgctcaa gcacatcagc atactcgtat ttgcaaccaa
    14701 tgagtaggct ttcaatatcc tgcacgtcct taataccaaa gaaatcaccg tagatcttaa
    14761 gattcttaat aacagaattt tcaacattag caaaggttga gattttaccg gcagggtagc
    14821 gaacattacg ttcaatcgtg tattcaggtg cctttccata ggtccaatcc cagctcccaa
    14881 attgctcctc agccgattgt tgaatcttag ccagctcgtc ctctgacaag acgtattctg
    14941 tcatgtctgg ataggtctcc ttcattttaa ccaaaatctt gtctgaaaat gcttctacgc
    15001 tgattttttc tggcagctca tttaaaatat tggtcacgcg ggctcgtaca gatttgactc
    15061 ctttggactc aatcttatcc ttactgacct tgagcgcatc accaagaaca gtcatatcca
    15121 catcaaacaa gagacagcca tgatgcatca tacgtccctt ataataggct tgagcattgc
    15181 cacagatttt cttgccatca atttcaatgt cattgcgacc tgtaaaatta gccttaactc
    15241 ctaaatcagc caaggtctca ataactggct gtgagaaggt tttaaaatca aaggctcctt
    15301 ctgttgtttt attggaaata atcgtgtagt taaggttatt gagatcatgg taaactgcac
    15361 caccgccaga caagcgacga accacatgaa taccatgctg ttcgatgtac tccttgttga
    15421 tttcctgaat ggtattttga tgcttaccaa taataatagc cggctcattg atccagagga
    15481 taaacaattc atcctcatca accaattctc taaaggcata agcctctaga gcaatgttaa
    15541 aggcagggtt gtggctctta ttaacaatgt atttcatttc tatctcctat agcgataatc
    15601 gttatcatat tctattcttt attctaatgg aaactcttac aaaagacaag ctaaaagagg
    15661 ctagcaaaag caagggaact agtaaatgct tcctcaatca agaaccatct gcaagctagc
    15721 agtaaagctt gatctaactt aaagagcctt ccttgtatca acgaaagagc tgagaaatct
    15781 ttttcccagc ccttttttat cgcagctata tagctagctt attttttacg ttttggtggg
    15841 ttatgaatgg cttcgccaag cacatctgca aaggcttcgt acatcacctc tgagaaggtt
    15901 gggtgtccat gaattgacaa tagcaattca tcaactgtta gctcagcctc catgattgtg
    15961 gctgcttcat tgatcatttc agcggctgct ggaccaatga tgtgaacacc aagtatttca
    16021 tggtatttag catctgcaat aacctttaca aagccatgag cctcgtttga cgcaatagca
    16081 cgaccatttc ctgtaaagct atttttacca ataagaacat cgccatattg ctcacgagcc
    16141 tgctcttcag ttaaaccaac catagcgacc tcagggtgag tatagaccgc cgctggagtg
    16201 tattttaggt tagccttacg tgttgtgctg ccatgcatgg cattctcagc agccacctca
    16261 cccatacggt aagcagcgtg ggcaagcatt ttagtgccgt taacatcacc cggtgcataa
    16321 atgcctggga ttgacgtttc ttggtagtca ttaaccttaa tgcggttacg gtccatttca
    16381 aggttgaggt tttcaagacc attcatctgt ggcacacgtc caatagatag caaggccttt
    16441 tcagcaacaa cctcttcgcc attattaagc ttcaaggtca actggttgtt ggcttcaaca
    16501 atctcagaga caccaactga ggtctttatt gtcatgcctt tcttagaaag gattttttga
    16561 agctccagtg aaacctcctt gtccatggca ggaataatgc ggtcagccat ttcaataact
    16621 gtaacctcta caccgtaaga ggcccaaaca agaccaagct caataccaac aacaccaccg
    16681 cccataacag caagtgattt cggcatttca cgcaaatcaa gaatatcatc agatgtcaag
    16741 acaagcttag aatcaatccc tggaatattg atgcgtgaga ccttagagcc tgtcgcaaga
    16801 ataatattgc gccctttaat ggtttgcaca ccaatggtaa ccgttttatc aggatttacc
    16861 tgaccaaggc cattaaagat ggttaccttg ttggctttaa gaagcccttg aaccccacct
    16921 gttagcgtct taacaaccgt atttttaaag tcaactgtct tatccatgtc aatagtatag
    16981 ttggttgaag caaggttaat cccgcgtcct gctgcaatct tgatgccatc aaggatttca
    17041 gcatttttga ggtaggtttt tgttgggata cagccaacgt ttaagcaggt accgccaaat
    17101 tcagattttt caacgatagc aatcttgccg cccagctgag caccacgaat agcagcgtag
    17161 taacccgcag gaccgccacc gacaacaatg atgtcatatt catcagcagc aagctctgcc
    17221 tttggtgctg atggcgctga tccttgatcc ggtgcctttg gcacctcaag accagccgcc
    17281 tgtaaatcct cggttgtacg cgcaacattg acatcagccg ctgctgggct tgatacatcg
    17341 atagcttcac ccgcagctcc aatgtagccg ataacttcgg ttacagggac tgtctcacct
    17401 gcctggcgaa tgatttttaa aagcacacct gagtcttctg cttctaattc catattggtc
    17461 ttgtctgaca tgatttccag aagaatgtca ccctcgctga cagtgtcacc ctcctgcttt
    17521 ttccactcga tgatctcgcc ttcttgcatg tcaacaccga gctttggcat aataatttca
    17581 acagccataa tgatattgta aggaacgttc aaatgcaatc agatgcctta acaatcagca
    17641 ctggctaaca taagcctgct aaaagccctg catttagctc atagctagtg actacgagct
    17701 cgttccagat cctttctata gttttaaaga attatctttt cgttactttg tttctgaaat
    17761 atgctctctt tgcatcgcag gccataaggc ctgtcatcag attagcagtt caaatggatt
    17821 ttccatcaat tttttgagat caaccatgaa tttagcacca ttcatgccgt ccaccagacg
    17881 gtggtcaatt gtcagacaca ttgccatgat tggacgtgca acaatctcac catcgaccac
    17941 tgttggggtt ggaatggttg ccccaatacc tagaatagct gaattaggct gattgataat
    18001 tggattgaag gttttggtgc caaacatacc cagatttgtg atggagaagg ttgagcctga
    18061 catttcggta gcctttagct tgcctccttg agcctttttg ataacgtcct tagaagcaag
    18121 gacaaactct gagagactca tcttatctgc accatgaaca actggcacaa ctagcccatc
    18181 atcaagtcct acagcaatac caaggttgac aaagcgatga agctcaatat cattagcatc
    18241 attaatcaat gacgcattca tgtattcgtg ctctggcttc atcaaggtct taacaacggc
    18301 taaaccaatc aagtcagtaa agctaacctt tagccctgtt ttagccatga ttgggtcaat
    18361 cagcttcttg cgcaaggcaa tcatttcggt catgtcaatg tcataattaa gcgtaaaggt
    18421 tggtgctgta aggtaggaat gtgtcatacc ctttgaaata gccttacgca tagcagacat
    18481 cttcttaatt tcaacaccct ctggaagctc cttagcaggc ttttcttcag caatagatgc
    18541 tttttccaca gcaggtgctg ctgcgccaag cacagccaaa atgtcctcct tggtaatctt
    18601 gccaccaata cctgttccga ccaccgctgc aaggtcaact cccttgtcgg cagctatctt
    18661 acgagcaagt ggcgttgcct taggctgagc tcctttgaag ccttcaacgt cttctttgtg
    18721 gatacggccc tttggtcctg ttcctggcac ttggttaagc tcaattccca tttctgaagc
    18781 tgctttacga gctgctggcg ttgcgcgtac cttttctccg aaggctggag cattggcaac
    18841 tgatgctacc tgaggcgctg ttgaggctgc ttctttcggt acagttgttg tattagcttc
    18901 tgctgatgtt ggtactggaa tttcagttgt tttctcactt gaagcagtac tattatcaac
    18961 agattcacct gcagcaccaa tatagccgat aacctcagtg acagggactg tttcacctgc
    19021 ctggcgagtg atttttagaa gcacacctga atcctctgct tcaagctcca tatttgtctt
    19081 gtctgacatg atttcaagaa gaatgtcacc ctcgctaaca gtgtcaccct cctgcttttt
    19141 ccactcgatg atctcgcctt cttgcatgtc aacaccgagc tttggcataa taatttcgac
    19201 agccatatat ttcctttcat ttaatcccgc agcccatgat cttaagacca gatacagctg
    19261 ctgaaaaaag ggatactgtt ttatcagcct gatgaagaaa gcctctaagc taagacttcc
    19321 tttgccatgc taatttccct tgttgaccat ttttacaata gcagccttga ttttagcaac
    19381 atctggtaag atagcttgct caagaacacg tgcataaggt actggtacgt cctcactagc
    19441 aagacgcaca attgggtgat caaggtaatc aaaggcttca ctttcagtga ccattgctgc
    19501 aatctcaccg ataaagccac cagtcttata ggcatcatta acaagcataa gcttccctgt
    19561 cttcttaaca gaattaataa ttaattcctt atctagtggg ataagggtac gtggatcaac
    19621 aacctccaca ttaataccat cagctgcaag ctcttcggct gcctgaagga cacgctctag
    19681 catacgccca taggaaacaa tggttacatc agtcccttca cgcttgatat cccccttgcc
    19741 aagtgggata taaaaatctg gatcctgatt gacctcttct tttttaccgt acaaggcctt
    19801 aggctccatg aaaataacaa tattgttatc acgaatagct gactttaaaa gtccctttgc
    19861 ttcgttagca gttccaggtg caaccacctt gatcccagga atatgcgtca accaagcctc
    19921 aagagattgc gaatgctgag ctgcagatcc aattcctgag ccagaagcaa cacgaaaagt
    19981 tgctggcgtg atcaagccac caccaaacat gtagttgttt tttgccccat tattaacaat
    20041 tgcatcaagt gcaatggtaa taaagtccat aaaagtaagg tcaacaatcg gacgaagccc
    20101 tgtaattgct gaaccaatcg ctgcacctgc aatagcagcc tctgaaatcg gcgtatcctt
    20161 gacacgtttg gcaccaaatt cctcaatcat gccaacagaa gtaccaaagt ctcctccgta
    20221 aacacctacg tcctcaccca taaggtaaat cgtgtcatct ttgcgcatct cctctgtcat
    20281 ggcaagattg atagcctcac gcaaagccat taattttgtt tctgtcatta ttatctccta
    20341 atgtttacaa aatagaattg tcaatgttac tgtgaataga tttttgctcg atgtgctagc
    20401 agatcagcta gtctacccaa acgtcctcaa aggctacaga aatgtctgga tctggactat
    20461 tttgtgcaaa ctcataagcg tcatcaattt cttgcttgac ctgtgcttga agcgcatcta
    20521 attcttcatc tgtagcaatg ccttcacctg ttaggtaagc gcgatactta agcattgggt
    20581 ccttttcctt ccactcatca acctcttctt tggtgcggta tttgccggca tcagcagttg
    20641 aatgaccaaa ccaacggtaa gactcaacct caacaacagc aggaccattg ccaccgcgaa
    20701 catgctcaac agccttactc atggtttcat aaactgccat cacatcgttg ccgtcctcac
    20761 aataaaagcc tggaatacca taagcctcag cacgcgtgta gaggtgaggt gtatttgtgg
    20821 cattgttaat gctcatggaa atcccatagc ggttgttaat gataaagaaa atcacaggaa
    20881 gcttccaagt tgctgccata ttgacagact catggaagga gccctcattt gttgcgccat
    20941 ctccagaaaa ggccacaacg atattgttgg tccccttgta ttgctgtgtc aaggcagcac
    21001 ctaccgcaag ggcatagcca cctccaacga taccatttgt tccatagttt cctttttcaa
    21061 aatcagccaa gtgcattgag ccgccgcgtc cctttgacac acctgttacc ttaccggcta
    21121 gctcagccat cattttattg aggtccatat ctttagcaat agattgccca tgcccgcggt
    21181 ggtttgaaaa aataatatca tcataggtca aatgtgccac agcgccaacg tttgctgcct
    21241 cctcaccaac tgagaagtgt gtcatgccct gcacaaatcc acgacggaca agcttattaa
    21301 tacgtgaatc aaattcacga atacgctcca ttttaaggaa catatctaaa tgttgttctt
    21361 tagaaactgt taccatttcg gcctccatat tatcatatta cttcctaatc ataaaacttt
    21421 tcttcacaat ttgcaaggat tttaatcgct ttctttgtga ctataaaagc ttttttaaga
    21481 cgttttagtt tgtggtttca caagctagat tgttatagca tctgttacat ttatatataa
    21541 cagattgaaa aatgagtcag tgtttattca gggaggtcaa gcacctattg actttgatag
    21601 tcagaaatat catcactctt taagaggaaa ataggctcta aatgacctgt ttcttctagc
    21661 acaatcatga tcacctacca aacgaacgct ttgcttgcct cgctccgata gaggcgaaat
    21721 gaactaaaaa tcgcataact aaaaatgcct gattttacct gaaaatcaga catttaaaag
    21781 ctttaagaca ttagactcag gctctaatta taatcctcta agaaaagcct gctaccttgc
    21841 actacccaag aatagcaagg caatttcatt atctcaccag gctactccag ctgtcctgca
    21901 atgtcctccc actccagcag caaggtctcc tgtttctgat taagctgatc caactctttt
    21961 tgccagtcta tcagttgagt cgtatcattt gatactagca tttgagcttc tatagcctta
    22021 gcctgtgctt ctagcccttc taaggtctgc tcaatctcct caaagcgcct tgttaagcga
    22081 cggtattcct tttggctggc cttttgaagc tgataatcag ttacagcagc ttctgctaca
    22141 tcagtctcta ctacgtgatc tgcagcagct agacgggcta attcctcccg ctctgccttt
    22201 ttttctacat aatagtcgta gtcccccaga tagagtgttg agcctgcttc agttatttct
    22261 aaaaccttag tggccactcg gttgataaaa tacctgtcat gactaacaaa caacaaggtc
    22321 ccatcaaagt caatcaaggc attttctaga acctctttgc tatcaatatc caggtggttg
    22381 gttggctcat ctagaatcag aaaattgtcc tttttcatag ataattttgt taagagcagc
    22441 cgagcctttt cgcccccaga tagcatggcc acagactttt tgacgtcctc accagaaaag
    22501 agaaaggcac ctaagcggct gcggatctca agctcagctg tcgttgggaa atcacgccaa
    22561 agctcctcca atacagaatt actaccagtc agatgagatt gcgtttggtc ataatagcct
    22621 gtttcaacat tagtcccata atggcatgtc cctttaatca aaggaatctc tccaataatg
    22681 gatttgagta gggttgactt gccaatacca tttggcccaa caatagcgat tgcatctaac
    22741 ctacggacat ctagatgaat tggctcagct aaaatatggt cattgtagcc aatagcggcg
    22801 tctgtcacct gcaaaacaac atttcctgag ggcttatcaa tctgaaaagt catactagct
    22861 gatttgcgag agctacttgg cttgtctaag cgttctagct tttctagctg cttgcgtctt
    22921 gcctgagcac gcttggtcgt tgacgctcga acaatgtttt tttggacaaa atcctctagc
    22981 ttagcaatct ctttttgctg cttgtcataa tgcttctctt ctgctgcaag cttttcagcc
    23041 tttaaatcaa taaagcgtga gtaattacca acatagcggt ctaagctatt tttagtcaga
    23101 tcaagtgtga tggttgcgac cttatccaag aaatagcggt catgactgac aatgatcaag
    23161 gctccctgat aatttaccag ataatgctcc agccaggcaa tggtttcaat atctaaatgg
    23221 ttggtcggct catcaagcac caatagctct ggcttttcta gtagcatttt tgccagggcc
    23281 aaacgggtat tttgcccacc agaaagctct gagattttca tttcccacat gctttcgtca
    23341 aacttaaagc catttaaaat agctcgaata tctgactcat aggtgaagcc atttcgcaag
    23401 cgaaagcttt ctgacagccg gtcatagtct gacatgagct ggtccagagc ttgccctgat
    23461 cgactggcca tatcagcctc catttgcctt agtcgctgct catcaaccct caattcagca
    23521 aataccttta gcatttcctg ataaatggtc ttgtcagact caaatcggct attttgtgcc
    23581 aaataagata gggttaagtc cctttttcga ctaacctcac cgctagttgg ctcttcttct
    23641 ccaactaaaa tcttaagaag ggttgatttg ccagcaccat ttggcccaac caaggcaatg
    23701 cgatcacgtt caccaacctg cagcgatagg ttttgaaaaa gcacctctcc tgaaaaagag
    23761 cgctcaatgt tatttccttg taatataatc atacccttat tgtagcaaaa aaatgccctt
    23821 ttggggggca cttttagtta tttttacagg taagataaga ctcatcaaca agctaaagac
    23881 ataagcctta ggctaacatc gcttatcacc cttagtggta tttatctgat gagacaaact
    23941 gctgcttgaa aaaccagtgg gttgacctgt tagcgtatcc aacaatcgca ccacctgctc
    24001 agttatgctt gaaatgctat tagccagtga ggaatcacta tggttcgaat aataaatcaa
    24061 accaaaaata agcaatacca atactattag ggtctgcaaa cagcctctga caagctgcca
    24121 gacaagcttc agcagaagct ttgggaggca taagaggata gtcagtagtt ttttcatcgt
    24181 aataagccta aattctttcg tttaggatag cctttcttcc ttgtggtaag caatcggcag
    24241 ccaatctaat agggcctcta gctgctgatt ccaataatac cattcgtgcc tgccatgatc
    24301 cttacgataa tcaatagtca agccaagcct tctcaactca gcaactgcct tttcattggc
    24361 ttcaaacaaa aagtcctcat agccacacca agcgtatagc tgggtttgac catcactttc
    24421 tgctgctata cttgtcaaat aatgcttttt gatatcagga gcattcaaat ctccaaaaac
    24481 accctgccaa taaggcagct cacctatacc ttgctgtaat agcatttccg gcgaaaaatg
    24541 caaggcccca gaaaaggaag cagcatagga aaagcgattg ctttttaagg cccatttaaa
    24601 ggcaccatag cctcccattg acagcccagc aacaaaggtt ttttcacgct tagtggtcat
    24661 attaggaaag aaagaagcta atagccgagg aagttcctct gcaatagctt ggtaataatt
    24721 cataccgtag gtggtatcgg tataccagcc taaatcagtc gatggcatca ccacgattaa
    24781 attggtatgg cgaagcagcc tttcaatatt agtccgcttt tgccaggaat tttcatttcc
    24841 tcccatacca tgtaacagat aaagaactgg aatatcttgg tagccttgct cttctgggct
    24901 aagctcagac tgatcagggt agatcacctt gacatgtctt tccatagcca agatctctga
    24961 atgatactca atgctaatgc ttgccatcag ctcacctcct ttttaatatc accaaagcat
    25021 aaggaaagcc cactcttaag acctaaaagc cagatcctat ttgaccagct tttaggcagg
    25081 gctgtatctg tattaacgga cctccataac aaccggaaga atagctggcc gacgcttggt
    25141 ctgctcaaat aaaaaccttg agagctcctc tctaacagag cctttcaatt cactccaatc
    25201 aaaatgatcc ccttgcagat aattgccaac tgttgtgttg accaattcag cactttctcg
    25261 taaaatatct ctgctctttt tcacatagac aaatccgcga gtgttgacct tagccttaga
    25321 gataatacgt ttttcctttt tagatactgt gatcgcaaca ataaaaatac cgtcctctga
    25381 taagacctta cggtctctca aaacaatatt gccaacatca ccaatggcat ttccatcaat
    25441 catcacatca ctagcaggaa ccgcaccctc gtgtaagaag ccatcctcat caagcaccat
    25501 gatgtcacca cgcttcataa tatgaatatt ttcaggtagt ataccagcct cctcagctaa
    25561 atgagcatga gcagctagat cgcggtattc accttgaatc gggaacaggt attttggttt
    25621 gacgagatta atcatcagct gcaggtcacg cgcattggca tgtccagaaa cacgtaaatg
    25681 ctgcgtgatg agcttaacag agccacctgc tttatagata aggttttcaa cacgagcaac
    25741 cattgcttcc ttggcagcgc ttggcgttgt gacaatgtaa accagatctc cgtccttgat
    25801 ttgcacgtgg cgatgacgcc ctattgccat tttctgtagg ctattaatcg gctcacccat
    25861 acgtccagcc tccagaacaa tcaattcgtg atcctcaaac ttagacatat cctttggctt
    25921 gattaatagc ttttcatcag caatcactag ctttttaaga cgaagtgctg ttctgacaat
    25981 attttcagcg tcagtacctg tcagtaccac tcgcctgcta taggctgctg cagaatcaaa
    26041 gacctgctgg atacgaacaa gatttgaagc gacagctgca atgataatcc gcccgtcggc
    26101 atgagcaatc accttatcca tctcctcgcc aacctcagct tcgctggcag tctgctcatt
    26161 gcttgtggca ttggccgagt cagctaatag ggctaacacc ccttcttttc caatgtctgc
    26221 caagcgagct aggtctgtct gatagccctc acgcgaagcc tggtcaaact tgaaatcacc
    26281 tgtatagaca atattcccct tatcggttcc aataaccacg cctaaacttt caggaataga
    26341 atgtgttgtc ttaaagaagg aaaccaagcc atctttaaat tcaatttctg tgtcactgtc
    26401 gaccacatgg aaattcttaa atctcttggt gctattattg gccttgacaa acaattttgc
    26461 tagctcgatg gtcaattctg aaccaaatac tggcactgga acctccgcca acaggtaagg
    26521 caaagctccg atagcatcag catgcccatg acttaaaaag actccctgaa ccttgtcctt
    26581 gttttcaatt acataatcaa gacttggaat taccaaatct acacctagct gttctgtttc
    26641 agggtatttc aagccagcat ccaaaatgaa catggaatcg ttaatctcta ctagatagaa
    26701 gtttttcccg tactcacgta cgcctcctaa tgcaataatg tttatatcag tcatgatact
    26761 ccttttttta tattagttat tacaaacggt ccttactggg taagtcgaat tactgtcttg
    26821 cagctaagct gcactctttt acagtatatc atattttagg gcttattacc tcaaattgcc
    26881 ttgagacttt ctcaatcttt tcaatagatt atcaaaaaag ccaagggaag gctttcattc
    26941 caatggcttt tagagtattt attttagtca aaaagctggt aataatcagc aatggtcatt
    27001 tgagattttc tcttctgatc aaggtcttga atgattttac catttttcat cacaatcagg
    27061 cgattaccat agttaagagc gtcctccatg tgatgcgtta tcattaaggc tgtcaagcga
    27121 tccttagcta caaaatcatc agtcaaggcc attaaggctt ggctggtctt agggtctagc
    27181 gctgcagtat gctcatctaa tagtaaaagc tctggtcttt ttagggttgc catgagtaag
    27241 ctaagggcct gtctttgacc gcctgataag agaccagtcg gagtctccag atgattttcc
    27301 aagccatttc caactcgctt gaccaagtca gcaaagtctg ccatataatg gctaatcctg
    27361 cgtgatgaca agcctcgcct ttcccctctt tgccttgcaa tcaaaaggtt ttcagctact
    27421 gtcattcgag gtgctgttcc cattttagga tcctgaaaaa cacgtgatag gtagctagct
    27481 cttttttctg ctggcaggtg cgtcacatca tgccctaaaa gcttaatttg acccttgctt
    27541 aacaatagcg tcccagcaat cacattaaaa agggttgatt taccagcgcc attcccacca
    27601 agaatcgtta aaaaatcatg ctcataaatg gtcaaggaaa catcatctaa aatagcctta
    27661 gtctcatcaa agccattatt gacttcgaca gtagcgtgaa ttaattcaat aatttttctc
    27721 atcgtgataa gctagcctcc ttaataattg ctttttttag cacaggcacc atcaggcaaa
    27781 gtgctaatat aatggcacta aatagcttaa gataatttgt attaaagcca agagcaataa
    27841 ctactgagat taaaaattga tacaggatag aaccaaccac aatggctatc aagcgctcaa
    27901 gcagggttag gcctgtagaa tataaaacct caccaacaat aatactcgca aggccaatta
    27961 caatcacacc aatccccttt gaaacatcag catagccatc ttgctgacta accaaggcac
    28021 cagataaggc tatcaaggca ttagagatcg ctaagcccat aagctccata cgatcagtat
    28081 gaatcccaaa gctcttagcc atatcccgat tatctcctgt ggcaatataa gcctgaccaa
    28141 tattggtgta aagaaaatac attaacaaaa aaatcaccaa tgtagctaca accaaaccag
    28201 ctaccaacac attggtgtca gctgcaaagg gaaggtagtc ctgaatgcgc ttgatatcat
    28261 gcaagcccaa attggccctg cccataacca taagcataat ggaatggcag gaggtcatga
    28321 ctagtatgcc ggcaagaagt gttggtatct ttccttttgt gtataacagg cctgtggcga
    28381 agcctgccaa ggcacccgcc agcatagcag ccagagtagc caggatagga tttaaaccga
    28441 gattgagcag agttactgct acagcacctc ctaaaggaaa ggacccttct gttgtcatat
    28501 ctgggaaatt caatattcta aaggtcaggt aaatccccaa gccaagaatt ccccataaca
    28561 agccttgtga tacagatgaa ataatcatat gaactccttt tctattgctt acctgtaagg
    28621 tcagaacgct tcagcaggtc ttttgagatc ataagaccta aatcccttgc tgcctttaga
    28681 tttaaaaatg gcttaccgtc atcaactacc tcgacaggaa cctctgatac ctcttttcca
    28741 gccataagct gcagcacctg cctagctgtc tcaaccccta attggtattg actttgtgaa
    28801 atagaagcaa gactcccttg ctcaaccatt gtatcaacac ttgagtagac cggaagctgt
    28861 gctgcatttg aggcaacaat caccgctgaa aaagcactgg caatagtatt atcctgtggg
    28921 ataaaaacag catctacctt ctcagtcatc acagacatgg tcgtggtaac ctcatttgtt
    28981 gaggggacag cgtaagctag aacctccaag ccttgctttt ctgcaagagc tgtaaagtcc
    29041 ttgacctgtg atattgaatt gtcctcactg cttgcataaa ggacaccgac ccttttgacc
    29101 tgaggggtca tctccttgat cagatcaacc gtctgtcgaa caggaacctt atttgataag
    29161 ccagtaacat ttgcctcagg cctgtctaag tgcttgacta atttagcacc aactggatca
    29221 gaaatagctg acatcacaac cgggatagtc ttggttgctg ctgctaatcc ttgagctgca
    29281 ggcgttgcga tgccaacaac aatatcgttt gttttgacca gctgcttgct catggtctga
    29341 atcttacttt gatctccttc tgcattcata agggtaatgc tgaccttttg ctctggctga
    29401 tgatgcttct ttagctcgtc tttaatgccc tgtgcaatct ggtcaagcgc ctcatgagta
    29461 accagctgca atataccaac cttaaccaca cgcttgctgg ctaactgtgg ctgttttttg
    29521 ccctctttta gcactagcga agcagcaacc attaaaaaga gtgcaatgac tgttacgata
    29581 agacctttat gtttcatgtt ctacctctta atttccattc ttactccgtt gctaacattt
    29641 agagtactca caaaaagaaa aaacgcttag taatcagcta ctaggcgctt tttttgaaat
    29701 ccaatgtcag cgcatagata cctttttaga agtactctaa aagtcgtatc tatgctaacc
    29761 cataaacaca actttatcta tgccagcttt gccaatttat catatgctgt gtttgcttca
    29821 tcttggattt cctttcttgt ttttttacat tataacctaa aagctcaaaa atacaagagc
    29881 atttgaacat atttttccat tattttttgt ggtataatga aagaattaga actcaggagg
    29941 gagaaaccat gtcatttgac ggctttttct tacatcattt aactcaagag ctcaaccata
    30001 gtattgttaa tgggcgcatt caaaaagtca atcaaccctt tgataatgag ttggttctga
    30061 ctatccgtaa ccatcgccaa acttacaagc tcttgctctc agctcatccg gtttttggac
    30121 gcattcaact gacccaaaca gactttcaaa atcctcaatt tcccaatacc tttaccatga
    30181 tcatgcgcaa ataccttcaa ggagctatca ttgaaggctt tgagcagatt gataatgacc
    30241 gcatcatcga aatgaccgtc tctaacaaaa atgagattgg cgatgccata aagacgacat
    30301 tgatcatcga aattatgggc aagcacagca atattattct ggttgaccgt catgaaaaca
    30361 aaattatcga gtctatcaag cacgtcggct tttcccaaaa ttcctaccgg actattttac
    30421 caggatcagc ctatatcgag cctccgaaaa caactgctgt caatcctttt acgatctcag
    30481 atatcgcttt atttgaagtc ctgcaaacac aggagttatc tgctaaaaat cttcaaaagc
    30541 atttccaagg gcttggccga gataccgcac aagagctatc cagtctcctg acaactgata
    30601 agctaaaacg gtttagagac ttttttcaaa gacctagtca gccaagtcta actcagacct
    30661 cctttgctcc agttgccttc tcaaacacac tgaagacctt ccagaatcta tctcagctgc
    30721 tagattatta ttatcatgac aaggctgaga gagatcgtat caaccagcag gccagtgacc
    30781 tgatccaccg cgttcaaaac gaattggaaa aaaatcgcag caaactgatt aagcaagagg
    30841 ctgagctgct agccactgaa aatgcggagg actttcgcca aaagggtgag ctcttaacaa
    30901 cctatctgag cctggtgcca aatgaccagg attcagttga gcttgataac tactataccg
    30961 gccaaaaaat aaccattgca cttgataagg cgttgactcc caatcaaaat gcccaacgct
    31021 attttaaaaa atatcaaaaa ttaaaagaag ctgtcaagca cctctcaggt ctcatcgctg
    31081 acacgcaaca aaccatcgct tattttgaaa gcgttgatta caatctatct caggcaacga
    31141 ttgatgaaat tgaggacatt cgagaagagc ttattcaggc tggctttgtg aaaagccgta
    31201 agcataacaa gcaccacaaa cgtaaaaagc cagagcaata cctggcttca gatggcaaaa
    31261 caattattat ggtcggacgt aacaatctgc aaaatgagga attaaccttt aaaatggcca
    31321 aaaaaggcga gctctggttt catgctaagg atattcccgg cagccatgtg atcattaagg
    31381 acaatctaag cccaagcgac gaggtcaaaa ctgatgctgc tgaattggcg gcctattatt
    31441 ctaaagcaag actttccaat ctcgttcagg tggacatgat tgaagccaaa aagctgcaca
    31501 agccaagtgg tgcaaagcct ggctttgtca cctatacagg acaaaagaca ctaagagtga
    31561 cacctataga aagcaagatt caagccatga agtgctcccc ttcagcctct tcctcatagg
    31621 actacagcaa taaagataaa aaaagctaca gcctcacact tggagatagg tccagtctta
    31681 aagctgcggc ttttttatca ttacttgtta atcatctctc aaatcatcta agaagccttg
    31741 catatgaata tcatctggaa cctgctgcaa ataccttttt gcctgcttaa ctgcttgatc
    31801 agtatagccg aattccctta ataaataagc ataatcctgt aaaaagtcag gattttcttt
    31861 taggtctcct tcgatatctt tatagatagt gagggctttt tcttgctgct ccagagcctg
    31921 ataggccttg gcaagattcc atttagttag cacatgatca atctcctcat gctcaagagc
    31981 aatgacctcc tcaaaacgct ccatatccaa gtacaggcta gataagcgca tgatgacctc
    32041 ttcgtcatca acagctactt ccttggccct gagcaaatac cgctctgagc cagctggatc
    32101 atgcaattca aaggcaagct gtgaagcaag caacagcagc tgggggtcaa aggcattttt
    32161 acgcagaccc tgctgaacta ggcgtaaggc ctcttctgtc cgatgctcct cacgcaagct
    32221 catggcatag gggtactcgt agcctaaaaa gtctgcattc atcgtttcta attgcttgaa
    32281 atagagattg gccttttggt aagcagcctg atcatataaa atcgtcgcca gctcaaacac
    32341 tgtctcatcg tcatactcaa tggcaagagc cttttcaaga aactctacag cagcttcaaa
    32401 tttccctaaa taagcatagg cacgccctat gcgctggtag gttgagatac ctgtcagctc
    32461 aagaatgtga cgattatcaa gcctagcata ttgctcaata gcctcgctaa agtgctccag
    32521 agacatctcg atttcggcta agccaaagat cactatcggc tcctgactca attcagctgc
    32581 ttgaagtagc ttctcacgcg ccacatcagt tagcccctcc aaatcataaa gatcagccat
    32641 gacgagcaga gcagacaaat aatcagcact atcctctgga atcctatcaa ggtacataaa
    32701 ggcctcttca atgacattat cctcagctgc aatctgagca agattaatat tgacctccgg
    32761 ataagcctca cagacctgca aataaatcgt cttagcatgc agtaaaaaac caatactctc
    32821 taggtattct gccaaagcca acaaggtctc agcatcgtcc tcctgcaagg ctctttgaaa
    32881 atagctttct gcctgctcta aatcctgttg ctctagtgag gcaatcattt tttcactatt
    32941 taacatcttc agcgaccctc tcagcttctg taggctcttc ctcatacagg cctgtaatat
    33001 ccttgtacca atcaaatagc tccttcacaa caaccttaac agaagcataa actggaatga
    33061 caagaaagac accccagacc ccaaacattg accctgctgt caataataaa aacataatgg
    33121 taatcgggtg aatgctcagc ttatttccaa gcactagcgg cgcgacaaaa cgtccttcaa
    33181 tcgtttgttc aataacaaaa ataatcaaca ccttgatcag catcaagggt ccttgcacca
    33241 ttcccataat cactacagga atcatggcta aaaagctccc cagataagga atcatattaa
    33301 gaaagcctgc aataatacca aaggtaatag aatagttcaa accaacaagg ctaaacatca
    33361 ctgaaaacat gagaccaacc acaatcgcaa cggtcacctg tccctgcaca tagccagata
    33421 attgcttgtt gatttctcct aagacacgtg ccataggctg gcgcagctta atcggaagca
    33481 cattgaccaa accatttttc atatggccac tgtcacgcag aaaataaaag agaataaaag
    33541 gtgacatgat gattgcaaca gtaatacggg caatagctcc agcaaaattt cctgcccaat
    33601 caatagcatt tttagagaag ctttgcgcat aatctagagc cttttggctc atactagtca
    33661 gcatatcctg caggttggac ctgtagctaa ccagccattc gttttcaagt agcttattag
    33721 cctctagatt gaccttggca acatatttgg gaaggtcttc gacaaagctc cttagctggt
    33781 cttgaatcat agggataaag ccagaaatag cccagaaaaa taggagaatt actaagccaa
    33841 agacaataaa aatagaggct gtgcgatttg gacctagctt ctcaaccata tcaactaatg
    33901 gcttggtcaa ataatacagg atagttgaga taaccagcgg cagcatgata atggccaaaa
    33961 atgacaagat cggtgtaaag aggaaggata tttttgtaaa gacaaaaata gtcagaaaaa
    34021 ccagcagcgt gattaacaaa accatcaccg cctgattatt taaaaaccat ttgtaaaata
    34081 gactatcatg atgattaggc ttagaatgca atgacattaa tggtatcgtc ctttcttaat
    34141 tgtggcatca ttctgatgag agcttttagg ttagttgact taataaaagg tgactgtttt
    34201 ttccactagc ttgttgtggt catcatacct aaatttagca gaaaaaaacg gccggtcttc
    34261 cagtatccac ttgaaaatgt cgtaatctcc ctcccaggtt ggcttttcca gcacctgatc
    34321 atagggaacc cattctaggg tcccttctct ggactcctca tcagcaatta agtcaccttc
    34381 aaagtctgtc accttaaaca cgtaagtata ccaatcatgc cctggtgtaa aatcaggaaa
    34441 ggtaatcact cccttaaagt ccattgcttt taccagcagg tgagtttcct ctaaaatttc
    34501 acgtctggca cagtcatcag gagattcgcc tggctctaat ttgccaccaa ctgaaatcca
    34561 cttaccttgg tgaacatcat tttccttctt gttgcgatgc agcagcaata aagcctcacc
    34621 gttatcaata taacaaatcg ttgctaactt agtcattcat acccttcctt tgtttagttg
    34681 ttactattat accaatctct gagaaatatg ccatcatttt atcatttaag cacatcaaac
    34741 aagaaaacca caatcactac aactcttagc cctgtactag caaaaaagcc ttgataaggc
    34801 aacgtctgct gactcatcaa gacttatcac tatttaacga atcacttcct gtgtcttagc
    34861 gtaattggct tcaactgctt ctttttcgga acgccaccaa tcctgatgat cagtatacca
    34921 ttggatcgtt tgctcaagtc cttctgaaaa atcagtaaac tgtggctccc agccaagctc
    34981 ctgacgaagc tttgtcgaat caatagcata gcgtaaatcg tggcctgcac gatccgttac
    35041 atggtcataa gcgtccttag gctgccccat tttatccagg attaattcca gcacttcctt
    35101 attatttttt tcgccgtcag ctccaataag gtaggtctca ccaatacgtc ccttggtcaa
    35161 aatggcccaa acaccagttg agtggtcatt ggtgtgaatc cagtcacgaa cattctttcc
    35221 ttcaccatac aattttggct tgataccaga caagatatta gtgatctgac gagggataaa
    35281 tttctcgata tgctggtagg gaccataatt atttgaacag tttgaaatgg ttgccttcac
    35341 gccaaaggag cgaacccagg ccttaacaat caaatcagag gctgccttgg ttgatgaata
    35401 aggtgacgac ggattatagt tagtatcagc ggtgaatttt tcacctggcc cctcaccatg
    35461 acctggcaaa tcctcacgca gtggcagatc cccataaacc tcatcagtgg acacatgatg
    35521 gaagcgaata tcatatttac gagccgcctc taagagtgta taagtcccaa cgaagttcgt
    35581 gtaaataaat ggacttgggt cattgagtga attatcattg tggctttcag cagcatagtg
    35641 gacaatagca tctgccttag cggccagctt atctaccaat tcagcatcag caatgtcacc
    35701 aacaaccaac tccacgcgat cacccaaaat ctcctcaagg ttggcacgat tgccagcgta
    35761 ggtgagctta tccaaaacag ttacgtgaac ctctgggtga tggttgtaaa cataatgtac
    35821 gaagtttgaa ccgataaagc cagcgccacc ggtaacaata atgtttttat attcagacat
    35881 gttttttctt ttcctttgtt ttcagctatc agcactcaaa atgcagctta atccgacagg
    35941 caagctcagt taccagtgaa aacagcgact aagctgcctc acctcattgc tcctaccatc
    36001 cataaggtcc ttcctatcag aaggatacag agacactccc atcaaaagcc atagcttatt
    36061 tcaaatgcta attatgataa atcttcttgt ctcaaaggct taacggcctc taggaaggga
    36121 tggcttttat ctgcttctga aacctctgct tgttcaagac tttcccacgc aatcccaagg
    36181 cttgggtcag cataattaac aaaggcatat ttttgcttga gctcaagcgc ccaataatca
    36241 ttgaccagat aggtataagc caccttatca gtcagtactt gaaagccatt agcaacacct
    36301 cgagggacaa aaatcccctt tgaagcgtca atgactgttt gataggtatg cccaaagcta
    36361 tcaccctcac gaagatcaac ccaagctcca agaaccttac cctcatcagc aacagagatg
    36421 tacttgtccc aaggctctgc atgcaggcct cgaagcacat gcttgcgcga aaatgaaata
    36481 ttgttttgca gcttacctgc ggcaaaaaac tgctcaggaa agcctagagg aatcattttt
    36541 tccttttgaa aattttcctt aaaccagcca cgattgtccc ctcgaacagg gatatcaaac
    36601 tccaaaagtc caggaatggc ttcaatttcc cgacaggcta aggctttatc aaaaaattgt
    36661 tctgtcatca agcttctcca atcaaccgca gcaggtactg cccgtattcg tttttcttaa
    36721 gcgactgcgc tagctggtag acatcttctt tagtgatata acccatgcga taggcaatct
    36781 cctctaggtt ggccacctga gcgttttgca agcgttgaac tgtctcgatg tattgggcag
    36841 cctccagcag gctttcatga gtgccagtat ctagccaggc aaagccacgt cccatcaact
    36901 caaccgatag gtcgccacgc tctaaatagg ctttattaac atcagtaatc tcaagctctc
    36961 ctctggcact tggtttaatg cttttagcaa tctcgactac atcattgtcg taaaaataaa
    37021 ggcctgttac agcaaaatgt gacttaggaa ctgccggctt ttcttcgata gaaatggcat
    37081 tcatctcatc gtcaaactcc acaaccccaa aacgctccgg atccttgacc tgataaccaa
    37141 aaacagtggc tcctttttcc ttagctgctg ccttttggag cattttcgta aggccgtttc
    37201 catgatagat gttgtcacct aaaatcaagg caactcgatc atcaccaata aactcctcac
    37261 caatgataaa ggcctgtgct aagccgtcag gacttggttg ctccttgtag gacaagctta
    37321 tcccaaactc tgagccatcg cctaatagct cttcaaatct tggaagatct tggggagttg
    37381 aaataatcaa aatgtctcga atccctgcca gcatcagtgt tgataaggga taataaatca
    37441 ttggcttatc ataaattggc atcaattgct ttgaagctgc acgagtaaga gggtacaagc
    37501 gtgttcctga tcctcctgcc agaataatac ctttcatcgt agctctcctc attttataat
    37561 acgtcactat tttatcattt tttaaaaaca gtgtcacttt ttatcattaa tccgacgaat
    37621 ataatgatga atcgggtatt gactagtatc taagctagct ttttgcccca aaagcagggc
    37681 aatcagctgc tgagcaatca aaggacctag ggtcaagcca gatgagccta gaccgcttgc
    37741 ggcgtaaaca cctggtagct gaggtacctg cccaaaaaat ggagaaaaat ctctggtata
    37801 ggctcgaatg cctacgcggt aagaaacatc agaggcagaa ctcagcttag ggtaataggt
    37861 caaggcctcc tgctccaagg cctctaaaac agctacatca ggctcaaggt catagccctt
    37921 atcattttca tgactcgctc ctacagacaa cctatcatgc tcaaagggaa taatatccag
    37981 ctccccctct ggcatgacca ctgcgtagtt atctgtagtc acattcgcaa tgtgataatc
    38041 aatgagctgt cctttttgcg gtcgaatatc cacctgatag ccaagtggct caagcaattc
    38101 tggcagccaa gcaccagcgg ctagaatcag ccgatcaaag accataccat caacgagata
    38161 gccttgcttt tctatgctta tgccaacacg ctttttaacc acctgatagc cactagcttc
    38221 aagcaaacac tgacataggt ctgccccatc aacacgtgca gccccagaag cccataccag
    38281 ctgctcaaaa ccctgtaaat caggaaaatc aaccctaatg tccgaacgac accttatcgc
    38341 caaatctcca atcaaaggcg actcttgctt gcgtctaatg gccagctggt agagctcctc
    38401 tagcttgtcc tcattctttt ttaataaata aacaccagtc tgcttataaa aatgtgtaga
    38461 aagcccctct ttttgcagct ccttgattaa gtcctgataa caatctgctc ctaaccgagc
    38521 cagctggtac caagccttat tccttctttt tgaaaaccaa gggcagataa tgccagcggc
    38581 tgccttagtt gcttgaccat taccatcatc aaaaatagta acctgctgat acccttgttt
    38641 ttttaaataa taagcggcgc ttgaacctac aattccagct ccaatgattg ctatcgttgt
    38701 cattgccgtt tccattctat catactgctt accaagcata ggccatactc agtcatgcta
    38761 tagatgacta aagggatttg ttgacgcctt gctagccata atggttactt gccagccttc
    38821 ctcttttttc caagcctgca tcttggcaag tagtttatca ataaataagg actcgatgtg
    38881 atgccctgga tcaattgcca gcaggccttc tgtcagcatt tcctgtgctg tgtgataata
    38941 aatgtcacca gtaatataaa cttgagctcc cttagcaagc gctgcctgat aaaatttatc
    39001 accactgccc ccacaaatag ccactcgcga aatcaaaggg ttttgaccag tatatcgaac
    39061 cagccgaacc acatcaagcc caaaggcttc tttaactgta agtcctaact cctccaagct
    39121 ttgctctgct acatttccga cacgtccaat accataccca tcttgcgtct caaccaatac
    39181 ctctgtctgc tcaatgccca acagctcaca aaaccaatcg ttgagcccgt cagagacaat
    39241 atctatattg gtatgactga catagacaga aatatcgtgc ttcaccagct caaggacaat
    39301 atctcgctgt ggcgaggaga ccaagtcctt caagccctta aaaataggag cgtgcttggt
    39361 gataatcagg tctaccttgg ccgcaatagc ttcggcaacg gtattttctc tcacatcaag
    39421 ggtgatcatt acccttttga cctccttatc cagagagcca atttggaggc cacacacatc
    39481 tcctgacatg gatagctcaa gcggacaata gctttcatat ttttcgatga ttgttctagc
    39541 tttcatgact gatgacctcc tcaatcgctt ttattttttg agaaatgcta gcgcgttcaa
    39601 caggcttcgt tgctggcaca caagacaggg catagacaag cttatctcgc tctttttgcc
    39661 atttagccac aaagactgat gacctttcct gagacaagaa aggaccaaag cgctgctcct
    39721 gatctgttag actttgttga ccaggctctg caacaatgat ttcataatat ttgccatttt
    39781 ctgtcatgat ggtttcagca ctaatacaaa aagcattggc agatagccaa gcacgcagct
    39841 catcctctcg attattgggc tgtaaaatca agcgctcaat cccttgcagc ttttccttac
    39901 cagccgctaa aatgtcagct attaaacgcc ctcccatgcc acagatggtt atgcagtcta
    39961 cagcatctct cgcctcaaag gcagctaagc cattagccag acgcacctca atatgctctg
    40021 tcaaaccata ttgtgacaca ttttttaggg ctgatacaaa aggtcccttg accacctcac
    40081 ctgcaatcgc ctcttgaata tgctcggttt caaccaaaaa aataggaaga taagcatgat
    40141 cacttcccac gtctaaaagc ttagcaccat cagggacata ggatgccaca tggcgtaagc
    40201 gctttgataa atgactttcc attttcttaa tccttctaac aactaatcgt atcactatta
    40261 tagcaaaata cagaccaatt aaaaagaaag ccacatcaga ccttcttttt accataggta
    40321 gtcttgtaat agctgcaata gctctgtact gggcaggtat cacacttagg atgcttagcc
    40381 aagcagtgat agcgtccaaa aaagatcaaa cggtggtggg tgatgatcca atccttctta
    40441 ggaagcttgg ccatcaaatc agcttcaatt tcagtaacat cggcatctgg ggcagaaatg
    40501 ttcaagcgct tggcaatcct tgacacatgc gtgtcaactg cgattgcagg gacaccataa
    40561 atctctgcca agaccacatt agcagtctta cggcctactc ctggtaagga ttcgagctcc
    40621 ttatgggttt ttggtacctg accatcaaac tgtgtcagta gctgctgagc tgtcttgatg
    40681 atattttttg ccttattttt atacaagcca attgtcctta ggtgatcctc aacatctgac
    40741 acatttgcct gagccaaatc tgaaagctct gggtagcttt gccacagctt aggggtaacc
    40801 ttgttgactg ccttatcagt tgtctgcgct gataggataa ccgtaataag aagctgaaag
    40861 ggcttttctt ggtcccaatt cagctcgccc ttagcctctg gaaacatctc accaatgatt
    40921 gatagaacct tttttaatcg ttctcttcct atcctcatta gttactccaa aggttcatcg
    40981 ccgcaagaaa atcatctgaa accgtcactt cagacgccgt catatcctct ctggcacgct
    41041 ttttttcctc aagctgcctg aggcttgtaa ttccctcctt gcgccaattt cttagaatag
    41101 cctgaatata tttccaattg gtttttccat taaagacagc ctctctcagc gcctcacgca
    41161 ctaaatccag atctgtttgg tcatcatgaa tggttttttc caaatcctct agctccatcg
    41221 gactcaaaaa acgacccagc tcacgctcaa actcatcaac aagaagtttc aattggttgg
    41281 tgttttgctg ttcatgctca cccttttcat cacgcgccaa tagctggtct aaagtgacta
    41341 atacaggact agcatcaaaa atgatctcaa tctctccagc cagctctatg gttttcatat
    41401 ctaataaccc ctgactggtc aaggaagaaa tagccttatt cacctctgct acagacttac
    41461 ccaaggcatt agcaatctga ctaggtgcca attcgtcaag cctagtcgta ttttggagat
    41521 agaaaaactg ccaaaccaaa aaatcgtctg agctcttaaa aatatccttg taatgaaaca
    41581 gtaaggcagt tggaaggacc aaattgccag actgataatg ctctaaaaaa ctcataattc
    41641 ccctgccaaa cgtaatagcc caacctagct tttaatcagt actgccatta gcaagcactg
    41701 attaaccagg aaaatgcatc aataccttac aatcgtaatc accaatagcc tgacgaccat
    41761 tcaagccgtc cagctcaatg agaaaagcgc agccagcaac aatgccgccc agcttttcaa
    41821 ccagatcaat agtagccttt actgtaccac ctgttgctaa taagtcgtcc acaataagga
    41881 cacgttggcc cggcttaata gcatcagcat gcatggtcaa ggtgtctaga ccatactcct
    41941 tttcatagct agcagaaatc acctctcttg gcaatttacc cggcttacga acaggagcaa
    42001 agccaattcc tagctcaact gcgaccggac agccaataat aaagccacga gcctccggtc
    42061 caacaatcat gtcaatgtcc ttatcgcagg catattgcac aatctcacga atagcatagc
    42121 tgtaggcctt gccactagcc attagcggcg aaatatcacg aaaggtaatc ccctcctttg
    42181 ggtaattctc aattgaagca atatattgtg ttaaatccat cgtaaaatag tctttctaat
    42241 gtcttttaaa ttaaaatctt tcctattata gcatgaaagt ctaaaaaggt aaatgattcc
    42301 taatcatcca gatcaatccc tttttccttt aaattagtca ggcattcctg taaataggcc
    42361 tcttgatgct caggataaat cggtgaggtc agtgccacct cctctaagtc ctcataggcg
    42421 gcaaggcttt ttcctcggta atttttatcc tgccagctca catctggctg gtagccccgc
    42481 gcctgcattt cctgcataat caacaggtga tactggtaaa gcttataaag agaatgggca
    42541 aacacatagt caaccgtcgc atgtggtctc ccccagcctg ctcctcgcaa ggccgcacat
    42601 tcacgatgct gccccaacaa ttgctgcctt ggtaggcgtg tgattaaatc ctgatgccaa
    42661 agacgcataa gctctcctat ttctcttcac tagtcattaa atactgataa atctcctgcg
    42721 gactgcccaa ggccataagc tcttgaaact ttaccagctc ttttagctgt tggtaaatga
    42781 cactgtcagc gatgctacgt tttggggcat cagtctttac cctcatcagc ccatcttcga
    42841 ttactacaaa gcctaactcc tcaaaaattt gtatcatttt gaccaagagg attttttcaa
    42901 tcttgaggta atcacttagc aaggtcagct tatggcgaag atcaaattct gggtattgat
    42961 agatggtctt ataaagcttg gcaaattgct ctctactgcc atagcctgtt aggtaataag
    43021 ggcgcttaat atgattttta aagtaaatcg cttcaaattc ccgatgtcta aaaaggcctt
    43081 tcaaggcatc aatatcgtca ggaacctcat ctatgacaac aaccttggcc tgctggtcct
    43141 caacagctgt aggaatatgc tcaggtgccc tagcagtcct tgctcgaata tcaaacagct
    43201 gcaccccagt cactctagcg tcaaccagca ttaattgcag gctagtatga cctcgccagt
    43261 gattgatcgc aagactaacc gctaattcca agccctgtga ttgctggtac tcctgtatca
    43321 gatgtccctg accaaaggcc aagacatcag cctcaacggc tcctttgctg accttgaact
    43381 tcaagtgact ttgttgctga ccaatggtcc ttgcctgctt aatcgtaaaa tcttttaagt
    43441 aaaaaacagg ctttttatta tccatgccaa agggtgctag aagtagcagc ttgttcagac
    43501 tatctatact caatgcttct aaatccaatt caccattgat caatagagtg tttttttcct
    43561 gaccatcgtg tcccttggct gccacgtatt ggcaaagtag ctctgatagc tcctctaggc
    43621 gatcagatgg cagagtcatg cctgctgccc cctcatgacc accaaaggct gtaaataagc
    43681 tcctattgct attaagtgct tcaaagatat taatgctctc taagcttctg gctgagccct
    43741 tggctagccc ctcatcaatg gtcaaaacaa gaacagtctg cccaatctcc tccatgatcc
    43801 gaccagctac aatccctaag acccctgggt gccagccaga cttagctaaa acctgcacag
    43861 gcttgtctag atcaagcata gccattgctt gagcaaaaat ctcctgtacc aagacctttc
    43921 tttcctcatt tttactacta atcatcaagg caagctcatg aagctcttcg tcatcaaagc
    43981 ctgtcagtag atcaatagct ggatttggat cgtcaagacg ccctagagca ttgagctgcg
    44041 gagcaagctt aaagctaata acatcttcat caaaatgcgc taagtcaacc tctgaaagct
    44101 tcatcagctc ctgcaagcct agtctttctg tctcttttag aacagccagc ccgtttttga
    44161 caaggatacg gttttcacct cgtaggctga ccatatcagc aattgtccca atagcaacca
    44221 gatctaaaaa gtctactgga attgtctcta acagagctga agccaacttg aaggcgacgc
    44281 cacagccagc tagtttttga aagggataag cagcagctgg gtgctcaggg tgaataatag
    44341 caaaggcatc aggtagctct gctggcaggc tgtggtggtc tgttacaata acatctaccc
    44401 cctgtgcttg cgcaaaggca accgcttcat ggcctgaaac accattgtca acggtaataa
    44461 tcagcgaaac ctgctcttgc tcgatgaaat acttgtaaac actttgattg ggaccatagc
    44521 catctgtaaa gcgattaggc aaataaacaa gaggctctgc tcccatcatt tccagcgttt
    44581 ccttgacaat agacgccgct gtcatgccat ctgcatcata atctccgtag accaaaatcc
    44641 tctcaagccc ctcaatggcc tgacgaatgc gatgaacagc tttttccata tcatttagca
    44701 aataagggtc atggagctgt gataggtcag ctgtcaaaaa gctggtaagc tcctcttcgg
    44761 tatgaacacc tcggtcatag atgagctttg cagctgtctg actaagtccc tttgcctgag
    44821 ctagcttaaa gaagccagca tctggctcct tatcagctat ggtccactga tatttggacg
    44881 taatcattta taattaaata cctttcttgc aagataatca gatatagttg gaaacaaggt
    44941 ataacactta tgagcaaggg ctaggctaat aggcagatta atctctcgtt tcttttttcc
    45001 tattgcagca atgatttttt tcgccacagt atccgcctgc agcgtaaagc ctgcaacact
    45061 ggctaaatac tgcccgcttg ggtcagcctg ctcaaaaaag gaggttgcaa tcgggcctgg
    45121 attaacagtt gtcacataaa cctgcctttc tgccagctcc aagcgaaggg cattagaaaa
    45181 gccaatgact gcaaactttg tcgcagaata gatacttgac ttggcagaag ctattaagcc
    45241 tgccattgag acaatattca taatatgtcc agagccctgc tctgccattt tgtggccaag
    45301 caagcgtgca aaatgaatgc tggctaagct attcacacga aacatggcct caatctcttc
    45361 tgcagagaaa tcatcaaagg ccttaaaagc accaaagcct gcattgttaa tcaaaacatc
    45421 aatcctgcca tggcgctggt aaagctcatc aacaagagcc tcaatagcag cagggtcttg
    45481 aatagcaatc tcgtagcatt ccttattacc gcgagcctga tatagactgt ctaacctgtc
    45541 tttgctgcgc cctaacaaaa tcaggtaatc ttctcttgga agctgtctga tgatagcctg
    45601 tgcgagcccg ccagaagcac ctgttatcag aataattctc tgtgccatta aatgatcact
    45661 tcctctaaat cgcgaacaac cttcacattt tcaaaaatag ttgccgcatc cttttccatt
    45721 tgacgacagt cacgtcctaa aaagcgtgct gaaacatgat tcagtaaaag acgcttagca
    45781 cctgcatcac gcgcgatttg agcagcctgc atgtttgtcg aatgcccatg attacgggcc
    45841 attctttcat cacccttccc gtaggtggac tcatgcacca gcacatcagc atcttttgcc
    45901 aatctaacac tagcagatgt cttgcgtgta tcgccaataa tggtgatgat ctttcctttt
    45961 cgaggctctg aaataaagtc cttggcaaaa attttggtgc catcctctag ctcaatatcc
    46021 tgcccatttt taaccttgcc aaaaagtgga ccaaagggca ctcctactgc tctaagagct
    46081 tctgcatcaa gtgttccttc taaatccttt tgaaccacac gataccccat acaaaagatg
    46141 gtatgtgcca agcgctcagc ataaacaata aatttatctg tttctaaaat cttgcccata
    46201 gaggtgtcat caaactcatg ataatgaatc tgataaggca atttagagcc tgatatcctg
    46261 atgctgtttg ttacatagga ttttatccca acaggtccat aaatctcaag gtccgtctgc
    46321 tcctcactag cttgaaaagc ccgactagat aaaaagccag gcaagccaaa aatatgatca
    46381 ccatgcagat gcgtgataaa aatcttcttg atttttcgtg gcttgattgt tgtttctaaa
    46441 atttgccgct gggttccctc gccacaatca aacatccaca cctcattgat ttcatctaat
    46501 agctttagca ctaagcttga aacgttgcga tgcttggctg gctgcccagc tccagtacct
    46561 aaaaattgta attccataca gtctattctt tctaatgcac aaggtaaatc atgaattctc
    46621 tttgtgcaaa ctgataatat ttctttcctt tgaatgcttg gctaagagcc aacaattcat
    46681 cactattaaa gccctttagc agggtcattt cgtttgagaa acgatagatc gtggttaaca
    46741 aagcatgctc aggtgttatg tcctctggct ctccttgctc aaattggcag ctcttcatct
    46801 tgattctacc atcttccaca taaaccacgt attgtggaaa aatctgagcc agctccagca
    46861 gcagcgattc ctcaggctgc ccctgctctt tttcagcaaa aacaatcgcc tcctgtgctt
    46921 cattttcaaa gacaaagcca taggattgcc ccaacaaatt taagcggaca aagggcttca
    46981 cctcatcaaa tgacggctct gaggtaaaca gcttcaaggc ccttgatagc tcaaaataat
    47041 aatctgtcgc tgcttttggt gattgcttct gatacatttc tgcaaaataa gcattaatca
    47101 cacttggggg tggcgtgatg gtagctaatt tttgctggtc tgtcaagccc tttaagcaat
    47161 tttgcaaata aaccgtatct aaactcgtaa agcctccata agtctttgcc aattgaatat
    47221 aatcagtcat aaaattcttc taatctccat ttatttttgg gagcaatgta gccagaaatc
    47281 tcttcaatct ccttatcaaa gctataaggc tccaataacg ccaacctgtt gaggtcatag
    47341 catttgtagg cttgatcctg acagagcttg atcgaaaatg gctcaaacat gtcccgaatc
    47401 tgatcaataa gcaactgtct taagaggcta cgactgtttt tatcacgtgc tgacagcctg
    47461 acatttggaa aaacagttgc agtcaagcta gctgtcttat ccatcttgtt ataaatagcc
    47521 agccttggaa tatccagcat atctaaatct ttcaagatgt ctagaacaac cctctcatgc
    47581 tccaaatgat tagggtcact ggcatcaatc acatgcaaga gcaaatcaac atgccgactt
    47641 tcctctaatg tcgacttaaa agcagccacg agctccgttg gtaaatcttg gataaagcct
    47701 acagtatctg tcagagttgc ctgaaactga ttttgcagat aaatttgctt ggtggtggca
    47761 tcaagtgttg caaataattc atcagcctca tattgcttgt caccagtcaa aatagtcata
    47821 atagtagact tacctgcatt ggtatagccg atcaatccaa tattaaagac atcagaggtc
    47881 atgcggcgat cacgaatcgt ttgacggttt ttttcgacag cagctagctg ccgctcaata
    47941 tctgcaatct gatgacgaat ggagcgccgg ttcagctcca gctggctctc acccggccca
    48001 cgactcccaa tgcccccggc ctgacgacta agcataacac cctgtccgac cagtcttggc
    48061 agcatgtatt tgagctgcgc taaatgcacc tgcaatttcc cttcatggct tctagcccgc
    48121 atcgcaaaaa tatcaagaat cagctgcatg cgatcaatga ccttaatacc taaggcgtcc
    48181 tccaaattgg cattttgccg agccgttaaa cgattgttaa caatcactgt atcaatctca
    48241 ttggcagcaa ccatttcttt gatttcagcc agcttaccag agccaacaaa ggtcttgcta
    48301 tcatagcgct ccctcttttg cagatagcaa tcaacgacct ctgcacctgc ggtcttggct
    48361 agactagcca gctctgtcat tgatagctca gcatggtcag ctgcttgtag gaccacgctt
    48421 agtaaaataa ctctttcctg ccttgccttt gtctctatca tgaacgcgac taatcctcca
    48481 aattccgtag tgtttattat agcatagttt tagctatttt cagctagttt gccatcgata
    48541 gcttcctaag gctccttcaa aaagcgctcc accctatcat atattgcctg cggataggac
    48601 gactcgctaa tcgagtcaaa gcgcactgcc atacggttac gaaaccaagt cagctgtcgt
    48661 ttagcaaagc ggcgtgtttg ctgctttagt gtggctgttg cttcttctaa actagcctga
    48721 ccctgaaagt aagggaagag ctccttataa ccgatccctc gactagcctg aacagctgga
    48781 tactgctcaa aaagccacct tgcctcctcc aataggccag aagccatcat cagatccacc
    48841 cgcttattaa tccgctcata aataacctct cgctcatcag tcaagccaat gatcaagggg
    48901 ttataggggg cctcttgatt ttctaaatcc ctagcaaatt gatttagctc aagtgagcga
    48961 atggcacgcc tgcggttaac ctgatcaagg tgaatgccct tactagctaa tagctgataa
    49021 agctctgtat ctgtcagtgt ctctagctgc tgccgataag caagtagctc cttttgatca
    49081 agatctcctc ctagatgata gccctctaac aggctttgca aatacaggcc ggtaccaccg
    49141 acaataatcg gcagtttacc gcggctaaca atatcttcaa tagctcgctt agcgtcctgc
    49201 acaaaatcaa aggctgagta agactctgtc acctcacgaa tgtcaatcaa atgatgaacc
    49261 gcaagagcct gctccctggc actagcctta gctgtcccaa tatcaaggtg acgataaacc
    49321 tgctgactat ctccagatat aatttcacca ttaaaggcac cagccaaggc aatccctaga
    49381 gctgtcttgc caacagcagt cgggcctaca atcacaatta tcttttcttt tgtcatttat
    49441 tgtctttcta cttaaaaagc agctgaaaaa gtcttttact tgaattttct aatctttttc
    49501 gctaccatat attataacat aagattgaga gacagttatg gtcctcttaa tagaaatgga
    49561 gaatgattat ggctaaaaaa catggattcg caaagggtct tgctacaggt gttcttgcta
    49621 ctgctgctac cgttgcaggt gcagtatttg ctgttaaaaa gactattatt gaccctgagg
    49681 aagaaaaagc agcatttgta gaggaaaatc gtaaaaaagc agcacgtcgt cgtgttgctc
    49741 gctaatcact aatagatgaa agattcgaca ggctttatca atagcctgtc gaatttttta
    49801 tgctgtgaga ccaagctttt tgcttagaca cataaaagaa acagctcgtc agcgccgcat
    49861 actgcctact tcattgacca acaaacaggg caaactaagg ctaattttca ctgatatgac
    49921 atgtttcgac tataaagcgg ttttgtgatt gattgatcac aatatcaaat tgctggtgat
    49981 aagggtgcag ataacgagca tattgagcgc gcctattgac atgatgaact ccggattgcg
    50041 acctctaacg ctagtatctc taccaagccg cctttggagc tctgtgtcac catctgtata
    50101 aaagtaaagc gataagtcaa acaactctgg ctctaaaaag gttgtcgaca tgccttcagc
    50161 aataaggatg ggcacattcc ccttcaccaa aaaagaggga gaccaagggg tatcaatact
    50221 caaaaaatcc agtccttgct taaacatcat gatgtcacgc ctcagactgg ccaattcgtg
    50281 cctagcaggg tgacaggctg ttatactacc aagtacctcc tctccctgat cagggtagct
    50341 aatcaaaaca gcctgactaa aatcattagc gatgatatag gcatctgttt ctaacaattg
    50401 gctttgtcca tcaggcaaaa gctgctgtaa gcgcttagca aaggttgatt taccagatgc
    50461 accatgacca ctaattctaa taagcatttt ctcacgattg gctgctgcag ttacaatagc
    50521 ttgaagtagc ttctccatta tctctcctca tcaaataaca ttctaataat aggacatcat
    50581 tctacatcga aaaacaagcc ggtctcccga aacagcctga ctgacagtaa aaaaagattg
    50641 aagggcaatc caataaggaa agcttctcca atctgattaa tagtctataa tggcttaata
    50701 tgagtgccaa atgtcttggt tatattgttc aatcgtacgg tccgatgaaa agaagccagc
    50761 cttagcaata ttatgcacaa cctttgtcag ccataggtcc tgattgtcat aatcagccag
    50821 catttgttct ttgactgcaa tgtattcctc aaggtcaatc aaggtcataa accagtcctt
    50881 agagattaac tccttataga gacggtcaag acgttcctca ttaccaagct ctaataattc
    50941 tggactgata ataaagttaa ctgcttcctt gatagctggg tgggcatcat aatagtcttt
    51001 agacacataa ccacctgtgg cataaagatc aataatggta tctgaatcct taccaaaggt
    51061 gtagatatta tccataccag caagctcagc gatttccaca ttagccccgt ccatagtacc
    51121 aagcgtcaag gcaccattga gcatgaattt catattacca gtacctgaag cttcctttga
    51181 agctagagaa atttgctctg aaatatcagt tgcaggaatc aaatgctctg ctactgtcac
    51241 attgtaattt tcaacaaggt gaacattaag gtatggactt acctccggat cgttattgat
    51301 aagctctgac aagcaaagaa tcaaatgaat aatatcctgt gcaatgatat aagccggtgc
    51361 agccttacca ccaaagataa ctgttatttt acgcttcggc aggttgcctt ttttgatctc
    51421 taagtattta tgaatcacat aaagggcatt catctgctgg cgcttatatt cgtggaagcg
    51481 tttaatttgg gtatcaatga ttgaatgctc atcaagctca attcccttat tatccttgag
    51541 gtagcgcttt aaggctactt tattatggtg cttaatttca gccaatcttg catgaacagc
    51601 ttgatcctca gcaaaggcca ttaatttttc aagccttgtc gcatcagtca agtaagcatc
    51661 accgataagc tctttaatat agtccgccaa ctcttggttg gcgaattcta gccaacgacg
    51721 gaaggtaata ccattggttt tgttgttgaa tttttctgga tacagctcat agaaggcctt
    51781 caattcgcta tttttcagga tttcagtgtg aagggcagca acgccgttga cacttgtggc
    51841 aaaatgaata tccatatgtg ccatatgcac gcgacctgtt tcatcaatga tttggacagc
    51901 tggatctgat acccttgcac gaacaagagc atctaattgc tcgataatcg ttaccagctg
    51961 cggcacaacc tcattaagga agtcaagagg ccatttttcc aaggcttctg caaggatcgt
    52021 gtgattggtg taaccaacca tcttttgaac cactgaaaca gcctcatcaa aatcaaagcc
    52081 atgcttttgt gtcaatagac gaatcaattc tggaatgacc attgatggat gggtatcatt
    52141 gatctgcacg tatgcgtaat cagctaagtc atgcaggttt gagccacgct caagcgcttc
    52201 atcgatcaag agctgagcgg cattagatac catgaaatat tgctggtaaa tgcgaaggag
    52261 ctcaccattt ttatcagaat catcagggta aaggaacagg gtcaggtttt tggcaatgtc
    52321 agtcttatca aatgaaatgc catctttaat caagccataa tcaacccctt caatatcaaa
    52381 aaggttaaga tagttcttgg tgtcacgctt atagcccaaa acatcaatac ggtctaagcg
    52441 agatttcagg gtaaagtttt taaagggaac atcatatgaa atgtcagtcg gtactagcca
    52501 agagtcatcc tctatccaaa aattaggctc tgctgtttgt tcattgtgtc taaagacctg
    52561 cttgaacaag ccacaatgat aattcaagcc aaccccttca ccattaatgc caaggcttga
    52621 gatagaatca ataaagcaag aagccaaacg accaagacca ccattaccaa gcgatggctc
    52681 caattcaacg tcctctacct cagcaattga tttgcccgca gcagccagct cctctttgat
    52741 gtccttataa atacctagat taatgagatt attagaaagc aacttaccaa tcaaaaattc
    52801 tgctgagatg taataaacct tacgtttagc tgtgtttttt gcttttttgc ttgcttcttc
    52861 tttgagatag gaaagcaacg aaagatagat ttcctcgttg cttgcacttg caagagattt
    52921 tcctaatgtc atttcagtat aatctgtaaa gcgtttcatg atatcctctt ttcaatatag
    52981 tattctagtg atgattattg gctcgaccgt atagctcagt caaatggatt aaataggcct
    53041 tgtgctctgc tttaatatcg tcctcaagca tgcgccactg ccagttgcca ccgacagtgt
    53101 ttggcatatt catgcggcta tcagctgact tatccagcaa atcctgcata cacaggatag
    53161 cagtatcaca cacagtcgca aagattgttc ttagcatggc cttggtgatg ctttcagcag
    53221 ctgccttatg gatataatga ttaacaaact caacctgctc tgcgctcaag tgctcatacc
    53281 agccattcac cacctcattg tcatgcgtac cagtgtagac aatgcaattg tgatcatagt
    53341 tatgcggcaa atcaaagctt tgacttgtca catcaaacaa accaaactct aaaatcttca
    53401 tgcccggaaa gccagtagat gccagcagct gctcagcctt ttcatcaatg tagccaaggt
    53461 tttctgcgat aattggcagc tcacccaagg cctctcgaac agctttaaat agagcaatac
    53521 caggagctga ctcccaatga ccatttttag cagtcacatc accaccagga atttcccaaa
    53581 aatctgagaa gcccttgaaa tggtcaattc taagcttatc gtacagcttg aagctctctt
    53641 tgatccgatg gatccaccaa gcaaagcctg tttgctcatg gctctcccag ttgtaaatag
    53701 gattgcccca aagctgcccg tcctcactaa agccatcagc aggtacacct gcaatgtaaa
    53761 tcggcttttt atctgcatcc accttaaaga gctctggcat cgtccaaacc tcaacgctat
    53821 cagcagacac gtagattggc atatcaccaa tgatagtaat gccattttga ttagcatagg
    53881 tcttcagcgc tagccactgc tgataaaaga aatattggca gaccttatga taggtgatgc
    53941 ctttggccaa cagcttgcgg taatgaagca aggcagcctc ttcacgctta acaattgctc
    54001 tatcgtccca ttcctggagg gccttgtgat caaaatgctc tttaatagcc ataaattcag
    54061 caaaatcatt tagccagctc gcagttgctt caaattcggc gagctgtctt aagccttcct
    54121 cagttgagac aaaagcctga actgcttttt ctaataaagg gcgtctggct tgaaagactt
    54181 gagcgtaatc aacagactcc ggatttgagc caaaatcaac agcagcataa tcagcttcct
    54241 gcaaataacc gtcctttgcc agcaattcaa ggtcaataaa atgcgtattt cctgcaatag
    54301 ctgaaaaaga ttgataagga gaatctccaa agctagttgt tgttaagggc aaaatctgcc
    54361 aataggtctg cttggtttcc tttaaaaagt caacaaattc aaaggcctct ttaccaaagc
    54421 tcccaatacc gaagcgtccc ggaagcgagc tgatatgcat cagaatacca cttgcacgtt
    54481 tagtcattct ttttttctcc ttgtaaaatc ttaatgttga aattataacg caaccgtttg
    54541 cgcaagtcaa tatcttttca aaaaaaaaga gactttttcg gcatgctaga gctgctcaag
    54601 ccttgataat aatgagggaa gcagctagga caaaaacaaa aaaaggattg gagagacagc
    54661 ctaagcagct gctcttccat cctcatctca ctcctatttg gcattaatat ccctgacact
    54721 ctctcgcttt ttgaggctaa agggaaccaa aattttctga ctcagggttt gttcattggc
    54781 attgataatg tctaagagct gcctaaagga ggttcttccc aaattttcaa cgttaatatc
    54841 aaatgttgtt aagtaagggt gaatcaattt cgaatagcta gaattattaa aggtaataat
    54901 cgaaatatca tctggcacct taatgtcata aaaggacaag agctggacca ttcgcaccga
    54961 caaaacatca ccaatcacga ttaaggctgt ggccttaaag ctacgtatcg tttcaataac
    55021 cttttcgatg cttattggat cctttcgatc aaataacagc atcggtttgt tttccaagga
    55081 taatttcaag cagcccttga gatagccaat atagcgctca gaagctacct ctgcctccat
    55141 atcgtctgtg ataaacagga tctgtcggtg acccttttga tagagatgat caactgcggt
    55201 tttagccatt agctggttgt cattgtcaat ataggtgatt ttgttctcat caccttctgg
    55261 tgcgccaaca atgacaaaag gaatctggtt ggtcatcaaa tagcctctaa caggatcttc
    55321 ttgctcagaa tataatataa taaagccatc aacacgcttt tgcaggtgca ttaacttaac
    55381 ctggctcaat aaatcctcaa cagacatacc tgttgcaatg gaaacagtga aatgatgttt
    55441 cttagcttca ttggtaatgg tcgatagaat ttccataaaa aagggatcac tcaaacgatc
    55501 attagtgata atcggcggaa aaaccaggcc aatattatgt gtcaggccac tagcaagcat
    55561 ttgcgcagct acattcggaa catagccaag ctcgctcata gctcttctaa ccttttcctt
    55621 tgtcttttgg gagatagatc gattatcctt gaggacacga ctgacggtcg aaggattaac
    55681 acctgctttt aaggcaacgt cttttattgt aaccatataa acctcattta atacctgata
    55741 atgacgctat gtcaggcttt ttcacatgta ttttgctttt attatacaat tatctcctaa
    55801 aaaatcaact ctcgccctgc aagaaggcga cataaaaaac tgctgtcctc atgatcgaaa
    55861 aaatgttaaa aaaatcaact ttttttaaaa aaagactaga ctttttctgt aaacggttgc
    55921 ataatattaa gtgtaagaaa tatatcttag gaggaaatcg ctatgaaatc atggcaaaaa
    55981 gttatcgtca gtggggcaag cttgacactt gctagcgcct tattagtagg gtgtgcatct
    56041 ggttcaaagg acaaaacaga aactgcatca ggtactgatt caaaaacaat taagctttgg
    56101 gtaccaacag gagctaaaaa gtcatacaca gatgttgtcg ctaaatttga aaaggactct
    56161 ggctacaagg ttaaggtgat cgagtcagag gatccaaaag cacaagaaaa aatcaaaaaa
    56221 gatgcttcta ctgctgccga tgtcttttca cttcctcatg accagcttgg tcagctcgta
    56281 gaatctggca ttatccaaga agtcccagag gaatacacta aagagatcgc tgatacagca
    56341 actgatcaag ctatccttgg tgctcaatac aagggtaaaa cctatgcctt cccatttggt
    56401 attgagtcac aggttctctt ctacaacaaa actaagctag ctgctgatga tgttgcttca
    56461 tacgatacca tcacgtctaa ggctaccttc ggtggtacct tcaagcaggc taatgcttat
    56521 gctactggtc cattgttcat gtctgttggt aacacattat ttggtgaaag cggtgaagac
    56581 actaaaggaa ctaactgggg caatgaaaaa ggggttgctg ttcttaaatg gatttcagac
    56641 caagcctcaa acaaaggatt tgttaactta gatgccaaca acgtcatgtc tcagtttgga
    56701 gacggttcag ttgcttcatt tgaatcaggt ccttgggatt acgaggcagc acaaaaggct
    56761 atcggtaaag aaaaccttgg tgttgctgtt tatccaaagg taactatcgg tggcgaaacc
    56821 gttcaacaaa aggccttctt gggagtgaag ctctatgcgg ttaaccaagc tcctgctaag
    56881 ggagatacca agcgtatcgc agccagctac aagcttgctt catacctaac aaatgctgaa
    56941 agccaagaaa accaattcaa gacacgtaac atcgtaccag ctaacaagac cgttcaagct
    57001 tcagaggctg ttcaatcaaa cgagcttgca aaaacagtta tcacaatggg atcttcttca
    57061 gattatactg ttgttatgcc taagcttagt caaatgggta ccttctggac tgaaagtgct
    57121 gcaatcctta gcgatgcctt caatggtaaa atcaaagaag gtgactacct tgctaagcta
    57181 cagcagtttg acaaggacat tgcagcaaca aaataagcta tctcatttat aatactatcc
    57241 taaacaagta cagaggtggg ctattttaac gctatccttt ctactcatct ctaaaggggt
    57301 ggaactaagc atcattattt tttcagggct tagtccactc ctacttgttt ttgatatgac
    57361 gtaaagcttg gtgctactta aatttttaat cgcttaaaga tttaggtaac acttagctat
    57421 gtggtcgtta gcaccaaacg cttatgacca cagcatctga acaagagagt caggtaatcc
    57481 tactttcttg tatcctaaca taaaggagaa catatatgac tcaggcaggc ttagcatctc
    57541 aggttactgt aaaagaggct ttaacaaagg gaagcttcga tattaaacta tccgctatca
    57601 tcatgggctt tgccaatttt gctaataaac aattcgtcaa aggaacactc tttttattga
    57661 gtgaggtggt ctttttcatc gcctttgttt cacaaatcat tcctgctatt ggcggcctca
    57721 ttaccctagg aacacaaaca cagggcatga caaccaaaac tatcgacggt atcagcattc
    57781 aggttgctgt tgatggagac aattcgatgc taatgctgat ttttggctta gcctctctga
    57841 ttttttgttt gttatttgcc tatatttatt ggtgtaacct aaaaagcgcc cgtcacctct
    57901 acatgctaaa gcaagaaggg gcaaaaatcc caagctttaa ggaggatttt gttagtctag
    57961 caaatggtcg tttccatatg accttgatga caattccatt gattggtgtg cttctgttta
    58021 cggtacttcc tttgatctac atgatttgct tagcatttac taactttgat cacaatcacc
    58081 tcccgccaaa gtcacttttt gattgggttg gtctttccaa ttttggtaac gtgttaagtg
    58141 gtcgtatggc aggaaccttc tttcctgttt tctcatggac actgatttgg gctgtctttg
    58201 ccacagtgac taacttcttc tttggtatca ttttagcact cttgattaat accaaaggct
    58261 taaaattgaa aaaaatgtgg cggaccttct ttgtgattac catcgcagtt cctcagttta
    58321 tttcactgct gattatgcga aatctgctaa atgaccaagg tcccttaaat gccctgctta
    58381 gcaaattagg gttaatccac cattctctac cgtttttatc tgatccaatt tgggctaaat
    58441 tctctattat ttttgttaat atgtggatcg gtattccatt taccatgtta atcgcaacag
    58501 gtatcattat gaacctgcca agcgaacaaa ttgaggctgc agagattgat ggggcaagta
    58561 aattccaggt cttcaaatca atcaccttcc ctcaaatcct cattatcatg acaccaaacc
    58621 tgattcagca atttattgga aacatcaata acttcaatgt gatctatctc ttaactggtg
    58681 gtgggccaac caattcagcc tattaccaag ctggaaccac cgatctattg gtgacttggc
    58741 tctataaatt gactgttaca gcagcagatt ataatctagc ctctgttatt ggtatcttaa
    58801 tctttaccgt atcagcaatc tttagcttac tggcttacac aagaactgca tcatacaagg
    58861 aaggagcagc gaaataatga aaaacaaacg tcgatttcag cttggattag tttacgccat
    58921 tttaaccgtt ctctcaatca tttggctttt acctatcgct tgggttgttc tgactagctt
    58981 tcgtgctgaa ggcactgctt atgtcgatta ttttcttccc aagcacctca cattagacca
    59041 ttatattaag ctctttacaa atgaaacatt tccttttggg agatggtttg tcaatacctt
    59101 tgttgttgct atctttacct gtatcatctc aacctttatt acagtggcga tggcttactc
    59161 gcttagtcgg atcaaattca agtttcgcaa tcgtttctta aagcttgcac tagtgctaaa
    59221 catgtttcca ggctttatga gcatgattgc tatctactat atcctaaaag cacttggcct
    59281 tacgcaaagt cttaccgccc tagtccttgt ttattctgcc ggtgctgcac ttggatttta
    59341 cattgctaag ggcttctttg ataccattcc ttattcgctt gacgaatctg ccatgattga
    59401 tggggctact cgtatggata ttttctttaa gattacccta ccgctatcaa agccaatcat
    59461 tgtttacact gcactccttg cctttatggg accttgggtt gactttatct ttgcccaagt
    59521 gattttagga gatgcaacca gcagatatac ggtagctatc ggactctttt caatgctgca
    59581 gcctgacacc atcaatgact ggttcatggc ctttaccgct ggatctgtgt taattgctat
    59641 tccaatcaca ttgctcttta tgtttatgca aaaatactat gtagagggcg ttacaggtgg
    59701 ttctgtcaaa tagcagtaat gatcacgata acccttactc aaaaaatcct tccc
//
LOCUS       DARYYD010000003        58403 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.003, whole genome shotgun sequence.
ACCESSION   DARYYD010000003 DARYYD010000000
VERSION     DARYYD010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 58403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58403
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.003"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..600)
                     /locus_tag="TV188_000120"
     CDS             complement(<1..600)
                     /locus_tag="TV188_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1533520.1"
                     /translation="MKRQSNIRRLCHQALAATLITGSLIGTGLLGNKVVYGDMSADVK
                     KIEQVLQSDSGKLKTVLGQISDPNTLFALFAIISADVNIDPESFSFILNGPITPLLSY
                     FNNPNKNDNRKAVVNEIKKRVSALEQAQKLETKAKIEKQIAESELEKTRNAFKVTIEN
                     LHKLEGLLDTEKQKTRKVEEDYQQAKTDKEKAEADKRNAE"
     gene            1005..1649
                     /locus_tag="TV188_000121"
     CDS             1005..1649
                     /locus_tag="TV188_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533521.1"
                     /translation="MPIAAYQYESVVEIISEINRLHYSFSSGLGALLCFNLKKSVSSV
                     VVNNRIDREFQELIVSYKARLNRNISQVSSIRHQFIGIRWRIKQAESISEKLLYYMSE
                     NHEFGRIPLNKCLNDFLGFRILVNNLEVVFAALQNDNRVTNIAKLYLRTDGDYKGIHL
                     YFKNGNNRFFPWELQIWDPEQSRLNELSHKEHKQKRQYISLPQHYFDANLEKEE"
     gene            1654..2403
                     /locus_tag="TV188_000122"
     CDS             1654..2403
                     /locus_tag="TV188_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1533522.1"
                     /translation="MYQHFILVASSYARGERVGFHLATEGQLDHVAIEEKMQRLSHIN
                     RDDVGVHSFVTDSADWQSVIELDSFFEDIMVCQDFDEFEQVLQSDSKISAIDVAKFFL
                     AMRPLSHLQLQKLVYLAYKTYLLAYGESLFDEKIVAFQYGPVVEEVYHSFKKYGSEVI
                     DIDDHTEYILKDIHLPQALGRMLLVEDAKKIVPVLLDVVKQYGDLTGGELVKLTHSEK
                     GPWQTVFRPQLNCEITDEVILAQGRYERLSS"
     gene            complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TV188_000123"
     CDS             complement(2508..2657)
                     /gene="rpmG"
                     /locus_tag="TV188_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1533523.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TV188_000124"
     CDS             complement(2673..2855)
                     /gene="rpmF"
                     /locus_tag="TV188_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEL1533524.1"
                     /translation="MAVPARHTSKAKKNKRRTHYKLTAPSVKFDETTGDYSRSHRVSL
                     KGYYKGHKIAKANAAE"
     gene            3125..3955
                     /locus_tag="TV188_000125"
     CDS             3125..3955
                     /locus_tag="TV188_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533525.1"
                     /translation="MFGKLLSLLGFVVALTGCGVSQAEKERVVTEYSPIIIKKFQTLG
                     YQGKITVDDYTKMIETGSERLYFTYSEEVDGKVISLKDSISIATYKSPEEDLADAEVD
                     MGIREEAMWQQPAVKAQAAQIKQLFSELETEDLKLISVTGQSVQTISDSDGELIREDV
                     VRGRNELSQDASNNREAGLSIGGYYHIDVSKYLKNHVLEIRIDFDWRMSEEEQDDLSG
                     PRLDFSDRIKSLDFTCLWDGYYKVGFDRVSRSNRSGDIQDMIVLDIRGGKLVRSFSVL
                     "
     gene            4015..5295
                     /locus_tag="TV188_000126"
     CDS             4015..5295
                     /locus_tag="TV188_000126"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEL1533526.1"
                     /translation="MKLQKPKGTQDILPVAAAKWQYVEGVARETFKQYHYGEIRTPMF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PVKLYYIGSMFRYERPQAGRLREFHQIGVECFGSANPATDVETIAMAYHLFERLGIKE
                     VTLHLNSLGNAASRAAYRQALIDYLSPMRETLSKDSQRRLDENPLRVLDSKEKEDKIA
                     VANAPSILDYLDEESQAHFDAVRSMLEVLAIPYVIDTNMVRGLDYYNHTIFEFITEVD
                     QSELTICAGGRYDGLVEYFGGPATPGFGFGLGLERLLLILDKQGVELPVEEGLDVYIA
                     VLGAYANVAALALTQAIRRQGFTVERDYLGRKIKAQFKSADAFKAKVVITLGESEIKT
                     GQAVLKHNQTRQEMTVSFDQIQTNFASIFAECIQ"
     gene            complement(5500..6792)
                     /locus_tag="TV188_000127"
     CDS             complement(5500..6792)
                     /locus_tag="TV188_000127"
                     /inference="COORDINATES: protein motif:HMM:NF025854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1533527.1"
                     /translation="MAINAIFHLYTSVVNIVIVNYFFRQKNGQLATFKNIGYLSFLVF
                     IECCTHFFVSGSYASLITLTCSLVTSLIISSSYRYSMKQCIFWSVTLQSIGILLEASL
                     GIILISLKYQISSISGTFLFINLLTISSIIIIFVLKQLFLKTTDNWLDEQTQTNWILK
                     LSIIPMISLSLLLLQLLRLKEEPLFDLFTILLTLGFIIITITSLYLYTYISDQHLQMQ
                     DINLDRVRFQSELKHLENVKENQLSIRALKHDLHNQNIVLLGLLEQKQYTKAQQLLNH
                     NLNLLDGTDTFFTNDTILNYLLNQKAVVAKKNGIVLDIHCLIPTNISLKTEVISVIIG
                     NLLDNSIAATIRNQNKAEKQIQLKVRLFKNQLHIDIENFFDPKELASRSQRKKDGLGI
                     KNVQKIVQQYYGLYQQTIDNNIYKVSIIFSNIVLVSQQ"
     gene            complement(6782..7498)
                     /locus_tag="TV188_000128"
     CDS             complement(6782..7498)
                     /locus_tag="TV188_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1533528.1"
                     /translation="MLKIALCDDNKAFATAVEDLLYQYNQLVPVELDIYEDPCQLIQS
                     LSNDYHIFLLDIEMDNMSGIALAEHIRKDNLSAIIIFLTSHKEYMENIFHVQTFDYLI
                     KPLNEPYFFECLNRALRVLELDKKFFTFSSCHSYYSLSLNDIIYFEKEGRKVLIHTKD
                     KTYSTFLSTKALLKELPEQFIQTHHSYVFNVNYFYKFENNDITLAIDNTRFFIIPISR
                     KFKKGIQENIFSKLRRVNGY"
     gene            7752..7976
                     /locus_tag="TV188_000129"
     CDS             7752..7976
                     /locus_tag="TV188_000129"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533529.1"
                     /translation="MNYSRPCIKDIYPIYKLSDTMFRIGAQINITTEFNDSNYETGAS
                     FTHKLWPHFKECPACGHGNSNDWEIFSHYG"
     gene            7987..8907
                     /locus_tag="TV188_000130"
     CDS             7987..8907
                     /locus_tag="TV188_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533530.1"
                     /translation="MEQYELMVRSLSKRYARDGSYANRDLHCVFKSSEITALIGHNGA
                     GKTTLLNQIIGNIKPDVGDISFLDCSFVKSPKIARKNTSMMPQLHAPLKGITIKQAIS
                     SIGKIRGLSGKLLETEVQELIQELGLIKWQNTVGEKLSGGLKRLTSFAMAVIAAPKIV
                     LLDEPTNDVDPIRRIKLWLYLKKMAAKGHIVIVVTHNILEVEKYADAYYLLEKGEVKS
                     SGAVKTLSSNPKSRISILFRDQKALEEYPFAYSLGGDDNEAITIMDNKEMTALLNWLG
                     IHLSSDTIVQYSITTLGLNDYYEELSDEED"
     gene            8894..9634
                     /locus_tag="TV188_000131"
     CDS             8894..9634
                     /locus_tag="TV188_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533531.1"
                     /translation="MKKISVTYQFLSLLNWSFIRHKSLILLCSVIQFFMTIALVYGYS
                     LIIADDTVQTVYYLASGSVTIGMITIGCTVSAQSISSDKRDGIVSYIQTLPVLRSLIL
                     LSDLLIWTLTALIGVGVSIAVVYLKFQILPQLSLATFLILPLVLMTMISMGFAIAYWS
                     TPSTMMLVTQLLLMIGLLFSPIMYPAERIPEVILRGYHFLPFIPAGDLIRETVYLGHS
                     ISVVKLVVLLLWLVATALLSVNWLNRQS"
     gene            9791..11539
                     /gene="aspS"
                     /locus_tag="TV188_000132"
     CDS             9791..11539
                     /gene="aspS"
                     /locus_tag="TV188_000132"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEL1533532.1"
                     /translation="MKRSMYAGHVRKEHIGRTIVLKGWVSRRRDLGGLIFIDLRDREG
                     VMQLVINPEDVSGDVMATAERLRSEYVIEVEGSVEARQQANDKLATGAVELKVSGLTI
                     LNTAKTTPFEIKDGVEVSDDTRLRYRYLDLRRPEMLESFKLRAKTTHVIRNYLDNLGF
                     IDVETPMLTKSTPEGARDYLVPSRISQGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLSEQEIQDIVEGMIAKVMKDTKGIEVKLPFPRMAY
                     DDAMNHYGSDKPDTRFDMLLQDLTDLVKEIDFKVFSEAQAVKAIVVKGHADRYSRKDI
                     DKLTEFAKQFGAKGLAWLKVVDGAFTGPIAKFLTGVKSKLTESLQLEHNDLVLFVADT
                     LEVANNTLGALRTRIAKELDMIDMSQFNFLWVVDWPMFEWSEEEERYMSAHHPFTLPT
                     AESAHELEGDLAKVRAVAYDIVLNGYELGGGSLRINQKDMQERMFRALGFTAEEANEQ
                     FGFLLEAMEYGFPPHGGLAIGLDRLVMLLAGKDNIREVIAFPKNNKASDPMTQAPSLV
                     SEKQLEELQLQIEHHD"
     gene            11532..12479
                     /locus_tag="TV188_000133"
     CDS             11532..12479
                     /locus_tag="TV188_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1533533.1"
                     /translation="MIKKTTYRKRVKYLINRGAKKIGLLHAVKSISKEKYTEKISASL
                     LYGILSSIAVNFFFQPGHVYSSGATGLAQVISAISHHLWGFEIPVALAFYVTNIPLLV
                     LAWYKIGHKFTIFTFITVSMSSFFIQIMPQVTLTTDPLINAIFGGLVMGLGIGTGFKS
                     RISSGGTDIISLTLRKKTGKDVGNLSLMINGVIMAFAGLLFGWQYALYSMVTIFVSSR
                     VTDAIFTKQKKMQATIVTSCPDKVIHMIHKKLHRGVTSINDAEGTYKHEHKAVLITIL
                     TREEYSEFKWLMLKTDPNAFVSVAENVRIIGRFVESDED"
     gene            12495..13376
                     /locus_tag="TV188_000134"
     CDS             12495..13376
                     /locus_tag="TV188_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1533534.1"
                     /translation="MPANKSLKLKNCCFIILGSAIYAFAFVYFYMANRIAANGLAGLT
                     QVANALFQINPSITGYLINLPLVLLGARLFGRRAMVYTVTGILSLYWFVWLFQQLPLF
                     IDLDHDNLVVSLLAGILGGLGGGIVFRNGGTIGGSDIIAKLIEDRFGLQLNQALLGID
                     IFVIVVSLTYISIPQMMYALIASFMYSRIVHLVQNGGYSARGTFIISDYSQTISQFIM
                     EELGRGVTYLHGEGAYSGREKQVIYVALGRSDVRELKAFIAQVDPNAFVSFFDVNEVN
                     SPEFIATKSKYHKTKKR"
     gene            13520..14434
                     /locus_tag="TV188_000135"
     CDS             13520..14434
                     /locus_tag="TV188_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1533535.1"
                     /translation="MTNLDKWHRVRELLLIAVGVAIYTFGFVNFNMANELAEGGVAGI
                     TLILHAHFGINPAYSSLLFNLPLFMLGAKIFGRRSLALTIYGTVLMSVFIWLWQKVPM
                     ELGLENDMMLVAVVAGLFAGIGSGLVFRYGATTGGTDIIARIAEEKFGAKLGQTLLFV
                     DALVLTASLTYVDLKHMLYTLVASFVFSQMISVVQNGGYTIRGMIIITKQSQAAAQAI
                     LTEINRGVTYLKGQGAYSGHDYNIMYVTLNPTEVREVKRILAELDPDAFISIIDVDEV
                     ISSDFKIRRKNFDKPIEKALQKKSNMLK"
     gene            14606..16000
                     /locus_tag="TV188_000136"
     CDS             14606..16000
                     /locus_tag="TV188_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1533536.1"
                     /translation="MEALSIQHYALDTAEKNLLTIDSLTLNQGERVFIIGDNGAGKTS
                     FLKTIIGESTNYSGFLQVHGDIAYVPQIKSTSPQSGGERAMSYLKEAFQARPSLLILD
                     EPSSYLDHANRDWLINQLKRYRGTLLVVSHDRYLINQLSQKIWLLEHQTIKTYHGNYD
                     DYQRSRQLEEDKQLRAFLEYQRKTNQLKKSLTRKKVQANKMAVKKKSVSRSDWKTNSF
                     AGSYDSQAKAMAKAAKAMENRLTRMKEVNSPRKKAWAKLKKDPNEGALPNTLLHLQEG
                     TLTRDHQLLFDYPGIVIRSHSRIAIIGRNKAGKSSFLDQLAAQALSGFYAQNLRITYF
                     KQDQADLEPDQTAVELISRQSSQDRVTILNYLAMMGIDYDKANQKVAVLSGGERVRLA
                     LVAALLTDHQLLILDEPTIYLDLVAIEALESCLIDYPAALLLVSHDLAFVNKVATEIY
                     EVKDHHLTAYHFED"
     gene            complement(16048..17739)
                     /locus_tag="TV188_000137"
     CDS             complement(16048..17739)
                     /locus_tag="TV188_000137"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEL1533537.1"
                     /translation="MDTKTLIAAEIAKIVPELEQAAIFNLLETPKNSDMGDLAFPAFS
                     LAKALRKAPQAIASDLAERIDASQFEKVAAVGPYVNFFLDKASISAQVLTQVIADGAD
                     YAQQDEGQGRHIAIDMSSPNIAKPFSIGHLRSTVIGDSLAHIFAKMGYKPVKINHLGD
                     WGKQFGMLIVAYKKWGNEAAVQAHPIDELLKLYVRINAEAETDPSLDEEAREWFRRLE
                     ERDQEATELWQWFRDESLIEFNRLYDQLGVSFDSYNGEAFYNDKMDEVLELLEDKGLL
                     VESKGAKVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKRTYDFAKSVYVVGNE
                     QAAHFKQLKAVLKEMGYDWSDDMTHVAFGLVTKGGAKLSTRKGNVILLEPTVAEAISR
                     AANQIEAKNPKLANKEAVAHAVGVGAIKFYDLKTDRMNGYDFDLEAMVSFEGETGPYV
                     QYAHARIQSILRKASFTPATDTSYSLNDPESWEIIKLIQDFPRIIKRAFDNFEPSIMA
                     KFAIHLAQSFNKYYAHTRILEDDPERDNRLALCYATAIVLKEALRLLGVEAPNEM"
     gene            18016..18453
                     /gene="argR"
                     /locus_tag="TV188_000138"
     CDS             18016..18453
                     /gene="argR"
                     /locus_tag="TV188_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1533538.1"
                     /translation="MNKIERQQQIKQLIQAEHIGTQEEIRRLLQKDGIVVTQATLSRD
                     LREIGLLKLRDDRGKLYYSLSEPVATPFSPDVRFYVLKVDRAGFMLVLHTNLGEADVL
                     ANLIDNDAIEDVLGTIAGADTLLVICRDEEIAKRFEKDLAAGL"
     gene            18455..18805
                     /locus_tag="TV188_000139"
     CDS             18455..18805
                     /locus_tag="TV188_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1533539.1"
                     /translation="MPYRESLHQLIAALEKHSSIIAYKEAQQHLLQRTDYNQKAYQMK
                     RHQQDTYLFRQIAKDKAAEESAFKAQQLREDLDHQPLIDDYRDKMQNASDLVRYITGT
                     IEDELNKEFNDGKG"
     gene            18792..21347
                     /gene="mutS"
                     /locus_tag="TV188_000140"
     CDS             18792..21347
                     /gene="mutS"
                     /locus_tag="TV188_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEL1533540.1"
                     /translation="MAKANVSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAVKAA
                     QILEIGLTSRNKNADNPIPMAGVPYHSVQQYIDVLIDLGHKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTAVDSSRPDSPNNFLVAVDFDGKAYGLSYMDVSTGEFFATDLADFAS
                     VKSEIQNLKAKEVLLGFELSEEEQAILVKQLNLLLSFEMTALEDSPLIDHQLTAVELS
                     AAGKLLHYVHQTQLRELSHLQALVHYDIKDYLQMSYATKSSLDLLENARTGKKHGSLY
                     WLLDETKTAMGMRLLRAWIDRPLVTSEAILERQEIIQVFLNAFIERTDLSDSLKGVYD
                     IERLSSRVSFGKANPKDLLQLGHTLAKVPYIKAILEAFNSPYLDKLVNQIDTLPELEH
                     LIRSAIDPDAPATINEGNIIRTGFDERLDHYRKVMREGTGWIADIETKERQASGISNL
                     KIDYNKKDGYYFHVTNSNLGMVPDHFFRKATLKNSERYGTAELAKIEGQMLEAREESS
                     SLEYDIFMRIRAQVETYIDRLQQLAKALATVDVLQSLAVVAEKNHYVRPLFNQESKIA
                     IDNGRHAVVEKVLGVQEYIPNSISFGPQTSIQLITGPNMSGKSTYMRQLALTVIMAQI
                     GSFVAAESASLPLFDAIFTRIGAADDLISGQSTFMVEMMEANHAIKRATPHSLILFDE
                     LGRGTATYDGMALAQSIIEYIHDRVGAKTMFATHYHELTELSTKLTKLVNVHVATLEK
                     DGNVTFLHKIAEGPADKSYGIHVARIAGLPEDLLARADTVLTKLEAQSQARESVLSTT
                     EVRETQQLANQQLSLFTDDGSSSEIIKRLESVDVMNLTPIQAMTVLYELKKLL"
     gene            21494..23476
                     /gene="mutL"
                     /locus_tag="TV188_000141"
     CDS             21494..23476
                     /gene="mutL"
                     /locus_tag="TV188_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEL1533541.1"
                     /translation="MTTIIELPEVLANQIAAGEVIERPASVVKELVENAIDAKSSQIT
                     VEIEESGLKMIQITDNGEGMSHEDLPLSLRRHATSKIKSQSDLFRIRTLGFRGEALPS
                     VASISKLTIKTATADAEHGSILVASGGKIEQLEAVSTPVGTKIKVENLFYNTPARLKY
                     MKSLQAELAHVVDVVNRLSLAHPEIAFTLISDGKQLTQTSGAGDLRQALAGIYGLNTA
                     KKMIDISSADLDFEVGGFVSLPELTRANRNYITILINGRYIKNFLLNRAILDGYGSKL
                     MVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKERELMALISTAISESLREQDLIPD
                     ALENLARSSTRSFSKPEQTSLPLQPSQLYYDPQKNDFFTKETVVSEDSPQGFNHETLV
                     DSGVKQVDNLQLAKTESEAAAPSVKYASRPDPMLSDGEHPGLDVHNKQKLSQMLDRLE
                     NEEQSVFPELDYFGQMHGTYLFAQGRDGLFIIDQHAAQERVKYEYYRDKIGEVDNSLQ
                     QLLVPYLFEFSGSDFINLQEKMSLLNEVGIYLEPYGNHTFILREHPIWMKEAEIESGV
                     YEMCDMLLLTNEVSIKTYRAELAIMMSCKRSIKANHSLDDYSARQLLLQLAQCKNPYN
                     CPHGRPVLINFSKADMEKMFRRIQENHTSLRELGKY"
     gene            23487..24710
                     /locus_tag="TV188_000142"
     CDS             23487..24710
                     /locus_tag="TV188_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1533542.1"
                     /translation="MREFFQLPKQIQIRQFVRFITITLGSSIFPFMAMYYTSYFGAFW
                     TGILMMVTSFTGFIGTLYGGHLSDAIGRKKVIMLGSVASTLGWLLTILANVPKTVLPW
                     LTFVGILLVELASSFYAPAYEAMLIDLTDDSNRRFVYTINYWFINIAIMLGAGISGLF
                     YDRYFLELLIALLIINIVCFGIAYRYFGETRPEHYRFEHGIGILAGFANYRQVFKDRA
                     FVLFTIGTILFSSIWLQMDNYVPVHLKLYFEETDVLGIHLTSSKMLSLMVFTNTLLIV
                     LLMTVINRLTARWRLLPQLVIGSVIFAFGMLLSFTFTGFFAIWCSVVVFTIGEMLNVP
                     ANQVLRAEMMDQSKIGSYTGFVSMAQPLGAILAGLLVSLSHFTGQAGVQLAFVLIACV
                     GLYVIVLSAKMKKKV"
     gene            24712..25308
                     /gene="ruvA"
                     /locus_tag="TV188_000143"
     CDS             24712..25308
                     /gene="ruvA"
                     /locus_tag="TV188_000143"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEL1533543.1"
                     /translation="MYDYIKGQLTKITAKYIVVEANGLGYMITVANPYSFTDCVNQQV
                     TIYLHQVIREDAQLLFGFHSEEEKDVFLKLISVSGIGPTTALAIVAVDDNRGLVNAID
                     NSDITYLMRFPKIGKKTAQQMVLDLAGKFVEAPKEESSKPPKAKQQGNEQLDEAVEAL
                     LALGYKATELKKIRAFFEGTSETAEQYIKSALKMLMKG"
     gene            25318..25869
                     /locus_tag="TV188_000144"
     CDS             25318..25869
                     /locus_tag="TV188_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEL1533544.1"
                     /translation="MKRCAWVPQDNKLYCDYHDLEWGRPVYDDRALFELLCLESYQSG
                     LSWLTVLKKRPAFRSVFHHYDISAVASFSEQEMAAALQNAAIIRHKPKLIATVNNAAA
                     VQRIQQEYGSFSSYLWNFVGGQPIDRLVNDDNPAPAQTALSLKLSKDLKKRGFKWLGP
                     TTVYSFMQAAGLVNDHEENCEFR"
     gene            complement(26305..27150)
                     /locus_tag="TV188_000145"
     CDS             complement(26305..27150)
                     /locus_tag="TV188_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1533545.1"
                     /translation="MRWDYGKIYQAIRKSKGLTQEKICGDFLARSTLARIESGQVIPK
                     FDTMIFLLNQLNMTLEEFRYVCNTYHPSTRQDILNQFYNQVSAVNITELEKLRQKCFN
                     YLKNKNDIPISYILDSVEVMISLRKKGVKNNQDLQELAYKIWNSLVKQDTWYEKDLQL
                     LHTILFHFPIEIIENISQKILDSLAKYKDYRNIKSSEYALLTNLSTIYLYHNLKKECE
                     EITLLTIKLARQLKRYDSLGFSQVRLGICRNDDHLINKGLQLLQLTEETELLETLQHE
                     LKNYR"
     gene            27447..28019
                     /locus_tag="TV188_000146"
     CDS             27447..28019
                     /locus_tag="TV188_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase"
                     /protein_id="HEL1533546.1"
                     /translation="MKKRLAFILVAFGILGFSLGNEVLAADTAPASATMATDSDVSFY
                     NGELLKKYLVQSGDRLYFDYDKAIQDKVSDGVIDMGFLVETISEDYSQQTFTSRKYFK
                     AGWQLYGNYCGPGHNGNHFTLPVIDVLDQGCQNHDSCYRWGAGIGANCECNRQLVNYI
                     KVYRRWMPAHALGVADAIRVYFETVGAIGC"
     gene            28013..28303
                     /locus_tag="TV188_000147"
     CDS             28013..28303
                     /locus_tag="TV188_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533547.1"
                     /translation="MLTLKNIINRYYMYYVFLIVVIWIGMFFVRWDTTVAGVLLYPLI
                     MKQVFIVLGVVAMIMAIISRKIVLGIFGLLCCAAFWINLFLAFYLLPGLLGN"
     gene            28989..30260
                     /locus_tag="TV188_000148"
     CDS             28989..30260
                     /locus_tag="TV188_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEL1533548.1"
                     /translation="MKAELIAVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGD
                     NEERLLSVIDIASQRSDLVILCGGLGPTDDDLTKQTLAKYLGKALVFDEQAGQKLDAF
                     FAHRKQAARTPNNQRQAQLIEGSIALQNQTGLAVGGLITVDRVTYVVLPGPPSELKPM
                     VKNELVPLLSASHASLYSRVLRFFGIGESQLVTALEDLIKHQTDPTIAPYAKTGEVTL
                     RLSTKADNQALADERLNRLEAQLLSIRTVDNQPLRRLLYGYGEDNSLARETFELLKRS
                     GKTITAAESLTAGLFQAQLTDFAGASQVFNGGFITYSIEEKARMLGIPLGELQRHGVV
                     SSFTAEQMAAQARCLTNSDIGIGLTGVAGPEALEGQPAGTVFIGLATKNKVESLKVVI
                     GGRSRLDVRYIAALYAFNMVRKTLLKSENLL"
     gene            30354..31490
                     /gene="recA"
                     /locus_tag="TV188_000149"
     CDS             30354..31490
                     /gene="recA"
                     /locus_tag="TV188_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEL1533549.1"
                     /translation="MAKKVKKNEEITKKFGDERRKALDDALKNIEKDFGKGAVMRLGE
                     RAEQKVQVMSSGSLALDIALGAGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDNHVGLQARMMSQAMRKLSASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGTTQIKGTGDQKDSSIGKETKIKVVKNKVAPPFKVAE
                     VEIMYGEGISRTGELIKIASDLDIIQKAGAWFSYNGEKIGQGSENAKRYLADHPELFD
                     EIDHKVRVKFGLLEDTEESAAADTVAAKADELVLELDDAIEIED"
     gene            31866..32264
                     /gene="spx"
                     /locus_tag="TV188_000150"
     CDS             31866..32264
                     /gene="spx"
                     /locus_tag="TV188_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEL1533550.1"
                     /translation="MIKIYTISSCTSCKKAKTWLNAHKLPYKEQNLGKEPLSREEILA
                     ILSKTENGVESIVSSKNRYAKALNCDIDELSVNEVIDLIQDNPRILKSPILIDDKRLQ
                     VGYKEDDIRAFLPRSIRNIENAEARLRAAL"
     gene            32377..32646
                     /locus_tag="TV188_000151"
     CDS             32377..32646
                     /locus_tag="TV188_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEL1533551.1"
                     /translation="MGFTDETVRFNLDDGDKKQISETLTAVYHSLDEKGYNPINQIVG
                     YVLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLQGNGIDIR"
     gene            32643..33062
                     /gene="ruvX"
                     /locus_tag="TV188_000152"
     CDS             32643..33062
                     /gene="ruvX"
                     /locus_tag="TV188_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEL1533552.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIRINEDKQDFGFDR
                     LAELVKQYQVDRFVIGLPKNMNNTSGPRVEASKAYGDKIEELFHIPVSYQDERLTTVE
                     AERMLIEQADISRGKRKKVIDKLAAQLILQNYLDCNY"
     gene            33072..33371
                     /locus_tag="TV188_000153"
     CDS             33072..33371
                     /locus_tag="TV188_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEL1533553.1"
                     /translation="MTHNHDHEHEVITLVDEQGNEALFEILLTIDGREEFGKNYVLLV
                     PAGSQEDESGEVEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFLDEE"
     gene            33919..35478
                     /locus_tag="TV188_000154"
     CDS             33919..35478
                     /locus_tag="TV188_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2079 domain-containing protein"
                     /protein_id="HEL1533554.1"
                     /translation="MSQLHQEVMLEKVNYLVKDHPSSHTTKYDMKVPSLYKFYIFFFS
                     IIASLLTVAVPFFADTANSVQSQNLYIGMMLTKGQIPYSDLFTTGGFLFFVLIALSYH
                     LGTTVWLVLVQALCFYLTGVYFYKLIHYVTGIQKVALGFTAIYYLLSISLGFGGLYAI
                     QLALPFVLVSLWFLTKYFAGLVKDEAFILFGFAAAIAMLIEPRTLLFWLLACIAIIAY
                     NVSQKHFARGFYQLLAAIFGMLLVFYTAGYFILNLQILSPYLEQALVYPFSYFVTGDL
                     SLILGLTVQLGLVLGLGLLTGLLTFMKQPKLESDLAMKWLLVFVVFSYAGIAAISHDF
                     HTYHLLPLLPYALILLSSSVGRQYEAGLRMVSHRRRKGKNGARRVIAIYLNKHFYVPA
                     IIMLGAVFGTAYQYVTSSAINQERSQIAHYLRQRLTEDQPIYVWDDTSKIYLETQAKS
                     ASQFASPFVNLKKESHQQMLEDELLQNKAVYIVVNKQKALPKAVKKIVTANYKIDRKI
                     DVKGFSLYQKK"
     gene            35575..37773
                     /gene="nrdD"
                     /locus_tag="TV188_000155"
     CDS             35575..37773
                     /gene="nrdD"
                     /locus_tag="TV188_000155"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011529096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEL1533555.1"
                     /translation="MITLEKDKVIVQPAIKVIKRDGRLVNFDATKIYSALLKASMKVT
                     RMSPLVEAKLEAISERVIAEIIERFPTNIKIYEIQNIVEHELLAANEYAIAKEYINYR
                     TQRDFARSQATDINFSIDKLIHKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLKL
                     LPAHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLANGFKIGNAEVESPKSIQT
                     ATAQISQIIANVASSQYGGCTADRIDEFLAPYAELNFKKHMADAEKWVIEELRESYAF
                     EKTKKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSWFEREIQKAILTIRINGL
                     GSEHRTAIFPKLIFTVKRGLNLEPDSPNYDIKTLALECATKRMYPDMLSYDKIIELTG
                     SFKSPMGCRSFLQGWKDEQGQDVTSGRMNLGVVTMNLPRIAMESNGDMDKFWELFNER
                     LHICKDALVYRVERVKEATPANAPILYQYGAFGKRLAKTGNVDELFNNRRATVSLGYI
                     GLYEVATVFYGGQWEHNQEAKDFTITIVKEMKKACETWSDEYGYHFSVYSTPSESLTD
                     RFCRLDTDKFGVVADITDKEYYTNSFHYDVRKNPTPFEKLDFEKAYPAAGASGGFIHY
                     CEYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDKCYECHFEGDFTPTERGFTCPNCG
                     NNDPKTVDVVKRTCGYLGNPQARPMVNGRHKEISARVKHMNGSTIKYPGI"
     gene            37879..38025
                     /locus_tag="TV188_000156"
     CDS             37879..38025
                     /locus_tag="TV188_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533556.1"
                     /translation="MGKYQLDYKGMQQVERFHEKHSVAKTDKKSRVQQLRAQFLEKAK
                     QSKK"
     gene            38053..38988
                     /locus_tag="TV188_000157"
     CDS             38053..38988
                     /locus_tag="TV188_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1533557.1"
                     /translation="MLDIGIVGLGAISQKAYLPYMRQLRGINWHLSTRNALVRQEVGQ
                     LFGCARLYSTVNELLEAKLDGVFIHAATKAHLELASLFLQKGIPVYMDKPLTEDFFST
                     QALYQLADKHNTFLMADFNRRFAPGVKKLSTLSTKRKVVVEKNDINRPGDKQFKLFDF
                     FIHPLDTALFLVDRRLVAGYFHYQLTDNDLLSQVSVTLRTEQTIISAAMNLQSGSRRE
                     VMEVQTPKETYHLENLETLRAYRGVDQEIKGFSAWDTTLSKRGFEAIVDSFLQAVKDG
                     VNPVKPETSLLSHWICHQICQSHEADGILDVSLPL"
     gene            39001..39495
                     /locus_tag="TV188_000158"
     CDS             39001..39495
                     /locus_tag="TV188_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1533558.1"
                     /translation="MKLRRPKKQDEASVLEMMAEFEDYQSPHDGGFWNAEHFDYEKWL
                     ESNALMEAGLAIPENWVPAIQLVAFADQQAIGFVNVRLRLNEQLLVKGGHIGYSVRPS
                     QRGKGYAKLMLKEALQLARQKGIREVLVTCHCSNSASRSVILANGGQLKDCNKGIERY
                     WIKA"
     gene            39505..40119
                     /gene="nrdG"
                     /locus_tag="TV188_000159"
     CDS             39505..40119
                     /gene="nrdG"
                     /locus_tag="TV188_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEL1533559.1"
                     /translation="MKENCWNSPKPKEWTSEALSQGRVIDYKAFNFVDGEGVRNSLYV
                     SGCMFHCKGCYNAATWSFKAGIPYTKELEEQIMTDLAKPYVQGLTLLGGEPFLNTGIL
                     IPLIKRIRKELPEKDIWSWTGYTWEEMMEETQDKLELLSMIDILVDGRFDITKKNLML
                     QFRGSSNQRIIDVKKSLAAGEVVIWDKLNDGDQSFEQMSRDDLI"
     gene            complement(40577..41308)
                     /gene="yaaA"
                     /locus_tag="TV188_000160"
     CDS             complement(40577..41308)
                     /gene="yaaA"
                     /locus_tag="TV188_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEL1533560.1"
                     /translation="MLTFLIPTAKEMKPVPPCYPHQLPQKSLPILEAMAELSLEELAR
                     AYSIRIEAASKEAKRLKAIAQGQSSAYPAYQLFNGLMYRHLKRDNLSKDQQDYLSKQV
                     YITSSFYGIIPTDEKIAEHRHDFHTKVTINGQSLKHYWRPIYDQFAKDHKQIISLLSN
                     EFRDVFSKEYQKLWISPKFMEERSGQLKTHSTISKKARGAFLTACLENNVQTKEALKQ
                     LSFAGFCYNEELSTETNYYYIKKES"
     gene            41756..41959
                     /locus_tag="TV188_000161"
     CDS             41756..41959
                     /locus_tag="TV188_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1533561.1"
                     /translation="MENRIQELRKSRGISQADLADMMCVTRQTIISLEKGRYNASLEL
                     AYKLATFFNLTIEDVFLFEEKGE"
     gene            41961..42414
                     /locus_tag="TV188_000162"
                     /pseudo
     CDS             41961..42414
                     /locus_tag="TV188_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516426.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            42424..43098
                     /locus_tag="TV188_000163"
     CDS             42424..43098
                     /locus_tag="TV188_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1533562.1"
                     /translation="METKHSAVKVIISKLKWFGLALLVFMLEQAPTFLITKEQPMWQT
                     LLLVVIFLLISGGTYYLAVKLHIVGDQAIPKNDYRALWIGLGVVAVFVVKMIGGILLF
                     LEHGPGANTVNQAALEQAGLSPILMVTLVAIVAPIVEEIAFRGLLYGKLFGAESYLGL
                     IFSSIMFGLIHVPTDFGSWFIYGGMGLVLGFVFHKTKKVEYTILIHFLNNALAVLIML
                     LLPYLQ"
     gene            43128..43565
                     /locus_tag="TV188_000164"
     CDS             43128..43565
                     /locus_tag="TV188_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533563.1"
                     /translation="MKNDRWIDKKYQRWEKVYKRLGHSLLTIGVLVGTYGIFLIIQGN
                     HQTGFLLFILGPILLIASCLCYYVFTEPTSLREYLINSYDERNRAIRQKAQAYCFCLF
                     AFLFLMLAIFFPNMTIKELFGYNLPLIVFNLYVMIRAWVSKHM"
     gene            complement(43788..44561)
                     /locus_tag="TV188_000165"
     CDS             complement(43788..44561)
                     /locus_tag="TV188_000165"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEL1533564.1"
                     /translation="MKIGFIGVGKMATAIIQGLTHTPHELIISGSSLARSKEIAGQLH
                     LSYAQSHQELIDQVDFIILGIKPQLFETVLSPLQFKQPIMSMAAGISLDRLAQLTSSH
                     LPLLRIMPNMNAQILQSTTALTGNDLVTADLLATAKELTNSFGTTFEIAEKDFDTFTA
                     LAGSSPAYLYLFIEAMAKAGVKNGLPKDKALSIVSQTVLASAKNLLVSTDSPHDLIDK
                     ICSPGGTTIAGLMDLEKTGLTHSVCSAIDTTIKKAKDLS"
     gene            complement(44645..45712)
                     /gene="pepA"
                     /locus_tag="TV188_000166"
     CDS             complement(44645..45712)
                     /gene="pepA"
                     /locus_tag="TV188_000166"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEL1533565.1"
                     /translation="MIDLFSKIKEVTELDGIAGYEHTVRDYLRAKITPLVDRVEVDGL
                     GGIFGIKESKADQAPRILVAAHMDEVGFMVSEIKADGTLRVVEIGGWNPLVVSSQRFT
                     LYTRAGQAIPVISGSVPPHFLRGANGAASLPAVSDIVFDGGFTDKTEAESFGITPGDI
                     IVPQSETILTANKKNIISKAWDNRYGVLMVTELLEALKDQTLHNTLIAGANVQEEVGL
                     RGAHVSATTFDPELFFAVDCSPAGDIYGNLGHIGDGTLLRFYDPGHIMLKNMRDFLLT
                     TAEEAGVAFQYYCGKGGTDAGAAHLKNGGIPSTTIGVCARYIHSHQSLYALDDFVEAQ
                     AFLQAIVKKLDRSTVDLIKKY"
     gene            46057..46404
                     /locus_tag="TV188_000167"
     CDS             46057..46404
                     /locus_tag="TV188_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEL1533566.1"
                     /translation="MAEIVSFCSSLLFPFCDKMKGMNGKKTRIVSGLIGLGLLAGLGL
                     RLKEVYQERERQRVLVELRAFFSALGEIEVLYINSFSSKRDDVTGGLVMTDGKTYTYH
                     YHKGSIDFKEDLT"
     gene            46401..46718
                     /locus_tag="TV188_000168"
     CDS             46401..46718
                     /locus_tag="TV188_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEL1533567.1"
                     /translation="MIIPTSKEELARLIETEPRLVLFFTADWCPDCQYIYPVMPELEA
                     ENPDMTFVRLDRDDFIDLAQDWQIFGIPSFLVMEKGQEKGRLVNRLRKTKAEISDFLA
                     AYH"
     gene            46733..47359
                     /locus_tag="TV188_000169"
     CDS             46733..47359
                     /locus_tag="TV188_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEL1533568.1"
                     /translation="MIFAYNKEQVGDVLMVILEDKKDIKRQVERKGRVARVFAEETGQ
                     TLAWNIFEASALIAVEGNGQVFLSEEELAILNAELAQEGFTERLEASPAPVFVVGQII
                     EMIPHPDSDHLNICQVQIAPDKAVQIVAGAPNAAVGLKTIVALPGAMMPSGSLIFPGK
                     LRGKESFGMMCSPRELALPNAPQKRGIIELGDAAAVGEAFDPAKHWQS"
     gene            complement(47662..48375)
                     /locus_tag="TV188_000170"
     CDS             complement(47662..48375)
                     /locus_tag="TV188_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1533569.1"
                     /translation="MTINLKAYQDMLTRPWGKLMYDLIFAQLGPIAGKTILDFGAGFC
                     ITAEALAVQNEVTAIEPNPDLLFAQKQESIHKIKGSLEALEKLPDQAFDMIICHNVLE
                     YIAPKEHAIYLAQMERLLKPKGQLSLIKHNQVGKVLHSVIFEHDYDKALNVLNGQAFE
                     SLSFAAGQTYSIDDLLRKTDLKLQGYRGLRTCYGLQPNEVKAKPDWLEVLRTIELAIC
                     DQKPYKDMAFFQHVTLSKA"
     gene            48487..48882
                     /locus_tag="TV188_000171"
     CDS             48487..48882
                     /locus_tag="TV188_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1533570.1"
                     /translation="MYNKVILIGRLVAKPELNKTLTDKQVVRFTLAVNRRFKTTTGER
                     EVDFINAVAWGGLAETLASYASKGSLLSLDGELRTRKYDKAGQTHFVTEVLCHSFQLL
                     ESRAQRAIRENNAANDLIDLALEEEKLPF"
     gene            49329..50303
                     /locus_tag="TV188_000172"
     CDS             49329..50303
                     /locus_tag="TV188_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1533571.1"
                     /translation="MRFKQLSLTAFIGLLAMLLTACRQETNQTHQAARVGIIQYAEHS
                     ALDAAREGFIEALEQGGFREGKNLTITTKNAQGDQANLQTMVEQLAGKNDLQLAIATP
                     AAQALLNMDSETPAVFTAVTDPVSAGLVDTLAKPGGNMTGSTDATDVENQIDLLTKAL
                     PQARTVGIFYNSSEVNSEIQAKKAKRELEKKGLKVLMKTVTTTNDVQQVMTSLASQVD
                     AVYLPTDNTVASTATTIGDILKEAKIPSMGSDAAYLSAVLFTSGVDYHAIGMQAGQQA
                     VDILKGKKPASIQVAKPQKASIAVNDDMARLLGIDPEVIKALASNGAN"
     gene            50321..51283
                     /locus_tag="TV188_000173"
     CDS             50321..51283
                     /locus_tag="TV188_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1533572.1"
                     /translation="MKKGSYLILLVLAGFVLVACRSTASPRKVNQSHVNIGILQYMEH
                     DSLTAARRGFEAQLKAAGYTKGDKLSLHYQNAQGDQANLQTISEQLVKQNDLILAIAT
                     PAAQALATVSSDRPIVFTAVTDPISAGLVDRIKKPGGLITGTSDQAPIAKQIDLLAQA
                     LPEAKTIGILYTASERNAEVQVKEAETLLTKVGYRVIKKGIATSNDVQDTAASLMRAV
                     DALFVPTDNTVASTMTMLGELSLANKVPIIGGSTDMVDAGGLLTYGIDYESLGRQAGE
                     MAIKILRGQDPASLAVEYPKTVKLHINQAMADKLAIDTSTLSVD"
     gene            51398..52282
                     /locus_tag="TV188_000174"
     CDS             51398..52282
                     /locus_tag="TV188_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533573.1"
                     /translation="MSLILSSLSQGLLWSIMAIGVYLTFRILDIADLTAEGSYPLGAA
                     ICATGIVSGVSPLLATFLAFIGGLLAGLVSGLVHTKLKIPALLTGIITLTGLYSVNLK
                     VLGRANVALLRQRTLVTQLYDLGFTKLAAVLIMGFVFVTIVIFLLALLMKTQLGLALR
                     STGDNNPMSEANGIKTDQMKIMGYMLSNGLIALCGALLCQNNGYADLNAGVGTIVIGL
                     ASIIIAEVMIRQLSIGWRLASIVLGSIVYRLIILAILAIPGMDADLVKLFSAMLLAAV
                     LFVPELQQRLRLRKTSLG"
     gene            52291..53094
                     /locus_tag="TV188_000175"
     CDS             52291..53094
                     /locus_tag="TV188_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1533574.1"
                     /translation="MSAILSIKAIHKTFEAGTINENHVLRGLSLDIEEGDFISVIGGN
                     GAGKSTLMNTLAGTLAFDQGDILLEGKSIKHLSAAKRAKDISRVFQDPKMGTASRLTI
                     EENMAIAYRRGKSRGLGWGVKERERQIYRQALQELGLNLENRLKAETQFLSGGQRQAL
                     TLLMASLAKPKVLLLDEHTAALDPKTSTMVMALTKQLVETHGLTTLMITHNLENAIAY
                     GNRLVMLHQGNIVVDIKREEKAKLTVDHLMALFHQNSGHTLLDDALVLG"
     gene            complement(53193..54197)
                     /locus_tag="TV188_000176"
     CDS             complement(53193..54197)
                     /locus_tag="TV188_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533575.1"
                     /translation="MLSRHNIVQRSLVKHLLLLATLLGSLGLGNSLSKADSQDHLHVN
                     LYLIQSDSNLKRYGKRIIDKAIEKVKARPRLKFSSEYEVNQFLNNISRLHPELRLTEQ
                     ETQSNKQQTPSKETRRAEASRNSNTSRPAASLSSYRRYSDAQILANIKAELEKSDYDA
                     IKQFKDDFINRLHSQEIQLNPYRDSSKIPALLFRELQYYLKLHPEMIYHLDGINLSPE
                     VADSFVSRLANAYSLDNMLSILQEARAYGQGIIDTIAKRAEAKAILTEHKNTYKDRNQ
                     RVSEDYYSTAFHEIDEAITIQQLNKAIEIVENEAYRIRNKSFDYNRRHHGFITLRKIS
                     "
     gene            complement(54483..55124)
                     /locus_tag="TV188_000177"
                     /pseudo
     CDS             complement(54483..55124)
                     /locus_tag="TV188_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635233.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
     gene            complement(55145..56122)
                     /gene="dusB"
                     /locus_tag="TV188_000178"
     CDS             complement(55145..56122)
                     /gene="dusB"
                     /locus_tag="TV188_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEL1533576.1"
                     /translation="MTRLNSPFRIGHVEIPHRTVLAPMAGVTNSAFRTIAKEFGAGLV
                     VMEMISEKGLLYNNEKTLHMLHIDDNEHPMSIQLFGGDAEGLKRAADFIQSHTKADIV
                     DINMGCPVNKVVKNEAGAKWLRDPDKIYHIIQEVTSVLDIPLTVKMRTGWADSSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGTCDHETLARVSRAITRIPFIGNGDVRTVQDAR
                     FMIEEIGVDAVMIGRAAMNNPYLFTQINHFFETGEVLPELPFAKKLDIAKDHLKRLIR
                     LKGEAIAVREFRGLAPHYLRGTAGAAKIRSAVSRAKTLAEVETIFAQIH"
     gene            complement(56109..56981)
                     /gene="hslO"
                     /locus_tag="TV188_000179"
     CDS             complement(56109..56981)
                     /gene="hslO"
                     /locus_tag="TV188_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEL1533577.1"
                     /translation="MDKLIKTISASGAFRAYVLDCTETVRYAQERHHTLSSSTVALGR
                     TLIANQILAANQKGDSKVTVKVIGDSSFGHIISVADTKGHVKGYIQNPGVDIKKTATG
                     EVLVGPFMGQGHFVTITDYGTGNPYTSTTPLITGEIGEDLAYYLTESEQTPSAVGLNV
                     LLDQEDKVKVAGGFMLQVLPGASVEEISHYEKRIQEMPAISTLLASENHIDALLAAIY
                     GEEPYKRLAEEQLSFQCDCSRERFASALMSLPKADLLTMLNEDKGAEIVCQFCGTKYQ
                     FDQTDLEVLINDKA"
     gene            complement(57231..>58403)
                     /locus_tag="TV188_000180"
     CDS             complement(57231..>58403)
                     /locus_tag="TV188_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HEL1533578.1"
                     /translation="HNLSQLPVLVLSQNLELLQAYDDEERRFPYYELIKTLDIPSNTE
                     LTCYEGTLEESSLMFPIGDKFIFIGPFYTSFFQDSYKEELADSFLKRYPDKSKKELVG
                     YISTIPHFPASHIRSLLIAVDAFFDTNFEMSCQQSINDLLEEAQLIWEDPHIIANLEL
                     ENTPSFHVPAVLNYLNHIIDLVKLGNTELLKHEINCIPSSDVVSSSIPALRAEKNLSI
                     IYFIKLLELSFTENTDVAKNYERIKHFMNLTEKATDLLKVLQIRAAAIISLSESLTNK
                     SVSDKQQIYNSILYYVDKHLYSKLKVSDIAKHLYISESHLRAVFKMYSSISLQTYILK
                     EKVQEAKLLLRRGVPAGEVAKLLYFYDTTHFLKTFKKYTDTTPHDYLAHYQQSITK"
BASE COUNT        16831 a        10319 c        13186 g        18067 t
ORIGIN      
        1 ttccgcattc cttttatcag cctctgcttt ttctttatcg gttttagctt gttggtaatc
       61 ttcctcaact tttcgagttt tttgtttttc agtgtctaat aatccctcta gtttatgtaa
      121 attttcaatt gttactttga aagcattcct agttttttct aattcacttt ctgcaatctg
      181 tttctctatt ttagctttag tttctaattt ttgagcttgc tccaaagctg agactctttt
      241 ttttatttca ttaacaactg cctttctatt atcatttttg tttggattgt tgaaatatga
      301 taataatggt gtgattgggc catttaatat aaaactaaaa ctttctggat ctatatttac
      361 atcggctgat ataatagcaa ataaagcaaa caatgtattg ggatcactaa tttgtcctaa
      421 tactgttttt aacttaccac tatctgattg taaaacttgc tcaatttttt ttacgtccgc
      481 actcatatct ccatacacaa ctttatttcc aagtagtcct gttcctatca ggcttcctgt
      541 gatgagagta gctgctaggg cttgatgaca caagcgtctg atgtttgatt gtcttttcat
      601 gatttagtcc tcacatatcg tcgaatgttt tttctaaaat tcttccaaaa aatcttaaca
      661 tgacgcttgc aggctgtgaa tacgttttgg gcaattcgcc tccgtagttt cgtttttttt
      721 aattcaatca ttaaacgtct gattttatca tgatataatt gatcttgttc aaggctgatc
      781 aggaaattct tgatgaagat gacagcttta tatcggtgtt tgggaaacca taagattggc
      841 aaggctacgc tgggcttagc tgacattgtt gcttcaaaat gctttcaggt gtagaaatgt
      901 tgacaagtat tctttaaaaa gatagactat agctagtagg atagaggtat gcacaggtga
      961 cagatgtgat acttgtgttt tttgctattt ttggaggttt ctgattgcct attgcagctt
     1021 atcaatatga aagtgttgtt gagattatta gtgaaatcaa tcgattacac tattcatttt
     1081 cttcgggttt aggagctctt ctatgcttta atttgaaaaa gagtgtcagt tcggtagtcg
     1141 ttaacaatcg tattgatagg gagttccaag agctcatcgt ttcttataaa gcaaggctaa
     1201 ataggaatat tagtcaagtc tcaagcatac gacatcagtt tataggcatt agatggagaa
     1261 taaagcaagc agaatctatt agtgagaagc ttttatacta catgagcgag aatcatgagt
     1321 ttggaaggat tcccttaaat aaatgtttga atgattttct tggatttagg atcttggtca
     1381 ataacttaga agttgttttt gctgctttgc aaaatgataa tcgagtgact aatattgcta
     1441 aattgtattt aagaacagat ggcgactata aaggtatcca tctatatttt aaaaatggaa
     1501 ataatcggtt ttttccatgg gaattacaga tttgggatcc agagcaatca cgcttaaatg
     1561 agctgtcaca taaagagcat aagcaaaaac gacaatatat atcactaccc caacattatt
     1621 ttgatgctaa tttagaaaag gaggaataac cgcatgtatc agcattttat tttagttgct
     1681 agttcatatg caagaggtga gagagttggc tttcacttag cgacagaagg tcaattggat
     1741 catgttgcca ttgaagaaaa aatgcagcgg ctgagtcata tcaatagaga tgatgttggt
     1801 gtgcattctt ttgttacaga tagtgctgat tggcaaagtg tcattgagtt agattccttt
     1861 tttgaggata ttatggtttg tcaagacttc gatgaatttg aacaggtttt acaatccgac
     1921 tctaaaatta gtgctattga tgttgctaaa tttttcttag caatgcgtcc actctcacac
     1981 ttacaattgc aaaagttagt ttatcttgct tataaaacat atcttcttgc ctatggtgaa
     2041 tccttatttg atgaaaaaat agttgctttt caatatggtc ctgtagtaga agaggtgtat
     2101 cacagcttta aaaaatatgg ttctgaggtg atagatatcg atgatcatac agaatatatt
     2161 ttaaaagaca tacatcttcc gcaagcctta ggtagaatgc tattggtcga agacgcaaag
     2221 aagattgtgc ctgtattatt agatgttgtt aaacagtatg gagatttaac aggaggagaa
     2281 ttggttaagc tgacgcactc tgaaaaggga ccttggcaga cggtttttcg tccacagtta
     2341 aattgtgaga tcactgatga ggttatttta gcccaaggca gatatgaaag attatcatca
     2401 taagtacctt tgcttattgt attagctgag aatactcagt tgtctcatca aaaccaaaac
     2461 aaaaaagcct ttgaaacgtt gatttcaagg gctttctgta tatcgtctta ttttacctct
     2521 gtaaacacaa catgtttacg tagttttggt gagtattttt tcaattgaag gcggtctgga
     2581 gtgttacgtt tgttttttga agtaaggtac aagcgttcac cagattcttt gtgttcaagt
     2641 gtgatattta cgcgcatggt atctcccttc tattattcag ctgcgttagc tttagcgatt
     2701 ttatgtcctt tgtagtatcc cttaagtgag acacgatgtg aacgtgagta atctccagtt
     2761 gtttcgtcaa attttactga tggtgcagtc aatttgtagt gtgtacgacg tttgttcttt
     2821 ttagcttttg acgtgtgacg tgcaggaact gccatttttt ctatcctccg ttaaatgatc
     2881 aagggtctat taaaagattg gtgacaaact ggtgtgcatg atcttatgct aacctatctg
     2941 tctcaaatct ttgacccatt gttatctatt tgatgttatg gctttcgcca actttagtat
     3001 catatcatat cttctatgta aagtaaagtt acttgacaaa aattttatta aaaagctctg
     3061 ctattctcca aaaatcctaa aaaatggtaa aatgagacaa aggtggttat tttaggagat
     3121 taagatgttt ggaaaattat taagtctgtt aggctttgtc gttgctttga ctggttgtgg
     3181 tgtttcacag gcagaaaaag aacgtgttgt aacagagtat agccccatta ttattaaaaa
     3241 atttcaaacc ttaggatacc aagggaaaat cactgtagac gactatacta agatgattga
     3301 gacaggtagt gagagacttt attttaccta cagcgaagaa gtagacggta aggttattag
     3361 tctgaaggat agtatttcga ttgctaccta taaatcacct gaggaagatt tggctgatgc
     3421 agaagttgac atgggaatta gggaagaagc tatgtggcag caaccagctg tcaaagcgca
     3481 agctgctcag atcaaacaac tatttagcga gttggagact gaggatttga agcttatatc
     3541 cgtaacagga caaagtgtcc agacgatttc tgattcagat ggagagctga ttagggaaga
     3601 tgttgtacga ggcaggaatg aattatctca agatgcatct aataatagag aagctgggct
     3661 atcaataggt ggctattatc atattgatgt ttcaaagtat ttgaaaaatc acgtgttgga
     3721 aattcgtata gattttgatt ggcgaatgtc agaagaggaa caagacgatt tgtctggccc
     3781 caggttggat ttttctgata gaataaaaag tctagacttt acctgcttgt gggatggcta
     3841 ctataaagtg gggtttgaca gggtgagtag atctaatcga agtggagata ttcaagatat
     3901 gattgtttta gatattcgag gcggtaaatt ggttcgtagc ttttctgtac tttaacagat
     3961 taatgaagct attctatggt aaaatatata aatactagta aaagaggaaa taaaatgaag
     4021 cttcaaaaac caaaaggaac acaggacatt ttgcctgtgg ctgctgctaa gtggcaatat
     4081 gttgaaggtg ttgcacgtga aacctttaag caataccatt atggtgaaat ccgaacacct
     4141 atgtttgagc attatgaggt cattagccga tcagtaggtg ataccactga tattgtgacc
     4201 aaggaaatgt atgacttcta tgataagggc gaccgtcata tcacacttcg tccagaagga
     4261 acagccccag ttgttcgttc gtatgtggaa aacaagctct ttgcgccaga ggttcaaaag
     4321 cctgtcaagc tgtattatat tgggtcaatg tttcgttatg agcgtccgca ggccggccgt
     4381 ttgcgtgaat ttcaccagat tggtgtagag tgctttggct ctgccaatcc tgccactgat
     4441 gttgagacga tcgccatggc ttatcacctc tttgaaaggc ttggtattaa agaggtgacc
     4501 ttgcatttga atagccttgg aaatgcagct agtcgcgcag cctatcgtca ggccttgatt
     4561 gattacctat ctccaatgcg tgagaccttg tccaaggata gtcagcgccg tttagatgaa
     4621 aaccctctgc gcgtgcttga ttccaaggaa aaagaggata agattgcagt agcaaatgcc
     4681 ccatctattc ttgattatct tgacgaggag agtcaggctc actttgatgc tgtgcgcagc
     4741 atgcttgaag tacttgctat tccttatgtt attgatacca atatggtgcg tgggcttgat
     4801 tattacaacc acacgatttt tgaattcatt acagaggtgg atcagtctga gctgacgatt
     4861 tgtgctggtg gtcgctatga tggtcttgtg gagtattttg gtggaccagc aacccctggc
     4921 tttggttttg gacttggttt ggaacgtctt ttgcttatcc ttgataagca aggcgttgaa
     4981 ctgccagtcg aagaaggctt ggacgtttac atagctgttt taggggctta cgccaatgtg
     5041 gcggcgctag ccttgacaca ggccattcgc cgtcaggggt tcaccgtaga acgcgattac
     5101 ctcggacgta aaatcaaagc acaattcaag tcagctgatg ctttcaaggc aaaggtagtc
     5161 atcaccctag gtgaaagtga aatcaaaaca ggtcaagctg tccttaagca taatcaaact
     5221 cgtcaagaga tgacagttag ctttgatcaa atccaaacaa attttgccag catttttgca
     5281 gaatgtatcc agtaaagcaa aaaaactgaa aaaagtggta tgagtcatta agatactaaa
     5341 aaatcacaca acgtcgttgc tttaatagca atgatattgt gtgattttgt gatgttatac
     5401 ctatactaag gactattttt cctattttta gtagtcagtt tgaaagcact cttgtttgga
     5461 atggcagcag ctatgcttat agctggtgat gggttaatgc tattgttgag aaactaaaac
     5521 aatgttagag aagataatgc tgactttata gatgttattg tctatggttt gctggtatag
     5581 tccataatac tgttgaacaa ttttttgaac atttttaatt cccaatccgt cttttttccg
     5641 ttgacttctg gaggcaagct cttttggatc aaaaaagttt tcgatatcaa tgtggagttg
     5701 atttttaaag agtctcacct ttaattgtat ttgtttttca gctttatttt gattgcgaat
     5761 agttgcggca atgctattat caagtagatt tcctataatg actgaaataa cttcagtctt
     5821 taggcttatg tttgtaggga taaggcagtg aatatctaac acaatgccat tctttttggc
     5881 tacgactgct ttttgattaa gtaaataatt taaaatagta tcattggtaa agaaagtatc
     5941 tgtcccatct agcaggttaa ggttatgatt cagtaattgt tgggctttag tgtactgctt
     6001 ttgctccaga agtcctaata ggacaatgtt ttgattatgt agatcatgct taagagccct
     6061 aatgcttaat tgattttcct ttacattttc taaatgcttc agttctgact ggaatcgtac
     6121 cctatctaag ttaatgtctt gcatttgtaa atgctgatct gaaatgtaag tatacagata
     6181 cagcgaagtg attgtgataa tgataaatcc aagtgttagc agtattgtaa acaagtcaaa
     6241 taaaggttct tcttttaatc gaaggagctg tagcagtagc agagaaagac ttatcattgg
     6301 aataatagat agctttagta tccagttggt ttgtgtttgc tcatcaagcc aattgtctgt
     6361 agtctttaaa aagagctgct ttaacacaaa tataatgata atactggata tggtaagcag
     6421 gtttataaat aaaaatgtcc cactgataga agagatttga tatttaagag atattaaaat
     6481 gatccctaag cttgcttcta gcaggatacc tatgctttga agtgtaacag accaaaagat
     6541 acactgtttc atggagtaac gatagctact agatattatc agtgatgtta ccaaagaaca
     6601 agtcagggtt atcagtgagg catagcttcc tgatacaaaa aaatgagtgc agcattctat
     6661 gaatactaaa aaagagagat aacctatgtt tttaaaggta gctagctgac catttttctg
     6721 acgaaaaaaa taattaacaa tcacaatatt aacaactgat gtataaagat gaaaaatagc
     6781 gttaatagcc atttactctc cttagcttgg aaaagatgtt ctcctgaata cccttcttaa
     6841 atttccgact gataggaatg ataaaaaagc gcgtgttatc aatagctaat gttatgtcat
     6901 tgttttcaaa tttatagaag taattgacgt taaacacata agaatgatgg gtttggataa
     6961 attgttcagg aagctctttt agtaatgctt tggttgataa aaaggtagag taggtcttgt
     7021 ccttggtatg aatgagtact tttcgtcctt ccttttcaaa atagataata tcgtttaagc
     7081 ttaagctata gtaggagtgg caagatgaaa aggtaaaaaa ttttttgtca agctctaaaa
     7141 cccttagagc tctatttagg cactcaaaaa aatagggttc atttaaaggc ttaatcaggt
     7201 aatcaaaggt ttgcacgtga aaaatgtttt ccatgtattc tttgtggctt gttaaaaaga
     7261 taataatagc agagagatta tctttcctaa tatgctcggc taatgctatt ccagacatgt
     7321 tatccatttc aatgtcaaga agaaaaatat ggtaatcatt agacagtgac tgtattaatt
     7381 gacaaggatc ctcgtaaatg tctaactcca ctggaactaa ttgattatat tggtataata
     7441 gatcttctac agctgttgca aaagctttat tgtcatcaca aagagcaatt ttaagcatgg
     7501 tacccccata atcctataga ctgtggtatt tagtatacca aaaatgacat gaaaagcgct
     7561 attttttaca aaataataat aatagactga atgttttgat aaaatgaatc tatgaaatga
     7621 gggagcaata atgactgaag taacagtgcg taaaccgatg gaaacaatgg aagtttcatg
     7681 ggtagtcatt taaatactct aaagtgggct gtttttatca gcctacttta atatttttag
     7741 gagggtaaaa aatgaattat agcagacctt gtattaaaga tatttatcca atttataaac
     7801 tgagtgatac catgtttcga ataggcgctc aaattaatat tacgacggaa tttaacgatt
     7861 caaattatga aacaggtgct tcatttacac ataagctttg gccacatttc aaagagtgtc
     7921 cggcttgtgg tcatggcaac agtaatgatt gggaaatatt tagtcattat gggtaggagt
     7981 taatcaatgg aacaatatga attaatggtg aggtcacttt caaaaaggta tgccagagat
     8041 ggctcttatg ccaataggga tttacattgt gtctttaaat ccagtgaaat aacagccttg
     8101 ataggtcata atggagctgg taaaacaact ctactaaacc agattattgg taatataaaa
     8161 cctgatgtgg gtgatatttc atttctagac tgttcgtttg tcaagtcccc taaaattgct
     8221 agaaaaaata cgtcaatgat gcctcagcta catgccccct taaaaggaat cacaattaaa
     8281 caggctattt catcaattgg aaaaatcaga gggctgtccg gaaaattatt ggagacagag
     8341 gttcaggaat taattcaaga actcggtctt attaagtggc aaaatactgt cggagagaaa
     8401 ctctctggtg gactaaaaag attgacgtcg tttgcaatgg ctgttattgc tgctccgaag
     8461 attgttttac tagatgagcc gacaaatgat gttgatccta taagacgtat aaaattatgg
     8521 ttatacttaa aaaagatggc ggcaaaggga catatcgtta ttgttgtcac ccataatatt
     8581 ttagaggttg aaaaatatgc agatgcttat tatttgcttg aaaaggggga agtaaaaagt
     8641 tcaggagcgg taaaaaccct atccagcaat ccaaagagta gaatatccat tttatttaga
     8701 gatcaaaaag ccttggaaga atacccattt gcttactcac ttggtgggga tgacaatgaa
     8761 gctataacaa taatggataa taaggaaatg acagcattat tgaattggtt aggcatacat
     8821 ttgtcatcag ataccattgt tcaatatagt atcacgacgt tagggttaaa tgattattat
     8881 gaggagctgt cagatgaaga agattagtgt tacttaccaa tttctaagct tgttaaattg
     8941 gagctttatt cgccataaat cgttgatatt attgtgtagc gttattcaat tttttatgac
     9001 aattgcactg gtttacggtt attcacttat tattgctgat gatactgtgc aaacagtcta
     9061 ctatcttgct tctggctcag taacgattgg tatgattacc attggctgta cggtatcagc
     9121 acaatcaatc agtagtgata aaagagatgg cattgtgagc tatattcaaa cgttacccgt
     9181 cctaagaagt ttgatcctgc tatctgatct attgatttgg acattaactg ctttgattgg
     9241 tgttggtgtg tcaattgcgg ttgtttattt aaaatttcaa atattgcccc agctgtcctt
     9301 agcgacgttt cttattttgc cattagtttt aatgacaatg atcagtatgg gttttgccat
     9361 tgcttattgg tcaactccaa gtacgatgat gctggtaacc caattattgt tgatgattgg
     9421 cttattgttt tcacctataa tgtatcctgc agaacgtata cctgaggtga ttttaagggg
     9481 atatcatttt ctgccattta taccagcagg agacttgatt cgagagacgg tttatttggg
     9541 gcattccatt tcagttgtca agcttgtggt gttactgtta tggctggttg ccactgcctt
     9601 actttcagtc aattggctaa acaggcaaag ctaaggtata ggctctgcta tttcttaaaa
     9661 actctactca aatgggtggg gtttttaatt gttttttgtt ataataagtg gtaatgatat
     9721 ttttaattag agaaaggaac aaagacaggt agggagtgtt gactctttat ttgctcttgg
     9781 tatcttattt atgaagcgta gcatgtatgc aggacacgtc cgaaaggaac atattggaag
     9841 aacgattgtt ttaaaaggtt gggtaagtcg ccgtcgtgat ttgggcggcc ttattttcat
     9901 tgatttgcgt gatcgtgaag gagtgatgca gctggttatt aatccagagg acgtttcagg
     9961 tgatgtgatg gcgactgctg agcgcttacg cagtgaatac gtgattgagg tggaaggaag
    10021 tgttgaggcg cgtcagcagg ctaatgataa gctagctaca ggtgcagtgg agctaaaggt
    10081 ttcaggcttg accattctta atacagctaa aacgacaccg tttgaaatca aggacggtgt
    10141 tgaggttagt gacgatacgc gtttacgcta ccgttattta gatcttcgtc gtccagaaat
    10201 gctggaaagc tttaagcttc gtgccaagac gacgcatgtt atccgtaatt acttggataa
    10261 tcttggattt attgatgttg agacaccgat gttgacaaag tcaacgccag agggagcgcg
    10321 tgattacctt gtaccaagcc gtatcagcca gggacatttc tatgctttac cgcaaagccc
    10381 acaaatcaca aagcaattgt taatgaatgc gggctttgat cgatattacc agattgttaa
    10441 gtgcttccgc gacgaagatt tacgaggaga tcgtcagcct gagtttacac aggttgactt
    10501 ggaaacgtca tttttatctg agcaagaaat ccaagatatt gttgagggta tgattgcaaa
    10561 ggttatgaag gatacaaagg gcatagaggt taagctgcca tttccgcgca tggcttatga
    10621 tgacgccatg aatcattatg gctcagataa gccagataca cgctttgata tgcttttaca
    10681 agacttgaca gatcttgtca aggagattga ctttaaggta ttttctgagg cacaggctgt
    10741 taaggcaatt gttgtcaaag gacatgcgga tcgctactcg cgaaaggaca ttgataagct
    10801 gacagaattt gctaagcaat ttggtgctaa gggtctggca tggctgaagg tggttgatgg
    10861 tgcatttact ggaccaattg ctaagttctt gacaggtgtg aaaagtaagt tgacagagtc
    10921 tttacagctt gagcataatg atttggtctt gtttgttgca gacaccttag aggtagccaa
    10981 caatacccta ggtgctcttc gtacacgtat tgcaaaagag cttgacatga ttgacatgtc
    11041 tcagtttaat ttcctatggg tggttgactg gcccatgttt gaatggtctg aagaagagga
    11101 gcgttacatg tctgctcatc acccatttac attaccaaca gcagagtcag cccatgagct
    11161 agagggtgat ttagccaagg ttcgcgctgt tgcttacgat attgtcttaa atggctatga
    11221 gcttggtggc ggaagccttc gtatcaacca aaaagacatg caagagcgta tgtttagagc
    11281 actaggcttc acagctgagg aggccaatga gcaatttggc ttcttactag aggctatgga
    11341 gtatggcttc ccaccacatg gtggtcttgc tattggtctt gatcggcttg tcatgctgct
    11401 tgctggcaag gacaacattc gagaggttat tgcctttcct aaaaacaata aagcatctga
    11461 tccaatgaca caggcgccta gtctggtatc tgaaaagcaa ttagaggagc ttcagcttca
    11521 aatagaacat catgattaaa aaaacaacct ataggaaaag agtaaaatac ctgattaata
    11581 gaggagccaa aaaaattggc ttgcttcatg ccgtaaaaag catttccaag gagaagtata
    11641 cagagaaaat ttcggcctct ttactctatg gcatattgtc tagtatagct gttaatttct
    11701 ttttccaacc gggccatgtc tactcaagtg gtgcaacagg acttgctcag gttatctctg
    11761 ccatcagcca ccatttatgg ggctttgaga ttcctgttgc tttagctttt tacgtgacta
    11821 acattcctct tttagtctta gcttggtata agattggtca taaatttacg atttttacct
    11881 ttattaccgt tagtatgagc tctttcttta tccaaatcat gcctcaggtg accttgacga
    11941 ctgacccact gattaatgct atatttggtg gcttggttat gggtttgggg atcggtacag
    12001 gcttcaagtc tcgcatttct agtggtggta cggacattat cagtctgaca cttagaaaga
    12061 aaacaggaaa agatgtcggt aacctttcat tgatgatcaa tggtgtgatt atggcttttg
    12121 caggactgtt gtttggctgg cagtatgcgc tttattcgat ggtgactatt ttcgtttcta
    12181 gtcgagtgac tgatgcgatt tttaccaagc aaaagaaaat gcaggcgacc attgtgacca
    12241 gctgtcctga caaggtgatc cacatgattc ataaaaagct gcaccgaggg gtaaccagta
    12301 tcaatgatgc tgaaggcacc tacaagcatg agcataaggc tgttttaatt acgattctca
    12361 cacgtgagga atatagtgaa tttaagtggc tgatgcttaa aacagatcca aatgcttttg
    12421 tttctgttgc tgaaaatgtt agaatcattg gtcgctttgt cgaatcagat gaagactaag
    12481 aaataggtat caatatgcca gctaataaga gcttaaagct taaaaattgt tgttttatta
    12541 ttcttggctc agctatttat gcctttgcct ttgtctactt ttacatggca aatcgtattg
    12601 ctgctaatgg gctagcggga ctgacgcagg ttgctaatgc cttgtttcag atcaatcctt
    12661 caataacggg ttatctgatt aatttgcctc tcgtcctgtt gggtgcaagg ctctttggca
    12721 gacgggcaat ggtgtatact gtgaccggta ttttatcact ttattggttt gtttggctgt
    12781 ttcaacagct cccccttttt attgacttag atcatgacaa tttagtagtg tccttgctgg
    12841 caggaattct tggtggttta ggtggcggca ttgtttttag aaatggtggg acgattggtg
    12901 gctcagatat tattgctaag ctgatagagg ataggtttgg cttgcagctc aatcaagcct
    12961 tattagggat tgatattttt gtcattgtgg tttctttgac ctatatttca ataccgcaga
    13021 tgatgtatgc tttgattgct agctttatgt atagtaggat tgttcatctg gtgcaaaatg
    13081 gtggctattc tgcacgcgga acctttatta tttcagatta ttctcagact atttcacaat
    13141 tcattatgga ggagctcggt agaggagtca cctatttaca tggtgagggt gcttactctg
    13201 gtcgtgagaa acaggttatt tatgtagctc taggtcgatc agatgtacga gagctaaagg
    13261 cctttatagc acaggttgat cccaatgctt ttgtttcttt ctttgatgtt aacgaagtca
    13321 atagtccaga atttattgcc acaaaaagta aataccataa aacgaaaaaa agataaaggc
    13381 tggaatatca cattcatagc ctttgattat gctaatgaaa gcgcttggct attaagctta
    13441 ttgtagtgta gctattaaat ggccgtcctt gagctttcat ctggtaccta acaaatgtaa
    13501 tgaatagtga ggaaagtgaa tgacaaatct tgacaaatgg catcgtgtaa gagagctatt
    13561 attaattgcg gtgggtgttg ctatctatac ctttggtttt gttaatttca acatggctaa
    13621 tgaattggct gagggtggcg tagctggaat taccttgatt ttgcatgctc attttgggat
    13681 caatccggct tattcgtcac ttttatttaa tctgccttta tttatgttag gggctaagat
    13741 ttttggaagg cgctccctag ccttaacgat ttatggaacc gttcttatgt cagtctttat
    13801 ctggctgtgg caaaaggtgc ctatggagct tggtttagag aatgatatga tgcttgttgc
    13861 ggttgttgca ggcttgtttg caggaattgg tagtggcctt gtttttcgat atggagcgac
    13921 aactggtggg actgatatta ttgcccgcat tgcagaggaa aagtttggtg ctaagctggg
    13981 gcaaaccctg ttatttgtag atgccttggt attaacagcc tctctcactt atgttgattt
    14041 gaagcatatg ctctatacat tagtggctag ctttgtcttt agccagatga ttagtgttgt
    14101 tcaaaatggt ggctatacca ttcgtggtat gattattatc actaagcagt cgcaagccgc
    14161 ggcgcaggcg atcttgacag aaatcaatcg aggagtgact tatttaaagg gacaaggcgc
    14221 ttattctggt catgattata atattatgta cgtgacgctc aatccaacag aggtgcgaga
    14281 ggtgaagcgt attttagcag agctagatcc agacgccttt atctctatta ttgatgttga
    14341 tgaggtaatc agctcagact tcaagattcg tcgcaaaaat tttgacaaac caattgagaa
    14401 ggctttacag aaaaaatcca acatgttaaa ataaagaaaa taagcagaaa taagaggttg
    14461 agaaaagcca tgattaacaa ttaactcatt gtcaagcact aatctatgat taacagcaag
    14521 ggattagtgt ctgctttgag gcttgggaat cagggctttt tgtgtgcact ttttcaggcc
    14581 tttctgatga tagaaaggaa taaatatgga agcacttagt attcagcatt acgctttaga
    14641 tacagcagaa aaaaacttat tgacaataga ttctcttaca ttgaatcaag gtgagagggt
    14701 tttcatcatt ggtgataatg gggctggaaa gaccagcttt ttaaagacaa ttatcggaga
    14761 aagcactaac tatagtggct ttttgcaggt gcatggagat attgcttatg ttccgcaaat
    14821 caagtccact agccctcagt caggaggtga gagggcgatg tcttacctaa aagaggcttt
    14881 tcaagcaagg ccttctctgt taattttaga tgagccaagc tcttatttag accatgctaa
    14941 tcgtgattgg ttgattaatc aattgaaacg ctaccgagga accttgctgg tggttagcca
    15001 tgatcggtat ttgatcaatc aattgagtca gaaaatatgg ttgcttgagc atcaaacgat
    15061 caagacttac catggcaatt atgatgatta tcagcgttct agacagctag aggaggataa
    15121 gcagctaaga gcttttctgg aataccaacg aaagactaat caactgaaaa aaagcctgac
    15181 cagaaaaaaa gtgcaggcca acaaaatggc tgtaaagaaa aagtcggttt ctcggtcaga
    15241 ttggaaaacc aattcctttg cgggcagcta tgattcacag gccaaggcta tggcaaaagc
    15301 agctaaagct atggaaaatc gactcactcg aatgaaagag gttaacagtc cgcgcaaaaa
    15361 ggcttgggca aaattaaaaa aggatccaaa cgaaggtgca ctaccaaata ctcttttaca
    15421 cctacaagaa ggtaccctta caagggacca tcagttattg tttgactatc ctggtattgt
    15481 gatcagatca catagcagga tagcgattat cgggagaaac aaggctggta aaagcagctt
    15541 tttagatcag ctggcagccc aggccttgtc tggattttat gcgcaaaatc taaggataac
    15601 ctattttaaa caggaccagg ctgacttgga gccggatcag acagcagtag agctcattag
    15661 tcggcagtcc agccaagata gggtcaccat tttaaattat ctagctatga tgggcattga
    15721 ttatgataag gccaatcaaa aggtagctgt cttatctggt ggggaaaggg ttcgtttggc
    15781 gttagtggct gccttgctga cagatcatca gcttttgatt ttagatgagc cgacaattta
    15841 tttggatctt gtcgctattg aggctttgga gtcttgcttg attgactatc cagctgctct
    15901 tttgttggtt tctcatgacc tagcatttgt taacaaggta gcaacagaaa tttatgaggt
    15961 taaggatcat catttaacag cctatcattt tgaagactag caaaaaagcc taggctagct
    16021 tatcctcgct agcttaggct tattagtcta catttcattt ggtgcctcaa cacccaatag
    16081 acgaagcgct tctttgagga cgattgcagt tgcatagcaa agcgctaagc ggttgtcacg
    16141 ttctggatcg tcttcgagga tacgggtatg cgcataatat ttgttaaagc tttgtgccaa
    16201 gtgaatagca aattttgcca tgattgatgg ctcaaagtta tcaaaagcac gcttgatgat
    16261 acgtgggaag tcctggataa gcttaatgat ttcccagctt tcaggatcat taaggctata
    16321 gcttgtatcg gtagctggcg taaagcttgc tttacgcagg atagattgga tacgtgcgtg
    16381 tgcatattgg acgtaaggac cggtttctcc ttcaaaggat accattgctt caagatcgaa
    16441 gtcatagcca ttcatacggt ctgtttttaa atcatagaac ttgatagctc ccacaccaac
    16501 agcatgagct actgcttcct tgttggcaag cttaggattt ttagcttcga tttggtttgc
    16561 tgctctgctg atggcttctg caaccgttgg ctcaagcaaa atgacattac ccttacgtgt
    16621 tgataatttt gcaccgccct ttgtcacaag gccaaaagca acgtgtgtca tgtcatctga
    16681 ccaatcgtag cccatttctt taagaacagc ctttaattgc ttgaagtgtg cagcttgctc
    16741 gttgccaacc acgtaaactg attttgcaaa atcataggta cgcttgcggt aaagggcagc
    16801 agctagatca cgagtaatat aaagcgtagc tccatctgat tttttaatga gagctgggtg
    16861 ctcaatacca tatttttcaa ggttaaccac cttagctccc ttagattcga ctagtaggcc
    16921 tttgtcctca agaagctcaa ggacctcatc cattttatca ttgtagaagg cttcaccatt
    16981 atagctatca aagctaactc ctagctggtc atagagtcgg ttaaactcaa tcaagctttc
    17041 atcgcggaac cactgccaaa gctctgtagc ctcttgatct ctctcctcta gcctgcggaa
    17101 ccattcacgt gcctcctcat caagactagg atcagtttct gcctctgcat tgattctcac
    17161 atagagcttt aagagctcat caattgggtg tgcttgaaca gcggcctcat ttccccactt
    17221 cttatacgct acaatgagca taccgaattg cttgccccag tcacctaggt gattgatttt
    17281 aacaggctta tagcccattt ttgcaaagat atgagcaaga ctgtccccga taactgttga
    17341 gcgcaggtga ccgattgaaa atggcttagc aatgttaggg ctggacatat caatagcaat
    17401 atgacgtcct tgtccttcat cctgttgagc atagtcagct ccgtcagcaa tcacctgtgt
    17461 aagaacctgt gcagaaatgc tagccttatc taaaaagaaa ttgacataag gaccaacagc
    17521 agcaaccttc tcaaattggc tggcgtcaat cctttcagct aaatcactag caatagcttg
    17581 tggtgctttg cgaagcgcct ttgctagact aaaggctgga aaggctaagt ctcccatgtc
    17641 agaatttttg ggtgtttcaa gtaagttaaa aatggcagcc tgctctagtt caggaacaat
    17701 cttagcaatc tcagctgcaa tcagagtttt agtgtccata ttgcttctcc taaaaatagt
    17761 ttgtcaccct attctaacac atttcttgga aataaacgag gtgtctattg agaaattata
    17821 ctagaaggct tgtaggtgtt ttggggaaca aagctaaaga attagagcag caaagcttgc
    17881 caaatctaag ggtctaatga tatgagcaag aaataatgct tccttaaaat aaagcaaatt
    17941 gacagagctg agatgaaata ctaccatttt tttgttataa tttgagagga taattataca
    18001 ttggggagat atatcatgaa taaaatagaa cggcagcagc aaatcaagca acttattcag
    18061 gctgagcaca tcggtacaca ggaggagatt agacggcttc ttcaaaagga tggtatcgtg
    18121 gtcactcagg ctaccctatc acgagattta agagaaatcg gattacttaa attaagagat
    18181 gacagaggta agctatacta tagtctttct gagcctgttg ccacaccatt tagtccagat
    18241 gtgcgctttt atgtcctaaa ggttgaccgg gcgggcttta tgctggttct ccataccaat
    18301 ctgggagaag cagacgtgtt ggcaaatctt attgacaatg atgccattga ggacgttttg
    18361 ggcacgattg cgggtgctga taccttactt gttatttgtc gtgatgagga gattgccaag
    18421 cgctttgaaa aagatttagc tgctggtcta taatatgcct taccgcgaat ccttacatca
    18481 gctgatagca gcactggaaa agcactcaag cattatagct tataaggagg ctcagcagca
    18541 cttgcttcaa aggactgatt ataatcaaaa ggcctatcag atgaagcgac atcaacagga
    18601 cacctatctt tttcgtcaaa tcgctaagga taaagcagct gaagaatcag cttttaaggc
    18661 tcagcaatta cgagaagatt tagatcatca accattgata gatgattatc gtgacaaaat
    18721 gcaaaacgct agtgacttgg ttcggtacat tacagggact atagaagatg aattaaataa
    18781 ggagttcaat gatggcaaag gctaatgttt ctcccggaat gcagcagtat ctggacatca
    18841 aaaaggatta tccagatgct tttttgcttt ttaggatggg agatttttat gagttatttt
    18901 atgaagacgc tgttaaggca gcgcagattt tagaaatcgg cttaaccagt cgtaataaaa
    18961 atgctgacaa cccaattcca atggcaggtg ttccctatca ttctgtccaa caatacatcg
    19021 atgttttaat tgatttgggg cataaggttg ctattgctga gcagatggag gatcctaagc
    19081 aagcggtcgg tgttgttaag cgtgaggtgg ttcaggtcat taccccaggg acagctgtgg
    19141 actcaagcag acctgatagt cccaataatt ttttggtggc tgttgatttt gatggcaagg
    19201 cttatggcct gtcttatatg gacgtctcta caggagaatt ttttgctaca gacctagcag
    19261 attttgccag tgtcaaaagt gagattcaaa acctgaaggc aaaagaggtt cttttaggct
    19321 ttgaattatc tgaagaagag caggctattt tagtaaagca gctgaatctt ttgctgtcct
    19381 ttgagatgac agcactagag gattcgcctt tgattgatca tcagctaaca gcagtcgagc
    19441 tgtctgcagc aggtaagctg ctacactatg ttcatcaaac ccagctgcgt gagcttagcc
    19501 atctacaggc cttggtgcac tatgatatta aggattattt gcagatgtct tatgcaacca
    19561 aatcaagcct tgacctgctt gaaaatgctc gtactggtaa aaagcatggg agcctttatt
    19621 ggttgcttga tgaaaccaaa acagccatgg gtatgcgtct attaagggct tggattgata
    19681 ggccacttgt gactagtgag gcgatcctag aacgtcagga aattatccag gtgtttctta
    19741 atgcttttat cgaaaggaca gatctaagcg atagtttaaa gggtgtttac gacattgagc
    19801 gcttgtctag tcgtgtatct tttggaaaag caaaccccaa ggatctatta cagctaggtc
    19861 atactttggc caaagttcct tatatcaagg ctatcttaga ggcctttaac agtccttacc
    19921 ttgacaagct tgtcaaccaa attgacactt tgcctgagct agagcacctg atacggtcag
    19981 ctatagatcc agatgctcct gctactatca atgaaggcaa tattatcaga acaggctttg
    20041 atgaacggct ggatcattac cgaaaggtca tgcgagaagg caccggctgg attgctgata
    20101 ttgagacaaa agaaagacag gccagtggga taagcaatct caaaatcgac tataacaaaa
    20161 aagatggcta ctattttcat gtgaccaact ctaatctagg tatggttcct gaccattttt
    20221 ttagaaaggc aacattgaaa aattctgagc gctatgggac agcagagcta gctaagattg
    20281 aaggacaaat gcttgaggct agagaggagt catctagcct ggaatatgat attttcatgc
    20341 gtattcgtgc tcaagtggag acctacatcg ataggctgca gcagctagca aaagctctag
    20401 caactgttga tgtcctacaa agcttagcag tggtcgcaga gaagaatcac tatgttcgac
    20461 cattatttaa tcaagagagc aagattgcga ttgacaatgg tcggcatgct gttgttgaaa
    20521 aggttctagg tgttcaggag tatattccaa acagcatttc ctttggtcca cagacaagca
    20581 ttcagctcat tacaggacca aacatgagtg ggaagtctac gtatatgaga cagcttgctt
    20641 tgacagtcat tatggctcag ataggctcat ttgtagctgc agaatctgct agcctgcctt
    20701 tatttgacgc tatttttact aggattggtg cagcagatga tttgatctca ggccagtcta
    20761 cattcatggt tgagatgatg gaggctaatc atgctatcaa gcgagcaacc cctcattccc
    20821 tgattttgtt tgatgagtta gggcgtggta cagcgaccta tgatggtatg gcactagccc
    20881 agtctatcat cgaatacatt catgatagag ttggtgcaaa gactatgttt gcgacccatt
    20941 atcatgaatt gacagagctg tcaaccaagt tgacaaagct ggttaatgtt catgttgcga
    21001 cgttagaaaa agatggaaat gtaaccttcc tgcataagat tgccgaaggt cctgctgata
    21061 aatcctatgg gattcatgtg gcgagaatag ctggattgcc agaggattta ctagccagag
    21121 ctgatactgt gctaaccaag ctggaagctc aatcacaagc aagagagtcc gtcttatcaa
    21181 ctacagaagt aagagagact cagcagctgg ctaatcagca gctatcactt tttacagatg
    21241 atggctcctc tagcgagatt attaaaaggc ttgagagtgt tgatgtgatg aatctaactc
    21301 ccattcaggc catgaccgtt ctttatgagc taaaaaagct actgtaaaag ctagtatcag
    21361 atgttaaagg cacttgtagg ctcaccaggc cacaggtgct ttttggttta ttgaccataa
    21421 gacccttgct agctctgatg cttggctctt ttagttttat gttataatag tccataagaa
    21481 tgcgaggaaa tatatgacaa caattatcga attacctgag gttctcgcca atcaaattgc
    21541 agctggtgaa gtcattgaaa gaccagcaag tgttgttaaa gaattggttg agaacgccat
    21601 agatgcaaag agtagtcaga ttactgttga aatagaagag tctggcttga aaatgattca
    21661 aatcactgac aatggcgaag ggatgtctca cgaggacctg cccctgagcc tgcgtcgtca
    21721 tgccacaagt aaaatcaaaa gtcaaagtga tttgttcaga atcagaacac ttggctttcg
    21781 aggagaagct ttgccttcgg ttgcctctat cagtaaacta acgatcaaaa cagcaacagc
    21841 tgatgcagag catgggtcaa tattagttgc tagtggcggt aagattgagc agctggaagc
    21901 tgtctcaaca cctgttggta caaaaatcaa ggtagaaaac ctattttaca atacaccagc
    21961 tagactgaaa tacatgaaga gcttacaagc ggagctggct catgttgttg atgtcgtcaa
    22021 tcgcttgagc ctggctcacc cagagattgc ttttacattg atcagtgatg gcaagcagct
    22081 aacacaaacc tctggggctg gggatttacg tcaagcgctt gctggtatct atggcctgaa
    22141 tactgctaaa aaaatgattg acatttctag tgctgattta gattttgaag tgggaggctt
    22201 tgtgagtctg ccagagctga caagagctaa tcgtaattac attactatcc tgatcaatgg
    22261 tcgctatatt aaaaatttct tgttaaatcg agccatttta gatggttatg gctctaagct
    22321 gatggtggga cgctttccta tagctgtcat tgatattcaa attgatcctt atctggcaga
    22381 tgttaatgtt cacccaacca agcaggaaat tagaatttct aaggagcgtg aattaatggc
    22441 tctgattagt acagctattt cagagagcct acgagaacaa gacttgattc ctgatgcctt
    22501 ggaaaattta gctaggtcca gcacacgttc attttcaaag cctgagcaga ccagtttgcc
    22561 tttacagcct agtcagcttt attatgatcc gcaaaaaaat gatttcttta ccaaagaaac
    22621 agtggtttca gaggatagcc cgcagggctt taaccatgaa actttggttg acagtggtgt
    22681 caagcaggtt gacaatttgc agctggccaa gactgaatct gaagcagctg ctccaagtgt
    22741 taaatatgct agtcggccag atcctatgct ttctgatggt gagcacccgg gtcttgatgt
    22801 ccacaataag caaaaattat ctcagatgct tgatcgttta gaaaatgaag agcagtcggt
    22861 ctttccagag cttgattatt ttggccaaat gcatgggacc tacctttttg cccaaggcag
    22921 agatggcttg tttatcattg atcagcacgc agctcaggag cgcgtcaagt atgagtatta
    22981 tcgtgacaag attggtgagg ttgacaatag cctacaacaa ttgctggtgc cttatctgtt
    23041 tgagttttcc ggatcagatt ttattaatct tcaggaaaaa atgtcgcttt tgaacgaggt
    23101 tggtatttat ttagagcctt atggcaatca tacctttatc cttagggagc accctatttg
    23161 gatgaaggag gcagagattg aatctggtgt ttatgaaatg tgtgacatgc tgctgttgac
    23221 aaatgaagta tccatcaaaa cttatcgtgc tgagctagcg attatgatga gctgtaaacg
    23281 ttccatcaag gcaaaccata gcttagatga ttattcagca agacagctgc ttttacagct
    23341 tgctcaatgt aaaaacccct ataactgccc acatggtaga cctgttttga ttaacttcag
    23401 caaggcggac atggaaaaaa tgttccgtcg tatccaagaa aatcacacca gcttgagaga
    23461 attgggcaaa tactagagag gatagcatgc gagaattttt ccagttacct aagcaaatac
    23521 aaattcggca atttgtgcgc tttattacca ttacgcttgg cagtagtatc tttcctttta
    23581 tggcgatgta ctatacaagc tactttggcg ccttttggac aggcatacta atgatggtga
    23641 ctagctttac aggctttatt gggaccttat atggaggtca tttgtcagat gctattggtc
    23701 gtaagaaggt aattatgctt ggttcagttg cgagcacctt aggctggctg ctgaccattt
    23761 tggccaatgt tccaaagacg gttcttcctt ggttgacctt tgtgggaatt ttgctggttg
    23821 agcttgcttc cagcttttac gctcctgcct atgaggctat gctgattgat ttaacagatg
    23881 atagcaatcg tcgctttgtt tataccatta attactggtt tattaatata gccattatgc
    23941 ttggtgcagg tatttcagga cttttttatg atcggtattt cttagaactg ttgattgctt
    24001 tactgattat taatatcgtc tgctttggta ttgcctatcg ttattttggt gaaacgaggc
    24061 ctgagcatta ccgctttgag catggtattg gtattctagc aggttttgct aactaccggc
    24121 aagtctttaa ggatcgcgct tttgtgttat ttactatagg gacgatttta tttagcagta
    24181 tttggttgca gatggacaat tacgttccgg ttcaccttaa gctgtatttt gaagagactg
    24241 atgtgctcgg tattcatctg actagctcaa aaatgctgtc actgatggtc tttaccaata
    24301 ccttgctgat tgtgctgttg atgacagtta ttaatcgctt gacagcaagg tggagattat
    24361 taccacagct ggtgatcgga tcggttattt ttgcctttgg tatgctgttg tcatttacat
    24421 ttactggctt ttttgctatt tggtgttcag ttgtggtgtt taccattggt gaaatgctaa
    24481 atgtccctgc caatcaagtg ttaagagcag aaatgatgga tcagtctaaa attggctcct
    24541 acacaggctt tgtctcgatg gcccagcctt tgggagctat tctagcaggt ttgctggttt
    24601 ctcttagtca ttttacagga caggctggtg ttcagctagc atttgttttg attgcctgtg
    24661 tggggcttta tgtgattgtt ttatctgcga aaatgaagaa aaaggtgtag tatgtacgat
    24721 tatattaaag gtcagctaac aaaaattact gcaaagtata ttgtggtaga agcaaatggt
    24781 ttaggctata tgataactgt tgccaatcct tatagcttta cagactgtgt caaccagcag
    24841 gtaacgatct atcttcatca ggtgatcaga gaagatgctc agctgctgtt tggttttcac
    24901 agtgaggaag aaaaggacgt ttttttgaag ctgatttcgg tatcaggtat cggaccgacg
    24961 actgccctag ctattgtagc tgtagatgat aatagaggac tcgtcaatgc cattgataat
    25021 agtgatatta catatttgat gaggttccct aaaatcggaa aaaaaacagc tcagcaaatg
    25081 gtgcttgatt tagcaggtaa gttcgttgaa gcacctaagg aggaaagcag caagccccct
    25141 aaagccaagc aacaggggaa tgaacagctt gatgaggctg tcgaagccct attagccctt
    25201 ggatataagg cgacagagct aaagaaaatt cgagccttct ttgagggaac aagtgagaca
    25261 gctgagcagt atatcaaatc agctctgaaa atgctaatga aaggctagga gcttcatatg
    25321 aaacgttgcg catgggtacc acaagataat aagctttatt gtgattacca tgacttggag
    25381 tggggaaggc ctgtctatga tgatcgcgct ctttttgagc tgctttgtct tgaaagctat
    25441 cagtcaggct tatcttggtt aactgttttg aaaaaacgtc cagccttcag aagtgttttt
    25501 catcattatg atatctcagc tgtggcaagc tttagtgagc aggaaatggc tgctgccctg
    25561 caaaatgcag caattatccg acacaagcca aagctaatag ccactgtcaa caatgcagcg
    25621 gcagtccagc gcatccaaca agagtatggt agcttttcca gctatctttg gaactttgta
    25681 ggaggtcagc caattgacag gcttgtcaac gatgacaacc cagcgcccgc tcaaacagcc
    25741 ctatctctca agctatctaa ggacttgaaa aaacgtggct ttaagtggct aggaccaaca
    25801 actgtttatt cctttatgca ggcagcagga ttggtcaatg accatgaaga gaactgtgag
    25861 tttaggtaga attaatcgcc tctttggagt gatgtttcat gagcctatca aagagagctt
    25921 gataaaaaca gcccaatctt gattgcttat aggatgatgt ataagagcta tgtttttgct
    25981 ccgtacttta aggatagatg atgaatcccc ttatttaccc tgtagcgaat gttgtaagct
    26041 tctaatgggt ttaaggtttt agcctgttac tgctattgcc agtaagctac agtttgatca
    26101 ggtagttata ttggattgcc tcaacgattg tgttgctgct ggctggtgct tctttctata
    26161 acttattttg gtgcatgtga ttgtggctct aaaagttata acagagtatc ggtacgattg
    26221 gtgttacccc ttggtttcta tttttttctt atcagccagt ctggcattta cagcctataa
    26281 taaaagctac cgcttaaaaa tttcttagcg gtagtttttt agttcatgtt gcaaggtttc
    26341 tagaagttca gtttcttctg tcaactgtag taattgtaag cctttattaa ttaggtgatc
    26401 atcattacga caaataccga gacgaacttg ggaaaaacct aagctatcat agcgtttaag
    26461 ctgtctagct aatttgattg ttagtaaggt aatttcttcg cactcctttt tgaggttgtg
    26521 atagaggtaa atggttgaaa gattggttag taaagcatat tcagatgatt tgatattgcg
    26581 gtaatcttta tattttgcta ggctatctag gattttttga ctgatgtttt caattatttc
    26641 gataggaaag tgaaaaagaa tggtatgtag taattgtaaa tctttctcat accaagtatc
    26701 ttgttttacg agggaattcc agattttata agctagctct tgtaaatctt gattgttttt
    26761 aacgcctttt ttcctaagac ttatcatgac ttcgacacta tctaaaatat aagaaatggg
    26821 aatatcattt ttatttttaa ggtaattgaa gcatttttga cgtaattttt ctaattcagt
    26881 aatatttaca gctgatacct gattataaaa ttggtttaaa atgtcctgcc ttgtgctagg
    26941 atgataagtg ttgcagacat atctaaactc ttccagtgtc atattgagtt ggtttaataa
    27001 aaaaatcatt gtatcaaatt taggaatgac ttgtccgctt tcaatacgag ctagtgtaga
    27061 acgagctaaa aagtctccac agatcttttc ttgtgttaat cctttagatt ttcgtatagc
    27121 ttgataaatt ttaccgtaat cccaacgcat aaaacacctc taaaatgtta ctaaatgcta
    27181 caaaaaaata aaatctacaa tagtatttta taatagcatt tagaaagagt aaaggaggaa
    27241 aatttatgag gagacatcta aaggttgtat tattacttgc agcactattg gcatttattg
    27301 taaatgaggg taattttcca tggtggcctt ggggaccata gtacttaact gattactgtt
    27361 atgttgttgc cattagacta tctagattaa tcaaagagta aaatacaagt agcttagtga
    27421 aagacatttt aagaggagaa aagcatatga agaaacgttt agcatttata ttagttgctt
    27481 ttggtatttt gggatttagt ttaggaaatg aagttttagc tgcagatact gcacctgcaa
    27541 gtgcaactat ggcaacagat agtgatgtga gtttttacaa tggagaactg ttgaaaaaat
    27601 atttggtcca aagtggtgat agattgtatt ttgattatga caaagctatt caagataaag
    27661 tttctgatgg tgtaatagat atgggattcc ttgttgagac aattagtgag gactattcac
    27721 aacaaacgtt tacctctcga aagtatttca aggcaggatg gcagctttat ggtaattatt
    27781 gtggacctgg ccataacgga aatcatttta ctttacctgt tattgatgtt ttagatcaag
    27841 gctgtcaaaa tcatgacagt tgttatcgat ggggagctgg gattggtgca aattgtgaat
    27901 gcaatcgtca gttagtaaat tacattaaag tatatcgacg gtggatgcca gctcatgcct
    27961 tgggggttgc tgatgctatt agagtatatt ttgaaacggt aggtgctatt ggatgttaac
    28021 cttaaaaaat attatcaatc gatactacat gtattatgta ttccttattg ttgtgatctg
    28081 gattgggatg ttttttgtac gatgggatac tactgtggct ggtgtattac tctatccact
    28141 gattatgaag caggtattta tcgtactagg agtagttgcg atgataatgg ccattatttc
    28201 tagaaaaatt gttcttggaa tttttggttt actatgctgt gctgcttttt ggattaatct
    28261 tttcttagct ttctatctat tacctggact tttgggaaat tagcgattaa actgtttttg
    28321 atgttttgaa gatgagaaac agattgtttt tctgtaaggc ttcctgttac ttctcaaatg
    28381 ctttggagta tctctttatc atttgttcac tgttgacaac gttaaaaaga ttattccaaa
    28441 catgggaatt gctgcttcag ggtattcctt gttaatattg gattgattag ttgttattta
    28501 tgcaaaatcc ttagagcatt gctttctcat tcttggttca tttgaataaa atgtaactaa
    28561 aaaaactttg taatcaattc aaattgtcac aagtataaaa gtaaaaaagc gactttgtta
    28621 gtgatctgat attcggaagt cctatcattg ctcgcttttt gttttttgag gttgattttt
    28681 attccgaaat tgttgtgaat aagtgcaatt ttaagctaag aattacctaa aatcttttga
    28741 agattactgc ttagcttcta atacctattt atcggtgtgt tgataattgg agagatagcg
    28801 ggattgtcat atgaaataaa ttttagaaaa tttaaacaag ttattctgat tattattatt
    28861 tcaacataag tctttatttg attatcattg aaaaccatta attcatctaa aattatttca
    28921 atgcttcatg gatgattctt tttttgttaa aatgagattg aatgtcgaat agataagtag
    28981 gtgggaaaat gaaagctgaa ctcattgcgg tgggaaccga gattctgact ggtcagattg
    29041 tgaataccaa tgctcaattt ttatcagaaa aaatggcgga gcttggtatt gatgtttatt
    29101 ttcaaacagc tgtaggagat aatgaagagc gtttgctttc tgttattgat attgctagcc
    29161 agcgaagtga tttagtgatt ttatgtggtg gtcttggtcc aacagatgat gatctaacga
    29221 agcagacctt agctaagtat ctgggaaaag ctttggtctt tgatgagcag gcaggtcaaa
    29281 aattagatgc tttttttgca catcgtaagc aggctgctag gacaccaaat aaccaacgtc
    29341 aggcgcagct gattgaaggc tctattgctt tgcaaaatca aacaggactt gcagtaggtg
    29401 ggttaataac tgtagatagg gtaacctatg ttgtcttacc agggcctcca agtgagctaa
    29461 agcctatggt aaaaaatgag ctggtgcccc ttctttcagc tagtcatgcc agtctatatt
    29521 caagagtgct gcgttttttt ggcattggtg aaagtcaact ggtgactgct ctggaggatt
    29581 tgattaagca tcaaacagat cctactattg ctccttatgc aaagaccggc gaggtaacac
    29641 tgcgactatc cacaaaggct gacaaccaag cattagctga tgaaaggctg aatcgactag
    29701 aggcgcagct cttatccata agaactgtag ataatcaacc cttacggcgt ttgctttatg
    29761 gctatgggga ggataattcc ttggcgcgtg agacctttga gctattgaag cgaagtggta
    29821 agacgataac agcagctgaa agcttaacag caggactgtt tcaagctcag ttaactgatt
    29881 ttgcgggagc ttcacaggtg tttaacggtg gctttatcac ctacagcatt gaagaaaaag
    29941 caagaatgct tggcattcca ttgggtgagc tacaaaggca tggtgttgtg agctctttta
    30001 cagctgagca aatggctgca caggcacgct gcttgaccaa ttcagatatc ggtattggtc
    30061 taacaggtgt tgctggtcca gaggcactcg agggacagcc agcaggaaca gttttcattg
    30121 gccttgccac taagaataag gtagaatctc ttaaagttgt tataggaggc cgtagccgtt
    30181 tggacgtgcg gtatattgct gccctatatg cttttaatat ggttcgtaaa actttattaa
    30241 aatcagagaa tttgctataa ttaggatagt gtattttagg aaattagtaa ctagacagat
    30301 gtgaggttat gctgtttatt gcttgctagt cagcctaaat agaggagaaa atattggcaa
    30361 aaaaagttaa aaaaaatgaa gaaatcacca aaaaatttgg tgatgaacgt cgtaaagcac
    30421 ttgatgatgc gttaaagaac atcgaaaaag attttggtaa gggtgcggtt atgcgccttg
    30481 gtgagcgtgc agagcaaaag gttcaggtga tgagttcagg cagtcttgct ttagacattg
    30541 cgcttggagc aggtggctat cctaaagggc gtattattga aatctatgga ccagagtctt
    30601 ctggtaaaac aacagttgcc ctgcatgcag tagcgcaggc tcaaaaagaa ggtggtattg
    30661 cagccttcat tgatgcggag catgccttgg accctgctta tgctgcggcg ctgggtgtta
    30721 atattgatga gctgcttttg tcacagccgg attctggtga gcaaggactt gagatagcag
    30781 gtaaactgat tgattctggt gctgttgatt tggttgttgt cgactctgtt gcagctctag
    30841 tgcctcgtgc tgagattgat ggtgatattg gtgataacca tgttggcttg caggctcgta
    30901 tgatgagtca ggcgatgcgt aagctttcag cctcaatcaa taaaaccaag acaattgcga
    30961 tctttattaa ccagctgcgt gaaaaggtag gggttatgtt tggtaatcca gagacgacac
    31021 caggtggtcg tgctttgaaa ttctatgcct ctgtccgtct ggatgttcgt ggaacaacac
    31081 aaataaaagg aactggagat caaaaagaca gtagtattgg taaggaaacc aagattaagg
    31141 ttgttaagaa taaggttgct ccgccattta aggtggctga ggttgaaatc atgtatggag
    31201 aaggcatctc acgtacaggt gagctgatta aaattgcttc agatttagac attattcaaa
    31261 aggctggtgc ttggttctct tataacggtg aaaaaattgg tcagggctct gaaaatgcca
    31321 agagatattt ggctgatcac ccagagctgt ttgatgagat tgaccataag gtgcgtgtta
    31381 aatttggctt gcttgaagat actgaggaaa gtgcagctgc agatacagtt gcagccaaag
    31441 cagatgagtt ggttttagag ctagacgatg ccattgaaat tgaggattag tgcttagtat
    31501 tagattttca gataaaggtg ctaaaaaggg cttaacagcg atcgtcaagc cctttttagc
    31561 ttgtgtttaa tcaagctctg tattggtctg ctcaggagct aggctgtacg cttggataat
    31621 ttgttagctg agtttatgtt ttctttaggg attaactgtt aagctataaa agccctagaa
    31681 aaaagggact tcctacagac aagatagtgg catagtaagc ttgcttgcaa ctagctcaat
    31741 ataggatttt ggccttggtt aaagggatca taaaagaaaa ctaaaaaata ggtccaaaga
    31801 ccgatattga ttagaaaaaa actatgctac aatagaggta tcacgagata gaaagtgaga
    31861 acaacatgat aaaaatttac acgatttcaa gttgtacgag ctgtaaaaag gctaaaacct
    31921 ggctgaatgc ccataagctc ccatataaag aacagaattt aggaaaagaa cctctttcaa
    31981 gagaagaaat tttagctatt ttatcaaaga ctgaaaacgg tgtggagagt attgtctctt
    32041 ctaaaaatcg ttatgccaaa gccttaaatt gtgatattga cgagttaagc gtaaatgagg
    32101 ttattgattt gattcaggat aatccccgta ttttaaaaag tccgattctt atcgatgaca
    32161 agcgtcttca ggtgggctac aaggaagacg atattcgtgc ctttttacct cgttctattc
    32221 gtaatattga aaatgcagag gcgcgtttac gcgctgcctt ataaaaagct ctgtcagagc
    32281 tttttttaat atcctaacaa atctgaattc ttgtttattc aataaaaata agctataata
    32341 gagcgtagca cttaaagtta gaaagaaggt gtaagtatgg gatttacaga tgaaacagtc
    32401 cgctttaatt tagacgatgg tgataaaaag cagattagcg aaacgctgac ggcagtttat
    32461 cattcactag atgaaaaagg ctacaatccg attaatcaaa ttgtaggtta tgtactaagc
    32521 ggggacccag cttatgttcc tcgttacaat gatgctcgca accaaattcg taaatatgag
    32581 cgcgatgaga tcgtagaaga gcttgttcgc tattatttgc aaggaaatgg aatagatatt
    32641 agatgagaat aatgggactt gatgtcggtt ctaagaccgt cggtgtggca attagtgatc
    32701 cacttggttt tactgcccaa ggactagaga ttattaggat caatgaagat aaacaggatt
    32761 ttggctttga tagattagct gagcttgtta agcaatatca ggttgatcga tttgtcattg
    32821 gcttgccaaa gaatatgaat aacactagtg gcccacgtgt tgaagcaagt aaggcttatg
    32881 gagataagat tgaggagctc tttcacattc cggtttctta tcaagatgag cgcttgacaa
    32941 ctgttgaggc agagcgtatg ttgattgagc aggcagacat cagtcgtggt aaacgtaaaa
    33001 aagtaatcga taagctggct gcgcagctga ttttacagaa ttatttagat tgtaactatt
    33061 aaggagaaca gatgacacat aatcatgatc acgaacacga agtcattaca cttgtcgatg
    33121 agcaaggaaa tgaagcattg tttgaaattt tattaaccat cgatggacgt gaagaattcg
    33181 gtaaaaacta tgttttacta gttcctgctg gttcgcaaga ggatgaatca ggagaggttg
    33241 agattcaggc ctattcattt acagaaaatg aagacggaac agagggtgat ttacagccaa
    33301 ttccagagga ttcagacgct gagtgggata tgattgagga agtctttaat agcttcttag
    33361 acgaagagta acaacctgag gcattagctt taaaataata aatagcctag aatcttggtg
    33421 ctagcagcat gggttttagg ctatttttat ggtttatcag acagtaggag tgatagctat
    33481 ttctatgacc tctaaatagc ctactgttaa gagtgttttt agggtcttgt agatgttgca
    33541 atagcctgta atttcgttga agttacttgc tgttgtcttt tttagtttaa gccttaacaa
    33601 agcttatagg aaatgactca acttagcaca gcataagccg cttattttga taagtaaaga
    33661 aatagccaat agctactttt agcttaaagc tgatcattac cagtaccctt agcttttctg
    33721 ggtattattt cgaataatct taatgggggt gattttatca aaagactcag tcaagaagaa
    33781 aaaagctttc taaagcatta taggctaaag acactgcacc gctttaaaga gctgctgact
    33841 tatgccagca tttgtcataa attgactaaa taatagattt tgctatactt gtaatatgac
    33901 atgtcaagga gaaacacatt gagtcaatta catcaagaag ttatgctgga aaaggtcaat
    33961 tatttggtga aagaccaccc atcgtcacat acgactaagt atgacatgaa ggtccctagt
    34021 ttatataaat tttatatctt tttctttagc atcatagcga gcttgcttac ggttgcggtt
    34081 cctttttttg cagatactgc aaatagcgtt cagtcacaaa atttatacat cggaatgatg
    34141 ttgactaaag gtcagattcc atatagtgac ttgtttacaa caggaggctt tctgtttttt
    34201 gtgctcatag ctttgagcta tcacttggga acaacggtat ggttggtact tgttcaagcg
    34261 ctgtgctttt atttgacagg tgtttatttc tataaattaa tccattatgt gacaggtatt
    34321 cagaaggtgg ctttaggttt tacagctatc tattacctat tgtctattag tcttggattt
    34381 ggtggcttat atgcgatcca gcttgccctg ccttttgtct tggtatcgct ttggttttta
    34441 accaagtatt ttgctggctt ggtaaaggac gaggccttta ttctctttgg ctttgcagcg
    34501 gcaatagcca tgctaattga gcctaggacg cttctttttt ggctgcttgc ctgcattgcg
    34561 attattgctt ataatgtgtc tcaaaagcat ttcgctcgag gcttttatca gctgttagca
    34621 gctatttttg gaatgctttt ggtgttttat acagcaggct attttatcct caatttacag
    34681 attttgagtc cttatttgga gcaggcgctt gtttatccgt ttagttattt tgtgacaggt
    34741 gatttatcgc tgattctcgg tttaacagtc caattaggac ttgttcttgg cttgggactg
    34801 ttaacggggc tgctgacgtt tatgaagcag cctaagctag agtctgatct tgctatgaaa
    34861 tggctactag tctttgttgt gtttagctat gctggtattg cggctatatc gcatgatttt
    34921 catacttatc acctactgcc tttactgcct tatgctttga tcttgctatc aagctctgtt
    34981 ggccgacaat atgaggcagg acttaggatg gttagtcatc gtcgtcgtaa ggggaaaaat
    35041 ggtgcgagac gggttattgc tatttatcta aataagcatt tctacgtgcc agcaatcata
    35101 atgctaggag cggtttttgg cacagcttat cagtatgtga ccagctctgc tattaatcaa
    35161 gagcgttctc agattgctca ctatctaaga cagaggctaa cggaggacca acccatctat
    35221 gtatgggacg atacgtcaaa aatttacctg gaaacgcagg ccaagtcagc ttcacagttt
    35281 gcctcaccct ttgttaatct gaaaaaagag agtcatcaac agatgttaga ggatgagcta
    35341 ctacagaata aggcagtcta tattgtggtc aacaagcaaa aagcattacc aaaggcagtc
    35401 aagaaaatag tgacagctaa ttataaaatt gacagaaaga ttgatgttaa gggctttagc
    35461 ctatatcaga aaaaataaat aaaatcaata tattgtgttg gtataaaaaa acttaacaca
    35521 atatattgat ttttttgtgt ggcgtgatat aatagtcgag taaggagata ggacatgata
    35581 acattagaaa aagacaaagt tattgttcag ccagctatta aggttattaa aagagatgga
    35641 cgcttggtta attttgatgc aacaaagatc tacagtgcgc tgttaaaagc aagcatgaag
    35701 gtaacacgca tgtcaccgct cgttgaagca aagctagaag ctatttctga acgcgttatt
    35761 gcagaaatta tcgagcgatt tcctacaaat attaaaattt atgaaattca aaatattgtt
    35821 gagcatgagc tattagccgc taatgaatat gctattgcta aggaatacat caattataga
    35881 acccagcgtg actttgcccg ctcgcaggcg acagatatta atttttctat tgataagctc
    35941 attcacaagg atcagacagt agtcaatgag aatgccaata aggatagtga tgttttcaat
    36001 acccagcgcg atttgacagc tgggattgtt ggtaagtcta tcggtttgaa gctgctgcca
    36061 gcgcatgttg ctaatgccca ccaaaaaggt gatattcact accatgattt agattatagt
    36121 ccttatacgc caatgacaaa ctgttgtttg attgatttta agggaatgct ggcaaatggc
    36181 tttaaaattg ggaacgctga ggttgaaagt cctaagtcta ttcaaacagc aacagctcaa
    36241 atttcacaaa tcattgctaa tgtggcctcc agtcagtacg gtggctgtac agccgatcgt
    36301 attgatgagt ttttggcacc atatgctgag ctaaatttca aaaagcatat ggctgacgct
    36361 gaaaaatggg ttattgagga gctgcgggaa agttacgcct ttgaaaaaac aaaaaaagac
    36421 atttatgatg ccatgcagtc tctagagtat gagatcaaca cgttatttac ctcaaacggt
    36481 cagaccccct ttacctcatt gggatttggt ctagggacct cttggtttga gcgtgagatt
    36541 caaaaggcta ttttaacgat tagaattaat ggcttaggca gcgagcaccg tacggcaatc
    36601 ttccctaagc tcatctttac ggtcaagcgt gggctcaatt tagagccaga ctcaccaaac
    36661 tatgatatta agaccttagc cttggaatgt gccacaaagc gcatgtatcc agatatgtta
    36721 tcttatgata agattattga gctgacagga tcctttaagt caccaatggg ctgtcgctct
    36781 ttccttcaag gctggaagga tgaacagggg caagatgtta cctcagggcg tatgaacctt
    36841 ggggttgtaa ccatgaattt acctcgtatt gctatggaat caaatggcga tatggataaa
    36901 ttctgggagc tgtttaacga acgattacac atttgtaagg acgctcttgt ttatcgtgta
    36961 gagcgcgtta aggaggcaac gccagccaat gctcctattc tttaccaata tggagccttt
    37021 ggcaagcggc tagctaagac tggcaatgtt gatgagctct ttaacaatcg ccgcgcaact
    37081 gtatcattgg gttacattgg cttatatgag gtagcaaccg tattttacgg tgggcaatgg
    37141 gagcacaacc aagaggccaa agactttaca atcactattg ttaaggaaat gaaaaaggct
    37201 tgcgagactt ggtcagatga atatggctat catttctctg tttactcaac accatcagaa
    37261 agcttgacag atcgtttttg ccgcctagat actgacaaat ttggcgttgt tgctgatatt
    37321 acagataaag aatactatac taattcattc cactatgatg ttcgtaaaaa tccaacacct
    37381 tttgagaagc tagattttga aaaggcttat ccagcagccg gtgcttcagg tggctttatc
    37441 cattactgtg agtaccctgt tttgcagcaa aatcccaagg ccttggaagc tgtttgggac
    37501 tatgcttatg atcgtgtggg ctacctaggc acaaatacgc caattgataa gtgctatgaa
    37561 tgccattttg agggagattt caccccaaca gagcgaggct ttacttgtcc aaattgtgga
    37621 aacaatgacc ctaagacagt agatgtggtt aaaagaacct gtggttattt aggaaaccct
    37681 caggctcgtc caatggtcaa tggtcgtcat aaggaaatct ctgctcgtgt caagcacatg
    37741 aacggatcaa ccatcaagta tccggggata taagccttgg agaataatct cattacacct
    37801 atatcattgt aaaggattgc ttcatgcaag cagtccttta gttatcaaga caggtctgta
    37861 acaaagaaag ggagaaacat gggaaaatac cagttagatt ataagggaat gcagcaagta
    37921 gagaggtttc atgagaaaca ttctgttgca aaaacagaca aaaagtctcg agtacagcag
    37981 cttagagcac aatttttaga aaaagcaaag caatcaaaga aataatggca cactcagtaa
    38041 aggcggtgaa gaatgctaga tattggaatt gttgggttag gcgctatttc acaaaaggcc
    38101 tatttaccct atatgcgtca attaagagga atcaattggc atttatctac tagaaatgcg
    38161 ttagtccgcc aggaggtggg tcagcttttt ggttgcgcaa ggctttacag cactgtcaat
    38221 gagttacttg aggctaagtt agatggtgtg tttatccatg cagccactaa ggctcattta
    38281 gagctggcta gtttgttttt acaaaaagga attccagttt acatggataa gcctttgacg
    38341 gaggatttct ttagcacgca ggctctttat caattagcag ataagcacaa tacctttttg
    38401 atggcagact ttaatagacg ctttgcacct ggtgtcaaga agttgtcaac cctgtcaacc
    38461 aaacgtaaag ttgttgttga gaaaaatgat attaatagac caggtgacaa acagtttaag
    38521 ctttttgact tctttataca ccctttagat acagctttat ttttagttga taggaggctt
    38581 gttgcaggct attttcatta tcagctgact gataatgatt tgctaagtca ggttagtgta
    38641 accttaagga cagaacagac tattatttca gcagctatga atctacagtc aggtagcagg
    38701 cgtgaggtga tggaggttca gacacctaaa gagacctatc acctagaaaa tctagagacc
    38761 ttgcgagctt atcgaggggt tgatcaagag atcaagggat ttagtgcttg ggatactacc
    38821 ttatctaaac gaggctttga ggctattgtg gattcttttt tacaggctgt caaggatggt
    38881 gttaaccctg tcaagccaga gacaagtctg ttgagtcact ggatttgtca ccaaatttgt
    38941 caatctcatg aagctgatgg catattagat gtttctcttc ccttataaag gagtgataat
    39001 atgaagctac gaagacctaa aaagcaagat gaagcgtctg ttttagaaat gatggcagag
    39061 tttgaagact atcagtctcc tcatgatggt ggtttttgga acgctgagca ttttgattat
    39121 gaaaaatggt tggaatctaa tgctctgatg gaggctggct tagctatccc tgagaattgg
    39181 gtgcctgcca tacagctcgt tgcctttgct gatcaacagg ctattggatt tgtcaatgta
    39241 cgcttgagat taaacgaaca gctactggta aaaggtgggc atattggtta ttctgttaga
    39301 cctagccagc gtggaaaggg ctatgcaaag ctgatgctaa aggaagcctt gcagcttgct
    39361 cgtcaaaagg gcattcgtga ggttttagtg acttgtcatt gcagcaatag tgctagtcgg
    39421 tctgttattt tagctaatgg tggtcagctg aaggattgca ataagggtat tgaacgctat
    39481 tggataaaag cataagaggc aataatgaag gaaaactgtt ggaattctcc caaaccaaaa
    39541 gaatggacat cagaggcatt aagccaagga cgcgttattg attataaggc atttaatttt
    39601 gtagatgggg agggagtgcg aaactcactt tatgtttcag gctgcatgtt ccattgtaag
    39661 ggctgctata acgcagcaac ctggtctttt aaggcgggta ttccttatac gaaagagctt
    39721 gaggagcaaa ttatgactga tcttgcaaag ccctatgttc aaggtttgac acttttgggc
    39781 ggtgagccct ttttgaatac gggaatattg attcctttga ttaagcgtat cagaaaagag
    39841 ctgccagaaa aggatatttg gtcttggaca ggctatacct gggaggaaat gatggaagaa
    39901 acccaggata agctagagct gttaagcatg attgatattt tagttgatgg ccgctttgat
    39961 atcaccaaaa agaatctgat gctgcaattt cgtggatcca gtaatcagcg tatcatcgat
    40021 gttaaaaagt cactggctgc tggagaggtg gttatttggg ataagctaaa tgatggtgat
    40081 cagtcctttg agcaaatgag ccgcgatgat ttgatttagt agagacttat caacatcact
    40141 agacttgaaa gctaataatg aaagcatgat tttaggctcc tgtggtcttg cttaaccaat
    40201 ctaataaggg gttttcccca cattatcctc atacttatcc acaggttgtg aataacctgt
    40261 tggtttgtgg ataaaaaaga gaattaaggg gttctttaat tctctaggcc tgaaaaaggg
    40321 ttctttttga tgttttttct taaaagaaag agaggcaagt gacctctctt gaaatagtat
    40381 acttaggctt taagcctagc tttcaatatc tctgaatgtc tgattttctt aggagtcagg
    40441 cattttttaa tggcgatggg aagtacggct tgtgggtcgc tttgtgtgct aagaggcttt
    40501 ctgagctgct atatgtcaat gattggtgat gtgacagctg aggcttgttc acattctgaa
    40561 agcactgatg tttttcctag ctttcttttt tgatgtagta gtaattagtt tcggttgata
    40621 gctcctcatt atagcaaaag ccagcaaagc tcagctgctt aagtgcttcc ttggtttgga
    40681 cattgttttc tagacaggct gttagaaagg ctcctcgagc tttttttgaa atggttgaat
    40741 gcgtcttgag ctgtcctgat ctttcctcca taaatttggg acttatccac agtttttgat
    40801 attcctttga aaaaacatct ctaaactcgt tggataacag agaaatgatt tgcttgtgat
    40861 ctttagcaaa ctgatcgtag atagggcgcc aataatgctt aaggctttgc ccattgatgg
    40921 ttactttagt gtgaaaatca tgccggtgct ctgcgatttt ctcatcagta gggataatgc
    40981 cataaaaaga cgaggtaatg tagacctgct ttgagaggta gtcttgctgg tctttagaga
    41041 gattgtcgcg cttgagatga cggtacatga gcccattaaa gagctgataa gcaggataag
    41101 cagaactctg cccttgagct atggccttta gtctcttggc ttccttgctt gctgcttcta
    41161 tacggatgct gtaggccctt gctagctcct ctagggatag ttcagccata gcctctaata
    41221 tgggcaggct tttttgggga agctgatgtg gatagcaagg tggaactggt ttcatttctt
    41281 tagctgttgg aattaaaaaa gttaacataa gtttattgta gtaaaggcgg caaccttctg
    41341 tcaagagtgg gatacatttg gtggttatgt catatgaaac taatttttat attttttaca
    41401 ttttgattag tttttaaaaa tatagtgatt tagtgttgca taacctctct aagtatgtta
    41461 atatatactt aagtctgttt gataaacaga agctcaggtc aagtgagtgt tccacttaca
    41521 ataacgcagt tgatgatggg gagactcaga ctcagactca gactcagagt caaggaaaag
    41581 aaatatagtc ttgtaggatt acctacaggg cttttttcta ttttgaattg agagatcaat
    41641 ataaggtgat gtgctgtttt ttattacctt aaacatttgg atattggcta ttgacaaaaa
    41701 gtgtaaagga aactatacta tatgtgtaaa gttaacttga catattggag gaaccatgga
    41761 aaatcggata caagaactcc gtaagtcacg agggattagt caagctgatt tggcagatat
    41821 gatgtgtgtc actaggcaaa ccattatctc cttagagaaa ggacgctata atgcgtcatt
    41881 agagctggcc tataaattag cgacattttt caatctgact atagaagacg ttttcttgtt
    41941 tgaagagaag ggagaatgag atgatattta gtgatttaag cgtcctgctg actcaaaaaa
    42001 gccagctagc ctatgccaaa aggctgaagt atatgggctt tttcgctctc tgtttaggcg
    42061 gtttgttttt gttgctggcc tttgacgtga gactgacgag ctttgctcag ggaatgctgg
    42121 tagggcttgg tagtggtagc ttattattag gtgttcgtgc tttttcagat tgcctttaat
    42181 cctcaaaggc tgagagcctc ttatattaag gcttatgatg agcgtcatca ggtagttatc
    42241 aagctagctg ctgtatcaac cttaatctta ttagtggtgt tgattattgg ctgtttgtgc
    42301 ttgaatgttt tttggagttt ggtttttggc tttagagtat ttttagagat ttgtctgtat
    42361 acgatcttgc ttggtttttt aggcatcaag ctattgttag agcatatgat ttaggaggct
    42421 tcaatggaaa caaaacattc agcagtaaag gtcatcatca gtaaattaaa atggtttggc
    42481 ttagctcttc ttgtgtttat gcttgagcag gctccaacat ttttgataac aaaagaacag
    42541 ccaatgtggc agacacttct tcttgtggtc atttttcttt tgattagtgg aggtacttat
    42601 tacctagctg tgaagcttca cattgtggga gatcaagcta ttcctaagaa tgactatcgg
    42661 gcactttgga ttggtttggg agtggtagct gtctttgttg tcaagatgat tggtggtatt
    42721 ctgttgtttt tggagcatgg tccgggagcc aatacggtca atcaagctgc cttagaacag
    42781 gcaggcttat ctccgattct tatggttacg ctagttgcta ttgtggcacc aattgtggaa
    42841 gaaattgctt ttcgagggct gctttatggg aagctctttg gtgcagagtc ttatctgggc
    42901 ttgattttta gcagtatcat gtttggcttg attcatgtgc caacagattt tggcagttgg
    42961 tttatctatg gcggtatggg gctggtgtta ggctttgttt tccataaaac aaagaaggtc
    43021 gaatacacga tattgattca ttttttgaat aatgcactag ctgttcttat catgcttttg
    43081 ctgccttatc ttcagtagta ctgcttgagt aatgaagggg gtaatgaatg aaaaatgatc
    43141 gttggattga caaaaaatat caacgttggg agaaagtgta taagagactt ggtcattctt
    43201 tactgacaat cggtgtgttg gtagggactt atgggatttt tttgattatt caagggaatc
    43261 atcaaacggg ctttctcctt tttatcctgg ggcctatact attgattgcg tcatgtcttt
    43321 gctattatgt gtttacagag ccaacgtctt tacgagaata tctgattaat agctatgatg
    43381 agcgtaaccg agctattcgt cagaaagcac aggcctactg cttttgtcta tttgcttttc
    43441 tctttttgat gcttgcgata ttctttccaa atatgacgat caaggagctt tttgggtata
    43501 atcttccgtt gattgttttc aatctgtatg tcatgattag agcctgggtt agtaaacaca
    43561 tgtaggtcat gttaacacaa aggagtctag agcaagggct ttgaatgaaa ctatttttct
    43621 aaaaacgcaa aaaatcgcgt gcagtaacag attaggccat gttactgcat gcgattttgt
    43681 tgtttcaaac gtgagctcag aatgacatat cctttttaga aagaataggt atttagggct
    43741 gtcttgagct agtcttaggt aatgagcttg gagctcattg gtgatggtta ggataggtct
    43801 ttagcttttt tgatcgttgt gtcaatggca gagcagacag aatgtgtcag gcctgttttt
    43861 tcaagatcca tcaagcctgc aatggttgtg ccgccgggac tgcagatctt atcaatcaaa
    43921 tcatggggac tatctgtgct gactagcagg ttcttggcgc tagctaggac agtttgacta
    43981 acgatactaa gggccttgtc tttaggcagt ccatttttga ctccggcctt tgccatagct
    44041 tcgatgaaaa ggtaaagata agcaggactt gaccctgcta gagcagtaaa ggtatcaaaa
    44101 tccttttcag ctatttcaaa ggttgttcca aagctgttgg ttagctcttt agcagtagct
    44161 aataaatcag cagttactaa gtcattacca gtcaaagcag tggtgctttg gagaatttga
    44221 gcattcatat ttggcatgat acgtaggagt ggcaaatgag agcttgttaa ttgagctagt
    44281 ctgtctaagg aaataccagc agccattgac atgataggct gtttgaactg tagagggcta
    44341 agaacagtct caaagagctg tggcttgatc cctagaatga tgaagtcaac ctgatcgatc
    44401 agctcttggt gagattgggc gtagcttagg tgcaattggc cagcaatttc tttagagcga
    44461 gctaaggatg agcctgagat gattagctcg tgtggtgtgt gtgttaggcc ttgaatgata
    44521 gcagttgcca ttttgccaac accgataaat ccaattttca taataatgtt cctaaaaatg
    44581 aataaaggct caataggcta gagtgctcat tgaaccttag attcgcattt tagccttatc
    44641 cttcctagta tttcttgatt aaatcaactg ttgagcggtc aagctttttg acaatggctt
    44701 gcaaaaaggc ctgtgcttct acgaaatcat ctaaggcgta caagctctga tgtgagtgaa
    44761 tgtagcgagc gcagacaccg attgtggttg aagggatacc gccattttta aggtgagcag
    44821 caccggcgtc tgtaccgcct ttaccacaat aatattggaa ggcaacccca gcctcctcag
    44881 cggtggttaa taggaagtct cgcatgttct taagcatgat gtgtccggga tcgtaaaagc
    44941 gtagaagggt tccatcacca atatggccaa gattgccata aatatcacca gcaggtgagc
    45001 aatcaacagc aaagaaaagc tcaggatcaa atgtagtggc tgacacatgg gcaccacgaa
    45061 gcccgacttc ttcttggaca tttgctccag caataagggt gttgtgaagt gtctggtctt
    45121 ttagggcttc tagcagctca gtgaccatga gaacaccata gcggttgtcc caggcctttg
    45181 agatgatatt ctttttattg gcagttaaaa tggtttcaga ctgcggtaca ataatatctc
    45241 ctggtgtgat gccaaagctt tcggcttcag ttttgtctgt aaagccacca tcaaaaacaa
    45301 tatctgaaac cgctggcaga ctagcagcac catttgcccc gcgcagaaaa tggggaggaa
    45361 ctgagcctga aataacagga atggcttggc cagcgcgagt gtataaggta aagcgctgtg
    45421 agctaacaac tagtggattc cagccgccaa tttcaacaac ccgcagtgtt ccatcagctt
    45481 taatctcgct caccataaag ccaacctcgt ccatgtgagc cgcaacaaga atgcgaggag
    45541 cttgatccgc cttgctttct tttatcccaa atatgccgcc aagtccatca acctccactc
    45601 ggtcaacaag cggcgtgatc ttagcgcgta agtaatcccg aacagtgtgc tcgtagccgg
    45661 cgatgccgtc taattcagta acttctttaa tttttgaaaa taaatcaatc atttgtatac
    45721 tccatttgtc atgtaagatt aaaggtatca cgtctgcctc tattctatca ttttttagtg
    45781 aagaatggga aacagcttga gcataggaaa agagtttggg agattaggtg tgtctttctt
    45841 gcttgataag ctgcttatta tcagtttgat tcagatgaga taactgctgg tattgatgga
    45901 atgaaacagc tatgcacaac agccttgaca aggatcgaca ggcctgagct gtcttatgct
    45961 atcaattgca cttaggtaga gcagtagcct gatattgatg tgattagttg ctcttgtcag
    46021 gtggtttatt agtatttcct aaagtgtcag ctagtcttgg ctgagattgt tagcttttgc
    46081 tctagcctat tattcccttt ttgtgataaa atgaaaggta tgaatggaaa aaagacacgt
    46141 attgtttcag gattaattgg actgggtctg ctagccggct tgggattgag gcttaaggaa
    46201 gtctatcaag aaagagagcg tcagagagta ttggttgaat tgcgcgcctt tttctcagcc
    46261 ttaggagaga ttgaggtctt gtacatcaac tcctttagct caaagcgtga tgatgtcact
    46321 ggtggccttg tcatgacaga tggtaagacc tatacttacc attaccacaa aggaagtatt
    46381 gattttaaag aggatttgac atgattattc caacatctaa ggaagaactt gctaggctaa
    46441 ttgagacaga gcctaggctg gttttgtttt ttacagcaga ttggtgtccg gattgccagt
    46501 atatctatcc tgtaatgcct gagctagagg ctgaaaaccc ggatatgacc tttgtccgcc
    46561 ttgatcgcga tgattttatc gatttagcgc aggattggca aatttttggc attccaagct
    46621 ttcttgttat ggaaaagggg caggagaagg gccgtttggt caatagatta cgaaaaacaa
    46681 aggctgagat tagtgacttt ctagcagcct atcactaaga ggagaaaatg agatgatttt
    46741 tgcatataat aaagagcagg tcggtgatgt tttgatggtg atactagagg ataaaaaaga
    46801 catcaagcga caggttgagc gtaaggggag agtagcgcgt gtttttgcag aagagacagg
    46861 gcaaaccctt gcttggaata tttttgaggc gtcagcctta atcgctgttg agggaaatgg
    46921 gcaggttttc ttgtctgagg aggagttagc gattttaaat gcggagcttg ctcaagaagg
    46981 gtttactgaa cgattagagg ctagcccagc ccctgttttt gttgtggggc aaatcattga
    47041 gatgattcct cacccagata gtgatcattt gaatatctgt caggtacaga ttgctcctga
    47101 taaggctgtg caaatcgttg caggagcacc taatgctgct gttgggttaa aaacaattgt
    47161 tgccttgcca ggtgctatga tgccaagtgg cagccttatt tttccaggaa agcttcgtgg
    47221 gaaggaaagc tttggtatga tgtgttctcc acgcgaattg gccttgccaa atgctccaca
    47281 aaagcgtggt attattgagc ttggtgatgc tgcagcggtt ggtgaagcct ttgatcctgc
    47341 taagcattgg cagagctagc aggacttgat cagcattaaa atggtgttta gtccttcttt
    47401 tgcttggtga aaagcctttg gaccttgagc catgcagtgc tttttgctgg tctgtgactg
    47461 tctttagctt caggatcgaa gcattagagt agctgcttaa cttattgtca gcgctgttga
    47521 ttgcagtagc gctatgcttg tgacaagtga aggcaaagcc tatcaatgcc cttggctagg
    47581 gctaaaaatt gtctttagag tcacttttga ggtgagtagc tcgctaattt cggtattgaa
    47641 cggtgcttag gtaccgtttt tttaagcttt gctgagtgtg acatgctgaa aaaaggccat
    47701 gtctttatat ggcttttggt cacagatggc taattcaatc gtccgcaaca cttccagcca
    47761 atcaggctta gctttaacct catttggttg aagtccgtag catgtccgca gtccacgata
    47821 gccttggagc ttcaaatcgg tctttctgag taagtcatca atactgtagg tctgacctgc
    47881 tgcaaaggat aaactttcaa aggcttgtcc atttagcaca ttaagtgcct tgtcatagtc
    47941 gtgttcaaaa ataacagagt ggagaacttt tccgacttga ttgtgcttga tgagtgatag
    48001 ctgcccttta ggcttcaata gacgttccat ctgagctagg tagatcgcat gctcttttgg
    48061 ggcgatatat tctaagacat tgtggcatat gatcatatca aaggcttgat caggcagttt
    48121 ttctagcgct tctaatgaac cttttatttt atgaatgctt tcttgctttt gggcaaataa
    48181 taggtcagga tttggctcaa ttgcagttac ttcattctgg acggctaatg cctctgctgt
    48241 gatgcaaaag cctgctccga aatctaaaat agtcttgcct gctatggggc ctaattgggc
    48301 aaagatcaaa tcatacatga gctttcccca gggccttgtg agcatgtctt gataggcttt
    48361 aagattaata gtcattatct agttttcctt tctttagctg ctgtgagcta ttggcaggat
    48421 ttctaaactt cacagcttgt ccttatttta ccatgtttta cgaataataa gataaggagg
    48481 tatgacatgt acaataaagt aatcttgata ggccgtttag tggccaagcc agaattaaac
    48541 aagacattaa cggataagca ggtcgttcga tttaccttag cagttaatcg tcggtttaag
    48601 acgacgactg gtgagcgtga ggtggatttt atcaatgctg ttgcttgggg aggtttggct
    48661 gaaaccttgg cttcctatgc tagcaagggg agtctgctgt cacttgatgg cgagcttcgc
    48721 acacgaaaat atgacaaggc gggtcagact cattttgtga cagaggtttt gtgtcattct
    48781 tttcaattgc tggaaagtcg agcgcaacga gctatacgtg aaaacaacgc tgctaatgat
    48841 ttgattgatt tggctttaga ggaggaaaag cttccctttt aaagacagct gctagcttac
    48901 tgtcgctaag ggagtcagac actagcattg tgtatgctag agatctcaac ataatctaaa
    48961 aaatggcaac gattctaaaa aaaatcttga cacgtcttag aaaaaggttt acaatgtatg
    49021 acaattaaaa tgaaagaaaa caggaggtgc tggtatggta gcagttagca cagctcagac
    49081 gatgactaag cgttattact ttagcttctt tagatagtgt ttgtagacat gagcgcatgg
    49141 atacaaacac actgaacgtt atgtttgtat ctatggggct aagggctatt tgagttgttt
    49201 gtccacatag atgatatctc ttctaagtgg acaccataca gcatgtattt tgttatctca
    49261 tgatacctgt ataggaccat ttagattatc tagatggtct tatttttatg caagaaagag
    49321 gaaatgacat gagatttaaa cagttatcct taacagcctt tatagggctt ttggcaatgc
    49381 tgctaacggc ttgtcgacaa gaaaccaacc aaacacatca agctgctaga gttgggatta
    49441 ttcaatatgc tgagcactca gccctagatg ctgcgcgtga gggttttatt gaggcgcttg
    49501 agcagggcgg ctttagagag gggaagaacc tgaccattac aaccaaaaat gcacagggtg
    49561 atcaggctaa cctgcaaaca atggtggagc agctggcggg taagaacgat ttgcagcttg
    49621 cgatcgcaac gccggcagcg caggcgcttt taaatatgga ctcagagaca ccagctgtat
    49681 ttacagcggt aacagatcct gtctcagcag gtctggttga tacattagct aagcctggtg
    49741 ggaatatgac aggctctaca gatgcgactg atgttgagaa tcagattgat ttgttgacca
    49801 aggcgctgcc tcaagctagg acagttggga ttttctacaa ttcaagcgag gtgaattcgg
    49861 agatacaggc taagaaggcc aagagggagc ttgagaaaaa aggcttaaag gtccttatga
    49921 aaaccgtaac cactactaat gatgtgcagc aggttatgac aagcttggct agtcaggttg
    49981 acgctgttta cctgccaaca gataatacgg ttgcctcaac agctactact attggggata
    50041 ttttaaagga ggccaaaatt ccttcaatgg gaagcgatgc tgcttacctg agtgctgttt
    50101 tgttcacctc aggtgttgat taccatgcta ttggcatgca ggctggtcag caggcggtag
    50161 atattttaaa gggtaaaaaa ccagcaagca ttcaggttgc taagcctcaa aaggcaagca
    50221 ttgctgttaa tgatgatatg gcaagacttc tgggcattga ccccgaggtg atcaaggctc
    50281 ttgcaagtaa cggagccaac tagcgtttta ggaggaaggt atgaaaaaag gaagctattt
    50341 aatactgtta gtgcttgcag gcttcgtttt ggtggcttgt cgttcgacag ctagtcctcg
    50401 taaggttaac caatctcatg ttaacatcgg tattttacaa tacatggaac atgattcgct
    50461 gacggcagct cgtcgaggct ttgaagcgca attaaaggca gcgggctata ctaagggaga
    50521 caagctgagc cttcattatc aaaatgcaca gggcgaccaa gctaatttac agacgatttc
    50581 agagcagcta gtgaagcaaa atgatttgat cttggcgatt gcgacaccgg cagcgcaagc
    50641 cttagcgacc gtctcatcag atagaccaat tgtttttaca gcagtaacag atcctatctc
    50701 agcaggctta gtggatagga tcaaaaagcc tggtggcttg ataacaggaa caagtgacca
    50761 ggcgccgatt gcaaagcaaa ttgacttgtt agcccaagcc ttgccagagg ccaaaactat
    50821 tggcatttta tacacagcta gtgaacgtaa tgctgaggtg caggtaaagg aagctgaaac
    50881 gctactgacc aaggttggtt atagggttat taaaaaggga attgccactt caaatgatgt
    50941 gcaagatact gctgcaagct tgatgagagc agtagacgcg ctttttgtac cgacagataa
    51001 taccgttgct tcaaccatga caatgctggg tgagctgtca ttggctaata aggttccaat
    51061 tattggtggc tcaacggata tggttgatgc aggtgggctc ttgacctatg gtatcgacta
    51121 cgagagcctt ggtagacagg ctggagaaat ggccattaag attttaagag gacaggatcc
    51181 agcaagccta gcagtggagt acccaaaaac agtcaagcta catatcaatc aagcaatggc
    51241 agacaagcta gcgattgata cttccacatt atcagttgac taaattgcta ggttaaaggc
    51301 taaatgactg atctctagcc agctggctaa atgacaaagt cttaaccagt tagcttagct
    51361 tactattaac gattcatatg acaaaaaagg agaaatcatg tcactcattt tatcgagctt
    51421 atcacagggc ttattgtggt ctattatggc aattggtgtt tacctgacat ttcgtatttt
    51481 agatattgcc gatttaactg cagaaggttc ctatccgctt ggggcagcta tttgtgcaac
    51541 gggtattgta tcaggtgttt ctcccttgct ggctacgttt ttagctttta ttggaggctt
    51601 gctggcaggc cttgtctcag gattagttca caccaaatta aaaataccag ccttactaac
    51661 aggaattatc actctgacag gcttgtattc tgtgaatcta aaggtgctag gaagagccaa
    51721 tgtggcttta ttacgtcaaa gaactttagt tacccagctc tatgatctag gctttaccaa
    51781 gcttgcagcg gtgctaatta tgggctttgt ctttgtgacc attgtgattt ttttattagc
    51841 cctgctgatg aaaactcagc ttggcctagc tctgcgatcg accggagaca ataatccaat
    51901 gagtgaagcc aatggtatca aaacagatca gatgaaaatc atggggtata tgctatctaa
    51961 cggtttgatt gccctatgtg gtgccttgct ttgtcagaat aatggctatg cagatttaaa
    52021 tgctggtgtt gggacaattg ttattgggct ggcttcgatt atcattgctg aggtgatgat
    52081 taggcagcta agcattggct ggcgcttagc ttccattgtt ttaggctcta ttgtttatcg
    52141 cttaattatt ctagctatcc tagccattcc cggtatggat gcagatttgg ttaagctttt
    52201 ttcagccatg ctattggcag ctgttctttt tgtgccagaa ttacagcaaa ggcttcgcct
    52261 tcgaaaaaca agtttaggat aggagaaatc atgtcagcaa tattatcaat taaggctatt
    52321 cacaaaacat ttgaagcagg tacgattaac gaaaatcatg tcttgagagg cttatctttg
    52381 gacattgagg agggggattt tatctcggtt atcggtggga atggcgctgg aaaatccaca
    52441 ttaatgaata ctctagcagg cactctggct tttgatcagg gcgatattct tttagaggga
    52501 aaatcaatca agcatttatc agccgctaag cgtgccaagg acatcagtcg agtgtttcaa
    52561 gaccctaaga tgggaaccgc ttcacgcttg accattgagg aaaatatggc tattgcttac
    52621 cgccgaggga aatcaagggg gctaggctgg ggcgttaaag aaagagagcg ccagatctat
    52681 cgtcaggcct tgcaggaatt aggcctaaat ctggaaaacc gtcttaaggc cgagacacag
    52741 tttttatcag gagggcaaag acaagccttg accctgttaa tggcttcctt agcaaagcct
    52801 aaggtcttgt tgctagatga gcataccgca gctcttgatc ctaagaccag tacaatggta
    52861 atggctttga caaagcagct tgttgagaca catggcttga caaccctgat gattacccat
    52921 aatttggaaa atgctattgc ttatggtaat cgtctggtca tgctccatca aggtaatatt
    52981 gtggtggata ttaagagaga agagaaggcc aagctgacgg ttgaccactt gatggcactc
    53041 tttcaccaaa atagtggtca tacgctcctt gatgatgcac ttgttttggg ataggctagg
    53101 tgagggttag ctctgttttc aaatagcagc cataatgaaa aggcttaaag ccaacgcttc
    53161 tagaaacgct agctcaagcc ttgttataat acttaggaga tttttctaag agtgataaag
    53221 ccatgatgac gtctattgta gtcaaaggat ttgtttcgga tgcgataagc ctcattttcc
    53281 acaatttcaa ttgccttatt cagctgctga atggtaatcg cctcatcaat ctcatgaaaa
    53341 gcagtgctat aataatcctc actaacacgt tgattgcggt ctttataggt atttttatgc
    53401 tctgttaaaa tggccttagc ctcagcacgt tttgcaatgg tatctataat accttgacca
    53461 tatgctctag cctcttgaag gattgacagc atattgtcta gagaatatgc gtttgctaag
    53521 cggctgacaa agctatcagc gacctcagga cttaaattaa taccatctaa gtgataaatc
    53581 atctctgggt gtagctttag gtaatactgc aattcgcgga acaaaagcgc tggaattttc
    53641 gacgaatccc tatatggatt gagctgaatc tcctgactat gtagcctatt gataaaatcg
    53701 tccttgaact gcttaatagc atcgtagtct gatttttcta gctctgcttt aatattggct
    53761 agaatctggg cgtctgaata acgacgatag cttgatagtg aagcagcagg cctactagta
    53821 ttggaatttc gagaagcttc tgctcttcta gtctctttgc ttggtgtttg ctgcttattt
    53881 gactgagtct cctgctcggt tagtcgtagc tcagggtgta aacgactaat attgttaaga
    53941 aattggttaa cctcatattc tgatgaaaac tttagcctag gtctggcctt gaccttctca
    54001 atagccttgt caataatcct tttcccgtac cttttgagat tactgtcaga ctggatcaaa
    54061 taaagattaa catgtaagtg atcttgacta tccgccttag ataagctgtt accaaggcca
    54121 aggcttccta agagcgtagc tagtaacagc aggtgtttta ctagactacg ctgaacaata
    54181 ttgtgacgac taagcataag ttattttccc attctattgt aatataccag aaaatgttat
    54241 caaaataaag ataagatgtc aatgtcatta atggtggtta atctttaatt aatggtcgtt
    54301 aatctagtat atcagagagc tagcttaggc tggcagtggt cattctgtgc gtcttggtac
    54361 gaaatgccca agcagatgca gctcactaga atgatcaata gcctcaacac aaagcccctt
    54421 acagcttgac acaagctgta aggggctttg ttgtattaac agataactca aatccttgct
    54481 ttttataata aatctaaggt ttttagcttg tcatcaatca tgtgcagaac ggttgccaaa
    54541 tcctctgggt tttgcacgaa atcaagcttg tttccatcaa tcttcatctt aggtgaaacg
    54601 tcatattgct cataccagct tgggtattca ccatgtacct gatggtaata ggcttctaag
    54661 tcaggattgt cgtcaacctg ctcaaaacgt ctgccgcgct tttcaatgcg ctctagcatc
    54721 ttctcaaagg agacatcaat ataaatcagc agatcaggcc gtttttaagg cattccttca
    54781 agctcctcta gcatattggc taagagctct tggtaaattt caagctctgt cttggtaaca
    54841 tttccatttt tatagttaag tgtcaagaag agctcatctt caaagattga gcggtcaaga
    54901 atattattgt ctgcctggta ggcttcttta atagatttga agcgcttgtt caaaaagaaa
    54961 atttgtagta aaaaggcata ttttttaggg tcttggtaat acagatcaag aacaggattg
    55021 ttatcaacag cctcgtaaaa tacctctgtt cctaaatgct cacccagtgc agcagcaagg
    55081 gaactcttgc ctgcgccgat tgttccagct aatacaatca acatgtttct ccttctatgt
    55141 agtcttagtg tatttgtgca aaaatcgttt caacctcagc taaggtttta gcgcgtgaaa
    55201 cggcactgcg aattttggca gcgcctgctg tccctcgcag gtaatgaggg gctaacccac
    55261 gaaattcacg aacagcaata gcttctccct tgagcctgat gaggcgcttg agatggtctt
    55321 tagcaatatc tagcttttta gcaaagggca gctctggcaa aacctctcct gtctcaaaga
    55381 agtgattaat ttgggtgaag agataagggt tgttcatagc tgcacggcca atcatgaccg
    55441 catctacacc aatctcctca atcatgaacc tagcgtcctg aacagttctg acatctccat
    55501 ttccaataaa tggaatcctg gtaatagctc ttgagacgcg tgcaagggtt tcatggtcac
    55561 aggtgccagt atacatctgc tcacgagtac ggccatgcat ggcaagagct gacacaccag
    55621 cagcttcagc agccaaggca ttctcaacag ctagtgagct gtctgcccag ccggtacgca
    55681 ttttgacagt cagtggaatg tctaaaacag aggttacctc ctgaatgata tggtaaatct
    55741 tatcaggatc gcgaagccac ttggcacctg cttcattttt aaccaccttg ttaacaggac
    55801 agcccatatt gatgtcaaca atgtcagcct tggtatggct ctggataaaa tcagccgcac
    55861 gctttagtcc ttcagcgtca ccgccaaata gttggattga catggggtgc tcattgtcat
    55921 caatatgaag catatgcagg gttttttcgt tattatagag aagtcccttt tcagaaatca
    55981 tttccatgac aacaaggcct gcaccaaatt ccttggcaat cgtgcgaaag gccgaattgg
    56041 tcacaccagc cataggtgca agcactgtac ggtgagggat ttccacatga ccaatcctaa
    56101 agggtgagtt aagccttgtc attgatcagc acctccaaat cagtttggtc aaattggtac
    56161 ttggtgccac aaaattggca aacaatttca gcccccttat cctcgtttag cattgtcaac
    56221 aggtcagctt tagggaggct cattagggct gacgcaaagc gctctcttga gcagtcacac
    56281 tgaaagctca gctgctcttc agctaatcgc ttgtaaggct cttcaccata aatagctgct
    56341 aacagagcgt ctatatgatt ttccgacgct agaagggttg aaatcgcagg catttcctga
    56401 atgcgcttct catagtggct aatctcttcg acagaagctc caggcagcac ctgcagcata
    56461 aagccgccag caaccttgac cttgtcctct tgatctagaa gcacattaag gccgacagca
    56521 gatggtgtct gctcagactc tgtcaagtag taggccagat cctcaccaat ctcaccggta
    56581 atcaagggtg ttgtagaggt gtagggattg cctgttccat agtccgtaat tgtcacaaag
    56641 tgtccctgtc ccataaaagg accaaccagt acttctccag ttgctgtttt tttgatatca
    56701 acaccgggat tttgaatata gcccttgaca tgcccttttg tgtcagcaac agaaataata
    56761 tgcccaaagg aggaatcgcc aataaccttg acagtaacct tactatctcc tttttggttg
    56821 gcagctagaa tctgattggc aatcaaggta cgaccaagtg caaccgttga agatgataag
    56881 gtatgatgcc tttcctgagc atatcgaaca gtttcggtgc aatccaaaac ataggccctg
    56941 aaggcaccgg aggcagaaat tgttttaatt agtttatcca taatttctat tatagcataa
    57001 tgaacaaggc ttgtgctggt tgctttagag gaaagctgct tgaaaataga gaaacactat
    57061 ttggttaata atagcagctc tataaagcca cttaaaaaca gagcagtgct aacaaatggt
    57121 agtattcttg tccttagcac gcagtaagct aatcacctaa gtcagtacaa tcaaacaagc
    57181 atcaaaaaac agctccgata ggttgattaa aggaagaaat gataaaagag ttatttcgta
    57241 atgctttgct gataatgagc aaggtaatca tgtggtgtcg tatcagtgta ctttttgaag
    57301 gttttcaaaa aatgggtggt atcgtagaaa taaaggagct tagccacttc tccagctggt
    57361 actcctcttc gtaaaagtag cttggcttct tgtacttttt ccttcaaaat ataggtctgc
    57421 aacgaaatag aagaatacat tttaaaaaca gctcgtaaat gtgactctga gatataaaga
    57481 tgcttagcaa tatctgatac ctttaatttt gaataaaggt gcttatcgac gtaatataaa
    57541 atactattat aaatttgctg cttatcagaa acacttttgt tagtcaatga ttctgagagg
    57601 ctaataatag cagctgctct tatttgaagc accttaagga gatctgtagc tttttcagtt
    57661 aggttcataa aatgcttaat gcgctcgtag tttttggcaa catcagtatt ttcagtaaag
    57721 cttagttcaa gcagcttaat aaaataaata atagaaagat ttttttcagc tcttaatgcg
    57781 ggaatagaag aggagacgac atctgatgaa gggatacaat tgatttcgtg ctttaatagc
    57841 tctgtattac ccagcttgac taaatcaata atatgattca aataatttaa gacagctggc
    57901 acatgaaatg acggggtatt ttccaattcg agattagcta taatatgagg atcctcccag
    57961 attagctggg cttcctccag taaatcatta atgctttgct ggcagctcat ttcaaagttg
    58021 gtgtcaaaaa aggcatcaac agctatcaaa aggcttcgaa tatgagaagc aggaaaatga
    58081 ggaatggtag agatatagcc aactagctct ttttttgact tatcaggata gcgcttcaag
    58141 aagctatcgg ctaattcctc cttatagcta tcctgaaaga aagaggtgta aaaaggccca
    58201 atgaaaataa acttgtcacc aataggaaac attagagagg attcctcaag cgttccctca
    58261 taacaagtga gctcagtatt actaggaata tctaatgttt taattaattc atagtagggg
    58321 aatcgacgct cctcgtcatc ataagcctga aggagctcaa gattttgaga aagcactaaa
    58381 acaggtaatt gtgataggtt atg
//
LOCUS       DARYYD010000004        57981 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.004, whole genome shotgun sequence.
ACCESSION   DARYYD010000004 DARYYD010000000
VERSION     DARYYD010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 57981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57981
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.004"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            67..1059
                     /locus_tag="TV188_000181"
     CDS             67..1059
                     /locus_tag="TV188_000181"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEL1533579.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLIAKLDVVEVQGPILSRVGDGM
                     QDNLSGVENPVSVHVLNIPNATFEVVHSLAKWKRHTLARFGFNEGEGLVVNMKALRPD
                     EDSLDQTHSVYVDQWDWEKVIPDGQRNLAYLKETVETIYKVIRLTELAVEARYDIEAV
                     LPKKITFIHTEELVARYPDLTPKERENAITKEFDAVFLIGIGGVLPDGKPHDGRAPDY
                     DDWTSESENGYHGLNGDILVWNEQLGTAFELFSMGIRVDEEALKRQVDITGDQERLQF
                     DWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKKHIGEVQTSVWPQEVRDTYDNIL"
     gene            1231..1770
                     /gene="rsmD"
                     /locus_tag="TV188_000182"
     CDS             1231..1770
                     /gene="rsmD"
                     /locus_tag="TV188_000182"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEL1533580.1"
                     /translation="MRIVSGEFGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFKGGR
                     VLDLFAGSGGLSIEAISRGMSEAVLVERDRKAQAIIQANIKMTKASQQFTLLKMNAER
                     ALDHLSGQFDVVFLDPPYAKETIVANIEALVEKNLLSDDVMIVCETDRSVALPEAIAW
                     LGIWKEKQYGISKVTVYVR"
     gene            1760..2260
                     /gene="coaD"
                     /locus_tag="TV188_000183"
     CDS             1760..2260
                     /gene="coaD"
                     /locus_tag="TV188_000183"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEL1533581.1"
                     /translation="MSGKIGLYTGSFDPVTNGHMDMIKRASHLFEHVYVGIFNNPNKQ
                     SFFTFELRAQMLSEAVCALPNVTVVSAEHGLAVDLARELSVTHLIRGLRNTADFDYEI
                     GLEYFNHRLAPDIETIYLMATHDLQPVSSSRIRELIAFRAPITGLVPQAVINQVEKMN
                     ENNKKN"
     gene            2238..3275
                     /locus_tag="TV188_000184"
     CDS             2238..3275
                     /locus_tag="TV188_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEL1533582.1"
                     /translation="MKTIKKIKWWLIGFVALLFLLLTLFFPLPYYIEMPGGAYDIRSV
                     LTVNGKEDKEKGAYQFVVVSLSRATLAKLLYAWLTPFTEISTMEDTTGGYSDADYLRI
                     NRFYMETSQNSAVYQALTLAGKEVSFDYKGVYVLDVSKDSSFKGVLHLADTVTGVNGK
                     TFTTSADLIDYVSHLTLGDEVQVQFTTAGESKTEKGKIIKLKNGKNGIGITLTDHTQV
                     ISGDEVDFSTGGVGGPSAGLMFTLDIYDQINHEDLRKGRVIAGTGTIGKDGKVGDIGG
                     AGLKVAAAAAAGADIFFVPNNPVHKDVKKANPKAISNYEEAKKAAKRLKTAMKIIPVK
                     TVQDAISYLKK"
     gene            3837..4451
                     /locus_tag="TV188_000185"
     CDS             3837..4451
                     /locus_tag="TV188_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEL1533583.1"
                     /translation="MKRDILPEMYNYNKFPGPEFIHFDHYVKAEGIELLLLKNEKNAF
                     NTTSFGQRFTEILLKYDYIVGDWGNEQLRLKGFYKDHHDVKKASRISRLEDYIKEFCN
                     FGCAYFVLENPNPKDMPKEEERPSRRRKSSKANRRRNQPQHSQQAPAKDNFKKLTKDR
                     SADKPSFTSKKRPAPNKTKGNQRRSRTSQLNHKTDHFIIRKKDN"
     gene            4455..5537
                     /gene="rlmN"
                     /locus_tag="TV188_000186"
     CDS             4455..5537
                     /gene="rlmN"
                     /locus_tag="TV188_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEL1533584.1"
                     /translation="MKPSIYGLTRDELIAWAIDNGQKAFRATQIWDWLYRKRVQSFDE
                     MTNISKEFVAILKDSFCINPLKQRVAQESADGTVKYLFELPDGMLIETVLMRQHYGQS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNSGEITAQIMMVQNYFDKRAQDERVSHVVVM
                     GIGEPFDNYQNVMTFLRTINDDHGLAIGARHITVSTSGLAHKIREFANEGVQVNLAVS
                     LHAPNNELRSSIMRINRSFPLDKLFSAIEYYIETTNRRVTFEYIMLNKVNDGVEQAQE
                     LADLTKRIRKLSYVNLIPYNPVSEHDQYSRSPKERVAAFYDILKKNGVNCVVRQEHGT
                     DIDAACGQLRSNTMKKDRQKAAAART"
     gene            6819..7349
                     /locus_tag="TV188_000187"
     CDS             6819..7349
                     /locus_tag="TV188_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEL1533585.1"
                     /translation="MTNTLVENIYASVTHNISKKEASKNEKTKAVLNQAVADLSVAAS
                     IVHQVHWYMRGPGFLYLHPKMDELLDRLNANLDEMSERLITIGGAPYSTLEEFSQHSK
                     LDETKGSYDKSVAQHLARLVEVYLYLTSLYQVGLDITDEEGDAASNDLFTAAKADAEK
                     TIWMLQAERGQGPAIF"
     gene            7722..7955
                     /locus_tag="TV188_000188"
     CDS             7722..7955
                     /locus_tag="TV188_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEL1533586.1"
                     /translation="MKTLYDVQQLLKGFGIVIYMGKRLYDIEMMKIELQRLYDGGLLD
                     KQAYLTAELILRREHRLELKREGQENESKIDRD"
     gene            7930..8901
                     /locus_tag="TV188_000189"
     CDS             7930..8901
                     /locus_tag="TV188_000189"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEL1533587.1"
                     /translation="MSQKLIGIDLGGTTIKFGILTSEGDVQEKWAIETNVLEDGKHIV
                     PDIVASLKHRLDLYGLTKDDFIGIGMGSPGAVNRTDHTVTGAFNLNWRGTQEVGSVIE
                     RELGIPFAIDNDANVAALGERWVGAGDNNPDVVFMTLGTGVGGGIIADGNLIHGVAGA
                     GGEIGHMIVEPLKGFACTCGSQGCLETVASATGVVKVARLLAEAYEGDSSIKAAIDNG
                     EAVSSKDIFVAAEAGDAFANSVVEKVSYYLGLAAANISNILNPDSVVIGGGVSAAGEF
                     LRSRVEKYFMTFTFPQVRQSTKIKIAELGNDAGIIGAASLARQFITE"
     gene            8911..9291
                     /locus_tag="TV188_000190"
     CDS             8911..9291
                     /locus_tag="TV188_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEL1533588.1"
                     /translation="MSPLTMIGWVLLAGVIAYYLWNYVSYRRMAKQVDNDTFKELMRQ
                     GQVIDLRDPASFRARHILGARNFPAQQFTTSIKALRKDKPILLYENVRPQYRVKAVKT
                     LRKAGYTDLYVLKAGLDYWNGKVK"
     gene            9687..11528
                     /gene="typA"
                     /locus_tag="TV188_000191"
     CDS             9687..11528
                     /gene="typA"
                     /locus_tag="TV188_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEL1533589.1"
                     /translation="MTKFREDIRNVAIIAHVDHGKTTLVDELLKQSHTLDERKELQER
                     AMDSNDLEKERGITILAKNTAVAYNDVRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLTPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LEFPVVYASAINGTSSLSDDPADQEKTMAPIFDTIIDHIPAPVDNSAEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERKEIQEAKAG
                     DLIAVSGMEDIFVGETITPTDCVEALPVLRIDEPTLQMTFLVNNSPFAGREGKWVTSR
                     KVEERLLVELQTDVSLRVEPTESPDKWIVSGRGELHLSILIETMRREGYELQVSRPEV
                     IIKEIDGVKCEPFERVQIDTPEEYQGAIIQSLSERKGDMLDMQMVGNGQTRLIFLIPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPVVAGEIGGRHRGALVSIENGKATTYSIMR
                     IEERGTIFVNPGTEVYEGMIVGENSRDNDLGVNITTAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAARDKANKKKKSAE"
     gene            11610..11864
                     /locus_tag="TV188_000192"
     CDS             11610..11864
                     /locus_tag="TV188_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEL1533590.1"
                     /translation="MFYLIIAALITSYYLFMAPKSVRNTLGMIGLVGLVALLIVLAGL
                     SFIKIMQTPKEIFVGLAMIVLGYYALRDIQKIPKKPKSKH"
     gene            12010..13371
                     /locus_tag="TV188_000193"
     CDS             12010..13371
                     /locus_tag="TV188_000193"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEL1533591.1"
                     /translation="MKTITEFQNKKVLILGLAKSGEAAARLLARLGAIVTVNDSKPFE
                     ENPAAQALLEEGIRVICGSHPLELLDEDFYCMVKNPGIRYDNPMVVRALDKAISILTE
                     VELAYLVSEAPIIGITGSNGKTTTTTMIADVLNAGNHSALLAGNIGFPASEVAQAATA
                     KDILVMELSSFQLLGTEQFQPHIAVITNLVPTHLDYHGSFEDYIAAKWRIQHRMTDKD
                     YLVLNADQELVKSLAQKTKASPVFFSTKEKVDGAYLADGYLYFKEERLMSAAELGVPG
                     RHNIENALATIAVAKLRGISNQVISRTLSHFRGVKHRLQLVGTLNQVTFYNDSKSTNI
                     LACQKALSGFDNSKVILIAGGLDRGNEFDELVPDLVGLKKMILLGESAERMKRAADKA
                     GVSYLDAKDVAAATKIAFEQAKAGDIILLSPANASWDMYPSFESRGDEFLAAYDALKG
                     EAQ"
     gene            13368..14450
                     /locus_tag="TV188_000194"
     CDS             13368..14450
                     /locus_tag="TV188_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEL1533592.1"
                     /translation="MTKKIIFTGGGTAGHVTLNLILIPKFIKDGWEVHYIGDDKGIEH
                     QEIKKSGLDVTFHAIATGKLRRYFSWQNLLDIFKVGFGVMQSLFIIARLRPKALFSKG
                     GFVSVPPVIAARLLGVPAFIHESDLSMGLANRIAYRFATTMYTTFEQEQTLAKLKHVG
                     AVTKVTGPGSRSVTSKQLEAVLEYFDPNLKTLLFIGGSAGARVFNRFITDHPELKEDF
                     NIINISGDPSLNELSWHLYRVDYVTDLYQPLMEMADLVVTRGGSNTLFELLAMRKLQL
                     IIPLGKEASRGDQLENAHYFTTRGYAEQLLEQELTLPHFQEKVREVFAKQSDYLSAMK
                     SSSELQSPESFYQLLSADISSATKEN"
     gene            14451..15641
                     /locus_tag="TV188_000195"
     CDS             14451..15641
                     /locus_tag="TV188_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HEL1533593.1"
                     /translation="MADKTKHSEEKAALTEWQKRNIEFLNKKQQQAEKDKKLKEKLLN
                     EKIAQAQGEAASKADQEDTDEAEEKTEVSQAGTDEGEPLPEASEQEVPSPKDKPLKVP
                     KEKSPKQQALQKGWPVLLVSFVVLCLSIFMITPYSKVKDFSVKGNKKTSVEDLVRDSG
                     IKSSDYWITLLASPGSYENAVLKANPWVKKVALRYGFPNHFRFDVTEFDIIAYAQVAE
                     GFQLILENGKRVAAVKQAALPKSFLILNLEHEKEIQDVINRLTKIPSDLVKAIKSVSS
                     ANSQTTKDLLLLEMHDGNLIRVPRSQLELKLPYYQKIKKNLDTASIVDMEVGIYTTTA
                     EIENMPEVPASAQASQADKPAEASPEQGEEQATQEQPSPETPANPEATNPSVAQPTEQ
                     ANQQ"
     gene            15853..17217
                     /gene="ftsA"
                     /locus_tag="TV188_000196"
     CDS             15853..17217
                     /gene="ftsA"
                     /locus_tag="TV188_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEL1533594.1"
                     /translation="MARNGFFTGLDIGTSSIKVLVAEFISGEMNVIGVSNVPSTGVKD
                     GIIIDIEAAAAAIKTAVEQAEEKAGMTIERVNVGLPANLLQIEPTQGMIPVPSESKEI
                     KDEDVDSVVKSALTKSITPEREVISLVPEEFIVDGFQGIRDPRGMMGIRLEMRGLIYT
                     GPSTILHNLRKTVERAGIKVENIIISPLAMAKAVLNEGEREFGATVIDMGGGQTTVAS
                     MRAQELQYTNIYAEGGEYITKDISKVLKTSMSIAEALKYNFGQADMAEASLTDTVKVD
                     VVGSDEPVEVTERYLSEIISARVRHILDRVKQDLERGRLLDLPGGIVLIGGGAIMPGV
                     VEVAQEIFGTNVKLHIPNQVGIRNPMFANVISLVEYVGMMSEVDVLAQNAVSGEELLR
                     RKPIDFTGQEAYLPDYNETRGFEPAPNYEQQVPQADYEPQEPAEPKQKISERVRGIFG
                     SMFD"
     gene            17241..18569
                     /gene="ftsZ"
                     /locus_tag="TV188_000197"
     CDS             17241..18569
                     /gene="ftsZ"
                     /locus_tag="TV188_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEL1533595.1"
                     /translation="MAFSFDTASIQGAIIKVIGVGGGGGNAINRMIDEGVAGVEFIAA
                     NTDIQALSSSKAETVVQLGPKLTRGLGAGGQPEVGRKAAEESEEVLTEALTGADMVFI
                     TAGMGGGSGTGAAPVIARIAKSLGALTVAVVTRPFGFEGNKRSNFAIEGIQELREQVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITSPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERIVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDMTLTEA
                     EEASEIVGQAAGQGVNIWLGTSIDDSMRDEIRVTVVATGVRQDKAEQASGFRQPRTYT
                     QSNAQQAAGAQYASEQVRQTAQPSFDRRSSSFDFDMGETREMPKSQQAMPAHGHNHNQ
                     GSAFGNWDLRRDNIARPAEGELDNQLNMSTFSSNDDIDDELETPPFFKNR"
     gene            18572..19243
                     /locus_tag="TV188_000198"
     CDS             18572..19243
                     /locus_tag="TV188_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEL1533596.1"
                     /translation="MDLQKNKDIVFENIRLATQAANRPENSVSVIAVTKYVDKAVAGQ
                     LIDMGIEHIAENRIDKFLDKYEALKDRQVTWHFIGTLQRRKVKEVINKVDYFHALDSV
                     KLALEIEKRADHPVKCFLQVNISEEESKHGFKIAELDAAIEEISKMEKLHLVGIMTMA
                     PIDASQQELRSIFQKANQLRKNLQSKKRKNMPFTELSMGMSNDYPIAIQEGSTFVRIG
                     TSFFH"
     gene            19256..19918
                     /locus_tag="TV188_000199"
     CDS             19256..19918
                     /locus_tag="TV188_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEL1533597.1"
                     /translation="MAIKDAFNKMISYFDTDGVSEVEEELSSKKQEEPVTKSQQTSRP
                     NQQQQAARASQPQQPKQARPQMQAQQRPQSQSRAAYAERPYQGQSQARVSHDYNDRRA
                     TSAPSASSRREQYQHAAHQEQTTIALKYPRKYEDAQEIVDLLIVNECVLIDFQYMLDA
                     QARRCLDFIDGASKVLYGTLQRVGSSMYLLTPSNVSVNIEEMNIPNNGQDIGFDFDMK
                     RR"
     gene            19923..20180
                     /locus_tag="TV188_000200"
     CDS             19923..20180
                     /locus_tag="TV188_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEL1533598.1"
                     /translation="MIFILLILLKLIKVYSYLLLVYALLSWFPGAYDSWLGRLVSDIV
                     EPILKPFRSLNLQFAGLDFTIYLVMIGLNVLSEILIRVLIS"
     gene            20177..20971
                     /locus_tag="TV188_000201"
     CDS             20177..20971
                     /locus_tag="TV188_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEL1533599.1"
                     /translation="MTVQTMLYQHFQPDEHPFIERMLDLIARVEANYLLEVTDFLNPR
                     EVTILKGLVAATNLQCFSSTDYYPSEYGRVIVAPDYYCLDKADFDLALIEVTYNAKFN
                     QLTHAQILGTLINELGIKRALLGDIFVEIGHAQVMINRQLLSYCLGTIAKIAKARVKL
                     KEIDLDQLLNLTANQQVLTDIMVSSLRVDRLIATVLKQSRNQAIRLVEAGKVKVNYQL
                     VTKASQPVAVGDLISIRGYGRFSILTDNGFTKNGKYKLTLSKMMRK"
     gene            20981..21736
                     /locus_tag="TV188_000202"
     CDS             20981..21736
                     /locus_tag="TV188_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HEL1533600.1"
                     /translation="MALTALEIKDKTFKTKFRGYSEEEVNEFLEIVVDDYEALVRKNR
                     DNEAKIRELEEKLSYFDEMKESLSQSVILAQETAEKVKSSANAEATNLVSKATYDAQH
                     LLDESKAKANQLLRDATDEAKRVAIETEELKRQTRVFHQRLVSAIESQLSLSNSPEWD
                     ELLQPTAVYLQNSDAAFKEVVKTVLNEDIPEADDSNSFDATRQFTPEELEELQRRVEE
                     SNKELEAYQVQREEQASEPEVNLSETQTFKLNI"
     gene            22007..24805
                     /locus_tag="TV188_000203"
     CDS             22007..24805
                     /locus_tag="TV188_000203"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEL1533601.1"
                     /translation="MKLKETLNLGKTAFPMRAGLPNKEPQWQKAWDEAEIYKKRQALN
                     EGKPAFHLHDGPPYANGNIHVGHALNKISKDIIVRAKSMSGYQAPFVPGWDTHGLPIE
                     QVLAKQGVKRKEMDLADYLDMCRQYALSQVDKQRDDFKRLGVSADWDNPYVTLDPSFE
                     ADQIRVFGAMADKGYIYRGAKPVYWSWSSESALAEAEIEYHDIDSTSLYYANRVKDGK
                     GILDTDTYVVVWTTTPFTVTASRGLTVGPDMDYVVVRPAGSDRNYVVAEGLLDSLAAK
                     FAWESFEILANHKGSDLEYIVTEHPWDSEVDELVILGDHVTLDSGTGIVHTAPGFGED
                     DYNVGMTYGLEVAVTVDERGLMMENAGPDFHGQFYGKVTPIVIEKLGDLLLAQEVINH
                     SYPFDWRTKKPIIWRAVPQWFASVSDFRQEILDEIDKTTFHPTWGKTRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTKEVTDHVADLFQEHGSIIWWQKEAKELLPEGF
                     THPGSPNGVFTKETDIMDVWFDSGSSWNGVMNARDHLAYPADLYLEGSDQYRGWFNSS
                     LITSVAVNGHAPYKAILSQGFVLDGKGEKMSKSKGNIISPNDVAKQYGADILRLWVAS
                     VDTDNDVRVSMDILGQVSETYRKIRNTLRFLLANTSDFNPHTDKVAYAELAAVDKYMT
                     IKFNKLVGAINTAYERYDFMTIYKAVVNFVTVDLSAFYLDFAKDVVYIEAANSLARRR
                     MQTVFYDILVNITKLLTPILPHTAEEIWSYLEHEPEDFVQLSELPQAQTFDNQDTILE
                     EWEAFMTLRAQAQKALEEARHDKIIGKSLEAHLTIYASPEVKTLLTALDSDIALLLIV
                     SQLTISEEPAPENAVSFDDVAFTVARAQGEVCERSRRIDPTTRMRSYNAFVCDHSAKI
                     IEENFPEAVAEGFDSAAN"
     gene            complement(25283..25585)
                     /locus_tag="TV188_000204"
     CDS             complement(25283..25585)
                     /locus_tag="TV188_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEL1533602.1"
                     /translation="MRLINTTSSHPELVRNQLQNTDAHLVEVYSAGNTDVIFTQAPKH
                     YELLISNKYRAIKEDELEVIREFFLKRKIDQSIVIPGHSKTLHTNNLIEISFQTSV"
     gene            complement(25647..26096)
                     /locus_tag="TV188_000205"
     CDS             complement(25647..26096)
                     /locus_tag="TV188_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1533603.1"
                     /translation="MTVPIFGDKIDDQHYTARYGVYAVIPNSAKTEIILVQAPNGAWF
                     LPGGEIEAGESQLQALERELVEELGFAADIGYYYGQADEYFYSRHRDTYYYNPAYLYE
                     VTSFQAISKPLEDFNHLAWFLPIADAITVLKRDSHRWGVEEWQKKHH"
     gene            complement(26256..28508)
                     /locus_tag="TV188_000206"
     CDS             complement(26256..28508)
                     /locus_tag="TV188_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1533604.1"
                     /translation="MLCQNCNLNESTIHLYTSINGKQRQIDLCQNCYQIMKTDPKNPI
                     LGGYNGNQKAQQPSQNPFFDDFFGDLNNFRAFGQLPNTPPTQSGGHNGGGHNGYRPNH
                     TQPAQEANKGLLEEFGINITEMAKRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGE
                     PGVGKTAVVEGLAQKIVDGDVPQKLQSKQVIRLDVVSLVQGTGIRGQFEERMQKLMEE
                     IRKRHDVILFIDEIHEIVGAGAVGDGSMDAGNILKPALARGELQLVGATTLNEYRIIE
                     KDAALERRMQPVKVDEPSVEETITILKGIQPKYEDYHHVKYSQSAIEAAANLSNRYIQ
                     DRFLPDKAIDLLDEAGSKMNLTLNFVDPKDIDKRLIEAENLKTQATRDEDYERAAYFR
                     DQIAKYKEMQAQKLDEQDIPIITDKTIEAIVEQKTNIPVGDLKEKEQSQLVNLAADLK
                     KHVIGQDDAVDKIAKAIRRNRVGLGAPNRPIGSFLFVGPTGVGKTELSKQLAIELFGS
                     ADNMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEQVRRNPYSLILLDEIEKAH
                     PDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNS
                     VLGELSHFFSPEFMNRFDGIIEFQPLSKDNLLHIVHLMLDDVNHRLAHNNIRLDVTQK
                     VKEKLVELGYDPKMGARPLRRTIQDYIEDAITDFYLEHPAEKDMRAVLTSNGHIIIKP
                     VVKSQAKQAD"
     gene            28790..29020
                     /locus_tag="TV188_000207"
     CDS             28790..29020
                     /locus_tag="TV188_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1797 family protein"
                     /protein_id="HEL1533605.1"
                     /translation="MESHLVRIINRLELMVTDGGNLKRNFERDGVVVAEVAFVNDPEN
                     GPVFILRDIEARESYSFDSIDLIAMEIYDLLY"
     gene            complement(29502..30440)
                     /locus_tag="TV188_000208"
     CDS             complement(29502..30440)
                     /locus_tag="TV188_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1533606.1"
                     /translation="MKKTIRKYSVCSAAIALATMASLGTAGNARAEDYTRLESYPDPA
                     ELIRDGLGDGEVRVYLHTLRQFMQTYLQNLELQAKKGGPQGPVGPAGPRGERGEQGPV
                     GPMGPRGDKGETGETGPKGEQGPAGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQG
                     QRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGEQGQRGEKGEQKPKGDQGKDTKPSAPKAPEKTPAPKAPEKSAQPKAPAPKSAPAAQ
                     KSTLPATGETNHPFFTLAALSVITSAGVLNLKKKKS"
     gene            30782..31465
                     /locus_tag="TV188_000209"
     CDS             30782..31465
                     /locus_tag="TV188_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1533607.1"
                     /translation="MDFTFLPKYWAYFNYGVLVTMMISACVVFFGTIIGLLVTLIKRS
                     HIKPLSWLVSLYVWIFRGTPMVVQIMIAFAWLHFNDLPIVGFGVLDLDFSRLLPGIII
                     ISLNSGAYISEIVRAGIEAVPKGQLEAAYSLGIRPKNAMRYVILPQAFKNILPALGNE
                     LITIIKDSALLQTIGVMELWNGAQSVVTATYLPITPLLFAAFYYLMITTILSQLLGCL
                     ERKLAQGGR"
     gene            31467..32204
                     /locus_tag="TV188_000210"
     CDS             31467..32204
                     /locus_tag="TV188_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1533608.1"
                     /translation="MTETVISIRQLHKSFGKHEVLKGIDLTINQGEVVVIIGPSGSGK
                     STLLRTMNLLEVPTKGHISFEGVDITDKANDIFKMREKMGMVFQQFNLFPNMTVLENI
                     TLSPIKTKGMSRAGAEQRAYELLERVGLRDKAAAYPASLSGGQQQRIAIARGLAMDPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAKEVADRVIFMDGGLV
                     IEEGSPVQVFEAPKEERTKDFLSKVLS"
     gene            32648..34342
                     /locus_tag="TV188_000211"
     CDS             32648..34342
                     /locus_tag="TV188_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1533609.1"
                     /translation="MDYKAVYQEWLHNDFFNEEIKADLEAIKHDEAEIQDRFYKVLEF
                     GTAGLRGKLGAGTNRMNIYMVGKAAQALANTIIDHGPEAVSRGIAISYDVRYKSKEFA
                     ELTCSIMAANGIKSYIYKGIRPTPMCSYAIRALNCISGVMITASHNPQAYNGYKAYWE
                     EGSQILDDIANQIAVHMDAIERFEDVKQIPFEEALASGLTSYIDDSIEEAYKKEVLGL
                     TINDTDIDKSVRVVYTPLNGVGNLPVREVLKRRGFDHVFVVPEQEMPDPDFTTVGYPN
                     PEVPKAFAYSERLGQEVGAAILIATDPDCDRVALEVRAADGSYVFLNGNKIGALLSYY
                     IFSQRHARHNLPDNPVLVKSIVTGDLSKAIAAKYDVETVETLTGFKNICGKANDYDIT
                     KEKTYVFGYEESIGFCYGTFVRDKDAVSASMMVVEMAAYYKQRGQSLLDVLQDIYKEF
                     GYYNERQVALELEGVEGQKRIARIMEDFRNEPIEHAGAMSLKTIVDFKDGYLDFPKQN
                     CLKYYFDDGSWYALRPSGTEPKIKLYIYTIGETEADSIAKLDAIESACQAKMDSVS"
     gene            34454..35308
                     /locus_tag="TV188_000212"
     CDS             34454..35308
                     /locus_tag="TV188_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEL1533610.1"
                     /translation="MVQIIDGKALAQKMQAALAKKVESLKAEKGIVPGLVVILVGDNP
                     ASQVYVRNKERAALAAGFKSETVRLSDSVCQEELIELIEQYNQDDTIHGILVQLPLPH
                     HINDKSIILAIDPKKDVDGFHPMNTGHLWSGRPNMVPCTPAGIMEMFHDYGIELEGKN
                     AVIVGRSNIVGKPMAQLLLDKNATVTLTHSRTRRLADICRRADILIVAIGQGHFITKE
                     FVKEGAVVIDVGMNRDVNGRLIGDVAFDEVSELASMITPVPGGVGPMTITMLLEQTYQ
                     AALRRVSQ"
     gene            35305..36159
                     /locus_tag="TV188_000213"
     CDS             35305..36159
                     /locus_tag="TV188_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEL1533611.1"
                     /translation="MIIDQSFVARVVVPRQADSHKGSYGRVLLVGGLYPYGGAIIMVA
                     LACVHSGAGLVTVATDRETIAALHSHLPEAMAIAVDDEELLLSQLGMADLILIGPGLS
                     ENSRAARLFELVLAHVADHQVLVIDGSALRLLAKRAADVKQLRCPLVLTPHQKEWEAL
                     SGLAIDQQYDAANQAALKHFPRATILVAKSSATKIYHGNQIYRLRVGGPYQATGGMGD
                     TLAGMIAGIAVQFPESSLVAKVACATYLHSAIADELAKTAYVVLPTAISYELPRWLKA
                     ISTGQKLG"
     gene            36443..37783
                     /locus_tag="TV188_000214"
     CDS             36443..37783
                     /locus_tag="TV188_000214"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEL1533612.1"
                     /translation="MADYLSVTQLTKYLKLKFDRDPYLERVYLTGQVSNFRKRPNHQY
                     FSLKDEGAVIQATMWAGAYKKLGFDLEEGMKLNVVGRIQLYEPNGSYSMIIEKAEPDG
                     IGALALQFEQLRQKLAGEGFFDERHKQALPQFVTKVGIVTSPSGAVIRDIITTISRRF
                     PGVSILLFPTKVQGEGAAQEVAANITKANQREDLDLLIVGRGGGSIEDLWAFNEEIVV
                     QAIFESRLPVISSVGHETDTTLADFVADRRAATPTAAAELATPITKTDIVSWIAEQQS
                     RSYQACLRYIRQGQERVDKLSYSVIFRQPERLYDAYSQRLDRLTTSLMTTFKETLSGA
                     KQEHLILEHRLASVNVQARLERYQDRLATAHRLLIANMTNQYDSKLAGFERAQAALLS
                     LDTSRIIARGYALLKKDGVVAACVKDIKKGDHLSIIMRDGQLEVEVEDVNEKNI"
     gene            37761..37976
                     /locus_tag="TV188_000215"
     CDS             37761..37976
                     /locus_tag="TV188_000215"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEL1533613.1"
                     /translation="MSTKKIFEERLQELEAIVTRLENGDVPLEEAISEFQKGMVLSKD
                     LQKTLQAAEKTLVKVMQADGTELEMDA"
     gene            37976..38845
                     /locus_tag="TV188_000216"
     CDS             37976..38845
                     /locus_tag="TV188_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEL1533614.1"
                     /translation="MDKLTRINATIHQYYDRQSTVSADLEEAILYSVDGGGKRLRPLM
                     LLELLEGFGLALTDAHYAVAAAVEMIHTGSLIHDDLPAMDNDDYRRGRLTSHKQFNEA
                     TAILAGDSLFLDPFALIAGADLPADLLVQLIQQFSLASGTFGMVGGQLLDMKGEHQLL
                     DIQELSDIHANKTGKLLTLPFVAAGIIAEQSADVLSCLWEAGRLVGQAFQIRDDILDL
                     TASFADLGKTPQKDLAAAKSTYPSLLGLERSRAILEESLSQALAIFSRLEREEGFESQ
                     AIIKRIEGLRLNG"
     gene            38838..39665
                     /locus_tag="TV188_000217"
     CDS             38838..39665
                     /locus_tag="TV188_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEL1533615.1"
                     /translation="MAKERVDVLAYRQGLFETREQAKRGVMAGLVISAISGLRFDKPG
                     EKIDEGIELRLKGEKLKYVSRGGLKLEKALQVFGISVQDKVTIDIGASTGGFTDVMLQ
                     AGARLVYAVDVGTNQLVWKLRQDSRVRSMEQYNFRYAKLADFSEGQPAFASIDVSFIS
                     LSLILPTLHCILQEGAEAVALIKPQFEAGREQIGKKGIVKDRLIHEKVIKQVADTALN
                     CGFIVKGLDFSPIQGGHGNIEFLAHLVKGKGSKAIDDQLIQSVVSSAHKEFKQHEKE"
     gene            39652..40122
                     /locus_tag="TV188_000218"
     CDS             39652..40122
                     /locus_tag="TV188_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1533616.1"
                     /translation="MKKSERLDLIKKMVLSHEIETQHELLKLLADYGLELTQATISRD
                     MNEIGIVKIPSGTGRYVYGLSQDSGKRVVQRPASIKKTILEMSEKTAGLEQHIHLNVV
                     PGNSKLIKRYLMTDFSGQLFSLIADDDSLLLIAKSEADADHIRQELSLWMQGLV"
     gene            40140..41801
                     /gene="recN"
                     /locus_tag="TV188_000219"
     CDS             40140..41801
                     /gene="recN"
                     /locus_tag="TV188_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEL1533617.1"
                     /translation="MLLEISIKNFAIIEEISLNFENGMTVLTGETGAGKSIIIDAMNM
                     LLGARASTEVIRHGADKAEIEGFFSVDANPHLAAVLAESGISMEEELILRRDIFANGR
                     SVSRINGQMVTVSTLKKLGQFLVDIHGQHDQEELMRPQLHQHILDSFGDEAFDQLKQS
                     YQQIFDRYKALRRQALEKQKNEKEHQARLDLLAFQIGEIEAADLVRGEDDLLNQERQR
                     LLNHKKIADTLTSAYLSLDNEDFSSLSQVRSSMNELLSIEDLAPEYQLISAGVSEAYY
                     ILEEVTKQLSDTIDQLDFDAGRLQDIELRLDSINSLTRKYGGGVNDVLDYYANITKEY
                     QLLSGDDRSSDELERELKVLEKQLVMTASQLSDKRHALALELEADIKAELRELYMEKA
                     DFKVHFTRSKFNREGNESLEFYISTNPGEGFKPLVKVASGGELSRLMLAIKAAISKKE
                     DKTSIVFDEVDTGVSGRVAQAIAKKIYKIGSYGQVLAISHLPQVIAIADNQYFISKES
                     KEESTVSKAKLLTQEERIEEIAKMIAGADVTETARNQARELLGKD"
     gene            42022..42894
                     /locus_tag="TV188_000220"
     CDS             42022..42894
                     /locus_tag="TV188_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1533618.1"
                     /translation="MLKKRMGLASLLVLMTFVYQCCSVTAEQYSDTEVEVLQISEEKS
                     QIMENQEALKDLTTSSDQLKKEALKPKEAATNKSKQEASTVYLAEDDPVTIDSSDEES
                     NQDIIADSVPDLVIKGDQVDVSEVMVSVKEDSSKVAKQRTDAAQRYSIAKHQLTQKLE
                     AFNAATDQLLTMIAKKSDLTGQYYVVGHSLGEMLAAQNEKKLAEQLVMQQKHKKGLGS
                     SVTILDELGRVISDISGHKGMLPFNRKISFKVHQVRYDLPLTGDRTVLPAQLAGLLLL
                     LIGLMLPKVANKKS"
     gene            43032..43883
                     /locus_tag="TV188_000221"
     CDS             43032..43883
                     /locus_tag="TV188_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1533619.1"
                     /translation="MELKMGTIKIVADSSMTIEPELIKSLDITVVPLSVMIDSKLYSD
                     NELKEEGQFLQLMRASKSLPKTSQPPVGLFADIYERLVKEGATAIVAIHLSPALSGTI
                     EASRQGAEIAAAPVTVLDSGFTDQALKFQVVEAARLAQAGASLEEILEAVEDIKRKTE
                     LYIGVSALEHLVKGGRIGRVTGLLSSLLNIRVVMEMKNDTLQTLVKGRGNKTFTKWLD
                     SYLAENSQRQIAEVAISYAGQRDFADSLKKTIATVFDGPITVLETGSIIQTHTGEGAF
                     AVMVRYE"
     gene            43876..44718
                     /locus_tag="TV188_000222"
     CDS             43876..44718
                     /locus_tag="TV188_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HEL1533620.1"
                     /translation="MNKRGFLGGLIFFFSVFALSFVILAVLIPKSDPQLKKSDFLKNK
                     KISLNYIAIGDSLTEGVGDLTNQGGFVPLLSGDLGDYFNATVNTENYGVSGNTSQQIL
                     TRMTENKEITEQLKKANLMTLTVGGNDVLAVIRKNLANLKVSSFKKPARQYQERLRKI
                     LDLARKDNQDLPIFVLGIYNPFYLNFQELTEMQTVINDWNKKTQEVVDDYDHVYFVPI
                     NDLLYKGVDGKEGIVQSTGEQTTIVNDALFSGDHFHPNNTGYQIMSDAVMETIRKNGK
                     EIKP"
     gene            44696..45283
                     /locus_tag="TV188_000223"
     CDS             44696..45283
                     /locus_tag="TV188_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HEL1533621.1"
                     /translation="MEKKLNLNWWKWAFLLLLAFNAAFLAVIGSRIIQIREPKSELIN
                     QKAAKNIKIGTLTTTKEQLNEAVVSYLKDFQTEKMTYKVYATSSTILFEGTYQLLGYE
                     VPLYIYFQPHRLTNGAIQLQVLSFSVGTLSLPEKDVLQYLKSSYKLPKFVEVLPKQSA
                     IIINLQQLENDANIYLKAQKIDLVKDDIRFDIYKK"
     gene            45381..45656
                     /locus_tag="TV188_000224"
     CDS             45381..45656
                     /locus_tag="TV188_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEL1533622.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVDAVFSAIEAFLAEGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIAASKVPAFKAGKALKDAVK"
     gene            complement(45717..46421)
                     /locus_tag="TV188_000225"
     CDS             complement(45717..46421)
                     /locus_tag="TV188_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosyltransferase"
                     /protein_id="HEL1533623.1"
                     /translation="MLVVQPSTIKAQSYDEGQTVVFEPYGNSFKPYYKFSEPDVTKYI
                     ITNRWRSQTAFTEAEKKMMYQYTYASASPINLALEQVMGDTSQLDAQLQQSVALLDSA
                     THKLTIPWNIIVYRYVYETFLTELGTSEEELARYYHDKTFDPQILSAIKPGTHYTKQG
                     FMSTTAIKNAAMPHRSVELRIQVPQGSQAAFVQPYSFYPYEMELLFPRQCTLEIIGAN
                     LSDDHTRLLIETRLLP"
     gene            complement(46732..47940)
                     /locus_tag="TV188_000226"
     CDS             complement(46732..47940)
                     /locus_tag="TV188_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1533624.1"
                     /translation="MRKNDYQLLASRAINKIGNTVYDYSNSSGIAGLGATGRQYLGYY
                     QLAEGLISLILNPIGGAIADRYKRRQLLLWTDAIGAISCGLLALIANPTIMLYGLITV
                     NALLAISYAFSGTAFRAYVVTLVETERLVHFNAQLEIVSQIISISSPMLAFLVMDCFG
                     IKTALALDSISFLLSFLCLYTIKDKERHITKQSSQGNRLQLLTDIKEGLQFIYHDNDI
                     FSLLIIASLVNFFIAAFNYLIPFSNQLLGSQSSYASLLSMGALGAILGAFMANKLFKN
                     NQQSLLLSLGLSGLGMLLITAMALLKLPVIVIALGNLWFECFLTIFNIHFFSIVQKKV
                     PEALLGRVFSSIVTTAILLMPLATTIMTCIPASVHLATFAVIGIGIMATASLAYYCNY
                     RQSSKKKPFI"
     gene            complement(47995..48888)
                     /locus_tag="TV188_000227"
     CDS             complement(47995..48888)
                     /locus_tag="TV188_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1533625.1"
                     /translation="MTNHQLGKAFRSIRQNRNITLQQLASKDVSLSQLSRFERGESDL
                     SVTKFLTALDSMQVEISEFMDIAANFKQTEQIQFMSQLIKLEYARDIEGFKQLQKQEL
                     AKHQADPDTNRYYLNSILLQGFICKCNPSIPFPKAYLDEVTDYLFRTESWHIYELILI
                     GNLYLFIDIPLLDKMGKEILNNHTYYESISTNKHLVTITLLNIWETCIHRHQLDYARY
                     YQKQILALLNNETKLYEKTIFLFLKGLEDYQRGQCLSGIKDMTTAISIFESLDCPHLA
                     HNYQKDFERFVASSSLICKKT"
     gene            49257..49430
                     /locus_tag="TV188_000228"
     CDS             49257..49430
                     /locus_tag="TV188_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533626.1"
                     /translation="MPIIVILGLAIFSVVKVIIFLCFYKAFEKKQLKKLEQDQKETKQ
                     AIDQEESKKAFPF"
     gene            complement(49475..50410)
                     /locus_tag="TV188_000229"
     CDS             complement(49475..50410)
                     /locus_tag="TV188_000229"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEL1533627.1"
                     /translation="MVSTATKIATFAFNNCLMNAAGVYCMTKEELLAIEASEAGSFVT
                     KTGTLAPRQGNPEPRYADTALGSINSMGLPNHGYQYYLDIVTEMQKDQASKHHFLSVV
                     GMSAEETETILKAIQASDYQGLVELNLSCPNVPGKPQLAYDFEATDQLLKKIFSYYTK
                     PLGIKLPPYFDIVHFDQAAAIFNQYPLAFANCVNSIGNGLVIDDEQVVIKPKNGFGGI
                     GGDYIKPTALANVHAFYQRLNSSIQIIGTGGVKTGRDAFEHILCGAAMVQIGTALHQE
                     GPAIFKRITKELQDIMAEKGYQTLDDFRGQLQYKP"
     gene            50653..51348
                     /locus_tag="TV188_000230"
     CDS             50653..51348
                     /locus_tag="TV188_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003084158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1533628.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIAFDLAFTSVLKRAIKTTNLALEYSDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPDMAKDDEHSAHTDRRYAHLDHSVIPDAENLKVTLERAL
                     PFWEDKIAPALVDGKNVFVGAHGNSIRALVKHIKQLSDDEIMNVEIPNFPPLVFEFDD
                     KLNLTAEYYLGGE"
     gene            51457..51978
                     /locus_tag="TV188_000231"
     CDS             51457..51978
                     /locus_tag="TV188_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEL1533629.1"
                     /translation="MKVKERREAITDRLSQAQEAISATSLAKALGVSRQVIVGDIALL
                     RAQQLDIISTPKGYILSNALFSHHYSARIVCQHGPEQTRQELELILAHDGIVTNVEVE
                     HPIYGMLTAPLNIKSSADINNFIEKLGASKAELLSSLTEGLHTHLLSCPDQEAFEEIK
                     RDLAAAGILYGEQ"
     gene            52373..52912
                     /locus_tag="TV188_000232"
     CDS             52373..52912
                     /locus_tag="TV188_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533630.1"
                     /translation="MTKKPTQLIAYSSILVAFAILIPMIMPIKLIIGPASFTLASHLP
                     LFLAIFISIPVAILVGIGTGLGFLLAGFPMIIVMRAFSHVLFAAIAAFMLKRQPKWLE
                     TPLRTFVFGIIANVIHGLAEFLVVYLMTATAATDLSYFWSMLMLVGFGSLLHGMVDFY
                     LALFIWRFLRQKGHLSVTS"
     gene            53051..53821
                     /locus_tag="TV188_000233"
     CDS             53051..53821
                     /locus_tag="TV188_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEL1533631.1"
                     /translation="MKTPEQILAATITIGEHKVAKPFLAKAILGFIGGAMISLGYLLY
                     VRIAASGLETFGAFSSILGACAFPIGLIIILMAGGELITGNMMAVSAAFFAKKIKAKD
                     LMANWLVITLFNILGALFVAFVFGHFLGLTATGSFKEEVIEVAHAKLAATPLQAIVSG
                     IGCNWFVGLALWLCYGASDATGKLLGTWFPVMTFVALGFQHSVANAFVIPAAIFEGGA
                     SWIDFATNFALVYVGNVLGGAIFVSLFYYKAYDHSKEA"
     gene            53933..55987
                     /locus_tag="TV188_000234"
     CDS             53933..55987
                     /locus_tag="TV188_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HEL1533632.1"
                     /translation="MASWIKKKKASIPRRIHLLFLVIVFLFVALILRLAQMQIYEKDF
                     YKAKLTASTVYKVKSSMPRGTIFDRNGKVLVSNRIKDVVTYTRSPKASAKDIKALAHQ
                     LAAYISYPEAKVTVRAKKDYYLADPEAYAKTVQALPQKDKVDRFGNKLVEAQIYQNAA
                     ASLKETDLTYSDQELKVIAIFNQMNAAAVFSTVKLKTSALSEQDIAIIMANKSKLPGI
                     SVGTDWERQVEETSLAAIIGRVSSEEAGLPKEEAKAYLKKGYSLNDRVGTSYLEKQYE
                     EVLQGKHEIREIKTSRSGEVISDKIVEKGQMGRNLKLSVPLDFQQGVEQILNQHFQTE
                     LKNGQAAYSEGIYAVALNPNTGAILAMAGLSHNPKTGELQKDALGTITDVFTPGSVVK
                     GATLAAGWQAGVIQGNQVLIDQPIQFGGSQPINSWFTSGQHPITASQALEYSSNTYMV
                     QVALRMMGQDYVTGMTLANTGMKETMKKLRAAYAEFGMGVATGVDLPGESSGYLIDQY
                     NTANVLTEAFGQFDNYTTMQLAQYVSTIANGGSRLAPHIVEGIYQDNDQSGPGKLSKA
                     IETTLLNKVHLAADSLAIIQDGFYQVVNSGSGYATGRALAGGPVTISAKTGTAETYAK
                     DKNGQALSTFNLNVVAYGPSASPQIAVAVMYPHATDSLAKAHQYVAKDIINLYMKMYK
                     NQ"
     gene            55999..56595
                     /gene="recR"
                     /locus_tag="TV188_000235"
     CDS             55999..56595
                     /gene="recR"
                     /locus_tag="TV188_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEL1533633.1"
                     /translation="MLYPIPIAKLIESYSKLPGIGVKTATRLAFYTIGMSDEDVNDFA
                     KNLLAAKRELTYCSICGNLTDDDPCHICTDSSRDKEIILVVEDSKDVSAMEKIQEYHG
                     YYHVLHGLISPMNGVGPDDINLKSLITRLMAGEATEVIVATNATADGEATAMYISRLL
                     KPAGIKVTRLARGLAVGSDIEYADEVTLLRAIENRTEL"
     gene            56743..57789
                     /locus_tag="TV188_000236"
     CDS             56743..57789
                     /locus_tag="TV188_000236"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEL1533634.1"
                     /translation="MSKQTLILLYGGRSAEREVSVLSAESVMRAVDYTKFFVKTYFIS
                     QTGQFIKTQEFSSRPTLTERLMTNDTIRLEQQIRPSDIYEEGAVVFPVLHGPMGEDGS
                     IQGFLEVLKMPYVGTNILSSSVAMDKITTKRVLESAGIPQVAYTVYIEGQDLDRCLAE
                     TEAVLSYPVFVKPANMGSSVGISKAESEEELRAAILLALTYDSRILIEQGVLAREIEV
                     GLLGNTDVKSTLPGEVVKNVDFYDYQAKYIDNEITMAIPAAIDESAMTSMRTYAETAF
                     KAIGACGLSRCDFFLGQDGQIYLNELNTMPGFTQWSMYPLLWEHMGLSYAELIEELVR
                     LAQEMFEKREGHLI"
BASE COUNT        16183 a        10891 c        14089 g        16818 t
ORIGIN      
        1 tactcatgat tagaatggta aaaaataaag gtgacttagt cgcgaaaatg atttaaagga
       61 ggagctatga aaaaaagctt tattcatcaa caagaggaaa tttcctttgt taaaaataca
      121 tttacgcagt atttgattgc taagcttgat gttgttgagg tgcaaggtcc tattttaagt
      181 agggtcggag acggcatgca ggacaattta tctggggttg aaaatccggt atctgtccat
      241 gtcttgaaca ttcctaatgc aacctttgag gtggtgcatt cgctagcaaa atggaagcgt
      301 cataccttag cacgttttgg ctttaatgaa ggtgaaggtc ttgtggtgaa tatgaaagcg
      361 ctccgtcctg atgaagattc gctagaccag acgcattcag tgtatgtgga ccagtgggat
      421 tgggagaagg ttatccctga tggtcagcgc aatctagctt acctcaaaga aactgtcgaa
      481 acgatttaca aggttatccg cttgacagag ctagctgttg aggcacgcta tgatattgaa
      541 gctgtcttgc caaagaaaat taccttcatt cacaccgagg agcttgttgc cagataccct
      601 gatttgacac caaaggagcg tgaaaatgct atcacaaaag aatttgatgc ggtatttttg
      661 attggtattg gcggtgtatt gccagatggc aagccacatg acggtcgtgc gccagactat
      721 gatgactgga ccagtgagtc agaaaatggc taccatggct taaatggtga tattctcgtt
      781 tggaatgagc agctaggcac agcctttgag ctattctcaa tgggaattcg tgttgatgaa
      841 gaggctctaa agcgtcaggt ggacattact ggagatcagg aacgcctaca atttgattgg
      901 cacaaatcgc tgctaaatgg tctgttcccc ctaaccatcg gtggaggaat tggtcaatcg
      961 cgtatggcca tgtttttgct tcgtaaaaag cacattggag aggtccaaac atcggtgtgg
     1021 ccacaagagg ttcgcgatac ctacgacaat attttataga tgatacggag gctaggtttt
     1081 tacctatagc ctctattttt gtccctaagt gatgcttcat tagagctcat ttagtgctaa
     1141 gcaggctcgt cagttatata ataggtcaaa aatttgaaaa aatgaatcat ttttaaggct
     1201 tgacactaga tttttgttat aatatcagtt atgagaattg tatcaggtga atttggaggg
     1261 cgtcccctaa aaacgctcga aggcaagact actcgaccca catcagataa ggtacgtggc
     1321 gcgattttta atatgattgg tccttatttt aagggcggac gtgtcttaga cttgtttgct
     1381 ggatcaggtg gcctatcaat agaggctatt tctaggggca tgtcagaggc agtgctggtt
     1441 gagcgtgatc gtaaggcgca agccattatc caagccaata ttaagatgac aaaagctagc
     1501 cagcaattta cgctattaaa aatgaacgct gagcgtgcac ttgatcactt atccggtcag
     1561 tttgatgtgg tgtttttgga cccaccttat gctaaggaaa cgatagtagc caatatagag
     1621 gccttggtgg agaaaaatct tttaagcgac gatgtgatga ttgtttgtga gacggatcgg
     1681 tcggtagctc tgccagaggc aattgcctgg ctagggatct ggaaagaaaa acaatatgga
     1741 attagcaagg taacagtata tgtcaggtaa gattggactt tatacagggt catttgaccc
     1801 agtgacaaat ggacacatgg atatgattaa gcgtgctagc catttgtttg agcatgttta
     1861 tgtcgggatt tttaacaatc caaataagca gagctttttt acttttgagc tgcgagctca
     1921 aatgctaagc gaagcggttt gtgccttgcc aaatgtgaca gtggtttctg ccgagcatgg
     1981 tcttgcagtt gacctggcta gggagctgtc tgtgacccac cttatccgag ggcttcgcaa
     2041 tacagctgat tttgactatg agataggctt agagtatttt aatcatagac tagcccctga
     2101 tattgagacc atttacctga tggcgactca tgacctgcag cccgttagct ccagtcgtat
     2161 cagagagttg attgcattta gagcgccaat tactggtttg gttccgcagg ctgttattaa
     2221 tcaagtggag aaaatgaatg aaaacaataa aaaaaattaa atggtggctg attggctttg
     2281 ttgccttgct ttttctactg ttgacactgt ttttcccctt gccttattat attgaaatgc
     2341 caggtggagc ctatgatatt cgctcggtat tgactgtcaa tggcaaagag gataaggaaa
     2401 agggagctta tcagtttgtt gtagtgagcc tcagtcgggc caccttggct aaattgctct
     2461 atgcttggct aacgcctttc actgagatta gcaccatgga agatactact ggtggctata
     2521 gcgatgctga ctacctgcga attaatcgct tttatatgga aacctctcaa aacagcgctg
     2581 tttatcaggc ccttactcta gcaggcaagg aggtaagctt tgattataag ggtgtttatg
     2641 tcttagacgt cagcaaggat tctagcttta aaggtgtgct gcacctagca gatacagtga
     2701 caggtgtcaa tggtaaaaca tttacaacgt ctgccgatct gattgattat gtttctcatt
     2761 tgaccttggg agatgaggtg caggtacaat ttacaaccgc tggtgagtca aagactgaaa
     2821 aaggaaagat tattaagctt aaaaacggta aaaatgggat tggcattacc ctgacagacc
     2881 acacacaggt catttctggt gatgaggtcg actttagcac tggaggtgtg ggtggaccaa
     2941 gtgcaggctt gatgtttact cttgatattt atgatcaaat caatcacgaa gacttgcgca
     3001 agggacgtgt gattgctggt acaggaacca ttggcaagga tggaaaagtt ggagatattg
     3061 gcggggcggg cctaaaggtg gctgccgccg ccgctgctgg tgctgatatt ttctttgttc
     3121 caaataatcc tgtgcataag gacgtcaaaa aagcaaatcc taaggctatt agcaattacg
     3181 aggaggctaa aaaagcagct aaacgactaa agacagcaat gaaaattatt cctgtgaaaa
     3241 ccgttcaaga tgctataagc taccttaaaa aatagaagca atgcgaagca ggctaatagg
     3301 gcatgctctg tcttgcttct agttggtgga atttagctag ctcaaaggtc ttgagaccta
     3361 agcataaggt ctagacagta ttctagagct agaccttatg cttgatcctg aacaaggaag
     3421 accgccaaag aagaacaaaa tcctcaggcc aaaagagccc gtagggaaat attgccatta
     3481 tctatcaagg ctttttgaag aaaatcactt aaagacagta gggcgttagg ctttactgtc
     3541 ttagtttttc ttgcctgaag tcatggctgc tgatgatgtt acatcaaggc ttactagcca
     3601 gcagagcaca aggagcagct ttggcttagg tttattttct ctgctgacta gtaaagaagg
     3661 ttgctgtcag tctgcttaca aaaacctaaa aatagtgtat aataggtagg ctatgggctg
     3721 tcaggagtcg ctagcctgct tacccagacc agccctttga gaagagcaag catggctctt
     3781 ctcagaataa cccaggatta acagacatca aaattaatgc taaggaaagg agctatatga
     3841 aaagagatat tttaccagag atgtataatt acaataaatt tcccggtccg gaatttattc
     3901 attttgatca ttatgtcaag gctgaaggca ttgagttatt gctgctgaaa aatgaaaaaa
     3961 atgcttttaa cacaacgagc tttggtcagc gcttcacaga gatattatta aagtatgact
     4021 atattgttgg agattggggc aatgaacagc tgcgtctcaa gggcttttac aaggatcatc
     4081 atgatgtcaa aaaagctagt cgtatttctc gcctagaaga ctatattaaa gaattttgta
     4141 actttggctg tgcctatttt gttttggaaa accctaatcc caaggacatg ccaaaagagg
     4201 aggaaaggcc atcaaggcgc aggaaatcgt ctaaagccaa tcgccgcaga aatcagcctc
     4261 agcatagtca gcaggcacct gctaaagaca acttcaaaaa gctaaccaag gataggtcag
     4321 cggacaagcc aagctttacc agcaaaaagc gcccagctcc taataagacc aagggaaacc
     4381 aaaggcgctc tcgtactagt caactgaacc ataaaacgga tcactttatc atcagaaaga
     4441 aggacaatta atctatgaaa ccatcaatct atggcctaac gcgcgacgag ctaattgctt
     4501 gggcgattga caatggtcaa aaggcattca gagcgacaca gatttgggac tggctttaca
     4561 gaaaacgggt tcaatccttt gatgaaatga ctaacatttc taaggaattt gttgccattc
     4621 taaaggacag cttttgtatt aatcccttga agcagcgtgt tgctcaggaa tcagctgatg
     4681 gaacggttaa gtatttgttt gaattgccag atggtatgct gattgaaacg gttttgatgc
     4741 gtcagcacta tgggcagtcg gtctgtgtaa ctacgcaggt tggctgtaat ataggctgca
     4801 ccttctgcgc tagtggcttg attaaaaagc aacgggattt aaacagtggt gaaatcactg
     4861 cacaaattat gatggtgcaa aactattttg ataagcgtgc tcaagacgaa cgtgtcagcc
     4921 atgttgttgt gatggggatt ggagagccct ttgataatta tcaaaatgtg atgacctttc
     4981 ttcggacgat caatgatgat catgggcttg ctattggtgc tcgtcacatt actgtttcaa
     5041 cctcaggctt ggctcacaag attcgtgaat ttgccaatga aggagtccaa gttaatctgg
     5101 ctgtgtcact gcatgcacct aataatgagc tgcgctcaag tatcatgagg atcaatcgtt
     5161 ccttcccact tgataagctc ttttcagcaa tcgaatatta cattgaaaca actaatcgtc
     5221 gtgtgacctt tgagtatatc atgcttaata aggttaatga tggggtagag caggcacagg
     5281 aattggcaga tttgaccaaa aggattcgca agctgtctta tgttaacctg attccctata
     5341 atcctgtctc agagcatgac caatacagta gaagtcctaa ggagcgtgtg gcagcctttt
     5401 atgacattct aaagaaaaat ggagtgaact gtgtcgttcg tcaggagcat ggtacagata
     5461 ttgatgctgc ctgcggtcag ctgcgctcta ataccatgaa aaaggaccga caaaaagcag
     5521 cagctgcaag gacatgatga cttggtcaag gttgctgatt tgattgatag gagatggaga
     5581 taaaaatctg acctcaaata aagcaaacaa ataggtctag ttttctgaga tcccgaaagc
     5641 aggtcttgtt cgttttttaa tgaatgagac taggtcataa agtacatgcg ttaagaatgt
     5701 ctaaagtgca gctctttttg tcccagcctc cctcttttat cttggtagca gttgtcaagt
     5761 aattgctaag caacagtgtt ttatctttat tggctgtaaa aaaagatata gtgcctttat
     5821 tcacaccttt tctgaatcac ttgagccttg ttctgaccgc tccttttggt gcttctgatc
     5881 catatagcct aagcttttca gagctatgaa tcgaggcaaa ataataggtg ttagccctag
     5941 ctgcttgatg tagctagggc ttttgtgacc tagctgccag tgagcctttc aaatagcaat
     6001 atggctataa ggcccagtgt cagataggga ataaaaggga ttttcttagt ttgtagaagt
     6061 aggcaggcta gaattccgat cagactggca atttggacga tccataacaa agagctaagc
     6121 ttgaccacaa gagcaagatt agctaggtaa agaaaatctc cggcaccaat attgatagga
     6181 aaagctacgc ttagcagtgc aagcaaaagc aatagcactg ttaacaggtt aatgctataa
     6241 aatggcagca gaaacaaaaa gctcatcagc cagatgagca aaggatactc ttgactgtct
     6301 aaatcaaaaa agcacagtag caaagagaag cataggagat aaagctgtgt ccaggtcaag
     6361 ccgcaaaggg cagccagtcc gaaaatgagg ctggtgatta tttctaaata aggaagcata
     6421 acccagtgct tttgttcatg cttagagttg taagtgggct ttgccatagg aaaaaagagg
     6481 cttgaaagat gaagttgacc tatatagagc ttgacccaag cctttgcttg ctgttcagaa
     6541 aacaggttaa gtattagccg aaagaggttt cccacaagaa aaccacaata gcaataaaaa
     6601 atagtgttca tacttattta tccgaaaaac aatttaaatt cttgcaatat tttaaaaaac
     6661 ggtgtacaat gaaactataa aacgagaatg attctaaata agctgttgat acttatctga
     6721 attggctcgt tatcgtcgaa tggagctgac aagagagtga cttttcttgc tgcataccat
     6781 tcatgccctt ttatatctat cagtaaggag agtttattat gacaaacaca ctcgttgaaa
     6841 acatttatgc atcagtaact cataatattt ctaaaaaaga agcatcaaaa aatgaaaaaa
     6901 ccaaggctgt tttaaatcaa gcagtagcag atctatctgt agcagcttca attgttcatc
     6961 aggttcattg gtacatgcgt ggtcctggct ttttatacct gcaccctaag atggatgagc
     7021 tattagaccg cttgaacgcg aacctagatg agatgagtga gcgcttgatt actattggtg
     7081 gggcacccta ctcaacccta gaggagtttt cacagcattc taagctagat gaaacaaagg
     7141 gaagctatga taagtcagta gctcagcatt tagctcgttt ggtagaggtt tacctttacc
     7201 ttaccagtct ttatcaggtt ggtttagaca ttactgatga agagggtgat gctgcttcaa
     7261 atgatttgtt cacagcagca aaggctgacg ctgaaaagac tatttggatg ctacaggcag
     7321 agcgtggtca aggtcctgct attttctaaa gcgtcataca actgatataa cataaaaaag
     7381 gcagagcgtg gtatagccct gtctttttaa cgcctttaaa gtcagctatt agtgctagtg
     7441 atgtcaggtc tcacagcttt tttatgatgg atgaccaaca tttttagacc ttgtcaccac
     7501 agcagagcat gtggcattta gtccaccttg ggctcacgtc gatggtctta cttatgatat
     7561 atcaaggctt gtgacattac cgttgccttt tatcttcagt ctgagctgct ggttcctact
     7621 gctgatgctg cttgatagtg ttatagtgat tttcagaaat atggaaagcg attgcataat
     7681 tgtcttgaaa tctcatgcgt aatttgctaa aatctagtta tatgaaaaca ttatacgatg
     7741 tacagcagct gttaaaaggc tttggtattg ttatctacat gggaaagcgg ctttatgata
     7801 ttgaaatgat gaaaatagag ctgcaaaggc tatatgatgg tggcttgttg gataaacagg
     7861 cttatttaac tgctgagctg attttacgac gtgagcatcg attagagcta aaaagagaag
     7921 ggcaagaaaa tgagtcaaaa attgataggg attgatttgg gcggaaccac gattaaattt
     7981 ggtattttaa cctcagaggg tgacgttcag gaaaaatggg cgattgagac aaatgtttta
     8041 gaggacggta aacatatcgt tccagatatt gtcgcctcac tcaagcatcg ccttgacctt
     8101 tatggactga ctaaggacga ttttatcggt attggtatgg gctcacctgg agctgtcaat
     8161 cgcacagatc atactgttac aggggccttt aacctcaact ggagaggcac ccaagaggtg
     8221 ggatctgtta ttgaaaggga gctaggaatt ccctttgcta ttgataatga cgcaaatgtt
     8281 gcggccctcg gcgagcgctg ggtcggtgca ggtgacaata atcctgatgt ggtctttatg
     8341 accttaggaa caggtgttgg tggtggtatc atcgctgatg ggaacttgat tcatggtgtg
     8401 gctggagctg gtggtgagat tgggcacatg atagtagagc cgcttaaggg ctttgcttgc
     8461 acctgtggct cacagggctg cctggagaca gtggcctctg ctacaggtgt tgttaaggtt
     8521 gctcgtcttt tagcagaagc ctacgaagga gattcaagca ttaaggcagc gattgataat
     8581 ggagaggctg tctcaagcaa ggacattttt gttgcagcgg aggctggtga tgcctttgcc
     8641 aactctgttg ttgaaaaggt cagttattat ctaggactgg cagcggctaa tatctcaaat
     8701 attttgaacc ctgattcggt cgttattggc ggtggtgtat ctgctgcggg tgagttttta
     8761 cgttcacgtg ttgaaaagta ctttatgacc tttacctttc cgcaggttag acagtccact
     8821 aaaatcaaaa tagcagagct tggtaatgat gctggtatta ttggtgcagc tagccttgca
     8881 agacaattta tcacagaata ggagttaatg atgtcaccac ttacaatgat tggctgggta
     8941 ttgcttgcgg gagtgattgc ctattacctt tggaattatg tttcctatag aagaatggca
     9001 aagcaggttg ataatgatac ctttaaggag ctgatgcgtc aggggcaagt gattgacctg
     9061 cgcgatccag cttcctttag ggcaaggcat atcctaggcg ctagaaattt tcctgcccag
     9121 cagtttacta cctctattaa ggctttgaga aaggacaagc caatcttgct ttatgaaaat
     9181 gtaagacctc aatatcgggt caaagcagtc aaaacattac gtaaggctgg ctatacggac
     9241 ctttatgtcc taaaagcggg actagattat tggaatggta aggttaaata gccttatagt
     9301 cctttttgct gagctaacgt ttgctgctat gtgtcggaac gttgcaagca gcagcttatc
     9361 taagcttgtc atgctagttt cacagcccaa agtggctggc cgtataaacg cagctgcttt
     9421 tagatgccgg taggagcttt tgtcagcttc tttagggatt gttttaagtg atgtagagag
     9481 gccgttctga gagaaagcct tgtagttaga aaaagagatg agaaagctaa ggctcttgct
     9541 gctgttgtaa gagttagctt tctttttctt ttttgtgtgg cgcatttaag ggcttgaaaa
     9601 catttacaat tccctcagat cggtttttta aaaaaatttg tgttatactg ttttagttaa
     9661 aactatttat gctacaagag gaaaaaatga caaaatttag agaagatatt cgtaacgttg
     9721 ctattattgc ccacgttgac catgggaaaa caacgctcgt tgatgaatta ctaaagcaat
     9781 cccatacact agatgagcgc aaagagcttc aagaacgtgc gatggattca aatgaccttg
     9841 aaaaagagcg tggtattacc attcttgcta aaaataccgc agtagcttat aacgatgttc
     9901 gtattaatat catggatact cctgggcacg ctgactttgg aggcgaggtt gagcgtatca
     9961 tgaaaatggt tgatggtgtt gtccttgttg ttgacgctta cgagggaacc atgcctcaaa
    10021 cacgctttgt gctgaagaag gccttagaac aaaatttaac cccaatcgtt gtggttaata
    10081 agattgataa gccatcagct cgtccagctg aggttgttga tgaggttctt gagcttttca
    10141 ttgagcttgg tgcagacgat gatcagctgg agttccctgt tgtttacgct tcggcgatca
    10201 atggcacatc ttcgttgtca gatgatcctg ctgatcagga aaaaacaatg gctccgattt
    10261 ttgataccat tatcgatcat attccagcac ctgttgataa ctcagctgag ccccttcaat
    10321 tccaggtgtc acttcttgat tacaatgatt ttgtaggtcg tattgggatc ggtcgtgtct
    10381 ttcgtgggac tgttaaggtt ggagatcagg tgacgctttc aaagcttgat ggcaccacta
    10441 aaaatttccg cgttactaag ctgtttggct tcttcgggct tgagcgcaag gagattcaag
    10501 aggccaaggc tggtgacttg attgcagttt ctggtatgga ggacattttc gttggtgaga
    10561 cgattacacc aacggattgt gtggaggctt tgcctgttct tcgcattgat gagccgacac
    10621 ttcaaatgac cttcttggtt aacaactctc cctttgctgg tcgtgaaggc aaatgggtaa
    10681 cctctcgtaa ggttgaggag cgtttgcttg tggagcttca aacagatgtg tcccttcgtg
    10741 ttgagccaac agaatcacca gataaatgga ttgtgtcagg tcgtggtgag ctgcatctat
    10801 ctattttaat tgagaccatg cgtcgtgagg gctatgagct tcaggtatcg cgtccagagg
    10861 ttatcattaa ggaaattgat ggtgtcaagt gtgagccttt tgaacgtgta cagattgaca
    10921 caccagagga atatcaaggt gctattatcc aatccttgtc agaacgtaag ggggatatgc
    10981 ttgatatgca gatggttggt aatggtcaaa cgcgtcttat ttttctcatt cctgcccgcg
    11041 gcttgattgg ttattcgact gaatttttat caatgacacg tggctatggt atcatgaatc
    11101 atacctttga tcagtatctg ccagtggttg ctggtgagat tggtggacgc catcgtggag
    11161 cgctggtttc gattgaaaac ggtaaggcaa caacctactc aatcatgcgt attgaagagc
    11221 gcggaacaat ctttgttaac ccaggaactg aggtttatga gggcatgatt gttggtgaaa
    11281 attctcgtga caatgacctt ggggttaata tcacaactgc taagcagatg accaacgttc
    11341 gttcagcaac aaaggatcag acagctgtta tcaaaacacc acgtattcta acccttgagg
    11401 aatctcttga attcttgaat gatgacgaat acatggaggt aacgccagaa tcaatccgct
    11461 tgcgcaagca aattttgaac aaagcagcgc gtgataaagc taataaaaag aaaaaatcag
    11521 cagaataaag gctggttggt ctgagcatca cactcccttg ccgctttaac tagtaagcta
    11581 ggttggcaga ggattgaaag gagctttctg tgttttatct tattattgca gccttgatta
    11641 cctcttatta cctgtttatg gcaccaaaga gcgtccgtaa cacactaggt atgattggtt
    11701 tggttggttt ggttgcccta ttgattgtgc tagctggctt aagttttatc aaaatcatgc
    11761 aaacgcccaa ggaaattttc gttggtctag ccatgatagt attgggctac tatgccctaa
    11821 gggacattca aaaaatccct aaaaaaccaa agagtaaaca ttagcatcaa gcattgagtc
    11881 aaatcttaat agggtttgac tttttctgtc tttgtactgg ccttatgcgc tgctatctgt
    11941 aaaatcttga aaaagcagtt aaataagggt aaaatagtag tcaaatagac atagatagtg
    12001 tggataaaaa tgaagacaat aacggaattc caaaataaaa aggtattgat tcttggcctg
    12061 gccaaatcgg gcgaagcagc agctaggctt ttagcccggt tgggagctat tgtgacagtt
    12121 aatgatagca agccctttga ggaaaatccc gcagcacagg ctcttcttga ggagggcata
    12181 agggttattt gtggtagcca ccccttggag ctgttagatg aagactttta ttgtatggtt
    12241 aaaaacccag ggattcgcta tgacaacccg atggtggtac gcgccttaga taaggctatt
    12301 tctattctaa cagaggttga gctggcttat ttggtatctg aagcacctat cattggtatt
    12361 acgggctcaa atggtaaaac cactacaacc acaatgattg ctgatgtgct aaatgctggg
    12421 aaccattcag ctcttttggc tgggaatatc ggctttcctg cttcagaggt ggctcaagct
    12481 gctacagcaa aggatatact ggtcatggaa ttgtcttcct ttcagctgct ggggactgag
    12541 cagtttcagc cacatattgc agtcattact aacctagtgc ctactcatct tgattatcat
    12601 gggagttttg aggactatat agcggccaag tggcgcattc aacatcgaat gaccgataag
    12661 gattaccttg tgttaaatgc tgatcaagag ctggtaaaat cattggctca aaagactaaa
    12721 gcaagtcctg tctttttttc taccaaagaa aaagttgatg gtgcttattt ggcagatggg
    12781 tatctttatt tcaaagagga gaggctgatg tcagcagctg agcttggtgt tcctggaagg
    12841 cataacattg aaaatgctct tgccaccatt gctgttgcaa agctaagagg catttctaat
    12901 caagtgatat caaggacttt gtctcacttt aggggggtga agcaccgcct tcagttagtt
    12961 ggtacattga atcaagtgac cttctacaat gacagcaagt caaccaatat cttggcttgt
    13021 caaaaagcct tgtcgggctt tgataatagc aaggttatcc tgattgctgg tggcttggat
    13081 cgtggcaatg aatttgatga gctggtgcca gacctcgttg gtcttaaaaa gatgattctt
    13141 ttaggggaat ccgcagagcg tatgaagcga gctgcagaca aggcaggagt gtcctatctt
    13201 gatgccaaag atgttgcagc tgccactaaa atagcctttg agcaggcaaa ggctggtgat
    13261 attatcttgc tgagcccagc caatgctagc tgggatatgt atccaagctt tgaaagccgc
    13321 ggcgacgagt ttttagcagc ctatgacgcg ttaaaaggag aggctcaatg accaagaaaa
    13381 tcatttttac cggtggtgga acagctggtc atgtcacttt aaaccttatc ctcataccga
    13441 agtttatcaa agatggctgg gaggttcact atattggtga tgacaaaggc attgagcatc
    13501 aggagatcaa aaagtcaggt cttgatgtca cctttcatgc tattgcaact ggaaaattaa
    13561 ggcgttattt ctcttggcaa aacctgcttg atatcttcaa ggtaggcttt ggtgtcatgc
    13621 aatcactttt tatcatagct agactaaggc ctaaggctct cttttcaaag ggaggctttg
    13681 tgtcggttcc tcctgtgatt gctgcaaggc ttttaggggt gccggccttt attcatgagt
    13741 cggatctttc tatgggcttg gctaatagga ttgcttatcg gtttgcaaca acgatgtata
    13801 caacctttga gcaagagcag acactggcaa agctcaagca tgttggagcg gttaccaagg
    13861 tgacaggtcc tgggagtcga tcggtgactt ctaagcagct tgaagctgtt ttggagtatt
    13921 ttgatcctaa tttaaaaaca cttttgttta ttggaggctc cgcaggggct agggtgttta
    13981 accgctttat cactgaccat cctgagctaa aggaagactt taatatcatc aatatctctg
    14041 gcgatcctag cctaaatgag cttagttggc atctttaccg cgtggattat gtgactgatc
    14101 tgtatcaacc gctcatggaa atggctgatc tggtagtgac tcgcggaggc tctaacacac
    14161 tttttgaatt attagcgatg agaaagctcc agcttattat cccacttggc aaagaggcca
    14221 gtcgaggtga tcagcttgag aatgctcatt attttacaac aaggggctat gctgagcaat
    14281 tattggagca ggaattgacc ctgcctcatt ttcaagagaa agtgagagaa gtctttgcta
    14341 agcaatcgga ctatttatct gcaatgaaga gctctagcga gctccaatca ccagaaagct
    14401 tttaccagct tttaagtgcc gacattagct ccgcgacaaa ggaaaattaa atggcagata
    14461 agacaaaaca ttcagaagaa aaagccgctt tgaccgaatg gcaaaagcgt aatattgaat
    14521 ttctcaacaa gaagcagcag caggctgaga aagacaaaaa actaaaagaa aaattattaa
    14581 atgagaaaat agcgcaagct cagggagagg cagcttcaaa ggctgaccaa gaagatacag
    14641 atgaagctga ggagaaaact gaggtaagcc aagcgggtac tgatgagggt gagccgctgc
    14701 cagaagcatc agagcaggaa gtcccctccc caaaagacaa gccattaaaa gtccccaaag
    14761 aaaaaagtcc aaagcagcag gcacttcaaa agggctggcc tgtattgctg gtgtcgtttg
    14821 tggttttgtg cctgtcgatt tttatgatca caccctatag taaggtcaag gatttctccg
    14881 tcaagggcaa taaaaaaaca agcgttgagg acttagttag agacagtggg atcaagtcat
    14941 ctgattactg gattactcta ttagcctctc cgggttctta tgaaaatgcg gttttaaaag
    15001 ccaatccctg ggtgaaaaag gtggctttgc gttacggctt tcccaatcat ttccgctttg
    15061 atgtgacaga gtttgatatt attgcctacg ctcaggtagc tgaagggttt caactgatcc
    15121 tagaaaatgg caagcgagtt gctgctgtca agcaggctgc tttgcctaaa tcctttttga
    15181 ttttaaatct tgagcatgaa aaagagattc aagatgtcat taatcgcttg accaaaatcc
    15241 caagtgacct agtcaaggct atcaaatcag tgtcatcggc caattcacag acaactaagg
    15301 atttgctgct tcttgaaatg cacgatggca accttatcag ggtacctcgg tcacagcttg
    15361 agctaaagct gccttattac caaaaaatca agaagaatct tgatactgct agcattgttg
    15421 atatggaggt tggtatctat acgaccactg ctgaaattga aaacatgcct gaggtgccag
    15481 cgtctgctca agcttctcag gcagataagc ctgctgaggc ttcaccagag cagggtgaag
    15541 agcaggccac acaggagcag cctagccctg aaacacctgc taatcctgag gccacaaatc
    15601 cctcagtcgc ccagcctact gagcaggcaa atcaacagta atcgtttagg gtaagagaag
    15661 ggggcaaaaa agcatttaag gctcttaaat taggcccttg ttgaacggca aaaaaacatt
    15721 aagtttatat aacaaaaaac gtaaaatggt aacattttac gtttttttat gatataatat
    15781 tccctgaata attctgcttt ttagcagtgt ttttgaatag taaaagtttg gaaagtaagt
    15841 gaggtcgagt gaatggctag aaatggcttt tttactggtt tggacattgg aacaagctcg
    15901 ataaaggttt tggtagcaga gtttatctct ggcgagatga atgttattgg tgtgagcaat
    15961 gttccgagta ctggcgtaaa agatggcata atcattgata tagaggcagc agccgctgct
    16021 attaaaactg cagtagaaca agctgaagaa aaagcaggaa tgacaattga aagggtcaat
    16081 gttgggctgc cagcaaacct ccttcaaatt gagccgacac aaggcatgat tcctgttcct
    16141 agcgaatcaa aagaaatcaa agatgaagac gttgatagcg ttgttaagtc agcactaact
    16201 aagagcatta ctccagagcg agaggtgatt tccttagtcc ctgaagagtt tattgtagac
    16261 ggctttcagg gcattcgaga tcctcgtggc atgatgggga tcaggcttga aatgcgcggt
    16321 ctgatttaca ctggaccaag cacaatcctg cataacttaa gaaagacagt tgagcgtgct
    16381 gggattaagg ttgaaaacat catcatttct cctttggcaa tggctaaggc ggtgttaaat
    16441 gaaggtgaac gtgaatttgg tgctacggtc attgacatgg gtggaggaca aaccaccgtt
    16501 gcctcaatgc gagcacagga attgcagtac accaatatct atgcagaggg tggcgagtat
    16561 atcacaaagg atatctctaa ggttcttaaa acgtcaatgt caattgcaga ggccttgaag
    16621 tacaattttg ggcaggctga tatggcagag gcaagcttga ctgacactgt taaggttgat
    16681 gttgttggca gtgatgagcc agttgaggta acagagcgtt acttatcaga gattatctcg
    16741 gctcgtgttc gccatattct agatcgtgtt aagcaggatt tagaaagagg acgcctgctt
    16801 gatttacctg gtggcattgt gctgataggt ggcggcgcca ttatgccggg cgtggttgag
    16861 gttgctcaag agatttttgg aaccaatgtt aagcttcata ttccaaatca ggttggtatt
    16921 cgtaacccaa tgtttgccaa tgtcattagc ttggtcgagt acgttggtat gatgtcagag
    16981 gtggacgttt tagcgcaaaa tgctgtatca ggcgaggaat tgctaagacg taagccgatc
    17041 gactttactg gccaagaagc ttacttgcca gactacaatg agactagggg atttgaaccg
    17101 gctcctaatt atgagcagca agtgccccaa gcagactacg agcctcaaga acccgctgaa
    17161 ccaaagcaaa agatttcaga gcgtgttcgt ggcatttttg gaagtatgtt tgattaaaag
    17221 taataaagtg aggaaataaa atggcatttt catttgatac ggcatccatt caaggtgcaa
    17281 tcattaaggt aatcggtgtt ggtggaggtg gcggaaacgc tattaaccgc atgattgatg
    17341 agggggttgc aggtgttgag tttatcgctg caaacactga tattcaggca ttaagctcat
    17401 caaaagcaga aacagttgtt cagcttggtc ctaaattaac tcgtggtctt ggtgctggag
    17461 gtcagccaga ggttggtcgt aaggcagcag aggaaagcga agaggttctc acagaagctt
    17521 tgactggcgc tgatatggtc tttatcactg ctggtatggg tggaggctct ggaacaggag
    17581 cagctccagt gattgctcgt atcgctaaga gcctaggagc cttgactgtg gcagttgtaa
    17641 cacgtccatt tggctttgaa ggcaacaaac gcagtaattt tgccattgag gggattcagg
    17701 agctaagaga gcaggttgat accttattga tcatctcaaa taataacctg cttgaaattg
    17761 ttgacaaaaa gacaccattg cttgaagcgc ttagcgaagc agacaatgtt ttgcgtcagg
    17821 gtgtacaagg gattactgat ctgattacaa gccctggctt gattaatctt gactttgccg
    17881 atgttaagac tgtgatggca aataaaggca atgcacttat ggggatcggt attggttctg
    17941 gtgaggaacg tattgtagag gcagctcgta aggctatcta ctcaccatta cttgaaacaa
    18001 caattgacgg tgctgaagat gttatcgtta acgtgacagg tggacttgat atgaccctca
    18061 cagaggctga ggaggcatct gaaattgttg gtcaggcagc aggtcaaggc gttaacatct
    18121 ggctaggaac atcgattgat gactctatga gagacgaaat tcgcgtaaca gttgttgcaa
    18181 caggtgttcg tcaggataag gcggagcaag cctcaggatt tcgtcagcca cgcacctaca
    18241 ctcagtctaa cgctcagcag gctgctggag cacaatatgc ttcagagcag gtgagacaga
    18301 ctgcgcagcc aagctttgat cgtcgttcat caagctttga ttttgatatg ggtgaaacac
    18361 gtgagatgcc taagtctcag caagctatgc cagctcatgg ccacaatcat aatcagggct
    18421 cagcttttgg aaattgggac ttacgtcgag acaatattgc tcgtccagca gaaggtgagc
    18481 ttgacaatca attgaacatg tcaaccttct catcaaatga tgacattgat gatgaattag
    18541 aaacaccacc atttttcaaa aatcgttaat gatggattta caaaaaaata aggatattgt
    18601 ttttgaaaat attcgcttag ccactcaggc agccaaccgg cctgaaaaca gtgtgtcagt
    18661 tatcgctgtc acaaaatatg tggacaaggc agttgcaggt cagctgattg atatggggat
    18721 tgagcatatc gctgagaacc gtattgataa gtttctagat aaatatgaag ccttgaaaga
    18781 taggcaagtt acttggcatt ttatcggtac tttacagcgt cgaaaggtaa aggaagtgat
    18841 taataaggtt gattattttc atgccttaga ttcagtaaaa ctggctttag aaattgaaaa
    18901 gagagctgac caccctgtga agtgttttct acaagttaat atttctgaag aagaaagcaa
    18961 gcatggtttt aagattgctg agcttgatgc tgctattgag gaaatcagca agatggaaaa
    19021 gcttcatctt gtcggtatca tgacaatggc acctattgat gccagtcagc aagagcttag
    19081 aagcattttc caaaaagcaa atcaattaag aaaaaacttg cagtcaaaaa agagaaagaa
    19141 tatgccgttt acagaattga gtatgggcat gagtaacgat tatccaattg ctattcaaga
    19201 aggctcaacc tttgttcgta ttggaacatc tttctttcac taaatggaga ataagatggc
    19261 aattaaagac gcatttaata agatgatttc ttattttgat actgatgggg tcagtgaagt
    19321 agaagaggag ctatcctcta aaaagcaaga agagcctgtg actaaatcac aacagaccag
    19381 cagacctaat cagcagcaac aagcagctag agcgagtcag ccccagcagc ctaagcaggc
    19441 tagacctcag atgcaagctc agcaaagacc acaatcacaa tcaagagctg cctatgctga
    19501 gcgaccatat caaggtcaaa gtcaagcacg tgtttctcat gactacaatg acagaagggc
    19561 gacgtcagcc ccgtctgctt ctagtcgtcg tgagcaatat cagcatgctg ctcatcaaga
    19621 gcaaacaact attgccttga agtatcctcg taagtatgag gacgcccaag aaattgttga
    19681 tcttttgatt gttaatgagt gtgtgctgat cgattttcaa tacatgctag atgctcaggc
    19741 aaggcgttgc ctagatttta ttgacggtgc tagtaaggta ttgtatggta ctctgcaaag
    19801 ggttggttct tccatgtatc tgttgacccc atcaaatgta tctgttaata ttgaagagat
    19861 gaatatccca aataatggcc aagatattgg ttttgatttt gatatgaaga gacgctagtg
    19921 tgatgatttt tatactgttg atacttctaa agctaattaa ggtttattcc tatttgctgc
    19981 tagtctatgc cttactgtct tggtttcctg gagcctacga ctcttggctt ggcaggctgg
    20041 tcagcgatat agtagagcct atcttaaaac cctttagatc attgaaccta cagtttgcgg
    20101 gcttggactt tactatttac ctagtgatga ttggtctaaa tgttttaagt gagatcttga
    20161 taagagtgtt gatctcatga ctgttcaaac aatgctttat cagcattttc agcctgatga
    20221 acacccattt attgaaagaa tgcttgactt gatcgctcgt gttgaggcta attatttatt
    20281 agaggttact gattttttaa atccgcgaga ggtcacgatt ttaaaaggct tagtcgcagc
    20341 aaccaatctg cagtgcttta gctctactga ttattatcct agtgaatatg gtcgtgtgat
    20401 tgttgctcct gactattatt gtctagataa ggcagatttt gacttggctt tgattgaggt
    20461 gacctataat gctaagttta atcagctgac acatgcacag attttaggca ccttaattaa
    20521 tgaattggga atcaaaagag ccttacttgg cgatattttt gttgagatag gtcatgctca
    20581 ggtcatgatt aatcgacagc tgttaagcta ttgtttagga acgattgcta aaatagcaaa
    20641 agctagggtc aagctcaaag aaattgatct tgatcagctg ttaaatctga cagctaatca
    20701 gcaggttctg actgatataa tggtatctag tctacgcgtt gatcgcttga ttgctaccgt
    20761 attaaagcaa tctagaaatc aggcgataag gcttgttgaa gcaggcaagg tcaaggttaa
    20821 ctatcagctt gtcactaaag cctctcagcc tgtagctgtt ggtgatttaa tcagcattcg
    20881 tggctacggt aggtttagca tactaacaga caatggcttc acaaaaaatg ggaaatataa
    20941 gctaacactt agcaaaatga tgcgtaaata aggagatata atggcactta cagcactaga
    21001 aattaaagat aaaacgttta agacaaagtt tcgtggctac agtgaagagg aagtaaatga
    21061 atttcttgag attgttgtag acgattatga ggctttggtt cgcaaaaatc gtgataatga
    21121 agctaagata agagagcttg aagaaaagct gtcttacttt gatgagatga aggaatcatt
    21181 gagtcaatct gttatcctag cccaggaaac agctgaaaaa gtgaaatcct cagcaaatgc
    21241 tgaagcaacc aatttggtca gcaaggcaac ctatgatgct cagcatttac ttgatgagtc
    21301 aaaagcaaag gctaaccaac tgttgcgcga cgcaacagat gaagcaaagc gcgttgctat
    21361 tgagacagag gaattaaagc gccagacacg cgttttccat cagcgcttgg tttcagctat
    21421 tgagtcacag ctaagcttat ccaattcgcc tgagtgggac gaattgttgc agccaacagc
    21481 tgtctacctt caaaactctg atgcagcctt taaagaggtg gttaaaactg tccttaatga
    21541 agatattcct gaggctgatg acagcaattc ctttgatgca acacgtcagt ttacaccaga
    21601 ggagctagag gagctgcagc gtcgtgttga agaaagcaat aaggagctag aagcctatca
    21661 ggtgcagcga gaagagcaag ctagcgagcc tgaagtgaac ctaagcgaga cacagacctt
    21721 taaattgaat atttaatcat aagaaaaaca ggattgaatg cccaaaatca cagcaagtag
    21781 gagatgatga gagtcctata ttccctgagc atgacaatta tcattttctt caatcatcac
    21841 tgaatgacag taagtgacga gggaggctca ccttacgagc aaagagggaa cagcaaaagg
    21901 gattttactg ttctgaatta aggtggtacc acgagctttc gtcctttttg agacggggct
    21961 ttttttgtaa ttctgataag atattgacta aaaggagttt gacaagatga aattaaaaga
    22021 aacacttaac ttaggcaaaa cggcctttcc aatgcgtgcc ggtctaccca acaaggagcc
    22081 acaatggcaa aaggcttggg acgaggctga gatttacaaa aaacgtcaag ccttaaatga
    22141 aggcaagcct gcctttcacc tgcacgatgg gcctccctat gcaaatggta atatccatgt
    22201 cggacatgcg ctgaataaaa tttcaaaaga cattattgta cgtgccaaat ctatgtcagg
    22261 ctatcaagcg ccttttgttc caggttggga tactcatggc cttcctattg agcaggtctt
    22321 ggctaagcag ggggttaagc gtaaagagat ggatctggct gactatcttg acatgtgtcg
    22381 tcagtacgcg ttaagtcagg ttgataagca aagagacgac tttaagcgtc tcggtgtatc
    22441 tgctgattgg gacaatcctt atgttacctt agatccaagc tttgaagccg atcaaattcg
    22501 tgtctttggt gcgatggctg ataagggcta catttatcgt ggggcaaagc ctgtgtattg
    22561 gtcatggtcc tctgaatctg ctcttgctga ggcagaaatc gaataccatg atattgattc
    22621 tacatcgctt tactatgcta atagggttaa agatggtaag ggaatccttg atactgacac
    22681 ctatgttgtg gtttggacga ccacaccatt tacggtaaca gcttctcgtg gtctaacagt
    22741 tggacctgat atggattatg tggttgttag acctgcaggt tcagaccgta actatgtggt
    22801 ggcagaagga ctgctagaca gtctggctgc taagtttgct tgggaatcat ttgagatttt
    22861 ggccaatcat aagggctctg acttggaata cattgtaacc gagcaccctt gggacagtga
    22921 ggttgatgag ctagtcattc ttggcgatca tgtgacgcta gattcaggta caggtatcgt
    22981 tcatacagca cctggctttg gtgaagatga ctacaacgtt ggtatgacat atggacttga
    23041 ggttgcagtt acagttgatg agcgtggttt gatgatggaa aatgcaggtc ctgattttca
    23101 tggtcaattt tatggcaagg taactccgat tgttattgaa aagcttggag acctattgct
    23161 tgctcaagaa gtgatcaacc actcctatcc atttgattgg cgcacgaaaa aaccaattat
    23221 ttggcgggct gttcctcagt ggtttgcttc tgtgtctgac ttccgtcaag agattctaga
    23281 tgagattgac aaaacaacat tccacccgac atggggaaag acacgactct acaatatgat
    23341 tcgtgatcgt ggcgattggg tgatctctcg tcagcgtgct tggggtgttc cactgcctat
    23401 tttctatgca gaggacggca cagccattat gactaaggag gtaactgatc acgtcgcaga
    23461 tctgttccaa gagcatgggt ccattatttg gtggcaaaaa gaggctaagg agcttttacc
    23521 tgaaggcttc acacacccag gctctccaaa tggggtattt accaaagaga cagatatcat
    23581 ggacgtctgg tttgattcag ggtcttcttg gaatggtgtg atgaatgctc gtgatcatct
    23641 tgcttatcca gctgacctct accttgaggg ctccgatcaa tatcgtggtt ggttcaactc
    23701 atcactgatt acctcagttg cggttaatgg tcatgcaccg tataaggcta tcctatcaca
    23761 gggctttgtc cttgatggta agggtgaaaa aatgtctaaa tctaaaggaa atatcatttc
    23821 acctaatgat gttgcaaagc aatatggtgc tgatattctc cgtctctggg tagcttctgt
    23881 tgatacagat aatgatgtgc gtgtgtcaat ggatatccta ggacaggtct ctgaaaccta
    23941 tcgtaaaatc cgtaacacgc ttcgcttctt gcttgctaat acatcagact tcaatccaca
    24001 tacagataag gtggcttatg ctgagcttgc tgctgttgat aagtacatga ccatcaagtt
    24061 taacaagcta gtaggagcta tcaatactgc ctatgagcgt tatgacttca tgacgattta
    24121 caaggctgtg gttaactttg tgacggttga cttatctgct ttctaccttg attttgccaa
    24181 agatgtggtc tacattgagg ctgctaacag cctggcacgt cgtcgtatgc agactgtctt
    24241 ttatgatatt ttggttaata tcactaagct attgactccg atccttccac atacggcaga
    24301 ggaaatctgg tcatatttag agcatgagcc agaagacttt gtacagctat cagagctgcc
    24361 acaggctcag acttttgata atcaagatac tatcctagag gaatgggaag cctttatgac
    24421 gcttcgggca caggcgcaaa aggctttgga ggaagcacgt catgacaaga ttattggtaa
    24481 gtccttagaa gctcatctga caatttatgc aagtccagag gttaagacac tgttgacagc
    24541 tctagatagc gatattgcac tgctattgat tgtctctcag ctaaccatta gtgaggagcc
    24601 agctcctgag aatgctgtca gctttgatga tgttgccttt acggtagctc gtgcgcaagg
    24661 agaggtttgt gagcgttcac gtcgtatcga tccaacgacc agaatgcggt cttataatgc
    24721 ctttgtttgt gaccacagtg cgaaaattat cgaagaaaac ttcccagaag cagtagcaga
    24781 aggctttgac tcagctgcta attaagcaac taacagctct gttcccgagt taaataagca
    24841 ttggcgtgct tttgccaatc cagcagcaag gtgctagtcg gtctgggcgt acctgcctta
    24901 ctagggactc tttgtgtggg agctgataag tgacctgcct tgagcttggc aggtctaggc
    24961 ttctttatag gttcacgatt tacgattgac tgggcttaga gaagggctag tcctgctagg
    25021 cggcattgga tatgaactga gtagtcatca tagctataaa aaaacaagcg cagactcacg
    25081 tcagcttaat cgtgagcggc gcttgttttt tcttggttgg ggggtgaagg cgaggagcta
    25141 ttaaagctaa tattaagcga tcaaaaaagc ctagaccact agtcatgttg tctaagcttc
    25201 agctgttaga gaggagcttt ctgagtggaa ggtagcctat gctgataggt gctgccttag
    25261 ccttttagca gtagtattaa ggctagacag acgtctggaa ggaaatttca atcaaattat
    25321 tggtgtgcag ggtttttgag tgacctggaa tcacaataga ttggtcaatc ttacgcttta
    25381 agaaaaattc gcgaatcact tcaagctcgt cctctttgat ggcacgatat ttatttgaaa
    25441 tgagtagctc ataatgcttg ggtgcttgcg taaagatgac gtcagtgtta ccagctgagt
    25501 aaacttcaac gaggtgagca tctgtatttt gcagctgatt tctgacaagc tcggggtgac
    25561 tgctggtggt attaataagt ctcataaatc ttctcctgac tatttttact tttattatag
    25621 cactattttt aaattgatta cggattttaa tggtgctttt tctgccattc ttcgacgccc
    25681 catctgtggc tatcacgctt taagactgtt atggcgtccg caataggaag aaaccaagcc
    25741 agatggttaa agtcttccaa gggctttgag atagcttgga atgatgtcac ctcgtacagg
    25801 taggcaggat tatagtagta ggtatcgcgg tgacgagaat agaagtattc gtctgcttga
    25861 ccataataat aaccaatatc agcagcaaat cccagctcct caactagctc acgctccagt
    25921 gcctgtagct ggctttcacc agcctctatt tctcctcctg gcaaaaacca agcaccattt
    25981 ggagcctgca ctaggataat ctctgtttta gccgagttag gaatcactgc atagacaccg
    26041 taacgtgcgg tgtaatgctg gtcatctatc ttatcaccaa atattggaac ggtcatatcg
    26101 cttctccttt gttttattat actaaatttt tggtcattat tctcataaaa ctgtagattt
    26161 atcaaaaatg tttcataaaa aaatgctcgt caaaaagaga gaaaatgctg tctgcttttc
    26221 tctctgcttt tctctctgct ttttggtatg ccctgttagt ccgcctgctt cgcctgagat
    26281 ttgactacag gcttgattat aatgtgtcca ttagaggtca agacagctcg catgtctttt
    26341 tctgctgggt gctcaaggta gaagtcagta atggcgtcct caatgtagtc ctgaatggtg
    26401 cggcgcaatg gtcgtgctcc catcttagga tcatagccta gctcaacgag cttttctttg
    26461 accttttggg tgacatcaag gcgaatgtta ttgtgagcaa ggcggtggtt aacatcatcg
    26521 agcattaaat gaacgatatg taaaagattg tccttgctta gtggctgaaa ctcaataatg
    26581 ccatcaaagc gattcatgaa ctcggggcta aagaaatgac tgagctctcc taaaacagag
    26641 tttgtccgcc cttctctagc agcgccaaag cctactgagg cctctgtttt gccagtgcca
    26701 gcatttgatg tcatgatgat aatagtgtcc ttaaagctaa cggtacgtcc ttgtccgtcg
    26761 gttaatcgtc cgtcatctag gacctgtaaa aacatgtgca tgacatcagg gtgagccttt
    26821 tcgatctcat ctaacaaaat gagcgagtaa gggttgcggc gcacctgctc tgttaactga
    26881 cctgcctcct catagccgac gtagccggga ggggcaccga caagcttagc cacagcgtgc
    26941 ttttccatgt attcagacat gtcaaagcga atcatgttat cagcagagcc aaaaagctca
    27001 atggctaatt gcttggaaag ctctgtttta ccgacaccag ttgggccaac aaagaggaag
    27061 gagccgatag gacgatttgg ggctcccagt ccaacacgat tacgacggat agcttttgca
    27121 attttatcaa cagcatcgtc ttgaccgata acatgctttt tgagatcggc ggccagattg
    27181 actagctgtg attgttcctt ttcctttaaa tcaccaactg gaatattggt tttttgctca
    27241 acgattgctt cgatggtctt gtcagtgatg attggaatat cctgctcatc tagcttttga
    27301 gcctgcattt ctttatattt ggcgatttga tcgcggaaat aggctgctcg ctcataatcc
    27361 tcatcacgtg tggcttgtgt cttgaggttt tcagcctcaa tcaaacgctt atcaatgtct
    27421 ttggggtcaa caaagttaag ggttaggttc atctttgagc cggcttcatc tagcaggtca
    27481 atggccttat caggcaagaa gcggtcttga atatagcggt tggagaggtt agcagctgct
    27541 tcaatagccg actggctata tttgacatgg tgatagtcct catatttggg ttggattcct
    27601 tttaggatag tgattgtttc ttcaaccgaa ggctcgtcca ccttaaccgg ctgcatgcgt
    27661 cgctcaaggg ctgcgtcctt ttcgatgatg cgatattcat tgagagtggt cgctcccact
    27721 aattgaagct caccacgagc aagtgctggc tttaaaatat ttcctgcgtc catgctgccg
    27781 tcaccaactg caccagctcc cacaatttca tggatttcat caataaatag aatcacgtca
    27841 tggcgcttgc ggatttcctc catgagcttt tgcatgcgct cttcaaattg gccacgaata
    27901 cctgtcccct gaacgaggct aaccacatca aggcgaatca cctgcttact ctgtagcttt
    27961 tgtggcacat cgccatcaac gattttttga gcaaggcctt caacgacagc agtcttacca
    28021 acacctggtt ctccgattag gacagggtta tttttggtac gacggttgag aatctcgatc
    28081 acgcggataa tctcatcgtc acgtccgatg acaggatcaa tatcaccacg cttagccatt
    28141 tcagtgatat taatgccgaa ttcctcaagc aaacctttgt tagcctcttg tgctggctgt
    28201 gtgtgattgg gacggtagcc attgtgacct ccgccattat ggccgcctga ttgggtaggt
    28261 ggtgtattgg gcaattgacc gaaggctcta aaattgttca ggtcaccaaa aaagtcatca
    28321 aagaaagggt tttgagaagg ctgctgcgcc ttttggttgc cattatagcc tcctaagata
    28381 ggatttttag ggtctgtttt catgatttgg tagcaatttt gacagaggtc aatctgcctt
    28441 tgctttccgt taatgcttgt ataaagatga atggttgatt cgtttaaatt acagttttga
    28501 caaagcatat catacctcca aggggttatc taaaaagtca aggtcattta gtcaaaaatg
    28561 gtcaaacttt atagtcatat tatagcacct taggcttgga aatcaagtaa aaagcttcat
    28621 tattagcact ttcaggtata gagtgataat ctctataaat cttgctgctc attggttcaa
    28681 aaaagtcgtc aaaggggata aaataaagag aaaatggcta cttttcttgt ttgttttcga
    28741 tgatttatgt taaaatatat agggacaata aacgaatagg agaaacgaaa tggaatcaca
    28801 tttagtgaga atcatcaacc gtctggagct gatggtaaca gatggcggta atttaaagag
    28861 aaactttgag cgagatggtg ttgttgttgc agaggttgca tttgtcaacg atcctgaaaa
    28921 tggtccagtc tttattttac gtgatattga agcgcgtgag tcatattcat ttgatagcat
    28981 cgatttgatt gcgatggaaa tttacgattt gttatattaa gctattgatg atgacatggg
    29041 cttgctggga ggcaggtcag acagaggaca agctggtgat ttactggttt gtttttatta
    29101 tcccttaaag cctcaagaca gctccaggaa aggcctttct cctatggtct ttctagccgg
    29161 tagggcttga tagtgattaa tagtgatctg ctctagcacg gtcttgagct tttactgtca
    29221 gaggcttgtg accttagcca ctcgcagtaa agggtactgg cccagtaagc aaggtaggct
    29281 aagtatcaat gtgaagttct aaccttgatc ttagtgaaat atttttgagg tgaattaaga
    29341 tgttaaaagt ccttagaatg ctcatttcta agggttttgt tgtgtctagc tgttggtgtt
    29401 tgaaagagcg gtggtatgat aaagagaggt cagaaaagac ctctctgatg tttgtgatta
    29461 gctgttagct attgccatag gggaaagaca caatagctag cttagctttt ctttttcttt
    29521 aggtttagga cgcctgcgct agtgatgacg ctaagggctg caagggtgaa gaatgggtga
    29581 tttgtctccc ctgtagctgg tagcgtgctc ttttgagctg ctggtgctga cttaggcgct
    29641 ggtgctttag gctgagctga tttttctgga gcctttggtg caggtgtctt ttcaggtgct
    29701 tttggagctg atggttttgt atcttttcct tgatcaccct ttggtttttg ctcgcctttt
    29761 tcgccgcgtt gtccttgctc gcctttttcg ccgcgttgtc cttgctcacc tttttcaccg
    29821 cgttgtcctt gctcaccttt ttcaccgcgt tgtccttgct cacctttttc accgcgttgt
    29881 ccttgctcac ctttttcacc gcgttgtcct tgctcgcctt tttcaccgcg ttgtccttgc
    29941 tcaccttttt caccgcgttg tccttgctca cctttttcac cgcgttgtcc ttgctcgcct
    30001 ttttcgccgc gttgtccttg ctcacctttt tcgccgcgtt cgcctctgtc acccttaggg
    30061 ccggctggtc cttgttcacc tttaggacct gtttctccgg tttcgccttt atctccacgt
    30121 ggtcccatag gcccaacagg accttgctct ccgcgttccc ctctaggtcc ggcaggcccc
    30181 acaggtccct gaggaccacc ttttttagct tgtagttcta agttttgtaa gtaggtttgc
    30241 atgaattgtc ttaatgtatg taggtatact cttacttcgc catctccgag tccgtcccta
    30301 attagttcag ctggatctgg ataggactct aatcgcgtat aatcttcagc tcgggcattt
    30361 ccagctgttc ctaggctggc cattgttgct agggcaatgg ctgctgagca gacgctgtac
    30421 ttgcgtattg tttttttcat ctttctctcc tttgatgata gtatcattac tttttcaaaa
    30481 ttctttcccg aagaagagtt taacatggta gcttgctatg agaaacagct aggcgccact
    30541 ttgtctccgt agttttttta attcaatgct gaatcgtctg attttatcag agggttattg
    30601 tttttaaagg cgaggagttg ctttgctcag ctagtctagc aagttcacag gtcagcttat
    30661 gtttcttatc aagcttgttt gtttttgaga atatttttcg ataaaaagat gttgtattaa
    30721 tattcatgtt atagtataat tatattcgtt gccatgactt tatgaatgtt aggagatagg
    30781 aatggatttt acctttttac ccaaatactg ggcttatttc aattatggtg tgcttgtaac
    30841 catgatgatt tcagcctgtg ttgtcttttt tggcacgatt ataggtcttt tagtgaccct
    30901 gataaaacgc agtcatatca agcctttgtc ttggcttgtc agtctttatg tctggatttt
    30961 tcgtggaacg ccgatggtgg tacagatcat gattgctttt gcttggctgc atttcaacga
    31021 tctgcccatt gtaggctttg gtgtgttgga tttggatttt tcaagactgc ttcctggtat
    31081 tattattatt tccttgaata gcggtgctta catatctgaa atcgtcaggg ctgggattga
    31141 ggcggtgcca aaggggcagc tggaggctgc ttactctctt ggtatccgtc ctaagaacgc
    31201 catgcgctat gtgattttgc ctcaggcctt taagaatatt ttgccggcct tgggcaatga
    31261 attgatcacc attatcaagg atagtgcctt gcttcagacg attggtgtga tggagctttg
    31321 gaatggagct cagtcggttg tgacggcgac ctatctgcct attacaccct tgctgtttgc
    31381 ggccttttat tacttgatga taacaacaat attgtcgcaa ttattaggct gcttggagcg
    31441 caagctagca cagggaggga gataagatga ctgagacagt gatttcgatt cgtcagttgc
    31501 ataagagctt tggcaagcat gaggtgctaa aaggaataga cctgaccatt aatcagggtg
    31561 aggttgtggt gattattggg ccatctggct caggaaagtc cacgctattg cgcacgatga
    31621 atttgcttga ggtgccaaca aagggacaca tcagctttga gggcgtcgat attacggata
    31681 aggcaaatga tattttcaag atgcgtgaga agatgggcat ggtttttcag cagtttaatc
    31741 tgtttcccaa tatgacagtg ctggaaaaca tcaccctgtc acccatcaaa acaaaaggaa
    31801 tgtcaagggc tggcgcggag cagagagctt atgagctgct tgagcgagtt gggctgagag
    31861 ataaggctgc tgcctatccg gcaagcttat ccggtggtca gcagcagcgc attgcgattg
    31921 cgcgcggctt ggcaatggat cccgatgtgc tgctctttga tgagccgacc tcagcgcttg
    31981 accctgagat ggtgggtgag gttttggctg ttatgcagga tttggcaaaa tcaggcatga
    32041 cgatggttat tgtaacgcat gaaatgggct ttgccaaaga ggtggcggat cgcgtgattt
    32101 ttatggacgg tggtcttgtg attgaagagg gcagtccagt tcaggtattt gaagctccta
    32161 aggaggagcg gaccaaggac tttttgagca aggtattgtc atagctggcg cagctaaagg
    32221 gcagcatgtc acctcaaggt ctggctatta gtcaattggc tgtttgtttt gggcattttg
    32281 tttgtaaaag gcttagaaag tctggttggt gctgtagcca tatctggctt tgctacgctt
    32341 gggctgctag ctggtcagtg ggtatcatag tgattggagg tgtggtctct ttattggtca
    32401 acattgctgt ggcaggctag cacaggggct ttgcttgttg tgctgggtaa ggggtttcat
    32461 ttgcatgact gttaacattg cttaattgat gaattaggtt gacttttgtt ttattgtttg
    32521 atactattca ggtaagtctg tcattagaaa gcgctttgct tttttgatga tggaaatcat
    32581 gatcatatga tcacgtctta ggtaatatgt tgttgtcaac atggtggtct gaaagtagga
    32641 ggataatatg gactacaaag ctgtttatca ggagtggctg cacaatgatt ttttcaatga
    32701 agaaatcaag gcagatttag aggcgattaa gcatgatgag gctgagattc aagaccgttt
    32761 ttataaggtg cttgagtttg ggacagcagg acttagagga aagctcggtg ctgggaccaa
    32821 ccgtatgaat atttacatgg ttggtaaggc tgcgcaggct ttagctaata ccattattga
    32881 tcatgggcca gaggcagtct cacgcgggat tgccatcagc tatgatgtgc gctataagtc
    32941 taaggaattc gcagaattga cctgctcgat catggcagcc aatgggatca agtcttatat
    33001 ctacaagggg attcgtccga caccgatgtg ctcttatgcg attcgtgcct tgaactgtat
    33061 ctctggtgtc atgattactg ctagtcacaa tcctcaggcc tacaatggct acaaggctta
    33121 ttgggaagag gggtcacaga tcctagatga cattgctaat cagatagcgg ttcatatgga
    33181 cgctattgag cgctttgagg acgttaagca gatacccttt gaggaggcat tggcaagtgg
    33241 tctgaccagc tatattgatg atagtataga ggaggcctat aagaaagagg ttttaggctt
    33301 gaccatcaat gatactgata ttgataagtc agtgcgtgtg gtttatacac ctttgaatgg
    33361 cgttggtaat ttgcctgttc gtgaggtatt gaagagacga ggctttgatc atgtctttgt
    33421 agtgccggag caggaaatgc cagacccaga tttcacaaca gttggttatc caaatccaga
    33481 ggtaccaaag gcctttgctt attcagaaag actagggcaa gaagtaggag cagctattct
    33541 gattgcgact gatccggact gtgatcgtgt ggcactagag gttcgagctg ctgacggtag
    33601 ttatgtcttt cttaatggta ataagattgg tgctttgttg tcctactata tcttttcaca
    33661 gcgtcatgct aggcataatc ttcctgacaa tcctgtcctt gtcaaatcaa ttgtaacagg
    33721 ggatttatca aaagctattg ccgctaaata tgacgttgaa acggttgaga ctcttacagg
    33781 ctttaaaaac atctgtggta aggctaatga ctatgacatc acaaaggaga agacctacgt
    33841 ctttggctat gaggaaagca ttggtttttg ttacggtacc tttgtgcgtg ataaggacgc
    33901 ggttagcgcc tcaatgatgg tggtagaaat ggctgcctac tacaagcaaa ggggtcagtc
    33961 actcttagat gtgcttcaag acatttacaa ggaatttggc tattacaatg agcgtcaggt
    34021 agcgctagag ctagagggtg ttgaggggca gaagcgtatt gcacgtatca tggaggactt
    34081 tagaaatgag cctattgagc atgcaggtgc tatgagcttg aagaccattg tagactttaa
    34141 ggacggctac cttgattttc caaagcaaaa ttgtttgaaa tattattttg atgatgggtc
    34201 atggtatgcg ctgagaccat ctggaacaga gcctaagatc aagctttaca tctatactat
    34261 tggtgaaaca gaggcagaca gcattgctaa gctagacgct attgagtcag cttgtcaagc
    34321 aaagatggac agtgtcagct aattgttcaa gctctgcaac agaaaatcag ctaatcaata
    34381 agcaaaaagg aaaaggaagt gacagtgctt ccttttttcg ttataatagt taaaaaatta
    34441 gcaaggagtg catatggtac agattattga tgggaaggcc ctagcacaga aaatgcaggc
    34501 agcattggct aagaaggtag agagcttaaa ggcagaaaaa ggaattgttc caggccttgt
    34561 tgtcattctg gtaggagaca accctgctag tcaggtttac gtccgtaata aggaacgcgc
    34621 tgccttagca gcaggcttta aaagtgaaac cgttcgcttg tctgattcag tctgtcagga
    34681 agagttgata gagctcattg agcaatataa tcaagatgat acgattcatg gtattttagt
    34741 gcagcttcct cttccgcacc atattaatga caaaagcatt atccttgcta ttgatcctaa
    34801 aaaggacgtc gatggctttc accctatgaa tacaggtcat ctgtggtcag gtcgtccgaa
    34861 tatggtccct tgtactccgg cagggattat ggagatgttt catgactatg gtatcgaact
    34921 tgaagggaaa aatgctgtta ttgtcgggcg ctcaaatatt gttgggaagc ctatggcgca
    34981 gctactgttg gataaaaatg ctacggtaac gcttacccat tcgcgcacgc gccgactggc
    35041 agatatttgt cgtcgtgctg atatcttgat tgttgctatt ggtcaggggc attttatcac
    35101 aaaggagttt gttaaagagg gtgctgttgt tatagatgtt ggtatgaatc gtgacgtcaa
    35161 tgggcgattg attggagacg tcgcctttga tgaggtgtca gagctggcta gcatgattac
    35221 tcctgttccg ggtggtgttg gaccgatgac cattactatg cttttggagc aaacctatca
    35281 agcagctcta agaagggtga gtcaatgatt atagatcaat cgtttgttgc tagggttgtt
    35341 gttccgcggc aggctgactc ccataagggg agttacggca gagtactgtt agtaggtggc
    35401 ttgtatccat acggtggtgc tattattatg gtagcgctgg cctgtgttca tagtggtgct
    35461 ggcctagtaa ctgttgcaac tgatagagaa actattgctg ccttgcatag tcatttgcca
    35521 gaggcgatgg ctattgcggt agatgatgag gaattactgt tatctcagct aggtatggca
    35581 gacctgattt tgattggtcc ggggctgtcg gagaatagca gagcagctag gctgtttgaa
    35641 ttggtccttg cacatgtcgc tgatcatcag gtattggtca ttgatggctc tgccttaagg
    35701 cttttagcga aaagggcagc tgatgttaag cagctgaggt gccctcttgt gttaacgcca
    35761 caccaaaagg aatgggaggc gctgtcaggt ttagcgattg atcagcagta tgatgctgcc
    35821 aaccaagcag ctctcaagca ttttccaagg gctacgattt tggttgctaa aagctcagca
    35881 accaagattt atcatggcaa ccagatctac cggctaagag tgggcggacc ttatcaggct
    35941 acaggtggta tgggggatac cttggcaggt atgatagcag gaatagctgt ccagtttcca
    36001 gagtcaagct tggtggctaa ggttgcttgt gcgacctatc tgcactctgc gattgctgat
    36061 gagctggcaa agactgccta tgtggttttg ccgactgcta ttagctatga gcttcctaga
    36121 tggctaaagg caatcagcac aggccagaag ctaggttgag gctgtgctgc gaggtcgttt
    36181 gggaaaagcg gttaattggt aggcatgaca gcagctggtt tcagtcgttt agctattttg
    36241 agtttagagc tgctagctta agactgggtg ctgctttatg attcaaggaa gctatcattg
    36301 gaaaaacttg tgtcaagctg tagaagccct agctggcttc tttttttgtc tcttttttgc
    36361 tcactattta tgtggaaaca tgatataatt gcattagtat acagttggag cagttaggct
    36421 tcatgaagtg aaaggtaaac tgatggcaga ctatttatcc gtcactcagc tgacaaaata
    36481 tttaaaattg aaatttgatc gagaccctta tctggagcgt gtctatctca ctggtcaggt
    36541 atctaatttc agaaaaagac caaatcacca atatttttcc ttaaaggacg agggagcggt
    36601 gattcaggcc accatgtggg caggagctta taaaaagctt ggctttgatt tagaagaggg
    36661 catgaagctc aatgtggttg ggcgtattca gctctatgag ccaaatggct cgtattcaat
    36721 gatcattgaa aaggctgagc cagacggtat tggtgctttg gcgctgcaat ttgagcagct
    36781 caggcaaaag ctggctggtg aaggcttctt tgatgagagg cataagcagg ccctgccgca
    36841 atttgtgaca aaggtaggta ttgtgacgag tccaagtggg gctgtgattc gtgatattat
    36901 cacaaccatc tcaaggcgtt ttcctggggt gagtattctt ttgtttccaa caaaggttca
    36961 gggtgagggg gcagctcaag aggttgctgc taatattact aaggctaacc agcgtgagga
    37021 tctggatttg ttgattgttg gacgcggcgg tggctcgatt gaggacctgt gggctttcaa
    37081 tgaggaaatc gttgttcagg ctatttttga gtctcgcctg cctgttattt ccagcgtagg
    37141 acatgagaca gatacaacct tggctgattt tgtggctgat cgcagagctg ccaccccaac
    37201 cgcagctgca gagctggcga cacctattac aaaaacagat attgtctctt ggattgctga
    37261 gcagcagagc cggtcctatc aagcctgtct gcgctatatc agacaagggc aggagcgggt
    37321 ggataagctt tcttattctg ttattttcag gcagccagag aggctctatg atgcttatag
    37381 tcaacgctta gataggctta cgacctcctt gatgaccact tttaaagaga cattatcagg
    37441 agctaagcag gagcacttga ttttggagca tcgtttagcc tctgtcaatg tacaggcaag
    37501 gcttgagcgt tatcaggatc gtctggcaac tgcgcatcgt ctcttgatag ccaatatgac
    37561 caatcaatat gacagtaagc tagcaggctt tgagcgagct caagctgcct tgctgtcgct
    37621 tgatacgagc cgtatcattg cccgcggcta tgccctgtta aaaaaggacg gtgtagtagc
    37681 tgcttgtgtt aaggacatta aaaagggaga tcatcttagt attatcatgc gtgatggtca
    37741 attagaagta gaggtagaag atgtcaacga aaaaaatatt tgaagagcgt ttacaagaat
    37801 tagaggctat tgtgacgagg ctagaaaatg gtgatgtgcc actagaagag gccatctctg
    37861 aatttcaaaa gggtatggtg ctgtccaagg accttcaaaa aaccttacaa gcagctgaaa
    37921 agacacttgt taaggtcatg caggcagatg gcacagagct agaaatggat gcctaatgga
    37981 taagctaaca agaattaatg ccacgattca tcagtattat gacaggcagt ctactgtttc
    38041 agcagatctg gaggaggcca ttttatattc tgttgatggt ggaggaaaga ggctccgtcc
    38101 actcatgtta ttggagctgc tagagggctt tggtcttgcc ttgacagacg ctcattacgc
    38161 ggttgctgct gctgttgaga tgattcatac aggaagtttg attcacgatg atttgcctgc
    38221 tatggataac gatgattacc gtcgcgggcg actaactagc cacaagcaat ttaatgaagc
    38281 aactgctatt ttggcaggag atagtctttt tttggaccct tttgctctaa tcgcaggggc
    38341 agatttgccg gctgacctgc tggtgcaatt gattcagcag ttttccttag cgtcaggaac
    38401 ctttggcatg gtcggtggtc agctcttgga catgaagggt gagcatcagc tgctggatat
    38461 tcaggagcta tctgatattc atgccaataa aacagggaaa ttgttgaccc ttccttttgt
    38521 ggctgcgggt atcatagctg agcagtcagc agacgttttg tcttgtctgt gggaggctgg
    38581 taggcttgtt ggacaggcct ttcagataag agatgatata ttagacctta cggctagctt
    38641 tgctgatctt ggcaagacac cgcaaaagga ccttgctgct gcaaaatcaa cctatccgag
    38701 tctgcttggt ttagagcgct caagggctat tttggaggag tctttgagtc aagcgctagc
    38761 tatttttagc agactagaaa gggaagaagg ctttgagtct caggctatta tcaaaaggat
    38821 cgaggggttg cgactaaatg gctaaagaaa gagtagatgt gctagcctat agacagggac
    38881 tttttgaaac gcgagaacag gccaagcgcg gtgtgatggc tgggctagtt atatcagcta
    38941 taagtggctt acgctttgat aagcctggtg aaaagattga tgaggggatc gaactaaggc
    39001 tcaagggtga gaagcttaag tatgtcagcc gagggggtct caagctggaa aaagccttgc
    39061 aggtctttgg gatctctgtg caggataagg tgacaattga tattggtgct tcaacaggtg
    39121 gctttacaga tgttatgcta caggcaggag ctaggctggt ttacgctgtt gatgttggaa
    39181 ccaatcaatt ggtctggaag ctcaggcagg atagtcgtgt tcgaagcatg gagcagtaca
    39241 attttcgcta tgcaaagcta gcagattttt cagaaggtca gccagccttt gccagcattg
    39301 atgtgtcctt tatttctctt agcctgatac tgccgacatt gcactgtatt ttgcaggaag
    39361 gggcagaggc tgttgctctg atcaagccac agtttgaagc agggcgcgag cagattggca
    39421 aaaaagggat tgtcaaggat agactgattc atgaaaaagt gattaagcag gtggcagata
    39481 ctgctcttaa ttgcggattt atcgttaagg ggcttgattt ttcgcctatc caaggtggtc
    39541 atggcaatat tgaatttttg gctcatttag tcaagggaaa gggctccaag gctattgatg
    39601 atcagctcat acagagcgtt gttagcagtg cacataagga atttaaacag catgaaaaag
    39661 agtgaacgat tagatttaat aaaaaaaatg gttttgtctc atgagattga gactcagcat
    39721 gagctattaa agctcctagc tgattatggg ctagagctaa ctcaggccac tatttcaaga
    39781 gacatgaatg aaattggcat tgtcaaaatt ccatctggaa ctgggcgtta tgtctatggc
    39841 ttgtcacagg atagtggcaa gcgggtggtg caaaggcctg cctctatcaa aaaaacgatt
    39901 ttggaaatgt ctgaaaaaac agcgggcttg gagcagcata ttcacctcaa cgttgttcca
    39961 ggcaatagca agctaatcaa acgttatttg atgacagact tttcaggtca attgtttagc
    40021 ctgattgcag atgatgatag tttgctgttg attgcaaaat cagaagcaga cgctgatcat
    40081 atccgtcagg aattgtccct ttggatgcag ggattggtct aaaaaataga gagaagccga
    40141 tgttattaga aatttccatt aagaattttg ctatcataga ggaaatctct ttaaactttg
    40201 aaaacggtat gaccgtactg actggggaga caggggcagg aaagtccatt atcattgatg
    40261 cgatgaacat gctgctgggt gcgcgcgcaa gcactgaggt gattcgacat ggtgctgata
    40321 aggcagagat tgagggcttc ttttcggttg atgctaatcc tcatttagcc gctgtgctgg
    40381 cagaatcagg gattagcatg gaagaggagt tgattcttcg tcgtgatatt tttgctaacg
    40441 gtcgtagcgt cagccgtatc aatggtcaaa tggtcactgt cagcacccta aaaaaacttg
    40501 ggcagttttt agtggatatt catggtcagc atgatcagga ggaattgatg cgtccacagc
    40561 tgcaccagca tattttggat agttttggag atgaggcctt tgaccagctc aagcagtcct
    40621 atcagcagat ttttgatcgc tataaggctt tgcgaaggca ggctcttgag aagcaaaaaa
    40681 atgaaaaaga acatcaggcg cgccttgacc tgctggcctt tcagataggg gaaattgagg
    40741 cagcagattt ggttagagga gaagatgacc tgcttaacca agaaaggcag cgattgctca
    40801 atcacaaaaa gattgctgat accttaacca gtgcctacct ttccttggat aatgaggact
    40861 tttccagtct ctcacaggtc cgctctagca tgaatgagtt gctgtctatt gaggaccttg
    40921 ccccagagta tcagcttata tcagctggtg tgtcagaggc ttattatatt cttgaggagg
    40981 tcacaaagca attatctgat accatcgacc agcttgattt tgatgcaggc agattgcagg
    41041 acattgagct gcgtttagac agcattaata gtctgacaag aaaatatggc ggtggtgtga
    41101 atgatgtttt ggactactat gccaatatta ccaaggaata ccagttatta agcggagatg
    41161 accgttcctc tgatgagcta gaaagggaat taaaggtcct tgagaagcaa ctggtgatga
    41221 ctgcctcaca gctaagtgac aagcgtcatg ccctggctct agagctagaa gccgacatca
    41281 aagctgagct gagagagctt tatatggaaa aggcggactt taaggtccac tttacaaggt
    41341 caaagtttaa tcgagaaggc aatgaaagct tagaatttta tatctcaacc aatccaggtg
    41401 agggctttaa gccgctggtt aaggttgctt caggtggtga gctttcccgc ttgatgcttg
    41461 ctatcaaggc tgccatttct aaaaaagagg acaagacgag tattgtcttt gacgaggtgg
    41521 atactggagt ttcaggacgt gtggcccagg ccattgctaa aaaaatatat aaaattggca
    41581 gctatggtca ggtattagcg atttcgcatt tgccacaggt gattgctatt gcagataacc
    41641 agtattttat ttccaaggaa agcaaggagg agtcgacagt gtctaaggct aagctgttga
    41701 cacaggagga gcggatcgag gagattgcga agatgattgc aggagctgat gtcacagaga
    41761 cagcaagaaa tcaagcgcgt gaattgctag gtaaggactg agtatcatag caaaagcaga
    41821 acagtagctt tagagcaagc ttgcctgctg cacttgtcgc tacatgttca gaatgagcca
    41881 cctgaaaggc aagcaagaag gctagctctt atgcgtatgc tatcagaagc taagtctttt
    41941 tgtctcttgc attggcgagt gattgattga taatattatg ataaatagaa ggactaaaag
    42001 aatactgact gaggaggtaa aatgctgaaa aaaagaatgg gcttggctag tctgctagtg
    42061 ttgatgacct ttgtgtatca gtgctgttca gttactgctg agcagtattc cgatactgag
    42121 gttgaggtgc tgcagattag cgaggagaaa agccagatca tggaaaatca agaggcgctt
    42181 aaagacctca ccacgtcgtc tgatcagcta aagaaggaag ctttaaagcc taaagaggca
    42241 gctaccaaca agagcaagca agaggcttcg acagtttatt tagctgagga cgatcctgta
    42301 accattgata gctctgacga ggaaagcaat caagatatca tagcggattc tgttcctgat
    42361 ttggttatta aaggtgatca ggtggatgta tctgaggtta tggtctctgt aaaggaggat
    42421 tcatcgaaag ttgctaagca aagaactgac gcagcgcagc ggtacagtat agccaagcat
    42481 caattgaccc aaaagcttga ggcctttaat gcggcaacgg accaattgct gaccatgatt
    42541 gctaaaaaat ctgatttgac tggtcagtat tatgtggttg ggcattcgtt gggagaaatg
    42601 ctggctgctc aaaatgagaa aaagcttgct gagcaattag tcatgcaaca aaagcacaaa
    42661 aaaggcttag gctcatcagt cactatttta gacgaattag gacgtgtgat ttctgacatt
    42721 agtggtcata aaggcatgct tccttttaat cgtaagatca gctttaaggt acatcaagtc
    42781 agatacgatc ttccactaac tggtgatcga acagtgctac ctgcccagct ggctggctta
    42841 ctgcttttac taataggtct tatgctgcct aaagtagcta acaagaaaag ctaagatatg
    42901 gtcttggctt ttttatcttt taagagggtg agtttttgac agatgtttta gctaacacca
    42961 agagctagat accagctttg ctttattttt aaaggagtga taaaataaag agacgataaa
    43021 tgaggttaga aatggaactt aagatgggaa ctattaaaat tgttgcagat tcatcaatga
    43081 cgattgaacc agagctaatc aaatctcttg atattacggt tgtaccgctt tctgtcatga
    43141 ttgatagcaa gctgtattct gataatgagc taaaagagga agggcaattt ctacagctga
    43201 tgagagctag taagtcattg ccaaaaacta gtcagccacc ggtagggctt tttgcagata
    43261 tttatgagcg attggtcaag gagggggcga cagctattgt tgccattcac ctctcaccag
    43321 ctctttcagg aacaattgag gcatcacgtc agggagctga aattgcagca gcaccagtta
    43381 cggtattgga ctcaggcttt acagatcagg ctttgaagtt tcaggtggtt gaagcggcta
    43441 gactggctca agctggcgct agccttgagg aaatccttga ggcggtagag gatattaaac
    43501 gaaagacaga gctttatata ggggtatcag cacttgagca cttggttaag gggggacgaa
    43561 tcggtcgtgt gacaggcttg cttagctcct tgctgaatat tcgtgtggtc atggaaatga
    43621 aaaatgatac cctgcaaaca cttgttaaag gacgcggcaa taagaccttt actaaatggc
    43681 tggatagcta tctagcagaa aatagccagc gacagatagc tgaggtggcc atttcctatg
    43741 ctggtcagag ggattttgct gatagcctga agaagacaat cgctacggtc tttgatgggc
    43801 caattactgt tttggagact ggctcaatca ttcaaacaca tactggcgag ggcgcttttg
    43861 cggtgatggt tagatatgaa taagcgaggg tttttgggag gccttatctt ctttttcagt
    43921 gtttttgcct tatcatttgt gatattagct gtccttattc caaagtctga cccacagctg
    43981 aagaaaagtg attttctaaa aaataagaag ataagcctca attatattgc tattggagac
    44041 tccttgacag agggagtggg tgatctcacc aaccaaggag gctttgtgcc cttattgtct
    44101 ggtgatcttg gagactactt taatgctacc gttaatactg aaaattacgg tgtttccggt
    44161 aataccagcc agcaaatttt aacgagaatg actgagaaca aggagatcac agagcagctc
    44221 aaaaaagcta atctcatgac attaacggtt ggtggcaatg atgtcttggc tgttattcgc
    44281 aagaacttag ctaatcttaa ggtatcaagc tttaaaaagc cagcaaggca ataccaagag
    44341 cgcttacgca aaatccttga tttggccaga aaggataatc aggatctgcc gatctttgtt
    44401 ttaggtatct acaatccttt ttatttgaat tttcaggagc taacagaaat gcagacggtc
    44461 attaatgact ggaacaaaaa aacacaagag gttgttgatg actatgacca tgtttacttt
    44521 gttccaatta atgatctatt gtacaaagga gtagatggta aagagggcat tgtccagtca
    44581 acaggagagc aaacaacgat tgtgaatgat gctttgtttt caggggatca ttttcacccc
    44641 aataacacag gctaccaaat catgtcagac gcagtaatgg agacaataag aaagaatgga
    44701 aaagaaatta aaccttaatt ggtggaaatg ggcttttttg ctattattgg cttttaatgc
    44761 agccttttta gcagttattg gaagtcgtat tatacaaata agagagccta agtctgagct
    44821 gatcaatcaa aaagcagcaa agaatattaa aatagggacc ttaacaacca ctaaagagca
    44881 attaaatgag gcagtcgtta gctacctaaa ggattttcag acggaaaaaa tgacctataa
    44941 ggtgtatgcc acctcctcga ccattctctt tgaaggaacc tatcagctct taggatatga
    45001 ggtgccgtta tacatttatt ttcagcctca tcgcttaacc aatggtgcga tacagctgca
    45061 ggttctctcc ttttctgtgg ggaccctttc tttgccggaa aaggacgttt tgcaatactt
    45121 gaaatccagc tataagctgc caaaattcgt tgaagtctta cctaagcaat cggctattat
    45181 tatcaatcta cagcaattgg aaaatgatgc caacatctat ttaaaggctc aaaagattga
    45241 tcttgtcaag gatgatattc gatttgacat ctataagaaa tgagtctaac taacgtttaa
    45301 tacttgacct gtggctgttt tttagatatg ataatatctg ttaaagcgtt aagcttacta
    45361 attatttgga ggattgttaa atggctaaca aacaagattt aatcgcaaag gttgcagaag
    45421 caactgagct tacaaagaaa gattcagcag cagcagttga cgctgtcttt tctgcaatcg
    45481 aagcttttct tgctgaaggt gaaaaggtac aattaattgg ttttggtaac tttgaggttc
    45541 gtgaacgcgc tgctcgtaaa ggtcgcaacc cacaaactgg tgaagaaatt gaaattgcag
    45601 cttcaaaggt tccagcattc aaggctggta aagctcttaa ggacgctgta aaataataaa
    45661 tcaaaaaaag ccctatctca ttaagctgtt tagcctgtga gatagggctt tttccattaa
    45721 ggaaggagtc ttgtttcaat aagtaatctt gtgtgatcgt ctgaaagatt agcgccaata
    45781 atttctaatg tgcactgtct tgggaacaag agttccattt cataaggata aaatgagtag
    45841 ggctgtacaa aagcagcctg gctgccttga gggacctgaa ttcttaattc cactgagcga
    45901 tgtggcatag cagcattttt gatggctgta gtactcataa agccttgctt tgtataatga
    45961 gtgcctggct tgatcgctga taggatctgc ggatcaaagg tcttatcatg gtagtaacga
    46021 gcgagttcct cttcagaagt gcccaattct gttaagaatg tttcataaac atagcgatag
    46081 acgatgatat tccaagggat ggttagctta tgagtagcac tatcaagtaa ggctacagac
    46141 tgctgcagct gggcatccaa ctggctggta tctcccatca cctgttctag ggctaggtta
    46201 atagggctgg cagaggcgta tgtatactga tacatcatct ttttttctgc ttctgtaaag
    46261 gctgtttgag acctccagcg attggtgata atgtatttgg taacatcagg ctcactaaat
    46321 ttataataag gcttaaagct attcccatag ggctcaaaaa caactgtttg tccttcatca
    46381 taagactgtg ccttgatggt tgaaggctga acgacaagca acgataagaa aaatgtaaac
    46441 aagcatagtg tacgaatagc tatcctttga taagataact ttgcgttatg atgttgatga
    46501 gtcatttagc ttttcctcct ttacagtagt gccaagagtg tcatcaccta atgatgatgt
    46561 ctgttgctaa caggattagc cttagttgaa atgattacaa acttccttaa tgtaacaaac
    46621 ataataaaaa taaattattt ttttattata tattagttaa gctcagatga caagctattt
    46681 gatttttttc tgagataatg ttacaaggga tttctaacac caatgactaa ctcagatgaa
    46741 gggctttttc ttggaggatt gcctatagtt acaatagtag gcaagactgg cagtcgccat
    46801 gatacctatt ccaataacag caaaggttgc tagatgaaca gaggctggta tacaggtcat
    46861 gatggtagtt gccagtggca ttaagagaat agcagttgtg acgattgagc taaagactcg
    46921 tcctagcaat gcctcaggaa cttttttttg aacgatagaa aagaagtgaa tgttaaagat
    46981 tgttaaaaag cattcaaacc ataaattccc aagggcaatc acaatgactg gaagcttcaa
    47041 gagagccata gctgttatta gaagcatccc taggccacta aggcctaggg ataggagtaa
    47101 gctttgctga ttatttttaa agagcttgtt agccataaaa gctcctaaga tagcccctaa
    47161 agctcccatc gaaagaagac tagcatagct tgattggctg cctagcagct gattcgaaaa
    47221 aggaattaaa taattgaaag cagcaataaa gaaattcaca agagaagcaa taatcaacaa
    47281 agaaaaaatg tcattgtcat ggtagatgaa ttgcagcccc tccttaatat ctgttaaaag
    47341 ctgaagccta ttgccttggc tgctctgttt agtgatgtgc ctttctttgt ccttgattgt
    47401 atatagacat agaaaggaca atagaaagct aatgctatct agagccaagg ctgttttgat
    47461 gccaaagcaa tccatcacta aaaaagcaag cattggtgag gaaatactga tgatttgaga
    47521 tacgatttct agctgagcat tgaaatgaac aagtctttct gtttcaacta gtgtgaccac
    47581 ataggctcga aaagcagttc cagagaaggc atacgatatt gctaaaagag cattaacagt
    47641 gataagccca taaagcatga tagtagggtt agctatcagg gctaaaagtc cgcagctgat
    47701 agctccgata gcatctgtcc acaataacaa ttgtcgtcgt ttataacgat cagcaatggc
    47761 gccaccgata ggatttaaga tgagtgaaat aaggccttca gctagctgat aataacccaa
    47821 atattgtcgg ccagttgctc cgagtccagc aatcccgctg ctgttgctgt agtcgtaaac
    47881 agtattgcct attttgttaa tagctcgact tgcgagcagc tggtagtcgt ttttgcgcat
    47941 gataaaacct ccaaaagatt atgtggtttt attataaatc agttttttag ggtcttatgt
    48001 ttttttgcaa ataaggctag aggaggctac aaatctttca aaatcctttt ggtaattgtg
    48061 cgctaggtga ggacaatcca ggctctcaaa aatggaaata gcagtagtca tatccttaat
    48121 gccagacaaa cactgtcctc tttggtagtc ctctaagccc tttaaaaata aaaagatggt
    48181 tttttcatat agcttggttt cattattgag tagggctagt atctgctttt gataatagcg
    48241 cgcatagtca agctgatgtc ggtggataca ggtttcccaa atattgagaa gggtgatggt
    48301 aaccaaatgc ttattggttg aaatgctttc gtagtaggta tgattgttta gaatttcctt
    48361 tcccatttta tctaataagg gaatatcaat aaaaagatag agatttccaa ttaaaatcag
    48421 ctcatagata tgccagcttt cagtcctaaa aaggtagtca gtgacctcat caagataagc
    48481 cttaggaaaa ggaatgctag gattgcattt acagataaag ccttggagta gaatgctgtt
    48541 taaatagtaa cgattggtat caggatcagc ttggtgcttt gccaattcct gcttttgcag
    48601 ctgcttgaat ccctcaatat cgcgtgcata ttccagcttg atcagctgcg acatgaattg
    48661 aatttgctct gtctgtttga agttggcagc tatgtccata aattcgctga tttccacttg
    48721 catgctgtct aaagctgtta aaaactttgt tactgataga tcagattcgc cgcgttcaaa
    48781 gcgggataac tgagacaagg acacgtcttt actggcaagc tgctgtaagg tgatatttct
    48841 gttttgtcta atgctgcgaa atgcttttcc caactgatga ttagtcatat tttttcctcc
    48901 tctaatgagt atatcatgta aggcttctgt tgctgtattt tcccgtatgt gcaaaccttg
    48961 aaacttgtct gctgccgcca caaaggcatg aaaacattta cactttttga tagctatttt
    49021 tatcattgat gtagtctttt tcgcaacatt tgtacgggat catcagatta aaattaagaa
    49081 actgatgatg tgacactgta aacatgctaa aaatatgttg aacaatgcct gtagctggaa
    49141 aatgggtaca tgtattttct tcatgcctgc gtcgtgacct gctgctatta aagcttgctt
    49201 gaaagggaaa aagagcttat aatagcagtg agaacattaa aaatgaaagt agagatatgc
    49261 caataattgt tatccttgga cttgctatct tttcggtggt taaggtcatt atttttctat
    49321 gcttttataa agcatttgag aaaaaacaac taaagaagct agaacaggat caaaaagaaa
    49381 ccaagcaggc gattgaccaa gaggagtcaa aaaaagcctt tcccttttaa cataaagcta
    49441 gaaaaagtct gagacctttc gtctcagact ttttttaagg cttatattgt aattgaccac
    49501 gaaaatcgtc tagtgtctgg tagccctttt cagccataat gtcttgtagc tccttagtga
    49561 tacgcttaaa aatagctgga ccttcctggt gcagtgctgt tccaatttgt accatagctg
    49621 cgccgcatag gatatgctca aaggcatcac gtcctgtttt gacaccgcct gtgccaatga
    49681 tctgaataga agagttaagc cgttggtaaa aggcatgaac attagccagg gcagttggct
    49741 tgatgtaatc accaccaata ccaccaaagc cgtttttagg cttgatgacg acctgctcat
    49801 catcaataac caagccattg ccaatggaat taacacagtt ggcaaaggct aaggggtatt
    49861 gattgaaaat ggctgcggct tggtcaaaat ggacaatatc aaaataagga ggtagcttga
    49921 tgcctagagg cttggtgtaa taggaaaaga tcttttttag gagctgatct gtggcttcaa
    49981 agtcataggc cagctgaggc ttacctggga cattagggca cgacaggttt agctcgacaa
    50041 gtccttgata atcagaggcc tgaatagctt ttaggatagt ctcggtttct tcagcagaca
    50101 tgcccacaac agataaaaag tggtgcttgc ttgcttgatc cttttgcatt tctgtgacaa
    50161 tatctaaata atactggtag ccatgattag gaagtcccat tgaattgatt gagccaagtg
    50221 ctgtatctgc atagcgaggc tcagggttgc cctgtcgagg ggctagagta cctgtttttg
    50281 tcacaaagga cccagcctca gaggcctcaa tggctagcag ctcttccttg gtcatgcaat
    50341 acactccagc agcgttcatc aggcaattat taaaggcaaa tgtagcgatt tttgtggcag
    50401 tagaaaccat gttttcctcc atttttagac aaattttttc tattctatca ctagggcatg
    50461 agaatagcaa ggcatttttg caaaatactt gcttgaaggc tttcttttgt gaggttttag
    50521 cgtttttcat gatattaaca aaatgatttt caataaagag aggaatagac tagctttttt
    50581 gacctatttt ttgtaaaata ggagttgtaa aaaggcaaga agcctttaaa cttaataagg
    50641 agatattaac taatggtaaa attggttttc gctcgtcatg gtgagtcaga atggaacaaa
    50701 gcaaaccttt tcactggttg ggctgacgtt gatttgtccg aaaagggaac acagcaggct
    50761 attgatgctg gaaaattgat caaggaagct ggtattgcat ttgatcttgc ctttacatct
    50821 gtgcttaagc gtgctatcaa gacaactaat cttgcacttg agtattctga tcagctttgg
    50881 gtacctgttg aaaaatcatg gcgcttgaac gagcgtcact atggtggctt gactggtaaa
    50941 aacaaggcag aagcagctga gcaatttggt gatgagcagg ttcatatctg gcgccgttca
    51001 tacgatgtgt tgcctcctga tatggctaaa gatgatgagc attcagcaca tactgatcgt
    51061 cgttacgctc atcttgatca ttctgttatt ccagatgcag aaaacctgaa ggtaacacta
    51121 gagcgtgccc ttcctttctg ggaagataag attgcaccag ccttagttga tggtaaaaat
    51181 gtttttgttg gagcacatgg taactctatt cgtgcccttg tcaaacacat caagcaatta
    51241 tcagatgacg agattatgaa tgtggaaatc ccgaacttcc caccgcttgt gtttgaattt
    51301 gatgacaagc taaatcttac tgctgagtac tacctcggtg gtgaataatg ctgtgaggcc
    51361 agacctagct ctggcttttt ttgttatgtg ataaaaaagg cgtttccaac agaaatgtga
    51421 tatgatagtt aaaaagtggt aaaagaaggg aatcttatga aagtaaagga acgccgagaa
    51481 gctattacag ataggttaag ccaagcacaa gaagccatct cagcaactag cttagccaag
    51541 gcattgggag ttagtcgtca ggtgattgtc ggagacattg ccttacttag ggcgcagcag
    51601 cttgacatta tttcaacacc aaagggatat atcctgtcaa atgctttgtt tagtcatcac
    51661 tattctgcta gaattgtttg ccagcatgga cctgagcaga caaggcagga gttggagttg
    51721 atattagcac atgatggcat tgtgaccaat gtggaggtag agcaccctat ttatggcatg
    51781 ctgacagcac cgcttaacat taaaagctca gctgatatca ataactttat tgaaaagctc
    51841 ggagcctcta aggcagaatt attgtcgtct ttgacagagg gtctgcacac tcaccttttg
    51901 tcctgccctg atcaggaggc atttgaagag atcaagagag atctagcagc tgcaggcatt
    51961 ctctatggtg aacaataatc tgatagcagc tggcttcaca gggatttagt cttggcttga
    52021 tagccaatgt ccctcttttg tcgtaggtga tagggaccgc aggacagctc ctagatgctg
    52081 aggccaaagt cttgtggctg ggcctcaaat gaggttaaaa gggaaggaag ctgctatggt
    52141 tatggtgaaa gggctagatt tacccttact tttttgctag gataatcttt tatgctgtta
    52201 ggccgcaggg cttggtgctg caatggctga gatgtgtctg tcttttgtct tagcttttgg
    52261 tgcttgagaa gggctgggat tgagcttatg ctgtggttgt tttttgattt gctaggtgtc
    52321 ttgacatctg tcgcgttttt ggttatacta acgactagta aaaggagata ttatgaccaa
    52381 aaaaccaaca caactgattg cctactcttc tattttggtg gcctttgcca tcttgattcc
    52441 gatgataatg cccattaagc ttattattgg cccggcttcc tttaccctag ctagtcatct
    52501 gcccttgttt ttagccatat ttatatccat tccggtagcg atcttggtgg ggataggaac
    52561 aggtctgggc tttttgctag caggatttcc tatgattatt gttatgcgag ccttctcaca
    52621 cgtgcttttt gcagctattg cggcttttat gctcaaaagg cagcctaaat ggctggaaac
    52681 accgttaaga acctttgttt ttgggattat agcaaatgtg attcatggcc tagcagagtt
    52741 tttagtggtt tatctgatga cagcaacagc agcaactgat ctttcttatt tttggtcaat
    52801 gctaatgctt gttggctttg ggtctttgct gcatggtatg gtggattttt atctagcctt
    52861 atttatctgg cgcttcttaa ggcagaaggg tcatctatca gtgacaagct aggatttctg
    52921 tgagtattta tgttttagta gccaaggctg ttacaggctg aggctctttt ttctgaaagc
    52981 gcttgcattt ttttgaaaaa atgctatact aaagagtgcg tttgtaaata tactaacaaa
    53041 aggagatgtc atgaaaacac cagaacagat attagccgcg acgattacga ttggtgagca
    53101 taaggttgca aagccttttt tggctaaggc tattttaggc tttattggcg gtgcgatgat
    53161 tagtttgggc tacttattgt atgttaggat tgcagctagt gggctggaga cctttggcgc
    53221 tttttctagt attttgggtg cttgtgcctt tccgattggg ctgatcatta ttttgatggc
    53281 tggcggtgaa ttgatcacag gcaacatgat ggcggtgtcg gcagcctttt ttgcaaaaaa
    53341 gattaaggcc aaggacttga tggccaattg gctggtgatt acccttttta atattttggg
    53401 agccttgttc gttgcctttg tttttggtca ttttctgggt ctgacagcta ctggcagctt
    53461 taaagaagag gtcattgagg tggcccatgc caagcttgct gcaactcctc tacaggctat
    53521 tgtttcagga attggctgta actggtttgt tggcctggcg ctttggctgt gctatggcgc
    53581 tagtgatgcg acaggtaagc tccttggaac ctggtttcct gtgatgacct ttgttgccct
    53641 tggttttcag catagtgtgg ccaatgcctt tgttattccg gcggctattt ttgagggtgg
    53701 cgccagctgg atcgattttg cgactaattt tgctctcgtt tatgtgggca atgtccttgg
    53761 cggtgctatc tttgttagtc tcttttatta caaggcttat gatcactcta aggaagcctg
    53821 attagtgctg ttatattttt agactgggag accttattct cagtcttatt tttatatttt
    53881 gtgataaaat aggaaacgac gtttaaaaag gaggagttga taagcatcta atatggcatc
    53941 atggataaaa aagaaaaaag caagcattcc taggcgaatt catctccttt ttttggtgat
    54001 tgtttttttg tttgttgccc tgattttgag attggcacaa atgcagattt atgagaagga
    54061 tttttacaag gcaaagctga cagcgtcaac cgtttacaaa gtaaaaagct ctatgccaag
    54121 gggaaccatt tttgaccgta atgggaaggt tctagtttct aatcgtatca aggacgtggt
    54181 aacctatacg agaagtccca aggctagtgc taaggacatt aaggctttgg ctcatcagct
    54241 agctgcttat attagctatc ctgaggctaa agtgacagtc agagccaaaa aggattatta
    54301 tttggcagat ccagaggctt atgctaagac ggttcaagcc ttaccccaaa aggacaaggt
    54361 ggatcgcttt ggtaataaat tagtcgaagc acagatatat caaaatgcgg cagcctctct
    54421 taaggaaaca gacttgacct attcagacca agagctaaag gttattgcta tttttaacca
    54481 aatgaatgca gcagctgttt ttagcactgt aaagctcaaa acatcagcct tatctgagca
    54541 ggatattgcc atcattatgg ccaataagtc aaaattacca ggtatttcag ttgggacaga
    54601 ctgggagcgt caggtggagg agacaagcct tgctgctatt attggaaggg tctctagtga
    54661 ggaagccggt cttccaaagg aagaagcaaa ggcttatctt aaaaagggct attcgcttaa
    54721 tgatcgtgtt ggaacctctt atctggaaaa gcaatacgag gaggtccttc aaggaaagca
    54781 tgaaatcaga gaaatcaaaa cgagcagatc tggtgaggtt atttcagata aaatagtcga
    54841 aaagggtcag atggggcgga acctgaagtt gagcgtgcca cttgattttc aacagggcgt
    54901 tgagcagatc ttgaatcagc acttccagac agagctcaaa aatggtcagg ctgcttactc
    54961 agaagggatc tatgctgtgg cgcttaaccc taatacggga gcgattttag cgatggcagg
    55021 tctatcacac aatcccaaaa ccggtgagct tcaaaaggac gctttaggga ctattactga
    55081 tgtgtttaca cctgggtctg ttgtcaaggg ggcgaccttg gctgccggct ggcaggctgg
    55141 agtgattcag gggaatcagg tcttgattga tcagccgatt caatttggtg gctcccagcc
    55201 gattaattct tggtttacca gcggtcagca ccctattact gctagtcagg cgctggaata
    55261 ttcatcaaat acttacatgg ttcaggttgc cttaagaatg atggggcagg attacgtgac
    55321 tggtatgacc ttggccaata ctggtatgaa ggaaaccatg aaaaaattgc gggcagccta
    55381 tgccgaattt ggcatgggag tggcaactgg cgttgatttg cctggcgaat ccagtggcta
    55441 cctcatagat caatataata ctgcaaatgt tttgacagag gcctttggtc agtttgataa
    55501 ctatacaacc atgcaactgg cccaatatgt ctcaactatt gctaatggcg gcagtcgcct
    55561 tgcgcctcac attgtagaag gcatttatca ggataatgac cagtcaggac caggtaagct
    55621 aagtaaggct attgagacta ccttgttaaa caaggtgcac ttagctgctg atagtttagc
    55681 gattattcag gacggttttt atcaggtggt caatagcggt agtggctatg ctacaggtag
    55741 ggctcttgca ggaggtcctg ttaccattag tgctaaaacc ggtaccgcag aaacctatgc
    55801 taaggataaa aatggtcagg ctttatctac ctttaacttg aatgttgttg cctatggtcc
    55861 gagtgctagt cctcaaattg ctgttgctgt catgtatcct catgcgacag actctctagc
    55921 caaggcacat caatacgtgg ctaaggatat cattaatttg tacatgaaga tgtataaaaa
    55981 ccaataaagg agaaacgagt gctttaccct ataccaatcg caaaattaat tgaaagctat
    56041 tctaaattac cagggattgg tgttaaaaca gcgacaagat tggcttttta caccattgga
    56101 atgtctgatg aggatgtgaa tgattttgcc aaaaatttat tagcagctaa gcgagaatta
    56161 acctattgct ctatctgtgg caatttgaca gatgatgatc cctgccatat ttgcacagat
    56221 agcagtcggg ataaagagat cattttagtt gttgaggatt ccaaggacgt ttctgccatg
    56281 gaaaaaattc aagaatatca tggctattac catgtgctgc atggcttgat ttctcccatg
    56341 aatggggttg gcccagatga catcaatcta aagagcctaa tcacgcgttt gatggctgga
    56401 gaggcaacag aggtcattgt tgcaacgaat gccacagcag atggagaggc gactgcgatg
    56461 tacatctcac gtctcctaaa gcctgctggt atcaaggtga cgcgattggc tagaggcttg
    56521 gcagtaggat cagacattga atatgctgat gaggtaaccc tgctgcgagc gattgaaaat
    56581 cggacagaat tatagcttag cccattttca gctctctgtc attagccctt atgccatgtg
    56641 ataaggccat aaaggaaggc agattttgtc agagtctttt gaaaagcaag ctcgtttttg
    56701 ttataataag tggtagtcta attcagatag ggaaggttat caatgtctaa acaaacctta
    56761 attttattat acggagggcg ttcggcagag cgtgaagtat cagtgctttc agctgagagc
    56821 gtgatgagag cagttgatta caccaaattt tttgttaaaa cctattttat cagccagaca
    56881 ggtcagttta tcaagacaca ggaattctct agtcggccga ccttaacaga aaggctgatg
    56941 accaacgaca ctattaggct agagcagcag ataaggccta gtgatatcta cgaggagggg
    57001 gctgttgttt ttccagtctt gcatggccct atgggagagg acggttctat tcaaggcttt
    57061 ttagaggtgc taaaaatgcc ttatgtggga actaatatcc tctcatcaag tgttgcaatg
    57121 gataagatta ccaccaaaag ggtcctagag tcagctggta tcccacaggt tgcttatacc
    57181 gtttatattg aggggcagga tttagacagg tgtctggcag agactgaggc agtcttaagc
    57241 taccctgtgt ttgttaagcc ggccaatatg ggctcatctg ttggtatttc taaggcagaa
    57301 tcagaggagg agttgcgtgc agctatcctg ttggccttga cgtatgacag tcgtatcctg
    57361 attgagcaag gggttttggc aagagagatt gaggttggac tgcttggtaa taccgatgtc
    57421 aaatcaaccc ttccaggaga ggtagtcaag aatgttgact tttatgatta tcaggccaaa
    57481 tacattgata atgagatcac aatggctatt ccggcagcta ttgacgaatc agctatgaca
    57541 agcatgcgta cctacgcaga aacagccttt aaggctattg gtgcttgtgg cctgtcgcgt
    57601 tgtgatttct tccttggtca ggacggtcag atctacctca atgaattaaa taccatgcct
    57661 ggctttacgc agtggtccat gtatcccttg ctctgggagc atatgggact gagctatgct
    57721 gagcttattg aggagctagt cagattagca caggaaatgt ttgaaaagcg tgaagggcat
    57781 ttaatataag agacaaagga cggaaggaga tatagcaatc ctctgtcctt tcgtttggcc
    57841 tgattggtag cgttttttgg tcagaagcct ttaaagccct atcgtctacg gttggctgtg
    57901 ccagctttag cctgtctatg aaggatcagc ctgtaggcat aaagtgaaat agaaagaata
    57961 ttcctaatat gttatgctat a
//
LOCUS       DARYYD010000005        56620 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.005, whole genome shotgun sequence.
ACCESSION   DARYYD010000005 DARYYD010000000
VERSION     DARYYD010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 56620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56620
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.005"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(378..2057)
                     /locus_tag="TV188_000237"
     CDS             complement(378..2057)
                     /locus_tag="TV188_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533635.1"
                     /translation="MTKKVASLVLIGLDSLILAGFYWIYLPPMNVMSLEFWFFVILAL
                     ILAMVSLFILSLFGLKKTVTSFFTQKSGRKDVTSGLSLKQLTGGIKWLGLALAVIIAG
                     LSLLLAVNTRMFRAKSYAHVIKVKDADFNKDFPDTDLSALALLDRDSAEKIGDTYLGT
                     IDKVSQFGISDEYRQITIGKLPYRVSPLEYKSFWKWLTNRKDGIGYYVKVNQTTGKAE
                     LVKLNQPMKYSHSEFMFRDTMRHLRFQYPMTIFSDPSFEVDDDGNPYYVATTYAPKFG
                     LSSQEPTGVILLDAVSGKSQYYELKDVPKWVDRVYSADNVLERVNDYYTYQKGYWNTV
                     FSQTDVKQTTDSYNYITIGSDIYLYTGITSATADSSNLGFILVNMRTREVTNYKLPSA
                     TEASAMKSAEGEVQEKKYTATAPTLVKLNDKAYYLISLKDGAGLIKSYALVDAEDYQQ
                     VTVNNDIQTLISQFTDKDTSSLSVSDTNDQKVKMITGQVEQLASQIISGTTVYYISSK
                     GQIYKIKASSETSDRLPFLKVGDQFKAQLADDNYLNHMTIESSSADQAITE"
     gene            complement(2232..7136)
                     /locus_tag="TV188_000238"
     CDS             complement(2232..7136)
                     /locus_tag="TV188_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1533636.1"
                     /translation="MEKKERFSLRKYKSGMVSVLIGILFLTGMGSVVAEEQGVSSAHV
                     SAGQHQESREVLSVSQASEGAAVNAQDIDSQSSKAEEKTEEAMATGLVSSEMEALTES
                     NQSVKQQEESRELPPVNMDTHRWIKTEGAWNRGYKGQGKVIAVIDTGIDASHHAMRIT
                     NPAAAKFTSKADIDQRKKAAGIQYGVWLSDKVVFAHNYVENNDKVKEIKDDPFEGLDD
                     LDFDVIVQQIDIRRNRPQSIEAPQETVIKLDDTSGGTIIDWQDTDDDSKYESHGMHVT
                     GIAAGNGLKAAAAGERFLGIAPEAQVMFMRVFTHDLMGTGDPLFIKAIEDAVALGADV
                     INLSLGSANGSQLNGNRALMAAIEKARQAGVSVVVAAGNERAFGSDHADPLVTNPDYG
                     LVGAPSAGRTPTSVASINNKVIIERLMTVEGLKDRADLNHGKAIYLESVDFKDIKTSL
                     GFDVPYSFVYVKALTKEGYQEREVSGKIVLVQRDPNRKYDDIIAEAKQYGAAGVLIFN
                     NEPGKANRTMRLSSKGMVLPSAFISHEFGMAMAALNGNGTGTLTFDAEVSKAISQKGN
                     EMNYFSNWGLTSDGYLKPDITAPGGDIYSTFNDDHYGSQSGTSMATPHIAGASLLVKQ
                     YLEALQPQLAKDKLADLVKNILMSNAQIHINPKTNTTTSPRQQGAGLLNIETAVTSGL
                     YLTGKDNYGSISLGNVTDQISFEVTIHNLSNQAKSLRYQTELLTDQVDTKEGRFALRS
                     RSLKTYQGEQVDVPAQGHKTITITLDASNFTEELSKQMPNGYYLEGFVRFVDSKDEHK
                     DNINIPFVGFKGAFENLPVVEASIYELKAQGKTGFYFDSSGLKDEIYVGNHFTGLVTV
                     GTDTNVSMTTIADNGLHTLGTFRNKDGKFVLERNAVGYPVLAISPNGDNNQDFAAFKG
                     VFLRKYQGLQARVYKGTDTDRKELLWTSPSALQGDKNFNSDIRFAKSTTLLETGFSGK
                     SLTGADLPDGKYHYVVSYYPDVVGAKRQEMVFEVIVDRQTPELGTASYNPVTHRFRPS
                     QWLDRGQAGVLRDSVFYLETKDDKPYTITINDGLKYVTVSDNKQFVERLADGSFVLPV
                     DQVALGDFYYMVEDFAGNVAIAKLGNHLPEKIGQAELALTLTDINAQHQLSYSDNLNM
                     TAADTGLVTNEAELLIISRNRPQSRLAKLGQTAVISPNDDGNKDFVAFKGLPHQVYQD
                     LKVTVFAQEDTAMTSPIWSSQPGASVANVDSTAWYGTRASGARVMSGHYRYVVSYLDA
                     NGMPQAEAYAVTVSHQKPVITPASFQADGATEVFRPGPSKGQSPIGIVREEVFYLVKK
                     DGRKFDLTVEDQLIRFKDNKVMIAQNADGTYTIPKVEGVAEADYYYLVEDEAGQIAYM
                     SLAALRAVGPDKGVVSVALALDVLENKKEPAFTYLIRDEQGKPIEQLDYFNSSANSLI
                     LPFGRYTVELLAYDNHLFELRSDNLVSFSLDADTRLASVAFEMTRPIVASVWLLFNQV
                     LPEGSRVSLKAANGQLISLAPSLYVPSAYGKTLRQGSYEVLVELPEGYQLIGQGGLEV
                     SHNGVIELTFEVIKAKQPQLEHQAGGLTHYTGSSITSSALTAQAVKKAQVLPSTGEQA
                     AVNLVLLGLLSLGAAGSCQRQKKY"
     gene            7489..8316
                     /locus_tag="TV188_000239"
     CDS             7489..8316
                     /locus_tag="TV188_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEL1533637.1"
                     /translation="MKLISWNIDSLNAALTGESPRALLSRAVLDTLVAQDADIIAIQE
                     TKLSAKGPTKKHLESLLGYFPNHLNVWRSSVEPARKGYAGTMFLYKKELNPIVTFPDI
                     GAPTTMDAEGRIITLEFNDFFVTQVYTPNAGDGLRRLEERQLWDQKYADYLAQLDAQK
                     PVLATGDYNVAHKEIDLANPASNHRSPGFTDEERLGFTNLLNRGFTDTFRFIHGDIPN
                     VYSWWAQRSKTSKLNNTGWRIDYWLTSNRLIDKVSRSEMISSGERQDHTPILLEIDL"
     gene            complement(8392..8745)
                     /locus_tag="TV188_000240"
     CDS             complement(8392..8745)
                     /locus_tag="TV188_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEL1533638.1"
                     /translation="MITIYQYPKCSTCQKALAELKTLVSEVDIIDIKANPPKAEQLKQ
                     WLEHSDYSLKSFFNTSGMRYRELGLKDKVNSLSVEEAAELLATDGMLIKRPILLQDNQ
                     VLQVGYRTAYKDLGL"
     gene            complement(8749..9261)
                     /locus_tag="TV188_000241"
     CDS             complement(8749..9261)
                     /locus_tag="TV188_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEL1533639.1"
                     /translation="MWGGQILPLYECVYQSPLGKISLVATDVALIGAWFEGQRYFQAG
                     IKVQPIWQEQHALLKRACLWLDAYFERKPYPMLDCLSPQGTDFQRAVWRELQTIRWGE
                     TLSYGELAKRLQCRSAQAVGGAIGRNPLSIFIPCHRVLAADGRLIGYAGGLEKKAWLL
                     RHEQISVNKE"
     gene            complement(9718..10272)
                     /locus_tag="TV188_000242"
     CDS             complement(9718..10272)
                     /locus_tag="TV188_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1533640.1"
                     /translation="MEIRLAFPNELSQIMTVINSAKSALAQSGSSQWQKADGYPAYQD
                     IAADVLQGQGYVALLEGQIVAYAAVIDGQEDAYDKIYDGRWQHNHHRYVTFHRVAVLS
                     DRTGQGIAQTFLQGLIEGQHGPDFRIDTHEHNQVMRHIIEKLGFVYCGKVPIDGERLA
                     YQKIKKSHERAAYQEISEDSRYSY"
     gene            10483..11112
                     /locus_tag="TV188_000243"
     CDS             10483..11112
                     /locus_tag="TV188_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEL1533641.1"
                     /translation="MIKEFCAENLTMLNQLTSQSVNRVELCDNLAVGGTTPSYGVIKE
                     ACDLLHDKQISVATMIRPRGGDFVYNDLELRAMEADILKAIEAGTDALVIGLLTKDNQ
                     LDTDAIEQLLPATQGLPLVFHMAFDLIARDQQIASLEQLIDYGFVRILLHGSSDTRSI
                     YENIDHIKQLVKAAQHRIEIMIGGGVTADNCQELSQLTGTAIVHGTKII"
     gene            11571..12656
                     /locus_tag="TV188_000244"
     CDS             11571..12656
                     /locus_tag="TV188_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533642.1"
                     /translation="MTTRYFYKLLLTMLTLALGGFSLSACHSKISKPYQVAIFDKDHV
                     RTFMEKADSLVPVETISRTQHKLFERESFKQAKQGYFAKTREGNDLKVLLTHIDQASL
                     EEKVLHADGNDAYTSTTDGDYFYTTAVFADRIDCYKYDRHLKKQAHKSILNQDTINAS
                     NQFLVIDDALYLLVSAVDIKSQQPKTELWKMDKSFTITDRIDLDESTAYLRMVNVGRT
                     LYITQAADGILETGEPRPGNKVMTYDLDSGQKSYLMLHVNSPRAIYHHAKTNELIIEN
                     DQHYNPDFAWTIYQLDTGEERTIRFEELAGQETSSPYFMMTSSNYYFLFPKRLYRYDC
                     SNHQMTCINLDQYGVTHAHALIAKPTP"
     gene            12842..14053
                     /locus_tag="TV188_000245"
     CDS             12842..14053
                     /locus_tag="TV188_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1533643.1"
                     /translation="MYESPEKIPYQLPLYDKYEGNNSLFRDNASPNFRADVKDITATL
                     VAVLSNGYPTGKSSFCKDYCPDEIRARQLTQLAIWYFTDGISEETLKSNYSLNDLEFQ
                     GLKYLIQAGKTAGTSNNRTLDIYISKDRNSKFQNLLGSTLVVKTPENKENCQCTKIYI
                     EENGKDGYYLYIYEDTNKNDKYDKNKDKLLQKKYIKNGKDGKPGLNGQRGPQGEPGKQ
                     GPQGPRGDKGETGEKGQDGKPGKQGDRGPAGPQGPRGDKGETGEKGDPGRNGKDGKPG
                     EKGDPGQQGIPGPKGDPGKDGEKGERGEQGPRGENPTPTPDPMPQPMPDPAPKPESKP
                     EPKPIPQPEVKPQPETKPQQPNKPSTITSQPSGKALPKTNDTGSLITVLGTGLLSLLG
                     LGFLTRRKRKQ"
     gene            14364..15455
                     /locus_tag="TV188_000246"
     CDS             14364..15455
                     /locus_tag="TV188_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1533644.1"
                     /translation="MRKTMKKMLAASTVCIIMSGSFIGGAARVLAEQYYGYDDGTKDG
                     GDWPVFLYVTPTNHPERKTDKEHCVYCFNRLNSSPELWESQFKDPSKLGIKLPIYEKK
                     EGDESLLRAKSQKPSDNLTSKLVTVLSNGYPNKTLGNLSEDQSRRLTQLAIWHFTDGY
                     ATNHFKDGYHLNKDEDSELKKLIETAEKNFQTTAHTYSLNLYVTSSYNYSTGKFYQHL
                     LGSTLTPKLPNPNPGPKPPGGNNPHHLPGENGQTKYPEGESGEAGAPKKPEPKPEPKP
                     EPMPKPEPKPQPEPMPEPKPKPEPQPKPAPQPEVKPQKPTKPSNTTSQSSGKGLPRTN
                     EAGSLMTGLGTGLLSLLGLGFLTRRKRKD"
     gene            complement(15588..16706)
                     /locus_tag="TV188_000247"
     CDS             complement(15588..16706)
                     /locus_tag="TV188_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533645.1"
                     /translation="MIPFIKALFIKIRRKKTSYITFILLPMLTTMLALSLSFTGGSQA
                     KIGILDKDKSQVSKQFVSQLKHNKKYQIYTRLEEKAIDQYLKAKTLEAVLTIEPGFGE
                     KVLKGDTQKIALRSIADSQITEWFKAQANYLLENYNIIGDAAAGNQEVFKKISAHNTK
                     LSYKVKEITLADRSQSKSVSSTTTGFLLILMLGSTSVLYGGILLDKSSQIYNRLVLSR
                     LSSLQYMLSYVCVGIVAFAIQIVIMLGLLRVANVSFYIPTAIVLLTFFLYSLLAIGFG
                     LMIGAVSKNAQQSSQLANLIVMPTSMLAGCLWPLSITPPYMQAIGKLLPQHWVLTIIS
                     TFQNGGNLGEAWPYFLALFVAAMTLMVLASVLMKPLHR"
     gene            complement(16703..17830)
                     /locus_tag="TV188_000248"
     CDS             complement(16703..17830)
                     /locus_tag="TV188_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533646.1"
                     /translation="MILFHLIKKESLQIFRDRTALLMMVVFPILMILILSFAFKSSFN
                     TAATVPKLTVRYQLEGKETEYQKNFITFLKLLNKELHLEAKETKDIAKAKQKVSEGAL
                     TAALEVKSDQNIEVTTNSINQQNADLINMLVNIYVDNAKTYDSIANLYPEAISNIKKR
                     KIDYIASSSVQTSKGMSSADYYAISMFTMITFYSIMSAMNLVLSDRQQGVASRIYLTG
                     VSNSAILLGKLIGGMLATAVQLTILYVFTRFVLRVNWGTNDWQIIGVTASLVYLSVAI
                     GIGLATGIRNQSFLTVASNAVIPVFAFLGGSYIPLSTLNSALINQLSNISPIKWVNDS
                     LFYLIFGGQSNPIPVTLMVNLGIGTAFILFALVRMRKQVAA"
     gene            complement(17839..18762)
                     /locus_tag="TV188_000249"
     CDS             complement(17839..18762)
                     /locus_tag="TV188_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533647.1"
                     /translation="MSFVELKDVVKVYRGGKKAIDHVSLTIEEGRIYGLLGPNGAGKS
                     TLINAILGLIPLNAGEVTVLQQSYKSIRKISSKIGYVPQDIAVYPDLTAYENVELFGS
                     LYGLKGSELKEQVLKSLEFVGLKSQASQFPSQFSGGMKRRLNIACALVHSPKLIIFDE
                     PTVGIDPQSRNHILESIRLLNEQGATVIYTTHYMEEVEALCDYIYIMDHGQVIEEGSQ
                     AELERRYESDFTKQIMVTVAADQAIDLSNKPNWRLMDNELEAVLLIEHEDIGSVVRQL
                     TDAHIAFSEIRHKHLNLEEIFLHLTGKKLRD"
     gene            complement(18785..19471)
                     /locus_tag="TV188_000250"
     CDS             complement(18785..19471)
                     /locus_tag="TV188_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagF"
                     /protein_id="HEL1533648.1"
                     /translation="MIIILALLSFLILVTLFLTSHKRRRLVRWHLRHIRAMSYQQWLD
                     LLLGLIQLGLVLVCLLFSDALALDGLLTFLGRVSFGWEIICYVLLYSIALVELTLLVL
                     VLLFDLMLKKDSRLLLGKMTWLAFKPDRAAASFLLLSLVTLVDAFCYLGLCLFLGKDS
                     VAGLTLVVLGYALVKACRYSGWLQQLLALCLFSVIGVWCVTAALLYGWLIGSLLLTLT
                     YLLISFKEQR"
     gene            complement(19468..20139)
                     /locus_tag="TV188_000251"
     CDS             complement(19468..20139)
                     /locus_tag="TV188_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEL1533649.1"
                     /translation="MPLYTQCLNLCFLMATFCPSIAMQAIFGQGRDSYSFNLIGFLRA
                     VLVYYALVLTGIYLLSPPIKAPLGHSDGRLLIIGFILSFVVLFVEVAFLHLSRCWQKK
                     EWLPLVLSFVGTTQKWPQIGYPLVLACCEEITYRLIWFNILWLQWRLPIALVLLITSL
                     CYALNHFLMGRSIFYAKILTGLIYGSIYYVSQSLWLVLLVHVGGNLWVEGLSHLQSMH
                     KKVVR"
     gene            complement(20114..21472)
                     /locus_tag="TV188_000252"
     CDS             complement(20114..21472)
                     /locus_tag="TV188_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HEL1533650.1"
                     /translation="MLHYYPSFNHILDKLKGLSGNRTGILNQSQVPICNHPHDVYLKS
                     VTGQMPDYHKQFIGELSQVSYHIIGYGSHYEEALIKYLGESIERYATVIAGELLSDRI
                     VYASYKELSQTDPVMPLEYLQVFTQEQIDRCHDLHMIMCDKMVTQDDVLGWVKCPMFF
                     EDKEMYVPAQMLCVGYKTNQAVGEKHIIPGFSTGTASHTTLEAAMCNSLIEYIQIDSM
                     MLSWHTKKPCPRVIIDDPEILALLEEARLGKDSLYEIIPIDMTVGEDNPLYTFGIILK
                     NKSNEGPYLLFGVQAGLDPKHTLLRGIMEASAISYSYYYNLFYNPTSTQNAESDSPLF
                     LDLDSNVFYYAHPKDQELKWKAFEPLISGEVRLSDLTNHAGKDKKEDLKTLLAYTKKV
                     SPNAVFLDITPPEASEKGWYVTRVLTPELLEMCIPAFPFANHPRMRQFGGVTNAFVHP
                     MP"
     gene            complement(21485..22549)
                     /locus_tag="TV188_000253"
     CDS             complement(21485..22549)
                     /locus_tag="TV188_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin associated protein SagC"
                     /protein_id="HEL1533651.1"
                     /translation="MKYQLNSNVRIVQFDDTFCFRKGLWDFNEAVLDIAQEPQALKEA
                     YYSIISDWFNGKVIDTDTYEKTLESDLFAKLSEVITALYYNDLLMLEDAYALEENIMK
                     VLTGNYHFIAESGQAKDTAPVLFISDSSYVNESAELLAKHLNLNLQVASDELKMLIQE
                     TDVTSRLDALEHHRNMKCLSEKLADYQSIVICQGRLNIMMLRHLNEISVALKKQLVLG
                     FVDGPFIHACTLNPPHSADFDSLERRVLARLQDHTLYQRFASQQLPPTQPVSSSYVPL
                     LNVLMNLVVSEAFIIAQTGSSKFEGRLLSVYLPTLEIQVQDILKMSNSQTQGALTKLR
                     YEDQQISTREIVKKLLQEES"
     gene            complement(22546..23496)
                     /locus_tag="TV188_000254"
     CDS             complement(22546..23496)
                     /locus_tag="TV188_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SagB family peptide dehydrogenase"
                     /protein_id="HEL1533652.1"
                     /translation="MPFFSKEKQRSDNQSDLTREEARQLFEFNTNHLSLSTYHHQTVL
                     KTSKQLVAQHLMPDETDNLSQRFLMNYKANNNYLGFKTSVAEFFTDSAVTTFSNSDYF
                     EDRANTIALPKAKKVSAALSTCITNRRSHRQFIDEEMPLQDLADLLYYACGVSSQAII
                     KEGMTKTVALRNCASGGGLYPITLFFYARNVETLKDGFYEYLPYQHALRCHHLSDQED
                     IRAFAEYGPITAENCNVILIYVYQYIKNTRKYGNQATAYAFIEAGEIAQNVQLVSTAL
                     VYGSVDIGGYNKEYLQEKLGLDGLTQHVIHMTIIGNKESQ"
     gene            complement(23724..23888)
                     /locus_tag="TV188_000255"
     CDS             complement(23724..23888)
                     /locus_tag="TV188_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptolysin S family TOMM toxin"
                     /protein_id="HEL1533653.1"
                     /translation="MLQFASNILATSVAETTQVAPGGCCCCCSCCCCVSASWGNTTIN
                     NNYGAAEPKA"
     gene            complement(24417..24674)
                     /locus_tag="TV188_000256"
     CDS             complement(24417..24674)
                     /locus_tag="TV188_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEL1533654.1"
                     /translation="MDPKKIARINELAKKKKTVGLTGPEKVEQAKLREEYIEGYRRSV
                     RHHIEGIKIVDEDGNDVTPEKLRQVQREKGLHGRSLDDPES"
     gene            complement(25211..27250)
                     /locus_tag="TV188_000257"
     CDS             complement(25211..27250)
                     /locus_tag="TV188_000257"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014712716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEL1533655.1"
                     /translation="MTKDLLVELGLEELPAYVVTPSEKQLVERMADFLKANRLSYDAI
                     EGFSTPRRLAVRVLGLADQQTDLTEDFKGPSKKIALDADGQFSKAAQGFVRGKGLTVD
                     DIEFREVKGEEYVYVTKHEAGKQAKDVLAAVPEVLASLTFPVSMHWANNSFDYIRPVH
                     SLIVLLDDEPLELDFLDIHSGRISRGHRFLGEETSITSADSYEADLRSQFVIASAKER
                     QEMIIAQIRAIEAEQKVQVDIDEDLLNEVLNLVEYPTAFMGSFDPKYLEIPEEVLVTS
                     MKNHQRYFVVRDQAGKLMPNFISVRNGNAKHLQNVIKGNEKVLVARLEDGEFFWREDQ
                     KLSIEDLVAKLAHVTFHEKIGSVAEHMERTKVIAAFLADQAGLSEAEKSAVARAAQIY
                     KFDLLTGMVGEFDELQGIMGEKYALLTGEAAAVATAIREHYLPNSAEGELPETKVGAV
                     LALADKLDTLLSFFSVGLIPSGSNDPYALRRATQGIVRILEHFGWSIPMDKLIDSLYE
                     LSFDSLTYQHKAEVLDFICARVDKMMGSAIPKDIREAVLASSSFVVPELLARAEALAA
                     ASQLDTYKPAVESLSRVFNLAKKAVDAVLIDASLFENDYERALAQAVDSLVLSGSAKE
                     QLAQVFALSPVIDDFFDHTMVMTEDEAIRRNRLALLAELVKKVETIAAFDRLNTK"
     gene            complement(27616..28527)
                     /gene="glyQ"
                     /locus_tag="TV188_000258"
     CDS             complement(27616..28527)
                     /gene="glyQ"
                     /locus_tag="TV188_000258"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEL1533656.1"
                     /translation="MSNKLTFQEIILTLQQYWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLQSLER
                     LGIDPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWAPGVKYGEIFLQPEYEHSKYSFEVSNQDMLLENFE
                     IFEKEAERALAQGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRHLARSVA
                     KTFVAERKKLGFPLLDDASRVALLAED"
     gene            complement(28893..29426)
                     /locus_tag="TV188_000259"
     CDS             complement(28893..29426)
                     /locus_tag="TV188_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEL1533657.1"
                     /translation="MIILLLMLLMFAIRLVFLKKSIKNEKAILANGGKEFGAQNTKFL
                     TLLHIMIYVFAVTEALLKQIKFDGISFLGLLLMIFSIAVLYEVTRILGDIWTVKLMLA
                     KDHKYVDHWLFKTVKHPNYFLNIAPELVGIALLCHAQITAMLLFPCYIIVIYLRIREE
                     NRLLSEVIIPNGTRPKS"
     gene            complement(29693..29917)
                     /locus_tag="TV188_000260"
                     /pseudo
     CDS             complement(29693..29917)
                     /locus_tag="TV188_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515130.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(29947..30786)
                     /locus_tag="TV188_000261"
     CDS             complement(29947..30786)
                     /locus_tag="TV188_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEL1533658.1"
                     /translation="MIKTVTMANGLAIPVLGFGTFKAADGEEAYQSTLAAIKAGYRHI
                     DTAAIYHNEKSVGQAIRDSGVPREELFITTKLWNDAHSYDGAKAALAASLERLGLEYV
                     DLYLIHWPNPKALRDCWQAANAAAWSYMEEAVEAGLVRSIGVSNFMVHHLEALKQTAT
                     ITPAVNQIRLAPGCYQKETVDYCRRHHILLEAWGPLGQGEIFADDTMQALAKKYNKTV
                     AQLALAWSIAEGFIPLPKSVHKERIVENMAIFDCEISPEDSERIRCLPGMSAIPDPDT
                     KDF"
     gene            complement(30873..32021)
                     /gene="nagA"
                     /locus_tag="TV188_000262"
     CDS             complement(30873..32021)
                     /gene="nagA"
                     /locus_tag="TV188_000262"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEL1533659.1"
                     /translation="MTSYIKADCFYYPNEVKPAGYLELNNGTFGYWTATVDDQAEVID
                     YTGYQIAPGLVDTHIHGYAGADVMDNSAEGLHAISEGLLSTGVTSFLPTTLTSTFEHL
                     EQVSATVASVADQVKGAKIQGIYFEGPYFTEEYKGAQNPIYMKNPRLDEFAAWQKAAK
                     GLIKKIALAPERDGVEAFVSEVTKQGVTVALGHSNGTYTEAKKAVAAGASVWVHAYNG
                     MRGLTHREPGMVGAVYNIPGTVAELICDGHHVSPVACDILMQQKGHEHVALITDCMRA
                     GGSPDGDYMLGEFPVIVENGTARLKDSGNLAGSILKLKDGIKNVVAWGIASPAEAIHM
                     SSYVPAASVGIEDVCGQIKAGHAADFIVLDKDLELVATYLNGQKAFEA"
     gene            complement(32138..33779)
                     /locus_tag="TV188_000263"
                     /pseudo
     CDS             complement(32138..33779)
                     /locus_tag="TV188_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
     gene            33970..34716
                     /locus_tag="TV188_000264"
     CDS             33970..34716
                     /locus_tag="TV188_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533660.1"
                     /translation="MRKPTKETHYLIISLLTIAIAGGAYLIFSSLSPKPATITTQSKG
                     YELLTKAQALVKEAEDNPTKEAIAKAQKAINQLKKTQSKEELQARLTAISLKHNQEDV
                     AIKVLKAAEDNPSPELKEAAQKAISKLSDEAKKAALQARLDAIGLSKPSTAQPETATP
                     AAEKNIAPAPAAPQIKHTTPSSGGTTPAPNPKPSPKPNPQPSPSPAPENPEPTPSPNP
                     QPNPQPETNTPSPQPPATEQSENTAPAGQN"
     gene            complement(35322..36164)
                     /locus_tag="TV188_000265"
     CDS             complement(35322..36164)
                     /locus_tag="TV188_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1533661.1"
                     /translation="MTWKIVSDSGCDIRALKSQSNHLRFERVPLTLQIGSDIFRDDDG
                     LDIDQMMETMYQSSKPATSSCPSPDAFLQAYRGADNVIAITITGTLSGSHNSARLAQN
                     DLLEENPNANIHVIDSLSAGGEMDLIVLELERLINQGLSFDEVVEKITAYQEKTRLVF
                     VLAKVDNLVKNGRLNKLIGKVIGLLNIRMVGQASKEGTLELLQKARGQKKAVSAVLEE
                     IQKAGYKGGRVFISHAKNPKICEQIAEKIRAIYPEAEIQTSPASGLCSFYAEAEGLLM
                     GYEV"
     gene            36296..36853
                     /locus_tag="TV188_000266"
     CDS             36296..36853
                     /locus_tag="TV188_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1533662.1"
                     /translation="MAGKPISKQSLQNLAHCNQESRRLTREAIEIALLSLLEKKPLGH
                     ITISELVARAGVSRNAFYRNYSSKEDILECLLTSVIRRIFRGLKAFDLKTQAYQAWLY
                     LFTEAKKEATLLSIIFNHHLQQLLTQMVTKRLRAYQKWQEKKLSHYALLFWSNAIVSV
                     LSNWISDDMVVPAEEMAAMGLPLLA"
     gene            complement(37264..38088)
                     /locus_tag="TV188_000267"
     CDS             complement(37264..38088)
                     /locus_tag="TV188_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1533663.1"
                     /translation="MIQLIAIDLDGTLLDSKKHIPKENIKAIQAAAQEGIKVVLCTGR
                     PQSGTRPYFEQLGLSDKEEYLILNNGCSTYRSPSWELLHYQSLTFSAIEHLYQLSQPF
                     SDIYLTLTGERDYLVIDSKVPDMVQADGDLVFTKVKATNLSQLSNSSQIIFQAMYMGE
                     KAALDTFEALVREKLSASFSVVRSQETILEVMPECVTKASALKELTADLKLRPDQVMA
                     IGDAANDLEMLAYAGLGVAMGNADEAIKKVADKVSLSNDQAGVAHAINQFALTKGS"
     gene            complement(38093..38707)
                     /locus_tag="TV188_000268"
     CDS             complement(38093..38707)
                     /locus_tag="TV188_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HEL1533664.1"
                     /translation="MTIDMWELLSIIGTIAFALSGAIVAMEEEFDVLGIFILGFVTAF
                     GGGAIRNTLIGLPIEALWGQRPEFACAFIAIILIMLFPKLVAKGWVRAAVLTDAIGLA
                     AFSVQGALHAVRLAQPLSAVIVAAVLTGAGGGVVRDVLAGRKPTVLRSEIYAGWSIIA
                     ALVLYFKLATSNVECYLLVVLLTVMRMIGNKRQWHLPKIKWKED"
     gene            complement(38868..39740)
                     /locus_tag="TV188_000269"
     CDS             complement(38868..39740)
                     /locus_tag="TV188_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEL1533665.1"
                     /translation="MKKVMMSLLILATATLGACQASHQSDQPKQEQKEPQAKKGRLFL
                     SNMNSAKSQQEVRAALSHQLKEANVNAFMAGVQEYNSLVGKTGLTGAFTYQKQPDYDV
                     VAIDELWSQKQGNFIGTNCRINTFMLLKDSMTIAPTSSDDTLLFMDEDAITTSQLFTQ
                     AETERFKQLFSRVKTEATKDIQVHAKHMQEHFSAVSFNGPAKMLAVVIHDQLDGDYLF
                     IGHVGVLVEYKSKYLFVEKLSFQEPYQAILFDQKQDCYQYLYHKYKTYQTKTSAEPFL
                     MENNKAVNLASYRS"
     gene            complement(39951..40436)
                     /locus_tag="TV188_000270"
                     /pseudo
     CDS             complement(39951..40436)
                     /locus_tag="TV188_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515109.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
     gene            complement(40439..40705)
                     /locus_tag="TV188_000271"
                     /pseudo
     CDS             complement(40439..40705)
                     /locus_tag="TV188_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003106440.1"
                     /note="catalyzes the reversible reaction of
                     dihydroxyacetone phosphate with glyceraldehyde 3-phosphate
                     to produce tagatose 1,6-bisphosphate; in Streptococcus
                     pyogenes there are two paralogs of tagatose-bisphosphate
                     aldolase, encoded by lacD1 and lacD2; expression of lacD1
                     is highly regulated by environmental conditions while
                     lacD2 specializes in an efficient utilization of
                     carbohydrate sources; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
     gene            complement(40707..41639)
                     /locus_tag="TV188_000272"
     CDS             complement(40707..41639)
                     /locus_tag="TV188_000272"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEL1533666.1"
                     /translation="MILTVTLNPSIDISYPLNRLTLDTVNRVDRTTKTAGGKGLNVTR
                     VLAEAGQSVVATGFIGGKLGDFVIHQLQEQGISNQFFKIKGETRNCIAVLHEGMQTEI
                     LEAGPYIDMDEAEGFLNHMSIIAKQFDVLTFSGSLPKGLAAHYYQDLITMARVYGSKV
                     VLDCSGAPLKAVLAGKDKPTVIKPNLEELEDLIGQPVTLDEERLISLLSQPLFEGIEW
                     IIVSLGAQGAFAKHHNRFYRVTIPKIEVVNPVGSGDATVAGIAWALAEGDDDETLLKK
                     ANVLGMLNAQETRTGHVNMAHFDELFDRIQVEEV"
     gene            complement(41649..42164)
                     /gene="lacB"
                     /locus_tag="TV188_000273"
     CDS             complement(41649..42164)
                     /gene="lacB"
                     /locus_tag="TV188_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEL1533667.1"
                     /translation="MKIAIGCDHIVTDEKMAVSDFLKSKGYEVIDCGTYDHTRTHYPI
                     FGKRVGEAVANGLADLGVCICGTGVGITNAVNKVPGIRSALVRDMTTALYAKEELNAN
                     VIGFGGKITGELLMCDIIEAFIKADYKETEENKKLIAKIAHLESHNANQEDPDFFTEF
                     LDKWDRGDYHD"
     gene            complement(42180..42605)
                     /gene="lacA"
                     /locus_tag="TV188_000274"
     CDS             complement(42180..42605)
                     /gene="lacA"
                     /locus_tag="TV188_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEL1533668.1"
                     /translation="MTIILGADAHGNDLKEAIKGFLQQEGFDVTDVTAIADDFVDNTL
                     AVARALKADEESLGIMIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNARMIT
                     MGAEIVGQELAKNIAKGFVTGHYDGGRHQIRVDMLNKMA"
     gene            42741..43523
                     /locus_tag="TV188_000275"
     CDS             42741..43523
                     /locus_tag="TV188_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1533669.1"
                     /translation="MLKRERLLTIMEKVNANGFITVTDIMESLRVSDMTARRNLDELA
                     RAGKLVRIRGGAQSISMPQKLERSNTEKLTVQIEAKKEIARYASQLINDGETIFIGPG
                     TTLECLAEALINRHIRIITNSLPVFTILNKSKTVDLILIGGEYRAITGAFVGSLASQT
                     ILSLKFAKAFISCNGIYKNDIATYSENEGVIQRLACDNAIEKYLLADNQKFNAYDFYS
                     FYHLDNIDAIITDSKISDSVKERYRQFAKLLIARPADNQVSS"
     gene            complement(43939..44490)
                     /locus_tag="TV188_000276"
     CDS             complement(43939..44490)
                     /locus_tag="TV188_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1533670.1"
                     /translation="MSVTSSMLTLILCMTILWLIGVRNKLERYRIVIEESKRNVDIAL
                     EKRYDTISEMLKIAKSYAKHEEKVFTELVKLRQGLSLEETNDVMRTQEQALNEVFAVG
                     EAYPEMRSSEQFLSLQNEIAKENAALAAAKRIVNSNISLFNQAVVAFPVSIVASLINI
                     KQMTFLDIDLDHKKSLDQLDYTI"
     gene            complement(44503..45453)
                     /locus_tag="TV188_000277"
     CDS             complement(44503..45453)
                     /locus_tag="TV188_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3137 domain-containing protein"
                     /protein_id="HEL1533671.1"
                     /translation="MNENTKRLTDPIVLEKSRAIEASPEHHQKLEQIKSEMSGNARKN
                     NLGWLAMVIGAIILYGMVDRSLALFLIIFVGGLVWPRLKTFKTANELSYVDHFLLPVL
                     QEALPDVKIDYYSGIELSLLKLATPSSRWYDSNCHIIFGDDMQTEFCNLYAYHEENED
                     DNWHRVTDFNGQVLLAKYHTAIKGYIRIVPTQKGFLGREKVHSGYKAKLKGEVQLEME
                     DIRFNETYNVYCTDELSARMLLNPYMLAVLDEWREEMPVAVYMNGDTVVVSFYSGQQL
                     LKTPSSRGAIEKLSLSSEYENIQDKLVKMYRLLDTLNHQL"
     gene            complement(46324..48555)
                     /locus_tag="TV188_000278"
     CDS             complement(46324..48555)
                     /locus_tag="TV188_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HEL1533672.1"
                     /translation="MVKETYLLEGMHCTSCALAIEQAVKQLPGVEGAAVDVTTEKLSV
                     SYSTDSLSSAELIQAVRKAGYRAELLDETNMRGQLERLEEQASNEWYRFLWSALFSLP
                     LLYLAMGPMLGLVLPVALAPQSHAISYGLVQLLLTLPVLFLNRQYYENGFKALIKKRP
                     NMDSLVTLATSFAFIYSSYSCFKIVAGAAQFAHQLYFESVVVILTLITLGSYLEGRTK
                     GRASQAIQKLMSLRVTDVRVIREGALQLIPLEQVTNEDICFIQPGERVAVDGLIVEGQ
                     STVDESMLTGESLPVDKVTGDSVFAGTINGQGALRVKPSRLGNDTLLSQIIELVEQAQ
                     QAKAPIAALADRVSGVFVPIVLSLSLLSFLFWLFVMRESFDFALTIAIAVLIIACPCA
                     LGLATPTAIMVGSGRAAEQGILFKGGDILEKAYQVRTIVFDKTGTLTEGQAQLQRIIP
                     LAASEKQGLQEVASLEQYSQHPLGEALVRVAQEKGYDLLAVTDFQSLVGLGVTGVIDQ
                     HRLAVGNSELMSQQGIAISAAQTYAEQAALKGQTVVYYAKDNQLCALLLIADRLKADS
                     KAAIRALQDLGLQTVMLTGDNALTAQAIANEVGIDQVFSQVLPAQKAQIIADLKASGQ
                     LVAMVGDGINDAPALTLADIGISIGSGTDIAIEAADVILMTSAVRDVVECLELSRQTI
                     RVVKQNLFWAFSYNSLMIPVAMGILHVFGGPLLSPMLAGFAMSLSSISVVLNALRLRH
                     KKW"
     gene            complement(48555..48989)
                     /locus_tag="TV188_000279"
     CDS             complement(48555..48989)
                     /locus_tag="TV188_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEL1533673.1"
                     /translation="MDTISDAEWEVMRVVWANGSMKSSEIIAILHEKHHWSDSTVKTL
                     IGRLVKKKALRADRQGRSYIYQSLLDQDRRQLAMLRERLDGMCQRHHSRLLLALLKDT
                     PMTLEDIQAFQLLLEAKKVGAVSHVRCDCVPGQCHCQKKERI"
     gene            49219..50256
                     /locus_tag="TV188_000280"
     CDS             49219..50256
                     /locus_tag="TV188_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1533674.1"
                     /translation="MIKEKTLTYLKRQLILLALLLTAIGSQTIVQASTRSWKSWFIEQ
                     YFWLKRDKSYYAEQDENTFYNYVKSAGEKSNQGFNLTQNEVNGTLKTEYRDNMQVHSW
                     NENSTNPSNQKVILYLHGGSYLNNPTSYHIDMLKTLSTSLDAKIVLPIYPKAPTYTYD
                     VAMPRLVSLYQDILKSTNNNANNITIMGDSAGGGLALGLALALKNEDIKQPKDIILLS
                     PWLDVTLSNPEIPNYEASDPILSAWGLRIVGDIWARRGENNTKHPYVSPIYGDTSNLA
                     PITMFVGTHEIFYPDITKFDGMLKQKGHKHQLFVGEKMNHVYPIYPIEEAKTAQYQII
                     DTIKKEYEPQK"
     gene            complement(50328..50678)
                     /gene="rbfA"
                     /locus_tag="TV188_000281"
     CDS             complement(50328..50678)
                     /gene="rbfA"
                     /locus_tag="TV188_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEL1533675.1"
                     /translation="MTNHRIDRVGMEIKREVNEILHKKVRDPRVQGVTITEVQMLGDL
                     SVAKVYYTIMSDLASDNQKAEIGLKKATGTIKRELGKQLTMYKIPDLVFEKDNSIAYG
                     NKIDQLLRELEKKQ"
     gene            complement(50868..53738)
                     /gene="infB"
                     /locus_tag="TV188_000282"
     CDS             complement(50868..53738)
                     /gene="infB"
                     /locus_tag="TV188_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEL1533676.1"
                     /translation="MSKKRLHEIAKEIGKSSKEVVERAKSLGLDVKSHASSVEEADAN
                     KIASSFSAGVTKNVQAGSAKDKQVAEQKAKAAKATTPQPAASKAAEKPAAATQEASQP
                     VAVKPKSRNFKAEREARAKEQVARRQAGQNRSNDRKSDYRQLGRSQGQQTERAGHKSQ
                     NQQRDRRFDNRPSSGNNRNDGHRQAGNRDKNRSFNANSRQQDTGRQGQTQAGAPKIDF
                     KARAAALKAEQNAEYARQRESRFREQEEAKRLEQQARQEAKAAALKAQTEDKKHREAS
                     AKATESVASMAAASVAKPVDKRRKKQNRPDKGHDRDHGLEDGQKKNKKSWNSQNQVRN
                     QKNSNWNNNKKNKKGKHHKNSNTAPKPVTERKFHELPKEFEYSEGMTVAEIAKRIKRE
                     PAEIVKKLFMMGVMATQNQSLDGDTIELLMVDYGIEAKAKVEVDEADIERFFTDDSYL
                     NPENIVERAPVVTIMGHVDHGKTTLLDTLRNSRVATGEAGGITQHIGAYQIEEAGKKI
                     TFLDTPGHAAFTSMRARGASVTDITILIVAADDGVMPQTIEAINHSKAAGVPIIVAIN
                     KIDKPGANPERVISELAEHGIISTAWGGECEFVEISAKFNKNIDELLETVLLVAEVEE
                     LKADPTVRAIGTVIEARLDKGKGAVATLLVQQGTLHVQDPIVVGNTFGRVRAMTNDLG
                     RRVKSAEPSTPVSITGLNETPMAGDHFAVYADEKAARAAGEERAKRALLKQRQNTQRV
                     SLDNLFDTLKAGEIKTVNVIIKADVQGSVEALAASLLKIDVEGVRVNVVHSAVGAINE
                     SDVTLAEASNAVIIGFNVRPTPQARQQADTDDVEIRLHSIIYKVIEEVEEAMKGKLDP
                     EYQEKMLGEAIIRETFKVSKVGTIGGFMVVNGKVTRDSSVRVIRDSVVIFDGKLASLK
                     HYKDDVKEIGNAQEGGLMIEGFNDIKVDDTIEAYVMEEITRK"
     gene            complement(53758..54060)
                     /locus_tag="TV188_000283"
     CDS             complement(53758..54060)
                     /locus_tag="TV188_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEL1533677.1"
                     /translation="MNSLNRLSHLIGLAQRAKKVISGEELVIKAIRHQEVNLVFLAND
                     AGPNITKKVTDKSNYYNVEVSTVFSALELSAALGKPRKVVAIADAGFSKKMRTLMK"
     gene            complement(54053..54349)
                     /locus_tag="TV188_000284"
     CDS             complement(54053..54349)
                     /locus_tag="TV188_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEL1533678.1"
                     /translation="MPKVKKIPLRKSLVSGEIIDKRDLLRIVKNKEGQIFIDPTGKQN
                     GRGAYIKLDNQEALMAKKKQVFNRSFSMEVPESFYDEVIAHVDHKVKRRELGLE"
     gene            complement(54365..55519)
                     /gene="nusA"
                     /locus_tag="TV188_000285"
     CDS             complement(54365..55519)
                     /gene="nusA"
                     /locus_tag="TV188_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEL1533679.1"
                     /translation="MSKEMLEAFRILEEEKHIDKADIIEAVTESLKSAYKRRYGQAES
                     CVIEFNDKTADFQVFTVREVVEEVFDSRLEISLNDALAISSAYELGDKIRFEESVSEF
                     GRVAAQSAKQTIMERMRRQMREITFNEYKQHEGEIMTGTVERFDQRFIYVNLGSLEAQ
                     LSHQDQIPGETFKSHDRIDVYVYKVENNPKGVNVFVSRSHPEFIKRIMEQEIPEVFDG
                     TVEIMSVSREAGDRTKVAVRSHNPNVDAIGTIVGRGGSNIKKVISKFHPKRYDAKTGL
                     EIPVEENIDVIQWVDDPAEFIYNAIAPAEVDMVLFDDDDLKRATVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEYERLEAEKEAAMTEAVATEELLTNEEV"
     gene            complement(55629..56111)
                     /gene="rimP"
                     /locus_tag="TV188_000286"
     CDS             complement(55629..56111)
                     /gene="rimP"
                     /locus_tag="TV188_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEL1533680.1"
                     /translation="MNIANTAIIDIVTQIVEPVIKAPYELVDIEYDKMGNDYVLSILV
                     DKASGITVEDTAELTELISPLLDTISPDPFPDQYMLEVSSPGLERPLKTAESLKAAVG
                     SYINVSLYRAIDKVKVFQGDLVAFDGDTLTIDYLDKTRHKTVEIPYQAVAKARLAVKL
                     "
BASE COUNT        16493 a        13522 c        10916 g        15689 t
ORIGIN      
        1 tttaattttt ctgaaaaacc agtagataag gcattttaag cattttttga tgataagata
       61 atatcacaaa acattaatta tatgacaatt attgttttta attattagaa tttttaatca
      121 aaactatcct gcaatcagct gtttagccat tttaaaaggc aaacaaaaac catgccacat
      181 tgcaatgaca tggttttctt caagaaagga gcgagctttg gtttggtact ttctacaact
      241 gatctccaat agcagctgct cctcgttagt ccctgagcca caggtgactg agctttcctg
      301 cggctactct gatagtacca gctactctta caactgcata aagcagtggc tgccagccaa
      361 gctaaagcta aacaatatta ctctgttata gcttggtctg ctgacgagct ctcaatggtc
      421 atgtgattga ggtagttgtc atcagccagc tgagccttaa actggtctcc gacctttagg
      481 aaaggcagac ggtcactagt ttcactgctt gccttgattt tataaatctg acccttggag
      541 gaaatgtaat aaaccgttgt tcctgagata atctggctgg ccaattgctc cacctgccca
      601 gtaatcatct tgaccttctg atcattggtg tctgacactg acagcgagct tgtgtcctta
      661 tctgtgaatt gtgagattaa ggtctgaatg tcattattca ctgttacctg ctgataatcc
      721 tctgcatcaa ccaaggcata ggattttatc agaccagccc cgtccttcaa tgagataagg
      781 taataagcct tgtcatttaa cttgactagg gttggtgcag ttgcagtgta tttcttctct
      841 tgaacttcgc cctcggctga tttcatggca gaggcctctg ttgcagaagg cagcttatag
      901 ttagtgacct ctctggtacg catgttaacc aaaataaagc cgagatttga cgaatcagct
      961 gttgctgagg tgattcctgt atagaggtaa atgtctgagc cgatggtaat gtagttatag
     1021 ctgtctgttg tttgcttgac atctgtctgg ctaaagacag tgttccaata gcccttttga
     1081 taggtgtaat agtcattaac cctctccaaa acattgtcag cagaatagac acgatcaacc
     1141 cattttggaa cgtcctttag ctcatagtat tgagacttgc cgctaaccgc gtctaacagg
     1201 atcacacccg tcggctcctg agaggacagg ccaaattttg gggcgtaggt tgttgcgaca
     1261 tagtaagggt taccatcgtc atcaacctca aatgacgggt ctgaaaaaat ggtcatcggg
     1321 tactggaagc gcaaatgcct catggtgtct ctaaacataa attccgaatg agaatacttc
     1381 ataggctgat ttaacttgac tagctctgcc ttaccagttg tctgattgac cttgacataa
     1441 tagccaatgc cgtccttacg attggttagc catttccaga aggatttgta ctccaaggga
     1501 gaaacacgat aagggagctt gccgatcgta atctgacggt actcatcaga aataccaaac
     1561 tgcgatacct tatcaatggt cccaagataa gtatctccaa tcttttcagc cgaatctcga
     1621 tccagcaatg ccaaggctga cagatcagtg tctggaaaat ccttgttaaa atcagcgtcc
     1681 tttaccttaa tcacatgagc ataggactta gcacgaaaca ttctagtatt aacagctaac
     1741 agcaaggaca agccagcaat gataacagca agggcaagac caagccactt tatgccaccg
     1801 gttaattgct tgagtgaaag acctgaggtc acgtccttgc ggccagactt ttgcgtgaaa
     1861 aagctggtca ctgttttttt caacccaaac aaggacagga taaaaagact caccatcgcc
     1921 aagataagcg caagaatcac gaaaaaccaa aattctaagc tcatcacgtt cattggcggc
     1981 aaataaatcc agtaaaagcc agccaggatc aagctgtcta agccaatcag caccaaagaa
     2041 gcaacttttt ttgtcatact aatctcctcg tcacacccta aggctatcag gggtattcaa
     2101 tatcttctca ccgctattgt accacatttc ccctcaaaag atgacatctc agccagacat
     2161 ttttatcagc tcttagagca cctcagctag aatgatcaat acagctgaca ggctacgctc
     2221 atagagcttg cttagtactt cttttgacgc tggcaagagc ctgctgctcc aagactgagc
     2281 aagcctagca ggactagatt gaccgctgct tgctcacccg ttgatggtag gacttgggct
     2341 tttttaactg cttgtgctgt tagggcagag ctagtgattg atgagccggt ataatgagtc
     2401 aagcctccag cctgatgttc tagctgaggc tgcttagctt tgataacctc aaaggtaagc
     2461 tcaatcacgc cattatgtga tacctctaga cctccttgac cgattagctg atagccctcc
     2521 ggtagctcaa cgaggacctc atagcttcct tgtcgcagtg ttttaccata ggcacttgga
     2581 acatagagag acggagctag agaaatcaac tgaccatttg ctgctttcag gctgaccctg
     2641 ctgccttctg gcaagacttg gttaaacaag agccaaacag aagccacaat aggccttgtc
     2701 atctcaaagg caactgaagc aagccttgta tccgcatcta gactaaagct aaccaagttg
     2761 tcagacctta gctcaaacag atgattatca taagccaaga gctcaacggt gtagcgtcca
     2821 aatggcaata tcaagctatt agctgagcta ttgaaatagt ccaactgctc gattggcttg
     2881 ccctgctcat cacgaataag ataagtaaag gctggctctt ttttgttctc aagcacatca
     2941 agtgccaagg caacggacac tactcccttg tctggtccta cagctcgcaa agcagctaag
     3001 ctcatataag caatctgacc tgcctcgtct tccactagat aataataatc tgcttctgca
     3061 acgccttcaa ccttaggaat ggtgtaggtg ccgtctgcat tttgagcaat catcacctta
     3121 ttatccttga atctgatcag ctgatcttcg acagttagat caaacttgcg tccatctttc
     3181 ttgacaaggt agaagacctc ttctctaaca atacctattg gactttgtcc cttgcttggt
     3241 cccggacgaa agacctcagt agcaccatca gcttggaagc tagctggcgt aatgactggc
     3301 ttttgatggc taactgtcac cgcataggcc tctgcttgag gcataccatt agcgtctaga
     3361 taagaaacaa catagcgata atgtcctgac atcaccctag ctcctgaggc tcttgtgcca
     3421 taccaagcgg tgctgtcaac attagccacg cttgcacctg gttggctaga ccagattggg
     3481 cttgtcatag ctgtatcctc ctgggcaaag accgttacct ttagatcttg atatacttga
     3541 tgtggcaagc ccttgaatgc cacaaaatcc ttgtttccat catcattcgg cgagatgaca
     3601 gcagtttgac ctaatttagc caaacgactc tgtggtctat tgcggctaat aatgagaagc
     3661 tctgcttcat ttgtcaccag tcctgtatct gcagcagtca tgttgaggtt atcactgtag
     3721 ctcagctgat gctgagcatt aatatcagtt agggtcaatg ccagctcagc ctgaccgatt
     3781 ttttctggca agtgatttcc cagcttagca atggcaacat tgcctgcaaa atcctcgacc
     3841 atgtaataaa aatcaccaag cgccacctga tcaactggca ggacaaaaga gccatctgct
     3901 aagcgctcaa caaactgctt attgtctgat acggtcacat actttaagcc atcattaatg
     3961 gtaatcgtat aaggcttgtc atcctttgtt tccaagtaaa aaacactatc tcgaagaaca
     4021 ccagcctgac cgcgatcaag ccactgagac ggtctgaagc gatgggtcac agggttatag
     4081 cttgctgttc ctagctccgg cgtttgacga tccacaatca cctcaaagac catttcttga
     4141 cgtttcgctc ctaccacatc tggataataa gaaaccacat aatggtattt gccatctggt
     4201 aggtcagctc cggtcagcga tttaccacta aagcctgttt ctaacagcgt tgttgacttg
     4261 gcaaagcgaa tatcactgtt aaagttttta tccccttgaa gggctgatgg gctcgtccag
     4321 agcaactcct tacggtctgt atctgttccc ttatagaccc tggcttgcag gccttggtat
     4381 ttacgtaaga acaccccttt gaaggcagca aagtcttgat tgttgtcgcc atttggagag
     4441 atagccaaca caggatagcc aactgcattt cgctccaaca caaatttacc gtctttatta
     4501 cgaaaggttc ctagtgtgtg caagccattg tcagcaatag tagtcataga gacattggta
     4561 tctgtaccaa cagtcaccag cccagtaaaa tgattgccga cataaatctc gtcctttagc
     4621 cctgagctgt caaaataaaa gccagttttt ccttgagcct ttagctcata aatagaggct
     4681 tcaacaacag gtaggttttc aaaggctccc ttaaagccaa caaatggaat gttgatgtta
     4741 tccttgtgct cgtccttgct atccacaaag cgaacaaagc cctctagata atagccattt
     4801 ggcatttgct tagagagttc ctctgtaaag tttgaggcat ctagggtaat ggtaatggtc
     4861 ttgtgtcctt gagcaggtac gtcaacctgt tctccctgat aggttttcag agatcttgaa
     4921 cgtaaggcaa aacgtccttc cttagtatcc acctgatcag tcaacaattc tgtctggtag
     4981 cgcagcgact tagcctgatt agacaagtta tggattgtca cctcaaagct tatctgatca
     5041 gtcacatttc caagagaaat actgccatag ttgtctttac ctgtcaggta cagaccactg
     5101 gttaccgcgg tctctatatt caagagccct gctccctgct ggcgtggcga tgtggtggta
     5161 ttggtcttag ggttgatgtg gatctgagca ttactcatca gtatattttt gaccagatct
     5221 gctagcttat ccttggcaag ctgtggttga agcgcttcta gatattgctt gaccaaaagg
     5281 cttgcccctg caatgtgtgg ggttgccata ctagttcctg actggctgcc atagtgatca
     5341 tcgttgaagg tcgagtaaat atctccacct ggagcagtga tgtcaggctt caaatagcca
     5401 tctgaggtca agccccagtt agagaaatag ttcatctcat ttcccttttg gctaatggcc
     5461 ttagagacct cagcatcaaa ggtcagagtg cctgttccat tgccatttaa agcagccatt
     5521 gccatgccaa attcatgaga gataaaggca gatggcagca ccatcccctt tgaactcaga
     5581 cgcatggtgc ggttagcctt gcctggctca ttgttaaaaa tcaagacccc agctgccccg
     5641 tactgcttgg cctctgctat aatatcgtcg tatttccgat taggatcacg ctgcaccaag
     5701 acaatcttgc cactcacttc gcgttcttgg tagccttctt ttgtcaaagc tttgacataa
     5761 acaaatgagt atggtacatc aaagccaaga ctagtcttaa tgtccttgaa atcaacagat
     5821 tccaaataga tagcctttcc atgatttaag tcagccctat ctttcaagcc ctccaccgtc
     5881 atcagacgct ctataatcac tttgttatta atagacgcaa ctgaggtagg agtccggcct
     5941 gctgatggag cccccactaa gccataatca ggatttgtca ccaacgggtc tgcatgatct
     6001 gacccaaagg cacgctcatt acctgcagca acgaccacag agacaccagc ctgccttgcc
     6061 ttttcgatag ctgccatcag ggcacgattc ccattcaatt gagacccatt ggccgagccc
     6121 agacttaaat taatcacatc agcgcccaat gccacagcat cttcgatggc tttaataaat
     6181 aaggggtccc cagttcccat caaatcatgg gtaaaaaccc gcataaacat gacctgagcc
     6241 tcaggagcaa tgcctaaaaa gcgttcgcca gctgctgccg ccttgagccc atttccagct
     6301 gcaatgcctg tcacatgcat gccatgcgat tcatatttgc tgtcatcatc tgtatcttgc
     6361 cagtcaatga tagttcctcc tgatgtgtca tcaagcttga tgaccgtttc ctgaggtgcc
     6421 tctattgact gcggacggtt cctcctaata tcaatctgct gcacaatcac atcaaaatcc
     6481 aagtcgtcaa ggccctcaaa cggatcgtcc tttatctcct ttaccttatc attgttttcc
     6541 acatagttgt gggcaaagac taccttatcg cttagccaga caccgtactg aatgcctgct
     6601 gcttttttgc gctggtcaat atctgccttt gatgtaaact tagcagctgc tggatttgta
     6661 atgcgcatgg catggtgact agcgtcaata ccagtatcaa taacagcaat aaccttacct
     6721 tgacccttat agcctctatt ccaagctcct tctgttttta tccagcggtg agtatccata
     6781 tttactggag gtagctcgcg cgattcttct tgctgcttga ctgattggtt agattccgtt
     6841 agcgcttcca tttcggaaga aactaatcca gtcgccattg cctcctctgt cttttcctct
     6901 gctttacttg actggctgtc gatgtcctga gcattaacag cagctccctc actagcctga
     6961 gagacagaca atacctccct tgattcttga tgttgtcctg ctgacacgtg agctgagcta
     7021 actccctgct cctcagccac aactgatccc atccctgtca gaaaaaggat tccgatcaac
     7081 acagaaacca ttcctgattt atatttcctc agtgagaagc gttctttttt ctccacttga
     7141 tgtcctccta gatttattaa aaaaggttat tttaaacaaa tgattcattt atgttttaat
     7201 caataatgtc taagctattt aaccattttt taatcacaaa agcaataaga ctagaagctc
     7261 tcagtttatg tcatttttta atcattcaac tcactgaaat gaggcctctc agaacctgtc
     7321 tcatcaacag ataaggctaa actcagccgc tagacttcaa aaatgtcaca ccatttttag
     7381 acattacctg tcctcatacc tataacagaa ccaagcttcc acagtcgcct tggccttatt
     7441 tttttgttac aatataggtt aagattatca tttagaaagc gaagaaaaat gaaactcatc
     7501 tcatggaaca ttgattcttt aaatgctgcg ctcactggtg aatctcctag agccctctta
     7561 tcacgcgctg tacttgatac tctcgtggca caggacgctg atattattgc aattcaagag
     7621 acaaagctat ctgccaaagg ccctaccaaa aagcaccttg agagcttgct tggctacttt
     7681 cctaatcatc tcaatgtttg gcgttcatct gttgagcccg ccagaaaagg ctatgccgga
     7741 accatgttcc tctataaaaa agagctcaat cccattgtca cattcccaga tatcggagct
     7801 cctaccacta tggacgctga agggcgtatc atcaccctag aatttaacga tttctttgtc
     7861 acacaggtct acaccccaaa tgccggtgat gggcttagac gcttggaaga gcgccagctc
     7921 tgggaccaaa aatatgccga ctacctagcc cagctcgatg cccaaaagcc tgttttggct
     7981 actggtgatt acaacgttgc ccacaaggaa atcgacctgg ctaacccagc tagcaaccac
     8041 cgctctccgg gctttacaga tgaggagcgg cttggcttta cgaacctgct taaccgaggg
     8101 tttacagata cctttcgctt tattcatggc gatattccaa acgtttatag ctggtgggca
     8161 cagcgcagca agaccagtaa attgaacaat accggctgga gaattgatta ctggctcacg
     8221 tcaaatcggt tgattgataa ggttagtcgc tcagagatga tttcctcagg agaacgtcag
     8281 gatcacacac cgattttatt agaaattgat ctatagacta gaagcattcg gacaaatcaa
     8341 cccagacatt aaaaaaaaat ggctctgcaa gagaaccgtt tttttaatcg cttaaagacc
     8401 tagatcctta taggctgttc gataccctac ctgcaagacc tgattatcct gtaagaggat
     8461 cggccgctta atcagcatgc catctgttgc caaaagctcc gctgcctcct caacgctcag
     8521 tgaattaacc ttatctttaa gcccaagctc acgataacgc ataccactgg tattgaaaaa
     8581 gcttttgagg ctataatctg aatgctctag ccattgtttc agctgctcag ctttaggggg
     8641 attggcctta atatcaatga tatcaacctc agaaaccagg gtctttagct cagcaagggc
     8701 tttttgacag gtactacact ttgggtattg gtaaatggta atcattagct actccttatt
     8761 aacactaatt tgctcgtgcc tgagcaacca ggccttcttt tcaagtcctc cagcatagcc
     8821 aatcaagcga ccatcagcag ccagtacacg atgacaggga ataaaaatac ttaaaggatt
     8881 acgtcctatg gcaccaccaa cagcctgagc cgaacgacac tgcaggcgct tggcaagctc
     8941 accatagctc aaggtctctc cccatcttat cgtctgcaat tctcgccaga cagctcgctg
     9001 aaaatcagta ccctgtggag ataagcaatc aagcatggga tagggcttcc tctcaaagta
     9061 agcgtcaagc cacaaacagg ctctttttaa cagggcatgc tgctcctgcc agatgggctg
     9121 cactttaatc ccagcctgaa aatacctttg accttcaaac caggctccta tcaaagcaac
     9181 atcagtcgca accaaggata tttttcctaa gggcgattga tacacacact cgtacaatgg
     9241 caagatctga cctccccaca taatagctta ttcccttgac tatttattat aagaaaaagc
     9301 ctagctaaag gcaagaagga gccctctgac accacaacaa acgcatgaaa aaacaatagc
     9361 ggctctttca atgctgccat acaatcgtta gtgtcaaaag tcgcttacta tacagctgcc
     9421 ccccttgaaa aacgaagctg gaaagacaca acatgctaaa gctgtttcac gcgctggtgc
     9481 ctgattagat gttcttctaa ttaaaggcca atgttctgat taaaaagtca tttcatgcgc
     9541 tgatacctac tcaaataaaa acacatagcg tggggctaga ccaatccctc acaagtcatc
     9601 aatagttcgt ctatgagcta cactttatca cattgggata ggcagacata tttgccggct
     9661 cagttgtact tgcctgatag ctaaccaaaa gcccgataag ctttttccga tcctatatca
     9721 atagctgtag cggctatcct cgctaatctc ctgataagcg gctctttcat ggcttttctt
     9781 aattttttga taggctaagc gctcgccatc aattggtacc ttgccacagt aaacaaagcc
     9841 taacttttca atgatatgcc gcatgacctg attatgctca tgagtatcta tccgaaaatc
     9901 tggtccatgc tgcccctcaa tgagcccttg caaaaaggtc tgagcaattc cctgaccagt
     9961 cctatcactc agcaccgcca cacgatgaaa ggtcacataa cggtggtgat tatgctgcca
    10021 cctgccatca taaatcttgt cgtaggcgtc ctcttggcca tcaataacag ccgcataagc
    10081 aacaatctgc ccctcaagca aagccacata gccctgccct tgcaacacat cagcagcaat
    10141 atcctgataa gcaggatacc catctgcttt ctgccattgg ctggagcctg attgggctaa
    10201 ggcagactta gctgaattga tcactgtcat gatctgacta agctcattag gaaaagcaag
    10261 tctaatctcc atcgttcaca ctcacaatct attctgattt gatgatgcta tgctaccgca
    10321 aaaagcctta caccttgtca ctctgctagg gacacctcat agcggtatgc ctgcttctca
    10381 tctcagctga gtatagcaca atagtcatca tttgacaaaa agcctcttca aggattgcca
    10441 gcaatcatgc tataataaag taaatcacaa aggagaacca ttatgattaa agaattttgt
    10501 gctgaaaacc taaccatgct aaaccaattg accagccagt cggtcaatcg tgttgagctc
    10561 tgcgacaatc ttgcagtcgg tggcaccaca ccctcttatg gtgtcatcaa ggaagcctgc
    10621 gacctcctac atgacaagca gattagtgtc gcaacaatga tccgcccaag aggaggtgat
    10681 tttgtctata acgaccttga attgcgtgct atggaagcag atatcttaaa ggctatcgaa
    10741 gcaggaactg atgccttggt cataggctta ctcactaagg acaaccagct tgacaccgat
    10801 gctatcgaac agctcctacc agctacacaa ggactccctc tggtttttca catggccttt
    10861 gacctgattg ctcgcgacca acaaatcgca agcctagagc agctcattga ctatggcttt
    10921 gtacgaatcc tgcttcatgg ctcaagcgat accagatcca tctatgaaaa cattgaccat
    10981 atcaagcagt tagtcaaggc tgctcagcac cgaatcgaaa tcatgattgg tggaggtgtc
    11041 acagctgata actgccaaga gctaagtcaa ctaacaggaa cagctattgt gcatggcaca
    11101 aaaatcatct aactatcagc tcaaataaag gaaaagtcac tccctacaag gaggtaaata
    11161 atagcagccc ttctcgttga aggccatacc tgagccctta gactaggctc ctagcaaact
    11221 aatagtatag gaccttcgct gcctttacat caaaaaggct gccgtccaga aaaagagaaa
    11281 gccacacatt gatagaaaac catagctggc tctactacta tcagtatcta tcatcagctt
    11341 ctgagctgcc taaaagtttc ggtgatcatt aacaagtaca gactatttgt ttctaaatta
    11401 gatcataaaa cagacaatta taggaagcga caagtgaatc attattcatt ttttattgat
    11461 tactatgata ctataagtaa ggatagcgct ttctttttgt ctttgctttg cctgactatt
    11521 aggctctaga tttatttttt accatactaa tataagaatc ggaataaata atgacaacaa
    11581 ggtattttta taagctattg ctaacgatgt tgacactagc attaggagga ttttccctat
    11641 ctgcttgcca ctccaagatt agtaagccct atcaagtcgc tatttttgac aaggatcatg
    11701 ttaggacctt tatggaaaaa gctgacagtc tggtgcctgt tgagaccatc tctcgaacac
    11761 agcacaagct atttgagcga gaaagcttta agcaggccaa gcaagggtat tttgcaaaga
    11821 caagagaagg aaatgacctc aaggttctgt taactcacat tgatcaagca agcctagaag
    11881 aaaaagtcct tcatgctgat ggcaatgacg cctacacctc tacaactgat ggtgattact
    11941 tttacacaac agctgtcttt gccgatcgta ttgactgcta caagtatgac cgccacttga
    12001 aaaaacaggc tcacaagtct attctaaatc aagacaccat taatgccagc aatcagtttc
    12061 tggtgattga tgacgctctg tacctgcttg tcagcgctgt agacatcaag agtcagcagc
    12121 ccaaaactga gctatggaaa atggacaaat cctttactat cactgatcgg atagatctgg
    12181 acgaaagcac tgcctatctg cgcatggtca acgtcggacg aaccctttac attacccagg
    12241 ctgctgatgg cattttagaa actggagaac ctagacctgg taacaaggtg atgacctatg
    12301 acttagatag cggtcaaaag tcctatctca tgcttcatgt caatagtcct agagccattt
    12361 accaccatgc caaaaccaat gagcttatca tcgaaaatga tcagcattat aatcctgact
    12421 ttgcatggac catctaccag ctagataccg gagaggagag aaccattcgc tttgaggagc
    12481 tagccggtca ggagacaagc tctccctact ttatgatgac ctcaagcaac tactacttcc
    12541 tctttccaaa aaggctttac cgatacgatt gtagtaacca tcagatgacc tgcatcaacc
    12601 tagatcagta cggagtgacg cacgcccatg ccttgatcgc taagcccaca ccataaatca
    12661 caacaggcct aatcaccact cattcatcta caccccaatg cttagacaaa gcagtgtact
    12721 gacccccaaa agttggacac gacatattag tgaaaggatt tagttctgta ttgcacaggg
    12781 ctaagtcctt tcactaatat gtcgtgtcca acttttgggg gtcagtacac tttgggaaag
    12841 tatgtatgaa tctccagaaa aaatacctta tcaactacct ctatatgaca agtatgaggg
    12901 aaataatagt ttatttagag ataatgcctc accaaatttt agggcggatg tcaaagatat
    12961 tacagctact ttagtggctg ttttaagtaa tggttatcca accgggaaaa gcagtttttg
    13021 taaagactac tgtcccgatg aaatcagggc aagacaatta acccaattag ctatttggta
    13081 ttttacagat ggtatttctg aagaaacgtt gaaatcaaat tatagtctaa atgatcttga
    13141 atttcaagga ttaaagtatt taatacaggc tggcaaaact gctgggacta gtaacaatcg
    13201 aactttagat atctatatat ctaaagatag aaattcaaaa tttcaaaatc ttttaggttc
    13261 taccttagta gttaaaactc cagaaaacaa agagaactgt caatgtacta aaatttatat
    13321 agaagaaaat ggaaaagatg gttattatct ttacatctat gaggatacga ataaaaacga
    13381 taaatatgac aaaaacaaag ataaactact acagaaaaaa tacataaaaa atgggaaaga
    13441 cggcaagcct ggcctaaatg gtcaacgtgg gcctcagggc gaacctggga aacaaggacc
    13501 acaaggtcct agaggtgata aaggggaaac cggagaaaaa ggacaagatg gtaaaccggg
    13561 caaacaaggt gatcgtggtc cggctggacc tcaggggcct agaggtgaca aaggggaaac
    13621 tggagaaaaa ggagaccctg gacgtaatgg taaagacggt aaaccaggtg aaaaagggga
    13681 tcctgggcaa caaggcattc ctgggcctaa gggtgatcct ggaaaagatg gagaaaaagg
    13741 tgaacgtggg gagcaaggac ctcgtggaga aaatcccact cctaccccag atccaatgcc
    13801 acaaccaatg cctgaccctg cacctaaacc agaatccaag ccagaaccta agccgatacc
    13861 tcaaccagag gttaagcctc agccagagac aaaacctcaa caaccaaaca agccatcaac
    13921 cattactagc caacctagcg gcaaagcact accaaaaaca aacgacacag gcagcttgat
    13981 aacagtattg ggaacaggct tgctctctct tcttggactg ggcttcttaa ctagacgcaa
    14041 aagaaaacaa taattaaagc actatctata gctttttaat cattggctat caaacaaatc
    14101 acaaaaaagc ttatcgtttt actcctaacg ataagctttt tcgtattctc tattacttgg
    14161 tcccaatact atttttccag ctttaggctg gttttgttaa tccaaaataa tatcagacaa
    14221 tttccgtttt aattaaaaaa aaaaacgaaa ctgcggaagc taattatcag aaaatgattc
    14281 acagcttaga gtcaccatgt taagctattc tacggagaag aaaggtttgg gaatgactat
    14341 ttctaaactc aaaggagaga aacatgagaa aaacaatgaa gaagatgcta gcagcctcga
    14401 cagtctgcat catcatgtcg ggcagcttta tcggaggcgc ggcaagagta ctggcagagc
    14461 agtactatgg ctatgatgat ggaacaaaag acggtggaga ctggccagta tttttatatg
    14521 taacaccaac aaatcacccc gaaagaaaaa ccgataaaga gcactgtgtc tattgcttta
    14581 acaggttaaa tagttcacct gagctctggg aatctcaatt taaagatcca agtaagctag
    14641 gtataaaact ccctatctat gaaaagaaag aaggagatga aagcctttta agagctaaat
    14701 ctcagaagcc cagtgataac ttaacttcaa aattagttac tgttctttca aatggctatc
    14761 ctaataagac attaggtaat ttaagtgaag atcaaagtcg ccgattaaca cagctagcta
    14821 tttggcactt tactgatgga tacgctacaa atcatttcaa agatggttat catctaaaca
    14881 aagatgaaga ttcagaatta aaaaagttaa ttgaaactgc tgaaaaaaac ttccaaacta
    14941 cagcacatac ctatagctta aatctttatg taacttcatc atataattat agtacaggta
    15001 aattttatca acatcttctt ggttccactt taacaccaaa acttccgaac ccaaatccag
    15061 gacctaaacc accaggtggg aacaatccac atcatttacc aggtgaaaat ggtcaaacta
    15121 aatatccaga aggagaaagc ggtgaggcag gagctcctaa aaagcccgag cctaaaccag
    15181 agcctaagcc ggaaccaatg cctaagccag agcctaagcc acaacctgag cctatgccag
    15241 aacctaagcc taaaccggaa cctcagccta aaccagcgcc tcaaccagag gttaagcctc
    15301 aaaaaccaac caagccatca aacactacta gccagtctag cggcaaggga ctaccaagaa
    15361 caaatgaagc aggcagtcta atgacaggac ttggaacagg cttactctct cttctcggat
    15421 taggcttcct aacaagacgc aaaagaaaag actaagacac taaaagatta tctatagtcg
    15481 tttagttgat cagtatctag tctaatacaa cacaaaagcc ttatcgcgcc ataaatggaa
    15541 cgataaggct ttttaagctt ggttcaaaaa gggtaagaca acttagtcta gcgatgtaaa
    15601 ggcttcatca gcacgcttgc tagtaccatt aaggtcatgg ctgctacaaa caaggccaag
    15661 aaataaggcc aagcctcacc tagattaccg ccattttgga aagtgctgat gatggttaac
    15721 acccaatgtt gtgggagtag ctttccaatc gcctgcatat aaggcggcgt aatactaagc
    15781 ggccacaaac aacccgccag catagaggtt ggcatcacaa tcagattagc caattgactg
    15841 ctttgttgcg catttttaga aaccgcacca atcattaagc caaagcctat agctaacaaa
    15901 ctataaagaa agaaagtcaa caaaacaatg gctgttggaa tgtaaaagct gacatttgct
    15961 accctgagta atcccagcat aatcactatt tgtatcgcaa aggcaacaat accaacacag
    16021 acatagctca gcatgtattg aaggcttgat agccttgata agactaagcg attgtagatt
    16081 tgactggact tatcaagcaa gataccaccg tacaagacac tggtgctgcc tagcattagg
    16141 atcaataaaa agccagttgt tgtcgaggaa acagacttac tttgggaacg atcagctagg
    16201 gtgatttctt tgaccttgta ggatagcttc gtgttatgag ctgaaatctt cttgaaaacc
    16261 tcttgattgc ctgctgccgc atcaccaatg atattgtaat tctccaagag ataattagcc
    16321 tgcgccttaa accattctgt tatttgacta tcagcaatcg aacgtagagc gatcttttga
    16381 gtgtctcctt ttagaacctt ctcaccaaag cccggctcaa tggtcagcac agcctccagt
    16441 gtcttggcct ttaggtattg atcaatagcc ttttcctcta gcctagtata tatctgatat
    16501 tttttattgt gctttaattg cgacacaaac tgcttggaaa cctgactctt atccttatct
    16561 aagatcccaa tcttagcttg acttccccct gtaaagctca aggacaaggc cagcattgtt
    16621 gttagcatag gcaacaggat aaaggtgata tagcttgttt ttttacgtct aattttgata
    16681 aataaggctt taataaaagg aatcatgctg ccacctgctt tctcattctg accaaagcaa
    16741 agaggataaa ggctgttcct ataccaagat taaccattaa ggtaaccggt atgggattgg
    16801 actgcccacc aaaaataaga taaaacaaac tatcattgac ccattttatc ggggaaatat
    16861 tagacagctg attaatcaag gcgctattta aggttgacaa aggaatatag cttcctccca
    16921 aaaaggcaaa gacaggaatg actgcattag acgctaccgt caaaaaggat tgatttctaa
    16981 taccagtcgc aagcccgata ccgatggcaa cagacaaata aactagcgag gccgtcacac
    17041 cgataatctg ccagtcatta gtcccccaat taacacgtaa cacaaatcgg gtaaagacat
    17101 aaagaatggt tagctggact gctgttgcta gcataccacc aattaatttt ccaagcaaaa
    17161 tagcactatt tgagacccct gtcaaataaa tgcggctagc caccccttgc tgacgatctg
    17221 atagcaccag attcatcgct gacataatgc tataaaaggt aatcatggta aacatggaaa
    17281 tagcatagta atccgctgag ctcatgcctt tactggtttg cacagagcta gaggcgatat
    17341 agtctatttt tcttttcttg atgttgctaa tggcttctgg ataaaggtta gcaatcgaat
    17401 cataggtctt ggcattatcc acatagatat tgacaagcat attaatcaaa tcagcattct
    17461 gttggttaat gctgttggtg gtcacctcaa tgttttggtc gctcttaacc tctagagctg
    17521 ccgtcaaggc gccctcgctg accttttgct tagccttagc gatatccttg gtttctttag
    17581 cttctaaatg aagctcttta tttaacagct ttaaaaacgt gataaagttc ttttgatact
    17641 ctgtttcctt gccctcaagc tgataacgaa ccgtcaattt aggaacagta gctgctgtat
    17701 taaagctgga cttaaaagca aagcttaaaa tcagaatcat caagatagga aaaaccacca
    17761 tcatcaacaa agcagtccga tccctaaaaa tctgtaagct ttcttttttg attaaatgaa
    17821 ataagatcat aacaacccct aatctcttag cttcttacca gtcaaatgca ggaagatttc
    17881 ttctaaattc aaatgcttat gcctaatctc actaaaagca atatgagcat ctgtcagctg
    17941 acgaacaacc gagccaatgt cttcatgttc aatcaggaga actgcttcaa gctcgttatc
    18001 catcagtctc caattgggct tattagagag atcgattgct tggtcagctg cgactgtcac
    18061 catgatttgc tttgtgaaat cagactcata gcgtctttct agctcggcct gactgccctc
    18121 ttcaatcacc tgaccatgat ccataatgta aatgtaatca cataaggcct caacctcttc
    18181 catgtagtgg gtcgtgtaaa taacagtagc tccttgctca tttaacaagc gaatagactc
    18241 taaaatatga ttacgagact gtgggtcaat ccctaccgtc ggctcatcaa agatgattag
    18301 cttaggagaa tgcaccaaag cacaggcaat gtttaaccgt cttttcatac ctcctgaaaa
    18361 ctggcttgga aactggcttg cctgtgattt taaccctacg aactccaagc tttttaaaac
    18421 ctgctccttg agctcacttc cctttaagcc atagagagag ccgaaaagct caacattctc
    18481 ataggctgtt aaatcaggat aaacagcaat atcctgaggg acatagccaa tcttggaact
    18541 aatttttcga atagatttat aagattgctg taaaacagtc acttcgccag cattcaaagg
    18601 gattaaccct aaaatagcat tgattaaggt tgacttacca gcgccattag gccctaaaag
    18661 gccgtagatt ctcccttcct caattgtcag tgagacatga tctattgcct ttttgccgcc
    18721 tcgatagacc ttgacaacat cttttaactc tacaaaactc atatattatt ccttctttcc
    18781 aactctaacg ctgctcttta aaactaatta acagataagt taaggtcaat aaaagcgaac
    18841 caatcaacca accatataat aaggctgctg tcacacacca gacaccaatc acactaaaga
    18901 ggcatagggc tagtagctgc tgtagccagc ctgagtaacg acaggccttg accaaggcat
    18961 agcccaaaac cacaagcgta agacctgcca ctgaatcttt tcctaaaaag agacatagac
    19021 ctaagtaaca aaaagcatca accagtgtga caagacttaa caaaagaaag ctagctgctg
    19081 ccctatctgg tttaaaggct agccaagtca tttttcctaa gagcaggcga ctgtcctttt
    19141 tcagcataag atcaaaaagc aagaccaaaa ccaacagggt cagctctacc aaggctatgc
    19201 tatacaatag cacataacaa atgatttccc agccaaagga tacgcgaccc aaaaaggtca
    19261 gcaaaccatc aagagctaaa gcatcagaaa ataatagaca aacaagcact agaccaagct
    19321 ggattagacc aagcaataga tcaagccatt gctgatagga cattgccctg atgtgcctta
    19381 aatgccatct gactaagcgc cgtcttttat gacttgttag aaaaagggtc actaggatta
    19441 aaaaggatag caatgctagt attatgatca tcgtaccacc ttcttatgca ttgattgaag
    19501 atgactcaag ccttcaaccc ataaattgcc tccaacatga acaagcaaca ccagccataa
    19561 gctctgacta acataataaa tacttccgta aataagacca gtcagtattt tggcgtaaaa
    19621 aatggatctg cccatcagga aatggtttag ggcatagcac aggctggtga tcaacaagac
    19681 aagagcaatt ggcaatcgcc attgaagcca caagatgtta aaccaaatca aacgataggt
    19741 gatttcctca cagcaggcca aaaccaaggg atagcctatc tgtggccatt tttgtgtcgt
    19801 tccgacaaat gataggacta agggaagcca ctcttttttt tgccagcagc ggctaagatg
    19861 taaaaaagca acctcaacaa agagcacaac aaagctcaag ataaaaccaa tgatcaaaag
    19921 acgaccatca ctatgaccta agggcgcttt aataggaggt gacagcaggt aaatccctgt
    19981 taagactagg gcataataaa ccagtacagc tcttaaaaaa cctattagat taaagctata
    20041 gctatcacga ccctggccaa aaatagcctg cattgcgatc gaaggacaaa aggtagccat
    20101 taaaaagcat aggttaaggc attgggtgta caaaggcatt tgtcacacct ccaaactgtc
    20161 tcatgcgtgg atgattagca aatggaaagg caggaatgca catctcaaga agctcaggag
    20221 tgaggacacg tgtcacgtac cagccttttt ctgaggcctc aggaggagta atgtctaaaa
    20281 agacagcatt aggacttact tttttagtgt aggctagtag tgtctttaaa tcctcttttt
    20341 tatctttccc agcatggttt gtcaggtcac taagacgaac ctctcctgaa atcaagggct
    20401 caaaggcctt ccatttaagc tcctgatcct ttggatgagc atagtaaaag acgttactat
    20461 ctaggtctaa aaacaaggga gagtcactct cagcattttg tgttgacgtt ggattataaa
    20521 acaaattata gtaatagcta tagctaatag ctgaagcttc catgattcct cttaacaggg
    20581 tatgcttagg atccaagccc gcctgaaccc caaataagag ataaggacct tcattggact
    20641 tgtttttaag gataatacca aaggtataaa gcggattatc ttctccaaca gtcatgtcaa
    20701 tagggataat ctcataaaga ctgtccttac caagtctagc ctcttccaaa agagctagaa
    20761 tttccggatc atcaataatc actctgggac aaggcttttt agtatgccag ctaagcatca
    20821 tagagtcgat ttgaatatac tcaatcaagc tattacacat ggctgcttcc agcgttgtat
    20881 gagaggctgt ccccgttgaa aagcctggaa tgatgtgctt ttcgcctaca gcctgattgg
    20941 tcttatagcc aacgcaaagc atttgggcag gcacatacat ctccttatct tcaaaaaaca
    21001 tcggacactt aacccagccc aagacatcgt cttgcgtcac cattttatca cacatgatca
    21061 tgtgcaaatc atggcaacgg tcaatttgtt cctgcgtaaa aacctgcaaa tactctaagg
    21121 gcatgacagg atccgtctgg ctcaattcct tataagaagc ataaacaatc cggtctgata
    21181 ataattcccc agcaataaca gtggcataac gctcaatgct ttcacctaag tatttgatca
    21241 aggcttcctc ataatgactg ccataaccaa tgatatgata gctcacctga ctcagctcac
    21301 caataaattg cttgtggtag tcaggcatct gtcctgtcac actctttaag taaacatcat
    21361 gaggatggtt acaaatagga acctgagatt gatttaagat accagttcgg ttaccactaa
    21421 ggccctttag cttatcaaga atatggttga acgaagggta ataatgtagc atccttagac
    21481 ctccttatga ctcttcttga aggagttttt taacaatctc acgtgttgaa atctgttgat
    21541 cctcatacct taattttgtc agagcccctt gtgtctgaga attagacatt ttcaaaatat
    21601 cctgcacctg aatctcaagc gttggcaaat agacacttaa caaacgccct tcaaattttg
    21661 agcttcctgt ttgagcaata ataaaggcct cactgacaac cagattcatt aacacattta
    21721 acaaaggtac ataagaggag ctaacaggct gtgttggcgg caactgctga cttgcaaagc
    21781 gctgataaag cgtgtgatcc tgtaaacgtg ccagcaccct tctctccaag ctatcaaaat
    21841 cagcactatg aggaggattt aaggtacaag catggataaa cggcccatca acaaagccaa
    21901 gcaccaattg ttttttcaag gccacactga tttcattaag gtgacgcagc atcataatat
    21961 tcaaccggcc ttgacaaata acaatactct gatagtctgc gagcttctca gataagcact
    22021 tcatgttgcg atggtgctcc agagcatcta agcgagaggt aacatctgtt tcttgaatga
    22081 gcatttttag ctcatcgcta gccacctgaa ggtttaagtt caggtgcttg gccagcagct
    22141 cagcagattc attgacatag cttgaatcac tgataaataa gacaggtgca gtatccttag
    22201 cctgtcctga ttcagctatg aaatgataat tgcctgttaa gaccttcatg atattttctt
    22261 caagagcata agcgtcttca agcatcaata ggtcgttata atacaaggct gtgatgacct
    22321 ctgacaattt tgcaaataag tcagactcta gtgttttttc gtaggtatca gtatcaataa
    22381 ctttcccgtt aaaccaatcg gagatgatac tgtagtaggc ttcttttaag gcttgtggct
    22441 cttgtgcaat gtctaaaaca gcttcattaa aatcccatag gccttttcta aagcaaaacg
    22501 tatcgtcaaa ttgcacaatg cgaacattgc tatttaattg atatttcatt gagactcctt
    22561 atttccaata atcgtcatgt gaatcacatg ctgggtcaag ccatccaagc ctagcttttc
    22621 ttggaggtat tccttattgt accctccaat atcaacactt ccatatacca aagctgttga
    22681 gaccaattga acattttgag caatctctcc agcttcaata aaggcataag cagtagcttg
    22741 atttccatat ttacgtgtgt ttttgatgta ctgataaaca tagataagaa tgacattgca
    22801 gttttcggca gtgatcggtc cgtattcggc aaaggctcta atatcctcct gatcactaag
    22861 atgatgacac ctcagcgcgt gctgataagg aaggtattca taaaaaccgt ccttgagtgt
    22921 ttctacgttt cttgcataga aaaataaggt gatggggtac agacccccac cagaagcaca
    22981 atttcttaag gctactgtct tagtcatgcc ttctttgatg attgcctgag agctgacacc
    23041 acaagcataa taaagcaaat cagccaaatc ctgcaaaggc atctcctcat ctataaactg
    23101 cctatgactt ctccggttgg tgatacaggt tgatagggct gctgagacct tcttagcttt
    23161 aggaagtgct atcgtgtttg ccctatcctc aaaatagtca ctatttgaaa aggtggtcac
    23221 tgcagaatcc gtaaaaaact cagccacact ggtcttaaac cctaggtaat tgttattagc
    23281 cttgtaattc atcaaaaacc gttggctaag attgtctgtt tcatcaggca tcaaatgctg
    23341 tgccacaagc tgttttgatg tttttaatac cgtttgatga tgataggttg ataacgataa
    23401 gtgattggta ttaaattcaa ataactgtcg tgcttcttct cttgttaggt cactttggtt
    23461 atccgaacgt tgtttttcct tagaaaaaaa tggcataact gtcttcctgt aatatattaa
    23521 taaataatag taattagcag gtaccgacta gtacctgcta attactacaa gacgttgaca
    23581 tcaagctgat tgtcttcgtc tcttgtcatg taacacccct atccaacacc agctaacacc
    23641 atcaattaca aactgtaacc ttagtcgcta gcaaactaat gattgtgacc tagctattaa
    23701 ctattaaata gaagtattaa agtttacgct tttggctcag ctgcaccata attgttgttt
    23761 atggtagtat tgccccatga agctgagacg cagcaacaac aagaacagca acagcagcaa
    23821 ccaccaggag caacttgagt tgtttctgct acactagtag ctaaaatatt tgaagcaaat
    23881 tgtaacataa tgcttacctc cttatatcgc ctgatcggta aaacaaaaca ctgataagag
    23941 ttaaatgaga atacctctca actgatagca aaagcaatca tgagcaggta tccagcaaca
    24001 caaggctagc tattttgtat cgcccttgtt aaagtgacca ttcaattctt accaactata
    24061 ttatattaaa attcaagaca tatgtaaata ctttctttaa tattttctta caaaaatgtc
    24121 attatttttc cagaaaggtt agcttattga gcttgacaaa gtcttaagcc tatctcttta
    24181 atggcattta taaactatca gtctttttaa tgaaacgcat taaaataggt agagatatta
    24241 ttatctctac ctaaactgta ttgatgagac agatggctag tacctcacaa ttaaccattt
    24301 ctaaaaataa tgactctttt gtcgaaagac ctaatgatta aagctatttg tctttgttta
    24361 tctttttctc attagtaaca ttaaatcatg gcaaaatatt tatattcatt taataatcaa
    24421 gattccggat catcaagtga ccgtccatgc agaccttttt cgcgctgcac ctgtcttaat
    24481 ttctcaggag taacatcgtt tccgtcttca tcaacaatct taatgccttc aatgtgatgg
    24541 cgcactgagc ggcgatagcc ctcaatgtat tcctcacgca gcttggcctg ctctaccttt
    24601 tcaggaccag tcaagccaac tgtttttttc ttttttgcaa gctcgttaat acgagcgatt
    24661 tttttaggat ccataaatca catataaggg ctgcaccaaa agcagtgagc agctgatgag
    24721 gcttgatgat gggctagaca gcctctttag gaccgttact aggacctttc aagtcctttt
    24781 tcaccagctg tgccagcaag ggctgcctgc aaatggggct gcctctaatc ctttctcttt
    24841 cgtttgtgac atagagtact gcactctttt tgtctatatc taaggctgtg ccagcagctg
    24901 cttagcctta tgcttctgcc aagaaggctg tagcaagctt cttgtgaaaa gctaaaatcc
    24961 atgctcactt tactaacagt gttcctgatg cttttattga ccactgacca gcacagctat
    25021 tgctagcaaa gctagcccaa gacgatatct cgtagtaagc aagaggactg atttgactaa
    25081 gtatcaattg cttgataagt cttgagtgct tagggaagga cttatcccaa ggcaggtaat
    25141 cagtcaccta tatcatctag ggaatacgaa cagctaacac agggcgatgt gcttaatctt
    25201 acacagcgaa ttatttagta tttaatcggt caaaggccgc aatggtctct acctttttaa
    25261 ccagctctgc taacagcgct aaacggttac gtctaatagc ttcgtcctct gtcatgacca
    25321 tcgtatggtc aaaaaagtca tcaataactg gactaagggc aaagacctga gctagctgtt
    25381 ctttggctga tccagatagc actagtgaat caacagcctg tgccaaagcc ctttcgtagt
    25441 cattttcaaa gaggctagca tcaatcagca cagcgtcaac tgcctttttc gctagattaa
    25501 agacgcgaga cagcgactcg acagcaggct tgtaggtgtc tagctggctt gccgcagcca
    25561 gagcctccgc tcttgctaac agttctggta caacaaagct tgagctagcc agaactgctt
    25621 cacgtatatc ctttggaatg gctgagccca tcattttatc cacacgtgca caaataaagt
    25681 ccagcacctc agccttatgc tgataggtca agctatcaaa tgacagctca tataggctat
    25741 caatcagctt atccatagga atgctccagc cgaaatgctc aagaattcgg acgatcccct
    25801 gagttgcacg acgtagggca taagggtcat ttgagcctga cggtatcaaa ccaacagaga
    25861 aaaaggacag cagggtgtct agcttatcag caagagcaag gacagcacca acctttgttt
    25921 caggcagctc tccttctgcc gaatttggca aataatgctc acgaattgct gttgcgacag
    25981 cagcagcttc gccagttaaa agggcgtatt tctcccccat aatgccctgc aactcatcaa
    26041 attccccaac cataccagtt agaaggtcaa atttataaat ctgggcagca cgagcgacag
    26101 cacttttttc tgcttctgag agcccagcct ggtcagcaag aaaggctgca ataaccttgg
    26161 tccgctccat atgctcagcc acagagccta tcttttcatg gaaggtcaca tgagctagct
    26221 tagcaaccaa atcttcaata gataactttt gatcctcacg ccagaaaaat tctccatctt
    26281 caagacgagc aacaagcacc ttttcattgc ccttaatcac attttgaaga tgcttagcat
    26341 taccgttacg aacagaaata aaattcggca ttagcttgcc agcctgatca cgcacgacaa
    26401 aataacgctg atggttcttc attgaggtta ctagaacctc ttctgggatt tccaggtact
    26461 tgggatcaaa acttcccatg aaggcagttg ggtattctac taggttgagc acctcattta
    26521 agaggtcctc atcaatatcc acctgaacct tttgctctgc ttcgatggct ctgatttgtg
    26581 ctatgatcat ctcttgacgc tccttagcag aggcaatgac aaattggctg cgcaggtcag
    26641 cctcatagga atcagcactt gtaatgctag tctcttctcc aaggaagcga tgtccgcgac
    26701 tgatacgtcc cgaatgaatg tctaaaaagt caagctccaa aggctcatca tctaacagta
    26761 caatcaagct atgcaccgga cgaatatagt caaagctatt gttagcccag tgcatgctga
    26821 ctgggaaggt caaggaagca agaacctctg gcaccgctgc taagacgtcc ttagcctgct
    26881 tgcccgcttc atgcttggtg acataaacgt attcctcacc tttgacctct cggaattcga
    26941 tgtcatcaac agtcaagccc tttccacgaa caaagccctg agcggctttt gaaaattgac
    27001 catctgcgtc aagagcaatt tttttagagg gtcccttaaa atcctctgtc agatcagtct
    27061 gctgatcagc taagcccagc acacgcactg ctaaacgacg gggcgttgaa aagccttcga
    27121 ttgcgtcata gctaagccga ttggccttaa gaaaatcagc catacgttca acaagctgct
    27181 tttcactagg tgtgacaacg taggcaggaa gctcttcaag accaagttct acaagtaaat
    27241 cttttgtcat cattaaaatc ctatgggcat caaatctaaa agagaagacc aaaccgatcc
    27301 tagcatgcct tgggcaagct tggacgatcc tttgtctaca agatttgtcc catctttctt
    27361 tcctttcttc aagttatggg gtaggtttag gagaccaaat cactagctcc taatcctgca
    27421 agcctgctaa taagctgcct gttagacaag atcacttagc agaaagactg agcttaacag
    27481 gactagtcat caggccttta agtctcatcg cttttaaaaa gcacctacca gataggtaag
    27541 ctgctagcag caactagagc ttacaagatc atacaagctg cattgactac aaggaactag
    27601 tttagatcca gctgcttagt cctctgccag caaggctact cggctagcat catccaacaa
    27661 tgggaagcca agctttttac gctctgcaac aaaggtttta gcaacgctac gagctaaatg
    27721 acgaatccga gcaatatagc cagcacgctc tgtcacagag actgcaccac gagcgtcaag
    27781 caggttaaag gtatgagagc atttcaagac atagtcatag gctgggtgga caagcccttg
    27841 tgctaaagca cgctctgctt ctttttcaaa tatctcaaag ttttcaagca gcatgtcctg
    27901 attggatacc tcaaaggaat acttggaatg ctcatattct ggctgaagaa aaatctcgcc
    27961 gtacttaaca ccaggtgccc attcgatatc atagaccgaa tccacctctt gaatgtatga
    28021 ggccaagcgc tctaagccat aggtgacctc tgctgtcact ggtgatgttg ctaggcctcc
    28081 cacctgctgg aagtaggtaa attgtgtaat ctccatacca tcaagccaga cctcccagcc
    28141 aagtccagct gagccggttg aaggattttc ccagttgtcc tcaacaaatc gaatatcatg
    28201 ctccaatgga tcaatgccaa gtctttcaag agattgcagg taaagctcct gaatattact
    28261 tggagaaggc ttcatcacca cttgaaattg atggtgctga tacagacgat tgggattttc
    28321 gccgtatcgg ccgtcagcag gacgacgaga tggctccaca taggcagcat tccaaggctc
    28381 tggaccaata gcgcgaagga aggtataagg actcatggtt cccgctcctt tttcattgtc
    28441 ataggcttgc attagcatac aaccttgatc attccaatat tgctgtagcg tcaaaataat
    28501 ctcttgaaag gtaagtttgt tactcatgat ttcctctttc tattttttat gtcttgtcgc
    28561 aggcgctaac caagagctgg ctatggcttg actgctggtt ggctcttaaa cagcttttca
    28621 aagagaaaaa ccgcgcctat agccacctac acctaaaggc ataggggcgt caaaacgcgg
    28681 ttccacccta atttattact tcatttgatc ttgttgataa acagatgtca agcaagctac
    28741 aaacacctga gcctactctt tagagaaagc gccaaccagc agtaccatca ctcggctctc
    28801 accagccccg agctcgcttt agatcagaaa cctgctattt tctttcctat tggttagttt
    28861 atcacaaaat cctatgattg tctaatcaac tattatgatt ttggacgagt tccgtttgga
    28921 ataataacct cagacaagag cctattttct tcacgaatgc gcagataaat cacaataata
    28981 tagcaaggga aaagcagcat tgccgtaatc tgagcatggc aaagcaaagc aataccaacc
    29041 agctctggag caatgtttaa aaagtaattg gggtgcttaa cagtcttaaa gagccaatga
    29101 tcgacatatt tatggtcctt tgccagcatc agcttcactg tccaaatatc tcccaagatc
    29161 cgagttacct catatagcac agctatcgaa aaaatcatca gcagcaagcc aagaaagcta
    29221 atgccatcaa acttaatctg cttgagcaat gcctctgtca cagcaaagac ataaatcatg
    29281 atatgcagca gggtcaaaaa cttagtgttt tgcgcaccaa attccttgcc cccattagcc
    29341 aggatagcct tctcgttttt gatcgatttt tttaagaata ctaaacgaat agcaaacatc
    29401 aagagcatca ataacaggat aatcaaagta agactccttt attctagttt aatctgtttc
    29461 tttcacgaaa cactaattaa gattatagct aagttacaca gccttgtcaa accgttttca
    29521 aaaaaaagat gtctttcttt gatctctaaa aacaagaggt cgtcacacag caccatcaag
    29581 agacctcatc aaagctttaa ggtcgtacca aatcaccatc aaaagacagc tcctagactc
    29641 agtcaattca cgagcagcaa gcagcaccca agaggcattt tgcaggcctg acctacttcg
    29701 cctgtcgtaa acacaaatcc tcaatatggt aaatagcgtc acattgcgct gcaacctcat
    29761 cgctgtgtgt tgccattaag acaatcatat cctcagtctg acaagctctg atggcttgta
    29821 agacctcctg ctcagcctca atatccaggg cgcctgttgg ctcatctgcc aataacagct
    29881 gcggtgtttt gaccaaagca cgagcaagga ccactaatgt agctcactta atccctgcag
    29941 ctcttgctaa aagtccttgg tatcaggatc tgggatagct gacatacccg gcaggcaacg
    30001 aatgcgctct gaatcctctg gactaatctc acaatcaaaa atagccatat tttctactat
    30061 gcgttccttg tgcaccgact taggtagagg aataaagccc tcagcaatag accaagcaag
    30121 ggctagctga gccactgtct tgttgtactt tttagccaat gcctgcatgg tatcatcggc
    30181 aaatatctct ccttgtccta atggacccca ggcctctagc aaaatgtgat gcctgcggca
    30241 ataatcaacc gtctcttttt gatagcagcc aggcgccaag cgaatctgat tgactgctgg
    30301 tgtaatggtt gctgtctgtt taagagcctc cagatggtga accataaagt tgctgacacc
    30361 aatcgagcga accaagcctg cttcaacagc ctcctccata taagaccaag ctgctgcatt
    30421 ggctgcttgc cagcaatccc taagagcctt aggatttggc caatgaatca gataaaggtc
    30481 tacatactct agtccaaggc gctcaagaga ggctgctaag gctgccttag cgccatcata
    30541 gctatgagca tcattccaga gcttagtggt aataaagagt tcttcacgag gaacgcccga
    30601 atcccgaatg gcctgtccaa cacttttttc attgtgataa atggcagctg tgtcaatatg
    30661 acgatagcct gccttaatcg ctgctagggt ggattggtag gcctcctcac catcagcagc
    30721 cttaaaggtc ccaaagccaa gcactggaat agcaagacca ttagccattg ttactgtttt
    30781 aatcatatct aaaacctcct ttttcattgt agcacaatga taagcaaagc aaaaagaatt
    30841 gagctgatca ccagcccaat tcctttgctg tattaagcct caaaggcctt ttgaccattt
    30901 aggtaggttg ctactaattc taagtcctta tcaagaacaa taaagtcagc agcatgacct
    30961 gccttgattt ggccacagac atcttcaata ccaaccgaag cagctgggac gtaagaggac
    31021 atgtgaattg cttctgctgg acttgcaatt ccccaggcaa caacattttt aatgccgtcc
    31081 tttaatttta agatagagcc tgctagatta ccactatcct tcaagcgagc tgtgccattt
    31141 tccacaataa ccggaaactc tccaagcatg taatcaccat ctggtgaacc gcctgcacgc
    31201 atacagtccg taatcaaagc cacatgctca tgaccctttt gctgcatcaa aatatcgcaa
    31261 gcaacaggtg agacatgatg accatcgcag atcagctctg caaccgttcc aggaatatta
    31321 taaacagccc caaccatacc aggctcacga tgagtcaagc cacgcatccc attgtaggca
    31381 tgaacccaaa cactagctcc tgctgctact gcctttttag cctcagtata ggtaccattt
    31441 gagtgaccta aagctactgt gacaccctgc ttggtcacct cagagacaaa tgcttctacg
    31501 ccatcacgct caggagccaa agctattttt ttgatcaagc ccttagctgc tttttgccaa
    31561 gctgcaaatt cgtctaagcg aggatttttc atatatatcg ggttttgggc tcccttgtat
    31621 tcctcagtga agtaaggccc ttcaaaataa atcccctgaa tctttgctcc tttgacctga
    31681 tcggcaacag aagcaacggt tgcagacacc tgctctagat gctcaaaggt tgacgttagg
    31741 gtagtcggta agaaggaggt cactcctgtt gataagagac cctcactgat ggcatggaga
    31801 ccttctgctg aattatccat cacatcagca ccagcatagc catgaatatg agtatctaca
    31861 agtcctggtg ctatttgata gcctgtataa tcaataacct ctgcctgatc atcaacagta
    31921 gccgtccaat aaccaaatgt gccattattt agctccaaat agcctgctgg ctttacctcg
    31981 ttggggtaat aaaagcaatc tgctttaata tagcttgtca tcttttttcc tccctttttc
    32041 gtttattata cgccttaatt cttattttgt aaatggtata taccagtcct tctgttaaaa
    32101 agaaaaacct gaatactatt tcaagttttc ccttttatta gagctgtcct gaaagtactt
    32161 tctcagctag atttagggcg tggtcagtga tacgtgtgta atgagatata atgtcaataa
    32221 aattaatccc tgcctgtgct gtgcattcgc cacgattgag gcgttcgatg tgtgttttac
    32281 gcaattgacg ctctttttgc tcaatcgtcc tatgacgctc aacaatagac tgggctagag
    32341 ccttgtcact atccacaatc gccctaatcg catctaaagt taaacagtgg gtcaggtgat
    32401 acatttctgt taattcacca cgtgcagctg ctgaaaagcc aatctgcttt gctgtaatcc
    32461 cctcaatgag agtcgctaac gactcagagt ggtcaccaat tcgctccaaa tcacgagacg
    32521 aatccaacag acctgctaaa acctcatttt cactaggact aagggcttca ttggaaatat
    32581 caacgaggta agtggtgagc tcctcatcaa tcgtattgac cgccttctca tatcgcctca
    32641 ccttttcgcc aaacttgtct tctgctgtca taatgtagct ataagacgcc tcaaaagcct
    32701 gaatagcata ggaagccaga tgtaccaatt ccttgtgggc atttcccaag gcaatagaag
    32761 gagcctgagt gattagtaaa cggtccaaat acaaggcttc atatttgacg atttcgtctt
    32821 cacctggaat taaggtggtc acaagctttg ccagagtgtt gataaaagga agcagcaaca
    32881 gggtatttgt gatgttaaag gtcccatgtg aaaaggcaat ggtcatctca ggtgacaggg
    32941 ccaaaacaga ctgaagccat agcataaagg aggtaaatgg catcagtaaa atcataaaga
    33001 tgaccgtccc aataacatta aaaagaatat gagcagcagc aacacgctta gctgcaatat
    33061 tagagccaat agctgccaaa accgctgtga tacaggtacc aatgttagag ccaagcaaaa
    33121 taggaatcgc accctgcagg gtcaataggc cacccgaaaa aagcccctgt aaaataccaa
    33181 taatggccgc cgaggattga atcagcatgg tcaatgctgt cccgataaaa acaccctgaa
    33241 agggcttgtc tccaagcgtc gctaggtaat gctgaaaggc tgagactgat tttaaaggat
    33301 ccatcgcatc acccatgagg ttgagagaaa agaaaattcc tcctacacca aaaatgatac
    33361 gacctaggtt attgagtttt ttatttgacg tgaaaaagag acaggctgct ccaataaaaa
    33421 tcatgggcag ggcgtaatct cccagcttaa aaccaatcaa aaaggaggtc actgttgttc
    33481 caatgttggc ccccatgaca ataccaatcg cctgctgtag ggttaaaagg cctgcagata
    33541 ctaggccaac tgtaatcacc gtcacacccg agctagactg aatcaaagca gacatagcta
    33601 ttccaaccaa gataccaaag aaggggttgc ttgtgtactt gtcaatgtaa tacctaagct
    33661 tatcacctgc ggcctgctgc aagtcgtctc ccatgtattt gatactgaaa agaaaaagac
    33721 ctaagccctg tactgccccc caaaaaatga aacgcaatgt cttgccaatt taccgacaca
    33781 atattgtcct cactcgctta tttattctct tctattttaa tgtatttatt cagttatcac
    33841 aagggttttt taatcctttt aaatagtgct catttagaac ctattttaga gccctagtcc
    33901 tcttttcatt ttcctatatt cagggtataa tagtgctact caagcgacaa tgatttcaaa
    33961 ggagatacca tgagaaaacc gacaaaagag acccactacc tcatcattag cttgcttact
    34021 attgccattg caggaggggc ctaccttatt tttagtagcc tctctccaaa gccagctacc
    34081 attaccaccc aatctaaggg ctatgagctg ttaactaagg ctcaagcatt agtcaaggag
    34141 gccgaagaca acccaactaa agaagctatc gcaaaggctc aaaaagcaat taatcagcta
    34201 aaaaagaccc agtctaagga ggaattacag gctcgactaa cagctatcag cttaaagcac
    34261 aatcaagaag acgttgctat caaggtccta aaggcagccg aggacaatcc aagccctgaa
    34321 cttaaggagg ctgcacaaaa agccattagt aagctctctg atgaggctaa aaaagctgcc
    34381 ttacaggcta gacttgacgc tattggactt tcaaagccta gcactgcaca gcctgagact
    34441 gcaacaccag cagcagaaaa aaatatagca ccagctcctg cggctccaca aataaagcat
    34501 accacaccgt cttctggggg aacgacgcca gcaccgaacc ctaaacctag tcctaagccg
    34561 aatcctcagc ctagtcctag tccagctcca gagaacccag agccaacgcc tagtcctaac
    34621 cctcagccaa atcctcaacc agaaaccaac acacctagcc ctcagccacc tgcaacagag
    34681 caaagtgaaa acactgctcc agcaggacaa aactaagaaa gggcagccag agctgctgta
    34741 gcttagttac acttcttagt acaggcaata agggcttagc tactgaaata atgctaaact
    34801 tacgactaat aagctctctg ataaaaagag gctttaggtg attaaaaaca gctggttcta
    34861 aaaggattcc agctgttttt gtgcttctta attgattttg aggtaggaag agaagggagg
    34921 cttaatcaag tcgataagta atcccatatc ctctcctaac tctctatcag cttggctatg
    34981 attatagagc ggctcaccct tacgcgcttt ggtgattcgt catggatatt ctgactggct
    35041 tgaccatttg agttttttcc tcagtgtcac tccctaagac ttttaaggga ctgacgaggt
    35101 gattagcatg cacaacaaaa agcccttaaa cacaccttta aggaccttgt attcagctta
    35161 atgcctctat agtatcaggg atatttgtta aggcagctct cagctaaaga cttgtgataa
    35221 agacctatgc ctatccgacc actagctaga gtcaagctgt gcatagctca gcctctatga
    35281 ctaacagaaa ccagaggcag cgttagatca ctttgcttag cttaaacctc atagcccatg
    35341 agaagccctt cagcttctgc atagaagctg cataggcctg aggctgggct ggtttgaatc
    35401 tctgcttctg ggtaaatcgc tctaattttt tccgcaattt gctcacagat cttagggttt
    35461 ttggcgtggg agataaagac tcggcctcct ttatagcctg ccttttgaat ctcttctaaa
    35521 acagctgaca ctgccttttt ttgacctctg gccttttgaa gcagctcaag cgtgccttcc
    35581 ttacttgcct gtcctaccat tctgatgttt aataagccaa tcaccttacc aatgagctta
    35641 ttcagacggc catttttaac cagattatca accttggcca acacaaaaac aagcctggtt
    35701 ttttcctgat aagctgtaat tttctcaaca acctcatcaa aagaaagccc ctgattgatc
    35761 aaccgctcta gctctaacac aatcaaatcc atctcaccac ctgctgacaa agagtcaatc
    35821 acatggatat tggcattcgg attttcctca agcaagtcat tttgagccaa tctagcacta
    35881 ttgtgactgc ctgagagcgt accggtaatg gtaatggcaa tgacgttatc tgctcccctg
    35941 taggcttgta aaaaagcatc aggacttggg cagcttgagg ttgctggctt agaggactga
    36001 tacatagtct ccatcatttg atcaatatct agaccatcat catctctaaa aatatctgaa
    36061 ccaatctgta gggttagcgg cacacgctca aagcgcaggt gattggattg gctttttagg
    36121 gctctaatat cgcagcctga atccgataca attttccagg tcattcgttt tcctcttttc
    36181 cttcatagtc tgttttggtt gacaaagtaa gcattttccc ataaaattat atcatcacta
    36241 gctagacttt tgctagctaa acgacatcag atgtaacact tgaaaggtat ttgtaatggc
    36301 tggtaaacca atttctaaac agtcccttca aaatttagcc cactgcaatc aggaatccag
    36361 acggttaaca cgagaagcta ttgaaattgc tctgcttagc ttactagaaa agaagccctt
    36421 aggacacatt accatttcag aattggtagc tagagctggg gtttcaagaa atgcttttta
    36481 ccgcaattac agctcaaagg aggatattct tgagtgtctg ttgacttctg ttatcagacg
    36541 tatctttcgt ggactgaagg cctttgatct aaagacacag gcctatcagg catggcttta
    36601 tctgtttaca gaggccaaaa aagaagcgac gctacttagt attatcttta accatcacct
    36661 gcagcagctc ttgacgcaga tggttaccaa gcgtttgaga gcctaccaaa agtggcagga
    36721 aaaaaagctg tctcactacg cactgctctt ttggagcaac gctattgtct cagtcctttc
    36781 caattggatt tctgatgata tggttgttcc tgctgaggag atggctgcta tggggctgcc
    36841 cttattagcc tagttgtctc tagatcacct atagctccta gacaacttcc caagaaacca
    36901 agcttgcagc atcagacagg acgcttggct ggcttgactt aagcactggc actgcctacc
    36961 aagatatgta ctagccctac tacaggcaag gtgtgacttg tcgctcgctg ttgtgcagag
    37021 gcttaaaggc tcttacattt agctggacaa taaaaaaaga ctgaagaggc tggctggatt
    37081 agcctgctct tcaatccaga acctcctttg ttggaggttt tttcgtgttt tatttttcag
    37141 tcgatctcac acacctaggc ttgtggtgtt ccaagacagc tcagctctag tcaacacctc
    37201 taaaactgag cttatcatct ctagcttttg gaggcctttt ctgacgggct ggtttgactg
    37261 tgcttaagag ccctttgtca atgcaaattg attaatggca tgggccacgc ctgcttgatc
    37321 attggagagg cttaccttgt cagcgacctt tttaattgcc tcatcagcgt ttcccatagc
    37381 gacacctaag ccagcatagg ctaacatttc aagatcattt gctgcatctc caattgccat
    37441 cacttggtct gggcgcagct tcagatcagc ggttaattcc ttcagggcag aggccttggt
    37501 cacacactcc ggcattacct ctaggattgt ttcttgactg cgaaccacac taaagcttgc
    37561 gctgagtttt tctctaacaa gagcctcaaa agtatctagg gcagcctttt ctcccatgta
    37621 catggcctga aatatgattt gactgctgtt ggataactga gataggttag tagcctttac
    37681 ctttgtaaaa accaaatcac catcagcctg aaccatatct ggaaccttgc tatctatcac
    37741 aagataatca cgctctccag tcagggtgag gtaaatatct gaaaagggct gagacagctg
    37801 ataaaggtgc tcaatagctg aaaaggtcag gctttgataa tgtagcagct cccagcttgg
    37861 gctcctatag gtgctacagc cattgtttaa aataaggtac tcctccttat cactcaagcc
    37921 taattgctca aaatacggcc ttgtcccaga ctgggggcgg cctgtgcaga gaacaacttt
    37981 tatcccctct tgtgcagctg cttggatagc cttaatattc tcttttggaa tgtgcttttt
    38041 gctatcaagc agagtaccgt ctaaatcaat tgctataagc tgaatcatcg tctcagtcct
    38101 ctttccattt tatcttaggt aggtgccatt gtcttttgtt gccaatcata cgcatgactg
    38161 tcaataaaac aaccagcaag tagcattcaa catttgaagt ggccagctta aaataaagca
    38221 caagtgctgc tataatagac cagccagcat aaatctcact tctaagaaca gttggcttac
    38281 ggcctgccag gacatctctg accacacctc cgcctgcccc tgtaagaacc gctgctacaa
    38341 taacagcgct taagggctgg gctagtcgaa cagcatgtag agccccctga acactaaagg
    38401 ctgcaagtcc gatagcatca gtcagcaccg ctgctctcac ccagccctta gccacaagct
    38461 taggaaatag catgatcaga ataatagcta taaaagcgca ggcaaattct ggtctttgtc
    38521 cccacaaggc ttcaataggc agcccgatca gggtatttct aatagcccca ccaccaaagg
    38581 ctgtgacaaa gcctagaata aaaatcccca gaacatcaaa ctcctcctcc atagcgacaa
    38641 tagcgccgga caaggcaaag gctatcgttc caataatgct taaaagctcc cacatatcaa
    38701 ttgtcataac tcacctaatg cttcctaatc ccctattagt ctaccatctt tttaatcaaa
    38761 atataagtca aaataagagc aaggtcctca aaaatcctac tgatgacctg tttttgtttg
    38821 caccaaagat ttagccccta tataggctag gctcctagta gcaggagtta ggagcgatag
    38881 cttgccaaat tcacagcctt gttattttcc atgagaaagg gctctgctga tgtcttggtt
    38941 tgataggtct tgtatttatg gtagaggtat tggtagcaat cctgtttttg atcaaagagg
    39001 atggcttggt agggctcttg gaaggacaat ttctcaacaa acagatactt gctcttatac
    39061 tccactagca ctcccacatg accaataaaa aggtaatcac catctagctg atcgtgaatc
    39121 acaacagcaa gcattttggc tgggccatta aagctaacag ctgagaaatg ctcttgcata
    39181 tgcttggcat gcacctgaat atccttggtg gcttccgttt tcactcttga aaacagctgc
    39241 ttaaagcgct ctgtctctgc ctgtgtaaag agctggcttg tggtaatggc gtcctcgtcc
    39301 ataaataaaa gcgtatcatc actgctggta ggcgcaatcg tcatgctatc ctttagaagc
    39361 ataaaggtgt tgatccggca attagttcca atgaaattgc cttgcttttg cgaccacaac
    39421 tcatcgattg ctaccacatc atagtcaggc tgcttctgat aggtaaaggc ccctgtcaag
    39481 cctgttttgc caactaggct attatattct tgtacaccag ccataaaggc attgacatta
    39541 gcttccttca gctgatgtga tagggcagcc ctgacctcct gctggctctt tgcactgttc
    39601 atgttggata ggaaaagacg tcccttctta gcctgtggct ctttttgctc ctgcttgggc
    39661 tgatcagact ggtgagaagc ctggcaagcc ccaagagttg ccgtagcaag gattagcaaa
    39721 gacatcatta cttttttcat cataacctcc tttttaatga gtcattcaag ctggtactct
    39781 ccatcatcac caaatgagat tatcagcagc tggcagctaa tacgaggttg ctacaaccca
    39841 cttgttatct ctttatgtca tgacctcatc gttaccagta tagcataaaa aagaaaagca
    39901 ccagctcttg aagccttgca gcccttgtgc cggtgctttt cgttaggaga ttacactgaa
    39961 atagtttttg tggtagctag ctgctgatac caataagcgc tttttttagg gtaacgcttt
    40021 tgggtttcaa aatcaacata gaagaggcca taacgcttat catagccatt tgaccaagaa
    40081 aagacgtcca tcaaggacca gataaaatag cccttaacat tagccccagc accgatagcg
    40141 tctgcaatca cagccaaatg ctgcttgatg taatcaattc tagcgtcatc atcaatcctg
    40201 ccatcaatac aggtatcctt gtagccaagg tcattttcag tgatataaat ctttttatag
    40261 cctggatagt ctgccttgat ccgcatgatt tgatcgtaaa gcccctgtgg atagatcatc
    40321 caatcccagt ctgtacgcgg cacatcaaca tcaaacacgc gttgaccaac cccctttatc
    40381 tgatatttgg agccgccttt ttctcccttg ccattatgaa tgatttcggt ctcaccatgg
    40441 ctaataataa gccagacttc tcatcacgta ccttagtggc tggcaggcca tattcagggt
    40501 ctagcaggat agaggaggca tagggggtta gctcctctga taccagagcc tttagggctt
    40561 cgatttgcca aggagctggc tctgtgtctt ggtgggctgc catcatgcgc tttaaagccc
    40621 cgcgttgatc aaaggccaag gccgaaatga ttcccttacg actgaccttt tctaaataag
    40681 cttttttgtt tcttgttaat gtcatcttat acctcctcta cttgaatacg gtcaaatagc
    40741 tcatcaaaat gtgccatgtt aacatgacct gttcttgttt cttgcgcatt taacatgcct
    40801 aaaacattgg cttttttcag aagcgtctca tcgtcatctc cttctgccaa agcccaagca
    40861 atccctgcca cagtagcgtc accagatcca acaggattga ctacctcaat tttaggaatg
    40921 gtaacacggt aaaacctgtt atgatgtttg gcaaaggccc cttgggcacc aagagaaaca
    40981 ataatccatt ctatcccttc aaataaaggt tgactcaaca gagagattaa acgttcctca
    41041 tctaatgtga caggttggcc tatcaaatcc tccaattctt ccaaattggg tttgataaca
    41101 gttggtttat ctttgccagc cagtaccgct tttaaaggag caccagagca atctaaaacc
    41161 actttgctgc catagactct cgccatagta atcaagtctt gataatagtg agcggccaga
    41221 cccttaggca gactgcctga aaaggttaag acatcaaact gcttagcaat aatactcatg
    41281 tggttcaaaa agccttcggc ctcgtccata tcaatgtagg gaccagcttc cagaatttcc
    41341 gtctgcatgc cttcatgtaa aacagcaata caatttctcg tttccccttt gattttgaag
    41401 aattggttag aaatgccctg ttcttgtaac tgatgaatga caaagtcacc cagtttccca
    41461 ccaataaatc ctgttgccac aactgactga ccagcttctg ctaacactct ggtcacattc
    41521 agccccttac caccggctgt ttttgtcgtt ctgtcaacac gattaaccgt gtccaaagtc
    41581 agacgattta gaggatagga aatatcaatg gatgggttta aggttaccgt taaaatcatc
    41641 gcttctccct aatcgtggta gtcaccgcga tcccatttgt ccaaaaactc tgtaaagaag
    41701 tcaggatctt cttggttagc attatgactt tccaaatggg ctatcttagc aattaacttc
    41761 ttattctctt cggtttcctt atagtctgcc tttataaagg cctcaataat atcacacatc
    41821 aaaagctcac ctgtgatttt accaccaaag ccaatcacat tggcattcaa ttcttctttg
    41881 gcataaagcg ctgttgtcat atccctaaca agcgctgagc gaatgccagg aaccttgttg
    41941 acagcattag tgatcccaac accagtgcca cagatacaga caccaagatc agctaggcca
    42001 ttggcgacag cctcaccaac ccttttccca aaaatcgggt aatgggtgcg ggtatggtca
    42061 taggtcccac agtcaatcac ttcatagccc tttgatttca aaaaatctga aacagccatt
    42121 ttttcatcag tcacaatatg atcacagcca atagcaattt tcatgatatc ctcccttcgt
    42181 taagccattt tattgagcat gtcaacacga atttgatgac ggccaccatc atagtgacca
    42241 gtcacaaaac ctttagcaat attcttagcc aattcttgac ccacaatttc tgctcccatg
    42301 gtaatcatgc gggcattgtt atgaccgcga gtcatgtagg cagagcgttc atctgacact
    42361 tccgcagcga ccataccttt gattttggta gcgaccataa atggccctgc tccataagca
    42421 tcaatcataa tgcctagact ttcctcatca gccttgagcg ccctagcaac tgctagagta
    42481 ttgtcaacaa agtcatcagc aatcgccgtc acatctgtca catcaaagcc ttcctgctgc
    42541 aaaaagcctt taatagcctc ttttagatca tttccatgtg catctgcacc taagataata
    42601 gtcataggat ctccttttat tgtcattacc gttcaaaatt gtttattttt gttttgtttt
    42661 ttattatttt gttgtttatt gaaaaaagag actgtttatg ctattatgag ttaacaatac
    42721 accagagaaa gtagcggcct atgcttaagc gtgaaagatt gttaacaatt atggaaaagg
    42781 taaacgccaa cggctttatc actgtcactg atattatgga aagcctaagg gtttcagata
    42841 tgacagccag gcgaaattta gatgagctag caagggctgg aaaattagta cgtattcgtg
    42901 gcggtgccca gagcatttct atgcctcaaa agctggagcg ttcaaacact gaaaagctaa
    42961 ccgtacaaat tgaagctaaa aaagagattg ccagatacgc tagtcagctc attaatgatg
    43021 gtgagaccat ttttataggc cctgggacaa cactagaatg cttggctgag gctctaatca
    43081 accgtcacat ccgtattatt accaacagtc tgcctgtttt tacgattctt aataaaagta
    43141 aaactgttga tctcattctt atcggtggtg agtaccgagc catcacagga gcctttgttg
    43201 gcagccttgc aagccagacc atcttatcct tgaagtttgc caaggccttc atcagctgca
    43261 acggtattta taaaaatgac attgccacct acagtgaaaa cgaaggggtt attcagcgcc
    43321 tagcctgtga caatgccatc gaaaaatacc tgctcgctga caaccaaaag tttaacgcct
    43381 atgactttta cagcttttat caccttgaca atatcgacgc cattatcact gactccaaga
    43441 ttagtgacag cgttaaggag cgttaccgcc aatttgccaa gctcttaatc gcaaggccag
    43501 ctgacaatca ggtcagcagc tagacagcct gcctctctat ctgtttccac cctgagtcca
    43561 gcaggtaaac aaagctatca aacgaaatag catcataaaa gcgcatgaag ccactaatat
    43621 tgcaatgggg cttcatgcct tttttaacct atcacacgtt aagcaaagca aaaagaggct
    43681 aggacaaaaa tccttcctct tttaaaatcg tcaaactata gagttgattg gagggctctt
    43741 agccctcatt tttcaagcga tgtggccttt ttaatcagct gctcgagggt ggataaccta
    43801 atcaacatcg ccaggtcatg acgattgaat ggttattcca ctctttttct acgctgaggg
    43861 ctgtgaaagg gctcatacga cagcttagcc gctttctaac agctatttac ctacctcacc
    43921 tcttaacgag cagacagcct aaatggtata gtccagctga tcaagactct ttttatggtc
    43981 aaggtcaata tcaagaaagg tcatctgctt gatattgata aggctggcta caattgatac
    44041 cggaaaagca accaccgctt gattgaagag actaatatta ctattgacaa tgcgttttgc
    44101 tgctgccaag gctgcatttt ccttagcaat ctcattttgc aggctcaaaa actgctcaga
    44161 ggagcgcatt tccggataag cctctcctac agcaaaaacc tcattcaagg cctgctcctg
    44221 tgtcctcatc acatcatttg tttcctccaa ggaaagcccc tgacgcagct tcacgagttc
    44281 agtaaagacc ttttcctcat gcttggcata ggacttagcg atttttagca tttccgaaat
    44341 ggtatcatat ctcttctcaa gagcaatatc gacatttcgt ttagactcct ctataacgat
    44401 tcgatacctt tctaatttgt ttctcactcc aataagccat agtatagtca tgcaaagaat
    44461 aagtgttaac atagatgacg tcactgacat aaaaaagcct ccttaaagct gatgatttag
    44521 tgtatccaac aagcggtaca tcttaacaag cttgtcttga atgttttcat attcgctact
    44581 taacgatagc ttttcaatag cccctctaga gctaggggtt ttcaagagct gttgaccgga
    44641 atagaaggac acaacaacag tatcaccatt catataaact gctacaggca tctcctctct
    44701 ccattcatca agcactgcca gcatataagg atttaagagc attctagcgc ttaattcatc
    44761 tgtgcagtac acattgtacg tttcattaaa gcgaatgtcc tccatttcca gctgcacctc
    44821 accctttagc ttagccttgt agccactatg gaccttttct ctgcccaaaa agcccttttg
    44881 agtcggcaca attctaatat aacccttgat agctgtatga tatttagcca gcagcacctg
    44941 tccgttaaaa tcagtgaccc gatgccagtt atcatcctca ttttcctcat ggtaggcata
    45001 aagattgcaa aattctgtct gcatgtcatc tccaaaaata atatggcaat tactgtcata
    45061 ccatctggag gacggtgttg caagctttag taaggagagc tcaatccctg aatagtaatc
    45121 tatcttgaca tctggcaggg cctcttgtaa aacaggcagc aaaaagtgat ccacatagga
    45181 gagctcattt gctgttttga atgttttcag ccgcggccaa accaagcccc ccacaaagat
    45241 aatgagaaat aaggcaagag atcggtcaac catgccatac aagatgattg cgcctatcac
    45301 cattgccagc cagcccagat tattctttct agcatttcca ctcatctcgc ttttaatttg
    45361 ctccagcttt tggtgatgct caggcgaagc ttctatagct ctactcttct ccaaaacaat
    45421 aggatctgtc aatcgcttag tattttcgtt catctcactt actccagata cttctccatc
    45481 agcagcgctc agctgctctt gataacacca gtcactttat gcttttgctt aacctataaa
    45541 tgacaattgc gttacagcta atttataata ttataccatt tttaaactat tttttctatt
    45601 attatattta aatgacgctc aataataacc acataatgtt aatatagaca tcattgtgct
    45661 cttttttacc taatcatgtt gtgagcaata cccccgttta tcagcggaaa ccataaaggc
    45721 ctctatgaga tcaagactat cagcgccagc ccttcttttg gagtcactat tcagcttgtt
    45781 cttcgcatgc tgtctttgcc tgaccatgat tcagctgctc tttttgattg cttgttatgc
    45841 tcactttttc cgtctcatgc tgagcaagaa aaaacagcaa acccttgctt ggtttactgc
    45901 tcttctgttg atgttagtca aaaaataagc cgggagctaa tgacacccta ttaactcata
    45961 aagcctgtta tcctttcttt gtcatagaac aattcactta gtctattctc aaccaaaata
    46021 cgaagcctgc ttaaaccgtc ttctcatatt aacagctaaa aagtggtgtc aatatgaaga
    46081 aacctatgat cggtaacaat aatagcacct ttaaatctct cagcgataat gtaaggttat
    46141 cctatacctg tcatattttt cggtgctatt tgccatatca ggttgctata gcacttggtg
    46201 gcttctggta gccttaacca ataaatgatc tgctttttta ttcctgctct ttgttttgtt
    46261 tatgcctttt gtcggcgcag gcctttagct ttactatact gacggtaagg tcggtgagag
    46321 cctttaccat tttttatgcc ttaatcgcaa agcatttaac accactgata ttgagctaag
    46381 gctcatcgca aagccagcca gcattgggct taatagaggg ccgccaaaga catgaaggat
    46441 acccatagca acggggatca ttaggctatt atagctaaac gcccaaaata aattttgctt
    46501 aaccactctg atggtttgac gactgagctc taggcattcc accacatcac gcactgctga
    46561 ggtcatcagg ataacatctg ccgcctcaat cgcaatatcc gtacctgagc ctattgagat
    46621 tccaatatcc gctagggtca aggccggtgc gtcgttgatt ccatcaccaa ccatagcaac
    46681 cagctgtccg ctagccttca aatccgcgat aatctgggcc ttttgagcag gcagcacctg
    46741 actaaagacc tgatcaattc ccacctcatt agcaatcgct tgagctgtga gggcattatc
    46801 tcctgttagc ataaccgttt gaagacctaa atcctgcaag gcccttatag ctgccttact
    46861 gtcagccttt agcctatcag caatcagcaa taaagcacat agctgattat ccttggcata
    46921 atacactacg gtttgcccct ttaaggcagc ttgctcggca taggtctgag cagcgcttat
    46981 cgcaatcccc tgctgtgaca tcagctcact attgccaaca gctaagcgat gctggtcaat
    47041 cacaccagtg acacccaagc ccacaagcga ttgaaaatca gtcacagcca gcaagtcata
    47101 gcccttttcc tgtgctactc taacaagcgc ttctccaaga gggtgctgcg aatactgctc
    47161 taaggaagcc acctcctgaa gtccctgctt ctcactagca gcaaggggga tgatccgctg
    47221 tagctgagcc tgaccctctg tcagcgttcc tgttttatca aaaacaattg tccgcacctg
    47281 ataagccttc tctaaaatat ctcctccctt aaaaaggatc ccctgctcag ctgcacgacc
    47341 tgagccaacc ataatcgcgg tgggagttgc tagacccaga gcacagggac aagcaataat
    47401 caaaacagct atagctattg tcagggcaaa atcaaagctc tctctcataa caaagagcca
    47461 aaaaagaaag ctcagcaggg ataaacttaa tacgataggg acaaagactc ctgataccct
    47521 atcagcaagt gcagcaatcg gagccttggc ttgctgtgct tgctccacca gctcaataat
    47581 ctgtgaaagc aaggtgtcat tgccaagcct agagggcttt acccttagcg ctccttggcc
    47641 attgattgtg ccagcaaaca cactatcacc tgtcacctta tcaactggta ggctttctcc
    47701 tgttagcatg gactcatcaa ccgtagactg cccctctact atcagcccat caacagccac
    47761 ccgttcaccc ggttgaataa agcaaatatc ctcattagtc acctgctcta agggaataag
    47821 ctgaagtgct ccctcacgaa taaccctgac atcagttacc cttaaggaca ttagcttctg
    47881 aatagcctgc gaggcccgtc ccttggtacg cccctccaaa tagctgccaa gggtaatcaa
    47941 ggtcagaata accacaacag attcaaaata aagctggtga gcaaattgag cagctccagc
    48001 tacaatctta aaacagctat atgagctgta aataaaagca aagctagtgg ctaaggtcac
    48061 aagcgaatcc atattaggcc gcttctttat caatgcctta aagccatttt catagtactg
    48121 ccgattcaag aaaagaacag gcagggtcag caaaagctga acaagaccat agcttatagc
    48181 atgcgactga ggtgctagag cgaccggcag caccaatcca agcataggtc ccattgcaag
    48241 gtatagcagc ggcagactaa agagagcaga ccacagaaag cgataccatt cattgctagc
    48301 ctgctcctct aggcgctcta gttgccctct catattggtc tcatcaagca gctctgctct
    48361 gtagcctgcc tttcttactg cttgaatgag ctctgctgag ctgaggctgt cagttgagta
    48421 gctcactgat agcttctcag tcgtcacatc aacagctgcc ccctcaacac ctggcagttg
    48481 cttaacagcc tgttcaatcg ctagagcaca ggaggtgcag tgcattccct ctaatagata
    48541 ggtctcttta acaatcatat cctctccttt ttctgacaat gacattgtcc tggcacacaa
    48601 tcacacctta catgggatac tgctccgact tttttagcct ctaagagcaa ctgaaaagcc
    48661 tgaatatctt ccagggtcat tggggtatcc tttagtaatg ccagcaacaa gcggctatgg
    48721 tggcgttgac acatgccatc aagcctctct cgtagcatag caagctgtcg cctgtcctga
    48781 tcaagcaagg actggtaaat ataggaccgt ccctgtctat cagcccttag ggcttttttc
    48841 ttaaccaagc gtccaatcaa ggtcttaacg gtagaatcag accaatggtg cttttcatga
    48901 agaatagcaa taatctcaga gctcttcatg ctcccattag cccaaacaac acgcataacc
    48961 tcccattctg catcagatat cgtatccata ttgctacctc tctttcatct acggttttat
    49021 taagtatagc ttatttgttt acgtttgtaa acaaataata actaaaaaag gtctctttat
    49081 gagaaacagc gtcaaaaaag gactgacagc taaagtcagc agctagcttt taatagtctg
    49141 aactttccag tcttatctga ttaactttat attgacaaaa tgagtccttg tatattacta
    49201 tatgacagta atactgtaat gattaaggag aaaacattga cgtatcttaa aagacagcta
    49261 attctactag cccttctact cacagctata ggtagccaaa caatcgttca ggccagcacg
    49321 cgatcctgga aaagctggtt tattgagcaa tatttttggc ttaaacgaga caaaagctat
    49381 tatgccgagc aggatgagaa taccttctac aactacgtca agtcagctgg tgaaaagagc
    49441 aatcaaggct ttaatctcac tcaaaatgag gtcaacggaa cattaaagac agagtataga
    49501 gacaacatgc aggttcacag ctggaatgaa aactctacta atccatcaaa tcaaaaggtc
    49561 attctctatc tgcatggtgg ctcctaccta aacaacccga cctcatacca tattgacatg
    49621 ctcaaaacct tgtcaactag ccttgatgct aagattgtat tgccgattta cccaaaggct
    49681 ccgacctata cctatgatgt cgctatgcca agattagtta gtctttatca ggatattcta
    49741 aaaagcacta ataacaatgc taacaatatc accatcatgg gagactcagc cggaggcggt
    49801 ctggcactag gtttggcact agcattgaaa aatgaagata ttaagcagcc taaggacatt
    49861 atcctgctct caccttggct tgatgtcacc ctatcaaatc cagagatccc aaattacgaa
    49921 gcctctgatc ctatcttatc ggcttgggga ctgcgcatag taggtgatat ctgggcacga
    49981 cgcggggaaa ataacactaa gcacccttat gttagcccta tctatggaga tacaagcaac
    50041 ctagcaccta tcaccatgtt tgtaggaact catgaaatct tctacccaga cattacaaaa
    50101 tttgatggta tgttaaaaca aaaaggacat aagcaccagc tatttgtcgg ggaaaagatg
    50161 aaccatgttt atcctattta cccgattgaa gaggccaaga cagcacaata ccaaatcatt
    50221 gataccataa aaaaagagta cgaaccccaa aaataataat acaaaaatgc ctaccagact
    50281 tgagtttttt gccaaagcct ggtaggcatt ttctgatcac agcatgacta ctgtttcttt
    50341 tctagctcac ggagcaattg atcaatttta ttaccatagg cgatagaatt gtccttttca
    50401 aaaaccaaat ccggaatttt atacatggtt aattgcttac caagctcacg cttaatggtt
    50461 cctgttgctt tttttaagcc tatttcagcc ttttgattgt ctgaagctag gtcactcata
    50521 atggtatagt aaaccttagc aactgacaaa tcgcccagca tttgcacttc tgtgatcgta
    50581 acaccctgca cacgtggatc acgaaccttt ttgtgtaaaa tctcgttgac ctcacgcttg
    50641 atttccatac caacacgatc aatacgatga tttgtcatgg cccttccttt ctattgtcaa
    50701 atagtacagg ctctcagtag ctcaataaca agagaaaagc ttgatgactt tcaagccttt
    50761 ttctctatta ggctgatggc tatactatta atagtgactg ttcaaatcaa gtggtgacat
    50821 tgtctattgt cttgagacga ggctatttaa gctactagcc accacgatta tttacgggta
    50881 atttcttcca tgacgtaagc ctcaatggta tcatcgacct taatgtcatt aaagccttca
    50941 atcatcaaac caccctcttg ggcattccca atctccttaa catcgtcctt ataatgctta
    51001 agactggcta gcttaccatc aaagataacc acgctatcac gaatgacacg tacacttgaa
    51061 tcacgcgtta ccttaccatt aacaaccata aagcctccga ttgtcccaac cttagagacc
    51121 ttaaaggttt cacgaataat agcctcacca agcatttttt cttgatactc agggtcaagc
    51181 ttacctttca tggcttcctc aacctcttcg atcaccttat aaataatgct atgcaagcga
    51241 atctcaacat cgtctgtatc agcctgctga cgcgcctgtg gtgttggacg cacattgaag
    51301 cctatgataa cagcgtttga agcctctgcc aaggtcacat ctgactcatt gatcgcaccg
    51361 acagcagagt gaacaacatt tactcgaacg ccctcaacat caattttaag gagtgaggct
    51421 gccaaagctt ccacagagcc ctgcacgtct gccttgatga tcacgttaac ggttttgatt
    51481 tcccctgcct tgagggtatc aaataggtta tcaaggctga cacgctgcgt gttttgacgt
    51541 tgcttgagaa gggcacgctt agcacgctcc tcccctgctg cacgcgctgc tttttcatca
    51601 gcatagaccg caaaatgatc acccgccata ggggtttcat tgagaccagt aatagatacc
    51661 ggtgtggacg gctcagctga tttcacacga cgaccaaggt catttgtcat ggcacgcaca
    51721 cgaccaaagg tgttaccaac aacgattggg tcttgtacgt gtagggttcc ttgttggacc
    51781 agaagtgtcg caaccgcacc cttacctttg tcaagtctag cctcaatgac cgtaccaatc
    51841 gcacgaaccg taggatcagc ctttagctct tcaacctcag ctaccaaaag cactgtttct
    51901 agcagctcat caatgttttt gttaaatttg gcagagattt caacaaactc acactcacca
    51961 ccccaagcag ttgagatgat cccatgctca gccaattctg aaataacacg ctcaggatta
    52021 gcccctggct tgtcaatctt gttgatggca acgataattg gaacaccagc cgccttagaa
    52081 tggttaatag cttcaatggt ttgtggcatt accccgtcat cagcagctac aatcaaaatg
    52141 gtaatatctg tcactgacgc tccacgtgca cgcatgcttg tgaaggcagc atgtcctggt
    52201 gtatccaaga aggtaatctt cttgcctgcc tcctcaatct ggtaagctcc aatatgctgg
    52261 gtgatccctc ctgcttctcc tgttgcaaca cgagaatttc taagggtatc aagcagggtc
    52321 gtcttaccat gatcgacgtg tcccataatg gtaacaaccg gtgcacgctc aacaatattc
    52381 tcaggattaa ggtagctatc atcagtaaag aagcgctcga tatcagcttc atcaacctcc
    52441 accttggcct tagcttcaat gccataatcc accattaaga gctcaatggt atcaccatct
    52501 aaggattggt tttgcgttgc catcacaccc atcataaata atttcttgac aatctcagcc
    52561 ggctcacgct tgatccgttt tgcaatttca gcaacggtca ttccttctga atattcaaat
    52621 tcttttggta attcatggaa tttacgctct gttactggtt ttggagctgt gttgctattc
    52681 ttatgatgct tacctttttt gtttttcttg ttgttattcc agttactatt cttttgattt
    52741 ctcacttggt tttgactatt ccaactcttc ttatttttct tttgtccatc ttctaggcca
    52801 tgatcccgat catgcccttt gtctggacga ttttgttttt tacgacgctt atcaaccggt
    52861 tttgctaccg atgcagcagc catactagca accgactcag tagccttagc tgaggcttca
    52921 cgatgctttt tgtcctctgt ctgagccttg agggcggctg ccttagcctc ttgccttgcc
    52981 tgttgctcta agcgtttagc ctcctcttgc tcacgaaagc gtgattccct ttgtctggca
    53041 tactctgcgt tttgctcagc ctttaaggca gcagcacgcg ccttaaaatc aatcttagga
    53101 gcaccggctt gggtctgccc ttgacgtcct gtatcctgtt gacgactatt agcgttaaag
    53161 gaacggtttt tgtcacgatt accagcttgt ctatgcccat cgtttcggtt atttccagat
    53221 gatggcctgt tatcaaagcg tctatctctt tgctgatttt gtgacttgtg gccagctcgc
    53281 tccgtctgct gaccttgtga tcgtccaagt tgacgatagt ctgacttgcg gtcattagag
    53341 cgattttgcc cagcctgccg tctcgctacc tgctccttgg cacgtgcttc acgctctgcc
    53401 ttgaaattgc ggctctttgg cttaacagca accggctgtg atgcttcttg tgtcgcagca
    53461 gctggctttt ctgctgcttt agaggctgct ggctgtggtg tagtggcctt agctgctttt
    53521 gctttttgtt ctgctacttg cttgtctttt gctgaacctg cttgaacatt cttagtcaca
    53581 cctgctgaaa agctagaggc aattttgtta gcatctgctt cttcgacgct tgacgcatgg
    53641 cttttgacat ctaatcctaa ggatttagca cgctcaacga cttctttact acttttgcca
    53701 atttccttgg caatttcatg taatcttttc tttgacaatt tgtgtcctcc tattcgtcta
    53761 tttcataaga gtcctcattt tctttgaaaa tccagcgtct gcaatggcaa ccaccttacg
    53821 aggcttgcca agtgcagcac ttaattccag tgcactaaac actgtggaga cttctacatt
    53881 gtaataatta cttttatctg ttactttttt agtgatattt gggccagcat cattggctaa
    53941 aaaaacaaga ttgacttcct gatgtcgaat ggctttaatg accaattcct cacctgaaat
    54001 cacttttttg gcccgctgag ccagtccgat caaatgagat aatctattta aactattcaa
    54061 ggcctagctc tcttctttta actttgtgat caacatgtgc aatcacttca tcgtaaaagc
    54121 tctctggcac ctccattgag aagctacgat taaacacctg ttttttcttt gccataagtg
    54181 cttcttggtt atctagcttg atataagcac cacgcccatt ttgcttgccg gttggatcaa
    54241 taaaaatctg cccctcctta tttttgacaa tacgaaggag gtcacgctta tcaatgatct
    54301 caccagaaac aagcgactta cgtaaaggta ttttttttac tttaggcata aaacacctct
    54361 tttcttacac ttcctcgttg gttaagagct cctctgtagc tactgcttca gtcattgctg
    54421 cttctttttc tgcttcaagg cgttcatatt cactggctga tttgatgtca atgcgatagc
    54481 ctgtcaaatg agctgccaaa cgaacgtttt gaccacgacg accaatagca agcgatagct
    54541 tattatcagg caccaccaca gtcgcacgct taagatcgtc atcatcaaag agaaccatat
    54601 caacctcagc aggtgcaatg gcattgtaga taaattcagc agggtcatct acccattgga
    54661 taacgtcaat attttcttct actgggatct caagtcctgt cttagcatca tagcgctttg
    54721 gatggaattt actgataacc tttttgatgt tgctgccgcc acgaccaaca atcgttccaa
    54781 tcgcatcaac attgggattg tggctacgca cagcaacctt agtacggtca ccagcctcac
    54841 gagaaacact cataatctca acggtcccat caaaaacctc tggaatttcc tgttccataa
    54901 tgcgcttgat gaactcaggg tgactacgac taacaaagac gttaaccccc tttggattgt
    54961 tttccacctt gtagacatag acatcaatcc gatcatgtga tttgaaggtt tctcctggga
    55021 tttgatcctg atgtgagagc tgagcctcta aggaaccaag gttaacataa atgaaacgtt
    55081 ggtcaaaacg ctcaaccgta cccgtcatga tttcaccttc atgctgcttg tactcattga
    55141 aggtgatttc tcgcatctga cgacgcatcc tttccataat ggtttgcttt gcagattgag
    55201 cagccacacg tccaaactcg ctgactgatt cttcaaaacg aatcttatct cctaactcat
    55261 aggctgagct aatggcaagg gcatcgttca ggctaatttc cagacggcta tcaaatacct
    55321 cttcaacaac ctcacgaacc gtaaaaacct gaaaatctgc tgttttatca ttaaattcaa
    55381 tgacgcagga ttctgcttga ccataacgac gtttataagc tgatttcagt gattcagtga
    55441 ctgcctcaat gatatctgcc ttatcaatgt gtttttcttc ttccaaaata cggaaggctt
    55501 ctagcatttc tttgctcata atgttgtcta ccttgctctc aaagcttggt aaaaatcctt
    55561 tcttatctta taaattaatc catttagggc ttagccaacc gactaaagca aatcgctcag
    55621 caattgcctt ataatttgac agctaaacga gccttagcca ctgcttggta aggaatctca
    55681 actgttttgt gacgcgtctt atctagataa tcaatggtta gggtatcacc atcaaaagcc
    55741 actaaatctc cttgaaaaac cttcacctta tcaattgccc gatagaggct gacattaata
    55801 tatgagccta cagcagcctt caagctctca gcagtcttta atggacgctc tagcccagga
    55861 ctggaaacct ccagcatata ctgatctggg aaagggtctg gagaaatcgt atctaagagt
    55921 ggactgatta gctctgtaag ctcagcagta tcctcaacgg taatcccaga agccttatca
    55981 actaagatac taaggacata atcattgccc attttgtcgt attcgatgtc gaccaattca
    56041 tagggtgctt taattacagg ttctacgatt tgggtaacaa tatcaataat agctgtgttt
    56101 gcgatgttaa taacctcctt tactgatgac tgctatacct ctatagcctt gtcctcttga
    56161 taatcaacac aaaagtggcg agatatttct caccaccctt ctgtattgct ttaacctatt
    56221 ataccacaat caaaatgaat tgcaagaaaa tccctactaa aagtgtcaat aagacctcaa
    56281 aaatcctatt ttttaaaagg agaggagatc tttaaccttg cttttttctc tttccttatc
    56341 ccctctaacc tctgtattca tatgataaaa taaaatatta aagggtaaaa aagacaacta
    56401 aaatattatt tgcggctgct tcatggtctt taccaaaacg aaaaaacctc ccatcagaac
    56461 agatctatgc atatgcgaga gaggccattg gtaactcaat aacatcatta ataaagctta
    56521 aattagttca atttgtaatt ttaataccac tatttatcgg taatataagt ttatctgagg
    56581 atattaaaaa tattaatgct atttttaaag acagcattag
//
LOCUS       DARYYD010000006        51407 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.006, whole genome shotgun sequence.
ACCESSION   DARYYD010000006 DARYYD010000000
VERSION     DARYYD010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51407
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.006"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            33..647
                     /locus_tag="TV188_000287"
                     /pseudo
     CDS             33..647
                     /locus_tag="TV188_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            1177..2055
                     /gene="mvk"
                     /locus_tag="TV188_000288"
     CDS             1177..2055
                     /gene="mvk"
                     /locus_tag="TV188_000288"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEL1533681.1"
                     /translation="MNKTIGYGKAHSKIILMGEHSVVYGYPALALPLKDIEVTCRIFP
                     AAKPLAFDFYDPLSTAVYAALEHLGCLAEPIHYDIMSQVPQKRGMGSSAAVSIAAVRA
                     VFSYFGQPLSDELLEILVNKAEIIAHTNPSGLDAKTCLSDKAIKFIRNVGFDTIDIQL
                     NAYLVIADTGIQGHTREAVNKVAQFEEENLPHLAKLGCFTEAVEQAIKTNDCLAIGRF
                     MTQAHESLKAIGVSVAKADQLVAAALEAGALGAKMTGGGLGGCMIALAERITDAQQIS
                     KKLKEEGAVNTWIQIL"
     gene            2037..2981
                     /gene="mvaD"
                     /locus_tag="TV188_000289"
     CDS             2037..2981
                     /gene="mvaD"
                     /locus_tag="TV188_000289"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEL1533682.1"
                     /translation="MDSNTVTVTSYANIAIVKYWGKKDEAKMIPSTSSISLTLEGMYT
                     TTSLSFLPASAKGDQFYINGVLQDAKEHAKITAILDQFRQKDQTFVKVEASNSMPTAA
                     GLSSSSSGLSALVKACNQLFQAKLSQEELAQKAKFASGSASRSFFGPVAAWDKDTGSI
                     YKVKTDLKLAMIMLVLNDARKPISSREGMKRCSTTSTSFDQWLAQSESDYQAMLRALS
                     DNDFETVGWLTEANALAMHATTKTASPSFSYLTEASYQAMLRVKELRQEGYSCYFTMD
                     AGPNVKVLCLEEDLERLSHLFEREYRIIASKTKELPDV"
     gene            2974..3972
                     /locus_tag="TV188_000290"
     CDS             2974..3972
                     /locus_tag="TV188_000290"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEL1533683.1"
                     /translation="MSKYHVQAGGKLYLTGEYAILRPGQTALICYIPIMLTAVIEAAE
                     AVSISSDMFDHAADLSPDKDYRLIQASIEAFSLYIDKDIKELPAFSLSITGKLERDGK
                     KFGIGSSGSVVVLTLRALAAFYQVQLLPEQLFKLAAYTLLKSGDNGSMGDIACIAYES
                     LVAYTSFDRRKVGQWLIEMTLKELMAAHWGYTIETIEPALPCWFLVGWTQVPSISREM
                     IQLVNKSISCQFLEQSQLVTQEVMTALQLGQRKRLKASIEKAGQLLQGLASVIYHPKL
                     TQLVQACQGLDAAAKSSGSGGGDCGIALVFEAKDIEPILARWQQAGIVLLYQEEWG"
     gene            3975..4967
                     /locus_tag="TV188_000291"
     CDS             3975..4967
                     /locus_tag="TV188_000291"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEL1533684.1"
                     /translation="MTNRKDDHITHALSYHSPYNAFDDMELIHCSLPSYDLADIDLST
                     HFAGCDFEFPFYINAMTGGSKKGQAVNEKLAKVAAATGILMVTGSYSAALKNPEDTSF
                     QLRGVAPDLQLATNIGLDKAVDLGIRAVEEMKPLFLQVHVNAMQELLMPEGERSFKHW
                     KDHLAAYAKQLPVPLILKEVGFGMDIKTITIARDMGVKTFDISGRGGTSFAYIENQRG
                     SNRSYLDDWGQTTVQCLLNAKGLVDEVEILASGGVRHPLDMVKCLVLGARAVGLSRVV
                     LELVETYPVEQIIATINSWKKELKLIMCALDCRTLSDLRQVDYLLYGRLYQANR"
     gene            complement(5252..6535)
                     /locus_tag="TV188_000292"
     CDS             complement(5252..6535)
                     /locus_tag="TV188_000292"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEL1533685.1"
                     /translation="MTKTKPNWAGFYKKSLAERIQQLADDQLLGPQQQKLLETDQLLP
                     IAIANQMTENVIGRLALPFSLAPDFLINGHTYQVPFVTEEPSVVAAASFAAKIIKRSG
                     GFQTEVLSRQMLGQVALYDVKDDEQARLAILANADTLIDVANNAYPSIVKRGGGAKSL
                     TVERKEDFFIVYLSVDTQEAMGANIVNTMMEALVPDLEALSGGQCLMAILSNYATKAL
                     VSAKCQVDLRYLSRHKEEAQQLAKKIELASKLAQIDPYRAATHNKGIFNGIDAVAIAT
                     GNDWRAIEAGAHAYAARTGSYRGLSSWHVDLSKNSLCGELTLPMPIASKGGSIGLNPT
                     VSVAHSLLEQPNAKVLAQITTAVGLAQNFAALKALTSTGIQAGHMKLQAKSLALLAGA
                     SEQEVPQLVKALLKDKPMNLEKAGQLLTAIRLSQS"
     gene            complement(6522..7697)
                     /locus_tag="TV188_000293"
     CDS             complement(6522..7697)
                     /locus_tag="TV188_000293"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEL1533686.1"
                     /translation="MNIGIDKIGFATSQYVLKMEDLALARSTDPAKFHQGLMLDALSI
                     APVTEDIVTLAASAADQILTKDDKASIDMVILATESSIDQSKAASIYVHQLLDIQPFA
                     RSFEIKEACYSATAALDYAKLHVAAHPASKVLVIASDIAKYGIGSAGEPTQGAGSIAM
                     LVTTNPRILQLNHDNVAQTRDVMDFWRPNYSSTPFVNGIYSTKQYLDSLKTTWDKYQE
                     KEGIELSDLAAVCFHIPFPKLALKGLHKIMTKSLADDHKERLYENFQASIAYSKQIGN
                     IYTGSLYLGLLSLLENSQVLRAGDRIGLFSYGSGAVSELFSGQLVDGYKDMLLTNRQA
                     LLDQRQVISVADYEALFYEEPRLDQDGNASFSPYLTGRFALKEIKEHQRIYQDDDKN"
     gene            7882..8721
                     /locus_tag="TV188_000294"
     CDS             7882..8721
                     /locus_tag="TV188_000294"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEL1533687.1"
                     /translation="MTKADHIFKANIKKIMEEGVFSEQARPRYKNGQTANSKYITGAF
                     AEYDLSKGEFPITTLRSIPIKSAIKELFWIYQDQSNSLDVLENKYNVHYWNEWEVGQT
                     RTIGQRYGAIVKKHDIISKILKQLEDNPWNRRNVISLWDYEAFEESEGLLPCAFQVMF
                     DVRRVDGELYLDATLTQRSNDMLVAHHINAMQYVALQLMIAKHFGWKAGKFFYFVNNL
                     HIYDNQFAQAKELLERQPAACQPKLLLHVPDGTDFFDIRPEDFELQDYYPVKPQLTFD
                     LAI"
     gene            8802..9299
                     /locus_tag="TV188_000295"
     CDS             8802..9299
                     /locus_tag="TV188_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEL1533688.1"
                     /translation="MTKKIIAIWAEDEAGLIGACGRLPWYLPKELQHFKETTLNQAIL
                     MGRVTFEGMKGRLLPNRQTLVMTRDSYYHVEGALTITSVQEALDWYHAQDKTLYVIGG
                     SKVLEAFDGYFDVIIKTVVHHQFEGDTYRPRLELSDFVEETSVLYPRDDNNPYDFTVT
                     VLRHR"
     gene            9319..9489
                     /locus_tag="TV188_000296"
     CDS             9319..9489
                     /locus_tag="TV188_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533689.1"
                     /translation="MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGLLFLLNAFTNL
                     VNTIHAFYGTLF"
     gene            9525..10754
                     /gene="clpX"
                     /locus_tag="TV188_000297"
     CDS             9525..10754
                     /gene="clpX"
                     /locus_tag="TV188_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEL1533690.1"
                     /translation="MAGNRSNDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVALSQE
                     IIKEELAEEVLADLTEVPKPKELLEILNQYVIGQERAKRALSVAVYNHYKRISFTESR
                     DDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTV
                     ASVPPQGGRKHPNQEMVQIDTKNILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKID
                     DNASYMQEIIAEDIQKFGLIPEFIGRLPVVAALEQLNTEDLIRILTEPRNALVKQYQA
                     LLSYDGVELEFEKGALEAIAGRAIERKTGARGLRSIIEETMLDIMFEVPSQEEVIKVR
                     ITKEAVEGQSKPILEIA"
     gene            10764..11363
                     /locus_tag="TV188_000298"
     CDS             10764..11363
                     /locus_tag="TV188_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEL1533691.1"
                     /translation="MSEEQILNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSS
                     FINTILGRKSLARTSSKPGKTQLLNFFNVDDKLRLVDVPGYGYAKVSKAERARWGKMI
                     EEYLTTRQNLRAVVSLVDFRHESSQDDIQMYEFLKYYEIPVIIVATKADKVPRGRWNK
                     HESMVKKSLNFDQTDAFIIFSSVERIGIDESWDTILEYL"
     gene            11727..14729
                     /locus_tag="TV188_000299"
     CDS             11727..14729
                     /locus_tag="TV188_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HEL1533692.1"
                     /translation="MTIKKCPQILALFLAFAALASQGQTVHALERQETSVKQAHESDD
                     WFDEDEGVSDIKSNTPTEIDSTVTELFGDAEPKTKAEKEESKAPSPKQEALPAESQKE
                     KETSAKSTDHATVQAEEAQPEQGSDSPWLADDFVTKGDTLVGLSKAGLAKLSKTPVLV
                     LPRIGIDKTVLTRIASFAFTPNKSVAIADYTGRAGEHGEINHLDVEGRDILTEGEDFG
                     AYAIKKLVIPEGYLFIGQDAFNDNKQLEEISLPDSLLSISDYAFAHMSLSKLKLPKSL
                     QSIGDQAFFDNRIAGTLVLPKALKQLGERVFKSNRLTGLVFEGEGLSVLKEAAFQDNA
                     FISLVIPDSIQALEEDVFTGNLGDEEYGNHAVLRTKNGQNPYRLHSANVLVNPSDQAR
                     TPQPPIDYNRWLAEDFTYTGQTITGFSASGLRKVKRNKHLVLPKNYQGQPLTAIADNA
                     FRNVNFHDKTLRKYDLESVTLPSTIQKIGAFAFQSNNLESFEASEDLVEIGQGAFMNN
                     RIEILALNDKLKVIGDAAFHINRIYAIVIPESVEVIGISAFRQNGAKHVMFMGDKLIS
                     IGEMAFLSNTLEEVDLSSLAGLKTIAVQAFADNHLRELKLPDSLMRIEAEAFKINRLQ
                     RVTVPDTVISISFNAFDHNSDDKVVLRTTNHNKNLLADGNGFIVDPDLLSADQSTVQA
                     VLEDLRRLDLASLRADTAAHFMTLITRGKQLLKESAVRLGYQLRFLAESRFFLGRVRL
                     DQLIKTADITLSSHQDTPNAKLLMAKLDKAKLHYNNSAMTAPKVSRLEKELSLLIDLV
                     QGVGAISKATMTQGVYKLQTTLPIPEYYIGVNLYTDDQGNILFVLDMSDTIGQGQLDD
                     YGNPILNVDEDNEGYHALAIESLADYEGLTIKDILTKELNQLPIRDVKQAREHRVGLF
                     MAIRDAAREAQLLLEKQSKALSESAGKSNGSKVADSGLEPSVTLSTNKTKLLPKTGAF
                     KEAWVTMIGMLVLLAATLLKGDSRYKKK"
     gene            complement(14919..17012)
                     /locus_tag="TV188_000300"
     CDS             complement(14919..17012)
                     /locus_tag="TV188_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1533693.1"
                     /translation="MATYYGKDPFENMDDIFNQLMGNIGGYRSENRRYLVNGREMTPE
                     EFQEYRKTGKLAAAEGQEKQASSLKKDGILTKLGTNLTEEARQGRLDPVIGRNDEIQA
                     TAEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
                     GTQYRGSFEENIQNMVKEVKEAGNIILFFDEIHQILGAGSAGSDSGSKGLADILKPAL
                     SRGELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHH
                     NVILPDSVLKAAIDYAIQYIPQRSLPDKAIDLVDMTAAHLAAQHPVTDLKSLEAEITK
                     QKELQEKAVAEEDFEKALTAKTRIEELQKQINHHSEGQKVTATVNDIAESVERLTGVP
                     VSNMGASDLERLKEISNRLKGHVIGQDGAVEAVARAIRRNRAGFDDGNRPIGSFLFVG
                     PTGVGKTELAKQLALDMFGSKDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNQNTL
                     TERVRRSPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNA
                     GFGHQAGDRADQEPAIMERIAPYFRPEFLNRFNGVIEFNHLAKKDLQEIVALMLTEVN
                     QTLAKKGISLEVTDDVKERLIDLGYDHAMGVRPLRRVIEQEIRDRITDYYLDHPTAKH
                     LLASLDQDTITISEK"
     gene            17383..17802
                     /gene="ndk"
                     /locus_tag="TV188_000301"
     CDS             17383..17802
                     /gene="ndk"
                     /locus_tag="TV188_000301"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEL1533694.1"
                     /translation="MEQTFFMVKPDGVKRGLVGEILRRIERRGFTFDRLELRQATPEL
                     LAKHYDTLINKPFYPELEAYMTSGPVLIGIISGNRVVSSWRTMMGVTNPKDALPGTIR
                     GDFAQAPGDDGGIFNVVHGSDSRDSAKREIAIWFGHS"
     gene            18303..19109
                     /locus_tag="TV188_000302"
     CDS             18303..19109
                     /locus_tag="TV188_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1533695.1"
                     /translation="MNKQSMTHFSKKLMKLALLGLALPLSLVSVVDTPVLNQSEKAVY
                     ANDFGSGNRASDYVPAANAWSFEAYPDYYSILGASHLNPAVFPEPSKMSYSPLDELGR
                     TQVARGTITYHNIVMNYNVRQRFAKNQNPSGWIGNPRNVRYTIEWLDGLSYQGDFWNR
                     SHLIADSLGGAALRVNAITGTRTQNVGGRNQRGGMRYIEQKVQQWIEQHTSAVVYYEA
                     VPIYQANELVPRAVVVSALSSDGGLDEKVMVYNTANGYTIDYATGAFRSN"
     gene            complement(19401..20366)
                     /locus_tag="TV188_000303"
     CDS             complement(19401..20366)
                     /locus_tag="TV188_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1533696.1"
                     /translation="MNNRNKRRKKRKIFKMINLMLLLACIIGLSAIVYLYKSHSKISI
                     SQLSQAIPKISLFSKTDKKPAPKPSKKATNKEASHTNSQQQKGAVSWTKQQNPVKLPI
                     LMYHAIHVMAPEEAASANLIVAPDLFESQLKAMKEAGYYFLSPEEAYRVLSANELPAE
                     KVVWLTFDDSMVDFYNVAFPILKKYDIKATNNVITGFTEAGNAANLTLDQMKEMKQAG
                     MSFQDHTVNHPDLSQASAASQTAEMKDSKEYLDRELHQDTIAIAYPAGRYTDTTLKIA
                     EDLHYKLGVTTNEGLASAANGLLSLNRIRILPTTTADILMNTISQ"
     gene            20538..21821
                     /locus_tag="TV188_000304"
     CDS             20538..21821
                     /locus_tag="TV188_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEL1533697.1"
                     /translation="MSVKVALLGFGTVASGIPLLLENNSSKIRAVVGDDLVIAKVLVR
                     DETTKKRLLDQGYSYQFVTSIDDIVDDESIDMVVELMGRIEPAKTFISRALSAGKPVV
                     TANKDLIALYGGELSTLAAKHQVALYYEAAVAGGIPILRALADSFASDKLTRLLGVLN
                     GTTNFMLTKMIDEGWTYERALQKAQELGYAESDPTNDVKGIDAAYKVAILSQFAFGMT
                     IDFEAISYSGIDKVRVEDVTVAQKLGYVIKLVGLLEETASGLNAEVSPVFLPKTHPLA
                     AVDGVMNAVYIESIGVGQAMFYGPGAGQMPTATAVVADMIQTACTLRDHTVSVFNRFA
                     TKTRLAKSEDIMSPYYFAIQATNKFGQLLELTRLCDVCGIRVEQLLSDEIDSDRLDFV
                     MITHEMSKKELACFTALLQDHQDFRMLSTFKILGD"
     gene            21823..22683
                     /locus_tag="TV188_000305"
     CDS             21823..22683
                     /locus_tag="TV188_000305"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEL1533698.1"
                     /translation="MKIRVPATSANLGPGFDSMGIAVSKYLEVDILEERDQWFIEHDL
                     GDIPNDDSNLLIQTALRLAPNIPAHRLKMTSDIPLARGLGSSSSVIVAGIELANQLGH
                     LNLTDDRKLAIATRIEGHPDNVAPAIFGQLVIASQIGKDVDYIIAPFPDLSLVCFIPD
                     YELKTSDSRDVLPKQLSYKQAVAASSVANLAIAALLTGNLKKAGRAIENDQFHEIYRQ
                     RLVREFQPIKRAAAANGAYATYLSGAGPAIMVMCPNKKKMAIYEAIEQLGLIGQLVSL
                     ELDRQGLCLV"
     gene            22848..24107
                     /locus_tag="TV188_000306"
     CDS             22848..24107
                     /locus_tag="TV188_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEL1533699.1"
                     /translation="MNYQETLDWIHGQERFGIKPGVKRMRWVLEQLGNPQDRIRGIHV
                     VGTNGKGSTVNDLQHIFTRAGYEVGTFTSPYIMDFKERICLNGEMISETDLVKAANCI
                     RPLTDRLISETSLGPATVFELITLIMFLYFGESHPVDIAIIEAGLGGLYDSTNVFQAM
                     AVVCPSIGLDHQAILGDTYADIAYQKAGVLKGGEDLIFAIDNKEARQVFLKKAEQLGV
                     PIWEWRRQFNMLQGEGGYQFNSQLGQLSHLVLAMPGQHQVANAGLATMTSLILQDRYP
                     KVTESVIREALASSFWLGRTELLAPNLMIDGAHNNESIAALIDVISSDYQDKQIHILF
                     GAIDTKPVSDMLQSLERLGDVQVTSFHYPNAYPLEAYPDRLTKVADFRAFLDRLEQAA
                     ADDFFLITGSLYFISEVRQYWKKVLSK"
     gene            24107..24730
                     /gene="folE"
                     /locus_tag="TV188_000307"
     CDS             24107..24730
                     /gene="folE"
                     /locus_tag="TV188_000307"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEL1533700.1"
                     /translation="MLSHINSSNKINQLKRGKPLPINQKKAEAAIYQLLEAIGEDPNR
                     EGLRDTPKRVAKMYLEMLSGLEQDAKDEFTAVFTEHHDDLVIVKDISFYSMCEHHLVP
                     FYGKAHIAYLPSDGRVTGLSKLARAVEVTSKRPQLQERLTAQIANALVDALQPKGVFV
                     MVEAEHMCMTMRGVKKPGSKTITTTARGIYKDSRDDRREVMQLIMEG"
     gene            24738..25538
                     /gene="folP"
                     /locus_tag="TV188_000308"
     CDS             24738..25538
                     /gene="folP"
                     /locus_tag="TV188_000308"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEL1533701.1"
                     /translation="MTIGHYSAAGEAAIMGILNVTPDSFSDGGSYTSVNQALAQAEKM
                     LSEGATVIDIGGESTRPGCQFVPAEEEIARVVPIIKAIKKRYDVLISIDTYKTETARA
                     ALEAGADMLNDVWAGLYDGQMLSLAAEYDVPIILMHNQTKEAYADVTKEVCSFLQARA
                     AAALKAGVKKEHIWLDPGFGFAKNVEQNIALLKGLNEVCQLGYPVLFGISRKRVVDAL
                     LGGGTKAKDRDGATAALSAYAINKGCQMVRVHNVGANRDIVSVLSQLR"
     gene            25545..25904
                     /gene="folB"
                     /locus_tag="TV188_000309"
     CDS             25545..25904
                     /gene="folB"
                     /locus_tag="TV188_000309"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HEL1533702.1"
                     /translation="MDKIRLEACRFYGYHGAFKEEQVLGQIFVVDLELSVDLMAASLS
                     DCLEDTVHYGLVFETVRQIVEEKTFTLIERLAGAICQELFAQFLPIKAIKIAIKKENP
                     PIAGHYQAVGIELERKR"
     gene            25901..26407
                     /gene="folK"
                     /locus_tag="TV188_000310"
     CDS             25901..26407
                     /gene="folK"
                     /locus_tag="TV188_000310"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEL1533703.1"
                     /translation="MTLVYLGLGTNMGDRAGYLQAAVNALSKLPETELLRQSSIYQTA
                     AWGKTDQNAFLNMACQLDTRLTSEALLAATQAIEQALGRVRHEKWGPRTIDIDLLLFG
                     DEPYQSETLVIPHPYMTQRAFVLIPLLEIAPDVTLPGSQKSLRSYLDALEQSDVALWS
                     HEYSNKFS"
     gene            26503..27390
                     /gene="murB"
                     /locus_tag="TV188_000311"
     CDS             26503..27390
                     /gene="murB"
                     /locus_tag="TV188_000311"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEL1533704.1"
                     /translation="MIAELEGIDIRENEALKHYTYTQVGGPADFLAFPRNHYELSRIV
                     DYANHNHIPWMVLGNASNLIVRDGGIRGFVIMFDKLNAVRLNGYTLEAEAGANLIETT
                     KVAKFHSLTGFEFACGIPGSIGGAVFMNAGAYGGEIAHIFLSAKVLTPEGKIKKISAR
                     EMAFGYRHSVIQETGDIVISAKFALKPGNHDSICQEMNRLNHLRKLKQPLEFPSCGSV
                     FKRPPGHFAGQLIMDANLKGHRVGGVEVSKKHAGFMINVADGSAKDYEDLIAHVIRTV
                     EQASGVRLEPEVRIIGESL"
     gene            27436..28590
                     /locus_tag="TV188_000312"
     CDS             27436..28590
                     /locus_tag="TV188_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533705.1"
                     /translation="MTKPIITFDNVSKTFEDSGTQVLKNINFELEEGKFYTLLGASGS
                     GKSTILNIMAGLLDATSGDIYLDGERINDLPTNKRDIHTVFQNYALFPHMTVFENVAF
                     ALKLKKVDKQEIARRVKETLKMVQLEGYEKRSIQKLSGGQRQRVAIARAIINQPRLVL
                     LDEPLSALDLKLRTEMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVASFIGESNIINGTMIKDYLVSFNGKEFESVDGGMRPNEPVEV
                     VIRPEDLQITLPEEGKLQVKVDTQLFRGVHYEIIAYDDLGNEWMIHSTRKAIEGEVIG
                     LDFTPEDIHIMRLNETEEEFDARIEEYVEIDEHADGLINAIEEERNEENL"
     gene            28574..29368
                     /locus_tag="TV188_000313"
     CDS             28574..29368
                     /locus_tag="TV188_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533706.1"
                     /translation="MKKTSSLFAVPYFLWIVLFVMAPVALLLYQSFFDIEGRLTLANY
                     ETFFSSWTYLRMGLNSILYAGIVTLVTFLISYPTALLLTRLKHKQLWLMLIILPTWVN
                     LLLKAYAFMGIFGQQGGINSFLTFMGLGPQQILFTDFSFIFVASYIELPFMILPIFNA
                     LDDIDDNIINASKDLGANDYQTFSRVIFPLSLNGVRAGVQSVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLTTENWGMGSTIGVVLIIAMIVIMWLTKEKSK"
     gene            29365..30141
                     /locus_tag="TV188_000314"
     CDS             29365..30141
                     /locus_tag="TV188_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533707.1"
                     /translation="MKKFANLYLACVFILLYIPIFYLIVYSFNKGGDMNGFSGLTLEH
                     YKTMFDDSRLMAILLQTFVLAFTSALLATIIGTFGAIFIHQSKKKYQNAILSANNVLM
                     VSPDVMIGASFLILFTSLKFQLGILSVLMSHIAFSIPIVVLMVLPRLKEMNQDMINAA
                     YDLGANHFQMLKEVMLPYLTPGIIAGYFMAFTYSLDDFAVTFFLTGNGFTTLSVEIYS
                     RARRGISLDINALSTIVFLFSILLVIGYYYISQDKEEKHA"
     gene            30134..31207
                     /locus_tag="TV188_000315"
     CDS             30134..31207
                     /locus_tag="TV188_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEL1533708.1"
                     /translation="MRKLYSFLAGIIGVILLLATLSFILQKKTSSASQSDKLVIYNWG
                     DYIDPALLKKFTKETGIEVQYETFDSNEAMYTKIKQGGTTYDIAVPSDYTIDKMIKEK
                     LLVKLDKSKLVGLDNIGQEFLGKSFDPHNDYSIPYFWGTVGIVYNDQLVDKAPMHWED
                     LWRPEYQNSIMLVDGAREILGVGLTTFGYSVNSKHLKQLEAAEKKLQALTPNVKAIVA
                     DEMKGYMIQGDAAIGVTFSGEASEMLDNNDHLHYVVPSEGSNLWFDNLVLPKTMKHEN
                     EAYAFINFIMKPENAAQNAEYIGYATPNTKAKALLPDDIKNDPAFYPTDETVKKLEVY
                     DNLGSKWLGIYNDLYLQFKMYRK"
     gene            31365..32897
                     /locus_tag="TV188_000316"
     CDS             31365..32897
                     /locus_tag="TV188_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HEL1533709.1"
                     /translation="MENHKNEFTFSKHSIIAYVWRGILVGIIAGAIVSLFRLLIEMVS
                     EAVVGYYHQAHSNRMLLVPIAGFSLLAVFLVGLLVKSDANIKGSGIPHVEGELKGLMS
                     PNWWSVLWKKYLGGTIAISMGLMLGREGPSIQLGAMSAKGLAKYLKSSRLEKRVLIAS
                     GAAAGLSAAFNAPIAGLLFVVEEIYHHFSRLVWITALVASLVANFISLNIFGLRPVLA
                     MPKAMPFLALHQYWLLLILGLVLGCLGFLYEEVILHFHRVYDFLGKSLRLAPHFHGLI
                     VVAIILLIGYYLPQLLGGGHGLIMSLSEQKLPLLTVLAYFFIRFLGSMFSYGSGLPGG
                     IFLPILTLGALSGTIFGLILQQIGLLDRQMIPLFLVLGMAGYFAAVSKAPLTGMILVT
                     EMVGDLKPLMAIAVVTFVAYLVMDLLNGQPIYEAMLEKMAIKHPTDLVEPTLIELPVS
                     EKIAGRYVRDLKLPKNVLITTQLHHKKSQVVSGDTLLISGATIFLVVNEADTGFVREV
                     LM"
     gene            33103..33717
                     /locus_tag="TV188_000317"
     CDS             33103..33717
                     /locus_tag="TV188_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HEL1533710.1"
                     /translation="MLEVISKELRHYQKNKLAAYQKKNQGIEAGGIVFAGDSLIEFFP
                     LKKYFKQVSTIYNRGIAGIDSQWLLEHIDSHVNDLEPSHVFILIGCNDIGLGFDQSHI
                     VSTIVDLISRIRSQSIYTRISLLSLLPVSENPAYQATVKLRTNRAIDEINQALAMIPA
                     IEFIDLNACLKDETGGLAAAYTVDGIHLNALGYEHLAQAISPYL"
     gene            34065..35192
                     /locus_tag="TV188_000318"
     CDS             34065..35192
                     /locus_tag="TV188_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEL1533711.1"
                     /translation="MKFEKKQVFYVVLAFVLCYAIQANWDNGANIVTTVYKTSLPFLY
                     GAAVAYIVNIVMSAYERAYTYTLKPFPFAMKARRGLCMLLAYFTFISLIVWIISIVIP
                     DLIASISSLTQFDTRAIKEVISDLGHNKLIARAINYIGGDAKLTETITNYSQQLLKQF
                     IGVLTGILTSVTAVASAIINVVISFVFSLYVLASKEELCQQATTLIDTYTGKYAKAIH
                     YLVGLLHSRFRGFFVSQTLEAMILGSLTAIGMFILQLPFAGTIGVLVAFTALIPVVGA
                     SIGAAIGFVLIMTQSMSQAVVFIVFLVILQQIEGNFIYPRVVGGSIGLPAMWVLMAIT
                     IGAALKGIVGMIVAVPLAATLYQVVKDHIHKKQALQNRQSS"
     gene            35344..36021
                     /gene="radC"
                     /locus_tag="TV188_000319"
     CDS             35344..36021
                     /gene="radC"
                     /locus_tag="TV188_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEL1533712.1"
                     /translation="MYSIKTDHKLMPRERLIRLGPEKLSNQEQLAILLRTGNKEKHVL
                     ELSAYLLSSLDSLADLKKFSLQELQRLSGIGKVKAIEIKAMLELADRIQIAGQAVADP
                     VLSSAQVAEKMMIELGDKQQEHLVAIYLDSQNKIIEEKTIFIGTVRKSIAEPREILYY
                     ACKNMATSLIVVHNHPSGLTKPSANDYHFTEKIKRSCDYLGLICLDHIIVSKYDYYSF
                     REKSDLF"
     gene            complement(36023..36718)
                     /locus_tag="TV188_000320"
     CDS             complement(36023..36718)
                     /locus_tag="TV188_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEL1533713.1"
                     /translation="MSKTIIGITANQRGTKALDNLPCSYAPTSFIEAVTRSGGLPLLL
                     PIGDEAAAKSYVAMVDKIILIGGQHVDPKYYHEKRAALDGDFSPQRDIFELAIIKEAL
                     AQKKPILGICRGMQLINVALGGSLNQHIEGHWQKTASDCLSQEIVIEKTSPLYPIYGP
                     RALINSFHHQSLKQVAEDLRVIARDPNDGTIEAVISCNPDIPFLGVQWHPELLQAIRE
                     EDLRLFDWFIHSF"
     gene            complement(36730..37374)
                     /locus_tag="TV188_000321"
     CDS             complement(36730..37374)
                     /locus_tag="TV188_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEL1533714.1"
                     /translation="MVIDKSIPKATAKRLSLYYRIFKRFYADQVEKASSKQIADAMGI
                     DSATVRRDFSYFGELGRRGFGYDVTKLMNFFADLLNDHSTTHVILVGCGNIGRALLHY
                     RFHDRNKMQIVMGFDTDDNPMVGTKTPDDIPIYGISTIKEHLDNSGIETAILTVPSIY
                     AQEVADQLIEAGIRGILSFAPLHLQVPKGVIVQSVDLTSELQTLLYFMNQNHLD"
     gene            complement(37660..38007)
                     /locus_tag="TV188_000322"
     CDS             complement(37660..38007)
                     /locus_tag="TV188_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEL1533715.1"
                     /translation="MAFEKEIALKDCKYSYRISPKIKKYTLRDTTFSQTKIGHYQLTR
                     LLEKVPNSGEGFPLKITINKDLDGFKLAITDQSGLRLVNIFKSEEHSILQDKFYFLMD
                     SLVERDIFIKKEC"
     gene            complement(37997..39124)
                     /locus_tag="TV188_000323"
     CDS             complement(37997..39124)
                     /locus_tag="TV188_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1533716.1"
                     /translation="MIYFDNAATTSLSQAAIKAMTEAMADDFGNPSSIHAYGRQANKQ
                     LRECRKAIANCLGAAENHIIFTSGGTESNNTAIKGYALAHQEKGKHLITTAIEHHSVL
                     STMAYLEERFGFEVTYLEAKNGIIDLNQLQAALREDTILVSMMFANNETGDLLPIQAV
                     GSMLKQHQAVFHVDAVQAIGKVPIQPADLGIDLLSASAHKFHGPKGTGFLYNKGLKLA
                     PLLHGGNQENKQRAGTESLINIVGMTQALDEAVSRLPQHYQHAKELSQLLLSELEGIS
                     YQLNHNECHLPYIINIGFPGYQNHVLLTQLDLAGFAVSSGSACTAGAVEPSHVLAAYF
                     GKQSHRLTEAIRVSFSEQNTQKDVIALATQLKNILGGSYGI"
     gene            complement(39127..40101)
                     /locus_tag="TV188_000324"
     CDS             complement(39127..40101)
                     /locus_tag="TV188_000324"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1533717.1"
                     /translation="MTERYADKQIKLFSLTSNLAIAEKISKAAGIPLGKVSSRQFSDG
                     EIMINIEETVRGDDIYIIQSTSFPVNDNLWELLIMIDACKRASANTVNIVLPYFGYSR
                     QDRVAKSREPITAKLVANMLTKAGIDRVVTLDLHAVQVQGFFDIPVDNLFTVPLFAKH
                     YYPLGLSGPDTVIVSPKNSGIKRARSLAEYLNSPIAIIDYAQDDAEREEGYVIGDVAG
                     KKAILIDDILNTGKTFAEAAKILECAGATDIYAVASHGIFAGGAADILETAPIKEIIV
                     TDSVKTKNRIPKTVTYLSASDLIAEAIIRIHERKPLSPLFSYKPESTN"
     gene            complement(40236..40808)
                     /locus_tag="TV188_000325"
     CDS             complement(40236..40808)
                     /locus_tag="TV188_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEL1533718.1"
                     /translation="MTNLEIEYKTLLTKDEYNRLLSQMTHVPPVTQTNYYIDTDHFDL
                     KAHKMSLRIRTFVAAPAELTLKVPEKVGNREYNLELDDTQAKAIIQTGQLPKSAILDI
                     ISTLDVDLSAIKTFGNLTTIRREADTPIGKLALDYNQYAGIKDYELELEVTDPVRGKV
                     DFDHFLAQHQITFKYSKSKVARFSKTLKKS"
     gene            40903..41574
                     /locus_tag="TV188_000326"
     CDS             40903..41574
                     /locus_tag="TV188_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEL1533719.1"
                     /translation="MALDWEEFLDPYIQTVGELKIKLRGIRKQFRKQNRYSPIEFVTG
                     RVKSVESIKEKMALRGVLEENIAQDIQDIAGLRIMVQFVDDIEDVLSLLRQRQDMTIV
                     YERDYIRNMKSSGYRSYHVVVEYPVDTIEGQKKVLAEIQIRTLAMNFWATIEHSLNYK
                     YGGDFPEEIKKRLEVTAKIALELDEEMRKIREDIREAQLLFDPVTRHLSDGVGNSDDT
                     DELYR"
     gene            41549..42385
                     /locus_tag="TV188_000327"
     CDS             41549..42385
                     /locus_tag="TV188_000327"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEL1533720.1"
                     /translation="MTQMNYTDKVKRVAIIANGKYQSKRLASKLFGVFKDDPSFYLSK
                     KNPDIVISIGGDGMLLSAFHMYEKELDRVRFVGIHTGHLGFYTDYRDFEVDQLIANLR
                     RDTGEQISYPILKVVITLDDGRLFKARALNEATIKRIEKTMVADIIINNVKFESFRGD
                     GISVSTPTGSTAYNKSLGGAVLHPTIEALQLTEISSLNNRVFRTLGSSVIIPKKDKIE
                     LVPKRLGVYTVSVDNKTYHLKNVVKVEYFIGNEKIHFVSSPSHTSFWERVKDAFIGDS
                     ES"
     gene            42382..43284
                     /locus_tag="TV188_000328"
     CDS             42382..43284
                     /locus_tag="TV188_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1533721.1"
                     /translation="MRFEFVATKKTKVKTLLKEHDVSKGLLAKIKYKGGNIWVNGVAQ
                     NAIYLLDIGDVVAIDIPNEESFEQLTAISHDLDIVYEDEHFLILNKPAGYASIPSAIH
                     SNTIANFIKAYYIKQDYPNKQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQQRAIN
                     KRYYALVCGQERLPDQGEIIAPIGRTDDSIITRTVTPKGKYAKTSYKVIARYPENVSL
                     VDITLHTGRTHQIRVHFAHLGFPLLGDDLYGGRLDLGMTRQALHCHHLSFTHPFTESR
                     SDHTICLTDDFESVIIDLQKKDRG"
     gene            43288..44289
                     /gene="pta"
                     /locus_tag="TV188_000329"
     CDS             43288..44289
                     /gene="pta"
                     /locus_tag="TV188_000329"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEL1533722.1"
                     /translation="MSIRNLFGGLREKIVGKNMKIVFPEGNDERVVRAAARLKFEGLV
                     EPIILGQADDIRSLLTQLGFAEQHYTIINPNDYADFEKMKAAFVELRKVKATLEDADR
                     LLRDVNYFGVMLVKLGLADGMVSGAIHSTADTVRPALQIIKTKPGISRTSGVFLMNRE
                     NTEQRLVFADCAINIDPTAQELAEIAVNTADTAKIFDIDPKVAMLSFSTMGSAKAPQV
                     EKVQEAVRIAKELRPELALDGELQFDAAFVPSTAAIKAPDSSVAGHANVFVFPDLQSG
                     NIGYKIAQRLGMFDAIGPILQGLNKPVNDLSRGSSAEDIYKLAIITAAQALENESIN"
     gene            44389..45147
                     /locus_tag="TV188_000330"
     CDS             44389..45147
                     /locus_tag="TV188_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1533723.1"
                     /translation="MTKIALVTGASAGFGKAIAEQLIAQNIKVIGAARRIEKLRELEG
                     IFGSERFYPLQMDVSEPTAIDKALAELPKEWQAIDILVNNAGLALGLDKAYEADVANW
                     LTMINTNIIGLIYLTRQVLPQMVSSNNGMIINIGSTAGTIPYPGANVYGASKAFVKQF
                     SLNLRADLAGTNIRVTNIEPGLCEGTEFSHVRFKGDHERVKALYAGAHAIQPRDIANT
                     VSWIIDQPEHVNINRVEMMPVSQSYGSQPVSRHD"
     gene            complement(45252..45938)
                     /locus_tag="TV188_000331"
     CDS             complement(45252..45938)
                     /locus_tag="TV188_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HEL1533724.1"
                     /translation="MTKTIYTLALVDDKNNLQKTFFTTLSQEFSYLFHITIVRQLTTE
                     QLKKAQAIFTFQNLEASLPVLYFNQADKEQGFTVSDHTFTDSQQTLRLAKYLMQFYQA
                     LAPHFLTYLPLQARIADHQGQIIFDNHRFNGNFFASDKHDVIEDWILTDLHKAATGSK
                     LYLIPTASQDHIYMQQYQALYDDTKQFVGVYDMILDFKPMLQHYLEETGQAIVGWSDV
                     TSGPSLSDHF"
     gene            46193..46921
                     /locus_tag="TV188_000332"
                     /pseudo
     CDS             46193..46921
                     /locus_tag="TV188_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922297.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            46914..48446
                     /locus_tag="TV188_000333"
                     /pseudo
     CDS             46914..48446
                     /locus_tag="TV188_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_028398951.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
     gene            48804..49787
                     /gene="guaC"
                     /locus_tag="TV188_000334"
     CDS             48804..49787
                     /gene="guaC"
                     /locus_tag="TV188_000334"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEL1533725.1"
                     /translation="MFNDMPVFDYEDIQLIPNKCIINSRSEADTSVRLGNYTFKLPVI
                     PANMQTIIDETIAEQLARDGYFYIMHRFDEEGRKPFIQRMHEQQLIASISVGVKDYEY
                     DFVSSLKEDAPEFITIDIAHGHADSVIKMIKHIKAELPETFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAAVRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGATMVMIGSLFAGHIESPGKMVEIDGQSFKEYYGSASEYQKGEHKNVEGKKIL
                     LPTKGHLADTLTEMKQDLQSSISYAGGRDLESLRRVNYVIVKNSIWNGDSI"
     gene            49973..50554
                     /locus_tag="TV188_000335"
     CDS             49973..50554
                     /locus_tag="TV188_000335"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEL1533726.1"
                     /translation="MRLLEERILADGTVLGETILKVDQFLTHQVDYRLMKEIGRVFAD
                     QYADLGITKVVTIEASGIAPAVYTAEALEVPMIFAKKHKNITMTEGILTAEVYSFTKQ
                     VTSTVSIAGGLLSKEDRVLIIDDFLANGQAAKGLIDIIHQAGAKAVGIGIVIEKSFQA
                     GRQLLEDLGVEVTSLARIKHFDNGIVSFLEADA"
     gene            complement(50842..>51407)
                     /locus_tag="TV188_000336"
     CDS             complement(50842..>51407)
                     /locus_tag="TV188_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1533727.1"
                     /translation="DQSLGSIFLKEKGMSIDLGALAKGYIADKLMAFLIKDGITAALI
                     NLGGNVLVHGTNKQRHNGLFYVGIQQTNQKRGQHVGVIKVNNKSVVTSGIGERQLQIK
                     DKTYHHLLDPHNGYPIKTNMASLTIVSQFSLDGELWSSRLFGLEHSFVLSQLNKLPEV
                     EGIIITKDGQVTISDGLKGAFRLHYKH"
BASE COUNT        14499 a         9749 c        11793 g        15366 t
ORIGIN      
        1 ggaaattcta tatcaattgc ttgacattgt agggaaagtc ctctatcatg aatttgctgt
       61 atcgctttta tgatgtacaa tcaggcctca ttacagttga tgggcaaaat attcaggagt
      121 attctagaga aagcctgcgt tcacagatgg gtattgtctt gcaggatcct tatttgttta
      181 caggaacgat tgcttctaat atcacgatgg gaaatccagc ttattcggat caggatattt
      241 tagatgcttt ggaaaaggtc ggagcctctt cgatgattgc tcgtctggaa aagggcattc
      301 atgagcctgt ctatgaaaaa ggctcctctt attcaagtgg cgagcggcag ctaattgctt
      361 ttgctaggac attgattgcc gaccctaaaa ttttgatctt agatgaagcg acctcgcaca
      421 ttgatactga gacagaggac atcattcaac aggctatgga ggtcttaaag aaaggccgaa
      481 caacctttat cattgcccat cgcttgtcta ccattcaatc tgctaatcaa attttagtat
      541 tggataaggg gaggatcgtc gaaagaggaa cacatcagga attgctagat cagcaaggca
      601 tttatgctga aatgtccaag ctacaagaaa aggtggctgt acagtaatgc tttttagtga
      661 tagctatcaa aaaattcctt ttctaggccg tgttaagcag cagtagtctg tgaagtagga
      721 gctatattta ggttttgtgc ctaagccttt aaggttttta agaggctgga ttagggctta
      781 acatcaataa aatcatatgt cactttatca cagcatgttg tggtgaagtg ttttttgtgt
      841 cgtcctgcta aagggaagat cctcacagtc agggcttggc tggctccttt atcagagtca
      901 gatcattcat acgtacttcc tgtcaggctt ggctaagttg aattgtatgt tgagatcagc
      961 atgtcagcaa tttatgcttt gtgtctgact tttagcagct tgtacatgaa ataggactaa
     1021 aggacacttg aattgatgaa gaatcagctt aaaaaccatt tgtcctagat aggataagaa
     1081 ctgtctaaaa gggggataga tcatcgcaat ttttaacaat ttagtgtaaa atagtaaggt
     1141 gaatgttttg atgaaataaa cgaaaagatt taggatatga ataagacaat tggatatggc
     1201 aaggcacaca gcaaaatcat tttaatgggt gagcattctg tggtctatgg ctaccctgcg
     1261 ttggccttgc ccttaaaaga tattgaagtg acctgccgga ttttccctgc tgcaaagccc
     1321 ttagcctttg atttttatga tcccttatca acggcagttt atgcagcctt ggagcatttg
     1381 gggtgcttgg cagagcccat tcattatgat attatgtctc aggtaccaca aaagcggggc
     1441 atgggctcct cagcagctgt ttcgattgca gctgttcgag ctgttttttc ttattttggg
     1501 cagcccttgt cagatgagct gttggaaatc ttggtgaata aggcagaaat cattgctcac
     1561 accaatccca gtggcctaga tgctaagacc tgcctcagtg ataaggccat caaatttatt
     1621 agaaatgttg gttttgatac cattgatatt cagttaaatg cttatttggt cattgctgat
     1681 acagggattc aggggcatac gcgtgaggct gtcaataagg tggctcaatt tgaggaggaa
     1741 aatcttcctc atttagccaa gcttggctgt ttcacagagg ctgttgagca agcaattaag
     1801 acaaacgatt gcctagctat tggacgattc atgacgcagg cacatgaatc actaaaggct
     1861 attggtgtca gtgtggcaaa ggctgatcag ctggttgcag cagctcttga ggctggcgct
     1921 ttaggagcta aaatgactgg tggtggctta ggaggatgta tgattgcatt agctgaaagg
     1981 ataacagacg ctcagcaaat cagtaagaaa ctaaaagaag agggagctgt aaatacgtgg
     2041 attcaaatac tgtaacggta acttcctacg ctaatattgc tattgtcaaa tactggggga
     2101 aaaaagatga ggctaagatg atcccatcaa cctctagtat ttctttgacc ttggaaggca
     2161 tgtacacgac aacaagtctt tcttttttgc ctgcctcagc aaagggagat cagttttata
     2221 tcaatggtgt tctgcaggac gccaaggagc atgctaagat tactgcgatt ttggatcagt
     2281 tccgtcagaa ggaccagact tttgtcaagg ttgaagccag caacagcatg ccaactgcgg
     2341 caggcttatc ctcaagctct agtggcttat ctgctctggt aaaggcctgc aatcagcttt
     2401 ttcaagctaa gctaagtcaa gaagagcttg cccaaaaggc taagtttgcc tctggctctg
     2461 cttcgcgttc tttttttggc cctgttgctg cctgggataa ggatacaggc tctatttata
     2521 aggtcaaaac agatttaaag ctggccatga ttatgctggt cttgaacgat gctagaaagc
     2581 ccatttcgag tcgagagggg atgaagcgct gcagcacaac ctcaacaagc tttgaccagt
     2641 ggctggccca gtcagaaagt gattatcagg ccatgttgcg tgcccttagt gacaatgatt
     2701 ttgaaacggt tggttggctg acagaagcaa atgctctagc catgcacgca acgaccaaaa
     2761 cagccagtcc ttccttctct tacctaacag aggcctccta tcaggccatg ctaagggtca
     2821 aagagcttcg tcaagagggc tattcttgct attttacgat ggacgctggt ccaaatgtca
     2881 aggtgctttg tttagaagag gacttagagc ggctgtcgca cctttttgaa agggagtatc
     2941 gtatcatcgc ctcaaaaaca aaggaattac cagatgtcta aatatcatgt tcaagcagga
     3001 ggaaagctgt atctgacagg cgaatatgcg attctaaggc cggggcaaac ggcgttgatt
     3061 tgctatattc ccataatgct gacagctgtc attgaagcag cagaggctgt tagtatcagc
     3121 tcagatatgt ttgaccatgc tgctgatttg tcaccggata aggattatag gctgattcaa
     3181 gcctctattg aagcctttag tttatatata gataaggata ttaaggagct gccagccttt
     3241 tctttgtcta ttactggtaa gcttgagcgt gacggtaaaa agtttgggat tggctctagc
     3301 ggtagtgttg ttgtactaac gctaagagct ttggcagcct tttatcaggt tcagctgcta
     3361 ccagagcagc tctttaagct ggctgcttat accctgctta aatcaggaga taatggctcc
     3421 atgggggaca ttgcctgcat tgcctatgag agcttggttg cttatacatc ctttgatagg
     3481 cgtaaggttg gtcaatggtt gatcgagatg accctaaaag agctaatggc agcacattgg
     3541 gggtatacga ttgagactat tgagcctgct ctgccctgtt ggtttcttgt tggctggacc
     3601 caagtccctt ctatctcaag agagatgatt cagctggtta acaagagcat tagctgtcag
     3661 tttttagagc aaagccagct ggtcacacag gaagtgatga ctgccctgca gcttggtcaa
     3721 agaaaaaggc tcaaagctag cattgaaaaa gcgggtcagt tgctgcaagg gttggcttca
     3781 gttatttatc accctaagct tacgcagctt gtccaggctt gtcaagggct tgatgctgct
     3841 gccaaatcat caggctcagg aggtggggat tgtggtattg cactcgtttt tgaggctaag
     3901 gacattgagc ctatccttgc cagatggcag caagcaggga ttgtattact atatcaggag
     3961 gaatggggat aaacatgact aatcgtaagg atgaccatat cacacatgct ttgagctatc
     4021 attctcctta caatgcattt gacgacatgg agctcattca ctgttccttg ccgagctatg
     4081 atttagctga tattgatctc tcaacccatt ttgctggctg tgattttgag tttccttttt
     4141 atatcaatgc gatgacaggt ggtagcaaga aaggccaagc agtcaatgaa aagctggcca
     4201 aagtggctgc ggctacaggt attttaatgg tgacaggctc ttacagtgca gccttgaaaa
     4261 atcctgagga cacttccttt caattgcgag gtgtagcacc agatttacag ttggccacca
     4321 acattggtct tgataaggct gttgacctag ggattagagc tgtcgaggaa atgaagccct
     4381 tgtttttaca ggtacatgtg aatgccatgc aggagctgtt aatgccagag ggagagcgca
     4441 gctttaagca ttggaaggat catttagcgg cctatgccaa gcagcttcca gtccctttga
     4501 ttttaaaaga ggttggcttt ggtatggata ttaagaccat cactatagca cgtgatatgg
     4561 gagtaaaaac ctttgatatt tcaggaagag gaggaacctc ctttgcctac atcgaaaatc
     4621 aaagaggaag taatcgctct tacctagacg attggggaca gacaacagtg caatgtctat
     4681 taaacgccaa aggtctggtt gatgaagtgg agatcttagc ctcaggtggt gtcagacacc
     4741 ccttagatat ggttaaatgc ttggtgctgg gggcacgtgc tgtgggccta tcgcgagtgg
     4801 tattggagtt agttgagacc tatccagttg agcagatcat cgctacgatc aatagctgga
     4861 agaaggagct taagctcatc atgtgtgctt tagattgtcg aaccttgagc gatttgcgtc
     4921 aggtggatta tttattatat ggtaggcttt atcaggcaaa ccgctaaaga ctttttagcc
     4981 ctgagctaac tttccttaga aaatcatcac aggagttaag aagctgcctg cttggtgctg
     5041 caagctaatt cagctgatta tggctcgtaa gatttttaga tgtctgaatg aaatgatagg
     5101 acagatgaca tagtatagcg ctaatttcta gtgaaaatca gtccttggtc aggttactga
     5161 gactgaggtt aagtttatgt ttacactaac acttaaagga tatgaaaaca cttggtagct
     5221 gccactgaag ctgttaccaa gtgtttttag tctatgattg gcttaatcgt atggctgtta
     5281 agagctgtcc tgccttttct aggttcattg gcttatcctt tagtagagcc ttaactagtt
     5341 gaggcacctc ctgctcacta gcacctgcta atagagctag agacttggcc tgcagcttca
     5401 tgtgaccagc ctggatacca gttgaggtca aagcctttag agccgcaaaa ttttgcgcca
     5461 gcccaactgc agtggtgatt tgggcgagaa ccttagcatt tggttgctct aaaaggctat
     5521 gagcaacact gacggttggg ttgagaccga tcgaccctcc tttactagca atgggcattg
     5581 gcagtgttag ctctccgcat aagctatttt tagataaatc aacgtgccag ctacttagcc
     5641 ctctataaga gccagtcctt gcggcatagg catgtgctcc agcctcaata gctctccagt
     5701 catttccggt agctatagct accgcatcga ttccattaaa gattccctta ttatgcgttg
     5761 ctgctcggta agggtcaatc tgggctaatt tgcttgccag ctctattttt ttggccaatt
     5821 gctgagcttc ttccttatgt cgacttaggt atctgaggtc aacctgacat ttagcactaa
     5881 ctaaagcttt tgttgcatag tttgagagga tagccattaa gcattgacca ccgcttaggg
     5941 cctccaaatc aggtactaaa gcctccatca tcgtgttaac gatgttggct cccatagcct
     6001 cttgggtatc aacgctcaga tagacaatga aaaaatcctc cttacgctca acggtaaggc
     6061 tctttgcgcc accaccacgc ttaacaatag aagggtaggc attgtttgca acgtcaatca
     6121 atgtatctgc gttagctaga atagccagcc tagcctgctc gtcatcttta acatcataaa
     6181 gagctacctg cccaagcatt tgacgactga gtacctcagt ctgaaagcca cctgatcgct
     6241 tgatgatttt ggcagcaaag gaagcagcag caacaacaga aggctcttca gtcacaaagg
     6301 ggacctgata ggtatgccca ttgatcagaa aatcaggggc tagactaaaa ggcagagcca
     6361 gtcgaccgat gacattttcg gtcatttgat tggcaatagc aatgggtaag agctggtctg
     6421 tctctaacag cttttgctgc tgcgggccaa gcagctggtc atctgcgagc tgttgaatgc
     6481 gttctgcaag gcttttttta taaaagccgg cccaatttgg tttagttttt gtcatcatct
     6541 tgataaattc gttggtgttc cttaatttct ttgagggcaa acctgccagt tagatatggt
     6601 gaaaagctgg cattgccatc ttggtctagt ctaggctctt cataaaaaag tgcttcataa
     6661 tcagccactg aaatcacctg acgttggtct aatagggctt gtcgattagt cagtagcatg
     6721 tccttgtaac cgtcaacaag ctgccctgaa aacagctcac taacagctcc tgagccatag
     6781 ctaaacaatc caatcctatc accagccctt agcacctgac tattctctaa aagtgataat
     6841 aagccgaggt agagtgagcc tgtgtaaatg ttgccgattt gcttgctgta ggcaatagaa
     6901 gcttgaaagt tttcataaag cctttctttg tgatcatctg ctagtgattt tgtcatgatc
     6961 ttatgaagtc cctttagagc aagctttgga aaggggatat gaaaacaaac agcagcaagg
     7021 tctgatagct caataccttc tttttcttgg tatttgtccc aggttgtttt tagggaatca
     7081 aggtattgct tggtcgaata aataccattg acaaatggtg ttgagctgta atttggacgc
     7141 caaaaatcca tcacatcacg tgtctgtgcg acattgtcat gatttaactg gagaatacga
     7201 ggattagtag taactagcat agcaatactt ccagcacctt gtgttggctc tccggcggat
     7261 ccaatgccgt atttggcgat gtcactggca atgaccaaga ccttggaggc tgggtgtgca
     7321 gcaacatgta atttggcata atctaaagca gcagtagcgc tgtagcaggc ttcctttatc
     7381 tcaaaggagc gtgcaaaggg ctgaatatca agcagctgat gaacgtaaat actggctgcc
     7441 tttgattgat caatgcttga ttcggttgct aaaatgacca tgtcaatgct tgctttatcg
     7501 tctttggtaa ggatttggtc agcagctgat gcagcaagcg ttacaatatc ctctgtaaca
     7561 ggtgcaatgc ttagagcgtc aagcattagc ccctgatgaa attttgctgg atcagtgctg
     7621 cgagcaagtg ccaggtcttc catttttaag acgtattgac tggtcgcaaa gccaatctta
     7681 tcaattccga tgttcataaa tatccttctt ttatccattt tatagtccta tccattttat
     7741 catattttct tagaaaatta gctgatttaa tacgatagtt ttacctttca aaccaaaaac
     7801 agcagcatat agctttcttc tggtattttt gaaggaaatt agataaaata atatggactg
     7861 tgcttacaga aaggggtttc catgacaaaa gcagatcata tttttaaagc taatatcaaa
     7921 aaaattatgg aggagggagt ctttagcgag caggctcgcc caaggtacaa aaatggtcaa
     7981 acagccaatt ccaaatacat tacaggtgct tttgcagagt atgatttgtc taagggagag
     8041 tttcctatta caactctaag atcaatccct atcaagtcag ctattaaaga gttattttgg
     8101 atttatcagg accaatcaaa cagccttgat gttttagaaa acaaatacaa cgttcactat
     8161 tggaatgagt gggaggtcgg tcagacaaga accatcggtc agcgctacgg tgcaatcgtt
     8221 aaaaagcatg atatcatctc aaaaatcctc aagcagctag aggacaaccc ttggaatcgc
     8281 cgaaatgtga tttctctgtg ggattacgaa gcctttgaag aatcagaagg actgctacca
     8341 tgtgcctttc aggtgatgtt tgatgttagg cgagtagatg gtgagctgta tttagatgcc
     8401 acgctgaccc agcgctcaaa tgatatgcta gtggctcatc atatcaatgc catgcaatat
     8461 gttgccctgc agctaatgat tgccaagcat tttggctgga aggctggtaa gttcttttat
     8521 tttgtcaata atttgcacat ctatgacaac caatttgcgc aagccaagga gctattggag
     8581 cgtcagccag cagcctgtca gcccaagctt ttgctgcatg ttcctgatgg gacagacttt
     8641 tttgatataa gaccagagga ttttgagcta caggattatt acccagtgaa gcctcagctc
     8701 acctttgact tggcgattta agcgaaaaag acgatttttt ctgagcattt tgccaagaaa
     8761 tttgatagaa taaaagaagt tcatattgag gaaagctagt gatgacaaag aagattattg
     8821 ctatttgggc agaggatgaa gcaggactta tcggagcgtg tggcaggctt ccttggtacc
     8881 taccaaaaga gttgcagcat ttcaaggaaa caacattgaa tcaagctatc ctgatgggac
     8941 gagtaacctt tgagggcatg aagggtcgtt tgctgccaaa tcgccaaacg cttgttatga
     9001 ccagagacag ttattatcat gtggagggcg ctttaaccat aaccagtgtg caggaggctt
     9061 tggattggta tcatgcgcag gataagacct tatatgtgat tggtggcagc aaggttttag
     9121 aggcctttga tggttatttt gatgtcatca tcaaaacagt ggtacatcac cagtttgagg
     9181 gtgataccta ccgacctagg ttagagctga gtgattttgt agaggagacc tctgtattgt
     9241 acccaaggga cgataacaat ccttacgatt tcactgttac agtattgaga catcgctaat
     9301 atagggagat gatagtctat gcagcgtagt atttttgggg tatttacggc ctttttgtgt
     9361 gcgatttgtg ttttatgtgc cataccggcc tttagaaaaa atcgctatgg cttaggatta
     9421 ctttttttat taaatgcctt tactaaccta gtgaatacca tacatgcctt ttatggaaca
     9481 ctgttttaag cctaagagaa tgaaaagaga aagatagagg aatcatggca ggaaatcgta
     9541 gtaacgatat taaggttcat tgctcgtttt gcggcaagag ccaagacgaa gtgaaaaaaa
     9601 ttattgcagg taataacgtc tttatttgta acgaatgtgt tgccttatca caagaaatca
     9661 tcaaggaaga attggcagaa gaggttctcg ctgatctgac tgaggtacca aagccaaaag
     9721 agctgcttga gattttaaat caatacgtca ttgggcagga gcgtgctaag agagccttat
     9781 cagttgcagt ttacaaccac tacaagagga tttcatttac tgagagtcgt gatgatgatg
     9841 atgtggattt gcagaagtcc aatattctga tgattggacc aacaggctca ggaaagacct
     9901 ttttggcaca gaccctggct aagagtctga atgttccgtt tgctattgct gatgcaacct
     9961 ctttgactga ggcaggctat gtcggagaag atgtggaaaa tatcctcctg aaattaattc
    10021 aagccgctga ttacaatgtt gagcgtgcag agcgcggcat tatttatgtt gacgaaattg
    10081 ataaaatcgc taaaaaaggt gagaatgtct ctatcactcg tgacgtatca ggagaaggtg
    10141 tccaacaagc cttgctaaaa atcattgaag gaacggttgc tagtgttcca ccgcaaggtg
    10201 gtcgtaagca cccaaaccaa gagatggtac agattgatac caaaaatatc ttgtttatcg
    10261 tcggaggcgc ctttgatggt atcgaagaaa ttgtcaagca gcgcttggga gaaaagatca
    10321 ttggctttgg gcaaaatagt cgaaagattg atgacaatgc ttcctatatg caggagatca
    10381 ttgctgagga tattcaaaaa tttggtctga ttcccgaatt tattggacgc ttgcctgttg
    10441 tggcagcgct tgagcagctt aatactgagg atttgattcg tattttaaca gagcctagaa
    10501 atgcccttgt gaagcaatat caagccttat tgtcatatga tggcgtagag cttgagtttg
    10561 aaaagggggc tctggaggct attgcaggta gggctattga gcgcaagact ggtgcgcgtg
    10621 gtctgaggtc tattattgaa gaaaccatgc tggatatcat gtttgaggtg ccaagccaag
    10681 aggaagtaat caaggtacgc attactaagg aagctgtcga aggtcaatca aagcctattt
    10741 tagagatagc ctaaggaggt atgatgtctg aagagcaaat ccttaacacg cataatgctt
    10801 cgatattgct tagtgcggca aataagtctc attacccaca agacgacctt cctgagattg
    10861 ctttggcagg tcggtcaaat gttggaaaat caagctttat caatactata ctaggacgta
    10921 aaagccttgc tagaacctca agcaaacctg gtaaaactca gcttcttaat ttttttaacg
    10981 ttgatgataa gctaaggctt gttgacgttc ctggctatgg ttatgctaag gtatctaagg
    11041 cagagcgggc tagatgggga aagatgatcg aagagtacct gaccacacga caaaatctca
    11101 gagcagttgt tagtctggtt gattttcgcc atgagtcatc acaggacgac attcagatgt
    11161 atgagttttt gaagtattat gagattccgg tgattattgt ggctacaaag gcagacaagg
    11221 ttcctcgtgg tcgctggaat aagcatgagt ctatggttaa aaagtcctta aactttgatc
    11281 aaacagatgc gtttattatt ttttcatctg ttgagcgtat cggtattgat gagtcttggg
    11341 ataccatttt agagtattta taagcatatg gtaaaaaatt taagtatctt ttagacaggc
    11401 acttgtgtct ggtctgagag gtgctttttt attgacaaaa aaacaatttg ttgatgacga
    11461 gcttgtgttc aaaaatgtca gtttgctaaa aaatgatgat aacaaacaag acttttatga
    11521 tataatgctt agcaggataa tatggagaca tgagaaaaag gtcagagaca gctaatttgc
    11581 tatccctgat tataactatg atgaccagca ttattataat actcatggtg ctagctatta
    11641 gtagcagcac ctaacctata gtgttgcttt ttaggttaca agcactggcg ctaggagtat
    11701 tataatatat ttagaaaggt ttttttatga caataaaaaa atgccctcaa atacttgcct
    11761 tattccttgc ttttgcagcg ctagctagtc aggggcaaac cgtccatgct ctggagcggc
    11821 aggagacatc tgtcaagcaa gctcatgaat cagatgattg gtttgatgag gacgaaggag
    11881 ttagcgatat caagtctaat acccctacag agatagactc aacagtaaca gagttatttg
    11941 gtgatgctga gcctaagact aaggctgaaa aagaagagtc aaaagctcca agccctaagc
    12001 aagaagcact gccagcagag tctcaaaaag aaaaagagac atctgctaaa tcgactgacc
    12061 atgcgacagt acaagcagaa gaggcacagc ctgagcaagg ctcagatagt ccttggctag
    12121 cagatgactt tgttactaag ggagatacct tggttgggct atctaaggca ggtcttgcta
    12181 agttatcaaa gacacctgtc ttggtactac caaggatagg gattgacaag acagtgttga
    12241 caaggattgc tagctttgcc tttactccaa ataaatcagt cgctattgct gattatacag
    12301 gtagagcagg tgaacatggc gagatcaatc atctggacgt cgaaggcaga gatatcctta
    12361 ctgagggaga ggattttggt gcctatgcga ttaaaaagct tgtgattcct gaaggctatc
    12421 tttttatcgg tcaagatgcc tttaatgaca ataaacagct agaagaaatc agtctacctg
    12481 atagcttact cagtatttca gactatgcct ttgctcacat gagtttatct aagcttaagc
    12541 tgccaaaaag cctacagtcc attggagatc aagccttttt tgataatcgg attgcaggca
    12601 ctttggtatt gccaaaagct ctaaagcagc tgggagaacg cgtctttaag tccaatcgcc
    12661 tcactggact tgtctttgag ggagaaggct tgtctgtcct aaaagaagca gcctttcaag
    12721 acaatgcttt cattagtctt gttatcccag atagcattca agccttagaa gaggacgtct
    12781 ttacaggaaa ccttggcgat gaagaatacg gtaatcatgc cgttttacga accaaaaatg
    12841 gtcagaatcc ttacagactt cacagtgcca atgttcttgt caatccaagt gatcaggcta
    12901 gaacaccaca gccaccaatt gattacaaca ggtggcttgc agaagatttt acctatactg
    12961 gacagacgat aaccggtttt tcagctagtg gactgcgcaa ggtcaaacgc aataagcatt
    13021 tggttctgcc taagaattat cagggtcagc ccttgacagc cattgcagat aatgccttta
    13081 gaaatgtcaa ttttcatgat aaaaccttgc gtaaatacga cctagaaagc gtgacgttac
    13141 catctaccat tcaaaagatt ggtgcctttg cctttcagtc aaataatcta gaaagctttg
    13201 aggccagcga ggacttggtt gagattggtc aaggagcctt tatgaataat cgcattgaga
    13261 ttctggcctt gaatgataag ctgaaggtca ttggagatgc ggcctttcat atcaatcgga
    13321 tttatgctat tgttatccct gagtcggtcg aagtaattgg catttctgcc tttaggcaaa
    13381 atggtgctaa acatgtgatg tttatgggag ataagctaat aagtattgga gaaatggctt
    13441 ttttgagcaa tactctggag gaagtggatt tgagcagctt agcagggctt aagaccatcg
    13501 ctgttcaagc ctttgcagac aatcacttga gagagcttaa gctgccagat agtttgatgc
    13561 gtattgaagc agaagctttt aaaattaata gacttcaaag agtgaccgtt ccagacactg
    13621 tcattagcat tagctttaat gcctttgatc ataatagtga tgacaaggtt gtcctaagga
    13681 ccaccaatca caataaaaac ctgctagctg atggaaatgg ctttattgtg gatccagacc
    13741 tattaagtgc ggatcaatcg actgttcaag cagttttaga ggacctgcgg cgcttagatc
    13801 tagctagtct acgtgctgat acagcagctc attttatgac actcatcaca agaggtaagc
    13861 agctactaaa agaatccgct gtacggttag gttatcagct taggttcctt gcagagtcac
    13921 gatttttctt agggcgcgtg agactggatc agctgattaa aactgctgac ataaccctat
    13981 ctagccatca agacacacct aatgctaagc tgttgatggc taagctagac aaggccaagc
    14041 tgcattacaa taatagcgca atgactgctc caaaagtaag tcgcttggaa aaagagctca
    14101 gcctgttaat tgatcttgtc caaggggtag gcgctatctc taaagcaaca atgactcaag
    14161 gtgtctataa gcttcagaca accctaccta ttccagagta ttatattggg gttaatcttt
    14221 atactgatga tcaggggaat attttatttg tgcttgacat gagtgatacg attgggcagg
    14281 gacaacttga tgactatggc aatcctattt taaatgttga tgaggataat gaaggctacc
    14341 atgctttggc cattgagtcc ttagcagatt acgaaggcct tacgattaag gatatattga
    14401 ccaaggagct aaatcaattg cctattcgcg atgtcaagca agcaagagag catcgtgttg
    14461 gtctttttat ggcaatcaga gatgctgcaa gggaagctca gcttctacta gaaaagcaga
    14521 gcaaagcctt atcagaatca gccggcaaat ctaatggctc aaaagtagct gactcaggac
    14581 ttgagccttc tgtgacacta tcaaccaata agactaagct gctaccaaaa acaggagcct
    14641 tcaaagaagc ttgggtgaca atgatcggaa tgcttgttct tttggcggct accctactta
    14701 aaggcgatag tcgctacaaa aagaagtaaa taggcttgct tagcaagcac actctagcac
    14761 cagtaaggct tgaggggctt acaaagccta tctaatctag caatagtata ttgccagtgt
    14821 gagctggtgc ttgagcttca aaaaaacaaa agagcctgaa atgactttta ctagcatttc
    14881 aggctctttt tagcttgtga ttcttttttg tgtgaagctt acttctcact tatcgtaata
    14941 gtatcttgat caaggcttgc taataggtgt ttagcagtcg ggtgatccag gtagtaatcc
    15001 gtaatgcggt cacgaatttc ttgttcgatg acacgtctaa gtggacgaac tcccatcgca
    15061 tgatcatagc ccagatcaat caaacgctct ttaacatcgt cagtcacctc aaggctaatg
    15121 ccttttttag caagggtttg gttcacttct gttagcatta aagcaacaat ttcttgtaaa
    15181 tcctttttcg ctaaatggtt gaattcgatg acaccgttga agcgattcaa gaattctggt
    15241 ctaaagtaag gtgcaatacg ctccatgata gcaggctctt gatcagcacg atctcctgct
    15301 tgatggccaa aaccagcatt agaggttgcg atgataaccg tatttttgaa attgatcgtg
    15361 ttgccttgtc catctgtcaa tcgcccatca tcaagcactt gaagaagcag tgtaatgacc
    15421 tgtgggtctg ctttttcgat ttcatcaagc aagatgatag agtaaggact gcgacggaca
    15481 cgttctgtaa gggtattttg attatcatca tagccaacat agccagctgt tgttccgatt
    15541 aatttggaaa cagctgtgcg gtcactatat tcagacatat ctaagcgaat gatagcgtcc
    15601 tttgagccga acatatcaag ggctaactgc ttagccagct cggtcttacc aacaccagtt
    15661 ggaccaacaa agaggaagga gccaattggg cgattaccgt catcaaagcc tgcgcggttg
    15721 cgtcgaatcg cacgagcaac agcctcaact gcaccatctt gtccgataac atggccttta
    15781 agacggttac tgatttcctt gagcctttct aaatcactag cccccatatt tgatactgga
    15841 acaccagtta gacgttcaac agattctgca atatcattaa cagtggcagt gaccttttgc
    15901 ccttcactgt gatgattgat ttgcttttgg agctcctcaa tgcgggtctt agcagttaag
    15961 gccttttcaa agtcttcttc tgcaacagcc ttttcctgta gctccttttg cttagtgatt
    16021 tctgcttcaa gtgattttag atcagtgaca gggtgctgag ctgctagatg agcagcagtc
    16081 atatcaacaa ggtcaatggc tttatctggt aggcttcgtt gtggaatata ttggatagca
    16141 taatcaatag ctgccttcaa gacagagtct ggtaggatca cattgtggtg ctgctcgtag
    16201 aggttgcgaa tgcccattaa aatgtggaag gtatcctctg ctgaaggagc attaacctta
    16261 acctcgttga aacgacgagc aagagcagca ttttttagaa tggtgttgcg atactcatct
    16321 tgagttgtgg caccaatcag ggtcaactca ccgcgtgaga gggctggttt tagaatatca
    16381 gctaagccct tagagcctga gtctgaacca gctgaccctg caccaaggat ttgatggatt
    16441 tcgtcaaaga agagaatgat attgccagcc tccttaacct ctttaaccat gttttgaatg
    16501 ttttcttcaa aggagccacg atactgtgtg ccagcctcaa ggccagaaat atcaattgag
    16561 ataatctctt tatttttgat ggcagctggc acatcaccgt tgacaatagc ctgggctagg
    16621 ccttcgacaa cagcagtttt accaacacca gcgtcaccga caagaacagg gttattcttg
    16681 gttcgtcttg ctagaatttc tgcggtcgct tgaatctcat cgtttcgtcc gatcacagga
    16741 tctaacctgc cttgccgagc ttcttcggtc aggtttgttc cgagcttggt tagaatgccg
    16801 tcttttttaa ggctgctagc ctgtttttct tgtccctcag ctgcagctag cttaccggtt
    16861 ttccggtatt cttgaaattc ctctggtgtc atctcacgtc cattgacaag atagcgacga
    16921 ttttcgctgc ggtagccgcc gatgtttccc attaactgat tgaaaatatc gtccatattt
    16981 tcaaaggggt cttttccata ataggttgcc atatacactt acctcacttg tattatattt
    17041 accagtcatt atgagctact ggtataggta gaaggtgatc ggtgttggct catacagaga
    17101 tcatagagag gtcttatgag agtctattgc tcaggcttat tactcacctt ctaataatat
    17161 tatatccaaa aggtcagtaa aggtcaaaca aaaagtatga ataattaacc tttataatca
    17221 ggtgcttata gcccttgaaa catcagatga ctatgccata agctgctggt gcttttttgc
    17281 tagcaaggct atctgtaaag aagagacttt tgtcaaaaat ggttttactt tttgttctaa
    17341 aggctttcat gatataataa aagaaaagca cagaggtcaa ttatggaaca aacatttttt
    17401 atggtgaagc ctgatggtgt gaaacgtggc ttggttggag agattctacg ccggattgag
    17461 cgtcgtggct ttacctttga taggcttgaa ttgcgacaag caaccccaga attgctagct
    17521 aagcattatg acaccttaat caataagccc ttttatccag agctagaggc ctatatgaca
    17581 agcggacctg ttttaatcgg cattatctcc ggtaatcgtg tggtctcttc ctggcgaacc
    17641 atgatggggg taaccaatcc taaagacgct ttaccgggga ctattcgtgg tgattttgct
    17701 caagcccctg gtgatgatgg cggcattttc aacgtggtgc atggttcgga ttcgagagat
    17761 tcagccaagc gagaaattgc gatctggttt ggacatagct gacattgggc ttgggcctat
    17821 tcttttaaga actgataaag caattgcata aggggttgat aagcccatca tcaatagtag
    17881 ctcagcatta gaagggtaac agccttgatg ttgggctatt tttttgcttg cctagggtct
    17941 gtatgcttgt cctgatgagc aggtagacaa agcagcataa gtttaacaat cctttgcggc
    18001 agtgatcaat tgtagctcta accatagcat cagctatttg aaagccttga aaaagaaagc
    18061 taaggctaac aagctagtct aggtcattta ctacaagcga cttttttcaa ttagctgctc
    18121 aaggcaagta ttgaaaaaag tccatttttc atgtcatttg taataatatg gtatattttt
    18181 aacgaaaagt cgttttagtt gagaaaatat acaaaaaagg ctatgatata gttaataaag
    18241 ttgttatacc ccctgtgtct tgtacactat gacttgtaga gagtttatca aaggaggata
    18301 agatgaacaa acaaagcatg acccattttt ctaagaagct gatgaagtta gcccttttag
    18361 gtttggcatt gccattaagc ttggtgtcgg tggtagatac tccggttctt aaccaatccg
    18421 aaaaagctgt ttatgccaat gattttggat ctggaaatcg agccagtgat tatgtaccgg
    18481 cggctaacgc ttggagcttt gaggcttatc cagattacta cagtatttta ggagctagtc
    18541 atcttaatcc tgctgtcttt ccagagccta gtaagatgtc atacagtcct ttagacgagt
    18601 tgggccgcac acaggtcgca agaggaacaa taacctatca caatatcgtg atgaattaca
    18661 atgttcggca acgctttgct aaaaatcaga acccttcagg ctggattggt aaccctagaa
    18721 atgttcgcta cactattgag tggctagatg gactatccta tcagggagat ttttggaatc
    18781 ggagtcattt gattgcagat agccttggtg gagcagcctt acgtgtcaat gctattactg
    18841 gtacaagaac acaaaatgtt ggcggcagaa atcaaagagg cggtatgcgc tatattgagc
    18901 aaaaggtgca gcagtggatt gagcagcata caagcgcagt tgtttattac gaagcggtgc
    18961 caatttacca ggcaaatgag ctagttccaa gagctgttgt tgtttcagca ttgtcatcag
    19021 acggaggtct tgacgaaaag gtcatggtct ataataccgc caacggctat accattgatt
    19081 atgccactgg cgcattccgc agtaactagg cttttgtact aagctgtagc tgatcaaggt
    19141 ctgactaaga caagctcatc agcaattggt atataaaaag acgtggcaac aacatgtttt
    19201 aaatgagttg tcatgtcttt ttagtgtcgt cagcttttca cattgtctta gaatgatcac
    19261 acctagctag ccgctaaaag cattggtcca aagaaatgtt aagaatagat agaatgcctt
    19321 ttaatcagtg gtatgggact gctagctaat ataatgcctg cagttgagcc aatttctcat
    19381 ctaggctaat aactaacaag ctattgactt atcgtgttca ttagaatgtc agctgttgta
    19441 gttggtagta ttcgaatacg attaagcgat agcaggccat tagcagcact tgctagtcct
    19501 tcatttgttg tgacccctaa tttgtaatgc agatcctcag caatctttaa tgtggtatca
    19561 gtataacgac ctgctggata ggcaattgca atggtatctt ggtgtagctc tctatctagg
    19621 tattctttag aatctttcat ttcagcggtt tgactagcag cgcttgcctg agatagatca
    19681 gggtggttaa ccgtatgatc ttggaaagac atgcctgcct gcttcatttc cttcatctga
    19741 tccaatgtaa gattggccgc attacctgcc tctgtaaagc cagtgataac gttattggtg
    19801 gccttgatgt catacttttt caggattgga aaagcaacgt tgtaaaaatc aaccatgcta
    19861 tcatcaaagg ttagccagac aaccttttca gcaggaagct cgttagctga taagactcgg
    19921 taggcttctt cgggagataa aaagtagtag ccggcctcct tcattgcctt tagctggctt
    19981 tcaaaaagat ctggagcaac gatgagattg gcacttgctg cctcttctgg tgccataacg
    20041 tgaatagcat gatacattaa gataggaagc ttaacagggt tttgctgctt ggtccagctg
    20101 acagctcctt tttgctgctg actatttgta tggctagctt ccttattagt tgcttttttg
    20161 ctaggcttgg gagctggttt tttatcagtt tttgaaaata ggcttatttt ggggattgcc
    20221 tgcgataatt gagagatgct tatctttgaa tggctcttgt aaaggtagac aatagctgat
    20281 aagcctatga tacaggcaag tagtagcatg agattaatca ttttgaagat ttttcttttc
    20341 ttacgccgtt tgtttctgtt gttcatcact tgctccttgt ttattgatta gtctattgta
    20401 acattttttt aagtaagctg tctttcgtta acttaatttt ttgctaacat tctattagtg
    20461 ttatgctttg taaaacaaga cctagatttg ctataataag acagagtatt taagacagtc
    20521 aaaaaaagga ggataggatg tcagttaagg ttgcattatt aggctttggg actgttgcta
    20581 gtggcattcc cttgctatta gaaaacaata gtagcaagat tcgtgcagtg gtaggtgatg
    20641 atttggtgat tgcaaaggtt ctggttagag atgagaccac taagaagcgt ttgttggatc
    20701 aaggctattc ctaccaattt gtgacctcca ttgatgatat tgttgatgat gagagcattg
    20761 atatggtggt cgaattaatg ggtcgtatcg agcctgcaaa gacctttatc tcgcgtgctc
    20821 tatcagccgg aaagcctgtt gtgactgcta ataaggattt gatagccttg tacggaggag
    20881 agctctcgac tttggcagct aagcatcagg tagctttgta ctacgaggct gctgttgctg
    20941 gtggtattcc aatactaaga gctttggctg attcctttgc ctcagataag ctgacgcgtc
    21001 tgctcggtgt gctcaatgga acaactaatt tcatgttaac caagatgatt gatgagggct
    21061 ggacctatga aagggccctg caaaaagcgc aggagctggg ctatgctgaa agtgatccga
    21121 ctaatgatgt gaaagggatc gatgcagctt acaaggttgc tattcttagt cagtttgctt
    21181 ttggaatgac cattgacttt gaggctatta gctattcagg gattgataag gttcgagtag
    21241 aagatgtgac agtagcgcag aagctgggct atgtgatcaa attagttggt ctacttgaag
    21301 agacggcttc tgggcttaac gcagaggtat ccccagtctt tttaccaaag acacacccgt
    21361 tggctgctgt agacggtgtg atgaatgctg tttatatcga gtcaattggg gttgggcagg
    21421 ctatgtttta tggtccaggt gccggtcaaa tgccaacagc tacagctgtt gtggcagata
    21481 tgattcagac tgcctgcacc ttacgtgacc atacagtctc agtctttaat cgttttgcta
    21541 caaaaactag actagctaag tctgaggata ttatgagtcc ctattacttt gctattcaag
    21601 caactaataa gtttggtcag ctactagagc taacaaggct atgtgatgtt tgtggcatta
    21661 gagttgagca gctgttatca gatgagatag atagtgacag gttagacttt gtgatgatta
    21721 ctcatgagat gagcaaaaag gagcttgctt gctttacagc gctactacag gatcatcagg
    21781 atttccgtat gttaagtaca tttaagattt taggagattg acatgaagat acgcgtacct
    21841 gcaacctcgg ctaatttggg acctggattt gactcaatgg ggattgctgt ttcaaaatac
    21901 ctagaagttg acattttaga agaacgtgac caatggttta ttgagcatga tttgggtgat
    21961 attccaaatg atgatagcaa cttacttatc caaacagccc ttaggctagc accaaatatt
    22021 ccagcacatc gtctaaagat gacgtctgat attccattgg cacgtggctt gggatcgtcc
    22081 tcctcggtga ttgtcgctgg tattgaatta gctaatcagc tagggcattt aaacctaaca
    22141 gacgaccgta aattggccat agcaactcgt attgaggggc accctgataa tgtagctcca
    22201 gcgatttttg gtcaattggt aattgcttca cagattggta aggacgtgga ttacatcatt
    22261 gcgccttttc ctgacctttc tttggtttgt tttattcctg attatgagct gaaaacctct
    22321 gattccagag atgtattgcc caagcagcta tcgtataagc aggcagtggc tgcttcctca
    22381 gttgctaatc ttgctatagc tgcgctattg accggtaatt tgaaaaaggc cggtcgggcg
    22441 attgaaaatg accaattcca cgaaatctac cggcaaagat tagtcagaga gttccagccg
    22501 attaagcgag ctgcagcagc taatggtgct tatgcaacct acttatccgg tgcagggcct
    22561 gctattatgg ttatgtgtcc caataagaaa aaaatggcga tttatgaggc catcgagcag
    22621 ctaggtctaa ttggtcagtt ggtgtctcta gagctggatc gtcaggggct gtgtcttgtc
    22681 tagactggca aggtactggt atgcttgcct agtaggctta ttgttgatat cagatggact
    22741 taaagcttag tcattcaaat acatcaaaaa agtgaggctt gatcgtttta tcggctttca
    22801 cttttttctt gatatgttat actagagtag actttgtgag gtgtgtgatg aattatcaag
    22861 aaacattaga ctggattcat ggtcaggaaa gatttgggat caagccaggt gtaaaacgca
    22921 tgcgttgggt gcttgagcag ctaggtaatc ctcaagatag gattagagga atccatgtgg
    22981 tcggcacaaa tggtaaggga tcgacggtca atgacctaca gcatattttt actagagcag
    23041 gctatgaggt tggaaccttt acctcgcctt atatcatgga ttttaaggaa cgtatctgtc
    23101 tcaatggtga gatgatctca gagactgacc ttgttaaggc tgctaattgt attcgtccac
    23161 taacggatcg ccttatcagt gagacaagtt tgggtcctgc aacagtcttt gagctgatca
    23221 ctctgatcat gtttctttat tttggtgaga gtcacccggt tgatattgct attatcgagg
    23281 caggattagg ggggctttat gactccacta atgtgtttca ggcgatggct gtggtttgcc
    23341 cgtctattgg tcttgatcat caagctattt taggtgatac ctatgctgac attgcctatc
    23401 aaaaagccgg tgtgctaaag ggtggtgaag accttatttt tgccattgat aacaaagagg
    23461 ccagacaggt ttttctaaaa aaagcagagc agcttggcgt gcctatttgg gaatggcgtc
    23521 gacagttcaa catgctacag ggtgaaggtg gttatcaatt taacagtcag cttggtcagc
    23581 tgtctcatct agtgcttgca atgcctggtc agcatcaggt agccaatgca ggcctagcca
    23641 ctatgacaag cttgatatta caggatcggt acccaaaggt aactgagtct gttattagag
    23701 aggctctggc aagcagcttt tggttgggac gaacagaatt gttggcaccc aacctgatga
    23761 ttgatggtgc tcataataat gaaagcattg ccgccctgat tgatgtgata tcatcagact
    23821 atcaggataa gcagattcat attctatttg gtgccattga taccaagcct gtctcagata
    23881 tgctgcagag tctggagcgt cttggagatg tgcaagtaac aagctttcac tatcccaatg
    23941 cctatccttt ggaggcttat ccagataggc taacaaaagt agcagatttt agagcatttt
    24001 tagaccggct tgagcaagca gctgctgatg attttttcct gattacaggc tctctttact
    24061 tcatctcaga ggtcaggcag tattggaaaa aggtattaag caagtaatgc tttctcacat
    24121 caactcatca aacaagatta atcaactaaa aaggggaaaa ccattgccaa tcaatcaaaa
    24181 aaaagcagaa gccgctatct atcaattatt agaagctatc ggtgaggatc caaaccgaga
    24241 agggctacga gataccccaa agcgtgttgc caagatgtat ctagaaatgc tctcagggct
    24301 ggaacaggac gctaaggatg aatttacagc tgtttttaca gagcatcacg acgatttggt
    24361 gattgttaag gatattagct tttattccat gtgtgagcac catctggtgc cattttatgg
    24421 taaggcgcat attgcttatt tgcctagtga tgggcgtgtg acaggcttga gtaagctggc
    24481 aagggcagtt gaggtgacga gcaaaagacc tcagctgcag gagcgtttga cagctcagat
    24541 tgctaatgct cttgttgatg ccttgcagcc caaaggggtt tttgttatgg tagaagcaga
    24601 gcatatgtgc atgaccatgc gaggtgtcaa aaagccaggc agtaagacca ttacgacaac
    24661 tgctagaggg atttacaagg atagtagaga cgacaggcgt gaggttatgc aattaatcat
    24721 ggagggctag ggtatttatg actattggac attattcagc cgctggtgag gcagctatta
    24781 tggggatttt aaatgtgact ccggattcgt tttcagatgg tggctcctat actagtgtta
    24841 atcaggcctt ggcacaggcc gaaaaaatgc tgtcagaagg agcgactgtc attgatattg
    24901 gaggcgagtc aacacgaccg ggctgccaat ttgtgccggc agaagaagag attgcacgcg
    24961 ttgttccaat cataaaggcc attaaaaaac ggtatgatgt ccttattagc attgatacct
    25021 acaagacaga aactgctaga gcggcccttg aagcaggagc agatatgctc aatgatgtct
    25081 gggcaggact atatgacggt caaatgctaa gtctagccgc cgaatacgac gttcccatta
    25141 tattaatgca taatcaaacc aaagaggctt atgctgatgt tacaaaagag gtttgcagct
    25201 ttttacaggc tagagcagct gcagccctca aagcaggtgt caaaaaagaa catatctggc
    25261 ttgatccagg atttggcttt gctaaaaatg ttgagcaaaa tatagcctta ttaaaagggc
    25321 taaatgaggt ttgccagttg ggctatcctg ttctttttgg gatttccaga aagcgtgttg
    25381 tagacgccct acttggtggc ggcactaaag ccaaggatcg tgacggggct actgccgccc
    25441 tatcagccta cgctattaat aaggggtgtc aaatggtgcg cgtgcataat gtcggtgcta
    25501 acagggatat tgtctctgta ttgagtcaat taaggtgaga aatgatggat aaaatcagat
    25561 tagaggcttg tcgcttttat ggttatcatg gtgcctttaa ggaggagcag gtcttaggtc
    25621 aaatttttgt agtggattta gaattatcag ttgacttgat ggctgcctct ctttcagact
    25681 gcctagagga tactgttcat tatggtttag tttttgaaac agtccgtcaa attgttgagg
    25741 aaaagacctt tacgcttatc gaacgtttgg ctggtgccat ttgtcaagag ctatttgccc
    25801 agtttttgcc tattaaagcg attaaaatcg ctattaaaaa agaaaatcca ccgattgcag
    25861 gccattatca agctgtcggt attgaattgg agagaaagag atgacacttg tttatttagg
    25921 cttgggaact aatatgggag atagggcagg ctacctacag gcagcagtta atgccctatc
    25981 taagctgcca gagactgagt tactgagaca atcctctatc tatcaaacag cagcctgggg
    26041 aaaaacagat caaaatgcct ttttgaatat ggcttgccag ctagatacta ggctgacatc
    26101 agaagctctt ttggcagcta cgcaggctat cgagcaggct ctgggacgag ttcgtcatga
    26161 aaaatggggc ccaaggacaa ttgatattga cctcttgctg tttggtgatg agccgtatca
    26221 atcagagacc ttggttattc ctcaccctta catgacacaa agagcctttg ttttgattcc
    26281 tttattagag attgcacccg atgtgacctt acctggtagc cagaaaagcc tgaggtctta
    26341 ccttgatgct ttagagcaat cagatgtagc cttgtggtca catgagtatt caaataagtt
    26401 ttcttaaact gtcgttattt ttactaaaat ttgatataat agtgctactc tttgctgatt
    26461 ttttgtctta tattaagaaa tgattgaaga aagaagaaga ttatgatagc tgaacttgaa
    26521 ggcattgata ttcgagagaa tgaagcctta aaacattaca cctataccca agtaggcggt
    26581 ccagcagatt tcttggcttt tcctagaaat cattacgaac tatcccgtat tgttgattat
    26641 gccaatcata atcatattcc ttggatggtc cttggaaatg ccagtaatct cattgttcga
    26701 gacggtggta ttcgtggctt tgttatcatg tttgataagc tcaacgccgt ccgccttaat
    26761 ggttatacct tggaggcaga ggcaggcgct aacctcattg aaacaacaaa agttgccaaa
    26821 tttcatagct taacaggctt tgaatttgct tgtggcattc ctggaagcat agggggtgct
    26881 gtttttatga atgcaggtgc ttatggtgga gagattgctc atattttttt gtcggccaag
    26941 gtcttgacac cagaagggaa aataaaaaag atctcagcca gagagatggc ctttggctat
    27001 cgtcactctg tcattcaaga aactggtgat attgtgattt cagccaagtt tgctttaaaa
    27061 ccgggtaatc atgacagtat ttgtcaggag atgaatcgcc tcaaccacct tcgaaagctc
    27121 aagcagccct tagaatttcc ctcttgtggg tccgttttta agcgtcctcc tgggcatttt
    27181 gcagggcaat tgattatgga cgctaaccta aaagggcatc gtgttggcgg tgttgaggtc
    27241 tctaaaaagc atgcaggctt tatgattaat gttgctgatg gctctgccaa ggattatgag
    27301 gacttaattg ctcatgtcat taggacagtt gagcaggcat ctggcgttag gcttgagccg
    27361 gaggttcgta ttattggtga aagcctttaa tgattgtgtt atcaaaaaag aaaaattgtg
    27421 gaggatttat gacaattgac taagccaatt atcacatttg acaatgtctc aaagacattt
    27481 gaggacagcg ggacacaggt cctaaagaac attaattttg agcttgagga gggaaaattt
    27541 tacaccctgc ttggtgcctc aggatctggg aaatcaacca ttttaaatat tatggctggg
    27601 ctgcttgatg cgaccagtgg tgatatttat ttagatggtg agcgtatcaa tgatttgccg
    27661 accaataagc gtgatattca cactgttttt cagaattatg ctttgtttcc tcatatgacg
    27721 gtttttgaga acgttgcctt tgctttaaag ctgaaaaagg ttgacaaaca ggagatagca
    27781 agacgtgtca aggaaacctt aaaaatggtt cagctggagg gctacgaaaa gcgatccatt
    27841 caaaagcttt ccggtggtca gcgtcagcgt gtagcgattg ctcgtgcgat tatcaatcag
    27901 cctcgtcttg tcctattaga tgagccactt tctgcccttg atttgaaatt gagaacagaa
    27961 atgcagtatg agctgcgtga gctgcagcag cgactgggca ttacctttgt ttttgttacc
    28021 catgatcagg aagaagcact agcgatgagt gattggattt ttgtcatgaa tgatggtgaa
    28081 attgtgcaat caggcacacc tgtagatatt tacgatgagc cgattaatca ttttgtagct
    28141 agctttattg gtgaatcaaa catcatcaat ggtacgatga ttaaagacta tctggtttcc
    28201 tttaacggga aagaatttga gtcagttgat ggtggtatgc gacccaatga gccagttgag
    28261 gtggttattc gaccggagga tttacaaatc accctgccag aggaaggaaa gcttcaggta
    28321 aaggtagata cacagctctt tcgtggtgtt cactatgaaa tcattgccta tgatgattta
    28381 ggcaacgaat ggatgattca ctcaacccgc aaggccattg aaggagaagt gattggttta
    28441 gatttcacac cagaggatat tcatattatg cgcctcaatg aaacagaaga agaatttgat
    28501 gctcgtatcg aagaatacgt tgaaatcgat gagcatgcgg atggcttaat caatgctatt
    28561 gaggaggagc gcaatgaaga aaacctctag cctctttgca gttccctatt ttttatggat
    28621 tgtcctcttt gttatggcac cggttgccct tttgctttat caatcctttt ttgacatcga
    28681 aggacgattg acactagcca attacgagac tttttttagc tcatggactt acctgagaat
    28741 gggcttaaac tctatcttat atgctggtat cgttaccttg gtgacctttt tgatttcata
    28801 tcccacagct ttattgttaa cgcgtttaaa gcacaagcag ctgtggttaa tgcttattat
    28861 tttaccaacc tgggtcaatc tgctcctcaa ggcttatgct tttatgggga tttttgggca
    28921 gcagggtggt atcaatagct ttttaacctt tatgggctta ggaccacagc aaattctgtt
    28981 tactgatttt tcgtttattt ttgtggcctc ttatattgag ctgcccttta tgattttgcc
    29041 tatttttaat gctttagatg atattgatga taatattatc aatgccagta aggacctggg
    29101 tgccaatgac taccagacct tttcaagggt tatctttcct ttgtcgctaa acggtgttag
    29161 agcaggggtt cagtctgttt ttattcccag cttgagtctc tttatgctta cgcgtctcat
    29221 cggtggaaat cgtgtgatta cgctggggac agctattgaa cagcatttcc taacaacaga
    29281 aaactggggc atgggctcaa ccataggtgt tgtcctaatt atcgcgatga ttgtgattat
    29341 gtggctaaca aaggagaaaa gtaaatgaaa aaatttgcca atctttactt agcgtgtgtt
    29401 tttattttgc tctatattcc aatcttttac ttgattgttt attcttttaa caagggtgga
    29461 gacatgaatg gcttttctgg cttgacgcta gagcattata agaccatgtt tgatgatagt
    29521 cgcttgatgg cgattttatt gcagaccttt gtgttagcct ttacaagtgc cttgcttgca
    29581 accattatcg ggacctttgg ggcgattttt attcatcaga gtaaaaagaa gtaccaaaat
    29641 gcgatactgt ctgcaaataa tgtgttgatg gtttcccctg atgtgatgat aggtgcctct
    29701 ttcttgattc tctttacgtc cttgaaattt caattaggaa tcctctcggt tttgatgagt
    29761 catattgctt tttccattcc gattgtggtc ttaatggtgc ttcctcggtt gaaggaaatg
    29821 aatcaagata tgattaatgc agcttatgat ctaggagcaa atcactttca aatgctaaag
    29881 gaggttatgc ttccttatct gacaccgggc attatcgcag gctactttat ggcctttact
    29941 tattccttag atgattttgc ggtgaccttt tttctaacag gaaatggctt tacaaccctg
    30001 tctgttgaga tctattcgcg tgctcgaagg ggtatttcat tagatatcaa tgccttatca
    30061 acgattgtct ttttgttctc aattctatta gtcattggct attattacat ttcacaggac
    30121 aaggaggaaa agcatgcgta agctatactc ttttttagcg ggaattatcg gggttatctt
    30181 gctgcttgcg accctgtcct ttattttgca gaaaaaaacg agctctgcta gtcaatctga
    30241 taagctggtg atttataact ggggtgatta cattgatccc gctttgctga aaaaattcac
    30301 taaggaaacc ggtatcgagg ttcagtatga gacctttgat tccaatgaag ccatgtacac
    30361 caagatcaaa cagggtggaa cgacctatga cattgctgtt ccgagtgatt acacgattga
    30421 caagatgatt aaggaaaagc ttcttgttaa gctagataag tccaagcttg ttggtctaga
    30481 taacattggt caggagtttt taggaaaaag ctttgatccg cacaatgatt attccattcc
    30541 ttatttttgg ggaacggtag gcattgtcta taatgaccag ctggtggata aggctcctat
    30601 gcattgggag gatttatggc ggccagaata ccaaaatagt atcatgctag ttgatggtgc
    30661 tcgtgagatt ttaggtgttg gattgaccac atttggctat agcgttaact caaagcacct
    30721 aaagcagctt gaagcagctg aaaaaaaact acaggcctta acccctaatg taaaagcaat
    30781 cgtcgctgac gagatgaagg ggtatatgat tcagggtgac gctgctattg gtgttacctt
    30841 ctcaggagag gctagcgaaa tgctggacaa taacgaccat ctacactatg ttgtaccatc
    30901 agagggctca aacctttggt ttgataatct ggtgcttccc aaaacaatga agcatgaaaa
    30961 tgaagcctat gcctttatca actttatcat gaagccggaa aatgcagcac aaaatgctga
    31021 atatatcggc tatgccactc ccaatacaaa agcgaaggct ttattgccag atgatattaa
    31081 aaatgaccca gccttttacc caactgacga gaccgtaaag aaattagagg tttatgataa
    31141 tttaggctct aaatggcttg gtatttacaa cgacctttac ctacaattta agatgtatcg
    31201 aaaataggtc atgcaagatt gaaggagcta ttcattggaa agcttcttca gtctttttta
    31261 gcttggtctg gtctcaataa tctcatgaga ttaaaaagaa ctagaatctt gctttcgtct
    31321 ttgatacaat agtagtggtt tattaaaatg aaagagatga caaaatggaa aatcataaaa
    31381 acgagtttac cttttccaaa cattcaatca tagcctacgt ttggcgtggc attttagtcg
    31441 ggataattgc tggagctatt gtcagtttgt ttcgcttatt gattgagatg gttagtgagg
    31501 ctgttgttgg ctattatcac caagctcaca gcaatcgcat gctccttgtt ccgatagcag
    31561 gctttagctt attagctgtt tttttagttg gtcttttggt caagtctgac gccaacatta
    31621 aaggctctgg tattccacac gtcgaagggg agctaaaggg cttgatgtca cccaattggt
    31681 ggagtgtgct ttggaaaaaa taccttggtg gaacaattgc catttctatg ggcttaatgc
    31741 ttggaagaga aggcccttct atacaattag gggctatgtc agctaaaggc ttagctaagt
    31801 acctgaaatc tagtcgtcta gaaaaacgtg tcttgatcgc tagtggagca gctgctggct
    31861 tatcagctgc ttttaatgcg cctattgcag gactgctttt tgttgttgag gagatttacc
    31921 accatttttc aagattagtg tggatcactg ccttggttgc aagccttgtt gcgaacttta
    31981 tttcgttgaa tatttttggc cttagacctg ttttggccat gcctaaggcc atgccctttc
    32041 ttgccttaca tcaatattgg ctgctcttaa tcttaggcct tgtgcttggc tgtctgggct
    32101 ttctttatga agaggtcatt ttacattttc atagggttta tgattttctt ggaaagagct
    32161 tgcgcctagc gccgcatttt catgggctga ttgttgttgc tattatcctg ctgattggct
    32221 attatttgcc acagctattg ggcggaggtc atggtttgat tatgtccttg tcagagcaaa
    32281 agctaccact gttgactgtt cttgcttact tctttattcg atttttaggg agtatgttta
    32341 gctatggcag tggcctgcct ggaggaattt ttttgcctat tctaacctta ggtgccttgt
    32401 ccggaactat ttttggattg attcttcagc aaataggact gttagatcgc cagatgattc
    32461 ctctcttttt agtattggga atggcaggct actttgctgc tgtatcaaag gcacccttga
    32521 caggaatgat cttagtgact gaaatggtag gggatctgaa gcccttaatg gccattgctg
    32581 ttgtgacctt cgtggcctac ttggtgatgg atttgttaaa tggtcagcct atctatgaag
    32641 caatgctaga gaaaatggct atcaaacacc caacagatct agtggagccg accctgatcg
    32701 aattacctgt aagtgagaaa attgcaggca gatatgtccg agacctgaag ctacctaaaa
    32761 acgttttaat tacaacgcag ctccaccata agaaatcaca ggtcgtctca ggtgatacgc
    32821 tattgatttc aggtgctacg atctttttgg tggtcaatga agctgataca ggctttgttc
    32881 gagaggtctt gatgtagagc aaggtcggtt aagcagtcag cagtagctgt gctaccgatc
    32941 aaagaagcag atcagtgctt tttctcatct gatgaaaggt attgatttgc tttttttgtg
    33001 ttattaaacc tttgttagca agagccatag ccttagcagt cgtatctgat gaatacctgc
    33061 tgtctttttg ttatacttaa gtatcaatca aaggagcttt atatgctaga agttatttca
    33121 aaagagctgc gccattacca aaagaataag cttgccgcct atcaaaaaaa gaaccaaggc
    33181 atagaagctg gtggaattgt ttttgctggc gattcgttaa tcgaattttt cccgttgaaa
    33241 aaatatttca aacaggtctc aaccatttat aatcgcggaa ttgcagggat agacagtcag
    33301 tggttgctag agcatattga cagtcatgtg aatgatctgg agcccagtca tgtgtttatc
    33361 ctgattggct gtaatgatat tgggcttggc tttgatcaat cgcatatcgt atcgaccatt
    33421 gttgatctta ttagtcgtat tcgcagtcag tctatttata ctaggattag ccttctgtcc
    33481 ttattgccgg tttctgaaaa tcccgcctat caggcgactg tcaagctaag gacaaatagg
    33541 gctattgatg agattaatca agcattagca atgataccag cgattgaatt tattgatctt
    33601 aacgcctgct taaaggacga gactggtggc ttagcagctg cttatacggt agatggcatt
    33661 catcttaatg cccttggcta tgaacactta gctcaagcta ttagtcccta tctatgaaag
    33721 gtaaaggctg gagctgctaa tttgtaaggg atctttaaaa aacaagcact gatgaatcat
    33781 cattgaaacc cttcagagtg ccgataggct gcacaatcaa agaagcatta ggtttgtcta
    33841 tgacgccctt gtgttaagct ggcttttagg tttatactgc gagaaaatca gtcattgggc
    33901 tgggagtctc aaagcttagc tgtggtaatt aaatgcgagc tcctgctagc ttgtgctgat
    33961 caagcagtat agcaaggagg gactgaactt ttagtctcag ataatattag actttttatc
    34021 ctatattaaa cgatttagtg tataataaac aggaaggagt taaaatgaaa tttgaaaaaa
    34081 aacaagtctt ttatgttgtg cttgcctttg tgctttgtta tgctattcaa gctaattggg
    34141 ataatggggc taatattgtc acaaccgttt ataagacaag cctgcccttt ctttatggag
    34201 cagcagtcgc ctatattgtt aatattgtca tgagtgccta tgaaagagct tatacttata
    34261 ccctaaaacc ctttcctttt gccatgaagg ctagaagagg gctctgtatg cttttggcat
    34321 attttacctt tatcagcttg atcgtatgga ttatttctat tgtaatccct gatttgattg
    34381 caagcattag ctcgttaacg caatttgata caagagctat caaggaggtc atcagtgatt
    34441 taggtcacaa taagctgatt gcacgtgcca ttaattacat tggtggagat gctaagctga
    34501 cagaaacaat taccaattat agccagcagc tgctcaagca atttataggt gttctaaccg
    34561 gtattttgac atcggttaca gcagttgcct cagccattat caatgtggtt atcagctttg
    34621 tcttttccct gtatgtgctt gctagcaagg aagagctttg tcagcaggca actaccttaa
    34681 ttgacaccta tactggtaaa tacgcaaagg ccattcatta tttagtgggt ttgctgcata
    34741 gtcgttttcg tggcttcttt gtgagtcaga cgcttgaagc aatgatttta ggctccttga
    34801 ctgccattgg catgtttatc ctgcaattac cctttgcagg aactattgga gtcttggttg
    34861 cttttactgc cttgatccct gttgttggtg cttcaatcgg tgctgcgata ggctttgttt
    34921 tgattatgac tcagtcaatg tcgcaggcag tcgtctttat tgtctttctt gttatactac
    34981 agcaaatcga ggggaatttt atttatccca gagtggttgg tgggtctatc gggttaccag
    35041 ctatgtgggt cttaatggca atcaccattg gtgctgctct caaaggcatt gttggtatga
    35101 tcgttgcagt gccattagcg gcaacgcttt atcaagtggt aaaggatcac attcataaaa
    35161 agcaggcctt acaaaatcgt cagtccagct aattaacagc atcagatcaa ggaaaacgtc
    35221 tattacaaga ccgatttctt ggtcttttat gctgtctgat tgactgcgta tggccttatt
    35281 tttatgctgt ggtaatgaaa aaagccgtct tatttatcga atatcattag tggaggtaat
    35341 aagatgtatt ccatcaaaac tgatcataaa ttaatgccta gagagcgttt gattcgactg
    35401 ggtccagaaa agctaagcaa tcaagagcaa ctagcgatcc tacttaggac aggtaacaag
    35461 gaaaagcatg tcttagagtt gtctgcttat ttattgtcaa gcttagatag tctagctgac
    35521 ttgaagaaat tttctttaca agaactacag cgcttatccg ggataggaaa ggtcaaggct
    35581 attgagatta aggccatgct ggagctggca gaccgtattc agatagcggg acaagcagta
    35641 gcagatcctg tcttatctag tgctcaggtg gctgaaaaga tgatgattga attaggagac
    35701 aagcagcagg agcatttagt cgctatttat ctcgatagtc aaaataaaat cattgaagaa
    35761 aagacgatat ttataggaac cgtcagaaaa tcaattgcag agcctagaga aattctttat
    35821 tatgcgtgta aaaatatggc gactagcctt attgttgttc acaatcatcc ctcaggcctg
    35881 accaagccaa gcgcaaatga ctatcacttc acagaaaaaa taaaacgatc atgtgattat
    35941 ttaggactta tctgcctaga tcacattatc gttagtaagt atgactacta tagctttcgg
    36001 gaaaaatcag atttattttg agttagaaac tatggataaa ccaatcaaag agccttaggt
    36061 cttcttctct aatagcctga agcagctctg ggtgccactg gacaccgaga aagggaatat
    36121 caggattgca ggagataaca gcctcgatgg tgccatcgtt aggatccctt gcaatcactc
    36181 ttaagtcctc tgcgacctgc tttaggctct ggtggtgaaa tgaattaatc agcgctcttg
    36241 gaccatagat agggtacaaa ggtgaagtct tttcgatcac tatctcctgt gataaacagt
    36301 cagaggcagt cttttgccaa tggccctcaa tgtgctggtt tagactgcca cctagagcaa
    36361 catttattaa ctgcataccg cgacaaatcc ctaaaattgg ttttttctgc gctagggctt
    36421 ctttaatgat ggctagctca aagatgtcac gctggggtga aaaatcacca tcaagtgcag
    36481 ctcttttttc atgataatat ttaggatcaa catgctgacc accaataaga atgattttat
    36541 caaccattgc gacataggat ttggcagccg cctcatcccc aatcggaaga agtaagggta
    36601 ggccaccaga tcttgtcaca gcctcgatga agcttgttgg agcataggag caaggcaggt
    36661 tatctagagc cttggtcccc ctttggttag cagttatccc aataattgtt ttagacacga
    36721 ccttctccat taatcaagat gattttggtt cataaagtat agcaaggttt gcaactcgct
    36781 ggtcaaatca acagattgga cgatcacacc ttttggaacc tgtaagtgaa gtggagcaaa
    36841 gcttaaaata ccgcgaatgc cagcttcaat cagttgatct gcaacctctt gagcatagat
    36901 gcttgggact gttagaatag ccgtttcaat gcctgaatta tccaggtgct ccttaatggt
    36961 agaaatgcca taaataggaa tatcatcagg cgttttggtg ccgaccatag gattatcatc
    37021 agtgtcaaat cccataacaa tctgcatttt gtttcgatcg tggaagcggt agtgaagaag
    37081 tgcacgacca atattgccgc agccaactaa aatcacatgc gttgttgagt gatcatttag
    37141 caaatctgca aaaaaattca ttaattttgt gacatcatag ccaaatccac gtcggcctaa
    37201 ttcaccaaag taagaaaaat cacgtcgaac agttgcagaa tcaattccca tagcatcagc
    37261 aatctgtttt gagcttgcct tttcaacctg atcagcataa aagcgtttaa aaatacgata
    37321 atagagtgat aagcgttttg cagtcgcttt tggaatagat ttatcaataa ccacttttgt
    37381 agctccttct attgttattt taatgttatc tatcaccatt gtagcagata gattgtgaaa
    37441 tatgcaacta tttgaccatt ctttttgtgt ttttcgttat aaaatgactt gacagcacaa
    37501 gcattggtat ttttcaaacc cagtcacctc gagtataaaa aagcagacaa tgaagcactt
    37561 gccctttagg tcagctgcga tggctgggct tgtcttgtta aaggcaaatg tactgtcatt
    37621 gtctgatatt tctctgagat tagaagagct cttgtgtgct tagcattctt ttttaatgaa
    37681 aatatcacgc tcaacaaggc tatccattaa aaagtaaaac ttgtcctgta gtatgctatg
    37741 ctcttcagat ttaaaaatgt tcaccagtct tagaccggat tggtctgtta tagctagctt
    37801 aaagccatct aaatctttat taatcgtaat ttttaaaggg aagccctcac ccgaattagg
    37861 gactttttcc agtagtcgtg ttaactgata gtgaccaatc ttggtctgac taaaggttgt
    37921 gtctcttagg gtgtattttt taatctttgg gctaatcctg tagctgtatt tgcagtcttt
    37981 aagggcaatt tctttttcaa atgccatatg atcctcctaa aatatttttg agctgggttg
    38041 ctagtgcgat aacgtctttt tgagtatttt gctctgaaaa gctaactcga atagcttctg
    38101 tgagacgatg ggactgcttg ccgaaataag ctgccaaaac gtgacttggc tcaacagcac
    38161 cagctgtaca agcagagcct gacgacacag caaagcctgc taaatcaagc tgagtcagta
    38221 atacatgatt ttggtaacca ggaaagccga tattaatgat atagggaaga tgacactcat
    38281 tatgattgag ctgataagaa ataccttcta attcactaag caagagctgt gatagctctt
    38341 tagcatgctg gtaatgctgt ggcagccttg agacagcctc atctaatgct tgggtcatgc
    38401 cgacgatatt aatcaggctt tcagtgccgg ctctttgttt gttttcttga ttgccgccat
    38461 gtaagagggg ggccaacttt aagcctttat tgtataaaaa accagtcccc tttggtccat
    38521 gaaacttatg ggcagaggca gagagcaaat caatccccaa atctgccggc tgtattggga
    38581 ccttgccaat agcttggaca gcatcaacat gaaagacagc ctgatgctgc tttagcatgc
    38641 taccaacagc ctgaataggc agcaaatctc ccgtttcgtt gttagcaaac atcatgctga
    38701 ctaagattgt atcctctctt aaggcagctt ggagctgatt tagatcaatg attccatttt
    38761 tagcctcaag gtaggtcacc tcaaagccaa atcgttcttc cagataggcc attgtgctta
    38821 acacggaatg atgctcaata gcagttgtaa tcaagtgttt gcctttttcc tgatgagcta
    38881 aggcatagcc cttgatagca gtattgttac tttcagtacc tcctgaggta aagataatgt
    38941 ggttttctgc agctcctagg cagttggcaa tagcttttcg gcactctctt aattgtttgt
    39001 ttgcctgccg cccataagca tgaatactag atgggttacc aaaatcatca gccatagctt
    39061 cagtcatcgc cttgatagca gcctgactaa gcgatgttgt agcagcatta tcaaaataaa
    39121 tcatgattag ttagtgcttt caggtttgta agaaaacagt ggacttagtg gttttctttc
    39181 gtgaatgcga atgatagcct ctgcaattaa atcactggca ctaagatagg ttactgtttt
    39241 agggatacga tttttagtct tgacagagtc cgtgacaatg atctctttga ttggagcagt
    39301 ctctaaaata tcagctgcac ctcctgcaaa aatcccatga ctagccactg cataaatgtc
    39361 agttgcgcct gcacattcta ggatcttagc tgcctctgca aaggtttttc ctgtgttgag
    39421 aatgtcatca atcaagatag ccttcttgcc agcaacatca ccaatcacat agccttcttc
    39481 gcgctcagca tcgtcttgtg cataatcgat aatggcaatt ggagagttaa gatactctgc
    39541 taagcttcta gcacgcttga taccagaatt tttagggctg acaataaccg tatcaggtcc
    39601 tgagaggccc agtggataat agtgctttgc aaaaagaggc actgtaaata aattatcaac
    39661 tggaatgtca aaaaagcctt ggacctgaac cgcatgcaaa tcaagggtta caacgcgatc
    39721 aatccctgct ttggtcagca tgtttgcgac cagctttgct gtaataggct cgcgagactt
    39781 tgcaacacga tcctgacgcg aataaccaaa atatggcaaa acaatattga ctgtattagc
    39841 acttgcacgc ttacaagcat caatcatgat gagcagctcc cataggttat cgttgacagg
    39901 aaagcttgtt gattgaatga tataaatatc atcaccacga actgtttctt caatgttaat
    39961 catgatctca ccatcagaaa attgacgaga tgagaccttt ccaagcggaa taccagcagc
    40021 cttagaaatt ttttcagcga ttgcgagatt tgaagtgagt gagaacagct tgatttgctt
    40081 gtcagcatat cgttcagtca tgataaaatt agctccttac attacattaa cgatagaata
    40141 acaggttaac agttattcaa gattacaaat agacagtact attttaacaa aaaaacagaa
    40201 aaatttcagt ctttctgttg attttctgtc ctctcctagg attttttaag ggtcttgcta
    40261 aagcgagcga ccttgctttt ggaatattta aaggtgatct gatgctgggc taaaaagtgg
    40321 tcaaaatcaa cctttcctct tacaggatca gtcacctcta gctcaagctc atagtctttg
    40381 ataccagcat attgattata atccagcgct agcttgccaa taggagtatc tgcctctcga
    40441 cgaatggtag tcaggtttcc gaaggttttt atagcagata ggtcaacgtc aagagtgctg
    40501 ataatatcaa ggatagctga ttttggtagc tgtcctgtct gaatgatagc ttttgcttgg
    40561 gtgtcatcaa gctctaaatt gtactcgcga ttaccaacct tttcagggac ttttaaggtt
    40621 aattcagcag gagcagcaac aaaggtgcga atgcgaagtg acattttatg agccttgaga
    40681 tcaaaatgat cagtatcaat gtaataattt gtctgggtaa ctggtgggac atgagtcatt
    40741 tgagagagga ggcgattata ttcgtccttt gtcagtaagg tcttgtattc gatttctagg
    40801 ttagtcatgc gaacgttcct tttaactata ttttatgcta taataaattg ttatcttaat
    40861 tttatattaa tatccgaggt ttgacaagaa aggagagaaa ggatggcttt agattgggaa
    40921 gaatttttgg atccttatat acaaacggtt ggcgaattga aaattaagct gcgcggtatc
    40981 cgaaagcagt ttcgcaagca aaaccgttat tctcctattg agtttgtgac tggacgtgtc
    41041 aagtcggttg agagcatcaa ggaaaaaatg gccttgcgtg gtgtcttgga agaaaatatc
    41101 gctcaagata ttcaagacat cgctgggctt aggattatgg tgcagtttgt ggacgatatt
    41161 gaggacgttt tgtccttgct tagacaaaga caggacatga caattgttta tgagcgagac
    41221 tacattagaa acatgaaatc tagtggttat cgctcgtatc atgttgtcgt tgagtatcct
    41281 gttgatacca ttgagggtca aaaaaaagta ttagcagaaa ttcaaatccg tactttagca
    41341 atgaattttt gggcaaccat tgagcattcc ttgaactaca agtacggtgg tgattttcca
    41401 gaagaaataa aaaaacgatt agaggttaca gcaaaaattg ctttggagct tgatgaagaa
    41461 atgcgaaaaa ttcgtgaaga cattcgtgaa gcacaattgt tatttgatcc tgtaacacgt
    41521 catttgagtg atggtgtagg aaatagtgat gacacagatg aattatacag ataaagtaaa
    41581 gcgcgttgct atcattgcaa acggcaaata tcagagtaag cgccttgcct caaagctttt
    41641 tggcgtcttt aaggacgatc cgagttttta cctatccaaa aaaaatccgg atattgtgat
    41701 ttcaattggc ggagatggca tgcttctatc agcctttcat atgtacgaaa aagaattaga
    41761 cagggtgcga tttgtaggca ttcacactgg acaccttggt ttttacactg attatcgtga
    41821 ttttgaggtt gatcaattga tagccaatct tagaagagac accggtgagc aaatttctta
    41881 ccctatttta aaggtagtta ttacgcttga tgacggtcgc ctgtttaagg ctagggctct
    41941 caatgaagca actattaagc gtatcgagaa aacgatggtt gcagatatta tcattaacaa
    42001 tgtcaagttt gaaagctttc gtggtgatgg catctctgta tccacaccaa ctggaagcac
    42061 agcctataac aaatccttag gtggagctgt attgcaccca acgattgagg cccttcagct
    42121 aacagaaatc tcgagcctga acaatcgtgt atttagaacc ttggggtcct cagtgattat
    42181 tcctaaaaaa gataaaattg agcttgttcc aaaaagacta ggcgtttata ctgtctctgt
    42241 tgacaataaa acctaccact taaaaaatgt ggttaaggtg gaatatttta tcggcaatga
    42301 aaagattcat tttgtgtcct cacctagcca caccagcttt tgggaaaggg ttaaggacgc
    42361 ttttattggg gatagtgaat catgaggttt gaatttgttg caactaaaaa aacaaaggta
    42421 aagacccttt taaaagagca cgatgtgtca aagggattgc tcgctaagat taaatacaag
    42481 ggtggcaata tatgggtaaa tggcgttgcg caaaatgcca tttatttatt ggatattggt
    42541 gatgtggtgg ctattgatat tccaaatgag gagtcctttg agcaattgac agcgatttcg
    42601 catgaccttg atattgtgta tgaggacgaa cattttctca ttctcaacaa gcctgctggc
    42661 tacgctagca ttccaagtgc tatccattct aatactatag ctaattttat caaggcttat
    42721 tatatcaagc aggactatcc caataaacag gttcatattg tgacgcgctt agatcgggat
    42781 accagtggct taatgctctt tgccaagcat ggctatgccc atgccagatt agataagcag
    42841 ctacagcaaa gagctatcaa taaacgctat tatgctcttg tttgtggtca ggagaggctt
    42901 ccagatcaag gtgagattat agctcctatt ggccgtacgg acgacagcat tatcacaaga
    42961 actgtcacgc caaagggaaa gtatgctaag acaagctaca aggtcattgc ccgctatcct
    43021 gaaaatgtct ctctagtgga tattacgctg cacactggtc ggacccatca aattagggta
    43081 cattttgctc atcttggttt tccacttttg ggagatgatc tgtatggtgg tcgattggac
    43141 cttggcatga ctagacaggc gctgcattgt caccatctta gctttacgca cccatttaca
    43201 gaaagtagaa gcgatcatac aatatgcttg acagatgact ttgagagcgt tatcatagat
    43261 ttacagaaaa aagatagagg ttagttaatg agtattcgta atttatttgg tggtttaagg
    43321 gaaaaaattg tcggcaaaaa catgaagatt gttttccctg agggaaatga tgagcgtgtt
    43381 gtacgtgcag cagcacgtct aaagtttgaa ggtcttgttg agccaattat tcttggtcag
    43441 gcagatgata ttcgcagcct gctaacacag ctaggctttg ctgagcagca ctatacaatc
    43501 attaacccaa atgattatgc tgattttgag aaaatgaaag cagcctttgt agagcttcgt
    43561 aaggtcaagg caacgcttga agatgctgat agactgctta gagatgtcaa ttactttggt
    43621 gttatgctgg ttaagctagg cttagcagat ggcatggttt caggggctat tcattcaaca
    43681 gctgatacgg tgcgtccggc gcttcagatt atcaagacaa agccaggcat ttctagaaca
    43741 tcaggtgtct ttttgatgaa tcgcgaaaat acagagcagc gtttagtgtt tgctgattgt
    43801 gccattaata ttgacccaac tgctcaggag ctcgcagaaa ttgcggtaaa cacagcagat
    43861 actgcgaaaa tttttgatat tgatcctaag gttgccatgc ttagcttttc aacaatgggc
    43921 tctgctaaag ccccacaggt tgaaaaggtt caagaggccg tccgtattgc taaggaattg
    43981 aggccagagc ttgctttaga cggtgagctt caatttgacg cagcctttgt accaagtaca
    44041 gcagcgatca aagcccctga ttcatcagtg gcaggccatg cgaatgtttt tgtcttccca
    44101 gatttacagt ctggaaatat tggctataag attgctcagc gcttaggcat gtttgatgct
    44161 atcggaccaa tcctgcaagg attgaacaag cctgttaatg atttatcacg tggctctagt
    44221 gcagaggata tttacaagct agctattatt acagcagcgc aagcgcttga aaatgagtct
    44281 atcaattaac tgctaatagc cattaagttc acaaggctta gctatagtag atgttgctta
    44341 aaacgagttg gataagccag ctcgtttttt cagaaagtga ggaaggaaat gacaaagatt
    44401 gcattagtaa caggcgcctc tgctggcttt ggtaaagcca ttgcagagca gttaatagcc
    44461 caaaacatca aggtgatcgg agcagcccgc cgcatagaaa agctaagaga gctagaaggt
    44521 atttttggtt ctgagaggtt ttatccgctt caaatggacg tttcagaacc aactgccatt
    44581 gataaagcac ttgcagaatt acctaaagaa tggcaggcca ttgatatttt agttaataat
    44641 gcaggactag ccttaggact tgataaggcc tatgaggctg atgtcgccaa ctggctaacc
    44701 atgattaata ctaatattat tgggcttatc tatttaacac gtcaggtatt accgcaaatg
    44761 gtaagcagca acaatggcat gatcatcaat atcggctcaa ctgctggcac tattccctat
    44821 ccgggagcta atgtttatgg ggcttcaaaa gcctttgtta agcagttttc gcttaattta
    44881 agggcagatt tagcaggaac aaatatcagg gtgaccaata ttgagcctgg cctttgtgag
    44941 ggaacagagt tttctcatgt tcgctttaag ggtgaccatg agcgtgttaa agcactttat
    45001 gcaggtgcac atgctattca gccaagggat atcgcaaata ctgtctcatg gattattgat
    45061 cagccagagc atgttaacat taaccgcgtg gaaatgatgc ctgtctcaca aagctatggt
    45121 tctcagcctg ttagccgtca tgactaagaa ttacaagagc agatgtaaaa ggattgtcga
    45181 agtgcaaccc aaaaagactt aaagcctagc tgttttatag cctggcttta agtctttttc
    45241 tctaattttt cttagaaatg atccgaaaga gaaggtccag atgtgacatc tgaccaccca
    45301 acaatggcct gccctgtttc ttccaaatag tgctgcagca taggcttgaa gtccaaaatc
    45361 atgtcataga ccccaacaaa ttgcttggta tcatcgtaca aggcttgata ttgctgcata
    45421 taaatatgat cctgtgaagc agtcggaata agatacagct tactgccagt tgccgccttg
    45481 tgcaaatcag tcaagatcca atcctcaatg acatcatgct tatcagaagc aaaaaaattg
    45541 ccattaaagc gatgattatc aaagatgatc tgcccctgat gatcagcaat tctagcctga
    45601 aggggaagat aggttaaaaa atgtggggct aaggcttggt aaaattgcat gaggtattta
    45661 gcaagtctta aagtttgctg actatcagta aaggtatgat cactaacggt aaatccttgc
    45721 tctttgtctg cctgattaaa ataaagtaca ggtagtgagg cttcaaggtt ctgaaaggta
    45781 aaaatggcct gagccttttt gagctgctca gtagtcagct gacggacaat agtgatatga
    45841 aacagatagc taaactcttg tgataaggtg gtaaaaaaag tcttttgcag attattctta
    45901 tcatcaacca gtgctaaggt ataaatcgtt ttagtcataa ggctatcata gctttatttt
    45961 gtttaaatag caatgaaaca gccttttagt ctacagactt agttgatagc ttaataaaag
    46021 aaagcaatat gaaaaaatga ttaaagcaaa ctagttgact tgttagttta aactttttat
    46081 aataaatcaa atgagaagat aatatgaggc ttagcctaag ctgctgagct tatctgataa
    46141 tcattcttct tagcactgag ataaccccct ttatcgatta attggagaat ctatgatacg
    46201 ttttaataat gtttccaaaa cctttggtca caccaaggtg ctgcaggagc aaagttttca
    46261 aatacagaat cgcgaatttt ttgtgctggt cggtccaagc ggctctggca aaacaaagct
    46321 cttaaaaatg atcaattgcc ttactgaacc aagctctggc gaaattctat taaacggaag
    46381 gccacaaaaa gagctagatt tgcgagatat gcgcttatct attggctatg ttcttcagca
    46441 aattgccctg tttccaaacc ttacagttgc tgaaaatatc gctattattc cagagatgaa
    46501 gaagtggtca gacaaagaga ttagaactaa gacagaggaa ttgttagata aggttggatt
    46561 gcctgcaagg gattatctaa atcgctatcc cagtgattta tccggtggag agcagcagag
    46621 gattggtatt gttcgtgcca tcatttctca ccccaaggtg ctgttaatgg acgagccgtt
    46681 ttcagccttg gatcctattt cacgcaagta attacaggac ttgatgttaa gtcttcacaa
    46741 ggagtttgat atgacaattg tctttgttac tcatgatatt gatgaggcta tcaagcttgg
    46801 agatcgtgtg gctgttttaa atgaagggca aattgttcaa ctggatcgac cagatgcgat
    46861 catagctgcg cctgctaatg attttgtagc aagtctattt ggaggtcgtg attatgccta
    46921 gtttactgat gaccttttgg gatcgttttg gtgattgggc aagggcatta ggagagcact
    46981 tgcagatttc tcttctttct ttgctggctg ccttgctgat aggcattccg cttgcagctc
    47041 tgttgagtaa aagtaagcgc tggtcaaata tcatcttgca gctgacaggt gtttttcaaa
    47101 ccattccttc cctagccttg ttgggactat ttatccctct aatgggaatc ggaactgctc
    47161 cagctgtaac agctttggtt atttatgcca tatttcctat tttacaaaat acgattactg
    47221 gcttaaatgc tattgatcca agtcttgtag aggccggaac agcctttgga atgaccaagt
    47281 gggagcgact gaaaatattt gaaattccta ttgctatgcc agttattatg tcaggtgttc
    47341 ggacctcagc agtgatgatt attggaacag ccaccctagc ttctttgatc ggagctggcg
    47401 gcttagggac ctttatccta ttaggaattg accgtaataa tgctcagctg attgtgattg
    47461 gtgctgtgtc gtcagccttg cttgcgatag tgtttaacag tcttttgtga taccttgaga
    47521 aggcctcact gaggcgtatt gcgataagct ttgctgcgac cttattactg ctcttaattt
    47581 cctatactcc aatgtttgtc aagcggtttg ttaatcagtc aaatactctg gtgattgctg
    47641 gcaagctagg agtagagccg gatattttga tcaatatcta taaagagctg attgaagacc
    47701 agtccaagct taaggttgaa ttgaaaccta attttggcaa gacaagcttt ttatacgagg
    47761 cgattaaatc aggagatatt gatatttatc cagaatttac aggaaccatc acctctagcc
    47821 tattaaagaa aaagcctaag ctttctaatg accctaatca ggtttactta gctgctaagg
    47881 aggggattgc tgagcaggat cagttgacgc ttttaaagcc ctttgcctat caaaatacct
    47941 atgcagtggc gatgcctgaa aaaatagctg acgaatttaa cattcaaagt atttcagatg
    48001 tgaagaaata tgaaaaacag ctaaaggctg gttttacact agaatttaag gatagagagg
    48061 acggctataa gggcatacag gataagtatg atctacattt atcagttgca acgatggagc
    48121 cagctcttag gtaccaagcc attcagtcag gaaacattca gctgacagac gcttattcaa
    48181 ctgatgctga gatcgtgaaa tatcagcttc gagtcttaaa ggacgataag cagctctttc
    48241 caccttatca aggagcgcca ttgatgaagg cttccttact aagaaagcac cctcatctca
    48301 aaacgattct caatcagtta tcaggaaaga ttactgaaga ggagatgcaa gcaatgaact
    48361 atgaggtgtc cgtaaagggc agagcagcta gccttgtggc acatgactac cttgtaaagg
    48421 ccggtcttat tgcaagaacc aaataagcag gcatgctagt cttattctgg actggcatgc
    48481 tttatttatg tgatttttag tctgtctggc tctgcaaggt gtgtgccaaa taaccgctcg
    48541 tttgatgtgt ggttattgat ttagtagcta aggattggaa tcttaaaata aaatccgaac
    48601 gtttgtctaa aaaaagcttt aaaaattgac aaaacataaa cgaaaggata aaataaatta
    48661 aggaaaggta acattttacc tagcgatgcc tcggacaagc ttgaggtcat aggaaggtca
    48721 ttttatatag aagcttatgt cagctgcaga tcagggaagt ccttgctgga ttagtagctg
    48781 aatgttgaaa aaggagagaa atgatgttta atgacatgcc tgtatttgat tatgaggata
    48841 ttcaattaat tcctaacaaa tgtatcatca atagtcgttc agaagcagat acgagtgtaa
    48901 gacttggtaa ttataccttt aagctacctg ttattcccgc caacatgcaa accattattg
    48961 acgaaacaat tgcagagcag ttggcaagag atggttattt ctatattatg caccgctttg
    49021 atgaggaggg gcgcaagccc tttatccagc gtatgcatga gcaacagctc atcgcctcta
    49081 tttcggttgg tgtaaaggat tatgaatacg atttcgtctc ttctttgaag gaggacgcac
    49141 ctgagtttat cacgattgat attgctcatg gccatgctga tagtgtgatc aaaatgatta
    49201 agcatattaa ggctgagctg cctgagacct ttgttatagc tggaaatgtc ggaacaccag
    49261 aggctgttcg agagctcgaa aatgctggtg ctgacgcaac aaaggtcggg attgggcctg
    49321 gtaaggtttg tatcacaaag gttaagacag gctttggaac aggggggtgg caattagctg
    49381 ctgtacgttg gtgtgctaag gctgctcgta agccgattat tgctgatggc ggtattcgta
    49441 ctcatggtga tattgccaag tcgattcgat ttggggcaac aatggtgatg atcggttcac
    49501 tctttgcagg tcatattgaa agcccaggca agatggtaga aatcgacgga cagtccttca
    49561 aggaatatta tggctctgcc tctgaatatc aaaaagggga gcataaaaat gtcgaaggca
    49621 agaagatttt gcttccaacc aagggtcatc tagctgatac tttaaccgaa atgaagcagg
    49681 atttacagtc atcaatctca tatgctggag gcagagattt ggagagcctg cgtcgtgtga
    49741 attatgttat cgtgaaaaat tctatttgga atggtgactc tatttaaagc cttggctaaa
    49801 gacctagtct aaataaggat aagcaagctg attgatgctg agaataagca cagcgtgtct
    49861 ataggacgcc tgaatgtcta gtagccagta aagcttttag gcttgctgat tggataggtc
    49921 attgtgccta tgtgcagcag ggctctaggg acttagataa aaaggagaca tgatgaggtt
    49981 actggaggag cgtatcctag ctgatggaac tgttttaggt gagacgattt tgaaggtgga
    50041 tcaattttta acacatcagg ttgactatcg cttgatgaag gaaatcggta gagtatttgc
    50101 tgatcaatat gctgatttgg gcattaccaa ggtggtcacc attgaagcct ctggtatcgc
    50161 accagcagtt tataccgcag aagctcttga ggttccgatg atttttgcca aaaagcacaa
    50221 aaatatcacg atgacagagg gaattttaac agcagaggtt tattccttta ccaaacaagt
    50281 gacaagtact gtttctattg caggaggact gctatcaaaa gaagataggg ttttgattat
    50341 tgatgacttt ttggctaatg gtcaagcggc aaaaggcttg attgatatca ttcatcaagc
    50401 aggggccaaa gctgttggca taggcattgt cattgaaaaa tcttttcagg ctggacggca
    50461 attgcttgag gatttgggag tagaggtcac ttcattggct cgtattaagc attttgacaa
    50521 tggaatagta agctttttgg aggctgatgc ctgatgactg cttcttatct ctcagcatta
    50581 agctttttac ttgtatagct ataccagctt tatttcagta gctattggct ggtgataagg
    50641 gatattggta tggcggtgca ttacggcgag ccgtgggcag ttgcccttgc ggctttacga
    50701 tttagtatag actatcaaga attgactgct tcctttttat cgagatgaat cattagacag
    50761 acaatcatga tttggcgtga aggctgcttt cagtaaacat tacatcatca aaaatcagct
    50821 aggtattcac ttagctgatt tttagtgctt ataatgtagc cgaaaggctc cctttaaccc
    50881 gtctgagata gtaacctgac catctttggt aatgataatg ccttccacct caggcagctt
    50941 atttagctga cttaggacaa aggaatgctc taagccaaaa agacgactac tccatagctc
    51001 accatcaagt gagaattggc tgacaatggt taggctagcc atattggtct tgataggata
    51061 gccgttgtga ggatcaagaa ggtgatgata agttttgtct ttgatttgta attgtctctc
    51121 gccgattcct gaggttacta cagatttatt gttaacctta atcacgccga catgctgtcc
    51181 tcttttttga ttggtctgct ggatcccaac gtaaaacaag ccattatgtc gttgcttgtt
    51241 ggtgccatgc acaaggacat ttccacctag attgataaga gcagcagtga taccgtcttt
    51301 aataagaaat gccatgagct tatcagcaat atagcccttt gctagggcac ctaagtcgat
    51361 agacatgccc ttttctttca aaaaaatact tccaaggctt tgatcta
//
LOCUS       DARYYD010000007        50812 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.007, whole genome shotgun sequence.
ACCESSION   DARYYD010000007 DARYYD010000000
VERSION     DARYYD010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50812
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.007"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            110..637
                     /locus_tag="TV188_000337"
     CDS             110..637
                     /locus_tag="TV188_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEL1533728.1"
                     /translation="MSVDDYRPTYAVEAVYDLRANDLLRQGITAVLVDLDNTLIAWDN
                     PDGTPEVRAWLDEMTIADISVVVVSNNTYSRVERAVSRFGVDFIARAMKPFAYGINKA
                     IDRYGFDRDEVIMVGDQLMTDIRASHRAGIKSVLVKPLVTSDAWNTKVNRWRERRVLA
                     KLEEKYGRLVYQKGI"
     gene            637..1755
                     /gene="yqeH"
                     /locus_tag="TV188_000338"
     CDS             637..1755
                     /gene="yqeH"
                     /locus_tag="TV188_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEL1533729.1"
                     /translation="MEELFCIGCGIQIQTTRKQEAGFTPAAALVKGIEAREIYCQRCF
                     RLRHYNDITDVHITDEEFLRLLHEVGDSDALVVNVIDIFDFNGSVIPGLSRFVAGNDV
                     LLVGNKKDILPKSVKDSKVTQWLTERAHEEGLRPLDVLLTSAQNKYAIKELIERIDQL
                     RQGRDVYVVGVTNVGKSTLINAIIQEITGDKDVITTSRFPGTTLDKIEIPLDDGSFIF
                     DTPGIIHRHQMAHYLSAKNLKFISPKKEIKPKTYQLNPEQTLFLGGLARFDFISGERQ
                     GFTAYFDNQLLLHRTKLEGADAFYDKQAGQLLTPPDKKELDDFPRLVRHEFLLDQKVD
                     VVFSGLGWIRVNANKETATKVAAWAPDGVAVVVRKAII"
     gene            1782..2123
                     /gene="yhbY"
                     /locus_tag="TV188_000339"
     CDS             1782..2123
                     /gene="yhbY"
                     /locus_tag="TV188_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEL1533730.1"
                     /translation="MLTSKQRAFLKAEAHSLKPIVQIGKNGLNDQIKTSIRQALDARE
                     LIKVTLLQNTDETIHEVAEILEEEIGCDTVLKIGRILILFKVSAKKDNILFKVSAKKD
                     NRKLSVKVKSI"
     gene            2207..2839
                     /locus_tag="TV188_000340"
     CDS             2207..2839
                     /locus_tag="TV188_000340"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEL1533731.1"
                     /translation="MALELLTPFTRVELEMEKKDSNRKQVGILGGNFNPVHNAHLVVA
                     DQVRQQLGLDQVLLMPEFKPPHVDHKETIDEKHRLRMLELAIQETEGLAIEEIELTRQ
                     GVSYTYDTMKLLIEQNPDVDYYFIIGADMVDYLPKWHRIDELIHMVQFVGVQRPKYKA
                     GTSYPVIWVDVPLLDISSSMIRDFIQSDRQPNHLLPKAVLDYIHKEGLYQ"
     gene            2836..3429
                     /gene="yqeK"
                     /locus_tag="TV188_000341"
     CDS             2836..3429
                     /gene="yqeK"
                     /locus_tag="TV188_000341"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEL1533732.1"
                     /translation="MMYQDYVGYRRDELLGKIAEQMSDKRFKHVLGVERAAIHLAERY
                     HCDPIKAGLAALLHDYAKECPDELFISLIDKYQLDPELLKWNNNIWHGMVGIYKLQED
                     LGLKDKGILRAIEIHTVGAAEMTILDKILYVADYIEEGRVFPLVDEARRIAELDLDKA
                     VAYETAHTVAYLASKAQPIFPQTIDTYNAFVHYLHEE"
     gene            3431..3784
                     /gene="rsfS"
                     /locus_tag="TV188_000342"
     CDS             3431..3784
                     /gene="rsfS"
                     /locus_tag="TV188_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEL1533733.1"
                     /translation="MRKEELLEIVIKAADEKRAEDMLALDLAGLTSLTDYFVIVTATN
                     SRQLEAIADNIRERVKEASGDASHVEGNSQTGWVLLDLNDVVVHIFSEDERYHYNLEK
                     LWHEAPAVELSHYLG"
     gene            3914..4657
                     /locus_tag="TV188_000343"
     CDS             3914..4657
                     /locus_tag="TV188_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1533734.1"
                     /translation="MQKNYDTFASVYDAIMDDSLYDKWTAFSLRHLPKNKEHQKLLEL
                     ACGTGIQSVRFAQSGFEVTGLDLSQEMLEVAKKRAQSAKKIITFVQGNMLDLSQVGSF
                     DVVTCYSDSICYMQDEIEVGDVFKEVYQVLNDGGIFMFDVHSIYQMDHLFPGYSYHEN
                     AEEFAMVWDTYKAEAPHSVVHELTFFIQAEDGHFLRFDEVHEERTYDILTYDILLEQA
                     GFKSFKVYADFEDQEPTKTSKRWFFVAQK"
     gene            4767..5867
                     /locus_tag="TV188_000344"
     CDS             4767..5867
                     /locus_tag="TV188_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEL1533735.1"
                     /translation="MTVTGIIAEFNPFHYGHQYLLSQAKGLKIVAMSGNFVQRGEPAL
                     VDKWVRAQMALENGADLVVELPFLVSVQSADYFAQGAVDILMRLGIDTLAFGTEQLLD
                     YQKLSRLYSEQAEHMTAYLATLPDHLSYPQKTQSMWEAFAGLSATGDRPNHLLALSYV
                     KASAGKKLQLQPIKRLGAGFHSEAKDQCLSSATAIRKHIADRAFVEKSSPNAALILRA
                     PQVTWEHYFPFLKYHILTAPDLTQFFQVNDELASRISAAIRSVATVDELVEAVATKHY
                     TKARVRRVLTYILVKAVEAPLPEGIHVLGFSKKGQAHLKTIKASVPLISRIGAKPWDQ
                     LTQRADTVYQLGHTDMPEQTWGCVPIRPEAMN"
     gene            6223..6930
                     /locus_tag="TV188_000345"
     CDS             6223..6930
                     /locus_tag="TV188_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1533736.1"
                     /translation="MKTVKEVSQLTGLSVRTLHEIGLLPPTMVGENGYRFYDAAALRR
                     LQDILLFRELAFPLKTIKQLLDSPSYDQQAALAAQIKMLELRKAHLEKVIAHARTLQK
                     GEETMTFDIYSKSQLEAFQLEAKERWGETEAYMAYEAKVNQPSAEQLIKDMGEIFSIF
                     GRMLDQPVAELAVQQQVKALQDYISQHFYDCSTEILSALGCMYLEDDRFRAAIDHMGG
                     AGTAAFVSRAISYYCQH"
     gene            7071..7787
                     /locus_tag="TV188_000346"
     CDS             7071..7787
                     /locus_tag="TV188_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1533737.1"
                     /translation="MGRKWANIVAKKTAKDGATSKVYAKFGVEIYVAAKQGEPDPELN
                     TALKFVIDRAKQAQVPKHVIDKAIDKAKGNTDETFVEGRYEGFGPNGSMIIVDTLTSN
                     VNRTAANVRAAYGKNGGNMGAAGSVSYLFDKKGVIVFKGDDADSIFELLLEADVDVDD
                     VEAEDGSITVYTAPTDLHKAILALRESGISEFQVTELEMIPQSEVTLEGDDLAVFEKL
                     VDALEADDDVQKVYHNVADV"
     gene            8009..8854
                     /locus_tag="TV188_000347"
     CDS             8009..8854
                     /locus_tag="TV188_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1533738.1"
                     /translation="MTIKRYLGLAGLAVLSVGMLAACGTKEKSASSTKDTPKEVIFAT
                     VGTTAPFSFEKEGQLTGYDIEVAKAVFKDAEKYKLQFKKTEWSSIFTGLDSGKYQMGG
                     NNISYTKERSVKYLFSYPIGATPSVLVVPKDSDIKSYDDIKGHSTQVVQGTTTAAQLK
                     AFNEEHADNPVELKFTNETITQMLTNLNEGKADFKIFDAPTVNAIIDNQGLDHLKTIE
                     LATSEQPFIYFIFSQDQEELQAFVNKRLEELTADGTLSKIAKKYLGGDYVPAKQDLKL
                     PTAKS"
     gene            9226..10071
                     /locus_tag="TV188_000348"
     CDS             9226..10071
                     /locus_tag="TV188_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1533739.1"
                     /translation="MNIKKAVGFVSLALASIALVACSGKQDDKNTLTIGVMTKTASDQ
                     ARWDKIEELLKKDKITLKYKEFTDYSQPNKAVANGEVDINSFQHYNFLDNWNKENKAD
                     LKAIAETYISPIHLFSGTSQDGKAKYQSVDELPDGAQIAVPNDATNESRALYVLQAAG
                     LIKLNVSGDKLATIANITENKKKLDIKELDASQTARALTSADAAIVNNSYAVPAKIDF
                     KTSLFKEKADENAKQWINIIAAQKDWEKSAKADAIKALIKAYHTDAVKKVVDKTSNGV
                     DVPVW"
     gene            10149..11519
                     /locus_tag="TV188_000349"
     CDS             10149..11519
                     /locus_tag="TV188_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEL1533740.1"
                     /translation="MTKTDQQYLTRLWEDQLTQDYLVSLGQLIASRSIFAQGIGLEET
                     AAYLKELFAQAGAEAIVDKTYAAPFVLARFNSSRPAAKTLIFYNHYDTVPADSDQKWT
                     SDPFTLTERDGYLFARGVDDDKGHIIARLTAVVRYLKEHADLPLNIVFMMEGAEESAS
                     VDLDRYLAKYADQLKGAELLIWEQGIRNEHDQLEITGGNKGILTFEMSVDSARCDIHF
                     KYGGVIESAAWYLLQALSSLRNHRGELLVPGIYQKVVPPTERELDLVETYAIENAQAL
                     KKLYGLELPMLQSERRQLLAAYYFQPSINIQGLWTGYQGQGVKTIIPSQATPKMEVRL
                     VPGLEPEYVFDQIRSYLLNKGFDQIKLTYTLGEMSYRSDLSSSAISQLIAAAQPFYPK
                     GLSLLPTSAGTGPMHTVFEALQVPIAAFGLGHSNSCDHAGDENIAIVDYCRHIALIEE
                     LITSYE"
     gene            11512..12576
                     /locus_tag="TV188_000350"
     CDS             11512..12576
                     /locus_tag="TV188_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEL1533741.1"
                     /translation="MSEPMIQLDHIDITFHQKKRVIEAVKDVTLHINQGDIYGIVGYS
                     GAGKSTLVRVINLLQQPTKGSITIDGELTFDQGKVQLSANSLREKRRDIGMIFQHFNL
                     MAQKTAKENVAFALRHSRLPKAERERKVTELLELVGLSERADNYPAQLSGGQKQRVAI
                     ARALANDPKILISDEATSALDPKTTKQILALLQELNRRLGLTIVMITHEMQIVKDICH
                     RVAVMQQGTLIEEGSVLDIFSNPREPLTQEFIKTATGIDEALEKINQQDIVKELPANA
                     ILAQLKYAGTSTDEPLLNQIYRQFEVTANILYGNIEILDQVPVGEMIVVFEGAAASIE
                     AAEKALHEAGVDVTILKRGA"
     gene            12577..13269
                     /locus_tag="TV188_000351"
     CDS             12577..13269
                     /locus_tag="TV188_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533742.1"
                     /translation="MLELFQAYLPNVYELGWSGDAGWGVAIWNTLYMTIVPFIVGGAI
                     GLFIGLLLVLMGPDGVIENRLVCWLLDKLTSIFRAIPFVILIAILASFTYLIMGTTLG
                     ATAALVPLTFATFPFFARQVQVVFSELDRGVIEAAQASGATFWDIVRVYLSEGLPDLI
                     RVSTVTLISLVGETAMAGAIGAGGLGNVAISYGYNRFNNDVTWVATLIILLLIFAIQF
                     IGDSLTRHFSHK"
     gene            complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TV188_000352"
     CDS             complement(13314..14699)
                     /gene="brnQ"
                     /locus_tag="TV188_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEL1533743.1"
                     /translation="MKEKNVYIVIGFMLFALFFGAANLIYPAFLGIYSGQNIPWSIIG
                     FCLTGVSLPLLGVIAVARSGSDDVESLARPISKWYAILYSSILYLSIGPFFAIPRTGA
                     TSFSVGIAPILGDSIINKAIYAVLFFGLSYFLAIRPSKLAESIGKFLTPTLLVVITIL
                     IIASFVHPAGDYGEAFNAGAGINNAFKDVPFIAGLIQGYGTMDALASLVFAILVIEAT
                     KQFGAKTDQEITKITLISGAIAILLLAFVYIFVGRIGATSQSLFPFVDGHFTLNNSAV
                     NGGQILSHASRFYLGSIGQAFLAIVIFLACLTTSTGLITSSAEYFHKLMPRVSHVAWA
                     TLFTLVSAFFYFGGLSVIINWSSPILYLLYPLTVDLIVLVLIQKSFGNAPLVYRTTIG
                     LTIIPALYDALATLSQLTKLFTLPDGLSYFFERLVPLGQFSMGWISFSILGFVLGLII
                     SKTKGLHPTAS"
     gene            15127..16341
                     /gene="sstT"
                     /locus_tag="TV188_000353"
     CDS             15127..16341
                     /gene="sstT"
                     /locus_tag="TV188_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HEL1533744.1"
                     /translation="MKRIRDLWVRTNLIKKIGIGVVIGLLLGILLPDVTAIGILGQLF
                     VGALKAIAPLLVFALVAQAISHQRSGQQTNMTLIIVLYLLGTFLAALVAVIANYLFPL
                     TLTLNTPVNTELSPPQGIVQVFQTLLLKLVDNPINALATANYIGVLAWALIFGLALKS
                     VPSDFKHLIKTAADVTSQIVVWIINVAPIGIMGLVFSTVSENGISILSDYALLILVLV
                     GTMLFVALVVNPLLAFVLTHQNPYPLVFRCLKDSGLTAFFTRSSAANIPVNLQLCEDL
                     GLSQATYLVSIPLGAMINMGGAAITINVLTLAAVNTFGIQIDFLTALLLSVVAAISAC
                     GASGVTGGSLLLIPVACSLFGISSDLAMQVVGVGFIVGVIQDSCETALNSSTDVLFTA
                     IAENAFWKQKKA"
     gene            complement(16695..17369)
                     /locus_tag="TV188_000354"
     CDS             complement(16695..17369)
                     /locus_tag="TV188_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEL1533745.1"
                     /translation="MLKRKTVGVLGLGIFGRTVARELSNYDQDVIAIDIRESHVKEIA
                     DLATKAAVGDITDKDFLIAVGVEQCDTVVIASGNNLESSVLAVMHCKKLGVPTIIAKA
                     KNKIFEEVLYGIGATKVITPERDSGKRVASNLLRHHIESIIYLEHGISMIEFTIPKSW
                     EGKSLSELDVRRKYELNIIGMRQKEVKTLDTNVQPFEPLEADTIIVAIANDHTFEKFD
                     YLGYLK"
     gene            complement(17379..18755)
                     /locus_tag="TV188_000355"
     CDS             complement(17379..18755)
                     /locus_tag="TV188_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEL1533746.1"
                     /translation="MKRSFFKSLSVTQRLTFSFAIVILIGSLLLSMPFTHYSNGPNTV
                     YLDHFFNVVSMVCVTGLSVVPVADVYNGIGQTIAMMLMQIGGLGLVTLIAVSTFALKR
                     KMRLSDQTLLQSALNRGDSKDLKKYLFFAYKVTFSLEAFAALVIMTDFIPRFGWKNGI
                     FNSIFLAVSAFCNAGFDNLGSSSLKDFVLNPTINAIITFLIISGGLGFAVWVDLGTAF
                     KKYFFERPHCYGITFKKFSNQSRLVLQTTLVILVLGTFLSWFLEKDNLNTIARYNLPQ
                     QLMVSFFQTVTMRTAGFATISYNDTLAPTNILYMIQMVIGGAPGGTAGGIKITTAAIT
                     FLLFKAELSGQSEVTFRNRIIANKTIKQTMTVLIFFFAVLMIGYILLLSVEPDIAPIP
                     LLFESISAIATVGVSMDVTPHLSSAGRLIIIVLMFVGRVGPITVLISLIQRKEKTIQY
                     ATTDILVG"
     gene            complement(19268..19990)
                     /gene="rsmG"
                     /locus_tag="TV188_000356"
     CDS             complement(19268..19990)
                     /gene="rsmG"
                     /locus_tag="TV188_000356"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEL1533747.1"
                     /translation="MTPQAFYLVLEQAGFALTNHQKEQFDTYFKLLVDWNRKINLTAI
                     TEENEVYLKHFYDSVAPLLQGYIPNEPLRLLDIGAGAGFPSIPMKIMFPKLDVTIIDS
                     LNKRIHFLQLLAKELGLEGVHFYHGRAEDFGQDKQFRGQFDLVTARAVARMQILSELT
                     IPFLKIKGKLIALKAQAADQELEEAKKALQLLFAKVLDHQPYQLPNGDGRYITLVEKK
                     KETPNKYPRKAGIPNKNHCKRL"
     gene            20126..20683
                     /locus_tag="TV188_000357"
     CDS             20126..20683
                     /locus_tag="TV188_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEL1533748.1"
                     /translation="MPMFLVIVALIGVLVVWLMVSYNGLVKARMHTKEAWSQIDVQLK
                     RRNDLIPNLVETVKGYANHEEKTLEKITSLRSRVADATTPQATMAASNELSKQVTSLF
                     AVAESYPDLKANSNFLKLQEELTNTENKISYSRQLFNTTTSHYNLKLESFPSNLVAKL
                     FGFKPSEFLQVPEAEKEVPKVDFTV"
     gene            20720..21613
                     /gene="htpX"
                     /locus_tag="TV188_000358"
     CDS             20720..21613
                     /gene="htpX"
                     /locus_tag="TV188_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEL1533749.1"
                     /translation="MLYQQISQNKRRTVILLFAFFVLLVVIGAAAGYLLADSYQLGAA
                     FALIIGAIYAFSMIFQSTSLVMGMNKAKEITVNDAPDFFHIVEDMALVAQIPMPRVFI
                     IDDPSLNAFATGSSPQNAAVAATTGLLKVMNREELEAVIGHEVSHIRNYDIRISTIAV
                     ALASAVTLISSIGGRMMWYSGGRRRDNDRNDNGFGAIMLIFSILSLILAPLAASLVQL
                     AISRQREYLADASSVALTRNPEGMIRALQKLSNSQPMTHPVDDASAALYINEPRKKEK
                     LSALFSTHPPIEDRIERLKHM"
     gene            21901..22434
                     /locus_tag="TV188_000359"
     CDS             21901..22434
                     /locus_tag="TV188_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEL1533750.1"
                     /translation="MLSVSDIRKRPEGIRFEREYDVKEALLIRDPQVIDINNVRASGR
                     AQFDDGLYLLEYQLGYQITLPSSRSMAPVVLDEMQTVQELFIEEADVASKQEMVDENL
                     VLVLSEDQLDLEESIIDNILLAIPLQVLTEAEKESQILPTGEDWAVLTEEQYQAQQKE
                     KAKDNSPFAGLQGLFDE"
     gene            22619..23305
                     /gene="covR"
                     /locus_tag="TV188_000360"
                     /gene_synonym="csrR"
     CDS             22619..23305
                     /gene="covR"
                     /locus_tag="TV188_000360"
                     /gene_synonym="csrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CovR"
                     /protein_id="HEL1533751.1"
                     /translation="MTKKILIIEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALE
                     KDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMTARDSIMDVVAGLDRGADDYIVK
                     PFAIEELLARIRAIFRRQDIESEKKTPSQGVYRDLVLNPQNRSVNRGDDEISLTKREY
                     DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDIPGKESYIQTV
                     RGMGYVIREK"
     gene            23309..24799
                     /locus_tag="TV188_000361"
     CDS             23309..24799
                     /locus_tag="TV188_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HEL1533752.1"
                     /translation="MAKQKKYKKTLPKRLSNLLFVLFFCIFSAFTLLAYISTNYFLLK
                     REKQTIFQAVNIVRVRLSEVDSNFTLENLAEVLYKNDRTHLKIDDANGSRIIRSERNI
                     TNTLNANEDIYVYNVDKQMIFTTDDEEASPGLNGTIGKVTKDHIEEQYKGFSMTQKVY
                     SNKTGKFVGYVQVFHDLENYYMIRARLFFWLLVVELFGVGLAYFIILIVTRNFLKPLN
                     NLHDVMRTISKNPDNLMLRSGISSGDEIEELSVIFDKMLDKIETHTRLQSRFISDVSH
                     ELRTPVAIIKGHIGLLQRWGKDDSAILDESLTAAAQEVDRMAIMINDMLDMIRVQGSF
                     EGHQNDTTVLESSIETVVGNFRVLREDFDFTWYSENQRTLAKIYKNHFEQALMILIDN
                     AVKYSRKEKKIVIELAVNASNEAVVKVKDRGEGISEEDIKHIFERFYRTDRSRNRTST
                     QAGLGIGLSILKQIVDGYHLHMEVESELNKGSVFILRIPLADHQGS"
     gene            24990..25484
                     /gene="nrdR"
                     /locus_tag="TV188_000362"
     CDS             24990..25484
                     /gene="nrdR"
                     /locus_tag="TV188_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEL1533753.1"
                     /translation="MRCPKCNYNKSSVVDSRQAEDGNTIRRRRECESCHTRFTTFERL
                     EELPLLVIKKDGTREQFSRDKILNGVVQSAQKRPVSSTDIENLISRIEQKVRTAYENE
                     VSSTVIGNLVMEELAELDEITYVRFASVYKSFKDLDEIEELLQQITNRVRGKKKSSVD
                     DEAY"
     gene            25468..26631
                     /locus_tag="TV188_000363"
     CDS             25468..26631
                     /locus_tag="TV188_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase loader"
                     /protein_id="HEL1533754.1"
                     /translation="MMKPIDTFSYIKHNQVQYDSSSLIQLYFPIIGNDAVAVYQYLVH
                     FFDDGSGAHKFSDILNHLQFGMKRLEEALVMLTAIDLLVLYQLPDAYLIKLHQPLGRE
                     AFLNNPIYRRLLEQKIGDVAVLELQMVIPNQARNISKTFSDVFGIDSQELKQPQPSKI
                     NFDLDSFQQLMRRDGLRFEDHQKDVISLYSISEQYHLTWFDTYQLAKATAVGGSIRPE
                     RMLVKKQQEGAQKTSESFSPAEQVVLRESKQDTPLVFLEKIKKARRARVTKDEKELLL
                     TLARMNFLDEVINIMVLYTFNKTKSANLHKTYLMKMANDFAYQRVLTAETAIIKTRAF
                     GERKQQAKSQQSNVPKWSNPDYQEKTSQEEQAKLEQFKQAALKRLENLGKSGD"
     gene            26632..27540
                     /gene="dnaI"
                     /locus_tag="TV188_000364"
     CDS             26632..27540
                     /gene="dnaI"
                     /locus_tag="TV188_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEL1533755.1"
                     /translation="MEKIGKMVEHLGQASRVASAELIEAILADQEVAEFIKAHQLSQA
                     EIKLSLSKFNQFLVERRKYQTGDETYIAKGYQPILVMNEGYADVSYLETRELVEAQRQ
                     AAIADRIHLVSLPRSYRRVSLSAVDVNNASRMQVFSELLDFVEQYPAAEQKGLYLYGD
                     MGVGKSYLMAAMAHELSEKKGVSTTLLHFPSFTIDVKNAISNGSVKEEIDAIKHVPVL
                     ILDDIGAEQATSWVRDEVLQVILQHRMLEDLPTFFTSNYSFADLERKWAKIKGNDETW
                     QAKRVMERVRYLARECHLEGVNRRQG"
     gene            27590..28900
                     /gene="der"
                     /locus_tag="TV188_000365"
     CDS             27590..28900
                     /gene="der"
                     /locus_tag="TV188_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEL1533756.1"
                     /translation="MVLPTVAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYT
                     TGEWLNRQFSLIDTGGIDDVDAPFMEQIKHQAHIAMDEADVIVFVVSGKEGVTDADEY
                     VSKLLYRTNKPVILVVNKVDNPEMRNDIYDFYSLGLGDSFPVSSVHGIGTGDVLDAII
                     DNLPIEEPVENDDVIRFSLIGRPNVGKSSLINAILGEERVIASPVAGTTRDAIDTSFT
                     DESGQAYTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDIVLMVINAEEGIRDYDK
                     RIAGFAHEAGKGMIIVVNKWDTIEKDNHTVARWEADIRDQFQFLTYAPIIFVSAVTKQ
                     RLNRLPELIKRISDSQSQRISSAILNDVIMDAIAINPTPTDKGRRLKIFYATQVSVKP
                     PTFVVFVNEEELMHFSYLRFLENQIRAAFTFEGTPIKLIARNRK"
     gene            29241..32333
                     /locus_tag="TV188_000366"
     CDS             29241..32333
                     /locus_tag="TV188_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1533757.1"
                     /translation="MARLIPGRIRNQGIELYEQGLVKIIDDRTDLLRAEVDTYQVQYG
                     INDEDIRCQCDYFERKQYCQHIAALEYFLKNNQKGKSLSEQLNNQLESKEETKKLTSF
                     GSLFLDSLHMNEDDTTKYRLLASGAKSPFSSDYWWSLKINRLPGEKAYVIRDIKAFIH
                     LVKVEGFYQIGKNYFESLSILQFDQASQELIRFLWRLSTHSDKLDYEWLFPNHARHLR
                     LPAGFFEEGIDLLTGLYEFSFETSSQTYSHLYVRPLEAEAGLFQFTVDVHRSSIELYI
                     KEKNIEYFFNNEYLLYMNTFYHLSLKQQKMVQAIRSLPIEADLAKHIHFDLDDQAKLA
                     ASLLEFRELGQVKAPKSFDIRDFQVTFVFDITEKGELTSQLIFDYGSIQISDKASLDQ
                     LPFASHYKKESSIYRALKRFGLSPQFFAKKALTDPKDWYRFFTEAVPYFESLGRVQLS
                     SKLQDQRLMESPQLTVKREGGLLDISFDFSTVCQTDIEKALATLFSDRSYFVNQSGKL
                     VVFDEETQKISRSLQELRAKQLANGHLQLEGIAATQLSHLFSDLSSVHFSEELETLIK
                     DLQHPDRFELGELAVKAKVRDYQLQGIKWLSVLDKYGFGGILADDMGLGKTLQIIAFL
                     SSRLTETSKVLILAPSSLIYNWLDEFSKFAPQIDAAVSYGLKPARDALIQEGHQVTIT
                     SYSSFRQDLETYQANDYDYLILDEAQMIKNAQTKIAQSLRAFDVKNCFALSGTPIENK
                     LLEIWSIFQIVLPGLLPSKKAFLKMEARDVSRYIKPFVMRRKKEEVLPELPELIEMNY
                     YNEMSDGQKAIYLAQLRQMQERLSAATDDDINRSKLEILSGITRLRQICDTPSLFMDY
                     QGGSGKLDNLRTLLLQIKENGHRALLFSQFKGMLALVKQEMDQLGLSSYTITGSTPAN
                     DRQEMTRAFNNGSKDAFLISLKAGGVGLNLTGADTVILIDLWWNPAVEMQAISRAHRI
                     GQEDNVEVYRLITRGTIEEKILELQENKRHLITTVLDGKQGLASMSVEEIKEILGLQP
                     "
     gene            32537..33130
                     /locus_tag="TV188_000367"
     CDS             32537..33130
                     /locus_tag="TV188_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533758.1"
                     /translation="MTKHAFPLVADGEPIIESARQMALYENEDLITNIAGSYQDKHYD
                     DIIRDHQFAEKTPVVSKGSLHHSPVVDEDHSYAQKARRQAKQDVKEKRQAYIAKNMAY
                     SPKQASKKGQSGAFSSKKPATELSRFTEKLNQESYILAELPRQYKEPQNTSQAAVKKN
                     NYDFLKRSQIYNHQEDRDHREKTIAQELNLSRFEDIK"
     gene            33174..34505
                     /locus_tag="TV188_000368"
     CDS             33174..34505
                     /locus_tag="TV188_000368"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEL1533759.1"
                     /translation="MSKTYHFIGIKGSGMSALALLLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFSEDNISPDMELIAGNAFREDNNSEVAYAMRHQLPFKRYHEFLGEFMKQ
                     FTSLGVAGAHGKTSTTGLLSHVLKHMTATSYLIGDGTGHGAADARYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTGLDDVFNAFNDYAKQVKKALFVYGEDEELRKISSPA
                     PIYYYGFEDTDDFVAFDITRTTNGSDFKVKHKGHAIGQFHVPAYGRHNILNATAVIAN
                     LFIAGFDMKLVAEHLKSFSGVKRRFTEKVINDTIIIDDFAHHPTEIIATLDAARQKYP
                     NKEIIAIFQPHTFTRTIALLDDFAHALNEADSVYLAPIYGSAREVDKGDVKVEDLAAR
                     VERPAKVISVDNVSPLLDHDNAVYVFMGAGDIQLYERSFEELLANLTKNNQ"
     gene            34553..35035
                     /locus_tag="TV188_000369"
     CDS             34553..35035
                     /locus_tag="TV188_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1533760.1"
                     /translation="MLIRHVNQTDWEIIADIEQANFSPQEAVAANVIKERAELISDTF
                     LVAVIANQFVGYIEGPVIAEPRLEDHLFHGVTKNPARGGYIAITSLSVAPGYQKQGIG
                     TALLAAMKDLAVAQDRLGIILTCHDYLIPYYEMNGFQDQGLSASKHGGSVWYQMLWQP
                     "
     gene            35144..36718
                     /gene="mltG"
                     /locus_tag="TV188_000370"
     CDS             35144..36718
                     /gene="mltG"
                     /locus_tag="TV188_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEL1533761.1"
                     /translation="MALTDFKDDEQRRQQQKSFKEKILAELEKANQIRKEKEEELFKK
                     DLEVQEAARRTAQLYAEYKRQEALSNNPKQASDIAAASQETTSTASTAHTSAIKLEET
                     AVATGDQALSPPEEPALSESLLKEEASVEGQTKKGGPVRRKTSKRQQTDRMAKKISTV
                     LISSIVAIIVVIGLAGTAYVYSALNPVDKNSDDFVQVEIPAGSGNKLIGQILEKEGLI
                     KNSTVFSFYTKFKNFTNFQSGYYNLQKSMSLEDIAQALQEGGTAEPTKPVLGKILIPE
                     GYTIKQIAKAIETNSRAKNRSKAKTPFHSKDFLNLVTSDAFIQEMAKKYPKLLGDLPS
                     KEVATYQLEGYLFPATYNYYKETTLKDLAEEMIAAANANLAPYYEAIAASGKTVNEVL
                     TLASLVEKEGSTDDDRRQIASVFYNRLNNGMALQSNIAILYAMGKLGEKTTLAEDAAI
                     DTTINSPYNVYINTGLMPGPVDSPGLAAIEATINPAATDYVYFVADVRTGEVYYAKTF
                     EEHSANVEKYVNSQIQ"
     gene            36791..37273
                     /gene="greA"
                     /locus_tag="TV188_000371"
     CDS             36791..37273
                     /gene="greA"
                     /locus_tag="TV188_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEL1533762.1"
                     /translation="MAEKTYPMTAAEKEQLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYDAAKDEQAFVEGQISTLETKIRYAEIIDSDAVAKDEVAIGKTVVVQEVGTQT
                     TDTYHIVGAAGADIFSGKISNESPIAQALIGKKTGDKVKIESPAATYEVTIISVDKTQ
                     "
     gene            complement(37514..38434)
                     /gene="yidC"
                     /locus_tag="TV188_000372"
     CDS             complement(37514..38434)
                     /gene="yidC"
                     /locus_tag="TV188_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003105894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1533763.1"
                     /translation="MKLKTNRILFSGLALSVLLTLTGCVGRDAKGHPEGIIWDYLGKP
                     VSFLIDYFANSTALGYGLAIIVVTIIVRTIILPLGLYQSWKASYQSEKMAYLKPFFEP
                     INQRIKNATSTEEKMAAQTELMAAQRENGVNPLGGIGCLPLLIQMPFFSAMYVAVQFT
                     KGVSTSTFMGIDLGHRSVLLTAVIAALYFVQSWLSMMAVPEEQREQMKAMLYTMPIMM
                     IVMSFYLPAGLGLYWLVGGFFSIIQQLITTYLLKPRLRKQIAEEFAKNPPKAYKSHQP
                     RKDVTAEKQALSTSKRTKLNRNAGKQKKRR"
     gene            complement(38517..38795)
                     /locus_tag="TV188_000373"
     CDS             complement(38517..38795)
                     /locus_tag="TV188_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEL1533764.1"
                     /translation="MKKVRLIVSGRVQGVGFRYSTYALALEIGDIYGRVWNNSDGTVE
                     ILAQASDPAKMTRFIQEIRKGPSKWAKVTYVDVNPSHFEDFHDFRISN"
     gene            39088..39825
                     /locus_tag="TV188_000374"
     CDS             39088..39825
                     /locus_tag="TV188_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEL1533765.1"
                     /translation="MIITSKANHLIKQAKKLLQKKHRKHSYLIEGWHLFEEAQRSGQE
                     LIHIFVLEEMAERLSGFDQVVIVSPEILKELTSSPNPQGIIAEVKLCQQALPTSYAGK
                     YLILEDIQDPGNLGTIIRTADAAKFDGVFLSEKSADVYNQKTLRSMQGSHFHLPIWRT
                     DIYQVSQVMQQQKIPVLATTLSQDSIDYKDLSARSSLALVLGNEGQGISPEMAALADQ
                     LIHISMPGQAESLNVAVAAGILIFSLI"
     gene            39864..40364
                     /locus_tag="TV188_000375"
     CDS             39864..40364
                     /locus_tag="TV188_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1533766.1"
                     /translation="MHYTEDTEYMEHVGHLIAHPRFQRLGDIVQHHHSTRLEHSVNVS
                     YSSYRLAKRLGLDAKSTARGGLLHDFFYYDWRVTKFNKGHAWVHPRIAVRNAKKLTAL
                     NKKEEDIILKHMWGATIAFPRYKESYIVTFVDKYWAVKEAMTPLRQKWTNRRFLRRKT
                     LQSHNH"
     gene            40383..41072
                     /locus_tag="TV188_000376"
     CDS             40383..41072
                     /locus_tag="TV188_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEL1533767.1"
                     /translation="MNDNVIYTQSDAGLSHFFAKVYSLVGMGVGLSAFVSYLMLFPFR
                     QNLVSIVLDHPMVYYGAAIVELVLVFVASGAARRNTPAALPLFLVYSALNGFTLSFII
                     AAYAQTTVLQAFISSAAVFFAMSLLGVKVKRDLSGIRKAMFAALIGIIVASLVNLFIG
                     SDLMSYVISLISVLIFSGLIASDNQMIKQVYQASNGQVGDGWAVAMALSLYLDFINLF
                     ISLLRLLGRND"
     gene            41466..41708
                     /locus_tag="TV188_000377"
     CDS             41466..41708
                     /locus_tag="TV188_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEL1533768.1"
                     /translation="MSTAIWILLIIVALTAGLFGGIFIARKQIEKEIGEHPRLTPEAI
                     REMMSQMGQKPSEAKIQQTYRNIVKQSKAAMTKGKK"
     gene            41888..42682
                     /gene="racE"
                     /locus_tag="TV188_000378"
     CDS             41888..42682
                     /gene="racE"
                     /locus_tag="TV188_000378"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEL1533769.1"
                     /translation="MDNRPIGFLDSGVGGLTVVSELMRQLPHEKIIYIGDSARAPYGP
                     RPAEQIREYTWELVRFLLTKHVKMIVFACNTATAVAWEEVKEALDIPVLGVILPGASA
                     AIKATSGGKVGVIGTSMTISSGIYQEKIQLLAPTVQVTSLACPRFVPIVESNEISSSV
                     AKKIVYETLAPLVGKIDTLVLGCTHYPLLRTIIQNVLGPQVKLIDSGAECVRDISVLL
                     NYFEINGSRDDEHRRHHFYTTAGSDSFQAIASAWLNQTIDVEHVTL"
     gene            42679..43668
                     /locus_tag="TV188_000379"
     CDS             42679..43668
                     /locus_tag="TV188_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEL1533770.1"
                     /translation="MSDNIYEYKDKDNWFIGKMTGHNLMAGWGVNHELIAKIDDMLGA
                     IAGDVDWESPVGYDVTVIRYASPFALISFVVGMINQKANRALKVVRHSGAILVTENER
                     LLAVHMPDDGVPVADFFGQQADGFGDTILIATRNEGKTKEFRRLFGDMGYRVENLNDY
                     PELPDVAETGVTFEENARLKAETISRLTGKMVLADDSGLKVDILGGLPGVWSARFSGP
                     DATDETNNAKLLHELAMVFDQKDRSAQFHTTLVVAAPGKDSLVVEADWHGYIATKPKG
                     EHGFGYDPLFIVGETGRHAAELAADEKNKLSHRGQAVKRLMEVFPAWQAKQSL"
     gene            43644..44165
                     /locus_tag="TV188_000380"
     CDS             43644..44165
                     /locus_tag="TV188_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEL1533771.1"
                     /translation="MASKTIIVMSDSHGDREVVAAIKGRYLGKVDAIFHNGDSELESS
                     DPIWEGIHVVAGNCDHDSGYKDSLVTSFDGLTIAQTHGHLYHINFTWDRLDYFAQETG
                     ADICLYGHLHRPAAWQLGKTVFINPGSVAQPRGEVNEKLYARVEWTAACIRVDYFTCQ
                     HKSYPSLSKEFKR"
     gene            44162..44623
                     /locus_tag="TV188_000381"
     CDS             44162..44623
                     /locus_tag="TV188_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1533772.1"
                     /translation="MIAKEFEAFLISHLDSYLIPAEELAIFINTHNADHVMLLLVSNG
                     FSRVPVITKEKQYVGTISISDIMTYQAKRQLTDWEMTQTNIGDMVNTKIETINITSSL
                     TEIMHKLVDFPFLPVVNDDNRFIGIITRKSILKAVNSLLHDFTDEYTITKK"
     gene            44620..45366
                     /gene="xerD"
                     /locus_tag="TV188_000382"
     CDS             44620..45366
                     /gene="xerD"
                     /locus_tag="TV188_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEL1533773.1"
                     /translation="MIAFIEPFLASKSLANNSQQSYRYDLRQFCQQVGQRINPETLAL
                     YQQSLSGLTVAAKKRKLSTVNQFLYYLYQQKALTDYFKMDDRIEASFSLKPQLTRLDT
                     SAFYAETAFLKGQLIALLILELGLTPSEIAGLRLADFDLGLQVLRLQSHRGIRVMTLS
                     KALLPFLEKATEAQQLYLFDHDAKPFSRQWFFNQLRDFLESIGCAELSAQSLREQFIL
                     NEKAAGKSIIEVAQLLGLKSPITLEKYYKM"
     gene            45366..46073
                     /locus_tag="TV188_000383"
     CDS             45366..46073
                     /locus_tag="TV188_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEL1533774.1"
                     /translation="MDIKVKDFEGPLDLLLHLVSKYEVDVYQVPIVEVIEQYLAYIET
                     LQAMRLELAGEYMLMASQLMLIKSRRLLPKLVDKEPDEEDLEQELLGKIEEYSRFKAL
                     SQELASQHDKRALLFSKPKQELIFEQAVLQKDKTVMDLFLAFSQLMAAKQEAFKYNHT
                     VIERDDYRIEDMMELIEARLELEQELTLTDLLKHCDHLNEAITLFLASLELIKRQLVG
                     IEQTSHFGQIVLRKEIQ"
     gene            46070..46609
                     /locus_tag="TV188_000384"
     CDS             46070..46609
                     /locus_tag="TV188_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEL1533775.1"
                     /translation="MTYLSQLEALLFVAGEEGLSLRQLASLLELTPTALQQQLDKLSQ
                     KYKEDKESGLCLIESSRTYKLVTKECLAPLLKDYAKAPINQTLSRASLEVLSIVAYKQ
                     PITRIEIDEIRGVNSSGALSKLVAFGLVQEAGKKEVIGRPNLYATTDYFLDYMGINHL
                     EELVDISSIAVEEQETTLF"
     gene            46846..47568
                     /locus_tag="TV188_000385"
     CDS             46846..47568
                     /locus_tag="TV188_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1533776.1"
                     /translation="MRINKYIAHAGLASRRKAEELIKRGLVTLNGQVITDLATTVKSG
                     DLVEVEGIPIYNEEKVYYLLNKPRGVISSVSDDKGRQTVIDLLPQVKERIYPVGRLDW
                     DTSGLLILTNDGDFTDKMIHPRNEIDKVYLARVKGVVTKESLRPLTRGVVIDGKKTKP
                     ARYRIIRVEPDKNRSIVELTIHEGRHHQVKKMFEVVGHLVDKLSRTQFGSLDVRGLKP
                     GEARRLSKKEVSQLHHLASTRK"
     gene            47565..47843
                     /gene="yidD"
                     /locus_tag="TV188_000386"
     CDS             47565..47843
                     /gene="yidD"
                     /locus_tag="TV188_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEL1533777.1"
                     /translation="MIKALLIAPVRAYQKYISPLFPPSCRYQPTCSAYMITAIEKHGA
                     KGVLMGLTRLLRCHPFAAGGEDPVPDTFSLKRHFITHEKIQDFDQKTD"
     gene            48002..48550
                     /locus_tag="TV188_000387"
     CDS             48002..48550
                     /locus_tag="TV188_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEL1533778.1"
                     /translation="MKQEIINRQYREKDSQNHVVLFQPQIPQNTGNIARTCAATNTPL
                     HIIRPMGFPIDDRKMKRAGLDYWDKLDIRFYDHLDEFLAQCDGSLHVISKFADRVYSD
                     EAYNDRQSHYFLFGREDTGLPEPFMRQYADRALRIPMNDEHVRSLNVSNAVCMIVYEA
                     LRQQAFKGLELSHTYEHDKLKS"
     gene            48929..49360
                     /locus_tag="TV188_000388"
     CDS             48929..49360
                     /locus_tag="TV188_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533779.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGDRDNKGENN
                     YYQVEKDLAMEIVSEFEGVKEISFLSPVQSKETGYWGTTATINKTNEISYSFSMTFSG
                     KLDDYSYYYDKCFKLVKRHKKLTLSQVDLTDIDIKYSKGGK"
     gene            49575..49988
                     /locus_tag="TV188_000389"
     CDS             49575..49988
                     /locus_tag="TV188_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533780.1"
                     /translation="MTVKKKVIILLGMVAILVMGGIFMFSYNQNQAKMLERQFNHEQK
                     RIVLYLLNHYSGINEIEFNDIENNSTTGSKNVLLTINNKIKMEVTFFNLNDDTDNYVI
                     SWNGKLSLIDKNPITHLSSIDKIKVKYWSNNDSNR"
     gene            49972..50226
                     /locus_tag="TV188_000390"
     CDS             49972..50226
                     /locus_tag="TV188_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533781.1"
                     /translation="MIVTDKNYNDIADGVYKVDAGKVIRPWRNGKTFKTNGKDYRVLK
                     TEDNPDNGMQAIAVAPIKGSEVGKSHIMIVYVKSSYWLAS"
     gene            50245..50643
                     /locus_tag="TV188_000391"
     CDS             50245..50643
                     /locus_tag="TV188_000391"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533782.1"
                     /translation="MKKQQSKRRKLIGIVALITILGGILTMNWFNDEKLNRERREQER
                     AAIYFSNTYENIHKIKIIGIDKNLKTGSMNKATIVNSKYYISVTFMGGEIYTGVEQAS
                     KDNEEFLNRRKKAENKTTLSKDIEVIYKEK"
     gene            50646..>50812
                     /locus_tag="TV188_000392"
     CDS             50646..>50812
                     /locus_tag="TV188_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533783.1"
                     /translation="MVSDKDYNKLSEKVYDVDANKVTISVRKNTDILNRYVKILKAED
                     TPDNGMQAMAVV"
BASE COUNT        14825 a         9313 c        11914 g        14760 t
ORIGIN      
        1 gtttgctttg aaagaggaaa cctgctttcc cttctttttc atttgatttt gaatgctatt
       61 tctggtgaaa tatggtaaaa taaaaagtac taattatttt ggagatgaaa tgagtgtcga
      121 tgattatagg ccgacctatg cggtagaggc tgtttatgat ttaagagcaa atgatttact
      181 gcgtcaaggt attacagctg tcttggtgga tttagataat accttaatcg cctgggataa
      241 tcctgatgga actccggagg ttcgtgcttg gttagatgag atgacgattg cagatattag
      301 tgtggtggtt gtgtcaaata acacgtattc acgtgtggag cgtgctgttt cgcggtttgg
      361 tgtggatttt attgctcgtg cgatgaagcc ttttgcctat ggtattaata aggctattga
      421 tcgttatggc tttgatcgtg atgaggttat tatggttggg gatcagctaa tgactgatat
      481 tagagctagt catcgggcag ggattaagtc tgtcttagtg aagcccttag taacatcaga
      541 tgcttggaac actaaggtta atagatggcg tgagcgtcgt gttttggcaa aattggaaga
      601 aaaatatgga aggctagtat atcaaaaagg gatttaatgg aagaattatt ttgtatcggc
      661 tgcggtatcc agattcaaac aacaagaaag caagaggctg gctttacacc tgctgctgct
      721 ttggtaaagg gaattgaagc tagggagatt tactgtcaac gctgctttag attacgtcac
      781 tacaacgaca ttacagatgt tcatattact gatgaagagt ttttgaggct gctccatgag
      841 gtgggagata gtgatgcctt ggtcgttaat gtgattgaca tttttgattt taatggctca
      901 gttattccag gcttatcacg ctttgttgct ggaaatgatg tgttattagt tgggaataaa
      961 aaggatattc ttccgaagtc tgttaaggac agcaaggtga cacagtggtt gacagaaaga
     1021 gctcatgagg agggcttgag acctcttgat gtcctgctga cgagtgcgca gaataaatat
     1081 gctattaaag agctgattga gcggatcgat caattgcgcc aagggcgaga tgtctatgtt
     1141 gttggggtga ctaatgttgg aaagtcgacc ttgattaatg ccattattca ggaaattact
     1201 ggggataagg atgtgattac aacgtcacgc tttcctggga ccactcttga taaaatcgaa
     1261 attcctttag atgatggtag ctttatcttt gatactcctg gtattatcca tcgtcaccag
     1321 atggctcact atttgtcagc taagaatttg aagtttatca gccctaagaa ggaaattaag
     1381 cctaaaacct accaattaaa tccggagcaa acgctttttt taggtggctt ggcgcgattt
     1441 gattttatta gtggtgaaag acaaggcttt acagcttatt ttgataatca attgctcctc
     1501 catcggacaa aattagaggg tgcagatgct ttttatgaca agcaggcagg gcaactgctg
     1561 actcctcctg ataaaaagga gcttgatgat tttcctaggt tggttcgtca tgaatttctg
     1621 ctggatcaaa aagtggacgt tgttttttct ggtcttggtt ggattcgtgt taatgctaat
     1681 aaggaaactg caactaaggt ggcggcttgg gctcctgatg gtgttgcagt agtcgttcgc
     1741 aaggcgatta tttaataaat aaaaagaaaa gtggaataaa aatgcttaca agtaaacaaa
     1801 gagccttttt aaaggctgag gcccatagtc ttaaaccgat tgttcagatt ggtaaaaatg
     1861 gcttgaatga tcagattaaa accagtattc gtcaagcctt ggacgctaga gagctgatca
     1921 aggttactct gttgcaaaat actgatgaaa cgattcatga ggtggcagag attttagaag
     1981 aggagattgg ctgtgatacg gttttaaaga ttggtcggat ccttattttg tttaaggtgt
     2041 cagctaaaaa agacaatatt ttgtttaagg tgtcagctaa aaaagacaat cgcaagctat
     2101 cagttaaggt caaatcgatc tagcgagagc ttttgctagg ctaagacgtt taggtctgct
     2161 gtgtcagtgc tgacaacatg agtaatggtg atattttgga gaggttatgg ctttagaact
     2221 tttgacgcct tttacgaggg tggaattaga aatggaaaaa aaagatagca atcgcaagca
     2281 ggttggtatc ttgggaggga attttaatcc tgttcataat gctcatttag tggtggctga
     2341 ccaggttcgt caacaattgg ggcttgatca ggtgcttttg atgcctgagt ttaagcctcc
     2401 gcatgttgac cacaaagaaa caattgatga aaaacatagg cttcgtatgc tggagctggc
     2461 tattcaggag acagaaggtc tagcgattga agagattgag cttacacgtc aaggggttag
     2521 ctatacctat gatacgatga agctgttaat tgagcaaaat cctgacgtgg attattattt
     2581 cattattggt gcggatatgg tagattattt gccaaagtgg caccgtattg atgagttgat
     2641 ccatatggtg cagtttgtcg gcgtgcaaag gcctaaatac aaggctggta cctcttatcc
     2701 ggttatctgg gtagatgttc ccttgctaga tatttcctca agcatgattc gtgactttat
     2761 ccaaagtgat cgtcagccta atcatttatt accaaaggct gttttagact atattcataa
     2821 agaaggcctg tatcaatgat gtatcaagat tatgttggct atagacgtga tgagctgtta
     2881 ggaaaaattg ctgagcagat gagcgataag cgctttaagc atgttcttgg cgtggaaagg
     2941 gctgctattc acttggcaga gcgttaccat tgtgatccga ttaaggctgg gttagcagct
     3001 ctactgcatg actatgccaa ggaatgtcct gatgagcttt ttataagctt aattgacaaa
     3061 tatcagctgg atcctgagct tcttaaatgg aacaataata tttggcatgg tatggttggc
     3121 atttataagc ttcaggaaga tttggggtta aaagacaaag gcattttgcg ggcaattgag
     3181 attcatactg ttggcgctgc tgagatgacg atattggata aaattctgta cgttgcagat
     3241 tatattgagg aaggtcgagt gtttcctttg gtggacgaag ctaggagaat agcagagctt
     3301 gatctagata aggcagttgc ctacgaaaca gctcatacag ttgcttattt ggcatcgaag
     3361 gctcagccga tttttccgca aaccattgat acttacaatg cctttgtgca ttatttacat
     3421 gaggaataaa atgagaaaag aagaactttt agaaattgtg attaaggctg ctgatgaaaa
     3481 gcgtgctgag gatatgctag ctcttgatct ggctggctta acaagcctaa cggactattt
     3541 tgttattgta acggcaacca atagtcgtca gttggaggcg attgctgaca atattcgtga
     3601 aagggttaag gaagcaagtg gtgatgctag tcatgttgaa ggaaacagtc agactggttg
     3661 ggtgctgctg gatttgaatg atgtggtcgt gcatatcttc tcagaagatg agcgttatca
     3721 ttataatctt gaaaagcttt ggcatgaggc tccagctgtg gagcttagcc actatttagg
     3781 ataaaaaagc agtcggctct gggctgtttt ttacaataag aaacagaaag gaagttggca
     3841 ttagaggcag gattgcctaa gaggtaagct cttgtagtac ttgctgtgag acgtgttgac
     3901 tgtatcaaat aatatgcaaa agaattatga taccttcgca tcagtttatg atgccattat
     3961 ggacgactca ctttatgata agtggacagc gttttcgctt cgtcatttac ctaaaaacaa
     4021 ggagcatcag aagcttttgg agctggcctg tgggactggt attcaatcgg ttcgatttgc
     4081 tcagtcaggc tttgaggtta ctggcttgga tcttagtcag gaaatgctag aggttgctaa
     4141 aaagcgagct caatcagcta agaagatcat tacctttgtg caaggtaata tgctggatct
     4201 gtcacaggtt ggatcgtttg atgtggtgac ctgctattcg gattcgattt gttatatgca
     4261 ggacgagatt gaggtgggtg atgtctttaa agaggtctat caggttttga atgatggcgg
     4321 tatttttatg tttgatgttc attctattta tcagatggat cacctttttc ctggttattc
     4381 ttaccatgaa aatgctgagg aatttgctat ggtttgggat acctacaagg ctgaggctcc
     4441 acattcagtg gtgcatgagc tgaccttttt tattcaggct gaggacggcc attttttacg
     4501 ctttgatgag gtacatgagg agcgtaccta tgatatcttg acctacgata ttttgctgga
     4561 gcaggctggc tttaagtctt tcaaggttta tgcagatttt gaggatcagg agccaacaaa
     4621 gacaagtaag cgctggtttt ttgttgcaca aaaatagctg tggctaagac aggtcagcga
     4681 gcggttttgt ggtttagtgg ctctgtattg agtctgtggc aggtcttgat gataatagga
     4741 atagatgcga aaggtaggac aatgttatga ctgtcactgg tattattgct gaatttaacc
     4801 cttttcatta tgggcatcag tacttactat cacaggcaaa ggggctaaaa attgttgcga
     4861 tgtcggggaa ttttgtgcag cgaggggagc cggcacttgt ggataagtgg gtacgcgcgc
     4921 aaatggcatt ggaaaatgga gctgaccttg tggttgagct cccttttctg gtttctgttc
     4981 aatctgcaga ttattttgct cagggagctg tggatatctt gatgagactt ggaattgata
     5041 cccttgcctt tgggactgag caattgcttg attaccagaa gctgtctagg ctatatagtg
     5101 aacaagcaga gcacatgact gcttatttgg ccaccttacc tgatcatcta tcttatccac
     5161 aaaaaacaca aagcatgtgg gaggcctttg caggccttag cgctactggt gataggccaa
     5221 accatctttt agcattatcc tatgtcaagg ccagcgcagg aaaaaagctg caattgcagc
     5281 cgattaagcg gctgggggca ggctttcatt cagaagccaa ggatcaatgc ttgtcatcgg
     5341 cgacagcaat tcgaaagcat atcgctgaca gagcctttgt ggaaaaatca tcacctaatg
     5401 cagctcttat tttgagggct cctcaggtga cttgggagca ttattttccc tttttaaaat
     5461 atcacattct gacagctcca gatttaacac agttttttca ggttaatgat gagctagcta
     5521 gtagaatcag cgcagctatt cggagtgtag cgacggtaga tgagctagta gaggcggttg
     5581 caaccaagca ctataccaag gcaagggtga ggcgtgtgtt gacctatatc ttggttaagg
     5641 ctgtggaagc cccattgcca gaaggcatac atgttttggg cttttcaaaa aaaggtcagg
     5701 ctcaccttaa aacaataaaa gcttctgtgc cgctaatcag tcgtattgga gctaagcctt
     5761 gggatcagtt gactcaacga gctgacactg tttatcagct gggacatacg gatatgccag
     5821 agcagacttg gggatgtgtg ccgataaggc cagaggcgat gaattgagcg ttactagaag
     5881 caaaccactg tctttgtatg acacgcttag aggaccagca agagcttcta agaagttcgg
     5941 gtaggcccta tagtcagttg gtaaaggtgt tattagagta gttcaggtga ctctttgctg
     6001 gtataaaggt cagatagact gcctttgctt gctaagctgt ttttcattgc tgataagaag
     6061 gatagttagc aagaactgtc agctcatgga agcttatcat ttaagatcaa aaaagttaag
     6121 tttgttcttg actctctccc tacgtgatag tctatacttg ttgttgaggt ggaaatagcc
     6181 atactagttg gtgctctttt gacctcacta aggaggaata ccatgaaaac cgtaaaagag
     6241 gttagtcaat tgacagggct tagtgtacgc accttgcatg agataggcct gctgcctcct
     6301 acaatggtgg gagaaaatgg ttatcgcttt tatgatgctg ctgccttgag acgtctacag
     6361 gacatcttac tgtttcgtga gctggcattt cctctaaaaa cgattaaaca attgctggac
     6421 agccctagct atgaccaaca agcagccctt gctgctcaga ttaagatgct agagctacgc
     6481 aaggctcatt tagaaaaggt tattgctcat gctaggactt tacaaaaagg agaagaaacc
     6541 atgacctttg acatttatag taagtcacag ctagaagcct ttcaactaga ggctaaggag
     6601 cgttggggag agacagaggc ctatatggct tatgaggcca aagtcaatca gcctagcgca
     6661 gagcagctta tcaaggatat gggggagatc ttttcaatct ttggtcgtat gctggatcag
     6721 cctgtagcag agctagcagt acagcagcag gtaaaggctc tgcaggatta cattagtcaa
     6781 cacttttacg attgctcaac tgagatctta tcagctcttg gttgtatgta tcttgaggat
     6841 gaccgcttta gagcagctat tgatcatatg ggtggtgcag gaacggcagc ctttgtcagc
     6901 cgagctatta gctattattg tcagcactaa gctgctaagt gcatatcact ggctgctatt
     6961 cctaatttac gaaccctttt gaaagtgcta taatgataga gttaaagcta atttaactct
     7021 gcttattcta aaaagagctt aatcaaaatt gtattttaga ggagaatcca atgggacgta
     7081 aatgggcaaa tattgttgca aaaaaaactg ctaaagacgg tgcaacatca aaggtttatg
     7141 ctaagtttgg tgttgaaatc tatgtggctg ctaagcaagg agagcctgat cctgagttga
     7201 atacagccct caagtttgtc attgatcggg caaagcaggc acaggtgcca aagcatgtta
     7261 ttgataaagc cattgataag gcaaagggta atactgatga gacctttgtt gagggacgct
     7321 atgagggctt tggaccaaat gggtcaatga ttatcgtaga caccttgacg tcaaatgtga
     7381 accgtacagc tgccaatgtt cgtgctgcct atggtaaaaa tggtggtaat atgggagcgg
     7441 ctggatcagt ttcttactta tttgataaaa agggggttat cgtttttaag ggcgatgacg
     7501 cagacagtat ttttgagttg ctcctagagg ctgatgttga tgttgatgat gtagaggcag
     7561 aagacggatc aattactgtt tatacagcac caacagatct gcataaggct attcttgctc
     7621 ttcgtgaatc aggtatatca gagtttcagg tgactgagct tgagatgatt cctcagtctg
     7681 aggtaactct tgagggggat gaccttgctg tttttgaaaa gctggttgat gcccttgaag
     7741 cagatgatga tgtgcaaaag gtctatcata atgtagctga tgtctaagcc ctaagactat
     7801 catgtaaaca gagccgagat ttctcggctc tgttcatttt cctataatcg agctctgtag
     7861 aggctgagta tgactatctg ccttttatgg taacagctga cgtagtagct gatcgtcaca
     7921 tggtgctgct ttagcagagt tcaatcatta gtatcttatg ataaaaaatg ataaactaat
     7981 cttatgaatc ataaaggagt agaggacaat gacaataaaa cgttatttag gtttagctgg
     8041 cttggccgta ctgtctgtgg gtatgctagc ggcatgtggc acaaaggaaa aatcagcttc
     8101 gagcacaaag gacacaccaa aagaggttat ctttgcgaca gttggaacaa ctgccccctt
     8161 ctcatttgaa aaggaaggac aattgacagg ctatgacatc gaagtggcta aggctgtgtt
     8221 taaagatgct gagaagtaca agcttcaatt taagaaaaca gaatggtcat ctatttttac
     8281 gggcttagac tctggaaaat atcaaatggg cggcaacaat atttcataca ctaaggaacg
     8341 ctcagtcaaa tatttgtttt cttatccaat tggtgcaact ccgtcagtgc tagttgtgcc
     8401 aaaggatagt gatatcaagt cttatgatga tattaagggt cattcaacac aggtggtgca
     8461 gggaacaacg actgctgctc agctaaaggc cttcaacgaa gagcatgctg ataatcctgt
     8521 tgagctaaag tttaccaacg aaaccatcac tcaaatgcta accaatctga atgagggcaa
     8581 ggctgatttt aagatttttg atgccccaac ggttaatgct atcattgata atcaaggctt
     8641 agatcacttg aaaacaattg agctggcaac aagcgagcag ccctttatct actttatttt
     8701 tagtcaagat caagaggagc tacaggcctt tgtcaataag cgcttagagg agctgacagc
     8761 tgatggcaca ctcagtaaaa ttgctaaaaa gtatctaggt ggcgattatg ttccagctaa
     8821 gcaggatttg aagcttccta cagcaaaatc ctaaattggc tgaaagacca acaacgatat
     8881 aagcgactat ttggcttaaa accaagctgt tagaaggctt gcttttaagc ctttttaaat
     8941 gcctttgttg cctactaggg cttttaaagt aacctagtgt ctagggcagc agctattaag
     9001 atctgttgcc ttatttcgag ggtggttttg aggtaaaagg tctgtagtaa gagccttgac
     9061 ttaattaatg cttgcttggc tagtctgtca gttggtttag gtttggtgtt ttgactagag
     9121 attatagcta atggctatac cttatcctaa aatttaccaa tttgaatgcg agagctattt
     9181 cgtataaaat aaactcattg aaaaaaagaa attgaggaac aaaatatgaa tattaaaaaa
     9241 gctgtcggct ttgttagcct tgctcttgct tcaatagctc tagtagcctg ctctggtaag
     9301 caggacgaca aaaatacctt gaccattggg gtaatgacta aaacggcatc tgatcaagcc
     9361 agatgggata agattgaaga gctgctgaaa aaggataaga tcactctaaa gtataaagag
     9421 ttcacagatt attctcagcc caacaaggca gttgctaatg gtgaggttga tatcaattca
     9481 ttccagcact ataacttttt ggataattgg aataaggaaa ataaggcaga tttgaaggct
     9541 attgctgaaa cctatatcag tccgattcat ctcttttcag ggactagtca agacggtaag
     9601 gctaaatacc agtcagtaga tgagcttcca gatggtgcgc aaattgcagt gccaaacgat
     9661 gcaacaaatg aaagccgtgc cctgtatgtg cttcaagcag ccggcttgat caagctcaat
     9721 gtgtcaggtg ataagctggc aaccattgca aatattacag aaaataagaa aaagctagat
     9781 attaaagaat tagatgcgag tcagacagca cgtgccttga cgtcagctga tgccgctatt
     9841 gttaataata gctatgccgt tcctgcgaaa attgatttta aaacctctct ttttaaggaa
     9901 aaggctgatg agaatgccaa gcaatggatt aatatcattg ctgctcaaaa ggattgggaa
     9961 aagtctgcta aggcagacgc gattaaggca ttaatcaagg cctaccatac agatgctgtg
    10021 aagaaggttg tggataaaac ctcaaatggt gttgacgtcc ctgtatggta agggataata
    10081 ggtaatatta gtaacaggag gattgaggcg tgtgaagcac gccctttctt atattagggg
    10141 gaaaacacat gacaaaaacg gatcagcagt acttaacaag gctttgggag gatcagctca
    10201 cacaggatta tcttgtgtcg ttggggcaat tgattgccag taggtctatt tttgctcaag
    10261 gtatcggctt agaagagaca gcagcctacc taaaggagct gtttgctcag gctggtgctg
    10321 aggctattgt tgataagact tatgcagctc cctttgtcct agcacgcttt aatagctcta
    10381 ggccagctgc taagacactg atattttaca atcattacga tacagtgcca gcagatagtg
    10441 atcaaaagtg gacgagtgat ccctttacct taacagagcg tgatggctat ttgtttgcgc
    10501 gcggcgttga tgatgacaag gggcatatca ttgcgagatt gacggctgtc gtcaggtatc
    10561 taaaggagca tgcagacctt ccgcttaata ttgtctttat gatggaggga gctgaggagt
    10621 cagcttcggt agatttagat cggtatctgg ctaaatacgc agaccagcta aagggagcag
    10681 agcttttgat ttgggagcag ggcattcgta atgagcatga tcagcttgaa ataactggcg
    10741 gcaataaggg gattttgacc tttgagatgt cagtagatag tgctcgttgt gatattcatt
    10801 ttaaatatgg tggtgttatc gagtcagcag cctggtattt gcttcaggcc ctatcaagcc
    10861 tgcggaacca tcgtggggaa ttgctggtgc ctggtattta tcaaaaagtc gttccgccaa
    10921 ctgagcgaga gctagattta gttgagacct atgcaattga gaatgctcaa gctctaaaaa
    10981 agctttacgg actggagctt cctatgttac aatcagagcg tcgtcaattg ttagcagctt
    11041 attactttca gccctccatt aacattcaag ggctgtggac tggctatcaa ggacaaggag
    11101 ttaagaccat cattccttca caggctactc ctaaaatgga ggttcgtttg gttcctggct
    11161 tagagcctga gtatgtcttt gatcagatta ggtcttattt gctcaataag ggctttgacc
    11221 agatcaagct gacctatact ttgggtgaga tgagctatcg gagtgatctt tcatcgtctg
    11281 ctattagtca gctgattgca gcagctcagc ctttttaccc taaggggcta tctcttttgc
    11341 cgacatcggc aggaacaggc cctatgcata ctgtttttga agccctgcag gttccgattg
    11401 ccgcttttgg cttagggcat tctaatagtt gtgatcatgc aggtgatgaa aacattgcta
    11461 ttgtagatta ttgtcggcat attgcattaa tagaggagtt aataacatct tatgagtgaa
    11521 ccaatgattc aattagatca tattgatatt acctttcacc aaaaaaaacg tgtgattgaa
    11581 gctgttaagg atgtaacgct tcatatcaac caaggggata tttatggcat tgttggctat
    11641 tctggtgctg gcaaatcaac cctagtgcgt gtgattaacc tgctgcagca gccaacaaag
    11701 ggaagcatta caattgatgg ggagctgacc tttgatcaag gcaaggttca gctgtctgct
    11761 aatagcctac gtgagaagcg tcgtgatatt ggcatgattt ttcagcattt caatcttatg
    11821 gcacaaaaaa cagctaagga aaatgttgcc tttgctctgc gccattctcg attgcctaag
    11881 gctgaaagag aaaggaaggt gactgagcta ttagaattag taggcttatc tgagcgtgca
    11941 gacaattatc cagcacagct gtctggtggt caaaagcaga gggttgctat tgcgcgtgcc
    12001 cttgccaatg accctaaaat attgatttct gacgaggcca cctcagcgct agatcctaaa
    12061 acgaccaagc agattctcgc tcttttgcag gaattaaacc gcaggctagg cttaacgatt
    12121 gtcatgatta cgcatgaaat gcagattgtc aaggatattt gtcatcgtgt ggctgttatg
    12181 cagcagggaa ccttgattga agaaggcagt gttttggata tcttctcaaa tccaagagag
    12241 cctttgacgc aggagtttat caagacagcg actgggattg atgaggcact tgagaaaatt
    12301 aaccagcagg atattgtcaa ggagctacca gctaatgcta ttttagctca gctcaagtat
    12361 gcagggacat cgactgacga gcctttactt aaccagattt atcgccagtt tgaggtgacc
    12421 gctaacattc tttatgggaa tattgaaatc ttagatcagg taccagttgg tgagatgatt
    12481 gttgtttttg aaggtgcagc agcaagtatt gaggcggcag aaaaagcctt gcatgaggct
    12541 ggcgtcgatg tcactatttt aaagagaggg gcttaaatgt tagaattgtt tcaggcttat
    12601 ttgccaaatg tttatgagct tggctggtct ggtgatgctg gctggggagt agccatttgg
    12661 aataccttgt acatgacgat cgttccattt attgtaggtg gagctattgg tttatttatt
    12721 ggtcttttgc tggtactgat ggggccagat ggggtgattg aaaatcgact ggtttgttgg
    12781 cttctagata agctcacgtc gatttttcgg gctattccct ttgttatatt aattgctatc
    12841 ctggcaagct ttacttatct gattatgggg acaaccttgg gtgcaaccgc agctctggtg
    12901 cctttgacct ttgcaacctt tccttttttt gcgcgtcagg tccaggttgt tttttcagag
    12961 cttgatagag gtgtgattga ggctgcacag gcttcaggag ctaccttctg ggatattgtc
    13021 agggtttatc tgagtgaggg cttaccagac ctgattcgtg tgtcaacagt gaccttgatt
    13081 tccttggttg gtgagacagc gatggcagga gctattggtg ctggagggct tggtaatgtc
    13141 gcgatttcct atggctataa ccgttttaac aatgatgtga cgtgggttgc cacccttatt
    13201 attctcttgc tgatctttgc gattcaattt attggagaca gcctgacaag gcattttagt
    13261 cacaaataat aaaactgctc agagctttat tagctccaag cagtttttta atgtcatgat
    13321 gctgtagggt gaagtccttt tgtcttgctg atgatgagac ctaagacaaa gcctaggatg
    13381 gaaaagctaa tccagcccat tgaaaattgg ccgagtggaa ccaacctttc aaagaaatag
    13441 gaaagaccat caggcaaggt aaagagcttg gttagctgtg agagggtagc tagggcgtca
    13501 tacaatgctg gaatgatggt aaggccaatc gtcgttctgt agacaagagg ggcattgcca
    13561 aatgactttt ggatcagaac aagaacaatc aaatcgacag tcagtgggta caagaggtac
    13621 aaaataggag atgaccaatt gataataact gacaagccac cgaagtagaa aaaggcagat
    13681 acaagggtaa atagagttgc ccaagcaaca tgtgataccc ttggcattag cttgtggaaa
    13741 tactctgcac ttgaggtgat aagaccggtt gaggtggtca gacaggctag gaaaatcaca
    13801 atcgcaagga aggcttgccc aatgctacct aggtaaaatc gtgaggcgtg gcttaaaatt
    13861 tgtcctccat tgacagcgct gttgtttagg gtaaaatgcc catcaacaaa agggaaaaga
    13921 gattgtgagg tcgcaccgat ccgtcccaca aaaatataaa caaaggctag cagcaaaatg
    13981 gcaatggccc cagagataag ggtgatttta gtgatttcct gatcggtttt agcgccaaat
    14041 tgcttggttg cttcaatgac taatatggca aaaaccaagg aagctaaagc atccatagtg
    14101 ccgtagcctt gaataagacc tgcaataaag ggaacgtcct taaaggcatt gttgatacct
    14161 gctccagcat taaaggcttc gccatagtct ccagctgggt gaacaaagga ggcaatgatt
    14221 aaaatagtaa tcacaaccaa tagcgtcggt gtcagaaatt taccaatgct ttctgctagc
    14281 ttgcttggtc taatagccaa aaagtaggat aagccaaaaa atagcacagc atagatggct
    14341 ttattgatga tgctatctcc taatatcggg gcaatcccaa cagagaagga ggtagcgcct
    14401 gttctaggaa tagcaaagaa aggaccaatg gacaaataca ggattgatga gtaaaggata
    14461 gcataccatt ttgaaattgg ccgagccagg ctttcaacat catcagagcc tgaccttgca
    14521 acagcaatga caccaagcaa gggtaaagac acaccagtca agcaaaagcc aataatggac
    14581 caagggatat tttgtcctga atagatgcca agaaaggccg gataaatgag atttgctgca
    14641 ccaaaaaaga gagcaaacag cataaagcca ataacgatat agacattttt ttctttcatt
    14701 gccttaataa gtctttcttt tgatataaat ttgaagattc caataattta attgaaaact
    14761 cttgaaaata ataacagttg ctattatacc taagtttctg aaagtcgtca acaattatca
    14821 gacgatagat caagctgaga cctaaaaaag cgctgagggg tatctggata aagcagctta
    14881 gcctttattt tacagctttt gagaggactt gctcacctgc tgaatctcta atcaagcctt
    14941 gctagaaaga gtggtccaag gcttggggag ctttgatgag agatttgctg tcttattgat
    15001 gaaagaatct gtcagctagc ttatgatggt ggggctgcag cggtgtataa catccttgct
    15061 tgatttgacg aataactaaa attatattat gataaaaaac atctaacttg agcgaggata
    15121 aataacatga aaagaattcg tgacttatgg gtcaggacca acctgattaa aaaaatagga
    15181 atcggggtcg ttataggact tcttttgggg attttattgc ctgatgtgac agcgattggc
    15241 attttggggc agctttttgt tggggcttta aaggcgatag ctcctctctt ggtttttgcc
    15301 ttggtggcac aagctatctc tcaccaaagg tcaggacagc aaaccaatat gaccttgatt
    15361 attgtgcttt atttgcttgg aacctttctg gcggccttgg ttgctgttat tgctaattac
    15421 ctatttcctc taaccttaac cttaaatact ccggttaata ctgagctttc accaccacaa
    15481 ggtattgttc aggtctttca gacgctttta ttaaagctag tggataatcc tattaatgct
    15541 ttagctactg ccaattatat tggtgtctta gcttgggcat tgatctttgg cttagccctc
    15601 aagtctgttc cttcagattt taagcatttg atcaaaacag cggcagatgt gacctcacaa
    15661 attgtcgttt ggattatcaa tgtcgcaccg attggcatta tgggcttggt cttttcaact
    15721 gtttctgaaa atggcattag cattttgtct gattatgctc ttttaattct ggtcttggtg
    15781 ggaacgatgc tctttgtagc gctagtggtt aaccctttgc ttgcctttgt cctgactcat
    15841 caaaatcctt atcctcttgt ttttagatgt ttaaaggatt ctggccttac agcctttttc
    15901 acaagaagct cggcagcaaa cattccagtc aatttgcagc tatgtgagga cttgggacta
    15961 agtcaggcga cctatttagt atctattccc ctaggtgcaa tgattaatat gggaggagca
    16021 gccatcacga tcaatgtttt gacacttgct gctgtcaata cctttggtat tcagattgat
    16081 tttctgactg ccctgctttt gagtgtggtt gcggctatct cagcctgtgg cgcttctggt
    16141 gttacaggag gctctctcct tcttattcca gtggcatgta gcctttttgg gatctcaagt
    16201 gatttggcta tgcaggttgt cggggttggc tttattgttg gtgtgattca ggattcctgt
    16261 gaaacagccc ttaattcatc aactgatgtc ctctttacag ccattgctga aaatgccttc
    16321 tggaagcaaa agaaggccta gccttataat acagcttatt agtaaaaaaa gaggctggga
    16381 caaaaagagc tgcactttag aaagtcttaa cctaatatac tttatgacct agtctcatgc
    16441 attaaaaaag cgaacaagtc tagttttcgg aatctctgaa aactggctcc atgtcaactg
    16501 tagtgggtga cttatagcta agcacgagag gagacgaagg ttgtcttctc ttttgtgatg
    16561 ttcaaagcga ggaagatgcg ttttttaggc tctataatct ccacagtggc cttacccact
    16621 acagaaatta tagagcctga aaactagact tgttcgttta ttttaggtca gacttttgtc
    16681 ccagacccgt tatgttattt gaggtagcct aggtagtcaa acttttcaaa ggtatgatcg
    16741 ttagcgatag caacaataat ggtgtcagcc tcaagtggtt caaagggctg aacattggtg
    16801 tctagggttt tgacctcttt ttgacgcatg ccaataatat taagctcgta ttttcgacga
    16861 acatcaagct ctgagagcga tttgccctcc cagctcttag gaatggtgaa ttcgatcatg
    16921 gaaatcccat gttctaggta gataatgctc tcaatgtgat ggcgtaagag atttgaggcc
    16981 actcgctttc cagagtctct ttcaggggtg ataaccttgg ttgctccaat gccatataag
    17041 acctcttcaa aaattttgtt tttagccttt gcaataatgg ttggaacccc taatttttta
    17101 cagtgcatga cagctagtac agaggactct agattgtttc ctgatgcgat gacaactgtg
    17161 tcacattgct caacccctac tgcgattaaa aaatccttat cagtaatatc gccaacagct
    17221 gccttggtcg ccaaatcagc aatttctttc acgtggcttt ctctaatatc aatggcaatg
    17281 acatcttggt catagttgct taattctctg gcaacggtgc ggccaaaaat ccccaggcca
    17341 agaacaccaa cagtttttcg ttttaacatg atttctcctt aacccactaa aatatcagta
    17401 gtggcatatt gaatggtttt ttctttacgt tgaattagac taatcaaaac agtaattggt
    17461 ccgacacgac caacaaacat cagcacaata atgattaggc gtcctgcact tgataagtgc
    17521 ggtgtgacgt ccattgatac cccaaccgtt gcaatagctg aaatggattc aaataaaagc
    17581 ggaatagggg cgatatctgg ctctacactt agcagtaaaa tgtagccaat catcaagacc
    17641 gcaaaaaaga aaatcaaaac agtcatggtt tgcttaatgg tcttgttggc gatgatacgg
    17701 ttacgaaagg ttacctcaga ttgaccggaa agctctgcct taaacaataa aaaggtgatg
    17761 gcagcagttg tgattttgat tcctccggca gtaccacctg gagctccacc gataaccatc
    17821 tgaatcatat aaagaatatt ggtaggagcc aaggtatcat tataagaaat agtcgcaaag
    17881 cctgcagttc tcatggttac cgtttggaaa aaggacacca tcagctgctg cggtagattg
    17941 tatctggcaa tagtattgag attgtccttt tccaaaaacc atgataaaaa ggtacctaaa
    18001 acaaggataa ctagggttgt ttgcagcact aagcgtgact gattagaaaa ctttttaaag
    18061 gtgatgccat agcagtgagg cctttcaaag aagtattttt taaaggcagt gcctaaatca
    18121 acccaaacag caaagccaag tccgccagaa ataattaaga aggtgataat agcattgatg
    18181 gtagggttta acacaaagtc ctttaagcta gatgatccta gattatcaaa gcctgcatta
    18241 caaaaggcag agacagccag aaagatactg ttaaagatac catttttcca gccgaaacga
    18301 gggataaagt cagtcatgat aaccaaggca gcaaaggcct ccagtgagaa ggtgacctta
    18361 taggcaaaaa agaggtattt ttttaagtcc ttactgtcac cacgattgag ggcggattgg
    18421 agcaaggttt gatcacttaa acgcattttg cgcttgagtg caaaggtgct gaccgcaatc
    18481 agagtgacca atccaagtcc gccaatttgc atgagcatca tggcaattgt ctgaccaatg
    18541 ccattgtaga catctgcaac aggaacgaca gaaagtccag ttacacagac cattgacacc
    18601 acgttgaaaa aatgatcgag gtaaaccgta ttaggaccat tgctgtagtg ggtaaaaggc
    18661 atggataaca agagactacc tatcaaaatg acaatcgcaa agctaaaggt tagccgctgg
    18721 gtcaccgata aggacttgaa aaatgagcgt ttcatgattc ctcctaataa tatctcatac
    18781 tatcatatca aaaatacatt aaaaaagcta agcagtaacc tagccttaga ctgaagcagc
    18841 cctgtttaca ataggccctt cctaacatgc tccaaaagac aatagctttt tttgacatgt
    18901 caggcttaag cttttagctc agagcttaaa agtgctgagt aagattttat aaagtcttaa
    18961 gggctttagt cattgttgcc acagtagaaa acagaatggc gagctcactg cctagcctat
    19021 gttttttctt gctaggcttc aaagaggctt gatgttttga agcgtcaaaa gtaatcttga
    19081 cagggttcta tatggctaat cgatatcact caaggctagc acttagcttt tgtggtttga
    19141 tcacatgatc attggctgtg gtcatagcgt cagctccctc ctactagcct ctaatggcta
    19201 ataggaggat caagggcaac aaaaaatgtt cagacagcct ttaatcaagg ctgcctgaag
    19261 cagcattcta tagcctctta caatggtttt tattaggaat accggctttt cgagggtact
    19321 tgtttggcgt ttcctttttc ttttcgacaa gagtgatata gcggccatct ccattaggaa
    19381 gttggtaggg ctggtgatca agcaccttag caaaaagtag ctgaagtgcc tttttagctt
    19441 cttctaattc ttggtccgct gcttgtgcct ttaaagcaat cagttttccc ttgattttta
    19501 aaaaaggaat ggtcaactca gacagaatct gcatgcgggc aacagctcta gcagttacca
    19561 aatcaaattg gccacgaaat tgcttgtctt gtccaaaatc ctctgcccta ccatgataga
    19621 aatgtactcc ctctaatcct agctctttag caaggagctg aagaaaatgt atgcgcttat
    19681 tgagagaatc aataatggta acatcaagct ttggaaacat aattttcata ggaatgcttg
    19741 ggaagcctgc tccagcccca atatctaaca gcctgagagg ctcatttgga atatatccct
    19801 gtaaaagcgg agcaacagag tcataaaagt gcttgagata gacttcattt tcttcagtga
    19861 tggctgttaa gttgatctta cggttccaat caaccaaaag cttaaaataa gtgtcgaatt
    19921 gttctttttg atgatttgtc agagcaaatc ctgcttgctc caggacaagg taaaaggctt
    19981 ggggtgtcat atatatcctc tgtttttaat taattgctac tattttagca taaaatagca
    20041 gaaaactgct gaaaagtccc ttcaatactt gctattaaac tgaaaattgc tataattgag
    20101 acacaaagat taaaggagaa ttacaatgcc aatgttttta gtaatagtag cccttatcgg
    20161 tgtgctggtt gtttggctga tggttagcta taatggcctg gttaaagctc gtatgcatac
    20221 aaaagaagct tggagtcaga ttgacgtgca gctaaagcgt cgcaatgact tgattccaaa
    20281 ccttgttgag acggtcaaag gctatgctaa tcatgaagag aaaaccttag aaaagattac
    20341 tagtcttaga tcacgtgtgg ctgatgctac tacaccgcag gccacaatgg cagcctccaa
    20401 tgaattgagc aagcaggtca ctagcctctt tgcagttgca gagagctatc cagacttaaa
    20461 ggccaatagt aatttcctaa aattgcaaga ggaattaacc aatacagaaa ataaaatttc
    20521 ttattcgcgt caattattta atacaacaac atcgcattat aaccttaagc tagaaagctt
    20581 tccgagcaat cttgtggcta aattgtttgg cttcaagcca agtgagtttt tacaggttcc
    20641 tgaagctgaa aaagaggttc caaaggtaga ctttaccgtc tagtctaatg cggctaatca
    20701 aggtcagaag aggacatcaa tgctttatca acaaatttca caaaataaac gacgaactgt
    20761 tatcctgctt tttgcctttt ttgtcttact ggtagtgatt ggcgctgctg ctgggtattt
    20821 actggctgac agctaccagc tgggggctgc ttttgctctg attattggtg ctatttatgc
    20881 ctttagcatg atttttcagt caaccagcct cgttatggga atgaataagg ctaaggaaat
    20941 cacagtaaac gatgctcctg atttctttca tattgttgag gatatggctc tggttgctca
    21001 gattccaatg ccaagagtat ttatcattga tgatccctca ctaaacgcct ttgccacagg
    21061 ctccagccct caaaatgcag ctgttgcggc aaccactggt ctactaaagg tgatgaatcg
    21121 tgaggagtta gaagcagtga ttgggcatga agtcagccat attcgtaatt atgatattcg
    21181 gatatccact attgcagttg ctttagctag tgctgtcaca ctgatttcca gcattggggg
    21241 gcgtatgatg tggtatagcg gtggcaggag acgtgataac gatcgcaacg ataatggctt
    21301 tggcgctatt atgctgattt tctcaatctt gtcactgatc ttggctcctc ttgcggcctc
    21361 tctggttcaa ttagccattt ctcgtcaaag agagtatctg gcagatgcca gctctgtcgc
    21421 gttaaccaga aatccagagg gcatgattag ggctctacaa aagctaagca attcacagcc
    21481 tatgactcat ccagtagatg atgctagcgc agccttatac atcaatgagc ctagaaaaaa
    21541 agaaaagctt agcgctttat ttagtaccca tccgccgatt gaagatagaa ttgaacgctt
    21601 gaagcatatg tgagagcttg agactagctc agctctcatt tttactagcc ataatgttca
    21661 gaaaacatca ttaattaatt gttttgaccc ggacattttt taagactttt atggaaattt
    21721 gggctatttt cataggggtt ttatggttaa acatttgatt gttggcttgt caatacttat
    21781 ttgtatccag acttaatgtt aaaaaaagtt atgaatttgt cataaagcta ttgacaaatt
    21841 cttgatatca tagtaaaaat agattagagt tttattagga agtgttttat aggagaaagc
    21901 atgttatctg tttcagatat tagaaagcga ccggaaggca ttcgctttga gagagagtac
    21961 gatgttaagg aagcgctgct tatacgtgat ccgcaggtta tagatattaa taacgtcaga
    22021 gcttcgggga gagctcagtt tgatgacggc ttgtatctat tagagtatca gctgggctat
    22081 cagattaccc tgccctcgag ccgttccatg gcgcctgttg tcttagatga gatgcagacg
    22141 gttcaggagc tgtttatcga ggaagcagat gtggcaagta agcaggaaat ggttgatgaa
    22201 aaccttgtct tagtcttatc agaggatcag cttgaccttg aagagagtat tattgacaat
    22261 attttgttgg cgattccctt gcaggtattg acagaggctg aaaaggagtc acaaatcttg
    22321 ccgacagggg aggattgggc agtcttaact gaggagcaat accaggccca gcagaaggaa
    22381 aaagcaaaag acaacagtcc ttttgcgggc ttacagggtc tttttgatga gtaaaaataa
    22441 aaattaaaga tgtctgtatt ttttatttga aaaaagaaca gttgtctggt atactttata
    22501 aatatacggc atattagtca ttttgatgac taaatagcaa tacttgatta atacaaaatg
    22561 gatgaatctt gtacatagct gataaggggc tgtgatacag gaagtaagga ttggtgtaat
    22621 gacaaagaaa attttaatta tcgaagatga aaagaatctt gcaagatttg tttcgcttga
    22681 gctacagcat gagggttacg aggtaaccgt cgaggttaat ggtcgtgagg gcttggagac
    22741 agccctagag aaggactttg acttaatcct tcttgatttg atgcttcctg agatggacgg
    22801 atttgaagtg acacgtcgat tgcaaacaga aaaaacgact tacatcatga tgatgactgc
    22861 gcgtgactct attatggacg ttgtagctgg cttggatcgt ggtgctgacg attacatcgt
    22921 gaagccattt gccattgagg aattgctggc gcgtattcgt gctatcttcc gtcgtcagga
    22981 cattgagtca gagaaaaaga ctcctagtca aggcgtttac cgcgacttag tcttaaaccc
    23041 tcaaaaccgc tctgtcaatc gcggtgatga cgagatttca ctgactaagc gtgaatatga
    23101 cctgcttaat attttgatga caaacatgaa tcgtgtcatg actcgtgagg agctcttgtc
    23161 taacgtttgg aaatatgacg aggctgttga aactaacgtt gttgatgttt atattcgtta
    23221 ccttcgtggg aagatcgata tccctgggaa agagtcttac attcaaactg ttcgtggaat
    23281 gggttatgtg attcgcgaga aataattgat ggcaaagcag aaaaaatata agaaaacgtt
    23341 accaaaacgt ttatcgaatc ttttgttcgt tctcttcttt tgcattttct ctgcctttac
    23401 cctactcgct tatatttcaa caaactactt tttgttgaaa cgagaaaagc aaactatttt
    23461 tcaggctgtt aacattgtta gagttcgtct ctctgaggtg gactctaatt ttacgttaga
    23521 gaatttagca gaggttctct ataaaaatga cagaacgcat ttaaagattg atgacgcaaa
    23581 tggtagtcgt attatcagaa gtgaacgaaa tatcaccaac acgctcaatg ccaatgagga
    23641 tatctatgtc tacaatgttg ataagcaaat gatcttcaca acagatgacg aagaggcctc
    23701 gccaggctta aatggaacta ttggtaaggt aaccaaggac cacattgagg agcaatacaa
    23761 gggcttttca atgactcaga aggtctactc taataagaca gggaagtttg taggctatgt
    23821 tcaggttttc catgacttgg aaaactacta catgatcaga gcacgcctct tcttttggct
    23881 tttggtggtt gagctctttg gggttggtct ggcgtatttc attatcttaa ttgtcacacg
    23941 caacttcttg aagcctctga acaatcttca tgatgtgatg cggacaattt ccaaaaatcc
    24001 agataatctg atgctgcgct cgggtatttc ctcgggtgat gaaattgagg aattgtccgt
    24061 tatttttgat aaaatgcttg ataagattga gacgcataca cgattgcaat caagatttat
    24121 tagtgacgtc agtcatgagc tgcgcacgcc agttgccatt atcaaggggc atattggatt
    24181 attgcagcgc tggggcaagg acgatagtgc tattttagat gaaagcctca ctgcagctgc
    24241 gcaagaggtt gaccgaatgg ctattatgat caatgacatg cttgatatga tccgagtaca
    24301 ggggtccttt gaagggcatc aaaatgatac aactgtttta gagagctcta ttgagaccgt
    24361 tgttggtaat tttagggtcc tgcgtgagga ttttgatttt acctggtact ctgaaaatca
    24421 aagaacccta gccaagattt ataaaaatca ttttgagcag gctctgatga ttttgataga
    24481 taatgcggtc aagtattcta ggaaggaaaa gaaaatcgtc atagaattag cggttaatgc
    24541 tagcaatgaa gctgtggtta aggtcaaaga cagaggtgag gggatctcag aagaggatat
    24601 taagcatatt tttgagcgct tctaccgcac cgataggtcc agaaatcgaa ccagcaccca
    24661 agcaggtctt gggattggct tatccatttt aaagcaaatt gttgatggct atcatttaca
    24721 tatggaggtt gagagtgagc taaataaagg gtcggtcttt attttgcgga ttcccttagc
    24781 tgatcatcaa ggctcatagc tgtatacctg cctgagtatc tagtagatgc tcaggctttt
    24841 gactgttcta atgtgtggtg tgatgatgag gtgtttatca gggaaggagg gctcttggag
    24901 gtaaacctga gtgcttgtct attcttttgt tatccctaaa attatggtaa aatagggtat
    24961 tagattaacg atagaattgg ggtgtttgcg tgcgttgtcc gaaatgtaac tataataagt
    25021 caagtgttgt tgatagtaga caggcagaag atggcaatac gattcgtcgc cgcagagaat
    25081 gcgaaagctg tcacacgcgc tttacaacct ttgagcgctt agaagagctt ccattactag
    25141 tgatcaaaaa ggacgggact agggagcagt tttcaagaga taaaatctta aatggtgttg
    25201 ttcaaagtgc ccaaaagcgt ccggtgtcaa gtactgacat tgaaaatctc atttctcgca
    25261 ttgagcagaa ggttcgtaca gcctatgaaa atgaggtgtc aagtactgtt attggcaatc
    25321 tggtgatgga ggaattagca gagcttgatg agattaccta tgttcgtttt gctagtgtct
    25381 ataaaagctt taaggattta gacgaaatcg aagagctctt acagcagatt actaatcgcg
    25441 ttagaggaaa aaagaagagc agtgtagatg atgaagccta ttgatacctt ttcttatatt
    25501 aagcataatc aggttcaata cgattcaagc agcctgattc agttgtattt tcctattatt
    25561 ggaaatgacg cagtggcagt ttatcagtat ttggttcact tttttgatga tggctcagga
    25621 gcccacaaat ttagtgatat tttaaaccat ctgcagtttg gaatgaagcg cctagaggaa
    25681 gccttggtga tgctgacagc tattgatttg ctggtcttat atcagctgcc agatgcttat
    25741 ttgataaaac tacatcagcc cttgggcagg gaagcctttt taaataaccc aatttatcgt
    25801 aggcttttag agcaaaagat tggagatgta gcggttttgg agttgcaaat ggtgattccg
    25861 aaccaggcta gaaacatctc aaagaccttt tcagatgttt ttggaataga ctctcaggag
    25921 cttaagcagc ctcagccatc aaagataaat tttgatttag atagctttca gcagctaatg
    25981 cggcgtgacg gtcttaggtt tgaggatcat caaaaggacg ttatcagtct ttacagtatt
    26041 tctgagcaat accacctaac ctggtttgac acctatcagc tggctaaggc aacagcagtc
    26101 ggcggcagca ttcgcccaga gcgcatgcta gtcaagaagc agcaagaggg cgctcaaaaa
    26161 acaagtgaat cgttctcacc agctgagcag gttgttctta gagagtctaa gcaggacacg
    26221 cctcttgtct ttttagagaa gatcaaaaaa gctaggcgag ctagagtcac aaaggacgaa
    26281 aaggaattgt tgctgactct agcccgcatg aatttcttgg acgaggtcat caatattatg
    26341 gtattatata ccttcaataa gaccaagtca gctaatcttc acaagactta tctgatgaaa
    26401 atggcaaatg attttgctta ccagcgggtt ttaacagcgg aaactgctat tatcaagaca
    26461 cgcgcctttg gtgagcgtaa gcagcaggca aagtcacagc agtccaatgt gcctaagtgg
    26521 agcaatccgg attatcaaga aaaaacaagt caggaagaac aggcaaagct agagcagttt
    26581 aagcaggctg ccttaaaaag gctggagaac ctaggaaaga gtggtgacta gatggaaaag
    26641 atcgggaaaa tggtagagca tttgggacag gctagtcgtg tagctagtgc tgagctgatt
    26701 gaggctatac ttgctgatca ggaggtggct gagtttatca aggctcacca gctatctcag
    26761 gcagaaataa agctgagttt atcaaagttc aaccagtttt tagttgagcg ccggaaatac
    26821 cagacaggtg atgagaccta tattgctaag ggctatcagc ccattttggt catgaacgag
    26881 ggctatgcag atgtgtctta cctagagaca agagagcttg ttgaagccca aaggcaggca
    26941 gctattgcag atcggattca tttggttagt ctgccaagat cttatcgtag ggtttctttg
    27001 tcagctgttg atgttaacaa tgccagtcgt atgcaggtgt tttcagagct tttggatttt
    27061 gttgagcagt atccagcggc agagcaaaag ggtctctacc tttatggcga tatgggggtc
    27121 gggaaatcct atctgatggc tgctatggca catgaattgt ctgaaaaaaa gggtgtatca
    27181 acaactcttc ttcattttcc tagctttacg attgatgtta aaaatgccat ttcaaatggc
    27241 tctgtcaaag aagagattga tgccatcaag catgtccctg ttttaatttt agatgatatt
    27301 ggtgcagagc aggcgacctc atgggtgcgt gatgaggtgc tacaggttat tttgcagcat
    27361 cgtatgctag aggatttgcc aacctttttc acctctaatt acagctttgc agatttggag
    27421 agaaaatggg caaagatcaa aggaaatgat gagacctggc aggccaagcg tgttatggag
    27481 cgtgtgcgtt atttagcacg tgaatgccat ttagaagggg ttaatcgccg ccagggctag
    27541 ctaaacgcta gctcaagcga tggataatga gataaagaaa aggagaatca tggttttacc
    27601 tacagttgcc attgttggac gtcctaatgt tggaaagtcc acgttattta accgaattgc
    27661 aggagagcgt atttctatag ttgaagacgt cgaaggggtt actcgcgacc gcatttacac
    27721 gactggtgag tggcttaacc gccaattttc attgattgac acaggtggta ttgatgacgt
    27781 tgatgctccc tttatggagc aaatcaagca tcaggctcat attgcgatgg acgaggcaga
    27841 tgttattgtc tttgtggttt ctggtaaaga gggcgttact gatgcagacg aatatgtctc
    27901 taagctcttg tatcgtacca acaagccagt gattttggtt gtcaacaagg tggacaatcc
    27961 agagatgcga aacgatattt atgattttta ttctcttggc ttaggagatt ccttcccggt
    28021 atcatcagtt catggtattg gtacgggtga tgttttagat gctatcattg ataacctgcc
    28081 gatagaagag ccagtagaaa acgacgatgt gattcgcttt agcctaattg gacgtccaaa
    28141 tgttggaaaa tcaagcctca ttaatgcgat cctaggagaa gagcgtgtca ttgccagtcc
    28201 tgttgctggt acgactcgtg atgcgattga tacaagcttt accgatgaat ccggtcaagc
    28261 ctataccatg attgataccg caggaatgcg taagtccggc aaggtctatg aaaatactga
    28321 aaaatactca gtgatgcgtg ccatgcgtgc cattgaccga tcagatattg tgttaatggt
    28381 tattaatgcc gaggagggca ttcgtgacta tgataagcgg attgcaggct ttgcgcatga
    28441 ggcaggtaag ggcatgatta tcgttgttaa taagtgggac accatcgaaa aggataatca
    28501 tacagtagct aggtgggagg ctgatattcg tgatcaattt caatttttga cctacgcccc
    28561 tattatcttt gtttctgccg ttacaaagca gcgcttaaac aggcttcctg agttgattaa
    28621 gcgtatcagt gatagtcaaa gccagcggat ctcgtcagct attttaaacg atgtgattat
    28681 ggatgctatt gcgatcaacc caaccccaac ggataaggga cggcgtctaa agattttcta
    28741 tgctacacag gtttctgtga agccgccaac ctttgttgtt tttgtgaatg aagaagagct
    28801 gatgcacttc tcttatctgc gctttctaga aaaccagatt cgtgctgctt tcacctttga
    28861 agggacacca atcaagctga ttgcgcgcaa tcgcaaataa gcccttttat tactcttgtt
    28921 agtattggaa gcagcgagtg ctgttgatgt gcggtgtcta gaccttgtgt gtcaggactt
    28981 ttgaccgacc aataagcctt accagaaatg agaggctgct atccaaatag agcttaccag
    29041 caagcaaggc gtgccaagca ttgatgtcac atgataatca ttagccctag gctagtgatt
    29101 ttttagtgct ttaaagccta tcagaacagc tatatacagc tactcaaata tgttttaata
    29161 gcctttaaga gagatttttg caggaaatct aagctgaagt ttgttataat caaaggataa
    29221 gcaaaaaggt gggagcagat atggctagat taattccggg gcggattcgc aatcaaggca
    29281 tcgagcttta tgagcaaggc ttggtgaaaa tcatagatga caggactgac cttcttcgag
    29341 cagaggtgga tacttatcag gttcaatatg gtatcaatga tgaggatatt aggtgtcagt
    29401 gtgattattt tgagcgaaag cagtattgcc agcacattgc ggctctagaa tattttctga
    29461 aaaataatca gaagggcaag tcgctctcag agcagcttaa caaccagctg gaaagtaagg
    29521 aggaaactaa aaagctgacc tcctttggta gtcttttttt ggacagtttg cacatgaacg
    29581 aggacgacac gaccaaatat aggcttttag cttctggtgc taaaagtcct ttctcatctg
    29641 attactggtg gagccttaag ataaatcgct tgcccggaga gaaggcttat gttatccgcg
    29701 atatcaaggc ctttattcat ttggtcaaag ttgagggctt ttaccagatt ggaaagaatt
    29761 actttgagtc tctttccata ttgcagtttg atcaggctag tcaggagctg attcgttttc
    29821 tttggcgttt atcaacgcat tcagataagt tagattacga atggctattt cctaaccacg
    29881 ctcgtcatct tcggttaccg gcaggctttt ttgaggaggg cattgacctg ctgacggggc
    29941 tttacgagtt ttcatttgag acctcctctc aaacctattc tcatctttat gttcgacctc
    30001 tggaggcaga ggctggtctc tttcagttta cagttgatgt tcatcgcagc tctattgagc
    30061 tttacattaa ggaaaaaaat atagagtatt ttttcaataa tgaatacctg ctatacatga
    30121 acacctttta ccacctgagc ctgaagcagc aaaaaatggt tcaagctatt cgcagcctgc
    30181 ctattgaggc cgatttggcc aagcacattc attttgatct tgatgatcag gctaagctgg
    30241 cagctagctt gctggaattt cgagagcttg gtcaggtgaa ggctcctaaa agctttgata
    30301 ttagagattt ccaagtgact tttgtctttg atattactga aaaaggtgag ttgacctctc
    30361 agctgatttt tgactatggg agcattcaga tcagtgataa ggcaagctta gaccagctcc
    30421 cctttgctag ccattataaa aaagaaagca gtatttatcg tgccttgaag cgctttgggc
    30481 tttctccgca gttttttgct aagaaagcct tgactgaccc caaggactgg tatcgctttt
    30541 ttacagaagc tgttccttat tttgaaagtc taggtagggt tcagctttcc tctaagctcc
    30601 aagatcagcg cttaatggaa agccctcagc ttacagtcaa acgtgaggga ggtcttttag
    30661 atatttcctt tgatttttca acggtttgtc agactgatat tgaaaaggct ttggccactt
    30721 tgtttagtga tcgctcttat tttgtcaatc agtcaggcaa gctggtcgtt tttgatgaag
    30781 agacacaaaa aatcagccgt agcttacagg aactaagagc taagcagctg gcaaatggtc
    30841 acctccagct agaaggaata gctgccaccc agctgtctca tctattttcg gatctgtctt
    30901 ctgttcattt ttctgaggag ctagagaccc taatcaagga cctgcagcac ccggatcgct
    30961 ttgagctggg agagctggcc gttaaggcca aggtgagaga ttatcagctg cagggcatca
    31021 aatggctctc tgtgcttgat aagtatggct ttggtggtat cttggcagat gatatgggct
    31081 tgggcaagac actgcaaatc attgcctttt tatcaagcag gctaaccgag acctccaagg
    31141 tgcttatctt ggcaccctct agcttgattt acaattggtt agatgagttt agtaaatttg
    31201 cccctcagat agatgctgct gtatcctacg ggctaaagcc ggcacgagat gctcttattc
    31261 aagaaggaca tcaggtgacg attaccagct attcttcctt taggcaagat ttagaaacct
    31321 atcaggcaaa tgattatgat tatttaatct tagatgaggc gcagatgatt aaaaatgccc
    31381 agaccaagat tgctcagagc ctgcgtgcct ttgacgtgaa gaattgcttt gctttatctg
    31441 gtacgccgat tgaaaataag ctgcttgaaa tctggtccat ttttcaaatt gttctgccag
    31501 gcctgctgcc atctaaaaaa gcctttttga aaatggaggc cagagacgtt tctcgctata
    31561 ttaagccctt tgtcatgcga cgcaaaaaag aggaggtctt gccagagcta ccagaattaa
    31621 tcgagatgaa ttattacaat gagatgtccg atggtcaaaa agcgatttat ctggcacagc
    31681 taaggcagat gcaggagcgg ctgtctgctg caactgatga tgatattaat cgcagtaagc
    31741 tggaaatcct gtctggtatc acacgtctaa ggcaaatctg tgatactcct agcctgttta
    31801 tggattatca aggaggaagc ggtaagctag acaatctaag aaccttgctg ctgcaaatta
    31861 aagaaaacgg tcatagggct ttgctgtttt cacaatttaa gggcatgctg gctcttgtca
    31921 agcaggaaat ggatcagctt ggcttatcat cttataccat aacaggctca acaccggcca
    31981 atgaccgtca agaaatgaca cgtgccttca ataatggctc aaaggacgcc tttttgattt
    32041 ccttaaaggc cggtggtgtt ggactcaatt taacaggtgc tgatactgtt attttgattg
    32101 atctatggtg gaacccagct gtagaaatgc aggccattag tcgtgctcat cgtattggtc
    32161 aggaggacaa tgtagaggtt taccggttga ttacccgcgg aacaattgag gaaaaaatac
    32221 tggagcttca ggaaaataag cgtcatctga ttaccactgt tttagatggc aaacaaggcc
    32281 tagcaagcat gtctgtcgag gagatcaaag aaatccttgg tcttcagccc tagcatgtat
    32341 ggcttttagc acacgctctt aagcctatca gctaaaggct agtgtctgtt ctctataaca
    32401 aataaggcaa gagaatagag gtgatgagct agtcacatca tttttgcttt gctgcctttc
    32461 tttttaggaa ttactttgaa aaataggatt atttagttta taatagggaa tgctatagga
    32521 aggagagtga gatagaatga caaagcatgc gtttcctctg gttgcagatg gtgagcctat
    32581 tattgagtca gctaggcaga tggctttata tgaaaacgaa gatttgatca caaatattgc
    32641 tggcagctat caagataaac attacgacga catcataaga gaccatcaat ttgctgagaa
    32701 gactcctgtc gtctctaaag gatcccttca tcattctcca gttgtcgatg aagatcatag
    32761 ctacgctcaa aaggccagaa ggcaagcaaa gcaggatgtc aaagaaaaaa gacaggctta
    32821 tattgctaaa aatatggctt atagcccaaa gcaggcaagc aagaaaggtc aaagtggggc
    32881 cttctcttct aaaaaaccag cgacagaatt gagccgtttt acagagaaat taaaccaaga
    32941 gtcttatatt ttagctgagc ttcctcgtca atataaggag ccgcaaaata ccagccaagc
    33001 agctgtcaaa aaaaataatt atgacttttt gaagcgcagc caaatctaca atcatcaaga
    33061 agacagagat catcgtgaaa agaccattgc tcaagagcta aacctgagtc gctttgaaga
    33121 tattaagtaa gctttataca gccttatgtc tgtcaacatt aaaaggagtt aacatgtcaa
    33181 aaacctatca ttttatcgga attaaaggat ctggaatgag tgccttagcc ctgctgctcc
    33241 atcaaatggg gcataaggtt caaggcagtg atgtggagaa gtattatttc acacaaagag
    33301 gcctagagca agcaggcatt accattttgc cctttagcga agataatatt tctccggata
    33361 tggagctgat agcaggtaat gcttttcgtg aggacaacaa tagcgaggtt gcttatgcga
    33421 tgcgtcatca gctgcccttt aaacgctacc atgagttttt aggtgagttt atgaagcagt
    33481 ttactagtct tggtgtagcc ggtgctcatg ggaaaacctc taccacaggc ttgttgtcac
    33541 atgtgctcaa gcacatgacg gctacttctt atttgattgg tgatggtact gggcatgggg
    33601 ctgccgatgc tcgttatttt gtgtttgaat cagatgagta cgagcgtcac tttatgcctt
    33661 atcacccgga atattctatt atcactaata ttgattttga tcaccctgat tattttacag
    33721 gccttgatga tgtgttcaat gcctttaatg actatgctaa gcaggtgaaa aaggctcttt
    33781 ttgtttacgg tgaagatgag gaattaagaa agattagctc tcctgcaccg atttactatt
    33841 atggctttga ggacactgat gatttcgtag cctttgatat cacacgcacg acaaatggct
    33901 cagactttaa ggtaaagcac aagggtcatg ctattggtca gtttcatgtt ccagcctatg
    33961 ggcgtcacaa tattttaaat gctactgcgg tgattgctaa tttatttatt gcaggctttg
    34021 atatgaagct tgttgcagag catctgaaga gcttttcagg ggtgaagcgt cgttttactg
    34081 aaaaggtgat caatgacact attattattg atgactttgc tcatcaccca acagaaatca
    34141 ttgcaacgct tgatgctgct aggcaaaaat accctaataa ggaaatcatc gctatttttc
    34201 agccacacac ctttacaagg accattgctt tgctagatga ctttgcccat gccctaaatg
    34261 aggctgacag tgtttatcta gcgcctatct acggctcagc gcgtgaggtt gataagggtg
    34321 atgtcaaggt ggaggatcta gcggctaggg ttgagcgccc agccaaggtc atctcagttg
    34381 acaatgtatc gccgctgctg gatcatgata atgcagtcta tgtttttatg ggagcaggtg
    34441 atattcagtt gtatgaacgc tcgtttgaag agctgctggc taacttaact aaaaataatc
    34501 aatgattaag cgacctgcct taggcaggtt ttctcgtcgt aaaggaggac ctatgctaat
    34561 tagacatgtg aatcagactg actgggagat tattgctgat atcgaacagg ccaatttttc
    34621 tccccaagag gctgtagcag ccaatgtgat aaaagagcgt gcagagctta tttcggatac
    34681 ctttcttgtg gctgttatcg ccaatcagtt tgtcggctat atcgaaggac ctgtcattgc
    34741 tgagccaagg cttgaggatc acctatttca tggtgtgacc aagaatccag caagaggtgg
    34801 ctatatagcc attaccagtc tttctgttgc tcctggatac caaaagcagg ggattggcac
    34861 agctctctta gctgcaatga aggatttagc agttgcacag gatcggctgg gtatcatact
    34921 tacctgtcat gactatttga ttccttacta tgagatgaat ggttttcaag atcaaggcct
    34981 gtcagcttca aagcatggtg gctctgtttg gtatcaaatg ctatggcagc cataggaagg
    35041 ctattaaagc ttagcatgta ttaagaatta gtaacaaaag ggggatttta ttgcatttat
    35101 agtgcaatta ggatataatg gcggttgatt aagtttagga ggaatggctt tgactgattt
    35161 taaagatgat gagcaaagac gtcagcagca aaaaagcttc aaagaaaaga ttctagccga
    35221 attagaaaaa gcaaatcaga ttagaaaaga aaaagaagaa gagcttttta aaaaggatct
    35281 agaggttcaa gaggctgcta gaagaacagc tcagctttat gcagaatata aaagacaaga
    35341 agcactaagc aataacccca aacaagcgtc tgatatagca gctgcgtcgc aagagacgac
    35401 ctcaacggct tcaacagccc acacctctgc gattaagcta gaagagacag cagtagctac
    35461 tggggatcaa gcattgtcgc caccagagga gcctgcattg agtgaaagcc tgcttaagga
    35521 agaggcaagt gtcgaaggtc agactaagaa gggtggtcca gtgagaagaa aaacaagtaa
    35581 gcgccagcag acagatcgaa tggccaaaaa aatttcgaca gtactgatat cgtcgattgt
    35641 cgctattatt gtggtgattg gcctcgcagg gacagcctat gtgtatagtg cccttaaccc
    35701 tgttgacaaa aatagcgatg actttgttca ggttgaaatc ccagccggct caggcaataa
    35761 gcttattggg cagatccttg aaaaagaggg gctgatcaaa aatagtaccg tctttagctt
    35821 ttacactaag tttaaaaatt tcactaattt tcaaagtggc tactacaacc tacaaaagag
    35881 catgagccta gaagacattg cccaggcctt acaagagggt ggcacagcag agcctacaaa
    35941 gccagtacta ggaaaaattt taattccaga gggctatacc attaagcaaa ttgctaaggc
    36001 catagaaact aatagtaggg caaagaatcg tagcaaggct aaaacaccat ttcactcaaa
    36061 ggatttcttg aatttggtga caagtgatgc ctttattcaa gagatggcta aaaaatatcc
    36121 gaaattgcta ggagatcttc caagcaagga agtagctact tatcagctag aaggctacct
    36181 tttccctgcg acctataatt attataagga aacaacacta aaagaccttg cagaggaaat
    36241 gattgcagcg gcaaatgcaa acctagcgcc ttattatgag gcgattgcag ctagtggcaa
    36301 gacagttaat gaggtgctga ctttggcctc cttagttgaa aaggaaggct ctactgatga
    36361 cgatcggcgt caaattgcca gcgtatttta caatcgctta aataatggca tggccttaca
    36421 gtctaacatt gctatattgt atgcaatggg taaattggga gaaaagacaa ccttagcaga
    36481 ggacgctgct attgacacaa ccattaattc tccttataat gtttatatca atactggctt
    36541 aatgcctggt ccagttgata gtccagggct tgcagctatt gaggcgacta tcaatccagc
    36601 ggcaacagat tacgtttatt ttgtagccga tgtgcgtact ggtgaggttt attatgcaaa
    36661 aacatttgaa gagcactctg caaatgttga aaaatatgtt aacagtcaaa ttcagtaagg
    36721 acaaacatgg tgctttagca tcatgtttgt gtttctgatt cgtcaaaaga aaaaggaaaa
    36781 gagaaagata atggcagaaa agacttatcc aatgacagca gcagaaaaag aacagcttga
    36841 aaaggaatta gaagagctaa aattagttcg tcgtccagag gttgttgagc gcataaaaat
    36901 cgctcgttcg tatggagacc tttctgaaaa ctctgaatac gatgctgcta aagatgagca
    36961 ggcttttgtt gagggacaaa tctcaacctt ggagacaaag attcgctatg ctgagattat
    37021 tgatagcgat gctgttgcca aggacgaggt ggcgattggt aagacagttg ttgtccagga
    37081 ggttggcaca caaacaacag acacttatca tattgtcggt gcggcaggag cagatatttt
    37141 ttctggaaag atttcaaacg agagtccaat tgcacaggcc ttgattggta agaaaacagg
    37201 agataaggtt aagattgagt ctccagcagc tacctatgag gttactatca tcagcgttga
    37261 caaaacacaa taagacttat ctgactatca gtgcagtgtc ctgatagtct ttttagtggc
    37321 ttgcttttta atatcagttg ttgtggtcta ttaaaaagag ctgcacttta gaaagtttta
    37381 actaagatac tttatgacct agtctcatac attaaaaaag cgaacaggtc taattttcgg
    37441 aatccctgaa aattagacct gttcgtttgt tttatcttga gtcagacttt tgtcacagac
    37501 tcttttagct atcttagcga cgcttttttt gtttaccggc gtttcggttt aacttagtcc
    37561 tcttgcttgt gctaagggct tgcttttcag ctgtaacgtc cttgcgtggc tggtgagatt
    37621 tataggcctt aggagggttc tttgcgaact cctctgcaat ttgcttgcgg agccttggtt
    37681 ttaaaaggta ggttgtgatc aattgctgaa tgatactaaa gaaaccacca actagccaat
    37741 acaagcctaa tccggcaggc aggtaaaacg acatgacaat catcataatt ggcatggtgt
    37801 acagcatggc tttcatttgt tcacgttgct cctcagggac tgccatcatt gacagccagg
    37861 attgaacgaa gtataaagcc gcaattacag ctgtaagcaa gacgctgcga tgccccaggt
    37921 caatgcccat aaaggtactt gttgagactc ccttggtaaa ttggaccgca acatacatgg
    37981 cagaaaagaa aggcatttga atcagcagtg gcaaacagcc tataccgcct agcgggttga
    38041 ctccattttc acgctgggcc gccattaatt ctgtttgggc tgccattttt tcttcagtgc
    38101 ttgtagcgtt tttgatgcgt tgattaattg gctcaaaaaa aggctttagg taggccattt
    38161 tttctgattg gtagcttgcc ttccatgatt ggtagagccc aagtggtagg ataatcgttc
    38221 taacaataat agttacaaca atgatggcaa gaccatagcc tagggcggtg ctgttagcaa
    38281 agtaatcaat gagaaaggaa acgggctttc caaggtaatc ccaaatgatg ccctccgggt
    38341 gccccttggc gtctctgccg acacaccctg tcaatgtcag taggaccgat aaggcaagtc
    38401 ctgagaaaag tatgcgattc gttttgagtt tcaatgtgtt tgtcctttaa tttttaatat
    38461 acctaaccat tttactgttt ttttgagaaa ttaacaatag ttctacagta ggatttttaa
    38521 ttgctgatcc taaaatcatg gaaatcctca aagtgagatg gattaacatc aacataggtc
    38581 acctttgccc atttagaagg tccttttctg atttcctgga taaagcgcgt catctttgca
    38641 gggtcactag cctgtgctaa aatctcaaca gtcccatcac tattgttcca cacgcggccg
    38701 taaatatcac caatttccaa agctagtgcg taggttgaat agcgaaagcc aacaccctgc
    38761 accctgcctg aaacgattag tctgaccttt ttcataagtc acctcttttc tttttattat
    38821 agcatagata gcttataaat actaaaagtt gtcatggagc aggcagccaa aggataggca
    38881 aagactgcaa gtgggctatc tgctgaggta aacaataggt cttagtgcag caaggctatg
    38941 tttatggtta gctctccttc ttgtcttcta aaaaggaaag ctaatgggct tacgacacct
    39001 gataagggga gaaagctcct tttaggctga tagccttctg atggttttta tgcaaaagag
    39061 tgaacaattt tgtgatataa taagaccatg attatcacat caaaagcaaa ccatttgatt
    39121 aagcaggcta agaaattact gcaaaaaaag catcgcaagc actcttactt gattgagggc
    39181 tggcacctat ttgaggaggc tcagagatct gggcaggaat tgatacatat ttttgttctg
    39241 gaggaaatgg cagagcgctt atcaggcttt gatcaggttg tcatcgtcag tccagagatt
    39301 ctaaaggagc tgacgagctc tcccaatcca cagggcatta ttgctgaggt taagctttgt
    39361 caacaggcct taccgactag ctatgctgga aaatatttga ttttagagga cattcaggat
    39421 ccaggcaatc tagggacaat cattagaaca gcggacgcag caaagtttga tggggtgttt
    39481 ttgtctgaga agtctgcgga tgtctacaat caaaaaactc tacgctccat gcagggcagt
    39541 cattttcacc tgccgatttg gcgaacggat atttatcagg tcagtcaggt gatgcagcag
    39601 caaaaaatac cagtgctagc aacgaccttg tctcaggatt cgattgatta caaggacctc
    39661 tcagctagga gcagccttgc ccttgtttta ggaaatgaag gtcagggcat tagtcctgag
    39721 atggcagctt tggctgatca gctgattcat attagcatgc ctggacaagc tgaaagctta
    39781 aatgttgcag ttgcagcagg aatcctcatt ttcagcctaa tttaagctag tatggtataa
    39841 taatgatgtg aggtgattag tgtatgcatt atacagaaga tacagaatac atggagcatg
    39901 ttggtcattt gattgctcac cctcgctttc aaaggcttgg agatattgtt cagcatcacc
    39961 attctactcg cttagagcac tctgtcaatg tttcttattc tagctatagg ctggcaaaga
    40021 ggcttggctt agacgccaag agtaccgcac gaggtggctt gctacacgat ttcttttatt
    40081 atgattggcg agtaaccaag tttaacaagg gacacgcttg ggtgcaccct agaattgctg
    40141 ttcgaaatgc taaaaaatta acagcactca acaaaaaaga agaggatatt atcctaaagc
    40201 atatgtgggg agctactatt gcttttcctc gctataagga aagctatatt gttacctttg
    40261 ttgataaata ttgggcggtc aaggaggcca tgacgccgct gcgtcaaaaa tggacgaacc
    40321 gtcgcttcct gcgtcgaaag acgcttcaaa gtcacaatca ttaagtaaaa aaaggagtta
    40381 tgatgaacga taatgttatt tacacacagt ctgacgcagg cttgagccat ttttttgcca
    40441 aggtctatag cctggttggt atgggagttg ggctttctgc ctttgtttct tatttgatgc
    40501 tgtttccatt taggcaaaat ttagtctcga ttgttcttga tcatcctatg gtctattatg
    40561 gggcggctat tgttgagctt gtactggttt ttgttgctag tggtgctgca cgtcgcaata
    40621 caccagcagc tttaccctta tttcttgtct attcagcctt aaatggcttt accttgagct
    40681 tcattattgc agcttatgcg caaacaacgg tgctacaggc ctttatctca tcggcagctg
    40741 ttttctttgc tatgtcactg cttggtgtta aggttaagcg tgatctgtca ggtattcgaa
    40801 aggccatgtt tgcagccttg attgggatta tcgtggctag tctggtaaat ctctttatcg
    40861 gtagtgacct gatgagctat gtgatcagcc ttatttcagt gttgatcttt tctggcttga
    40921 ttgcttcaga caatcagatg atcaagcagg tctaccaagc ctctaacggt caggttggtg
    40981 acggctgggc tgtcgctatg gctcttagct tatacctaga ctttatcaac ctctttatca
    41041 gtctacttcg tctcttggga agaaatgact aatagctatt ttaagcgcag ctgctgattg
    41101 tcacttaatc gctattacga gaaatcagcg aagctgcagg tgttaccttt tgttagaaaa
    41161 gagtggctgc tgctagtaag aaagtagctg ctaggagagc ctgatgagcg tgactgtcaa
    41221 ggaaggccag ttactattgc taccatctag ggaaggtacc aaaaaaagtc aagaagcggg
    41281 cccaagggct cgtttttgtt tgcttgattt gtggtaaagt gcttcaaacc aagcctatat
    41341 ctagtctgat agctcttatc agctgacaac atcatattta caatgcctgt tggtgtagat
    41401 ttgtaaagca tgctcttttt tggtataatg agaggaacaa aaaatcgagg agaatatcta
    41461 tcaatatgtc tacagctatc tggatattat taatcattgt tgctcttaca gccggtcttt
    41521 ttggtgggat ttttattgcc cgcaagcaaa ttgaaaagga aattggagag cacccacgat
    41581 taacgcctga ggccattcgt gaaatgatga gtcaaatggg tcaaaaacca agtgaagcga
    41641 aaattcaaca aacttaccgc aacattgtca agcaatcaaa agccgcaatg actaagggta
    41701 aaaaataggt tacggattag aaatcgtggt ttctaagcaa tagctaagag tgaacagtct
    41761 ttgatgttaa aagcttgttt agagcttgca ttgtcagtta gaggtgtcaa ctgttcaggg
    41821 gttaacaata gactcagttg gctcttacca gctgagtttt ttatgcttca atgaggaaat
    41881 aatcgttatg gacaatagac caattggttt tttagattct ggtgtaggag gcttaactgt
    41941 tgttagtgag ctgatgcgtc agcttcccca tgaaaaaatc atttatattg gtgattcagc
    42001 aagagctcct tatggtccta gacctgctga acaaatcaga gaatatacct gggagttggt
    42061 tcgtttttta ttaacgaaac atgtcaagat gattgtcttt gcttgtaaca ctgcaacagc
    42121 tgttgcttgg gaggaggtca aggaggcttt ggatattcct gttttgggcg ttatcctgcc
    42181 gggcgctagc gcagctatca aggctactag tggaggaaag gttggtgtta ttggcacatc
    42241 aatgactatt tcttcaggca tttaccagga aaagatccag ttgctggctc ccactgttca
    42301 ggtaactagc ctagcctgtc ctagatttgt tcctattgtg gagtccaatg agataagctc
    42361 aagtgtggcc aagaaaattg tctatgaaac cttggctccc ttagttggaa agatagatac
    42421 ccttgttttg ggctgcaccc attatcctct tcttaggacg attatccaaa atgtgctggg
    42481 accacaggtt aaattgattg atagtggggc agagtgtgtg cgtgatattt ctgttctttt
    42541 aaattatttt gagattaatg gcagtcgaga tgatgaacat aggcgtcatc atttttacac
    42601 tacagccggc tcagacagct ttcaagcaat tgcctcagcc tggctaaatc aaacgataga
    42661 tgtggagcat gtgaccttat gagtgataac atttatgaat acaaggataa agacaattgg
    42721 tttattggca agatgacagg ccataattta atggctggct ggggggttaa ccatgagctt
    42781 attgccaaaa tagacgatat gttaggtgcg attgctggtg atgtggattg ggaaagtccg
    42841 gtcggttatg atgtgactgt tattcgttac gcctcccctt ttgccttgat tagctttgtt
    42901 gttggcatga tcaatcagaa agccaatcga gcccttaagg ttgttcggca ctcaggtgcg
    42961 attttagtga ccgaaaacga gcgattgctt gctgtgcata tgccagatga tggcgtccct
    43021 gtggctgact tctttggtca acaggcagat ggctttgggg atacgatttt gattgcgact
    43081 cgaaatgaag gcaagaccaa ggaatttcgc cggctttttg gtgatatggg atatcgcgtt
    43141 gaaaatctca atgattaccc agagcttcca gatgtggcag aaaccggggt cacctttgag
    43201 gaaaatgccc gcctaaaagc agaaaccatt tcaaggctta ctggaaagat ggttctggca
    43261 gatgattcag ggctcaaggt ggatatttta ggtggcttac ctggggtctg gtcagctcgt
    43321 ttttcgggcc ctgatgctac tgatgagact aataatgcta agctattgca tgagctggca
    43381 atggtatttg atcaaaagga tcgctctgct caatttcata cgaccttggt ggttgctgca
    43441 cctggtaaag acagcttggt tgtcgaggct gattggcatg gctatattgc aaccaagcca
    43501 aaaggcgagc atggctttgg ctatgatccc ttgtttatcg ttggggagac tggacgtcat
    43561 gcagcagagc tagctgctga tgaaaaaaac aagctgtctc ataggggaca ggcggtcaag
    43621 aggttaatgg aggtatttcc agcatggcaa gcaaaacaat cattgtgatg agcgattcgc
    43681 atggcgatcg tgaggttgtg gcagctatta aaggccgtta ccttggaaag gttgatgcca
    43741 ttttccataa tggcgattct gagctagaaa gctcagatcc tatttgggag gggattcatg
    43801 ttgtggcagg caactgtgac catgatagcg gctataagga tagcctagtc acctcctttg
    43861 atggcttgac tattgctcaa acacatgggc atttgtatca tattaacttt acttgggata
    43921 ggctagatta ttttgctcag gagactggag cggatatttg tttgtatggg cacttgcaca
    43981 gacctgctgc ttggcaattg ggcaagactg tctttatcaa tcctggctcg gtcgctcagc
    44041 cgcgtggtga ggtgaatgaa aagctgtacg cgcgtgttga atggacagca gcttgcatta
    44101 gggtggatta ctttacctgt cagcataagt cttacccatc actttctaag gaatttaaac
    44161 gatgatagca aaagaatttg aagccttttt aatcagtcat ttggatagct acctgattcc
    44221 agcagaggag ctagccattt ttatcaacac gcataatgct gatcatgtca tgctcttatt
    44281 ggttagcaat ggtttttcac gagttcctgt cattaccaag gaaaagcaat atgtcggaac
    44341 gatcagcatt tctgatataa tgacctatca agccaaaagg cagctaacag actgggagat
    44401 gacgcaaact aatattggcg acatggtcaa tacaaagatt gagaccatca atattacctc
    44461 tagcttgact gaaatcatgc ataaattggt tgattttccc tttttaccag ttgttaatga
    44521 tgacaatcga tttatcggta ttattacgcg taagtccatt ttgaaggcgg ttaatagcct
    44581 tttgcatgac ttcactgatg aatacacaat cacaaaaaaa tgatagcatt tattgaaccc
    44641 tttctagcaa gcaaatctct tgctaataac agccagcaat cctatcgcta tgatttaagg
    44701 cagttttgcc agcaggtcgg acagcgtatt aatcctgaaa ccctagccct ctatcagcaa
    44761 agcttgtctg gccttacggt agcagctaaa aagcgcaagc tttcaacggt caatcagttt
    44821 ttgtactatt tgtaccagca gaaggctttg acagactatt ttaaaatgga cgataggata
    44881 gaagcctctt tttctttgaa gccccagctg acaaggcttg acaccagcgc tttttatgct
    44941 gaaacagcct tcctaaaagg gcagctcatt gcgctgctga ttctggagct gggcttgacg
    45001 ccaagtgaga tagcagggct tcgtcttgct gattttgacc tgggtcttca ggtgctaagg
    45061 ttgcaatctc acagaggcat tcgtgtgatg accttatcaa aggccttgct gccatttttg
    45121 gaaaaggcaa cagaagctca gcagctctac ctctttgatc atgacgccaa gcccttttca
    45181 aggcaatggt tttttaacca gctcagagat tttttagaga gcattggctg tgcggagctt
    45241 tcagcccaga gtctgagaga gcaattcatt ttaaatgaaa aagcagccgg taaatccatc
    45301 attgaggtgg ctcagctgct ggggctaaaa agcccgatca ccttagaaaa atattataag
    45361 atgtaatgga tataaaagta aaagattttg aaggtcctct tgatttactc ttgcacctag
    45421 tgtcaaagta tgaggttgat gtttaccagg tgcctattgt ggaggtcatt gaacaatact
    45481 tggcctatat tgagaccctg caggcgatgc gcttggagct tgctggagag tacatgctga
    45541 tggctagtca gctgatgctc atcaaaagca gacgactgct gccaaagctg gtagacaagg
    45601 agcctgatga ggaggatctt gagcaagagc ttttgggtaa gattgaagaa tatagtcgtt
    45661 tcaaggctct gagtcaggag ttggccagcc agcatgacaa gagggctctg cttttttcca
    45721 agccaaagca ggagcttatc tttgagcagg ccgtcctaca aaaggataaa acagtcatgg
    45781 atttgttttt agctttttca cagttaatgg ctgcaaagca agaggccttt aaatataacc
    45841 atacggttat tgagcgagat gattatcgta ttgaggatat gatggagctt attgaagcta
    45901 ggcttgagct agagcaggag cttactttga cggatttatt gaagcattgt gatcatctca
    45961 atgaggccat taccttgttt ttagcaagcc tagaattaat caaacggcag cttgttggta
    46021 ttgagcagac atcacatttt ggccagattg ttttgcgaaa ggagatccaa tgacctattt
    46081 atctcagctg gaggccttgc tgtttgtcgc aggagaagaa ggactaagcc tacgtcagtt
    46141 ggccagccta ttagagttaa caccgacagc cttacagcag cagctcgaca agctttctca
    46201 gaaatacaaa gaggataagg aatctggcct gtgcttgatt gagtcctcta ggacctataa
    46261 gttagtcacc aaagagtgtc tggctccctt gcttaaagac tatgctaagg ctccaatcaa
    46321 ccaaaccttg tcacgagcaa gcctggaggt tttgtcaatt gttgcctata agcagccgat
    46381 tactcggatt gaaattgacg agattcgtgg tgtcaattca agtggtgccc ttagtaaatt
    46441 agtggccttt ggtttggttc aagaggctgg caaaaaggaa gtgattggtc gaccaaatct
    46501 ttatgcaaca acagattact ttcttgatta tatgggtatc aatcatttag aagagctggt
    46561 tgatatttct tctattgctg ttgaagagca agagacaacc ctgttttaaa ggcaaagagg
    46621 agcttgtctc atttgcagat aggccttatg ccctctacta gaagagataa cagtcctaac
    46681 aaggtatagt gcctgaaaat cctattgtcg ttatggacag cggtcttttt aggcatgcta
    46741 ttaataagag tagacctgtt taagctagtg agcttttacc cataggagag tgactggtct
    46801 gttggagcta tcatcagatt tcctaataag aaagagagaa ggataatgag aattaacaaa
    46861 tacatcgccc atgcaggcct tgctagccgt cgtaaggctg aagagctgat caagcgaggg
    46921 ctggtgaccc taaatggtca ggtgataaca gatttagcaa ctactgttaa atcaggcgac
    46981 cttgttgagg tagaggggat tcctatttac aatgaagaga aggtttatta tctcctcaac
    47041 aagcctcgtg gtgtcatctc aagcgtttca gatgataagg ggcgtcagac agtgattgat
    47101 ttgctgccgc aggttaagga gcgcatttac cctgttggtc gcttggactg ggatacctct
    47161 ggcttattaa ttttgaccaa tgatggtgat tttacagata aaatgattca cccccgtaat
    47221 gaaatcgaca aggtttatct ggctcgtgtc aagggagtgg taactaaaga aagcctgcgt
    47281 cccttaacac gtggtgtcgt tattgatggt aaaaaaacaa agccggctcg ttaccgcatt
    47341 attcgtgttg agcctgataa aaatcgctct attgttgaac taaccattca tgagggccgt
    47401 catcatcagg tcaagaaaat gtttgaagtg gttggacact tggttgataa gctatcaagg
    47461 acacagtttg gcagccttga tgtcagaggc ctaaagcccg gagaagccag aaggctgagc
    47521 aaaaaagaag tcagccagct acatcattta gcgagcacac gaaaatgatc aaagccctac
    47581 tcattgctcc tgtcagagcc tatcagaaat atatttctcc cttatttcct ccttcctgtc
    47641 gttatcagcc gacctgctcg gcctatatga ttacagctat tgaaaagcat ggtgctaagg
    47701 gtgttttgat gggacttacc agactattaa ggtgccaccc ttttgccgct ggcggagaag
    47761 acccggttcc agataccttt tccttaaaaa gacatttcat aacgcatgaa aaaatacagg
    47821 attttgacca aaaaactgat tgacaatagc agttaaagtg ctataatagc agttaagtat
    47881 tcgttggttt aaatcaaacc tgttatgatt taagttagcg agtcaccgtc aaccacattg
    47941 tttgctgagc atgactccgg gcagtgtggt ttttttgatg aaaagagtaa gcgggacaag
    48001 catgaaacaa gaaatcatta atagacaata tagggaaaaa gatagtcaaa accatgtggt
    48061 gctctttcag ccacaaattc cacaaaacac aggaaatatt gctaggacct gtgctgccac
    48121 caacacgcct ttacatatca tcaggcctat gggctttccg attgatgacc gtaagatgaa
    48181 aagagcgggg ctagattatt gggataagct agacattaga ttttatgatc atctagatga
    48241 atttttagca caatgtgatg ggagcttgca tgtgattagc aaatttgctg atagggtata
    48301 ctcagatgaa gcctacaatg atcgtcagtc tcattatttt ttgtttgggc gtgaggatac
    48361 tggtctgcct gagcccttta tgcgtcaata tgctgatagg gcactcagga ttcctatgaa
    48421 tgatgagcat gtcagaagtc tcaatgtctc taatgctgtt tgcatgatcg tctatgaggc
    48481 acttagacag caagccttta agggcttaga gcttagccat acctatgagc atgacaaact
    48541 aaaatcataa taagcatatc gcaaaacatc agttagattg aagaagtatc cgtaggggag
    48601 cttcttcagt ctttttttat tgtattcttt gcttattaac caagcagttg acacgaaaat
    48661 tccaatagat cgtttaaagc caataaaacc attattaggc ttgcattaca ggcaggtatc
    48721 aaagaaagat atagaaaaat ataccagaaa aaaatctcat aaaagtgtca aaatagtaaa
    48781 aaatcgccaa aaatatgtca atattatacc attattatag tataatattt ataatcatat
    48841 tataatatta aaatatctgg tgtctagctg tttttgtaaa agcaaaaaac ctgcaccacc
    48901 ttatgataaa gcataaagga atataagcat gatagtctac ctaaagcaac acaaaaatta
    48961 ctggaaatta gtcagcatag cagctttaat cattatttta ggaggaatac taacaatgaa
    49021 ttggcttaat ggggataggg acaataaagg cgagaataac tactatcaag tagagaagga
    49081 tttagcaatg gaaattgtta gtgagtttga aggagtaaaa gagattagct ttcttagtcc
    49141 agtacaatcc aaagaaacag ggtattgggg aacaacagct actataaata aaactaatga
    49201 gatatcttat tctttttcga tgactttttc aggaaagctt gatgattatt cttactatta
    49261 cgataaatgt tttaaattag tgaagcgtca caaaaaattg acattaagtc aagtggatct
    49321 aacagatatt gatattaaat attctaaggg agggaaataa atgataactg acaaaaacta
    49381 taactggcta gctggaaaag tatatgatgt tgatgctaat aaagtaacta ttcctgttag
    49441 aaaaaatacg gatattctta atcgttatgt caaagtcctt gaagccgaag acaatcctga
    49501 caacggtatg cagtttacgg tgtcaaagag taataggaat gttctagctt taaattataa
    49561 actaaggagc ttctatgaca gtaaaaaaga aagtcatcat tttattagga atggtagcaa
    49621 ttttagtaat gggaggtata tttatgttta gctataatca gaatcaagcg aaaatgttag
    49681 aacgacaatt taaccatgaa caaaaacgaa ttgtcttgta tttgttaaat cattatagcg
    49741 gaattaatga gatagaattt aatgatattg aaaacaacag tacaacaggt tctaagaatg
    49801 tattgctgac aataaataat aaaattaaaa tggaagttac attttttaat ttaaatgatg
    49861 atacagataa ctatgttatt agttggaatg ggaaattaag tttgatagac aaaaatccta
    49921 taactcattt aagttcaata gataaaataa aagtaaaata ttggagtaac aatgatagta
    49981 acagataaaa attataatga tatagccgat ggggtttata aggttgatgc tggcaaagtt
    50041 attagacctt ggcgaaacgg taagactttt aaaactaacg ggaaagatta ccgcgtcctc
    50101 aaaacagaag acaaccccga caatggtatg caggctattg ctgtagctcc gattaagggt
    50161 agtgaggtgg gtaagagtca tatcatgatt gtttatgtaa aaagcagcta ttggctagcg
    50221 tcctagcaat aaaaggagtt gatgatgaaa aagcaacaaa gcaaacgacg gaaactaatt
    50281 ggcatagtgg ctttaataac aattttagga ggaatactaa caatgaattg gtttaatgac
    50341 gaaaaactaa atagagagcg tagagaacaa gagagggcag ctatttattt tagtaataca
    50401 tatgaaaata tacataaaat aaagatcatc ggtatagata aaaatttaaa aacaggttct
    50461 atgaataaag ctacaattgt taatagtaag tactatatat ccgtaacgtt tatgggaggt
    50521 gagatttata caggtgtaga gcaagcttca aaagacaatg aggaattttt aaatcgtcga
    50581 aaaaaagcag agaataagac aaccttgagt aaggacattg aagttattta taaggagaaa
    50641 tagtagtggt tagtgataaa gattataata aactctctga aaaagtatat gatgttgatg
    50701 ctaataaagt aactatttct gttagaaaaa atacggatat tcttaatcgt tatgtcaaaa
    50761 tcctcaaagc cgaagatacc cccgacaatg gtatgcaagc tatggctgtt gt
//
LOCUS       DARYYD010000008        50719 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.008, whole genome shotgun sequence.
ACCESSION   DARYYD010000008 DARYYD010000000
VERSION     DARYYD010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 50719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50719
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.008"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            175..963
                     /locus_tag="TV188_000393"
     CDS             175..963
                     /locus_tag="TV188_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1533784.1"
                     /translation="MARGRGRLTPQEIEALGFFSSKFNDLLNETNTKQVELSKATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADYFGLMKSDIDPRFAPRKKNHELKIPTSPLVKKIT
                     TTVVELNVPRKQKVLDFATDQLKEQKNKMTSMEKKLYEYKVYEKLSAGTGYGYFGDGN
                     YDTVFYEEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGVYAVEWDGQTYIK
                     KVYREKDGLRLVSLNKKYKDKFAPFSEDPRIIGKIVGNFMPKEY"
     gene            972..2141
                     /locus_tag="TV188_000394"
     CDS             972..2141
                     /locus_tag="TV188_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HEL1533785.1"
                     /translation="MGLFNFGKIKDVALEKKLQKLQQKIENEKEKLREIKEEIALAND
                     TLDLQEYGFFERQYKFSHSTKYKDALDTLRMKQKTLIKNGEATSIISPMTLDGSAAKG
                     KAMQNQLRKAAIRGFNGEADALLVKVSVVNVDKKVQTLQKAFEQLNKMYERNLIQLTF
                     KYLDLKAQELRLAAEYELQKQEEKEILREQRAREREDKKLQAEITAKRKQLEKDRKHF
                     LQMVKNVEVMLANASPKEQEKLQLQLIEYQNKLSELDKIEEDIDYREGHATAGYVYVI
                     SNIGAFGEDVYKIGVTRRLDPMDRIRELGSASVPFTFDVHALIFSEEAFALESELHNK
                     FEAYKVNKINSRKEYFRVPFAKIKEVLENHKELAIEITEEAEAFEYRQSILKNGG"
     gene            2144..2347
                     /locus_tag="TV188_000395"
     CDS             2144..2347
                     /locus_tag="TV188_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533786.1"
                     /translation="MKWLFLILFIGCGANAVNLSKKVNSDDEVDENNSHLISHSNEEI
                     PWNKKEQLYWGTASIVFLVLFII"
     gene            2479..3912
                     /locus_tag="TV188_000396"
     CDS             2479..3912
                     /locus_tag="TV188_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014570823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEL1533787.1"
                     /translation="MITTRKVAIYVRVSTTNQAEEGYSIQGQIDSLIKYCEAMGWIIY
                     EEYTDAGFSGGKIDRPAMSKLITDAKHKRFDTILVYKLDRLSRSVRDTLYLVKDVFNQ
                     NNIHFVSLQENIDTSSAMGNLFLTLLSAIAEFEREQITERMTMGKIGRAKSGKTMAWT
                     YTPFGYDYNKEKGELILDPAKAPIVKMIYTDYLKGMSIQKIVDKLNKMDYNGKDCTWF
                     PHGVKHLLDNPVYYGMTRYNNKLFPGNHQPIITKELFDKTQRERQRRRLGIEENHYTI
                     PFQAKYMLSKFLRCRQCGSRMGLELGRPRKKEGKRSKKYYCLNSRPKRTASCDTPLYD
                     AETLEDYVLHEIAKIQKDPSIASRQKHIEDHELKYKRERIEANINKTVNQLSKLNNLY
                     LNDLITLEDLKTQTNTLIAKKRLLENELDKTCDNDDELDRQETIADFLALPDVWTMDY
                     EGQKYAVELLVQRVKVDRDNIDIHWTF"
     gene            complement(3942..5110)
                     /locus_tag="TV188_000397"
                     /pseudo
     CDS             complement(3942..5110)
                     /locus_tag="TV188_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623352.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            5166..5807
                     /locus_tag="TV188_000398"
     CDS             5166..5807
                     /locus_tag="TV188_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEL1533788.1"
                     /translation="MEDYKTIMTDGLFEESIKKSRFICQIKRVYTEEEARAFIADIKK
                     KHYKANHSCSAMIIGDKGQTKRSSDDGEPSGTAGIPMLSVLERQELTNLVAVVTRYFG
                     GVKLGAGGLIRAYSGVTAAAIQALKVVEVKKQTGLAISLTYPQYQIYPNFLEQEALIE
                     MNTEFSDVVRTAIYFDPERLESISKALIEHYHGKVSFEEIESQRIEVPVLPAN"
     gene            5928..6854
                     /gene="cysK"
                     /locus_tag="TV188_000399"
     CDS             5928..6854
                     /gene="cysK"
                     /locus_tag="TV188_000399"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003063544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEL1533789.1"
                     /translation="MSKLYHNITELVGKTPIIKLRNTSPEEAADIYVKLEAFNPGSSV
                     KDRIALAMIEAAEKAGMIKPGDTIVEPTSGNTGIGLSWVGAAKGYRVLIVMPETMSIE
                     RRQIIQAYGAELVLTPGSDGMKGAIAKAEEIARETGAWMPSQFDNPANPKVHEETTGQ
                     EIIAVFGEKGLDAFVSGVGTGGTISGVAHALKAVNPDISIYAVEADESAVLSGEESSP
                     HKIQGISAGFIPNTLDTKAYDHIIRVASEAALATARSIGAKEGFLVGISSGAAVYAAI
                     QAAKELGKGKKVLAILPDNGERYLSTALYQFD"
     gene            complement(7241..7603)
                     /locus_tag="TV188_000400"
     CDS             complement(7241..7603)
                     /locus_tag="TV188_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEL1533790.1"
                     /translation="MKIGDKLHGTITGIKPYGAFVALENGTTGLIHISEIKTGFIDNI
                     HQILRLGEAVLVQVIDYDEYSHKVSLSLRTLEEEKHHVSSHHRFSNSRYKIGFKPLEA
                     SLPNWIEEGLDHFKQEKS"
     gene            complement(7603..9003)
                     /locus_tag="TV188_000401"
     CDS             complement(7603..9003)
                     /locus_tag="TV188_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1533791.1"
                     /translation="MDAKLKYKAKKIKMVFFDIDDTLRVKNTGYMPESIQRVFKELKK
                     KGILTGIASGRARYGVPKEVQDLQADYCVKLNGAYVKDNQKNIIFQAPIPADTVVAYK
                     KWANAVGIDYGMAGRHEAVLSARNEMISDAIDKVYSTLEVCPDYNEHHDVYQMWTFED
                     KGDDLQLPVELAEQLRLVRWHDHSSDVVLKGTSKALGVSKVVEHLGLRPENILVFGDE
                     LNDLELFDYAGISIAMGVSHPQLQEKADFITKTVEENGILYALEELGLIDKELHFPQL
                     DLAGHEGPRVVMKTNHGELTLALFPEHAPKTVANFLGLAKEGYYNGVIFHRIIADFMI
                     QGGDPTGTGMGGQSIYGQSFEDEFSEELYNLRGALSMANAGPNTNGSQFFIVQNTSLP
                     YSQKELERGGWPKDIAAAYAEHGGTPYLDRRHTVFGQLADEASYQVLDNIAAVETGAQ
                     DKPKEDVVIEAIEVFD"
     gene            complement(9036..9677)
                     /locus_tag="TV188_000402"
     CDS             complement(9036..9677)
                     /locus_tag="TV188_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1533792.1"
                     /translation="MSNITVILVDDHEMVRMGLKSFLNLQQDVDVIGEASNGREGVEL
                     ALELRPDVVVMDLVMPELGGVEATLEILSKWKEARVLVLTSYLDNEKIYPVIDAGAKG
                     YMLKTSSAAEILNAIRKVAKGELAIETEVDKKIKAHDQQPNLHEELTAREYDILHLLA
                     KGYDNQTIADELFISLKTVKTHVSNILAKLQVDDRTQAVVYAFRHHLVPQDDH"
     gene            complement(9670..10674)
                     /locus_tag="TV188_000403"
     CDS             complement(9670..10674)
                     /locus_tag="TV188_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1533793.1"
                     /translation="MKKRYYALVWLYSTITILSIVFVVMDNLGITFDYLRSHLWQLER
                     LVFSVVLLIISVTLLLLLLWIILDDNSKRSINKNLRRILNNQRIHLEETSEINTNLTR
                     LSAKMSHITTNIQKKENAYILDSQKIVQQERKRIARDLHDTVSQELFASSMILSGVSM
                     SLDQMDKEQLQQQLVTVEAMLQNAQNDLRILLLHLRPTELANRSLSEGFTMILKELTD
                     KSGIEVVYKENIGTLPKAIEDNLFRIAQEFISNTLKHAKASRLEVYLNQTPTELQLKM
                     VDNGVGFDMGQVRELSYGLKNIEDRVNDLAGTLRLISQKGKGVSMDIRLPLVMGDEDE
                     "
     gene            complement(10671..11363)
                     /locus_tag="TV188_000404"
     CDS             complement(10671..11363)
                     /locus_tag="TV188_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEL1533794.1"
                     /translation="MKKFQFFLLVECMLLAMGIMTILANDLSSFILILVLILLALRFY
                     NQDTRNSFLLTVSLLLLFLIFMLNPYIIMAVLLGIVYVIINHFSQVKKKNRFALIRFA
                     EEKMTVRQVKNQWLGAANYESDYYSFEDINIIRASGNDTIDLTNVIVTGMDNVIIIRK
                     IFGNTKILVPIDVAVTLEVSSIYASVDFFELQEYDLRNESITLGEAEDSSLKKVKIIV
                     STIAGNVEVARR"
     gene            complement(11496..13391)
                     /gene="pknB"
                     /locus_tag="TV188_000405"
     CDS             complement(11496..13391)
                     /gene="pknB"
                     /locus_tag="TV188_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEL1533795.1"
                     /translation="MIQIGKLFAGRYRILKSIGRGGMADVYLANDLILDNEDVAIKVL
                     RTNYQTDQVAVARFQREARAMAELNHPNIVAIRDIGEEDGQQFLVMEYVDGSDLKKYI
                     QDHAPLSNNEVVRIMEEVLSAMTLAHQKGIVHRDLKPQNILLTKSSVVKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSIIDENPNVPQALENVVIRATAKKLSDRYRSTFEMSRDLMTALSYN
                     RSRERKVVFDDVESTKPLPKVTPTPVTAPKVSNASQASAAVDARLEQTSQMDTLQKPQ
                     KKKKNGRFLGTLLKILFSFFVVGVALFAYLVLTKPTTVKVPDVTGSSLNAAKQVLEEA
                     GLKVGKVHQIESDTVSEDQVVKTNPQAGSAKRKGSSVDLYLSIGNKGFEMENYKGQDY
                     QDVMTSLTETYGVPKSKIKIERIVTNEYPENTVISQSPSAGEKFNPAGKSKITLSVAV
                     GDTVIMPMVTEYSYADAVNTLTALGIDAARIKAYVPSSSSPTGFVQVSSPSSKAVVSG
                     QTPYYGTQISLSEKGDISLYLYPEETRASSSSSSSDTSAPNPSAGDTTDSSSHTELGQ
                     NDAVTTP"
     gene            complement(13388..14128)
                     /locus_tag="TV188_000406"
     CDS             complement(13388..14128)
                     /locus_tag="TV188_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEL1533796.1"
                     /translation="MKISLKTDIGQKRSNNQDFINKFDNKKGITLVILADGMGGHRAG
                     NIASEMTVTDLGREWVKTDFTELSQIKDWLLTTIEAENQRIYDLGQSEDYKGMGTTVE
                     AVALVDSNAIYAHIGDSRIGLVHEGNYSLLTSDHSLVNALVKAGQITEEEAASHPQKN
                     IITQSIGQASPVEPDLGVKVLEKGDYLVINSDGLTNMIANEEIVDILCQDISLDEKNQ
                     ALIDLANQRGGLDNITVALVHKESGEAE"
     gene            complement(14166..15488)
                     /gene="rsmB"
                     /locus_tag="TV188_000407"
     CDS             complement(14166..15488)
                     /gene="rsmB"
                     /locus_tag="TV188_000407"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003060995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEL1533797.1"
                     /translation="MANDWKKSARGQALLIVEDIFDHGAYSNLALKHQLANQFLSDKD
                     KALVTEIVYGTISRKITLEWYLAHYIEDRDRLDKWVYYLLMLSLYQLAYLDKVPAHAI
                     VNDAVNLAKARAHGRGADKLVNAVLRQLTNKPLPDIKSIKRKNKYYAVAYSVPVWLVK
                     KLIDQFGEERAVAIMESLFVRSRASIRVTDLTKLDEIKQATGSEQSLLARTGLTKRAG
                     NFAASSYFINGDITIQDETSQLVAPTLDIQGQEMILDACSAPGGKTAHIASYLTSGKV
                     VALDLYEHKLALVNENAKRLGVADRIETKVLDAREVHKHFAKNSFDKILVDAPCSGIG
                     LIRRKPDIKYNKEGQDFQQLQEIQLEILSSVCQTLRKGGIITYSTCTIFDEENFQVID
                     KFLQRHPNFEQVTLKHAQADIVKDGCLMITPEQYQTDGFFIGQVRRVL"
     gene            complement(15478..16413)
                     /locus_tag="TV188_000408"
     CDS             complement(15478..16413)
                     /locus_tag="TV188_000408"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEL1533798.1"
                     /translation="MTRLIFMGTPQFSATVLQGLLEKPAYDILAVVTQPDRAVGRKKD
                     ITMTPVKKLALAHQLPVFQPEKLSGSQELADIMALGADGIVTAAFGQFLPTVLLDSVT
                     FAVNVHASLLPKYRGGAPIHYAIINGDKEAGVTIMEMVKEMDAGDMISSASLPILDTD
                     NVGTMFDKLAILGRDLLLKTLPDYLSGDLKPVPQDHSQATFSPNLSAEEERLDWSKPA
                     REVFNHIRGMNPWPVAHTLLDGQRFKIYEAELAEGSGSAGQIIAKTKKALVVAAGEGA
                     LSLTLVQPAGKPKMPIVDFLNGIGRSLEVGDVLGE"
     gene            complement(16480..18864)
                     /locus_tag="TV188_000409"
     CDS             complement(16480..18864)
                     /locus_tag="TV188_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEL1533799.1"
                     /translation="MQHIAQVIVDIPLMQTDKPFSYLIPDELLSLVKIGSRVHVPFGN
                     GNRLLQGFVIGFSSQSTQQLKAIWSVLDAEPVLNQEQVALAEQLRQTVFSYKITLLKA
                     MLPSLLNSHYDRLLTPTADLAAADLADVFSNGDSLLYSKLSPEQEGRVLRLIQSGKIR
                     ATYLAKDKKTIKTETYYQVNRLALQEHKISNRAKKRQALKAYLLANPQKDKLAKLYQD
                     YSREVVSYFVTNQLIELEERRVNRSEDYFNHIKAAPLLKLNQQQQQAVDQITKAVGRE
                     AKPFLLEGITGSGKTEVYLHVIAHVLEQGKTAIVLVPEISLTPQMTSRFISRFGRQVA
                     IMHSGLSDGEKFDEWQKIKTGQARVVVGARSAIFSPLENIGAIIIDEEHEATYKQESN
                     PRYHARDVALIRARHHKAALVMGSATPSIDSRARASKGLYQFIQLTERANPLASMPQV
                     EIVDFRDYIGQQEVSSFTPYLIDKLKERLARKEQAVLMLNRRGYSSFIMCRDCGYVDQ
                     CPNCDISLTLHMDTKTMNCHYCGFQRAIPKLCPSCQGKSIRYYGTGTQKAYDELKQVL
                     PEARILRMDVDTTRKKGSHEAILSQFGNGDADVLLGTQMIAKGLDFPNVTLVGVLNAD
                     TSLHLPDFRASERTFQLLTQVAGRAGRADKPGEVLIQTYNPEHYAIQLAKKQDFEAFY
                     AYEMGIRRKLGYPPYYFTVGLTLSHKSEQEVVKKAYQLLTILKQGLSDQIRILGPTPK
                     PIARTHNLYHYQIILKYRFEDQLEATLNQILDWSQEQDNRELKVIIDQEPQSFM"
     gene            complement(18928..19245)
                     /locus_tag="TV188_000410"
     CDS             complement(18928..19245)
                     /locus_tag="TV188_000410"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEL1533800.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILQAKRAHELEAGAAPTQSFKSV
                     KSTLQALEEIESGNVVIHPDPAAKRAAVRARIEAERLAREEEERKIKEQIAKEKEEEG
                     EKI"
     gene            complement(19270..19896)
                     /gene="gmk"
                     /locus_tag="TV188_000411"
     CDS             complement(19270..19896)
                     /gene="gmk"
                     /locus_tag="TV188_000411"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEL1533801.1"
                     /translation="MSERGLLIVFSGPSGVGKGTVRQEIFSTPDHKFEYSVSMTTRPQ
                     RPGEVDGVDYFFRTREEFEELIKNGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKAKVPDGVFIFLTPPDLDELQDRLVGRGTDSQEVIAKRIERAKEEIALM
                     REYDYAVVNDEVPLAAERVKRIIETEHFRVERVIGRYDQMIKTTKSLR"
     gene            complement(20058..21668)
                     /locus_tag="TV188_000412"
     CDS             complement(20058..21668)
                     /locus_tag="TV188_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEL1533802.1"
                     /translation="MLINIITLLVCGLIGVILGYALISIRLKSAKEAAELTLLNAEQD
                     AVDIRGKAKADAAHIKKTAQRESKASRKELLLEAKEEARKYREEIEQEFKSERQELKQ
                     LETRLAERALTLDRKDENLSSKEKVLDSKEQSLTDKSKHIDERQAQVEKLEEDKRAEL
                     QRVAAMTIAEAREVILMETENKLTHEIATRIRDAERDIKDRTDKTAKDLLAQAMQRMA
                     GEYVTEQTITSVHLPDDNMKGRIIGREGRNIRTLESLTGIDVIIDDTPEVVVLSGFDP
                     IRREIARMTLESLIADGRIHPARIEELVEKNRLEMDNRIREYGEAAAYEIGAPNLHPD
                     LIKIMGRLQFRTSFGQNVLRHSVEVGKLAGILAGELGENVALARRAGFLHDMGKAIDR
                     EVEGSHVEIGMEFARKYKEHPVVVNTIASHHGDVEPDSVIAVLVAAADALSSARPGAR
                     NESVENYIKRLRDLEEIATSFDGVQSSFALQAGREIRIMVQPEKISDDEIVVLSHKVR
                     EKIENNLDYPGNIKVTVIRELRAIDYAK"
     gene            21825..22310
                     /locus_tag="TV188_000413"
     CDS             21825..22310
                     /locus_tag="TV188_000413"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEL1533803.1"
                     /translation="MPKEVIVESFELDHTIVKAPYVRLISEEFGPQGDVITNFDVRLV
                     QPNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKI
                     ITSSLEEIATSITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVT
                     S"
     gene            complement(22455..23906)
                     /locus_tag="TV188_000414"
     CDS             complement(22455..23906)
                     /locus_tag="TV188_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533804.1"
                     /translation="MSEKSKAFESEAESQNLELHEAKKMTIGEAVRKDSELKAGITED
                     DSVLDKYIKRHRNEVSSQKFDAKYMELDTASLDNFIKKQREELSKAGLVDVEPVDEAS
                     TEEKPAGETSFIEPLAARADTSAAATDSASDFTGQLADDAVSERPAEVESILSDSYAS
                     RRSKKKKPLFAILLATLTLVASAFALNHIYQLSKHKPQSKATVSKKARSKASTANQTN
                     KTKANAKAFEDLYKTFFTDNDKTTLKNSAFDQLPNLETALKRLEGTAYYDKAKEKVTG
                     LKKQVTAIQAVNGKFTTAAIVNGEKIAAEVKADANFDDLASDTLTTGNAKLDSLLQSS
                     IKAGREQLASRSATQAASTPAASALPASPAAPEVPAVPAPVAPMYGITGYDPSILQRD
                     LSRVPYNQAMIADTGNPAWAFNPGVLERIVATSQARGYISGNDYILEPVNIINGNGYY
                     NMFKPDGTYLFSLNCKTGYFVGNGKGHAEDLDY"
     gene            complement(23920..25074)
                     /locus_tag="TV188_000415"
     CDS             complement(23920..25074)
                     /locus_tag="TV188_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEL1533805.1"
                     /translation="MKEQFTLVATAAAGLEAVVGKELRALGFDCRVDNGKVFFEGDIE
                     AIAKANLWLRAADRIKIIVGQFPARSFEELFQGVFALDWEHYLPLGARFPIAKAKCVR
                     STLHNEPSVQAITKKAIVRKLQQHFHRPEHIPLQEVGAEFKIEVSILKDQATLMIDTS
                     GSSLFKRGYRVEKGGAPIKENMAAAILKLSNWFPDKPLVDPTCGSGTFCIEAALIGMN
                     IAPGFNRSFAFEEWSWVDKDRVQKVRDAAEKEANYDIELDISGFDIDGRMVELAKRNA
                     EEAGLADIITFKQMRLQDFRTDKINGVIISNPPYGERLLDDKAVDILYNEMVQVFAPL
                     VTWSKFILTSDDHFEQKYGQKADKKRKLYNGTLRVDLYQFYGERVKRNLI"
     gene            complement(25138..25506)
                     /gene="rnpB"
                     /locus_tag="TV188_000416"
     ncRNA           complement(25138..25506)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="TV188_000416"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(25519..25842)
                     /gene="gpsB"
                     /locus_tag="TV188_000417"
     CDS             complement(25519..25842)
                     /gene="gpsB"
                     /locus_tag="TV188_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEL1533806.1"
                     /translation="MTGIIYSPKDIFEQEFKTSMRGFDKKEVDEFLDNVIKDYEYFNA
                     QIEALKAENEALKKAKAQVRDPLAGSSQAVSQPTRVAQSATNFDMLKRISKLEKEVFG
                     KQIIE"
     gene            complement(25964..26479)
                     /locus_tag="TV188_000418"
     CDS             complement(25964..26479)
                     /locus_tag="TV188_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEL1533807.1"
                     /translation="MTAILVTGYRSFELGIFSEKDKRVAIIKKAIERDLIAYLEEGVD
                     WFIFTGNLGFEQWALEVANDLKKTYPLKTATIFAFETHGSTWNDRNQQQLQQFRETDF
                     VKYSYPSYESPKQLKSYHHFLIHNTDGAYLFYDSEHETRLSYLVAAMKEQPCYPLSFL
                     NFERLNDIADE"
     gene            26555..27163
                     /gene="recU"
                     /locus_tag="TV188_000419"
     CDS             26555..27163
                     /gene="recU"
                     /locus_tag="TV188_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEL1533808.1"
                     /translation="MVNYPHNPIRQKVTPLQKQQKHKQVDFANRGMSFEASINATNAY
                     YLAKGIAVIHKKPTPIQIVKVDYPRRSRAKIVEAYFKQASTTDYSGIYKGHYIDFEAK
                     ETRQKTAMPMKNFHAHQIEHMAAVLKQKGICFVLLHFATLKETYYLPAKALIDFYQID
                     RGNKSMPLDYIRKNGFEVKLGAFPQVPYLDIIEQKFLGGDYN"
     gene            27150..29315
                     /locus_tag="TV188_000420"
     CDS             27150..29315
                     /locus_tag="TV188_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1533809.1"
                     /translation="MITINNPKILKFLKYTLGAILSLIIVTITLGGLLFAYYISSAPK
                     LSEAQLKSTNSSLVYDGNNHLIADLGSEKRENVTADSIPINLVNAIISIEDKRFFNHR
                     GVDLYRILGAAFHNLTSKTTQGGSTLDQQLIKLAYFSTNESDQTLKRKAQEVWLALQM
                     ERKYTKQEILTFYINKVYMGNGNYGMLTAAKAYYGKDLKDLSYAQLALLAGIPQAPSQ
                     YDPYTQPETAQSRRNIVLQQMYAEKNITKAEYEAAIATPISEGLQPLQQRASYPKYMD
                     NYLKQVIEQVKAETNKDIFTSGLKVYTNIIPEAQKKLYDIYNSEDYVYYPDADFQVAS
                     TVIDVTNGHVIAQLGGRNQDTNVSFGTNQAVLTDRDWGSTMKPITDYGPAIESGAYNS
                     TAQTTNDSVYYWPGTHTQLYNWDRRYYGWMTIQAALMQSRNVPAVRALEAAGLSYAQS
                     FLSDLGINYPEMHYSNAISSNNSSSDSKYGASSEKMAAAYAAFANGGLYYKPQYVNKI
                     EFSDGTSKVIENKGKRAMKETTAYMMTDMLKTVLTYGTGTAAAIPGVAQAGKTGTSNY
                     TDEELAQIVETHGLSPDYVGTMAPDENFVGYTNRYAMAVWTGYKNRMTPIYGYSLEIA
                     SHVYRNMISYLTGGYSDDWTMPSGLYRSGGFLYLSGTYTNSSDYTSSVYNNLYGNNSS
                     ASSQSSDEDTTEDSHSEANDSTTSSSEQQSSSTDDKKTN"
     gene            complement(29358..30692)
                     /gene="pepC"
                     /locus_tag="TV188_000421"
     CDS             complement(29358..30692)
                     /gene="pepC"
                     /locus_tag="TV188_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEL1533810.1"
                     /translation="MSVLTETFTEQLYANYEANAKYLALENAITHNGLLKSLETRQSE
                     IDNDFVFSIDLTKDKVSNQKASGRCWMFAALNTFRHKLISEFKLEDFELSQAHTFFWD
                     KYEKSNWFMEQVIATADQALTSRRVKFLLDVPQQDGGQWDMVVALFEKYGVVPKSVYP
                     ESVSSSNSRELNQYLNKLLRQDAQILRDVISAGADHQAVQAKKEELLQEIFNFLAMNL
                     GLPPRQFDFAYRDKDNHYHADKGITPQAFYEKYVGLKLSDYVSVINAPTADKPYGKSY
                     TVDMLGNVVGSPEVRYLNLDMERFKELAIKQMQAGESVWFGSDVGQVSDRQKGILALN
                     TYDFQAGMDIQLSQDKAGRLDYSESLMTHAMVLTGVDLDDTGKPIKWKVENSWGDKVG
                     DKGYFVASDAWMDEYTYQIVVRKDLLTADELAAYEAEPQVLAPWDPMGALAK"
     gene            complement(31381..32205)
                     /gene="nadE"
                     /locus_tag="TV188_000422"
     CDS             complement(31381..32205)
                     /gene="nadE"
                     /locus_tag="TV188_000422"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEL1533811.1"
                     /translation="MTLQEDIIRQLEVKAVIDPKQEIRQSVDFLKAYLLKHPFLKTYV
                     LGISGGQDSSLAGKLAQMAIEELRAETGDEQYQFIAVRLPYGVQADEADAQKALAFIQ
                     PDQALTVNIKEAVDGQLRALEAAGLEISDFNKGNIKARQRMISQYAIAGQTAGAVIGT
                     DHAAENVTGFFTKFGDGGADILPLFRLTKRQGKALLKVLKADPSLYEKVPTADLEDKK
                     PGLADEVALGVTYQEIDDYLEGHTISAEAQARIEDWWHKGQHKRHLPITIFDDFWK"
     gene            complement(32202..33662)
                     /locus_tag="TV188_000423"
     CDS             complement(32202..33662)
                     /locus_tag="TV188_000423"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEL1533812.1"
                     /translation="MYRDDSLTLHTDLYQLNMMQVYFEQGIHNRNAVFEVYFRREPFN
                     NGYAVFAGLQRIVEYLEQLTFSETDLAYLKELGYSPAFLTYLRELRLELTIRSAQEGD
                     LVFANEPIVQVEGPLGQCQLVETALLNIVNFQTLIATKAARIRSVIEDEPLLEFGTRR
                     AQEMDAAVWGTRAAIIGGADATSNVRAGKRFDIPVSGTHAHALVQAYGNDYDAFKAYA
                     SVHKDCIFLVDTYDTLRVGVPTAIRVAKELGDKINFLGVRLDSGDLAYLSKRVRQQLD
                     AAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVSIE
                     QADGTMRDTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITFTGVNVNDLEEIHM
                     FHPTYTYINKTVRDFDAVPLLVDIFDKGKLVYQLPSLKDIKAYARKEFDKLWDEYKRV
                     LNPQHYPVDLALDVWQNKMHLIDKIRKEACKRSDLI"
     gene            complement(33938..35332)
                     /locus_tag="TV188_000424"
     CDS             complement(33938..35332)
                     /locus_tag="TV188_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1533813.1"
                     /translation="MSTKEAKSTKELENGMVRGLQNRHVQLIAIAGTIGTGLFLGAGR
                     SIALTGPSIIFVYMITGVFMFLMMRAIGEMLYYDPDQHTFINFITKYIGPGWGYFSGL
                     SYWISLIFIGMAEITAVASYVQFWFPAWPSWLIQLVFLVLLSSINLIAVRVFGETEFW
                     FAMIKIVAILALIATAVFMVLTGFETHVGHASLANIVDHFSLFPNGKLKFFMAFQMVF
                     FAYQAIEFVGITTSETANPRKVLPKAIQEIPMRIVIFYVGALVSIMAIVPWYQLPTDE
                     SPFVMVFKLIGIKWAAALINFVVLTSAASALNSTLYSTGRHLYQIANETPNALTKALR
                     INTLSRQGVPSRAIIASAVAVGVSALINILPGVADAFSLITASSSGVYIAIYALTMLA
                     HWKYRQSSDFMPDGYLMPSYQLTTPLTLAFFAFVFISLFLQKSTYIGAIGASIWILVF
                     GCYSQLKCKKALKG"
     gene            complement(35452..36369)
                     /gene="trxB"
                     /locus_tag="TV188_000425"
     CDS             complement(35452..36369)
                     /gene="trxB"
                     /locus_tag="TV188_000425"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEL1533814.1"
                     /translation="MYDTLIIGSGPAGMTAALYAARSNLRVGIIEQGAPGGQMNNTSD
                     IENYPGYDHISGPELSLKMYEPLEKFKVENIYGIVQRVEDCGDYKRVYTEDTHYDTKT
                     VIVATGAKHRLLGVAGEEEYTSRGVSYCAVCDGAFFRNQELLVVGGGDSAVEEAIYLT
                     QFAKKVTIVHRRDQLRAQKILQERAFANEKLDFIWDSVVKEIQGNDIKVSNVVIENVK
                     TGQVTSHDFGGVFIYVGLIPVTQMVSELGITNQEGWIVTDDQMKTSIPGIFAVGDVRQ
                     KQLRQITTAVGDGAIAGQGVYHYIESLSS"
     gene            complement(36429..36656)
                     /locus_tag="TV188_000426"
     CDS             complement(36429..36656)
                     /locus_tag="TV188_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEL1533815.1"
                     /translation="MLVEIFRFYLEGLLLAAITMVMLCLLWILWRAVTKKDKTILQRQ
                     AFLYEMIMVAILTIPILSFAFMSILVVLKAK"
     gene            complement(36766..37509)
                     /locus_tag="TV188_000427"
     CDS             complement(36766..37509)
                     /locus_tag="TV188_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1533816.1"
                     /translation="MIKVTHLTKSFSGQKILDDLTVTIEKGQVIALVGASGAGKSTFL
                     RSMNYLEQPDTGSITIDDFAVDFEHITKEDILTLRRKLAMVFQQFNLFERRTALDNVK
                     EGLKIVKKLSDQEATDIARAELAKVGLSDRENHYPRHLSGGQKQRVAIARALAMKPDV
                     LLLDEPTSALDPELVGEVERSIIDAAKAGQTMILVSHDMAFVYQVADRVLFLDKGKIL
                     EEGAPEQIFRHPKEARTKEFFANYAKTYI"
     gene            complement(37509..38312)
                     /locus_tag="TV188_000428"
     CDS             complement(37509..38312)
                     /locus_tag="TV188_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1533817.1"
                     /translation="MTSTFLTSGWAWYDKLISLIPEGKLFSWHAVFDAIPDIIRRLPI
                     TLGLTIAGAALGLFLALVFAIVKINRVRILYPIQAVFVSFLRGTPILVQLMLSYYGIP
                     LFLKFLNQRYGFDWNINAIPASIFAITAFAFNEAAYTSETIRAAIQSVHTGEIEAAKS
                     LGMTSAQVYRRVIIPNAAVVATPTLINGLIGLTKGTSLAFNAGIVEMFAQAQILGGAD
                     YRYFERYISVALVYWGISILIEQAGRLIEYNMAIKAPIPTNNSKIGELR"
     gene            complement(38689..39516)
                     /locus_tag="TV188_000429"
     CDS             complement(38689..39516)
                     /locus_tag="TV188_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1533818.1"
                     /translation="MTKQLQRALFFLLASLGLLAVVTSHEVTARQKEVIRVATDAATK
                     PFTYRKKHSVTGYDIEVLKRVFKGSKKYRLSIEVVPFPSILAGIDAGRYQIGANNFGY
                     SKERAEKYLFSSPISASHYALATKGKQQYKSLADLSGKKTQGIAGSNYMLILEKWNQS
                     HPDQKPIHLTYASESTPFTQRLQLLENGQLDFLFYDAISLTTVAEEQGFDVHVTKLKE
                     QADTAKDGLEYYVFANDQKGKALQSFVNKRLAKLKKSGQLRKLSQAFLGGDFISKVN"
     gene            40024..40479
                     /locus_tag="TV188_000430"
     CDS             40024..40479
                     /locus_tag="TV188_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533819.1"
                     /translation="MKKAIVSVTLLTVAVLSLSTRFIYSTDYSDLNHKEMARLIQSRK
                     QPVIKYHDNVTINKMITYLAQAKREGILTETFLMNYIFAGEGEYLTKNSRIIADPDGG
                     YWSILEGYEGDGGVKTGIDGVSELNIFSPESTSIGELQEAVLAWYEANK"
     gene            complement(41120..42463)
                     /locus_tag="TV188_000431"
     CDS             complement(41120..42463)
                     /locus_tag="TV188_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1533820.1"
                     /translation="MSFHDYHFKHYIQEALDELGFVEPTEVQQRLIPIVSTGRDLVGE
                     SKTGSGKTHTFLLPIFEKLKEEKEEVQAVITAPSRELATQIFEASRQIAKHSKQEIRI
                     ANYVGGTDKQRQLDKLKLSQPQLVIGTPGRIYDLVKSGDLAIHKASTFVVDEADMTMD
                     MGFLSTVDKIASALPKTIQILVFSATIPQKLQPFLRKYLTNPVIEQIKTETVIADTID
                     NWLLSTKGRDKNEQILATLKAIQPYLAMLFVNTKERADDLHAFLAANGMKAAKLHGGI
                     PPRERKRIMNQVKNLAFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITFYQPSDDSDIKELEKLGITFIPKVLKNGEFQDTYDRDRRQNREKAYQK
                     LDTEMIGLVKKKKKKIKPGYKKKIQWAVDEKRRKQRRAEKRAKGRAERQSRKQSF"
     gene            complement(42546..43553)
                     /locus_tag="TV188_000432"
     CDS             complement(42546..43553)
                     /locus_tag="TV188_000432"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEL1533821.1"
                     /translation="MFLTILAGLIAFAVTALAMPHFIRLYQLKKIGGQQMHEDVKQHL
                     AKAGTPTMGGTVFLLVATSLSFVFALVYFRDGQSLGLISGILLIVLIYGIIGFLDDFL
                     KIFKQVNEGLTAKQKFTFQIVGGLVFYVIHVMPSGIDAINVFGYHWHLGFLYLCFVLF
                     WVVGFSNAVNLTDGIDGLASVSVVISLLAYGVIAYAQGQFDVLLLIGIMVGALLAFFL
                     FNHKPAKIFMGDVGSLALGAMLAAISIALRQEWTLLVIGIVYVLETSSVMLQVTYFKY
                     TKKKYGEGRRIFRMTPFHHHLELGGLSGKAAKWSEWKVDAFLWALGLVASLIVLAILY
                     L"
     gene            complement(43555..45810)
                     /locus_tag="TV188_000433"
     CDS             complement(43555..45810)
                     /locus_tag="TV188_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1533822.1"
                     /translation="MTKWQRYFLDYVVRDRKTPVQNRLRVGQNMMLLTIFIFFIFMIN
                     FMIIIGTDQKFGVKLSDGAKKVYQETVSVQAKRGTIYDRNGTAIAVDSTTYSIYAILD
                     KSFVSATGEKLFVQPSQYDKVAQILKEQLGMEEKDVIKQLKQKGLFQVSFGPSGSGIS
                     YSTMTTIQKAMEAAKIKGIAFSASPSRMYPNGTFASELIGLASLEENKEDGTKSLVGK
                     MGMEAAFDSILSGEDGIITYQKDRNGNTLLGTGKTVKKPVDGKDVYTTLSEPIQTFLE
                     TQMDVFQSKAQGELASATLVNAKTGEILATTQRPTYNADTLEGLNSKSYSWQNILHQG
                     QFEPGSTMKVMTLAAAIDEKVFNPDETFSNANGLTIADATIQDWAINEGISTGQYMTY
                     AQGFSFSSNVGMTKLEQKMGNDKWMNYLTKFRFGFRTRFGLENEDPGIFPSDNIVTQA
                     MSAFGQGISVTQIQMLRAFTAISNDGVMLEPQFVSRIYDPNTDTYRVSDKEIVGKPVS
                     QKAASETRKYMINVGTDPQFGTLHLKSSGPVVKVGQLPVAVKSGTAQIATKDGTGYLD
                     GGLTNYIYSVVAMVPADEPDFLMYVTLKHPEHWAMVFWQDIINPVLEEAYLMKDTLDK
                     PVAVDTSHEATYQLPDIVGQDTGKSADELRRNLVHPIVLGNGSKIKKVSKKAGTNLAA
                     NQQLLILSNHFDEMPDMYGWTKANVATFAKWTGIDIKYKGSSSGRVVKQSVDVGKALK
                     KVKKITITLGD"
     gene            complement(45814..46137)
                     /gene="ftsL"
                     /locus_tag="TV188_000434"
     CDS             complement(45814..46137)
                     /gene="ftsL"
                     /locus_tag="TV188_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEL1533823.1"
                     /translation="MVNEKRTQAVSKALQKRIRTFSRVEKAFYATLILTAVTMAVSII
                     YLQSRKLQLQQHITQLNRQISDKRTELNNAKQEVNELSRRDRIVDIAGKAGLSNRNDN
                     IKKVE"
     gene            complement(46141..47091)
                     /gene="rsmH"
                     /locus_tag="TV188_000435"
     CDS             complement(46141..47091)
                     /gene="rsmH"
                     /locus_tag="TV188_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEL1533824.1"
                     /translation="MTNEFHHVTVLLHEAVDMLDIKPDGIYVDATLGGSGHSAYLLSL
                     LGDKGHLYCFDQDQKAIDHAQEQLKPYIDKGQVTFIKDNFRHLKARLLEHGVTEIDGI
                     LYDLGVSSPQLDERERGFSYKQDAPLDMRMDSQAALTAYEVVNTYDFNDLVRIFFKYG
                     EDKFSKQIARKIEQARAIKPISTTTELAALIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADASIQRAIELLALDGRISVITFHSLEDRLTKHLFKEASTADAPKGLPFIPD
                     ELKPKLELVSRKPILPSQKELMANNRAHSAKLRVARKVRK"
     gene            complement(47194..47610)
                     /locus_tag="TV188_000436"
     CDS             complement(47194..47610)
                     /locus_tag="TV188_000436"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533825.1"
                     /translation="MTRDLKKQETIRDLKTLAFKLESVIEALKELKRWGFFDLFDNGI
                     LTSWVKRQKISAINESLGDVRNLVCRYQKELKVSELRLPSSLSHTRQDKIFDIWLDNS
                     VTDFRVLKETKQVLESAELLYEAVQQALSHLDVKDS"
     gene            complement(47630..48877)
                     /locus_tag="TV188_000437"
     CDS             complement(47630..48877)
                     /locus_tag="TV188_000437"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEL1533826.1"
                     /translation="MTIEQLGQRAKAASRALVSLTTKDKNQFLAFLAEELVAQTDMIL
                     TENAKDLAKAAEHGISEILCDRLRLTADRIHAMAQGVRQVADLADPIGEVIKGYTNLD
                     GLKITQKRVPLGVIAMIFESRPNVSVDAFSLAFKTNNAIILRGGKDALYSNMALVRLI
                     RNALEASAITPDAVLLVEDTSHAVAEELMQATDYIDVLIPRGGARLIQTVKEKAKVPV
                     IETGVGNVHIYVDEAADLEMAVKVVINAKTQRPSVCNAAESLIIHEKVGATFIPMLEA
                     AISKVQQVEWRADEQAKALFSKAVLATEEDYAAEFLDYIMSVHLVSSLDEAISWINQY
                     TSHHSEAIITANINAAERFQDLVDSAAVYVNASTRFTDGFVFGLGAEIGISTQKMHAR
                     GPMGLEALTSSKYLINGNGQIRS"
     gene            complement(48877..49695)
                     /gene="proB"
                     /locus_tag="TV188_000438"
     CDS             complement(48877..49695)
                     /gene="proB"
                     /locus_tag="TV188_000438"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEL1533827.1"
                     /translation="MMKRQFEDVKRIVIKIGTSSLVLANGKINLEKIDHLAFVISSLM
                     NKGKEVILVSSGAMGFGLDLLKMAKRPSQLAKQQAVSSVGQVAMMSLYSQIFAHYQTT
                     VSQILLTRDVVVFPESLANVTNAFESLISLGIVPIVNENDAVSVDEMDHSTKFGDNDR
                     LSAIVARITRADLLIMLSDIDGLFDKNPTIYEDARLRSHVTEITEDIIASAGGAGSRF
                     GTGGMLSKIQSAQMMFEHQGQMILMNGANPRDILRVLEGEKLGTWFKQIERGDA"
     gene            50296..>50719
                     /locus_tag="TV188_000439"
     CDS             50296..>50719
                     /locus_tag="TV188_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533828.1"
                     /translation="MVKLSKRSKIAMSFLIVFCGIFFVAQKRFGSSDQSFTVRPDADF
                     YIVGYHNIEGYQLTNEQPQKISDAKLEVVKGQINQVVKRAELSNRYLVFSEEGPPLGA
                     IGRLIALDFQKGNVTYHPTADYAFTSSGVSPDYYFTSTA"
BASE COUNT        14988 a        11590 c         9689 g        14452 t
ORIGIN      
        1 ctcctttggg agtctttatt ttgcttaatt ctttaagctt gattatatta taattcgaat
       61 taaaacgtat gtcaatagca tttacgaaaa aaatcgtatt tattttaaaa atactattta
      121 caaatacgat ttaaagcgat atcatatgag tataaaaatc gaaaggaaaa taatatggca
      181 agaggaagag gtagattaac acctcaagaa atagaggcgt taggattctt ttcgagcaaa
      241 ttcaatgatc tgctcaacga aacaaataca aagcaagttg aactctcaaa ggctacagga
      301 ataccaccaa gtacgctcac aggttacgta aaagggacat ctttacctat tcccggtaat
      361 gtccaaaaaa tagccgatta ttttgggtta atgaaatcag atatagatcc aagatttgca
      421 cctcgtaaga aaaatcacga acttaagatt cctacttctc cacttgtcaa aaaaataacc
      481 acaactgtcg tggaattaaa tgttcctcgt aagcaaaaag ttttagactt tgcaacagat
      541 caattaaaag aacaaaaaaa taaaatgact tctatggaga aaaaactcta tgagtataaa
      601 gtttacgaga agctttcagc tgggacaggt tatggatatt ttggtgacgg gaactatgat
      661 actgtctttt acgaagaaga attagactac gatttcgctt cttgggtttt cggcgattct
      721 atggagccca cttatttaaa tggtgaagtt gtgcttataa agcaaactgg ctttgattac
      781 gaaggcggtg tctatgctgt tgaatgggac ggacaaacct atattaagaa agtttatagg
      841 gaaaaagatg gattaagatt agtttcttta aataaaaaat acaaggataa gtttgctcct
      901 tttagcgaag atccgcgtat aatcggcaaa atcgtcggca actttatgcc caaagaatat
      961 tgaggtgtgt tatgggattg tttaatttcg gaaaaataaa agatgtggct ctagaaaaga
     1021 aattacaaaa gttacaacaa aaaattgaaa atgaaaaaga aaaattgagg gaaattaaag
     1081 aagaaattgc attagccaat gatacattag accttcaaga atatggtttt tttgaacgcc
     1141 agtataaatt ttcccatagt actaaatata aagatgcttt agatacgtta cgaatgaaac
     1201 aaaaaacact cataaaaaat ggtgaagcta caagcataat ttcccccatg actctagatg
     1261 gtagtgcagc aaaaggtaaa gcaatgcaga accaacttag gaaagctgca atccgcggct
     1321 ttaatggtga agccgatgcc ttactagtta aagtgtctgt cgtaaatgta gataaaaaag
     1381 tgcaaactct tcagaaggct ttcgaacaat taaataaaat gtatgaaagg aacttgatcc
     1441 aacttacctt taaatattta gatttaaaag cacaagaatt gagattagct gctgaatacg
     1501 aattgcaaaa acaagaagaa aaagaaattc taagagaaca gcgtgcaaga gaaagagaag
     1561 ataaaaaact tcaagctgag attactgcta aaagaaaaca acttgaaaaa gacaggaagc
     1621 actttttaca aatggtcaag aacgtcgaag tgatgcttgc taacgcttct ccgaaagaac
     1681 aagagaaatt acaattgcaa ttaattgaat accaaaacaa gctctcagaa cttgataaga
     1741 ttgaagaaga cattgattat agagaaggac atgcaacagc tggatatgtc tatgttattt
     1801 ctaatatagg tgcttttgga gaagatgttt ataaaattgg agtaacaaga cgtttagacc
     1861 caatggatcg tattcgcgaa ttggggagtg catcggtgcc ttttactttt gatgttcatg
     1921 cgcttatctt tagtgaggaa gcttttgctt tagagtctga gttacataat aaatttgaag
     1981 cgtataaagt aaataaaata aacagtcgaa aagagtactt tagagttccg tttgctaaaa
     2041 tcaaagaagt tctagaaaat cataaagaat tagctattga gattaccgaa gaagctgaag
     2101 cgtttgaata ccgtcaaagt atcttgaaaa atgggggtta aatatgaaat ggttattcct
     2161 aattttattt ataggctgcg gtgctaatgc tgtaaacctt tctaaaaaag ttaattccga
     2221 tgatgaagtt gacgaaaaca acagtcacct tatatcacat tcaaatgaag agattccttg
     2281 gaataaaaaa gaacagcttt attggggcac tgcttccatt gtatttttag tgctttttat
     2341 aatctaaaca caataataaa aagcctcacg ctcaactttg gtcgatgcga gcgtgaggcg
     2401 aacgtgtata gtaaaaacct gctttgcagt aggtctcttt actataccca ttttaacata
     2461 aaaatgaggt gaaaaacaat gattacaaca agaaaagtcg ctatttatgt tagagtcagt
     2521 acaacaaatc aggcagagga gggctattca atacaaggtc agatagacag tttgatcaaa
     2581 tactgcgaag ctatgggttg gattatatat gaggagtaca ctgatgctgg cttttcagga
     2641 ggtaagatag accgtcccgc catgtctaaa ctaattacag acgcaaagca taaacgattt
     2701 gatacaatct tagtttataa gctagacaga ctctcccgaa gtgtcagaga tactctttac
     2761 ttagttaaag atgtttttaa ccaaaacaat atccattttg tcagtctgca agaaaatatt
     2821 gacacttctt cggctatggg taatctattc ctcacattgc tatctgcaat tgccgaattc
     2881 gaacgagaac agataacaga gagaatgaca atgggaaaaa tcggaagagc aaaatccgga
     2941 aaaactatgg cctggactta tacccctttt ggctatgatt acaacaaaga aaaaggcgaa
     3001 ttgattttag atcctgcaaa agcgcctata gttaaaatga tatatacaga ttatctcaaa
     3061 ggtatgtcta ttcaaaaaat agtggataaa cttaataaga tggactacaa cggtaaggat
     3121 tgcacttggt ttccacatgg tgttaagcat ctattagata atcctgtcta ttatggtatg
     3181 acaaggtata ataataaatt attccccgga aatcatcaac caattattac aaaagagcta
     3241 tttgataaaa cccaaagaga aaggcaacgc agaagattag gaatcgaaga aaaccactac
     3301 acaatacctt ttcaggcgaa gtatatgcta agtaaatttt taagatgtcg tcaatgtggc
     3361 tcaagaatgg ggcttgagct tggcagacca agaaaaaaag aaggcaaaag atccaaaaaa
     3421 tactattgcc taaatagtag gccaaaacga acagctagtt gcgacacacc actttacgat
     3481 gcagaaacct tggaggatta tgtgttacac gagatagcca aaatacaaaa agatccgtca
     3541 atagcgagca gacaaaaaca tattgaggat cacgaattaa aatacaagcg tgaaagaatt
     3601 gaagctaata tcaataaaac agtgaatcaa ctctctaagc taaacaatct ttatcttaac
     3661 gatctgataa ctcttgaaga cctcaaaact cagacaaaca ctcttatagc taaaaaaaga
     3721 ttgctagaga acgaactaga taaaacttgt gataacgatg atgaacttga cagacaagaa
     3781 accattgctg actttctcgc cttgcctgat gtatggacca tggactatga gggtcaaaaa
     3841 tatgctgttg agctgcttgt tcaacgtgtt aaagttgata gagataatat agacattcat
     3901 tggacttttt aatgccaaaa attacaaagt tttcaaccct tgatttgaat aagactgctg
     3961 cttgtgtaaa ggcgatgatt ggctaataag acaaagacat ctacggttgg aaaggtcaca
     4021 cctctttcca aaatggttgt tgatataagt atagtgattt gtccttgtct gaattgctca
     4081 atgatagcca ttcgatttga tgactgactg gaagcatgag caatagtttc cttaggaaaa
     4141 tacttgtgga gcagctgaca gcattgctca gccagctcaa taatcggaaa aaagattaaa
     4201 agaggatagc cggttgccct ttgttttttg actagggtga tgaaccttct aggcaatttc
     4261 ccacgattga tagcctctaa aagggagaat aatctttgat actttggaac aactaagggc
     4321 ttgccatgga atcttcttgc caacgtcaat ttgacaagct ctttttgctg accttgcgct
     4381 ctaaatctct tgtagaggtt gctgttaggt atactgtcac tgcatctgct tttgcagcct
     4441 gatgagcagc atggtttaat tgacgattat tgacaaaggg gaaggcatct acttcgtcaa
     4501 taatgagcag atcaaaagca tggtaaaagg tcatcaattg atgtgttgtg gcaacgataa
     4561 tggggcttct atgataaacc tctgactcag catgcataag gcagacttga caggaaaagt
     4621 cccgcgatag tcgtttttca agctctatgc aaacatcaac tcgtggacta gcaatgcaga
     4681 cccagccacc cttattaaca actgctgcaa tagcttcata catcatctct gttttgccag
     4741 caccagtaac cgcatgaact aaggtgtctt gcttgagctt aacatggtta gtaagctgat
     4801 gagagatagc tgcctgatat gtcgtgagct gtccttgcca cctcagataa tgtccctttg
     4861 gaaaagaagc cggtggaaaa tagagcaagg ggcgatcaga ttggtttcga ccaaaaacaa
     4921 gacaggctct acagtagtaa gcaccgctag gcagctgatg agccttctca attaaactgc
     4981 tacagcgttg gcagtataac gttccctttt tagtgatcat gctttgtaag ctgcaagccc
     5041 aggcagaaac agcctttggg cattgccttt cgggtaaaag acgtccatag taattttcga
     5101 tattctccat accttattat ccgaattatt ttgctaaata tcagcatttt ttgtaaaatt
     5161 ttcttatgga agattataaa actattatga ctgatgggct ttttgaggaa agcatcaaaa
     5221 aatctcgctt tatttgccaa atcaaacgcg tctacacaga agaggaggcc agagccttta
     5281 ttgctgacat caaaaaaaag cactataagg ccaatcattc ctgctctgct atgattatcg
     5341 gagacaaagg acaaaccaag cggtcaagcg atgatggtga gccatctggt actgctggta
     5401 ttcccatgct atctgtctta gaaaggcagg aattaaccaa tcttgtagct gttgtgacac
     5461 gctattttgg aggtgttaaa ttaggagctg gagggctcat tcgcgcttac tccggcgtaa
     5521 ctgcggcagc tattcaggcc ttaaaggtcg ttgaggtaaa aaaacaaact ggactagcaa
     5581 tcagcctcac ctaccctcaa taccaaatct atcctaattt tctggagcaa gaagcattga
     5641 ttgaaatgaa taccgaattt tctgatgtcg tcagaacagc tatttacttt gatcctgagc
     5701 gcttggagag tatttctaag gcattgattg agcattatca tggcaaggtt tcctttgaag
     5761 agatcgaatc gcaaaggatt gaggtccctg ttttgcctgc caattagcat gaacagtgat
     5821 agcgtctctt tatcactacg atagtaaatg gctattttac tttgtcgatt attagctata
     5881 tacttttata taagcatgta ttgatacaag gataaaaagg aggacctatg tcaaagctat
     5941 atcacaacat tacagagttg gttgggaaaa cccctattat taaattgaga aacaccagtc
     6001 cagaggaggc tgccgatatt tatgtcaagc tagaagcttt taatccaggc tcttcagtta
     6061 aggatcgcat agcacttgca atgattgaag ctgctgagaa agcaggcatg atcaagccag
     6121 gtgatacaat cgttgagcca accagtggca atacagggat tggcttatcc tgggttgggg
     6181 ctgcaaaagg ctaccgagtg ctcattgtaa tgcctgagac aatgagtatt gaaagacgtc
     6241 aaatcattca agcttacgga gcagagctcg ttttaacccc aggtagtgat gggatgaaag
     6301 gtgcgattgc taaagcagaa gagattgcca gagagaccgg tgcttggatg ccctcgcaat
     6361 ttgacaatcc tgcaaatccc aaggttcatg aagagacaac agggcaagaa attatcgcgg
     6421 tttttggaga aaaaggactt gatgcctttg tttctggtgt gggaactggt ggcactattt
     6481 ctggcgttgc gcatgcctta aaggctgtta atcctgatat ttctatctat gctgtggaag
     6541 cagatgaatc tgccgtctta tctggtgaag agtcttctcc gcacaagatt caagggattt
     6601 cagctggctt tatcccaaat accttagata caaaggccta tgaccacatc attcgagtag
     6661 cgtcagaggc tgcccttgcc actgctcggt caatcggggc taaggagggc tttcttgtag
     6721 gcatttcttc tggagccgct gtttatgctg ctatccaagc tgctaaggag cttggaaaag
     6781 gtaaaaaggt cttagctata ttaccagata atggtgagcg gtacctgtct actgcccttt
     6841 atcagtttga ttagaataat catataagca ccagccctag cagctagaat aagctttcaa
     6901 gcataaatca tcgctcttac ttagtcacca ttaaaggcca gtcagctagc atatggaaaa
     6961 atgcttactt tgattccttt ttaacaataa acatagcata ccacgcctaa gcgccccaga
     7021 gcttctagct tcttggaaat aggctttcct agccgctttc accacagtaa aaaagactca
     7081 agctagtagg ctaagatgtt caaagaggac tagcaatcac aattggcttt ttttgaagat
     7141 agctttgaga taagtaaggt gactggtcca gagctgatag caaaaaaccg aggaacagtt
     7201 catatagctg tttctcggtt ttttatgttt ccaagtctgt ttacgatttt tcctgcttaa
     7261 agtggtctaa gccttcctca atccaattgg gtaagctggc ttcaagaggc ttaaagccaa
     7321 tcttataacg gctgtttgaa aagcgatgat gacttgacac atgatgcttt tcctcctcca
     7381 aagttctcaa ggacaggctg accttatgac tgtattcgtc atagtcaatg acctgaacta
     7441 aaaccgcctc accaagtctt aggatctgat gaatattatc aataaatccc gtcttaattt
     7501 ctgaaatatg aatgagacct gttgtcccat tttcaagggc aacaaaggct ccatagggtt
     7561 tgattcctgt aatggtccca tgcagcttat cgccaatttt catcaatcaa atacctcgat
     7621 ggcctcaatg acaacgtcct cttttggctt gtcttgtgcc cctgtttcga cagcagcaat
     7681 gttatccaag acctgataag aggcttcatc agccaactga ccaaatactg tatggcgacg
     7741 atccaggtaa ggagtccccc catgttcagc gtaggctgct gcaatgtcct ttggccagcc
     7801 accacgctct aattcctttt gagaataagg aaggcttgta ttttggacga taaagaattg
     7861 gctgccgttt gtatttggtc ctgcattagc catcgaaagg gctccgcgaa ggttgtacaa
     7921 ttcctctgaa aactcatcct caaagctttg accatagatg gattgcccac ccattccagt
     7981 gccagtcgga tctccacctt gaatcataaa atctgcaata atacgatgga aaataacacc
     8041 attatagtag ccttccttag ctagacctaa gaagttagca actgtttttg gagcatgctc
     8101 tggaaataaa gccaatgtca gctcaccatg atttgttttc atcaccactc ttggtccttc
     8161 atggccagcc aaatctagct gcggaaaatg taattctttg tcaatcaaac ctaattcctc
     8221 caaggcatat aaaatgccgt tttcttcaac tgttttagta ataaaatctg ctttttcttg
     8281 taattgtggg tgagaaaccc ccatagcaat gctgatgcca gcataatcaa atagctctaa
     8341 atcattgagc tcatcaccaa agaccaggat attttcaggc cttaagccca aatgctcaac
     8401 aacctttgat acacctagag ccttagaggt gccctttagg accacatcag aggagtgatc
     8461 atgccacctt actaggcgaa gctgctcagc caattcaaca ggtaattgca ggtcatctcc
     8521 cttgtcctca aaggtccaca tttggtagac atcatggtgc tcattgtaat ccgggcatac
     8581 ctctagtgtg gagtaaacct tatcaatagc atcactaatc atctcgttac gagctgataa
     8641 gacagcctcg tgacgtcctg ccatgccata atcaatgccg actgcattgg cccatttttt
     8701 ataggctaca acagtgtctg ctgggatagg tgcctgaaag ataatgtttt tttgattgtc
     8761 cttcacataa gcaccattta gcttaacaca ataatctgcc tgtaaatcct gaacctcctt
     8821 gggcacacca tatctggcgc gacccgaagc aattcctgtt aggatccctt ttttcttgag
     8881 ctctttgaaa accctctgga tagactctgg catatagcct gtgttcttta cgcgcagggt
     8941 atcatctatg tcaaagaaaa ccatcttgat tttcttggcc ttatacttta gttttgcgtc
     9001 catactttcc tccatgcaat agtactatta tagcattaat gatcatcttg aggcactaaa
     9061 tgatgtcgga aagcgtatac aacagcctga gtacgatcat caacctgcaa tttggctaaa
     9121 atatttgaca cgtgagtctt aactgtcttc aaggaaataa aaagctcatc agcaatggtc
     9181 tggttatcat agcccttggc caataaatgc aaaatatcgt attcacgcgc tgtaagctct
     9241 tcatgtaaat taggctgctg atcatgtgcc ttaatcttct tgtcaacctc cgtttcaatg
     9301 gcaagctcgc ccttagcaac ctttctaatg gcatttaaga tttcagctgc acttgatgtt
     9361 tttaacatat agcccttagc tcctgcatca atgacagggt aaattttttc attatcaaga
     9421 taggaggtta acaccaacac ccttgcttcc ttccatttgg agagtatttc tagggtcgcc
     9481 tctacacctc ctaattcagg cattaccaaa tccataacca cgacatctgg tctcaattca
     9541 agggcaagct caactccctc acgaccatta gaagcctcac ctatgacatc aacatcttgc
     9601 tgcaaattta agaagctttt taagcccatt cggaccattt catggtcatc aactaatatt
     9661 acggttatat tactcatctt catctcccat cacaagtggc agtctaatgt ccatcgaaac
     9721 gccctttcct ttttgactaa tcaaacgaag cgttccagcc aggtcattca cacgatcttc
     9781 aatattttta aggccatagc ttaattccct aacctgaccc atgtcaaaac caaccccatt
     9841 atcaaccatt tttagctgta gttctgttgg tgtttggttc aagtacacct caaggcggct
     9901 cgccttagca tgcttgaggg tattgctgat aaattcctga gcgatcctaa agagattatc
     9961 ctctatggcc tttggcagag tgccaatatt ttctttatag acaacctcaa tgccgctttt
    10021 atcagttagt tccttgagaa tcatcgtaaa gccctctgac aggctacgat ttgccaattc
    10081 tgtcgggcgc aggtgcaata ataaaatgcg taaatcattt tgagcatttt gcagcatggc
    10141 ttcaacagta actaattgtt gctgtagctg ctccttatcc atctgatcta ggctcataga
    10201 aacccctgac aaaatcatcg acgaagcaaa caattcttga ctaacagtgt cgtgcaggtc
    10261 tctagcgatt cgtttacgct cctgttgaac aattttttga ctatctaaaa tataagcatt
    10321 ctcttttttc tggatattgg ttgttatatg agacattttc gcagaaagtc tggtcaaatt
    10381 cgtgttgatt tcagaggtct cctccaaatg aattctttga ttgttgagaa tcctgcgtaa
    10441 atttttattg atgctccgct tgctattatc atctaaaata atccacaaca aaagcaacag
    10501 caaggttaca gagatgataa gcagcacaac tgaaaacacc aagcgctcta gctgccataa
    10561 atggctccgc aagtagtcaa aggtgatccc cagattatcc atcacaacaa aaacaattga
    10621 taaaatggtt atagtcgaat aaagccagac caaagcataa tacctttttt tcatcgtcta
    10681 gccacctcga catttcctgc tatagtggat acgataatct taaccttctt taaactgctg
    10741 tcctcggcct ctcctagggt gatggattca tttcgtaaat cgtactcttg aagctcaaaa
    10801 aaatcaacac tagcatagat agagctgacc tctaaggtaa cagccacatc aataggcact
    10861 aggatctttg tgttgccaaa gatctttctg ataatgatga cattgtccat tccagtcaca
    10921 atcacatttg tcagatcaat cgtatcattg ccagaggcac gaataatatt gatatcctca
    10981 aaggaataat aatcactttc atagttagct gcgccaagcc attgattttt gacctgtcgc
    11041 acagtcattt tttcttctgc aaaccgaatg agggcaaatc gattcttctt ttttacctgt
    11101 gaaaaatgat tgataatcac atacacaatc cccaacagaa ccgccataat aatataaggg
    11161 ttcagcataa aaattaagaa taaaagcaat aagctaactg ttagcaaaaa gctattgcgg
    11221 gtatcttgat tataaaaacg cagagccaat aaaatcaaga ccaaaattaa aataaagctt
    11281 gataagtcgt tggccaaaat ggtcataatc cccatagcca gcagcatgca ttcaacaagc
    11341 agaaagaatt gaaatttttt cattagactc cttccattac cctgacattt tatcaaaaat
    11401 taagcaaaaa ttcacccttg agtggcattc tagtaaaaaa gaatacctag cttagcaact
    11461 atgggcaagc cagatattct atatcctatt tacgtttacg gtgttgtaac agcgtcattt
    11521 tgacctaatt cggtatgact gcttgagtct gttgtatctc cagctgatgg attaggagcc
    11581 gaggtatcag agctcgatga gctgcttgat gcacgtgtct cctcagggta gaggtagagg
    11641 ctaatatcac ccttttcaga aaggctaatc tgggtaccat aatacggtgt ttgcccactg
    11701 acaaccgcct ttgagcttgg ggagctcacc tgcacaaagc ctgtcggaga gctggagctt
    11761 ggtacatagg ccttgattct tgcggcatca attcctaaag ctgttagtgt attgactgca
    11821 tctgcatagc tgtactcagt taccattggc atgatgactg tatcacccac tgctacactg
    11881 agggtaatct tggatttacc agctgggtta aatttttctc ctgcgcttgg agactggcta
    11941 ataacggtgt tttcagggta ttcatttgtc acgatacgct caatcttgat ttttgacttt
    12001 ggtacgccat aggtctcagt cagactggtc atcacatctt gataatcctg tcccttataa
    12061 ttttccatct caaagccttt atttccgatc gaaaggtaaa ggtcaacgct ggagcctttt
    12121 cgcttagctg agccagcttg aggatttgtc ttaaccacct gatcctcact aactgtgtca
    12181 ctttcaatct gatggacctt accgaccttt agtcccgcct cctccaagac ctgcttggca
    12241 gcattgagac tagagcctgt cacatcagga accttaaccg tagttggctt ggtcaagacc
    12301 aaataagcaa aaagagccac accaacaaca aaaaaggaaa acaagatttt taagagtgtt
    12361 cctagaaaac gcccattttt tttctttttt tgaggctttt gcagagtatc catctggcta
    12421 gtctgctcaa gtctagcatc aactgccgca gatgcctgac tagcatttga taccttaggt
    12481 gctgttacag gagtcggtgt tacctttggc aagggctttg tgctttcgac atcatcaaag
    12541 acaaccttac gctcacgact gcggttatag ctaagggctg tcatcaaatc cctgctcatc
    12601 tcaaaggtcg agcgataacg gtcacttagc tttttggcag tagcccgaat aacgacgttt
    12661 tccaaggctt gaggcacatt aggattttca tcaatgatag agggcagcgg cttttgaaaa
    12721 tgctgcaaag caatcgtcac agcgctatcg ccatcataag gaatatgccc tgttagcatt
    12781 tcaaagagca taattcccat cgcgtaaata tcactttgaa tcgtcgcttt agaaccacgc
    12841 gcttgctcag gtgagaggta atgcacactt cctagcatag aatttgtctg ggttagactg
    12901 gtctctgcaa aggcaacggc aatcccaaaa tctgtaacct taacaacact tgatttggtc
    12961 aaaagaatgt tttgaggctt taaatccctg tgaacaattc ctttttggtg ggccagagtc
    13021 atggcagaaa gaacctcttc catgattctc accacctcat tgttagataa tggcgcatga
    13081 tcctgaatgt attttttcaa gtcagagcca tcaacatatt ccattactaa aaattgctgt
    13141 ccgtcttcct cgcctatatc ccgaatggca acaatattgg ggtgatttaa ttcagccatg
    13201 gctcgcgctt ctctttgaaa acgcgcaaca gcaacctgat ctgtttgata attggtccgc
    13261 aagaccttaa tggcaacgtc ctcattatcc agaatcaaat cgtttgctaa ataaacatcc
    13321 gccataccac cgcggcctat agattttaga atgcgataac gaccagcaaa tagcttgcca
    13381 atctgaatca ttctgcttcc ccgctttcct tatgcaccaa agcaacggtg atgttgtcta
    13441 ggcctcctct ttggtttgcc aggtcaatca aggcttgatt tttctcatca aggctgatgt
    13501 cttgacataa tatgtcaaca atctcctcat tagcaatcat attggttaag ccatcactat
    13561 taatcactag gtaatcgccc ttttctaaaa ccttgacacc taagtctggc tctaccggtg
    13621 aagcttgacc tatagattgt gtgatgatat ttttttgtgg gtggctagca gcctcctctt
    13681 cggtaatctg accagccttc actagggcat taaccaagga atgatcactg gttaaaagac
    13741 tataatttcc ctcatgaacc aagccgatac gagaatcgcc aatatgggca taaatcgcat
    13801 tagaatctac tagagcaact gcctcaacgg ttgttcccat tcccttatag tcttcagatt
    13861 gtcccaagtc gtagatacgt tggttctctg cttcgatggt tgttaacaac caatccttga
    13921 tctgactaag ctcagtaaaa tctgtcttaa cccactctct acctaggtct gtaacggtca
    13981 tctcactggc aatatttcct gccctatgac ctcccatacc atctgctagg ataacaaggg
    14041 taatgccttt tttattatca aatttgttga taaaatcttg attgtttgag cgcttttgcc
    14101 caatatcggt ttttaatgaa atcttcatat aatcttttct gactaggtca gtctcctcct
    14161 aaatactaca agactcgtct gacttgccca ataaagaagc catcagtctg gtattgctct
    14221 ggtgtaatca taagacaacc gtccttgaca atatctgctt gtgcatgctt gagtgttact
    14281 tgttcaaaat taggatgacg ttgtaaaaat ttgtcaataa cttggaaatt ctcttcatca
    14341 aaaatcgtac aagtgctata ggttattata ccaccttttc gcagcgtttg acaaacgcta
    14401 gacaatatct ccagctgaat ttcctgcaat tgctggaagt cctgcccttc cttgttgtat
    14461 ttaatatctg gcttacgcct gatgaggcct ataccagagc agggagcatc aactaaaatc
    14521 ttatcaaagc tgttcttcgc aaaatgctta tgaacctctc tagcatcaag caccttagtt
    14581 tcaatccgat ctgctacccc tagacgctta gcattttcat tcactaaggc cagcttgtgc
    14641 tcatacaaat caagggccac tactttgccg ctcgtcaaat aagaggcaat gtgagctgtt
    14701 ttccctccgg gtgcactaca agcatctaaa atcatttcct gcccttgaat atccagcgtc
    14761 ggggcaacta gctgactggt ctcatcttgg atcgtaatgt ccccattgat gaaataactg
    14821 ctggcagcaa aattgccagc tctcttggtc agaccagtcc tagcaagtaa tgattgctct
    14881 gatcctgttg cctgcttgat ctcatcaagc tttgtcagat ctgtgacacg tatgctggct
    14941 ctgcttctca caaaaagact ttccatgatt gctacagctc gctcctcgcc aaattggtcg
    15001 atcaattttt tgactagcca gaccggtact gagtaagcaa cagcatagta tttgtttttt
    15061 cgcttgatgc tcttgatatc tggtaagggc ttattggtca gctggcgcaa aacggcattg
    15121 accagcttat ctgctcctct gccatgagct ctcgccttgg caagattaac agcgtcatta
    15181 acaatagcat gagcaggcac cttgtctagg taagccagct ggtaaaggct aagcatcaag
    15241 agataataaa cccatttatc cagcctgtct cggtcctcaa tatagtgagc cagataccat
    15301 tctagggtta tcttcctaga gatagtcccg taaacaatct ctgtgactag agccttgtcc
    15361 ttatcactta aaaactgatt cgccagctgg tgcttcaagg caaggttaga ataggctcca
    15421 tgatcaaaaa tatcctcaac gataagcagc gcctgtcctc tagctgattt tttccaatca
    15481 ttcgccaagg acatcaccca cctctaggct tctgccaata ccatttaaaa agtcaacaat
    15541 aggcatcttt ggcttgcctg ctggttgaac gagcgtcaag gatagagccc cctcacctgc
    15601 tgctacgacc aatgcttttt tagttttagc gatgatttgc ccagcagatc cagagccttc
    15661 agccaattca gcctcataaa ttttgaagcg ctgcccatct aataaggtat gagccaccgg
    15721 ccaagggttc attcctctga tatgattaaa cacctctctt gctggctttg accagtccag
    15781 tctttcttct tctgctgaaa gattgggaga aaaggtggct tggctatggt cttgaggaac
    15841 tggctttagg tcaccagaca agtaatcagg caaggttttc aataataaat ctcgtcctag
    15901 aatggccagc ttatcaaaca tggtaccaac attatcagta tctaaaattg gaaggcttgc
    15961 gcttgatatc atatccccag cgtccatctc cttaaccatc tccataatgg taactccagc
    16021 ttccttgtca ccattgataa tagcataatg gatcggagcg ccaccacgat atttaggaag
    16081 taaggacgcg tgcacattaa cagcaaatgt caccgaatcc aataagactg ttggtaaaaa
    16141 ttgcccaaag gctgccgtta caatcccgtc tgctcctaat gccatgatat ctgctagctc
    16201 ctgtgaacca gatagcttct caggctgaaa aacaggcagc tgatgtgcaa gcgccagctt
    16261 tttaacaggc gtcattgtga tgtctttttt gcgaccaacc gcacgatcag gctgggtcac
    16321 gaccgctaaa atgtcatagg ctggtttttc tagtaagccc tgcaaaacag ttgctgaaaa
    16381 ttggggagtg cccataaaaa ttaatcttgt catctatgtc ctctattttc tttctttttc
    16441 attatagcat agcttggcgc aaagtccggt aaagaacact tacataaagc tctgtggctc
    16501 ctgatcaatg ataaccttta gctcgcgatt atcctgctct tggctccaat caagaatttg
    16561 attcagggta gcttcaagct gatcctcaaa gcgatacttc aaaataatct gataatggta
    16621 aagattgtgc gttcttgcaa ttggctttgg cgttggccct aatattctga tctgatcaga
    16681 caagccctgc ttcaatatgg tcagcagttg ataggccttt ttgaccacct cttgctcact
    16741 cttatgcgat agggtcagac ctactgtgaa ataataggga ggatagccta gctttcgtcg
    16801 aatccccatt tcataagcgt aaaaggcttc aaaatcctgc tttttggcca gttgaatcgc
    16861 gtaatgctca ggattgtagg tctgaatcag gacttcacct ggcttgtctg cacgtcctgc
    16921 acgtcctgca acctgagtca gcaattgaaa ggttcgctcc gatgccctaa aatcaggtaa
    16981 atgcaaggaa gtatctgcat ttaaaacacc tactagggtg acgttgggaa aatccaaccc
    17041 ctttgcaatc atttgtgtcc caagcagcac atcagcatca ccatttccaa actggcttaa
    17101 aatagcctca tggcttcctt ttttacgtgt cgtgtctacg tccattcgta atattctagc
    17161 ttccggcaac acttgcttga gctcatcata ggctttttgc gtccctgttc cataatagcg
    17221 tatgcttttg ccttgacagc tagggcatag cttcggaata gccctttgaa agccgcaata
    17281 gtgacaattc atggttttcg tatccatgtg gagggttaag gaaatatcac aatttggaca
    17341 ttgatcaaca tagccacaat ctcgacacat gataaagcta gagtagccac gcctgttgag
    17401 catcaaaaca gcctgctctt ttctagcaag acgctctttg agtttatcaa tcaaataagg
    17461 ggtgaagctg ctaacctcct gctgaccaat ataatctcga aaatcaacaa tctcaacctg
    17521 aggcatactg gcaagaggat tggctctctc agtcagctgg ataaactgat acagtccctt
    17581 gctggctcta gcgcgactat caatactagg ggtcgctgag cccatcacta aggcagcctt
    17641 atggtgcctt gcacgaatga gagctacatc tctggcatgg tatctgggat tagattcctg
    17701 cttgtaggtg gcctcatgct cctcatcaat aataatggct ccaatatttt ctaaaggtga
    17761 aaaaatagca gagcgagcac cgaccaccac tctagcctgc cctgtcttaa ttttctgcca
    17821 ttcgtcaaat ttttctccat ctgacaaacc tgaatgcata atagcgacct gtcttccaaa
    17881 gcgggaaata aatcgagagg tcatttgagg cgtgagggag atttctggca ctaagacaat
    17941 agctgtcttt ccttgctcaa gcacatgcgc aatcacatga agatagacct ctgtcttgcc
    18001 agagcctgta ataccttcca gtaaaaaggg cttagcctct ctgccaacag ccttcgtaat
    18061 ctggtcaaca gcttgctgct gctgctgatt aagctttaag agtggggctg ccttgatgtg
    18121 attgaaataa tcctcactgc gattgacacg tcgctcctca agctcgatca gctggttggt
    18181 cacaaaatag ctaacaacct ctctagaata atcctgataa agcttggcta gcttatcttt
    18241 ttgtggattg gctaacaaat aagcctttaa ggcttggcgc tttttagccc gatttgaaat
    18301 cttatgctcc tgtaaggcta atctattgac ctgatagtaa gtctcggttt tgattgtctt
    18361 tttgtccttg gctagataag ttgccctaat cttaccagac tgtatcagcc taaggacacg
    18421 tccctcctgc tctggactta gcttagaata aagcaaggaa tccccattag agaaaacatc
    18481 agcaaggtca gccgcagcta agtcagctgt cggggtgagc agccgatcgt aatgagaatt
    18541 aagtaggcta ggaagcattg cctttaagag ggtgattttg taggaaaaga ctgtttgtcg
    18601 taattgctct gctaatgcca cctgctcctg atttaaaaca ggctcagcat ctaaaactga
    18661 ccaaatagcc ttcaattgct gcgttgattg actagaaaag ccaataacaa agccctgtag
    18721 caacctattg ccattaccaa aaggcacatg aacgcgagaa ccaatcttaa ccagagataa
    18781 tagctcatct ggaataagat aagaaaaggg cttatcggtt tgcatcaagg gaatatcaac
    18841 aatgacctgt gctatgtgtt gcattttgac ttcctttcta tcaagaaatg gacctgcaat
    18901 atgaaaaaaa ctaagattga ctcaacctta gattttttct ccctcttctt ctttttcttt
    18961 tgcaatctgc tcttttattt tacgctcttc ttcttctctt gctaaacgct ctgcctcaat
    19021 ccttgcacga acagccgcac gcttagcagc aggatccggg tgaatcacaa cattgcctga
    19081 ctcaatctcc tctagtgcct gaagtgttga tttgacagac ttaaaggact gtgtcggtgc
    19141 agcacctgct tctaattcat gagcacgctt ggcctgtaaa ataacaagtg aatattttga
    19201 tgggacttta tctaataaag tatcaattga aggttttaac atcatgggct ttactctttt
    19261 ctatttctat catctgagag attttgttgt tttaatcatt tgatcatagc gaccaatcac
    19321 acgctcaacg cgaaaatgct cggtctcaat aatacgcttg acacgctctg cagctaaagg
    19381 aacctcgtcg ttgaccacag cataatcata ctctcgcatg agcgcaatct cttccttagc
    19441 tctttcgata cgcttggcaa tcacctcttg gctgtctgtt ccacgaccaa ccaaacggtc
    19501 ctgcaattca tctaagtctg gcggcgttag aaaaatgaag acaccatcag gcaccttagc
    19561 cttgacctgc aaagcaccct gtacctcaat ttccaaaaag acatcaatgc ccttatcaag
    19621 ggtttcgtta acataggtta agggagtgcc atagtaattg ccgacatact ctgcatattc
    19681 tagcatttga ccatttttta ttagctcttc aaattcttct cgtgtgcgga agaaataatc
    19741 aaccccatca acttcacctg gtctctgtgg acgtgtcgtc atcgaaacag aatattcaaa
    19801 tttatgatct ggcgttgaaa aaatctcttg tctcaccgtt ccctttccga cacctgaggg
    19861 gccagagaaa acgattaaca aaccgcgttc agacattgtg ttctccttat tgattgcttt
    19921 ctaatagttt atcaaaaagg ctatcgtttt tcaagacaat tatcagccca atcctaagaa
    19981 agaaaaggaa gagatagacg ccttctcaaa gctagaggct aaactctggc ttttgaaaag
    20041 catacactct ttccttttta tttcgcataa tctattgctc gcaactcacg aataacagtt
    20101 accttgatat ttcctgggta atccaagtta ttttcaatct tttctcttac cttgtgtgag
    20161 agaaccacaa tctcgtcatc agaaatcttt tctggctgaa ccatgatgcg aatctcacga
    20221 ccggcttgga gggcaaagct actttgaaca ccatcaaagc ttgttgcgat ttcttcaagg
    20281 tcacgaagac gcttgatata gttttccaca gattcattgc gggcacctgg acgagcagag
    20341 ctaagggcat cagcagcagc taccagaact gcaataaccg aatccggctc gacatcgcca
    20401 tgatggctgg ctatggtgtt cacaacaaca gggtgctcct tgtacttgcg agcaaactcc
    20461 ataccaatct caacgtggct tccttcaacc tcacgatcaa tagccttgcc catatcatgc
    20521 aagaaacctg cgcgacgtgc aagtgccaca ttttcaccaa gctcgccagc taaaatacca
    20581 gctagcttac caacctcgac tgagtggcgt aaaacatttt gaccaaatga ggtacgaaac
    20641 tgtaagcgcc ccatgatctt aatcaaatcc gggtggaggt taggtgcacc gatctcatag
    20701 gcagcagcct caccatactc acgaatccta ttgtccatct caagacgatt tttctcaacc
    20761 aattcctcga tacgcgccgg gtgaatacga ccatcagcaa tcaaggactc tagggtcata
    20821 cgagcaatct ctcgacgaat agggtcaaag cctgataaaa caaccacttc cggggtatcg
    20881 tcaatgatca catcaatccc tgtcagactc tctagagtac ggatattgcg accctctcga
    20941 ccgataatac gccctttcat gttatcatca ggcaagtgca cacttgtaat cgtctgctca
    21001 gtcacatact caccagccat acgttgcatg gcctgtgcta acaggtcctt agcagtcttg
    21061 tctgtcctgt ccttgatgtc acgctctgca tcacgaatgc gtgttgcgat ctcatgcgtc
    21121 agcttgtttt cagtttccat caggataacc tcacgcgctt ctgcaatggt catagcagca
    21181 actcgttgga gctctgctct tttgtcttcc tcaagttttt caacctgtgc ctgtcgctca
    21241 tcaatgtgct tagatttatc ggtcagactt tgctctttgc tatctagtac tttttcttta
    21301 cttgatagat tttcatcctt acgatcaaga gttagagcac gctctgccaa gcgcgtctcc
    21361 agctgtttaa gctcttgtct ttcagattta aattcctgtt caatttcttc acgatacttt
    21421 cttgcctctt cctttgcttc taaaagtaat tctttacgac ttgctttact ttcacgttgt
    21481 gctgtctttt tgatatgagc ggcatcggcc tttgccttgc cacgaatatc aacagcatcc
    21541 tgttcagcgt ttaaaagagt caactctgca gcttccttcg cagacttgag tctaatcgaa
    21601 ataagtgcat aacctaatat tacaccaatg aggccacaga caagtaacgt tatgatatta
    21661 attaacatgt ctttacctca ataatagttt agttttcatt aacagaaagc catctcttag
    21721 tctatcataa aatgaagatt tagacaattt aaaatccacc tacatttttc taaaatctag
    21781 tgattttatg ttatgatatt gataaaaata aaaaggagtt tcttatgcca aaagaagtta
    21841 ttgttgaaag ctttgagctt gatcatacta ttgttaaggc accctatgta cggctaatct
    21901 ccgaggaatt tgggccccag ggagatgtga ttacaaattt tgatgttcga cttgttcagc
    21961 ctaatcaggc tgccattgag actgccggtt tacataccat tgagcattta ttagccaagc
    22021 tcattcgtca acgcattgat ggaatgattg attgctcccc ctttggctgc cgcacaggct
    22081 ttcacctcat catgtggggc aagcatagct caacagatat tgctaagatc atcacgtcca
    22141 gcctagagga aattgctaca agcatcactt gggaggacgt tcctggcaca accattgaat
    22201 cctgcggcaa ttataaggat cacagccttt ttgctgctaa ggaatgggca cagcttattc
    22261 tcaagcaagg gatctctgat gatccattta accgccatgt cacctcataa aacgaaagcc
    22321 tctcttttct gctaatgtga aggaggcttt taatgtattc aaaaaggtgc caaaggcaag
    22381 gctcaatgcc cttaccttta gcacctgtga taactagagt atccagttca ggatcacacc
    22441 ttgtcttcta agcattaata gtctaagtcc tctgcatgcc ccttgccatt tccgacaaaa
    22501 tagcctgttt tgcaattcaa tgaaaagagg taggtgccat caggcttaaa catgttgtaa
    22561 tagccattcc cattgataat attgaccggc tctaggatat aatcattgcc tgaaatatag
    22621 ccccttgctt gtgaggtagc cacaatacgc tcaagcacac ctggattaaa ggcccaagca
    22681 gggtttcctg tatcagcaat catagcctga ttgtagggca cacgagacag gtcacgctgc
    22741 aatattgaag ggtcatagcc tgtaatgcca tacattggag ccactggagc tggtacagca
    22801 ggaacctccg gagctgcagg gcttgctggt aaggcagaag cagctggagt gctagctgct
    22861 tgggtagcag acctgcttgc tagctgctca cgacctgcct tgatgcttga ttgtagcaat
    22921 gaatcaagtt ttgcattacc agtggttagc gtatcactag ctaggtcatc aaaattagca
    22981 tcagctttga cctcagctgc aatcttttca ccattgacaa ttgcagctgt tgtaaatttc
    23041 ccattaaccg cctgaatagc tgttacttgc tttttcagcc cagtaacctt ttccttagcc
    23101 ttgtcataat aggctgtccc ttcaagcctt tttaaagcag tctccaaatt cggtaactga
    23161 tcaaaggcgc tattttttag ggttgtttta tcattatctg tgaaaaatgt cttgtaaaga
    23221 tcttcaaaag ccttagcatt agcctttgtt ttgttggtct gattagctgt tgatgctttg
    23281 ctccttgctt ttttagaaac agtagccttt gactgaggct tatgcttaga cagctgatag
    23341 atatggttga gggcaaaggc tgaggctaca agggttagcg tggctaacaa aatagcaaac
    23401 agaggctttt tctttttaga cctacgacta gcatagctat ctgataaaat actctctact
    23461 tctgcaggtc gctcgctaac tgcgtcatca gctagctgcc cagtaaaatc actagcagaa
    23521 tcagtagctg ccgctgaagt gtcagctcta gctgctagag gctcaatgaa tgaggtctca
    23581 ccggctggct tctcctctgt tgaagcctcg tccactggct caacatcaac taagccggct
    23641 ttgctgagct cctctctttg ttttttgata aagttatcca gacttgctgt atctaactcc
    23701 atatactttg catcaaactt ttgtgatgac acttcgttac gatgccgctt aatatatttg
    23761 tctaaaacac tatcatcctc ggtaatccct gcttttagct ctgagtcctt gcgtactgcc
    23821 tcaccgattg tcattttttt ggcttcatga agctccaaat tttggctttc tgcctctgat
    23881 tcaaatgctt tgcttttttc tgacacgttt tttacctctc tatatcagat tgcgctttac
    23941 cctctctcca taaaattgat acaaatcaac ccttagagta ccattataaa gcttacgttt
    24001 tttatcagct ttttgaccat atttttgttc aaaatgatca tcactcgtca aaataaactt
    24061 gctccaggta actaatggag caaagacctg taccatctca ttatacaaga tgtctactgc
    24121 tttgtcatca agcaaacgct ctccataagg aggatttgaa atgatgacac cgtttatctt
    24181 gtctgtacgg aaatcctgca agcgcatttg cttaaaggta atgatatcag ccaagccagc
    24241 ctcctcagca tttctcttgg caagctcaac catacgaccg tcaatatcaa agcctgaaat
    24301 atccagctca atatcataat tagcctcttt ttcagcagcg tcacgaacct tttgaacacg
    24361 atctttgtcc acccagctcc attcctcaaa ggcaaaggag cgattaaagc caggagcgat
    24421 attcattccg atgagagccg cctcgataca aaaggtcccc gatccacagg tgggatcaac
    24481 caagggctta tccggaaacc aattagacag cttgaggata gctgctgcca tgttttcctt
    24541 aataggagct cccccttttt ccacccggta gccacgctta aataggcttg agccactagt
    24601 atcaatcatc agggtagcct gatcctttaa gattgagacc tcaattttga actcagcccc
    24661 cacctcttga aggggaatat gctccggtct atgaaaatgc tgctgcaatt ttctgacaat
    24721 ggcttttttg gtaatggctt gaacacttgg ctcgttgtgc agggttgacc tgacacactt
    24781 agcctttgca ataggaaacc tagcacctaa gggcaaataa tgctcccaat ccaaggcaaa
    24841 tacgccctga aacagctcct caaagcttcg tgctgggaac tgacctacaa taatcttaat
    24901 acggtcagcc gctcgcagcc aaagatttgc tttagcaata gcttcaatat cgccttcaaa
    24961 gaagaccttg ccattatcta ctcggcagtc aaatcccaag gcccttaatt ccttacccac
    25021 aacagcctct aggccagctg ctgcagttgc tactaatgta aattgttctt tcatatgact
    25081 ctttctatcc taaccaaata aaagctagca tatgctagct taacctatta tgcaattttc
    25141 tataagccat gttttgttcc agaaataact aggtattatc tccttcgata atcatctgtc
    25201 tactgtttgt caacagtcag gatagcttgt tcgtttccaa ctatcccatg cccctaccaa
    25261 agtttgggtt gctagcttga ggggtttacc gcgttccact ttttacgttt ccataaaaac
    25321 ttcgtcactg tggcactttc agagctactc tggcatatca aggacttagc cttttcactc
    25381 gccgtaatgt gtcaaacaca tccctaggct tatttgttcg cctagcacaa acactaccag
    25441 catcacagcc ggtgctagca tggactttcc tcatagtatt gcaatactac gcgattatcc
    25501 aaaaattgca catctacatt actcaataat ttgctttcca aaaacctctt tttccagctt
    25561 gctaatgcgc tttagcatgt caaaattggt ggctgactgt gctactctgg ttggctgtga
    25621 taccgcctga gagctgcctg ctaaaggatc acgcacctga gccttagcct tttttaaggc
    25681 ttcattttca gcctttaggg cctcgatctg agcattgaaa tactcataat ccttgatgac
    25741 gttatcaagg aattcgtcga cctccttctt atcaaagcca cgcatactgg tcttaaattc
    25801 ttgctcaaaa atgtcctttg gactataaat tatacctgtc attctatact ctccaaacgg
    25861 tcaatctttt tcaaatatca aactttgata tcactactta tggtacagaa aaataaatta
    25921 aaaagcaagt atttaaatac cagtgatttt taaatatcac tagctactca tctgcaatgt
    25981 catttaaacg ctcaaagttt aggaaagaaa gggggtaaca gggctgctcc ttcatagctg
    26041 ctaccaaata gcttaggcgc gtttcgtgct cactatcata aaaaagatag gctccgtctg
    26101 tattgtgaat caaaaagtga tggtagctct ttagctgttt agggctttca tagctgggat
    26161 agctatattt gacaaaatca gtctcccgaa attgctgcag ctgctgctga ttgcgatcat
    26221 tccaagtgct gccatgcgtt tcaaaggcaa aaatagtcgc tgtctttaag gggtaggtct
    26281 ttttgaggtc attagctacc tctaaagccc actgctcaaa ccctaaattc ccagtaaaaa
    26341 taaaccagtc taccccctcc tcaagataag caatcagatc tctttctatc gcttttttga
    26401 taatggcaac tcttttatcc ttttcactaa agatgcccag ctcaaaactt cgatagcctg
    26461 ttacgagaat tgcagtcatt agatgttatc ctttcaaaaa tatgttataa tgtgaatgct
    26521 taaattatta ttaagtcatg atgttaggag aacaatggtt aactaccctc ataatcctat
    26581 tcgccaaaag gtgacccctc ttcaaaagca gcaaaagcac aagcaagtag actttgctaa
    26641 tcgtggtatg tcctttgaag catccattaa tgcaaccaac gcttattact tggccaaggg
    26701 cattgctgtc attcataaaa agccaactcc gatacagatt gtcaaggtag actatccaag
    26761 acgtagtcga gccaagattg ttgaggctta ttttaagcag gcttcaacga ccgactattc
    26821 tggtatctac aaagggcatt atattgattt tgaagctaag gaaacaagac aaaaaacagc
    26881 tatgccaatg aaaaactttc acgcgcatca gattgagcac atggctgctg ttttaaagca
    26941 aaaaggcatt tgctttgtcc tccttcactt tgcgacacta aaggaaacct attatctacc
    27001 tgccaaagca ctcattgatt tttatcagat tgataggggc aacaaatcaa tgccacttga
    27061 ttatatcaga aaaaacggct ttgaggtcaa gctgggagca tttccacagg ttccttattt
    27121 agatattata gaacaaaaat ttttaggcgg tgattacaat taacaatcca aaaatcctta
    27181 aattcctgaa gtatacatta ggtgctatcc ttagccttat cattgtgaca attaccttag
    27241 gtggcctttt gtttgcttac tatatcagca gtgcccctaa gctttctgag gcccagctca
    27301 aatcgaccaa ttccagtctt gtttatgacg gtaataatca tttgattgct gacttgggct
    27361 ctgaaaagcg tgaaaatgtt acagctgaca gcattcctat taatctggtc aatgctatta
    27421 tttctataga agacaaacgc ttttttaatc atcggggggt tgatctctat cgtatcttag
    27481 gtgcagcctt tcacaattta acaagcaaaa caacccaagg ggggtctaca cttgatcagc
    27541 agctgattaa gctagcctac ttctcgacaa acgagtctga ccagaccttg aagcgaaaag
    27601 ctcaggaggt ttggctggcc cttcaaatgg agcgaaaata taccaagcaa gaaatcctga
    27661 ccttctacat caacaaggtt tatatgggaa atggtaatta tggtatgctg acagcagcca
    27721 aggcttatta tggcaaggat ttgaaagatt tgtcctatgc tcagctagcc ttgctggcag
    27781 ggattccaca ggccccaagc cagtatgacc cctacacaca gcctgagaca gctcaaagcc
    27841 gccgaaatat tgtccttcag caaatgtatg ctgaaaagaa cattaccaag gctgagtacg
    27901 aagcagctat cgccacacct atatcagaag gcctacagcc tctccagcaa cgcgccagct
    27961 atccaaaata tatggataat tacttaaaac aggtgatcga gcaggtaaag gctgagacca
    28021 acaaggatat ctttacctct ggtctaaagg tttacacaaa catcattcca gaggctcaaa
    28081 aaaaacttta tgacatttac aattctgagg actatgtgta ttaccctgat gctgactttc
    28141 aggttgcctc aaccgttatt gatgtcacaa atggacacgt tatcgcccaa ttaggaggac
    28201 gcaatcagga taccaacgtt tcctttggaa ccaatcaggc tgtcttaacc gatcgtgact
    28261 ggggatccac catgaagccg atcacagact atggacctgc cattgagtcc ggtgcttaca
    28321 attctacagc tcaaacaact aacgactctg tctactattg gccggggaca cacactcagc
    28381 tctataactg ggaccggaga tactatggtt ggatgaccat tcaagctgct ctcatgcaat
    28441 cacgaaacgt ccctgcagtt agggctctag aggcggcagg tcttagctat gcacagtcct
    28501 tcctcagtga tctaggcatt aattatccag agatgcatta ttcaaacgcc atctcaagta
    28561 acaatagcag ttctgattca aaatacggtg caagcagtga aaaaatggct gctgcctatg
    28621 cagcttttgc caacggtgga ctctattaca agccacaata cgtcaataaa attgaattca
    28681 gcgatgggac cagcaaggtc atcgaaaata agggcaagcg tgccatgaaa gaaacaacag
    28741 cctatatgat gactgatatg ctaaaaacgg tactaaccta cggtacaggt actgctgctg
    28801 ctatcccagg agttgcacag gctggtaaaa ctggtacctc aaactatacc gatgaggagc
    28861 tggcacaaat tgttgagaca catggactat ctcctgatta cgtgggaaca atggcgccag
    28921 atgaaaactt tgtcggctac accaaccgat acgctatggc ggtttggact ggttataaaa
    28981 accgtatgac gccaatttat ggctacagcc tagaaattgc ttctcatgtt tatcgcaaca
    29041 tgatcagcta tctcaccggc ggctacagcg acgattggac catgccaagt gggctctatc
    29101 gtagcggcgg cttcctctac ctaagtggta cctatacaaa cagtagcgat tatacaagct
    29161 ctgtctacaa caacctctat ggtaataaca gctcagcttc aagccaatcc tcagatgagg
    29221 atacaactga agacagccac tcagaagcaa acgacagcac aacgtcatca tcagagcagc
    29281 aatcaagctc caccgatgat aagaaaacca actgataaca aaaaactggt tcaaatgttc
    29341 tgaaccagtt ttttcaatta tttggctaag gcacccatcg gatcccaagg ggcaagtacc
    29401 tgtggttctg cctcataggc tgctaattca tcagctgtta gtaggtcctt gcgaacaaca
    29461 atctggtaag tatactcgtc catccaagca tcagaagcaa caaagtatcc tttgtcacca
    29521 accttgtctc cccaagaatt ttcaaccttc catttgatag gcttaccagt atcatctaaa
    29581 tcaacacctg tcaaaaccat agcatgtgtc attaagcttt cgctgtaatc aaggcgacca
    29641 gccttgtctt ggctcaactg aatatccata cctgcctgaa aatcataggt attaagggct
    29701 agaatcccct tttgacgatc tgatacctga ccaacgtctg aaccaaacca aacggactct
    29761 ccagcctgca tttgcttaat agcaagctcc ttgaagcgct ccatatcaag attaaggtag
    29821 cgcacctcag gactgccaac aacattacca agcatatcaa ccgtataaga tttgccataa
    29881 ggcttatcag ctgttggggc gttgataaca gacacataat cagacagctt tagaccaaca
    29941 tatttttcat aaaatgcctg tggtgtgatg cccttatcag catgatagtg attatcctta
    30001 tcacgataag caaaatcaaa ttgacgaggt ggcaaaccaa gattcatggc taagaaatta
    30061 aagatttcct gaagtagctc ttctttttta gcctgtactg cctgatgatc agcaccagca
    30121 ctgatcacat ctcgaagaat ctgagcgtcc tgacgcaaga gcttattgag gtattgattt
    30181 agctcacgac tattgcttga tgacacagac tctgggtaga ctgattttgg cacaacaccg
    30241 tatttttcaa acagggctac aaccatgtcc cactgaccac cgtcttgctg cggaacgtcc
    30301 aaaagaaact taaccctacg gctagtcaag gcttgatcag cagttgcaat cacctgttcc
    30361 ataaaccagt ttgatttttc gtatttgtcc cagaaaaagg tgtgtgcttg tgacaactca
    30421 aaatcttcta atttaaattc tgaaataagc ttatggcgaa aggtgtttaa ggctgcaaac
    30481 atccagcaac gacctgaagc cttttgatta gagaccttat cctttgtcaa gtcaatggaa
    30541 aagacaaaat cattgtcgat ctcactttgt cttgtctcca aggatttaag caagccattg
    30601 tgagtgatgg cattttcaag agctaaatat ttagcattag cttcataatt agcatatagc
    30661 tgttctgtaa atgtctctgt taatactgac atcattttcc tccaaagata ataaataaca
    30721 acacctaaaa ataaagttga cagaaaaatc cataaatact gtcaatttca ttttcaagga
    30781 ttacttctat tatagacctt atttgatatt cttcaagtaa aaaaattagg ctaacttaat
    30841 tttttaaagc taagcagcag ctttccaata accagacaaa aagccatctc aaaagacgac
    30901 aaaacctgct ggactttgag cacctaaaca tgtcatatgt ccacctcagc atgaactcaa
    30961 agaagctagc tgtgtctggc tatgacttca gtttaatcat tagcttgcct tagccacaaa
    31021 aagaatcgtc tccactgtag caaaagtgct tgatataaca ccatcggcta agtcaagggg
    31081 cccctgatag ttaactgaaa catatggcaa agctaaaacc aaagacttct tctccttaaa
    31141 gcctctggtt tttagttagc tgagcattct cctttatctt ggctgcttta agatagggac
    31201 aaatcaacaa ctaccccaat cccatttaca aaaaagccct aagtcagagc cttcataggg
    31261 ctaagggtga gggaagctct taggcaacag ctactggatt tatgcctaat agaagctcct
    31321 gtccctcctc acctatttaa aatagcattg gtttatctat agcctgtgta ggtttgagga
    31381 tcacttccaa aagtcatcaa aaatagtaat tggcagatgg cgcttgtgct gccctttatg
    31441 ccaccagtct tcaatccttg cctgagcttc agcggaaatc gtatgcccct ctaagtaatc
    31501 gtctatctct tgataagtaa cacctaatgc tacctcatct gcaagtcctg gcttcttatc
    31561 ctctagatct gctgttggca ccttctcata gaggctgggg tcagccttta gcacctttaa
    31621 caaggcctta ccctgccgct tagtcaagcg aaaaaggggt agaatatccg ctccgccatc
    31681 accaaactta gtgaaaaagc ccgtaacatt ttcggcggca tgatctgtcc caatgacagc
    31741 accagctgtt tgaccagcga tagcatactg actaatcata cgctgacgtg ccttaatgtt
    31801 tcccttatta aagtcagaaa tctcaagccc tgccgcctct aaggctctta gctgaccatc
    31861 aacagcctct ttaatattaa ccgtcaaggc ttgatcaggt tgaataaatg ctaaggcttt
    31921 ttgtgcatct gcctcatctg cctgaacacc atagggcaag cggacagcga taaattggta
    31981 ctgctcatca cctgtttcag cgcgcagctc ttcaatcgcc atctgagcta gctttccggc
    32041 taagctggaa tcctgaccac cagaaatccc taagacataa gtctttaaaa aagggtgctt
    32101 taacaaataa gcctttaaaa aatcaaccga ctggcgaatc tcctgcttag gatcaattac
    32161 tgctttgacc tcaagctgac gaatgatatc ctcttgtaat gtcatatcaa atcactcctt
    32221 ttacaggctt ccttgcggat tttgtcaata agatgcatct tattttgcca aacatcaagc
    32281 gcaagatcca cagggtaatg ctgcggattc aagacacgct tatattcgtc ccaaagctta
    32341 tcaaattcct ttctagcata agccttgatg tcttttaagc ttggcagctg ataaacgagc
    32401 tttcctttat caaaaatatc tactagcaaa ggaacagcat caaaatctct gacggtttta
    32461 ttaatgtagg tataagtcgg gtggaacatg tgaatttcct ctaggtcatt gacattaaca
    32521 cctgtaaagg tgatgtaatc gccttctgac ttgccctttt cgcggctggt aattcgccaa
    32581 acctgctttt tacctggtgt tgataccttt tctgcattat ttgatagctt gatagtatcg
    32641 cgcatggtac catctgcctg ctctatcgaa acaatcttat aaaccgctcc cagagctggt
    32701 tgatcatagg ctgtaatcaa ttttgttcca acaccccaaa cgtcaatttt agctttttgc
    32761 attttcaggt tgagaattgt attttcatct aaatcattgg aagcgtaaat cttagcctct
    32821 gtgaagccgg cagcatccag ctgctggcgt acccttttag ataggtaagc aaggtcacca
    32881 gaatccagac gaacacccaa gaaattaatc ttatcaccta attccttggc cacacgaata
    32941 gctgttggga cacctaccct caaggtatca taggtatcaa ccaagaaaat acaatccttg
    33001 tgcacactgg cataggcctt gaaagcatca taatcattac cataggcctg taccagagca
    33061 tgtgcatgcg tgccagacac aggaatgtca aaacgctttc cggcacgaac gttactagtt
    33121 gcgtctgctc cgccaataat ggcagcacgt gtcccccaaa cagcagcgtc catctcctga
    33181 gcgcggcgtg tcccaaactc taaaagtggc tcatcttcaa taacagagcg aatacgagct
    33241 gcctttgtag caatcaaggt ttggaaattc acgatattca aaagagctgt ttctactagc
    33301 tgacattgac ctaaaggtcc ctcaacctga acaataggct cattggcaaa gaccaagtct
    33361 ccctcttgtg ctgagcgaat cgttagctct aaacgaagct ctctgagata ggtcaaaaaa
    33421 gcagggctgt agcctagctc cttcaaataa gccaaatcgg tctcagaaaa ggtcaattgc
    33481 tcaaggtatt ctacgattcg ttgtagacca gcaaaaactg catagccatt gttaaaaggc
    33541 tctctacgaa aataaacctc aaagacagca ttacgattat gaatgccctg ctcaaaataa
    33601 acctgcatca tatttaattg atataaatca gtatgaaggg ttaagctatc atctctgtac
    33661 atataagtaa ctccttaaca taattgttat tattatacca tatttttggc atagacctgt
    33721 aagattcaac taaaatcctc tgctcaagct ttctaaaaaa gaagccttga gctgctatta
    33781 agcctgacat attttttgcc agtaccttcc taaaaagtct atagcacaag ggcttatggc
    33841 tttttaacaa aagcagtttc agttgatagc attcataaaa aaagattgaa gaaattgacc
    33901 aaaatagccc ctttcttcaa tctatttaac tcacacctta gccttttaac gcttttttac
    33961 acttgagctg actgtagcag ccaaagacta gaatccaaat gctagcacca attgccccga
    34021 tataggtgga cttctgtaaa aacagtgaaa taaaaacaaa ggcaaaaaag gctagggtca
    34081 atggtgttgt tagctgataa cttggcatca aataaccatc tggcataaag tcactggact
    34141 gacgatattt ccaatgcgca agcatggtca aagcataaat cgcaatataa acaccagatg
    34201 atgaggccgt aatcagcgaa aaggcatctg caacaccggg caggatatta atcaaggccg
    34261 acaccccaac agcaacagca gaagcaataa tagccctact tggtacccct tgacgagata
    34321 gggtgttaat cctcaaggct ttagtaagag catttggggt ctcattagcg atttgataca
    34381 aatgccgacc tgtcgaatac agggtcgaat ttagggctga tgctgctgat gttaagacca
    34441 caaaattaat taaagcagca gcccatttaa tcccaatcag cttaaagacc atcacaaagg
    34501 gagactcgtc cgtaggcaac tgataccaag gcacaatcgc cataatagac accaaagcac
    34561 caacgtaaaa aatgacaatc cgcatcggaa tctcttggat ggccttgggc aagacctttc
    34621 taggatttgc ggtctctgag gttgtaatac caacaaattc gatggcctga taggcaaaga
    34681 aaaccatctg aaaggccatg aaaaatttca acttcccatt cggaaatagt gaaaaatgat
    34741 ccacaatatt ggcaaggctg gcatgaccga catgcgtttc aaagcccgtt agaaccataa
    34801 aaacggctgt tgcaatcaag gctaaaatcg caacaatctt aatcatggca aaccaaaatt
    34861 cagtctctcc aaagacccgc acagcaatta aattgatgga gctaagcaac accaaaaaaa
    34921 cgagctgaat cagccaagat ggccaagcag gaaaccaaaa ctgaacatag gaggcgacag
    34981 ctgtaatctc tgccatgcca ataaagatca gggaaatcca gtaagaaagc ccagaaaaat
    35041 agccccagcc tggcccaata tattttgtaa tgaaattgat aaaggtatgc tgatccggat
    35101 catagtatag catctcacca atagcccgca tcatcaaaaa cataaagaca cctgtaatca
    35161 tgtaaacaaa gataatagac ggacccgtta aggcaataga acgaccagct cctagaaaga
    35221 gacctgttcc aatagtgcct gctatcgcaa tgagctgaac atgtcggttt tgcagccccc
    35281 ttaccatgcc attctcaagt tctttagtgc ttttagcttc ttttgtagac atttgactct
    35341 ccattcaatt aaaaaaacac cactattata tctgtttttc agaaaatgtt caactttctc
    35401 taaggcttgc aaactaaaaa ggccaaccaa gcctttttag cgttaacctt tttaagatga
    35461 taggctttca atgtaatggt agacgccttg accggcaatg gcaccatctc caactgctgt
    35521 tgtgatctga cgcagctgct tttgacgaac atcaccgaca gcaaaaatac caggaatact
    35581 tgtcttcatt tgatcgtctg tcacaatcca gccctcttga ttggtaatgc ctagctcaga
    35641 taccatttga gtaaccggaa tcaagccgac atagataaag acaccaccaa agtcatggct
    35701 agtcacttga cctgttttga cattttcaat cacaacatta gagaccttaa tatcgtttcc
    35761 ttgaatctcc ttgacaacag aatcccagat aaaatcaagc ttttcgttgg caaaagcacg
    35821 ctcctgcaag atcttttggg cacgcagctg atcacgacga tgcacaatcg ttactttctt
    35881 agcgaactgg gtcaggtaga tggcttcctc aactgctgaa tctcctcctc ctacaactaa
    35941 taactcctga ttgcgaaaga aagcaccatc acagaccgca caataagaaa cacctcgact
    36001 ggtgtactcc tcttctccag caacacctaa aagacgatgc tttgctcctg tcgcgacaat
    36061 cactgtttta gtatcgtagt gcgtatcttc tgtgtacaca cgcttataat caccacaatc
    36121 ctcaaccctt tgaacaatgc cataaatgtt ttcaacctta aatttttcaa gcggctcata
    36181 catctttaac gatagctctg gtcctgaaat gtgatcatag ccaggataat tttcaatatc
    36241 tgatgtgtta ttcatttgac cgccaggtgc cccctgctca ataatgccaa ctcgtaggtt
    36301 actacgtgct gcatataaag cagctgtcat accagcaggt cctgatccaa taatgagtgt
    36361 atcgtacatg ggttaactcc tcttaatagt cttgtcatca ttttaacaat agctacatcg
    36421 tattgcaatt atttcgcctt caataccacc agaatgctca taaaggcaaa ggacaaaatc
    36481 ggaatcgtca aaatagcaac cataatcatc tcatataaaa atgcctgtct ctggagaatg
    36541 gttttatcct ttttggtcac agcacgccat aaaatccaca aaagacaaag catgaccatc
    36601 gtaatagctg ctaacaacag accttccaaa taaaagcgaa aaatttctac taacatcttt
    36661 atctacctga ttaccataac cttttttcat ggcagcttag cttttaagca catacaagaa
    36721 aagcctagcc tacctagacc tttttattat atcaaaagcc ggcttttaaa tatacgtttt
    36781 tgcatagttt gcaaaaaatt cctttgttct tgcttcctta gggtgtctaa agatctgctc
    36841 aggagctccc tcttcaagaa ttttcccctt gtctaaaaaa agcaccctat ctgcaacctg
    36901 ataaacaaaa gccatatcat gactcactaa aatcatcgtt tgacctgcct tggcagcatc
    36961 aataatagac cgttcaacct ctccaaccag ctcaggatcc aaggctgagg taggctcatc
    37021 taataatagc acatctggct tcatggctaa agcacgcgca atagcaaccc tttgcttttg
    37081 accgccagat aaatgacgag ggtaatggtt ttcacgatca gacaagccaa ccttagctaa
    37141 ttctgctcta gctatgtctg ttgcttcttg gtcagacagt tttttaacta tttttaatcc
    37201 ttccttgaca ttgtcaagcg ctgtgcggcg ttcaaagagg ttaaattgct gaaagaccat
    37261 cgctaatttt cgtctaagcg ttagaatgtc ttcttttgtg atgtgttcaa agtcaactgc
    37321 aaagtcatca atcgtaatac ttcctgtatc tggctgttca agataattca tgcttctaag
    37381 gaaggttgat tttcctgcac ctgatgcacc aaccagagct ataacctgcc ctttttcaat
    37441 cgtcaccgtt aaatcgtcta agatcttttg tccagagaag gacttggtta aatgagttac
    37501 cttaatcatt agcgcaattc tcctatcttg ctattatttg ttgggattgg tgctttgata
    37561 gccatgttat attcaattag gcgaccagcc tgttctatca aaatactaat gccccaataa
    37621 actaaggcaa ctgagatgta acgttcaaaa taacgataat ctgctccccc tagaatctgt
    37681 gcctgtgcaa acatttcaac gatacctgca ttgaaggcca gagaggttcc ctttgtcagg
    37741 cctatcaacc cattaatcaa ggtcggtgtt gccacaacag cggcatttgg aatgataact
    37801 cggcgataaa cctgagcaga ggtcattcct aggctcttag cagcctcaat ttcgcctgtg
    37861 tgaacagatt gaatcgcagc tctaatggtt tcactcgtat aagcagcttc attgaaggca
    37921 aaggcggtaa tcgcaaagat agaagccgga atagcgttga tattccaatc aaagccatag
    37981 cgttgattta agaatttcag aaaaagagga ataccatagt agctcagcat tagctgaacc
    38041 aatatggggg ttccacgcaa aaagctaaca aaaaccgctt gaatcggata aagaatgcga
    38101 accctgttga ttttgacaat ggcaaaaacc aaggccaaaa aaagacccaa ggcagcacca
    38161 gctatcgtca aaccaagtgt gattggcaga cgcctgataa tatctggaat ggcatcaaaa
    38221 acagcatgcc agctaaacag cttcccttct gggatcaacg agatgagctt gtcataccaa
    38281 gcccacccac ttgttaaaaa cgtagatgtc atgtatcgcc cctttatact ggtttgtctc
    38341 aatattttca ttttaacatt cttgagatgt catgtaaaat agtaaatccg catgataatg
    38401 ataagaaaag cctatcgcag aggataggac tcaaacaaag gaaaaaaact ctttgaaata
    38461 ccgttaacag tagcctcttg gagctaccaa gcttgaactt gagccgaact ctcaaagcct
    38521 ccaagtggct aattctcaaa gaatatagcc actggtacaa gactaacaat cagctactag
    38581 gccaaaaagg tcaaaagctt ggctagctgg cacagctaac tgcctcaaag gctaggtcaa
    38641 cgaaagattg aagcctgccc agggcttgag ggcttttagc cctgtcaatt aattgacctt
    38701 ggagataaag tctcctccca aaaatgcttg gctgagcttt ctgagctgac ctgatttttt
    38761 aagcttagcc agccttttgt tgacaaagct ctgtagagcc ttaccctttt gatcattggc
    38821 aaacacataa tattccaagc catccttagc agtatcagcc tgctccttga gctttgtcac
    38881 atgcacatca aagccttgct cctcagctac ggttgttaga gaaatagcgt catagaaaag
    38941 aaagtccagt tgaccattct ccagcagctg cagcctttga gtaaatgggg ttgactcaga
    39001 agcataggta aggtgaatag gcttttggtc aggatgggat tggttccatt tttcaaggat
    39061 aagcatgtaa ttggagccag ctattccttg ggttttcttt ccagaaagat cagctaagct
    39121 tttatactgc tgcttaccct ttgttgccag agcataatgc gaggccgaaa tagggcttga
    39181 aaacaaatac ttttcagctc tttccttact atagccaaaa ttattggccc caatctgata
    39241 acgacctgca tcaataccag ccaggatcga tggaaaagga accacctcta tgcttaaccg
    39301 atactttttg gagcctttaa aaaccctttt tagaacctca atatcatagc ctgtaacgct
    39361 atgcttcttc ctataggtaa agggcttagt ggcagcatct gttgctactc tgatcacctc
    39421 tttttgacga gctgtgacct catggctagt cacgactgcc aagagtccta gacttgctag
    39481 caaaaaaaag agtgctcgct gtaattgttt tgtcatacca tactcctatc tcttatacag
    39541 tagccatttt aacaaaaaat gataaatttg aataatatca tttctctatc aaggcaataa
    39601 gaaaatagta tcaaacaagc aattaaaaca gcacattctt catttacctg atcatggatt
    39661 aaccacaaca gacaagcttt agctattagc aggctgccta agccaaaatc aacacctcaa
    39721 gctttcaact gactgatgta aaagctagta gtcacctcta caagaagaaa aagaactgtt
    39781 tgtgtcattc aaccagtagc acccttctta actggtcatt cctatccagc tctactacta
    39841 ggctgtcagt taacgatcag aaaaaaagtt gacctatctg ccttatgaag cctagaaaac
    39901 tagctttcat tctgtttaac attagaaaac gagtaaatag tttaaaataa atttttatta
    39961 ttaaacttta actgttgcta tattaatctt tttacattat aattaagtat aaggaggttt
    40021 tctatgaaaa aggcaatagt atcggttact ttgttaacag tagctgtttt aagcttatca
    40081 acaagattta tctactccac tgattattct gatttaaatc ataaggagat ggcacgtctt
    40141 atccagtcaa gaaaacaacc agtaattaag tatcatgaca atgtaaccat taataaaatg
    40201 attacttacc tagctcaggc taaaagagaa ggcattctga cagagacctt cctcatgaat
    40261 tatattttcg ctggagaggg tgagtacctg actaaaaatt caaggattat tgccgatcct
    40321 gacggagggt attggagtat cctagaaggt tatgagggag atggcggtgt taagactggt
    40381 attgacggcg tctcagagct caatatcttt agtccagaat ctaccagcat cggagagctt
    40441 caagaagcgg tgctagcctg gtatgaggct aataagtaac cgcagcttag ttaaccgact
    40501 gcttcatata atagctaata ttagctaatc ataggcctta taggcattga aatggtcaga
    40561 cccatgctca atgcttataa ggttttttag tgcttaccat ctaaccaaaa ccatagcctt
    40621 cagagagaca ttgagctgaa caagcaaaaa agaggagcaa gctcctcctc aaacattaat
    40681 acaccttaat ctacactccc acagaggaag taatttaagg ctggtgtgtc aaagcgtatc
    40741 aacccgttaa tttcaatcac tattctgaca gccaaaggtg cggctttagt tgttaatagc
    40801 tggttttagt tgccacgctt caaagatagt tgctgtaaca attgaagtag gttcgacaat
    40861 ttcaaatgta acaatacttt tatcacacct tttgcgggag cgtagattga aatccttgca
    40921 cgcaacgaca ggaccatttg acatgggaca ctgaacagag ttgaagcctt taaaaacaat
    40981 ccctaaacag ctttgggacc taatcacagt tccttgactc agctctgtca aggattctgt
    41041 tcatatcagc ttagaatgat cgctaaaaac tttttgatct aatttttctt gaacggatga
    41101 tctttaccaa gcacctgtct taaaagcttt gctttctgga ctgacgctct gctcgtccct
    41161 tggcacgttt ttctgctcgt cgctgcttgc gccgcttttc atcaactgcc cattgaattt
    41221 tctttttata gcccggttta atttttttct tttttttctt aaccaggcca atcatttcag
    41281 tgtctaattt ctgataagct ttttcacgat tctggcgacg atcacgatcg taagtatcct
    41341 gaaactcacc attttttaaa acctttggta taaaggtaat gcctagcttt tccagctcct
    41401 tgatatcaga atcatcactt ggctgataaa aggtaatggc tgtccctggc aggccgtttc
    41461 tacctgtccg ccccacacga tgcacaaaaa aggataggtc ttgaggaatg gcgtcgttaa
    41521 tcacatgact aaccccctca atatcaatac cacgcgccgc caaatccgtt gccacaatgt
    41581 attcaaatgc caggtttttg acttgattca tgatacgctt gcgctctcta ggaggaatac
    41641 ctccatgaag cttggctgcc ttcataccat tagctgctaa aaaggcatgt aagtcatcag
    41701 ctctctcctt ggtattgaca aaaagcatgg ccagataagg ctggatagcc tttagagtcg
    41761 ccaaaatttg ctcattttta tcgcgtccct tggttgataa cagccagttg tcaatcgtat
    41821 ctgcaataac ggtttctgtc ttgatctgtt caatgacagg attggtcaaa tacttcctta
    41881 aaaagggctg tagcttttgt ggaatggttg ctgaaaatac aagtatttgg atagtctttg
    41941 gcagtgctga agcaatctta tccacagtgc ttaaaaagcc catatccatt gtcatatcag
    42001 cctcatcaac aacaaaggta gaggccttat gaatggctaa atctcctgac ttgactagat
    42061 catagatacg acctggcgtt ccaatgacaa gctggggctg actaagcttt aacttgtcaa
    42121 gctgacgctg cttgtctgtc cctccaacgt aattagcaat acgaatctcc tgcttagaat
    42181 gcttagcaat ttgcctgctg gcctcaaaaa tctgtgttgc tagttcccgg ctaggtgctg
    42241 taatcacagc ttgaacctct tctttttcct ccttgagctt ttcaaaaata ggcagcaaaa
    42301 aggtatgcgt ctttcctgag cctgtctttg actcacccac taagtctcgt cctgtactga
    42361 caatcgggat aagacgctgc tgaacctctg ttggctctac aaagccaagc tcatctaggg
    42421 cctcttgaat ataatgctta aagtgataat cgtgaaatga cattatttac ctcgttttct
    42481 ttctgataat actattagtg cttgagatga gcaaaaggcg gtgcctcaag cactgcccca
    42541 gccgcttaca aataaagaat cgctaaaaca atgagactgg ctacaagacc aagagcccat
    42601 aggaaggcat caaccttcca ttcagaccac ttggctgctt taccggacaa gccgcctaat
    42661 tccagatgat gatgaaaagg agtcatccta aaaatccgac ggccttcacc atattttttc
    42721 ttggtgtatt taaagtaagt aacctgaagc atgactgagc ttgtctcaag aacatagaca
    42781 atcccaataa ccagcaaggt ccattcctga cgaagcgcaa tagaaatcgc tgctagcatt
    42841 gctcctaagg ctaagcttcc aacatcaccc ataaaaattt tggccggctt atggttaaac
    42901 aagaaaaagg ccagcaaggc accaaccatg atacctatca agagcaaaac atcaaattgt
    42961 ccctgagcat aagcgataac accataggcc agcaggctaa tcacaacaga taccgaggcc
    43021 agaccatcaa taccgtctgt caggttgacc gcatttgaaa agccaaccac ccaaaaaaga
    43081 acaaagcata ggtataaaaa gcccaaatgc caatgataac caaagacatt aatcgcatca
    43141 ataccacttg gcatgacgtg tatcacataa aagaccaggc ctccaacaat ctgaaacgtg
    43201 aatttttgct tggcagtaag gccttcatta acctgcttga agatctttaa gaaatcatct
    43261 aaaaagccta tgatcccgta aatcaataca atcaacaaga tccccgaaat caagcctagg
    43321 ctttgtccat ctcgaaaata gactaaagca aacacaaagg ataagcttgt agcaacaaga
    43381 agaaaaactg ttcctcccat tgtaggtgtt ccagccttag ccaaatgctg cttaacgtcc
    43441 tcatgcatct gctgcccccc aatttttttc aactggtaaa gccttataaa gtgaggcatg
    43501 gcaagggcag tcacagcaaa ggctatcaga cctgctagaa tggttaaaaa catgttaatc
    43561 tcctaaagtt atggtaattt ttttgacttt tttgagcgct tttccgacat caacgctctg
    43621 tttaacgaca cgtcccgagc ttgatccctt gtacttgata tcaatgccag tccatttagc
    43681 aaaggtagcc acattagcct tagtccagcc gtacatatca ggcatctcat caaaatgatt
    43741 tgataaaatc agaagctgtt ggttagcagc tagattggtc cctgcctttt tagatacctt
    43801 tttaatcttg ctgccattgc caaggacaat agggtgaacc agatttctgc gtagctcatc
    43861 agctgatttt cctgtatctt ggccaacaat atcaggcaac tgataagtag cctcgtgact
    43921 ggtatctaca gcaaccggct tgtctaaagt atccttcatc aaataggctt cctctaaaac
    43981 agggttgata atatcctgcc aaaacaccat tgcccaatgc tctgggtgct tcagtgtgac
    44041 atacatcaga aaatcaggct catcagctgg caccatagca accaccgaat aaatatagtt
    44101 tgtcaagcca ccatctaaat aacctgtacc gtccttagtc gcaatctgcg cagtccctga
    44161 cttgacagca actggtaatt gaccaacctt aaccactgga cctgatgatt tcaaatgaag
    44221 ggttccaaat tgtgggtcag tcccaacgtt aatcatgtat tttcgtgttt cactggcagc
    44281 cttttgggac accggctttc cgacaatctc cttgtctgac acccggtaag tatctgtatt
    44341 tgggtcataa atgcgactaa caaattgagg ctctagcatc acaccgtcat tagagatggc
    44401 tgtaaaggct ctaagcattt gaatttgcgt caccgaaatc ccctgaccaa aagcgctcat
    44461 tgcttgggta acaatattat cagaagggaa aatacctggg tcttcatttt ccaagccaaa
    44521 gcgtgtccgg aatccaaaac ggaatttagt taggtagttc atccatttgt catttcccat
    44581 tttttgctct agcttggtca tgccaacgtt acttgaaaac gaaaagcctt gagcataggt
    44641 catgtactgc cctgtagaaa tcccttcgtt aatcgcccaa tcctgaatgg tagcatcagc
    44701 aatggttaag ccattcgcat tgctaaaggt ctcatcagga ttaaagacct tctcatcaat
    44761 agcagctgcc agagtcataa ccttcatggt tgagccgggc tcaaactgcc cctgatggag
    44821 aatattttgc cagctatagc ttttgctgtt tagcccctcc aaggtgtctg cattataggt
    44881 tggtctttga gtagtcgcta agatttcacc agtcttagca tttactagag tagcactagc
    44941 aagctctcct tgcgccttcg actgaaagac gtccatttgc gtttctagaa aggtttgaat
    45001 aggctctgac agggtggtat aaacgtcctt accatcaact ggctttttca ctgtctttcc
    45061 tgttccaagc agggtattac cgtttctatc cttttgataa gtgatgattc catcttcccc
    45121 agataagatg ctatcaaagg ccgcctccat gcccatcttt ccaactaggc tcttggtacc
    45181 gtcctccttg ttttcctcaa gtgaagcaag accaatcagc tctgaagcaa aggtcccatt
    45241 tggatacata cggctaggac ttgctgaaaa tgcgatcccc ttgattttag ctgcctccat
    45301 agccttttgg atcgttgtca tcgtgctata agaaatacct gagccagacg gaccaaagga
    45361 aacctgaaaa agaccttttt gcttaagctg cttaataacg tccttttcct ccatacccag
    45421 ctgctccttg aggatttgag caaccttgtc atactgagac ggttgaacaa aaagcttctc
    45481 gccagtcgct gacacaaagg acttatcaag aatggcataa atgctatagg tcgtcgagtc
    45541 cacagcgata gctgtgccat tgcgatcata aatcgtgcct cgcttggcct gaacagaaac
    45601 cgtctcttga taaacctttt tggctccatc tgatagctta acaccgaatt tctgatccgt
    45661 cccgataatg atcataaaat taatcataaa gatgaagaaa ataaagatgg ttaagagcat
    45721 catgttttgc cccaccctca agcggttctg aacaggtgtc tttcgatcac gaaccacata
    45781 atctaaaaaa tatctttgcc attttgtcat agcttactcg accttcttaa tgttatcatt
    45841 tcggttacta agccctgctt tgccagcaat atcaacaatg cggtcacgtc gcgacagctc
    45901 attaacctct tgcttggcat tgttaagctc tgtcctttta tctgagatct gcctattgag
    45961 ctgagtgata tgctgctgga gctgcaattt acggctttgc aggtaaataa tgcttacagc
    46021 catcgttact gctgtcagga taagcgtagc ataaaaagcc ttctcaaccc tcgagaaagt
    46081 tctaattctt ttttgcaagg cttttgaaac tgcctgagtt cttttttcat taaccataat
    46141 ctatttccga acttttcttg cgactcgtag cttggctgaa tgtgccctat tgttagccat
    46201 tagctccttt tgacttggta aaatcggctt acgcgaaacc aattcaagct taggcttgag
    46261 ctcatcaggt ataaagggaa gtccctttgg agcatcagct gtgcttgctt ctttaaacaa
    46321 gtgctttgtc agacgatcct ccaaagaatg aaaggtaatc actgagatac ggccatcaag
    46381 ggctagcagc tctatcgccc gctggataga cgcatcagca gcaccaagct catcattgac
    46441 ctcaatacga atagcctgaa agatttgctt ggctgggtgt ccttttttct tgagctcctt
    46501 ggctggctta gctgatttga tcaatgctgc cagctctgtg gtggtgctga ttggcttaat
    46561 ggctctcgcc tgctcaatct tacgagcaat ctgctttgag aacttatcct caccatattt
    46621 aaaaaagatc cgaactaagt cattgaaatc ataggtattg acaacctcat aggctgtcaa
    46681 agccgcctgg ctatccattc gcatgtccaa gggagcgtcc tgcttgtaag aaaagccacg
    46741 ctctctctca tctaactgcg gactagaaac ccctaaatca tacaaaatcc catcaatctc
    46801 tgtaacccca tgctccagca agcgtgcctt aaggtgtcta aaattgtcct taataaaggt
    46861 cacctgtccc ttgtcaatat agggcttgag ctgctcctgc gcgtgatcaa tagccttttg
    46921 gtcctgatca aagcaataca agtgcccctt atcaccaagc agagacagca aataagctga
    46981 gtgcccagag ccaccaaggg tcgcatctac ataaatacca tctggcttaa tatccagcat
    47041 atcaacagct tcatgaagaa gtacagttac atgatgaaat tcgtttgtca tagctctaat
    47101 tgtaccatac ttcaaagggt ttataaatca aaaagtaaga gaaaagggct ttcaaggcct
    47161 aagaaagtcc ctctttatct tacttttttt ggcttagcta tccttgacat caagatgact
    47221 aagagcttgc tgcacagcct catacagcag ctcagccgat tcgagcacct gcttggtctc
    47281 ctttaacacc cgaaaatctg tcaccgaatt atctagccaa atatcaaaga tcttatcctg
    47341 tcttgtatga gataagctag aaggcaagcg caactcacta accttcagct ccttttgata
    47401 cctacagacc agatttctca cgtcccctag gctctcatta atagcactga ttttttgcct
    47461 ttttacccag cttgttagta tcccattgtc gaacaaatca aaaaatcccc acctcttaag
    47521 ctctttcaat gcctcaatga cagactcaag cttaaaagct aatgtcttta ggtctcgtat
    47581 ggtttcttgc ttctttagat cccttgtcat aagcctacct ccttagcagc tagctccgaa
    47641 tctggccatt tccattgatc aggtatttac tgctggtcaa ggcctcaagt cccatcgggc
    47701 cacgagcatg cattttttgt gtggaaatgc caatttctgc tcctagacca aagacaaagc
    47761 catctgtaaa gcgtgtcgag gcattcacat aaacagctgc cgagtcaacc agatcctgaa
    47821 aacgctctgc agcattgata ttagctgtga tgatggcttc tgaatgatga ctggtatact
    47881 gattaatcca agaaatagct tcatcaagag aggaaaccag atgaacagac atgatataat
    47941 ccaaaaattc agccgcataa tcttcctctg tggctaatac agccttgcta aacaaggctt
    48001 ttgcctgctc atctgctcgc cattccacct gctgaacctt gctgatggct gcttcaagca
    48061 tgggaataaa ggtcgctcct accttctcat gaataatcag gctttctgca gcattgcaga
    48121 cgcttggtct ttgcgtctta gcattaatca caaccttaac agccatctct agatcggctg
    48181 cttcatcaac ataaatgtga acattgccaa cccccgtctc aatgactggc accttagcct
    48241 tttccttgac cgtttgaatt aatctggcac ccccacgagg aatcaagaca tcaatataat
    48301 ccgttgcctg catcaattcc tcagctacag catgagaggt atcctcaacc agcaaaacag
    48361 catctggcgt aatagctgat gcctctaagg catttctgat aagcctgacc aaggccatat
    48421 tagagtagag agcatctttg ccacctctaa gaataatggc attattggtc ttaaaggcca
    48481 agctaaaggc gtcaacagaa acattagggc ggctttcaaa aatcatcgca ataacaccta
    48541 aaggcacacg cttttgggtt attttcaggc cgtccagatt tgtatagccc ttaatcactt
    48601 cgccaatggg atcagccaag tctgccacct gtctgacgcc ctgagccatc gcatggatac
    48661 gatctgctgt caggcgtaag cgatcgcaca gaatctctga aatcccatgc tcagccgcct
    48721 tagccagatc cttggcattt tctgtcaaaa tcatatccgt ctgggccact aattcctcag
    48781 ccaaaaaggc aagaaattga tttttatcct tcgttgtcaa ggataccaag gccctactag
    48841 ctgccttagc cctttgtcct agctgttcta ttgtcatcac gcgtcacctc tttctatctg
    48901 tttaaaccaa gtgcctagct tttctccctc caagaccctt aaaatgtctc tagggttggc
    48961 accattcatc aaaatcattt gcccctgatg ctcaaacatc atctgggctg attggatctt
    49021 acttagcata ccaccagttc caaatctgct gcctgcaccg cctgctgagg ctataatatc
    49081 ctctgtaatc tctgtcacat gactcctcaa gcgcgcgtcc tcatagatgg ttggattctt
    49141 atcaaacaaa ccatcaatgt ctgatagcat aatcagcaaa tcagcccttg taatacgagc
    49201 tacgatagct gataagcggt cattgtctcc aaattttgtt gaatgatcca tctcatcaac
    49261 actaacagca tcattttcgt tgacaatggg gacaatccct aaactaatca ggctttcaaa
    49321 ggcattggtg acatttgcca gactttctgg aaaaacaacc acatcacgtg tcagcaaaat
    49381 ctgagacact gtcgtctgat agtgggcaaa aatttgcgaa taaaggctca tcatagcaac
    49441 ctgccccaca cttgaaacag cctgctgctt ggcaagctga cttggtcttt tggccatttt
    49501 caacaggtca agcccaaagc ccatggcgcc agaggaaacc aaaataacct cttttccctt
    49561 attcattaag cttgaaatca caaaggctaa atggtcgatc ttttctaagt taatcttccc
    49621 attagcaagc accagcgagc tggttccaat tttaattaca atacgcttta catcttcaaa
    49681 ttgtcgtttc atcatattag gattatagca taaaaaacag cccagaggac tgttagattg
    49741 aagccaaaat caatcagcct atcagcttga taaaaaaaag gatcactggc tacccattca
    49801 cctaagatat aaaaatccac ctgatagcca ctccaagcag gatttccttt gtgacaccac
    49861 ataccacgct acgctttatc ctattgtaag tttaagtctg atcctcctgc attgtcctgt
    49921 catttttaat gaccatatac caacactaaa gctattgaca aaaacgcaca atacgataaa
    49981 atgaaagcgc aaacagctat atttactacc taagggccag accttgctgt aaagcgcaat
    50041 acctgacaga aagaacacgt ttcagaagta gcaagaacaa gtcacaggca tactgtctgg
    50101 cacattggcg caaaggctac cagtgttcaa caagactgga acgcaaatca ataggctgga
    50161 aatcaagtag gaaaaccgta tcatttaaat ttttggaatc ccaagactca attgttctca
    50221 attagtttgg gggcttagga cgacagagcc tgtcagtcat ctaaagcaat taattagtta
    50281 taggaataaa tcactatggt taaactatca aaaagaagca agatagctat gtcattttta
    50341 attgtctttt gtggtatatt tttcgtcgct caaaaacgat tcggttcatc agaccaatca
    50401 tttaccgtaa ggccagacgc agatttctat atagtcggtt accacaatat tgaaggttat
    50461 caattgacaa atgagcagcc gcaaaaaatt tctgacgcta agctcgaagt ggtcaaaggt
    50521 cagatcaatc aagtggttaa acgagcagag ctttcaaatc gttatctggt cttttccgag
    50581 gaggggccac ctttgggggc aataggaaga cttatcgctc ttgattttca aaaaggcaac
    50641 gtgacgtatc acccaacagc tgattatgcc tttacttcct ccggagtatc accagattat
    50701 tatttcactt ctacagcaa
//
LOCUS       DARYYD010000009        48181 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.009, whole genome shotgun sequence.
ACCESSION   DARYYD010000009 DARYYD010000000
VERSION     DARYYD010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48181
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.009"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            121..255
                     /gene="rpmH"
                     /locus_tag="TV188_000440"
     CDS             121..255
                     /gene="rpmH"
                     /locus_tag="TV188_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEL1533829.1"
                     /translation="MKRTYQPSKIRRQRKHGFRHRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            542..1267
                     /locus_tag="TV188_000441"
                     /pseudo
     CDS             542..1267
                     /locus_tag="TV188_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678571.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
     gene            1286..2599
                     /locus_tag="TV188_000442"
     CDS             1286..2599
                     /locus_tag="TV188_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1533830.1"
                     /translation="MKMKKLASFVMLGASVLGLAACGSSSKEADKSDSAAKTEITWWA
                     FPTFTQEKADDSVGTYEKKIIAAFEKANPDIKVKLETIDFTSGPEKITTAIEAGTAPD
                     VLFDAPGRIIEYGKNGKLADLNDLFTDEFIKDVNNDNIIQASKAGDTAYMYPISSAPF
                     YMALNKKMLKDAGVLDLVKEGWTTDDFEKVLKALKDKGYNPGSFFANGQGGDQGPRAF
                     FANLYSSRITNDDVTKYTTDDANSVKSMEKIASWIKDGLLMNGSQYDGSADIQNFANG
                     QTSFTILWSPAQAGTQAKLLEASKVDYVEVPFPSEDGKPELEYLVNGFAVFNNKDDKK
                     IEASKKFIQFIADDKEWGPKNVVRTGAFPVRSSYGNLYDDERMAMVSKWTQYYSPYYN
                     TIDGFAEMRTLWFPMVQAVSNGDEKPAAALKAFTEKANKTIEKAQ"
     gene            2700..3587
                     /locus_tag="TV188_000443"
     CDS             2700..3587
                     /locus_tag="TV188_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003041053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1533831.1"
                     /translation="MNVNKLKMRETLVSYAFLAPVLVFFVVFVLVPMIMGFVTSFFNY
                     TMTDFTFVGLDNYVRMFQDPVFIKSLINTLIIVVGSVPIVVFFSLFVATKTYNKHVIS
                     RSFYRAVFFLPVVTGSVAVTVVWKWIYDPMSGILNYVLKYGHVIEQNISWLGDKHWAL
                     LAIIVILLTTSVGQPIILYIAAMGNIDNSLVEAARVDGATELQVFWKIKWPSLLPTTL
                     YITVITTINSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFKLSEYGYANTMGVFLAI
                     LISLISFAQFKFLGNDVEY"
     gene            3600..4430
                     /locus_tag="TV188_000444"
     CDS             3600..4430
                     /locus_tag="TV188_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1533832.1"
                     /translation="MRKKKLTASDILTTAILCLLTILFIFPFYWIMTGAFKSQPDTIV
                     VPPQWWPKAPTVENFKALIIQNPALKWLWNSIYISVATMLLVCGTSSLAGYALAKKRF
                     YGQRLLFSIFIAAMALPKQVVLVPLVRIVNFMGIHDTLAAVILPLVGWPFGVFLMKQF
                     SENIPTELLESAKIDGCGEIRTFFNVAFPIIKPGFAALAIFTFINTWNDYFMQLVMLT
                     SRDHLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGAVKG
                     "
     gene            4446..4901
                     /locus_tag="TV188_000445"
     CDS             4446..4901
                     /locus_tag="TV188_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEL1533833.1"
                     /translation="MLYDVLENIRRYKGIHRHLDVAIDFLLTRDLRSLTDGKHVILED
                     KVVLFIQHNCLNKEDNALFEYHKRYADLHLLVEGNERVRYGLGYKQEAVSFDEASDIG
                     FVTCERTYDLDLGNDCFCYFFPNEAHQPNGFNDDGDAVTKCLIKVLMED"
     gene            4926..5576
                     /locus_tag="TV188_000446"
     CDS             4926..5576
                     /locus_tag="TV188_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEL1533834.1"
                     /translation="MSSKKRKLMQSIFSLDSKWLRASATIFDLIVLNLLFVLSCLPVV
                     TIGIAKMALYASLRDYRQGDIGSVVGVYGSYLRRFAKRGLQLGILEVLLTSFILVDLY
                     LIQAQVSLFFQLFKISCIAILFVAIMVFLYAYPLAMRYDLPLMSLFQRSFILLSLFFP
                     FSFAFLAVMLLVVFLLQLSPLSLLGGLSLLAIIGISSLTYPYVVIMENLLQKVQLY"
     gene            5605..6525
                     /locus_tag="TV188_000447"
     CDS             5605..6525
                     /locus_tag="TV188_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEL1533835.1"
                     /translation="MKTLTKYQGIIPAFYACYDAEGNISPERVRALTQYYIDKGVQGL
                     YVNGSSGECIYQSVADRKLVLEHVMAVAKGKLTIINHVACNNTKDSIELAQHAEALGV
                     DAIAAIPPIYFRLPEHAVAAYWNAISAAAPNTDFVIYNIPQLAGIALTPSLYQEMLKN
                     ERVIGVKNSSMPVQDIQTFCAIGGDDHLVFNGPDEQFLGGRLMGASAGIGGTYGAMPE
                     LFLRLNQLIKDKDLETAKALQYAINDIIGLLVSAHGNMYGVIKEVLRINERLDIGSVR
                     SPLPELTENDLVICQQAAALIKQTKEQFCS"
     gene            6540..7424
                     /locus_tag="TV188_000448"
     CDS             6540..7424
                     /locus_tag="TV188_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1533836.1"
                     /translation="MKRYLAIDIGGTAIKYGLMTETADILEKHEIATEAHKGGPAILD
                     KVKDLVATYQEAGLAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKRVIEETFGIP
                     CDVENDVNCAGLAEAISGSAKDCPVALCLTIGTGIGGCLLIDSQVFHGSSYSACEVGY
                     IHLPDGAFQDLASTTALVRDVARRHGDAVSDWNGRRIFEEAKAGNHHCIAAIDQLVDY
                     LAQGLANICYVANPNAIVLGGGIMAQKDYLQDKILAALNNYLVPSIAEKTQLRFASHE
                     NNAGMIGAYYHFKHKEQV"
     gene            7424..7696
                     /locus_tag="TV188_000449"
                     /pseudo
     CDS             7424..7696
                     /locus_tag="TV188_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514912.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
     gene            complement(7738..8562)
                     /locus_tag="TV188_000450"
     CDS             complement(7738..8562)
                     /locus_tag="TV188_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEL1533837.1"
                     /translation="MIHNHRLISKMEAALDSMTSLEKSIAQFFMETDLKVEELTASDM
                     IKRLHVSQAALTRFAKKCGFTGYREFIFECQKSREAMDQKAPNLQNYNTKKVLMNYRE
                     LIEKATELINEKQLQDIAQWIENAERIYFYGKGSSALAAKEFKLRLMRLGVICEALDD
                     TDSFTWVNSSITDKCLVIGFSLSAQTASVLEALQTAGTRGAKTVLLTTQTDEIPYQLD
                     EIVHIATARHLNYGNRISPQFPMLFVTDIIYAYFLEINKEGKTKIFQETIINPSDK"
     gene            8791..9564
                     /locus_tag="TV188_000451"
     CDS             8791..9564
                     /locus_tag="TV188_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEL1533838.1"
                     /translation="MIEIFDTHTHLNVDHFSGKEEEELALAKEFGVSYHNVVGFDQET
                     IDQALTLADAYREVYATIGWHPTEAGSYTQAVEDSLIACLKHPKVVALGEIGLDYYWM
                     EDPKEVQIEVFKRQLQLAKDHDLPFVVHTRDALEDTYQVLKEAGVGPRGGIMHSYSGS
                     LEMAQRFVDLGMLISFSGVVTFKKAVDVQEAARHLPLDKLLVETDAPYLAPVPKRGRE
                     NHTAYTRYVVEKIAELRGLSVEEIAAATTANAKRVFRID"
     gene            9536..10132
                     /gene="rnmV"
                     /locus_tag="TV188_000452"
     CDS             9536..10132
                     /gene="rnmV"
                     /locus_tag="TV188_000452"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEL1533839.1"
                     /translation="MQRGCLELTEKLKIQEVIVVEGKDDTANLQRFYDVDTYETKGSA
                     ITDEDLERIDRLNKLRGVIVFTDPDYHGERIRKLIMRAVPTARHAFLRRHEAKPRSKS
                     KGRSLGVEHASFEDLQKALSQVTQSFDDESYFDISQTDLIRLGLLLAADSRKRREYLG
                     EVLRIGYSNGKQLLKRLKLFGITLSEVEDVMTSYQTEQ"
     gene            10476..11348
                     /gene="rsmA"
                     /locus_tag="TV188_000453"
     CDS             10476..11348
                     /gene="rsmA"
                     /locus_tag="TV188_000453"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEL1533840.1"
                     /translation="MRIADYSVTKSILDRYGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DKSVNVIEIGPGIGALTEFLAERAAEVMAFEIDERLVPILADTLRDFDNVQVVNQDIL
                     KADLQTQLKQFSNPDLPIKVVANLPYYITTPILMHLIESKIPFQEFVVMMQREVADRI
                     SAEPNTKAYGSLSIAVQYYMTAKIAFVVPRTVFVPAPNVDSAILKMTRRDQPLIEVQD
                     EDFFFRVSRVGFVHRRKTLWNNLVSHFGKAEDTKARLEQGLALAGIKPSIRGEALSIQ
                     DFGRLADALKQVGF"
     gene            11509..12381
                     /gene="rsgA"
                     /locus_tag="TV188_000454"
     CDS             11509..12381
                     /gene="rsgA"
                     /locus_tag="TV188_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEL1533841.1"
                     /translation="MQGKIIKALAGFYYVESEGQVYQTRARGNFRKRGQTPYVGDLVE
                     FSAEDNSEGYILAIAERKNSLVRPPIVNIDQAAVIMSAKEPDFNTNLLDRFLILLEHK
                     AIHPIIYISKIDLLEQPESIEAIGQHYRAIGYDFVTSLSHLLPLLAGKTTVFMGQTGV
                     GKSTLLNRIAPELALETGDISDSLGRGRHTTRAVSFYDAYNGKIADTPGFSSLDYGID
                     NAEDLNEAFPELRRLSHSCKFRSCTHTHEPKCAVKEALGNGELWSVRYQNYLQFLSEI
                     ENRRETYQKVSKRK"
     gene            12390..13052
                     /locus_tag="TV188_000455"
     CDS             12390..13052
                     /locus_tag="TV188_000455"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEL1533842.1"
                     /translation="MSSLKIAPSILAADYACFAAELARIEKTDAEYVHIDIMDGQFVP
                     NISFGADVVASMRKHSKLVFDCHLMVVNPERYVEAFAQAGADIMTIHVESTLHSHGAL
                     QKIRAAGMKAGVVINPGTPVSAVEPLLSLVDQVLIMTVNPGFGGQAFIPECLEKVAAI
                     AKMRDERGLSFDIEVDGGVDDKTIRACYQAGANVFVAGSYLFKAADLAAQVQTLRAAL
                     NG"
     gene            13045..13677
                     /locus_tag="TV188_000456"
     CDS             13045..13677
                     /locus_tag="TV188_000456"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEL1533843.1"
                     /translation="MVKVALFAGGDLSYFTCDFDYFVGIDRGSLFLLENGLPLNMAVG
                     DFDSIPQVAFEVVKEQAELLVQASPEKNDTDTELALKEVFTRFPEAEVTIFGAFGGRL
                     DHLLSNVFLPADPELAPFMAQICLRDQQNAISYRSSGWQTIRQDKDMTYVAFMADGDA
                     DLTITGAKFDLTTSNFFKKKVYASNEFIDQPIKVHVPKGYLIIIQSKDRS"
     gene            13679..14950
                     /locus_tag="TV188_000457"
     CDS             13679..14950
                     /locus_tag="TV188_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEL1533844.1"
                     /translation="MDLILFVLVLVLIGLAAYSFVSIKHLQSRLEKALDDNADNLSDQ
                     LTYQLDMANKSQLLELSTVMNRQQNELFQQLMVIRDTLHQGLAENRDRSDQRLETMTQ
                     SLSQAVKNLQDSNEKRLEEMRHTVEEKLEKTLKNRLQTSFEAVSKQLESVNQGLGEMR
                     TVAKDVGTLNKVLSNTKTRGILGELQLGQIVEDIMTANQYEREFATVSGSSDRVEYAI
                     KLPGNGQGDYIYLPIDSKFPLEDYYRLEDAYEAGDRAAIETSRKALLAAIKRFAKSIH
                     SKYLNPPETTNFGIMFLPTEGLYSEVVRNPAFFDSLRREENIVVAGPSTLSALLNSLS
                     VGFKTLNLQKNADDISKILGNVKLEFEKFGGLLAKAQKQLNTANHTLDQLMSTRTKAI
                     VRALATVEGYQDQSTQSLLHIPLLEEADDED"
     gene            14940..15878
                     /locus_tag="TV188_000458"
     CDS             14940..15878
                     /locus_tag="TV188_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEL1533845.1"
                     /translation="MKINQMKKDQPFEGFYLIKSAEVRKTRAGKDFIAFTFQDDTGEI
                     SGNLWDAQPYNVEEFVAGKIVFMKGRREVYNGTPQVNQITLRNIRPGEPNDPKEFKEK
                     APVSVTEVRDYLDQMLFKIENATWQRIVRALYRKYDKEFFTYPAAKTNHHAFESGLAY
                     HTATMVRLADSIGDIYPELNKSLLFAGIMLHDLAKVLELTGPDNTEYTIRGNLIGHIA
                     LINEEITKTITELNIDDNKEEVTVLRHVILSHHGQLEYGSPVRPRIMEAEIIHMIDNI
                     DANMMMMSTALSRIGEGEMTNRIFAMDNRSFYKPKY"
     gene            15978..16793
                     /gene="purR"
                     /locus_tag="TV188_000459"
     CDS             15978..16793
                     /gene="purR"
                     /locus_tag="TV188_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEL1533846.1"
                     /translation="MKLRRSERMVVISNYLINNPYKLTSLNTFATKYEAAKSSISEDI
                     AIIKKAFEESNIGEIDTLTGASGGVIFTPSISEAEARSIVEELCQRLSESNRILPGGY
                     IYLSDLLSTPKLLQNIGRIIANAFKGQKIDAVMTVATKGVPLANAVANILNVPFVIVR
                     RDLKITEGSTVSVNYASASSYRIEKMFLSKRSLKPNSRVLIVDDFLKGGGTITGMMSL
                     LTEFDSTLVGVAVFAENAQSEREQMSFKSLLKVSEIDVKNNRVVVEVGNIFDK"
     gene            16830..19334
                     /locus_tag="TV188_000460"
     CDS             16830..19334
                     /locus_tag="TV188_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC10/PgrA surface exclusion domain-containing
                     protein"
                     /protein_id="HEL1533847.1"
                     /translation="MEQENSRTKHVKSTIALTSTIALLGTSVGVSHQVKADDAKSGDA
                     NTSNTSEATLAKPETLEEAVLAVKATEETLSERKKELAETNTNIAETEGEIANLEATK
                     KEQIAELAKAEELLETYSSMSEEDLAKSIEKHETELETINTELEKATTESQAQAEAVA
                     KQQETIAAEATKADQLATQLTAAEQKVSDLNTMISQPEAIVSEAQAAKEEVKRISDDL
                     AKATANLATVKETVHSQLTSDLAANKAALAAKEAELQRLQNGVATAQLNVAGSNKLIL
                     PKDYPIEEIKKLAASGYIGTAAYNQYYQAVKDTMIAKAEPGAAMNQYVDIPEDLNRVV
                     DPDNLSQEVQNELAQFAAQMINDVRKQLGLVPVTVTVGSQEFARLLTKSYKETHQNTR
                     PSFVYGQVDASGHRGVGPHDQTIIEESAVKVGLRQKDDNMYENLGAFNEVHTVNGIKR
                     GIYDSIKYMLFTDHLHGNTYGHAVNFLRVDKTDPNAPVYLGFSTSNVESLNEHFVIFP
                     ESDIVDATRFSTTEIPKSGQVIDRSASIQALTNDIASIKGKIASLESRLADPSSEAEV
                     TAAQAKISQLQHQLEAAQAKSHKLDQQVEQLANTKDSLRTQLLAAKEEQAQLKANLDK
                     ALALLASSKATLHKLEAAMEEAKARVAGLASQKAQLEDLLAFEKNPNRIELAQEKVAA
                     AKKALADTEDKLLAAQASLSDLQAQRARLQLSIATIEQQLVLLKNLVQEKQRLRLEAE
                     RLNSMSETRQLLNQLAPQAAKAGVGSELVATGLLVSKVASAIAKQSPTSHSYGAGAAS
                     HAAVDDNTQRAVQAGMVMLAAAGLATVKLKKGSKKR"
     gene            19517..19930
                     /gene="rpsL"
                     /locus_tag="TV188_000461"
     CDS             19517..19930
                     /gene="rpsL"
                     /locus_tag="TV188_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEL1533848.1"
                     /translation="MPTINQLVRKPRKSKIEKSDSPALNIGYNSHKKVHTKLAAPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLIRGGRVKD
                     LPGVRYHIVRGALDTAGVADRKQGRSKYGAKRPKG"
     gene            19951..20421
                     /gene="rpsG"
                     /locus_tag="TV188_000462"
     CDS             19951..20421
                     /gene="rpsG"
                     /locus_tag="TV188_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEL1533849.1"
                     /translation="MSRKNRAPKREVLPDPLYNSKLVTRLINRIMLDGKRGTASSIVY
                     DAFSEIKEATGNDALEVFETAMDNIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTASRARGEHTMKDRLAKEIMDAANNTGASVKKREDTHKMAEANRAFAHFRW"
     gene            20964..23042
                     /gene="fusA"
                     /locus_tag="TV188_000463"
     CDS             20964..23042
                     /gene="fusA"
                     /locus_tag="TV188_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEL1533850.1"
                     /translation="MAREFSLAKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWDGHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVQTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPEEYLEQAQEYREKLIEAV
                     AETDEDLMMKYLEGEEITNEELVAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIA
                     YLPSPLDIPAIKGVNPDTDAEEERPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     NSGSYVMNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESIEVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIA
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLIESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKTAQPAILEPMMLVTITAPEDNLGDVMGHVTA
                     RRGRVDGMEAHGTSQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGE"
     gene            23059..23277
                     /locus_tag="TV188_000464"
     CDS             23059..23277
                     /locus_tag="TV188_000464"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533851.1"
                     /translation="MDSIPAFLMCYNRWAVQQLIKAMTEKSSPIRHKRLGKGLKKALL
                     TTLSDTFGCPKKLFAVSILMEKQSFENG"
     gene            23423..24433
                     /gene="gap"
                     /locus_tag="TV188_000465"
     CDS             23423..24433
                     /gene="gap"
                     /locus_tag="TV188_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEL1533852.1"
                     /translation="MVVKVGINGFGRIGRLAFRLIQNVEGVEVTRINDLTDPAMLAYL
                     LKYDSTQGRFDGDVEVVEGGFNVNGKFVKVSAEANPENIDWASQEVDIVLEATGFFAS
                     KAGAEKHLHANGAKKVVITAPGGNDVKTVVFNTNHEILDGTETVISGASCTTNCLAPM
                     AKVLQDKFGVVEGLMTTIHGYTGDQMTLDAPHRKGDFRRARAAAVNIVPNSTGAAKAI
                     GLVIPELNGKLDGAAQRVPVPTGSVTELVSVLEKDVTADEVNAAMKAAANDSFGYTED
                     QIVSSDVVGIHYGSLFDATQTKVLTVDGKQLVKTVSWYDNEMSYTAQLVRTLEYFAKI
                     AK"
     gene            24977..25831
                     /locus_tag="TV188_000466"
     CDS             24977..25831
                     /locus_tag="TV188_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HEL1533853.1"
                     /translation="MTSKKILNLVSLGLSLVLISGCTTNGEKKAAPSQDKDKQEKVVR
                     LTNDQLRARENTMATLWYQQSEEAKALYLQGYQVAKQRLDTLLSQATDKPYSIVLDID
                     ETVLDNSPYQAKNIKEGTGFTPDSWDKWVQKKSAKAVAGAKDFLQYANDKGVQIYYVS
                     DRTTKQVEPTMENLEKEGIPVQGKDHFLFLEEGVKSKEGRRQKVQETTNLVLLFGDNL
                     LDFAEFSKTSHEDRRKLLDQLHAEFGSKFIIFPNPMYGSWESSVYNGQKLDSEGQIKA
                     RDKALEAY"
     gene            26041..27237
                     /locus_tag="TV188_000467"
     CDS             26041..27237
                     /locus_tag="TV188_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEL1533854.1"
                     /translation="MAKLTVKDLDLKGKKVLVRVDFNVPLKNGVITNDNRISAALPTI
                     KYIIEHGGRAILFSHLGRVKEEADKEGKSLAPVAKNLAEKLGQEVIFPGSTRGAELEA
                     AIDALEDGQVLLVENTRFEDIDGKKESKNDPELGKYWASLGEGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIKEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYEAQGIEIGNSLCEEDKLDVAKSLLEKSNGKLVLPVDSKEANAF
                     ADYTEVKVTEGEAVDTGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQEG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKELPGL
                     AALTEK"
     gene            27660..28181
                     /locus_tag="TV188_000468"
     CDS             27660..28181
                     /locus_tag="TV188_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1533855.1"
                     /translation="MNYHFDASKLKLGMRTFKTGLAVFFVLLLFHFFDFQGLQIGALT
                     AVFSLRESFDKTISFGTSRILGNSIGGFFAIIFYLLDTLFQGAFWVTLVFVPILTMLT
                     IMFNVAFNNQSGIIGAVAALLIITLSIPTGEAFMYVIARVFETFCGVFIAILVNTDVE
                     LIRNKWLSRKLKK"
     gene            28257..28628
                     /locus_tag="TV188_000469"
     CDS             28257..28628
                     /locus_tag="TV188_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1533856.1"
                     /translation="MKEKELRRSMAVFPIGAVMTLTDLSARQIRYYEDQELIKPERTE
                     GNRRLFSLNDMDRLLEIKDFLDEGLNIAAIKREYAERQDKLMQKQKVLTDADVRRILH
                     DELLNQGGFSTPSQHIGNFRI"
     gene            28665..30011
                     /gene="glnA"
                     /locus_tag="TV188_000470"
     CDS             28665..30011
                     /gene="glnA"
                     /locus_tag="TV188_000470"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEL1533857.1"
                     /translation="MAITAADVRREVKEKHVTFLRLMFTDIMGVMKNVEIPATEEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWIVFPWGDENGTVGGLICDIYTAEG
                     KPFAGDPRGNLKRALKHMDEVGYQSFNLGPEPEFFLFKIDEAGEPTLEVNDKGGYFDL
                     APIDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYADALKACDNIQIFKLV
                     VKTIAREHGLYATFMAKPKFGIAGSGMHCNMSLFDKGGNNAFYDENDKRGMKLSDDAY
                     YFLGGLMKHAYNYTAITNPTVNSYKRLVPGYEAPVYVAWAGSNRSPLIRVPASRGMGT
                     RLELRSVDPTANPYLALAVLLEAGLDGIINKIEAPAPIEANIYMMTAEERNAAGIVDL
                     PSTLHNALKALQKDEVIQKALGDHIYTNFLEAKRIEWSSYATFVSQWEIDNYLHNY"
     gene            30244..31902
                     /locus_tag="TV188_000471"
     CDS             30244..31902
                     /locus_tag="TV188_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1533858.1"
                     /translation="MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINW
                     YTPTEIITLDISKNTDTYSALAIGNSGSNLLRADAKGKLQPDLAEKVDVSEDGLTYTA
                     TLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYLATESHLKNAEDINSGKNPDL
                     DSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTTSEKQIYSG
                     PYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANI
                     SGTSAIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVS
                     AAVDTGSKPATALVPTGLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDAL
                     TITITADADAPAAKSAVDYIKETWETALPGLTVEEKFVPFKQRLEDTKNQNFEVAVVL
                     WGGDYPKGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALTTDALNTDAAADDYKAAEK
                     ALYDNALYNPLYFRSGEGLQNPSIKGLIRNSTGLNVDFTYAYKD"
     gene            32071..32985
                     /locus_tag="TV188_000472"
     CDS             32071..32985
                     /locus_tag="TV188_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533859.1"
                     /translation="MIKYLLKRVAILVVTLWVVITLSFFLMQVMPGTPYNSPKLTDDM
                     IAMLNQQYGLDKPLWQQYLKYLFDILHGDFGTSYQSINQSVTTLISQRLGVSVHLGVQ
                     ALIVGISSGLAVGAVSARNKNNSIDAILSVISTLGISMPSFIIGLLLLDYLGFKWNLL
                     PLSGWGSFGQTILPTLALAIPVFAQVTRFFRSEMIETLSTDYIQLARAKGLTKRQVTR
                     RHAYRNSMIPVLTLVGPMAAGILTGSALIEQIFSIPGIGQQFVTSIPTKDYPVIMGTT
                     IVYALMLMVAILATDMIISIADPRVRLG"
     gene            32995..34026
                     /locus_tag="TV188_000473"
     CDS             32995..34026
                     /locus_tag="TV188_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1533860.1"
                     /translation="MLEETKSFKLVGAGSLATQEKIEKPALSFLQDAWRRLKHNKLAV
                     IAMGFLAVLLLFSIGSLFVVSTDDANSFNSKEVSIYRNLPPKLSSSLPFWNGTITYAG
                     NTEPNDAYADQGVPEDKAFLLGTDNLGRSIGKRITVGIRISLLIAIVATLIDLVIGVT
                     YGLVSGFVGGKTDMVMQRIIEIISSIPNLVIVTMLGLLLGNGVTSIIISIAIVGWTSM
                     ARQVRNLTLSYRERDFVLASRALGESNIRIAFKHVLPNISGIIIVQIMMTVPSAIMYE
                     SVLSAINLGVKPPTASIGSLITDAQESLQYYPYQVLLPAFALVLISLAFILLGDGLRD
                     AFDPKSSDE"
     gene            34038..35084
                     /locus_tag="TV188_000474"
     CDS             34038..35084
                     /locus_tag="TV188_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1533861.1"
                     /translation="MTNETILSVKNLHVDFKTYAGDVKAIRDISFELKKGETLAIVGE
                     SGSGKSVTTRTLMGLNAKNASISGNICFKGKQLNELKEEEWVKVRGNEIAMIFQDPMT
                     SLDPTMTIGMQIAEAIMIHQSIHKTEALKRALDLMRQVGIPNAEEHLKDYPHQWSGGM
                     RQRAVIAIALAANPDILIADEPTTALDVTIQAQILKLMKDIQSQTASSIIFITHDLGV
                     VAGMVDRVAVMYAGKIVEYGTVDEVFYHPQHPYTWGLLNSMPTTATAAGSLRSIPGTP
                     PDLLNPPKGDAFAARNEFALDIDHIKEPPMFKVSDSHYAATWLLDERAPKITPPFPIR
                     KRWAKWQEMEERKA"
     gene            35084..36019
                     /locus_tag="TV188_000475"
     CDS             35084..36019
                     /locus_tag="TV188_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1533862.1"
                     /translation="MTEARKKLIEVKNVSLTFNKGKKNEVKAIDRLSFDIYEGEVFGL
                     VGESGSGKTTVGRAILKLYDISDGEIIFNGENVSQLKGKKLHSFRKHAQMIFQDPQAS
                     LNGRMKIRDIVAEGLDIHGLTASKAEREARVQELLKLVGLNQNHLTRYPHEFSGGQRQ
                     RIGIARALAVKPTFIIADEPISALDVSIQAQVVSLMQQLQKKRGLTYLFIAHDLSMVK
                     YISDRIGVMHWGKMLEIGTSDEVYNHPIHPYTKSLISAIPEPDPEKERKRIAEVYDPS
                     QELDGQERQMHEITPGHFVLATQAEAEQYRAECGL"
     gene            complement(36648..38330)
                     /locus_tag="TV188_000476"
     CDS             complement(36648..38330)
                     /locus_tag="TV188_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEL1533863.1"
                     /translation="MTNISLRPNEVGVYAIGGLGEIGKNTYGIEYQDEIIIVDAGIKF
                     PEDDLLGIDYVIPDYSYIVDNLERVKALVITHGHEDHIGGIPFLLKQANVPIYAGPLA
                     LALIRGKLEEHGLLRDAVLYEINHNTELTFKHMSVTFFKTTHSIPEPLGIVIHTPQGK
                     VICTGDFKFDFTPVGDPADLHRMAALGKDGVLCLLSDSTNAEIPTFTNSEKVVGQSIM
                     NIIEGIHGRIIFASFASNIYRLQQAAEAAVKTGRKIAVFGRSMEKAIVNGIELGYIKV
                     PKGTFIEPNEIKHYHASEILIMCTGSQGESMAALARIANGTHRQVSLQPGDTVIFSSS
                     PIPGNTVSVNKLINTIQEAGVDVIHGKVNNIHTSGHGGQQEQKLMLSLIKPKYFMPVH
                     GEYRMQKVHAGLAVDIGIPEENIFIMENGDVLALTSDSARIAGHFNAQDIYVDGNGIG
                     DIGTAVLRDRRDLSEDGVVLAVATVDFETQMILAGPDILSRGFIYMRESGELIRESQR
                     VLFNAIRIALKNKDASIQSVNGAIVNALRPFLYEKTEREPIIIPMVLTPDSQ"
     gene            complement(38332..38562)
                     /locus_tag="TV188_000477"
     CDS             complement(38332..38562)
                     /locus_tag="TV188_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEL1533864.1"
                     /translation="MIYKVFYQETKERSPRRENTQALYLDIDAASELEGRIKARKMVE
                     EHTDYNVEFIELLSDKHLDYEKETGVFTLTEF"
     gene            38848..39546
                     /gene="tsaB"
                     /locus_tag="TV188_000478"
     CDS             38848..39546
                     /gene="tsaB"
                     /locus_tag="TV188_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEL1533865.1"
                     /translation="MKTLAFDTSNKALSVALLDDGTLLADLTINVKKNHSISLMPAID
                     FLMSSADLKPKDLDRIVVAEGPGSYTGLRVATATAKMLAYSLSIDLVGVSSLYALAAS
                     TCRENPDSLVVPLIDARRRHVYVGYYHHQKAVKQDKYASFDAVLAELVSCDHVIFVGE
                     VEGFAEDIRSALPEAKIKPSLPSAFEVGLLGSSLSADNVAAFVPQYLKRVEAEENWLK
                     THAAGDDSQYVKRV"
     gene            39549..39974
                     /gene="rimI"
                     /locus_tag="TV188_000479"
     CDS             39549..39974
                     /gene="rimI"
                     /locus_tag="TV188_000479"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEL1533866.1"
                     /translation="MMSIQEKAAAVYQVLKEVYGQSPWTLKQIVSDMQQEHVDYFTFY
                     HQETLLGFLAIQQLPGEMEITNLAVLPSYQGQGIASWLMGQLDGFEGVIFLEVRASNH
                     RAQQLYLKHGFEVVGQRSNYYHDPIEAALIMRREGKNDR"
     gene            39964..40980
                     /gene="tsaD"
                     /locus_tag="TV188_000480"
     CDS             39964..40980
                     /gene="tsaD"
                     /locus_tag="TV188_000480"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEL1533867.1"
                     /translation="MTDRYILAVESSCDETSVAILKNDNVLLTNIIASQVESHKRFGG
                     VVPEVASRHHVEVITTCFDDALKEAQLEASDLTAVAVTYGPGLVGALLVGLAAAKAFA
                     WANDLPLIPVNHMAGHLMAAREQGELEYPLMALLVSGGHTELVYVTEPGEYHIVGETR
                     DDAVGEAYDKVGRVMGLPYPAGREIDQLAHQGTDTYHFPRAMMKEDHLEFSFSGLKSA
                     FINLHHNAQQKGEELVLEDLCASFQAAVLDILLAKTKKALKQYPSKMLVVAGGVAANQ
                     GLRERLAEEITDIAVVIPPLRLCGDNAGMIALAAVVEYEKGHVAGLDLNAKPSLAFDS
                     FHQQ"
     gene            41002..42030
                     /locus_tag="TV188_000481"
     CDS             41002..42030
                     /locus_tag="TV188_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HEL1533868.1"
                     /translation="MFYLLLPPLICSVVFLAVYIKEPRTLWLGASFVTTLGVSLLCAM
                     IYIFSIEEKLQGVGILVLGVIGFLAIVWLMSSPFILLLFLSFNGIRLIKREGLSFRNL
                     LLIGSAVLLFVHPFISRLLLESIGDSKLLRIMYETSDLLILYLLLIVSVYTISSMLNT
                     FYFRKTKEDYIIVLGSGLNGDQVTPLLASRINKGIQIYQKNPGSKLIMSGGKGADELI
                     AEGEAMCRYAIQQGIKSEDILVENQSRNTRENILLSKQLIPSGASFCLVTNRYHLFRA
                     LLLAKELALPCRCYGAKTKLYFSMNAFIREIVGYLQLKKKQHLLAMLILTVGYIAIRV
                     VMIYMLHI"
     gene            complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TV188_000482"
     CDS             complement(42425..42694)
                     /gene="rpsN"
                     /locus_tag="TV188_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001085658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEL1533869.1"
                     /translation="MAKKSKIAKYHKQLQLIEQYADLRRELKAKGDYEALRKLPRDSN
                     PNRLKNRDRIDGRPHAYMRKFGVSRINFRELAHKGQLPGITKASW"
     gene            complement(42888..44060)
                     /locus_tag="TV188_000483"
     CDS             complement(42888..44060)
                     /locus_tag="TV188_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1533870.1"
                     /translation="MILYDTIIIGGGPAGMMAAISSSYYGYKTLLLDKNKRLGKKLAG
                     TGGGRCNVTNSGSHDELIAGIPGNGRFLYSVFSQFDNHDIIAFFKENGVTLKEEDHGR
                     MFPTTDQSKTIINALEQKIKSLGAQVLISTEIVSVKKRNNLFYLKSVDQTFSCERLIV
                     ATGGKSYPSTGSTGFGYDIARHFNIAVTELEAAESPLLTDFPHKALQGISLADVTLSC
                     GKHQITHDLLFTHFGLSGPAALRLSSFVKGGDIAELDLLPQTSAAELLSYLAQHREKA
                     LKNALKTLMPERVADFLAKGYPEKGKQLTPTQTQELVNRIKQLPIPITGKISLAKSFV
                     TKGGIDLKEINPKTLESKKVAGLYFAGEVLDVNAHTGGFNITAALCSGWVAGSSQS"
     gene            44186..44716
                     /locus_tag="TV188_000484"
     CDS             44186..44716
                     /locus_tag="TV188_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HEL1533871.1"
                     /translation="MAIEKTVSELADILGVSRQAVNNRVKSLPEEDLDKNDKGVTVVK
                     RSGLVKLEEIYKKTIFDDEPISEETKQRELLEILVDEKNTEITRLYEQLKAKDSQLAA
                     KDEQMRIKDVQIAEKDKQLDQQQQLTAKAMADKETLKLELEEAKAEADQVRLQAEEIQ
                     SEMGPKKGFLNRLFGK"
     gene            44761..45348
                     /locus_tag="TV188_000485"
     CDS             44761..45348
                     /locus_tag="TV188_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEL1533872.1"
                     /translation="MKQLEAYIAFDMEFNTVNEVSHIIQLSAVKWHKHQEVDSFDSYV
                     YTAVPLQSFINGLTGITSDKIVSAPKVDEVLDAFKQFVGDTPLIGYNAQKSDLPILAA
                     NGLDLSAQYAVDVFDEAYERRSSDLNGIANLRLQTVADFLGIKGRGHNSLEDARMTAR
                     VYEAFVEFDDNKSYLNKQKEAIADNPFAALGGLFD"
     gene            45452..46174
                     /locus_tag="TV188_000486"
     CDS             45452..46174
                     /locus_tag="TV188_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEL1533873.1"
                     /translation="MSDIYSTGELAKAAGVTVRTVQYYDKRGILLPSQLTEGGRRIYT
                     ESDLERLKIICFLRDLDFSIEQIKRVLAEDNVMAVLDLLLVDHIQQLEQDLRTKKHQL
                     DTAVKLLSGIRCSSSHSIKNLSDMSLTMNNQKAWRRLQLKMFSNIALAILVHVMLVLL
                     TSYFHLSWLVWIEAPLWIIFFTLLIVYFRKQFEYLCPNCHTIFEPDFKEFALAGHTPR
                     TRRLTCPHCHQKSYCLELAKEK"
     gene            complement(46216..46515)
                     /locus_tag="TV188_000487"
     CDS             complement(46216..46515)
                     /locus_tag="TV188_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016503193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEL1533874.1"
                     /translation="MMNMQNMMKQAQKLQKQMEQKQADLAAMQFTGKSAQELVTATFT
                     GDKQLVSIDFKEAVVDPEDIETLQDMTAQAINAALAQIDEATKKTLGAFAGKLPF"
     gene            46913..47500
                     /locus_tag="TV188_000488"
     CDS             46913..47500
                     /locus_tag="TV188_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533875.1"
                     /translation="MTTTKQSKTTLAARYLKLGLTSAMFAGGAFLALGSAPAVSASTH
                     AGNDQPATQRLTDQEIYERAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAP
                     QPPAAPQLTDQDAQKLDLPDYVRGSIYGILNQNSSVTYPKDIAGLEQSEAPQPPAAPQ
                     LTDQDAQQLDLPDYVRGSIYGILNQNSSITYPRDY"
     gene            47639..>48181
                     /locus_tag="TV188_000489"
     CDS             47639..>48181
                     /locus_tag="TV188_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1533876.1"
                     /translation="MTYKILLVDDELEIIDINERYLQQAGYRVTTASDGSQALELFHK
                     DQYDLIISDVMMPNMDGYDFIGEVLLEKPDQPFLFITAKTSEPDKIYSLSLGADDFIS
                     KPFSPRELVLRVKNILNRIYGKANQADSLVIGDLVMDHSTRRVTVANQDLNLTNKAFD
                     LLWILANHLNHVFSKTELYER"
BASE COUNT        13643 a         9419 c        11267 g        13852 t
ORIGIN      
        1 aaaggaaaat agagcttgac aggggagttt gattattata gaataatagg gtatgtttag
       61 taactgatat cacaaatagc cggctaaacg aatacgaaaa tctatgagga ggtattcact
      121 gtgaaacgta cttatcaacc aagtaagatc cgtcgtcagc gcaagcatgg cttccgtcac
      181 cgtatgtcaa ctaaaaacgg ccgtcgtgtg cttgctagcc gtcgtcgcaa aggacgcaaa
      241 gtattgtcag cataattgca gaatacatca attaaacaaa tcaggagtgc tcgaggctct
      301 tggtttttta attgttcaaa agtgctaaga gcagcttgat gagtgcttat aaagcaggag
      361 ataggagcca aaaagaggct gcttttttaa ttgctcttcc tgaatacgtt ttcaaaaata
      421 acggaaatag ggctaaaaat gaaagtagtt tctaaaacca gaggaagtat tgaaaacgct
      481 ttaatatctg ctacaataaa gatgtgaacg ttctctaaaa ttaataaaag gagtagaaag
      541 catgcttgaa aaaccaagca aggcagagct actggcagct ctgaaggacg ggctgatcgt
      601 ttcctgtcaa gctctgccgg gcgagcctct ctattcagag gcaggaggta tcatgcctct
      661 gatggtaaag gcagcagagg aagcaggagc agtagggata cgagccaatg gtgttcgaga
      721 tattaaggaa atccaagcgg tgacggatct gccaatcata gggatcatca aaaaggagta
      781 tcctccgcaa gcgcccttta tcacgccaac catggcagag gtagatgcct tagcggcctt
      841 aggtgtagcg gtgatagcct tggattgtac gcaaagggag cgtcatgatg gcttagcgat
      901 agtggatttt attcgagcga taagggagaa gtacccagag cagctgttta tggcagacat
      961 cagtacgctt gaatagggtc tagcagccta tgaggctggt atagattttg tagggacgac
     1021 cttatcaggg tatacgccct atagtcgtca ggggacaggt ccggatatgg agctgataag
     1081 tgccttgtgt gatgcagggg tatcagtgat agctgagggc aagattcata gtccagagga
     1141 ggccagggct gttcaggcct tgggagtagc tggtattgtg gttggtggtg ctattaccag
     1201 accaaaggaa attgcagagc gctttgtggc ggctttgaca tcgtcattgt ctataaaaaa
     1261 taattaatat aaaggagaat ttacaatgaa aatgaagaaa ttagcttcat ttgtgatgct
     1321 tggagcatct gttttagggt tagcagcctg tggcagtagc agcaaggagg ctgacaaatc
     1381 agattcagct gctaagacag agatcacctg gtgggccttt ccaaccttca ctcaagaaaa
     1441 ggctgatgat agcgtaggaa cctacgaaaa gaaaattatt gcagcctttg aaaaggccaa
     1501 tccagatatt aaggtcaagc tagaaaccat tgatttcacc tctggtccag aaaaaatcac
     1561 tactgcgatt gaggcaggta cagcaccaga tgtgctcttt gatgctccag gtcgtatcat
     1621 tgagtatggt aaaaacggta aattagctga cttaaatgac ctgtttactg atgagtttat
     1681 caaggacgtc aacaacgata acattatcca agcctctaaa gcaggagata cagcttatat
     1741 gtatcctatc agctcagcgc cgttttatat ggccttaaat aaaaaaatgc tcaaggacgc
     1801 tggtgttctt gaccttgtca aagagggctg gacaaccgat gattttgaaa aggtcttaaa
     1861 agccttaaag gataagggct acaatcctgg gtcattcttt gccaatggtc agggtggtga
     1921 ccaaggtcct cgtgccttct ttgccaacct ctatagcagc cgcatcacaa atgacgatgt
     1981 gactaagtac accactgatg atgctaattc tgtcaagagc atggagaaaa tcgcaagctg
     2041 gattaaggat ggccttctaa tgaatggctc tcaatatgat ggctcagctg atattcaaaa
     2101 ctttgctaat ggtcaaacct catttacaat cctatggtca ccagcgcaag caggaacaca
     2161 ggctaagctg ttggaagcaa gtaaggttga ttatgttgag gttccattcc catcagagga
     2221 cggcaagcct gaattagaat acctagtgaa cggctttgca gtgttcaaca acaaggacga
     2281 caaaaagatt gaagcttcta agaaatttat ccagtttatc gcagatgaca aagaatgggg
     2341 tccaaaaaat gtggttcgta caggtgcatt ccctgtaaga agctcttatg gtaatctcta
     2401 tgatgatgaa cgcatggcaa tggtttctaa gtggacacaa tactattcac catactacaa
     2461 cactattgat ggctttgctg agatgagaac actatggttc ccaatggttc aggcagtatc
     2521 aaatggagat gaaaagcctg cagcagccct caaagcattc actgaaaaag caaataaaac
     2581 catcgaaaaa gcacaatagt gtgagataaa agtggctcct tttcaatgca catgtccaat
     2641 ggtcactggt aaggagcctt tccttttagg aagattaata gaaaaagagg tatctttgag
     2701 tgaacgtcaa taagttaaaa atgagagaga cactcgtttc atatgctttt ttggccccgg
     2761 tcttggtttt ctttgtggta tttgttttag taccaatgat tatgggcttt gttactagct
     2821 tttttaatta tacgatgaca gactttacct ttgtcgggct tgataactat gtgagaatgt
     2881 ttcaggatcc tgtgtttata aagtctttga ttaataccct tattattgta gttggttcag
     2941 taccaattgt tgttttcttt tcattatttg tagcgacaaa aacctacaat aagcatgtga
     3001 tttcacgttc gttttaccgg gcggttttct tcctgccagt tgtgacaggt agtgttgcgg
     3061 taacagttgt ttggaaatgg atctatgatc ctatgtcagg tattttgaac tatgtgctaa
     3121 agtatgggca tgttattgag caaaatatta gctggcttgg ggacaagcat tgggccttgc
     3181 tggctattat tgtgatttta ttaacaacct ctgttgggca gcctattatt ctttatattg
     3241 ctgcgatggg aaatattgac aattccttag tggaggcagc tcgtgttgac ggtgcgactg
     3301 aattgcaggt cttttggaaa ataaaatggc caagtctatt gccaaccact ctctatatca
     3361 cggtcatcac aacgatcaat tctttccaat gctttgcctt gattcagctg ttgacctctg
     3421 gtggtccaaa ctattcaacc agcaccctga tgtactatct ttacgaaaaa gccttcaagc
     3481 tatcggaata cggctatgct aacacgatgg gggttttctt ggctatcttg atttcactga
     3541 tcagctttgc ccaattcaaa ttcttgggta atgatgtgga atattaaaag gagcttgaca
     3601 tgaggaaaaa gaaattaaca gcatcagata tcctaacaac agccattcta tgtttattaa
     3661 caatattatt tattttcccc ttttattgga tcatgacagg agcctttaaa tcccagccgg
     3721 atactattgt tgtcccacca caatggtggc caaaggcacc tactgttgaa aattttaagg
     3781 ccttgattat tcaaaatccg gctcttaaat ggctctggaa cagtatctat atttctgttg
     3841 ccaccatgct tttggtttgt ggcacctctt ccttggcagg ctatgcttta gcaaaaaaac
     3901 ggttttatgg gcaacgtttg ttgttttcaa tctttattgc tgctatggct ctgcctaagc
     3961 aggtcgtctt ggtgccattg gttcgtattg tgaattttat gggcatccac gatacgctag
     4021 cagcagttat tttgcctttg gtgggctggc cttttggggt attcctgatg aagcaatttt
     4081 cagaaaacat accaacagag ctgctggagt ctgccaaaat tgatggctgt ggtgagatta
     4141 gaaccttctt taacgttgct tttccaatca ttaagccagg ttttgctgcc ttagcgatct
     4201 ttacctttat taatacctgg aatgactact ttatgcagct agtaatgcta acatcaagag
     4261 atcatttgac aatatccttg ggggtagcca ctatgcaggc tgagatggca acaaactatg
     4321 gtttgatcat ggctggtgca gctcttgccg cagttccgat tgttacagtc tttcttgtgt
     4381 tccaaaaatc ctttacccaa ggtatcacca tgggagctgt caaaggttag aaaggtcagg
     4441 agattatgct ctatgatgtc ttggaaaaca ttcgtcgcta caagggtatc catcggcatt
     4501 tagatgtggc cattgacttt ttattgacaa gagatttaag gtcactcaca gatggcaagc
     4561 atgtgatttt agaggataag gtggttctct ttattcagca taattgtctc aataaagagg
     4621 ataatgcctt gtttgaatac cataagcgct atgccgattt gcatctacta gtcgagggga
     4681 atgagcgagt acgctatggc ttaggctaca agcaggaggc tgttagcttt gatgaggcat
     4741 cagacatcgg ctttgtgacc tgcgagagga cttatgactt ggacttggga aatgattgtt
     4801 tttgctattt ctttcccaat gaagctcatc agcctaatgg ctttaacgac gatggtgatg
     4861 cggtcacaaa atgcttgatt aaggtgttga tggaagatta actagaaagg atagggagta
     4921 atgatatgag cagcaaaaaa agaaagctaa tgcagtccat ttttagcttg gatagcaaat
     4981 ggctgagggc tagtgctact atctttgacc ttatcgtgct caatttgctt tttgtgctgt
     5041 cttgcttgcc tgtggtaacg attggcattg ccaaaatggc cttgtatgct agtctgcgag
     5101 attaccggca aggggatatc ggctctgttg taggcgtcta cggctcttat ctacggcggt
     5161 ttgccaagag aggccttcaa ttagggatcc tagaagtgct cttgacgagc tttatcttgg
     5221 ttgaccttta tctcattcag gctcaggtgt cgcttttctt tcaactattt aagattagct
     5281 gtatagcgat attatttgtg gctattatgg tctttttgta tgcttatcct ttagctatgc
     5341 gatatgattt gcctcttatg tcattatttc agcgaagctt tatcttgctt agtcttttct
     5401 tcccctttag ctttgctttt ttagctgtta tgctgctagt ggtctttttg ctgcagctat
     5461 ctccgctaag tctattagga gggctgtcgc ttttagccat tattggcatt agcagcctaa
     5521 cctatcctta tgtcgtcatt atggaaaacc ttcttcaaaa ggtacaactt tattaaaaat
     5581 aagatttaga aaaagagtgt cattatgaaa actttaacca aatatcaagg gattatccct
     5641 gccttttatg cctgctacga tgctgagggc aacatcagtc cagagcgtgt tcgtgctttg
     5701 acacaatatt atattgataa gggtgtccaa gggctttatg tcaatggctc atcaggcgag
     5761 tgcatttacc aaagcgttgc agaccgtaag ttggtcttag agcatgtgat ggcagtagcc
     5821 aagggcaagc taaccattat caatcacgtt gcctgcaaca ataccaagga cagcattgag
     5881 ctggctcagc atgctgaggc cttgggggtt gacgctattg cagcgattcc accgatttat
     5941 ttccgtttgc cagagcatgc tgtggctgct tactggaatg caatttcagc tgctgctcca
     6001 aatactgatt ttgtgattta caatattcct caattggctg gtattgcctt gaccccaagc
     6061 ctctatcagg aaatgctcaa aaatgagcgt gtcataggtg tcaaaaactc ctccatgcct
     6121 gttcaggata ttcaaacatt ttgtgctatc ggaggtgatg atcaccttgt ctttaatgga
     6181 ccggacgagc aatttttagg gggtcgtctc atgggggcct ccgctggaat tggcggtacc
     6241 tatggagcga tgccagagct tttcttacgc ttaaatcaat tgatcaagga caaggaccta
     6301 gagactgcta aggccttgca gtacgctatc aatgatatta ttgggttatt ggtttctgcc
     6361 catggcaata tgtatggtgt tatcaaggaa gtgctgcgca ttaatgagag gctggatatt
     6421 ggctctgttc gttctccttt gccagagtta accgaaaatg atttggtgat ctgtcagcag
     6481 gctgcagcct tgattaagca gaccaaggaa caattttgct cttaaaatga ggtgatcaaa
     6541 tgaagcgtta tcttgctatt gatattggcg gtacagccat caaatatggc cttatgacag
     6601 agacagcaga catactggaa aagcatgaaa tcgccactga ggctcataag ggcggtcctg
     6661 ctattttaga caaggtcaag gacctggttg cgacctatca ggaggctgga ctagctggtg
     6721 ttgcgatttc ttcagctggc atggtggatc ctgataaggg cgaaatcttt tacgcagggc
     6781 cacaaattcc gaactacgca ggcacgcagt ttaaaagggt gattgaagaa acctttggta
     6841 ttccctgtga tgttgaaaat gatgtcaatt gtgccggtct agcagaggct atttctggca
     6901 gtgctaagga ttgccctgta gccctttgct taaccatcgg tacaggaatt ggcggctgcc
     6961 tgctgattga ttcgcaggtt tttcatggca gcagctactc tgcctgtgag gtaggctata
     7021 tccatttgcc ggacggtgcg tttcaggatt tggcctccac aacagctctt gttagagatg
     7081 ttgctagacg tcatggagat gctgttagcg attggaatgg tcgtcgtatt tttgaagagg
     7141 ctaaggcagg taaccaccat tgtatagcag ccattgacca gttagttgac tatctagctc
     7201 aagggcttgc caatatctgc tatgttgcta atccaaatgc tattgtctta ggcggtggca
     7261 ttatggctca aaaggactat ttgcaggata aaatcctagc tgccctcaat aattatctgg
     7321 tacctagcat cgcagaaaaa acccagcttc gatttgccag ccatgaaaac aatgctggta
     7381 tgattggggc ttactaccat ttcaagcata aggagcaagt ctaatgatag aaaccatgtc
     7441 acttgaagag atgatgtcct acagggggcg tcacgaggtg cccaaggatt ttgatcattt
     7501 ttgggagacc tgtatcaagg aaaatcaagc tgcctcttat cagcttgatc aaaaggattt
     7561 tggccttgat tttgctgatt gctatgagtt gcgcttcaaa gggagtaatg gctcaacgat
     7621 ctatgccaaa tgtgtctttc caaaagccaa gcagctagtc ccagttgtct tttattttca
     7681 tggctaccag ggtcagtaca cagctagcta gggtcattga ggtgcttttt tgtgatgcta
     7741 tttatctgaa ggattgataa tcgtctcttg gaaaattttt gttttgcctt ccttgttgat
     7801 ttctaaaaaa taagcgtaga taatatccgt tacaaagagc attggaaatt gtggggagat
     7861 acgattgcca tagttaaggt gacgagcagt agcgatatgc acaatttcgt caagctggta
     7921 agggatttca tcggtctggg ttgtgagcag cactgtcttg gcaccgcgtg tcccagcggt
     7981 ctgcaaagcc tctaagacgg acgctgtttg agcagagagc gaaaaaccaa taaccaagca
     8041 tttgtctgta atgctgctgt taacccaggt gaagctatca gtgtcatcta aggcctcgca
     8101 aataacacca agtcgcatca gacggagctt gaattctttg gcggcaagag ctgagctgcc
     8161 cttaccgtaa aaataaatcc gctcagcatt ttcaatccat tgcgcaatgt cttgtagctg
     8221 cttttcattg atcagctcgg tagccttttc gatcaattca cggtagttca taaggacctt
     8281 tttagtgttg taattttgca ggttgggtgc cttttgatcc attgcctcgc gacttttttg
     8341 gcattcaaag ataaattcgc gataaccggt aaagccacat tttttggcaa agcgtgtcaa
     8401 ggctgcctgt gagacatgaa gccttttaat catgtctgaa gctgttagct cttcgacctt
     8461 taggtctgtt tccataaaaa attgagcgat gcttttttct aagctcgtca tgctgtctag
     8521 tgcagcttcc attttgctga ttaaacggtg attgtgtatc atatgaactc cctgatgtaa
     8581 ggctgtctat tataatagta tatcataaaa aggaaaaaga taaagaatac agataatata
     8641 ataatataga gctgatatta cagttatgtc aaggctgact gtttgagtaa accaagagct
     8701 atgctaagaa tgaagtagct gatgagatat ggtataataa tcaagcaggt atccctttta
     8761 gggcaataca agaaagagga atgactaaga atgatagaaa tttttgatac ccatacgcat
     8821 ttgaatgtgg atcattttag tggtaaagag gaagaggaat tagcacttgc taaggagttt
     8881 ggggttagct accataatgt cgttggcttt gatcaggaga ctattgatca agcccttacc
     8941 ttagctgatg cttataggga ggtctatgca acgattggct ggcacccgac tgaggctggc
     9001 tcttacacac aggcggttga agatagtctg attgcttgct tgaagcaccc aaaggttgtt
     9061 gccttaggag agattggctt ggattactat tggatggagg accccaagga ggtacagata
     9121 gaggtcttta agcggcagct acagcttgct aaggaccatg acctcccctt tgtggtgcat
     9181 acgcgtgatg cccttgagga tacctatcag gtcttaaagg aggctggagt gggtcctaga
     9241 ggtggtatca tgcattctta ctcaggatca cttgagatgg ctcaacgatt tgtagatctg
     9301 ggtatgctga tttccttttc aggggttgtc acctttaaaa aggcggttga tgttcaggaa
     9361 gcagcaagac acctgccgct ggataagctc ttggtggaaa cagatgcccc ctacctcgcc
     9421 ccagtaccaa agagaggacg tgaaaaccat accgcctata cgcgttatgt tgttgagaaa
     9481 atcgcggagc tacgtggttt atcagtagaa gagatagctg cagcaacgac tgccaatgca
     9541 aagagggtgt ttagaattga ctgagaagct taaaattcaa gaggttattg tggtagaggg
     9601 gaaggacgat accgctaatt tacagcgctt ctatgatgtc gatacctatg aaacaaaggg
     9661 ctctgccatc actgatgagg acttagaacg cattgatcgg cttaacaagc tgcgtggtgt
     9721 gattgtcttt acggatccag attatcatgg cgagaggatt cgcaaactga ttatgagagc
     9781 tgtcccaaca gctcgtcatg cctttttacg tcgacatgag gctaagccaa ggtccaaaag
     9841 taagggacgt tccttaggtg tggagcacgc tagctttgag gacctgcaaa aggctctgtc
     9901 tcaggttacc cagtcttttg atgacgagag ttattttgat attagtcaga cagatttgat
     9961 tcgtctaggg cttttattgg cagctgatag ccgcaagcgc agagagtatc taggagaagt
    10021 ccttcgtatc ggctattcca acggaaagca gctcctaaag cgcctaaagc tatttggcat
    10081 taccctatca gaggttgagg acgtgatgac ctcctatcag actgagcaat agatggcgct
    10141 agaaaggctg attggatcaa acaaaagagc cctgagactt cttgttctgg ctccaaaaaa
    10201 ttagataaga aatggtaaca aggattgaat tctgtattgg gcaggagtca gtccttttaa
    10261 ctttcttaga taagcattct ctgttctaag acgttcattc tccttgaagt tgctctagtt
    10321 ctccagatgt tctttgattg atgtcctctc ttgcttggtt tccctcttgt tttatcaaga
    10381 atagtataac cattttcatc tctttttttg ctgtggctct gataaataat agaaatatgc
    10441 tacaatagat ataaaacaat gaataggaca tcaacatgag aattgcagat tacagtgtaa
    10501 ccaagtctat ccttgatcgc tatggtttta cctttaaaaa atcatttggt caaaatttct
    10561 tgacggatac taatatttta cagaagattg ttgatacggc tgagattgac aagtcagtca
    10621 acgtcattga gattggtcct ggtatcgggg ctttgaccga atttttggca gaaagggctg
    10681 cagaggtcat ggcctttgag attgatgagc gcttggtgcc aatactggct gatacgcttc
    10741 gtgattttga caatgttcag gtggttaatc aggatatttt aaaggcagat ttacagaccc
    10801 agctaaagca atttagcaat ccggaccttc ctatcaaggt ggtagccaat ttgccctatt
    10861 acatcactac acccattttg atgcacctga ttgaaagtaa gattcccttc caagaatttg
    10921 tcgtcatgat gcagcgcgag gtggcagatc ggatttcagc tgagcccaat accaaggcct
    10981 atggctcttt gtctatagca gtccagtatt atatgaccgc taagatagcc tttgttgttc
    11041 ctaggactgt ttttgtgcca gcaccaaatg tggattcggc aattctgaag atgactcgtc
    11101 gtgaccagcc cttgattgag gttcaagatg aggatttctt ttttagggtg tcacgagtag
    11161 gctttgtgca tcgcagaaag acgctttgga ataacttggt tagccatttt ggcaaggctg
    11221 aggacacaaa ggcaaggctt gagcagggac tagctctagc tggaatcaag ccttctatcc
    11281 gaggagaagc gctgtctatt caagattttg gacggttagc tgatgcccta aagcaagtag
    11341 gcttctagtg ccttagttat gattgtagct tgtcacagca atcctgctgt ggctttttta
    11401 gatagtggtg ggttcatctt atctttggtg aaacttgggc taaactgctg aattcgaatg
    11461 atttttctga tataatggca ttattctagg ataaaaaaag gagttcattt gcaaggcaaa
    11521 atcattaagg ctctggctgg cttttactat gttgagtcag aggggcaggt ttatcaaacg
    11581 cgggcgcgtg gcaattttag aaagcgtggt caaacaccct atgtaggaga tttagtagaa
    11641 ttttctgctg aggacaattc agagggctat attttagcta ttgctgagcg gaaaaatagt
    11701 ctggtgcgtc ctcccattgt caatattgat caagcagctg tcattatgtc agccaaggag
    11761 cctgatttta ataccaacct tttagatcgc tttctcattt tacttgagca caaggccatc
    11821 caccctatta tttacatttc aaaaatagac ctgcttgagc agccagagag tatcgaagcc
    11881 attggtcagc attatcgtgc gattggctat gattttgtga cgagcttatc acatctgctg
    11941 ccattattag ctggtaagac aacagtattt atggggcaga caggagttgg aaagtccact
    12001 ttgctaaacc gtatcgcacc agagctagct cttgaaacgg gtgatatttc agacagtctg
    12061 ggacgaggac gccacaccac tagagctgtt agcttttatg acgcttataa tggcaaaatc
    12121 gcagacaccc ccggcttttc gtccttggac tatggcattg ataatgctga ggatctcaac
    12181 gaagcctttc cagagcttag acgccttagc catagctgta aatttcgctc ctgtacccat
    12241 actcatgagc ccaagtgtgc ggttaaggaa gccttgggaa atggtgagct ctggtctgtt
    12301 cgctatcaga attaccttca atttctgagt gaaatcgaaa accgtcgaga aacatatcaa
    12361 aaagttagta aaagaaagta ggtttaacta tgtcatctct gaaaattgcg ccatctattt
    12421 tagcagccga ttatgcttgc tttgctgctg agctggctcg tattgaaaaa acagatgctg
    12481 aatacgttca tattgatatc atggacggtc agtttgtgcc aaatatcagc tttggagcag
    12541 atgttgttgc tagcatgcgc aagcacagca agctagtctt tgattgccac ttgatggttg
    12601 tgaatcctga gagatatgtt gaggcctttg ctcaggcagg agctgatatc atgaccattc
    12661 atgtggagag cactcttcat agtcatggcg ccttgcaaaa gatcagggct gccggcatga
    12721 aggctggtgt ggtcattaat cctgggacac ctgtctctgc ggttgagcct ttattaagct
    12781 tggtggatca ggtgctgatc atgactgtta acccaggctt tggaggacag gcctttattc
    12841 cggaatgtct ggaaaaggtt gcagctattg ctaaaatgag agatgaaaga ggcttgagct
    12901 ttgatattga ggttgacggt ggtgttgatg ataaaaccat tcgtgcttgc tatcaagcag
    12961 gagctaatgt ttttgtggct ggctcctatc tgtttaaggc agcggatttg gcagctcaag
    13021 tgcaaacatt gagggcggcc cttaatggtt aaggtagccc tctttgcagg tggggatttg
    13081 tcctatttta cctgtgattt tgattatttt gttggaattg atagaggaag tctatttttg
    13141 ttagaaaatg ggcttccttt gaatatggct gtaggcgatt ttgattcaat tccccaagta
    13201 gcctttgagg ttgtcaagga gcaagcagag cttcttgttc aggctagtcc tgaaaaaaat
    13261 gatacggaca ctgaattagc tctcaaagag gtatttaccc gttttccaga ggcagaggtt
    13321 acgatctttg gtgcttttgg cggtagacta gaccacttgt tatccaatgt ctttttacca
    13381 gcggatccag agcttgcacc gtttatggca caaatttgcc tgcgggatca gcaaaatgcc
    13441 attagctatc gatcctctgg ctggcagacg attaggcagg ataaggacat gacttatgtg
    13501 gcctttatgg ctgatggtga tgctgacttg accattacag gtgccaaatt tgatttgacg
    13561 acgtccaatt tctttaagaa aaaggtatac gctagcaacg agttcattga tcagcctatt
    13621 aaggttcatg tgccaaaggg ctatttaatt attattcaga gcaaagatag gagttagtat
    13681 ggaccttatt cttttcgtgt tagtgcttgt gttgatagga cttgctgcct attcatttgt
    13741 tagcataaag catttgcaga gcagattaga aaaagcctta gacgataatg ctgataatct
    13801 atcagatcag ctaacctacc agctggatat ggcaaataag agtcagctgc tagagctatc
    13861 aacagtgatg aatcgtcagc aaaatgagct ttttcagcag ctgatggtta ttcgtgatac
    13921 gctgcatcag ggcttggctg aaaatcgcga ccgctcagac cagcgtttgg aaacgatgac
    13981 tcaaagcctt agccaagctg tcaagaacct acaggattct aatgaaaagc gactggagga
    14041 aatgcgccat acagtcgaag aaaagctaga aaagacattg aagaatcgat tgcaaacctc
    14101 ctttgaggcc gtttcaaagc agctagaaag cgtcaatcag ggtctaggag aaatgcggac
    14161 cgtagccaaa gatgttggta ccctaaacaa ggtcctatcc aataccaaaa ccagaggaat
    14221 cctaggtgag ctccagcttg gtcagattgt tgaggacatc atgacagcta accagtatga
    14281 aagagagttt gccacagttt ctggctcaag cgatcgtgtc gaatacgcta tcaagctacc
    14341 tggaaatggg caaggagact atatttacct acctattgac tccaagtttc ccttggagga
    14401 ttattacagg ctggaggacg cctacgaggc tggtgataga gctgctattg agactagccg
    14461 aaaggctctt cttgcggcga ttaaacgttt tgctaagagt attcatagta aatacctgaa
    14521 tccacctgaa acaaccaatt ttgggattat gtttttacca accgaggggc tctactcgga
    14581 ggtggtgcgc aatccggctt tctttgatag ccttcgtcgc gaggaaaata ttgttgtagc
    14641 aggcccatca accttatcag ccctgcttaa ttccttatct gttggcttta aaacccttaa
    14701 cctgcaaaaa aacgcagacg atattagcaa gattttaggc aatgtcaaat tagaatttga
    14761 aaaatttggc ggcctgcttg ctaaggcgca aaagcagctc aacactgcta accataccct
    14821 agaccagctg atgtcaacca gaaccaaagc gattgttcgt gctctggcta ctgtcgaagg
    14881 ctaccaagac cagtcaaccc aatccttatt acatataccc ttattagaag aggcagacga
    14941 tgaagattaa ccaaatgaaa aaagaccagc cttttgaagg cttttacctg ataaaatcag
    15001 cagaagtcag aaaaacaagg gctggcaagg attttattgc ttttaccttt caagatgata
    15061 ctggtgagat ttcaggtaat ttgtgggacg cccagcccta taatgttgag gaatttgtcg
    15121 caggtaagat tgtctttatg aaaggccgtc gtgaggtcta taatggcact cctcaggtta
    15181 accagattac cttaagaaat atccggcctg gggagcctaa tgacccaaag gaatttaaag
    15241 aaaaggcacc tgtcagtgtt actgaggttc gtgactacct agatcagatg ctctttaaga
    15301 tcgaaaatgc gacctggcag aggattgtca gagcgcttta ccgcaaatat gataaggagt
    15361 ttttcactta tccagcagcc aaaaccaatc accatgcctt tgaatcaggc ttggcctatc
    15421 atacagcaac gatggttaga ctagcagata gcattggaga tatttatcca gagctaaata
    15481 aaagcctgtt atttgcaggc attatgctgc atgacctagc caaggtactt gagctgacag
    15541 gcccagacaa taccgaatat actatccgag gcaatctgat aggacatatc gccctcatca
    15601 acgaagagat tacaaagacc atcacagagc tgaacattga tgacaacaaa gaagaggtca
    15661 ccgttttacg ccatgtaatc ttaagtcatc atggccaatt agaatacggc agccctgttc
    15721 gtccgcgcat tatggaggca gagattattc acatgattga caacattgac gccaatatga
    15781 tgatgatgtc aacagctctc agtcgtattg gcgagggaga aatgaccaat cgtattttcg
    15841 ctatggataa ccgatccttt tataaaccta aatattagca aggatcataa taaaaaacga
    15901 acattttgca gttgaatgtt cgttttttcg ttatgttatg atataatagt agagaatata
    15961 taaataatgg ggaacatatg aaattaagac gaagtgaacg catggttgtg atatctaatt
    16021 acctgattaa caacccttat aagctaacaa gtttaaatac ctttgccaca aaatatgagg
    16081 cagccaaatc atctatttca gaagatattg ccattatcaa aaaagccttt gaagaatcta
    16141 atattggaga gattgacact ctaacagggg caagtggagg tgtcattttt acgccaagca
    16201 tttcagaggc agaggctcgc tcaatcgtag aagagctgtg tcagcggctt tcagaaagta
    16261 accgcatttt acctggtggc tatatctatc tgtctgattt attaagcaca ccaaagctct
    16321 tgcagaatat cggtcgcatt atcgctaatg cttttaaggg gcaaaaaatt gacgcggtga
    16381 tgacagttgc aactaagggg gttcccttgg ctaatgcggt tgcaaatatt ctgaatgtac
    16441 cctttgtgat tgtcaggcgc gacttaaaaa tcacagaagg ttcaaccgtc tcagtcaact
    16501 acgctagtgc ctcaagttat cgtattgaaa aaatgttttt atcaaagcga agcttaaagc
    16561 caaacagtcg agtcttgatt gttgatgatt ttttaaaggg tggtggtaca atcacaggca
    16621 tgatgagcct gttaacggag tttgatagta cattggtggg tgtagctgtt tttgcagaaa
    16681 atgcacaatc agagcgcgaa caaatgtcct tcaagtcact attaaaggtc tccgaaattg
    16741 atgtcaaaaa taatagggtc gttgttgaag taggaaatat tttcgataaa taaatcgaac
    16801 gtaggtggaa aaataaaagg ggattaatca tggagcaaga aaactcaaga acaaagcatg
    16861 ttaaaagtac cattgctttg acatcaacca ttgccctatt agggacaagc gttggtgtat
    16921 cacatcaggt aaaggcagac gatgctaagt caggcgatgc caatacaagc aataccagcg
    16981 aagctacgct agctaagcca gaaacgcttg aggaggcagt ccttgcggta aaggctacag
    17041 aagaaacact cagtgagcgt aaaaaagaat tagctgagac taatacaaat atcgcggaaa
    17101 cagagggcga aatcgcaaac ctagaagcaa ctaaaaaaga acagatagct gagcttgcca
    17161 aggctgagga gctacttgag acttactcgt ccatgagtga ggaagaccta gccaagtcaa
    17221 ttgaaaagca tgagacagag ctagagacaa ttaacacaga actagagaag gcgactactg
    17281 agagtcaagc tcaggcagag gcagtggcta agcagcaaga aacgatcgca gcagaggcta
    17341 caaaggccga ccagctagct acccagctaa cagcagcaga gcaaaaggtc tcagacctta
    17401 acacgatgat tagccagccg gaagctattg tctcagaagc tcaagctgca aaagaagagg
    17461 tcaagcgcat ttctgatgac ctagcaaagg ctacagcaaa tctagctact gttaaggaga
    17521 cagtccacag ccagctaacc tcagacctag cagccaacaa ggcagccctg gcagctaaag
    17581 aggcagagct gcaaaggctt caaaatggag ttgccactgc ccaattgaac gttgctggca
    17641 gcaataaatt aattcttcca aaagactacc caattgagga gattaaaaag ctagcagcca
    17701 gtggttatat cggaacagca gcatataatc aatattatca ggcagttaag gatacaatga
    17761 ttgcaaaggc agagccgggt gctgccatga atcagtatgt tgatattcct gaggacctca
    17821 atcgtgttgt tgaccctgac aacctatcac aagaggttca aaatgagcta gctcagtttg
    17881 cagctcaaat gattaatgat gtccgcaagc agctaggact tgtccctgta acagtaacag
    17941 tcggctcaca ggagtttgct cgcctgctaa ccaagagcta caaggaaaca catcaaaata
    18001 ctcgaccttc ctttgtctat ggacaagtag atgcttcagg tcatcgcggt gtaggtccgc
    18061 atgatcaaac gattattgaa gaatctgctg taaaggtagg acttcgtcaa aaagatgaca
    18121 acatgtacga aaaccttggt gcctttaacg aggttcacac tgtcaacggt atcaagcgcg
    18181 gcatctatga cagcattaag tatatgctgt ttacagatca cctgcatggg aacacctatg
    18241 gtcatgctgt taacttcctg cgtgttgata agactgaccc taatgcacct gtttacctag
    18301 gattttcaac aagtaatgtt gagtccttaa atgagcattt tgtgattttc ccagagtcag
    18361 atattgtgga cgctactcgt tttagcacga ctgaaattcc aaaatcaggt caggtgattg
    18421 atcgctcagc aagcatacag gcattgacaa atgatattgc ttcgatcaag ggcaagattg
    18481 cgtctcttga aagcagatta gctgatcctt cctcagaagc tgaggtcaca gctgcgcagg
    18541 caaaaatcag tcagctgcaa catcagctag aagcagccca agccaaatct cataaattgg
    18601 atcaacaggt tgagcaattg gccaatacaa aagattctct acgcacacag ttgcttgctg
    18661 ccaaagaaga gcaggcacaa ttgaaggcta atctagataa ggccttggcc ttgctagcgt
    18721 cttcaaaggc tacgcttcat aagcttgaag cagctatgga agaggctaag gcaagagtag
    18781 ccggcttagc tagtcagaag gctcagcttg aggatctgct agcctttgag aaaaatccta
    18841 atcggatcga gcttgcacag gaaaaggtag ccgcagccaa aaaggcttta gctgatacag
    18901 aggataagct cttagctgct caggccagcc tgtctgattt gcaggctcaa agagcaagac
    18961 tccagctttc tattgcgaca attgaacaac aattagtact attgaagaat ttagtccaag
    19021 aaaagcaaag gctcagactt gaggctgaaa ggctaaatag catgtcagaa acaagacagc
    19081 ttctcaatca gctagcgccg caggctgcaa aagcaggtgt cggctcagaa ttggttgcta
    19141 caggtcttct tgtctccaag gttgcctcag ctatcgctaa gcaatcaccg acaagccatt
    19201 cctatggagc aggagcagca tcacatgcag ctgttgatga caacacacag cgtgctgttc
    19261 aggctggtat ggtcatgctg gcagctgccg gcttagcaac ggttaagctc aaaaaaggca
    19321 gcaaaaaacg ctaagcctag cttaaaaagc atttgacaca aggtatcgtc tatgttatta
    19381 tattagacgg tactttttac ttttggtctc tcaagagtgt acagagacgt gctgacaatt
    19441 gttgcaaaaa gtgcaccaga tataggctgt caccaagtgc tatatcaacc aaaattaaaa
    19501 aaacaggaga atgtagatgc ctacaattaa ccagttggta cgtaaaccac gtaaatctaa
    19561 aattgagaaa tcagattcgc cagctttgaa cattggctac aacagtcata aaaaagttca
    19621 tacgaagctt gctgctccac aaaagcgtgg tgttgcgact cgtgttggaa caatgacacc
    19681 taaaaaacct aactcagccc ttcgtaaatt tgcgcgtgta cgcttaagca accttatcga
    19741 agtaacagct tatatcccag gtattggcca caacctacaa gagcacagtg ttgtgcttat
    19801 ccgcggtgga cgtgtaaagg accttccagg ggtacgctat catatcgttc gtggagcact
    19861 tgatactgca ggtgttgcag accgtaagca aggccgttct aagtacggtg ctaaacgtcc
    19921 aaaaggataa tagaggaggg ataagaaaca atgagtcgta aaaatagagc gccaaaacgc
    19981 gaagtattac cagatccatt atataactca aagcttgtga cgcgtcttat caatcgtatt
    20041 atgcttgatg gaaaacgcgg aactgcatca tcaatcgttt atgatgcttt tagcgaaatc
    20101 aaagaagcaa caggcaacga tgctcttgaa gtatttgaaa cagctatgga caacatcatg
    20161 cctgtgcttg aagtgcgtgc acgtcgtgtc ggtggttcaa actatcaggt tccagttgag
    20221 gttcgtccag agcgtcgtac aacacttggt cttcgttggt tggtaactgc atcacgtgct
    20281 cgtggtgaac acactatgaa agatcgtctt gctaaagaga ttatggatgc tgcaaacaac
    20341 accggtgcgt cagtcaagaa acgtgaggat actcataaga tggctgaggc taaccgcgcc
    20401 tttgcacact tccgttggta agaataagat acgaaggtgt acagaacgca tagtgaagat
    20461 aggaagcttg acgaagagat ttttatctct aggaaagctt atctttttca cacagcgttt
    20521 agcctgagtt cagttttagg ctgttttagt gtgagacaaa tgctagccca aatcgggaaa
    20581 ttgacgcaga agcgatcatt tccagaagat tttatctttt tggcagacat ttgtcgctaa
    20641 aattcaacta atctaagatg tgagagtgtt aagcaagttc tagacaaact gatctattat
    20701 cttttttgtc agtgacttgc agctcaaact cagttacaat caagatgtat agacaaagag
    20761 agcaagattt taatagaaaa ttctcacctt caagatgagt tattgttttg atcggattgc
    20821 tcttaagtcg ggttttggtt tgcaaacata ctaaatgcta tctatcaaac atatcttagg
    20881 aaacgggtag gcctctgcct atccgttttt aatgaatagt gttataataa gatgtaaata
    20941 aaaaatatag gagaaaaaac ctaatggctc gcgaattttc actagcaaaa actcgtaata
    21001 tcggtatcat ggctcacgtt gatgctggta agacaactac aacagagcgt atcctttact
    21061 acaccggtaa aatccataaa atcggtgaaa cacacgaggg tgcatcacaa atggactgga
    21121 tggagcaaga gcaagagcgt gggatcacaa tcacatctgc tgctacaaca gcgcaatggg
    21181 atggacatcg tgttaatatc attgacacac cagggcacgt ggacttcacc attgaagtac
    21241 aacgttcgct ccgcgttctt gacggtgcag taaccgttct tgactcacaa tcaggtgttg
    21301 agcctcaaac agaaactgtt tggcgtcaag caactgaata cggtgttcca cgtattgttt
    21361 ttgccaacaa gatggataag atcggtgctg acttccttta ctcagtacaa acccttcacg
    21421 atcgtcttca agcaaatgct cacccaattc aattaccaat cggttcagaa gatgattttc
    21481 gtggtatcat tgacttgatc aaaatgaagg ctgaaatcta caccaatgac cttggtacag
    21541 atattcttga agaagatatt cctgaggaat acctagagca agctcaagaa tatcgtgaaa
    21601 agcttatcga agcagttgct gaaactgacg aagatttgat gatgaaatac cttgaaggtg
    21661 aagaaatcac taacgaagaa cttgttgctg gtatccgtaa agcaacgatc aacgttgagt
    21721 tcttcccagt gctttgtggc tctgccttca aaaacaaagg agttcaattg atgcttgatg
    21781 cggttattgc ataccttcca agcccacttg acattccagc aattaaaggg gttaatcctg
    21841 atactgacgc tgaagaagag cgtccagcat ctgatgaaga gccatttgca gcccttgcct
    21901 tcaagatcat gactgatcca tttgtaggtc gtttgacctt cttccgcgtt tactctggtg
    21961 ttcttaacag tggttcatac gtgatgaata cctcaaaagg taagcgtgag cgtatcggac
    22021 gtatccttca aatgcacgct aacagccgtc aagaaattga aacagtttac gctggtgaca
    22081 ttgctgctgc tgttggtttg aaagacacta caactggtga ctcattgact gatgaaaaag
    22141 caaaaatcat tcttgagtct attgaggttc cagagccagt tatccaattg atggtagagc
    22201 ctaagtctaa ggctgaccaa gataagatgg gtattgctct tcaaaagctt gctgaagaag
    22261 atccaacctt ccgcgttgag acaaacgttg agactggtga aacagttatc gctggtatgg
    22321 gtgagcttca ccttgatgtc cttgtagacc gtatgcgtcg tgaattcaag gttgaagcta
    22381 atgtaggtgc tcctcaggta tcttatcgtg aaaccttccg cgcttctaca caggctcgtg
    22441 gcttcttcaa gcgtcagtct ggtggtaagg gtcaattcgg tgacgtttgg attgaattta
    22501 cgccaaatga agaaggtaaa ggatttgagt ttgaaaatgc cattgtcggt ggtgtggttc
    22561 ctcgtgaatt tatcccagcc gttgaaaaag gcttgattga gtctatggct aatggtgtcc
    22621 ttgcaggata cccaatggtt gacgttaaag ctaagcttta cgatggttca taccatgatg
    22681 tcgactcatc tgagactgcc ttcaagattg cggcttcact tgcccttaaa gaagcagcta
    22741 aaacagcaca gccagctatc cttgagccaa tgatgcttgt tacaatcaca gctccagagg
    22801 ataatcttgg agatgttatg ggacatgtga cagctcgtcg tggacgtgtt gatggtatgg
    22861 aagcacatgg tactagccaa attgttcgtg cttatgtgcc acttgcagaa atgtttggtt
    22921 atgcgactgt tcttcgttct gcaacgcaag gacgtggtac attcatgatg gtatttgacc
    22981 actatgagga tgttcctaag tcggttcaag aagaaattat caagaaaaat aaaggtgaat
    23041 aatcacccct aagaggctgt ggatagtatc ccagcctttt tgatgtgtta caacagatgg
    23101 gcggtgcagc aattgatcaa agcaatgaca gaaaaatcaa gccctatcag gcataaacgt
    23161 ttaggaaaag gccttaagaa agcgctttta acaacattaa gcgacacttt tggctgccct
    23221 aaaaagctct ttgctgtctc aatattgatg gagaagcagt cttttgaaaa tgggtaatat
    23281 gtttgcattt tttctgaaat agttatataa tagttacgtt gaagggttgt tgcaggaatc
    23341 tgcaagttaa tcttttcaca ataggtaggg attagtccct ttaataataa ttcttttgat
    23401 tttcataagg aggaaatcac taatggtagt taaagttggt attaacggtt tcggtcgtat
    23461 cggtcgtctt gcgttccgtc ttatccaaaa tgtagaaggt gttgaagtaa ctcgcatcaa
    23521 cgacttgaca gatccagcca tgttagcata tcttttaaaa tatgattcaa ctcaaggacg
    23581 ctttgatggc gacgttgaag tagtagaagg tggatttaac gttaacggta aatttgttaa
    23641 ggtttctgct gaagctaacc ctgaaaacat tgactgggct tcacaagaag tagatatcgt
    23701 tttggaagca actggtttct tcgcttcaaa agctggtgct gaaaagcact tacacgctaa
    23761 tggtgctaag aaggttgtta tcactgctcc tggtggaaac gatgttaaaa ctgttgtttt
    23821 caacactaac cacgaaattc ttgatggtac tgaaacagtt atctcaggtg cttcatgtac
    23881 aactaactgt cttgccccaa tggctaaagt tcttcaagac aaatttggtg ttgttgaagg
    23941 cttgatgaca actatccatg gttacactgg tgaccaaatg actcttgatg caccacaccg
    24001 taagggtgat ttccgtcgtg cacgtgctgc agctgtgaac attgttccta actcaactgg
    24061 tgctgcaaaa gctatcggtc ttgttattcc agagcttaac ggtaagcttg acggtgctgc
    24121 acaacgtgtt ccagttccaa caggatctgt tactgagtta gtatctgtac ttgaaaaaga
    24181 cgttacagct gacgaagtga atgctgcaat gaaggctgct gcaaacgaca gttttggtta
    24241 cactgaagat caaatcgtat caagcgacgt tgtaggtatc cactatggtt cattgtttga
    24301 tgcaactcaa actaaggtat tgacagttga tggtaaacaa ttggttaaaa ctgtttcatg
    24361 gtatgacaac gaaatgtcat acactgctca gcttgttcgt acacttgagt actttgcaaa
    24421 aattgctaaa taatgactag agggcctagt ttacctaggc tcttttttgt gtcatgataa
    24481 aggttgctta tccctcattg gctagcttat tgctgaactt gcacttaggc ttaagctgca
    24541 cataggataa gtttttttgc taacgcttta gtgattagct gttctcagag agggtcattt
    24601 tagaaacctt cttaaggtga tatggctatc aagctgcctt ctttgaactg ctatgcttag
    24661 gctttgagtt taggtcttaa aagctttagg tgagtttttc gttataatta actgcataaa
    24721 gcatggcttt aagctcattt ccagcgcaaa tacctttttt ctttgcaaga tgtcaaagag
    24781 aagtactgta atggctcggg cttatctaca ttttttgctc agctattttt agctgttttt
    24841 tagctatggc tccatgaaat tgtgaagcgt tttcattttt attggttata gtcttgacaa
    24901 tctgaaatga tggtaataaa atgagaggtg gataaataac cgtacttaat aatgtatgga
    24961 atattaggag gattttatga catctaaaaa aattcttaac cttgtgtctt tagggttatc
    25021 gttggtttta atctctggct gtacgacaaa tggagagaaa aaagcagctc ctagtcaaga
    25081 caaggataag caagaaaagg ttgtccgtct aaccaatgat cagctaaggg ctagggaaaa
    25141 taccatggcc acactctggt atcagcagtc tgaagaggct aaggctctct acttacaggg
    25201 gtaccaagtg gctaagcagc gcttagatac attattgagt caagcaactg ataaaccata
    25261 ctctattgtt ttggacattg atgagacagt gctcgataat agtccttacc aggctaaaaa
    25321 tattaaagag ggcacaggct ttacgccgga ttcttgggat aaatgggtcc aaaagaaatc
    25381 agccaaggca gtagcaggtg ctaaggactt cttgcagtat gcaaatgaca agggcgttca
    25441 gatttactat gtttctgaca gaacgactaa gcaagtagag ccgactatgg aaaatcttga
    25501 aaaagaaggt attccagtgc aaggcaagga tcatttcttg ttcttagagg agggtgtaaa
    25561 atcaaaagag ggccgtcgtc aaaaggtgca agaaacaaca aatctagtgt tgttatttgg
    25621 tgacaatttg cttgattttg cagagttttc taagacctct catgaagata gaagaaagct
    25681 tttggatcag ctgcatgcag agtttggcag caagtttatc atcttcccta atccaatgta
    25741 tggatcatgg gaaagcagtg tctataatgg tcaaaaatta gacagtgaag gccaaatcaa
    25801 agcacgtgac aaggctttag aggcttatta aaagccctga tttgcgtgat tgctatgact
    25861 atgttgtggc ttcctgcctg cttaggtgat tgtgatctgc taaaaagagg tttacccaag
    25921 ggatttttca agcgctttga aaaattgtga aatagttaat ttattgtttt cagattttat
    25981 ccttatcaaa agaattgtgt tataatagag tgtactaaaa aatattaagg agtctatgaa
    26041 atggctaaat tgactgttaa agaccttgac ctaaagggta aaaaagtgct cgttcgcgtt
    26101 gactttaatg tccctttgaa aaatggtgtt attacaaacg ataaccgtat ttctgcagca
    26161 cttccaacaa tcaaatacat tattgagcat ggtggtcgcg ctatcctttt ctcacaccta
    26221 ggacgtgtga aggaagaggc agacaaggaa ggcaaatcat tggcgccagt agcgaaaaac
    26281 ttggctgaaa agcttggtca agaggttatt ttccctggta gcactcgtgg ggcagagctt
    26341 gaagctgcta ttgatgctct tgaggatgga caggttcttt tggttgaaaa cactcgcttt
    26401 gaggatattg acggtaaaaa ggaatctaaa aacgatccag agcttggtaa atactgggca
    26461 tcactaggag aaggaatctt tgttaatgat gcctttggta cagctcaccg cgctcatgcg
    26521 tcaaacgttg gtatctctgc aaatgttgaa aaagcagtgg ctggtttcct tcttgaaaat
    26581 gaaattgcct atatcaagga agctgttgag actccagagc gtccatttgt cgctattctt
    26641 ggtggttcaa aggtttctga taagatcggt gtgattgaaa accttcttga aaaagctgat
    26701 aaggtgctta tcggtggtgg tatgacctat accttctacg aagctcaagg tattgaaatt
    26761 ggaaactcac tttgtgaaga ggacaagctt gatgtggcaa aatcacttct tgaaaaatca
    26821 aatggcaagc ttgttttacc agttgattcc aaagaagcaa acgcttttgc agattacact
    26881 gaagtgaagg taactgaggg tgaagcagtt gatacaggct tccttggtct tgacatcggt
    26941 ccaaaatcta tcgctaaatt tgatgaagcc ctgacaggtg ctaaaacagt tgtttggaat
    27001 ggtcctatgg gtgtctttga aaaccctgat ttccaagaag gtacaattgg tgtgatggac
    27061 gctattgtga agcagccagg tgttaagtca atcatcggtg gaggtgattc agcagcggca
    27121 gccatcaacc ttggacgtgc agataaattc tcatggatta gtacaggtgg aggtgcttca
    27181 atggagcttc ttgaaggtaa ggagcttcca ggcttagcag ctcttacaga aaaataagct
    27241 gataccattt cggtgctgtc agtcgcaggc tgctatatgg tctgttaagg gctaagacag
    27301 ctgaaggctc acaaaggtgg cttatgttgc tggcggtgct tatgctaatt gttatgatta
    27361 acaagctgtc aaaggatagg ctagagcctg ctgtaccagt ctatcaggcc ttgctgtcag
    27421 ctactaaatg aatgagtcag aaaaaggtgc tatgtaggtg cctttttctg cgttttgctt
    27481 taggctgata gtgagtttgc ttgaagtcaa gactggcttc atgcaggctt cagagtcttt
    27541 gctaggaatg ctataaggtg ggttctgagc ttatctattt aggatatgtg acaaatgctg
    27601 ttaaaatatg ttacactagc attagcttta atttcaatag aaagtatctg atataggtta
    27661 tgaattatca ttttgatgcc tctaagttaa agttgggcat gcgtacgttt aaaactggct
    27721 tagctgtgtt ttttgttttg cttttgtttc atttttttga ttttcagggc ctgcagatag
    27781 gggccttgac agctgttttt agcttgagag agagctttga taagacgatc tcctttggca
    27841 cctctcgtat tttaggaaat tcgattggtg gtttttttgc gattatattt tacctgcttg
    27901 atactctttt tcagggcgca ttttgggtta ccttggtttt tgttccgata ttgacgatgc
    27961 taaccattat gtttaatgtg gcttttaata atcaatctgg catcatcggt gcagttgctg
    28021 ctcttttaat tatcaccttg tctattccta ctggcgaagc ttttatgtat gttattgctc
    28081 gggtttttga aaccttttgt ggggttttta ttgccattct tgtcaataca gacgtggagc
    28141 tgattagaaa taagtggttg agcaggaagc tcaaaaaatg atgtcagaaa acataacatg
    28201 tgaccttgac agtttattaa aatcaaccta taataggggt gtgaaaggaa gttttcatga
    28261 aagaaaaaga actcagacgc tcaatggcag tctttccgat cggtgcagtt atgaccttga
    28321 cagatctatc tgctcggcaa attcgctatt atgaggacca ggagctgata aagcctgaga
    28381 gaacagaggg caaccgtcgc ttgttttcct taaacgatat ggatagactt cttgaaatca
    28441 aggacttttt ggacgaagga ttaaatattg cggcaattaa gcgagaatat gctgaacgcc
    28501 aggataaatt aatgcaaaag caaaaggtat tgactgatgc agatgtgaga cggatcttac
    28561 atgatgagct tcttaatcaa ggtggctttt ccaccccttc acagcatatt gggaattttc
    28621 gtatctagca tacgactggc atgaaagaaa aaggagattg attaatggca atcacagcag
    28681 ctgatgttcg tcgcgaggtc aaagaaaagc atgtgacctt tcttcggttg atgtttacgg
    28741 acattatggg tgttatgaaa aacgttgaga tacctgcaac tgaggagcaa ttagataaag
    28801 tcctatctaa taaggtcatg tttgatggct cctcgattga aggctttgtg cgtatcaatg
    28861 aatcagatat gtatctctat cctgatttag acacttggat cgtctttcct tggggagatg
    28921 aaaatggaac tgttggtggc ttgatttgtg atatttacac tgctgaaggc aagccctttg
    28981 ctggtgaccc acgtggcaac ctaaaaagag ccttgaagca tatggatgag gttggctatc
    29041 agtcctttaa ccttggtcca gagccagaat ttttcttgtt taagatagat gaagctggag
    29101 aaccaacgct tgaggtcaat gacaagggag gctattttga cctcgctccg attgatctgg
    29161 cagacaatac ccgtcgtgaa attgttaatg tcttgaccaa aatgggcttt gaggtcgaag
    29221 ccagccacca tgaggtagct gtcggtcagc atgaaattga ctttaaatat gcagatgcct
    29281 tgaaggcctg tgataatatt cagatcttta agcttgtggt caaaaccatt gcgcgtgagc
    29341 acgggctcta cgctaccttt atggcaaagc cgaaatttgg tattgccggc tcaggtatgc
    29401 attgtaacat gtccttattt gataaagggg gcaacaatgc cttttatgat gaaaatgata
    29461 agcgtggcat gaagctatca gatgatgcct attatttctt aggtgggttg atgaagcatg
    29521 cttacaatta caccgctatc acaaatccaa cggttaattc ctacaagcgc ttggttcctg
    29581 gttatgaggc tcctgtttat gttgcttggg caggaagcaa tcgttcacct cttattcgtg
    29641 ttcctgcttc tcgtggtatg gggactcgtt tagaattgcg ttcggttgat ccaacagcca
    29701 atccttattt agcacttgcc gttttactag aggcaggctt agatggtatc attaataaaa
    29761 ttgaagcgcc ggcaccgatt gaggctaata tttacatgat gacagcagag gagcgcaatg
    29821 ctgctggcat tgttgattta ccgtcaacac tccataatgc tctaaaggcg cttcaaaagg
    29881 atgaggtcat tcaaaaggct ttaggtgatc atatttacac caacttttta gaggcaaaac
    29941 ggattgaatg gtcttcctat gcgacctttg tttcgcaatg ggagattgat aattacttac
    30001 acaactatta gaaaatcaaa actcactcag ctttttgagt gagtttttta tgcttttatt
    30061 cagcagatat ggttatttat acttatcgtt ccttttatac gctatgagga cagaagtgtc
    30121 tggtttatct atttataaaa ataaaatcaa aaattttcag ataaatctat ttcctttttt
    30181 cagaattatg gtataatcta atttaattat tttaaataac tattttgtta ggaggaaggt
    30241 tatatgacag tactaggaac aaaagcatgt aagcgtctgg gcttagcggc agttacgcta
    30301 gcctctgttg ctgccttgat ggcttgtgga aataagcaat cagcgtcaac agacaaaaag
    30361 agtgagatta attggtatac gccaactgag atcatcacac ttgatatctc aaaaaataca
    30421 gatacctatt ctgctttggc tattggtaat tctggcagta accttttgcg tgctgatgct
    30481 aaggggaaat tacagcctga tttggctgaa aaggttgatg tgtcagagga cggcttgacc
    30541 tatacagcaa ccctgcgaga tggcttgaaa tggtctgatg gtagtgatct aacagcagag
    30601 gactttgtgt acagctggca gcgaatggtc gatcctaaga cagcctcaga gtacgcttac
    30661 ttggcaactg agtcacatct gaaaaacgca gaggacatta atagcgggaa aaatcctgat
    30721 ctagactctc taggggtaaa ggctgatggg aataaggtta tttttacctt aacggagcca
    30781 gcaccacaat ttaagagctt gctgtccttc tctaactttg ttcctcaaaa agaatccttt
    30841 gtcaaggacg ctggcaagga ctatgggaca acatcagaaa aacaaattta ttctggtcct
    30901 tatattgtca aggactggaa tggcactagc ggaaccttta agctagtaaa gaataaaaac
    30961 tattgggacg ccaaaaacgt caaaactgag acagttaatg ttcaaacggt taaaaagcca
    31021 gatacagctg ttcaaatgta caagcaaggt aagctagact ttgcaaatat ttctggtacc
    31081 tcagctattt acaatgctaa taaaaagcat aaggacgttg ttccggttct tgaggcaaca
    31141 acagcctata tcgtatataa ccagacagga gctattgaag gcttgaacag tcttaaaatt
    31201 cgtcaagcct tgaatttggc aacagaccgt aagggaattg tatctgcggc tgttgataca
    31261 ggctcaaagc cggctacagc gctggttcct acaggtcttg ctaaattatc tgacggaaca
    31321 gatctaacag agcatgtggc acctggctat aaatacgatg acaaggaagc tgcaaagctc
    31381 ttcaaggaag gcttggcaga gctgggcaag gatgccttga caatcaccat cacagctgat
    31441 gctgatgcgc cggctgccaa gtctgcagtg gattacatca aggaaacctg ggaaacagct
    31501 cttcctggct tgaccgttga agagaaattt gttcctttca agcaacgtct tgaggatact
    31561 aaaaaccaaa actttgaggt tgcagttgtt ctttggggtg gtgattatcc aaaagggtct
    31621 accttctatg gcttgtttaa atcagggtct gcttataact atggtaaatt tacgaatgca
    31681 gactatgatg cggcctacaa caaggctcta acaacagatg ccttgaatac agatgcggct
    31741 gctgatgatt ataaggcggc agaaaaagcc ctttatgaca atgcccttta caatcccctt
    31801 tacttccgta gcggtgaagg cctgcaaaat ccaagcatca aaggtcttat ccgtaattca
    31861 actggtctaa atgttgactt tacttacgct tataaggact agcaataata ttattgtaag
    31921 cctatactga cctagcaagg ccacagctcc ttgatgggaa gtgtttaaga gaagcttagg
    31981 gctagctagg agtgtctatc ctgtaggcct tggcaagcat attgcaagaa ttggtcttaa
    32041 ccagttcttg cttttggtta gaggaaaaat atgattaaat atcttttgaa gcgagtggct
    32101 attttagtag tgacactctg ggtggtgatt accctgtcct tctttttgat gcaggtgatg
    32161 cctggaacac cctataacag tcctaaatta actgatgaca tgattgctat gctgaatcag
    32221 cagtacggct tagataagcc tctttggcag caatatttga agtatttgtt tgatattctt
    32281 catggtgact ttggcaccag ctatcagtcg attaatcaat cagtgacaac cctgatctcg
    32341 cagcgtctgg gggtatctgt gcacttagga gtacaggcgc ttattgttgg tattagctct
    32401 ggcttagctg ttggtgctgt ctcagcgcgg aataaaaata atagcattga tgccatttta
    32461 agtgttatct caacgcttgg tatttccatg ccgtccttta tcattggctt gctgctgctg
    32521 gattatttgg gctttaaatg gaatttactt cccttgtctg gctggggaag ctttgggcaa
    32581 acgattttgc cgacgcttgc tttagctatt ccggtctttg ctcaggtgac ccgttttttc
    32641 cgcagcgaga tgatcgagac cttatcgaca gattatattc agctagctag ggcgaagggc
    32701 ttgactaagc gtcaggtgac tcgtcggcat gcttaccgca attcgatgat tcctgtgtta
    32761 accttggttg gtccgatggc tgctggtatt ttgacgggat cagccctgat tgagcagatt
    32821 ttttccattc cggggattgg gcagcagttt gtgacctcta ttcccaccaa ggattaccca
    32881 gtgattatgg gaacaacgat tgtctatgcg ctaatgctga tggttgctat tttggcaact
    32941 gatatgatca ttagtatcgc agatccacgt gttcgtttgg gataggagag tgctatgcta
    33001 gaagaaacaa aatcatttaa gcttgttgga gcaggtagct tagcgacaca agaaaaaatt
    33061 gaaaagccgg cgctttcctt tcttcaggac gcttggcgta ggctaaagca caataaacta
    33121 gctgttattg cgatggggtt tttagctgtg ctgcttttgt tttctattgg ttctttattt
    33181 gttgtatcta cagatgatgc caatagcttt aacagtaagg aggtaagcat ataccgtaac
    33241 ctgccgccaa agctaagcag cagcttgcca ttttggaatg ggaccattac ctacgctggt
    33301 aatacagagc ccaatgacgc ttatgcggat caaggggtcc cagaggacaa ggccttctta
    33361 ctcgggacgg ataatctggg gcgcagtatt ggaaaacgta ttacggtagg gattcgtatt
    33421 tctcttttga ttgctattgt cgcaaccctg atcgatctag tgattggggt aacctatggc
    33481 ttggtctcag gctttgttgg tggcaagact gacatggtga tgcagcggat cattgagatt
    33541 atctcctcta ttccaaacct tgttattgtg accatgcttg gtcttttgct tggcaatggt
    33601 gtgacttcaa ttattatttc aattgcgatt gtaggctgga cctcaatggc taggcaggtc
    33661 cgcaacctaa ccctgtctta tcgagagcgt gatttcgtcc ttgcttctcg tgccttggga
    33721 gaaagtaata tcaggattgc ctttaagcat gtattgccaa atatttcagg gattattatt
    33781 gttcaaatca tgatgactgt tccgagtgct atcatgtatg agtcagtttt atctgcgatt
    33841 aatttaggcg ttaagccacc gacagcttcg attggttcat tgattactga tgcacaagaa
    33901 agcctgcaat attatcctta tcaggtgctg ctgccggctt ttgccttggt gttaatttcg
    33961 ctagccttta ttttgttggg tgatggcttg cgtgacgctt ttgatccaaa atcaagtgat
    34021 gaataggggg aaataaaatg acgaatgaaa ccattttaag tgtcaaaaac ctccatgttg
    34081 attttaaaac ctacgctgga gatgttaagg cgattcgtga tatcagcttt gagctaaaaa
    34141 agggagagac tcttgcgatt gtgggagaat caggctcagg gaaatctgta accactcgca
    34201 cgctgatggg gttaaatgct aagaatgcaa gtatttcagg gaatatttgc tttaagggca
    34261 agcagctcaa tgagctgaag gaggaggaat gggtcaaggt gcgtggcaat gaaattgcaa
    34321 tgatcttcca ggatccgatg accagccttg atcctaccat gacaattggc atgcagattg
    34381 cagaggcaat aatgattcat caaagcattc ataagacaga agccttgaag cgtgctttag
    34441 acctgatgcg tcaggttggt atcccaaatg ctgaggagca ccttaaggat tacccacatc
    34501 agtggtctgg gggcatgcgg caacgggctg ttattgccat tgctctagct gccaatcctg
    34561 atattttgat tgcagatgag ccgacaacag ctcttgatgt taccattcag gcccagattt
    34621 tgaagctgat gaaggatatt cagtctcaga ccgcatcatc gattatcttt attacgcatg
    34681 accttggtgt tgttgctgga atggtagatc gcgttgctgt catgtatgct ggaaagattg
    34741 tcgaatatgg aacggttgac gaggtatttt atcatccgca gcacccttat acctggggct
    34801 tgctcaattc gatgccaaca acagctactg cagcaggtag cttgaggtct attcccggaa
    34861 cgccgccaga tttattaaac cctccaaagg gagatgcttt tgctgcccgt aatgagtttg
    34921 ccctagacat tgaccatatc aaagagcctc caatgttcaa ggtaagtgac agccactacg
    34981 cagcaacctg gttgctagat gagcgtgctc ctaaaataac ccctccattc ccaatccgca
    35041 agcgttgggc aaaatggcag gaaatggaag agaggaaggc ttaatgacag aagctcgtaa
    35101 aaaattaatc gaagtaaaga atgtttcctt aacctttaac aaggggaaga aaaacgaggt
    35161 taaggctatt gatcgcctta gctttgacat ttatgagggg gaagtatttg gccttgttgg
    35221 ggaatcaggc tcaggcaaga cgacagttgg tcgagctatt ttgaaactgt atgacattag
    35281 tgatggtgag attatcttta acggagaaaa tgtctcccaa ttaaaaggga aaaagctgca
    35341 tagctttcgt aagcatgcac aaatgatctt ccaagatcct caggctagtt tgaacggccg
    35401 tatgaaaatt agagacattg ttgcagaggg cttagacatt catggcttga cagcctcaaa
    35461 ggcagagcgt gaagcaagag tccaggagct gttaaagctt gttgggctca atcagaacca
    35521 tttgacgcgc tacccacatg aattttccgg tggtcaacgc cagcgaattg gcattgcgcg
    35581 tgccttggct gtgaagccga cctttattat cgcagatgag ccgatttcag cgcttgatgt
    35641 gtcgattcaa gcacaggtag tgagtctcat gcagcaattg caaaaaaagc gtggcttgac
    35701 ctatctcttt atcgctcacg atttgtctat ggtcaaatac atttcagacc gtattggtgt
    35761 gatgcattgg ggcaaaatgc ttgagattgg gacatctgat gaggtttaca atcacccgat
    35821 tcacccttat acgaaaagct tgatctcggc cattcctgag ccggatcctg aaaaggagcg
    35881 taagcgtatt gcagaggttt atgatcctag ccaggagcta gatggccaag agcgacaaat
    35941 gcatgaaatc actcctgggc attttgtctt agcgactcag gccgaagccg agcagtaccg
    36001 agcagagtgt ggcctttaag agactagcat aacagcaatt tcctaaaaag gctgatgtga
    36061 tagtttttta ggtatgacag accaaaagtc gtatgacctt tgccgatcaa aagcaggtgc
    36121 catgcgattt tggtggtatg gtggagcttt gtcagccaac ctagactgca caaaaagctc
    36181 cttatgatag aatttgtagc atgaggttgc gacacaagtc taccctaaaa taaaacaaaa
    36241 taaaacaacc gaacaggtct agctttctga gatttcaaaa gccagacctg ttcggttttt
    36301 aatgaatgag actaggtcat aaagtatctt agttaagatt gtctaaagtg cagctctttt
    36361 tgctgtgctt gctgctgttt ttataaaatg actcgtggga atcaatcagc ctgtagtcaa
    36421 atgttatcgc tctctttttg agatgtggct tgacaggttt gctaagctca gcaggctatt
    36481 tttagtagta tagctagaca aaggccctta agctagctca gcacgtcact ctgttaagct
    36541 tagctaacag cacgtgttgg gcaagtagta tgcctcatag ccttgtacgt cagtcattga
    36601 cgttgacgca acaaaaaaac acgagtctct aagctcgtgt caaagatcta ttggctatca
    36661 ggcgttagaa ccatcggaat gataataggc tcgcgctctg tcttttcgta aaggaaggga
    36721 cgaagcgcat taacgatagc accattgaca gactggatac tagcgtcctt atttttcaga
    36781 gcgatacgaa tcgcattgaa aagcacgcgc tgactctctc tgatgagctc gcctgactcg
    36841 cgcatgtaga taaagccgcg gctgagaata tctggtccgg ctaagatcat ctgtgtctca
    36901 aaatcaacag tcgccactgc aaggacaacc ccgtcctctg aaagatcacg acgatcgcga
    36961 aggactgctg tcccaatatc tccaatgcca ttgccatcta cataaatgtc ctgagcattg
    37021 aaatgaccgg ctatacgagc gctatcactg gtcaaggcca atacgtcacc attttccatg
    37081 ataaagatat tttcctctgg aatcccaata tcaacagcaa gcccagcatg aaccttctgc
    37141 atacggtatt caccatggac aggcataaag tattttggct taataaggct aagcattagc
    37201 ttttgctcct gctggccacc atgaccggag gtgtggatat tgttgacctt tccatgaata
    37261 acgtcaactc cagcctcctg aatcgtattg attagcttat tgacgctgac ggtattacca
    37321 ggaattggac ttgatgaaaa gatgacagtg tctccaggct gtaagctgac ctgtctgtgg
    37381 gtaccattgg caatcctagc aagggcggcc atagactccc cttgactgcc ggtacacatg
    37441 atcaaaatct cactagcgtg gtaatgttta atctcattag gctcaataaa ggttcccttt
    37501 gggaccttga tgtagccaag ctcaataccg ttaacaatag ccttttccat tgaacgacca
    37561 aatacagcaa tcttacgccc tgtcttaaca gcggcttctg cagcctgctg caagcggtag
    37621 atatttgaag caaaggaagc aaaaatgata cgtccatgaa tgccttcaat aatgttcatg
    37681 attgactggc caacgacctt ttcagaattc gtaaaggttg gtatctcggc atttgtcgaa
    37741 tcggacaata gacaaagaac cccgtcctta ccaagagcag ccatgcgatg tagatcagcc
    37801 ggatcaccaa caggtgtaaa gtcaaacttg aagtcgccag tacagatgac tttcccttgt
    37861 ggggtgtgga taacaatccc aagtggctct ggaatagagt gagttgtttt aaagaaggta
    37921 acgctcatat gcttaaaggt gagctcggta ttgtgattaa tctcatagag cacagcatcg
    37981 cgtaagagac cgtgctcctc cagctttcct cggataagag ctagagctaa ggggcctgca
    38041 tatataggca cattagcttg ctttagtaaa aaaggaatac cgccaatatg atcctcatga
    38101 ccatgagtaa tcacaagagc cttgacgcgc tccaaattgt caacaatata agagtaatcg
    38161 gggataacat agtcaatccc tagcagatcg tcctctggga atttgatacc ggcatcgaca
    38221 atgatgattt catcttgata ctcaataccg taggtgtttt tgccgatctc tcccagacca
    38281 ccaatcgcat aaaccccaac ctcattaggc cttaaactga tatttgtcat gttaaaactc
    38341 cgttaatgtg aaaacaccag tttctttttc gtagtctagg tgcttgtctg agagcagctc
    38401 gatgaattcg acattgtaat cggtgtgctc ttcaaccatc ttgcgggctt tgatacgccc
    38461 ctcaagctca cttgcagcgt ctatatctag gtatagggcc tgtgtgtttt cacgacgcgg
    38521 actgcgttcc tttgtttctt ggtagaaaac tttataaatc attgatgata tcttcctttc
    38581 atgatgaatc gattatccaa acaataacaa ataggtcaaa acgagaaggc ctctgttttg
    38641 acgattacct atcatgtgat tattgtgtaa tagatttaaa cctgattctg tgcaattact
    38701 aagattatac catactatcg gcttttagta aaaagtttcg ataaaattat tctcttgacc
    38761 ggtgatgagg ctgtggctgt ctccttttcc atgaccttta ttttatgtta taattgtgga
    38821 atagaaatga cttgagaagg gcttagtatg aagacacttg catttgacac atcaaataag
    38881 gcattatctg ttgctctatt agacgatggc acattattgg ctgatcttac gattaatgtt
    38941 aagaagaatc acagtattag tctgatgccg gctattgatt ttttaatgtc ctcagctgac
    39001 ctgaagccaa aggatcttga tcggatcgta gtagcagaag ggccgggctc ctatactggc
    39061 ttgcgtgttg ctactgctac agcaaaaatg cttgcttata gcctaagtat tgacctcgtt
    39121 ggcgtatcaa gcctatatgc cctagcggct tctacttgcc gagaaaaccc tgatagcttg
    39181 gttgtccctt tgattgatgc tagacgacgc catgtttatg tgggctatta tcaccatcaa
    39241 aaagctgtga aacaggataa gtacgcgtcc tttgatgctg ttttagcaga actggtctct
    39301 tgtgaccatg tgatttttgt tggagaagtg gagggctttg cagaggacat tcgatcagcc
    39361 ttgccagagg ccaagataaa gccaagtctg ccatcggctt ttgaggttgg tttgctaggc
    39421 agcagccttt cagctgacaa tgtagcagcc tttgtcccac aatatttgaa gcgggtcgag
    39481 gcagaggaaa actggctcaa aactcatgct gccggtgatg acagccagta tgtcaagcga
    39541 gtttagcgat gatgtctatc caagaaaaag cagcagctgt ctatcaggtg ctaaaagagg
    39601 tctatggtca atccccttgg accttaaagc agatagtgtc tgatatgcag caggagcatg
    39661 ttgattattt taccttttat catcaggaga ccctgctagg ttttttagcg attcaacagc
    39721 tgccaggaga aatggaaatc actaatctag ctgttttgcc aagctatcag gggcaaggga
    39781 ttgcctcttg gctcatggga cagctagatg gctttgaggg agtgatattt cttgaggtta
    39841 gagcgtcaaa ccatagggcg cagcagcttt accttaagca tggctttgag gtggtaggcc
    39901 agcgtagcaa ttattatcat gatccaatag aagcagcctt gatcatgagg cgggaaggaa
    39961 agaatgacag atagatatat tttagcagtg gagagctctt gtgatgagac aagtgttgct
    40021 atcttaaaaa acgacaacgt cttattgacc aatattattg ctagtcaggt tgaaagtcac
    40081 aagcgttttg gtggagtggt tcctgaagtg gctagtcgtc atcatgtgga ggtgattacg
    40141 acttgctttg atgacgcact caaggaggcc cagcttgagg cttctgactt gactgcggtt
    40201 gcggttacct atggaccagg tctggtgggg gccttgctag ttggcctagc agcagccaag
    40261 gcctttgctt gggctaatga tttgcccttg attccagtca atcatatggc agggcacctg
    40321 atggcggcac gcgagcaagg agagctggaa taccctctta tggctctctt ggtttctggt
    40381 gggcatacag agcttgtcta tgtgaccgag ccaggagaat atcatattgt tggagaaaca
    40441 cgtgatgacg cagttggtga ggcctatgat aaggtaggac gtgtgatggg cttgccctat
    40501 cctgctggtc gtgagattga tcagctagct caccaaggga cagataccta tcattttcct
    40561 cgtgccatga tgaaagagga tcatttagaa ttttcttttt caggcctaaa atcagccttt
    40621 atcaacctgc accataatgc gcagcaaaag ggtgaggagc ttgtgcttga ggatctctgt
    40681 gcttcctttc aggctgcggt gttagatata ttgttagcaa aaacgaagaa ggcactcaag
    40741 cagtatccat caaaaatgct agtcgttgca ggtggagtgg cagctaatca gggacttcgt
    40801 gagcgtttag ctgaggaaat aactgatata gctgttgtga taccacctct aagattgtgt
    40861 ggagataatg ctggtatgat tgcgttggcg gcggtggttg agtacgagaa agggcatgtg
    40921 gcaggcttgg atctaaatgc taagccgagt ctagcctttg atagctttca tcagcagtag
    40981 tattagtatg aggagattgt catgttttat ttattgcttc ccccattgat ttgcagtgtg
    41041 gtatttttgg ctgtctatat taaggagcca agaacgctgt ggctaggagc tagctttgtg
    41101 acgaccctag gtgttagtct cttgtgtgct atgatttaca ttttttcaat cgaagaaaag
    41161 cttcagggag ttggtatcct agtgctaggt gttattgggt ttcttgcgat tgtatggttg
    41221 atgtctagtc cctttatcct cttgctcttt ctaagcttta atggcattag gctcatcaaa
    41281 agagaggggc tttcctttcg gaatttattg ctgattggct cagcggtgct attgtttgta
    41341 catcctttta tcagcagact attgttagag agtatcggtg attcaaagct tttaaggatc
    41401 atgtatgaaa cgagtgacct cttaatcctt tacctcttgt taatcgtatc agtctacacc
    41461 atctcaagca tgctgaatac cttttacttc agaaaaacca aggaggatta tattattgtg
    41521 ctgggcagcg gcttaaatgg agaccaggtc acccccttgc tagctagccg cattaataag
    41581 ggcattcaga tttaccagaa aaatcctggc agcaagctga tcatgtctgg tggcaaaggg
    41641 gctgatgagc taatagctga gggtgaggcg atgtgtcgct atgcaatcca gcaaggaatc
    41701 aaaagtgaag atatattagt tgaaaaccaa tccagaaaca ccagagaaaa tattctgttg
    41761 tctaagcaat taataccatc tggagcttcc ttttgcttgg tgaccaatcg ttaccacctg
    41821 tttagagcct tattactggc taaggagcta gccttgcctt gcaggtgcta tggggcaaaa
    41881 acaaagctct actttagtat gaatgccttt atcagagaga ttgttggcta tctccaatta
    41941 aagaaaaagc agcacctgct ggcaatgctc atcttaacag taggctatat agccataaga
    42001 gtggtgatga tctatatgct gcacatttga tgtcattggc aaaaaagcta aggctagtca
    42061 cctcgtcttg ggctgaaaaa gtctctctta ggtccttttc tcagatgata tgagcaagca
    42121 gcctttttaa aaaggctaca tctaggattt tatggagcct tagagcttgt tgtgtggtga
    42181 tgttcaatgg aaccaatcac aattgttaca gcaaaaagca ggcctttagg aacgtttgct
    42241 ttgctggtaa gtccttttac ttgcagaggc tggctacacc agccaaaggc taaggcaagt
    42301 gatttagctt gtgatgatca aggagtttta agacgtaaaa aaatagctcg gtatcttggc
    42361 ataccgagct atcatgataa attggcttct atgattacta aatcttaaac aaggtgagtc
    42421 aagcttacca gctagcctta gtgattcctg gtagttggcc tttgtgagct agctcacgaa
    42481 aattgatacg gctgacacca aacttacgca tgtaagcatg gggacggcca tcaattctat
    42541 cacgattttt caagcgattt ggatttgaat cacgtggcaa tttgcgcagt gcttcataat
    42601 caccctttgc tttaagctcg cgacgaaggt cagcatactg ttcaatcagt tggagctgct
    42661 tatggtattt agcaattttt gacttctttg ccattgcttt ctccttctta atatttaata
    42721 atctcagagc gttatcagca ccctgaattt cctcaaccag tcattaatca gttaagaaaa
    42781 catagctcta ttatacacta atttcaatca aatgcaagaa aaatagataa ctgattaacc
    42841 agttgaggca aaaacagcct gccagtgagt ctactgacaa gcctagctta gctttgcgag
    42901 cttcctgcca cccagccaga gcagagggca gctgtaatgt taaagccacc tgtatgagca
    42961 ttaacatcta agacctcacc agcaaagtaa agtcccgcga cctttttgct ttctagggtc
    43021 ttagggttga tttcttttaa gtcaatgcca cccttggtta caaaggattt ggccagagat
    43081 atttttcctg tgattggaat cggtaattgc ttaatcctgt tgacgagctc ctgagtctgt
    43141 gtgggagtta actgctttcc tttttctgga tagccctttg ctaaaaaatc agcgactcgc
    43201 tcaggcatca aagtcttgag cgcattttta agggcctttt cccggtgctg cgctagatag
    43261 ctgagcagct cagctgcgga ggtttgtggc agcaggtcaa gctctgcgat gtcacctccc
    43321 ttaacaaagg aggaaagcct gagagcagcg gggcctgaca acccaaaatg ggtaaaaagc
    43381 aaatcgtgag tgatctgatg tttcccacag ctaagggtca catcagcaag tgaaatcccc
    43441 tgcagagcct tatgtggaaa gtctgttaat aaggggcttt ccgcagcctc tagctcggtg
    43501 acagctatgt taaagtggcg agcaatatca tagccaaagc ctgtcgatcc agtagatggg
    43561 taggacttgc ctcctgttgc cacgataagc ctctcgcagc tgaaggtttg atcaactgat
    43621 ttgaggtaaa aaaggttatt ccgctttttg accgagacaa tctcggtact gatcagcacc
    43681 tgagctccta gtgacttgat tttttgctcc agcgcattga taatcgtctt tgattgatcg
    43741 gtcgtaggaa acatgcgtcc atgatcctct tccttgaggg tcaccccatt ttccttgaaa
    43801 aaggcaatga tgtcatgatt atcaaattgg gaaaagacgc tatagagaaa gcgcccgtta
    43861 ccgggaatgc ccgcgattag ctcatcatgg cttccgctat tggtgacatt gcagcgtcct
    43921 cctccagtcc ctgctagctt tttgcctagg cgcttgtttt tgtcaagtag gagtgtcttg
    43981 tagccatagt agctactaga gatggctgcc atcataccag caggaccacc tccaataata
    44041 atcgtgtcgt atagtatcat gtgcttattt tagcataaca tcaagcgatt taacagtaat
    44101 gtaaactagg ctaaattgac agaattctgg tattgtgtta ctatttttaa taagaatatt
    44161 cagttacagt aataaagagg aaattatggc aatagaaaag acagttagtg aactagctga
    44221 cattttggga gtgagccgcc aggctgtcaa taatcgtgtc aagtccttac cagaggagga
    44281 ccttgataaa aatgataaag gggtcactgt cgttaagcgt agtggcttgg ttaagctgga
    44341 ggaaatctac aagaaaacca tttttgatga tgagccaatt agtgaagaga ccaagcagcg
    44401 tgagctctta gagattctgg ttgacgaaaa aaacactgaa atcactcgct tatatgagca
    44461 gctaaaggca aaggatagcc agctggctgc taaggacgag cagatgcgta ttaaggacgt
    44521 tcagattgcc gagaaggaca agcagctgga tcagcagcag cagctgacag ctaaggctat
    44581 ggcagacaaa gagaccttga agctggagct tgaggaagca aaggctgagg ctgatcaggt
    44641 acgactgcaa gcagaggaga tacagtctga aatgggacct aaaaaaggtt ttttaaatcg
    44701 tttatttggt aaataacagt ataccaagac cctctaaggg tcttttttga ggagagaaga
    44761 atgaaacaat tagaagcata tattgccttt gatatggaat ttaatactgt caatgaggtt
    44821 agtcatatca ttcagctttc agcggtcaaa tggcacaagc atcaggaggt tgacagcttt
    44881 gacagctatg tttacactgc tgttcccctg caaagcttta tcaatggcct gacaggcatt
    44941 acctcagata agatcgtatc agcacccaag gttgatgagg tgcttgatgc ctttaagcaa
    45001 tttgtcggtg acacgccttt gataggctat aatgcacaaa agtctgattt gcctatttta
    45061 gcagcaaatg gcttggatct gtcagcgcaa tatgcagtcg atgtctttga tgaagcctat
    45121 gagagacgaa gcagcgacct aaacgggatt gctaatcttc gcctgcaaac agttgctgat
    45181 tttttaggga taaaaggaag aggacataat agcttagagg acgctcgtat gacagcgcgt
    45241 gtctatgaag cgtttgtgga atttgacgac aataagtctt acctaaacaa acaaaaagaa
    45301 gcgattgcag ataacccctt tgcagctctg ggagggcttt ttgactagca gcgctagtca
    45361 tttctctgaa aaagaaaaat gacctaaggt cagggcttgc ttgtgacctt gggtcatatt
    45421 ctataatgag gacagaaagg aggtgaagga catgtctgat atttactcaa ctggtgagct
    45481 agcaaaagca gcaggtgtca ctgtcaggac agtgcaatat tacgataagc gtgggatttt
    45541 gttgccttcc cagcttactg aaggtggacg gcggatttac accgagtcag atttggagcg
    45601 attgaaaatc atttgcttct tacgggacct agatttttcc attgagcaga ttaagcgcgt
    45661 gctagcagaa gacaatgtta tggcggtgct tgacctcttg ctggtggatc atatccaaca
    45721 gctggaacaa gacttaagga caaaaaagca tcagcttgac acagctgtca agcttttgtc
    45781 aggtattcgc tgctcatcta gtcactctat caaaaaccta tcagacatgt cacttaccat
    45841 gaacaatcaa aaagcttggc gtcgtttgca gttgaaaatg tttagtaata ttgccctagc
    45901 aatattggtt catgtgatgt tagtgttact aactagctat tttcatctat cttggttggt
    45961 atggatagag gctccactat ggataatctt ttttacttta ttgatcgttt attttcgtaa
    46021 acaatttgag tacctatgtc caaattgtca tactattttt gaaccagact ttaaagagtt
    46081 tgccttggca ggtcacacac caaggacccg caggctgacc tgtcctcatt gccatcaaaa
    46141 atcttactgc cttgaattgg ccaaggaaaa ataatggaaa atctccgctg gatacccagt
    46201 ggagatttct tgctattaga atggtagctt gccagcaaag gctcctagag ttttcttagt
    46261 cgcctcatca atttgagcga gggctgcatt gatggcctga gcagtcatat cctgaagtgt
    46321 ctctatatcc tctgggtcaa cgactgcttc cttgaaatca atgctaacca attgcttatc
    46381 acctgtaaag gttgcagtga ccagctcctg agctgacttt cctgtaaatt gcatagctgc
    46441 taggtcagcc tgcttttgtt ccatttgctt ttgaagcttt tgcgcttgct tcatcatgtt
    46501 ttgcatgttc atcataagtt ccaattctcc taagttttga tacttaacta ttataacata
    46561 tcagacaaga cttcaaacat gtgatctttt aaagttaatg aaaaggccct gctagcctgc
    46621 aatgctttga tgtgctagcg actaacgaac aggtcgtttc ctttaaatag agttttcttg
    46681 ttgagcttta tagctggtgc ttgtttttgt gatgagcttg tgtgaggctg tcgttagtgt
    46741 tgttttaggt ggtttgacat caggagcgat taaaaaagtt atcagtttac atttttataa
    46801 taataactta agaattaatt taactttaga ttaatcttac tttatatttg attgctatac
    46861 ttagtccata acataaataa ccaaaaagaa agaggtaatc gttatgacaa caatgactac
    46921 aacaaaacaa tcaaagacaa ctctagcagc tcgttatttg aagcttggtc ttacttcagc
    46981 aatgtttgct ggaggagcct ttctagctct aggctcagca ccggctgtct ctgcttctac
    47041 ccatgctggt aatgatcagc cagcgactca acgcttaact gatcaggaga tctacgaacg
    47101 tgctcaaaag ctagacttgc cagactatgt gagaggctca atctacggta ttctcaacca
    47161 aaactcaagt gttacttatc caaaggatat agcaggtcta gagcagtcag aagctccaca
    47221 accccctgca gctccacagc tcactgacca agatgctcaa aagctggact tgccagacta
    47281 tgtgagaggc tcaatctacg gtattctcaa ccaaaattca agtgttactt atccaaagga
    47341 tatagccggt ttagagcagt cagaggctcc acaaccccct gcagctccac agctcactga
    47401 ccaagatgct caacagctag acttgccaga ctatgtgaga ggctcaatct acggtattct
    47461 caatcaaaac tcaagcatta cttatccgcg cgattattaa gcatctaaga tgattaaggt
    47521 gcacaatcga cgattaaaat gattgatgag ttaatgagat tagaattatt tggctaagtt
    47581 aagaattagt gttatacttg agagagtgta gcactaattt tttaatcaag gaggaagcat
    47641 gacctacaag atattattgg tggatgatga attggaaatt attgatatta acgaacgtta
    47701 tttgcaacag gcagggtatc gtgttaccac tgcaagcgat ggtagtcaag ccttggagct
    47761 ttttcataag gatcagtacg atttgattat cagtgatgtt atgatgccca atatggatgg
    47821 ctatgatttt attggggagg ttttactgga aaagccagat cagccctttc tctttatcac
    47881 tgcaaaaaca tctgagcctg acaagattta ttccttgagc ttgggagcag atgattttat
    47941 ttccaagccc tttagtccac gtgaattagt cttacgggtc aaaaatattt tgaatcggat
    48001 ttatggtaag gctaaccaag ctgactcctt agttattggg gatttggtca tggatcacag
    48061 cactcgaagg gttacagtgg caaatcaaga tctgaatctg accaacaagg cttttgattt
    48121 gttgtggatt ttggccaatc atttgaatca tgtcttttca aaaacagagc tttatgagcg
    48181 t
//
LOCUS       DARYYD010000010        47264 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.010, whole genome shotgun sequence.
ACCESSION   DARYYD010000010 DARYYD010000000
VERSION     DARYYD010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 47264)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47264)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47264
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.010"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            735..2567
                     /gene="lepA"
                     /locus_tag="TV188_000490"
     CDS             735..2567
                     /gene="lepA"
                     /locus_tag="TV188_000490"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEL1533877.1"
                     /translation="MNSQELKKRQENIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKNGQDYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GLDASEAVLASAKSGIGIEDILEQIVEKVPAPSGDVDQPLQALIFDSVYDAYRGVILQ
                     VRVVNGMVKPGDTIQMMSNGKTFDVTEVGIFTPKAIGRDFLATGDVGYIAASIKTVAD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNITDGDMLE
                     VSNPSEFPDPTKVDSIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYHIPLAEIVFDFFDKLKSSTRGYASFDYEIAEYRRSQLVKMDILLNGDKVDALSFI
                     VHRAFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKAIGSVEVPQEAFLSVLSMDDESKK"
     gene            3109..3546
                     /gene="msrB"
                     /locus_tag="TV188_000491"
     CDS             3109..3546
                     /gene="msrB"
                     /locus_tag="TV188_000491"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1533878.1"
                     /translation="MESKEELRQRIGDLAFEVTQHAATERAFTGQYDDFFEKGIYVDV
                     VSGEVLFSSLDKFNSGCGWPAFSKPIQHRMVTNHHDSSHGMRRVEVKSREAGSHLGHV
                     FNDGPKEAGGLRYCINSAALKFIPYDQMEQEGYAEWLGIFDKS"
     gene            3834..4853
                     /locus_tag="TV188_000492"
     CDS             3834..4853
                     /locus_tag="TV188_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEL1533879.1"
                     /translation="MLTSLEKLPGVLLCLLLALPAWYLGSLFPIIGAPVFAILLGMLL
                     ALVYQKRDYTKSGIALTSKYILQLAVVFLGFGLNVTQVLVVGLQSLPIIVVTIVTALG
                     ISYLFKRWLRLPAKTAILVGVGSSICGGSAIAATAPVIDAQDDDIAKAISVIFLFNIL
                     AALLFPALGQMLGLSNHGFAIFAGTAVNDTSSVTATATAWDAIHQSNTLDGATIVKLT
                     RTLAIIPITLGLSIYQTKSRQAHTTEGSFSLRKAFPTFIVFFLLASLITTFAASLGLP
                     MAIFHQLKLLSKFFIVMAMAAIGLNTNLVTLVKTGGKAILLGGICWLAITSVSLAMQA
                     ALGSW"
     gene            5197..5622
                     /locus_tag="TV188_000493"
     CDS             5197..5622
                     /locus_tag="TV188_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HEL1533880.1"
                     /translation="MKRKFLIGSHGRMASGLKSSIDILAGRGQELQVIDAYIDDSDYT
                     EQVLTFIEDVAADEQALIFTDLLGGSVNQKIVTALMDSGKENIFLISNSNLAALLSLM
                     FLKPEEELTKDEIVATINDSQVQLVDLAPATAAEDDFFN"
     gene            5637..6128
                     /locus_tag="TV188_000494"
     CDS             5637..6128
                     /locus_tag="TV188_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1533881.1"
                     /translation="MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQM
                     TLKMAVPNGMKLLIRSVEDSIKVFNDPRAVDKRIFVIVSSIKDACQIAKQVKDLEAVN
                     VANVGRFDKSDPATKVKLASSLLLNPAELEAAKELVSLPNLDVFNQVLPSNSKVSLSQ
                     LIK"
     gene            6146..6955
                     /locus_tag="TV188_000495"
     CDS             6146..6955
                     /locus_tag="TV188_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017644846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1533882.1"
                     /translation="MLVPATMAALAVLICFGGNYLTGQSMMERPLVVGLVTGLLLGDM
                     KVGILMGASLEALFLGNVNIGGVIAAEPVTATAMATTFTIISHIDQKAAMTLAVPIGM
                     LAAFVVMFLKNVFMNIFAPMVDKAAAANHQGKLVMLHYGTWIVYYLIIASISFIGILV
                     GSGPVNAFVEHIPQNLMNGLSAAGGLLPAVGFAMLMKLLWTNKLAVFFLLGFVLTAYL
                     KLPAVAVAALGAVICVISSQRDLELDAITKGAISNQSSFDSKESEEEDFFA"
     gene            6952..7779
                     /locus_tag="TV188_000496"
     CDS             6952..7779
                     /locus_tag="TV188_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1533883.1"
                     /translation="MRSQDNLTKEERKMLRSVFWRSWTMNASRTGATQYHAVGVIYTL
                     LPVINLFYKTDKDKADALVRHTTWFNATMHINNFIMGLVASMEKKNSEDPTFDASAIT
                     AVKASLMGPISGVGDSFFWGILRVIAAGIGISLASTGSAMGAVVFLLLYNIPAFIIHY
                     YSLYGGYSVGAGFIKKLYESGGIKIVTKTSSMLGSMMVGSMTASNVKFKTILTVAAKG
                     AKEAASIQNYLDQLFIGIVPLLVTMTAFWLLRKKVNINWIMFGIMLLGIVLGLLGIC"
     gene            7969..9603
                     /locus_tag="TV188_000497"
     CDS             7969..9603
                     /locus_tag="TV188_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1533884.1"
                     /translation="MEERFKKRLQDDISHHFSHQSLILSILLIGLFLIFSLAPQQIGL
                     YQDLKAVEHSYHQLIRQNKALLTELNQHILTKFVNHQLSSSDLSKQYYHLRNRSQSQS
                     ELLVFDANSHMLFASNQHLGNFFRNAVYMTEVLKKARQRSSFLRISMDNEEGHYLLLI
                     KPIKIDHQVKGYSLLVMNGKDFLQLSHQIASDFVIADQFDNSFAFTNRTFMTSSLNKL
                     DSHFLKGYFIFHEHRAFILRKVALSPSITLYSYRPLIPVSIALLFSLMSSVMIYAILY
                     WKSKALATQIASSNSAAINQMILDMQAISRQEKNAIDLQSQDEFQYLSVQINQMISRL
                     QALHQKTLALEKQNVSFEKRMLEAQFNPHFLYNTLETILITSHYDSDLTEKIVLQLTR
                     LLRYSLDESQEAVCLGEDLAVLESYLLISQIRFEELRYTIAVEPALETLRVPKLFLLP
                     LIENAIKYGLRYRHDLVIEISVRQLADGIYFTVADNGPGISQKRQADIKELLHSEDSH
                     HGLVNSYRRLKHQFIKVELIFCQRDERFLLTYMVKE"
     gene            9607..10392
                     /locus_tag="TV188_000498"
     CDS             9607..10392
                     /locus_tag="TV188_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1533885.1"
                     /translation="MYKLLIVEDEHIIRKWLRYAIDYHALNILVIGEAKDGQQGAKLI
                     AEAKPDIVLTDINMPIMTAFEMFEATKEQSYAKIILSGYADFANAKSAIHYGVLEFLT
                     KPLERQALHDCLLTIIQKLQQQSQEQELSQQQDYLKLPQPNDQLPDVVQEMLSWIHEH
                     YQDKIMIGQLAHDLGYSESHLYHLAKKYLKMTFSDYINQYRLNRAIQLLIAEPDVMVY
                     QLAEAVGIYDYRYFDRVFKKYLGQTVKDFRETVLHQRSDRSSL"
     gene            10416..11426
                     /locus_tag="TV188_000499"
     CDS             10416..11426
                     /locus_tag="TV188_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1533886.1"
                     /translation="MAIVILGVIGSGLYAIWRHQAGPAPSKPRELVVLTPNSQNILTG
                     TIPAFEEKYGIKIRLIQGGTGQLIDRLQKDKDQLHADIFFGGNYTQFESHKELFEPYL
                     SKHIGFVLPDYLLQSEVATPYTLNGSVLIVNNELAKDMVITSYEDLLKPELKGKIAFA
                     DPNTSSSAFSQLTNILLAKGGYTNPKAWSYIKQLIHSMNSIKSASSSDVYQSVAEGKM
                     TVGLTYEDPCVNLLKSGANVSIVYPKEGTVFLPSAVAIVKQSKAKADAKLFINYMLSL
                     DVQRAFGQSTSNRPIRKDAKASQDMKPLDDIITLKEDYDYITRHKKDILERYNQLRKT
                     TD"
     gene            11679..13463
                     /gene="uvrC"
                     /locus_tag="TV188_000500"
     CDS             11679..13463
                     /gene="uvrC"
                     /locus_tag="TV188_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEL1533887.1"
                     /translation="MNELIKHKLELLPDSPGCYLHKDKAGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTELLVSEIADFEFIVTGSNTEALLLEINLIQENMPKYNIKLKDDKSYPFI
                     KITNEPFPRLLITRQIKKNDGLYFGPYPDAYTATEVKKLLDRIFPFKKCKNPVNKVCF
                     YYHLGQCQAHTICHTDKAYWDSLVADVKQFLNGKDDKIIDDLRSKMLEASHNQEFERA
                     AEYRDLISGIATMRTKQRVMSKDLQDRDIFGYFVDKGWMCVQVFFVRQGKLIQRDVNM
                     FPYYNEAEEDFLTYVGQFYSDQRHLIPKEVFIPETIDETLVAAIVPARIVKPQRGEKK
                     QLVALATKNARVSLQQKFDLLEKDLRKTSGAIEHLGQLLGIEKPVRIEAFDNSNIQGT
                     SPVAAMVVFVDGKPSKKDYRKFKIKTVIGPDDYASMREVIYRRYSRVKHEGLQAPDLI
                     IVDGGQGQVKAARDVIEHQLGLSIPVAGLQKNDKHQTHELLFGNPLAVVELPRNSEEF
                     FLLHRIQDEVHRFAITFHRQVRSKNAFSSKLDHIAGLGPKRKQLLLKRFKSMTALEQA
                     SLEEIQQLGIPKTVAEALFDHLTSKSEV"
     gene            13591..14193
                     /locus_tag="TV188_000501"
     CDS             13591..14193
                     /locus_tag="TV188_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEL1533888.1"
                     /translation="MKFLELNKKRHAIKRFNDKPVDYNDLRTAIEVATLAPSANNIQP
                     WKFVIVEEKKAELAKDLPLANKTQVEQAQYVIALFSDTDLIQRSRKIARIGVKSLPDN
                     LIGYYMETLPPRFATFTETQKGEYLAINAGLVAMNLVLALTDQKMASNIILGFNKKLT
                     NEILDIDPRFRPELLITVGYSDDKPEPSYRLPVDEIIERR"
     gene            14274..15683
                     /gene="pepV"
                     /locus_tag="TV188_000502"
     CDS             14274..15683
                     /gene="pepV"
                     /locus_tag="TV188_000502"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEL1533889.1"
                     /translation="MTTIDFKAEVDKRKEAMLEDLSNLLSINSERDDAKADAKHPFGP
                     GPVKALEFFLAMAERDGYQTRNIDNYAGDFEFGQGDEVLGIFAHLDVVPAGSGWETDP
                     YKPVIKDNRIYARGSSDDKGPTMACYYALKIIKELGLPVSKRVRFIVGTDEESGWGDM
                     DYYFAHNGLKNPDFGFSPDAEFPIINGEKGNITEYLHFVGQNAGAFVLHRFQGGLREN
                     MVPESATALISSPHELNVIEASLEQFLSEHAVTGSVKEADGLLEVTIIGKSAHGSTPE
                     AGVNGATLLAKFLNQFSFDGAAKAYLHIAGEVLHEDFTAEKLGLAYTDDKMGALSMNA
                     GVFSFAKDSDDNTIALNFRYPKGTNAAVLKAGLEQLPGLTKVTLSEHEHTPHYVPMDD
                     ELVSTLLSVYEKQTGLKGYEQVIGGGTFGRLLERGVAFGAMFPGDENTMHQANEYMPL
                     DNIYRSAAIYAEAIYELIK"
     gene            complement(15950..17326)
                     /gene="mnmE"
                     /locus_tag="TV188_000503"
     CDS             complement(15950..17326)
                     /gene="mnmE"
                     /locus_tag="TV188_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002888396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEL1533890.1"
                     /translation="MSITKEFDTIAAISTPLGEGAIGIVRLSGTKALDIAKSIFKGKD
                     LTTVASHTLNYGHIIKPSTGEVIDEVMVSVMLAPKTFTREDVIEINTHGGIAVTNDIL
                     QLLIKQGARMAEPGEFTKRAFLNGRIDLTQAEAVMDLIRAKTDKAMSIAIKQLDGSLS
                     QLISDTRQEILNTLAQVEVNIDYPEYDDVEEMTTALLRDKTREFQTLLEQLLRTAKRG
                     KILREGLSTAIIGRPNVGKSSLLNTLLREDKAIVTDIAGTTRDVIEEYVNIKGIPLKL
                     VDTAGIRETDDLVEQIGVERSKKALQEADLVLLVLNASEKLTEQDKALLALSQDSNRI
                     ILLNKTDLEQVIEKDQLPEEAIPISVLQNQNIDLIEDRINQIFFDHTGLIEQDATYLS
                     NARHISLIEQAVQSLEAVNEGLALGMPVDLLQIDLTRAWEILGEITGDAAPDELITQL
                     FSQFCLGK"
     gene            17598..17819
                     /locus_tag="TV188_000504"
                     /pseudo
     CDS             17598..17819
                     /locus_tag="TV188_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
     gene            17942..18256
                     /locus_tag="TV188_000505"
     CDS             17942..18256
                     /locus_tag="TV188_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1533891.1"
                     /translation="MVVLQNNSSTASERATALARGVQALSSAGAVSKDMKTTVTGNRS
                     DASSAIDLSHNVSAQVVGIIASMSQHIQSVSASFQAMDLQLGKELGRLENRRRFSLND
                     PK"
     gene            18261..18593
                     /locus_tag="TV188_000506"
     CDS             18261..18593
                     /locus_tag="TV188_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3958 family protein"
                     /protein_id="HEL1533892.1"
                     /translation="MYQKERLDKRLETIAQELKRNEQRFEDYEELSNLAAQLLTAAAT
                     TFRSSSDSHLFEGALAEECYLKRKTQASLEQSHEELLGEQRRLYQEEEALTRQLKLVK
                     GKERANEH"
     gene            18595..20193
                     /locus_tag="TV188_000507"
     CDS             18595..20193
                     /locus_tag="TV188_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533893.1"
                     /translation="MYLGSSDQQASSVGKVLQQRITAYKSLQRALEQLVSSSPDLSGH
                     TYASAKRYSEQVLIPLMRGCILLDEAIKEACAAFPNDYRRQVDSVDLKESELVDQISR
                     SDRIIGRYVELIDLEYRQELPNYSYITNLKSGASNQRQVKRKLEEKLLKLREFDSNSR
                     HLFSSIAALAEAVNIGIRQTKTSWNGTSQTFTLPRALDLEWTKVVEKRWTQREEKASK
                     LKLQQAAEKLSRETGIKYEDAYRFVMDGVLSDENKNKIKSVKKLVKYTKGGLYIVSSG
                     RYYWKHSGKHYWKNTPNKTWNIWKASKNDPNFDKGGIKGKHFSKKGARYTDLPGIKQL
                     KKSETVQSLISKISKDNQGKLTKVGKGLKKVDKELSNISSKLKSYEHGRLNRDLKMMK
                     ENNLGKSLGKFGKVGKAASKVLKFAGKGLKVAGWVGAAINVKDSVETYKKKGYSNEQT
                     AALTARKVAVDTATTVVGSNIGRVTGAVIGQAVIPIPGVGAAIGSVAGSILGAMAGSW
                     IGSTINDNLDKNVKPKQSGRSLAW"
     gene            20187..20873
                     /locus_tag="TV188_000508"
     CDS             20187..20873
                     /locus_tag="TV188_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533894.1"
                     /translation="MVMLMRTLLFPVDNGLDSGLTGDGYAAEYDLWTGKVTWRQLGDG
                     KIKRQQKVAAIINLIAAAISPLVIMSIIFTAKSLKLFDVDTSTTIYRYAPLMVGLVFF
                     FSFELLMLAIRRLYPLAKEEPSLKRQHGYFKTMYDNTIRENDGVFNNLSVPFIGLYVA
                     FLIAFSVIPIFYSQYLQQNSFWSYLGNLVGSSILISLVPNFLWNVLVKQLIYIKLIRK
                     TKEKILKNET"
     gene            20895..21581
                     /locus_tag="TV188_000509"
     CDS             20895..21581
                     /locus_tag="TV188_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533895.1"
                     /translation="MVMLMRTLLFPIDNGMDNNLIGDGLSAEYDLWTGKVTWRQPSDD
                     KIRTQQKVAFVLNLIAGSLSPLAIFLFVIIVRRLGVFSGDTNSMIFKWAPLIVGFILF
                     ISFELLMLALRSRYTILEKEPDLDRQLYYYRTMYDNTIHDNSGVFNNLSVPYVGLYIT
                     LFLIFLIIPLCYHFYLHPSSFGDYLAALSVTSLLISLFPNFLWNGVLKHVIYVKLIRQ
                     TKERILKNET"
     gene            21603..22280
                     /locus_tag="TV188_000510"
     CDS             21603..22280
                     /locus_tag="TV188_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533896.1"
                     /translation="MVMLMRTLLFPVDNGMGTGLTGDGYAAEYDLWTGKVTWRQATKQ
                     TIEKQQALTSNLLIIASCLSPVTVAGMILLSRSFPIFEEDLSEKIDTYAPIILGVVLF
                     LAFETLMLAIRGRDPLAEKEPDLKRQHDYFEKMFDFAIRRNLSSDNLKTPYIATYFAF
                     GISLLCIPFSYYVYLNPEQFPNLDYGHLSILLVTSILISLVPNFLWNVLLKHIIYIKL
                     IRKTKGQ"
     gene            22287..22601
                     /locus_tag="TV188_000511"
     CDS             22287..22601
                     /locus_tag="TV188_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1533897.1"
                     /translation="MNKPEHILPIGTIVLTETGEIPLMIVSRASLFDDNGEIGYFDYA
                     AVPYPEGIGNDNEYLFFNHEDIADVIYFGYVNSNEQLFAEAYDDLVKTSGYRKLSLDH
                     HQ"
     gene            23049..23732
                     /gene="rpiA"
                     /locus_tag="TV188_000512"
     CDS             23049..23732
                     /gene="rpiA"
                     /locus_tag="TV188_000512"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEL1533898.1"
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRIKEE
                     GLQVVGVTTSSVTTKQAEGLGIPLTSIDDIDCIDLTVDGADEVDKAFNGIKGGGAALL
                     MEKIVATPTKEYIWVVDESKLVDHLGAFKLPVEVVQYGADRLFRVFERAGYKPSFRMK
                     GDKRLITDMQNFIIDLNLGCIENPCEFGRLLDQTVGVVEHGLFNGMVDKVIVAGQAGV
                     TVLEANQST"
     gene            23810..25021
                     /locus_tag="TV188_000513"
     CDS             23810..25021
                     /locus_tag="TV188_000513"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEL1533899.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISE
                     TAGLAVPNMAKIGLGHIPRPVPLKTVPAEADPTGYVTKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWDGFPEEIIQKIEAFSGRKVIREANKPYSGTKVIDDFGPRQMETGELIV
                     YTSADPVLQIAAHEEVIPVEELYRICEYARSITLERPALLGRIIARPYIGEPGSFTRT
                     ANRRDYAVSPFQDTVLNKLADAGISTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTL
                     IKSLQLPAFTKGLSFTNLVDFDASFGHRRDPEGYRDCLHEFDRRLPEIIANMKDDDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSASCTGAGVIPQGHFADISATIAENFGVDTA
                     MIGTSFLADLV"
     gene            25234..26043
                     /locus_tag="TV188_000514"
     CDS             25234..26043
                     /locus_tag="TV188_000514"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEL1533900.1"
                     /translation="MTLLEKIRETQAFLESKGIDKPEFGLILGSGLGELANEVEQAIV
                     IDYADIPNWGKSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPMEVVTFPVRVMKA
                     LGCHSLLVTNAAGGIGYGPGTLMLINDHINMTGTNPLIGENLDEFGPRFPDMSDAYTA
                     AYRETARSVAEKLGLDLQEGVYLGCSGPTYETPAEIRAFKVMGADAVGMSTVPEVIIA
                     AHSGLKVLGISAITNFAAGFQSELNHEEVVEVTERIKENFKGLVKAILAEL"
     gene            26134..26919
                     /locus_tag="TV188_000515"
     CDS             26134..26919
                     /locus_tag="TV188_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HEL1533901.1"
                     /translation="MTDMEHTISILLEVYAYSHAYKIARTLPDFSPKVLYLLELLKER
                     RELNVAYAFQHRAENRLIEDRHQVKLLLNEAQEEEQTANYLLDLAAKVKNGEIIDFVR
                     SVSPVLYRLFLRLLEQAVPDVQSYIIDTKNDQYDTWNFKAMEKADNDLFRSYLAQRQP
                     RHVTTRSLADLLVLSELPADIKRLVVVLRQFEKSVRNPLAHLIKPFDEEELYRTTHFS
                     SQAFLDGLIRLAVFSGVNYIKEPFYFDVVNAVIEKELLDSAKP"
     gene            complement(27052..27960)
                     /locus_tag="TV188_000516"
     CDS             complement(27052..27960)
                     /locus_tag="TV188_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1533902.1"
                     /translation="MRIQQLQYIIKIVECGSMNEAAKQLFITQPSLSNAVKELEQEMG
                     ITIFIRNPKGITLTKDGVEFLSYARQIIEQTALLEDRYKNHNTSRELFSVSSQHYAFV
                     VNAFVSLLKRADMTQYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFEE
                     NHLTVSTLFKTTPHIFISKSNPLANKTSLTIDDLLDFPYLSYDQGIHNSFYFSEEMMA
                     HIPHSKSIVVSDRATLFNLMIGLNGYTVASGILNTNLNGDQIVAIPLDVPDVIEIVFI
                     KHEKANLSKMGERFIDYLLEEISFNH"
     gene            28300..28749
                     /locus_tag="TV188_000517"
     CDS             28300..28749
                     /locus_tag="TV188_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533903.1"
                     /translation="MTGQSSHQVLIQKLLVSTHYLTLFRDELKLVERTPSILGSEFPV
                     SLVQTELGDIITLVDTLNKQQRLIESTFWYEESAFKLMNKALDIVDNWIKGIDGLIKL
                     CQSKEVFQAIVGDKRTRVFGVLIDVFSSLKISTMSLKEFAAPAALCH"
     gene            29370..30062
                     /gene="pyrF"
                     /locus_tag="TV188_000518"
     CDS             29370..30062
                     /gene="pyrF"
                     /locus_tag="TV188_000518"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEL1533904.1"
                     /translation="MREERPIIALDFPSFEEVKSFLSLFPADERLYVKIGMELYYAEG
                     PDIVRYVKSLGHSVFLDLKLHDIPNTVKSTMAVLSRLGIDMTTVQAAGGVEMLRAARE
                     GLGQGPILIAVTQLTSTSEEQMREDQNIQSTLLASVLHYAKRTAQAKLDGVVCSAHEV
                     KAIKSEVPAGFVCLTPGIRPTGADIGDQKRVMTPHQARAIGSDYIVLGRPITQATDPV
                     KAYHQIKAEWNR"
     gene            30122..30757
                     /locus_tag="TV188_000519"
     CDS             30122..30757
                     /locus_tag="TV188_000519"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEL1533905.1"
                     /translation="MTLAAQIATDLLEIKAVYLRPKEPFTWASGITSPIYTDNRITLS
                     YPKTRSLIENGFVETIKAVFPEVEVIAGTATAGIPHGAIVADKMDLPFAYIRSKPKDH
                     GAGNQIEGHVRCGQKMVIIEDLISTGGSVLEAAAAASREGADVLGVVAIFTYELPVAS
                     INFEKAGLSLVTLSNYSDLIKVAKAKGYIDADGLALLKRFKEDQKHWQHES"
     gene            30809..31552
                     /locus_tag="TV188_000520"
     CDS             30809..31552
                     /locus_tag="TV188_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1533906.1"
                     /translation="MTYKDLLEIGETSYYQTDRLTYYKNPVVSERYFDNYLSYRSMPS
                     LADLKKDLAYVAKEQQDYPSHYAFLFFAENEELSTDMRAYLTDHHFSLEKHLIFTNEL
                     AKLHLKERDISPVTIEQLSETSFSAYLAYKYQANLAYGETYANQCKADNEANLLTNGS
                     TIYLAIKEGKIIGDITAWECGDYIEMDDFSVDEAYRGRGIGTALQRKASQGYKKVILI
                     SEEANRAMYEHQGYQEVAYYWTALKTSTR"
     gene            31787..33241
                     /locus_tag="TV188_000521"
     CDS             31787..33241
                     /locus_tag="TV188_000521"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HEL1533907.1"
                     /translation="MIFKDATEMAQAVREGRVSPSALVRDTIKKAQALNPELNAITSE
                     RFSEALAEAAARDFSGKPFAGVPIFLKDLGQEQEGQLATAGSVLFKDYRASKTDYVVQ
                     RLEELGFIILGRSNTPEFGFKNISDSRLHGPVNLPQDKSRNAGGSSGGAAALVSSGIT
                     LLAPASDGGGSIRIPASFNGLIGLKPSRGRVPVGPGSYRGWQGASVHFALTRSIRDTS
                     RLLYHLQVYQVESPFPLVPLTKEELFHPLDRPLRIALYDHMIDGTTASIDAQTALTEA
                     CHFLKEMGHEVVRLDKLPLDIPKVMRDYYLMTSVETAAMFADSQEALGRQVTKADMEV
                     MTWAIYQAGKDILASVYSQALQRWDHYSAEMASFHEQYDLLLTFTANTPAPKHGQFQP
                     SKELIDKLAKAECYPSSQRLALVEAMFEQSLFITPYTALANLTGQPALSLPTYETSAG
                     LPMGIQLIAAKGREDLLLGIARQFERAGLLKLPG"
     gene            33361..34227
                     /locus_tag="TV188_000522"
     CDS             33361..34227
                     /locus_tag="TV188_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1533908.1"
                     /translation="MKKGVALLSVSLASLLLAACGSQPSAQKTSWEKIKDKGVLKVAT
                     PATYQPTSYYNDANELVGYEVDLMKEIGKRLDLKVKFIETGYDQAFTSVDSGRVDVSL
                     NNFDITAKRQKKYNISTPYKYGVGGMIVRADGSSGISKADLSDWKGKKAAGASGTEYM
                     KVAKKQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMKSQNPNLNVKM
                     SDVLYNPTAQGIIMSKKDDTLKKKIDAVIKDMKQDGSLKTISKTYYAGQDLTVPFGKD
                     KKIPVIDASDVD"
     gene            34255..34908
                     /locus_tag="TV188_000523"
     CDS             34255..34908
                     /locus_tag="TV188_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1533909.1"
                     /translation="MLNLRLILESLGFVLSGLPYTLGISFLSFLTGLLLGLLLAFLRR
                     STSHFSHYLVRSYVSIMRGVPMIVVLFVLYFGLPYYGLELSALLCAYLGFSLVSAAYI
                     SEVFRASIDAIDQGQWEAARALGLPYVSIVKHVILPQAFRIAIPPLGNVVIDMVKSSS
                     LAAMITVPDIFQKAKIIGGREWDYMSMYILVAFIYWVIAFLLERCQGFLEKRLRLLS"
     gene            35039..35446
                     /locus_tag="TV188_000524"
     CDS             35039..35446
                     /locus_tag="TV188_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1533910.1"
                     /translation="MADSIVFRKNHMISTQAFARVLEASGIKRPTKDEARLSQMLKHS
                     NYLWTAWEGDKLVGVARALTDYAYVCYISDLAVDQAYQGQGIGKQLLSFISEDLGDAV
                     ALVLLSAPSAMSYYPKLGFEQSDKAFIIPRKPF"
     gene            35458..36111
                     /locus_tag="TV188_000525"
     CDS             35458..36111
                     /locus_tag="TV188_000525"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEL1533911.1"
                     /translation="MTHSAWHDEIKQVLPKDYYRRINRFLDEVYATGVVYPPRDNVFK
                     ALQVTPLEETRVLILGQDPYHGPLQAQGLSFSVPDSIPAPPSLQNILEELAADIGVRN
                     HHDLSSWAEQGVLLLNACLTVPEGRANGHAGLIWEPFTDAVIKVLNAKDRPVVFILWG
                     AYARRKKALITNPIHHVIESPHPSPLSAYRGFFGSKPFSRANAILEKEGLGQIDWLR"
     gene            36343..37617
                     /locus_tag="TV188_000526"
     CDS             36343..37617
                     /locus_tag="TV188_000526"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEL1533912.1"
                     /translation="MLLIKNGRVMDPKSQLDQVADVLIDNGRILRIAPDIEHDEVEQI
                     DASGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGVTTVVMMANTNPVISDTE
                     TLQAVLASAAKEKINIYTNASVTKRFNGQELTDFKALLAAGAVSFSDDGIPLESSKVL
                     KEALDLAKANKTFIALHEEDPQLNGVLGFNEHIAKDHFHFCGATGVAEYSMIARDVMI
                     AYDRQAHVHIQHLSKAESVKVVAFAQQLGAKVTAEATPQHFSKTEDLLRLAGANAKMN
                     PPLRTEQDRLAVIEGLKSGVIAIIATDHAPHHRDEKAVADLTKAPSGMTGLETSLSLG
                     LTNLVEPSHLSLMALLEKMTINPASLYSFDAGYLAESGPADLVIFADKEERLVTEAFA
                     SKASNSPFIGETLKGVVKYTIAKGQIVYQADN"
     gene            complement(37671..38318)
                     /gene="plsY"
                     /locus_tag="TV188_000527"
     CDS             complement(37671..38318)
                     /gene="plsY"
                     /locus_tag="TV188_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEL1533913.1"
                     /translation="MKLILLILTAYLLGSIPTGLWIGQYFYNINLREHGSGNTGTTNT
                     FRILGLKAGAATLLIDIFKGTLATLLPVLVGASNISPITIGFFAVLGHTFPIFAGFKG
                     GKAVATSAGVLLGFAPLYLLFLAAVFVLTLYLFSMISLASLTASVVAVISVLTFPAAH
                     FLLPSYDWLLTITIVVLAAIIILRHQDNMKRIKQQSENLIPWGLNLSKQQPASHH"
     gene            38451..40400
                     /gene="parE"
                     /locus_tag="TV188_000528"
     CDS             38451..40400
                     /gene="parE"
                     /locus_tag="TV188_000528"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEL1533914.1"
                     /translation="MAKKEISITNYNDDAIQVLEGLEAVRKRPGMYIGSTDATGLHHL
                     IWEIVDNAVDEALSGFGNEIDVTLNKDGSATISDSGRGMPTGQHALGIPTVQVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGRPVTGLE
                     KIATAPKSKSGTRVTFMPDDKIFSTTEFKWNTIAERLKESAFLLKTVKMTLTDLRGDD
                     PVVEEFHYENGVQDFVAYLNEDKETLTPVIYMEGQEQDFQVEVALQYNDGFSDNILSF
                     VNNVRTKDGGSHETGLKSAITKAMNDYARKTSLLKEKDKNLEGSDYREGLSAVLSILV
                     PEQHLQFEGQTKDKLGSPLARPIVESIVSEKLTFFLLENGELAGHLIRKAIKARDARE
                     AARRARDESRNGKKNKKDKGLLSGKLTPAQSKNPKKNELYLVEGDSAGGSAKQGRDRK
                     FQAILPLRGKVLNTEKAKMADILKNEEINTMVYTIGAGVGADFNLDDINYDKIIIMTD
                     ADTDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKSEKVSYAWTDGEL
                     EDLRKEFGKGASLQRYKGLGEMNADQLWETTMDPDTRTLIRVTIDDLARAERRVSVLM
                     GDKAAPRRQWIEDNVTFTLEENTVF"
     gene            40502..41317
                     /locus_tag="TV188_000529"
     CDS             40502..41317
                     /locus_tag="TV188_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATPase"
                     /protein_id="HEL1533915.1"
                     /translation="MKLDICQQSYSLQWGGTYYFALTDYPNIKAWELEKLAAFCAYEK
                     WNHRQTDISCQDSKLLEEVHQFLEAHACAYLFRPSCKLVASTFNINGEAVCCPYLSHT
                     CTVAAALSIFKTGRLLSAVRAFGVTAQELARSDRNAAGDPADYFHYVMLGWSNTTSGY
                     RLAMERLLNRMPNEKDLREHFVPGVSFHYSYSDICQMKGYVFDGYHPAKIKDELSLEE
                     LQACIIPKSWQQRFEAIIPKALRSRVHYLDYKGEGLVEWSDRVYQLLRVISDS"
     gene            41792..44251
                     /gene="parC"
                     /locus_tag="TV188_000530"
     CDS             41792..44251
                     /gene="parC"
                     /locus_tag="TV188_000530"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEL1533916.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQERALPDIRDGLKPVQRRI
                     LYSMNKDGNTFEKGYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQDWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIDKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSSGISAGYATDIPPHNLSEVIDAVIYMIDHPNAKLDKLMELLPGPDFPTGGI
                     IQGAAEIKKAYETGKSRVVVRSRTEIEDLKGGKQQIIVTELPYEVNKAVLVKKIDDVR
                     VNNKVPDIAEVRDESDRTGLRIAIELKKDADSQTILNYLLKYTELQVNYNFNMVAIDH
                     FTPRQVGLQKILSSYIAHRKSIIIKRSQFDKEKAEKRLHIVEGLIRVLSILDEIIALI
                     RASDNKADAKENLKVSYDFSEEQAEAIVTLQLYRLTNTDIVTLQQEEHDLRELITTLS
                     AIIGDEATMYNVMKRELREVKKKFAGPRLSELQAESQAIEIDSASLILEEETFVSVTQ
                     GGYIKRTSPRSFHASSLEEIGKRDDDHLIFVKQAKTTDHLLLFTNLGNVIYRPVYELT
                     DLRWKDIGEHLSQAIANFAADELVIYAELIQSFEEGLYISVTQHGLIKRFERKELTPW
                     RTYKSKSIKYAKLKDIDDRIVAIAPIIMEDLLLVTQQGYALRFSSQEIPIQGLKAAGV
                     KGINLKAQDYLVSACPVNADSFFVLTQRGALKRVAIADIPQTSRANRGLPVLRELKTK
                     PHRVFLAGMVKGDTTTGTIDLFTHDSEDTASDQQLEVISKTGQQYQLALNSLSLSDRT
                     SNGSFISESISDQEVAAARLI"
     gene            44349..45374
                     /locus_tag="TV188_000531"
     CDS             44349..45374
                     /locus_tag="TV188_000531"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEL1533917.1"
                     /translation="MMTTAIDWENLGFEYRKLPFRYVSYYKDGKWDAGRLTEDATLHI
                     SESAPALHYGQQAFEGLKAYRTKNGSIQLFRPDRNAARLQATADRLLMPQVSTEQFID
                     AVKQVVKANEDFVPPYGTGATLYLRPLLIGVGDIIGVKPANEYIFIVFAMPVGNYFKG
                     GLAPTNFIVSEDYDRAAPYGTGAAKVGGNYAGSLLPGKAAKTAGYSDVIYLDPATHTK
                     IEEVGAANFFGITANNEFITPLSPSILPSITKYSLLQLAEERLGMTAIEGDVPINDLD
                     RFVEAGACGTAAVISPIGGIQYQDKLHVFYSETEVGPVTRRLYDELVGIQFGDIEAPE
                     GWIVAID"
     gene            45442..45672
                     /locus_tag="TV188_000532"
     CDS             45442..45672
                     /locus_tag="TV188_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEL1533918.1"
                     /translation="MSKKEKKIELQLCDQQVTVNNTKIDGYQLQIGKRVVGEIAELDG
                     KFAVLKDSTVDAFFKTLEQAVENIIENYNLNH"
     gene            45733..45813
                     /locus_tag="TV188_000533"
     tRNA            45733..45813
                     /locus_tag="TV188_000533"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45767..45769,aa:Tyr,seq:gta)
     gene            45852..45923
                     /locus_tag="TV188_000534"
     tRNA            45852..45923
                     /locus_tag="TV188_000534"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45884..45886,aa:Gln,seq:ttg)
     gene            46051..47253
                     /gene="rpsA"
                     /locus_tag="TV188_000535"
     CDS             46051..47253
                     /gene="rpsA"
                     /locus_tag="TV188_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002997242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEL1533919.1"
                     /translation="MNEFEDLLNSVSEVNPGDVVTAEVLTVDNGQANVVIEGTGVEGV
                     LTLRELTNDREADINDYVKAGDTVEVLVLRQVVGKDTDTVTFLVSKKRLEARKAWDKL
                     IGREGEVVTVKGTRAVKGGLSVEFEGLRGFIPASMIDTRFVRNTEKFVGQEFDAKIKE
                     VDAAENRFILSRREVVEEAAKQARDKVFSTLSEGSVVTGTVARLTSFGAFIDLGGVDG
                     LVHVTELSHERNVSPKSVVSVGEEVEVKVLALDEEAGRVSLSLKATTPGPWDGVEQKL
                     AQGDVIEGKVKRLTDFGAFVEVLPGIDGLVHISQISHKRVENPKDVLTVGQEVTVKVL
                     DVNAADERVSLSIKALEERPAQAEGEKEEKRQSRPRHQKREAKRDYELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT        13507 a         8810 c        11132 g        13815 t
ORIGIN      
        1 caatttacca gtcttttaga gcgaagagcg acttgaagaa actgataaat ttatttggtt
       61 ttctgctaaa aatcctgcca aaaaatcttt ggcaggattt ttattttact aagagatatt
      121 taggagtggc tttgtcattt aatgcagatt atgatatagc aggagacata ttgttgaagc
      181 tgtctatgtc acttttggtg gcaggtaggt cttattggaa ttggtgactt atgacattta
      241 tcggtggctg taagcgtttg actttttcac gtttcatagt ggtccgctct ggaatgagtg
      301 ggtatttttt cagaatatga tcaaagatag atgacatgtt ttacagcagg ctatagctgg
      361 tatgatttgt ttaaaaaatc aaggccaatg ataagtgctg ggtgacataa gtcttatggc
      421 tttacttctt gttagcttgt gtcagcaggt gctgagtcaa tcgttgtagg aattatcgta
      481 aacctaacag tagctgctgt tctatttgtt tattttctgg tttctattca aatttctaaa
      541 atgctagggt aacaaatatg aaacaagcaa gtggcgtact gcgaacagct tgataactta
      601 ttgcctgctt aaagagggtg ctgttatgct tggttttatt aggcttatgg catgggatta
      661 aaaggttgct gtagcgccat tgtcattatt ttggtacaat aataggtaaa agactaaatg
      721 tataggaaaa tagaatgaac agtcaagaat taaaaaaacg tcaggagaac attcgtaatt
      781 tctctattat tgcccacatt gatcatggta agtcgactct tgctgaccgg attttggaaa
      841 agacagaaac ggtttcaagt cgtgaaatgc aggcacagct ccttgattca atggacttgg
      901 agcgggagcg tgggattacc atcaagctaa atgcgattga gctgaattat aaggctaaga
      961 atggtcaaga ttatattttt cacttgattg atacaccagg gcatgtggac tttacctatg
     1021 aggtgtcccg gtcactagct gcctgtgagg gtgctgtttt agtggtggat gctgctcagg
     1081 ggattgaggc acagacccta gcaaatgtct atctggcgct tgataatgat ttggaaattc
     1141 ttccagtgat caacaagatc gatttgccag cagctgatcc tgagcgggtt cgtcaggaaa
     1201 ttgaggacgt gattggtcta gatgcttcgg aggctgtact tgcctctgca aagtctggga
     1261 ttggtattga agatatttta gagcaaattg ttgaaaaggt tcccgcaccg tctggtgatg
     1321 ttgatcaacc gctgcaggcc ttgatttttg attcggttta tgatgcttat cgtggggtta
     1381 tcctgcaggt gcgtgttgtc aatggtatgg tcaagccagg tgatacgatc caaatgatgt
     1441 caaatggaaa aacctttgat gtgactgagg tggggatttt tacccctaag gctattggta
     1501 gggattttct tgctactggt gatgttggct atattgcggc ctcaatcaag acagttgctg
     1561 atacgcgtgt cggtgatacg gtcactctgg ctacaaatcc tgcagcagag cccttgcatg
     1621 gctacaagca gatgaatcca atggtgtttg cagggattta cccgattgag tctaacaaat
     1681 acaatgatct tcgtgaggcc ttagaaaagc ttcagcttaa tgacgctagc ttacagtttg
     1741 agcctgaaac ctcgcaagca ttgggctttg gttttcgttg tggctttctt gggctgttgc
     1801 acatggatgt cattcaagag cgtttggagc gtgaattcaa cattgatttg atcatgacag
     1861 ctccgtctgt tgtctatcat gttaatataa ctgatggtga catgcttgag gtctctaacc
     1921 cgtcagaatt tcctgatcca actaaggtag atagtattga ggagccttat gtcaaagccc
     1981 agatcatggt gccgcaggag tttgttggtg ctgttatgga gttggcccag cgtaagcgtg
     2041 gagattttgt gacgatggat tatattgatg acaatcgtgt caatgtgatt taccatattc
     2101 ccttagctga aattgtgttt gacttctttg ataagctgaa atcatcaacg cgaggctatg
     2161 ctagctttga ctatgaaatt gctgaatacc gtcgctcgca gctggtgaaa atggatattt
     2221 tgttgaatgg tgataaggtt gacgctctta gctttattgt tcatagagca tttgcctatg
     2281 agcgcggtaa gctgattgtt gagaaattaa agaaaattat tcctcgtcag caatttgagg
     2341 tgccgattca agcggctatt ggtcaaaaga ttgtggctcg ctctgatatc aaggccttac
     2401 gcaaaaacgt tcttgctaaa tgctatggtg gcgatgtttc ccgtaagcgt aagttgcttg
     2461 aaaagcaaaa ggctggtaag aagcgtatga aggctattgg ctctgttgag gtgccgcagg
     2521 aggccttctt gagcgtccta tcaatggacg atgagagtaa gaaatagtga catgttaagt
     2581 aaggagctgg atcatgcgat ctggctctta tgcttgatgt ctcgataggc tagaaaatag
     2641 ggcttgtgtc atgataggct tgtatgtttg agatggtttg gaacataatg actctatcat
     2701 atctgtagtg gattgacaaa gagccgtaaa ccattgatat ttggatagtt aatttcgagt
     2761 tattctgtag tactctctta aggtctttca tatgagcttt tctaatgttg gtttggttgc
     2821 ttttcatgat aagtcatatg ggattttttt ggtatactga aaaaagccta tagcctctac
     2881 agtggcgtct ccctctacag agatgataga gccagagtga ttgttacgat ctggagatgt
     2941 ggcgctaggc attaatgcag gaggacttaa ccagattgct gttaggcttg aaatcttaag
     3001 ctatattgat tgtcagcttg atttagagaa gtctaagttt atggctcaca aatgctcggt
     3061 ctttttgtta caatagagtt aatcagttat ttttataagg agacagctat ggaatctaag
     3121 gaagagcttc gccagcgtat tggagatttg gcttttgagg tgactcagca tgcagcgacc
     3181 gaaagagcct ttacaggtca gtatgatgat ttttttgaga aggggattta tgttgatgtg
     3241 gtgagcggag aggtgctctt ttcctctttg gataaattca attctggctg cggctggcct
     3301 gcattttcta agccgattca gcatcgtatg gtaaccaatc accatgattc atcacatggc
     3361 atgcggcgtg ttgaggttaa aagccgcgag gctggctccc atttggggca tgtttttaat
     3421 gatggcccta aggaggcagg aggcttacgc tattgcatta actccgccgc gctgaaattt
     3481 atcccctatg atcaaatgga gcaagagggc tacgccgaat ggttagggat ttttgataag
     3541 agctaggaat tgctagcggc caatgaaaag gtagagctct tagccaatgc tagtggctaa
     3601 atcaaagaaa taaaaaggtg gctaaagtac atagaaaaaa gaggtaagca gattggcagg
     3661 tggtcaatct gctttttgtg aggagacttt cagcctgctt tgcgctaaaa agtatgaaac
     3721 caataaacca cctactatgc gggtgtgtgt cggtggttag cttaagtttt ttcagttcgg
     3781 ttttacaagc ttctctaaaa ggactataat agctaatgga aaaggagatt catatgctaa
     3841 catctttaga aaaattaccg ggcgttttac tgtgcttgct gttagcactg cctgcctggt
     3901 atttgggaag cttatttcct attattggag cgccagtttt tgctatttta ttgggaatgc
     3961 tattggcgct tgtctatcag aagcgtgact acactaaatc tggaatcgca ttgacgtcca
     4021 aatatatttt gcagctggct gtggttttct tgggctttgg cttaaacgtg acacaggttt
     4081 tagtggttgg cttgcaatcc ctgccgatta ttgtagtaac gattgtgact gccttgggca
     4141 taagctattt gttcaaaaga tggttaaggc taccagccaa gacagctatc ttagttggtg
     4201 tgggctcgtc tatttgtggt ggctctgcta ttgcagccac agctcctgtc attgatgcgc
     4261 aggacgatga cattgccaag gccatttcgg ttattttttt gtttaatatc ttggcggcct
     4321 tgctatttcc agctttgggt cagatgcttg gcttatcaaa tcatggcttt gctatttttg
     4381 ctggaacagc agtcaatgat acctcatctg taacagctac agcgacagcc tgggacgcta
     4441 ttcaccagtc taatacgcta gatggggcaa ccattgtcaa attaaccaga acgctggcta
     4501 ttattcccat aacacttggc ttatctattt accaaaccaa gagcaggcag gcacatacga
     4561 cagagggttc ctttagcctc agaaaggctt ttccgacctt tattgtcttt ttcttgctag
     4621 cttccttgat aaccaccttt gctgctagct taggtctgcc aatggcaatc tttcatcagc
     4681 ttaagctact ctcaaaattc tttatcgtta tggccatggc agcgatcgga cttaatacca
     4741 atctagtgac cttagtcaaa actggtggta aggccatttt gctgggtggg atttgctggc
     4801 tagcgatcac atcagttagc ttagcaatgc aggcagcttt ggggagctgg taactgatga
     4861 gaatagctgg tgatacgctg ctttatagga aaagcaaagc ccttgctgct cctaaaaaag
     4921 cttgttagag cagctcactt agctgttaag tgtggcttgg tggggtgtaa gtaggctcta
     4981 tcagttagaa aagccatcag aacaaacgct atcattaagc tgaagccggg gaaactcggc
     5041 ttttacgtta tgcagaattg tctacatatt gaataggatt atccatttta aaaacgtttt
     5101 catttgatag aatacaatta tagcttggtt attagggtaa acgagattga acttcttatc
     5161 tggtttagct taagtaaaaa agcagttgga ggaagcatga aacgtaaatt tttaattggt
     5221 agtcatggga gaatggccag tggattgaaa agctctattg acattttggc tggtagaggt
     5281 caggaattac aagtcattga cgcttatatt gatgatagtg attatactga gcaggtattg
     5341 acctttatcg aagatgtagc agctgacgag caggcactga tttttacaga tttattaggt
     5401 ggcagtgtta atcaaaaaat agtaactgcc ctaatggaca gtggcaagga aaatatcttt
     5461 ttgatttcaa atagtaatct tgcagccttg ctatcgttga tgtttttaaa gccagaagaa
     5521 gagctgacaa aagacgagat tgtagcaacg attaacgatt ctcaggtgca gctggtggat
     5581 ctagctccag cgacagccgc agaagatgac ttttttaatt gaggaggaaa aatgaaatga
     5641 ttacacaaat tcgtgttgac gacagattga ttcatggaca ggttgctgtt gtttggacca
     5701 aggagcttaa tgcccctttg cttgtggtgg ctaacgatga ggctgctaaa aatgagatta
     5761 cacaaatgac tctaaaaatg gcagttccta atggcatgaa attattgatt cgctctgttg
     5821 aggactctat caaggttttc aatgatccac gcgcagtgga taagcgtatt tttgtcattg
     5881 tcagctcgat taaggatgct tgccagattg caaagcaggt gaaggactta gaggctgtta
     5941 acgttgcaaa tgtagggcgc tttgacaagt cagacccagc aactaaggtc aaattggctt
     6001 caagcctatt gttaaatccg gctgaattag aagcagcaaa agagctggtt agcctgccta
     6061 acctagatgt tttcaatcag gtactgccat ctaatagcaa ggttagcctg agccagctca
     6121 tcaaataaag aaaggtgtaa tgactatgtt agtaccagca acaatggcag ccttagctgt
     6181 attgatttgt ttcgggggaa attatttaac tggccaaagc atgatggaaa gaccgcttgt
     6241 ggttggtttg gtgacaggat tgctcttagg agatatgaag gtcggtatct tgatgggagc
     6301 gtcactagag gcacttttcc taggaaatgt taacattggt ggtgtcattg cagcagagcc
     6361 tgtaacagca acagctatgg caacgacctt taccatcatt tcacatattg atcaaaaagc
     6421 agctatgacg ctagctgttc cgattggcat gctagcagcc tttgtggtca tgtttttgaa
     6481 aaatgttttt atgaatatct ttgcgccaat ggttgataag gcagcagcgg caaaccatca
     6541 gggcaagctt gtcatgctgc actatggcac atggattgtc tattatttga ttattgcctc
     6601 tatttccttt atcggtatcc tagttggaag cggacctgtt aacgcctttg ttgagcatat
     6661 tccacaaaat ctgatgaatg ggctaagtgc agctggtggt cttcttccag cagtcggatt
     6721 tgccatgctg atgaagctct tatggacaaa taagctagca gttttcttcc tattaggctt
     6781 tgtgttgaca gcttatttga agctaccagc agtagctgtg gctgcacttg gtgcagttat
     6841 ctgtgtgatc agctcgcagc gtgatttaga gttagatgct attactaagg gagctatcag
     6901 taaccaaagc agctttgact ctaaagaatc agaagaggag gacttctttg catgagatct
     6961 caagacaatt taactaaaga agaaagaaaa atgctacgct ctgttttctg gcgttcatgg
     7021 accatgaatg ctagtcgtac aggagctacg caataccacg ctgttggggt tatctatacc
     7081 ttgttgcctg ttatcaatct cttttataag acagataagg ataaggcaga cgctcttgtt
     7141 cgtcacacca cttggtttaa tgcgaccatg catattaata actttatcat gggcttggtt
     7201 gcctcaatgg aaaagaaaaa cagtgaggat ccaacctttg acgctagtgc tattacagcg
     7261 gtcaaggctt ccttgatggg acctatttct ggtgttggag attccttttt ctggggtatt
     7321 ttgagggtca ttgcagctgg tattgggatt tcacttgcta gcacaggctc agcgatggga
     7381 gcagtagtct ttttacttct ctataatatt cctgctttta tcattcatta ttatagcctt
     7441 tatggtggct attctgttgg tgctggcttt attaaaaagc tttatgagtc tggtggtatt
     7501 aagattgtga ccaagacctc aagcatgctt gggtcaatga tggttggctc catgacagct
     7561 tcaaatgtga agtttaagac cattttaaca gttgctgcaa agggagccaa ggaagcagcc
     7621 tctatccaaa attatttgga tcagctcttt attggaattg tccctctttt agtaaccatg
     7681 accgcctttt ggcttttgcg taagaaggtg aacattaact ggattatgtt tggcattatg
     7741 ctattgggta ttgttcttgg tcttttaggt atttgctaat aatctcctag catcaaggat
     7801 aggtaaggca gggacttctt gctttgctta tccttttttg tagtgagggc tgctgaaata
     7861 gccacctgct tgcttaaatg gcttatggat ttgttagata gattaagatt ttcttagctt
     7921 tgagaaatga tttggtataa tagaaggaaa taagggaaaa ggctgcctat ggaagaaaga
     7981 tttaaaaagc gattgcagga tgatatttca catcattttt cacaccaatc attgattttg
     8041 tccattttac tgattggact ctttctcatt ttttcattgg cacctcagca aattgggctg
     8101 tatcaagatt tgaaggctgt tgaacatagc tatcaccagc tgattcggca aaataaggcg
     8161 cttttaacgg agctcaatca gcatattctg accaaatttg tgaatcatca gctgagctct
     8221 tctgacctta gcaaacaata ttatcaccta agaaaccgct cacaaagcca atcagagctg
     8281 ctggtttttg atgctaacag tcacatgctg tttgctagta atcagcatct gggaaatttt
     8341 tttcgcaatg ctgtctatat gacagaagtc ttaaaaaaag caaggcaaag gagtagcttc
     8401 ttgaggatca gtatggataa tgaggagggg cattatttac tgctgataaa gcctattaag
     8461 atagatcatc aggttaaggg ctattcgctt cttgtgatga atggtaagga ttttcttcag
     8521 ctatcacatc agattgcttc agattttgtg attgcagatc agtttgacaa tagctttgcc
     8581 tttaccaatc ggacctttat gacctcaagt ctgaataagc ttgacagtca ttttcttaag
     8641 ggctatttta tctttcacga gcatcgtgcc tttatcctaa gaaaggtcgc tcttagtcct
     8701 tctatcactc tttacagcta ccgccctttg attccagttt ctattgcact cttgttttca
     8761 ttgatgtcct ctgtcatgat ttatgctatt ttgtattgga agtctaaggc tctggcgacg
     8821 cagattgctt ctagcaattc agcagcgatc aatcagatga ttcttgatat gcaggccatc
     8881 tcaaggcagg aaaaaaatgc cattgacctg caaagtcaag atgaatttca atacctgtcg
     8941 gttcagatca atcagatgat tagccgattg caggcacttc atcagaagac cctagcctta
     9001 gaaaagcaaa atgtgagttt tgaaaaacgc atgctggaag cccaatttaa ccctcatttt
     9061 ctctataata cacttgaaac aattttgatt acaagtcatt atgacagtga cctcacagaa
     9121 aaaattgtcc ttcagctaac caggctgctt cgctatagct tagacgaatc acaggaggct
     9181 gtgtgtctgg gagaggattt ggctgtctta gaatcctatc tgttgattag ccagattagg
     9241 tttgaagagc tgcgctacac gatagctgtt gaaccagccc tagagaccct aagggttccc
     9301 aaattatttt tattgccatt gattgaaaat gcgatcaaat atggtctgcg ctatcgccat
     9361 gaccttgtga ttgagatcag cgtgagacag cttgctgatg gaatttactt tactgtagca
     9421 gataacggtc ctggaattag tcaaaaaagg caggccgata ttaaagagct cttgcattca
     9481 gaggattcac atcatggctt ggtcaattct tatcgtcgac tcaagcatca atttataaaa
     9541 gttgaattga tcttttgtca aagagatgag cgctttttac taacctatat ggttaaggag
     9601 taacagatgt ataagctact aattgttgaa gatgagcata ttattcgcaa atggcttcgt
     9661 tatgcgattg attatcatgc gctcaatatc cttgttatcg gagaagctaa ggacggtcag
     9721 cagggggcta agctgattgc agaggctaag ccagatattg ttttgacaga cattaacatg
     9781 ccgattatga ctgcctttga gatgtttgag gccacaaaag agcagtccta tgctaaaatc
     9841 attttgtctg gctatgctga tttcgctaat gcaaagtctg ctatccatta tggtgtgctt
     9901 gagtttttga ccaagccctt ggaaaggcag gccttacatg attgcttgct aactattatc
     9961 caaaagctgc aacagcagtc tcaagagcag gagctaagcc agcagcagga ttacctcaaa
    10021 ctgccacagc ctaatgacca attgcctgat gttgtccaag aaatgctcag ctggatccat
    10081 gagcattacc aggataaaat catgattggt cagttggctc acgatctggg ctatagcgaa
    10141 agtcacctct atcatttagc taaaaaatac ctgaaaatga cttttagtga ctatatcaac
    10201 caataccgcc tgaatcgagc aattcaattg ctgattgctg agccggatgt gatggtttat
    10261 cagcttgcag aggctgttgg catttatgac taccgctatt ttgatcgtgt gttcaaaaaa
    10321 tatttaggac aaacggtcaa ggatttcaga gaaacggtat tacaccagag atcagatagg
    10381 agttcattgt gacaagaaaa aagctgctat tagcaatggc aatagtgata ctaggtgtga
    10441 ttggctctgg cttgtatgct atctggaggc atcaagcagg accagctccc agcaaaccaa
    10501 gagaattggt tgttttgaca cccaacagtc aaaatatcct aacaggtacg atcccagcct
    10561 ttgaagaaaa atacggcatt aaaatccgtc tgattcaagg aggcacaggc cagctcattg
    10621 atcgcttgca aaaggacaag gaccagctcc atgcagacat cttttttggg gggaattaca
    10681 cacaatttga gagtcataag gagctatttg agccttacct ttcaaagcat attggctttg
    10741 tattgcctga ttacctgctg caaagcgagg tcgcaacccc ctatacgctt aatggaagtg
    10801 ttctcattgt gaataatgaa ttggcaaagg acatggttat taccagctat gaggatttgc
    10861 taaagccaga gctaaaggga aagattgctt ttgcagaccc caacacctcc tctagtgcct
    10921 tttctcagct gaccaatatt ctcttagcca aggggggcta cactaacccc aaggcttgga
    10981 gctatatcaa gcagttgatt catagcatga attcaatcaa atctgctagc tcatcagatg
    11041 tttatcagtc agtagcagaa ggaaagatga ccgtcggtct tacctatgag gacccctgtg
    11101 ttaacctttt aaagagtggt gccaacgttt ctattgtgta tccaaaggag ggaacggttt
    11161 ttttaccctc agcagttgcc attgttaagc aatctaaggc caaggctgat gccaaattgt
    11221 ttattaatta tatgttgtct ttagatgtgc agcgggcctt tggtcaatca accagtaata
    11281 ggccaattcg aaaggacgct aaggccagtc aagacatgaa gcctttagat gacattatca
    11341 cgctaaagga agactatgat tatatcacaa gacataaaaa ggatatttta gaacgataca
    11401 atcaattgag aaagaccact gactaaatgg ctttgttata tgaaacagtt catgctgtgc
    11461 tgcacctgaa tcgttagctg ctttgtctag ctttttgagg tcaatctctg cttgggctgt
    11521 tttttatgtt accataaccc actgcatttg tttagaaagt caagcgagat cttaatagcc
    11581 agttataata ggtctttgag agggagtctg agcttgcttg aggtggcaag aagatctgtt
    11641 ttgacgtcaa atggctgaat ttttggtaaa atgatagcat gaatgaactg ataaaacaca
    11701 agctagagct tttgccagat agtcctggct gttatttgca taaggataag gctggcacta
    11761 ttatttatgt tggcaaggcc aaaaatctga gaaatcgcgt acgctcttat tttcgaggaa
    11821 gccatgatac caagacagag ctgttagttt ctgaaatagc tgattttgag tttattgtca
    11881 caggatcaaa tacagaagca ctcttattgg aaatcaattt gattcaagag aacatgccca
    11941 agtacaatat caagctaaag gacgacaagt cttatccctt tatcaagatc actaacgagc
    12001 catttccaag actattaatc acacgtcaga ttaaaaaaaa tgacggcctg tattttggtc
    12061 cctacccaga tgcttacact gccactgagg ttaaaaagct gctagaccgt atttttccct
    12121 ttaaaaaatg caaaaaccct gttaacaagg tctgctttta ctatcattta gggcaatgtc
    12181 aggctcacac gatttgccat acagacaagg cttattggga cagcttggtt gctgatgtca
    12241 agcagttttt aaacggtaag gacgacaaga tcattgatga tttgcgctcc aagatgcttg
    12301 aagcttcgca caatcaagaa tttgaacggg cagctgaata tcgtgatttg atttcaggta
    12361 ttgccaccat gcgaaccaag caaagggtga tgagtaagga cttgcaggat agggatattt
    12421 ttggctattt tgttgataag ggctggatgt gtgtgcaggt cttttttgtc cgtcagggta
    12481 agctcattca gcgagatgtg aatatgtttc cttattacaa cgaagctgaa gaggattttt
    12541 tgacctatgt cgggcaattt tatagcgacc aacggcattt gatccctaag gaggtcttta
    12601 ttccagagac gattgatgag accttggttg cagccattgt tccagcaagg attgtcaagc
    12661 cgcagcgagg ggaaaaaaag cagctggtcg ccttagcaac taagaatgct cgggttagcc
    12721 ttcagcaaaa atttgatttg ctggaaaagg atttaagaaa aacaagtggt gctattgagc
    12781 atcttggtca gctgttaggc attgaaaagc ctgttcgtat tgaggccttt gacaattcaa
    12841 acattcaggg cacaagtccg gtagctgcga tggtggtttt tgtcgatggg aagcccagca
    12901 agaaggacta tcgcaaattt aaaatcaaaa cagtgattgg tccagatgat tatgcgagca
    12961 tgagagaggt gatttatcgt cgttatagcc gcgtgaagca tgaagggcta caggcacctg
    13021 atttgattat tgttgatggt gggcagggtc aggtcaaggc tgctcgtgat gtgattgagc
    13081 accagctagg ccttagcatt ccagtagctg gtctgcaaaa aaatgacaag caccagaccc
    13141 atgaattgct ttttggtaac cccttggcag tggttgagct gccgagaaat tcagaagagt
    13201 tttttctgct gcatcgtata caagatgagg ttcatcgctt tgccattacc tttcacaggc
    13261 aggtcaggag taaaaatgcc ttttcatcaa agctagatca cattgcaggc ttagggccaa
    13321 aacgcaaaca gctactactc aagcgattta aaagcatgac tgctcttgaa caggctagtc
    13381 ttgaagaaat tcagcagcta gggattccaa aaacagtcgc tgaggcactg tttgatcacc
    13441 ttacctcaaa aagtgaggtc tgaattggcc ttgtcaggag ctcaagcagt ctgaattttc
    13501 ttgacaaaag tgaaaaaata gctgaaacca gtttcaaaaa atgatagaat gatactacaa
    13561 cataaaagaa ttagatagga agcatttgca gtgaaatttc tcgaattaaa caaaaaacgc
    13621 catgctatta aacggtttaa cgataagccc gttgattata atgacttgcg aacagctatt
    13681 gaggttgcca ctctggcacc aagtgctaac aatattcagc cttggaaatt tgtcattgtt
    13741 gaggaaaaaa aggcagagct ggcaaaggat ctgccgttgg ctaataagac tcaggtagag
    13801 caggctcagt atgttattgc cctgttttct gataccgacc tcattcagcg ctctcgtaag
    13861 attgcccgca ttggggtcaa gtccttgcct gataacttga ttggttatta catggagacc
    13921 ctgccgccac gttttgctac ctttactgag acccaaaaag gcgaatatct ggccattaat
    13981 gctggcttgg tggcgatgaa tttggtcctt gccttaacgg atcagaaaat ggcctcaaat
    14041 attattttag gctttaataa aaagctaact aatgagattt tagatattga tccacgcttt
    14101 cgtcctgaat tattgataac tgtggggtat agcgatgaca agccagagcc tagctatcgc
    14161 ctaccagtag acgaaatcat tgaaagacgc taagatacac aactactcgt ccagctagcc
    14221 tataagtttt tggatttagg aggatagcga ggcaacacat aaaggagaaa aagatgacaa
    14281 caattgattt taaagcagag gttgataagc gcaaggaagc tatgctagag gatctatcaa
    14341 acctattaag cattaattcc gagcgagacg atgctaaggc agatgccaag cacccatttg
    14401 gtcctggtcc ggttaaggcc ttggagttct ttcttgccat ggcagagcgt gatggttacc
    14461 aaacgcgtaa tattgataac tatgctggtg attttgaatt tggtcaggga gatgaggttt
    14521 tagggatttt tgcccattta gacgtggtac ctgctggtag tggctgggag acagaccctt
    14581 ataagccggt gattaaggat aatcgtatct atgcgcgtgg ttcatctgat gataaggggc
    14641 caaccatggc ttgctattat gccctgaaaa tcatcaagga attaggcttg ccagtttcta
    14701 aaagggttcg cttcattgtt gggactgatg aggagtcagg ctggggtgat atggactatt
    14761 attttgctca caatggcttg aagaaccctg attttggttt ttcaccagat gctgaatttc
    14821 ccattatcaa tggtgagaaa ggaaacatta cagaatacct tcattttgtt ggtcaaaatg
    14881 ctggagcttt tgtccttcat cgcttccaag gcggtttacg tgaaaatatg gttcctgaat
    14941 cagcgacagc tctgatcagc tcaccgcatg agcttaatgt tatcgaagct tctttggagc
    15001 aattcttatc tgagcacgca gtgacaggat ctgtcaaaga ggctgatggg ctattggaag
    15061 tgaccattat tgggaaatct gctcatggct ctacaccaga ggctggtgtt aacggtgcaa
    15121 ccctgctggc taaattctta aatcaattta gctttgatgg cgcagccaag gcttatttgc
    15181 atattgcagg tgaggtgctt catgaggatt tcacagcaga aaagcttggc ttggcttata
    15241 cagatgacaa aatgggtgcc cttagcatga atgcaggtgt ctttagcttt gctaaggatt
    15301 cagatgacaa taccattgcc ttgaatttcc gttatccaaa gggaaccaat gcagcagtgc
    15361 taaaggcagg gcttgagcaa ttaccaggct tgactaaggt taccttatct gagcatgaac
    15421 acacccctca ctatgtgcca atggacgatg agctggtctc aaccctccta tccgtctatg
    15481 aaaagcaaac aggactcaag ggctacgagc aggttatcgg tggtggcacc tttggacgct
    15541 tgcttgagcg tggtgttgcc tttggtgcga tgttcccagg tgatgaaaac acaatgcatc
    15601 aggccaatga atacatgcca ttagacaata tttaccgatc agctgccatt tacgccgaag
    15661 ctatttatga attgatcaaa taagagattg aacaagctct ctgtctaaga tgagccttgc
    15721 taatattaac gaataaaagc cttatgaagt tagtcgttta atgagacttc ataaggcttt
    15781 ttgtttggcg tcaagccatt atttacaaag agaaatgcca cagtggatca tcttttgaaa
    15841 agtccttgta aaaacagacg taaaactagt tttagaggag acattgatag gcagtcatgc
    15901 ttatcaagag atcttgtcta gcagttatgg caaaaagatc agtgaactat tattttccaa
    15961 ggcagaactg actgaacaat tgagtaatta attcatcagg tgcggcatcg cctgtgattt
    16021 ctcctaggat ttcccaagct ctggtcaaat caatctgtaa gagatcaacc ggcattccta
    16081 aagcaagtcc ttcattgaca gcctctaagc tttgtactgc ctgctcaatc aaggaaatat
    16141 gacgagcatt ggataggtaa gtcgcatctt gctctattag cccagtatga tcaaagaaaa
    16201 tctgattgat ccggtcttcg atcaggtcaa tgttttggtt ttgcaaaact gatattggga
    16261 tcgcctcttc tggaagctgg tctttttcaa tgacctgctc cagatcggtt ttattgagga
    16321 gaataatgcg attgctatcc tgactaaggg ctagcagagc cttgtcctgt tcggtcagct
    16381 tttccgaagc attgagaact aaaaggacca gatcagcctc ctgtagggct tttttagacc
    16441 gctcaacacc aatttgctct actaaatcat ctgtttctct aattccagca gtatcaacta
    16501 gctttagagg aattcccttg atattgacat attcttcaat gacatcacga gttgttcctg
    16561 caatatcagt gacaatggcc ttatcctcac gtaacaaggt attgagcaga ctagactttc
    16621 ctacattcgg tcggccgata atagctgttg acaagccctc acgtaggatc ttcccgcgct
    16681 tggcagtacg taggagctgc tctaaaagtg tttgaaattc tcgcgttttg tcacgcaaaa
    16741 gagcagtggt catttcttcg acatcatcat attcggggta gtcgatatta acctcaacct
    16801 gggctaaggt atttaggatt tcttgacgtg tgtcgctgat gagctgtgat agggagccgt
    16861 ctagctgctt gatagcaata gacatggcct tatcagtctt tgcacgaatc agatccatga
    16921 ctgcctcagc ctgtgttaaa tcaatacggc catttaaaaa agcacgcttt gtaaattcgc
    16981 cgggctctgc cattcgagct ccctgtttaa tgaggagctg taaaatgtca tttgtcaccg
    17041 caataccgcc atgggtattg atttcaatca cgtcctctct ggtaaaggtt tttggcgcca
    17101 gcatgactga taccatgacc tcatcaatca cttcacctgt gcttggcttg ataatatgac
    17161 catagttaag ggtatgtgag gcgactgttg ttagatcttt tcctttaaag atcgatttag
    17221 caatgtccag agccttggta ccagacaagc gaacaatgcc aatagctcct tcacctaacg
    17281 gagttgaaat ggctgcaatt gtatcaaatt ctttagttat actcatgcct tctattgtag
    17341 aacaagtcag catagaaagc aaggtattgc attagctgct cgttgtcgtc attcttgtct
    17401 agtggcaaag cctcaaaagc agttgtaaac agctaaagct atgattaaaa agccttgtat
    17461 ggtaagtaca ggataaagcc aaaaagctga tgagttttag ataaacatac aggctcgaaa
    17521 agccctatta aaccgacagc aacaatcctc acacagtata gttgacttaa ctacctgatg
    17581 tcatttctgg ctgtttttat aatgacaatg gcaatatcgg ttattttgac tatgctgggt
    17641 gcttgtatcc tagtggactg actgacaatc agggcttctt tttcaaccac gaaaacatta
    17701 aaaaagtctg gtttggaggc tatattgacg atagtgaaag agaagctcaa gactttttta
    17761 aaaaagaggc aggctatatt aaatatccta aacttagtat agataatagc actagatagc
    17821 attaatttaa gtatataacg ttatgattat ggttggatta gttcattata cactagcaat
    17881 aaggtagatt attttgttat aataaaatat atacaattat tagagagtta gaaagagtta
    17941 tatggtagta ttacaaaata atagtagcac agctagtgag cgagcgacag ctttggcaag
    18001 aggagtccag gccctctcta gtgctggtgc ggtgagcaaa gatatgaaga cgaccgttac
    18061 tggaaatcgt agtgatgcca gctctgccat tgatttatcg cacaacgttt cagcgcaggt
    18121 agttgggatc atcgcttcta tgtcgcaaca cattcagagt gtctctgcct cttttcaagc
    18181 gatggatctt cagcttggaa aagagttagg gcgtttagaa aacaggcgga ggtttagtct
    18241 caatgaccca aaatgagctc atgtaccaga aggagagatt ggataaacgc ttggaaacca
    18301 tagcccaaga gcttaagcgt aatgaacagc gctttgaaga ctatgaggaa ctatctaacc
    18361 tagcggcaca actgttaaca gcagctgcaa ccacctttcg ttcatcatca gatagtcatc
    18421 tctttgaagg ggctttggca gaagaatgtt atttgaaaag gaaaacacaa gcgtccttgg
    18481 aacaaagtca tgaggagctc ttaggagagc agcgtcgttt gtaccaagaa gaggaagccc
    18541 tcacccgaca attaaagcta gtcaaaggaa aggagagagc taatgagcat tgacatgtat
    18601 ctggggtcat cggaccagca agctagtagc gttggtaagg tcttgcagca gcggataaca
    18661 gcttataagt ctttgcaaag agctttggag caattggtgt cttctagtcc tgacttatca
    18721 gggcatacct atgcttctgc taaaaggtac agcgagcagg tattgatccc tttgatgagg
    18781 ggctgtatcc tgctagatga agccatcaag gaagcctgtg cagcatttcc taatgactac
    18841 cgtcgtcagg ttgatagtgt ggatttgaag gagagtgagc tggtggatca gatcagccgc
    18901 tcagaccgca tcataggtcg ttacgttgag ttgattgatc tggagtatcg gcaggagctg
    18961 ccgaattact cttatattac taatctcaag agcggagcga gtaaccagcg tcaagtcaag
    19021 agaaaattag aagagaagct ccttaagctg cgagagtttg atagcaattc ccgtcacctc
    19081 ttttcgtcta tcgcagcctt agccgaggca gtcaatatag gtatcagaca aaccaagacc
    19141 tcttggaatg ggacaagtca gacgttcact cttcccaggg ctcttgactt agagtggacc
    19201 aaggtagtag aaaagaggtg gacgcaaagg gaggaaaaag cctcgaagct gaagctacag
    19261 caggcagcag aaaaactttc gagagaaacc gggattaagt acgaagatgc ctatcgtttt
    19321 gtgatggacg gtgttctgtc agatgaaaat aagaacaaaa tcaagagtgt aaagaaacta
    19381 gttaagtata caaagggtgg gctgtatatc gtttcctcag gaaggtatta ttggaaacat
    19441 tcaggtaaac attattggaa aaatacacca aacaaaacat ggaatatttg gaaagcatct
    19501 aaaaacgatc ccaattttga caaaggaggg atcaaaggta aacatttttc taaaaaagga
    19561 gcccgttaca cagacttacc tggtatcaag caattgaaga agagtgaaac agtacaatcc
    19621 ctcatttcaa aaatttcaaa agataatcaa gggaagctca ccaaagttgg taaagggtta
    19681 aagaaagttg ataaagagct aagcaacata tcgtcaaaac tcaagtcata tgagcatgga
    19741 cgcctaaata gagacttgaa aatgatgaag gagaataacc tgggtaaaag tctcggtaag
    19801 tttgggaaag ttggaaaagc tgcaagcaag gtgctcaagt ttgcaggaaa aggtctcaaa
    19861 gttgcgggtt gggtaggtgc tgctataaat gttaaggact cggttgaaac ttacaagaaa
    19921 aaaggctata gcaatgagca aactgctgct ttaacagccc gtaaggtagc tgttgatact
    19981 gcaacaactg ttgtcggaag caatattggg cgtgtaacag gtgcagttat tggtcaagca
    20041 gttataccta ttccaggtgt aggtgctgct atcggttctg ttgcaggaag tattttagga
    20101 gctatggcag gtagttggat tggtagtaca attaatgaca atttagataa gaacgtaaaa
    20161 cctaaacaat caggaaggag tttagcatgg taatgttaat gagaacactg ttatttccag
    20221 ttgataacgg acttgattca ggattgactg gtgatggtta tgcagctgag tatgatttgt
    20281 ggactggaaa ggtcacgtgg cgacaacttg gtgatggaaa aataaaaagg caacaaaagg
    20341 tagcagctat aattaatctc attgcagctg caatatctcc acttgtcatc atgtctatca
    20401 tttttacggc aaaaagtctg aagctttttg atgtagatac tagtacaaca atttatcgat
    20461 atgctcctct gatggtaggc ttggtctttt tcttctcgtt tgaattattg atgctggcta
    20521 ttagacgtct gtatccatta gccaaagagg agccaagttt aaagcgtcaa catgggtatt
    20581 ttaagaccat gtatgacaat actatacgtg agaatgatgg tgtttttaat aatttatcag
    20641 taccttttat agggctttat gtagctttct tgattgcctt ttcggttatt ccaatttttt
    20701 actctcaata tctgcagcaa aattcttttt ggtcctattt aggaaattta gtaggaagta
    20761 gcattcttat ttccttagtc cccaattttt tatggaatgt cttagtgaaa caattgattt
    20821 acatcaagct tattcgcaaa acgaaagaaa aaatcttaaa gaatgaaacc taaacaatca
    20881 ggaaggagtt tagcatggta atgttaatga gaaccttgtt atttcccata gataatggta
    20941 tggataataa cttaattgga gacggcttat cagctgagta tgacctatgg actggaaaag
    21001 ttacgtggcg tcagcccagt gatgataaga ttagaaccca acaaaaggta gcatttgtac
    21061 ttaatcttat agctggtagt ttatctccat tagctatatt tttatttgtt attattgtta
    21121 gacgcttagg cgtttttagt ggcgatacta attcaatgat tttcaagtgg gcaccgctaa
    21181 tagttggatt tatccttttt atatcgtttg aattattgat gttggcgctt agaagtagat
    21241 atacgatatt agagaaagag cccgatttag atcgtcaact atactattat cgtacaatgt
    21301 atgataatac tatacatgac aattcaggtg tttttaacaa tttatcagta ccttatgtag
    21361 gtctatacat tactttattt ctaatttttt taatcattcc actttgttat catttttact
    21421 tgcacccatc ttcatttggg gattatctcg ctgcattatc tgtaacaagt ttgttgattt
    21481 ccttatttcc caatttttta tggaatggtg tcttgaagca cgttatatat gtcaaactta
    21541 ttcgccaaac aaaagaaaga attttaaaga atgaaaccta aacaatcagg aaggagctta
    21601 gcatggtaat gttaatgaga acgctgttat tcccagttga taatggcatg ggaacgggct
    21661 tgaccggtga tggttatgcg gctgagtatg atctatggac tggaaaggtc acgtggcgac
    21721 aagccaccaa acaaacaatt gaaaagcaac aagcactaac gtctaacctt ttgattattg
    21781 cctcatgctt atcaccagtt actgttgcag gaatgatact gttgagtaga agtttcccta
    21841 ttttcgagga agacttatca gagaaaattg atacttatgc tccaattatt cttggtgttg
    21901 tgttatttct tgcttttgag acgttaatgc ttgctatcag aggtcgtgat ccattagcgg
    21961 agaaggaacc agatttaaag cggcagcatg actattttga aaagatgttt gattttgcta
    22021 ttcgtagaaa tttgtcgtca gataatctaa aaactcctta tatagctact tattttgctt
    22081 ttggtatttc tttactctgt attccattta gctattatgt ttatctgaat ccggagcaat
    22141 tccctaattt ggattatggt catttatcaa tcctgcttgt aacaagtatt cttatttccc
    22201 tagttcccaa ctttttatgg aatgttctat taaagcacat tatctatatc aagcttattc
    22261 gcaaaacgaa aggacaataa aacattatga acaaaccaga acacatttta ccgattggta
    22321 ctatagtgct gacggagaca ggagaaattc ctttgatgat tgtgagtcgt gcctctcttt
    22381 ttgatgataa tggagaaatc ggctattttg attatgctgc agttccttat ccagaaggca
    22441 taggaaatga taatgagtac cttttcttca accatgagga tattgctgat gtcatctatt
    22501 ttgggtatgt caattccaat gaacagcttt ttgcagaagc ctacgatgat ttggtgaaaa
    22561 catcaggtta tcgtaaatta agcttagatc accatcaata gaaaaaggac atgaagatta
    22621 tctagaaaaa gaaaagaact aatgagcatt gacatgtatc tggggtcatc gaaccagcag
    22681 gctaatgatg tatggccaat attttgagag gatcggcctg ctcctctttt ttgtatgttc
    22741 aaagctataa aaagcttact ttttgaggta taaagcttcg acaatcaaga gtatttgctc
    22801 tggtggcttt aatgatcttg cttatagctt ctggtcagat tgttttagcc tgcttgtgct
    22861 gtctgatcca gatttgactg aggctttgat gacagtcgtg aaggcgggtt taagaatggc
    22921 atgtctaatg tcaatttaca atagagaagg aaaattgatc aaacagtgtg agatattatt
    22981 aacaagtttg cgctttcatg gtataataaa gtgctaggaa gcattttatt ataagataag
    23041 ggggaatcat ggaagcactg aaaaagattg ccggtgtgac tgctgcgcaa tatgtaacag
    23101 atggaatgac cattggatta ggaacaggat caacagctta ttactttgtt gaagaaattg
    23161 gtcgtcgcat caaggaagag ggactacagg ttgttggtgt gacaacctca agtgtaacaa
    23221 ccaagcaagc agagggccta ggtattccct taacatcaat tgatgatatt gactgcattg
    23281 acctgactgt tgatggtgct gatgaggtgg ataaggcctt taacggtatt aagggtggtg
    23341 gagcagctct attgatggag aaaattgttg caacaccaac caaggaatac atctgggttg
    23401 ttgatgaatc aaagctggtg gatcatttag gtgctttcaa gctccctgtt gaggtcgttc
    23461 aatacggtgc tgataggcta tttcgagtct ttgaaagggc tggctataag ccctcttttc
    23521 gcatgaaggg ggataagcgt ctcataacgg atatgcagaa ctttatcatt gatcttaacc
    23581 ttggctgtat cgaaaatcct tgtgagtttg ggcgtctgct ggatcaaact gttggtgttg
    23641 tcgagcatgg ccttttcaat ggtatggttg ataaggtcat tgttgctggt caggctggtg
    23701 taacggtcct tgaagctaat cagtcaacct aattcctagc tcaatcatgt tttacattat
    23761 tttataggtt ttggggagcc aaccgtaacc tcccctagat tggagactta tgtcaaaatt
    23821 taatcgtatt cacttagtcg ttctagattc tgttggtatt ggtgcagcac cagatgccga
    23881 caaattcttt aatgctggtg tagctgatac agattctgac accctcggtc atatttcaga
    23941 gacagctggt ctggctgttc caaatatggc aaaaattgga cttggtcata ttcctcgtcc
    24001 tgtcccccta aagacagttc cagctgaggc tgatcctact ggctatgtca ccaaattaga
    24061 agaggtatct cttggtaagg ataccatgac aggtcactgg gaaattatgg gcttaaacat
    24121 tactgagcca tttgatacct tctgggatgg ctttccagag gagattatcc aaaaaatcga
    24181 agctttttca ggccgtaagg tcattcgtga agccaataag ccttactcag ggacaaaggt
    24241 gattgatgat tttggtcccc gtcaaatgga aactggtgag ctgattgttt atacctctgc
    24301 cgaccctgta ttgcaaattg cagcacatga ggaggtgatt cctgttgagg agctttaccg
    24361 gatttgtgag tatgcgcgtt ccattaccct tgagcgtcct gctcttttag gtcgtattat
    24421 tgcccgtccg tatataggag agccaggcag cttcactcgc acagctaatc gtcgtgatta
    24481 tgcagtctca ccgttccaag acactgtctt aaataagctg gctgacgctg ggatttctac
    24541 ttatgctgtt gggaaaatca atgacatctt taatggctca gggattacca acgatatggg
    24601 gcacaataag tctaacagtc atgggattga taccctgatc aaaagcttgc agttgccagc
    24661 atttacaaaa ggtctttctt ttactaactt ggttgatttt gatgctagct ttggtcaccg
    24721 tcgtgatcca gagggctatc gtgactgttt gcatgaattt gatcgtcgcc tgccagagat
    24781 cattgccaac atgaaggacg atgatctgct cttgattaca gctgatcatg gcaatgaccc
    24841 aacctatgct ggaactgacc acacacgtga gtatattcca ttgcttgctt actcagcctc
    24901 ctgcactgga gcaggtgtga ttccacaggg acattttgct gatatttcag cgactattgc
    24961 cgaaaacttc ggtgtggaca ctgctatgat tggaacatca ttcttagctg acttggtata
    25021 ggagtaagca aatatcattt gataggccaa ggagcttggc gtatcaaatt gaaaaccagc
    25081 gctgtggtta ggtctattaa taggcttgtg gcaggttgtc tagttctgat gatcggtgtg
    25141 atattagttg atttattgga ctttgctaca gcaaaaagct caagagaagt atgctttata
    25201 gtaaaaaata aataagataa agggagaaat aagatgacat tacttgaaaa aattcgtgaa
    25261 acacaggctt tcctagaaag caagggcatt gataagcctg aatttggtct cattttaggc
    25321 tctggtctag gtgagcttgc caatgaggtt gagcaggcga ttgtgattga ttatgctgat
    25381 attccaaact ggggcaaatc aacagttgtt ggtcatgctg gaaaattagt ttatggtgag
    25441 ctggctggtc gtaaagtatt ggcacttcaa gggcgctttc atttctatga aggtaatcca
    25501 atggaggttg tgaccttccc ggtacgtgtg atgaaggctc tgggctgcca tagcttgctg
    25561 gtgacaaatg cagcaggcgg tatcggctat ggtcctggga cgcttatgct aatcaatgac
    25621 catattaata tgacaggaac aaacccgctc attggtgaaa acctagatga atttggccca
    25681 cgcttcccag atatgtctga tgcctataca gcagcttatc gtgagacagc tcgctcagta
    25741 gcagaaaaac taggcttaga cctgcaagag ggtgtttacc ttggctgttc aggaccaacc
    25801 tatgaaacac cagctgagat tcgtgccttt aaggttatgg gagcagatgc tgttggtatg
    25861 tcaactgttc cagaggttat tatcgctgcc cactcaggct tgaaggtgct tggaatttca
    25921 gcgattacaa actttgcagc gggcttccaa tcagagctta accatgaaga ggttgtagag
    25981 gtaactgagc gtatcaagga aaactttaaa ggcttggtta aggctatttt ggcagagctt
    26041 taaggcttgc tcttagacta gcagtaacca tgagcgactg ctagtacttt gatcgataag
    26101 acgaggaaaa ataaggattg ggacattaga gtgatgactg atatggaaca tacgataagt
    26161 attcttttag aagtttatgc ttatagtcat gcctacaaaa ttgcaagaac tctgcctgat
    26221 ttttccccca aggtacttta tttgcttgag cttttaaagg aaagaagaga gcttaacgtt
    26281 gcttatgcct ttcaacatag ggcggaaaat aggcttattg aggatagaca tcaggttaag
    26341 cttttgttaa atgaagctca agaggaggag cagactgcaa attacctgct tgatttggca
    26401 gctaaggtca aaaacggtga gattattgat tttgtaaggt cagtatcgcc tgtcttgtat
    26461 cgtctctttt tgcggctgct tgagcaggct gtcccagatg ttcaaagcta tattattgat
    26521 accaagaatg atcaatatga cacttggaat tttaaggcga tggaaaaagc cgataatgac
    26581 ctctttagga gctatctggc acaaagacag ccacgtcatg tgacgacacg cagcttggct
    26641 gatttacttg ttttatcaga gcttccagct gatattaaaa gactagtggt agtcttaagg
    26701 cagtttgaaa aatcagtccg caatccccta gcacatttga tcaaaccctt tgatgaggag
    26761 gagctatatc ggacaactca tttttcctct caagcctttc tagatggttt gattcgctta
    26821 gcagtttttt ctggtgttaa ctatatcaaa gagcccttct attttgatgt cgttaatgct
    26881 gtcattgaaa aggagctgtt agacagcgcc aagccttagc tatttgaaag attagcaata
    26941 ataaaaaacc tgaacgatct gaacgaggct tctctaagct agctatgact agtcagctta
    27001 gagccttaga acaggtcttt caggtttttt atgtttagct agtgtggtta attaatgatt
    27061 gaagctaatt tcttctagca ggtagtcaat aaatcgctct cccatttttg agaggttagc
    27121 cttttcgtgc ttgataaaga caatctcaat cacatcaggg acatctaagg gaatagcgac
    27181 aatctggtct ccatttagat ttgtgtttaa aataccgctg gcaacggtgt agccatttaa
    27241 gccaatcatg agattaaata gggtagctcg gtcactcacc acaatagact tactgtgagg
    27301 gatatgtgcc atcatctcct ctgagaaata aaaggaattg tgaatcccct gatcatagct
    27361 tagataagga aaatcaagga gatcatcaat ggttaagctg gttttatttg ccagaggatt
    27421 ggacttgctg ataaagatat gcggtgtggt tttaaatagg gtggaaacgg tcaaatgatt
    27481 ttcctcaaac agcttggtaa ggacgtctcg gttgtagtca ttgataaaca aaacgccgat
    27541 ttctgagcga aaatttttca catcgtcaat gatttcccag gttcttgttt ctcgcaagaa
    27601 aagctcgtac tgggtcatat cagcccgctt taataaagag acaaaagcat tgacaacaaa
    27661 ggcgtaatgc tgagaggaaa cactaaagag ctcacgacta gtattgtgat ttttatagcg
    27721 atcctctagc agtgctgttt gttcaataat ttgtctggca taagatagaa actcaacccc
    27781 gtccttggtt aaggtaatgc ccttgggatt acgaatgaaa atagtaatgc ccatctcctg
    27841 ctctaattcc ttgacagcat tagacagact gggctgcgtg ataaataatt gcttagcggc
    27901 ttcgttcatg gaaccgcatt caacaatctt tataatgtat tgtagttgtt ggattctcat
    27961 actgacagtc tatcttaaat agtacaaaga atcaagtgcc tttattagag cttaagacaa
    28021 ggtttcacaa gcggtagcct agcttgtgcg gtgaagctag cttgatgcta gtgttgtacc
    28081 caggtaaaaa agagctggca aataggcagt tttatcgctt tttaccgctt atttttggca
    28141 tgcctgtgtt ttgataaacg gctggtcttg atcggtaaaa agtaatcgtg ataatgtcag
    28201 ataataccta tttttccatt gctcttttaa ttttcttgtg ttatattaat aatattgata
    28261 tatttaatgt tttgagataa agggtggtga tggtgtaata tgactggaca aagtagtcat
    28321 caggtattaa ttcaaaagct gttggtcagc actcactatt tgacattatt tagagatgag
    28381 ctgaagctag ttgagaggac accatctatt ttgggaagtg agtttcctgt ctctcttgtt
    28441 caaacggaat taggtgatat tatcaccttg gtggatacct taaataagca gcagcgcttg
    28501 attgagtcga ccttttggta tgaggagtca gcctttaagc tcatgaacaa ggccttagat
    28561 attgttgata attggataaa ggggatagat ggcttaatta agctctgcca gtccaaggag
    28621 gtctttcagg ccattgttgg tgataaaaga acacgtgttt ttggtgtttt gattgatgtt
    28681 ttttcttccc taaaaattag caccatgtca ttgaaggaat ttgcagctcc ggctgctctt
    28741 tgccattaga ttaagctggg ctaagcttgg atagtggctg gttaagcctg caagttgccc
    28801 ctctcatgac aagtctaggc tttatttagg gtgagcagtg tgccaagggt gtattaagtg
    28861 ctggttgctt tgaagcttcg ccttgctagg ttagctgtga gtgatgtcac gataactgcg
    28921 cgaaacagtt atttctgaat tataatacag gttaaagtag gtacttttaa tgtttttcct
    28981 attgtaaaat ctatacaaaa taggatatat ttttgaaata gctgaacatt aacgtacagc
    29041 aagctttatt ttcttgctaa aaatcttttt tatacctttg tcgtgtgagt aatgtcaaaa
    29101 ccctttgaca agggctgtca aaaaagctat aatgattgag ataagttacc tttaagtgag
    29161 tccagagagg cgagcaaggt acacaggata agatgagagg gtttgctctc ttgattttcg
    29221 tgtagcctcg cttctttgga agtgaggctt ttatggtgtg actttcagtt ggtctcgtgg
    29281 taatgattca taagaccaat aaaccgctcg ttagacgggt gggcatgatt tgtttgggag
    29341 taccccaagc tgcatagaaa ggataggtta tgcgagaaga acgccctatt attgccttag
    29401 attttccttc ctttgaggag gtcaagtcat ttctgtcgct gtttccagct gatgagaggc
    29461 tatacgttaa gattggtatg gaactgtatt atgctgaagg accagatatt gtccgttatg
    29521 tcaagtcctt aggtcacagt gtttttctgg atttgaagct gcatgatatt ccaaatacag
    29581 tcaaatcaac gatggcagtc ctatcaaggc ttggtataga catgacgact gtgcaggctg
    29641 ctggaggtgt agagatgctt agagcagcgc gtgagggctt ggggcagggt ccgattctca
    29701 ttgcggtgac acagctaaca tcaactagcg aagagcaaat gcgtgaggat caaaacattc
    29761 aatccacgct gttagcatct gtgcttcact atgccaagcg taccgctcag gctaagctag
    29821 atggcgtggt ttgctcagcc catgaggtca aggccattaa gtcagaagta ccagcaggct
    29881 ttgtgtgttt gacacctggg attcgcccga caggtgctga catcggagat caaaagcggg
    29941 tgatgacacc tcatcaagct agagctatcg gaagtgacta tattgttctt ggtcgtccga
    30001 tcactcaggc tacagaccct gtcaaggctt atcaccagat taaggcagag tggaaccgtt
    30061 agcagcagga tcatcatgac acatatagct ggactatgac accaaggaaa agaggagaaa
    30121 aatgacacta gcagcacaaa ttgcaacaga tttacttgag attaaggccg tttacctaag
    30181 accaaaggag ccctttactt gggcgtcagg cattacatca ccgatttata cggacaatcg
    30241 gatcaccctt tcttatccaa aaaccagaag cttgattgaa aatggctttg tggagacgat
    30301 taaggcagta tttccagagg ttgaggtgat tgctggcaca gcaactgctg gtattccaca
    30361 tggtgctatc gttgcagata agatggacct gccttttgcc tatatccgca gcaagccaaa
    30421 ggatcatgga gcaggcaacc aaatagaagg gcatgtgcgc tgcgggcaaa aaatggtgat
    30481 tatcgaggat ttgatttcaa caggtggatc agttctggag gcggcagcgg cagctagtcg
    30541 cgaaggtgct gatgtactag gagtggtggc aatttttacc tatgaattgc cagtagcaag
    30601 catcaatttt gaaaaggcag ggctttcctt ggtgaccttg tctaattatt cagacctcat
    30661 taaggtcgct aaggccaagg gctatattga tgctgatggc ttggccctgt taaaaagatt
    30721 taaggaggat caaaagcatt ggcagcatga gagttaaaca gtgctgaaaa gctgctgaca
    30781 tgctgactat gtcttaagga gagaaaaaat gacttacaaa gatttacttg agataggtga
    30841 gaccagttat tatcagacgg atcgcttgac ttactacaaa aatcctgtgg tatctgagcg
    30901 ctattttgat aattacctta gctatcgtag catgccttct ttggctgatt tgaaaaagga
    30961 cttggcctat gtggcaaaag agcagcagga ttatcctagt cactacgcct ttctcttttt
    31021 tgctgaaaat gaagagctaa gtacagacat gcgagcttat ttgacagatc atcactttag
    31081 ccttgaaaag cacctgatct ttaccaatga gctggcaaag cttcacctaa aggagcgtga
    31141 tatatcacca gtcactattg aacagctctc agaaacaagc ttttctgcct atctggctta
    31201 caaatatcag gctaatttgg cttatggtga aacctatgcc aatcaatgca aggctgataa
    31261 tgaagccaat ctattgacaa acggctcaac catttattta gccatcaagg aagggaagat
    31321 tatcggagat attacggctt gggaatgtgg cgactatatt gaaatggacg atttcagtgt
    31381 agatgaggcc tatcgtggtc gtggtatcgg tacagcctta cagcgtaagg ccagtcaagg
    31441 ctataagaag gtcattctca tctcagaaga agctaatcgc gccatgtatg agcaccaagg
    31501 ctatcaggag gttgcttact actggacagc gctaaaaaca tcgactagat aagtgataaa
    31561 gaaacagatt ataggattga aggtgtaggc tcttatgagt atgactcttc aatccttttt
    31621 ttctgagcgc atttgctaat catacctaat gaataagtcg tagcctgtct agtggctcat
    31681 tttaatggcg tcttgctctg ttttatgatt aaatatagag aaaaagctat tgttagggca
    31741 tgcttgttgg tctagcaagg ctgatggatg ataggatagg gaattgatga tttttaaaga
    31801 tgcaacagaa atggcgcagg ctgttcgaga aggtagggtg agcccctcag ccttagtgag
    31861 agacacaatt aaaaaggctc aagcactcaa tcctgagttg aatgctatta cctcagagcg
    31921 tttttcagaa gctcttgctg aggcagcagc aagggatttt tctggaaagc catttgctgg
    31981 tgtgcctatt tttctaaagg atttagggca ggagcaggag ggccaattgg ccactgcagg
    32041 atcagtgtta tttaaggatt atcgtgcctc aaaaacggat tatgttgtgc agcgactaga
    32101 ggagctgggc tttattattt taggaagaag caatacacct gaatttggct ttaaaaatat
    32161 tagtgatagt cgcttacatg gtccggtaaa tctgccacag gacaagagcc gtaatgctgg
    32221 tggttcatca ggtggggcag cagctcttgt gtcctcagga atcaccttgc tggctcctgc
    32281 tagtgacgga ggaggatcca ttcggattcc tgcctccttt aatggcttga tcggtttaaa
    32341 gccaagcaga ggaagagtgc ctgtggggcc aggctcttat cgtggctggc agggggcgtc
    32401 tgttcatttt gctctaacga ggtctattcg agacacaagt cgtcttcttt atcacttgca
    32461 ggtttatcag gtagaaagcc cttttccatt agtgccatta accaaagaag agctttttca
    32521 ccctttagac agacccttaa ggattgctct ttatgatcac atgatagatg gaactaccgc
    32581 ctctatagat gctcagacag ctttaaccga ggcctgtcat tttctaaaag agatggggca
    32641 tgaggttgtg cgattagata agcttcctct agatatacca aaggttatga gggattacta
    32701 cctgatgact agtgttgaga cagctgctat gtttgctgat agccaagaag cccttggtcg
    32761 tcaggtgacc aaagcagata tggaggtcat gacctgggct atctaccaag cgggtaagga
    32821 tattcttgct tcggtctatt ctcaggcgct gcagcgctgg gaccattata gtgctgaaat
    32881 ggcaagcttt catgagcagt atgatctttt gctgaccttt accgccaata cgcctgctcc
    32941 aaagcatgga cagttccagc caagcaagga gctaatagat aagctggcta aggcggaatg
    33001 ctacccctcc agtcagcgcc tagcgctagt agaagccatg tttgagcaga gcttgttcat
    33061 aaccccttac acagctttgg caaatctgac aggccaacca gctcttagtt taccaaccta
    33121 tgaaacgtct gctggattgc cgatgggcat tcaattgata gctgctaaag ggcgagaaga
    33181 cttattgctg ggaatagcta gacagtttga acgggctgga ttgttaaagc tacctggtta
    33241 aatattataa aacagagcta atctattata ggttagcttt tttgttaaat cgagcatatc
    33301 tagtctctta taagattagt caatgctata ctgtcattaa taatgaaaaa ggagttcttg
    33361 atgaaaaaag gagttgcttt actttctgtt agcttggcga gcttgctgtt agccgcctgt
    33421 gggtcacagc catcagctca aaaaacaagc tgggaaaaga ttaaagataa aggtgtttta
    33481 aaggttgcta cgcctgcgac ctaccagcca acatcgtact ataatgatgc caatgaattg
    33541 gtcggctatg aggttgacct gatgaaggaa attgggaaac gccttgatct taaggtgaag
    33601 ttcattgaaa caggctatga tcaggctttt acttcggttg atagcggtcg tgttgatgtt
    33661 tctctcaata attttgacat tacagccaag cggcaaaaaa aatacaacat ctcaacgcct
    33721 tataagtatg gtgttggggg aatgattgtt cgtgctgatg gcagctcagg cataagcaag
    33781 gctgacctaa gcgattggaa agggaaaaaa gcagctggcg cctctggtac agaatacatg
    33841 aaggttgcca agaagcaagg tgctgaatta gtcacttatg ataatgtgac gggtgatgtt
    33901 tacctgaacg atgttgctaa tggcagaaca gactttattc ccaatgatta tcctgcacaa
    33961 aagctttttg tggattacat gaagtctcaa aatcctaacc tcaatgtcaa aatgagtgat
    34021 gtgctgtata atccgacagc acagggcatt atcatgagta aaaaagatga cacccttaag
    34081 aaaaagattg atgcggtcat caaagacatg aaacaagatg gcagcttgaa aaccatttca
    34141 aagacatact atgctggtca ggatttgaca gttccttttg gtaaggacaa gaaaattcca
    34201 gtcattgatg ccagtgatgt ggactagtgc cttagacaaa ggagctctaa agcgatgctt
    34261 aatcttagat tgatactaga gagcttgggc tttgttttgt caggtttgcc ctatacctta
    34321 ggcatttctt ttttaagctt tctaacaggc cttttgctgg gcttgctttt agccttttta
    34381 aggcgttcta ctagtcactt tagtcattat ctggtcagga gctatgtgtc cataatgcgt
    34441 ggcgttccta tgattgtggt gctctttgtc ctttattttg ggcttcccta ttatggctta
    34501 gaactgtctg ccttgttatg tgcctatttg ggcttttcac tggttagtgc agcctatatc
    34561 tctgaggtct ttcgtgcctc gattgatgct attgatcagg gacaatggga ggcagcaagg
    34621 gctttggggc tgccttatgt cagcattgtc aagcatgtga ttctgcctca ggcctttcgt
    34681 attgctattc cgcctttagg aaatgttgtg attgatatgg tcaaaagttc gtctttggca
    34741 gctatgatta ccgttcctga tatttttcaa aaggctaaaa ttattggtgg cagggagtgg
    34801 gattacatgt ctatgtatat cttggttgcc tttatttatt gggtgattgc ctttttgctg
    34861 gagcgctgtc agggcttttt agaaaagagg ctgcgcttac tctcttaaaa accgaatatt
    34921 taccctagaa atattgtatt tctagggttt ttatgataaa aatatgatag actaaagtag
    34981 cctaatcagt tagttagctt tgtcaagaac tgactggcta gagtgttgga ggtaggatat
    35041 ggcagactct attgtatttc ggaaaaatca tatgatttca actcaggcct ttgctcgagt
    35101 gctggaagcc tcagggatta aaagaccgac taaggacgag gctagattat cgcaaatgct
    35161 aaagcattcc aattatctat ggacagcatg ggaaggtgac aagttagttg gtgttgctag
    35221 agcccttact gactatgctt atgtctgcta tatttctgac ctagcagttg atcaggcata
    35281 tcagggtcaa gggataggca agcaattgct gtcttttatc tcagaggatc ttggagatgc
    35341 tgttgctctt gtattgctgt cagcaccttc ggcgatgtcc tattacccta agcttggctt
    35401 tgaacaatca gacaaagcct tcattattcc acgaaaaccg ttttagagag gtatctaatg
    35461 acacattcag cttggcatga tgagattaag caagtgttac ctaaggatta ttatcggcgt
    35521 atcaatcgct ttttagatga ggtctatgcg actggagtgg tttacccgcc cagagacaat
    35581 gtgtttaagg ccttacaggt aacgccatta gaagagacaa gagtgcttat tttagggcag
    35641 gacccttatc atggccctct tcaagctcag ggactttcct tttcagtgcc tgactccatt
    35701 cctgctccgc catctttgca aaatattttg gaggaattag cagcagatat tggagtaagg
    35761 aatcatcacg atcttagcag ctgggctgag cagggagtgt tgctcttgaa tgcctgcttg
    35821 accgttccag aaggacgcgc caatgggcat gcaggtctca tctgggagcc ctttaccgat
    35881 gcggttataa aggtcttgaa tgctaaggat aggcctgttg tgtttatcct ctggggagcc
    35941 tatgcgagaa gaaagaaggc cttgattact aatccgattc accatgttat cgaaagccct
    36001 caccctagcc ctctgtcagc ctatcgtggc ttttttggca gcaagccctt ttcaagagct
    36061 aacgccattt tagaaaaaga aggcctagga cagattgact ggctgcgcta ggcattgagg
    36121 caggctatta tggctaagca ggacgattta ccaataaagt atccggcttt ggagacttgg
    36181 gtatacctag ctaaatagag attgatgata tcagggatca agacagttac gtccgatatg
    36241 tcaagcaaaa caaataatca ctgcctagat aaatcagaaa ttgctagggt tatgcttgat
    36301 tatcctgata agcagataag tagatttgac ataggagggg tcatgttatt aattaaaaat
    36361 gggcgtgtga tggatccaaa atcacagcta gatcaggtgg cagatgtctt aattgataat
    36421 ggaaggattt tacggattgc tccagacatt gagcatgatg aggtagagca gatcgatgcc
    36481 agtggacttg ttgttgctcc tggtttagtg gatattcatg ttcattttag agagccgggt
    36541 caaacgcaca aggaggacat tcatacaggt gctctggcag cagctgctgg tggggtgaca
    36601 acagtagtca tgatggcaaa caccaatcct gttatatcag atacggaaac cttacaggct
    36661 gttctagcaa gtgctgctaa agaaaaaatt aacatttata ccaatgctag tgtgaccaag
    36721 cggttcaatg gccaagagct aacagacttt aaagcgctct tagcagctgg tgcggtcagt
    36781 ttttctgatg atggcattcc tttagagagc tccaaggtct taaaggaagc attggatttg
    36841 gctaaggcca acaagacctt cattgccctg catgaggagg atccccaatt aaacggtgtc
    36901 cttggcttca atgagcatat cgctaaggat cattttcatt tttgtggcgc tactggtgtg
    36961 gcagaatata gtatgattgc cagagatgtg atgattgcct atgatcgaca agctcatgtt
    37021 catattcaac atttatctaa ggctgagtct gttaaggtag ttgcctttgc tcagcagtta
    37081 ggtgccaagg tcacagccga ggcaacaccg cagcattttt ctaaaacaga agacctttta
    37141 cggcttgcag gggcaaatgc caagatgaat ccgcctctaa gaacagaaca agatagatta
    37201 gcagttattg aggggctcaa atcaggtgtc atagctatta ttgcaacgga tcatgcacca
    37261 catcatcgtg atgaaaaggc cgttgctgat ctgaccaagg caccatctgg aatgaccggc
    37321 ttagaaacct cattgtcatt aggcctgaca aatcttgtgg agccgagcca tctttcattg
    37381 atggcgttat tagagaaaat gaccattaat ccagcctcac tatatagctt tgatgctggt
    37441 tatttggctg agtctggccc tgctgatctt gttatttttg ctgacaagga ggagcgtttg
    37501 gtaacagaag cctttgcttc aaaggctagt aattcacctt ttattggcga aaccctaaag
    37561 ggagttgtga aatacaccat tgctaaggga caaattgttt atcaggcaga caactaatca
    37621 acacttaaaa agctgagcat ctgatagtaa ctgatgctca gctttttgat ttagtgatgg
    37681 cttgcgggct gctgcttgct taagttcaag ccccaaggaa tgagattttc agattgctgc
    37741 ttgattcgct tcatattatc ctgatgcctt aggataatga ttgctgctag cacaacgatg
    37801 gtaatggtta atagccaatc gtagctaggc aataaaaagt gggcggcagg aaaagtcaga
    37861 acgctaatca cagctactac agacgctgtt agactagcta gtgaaatcat gctaaataaa
    37921 taaagcgtta gcacaaacac agccgctaaa aaaaggagat agagtggggc aaagcctagc
    37981 aagacaccag cactggttgc gactgccttt cctcccttga agccagcgaa aataggaaag
    38041 gtatgcccta ggacagcaaa aaagccaata gtaattggtg agatattgct agcgccaacc
    38101 aaaaccggaa gaagcgtggc aagcgtgccc ttaaaaatat caatcaataa ggttgcagca
    38161 ccagctttta gcccaagaat ccgaaacgta ttggtcgtac cggtattacc tgagccatgc
    38221 tcacgcaggt tgatgttata gaaatactgt ccaatccata agcctgttgg aatggagcca
    38281 agtaaatatg ctgtaagaat taataggatc aatttcataa catacattat atcataatga
    38341 ttgatttaag cggaagcagt tacaaagaat tacgaaaaaa tcttaaatta ttttgcaaaa
    38401 ttctcaaaaa acctgtaaga taaaaaagat gaaaacgtct ggaggtcaac ttggctaaga
    38461 aagaaataag cataacaaat tataatgatg atgccattca ggtcctagag ggcttagagg
    38521 cagttcgtaa aagaccaggg atgtatatcg gatcaaccga tgcaaccgga cttcaccatt
    38581 tgatttggga gattgtcgac aatgctgttg acgaggcctt atctggcttt ggaaatgaga
    38641 tcgatgtgac gctaaacaag gatggttctg ccaccatttc tgacagcgga cgaggcatgc
    38701 cgaccggaca gcacgccctt ggtataccaa ctgttcaggt catctttacc atcttgcatg
    38761 caggtggtaa atttggtcaa ggaggctata aaacctcagg aggcctgcat ggtgtgggct
    38821 cttcagttgt aaatgcccta tcgtcatggc tagaggtgga aatcacgaga gacggagcgg
    38881 tttacaagca gcgctttgaa aatggcggta ggccagtgac aggcttagaa aaaatagcta
    38941 cagctccaaa aagcaaatca gggacaaggg ttactttcat gcctgatgac aagatttttt
    39001 cgacaactga gttcaagtgg aatactatcg cagagcgtct aaaggaatct gcttttctgc
    39061 taaagacggt taaaatgacc ctgactgatc tacgaggtga cgatccggtc gttgaggaat
    39121 ttcattatga aaatggtgtt caggattttg ttgcctatct caatgaggac aaggaaacct
    39181 tgactcctgt gatttacatg gaagggcagg agcaggattt tcaggttgag gtcgctttgc
    39241 aatacaatga tgggttttca gataacattt tgtcctttgt taacaatgtt aggacaaagg
    39301 acggtggcag ccatgaaact ggcttaaaat cagctattac aaaggccatg aatgactatg
    39361 cccgcaaaac cagcctacta aaggaaaagg ataaaaactt ggagggctca gattatcgtg
    39421 agggcttgtc tgcagtgtta tcgatccttg taccagagca gcatttgcaa tttgaagggc
    39481 aaacaaagga caagctagga agcccactgg caaggccgat cgttgagagc attgtatcag
    39541 aaaagctgac cttcttttta cttgaaaatg gtgagctggc aggtcatttg attcgtaagg
    39601 ctatcaaggc aagagacgcg cgtgaggcag ccagaagagc gcgtgatgag tctcgaaatg
    39661 gtaagaaaaa caaaaaggac aaggggcttc tttctgggaa attaactcca gcccagtcca
    39721 aaaatcctaa gaaaaacgag ctgtacctag tcgaggggga ctcagctgga ggctcagcta
    39781 agcagggcag ggatcgtaaa tttcaggcaa ttctcccctt acgtggtaag gttttgaaca
    39841 cagaaaaggc caagatggct gatattctca aaaatgagga aatcaataca atggtttata
    39901 ccattggcgc aggtgttggt gctgatttca atcttgatga tattaattac gacaagatta
    39961 ttatcatgac cgatgctgat acggatgggg ctcatattca gaccctgctg ctgacctttt
    40021 tctaccgtta tatgcggccg ctggttgaag caggacatgt ctatattgcc ttgcctcctc
    40081 tttataaaat gtcaaagggt aaaggcaaat cggagaaggt ttcctatgct tggacagatg
    40141 gtgagctgga ggatcttcgc aaggaatttg gtaaaggtgc aagtctccaa cgctataagg
    40201 gacttgggga gatgaatgcc gatcagctat gggaaaccac gatggaccct gacacacgaa
    40261 cccttatccg agtgacgatt gatgacctgg ctagggcaga gcgacgcgtt tcagtcctca
    40321 tgggagacaa ggctgcccca cgccgtcaat ggattgagga caatgtcacc tttaccttgg
    40381 aggaaaatac ggttttttaa ggcatttttc ctaaggaggg ttctaaaata tctcatatca
    40441 aattgctatt catgtgctca gcattcattt atcaaggatt gtaatcattg aggtaacagt
    40501 gatgaagcta gatatttgtc aacaaagcta cagtcttcag tggggaggca cctattattt
    40561 tgcattgaca gattatccca atatcaaggc ttgggaactg gaaaagctag cagccttttg
    40621 tgcctacgaa aaatggaatc atcgtcaaac agacattagc tgtcaggaca gcaagcttct
    40681 tgaagaggtt catcaatttc ttgaagcaca tgcttgtgcc tatctcttta ggcctagctg
    40741 taaattggtg gcttcaacat ttaacatcaa tggagaggca gtctgttgtc cttatttaag
    40801 tcatacctgc actgtagcgg ctgctctaag catttttaag acaggaaggc tattgtctgc
    40861 tgtaagagct tttggggtaa cggcacagga gttggctagg agtgatcgaa atgctgctgg
    40921 tgatcctgct gattattttc attatgtgat gcttggctgg tccaatacga cctcaggcta
    40981 tcgcttggct atggagagat tgcttaatcg tatgccaaat gaaaaggact taagagagca
    41041 ttttgtaccc ggagttagct ttcactatag ctattctgat atttgtcaga tgaaaggcta
    41101 tgtttttgat ggctatcacc ctgccaagat caaagacgag cttagtttgg aggaattgca
    41161 ggcttgcatt attcctaaaa gctggcagca gcgctttgaa gcaattattc caaaggcctt
    41221 acgctcaagg gttcattacc tagactataa aggcgaaggc ttggtcgagt ggtctgatag
    41281 ggtttatcag ctgttaagag tgatcagtga cagctagctg taaataggct agctttatac
    41341 tattttttga atataataga caatctaaca gaaaggaaag ctcagtgaga ggtctcttgc
    41401 tgggtgtggg atggatttcc tagaaactgc taatcctagc gataggggag cgtagcgagc
    41461 ccattctgaa agctcctgcc gtagtgaaaa gaagataatc gcttacgatt atcttcgagg
    41521 gaaatttcga gccgaagtct cgaaatttag gaatggaacc gtaggttcgc ttctgtcccc
    41581 actacctaaa ggaactttca aaaaaaacta attaaagaaa gagatatctt tctgaaagaa
    41641 acaaagaaag gaatgttcag ctagtttact aactgaacac gggactattt ttcctagaaa
    41701 aatcggtaac ctcctagtgt ccaaggacac gtcgtcagtt ccagcatttt ttacggaaaa
    41761 atttcgcaag cgaaacgtcc ctttgtatct tatgagtaat attcaaaaca tgtcccttga
    41821 ggacatcatg ggagagcgtt ttggacgcta ctccaaatac atcattcagg agcgagcgct
    41881 tcctgatatt cgagatggtc taaagcctgt tcagcgccgc attctttatt ctatgaataa
    41941 ggacggtaat acctttgaaa agggctaccg caagtcagcc aagtctgttg gtaatatcat
    42001 gggcaatttc cacccgcatg gagattcttc gatctatgac gctatggtac gcatgagtca
    42061 ggattggaag aatcgtgaaa ttcttgtgga aatgcatggc aataacggct cgatggacgg
    42121 tgatccaccg gcagctatgc ggtacactga ggcaagatta tctgaaattg ctggttacct
    42181 gctacaggac atcgataaaa aaacagtgcc atttgcttgg aattttgacg ataccgaaaa
    42241 agagccaaca gtattgccag ctgcctttcc aaatctattg gtcaatggct catcagggat
    42301 ctcagcaggc tatgctacag atattccacc acataatttg tcagaggtga tcgatgctgt
    42361 tatttatatg attgaccacc caaatgccaa gctggataag ttaatggagc tattgccggg
    42421 tcctgatttt ccaacaggtg gtattatcca aggagcagcc gaaattaaaa aagcctacga
    42481 aacaggtaag agccgcgttg ttgttcgctc cagaactgaa attgaggatc taaagggagg
    42541 caagcagcag atcattgtga ccgaacttcc ttatgaggtc aataaagctg tcctagttaa
    42601 aaaaattgat gatgttcggg ttaataacaa ggttccagac atagcagagg tgcgtgatga
    42661 gtcagaccgt acagggctac gcattgctat tgagctcaaa aaagacgctg acagccaaac
    42721 catcttgaat tatttgttga agtataccga gcttcaagtc aattataatt ttaatatggt
    42781 tgcgattgat cattttacgc ctcgtcaggt tggattgcaa aaaatcttat caagctatat
    42841 cgctcaccgc aaaagtatta ttatcaagcg ctctcagttt gacaaggaaa aggctgaaaa
    42901 gagattgcat attgttgagg gcttgatacg tgtcttatct attttagatg agattatcgc
    42961 gctgatccga gcttctgaca ataaggctga cgccaaggaa aacctaaagg tcagctatga
    43021 tttttcagag gaacaagcag aggctatcgt aaccttacag ctttatcgac tgaccaatac
    43081 agatattgtt accctccagc aggaagaaca tgacctaaga gagctcatca caactctctc
    43141 tgccattatt ggtgatgaag caaccatgta taacgtgatg aagcgtgagc taagagaggt
    43201 caagaaaaag tttgcagggc cgcgtttatc agagctgcag gctgaaagcc aagcgattga
    43261 aattgattct gctagtctta ttttggagga agaaaccttt gtcagtgtga ctcagggagg
    43321 ctatatcaag cgaacaagcc ctaggtcatt tcacgcctca agccttgagg aaattggtaa
    43381 gcgtgatgat gatcatctga tctttgttaa gcaggctaag acaacagacc acctgttact
    43441 ctttactaat ttaggtaatg ttatttaccg tccggtctat gagctgactg acttgcgctg
    43501 gaaggacatc ggggagcatt tatcacaggc tattgctaat tttgctgctg atgagctggt
    43561 gatatatgct gagttgatcc agtcctttga agagggacta tatatctcag tgacacagca
    43621 tggactgatt aaacggtttg agcgcaagga gctgacgcct tggcgaacct acaaatcaaa
    43681 atcaattaaa tacgccaagc taaaagacat agatgatcgc attgtggcaa tagcaccaat
    43741 tatcatggaa gatcttcttt tggtgacgca gcagggctac gccttgcggt tttctagcca
    43801 agaaataccg attcagggcc taaaggctgc cggagttaaa ggaattaacc taaaggctca
    43861 ggattacttg gtttctgcct gcccagtcaa tgctgattcc ttctttgtgc tgacgcaaag
    43921 aggagcacta aagcgagtgg cgattgctga tattccacag accagccgag ctaacagagg
    43981 tctgccggtg ttacgagaat taaagaccaa gccacacaga gttttcttgg caggaatggt
    44041 aaaaggagat actacaacag gtaccattga cttatttaca catgattcag aggacacagc
    44101 tagtgaccag caattagagg ttattagtaa gactggtcaa caataccagc ttgctctcaa
    44161 tagcctgtct ctatcagata ggacaagtaa tggctccttt atttcagaga gcatttcaga
    44221 tcaggaggtc gctgctgcaa ggctcatcta gccaaagctt tttcgctgta ccagtgaggg
    44281 ctctgagtct ttcatcgaaa aaagatgcaa aacaatgaag aaaagaatac aaaaagaaaa
    44341 gaggtaggat aatgacaaca gctattgatt gggaaaactt aggctttgaa taccgtaagc
    44401 tgccatttcg ctatgtatca tattacaagg acggcaaatg ggacgcaggt cgcttaacag
    44461 aagatgctac cctgcacatc tcagaaagtg caccagctct gcattatggg caacaagcct
    44521 ttgaaggctt aaaggcctat cgcactaaga acggctctat tcagctattt cgcccagacc
    44581 gcaatgcagc tcgcttacag gcaacagctg accgtttgct gatgccacag gtatctaccg
    44641 agcaattcat tgacgccgtt aagcaagtgg taaaggcaaa tgaggatttt gtaccgccat
    44701 atggaactgg tgctaccctt taccttagac ccttgttaat tggtgttggc gatattatcg
    44761 gtgttaagcc tgctaacgaa tatatattta tagtttttgc catgcctgtt ggcaattact
    44821 ttaaaggcgg gcttgcgccg accaacttta tcgtctctga ggattatgat agagcagctc
    44881 cttatggcac tggagctgcc aaggttggtg ggaactatgc aggtagctta ttgccaggaa
    44941 aagcagctaa gacagcaggg tattcagatg tgatttacct agatccagca actcacacta
    45001 agattgaaga ggtcggagcc gctaatttct ttggcatcac tgccaataat gaatttatta
    45061 cgccgcttag cccatcaatc ttgccttcaa ttaccaaata ctccttactc caattagccg
    45121 aagaaaggct tggtatgacc gctattgagg gtgatgtgcc gattaatgat ttggaccgat
    45181 ttgttgaggc aggagcttgt gggacagctg ctgtgatctc accaattgga ggcattcagt
    45241 atcaggataa gctacatgtc ttttacagcg agactgaggt tggtccagtg acacgtcgat
    45301 tatacgatga gctggtcggt atccaattcg gtgatatcga agcaccagaa ggctggattg
    45361 tagctattga ttaaaataag tgaagcttgc tattgcaagc tcttttgatt ttgtgtaaaa
    45421 tagacaaggc gaggtgaagt gatgagtaaa aaagagaaaa aaattgaact gcaattatgc
    45481 gatcaacaag taacagtcaa caataccaag atagacggtt atcagttaca aattggcaag
    45541 cgtgtcgttg gcgagattgc agagcttgat ggcaagtttg ctgtcttaaa agacagcaca
    45601 gtagatgctt tttttaaaac attagagcaa gcagttgaaa atattattga aaactataat
    45661 ttgaaccact aaaaatgctt aaaaagactt gtcagcttac aaaaactatg gtagaatagt
    45721 ttttgttgtt acggaaagat agcgaagagg ctaaacgcgg cggactgtaa atccgctcct
    45781 ttgggttcgg gggttcgaat ccctctcttt ccatgcctaa gctattaggt tcattgtttt
    45841 aatgatgata ttggggtata gccaagcggt aaggcaaggg actttgactc cctcatgcgt
    45901 tggttcgaat ccagctaccc cagtcagagg tatcagatta gcgtctgaga tcgtcaagga
    45961 taaaagttgt tgtcattgcg ggttaccttg agaaaatata ttgttatcaa aagctagcat
    46021 aagctagctt ttgttggagg attttttaga atgaatgaat ttgaagattt gctaaacagt
    46081 gttagcgaag tcaatcctgg tgatgttgtc actgcggagg ttttgacagt tgataacggt
    46141 caagcaaacg ttgttattga aggcacaggt gttgaaggcg ttttgacact tcgtgaattg
    46201 actaacgatc gtgaagctga tattaatgac tatgttaaag ctggcgacac cgttgaagtg
    46261 cttgttcttc gtcaagttgt aggtaaagat actgatacag ttactttcct agtatctaaa
    46321 aaacgtttgg aagctcgtaa ggcatgggac aagcttattg gtcgtgaagg tgaagtcgtt
    46381 actgttaagg ggactcgtgc tgttaaaggt ggactttcag ttgaatttga agggcttcgc
    46441 ggatttatcc ctgcttcaat gattgacact cgttttgttc gcaatacaga aaagtttgtc
    46501 ggtcaagaat ttgacgctaa aatcaaagaa gttgatgcag cagaaaaccg ctttatctta
    46561 tcacgtcgtg aggttgttga agaagcagct aagcaagcac gtgacaaagt cttttcaaca
    46621 ctttcagaag gttcagtggt aactggtact gttgcgcgtt tgacaagctt tggtgctttt
    46681 attgatcttg gtggtgttga cggtcttgtt cacgtaactg agctctcaca tgagcgtaat
    46741 gtgtcgccta aatcagttgt ttctgttggt gaagaggttg aggtgaaggt acttgctctt
    46801 gatgaggaag caggtcgcgt atcactatca cttaaagcaa caacacctgg accttgggat
    46861 ggcgttgagc aaaagcttgc acaaggtgat gttatcgaag gtaaggttaa gcgcttgact
    46921 gactttggtg cttttgttga ggtattacct ggaattgatg gacttgtaca catttcacaa
    46981 atctcacaca agcgtgttga aaatccaaag gacgtgctta ctgtaggtca agaggtaact
    47041 gttaaggttc ttgacgttaa cgctgctgat gagcgtgtat cattgtcaat caaggcactt
    47101 gaagagcgtc cagcacaagc agagggtgaa aaggaagaaa aacgtcaatc acgtccacgt
    47161 catcaaaaac gtgaagctaa gcgtgattat gagcttccag aaacacaaac tggattttca
    47221 atggctgacc tttttggtga tattgaatta taatactata aaaa
//
LOCUS       DARYYD010000011        43812 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.011, whole genome shotgun sequence.
ACCESSION   DARYYD010000011 DARYYD010000000
VERSION     DARYYD010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43812)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43812)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43812
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.011"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(21..1292)
                     /locus_tag="TV188_000536"
     CDS             complement(21..1292)
                     /locus_tag="TV188_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEL1533920.1"
                     /translation="MPDNLAIRMRPRTITEVIGQQHLVGEGKIIDRMVKANRLASMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATIDNKKRLQEIAEEAKFSGGLVLLLDEIHR
                     LDKSKQDFLLPLLEHGHIIMIGATTGNPFFSVTPAIRSRVQIFELEPLSPEEIKQALK
                     LAITDKERGFAFDVTLDEAAFDFIATATNGDLRAAYQSLDLAVMSTQPDTEGIRHISL
                     NTVENSLQRSYITMDKDGDGHYDILSALQKSIRGSDVNASLHYAARLIEAGDLPSLAR
                     RLTIIAYEDIGLANPEAQIHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYM
                     AMDAALADLRQHGHLPIPRHLRDGHYAGSKELGNAQHYLYPHAYPEKWVKQQYLPDHL
                     VKKNYFNPNETGKYERALAANKARIDKLSSS"
     gene            complement(1285..1893)
                     /locus_tag="TV188_000537"
     CDS             complement(1285..1893)
                     /locus_tag="TV188_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEL1533921.1"
                     /translation="MILLIDNYDSFTYNLAQYLSAFDQTIVLTNQDPKLFDLAKQADA
                     IVLSPGPGWPKAANQMPSLIRAFYDQKPMLGVCLGHQAIAEALGGRLRLAKRVMHGKQ
                     SILERQAPAKLFQQLPKQLTVMRYHSIVVDDLPADFVITARDFEDNEIMAFEHRQLPL
                     FGLQFHPESIGTADGRTMIANFMAVVKKHHSQQKQGREEYNA"
     gene            complement(1934..3670)
                     /gene="pabB"
                     /locus_tag="TV188_000538"
     CDS             complement(1934..3670)
                     /gene="pabB"
                     /locus_tag="TV188_000538"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEL1533922.1"
                     /translation="MHIKTIIDFKELGQRYIFQAPIVELVAKQIDQVGQVLEQVNQFQ
                     DLGYYVVGYLSYEAAACFDKKLTTHNKRLGQEYFAYFTVHDSCQLEDFPLYHDSMTIP
                     NSWTSATQEEAYQEAIAQIHQEMRQGNTYQVNYTIQLSQRLNAKDSLAIYHQLVIEQA
                     AGYNAYIAHDDFAVISASPELFFKQEKNQITTRPMKGTTKRGYNLELDQQEHDWLQAD
                     PKNRSENMMIVDLLRNDMNKICQTGSVTVTQLCQLEQYSTVWQMTSTIVGMLQDQCRL
                     YDILQALFPCGSITGAPKVSTMAIINRLEPKPRGVYCGSIGICLPDGRRVFNVAIRTI
                     QLSYDQAIYGVGGGITWESCWQDEFEEIKQKSSFLNRQSIDFTIKTTAKVEQQSLIYL
                     DQHLNRLREAARYFAYPYDEELLTDRLQAYLKGKDSSPYRLTIAIAKDGQISLTDQSL
                     EPLQKDFLKARLVRQSSDVKKLPFTYFKTSHRPHLSVKPYEQVFVAADGTLLETSIGN
                     LFVQIEQTLYTPPVSAGILPGIFRQELLRQGLAQEKELKLSDLDKAEAIFGGNAVRGL
                     YSLTIEDTTLPQ"
     gene            3819..4289
                     /locus_tag="TV188_000539"
     CDS             3819..4289
                     /locus_tag="TV188_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEL1533923.1"
                     /translation="MAKYGFLSVLEEEMDKHFHYDYAMDWDKKNHAVEITLVLEAQNQ
                     SAVETIDDQGQLSKEDIVFEDYVLFYNPEKSQFQAADYLVAIPFEPKKGFSREFLAYF
                     AQFLNDVAIEGHSDLMDFLADDSKLDFSLEWNEEAFEEGQVGLEETELYSYPRY"
     gene            4291..4635
                     /locus_tag="TV188_000540"
     CDS             4291..4635
                     /locus_tag="TV188_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009910982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEL1533924.1"
                     /translation="MLHEMMLTPRPFAMIEAGVKTIELRLNDEKRQAIKVGDWICFYC
                     TEDHSHILQAEVVGLHYFDDFAKLYQALPLEKCGYRNEELALARPEDMEQYYSKEQQA
                     QYGVVGIELRLC"
     gene            4652..5080
                     /locus_tag="TV188_000541"
     CDS             4652..5080
                     /locus_tag="TV188_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1533925.1"
                     /translation="MKLLDKTVHFSGAKLALISNGKILTILRDAIPTIPYPNMWDLPG
                     GGRENAEAPFDCASRECYEELGLALTKDAVVWERVYPGLVNPDSQSVFLVALMNQDMI
                     DHIAFGDEGQGYQLMAIDDFLADDRVIPQLKARLADYLRK"
     gene            complement(5278..7815)
                     /locus_tag="TV188_000542"
     CDS             complement(5278..7815)
                     /locus_tag="TV188_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1533926.1"
                     /translation="MKQHQRFLSLVGLLLACNLALTACQTHSQKGHSQEPKKHQKATK
                     KKKQKSSKTAKKRERHQVPGIDVPTDDGFLLTSESQIERKTDTGIIVKHGDHKHFFFY
                     SDLKGTKWAYLIPKDYKEAQPASNQAARSGSVVSTGHAGDGYVFNPADIVAEDAYGYT
                     VRHGDHYHYILKSSLPSATINHIASTTPHFPSTPPSIHQQGGIPGIDFKTSDGFLFDG
                     TNISGVTDTGILVKHGNHLHPISFEDLKRSKWAYLVEQYKKKDHTKPQEGDYRAYIAY
                     LAKELKVDQARIKQVNVDGQVGFEYPHEDHTHVIWLKDIDLSKPFKTPEEQILKKIDG
                     ETFEQRKERLIKEFMDRFKVRREDISIEGNYMTISHGDHAHIYKIDPELPDDPERNVK
                     TESTNLEVETQLVYGPFYTENSSENLTRDGVYKKYHPEGIKNIKNFIHVLFSTNSEYG
                     DIEVNGIKTKRVHYLVRKDLDWKDLNIQRPEAIKHEGRIFKGWSAELPTAGKMDREHQ
                     RFYVDFDKVRKQPTKAVYGPGDDVSDLDLENYVPVWFTTIFNGRLKLNGVTQGGFFYN
                     VRSGLTWKEAKEQGLVIPEPVPDPGYEFIEYRSGVNLANNFNLTDFAKRFSITQNEND
                     KVAFTGLFSAAFGTTAPYIGPYIAVNPDKPTDLEDPSRHPNYYFHDPRHYVAVAFKAG
                     EGGQLISRAGKGKTAVYLVRKGHSLHTAGILPPSVQPDAGYKRDYNKPIISTEEYDKE
                     VTEDIVYNVNFDKITNNDVTGNSNHSGNTWLPGDPLPKEPQTPNHTGSTGSWLEEFVA
                     PVSDSDEDDLLAPDPELVGKTPVSDKPASYFLGESETASSTSVASNS"
     gene            8378..9331
                     /locus_tag="TV188_000543"
     CDS             8378..9331
                     /locus_tag="TV188_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011055040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEL1533927.1"
                     /translation="MKAWQELTITVHREAEEAVSNLLIEAGSQGVAINDTADYIGQED
                     RFGELYPAVEQSEMVTITAYYPSSADIDDIRQTINQGLNRLKQCDVELGELTLTNQEL
                     AEEDWADNWKAYYEPARITHDLTIVPSWTDYEATAGEKIIRLDPGMAFGTGTHPTTKL
                     SLFALEQVLRGGETVIDVGTGSGVLSIASSLLGAKEVFAYDLDDVAVRVAKDNIALNQ
                     ATDNIHVAAGDLLKGLTQEADVIVANILADILVHVTADAYRLIKSEGYLIMSGIISEK
                     LDMVKQAALNAGFLLETHMLQGEWNALIFKKTDDLSGVIGG"
     gene            9331..10077
                     /locus_tag="TV188_000544"
     CDS             9331..10077
                     /locus_tag="TV188_000544"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEL1533928.1"
                     /translation="MQQYFIKGRAEKIVQLTDKDTIKHMFQVMRLTDKEELVLVFDDG
                     IKRLARVSDSSAYEVELIKELEENLEMPVEVTIASGFPKGDKLDVITQKATELGAAAI
                     WGFPADWSVVKWDSKKLAKKQEKLAKIALGAAEQSKRNRVPEIQLFDQKGELLKQLKQ
                     FDKCFIAYEEAAKAGERSTLARELAGLSPGQKVLFIFGPEGGISSKELASFKQAGAIT
                     VGLGPRIMRTETAPLYALSAVSYALELMSS"
     gene            10326..11330
                     /locus_tag="TV188_000545"
     CDS             10326..11330
                     /locus_tag="TV188_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1533929.1"
                     /translation="MVTIKDVARLAGVSPSTASRAINDSDMISQATKERVKKAMEALD
                     YSPNYSAQNLVKRKSNTVGIILPVREGQDSLGNNPFFMQIIQGIAAVCTDQGYMVALA
                     TGRSEAELLKNVQNMIRSGNIGKLIFLYSKTDDQVFDFVKRQRVDCVVVGQSTTKDPG
                     NAKFVNNNNHQAGYDAAAFLLQKGYEAIVYAYTDMAELVQAERYKGYAELMTSKALAA
                     QALCVTLKDDRKSQKQLLDQLAKRSKVAFVVCDDVLAIHLQRLIKQVAADTQLAIVSF
                     NNSVLAELASPALTSIAIFPYQLGEQAAELVLSSAAPSPQPVLVPHQIIERESTPFIV
                     "
     gene            11627..13813
                     /locus_tag="TV188_000546"
     CDS             11627..13813
                     /locus_tag="TV188_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1533930.1"
                     /translation="MKTSFKQFFSFEFWQKFGKCLMVVIAVMPAAGLMVSIGNSLPML
                     NQESQLLATLGNVIAQVGWAVIGNLHLLFALAIGGSWAKERAGGAFASGLAFVLINRI
                     TGAIYGVSSAMLTDPEAKIKSLLGTEMIVKDYFTSVLESPALNTGVFVGIIAGFVGAT
                     AYNKYYNYRKLPDVLAFFNGKRFVPFVVILRSALVALVLALIWPVIQSGINGFGMWIA
                     SSQDTAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYEVMTGAAAGTKVFGQ
                     DPLWLAWVTDLVNLKGSNASTYQHLMETVVPARFKVGQMIGATGTLMGVALAMYRNVD
                     ADKKHKYKMMFISAAAAVFLTGVTEPLEYMFMFAAMPLYLVYALVQGASFAMADLVNL
                     RVHSFGNIELLTRTPMAIKAGLGMDLINFVWVSILFAVIMYVIADFMIKKMKLATAGR
                     LGNYDADILENDDTKPLSQQSIDGQSQVVQIINLLGGRENIADVDACMTRLRVTVNDP
                     SKVGSEEHWKQAGAMGLIIKGSGIQAVYGPKADILKSDIQDLLDSGAVIPEPKPAQPA
                     ASSSQQTDFKNLTEAVLAVADGEVLPITAVSDQVFAAKMMGDGFAVEPANGAIYAPVT
                     GLVTHVFPTKHAFGLLTDSGLEVLVHVGLDTVDLNGEPFTVKVSEGQRVSAGDLLAEA
                     DLTAITAAGRKTTVVVAFTNTTSIKAVNLVATGQQKAKTLVAQVEL"
     gene            13891..14712
                     /locus_tag="TV188_000547"
     CDS             13891..14712
                     /locus_tag="TV188_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEL1533931.1"
                     /translation="MTKLLTLNTHSWMEANALKKLFDLAEHILAQNYDVICLQEINQL
                     IDSEAAVPLSGYQPIAGTPAIHQDNFALLLVNYLKKRGQSYYWSWAYNHIGYDIYHEG
                     VAILSKQPIQASDILVSAVADEYDYHTRRALLAKTTIDGREAAVVSLHLSWFDQGFVG
                     EWQRLEAALQQLACPVLLLGDFNNPSGQEGYEMILKSPLDLQDSHQAADYVFGDHSIV
                     AAIDGWEDNKEAFKVDHVFTSKVFTINSSKVTFDGGEAPVVSDHYGLEVDLSWKL"
     gene            complement(15008..15466)
                     /gene="nrdI"
                     /locus_tag="TV188_000548"
     CDS             complement(15008..15466)
                     /gene="nrdI"
                     /locus_tag="TV188_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1533932.1"
                     /translation="MTDLTLVFISLSGNTLSFVRRLSQYLAEKHHIQTKAINIKELHH
                     ETFPVKESFVAILPTYLEGGNGIDSGEVEILTNPLGDFIAAHDNAKRCLGIIGSGNKN
                     FNHQYCLTAKQYAKRFGFPMLGDFELRGTSADIERLAQVIVARLTDDQQS"
     gene            complement(15862..17046)
                     /gene="sezV"
                     /locus_tag="TV188_000549"
     CDS             complement(15862..17046)
                     /gene="sezV"
                     /locus_tag="TV188_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_038674722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface antigen transcriptional activator SezV"
                     /protein_id="HEL1533933.1"
                     /translation="MDTMSLVKSLQGCLKLSITVFDKDHQVTESFWNDDTFEFYYRFQ
                     AVLRQMDKEQATNLFFQGSYNELFLIYRYQDHYILIGPWRCNVLDKTFFKVAVADKDL
                     TKEEEEILYQALKHLPVYPLNAIRDLLIVVHYFFSGKIEDLLSPPLRHYIRDFSDNIE
                     VQKANMFVKKQESKVCLYNYEKNLSSIVQEGDVHKLKEIIFSLRNTFIPVVSGDTLRS
                     EKNYSIIAFDRLAQIAIQSGMDIADAYHSREEFMRDSELATSMPDVLKIRDASLVFYT
                     QKVSELRDNRWKHVSPTVNAIIQYISVNLHKSVTTAELAQHFNMSESKLRQIFKRDTG
                     LTIYQYTSNMKIEEAKTLLRSAYAINHISDVLGFTDPSHFSKFFKKHTGESPKTYQNR
                     KH"
     gene            17296..18900
                     /locus_tag="TV188_000550"
     CDS             17296..18900
                     /locus_tag="TV188_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_156117153.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1533934.1"
                     /translation="MFLRNNKQKFSIRKLSAGAASVLVATSVLGGTTVKANSEVSRTA
                     TPRLSRDLKNRLNDIAISRDASSAQKVRNLLKGASVGDLQALLRGLDSARAAYGKDDY
                     YNLLMHLSSMLNDKPDGDRRQLSLASLLVDEIEKRIADGDSYAKLLEAKLAAIKSQQE
                     MLRERDSQLRNLEKEKEQELQKAKDERQALTESFNKTLSRSTKEYNKLKTELAKEKEK
                     AAKMTKELADKLSNAEASRDKAFAVSKDLADKLSSAEASRDKAFAVSKDLADKLAAKT
                     AEAEKLMENVGSLDRLVESAKREMAQKLAEIDQLTADKAKADAELAAANDTIASLQTE
                     LEKAKTELAVSERLIESGKREIAELQKQKDASDKALVESQANVAELEKQKAASDAKVA
                     ELEKEVEAAKAEVADLKAQLAKKEEELEAVKKEKEALEAKIEELKKAHAEELSKLKEM
                     LEKKDHANADLQAEINRLKQELADRIKSLSQGGRASQTNPGTTTAKAGQLPSTGESAN
                     PFFTIAALTVIAGAGMAVVSPKRKEN"
     gene            19123..21342
                     /locus_tag="TV188_000551"
     CDS             19123..21342
                     /locus_tag="TV188_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEL1533935.1"
                     /translation="MVKEINLSGEEVVALAAKYMTDGDVELVQKALDYATAAHFYQVR
                     KSGEPYIVHPIQVAAILADLHLDAVTVVCGFLHDVVEDTDITLEDIEFDFGKDVRDIV
                     DGVTKLGKVEYKSHEEQLAENHRKMLMAMSKDIRVILVKLADRLHNMRTLKHLRKDKQ
                     ERISRETMEIYAPLAHRLGISRIKWELEDLAFRYLNEIEFYKISHMMREKRREREALV
                     DDIVTKIKAYTTDQGLYGDVYGRPKHIYSVYRKMRDKKKRFDQIFDLIAIRCVMETQS
                     DVYAMVGYIHELWRPMPGRFKDYIAAPKTNGYQSIHTTVYGPKGPIEIQIRTKEMHQV
                     AEYGVAAHWAYKKGIRGKVNQVEQKVGMNWIKELVELQAASNGDAKGFVDSVKEDIFS
                     ERIYVFTPTGAVQELPKDSGPIDFAYAVHTQVGEKATGAKVNGRMVPLTAKLKTGDVV
                     EIVTNPNSFGPSRDWIKLVKTNKARNKIRQFFKNQDKELSINKGRELLVSYFQEQGYV
                     ANKYLERKRIEEILPKVSVKSEESLYAAVGFGDISPVSVFNKLTERERREEERAKAKA
                     EAEELVKGGEVKHENKEILKVRSENGVIIQGASGLLMRIAKCCNPVPGDVIEGYITKG
                     RGIAIHRADCNNIKSQDGYQERLIEVEWDLEHSSKDYQAEIDIYGLNRIGLLNDVLQI
                     LSNATKSISTVNAQPTKDMKFANIHVSFGIPNLAQLTAVVEKVKAVPDVYSVKRTNG"
     gene            21357..21800
                     /locus_tag="TV188_000552"
     CDS             21357..21800
                     /locus_tag="TV188_000552"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEL1533936.1"
                     /translation="MKIVIQRVKEASVSIDGKIAGAIDQGLLLLVGIGPDDQAEDIDY
                     AVRKISHMRIFSDPEGKMNRSIQDIEGSVLSISQFTLYADTKKGNRPAFTGAAKPDRA
                     SQLYNSFNAQLEQLVPVQRGVFGADMQVSLINDGPVTIILDTKYR"
     gene            complement(21927..23219)
                     /locus_tag="TV188_000553"
     CDS             complement(21927..23219)
                     /locus_tag="TV188_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL1533937.1"
                     /translation="MLTSKRLYHLGKTPLEIGTVVIGLFTMTLGAPAVKANHYKVGWA
                     WSSSSRVANHYKYEDTTKPIHSKDYQETTGLYLMVNITGVDNTNHTIVSPHYQDIRLE
                     YGKTYTTNEMIKLVQDVIDPSAESFKVISLKNAKLTKASTAEILSTDHFTTPIKGQYH
                     QKDQTYILTGQVLVEKVSKVALKDIKVTDKAGNPIQDSDAVAVTQHVKFLKKDNGQLV
                     NVDVTDSLGKEGLTGLRYYGSRVSSEELFEAAKKAFETTQAFKDGYQLVKRISTTVTQ
                     DPDITHQSHNGEIYSGASERMVYHADRDEDFNYIIDSNRIAQVYNSKYDVNNPISYAT
                     HSDSVVETYFISKDINDDYSTTYRSVTIYQQDKQQQLINEYTFKTHEAITTETIDKYL
                     KGLPNTFQAKNGTSYQFTGSLTPISETEFIAVYKDLQK"
     gene            23974..24822
                     /locus_tag="TV188_000554"
     CDS             23974..24822
                     /locus_tag="TV188_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEL1533938.1"
                     /translation="MALKDYFPDMQEGAFPLADQDWISVEVGEQYLHFPKSSLSEREQ
                     LLLGLGRQRKEPSKDQKSPWYHYLILGQGEQPEEFQGCQFIYINHQCPLAGDLIELLK
                     GIIEGVEAVLPISQTRTAFLVCHHSRSDLFQLLANLLPTIESDFGLALMIFIGNGWYQ
                     VSGNALRDYFKEENAVFTAYLAEHSASRLLTFSEVMLWSLLANSGLPALSKHFSQLLL
                     ANKEVMDLVLAMWQEHGNLVQTAQRLYIHRNSLQYKLDKFAQQSGLYLKQLDDLAFAY
                     LFILKH"
     gene            24972..26105
                     /gene="ugpC"
                     /locus_tag="TV188_000555"
     CDS             24972..26105
                     /gene="ugpC"
                     /locus_tag="TV188_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEL1533939.1"
                     /translation="MVELNLKHIYKKYPNTTHYAVEDFDLDIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELKIDGEVVNDKSPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYKKDDIDRRVKEAAEILGLTEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGSTTIYVTHDQTEAMTLADRIVIMSATKNPQGN
                     GTIGKIEQVGSPQELYNLPANKFVAGFIGSPAMNFFEVVVKDGQIISEDGLDIAIPEG
                     QAKMLEAAGYKGKKVIFGIRPEDISSNQIVHDTYPNANVTAEVLVSELLGSETMLYVK
                     LGQTEFASRVDARDFHNPGEKVSLTFNVAKGHFFDLETEQAIR"
     gene            26289..27908
                     /locus_tag="TV188_000556"
     CDS             26289..27908
                     /locus_tag="TV188_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEL1533940.1"
                     /translation="MEKHWWHKATIYQIYPRSFMDTSGNGIGDLKGITGKLDYLQELG
                     ITAIWLSPVYQSPMDDNGYDISDYQAIAAIFGDMADMDELLDEAKQRGIKIIMDLVVN
                     HTSDEHAWFVEARENPDSPKRDYYIWRDQPNNLMSIFSGSAWEYDDASGQYYLHIFSK
                     KQPDLNWENAELRQSIYDMMNFWIDKGIGGFRMDVIDLIGKIPDSEITGNGPRLHEYL
                     KEMNQASFGNHDLMTVGETWGATPEIARQYSRPENKELSMVFQFEHIGLQHKPNASKW
                     DYAAELNVPALKEIFSKWQTELKLGEGWNSLFWNNHDLPRVVSIWGNDTVYREKSAKA
                     MAILLHLMRGTPYIYQGEEIGMTNYPFERLSDVNDIESLNYAKEAMANGMSEEAVLDC
                     ICRVGRDNARTPMQWSSQKNAGFSTADQTWLPVNPNHQEINVASALADPDSVFYTYQK
                     LIQLRQTQDWLVEADYQLLETSDKVFAYKRQLGRETYLVVVNLSNQEQFFEESLHKAQ
                     VIISNTDVQAVVESQQLEPWDAFCVKLDETL"
     gene            28017..28379
                     /gene="traF"
                     /locus_tag="TV188_000557"
                     /pseudo
     CDS             28017..28379
                     /gene="traF"
                     /locus_tag="TV188_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623564.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraF"
     gene            28493..28852
                     /gene="yajC"
                     /locus_tag="TV188_000558"
     CDS             28493..28852
                     /gene="yajC"
                     /locus_tag="TV188_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEL1533941.1"
                     /translation="MGLPTILMFVVMIGLIWFMQRQQKKQAQERQNQLNAIEKGDEIV
                     TIGGMFAVVDEVDLAAKRIVLDVDGVYLPFELSAIKRVVEKGSAVTSADVDTTETAVD
                     DTAVEASDEAESAIETN"
     gene            29026..29775
                     /locus_tag="TV188_000559"
     CDS             29026..29775
                     /locus_tag="TV188_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEL1533942.1"
                     /translation="MFGLKAKSKKIVLDRIPKHIGIIMDGNGRWAKKRLKPRVFGHKA
                     GMDALQEVTIAASDLGVKVLTVYAFSTENWSRPQDEVSFIMNLPVEFFDKYVPELHKN
                     NVKVQMIGETNRLPKDTLKALEAAIAKTRQNTGLILNFALNYGGRAEITNAVGLIAQD
                     VLDAKLNPGDITEDLIANYLMTDHLPYLYRDPDLIIRTSGELRLSNFMPWQSAYSELY
                     FTPVLWPDFKRAELLKAIEDYNHRHRRFGAI"
     gene            29785..30579
                     /locus_tag="TV188_000560"
     CDS             29785..30579
                     /locus_tag="TV188_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEL1533943.1"
                     /translation="MRERFIWGGVAAAVFLPFLLIGSLPFQLFVGVLAMIGVSELLRM
                     KRLEVFSFEGVFAMLAAFVLTVPLDHYLTFLPMDASFACYGLLVFFLLAGIVISSDSY
                     GFEDASFPIAASLYVGIGFHNLVNARMTGIDKVFLALFIVWATDIGAYLIGRRFGKRK
                     LLPKISPNKTIEGSLGGIVSAVLVSFVFMLFDKAVYAPHHFGTMLILVALFSIFAQFG
                     DLVESAVKRHFGVKDSGKLIPGHGGILDRFDSMIFVFPIMHLFGLF"
     gene            30611..31876
                     /gene="rseP"
                     /locus_tag="TV188_000561"
     CDS             30611..31876
                     /gene="rseP"
                     /locus_tag="TV188_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEL1533944.1"
                     /translation="MLGIITFIIIFGILVLVHEFGHFYFAKRSGILVREFAIGMGPKL
                     FSHVDQQGTLYTIRLLPLGGYVRMAGWGDDTTEIKTGTPASLTLNDQGLVKRINLSQS
                     KLDPTSLPMNVTAYDLEDKLTITGLVLDEIKTYSVDHDATIVEEDGTEIRIAPLDVQY
                     QNASIGGRLITNFAGPMNNFILGIVVFILFAFVQGGVADYHSNHIRVVENGAAAKAGI
                     RDNDQILEINHQKINDWYELTQAVTDSAADVKAKGKLEITYQTGDQVKTIALKPEKKG
                     DQYLIGVQYPLKTSLTDKLIGGFEMAGNGALVIVTALKSLITSFSLDKLGGPVAMYQM
                     SNQAAKNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNVIEALRRKPLKQETET
                     YITLAGVAIMVVLMIAVTWNDIMRAFFQG"
     gene            32146..34002
                     /locus_tag="TV188_000562"
     CDS             32146..34002
                     /locus_tag="TV188_000562"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEL1533945.1"
                     /translation="MKQSKMLIPTLREMPSDAQVISHALMVRAGYVRQVSAGIYAYLP
                     LAHRTIEKFKTIMRQEFDKIGAVEMLAPALLTADLWRESGRYETYGEDLYKLKNRDKS
                     DFILGPTHEETFTTLVRDAVKSYKQLPLNLYQIQSKYRDEKRPRNGLLRTREFIMKDG
                     YSFHQSYDDLDVTYDAYRQAYEAIFTRAGLDFKGIIGDGGAMGGKDSQEFMAITPDRT
                     NLDRWLVLDKSIPSLADIPEEVLEEIKAELASWLVSGEDTIAYSSESSYAANLEMATS
                     EYKSSSKVTALDDLVEIETPNCKTIDEVAAFLDVAEHQVIKTLLFMVDHEPVLALLVG
                     NDQINAVKLKNHLGADFLEPASEEEARAILGAGFGSLGPVHLTDGIRIVADRKVQDLA
                     NAVAGANKDGYHLTGVNPNRDFQAEYADIREVKEGETSPDRHGVLQFARGIEIGHIFK
                     LGTRYSDSMAANILDENGRAVPIVMGCYGIGVSRILSAVIEQHARLFVSKTPKGDYRY
                     AWGINFPKELAPFDVHLITVNVKDQEAQDLTERVEASLMAKGYDVLTDDRNERVGSKF
                     SDSDLIGLPIRVTIGKKAAEGIVEIKIKATGDSIEVHADSLIETLDILTKDN"
     gene            34054..34611
                     /locus_tag="TV188_000563"
     CDS             34054..34611
                     /locus_tag="TV188_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEL1533946.1"
                     /translation="MTIEELQQLVLADHELMTILSIIETLPLKDCWLAAGAIRNAIWN
                     HLAYGIGFDPLTDVDVVFFDPEISYEAEQLLEEQLKCAYPMYQWEVRNQAYMAAHNPK
                     TPPYRSSQDAITKYPERCTAIAVRLVGGQLEVFAPYGLADISHFVCRPTPHFLEDSER
                     MDCYRQRLAKKDWHKKWPQLTYHDC"
     gene            34946..39343
                     /locus_tag="TV188_000564"
     CDS             34946..39343
                     /locus_tag="TV188_000564"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEL1533947.1"
                     /translation="MSDLFGKLMEQIEMPLEIRQSSAFSSADIIEVKVHSVSRLWEFH
                     FSFAEVLPIESYRELSDRLVRTFEAADIKVTFDIKAETINYSDQLLQAYYQEAFEHEP
                     CNGASFKSSFSRLQVRYDHHQLIIMAPDFVNNDHFRKNHLPNLAAQFERFGFGRLAID
                     MVSDQEMTDHLTKDFETNRQALVEKAVQDNIAAQQSLEAMQPPAEEAAPSPSLDYRER
                     MAQRQASFDKAVITPMIEVDTEENRIVFEGMVFDVERKTTRTGRHIINFKMTDYTSSF
                     AMQKWAKDDDELRKFDLIAKGAWLRVQGNIENNPFTKSLTMNVQQVKAIVHHERKDLM
                     PEGQKRVEFHAHTNMSTMDALPTVEDLIDTAARWGHQAVAITDHANVQSFPHGYHRAR
                     KAGIKAIFGLEANIVEDKVPISFNPVAMDLHEATYVVFDVETTGLSAMNNDLIQIAAS
                     KMFKGNIIEQFDEFINPGHPLSAFTTELTGITDNHLVGAKPIQQVLEAFQAFCQGTIL
                     VAHNASFDVGFMNANYDRYGLAKISQPVIDTLELARNLYPEYKRHGLGPLTKRFQVSL
                     EHHHMANYDAEATGRLLFIFLKEAREKHGITNLLQLNTDLVAEDSYKKARIKHATIYV
                     QNQLGLKNMFKLVSLSNVKYFEGVPRIPRTVLDQHREGLLLGTACSDGEVFDAVLTQG
                     IDAAVDLAKYYDFIEIMPPAIYQPLVVRELIKDQAGVEQIIRDLIEVGRRAEKPVLAT
                     GNVHYIEPEDAIYRDIIVRSLGQGALINRTIGRGEAAKPVPLPEAHFRTTNEMLDDFA
                     FLGQDLAYEVVVQNTQALADRIEKVEVVKDDLYTPYIDKAEETVAELTYQKAFAIYGN
                     PLPDIIDLRIEKELTSILGNGFAVIYLASQMLVNRSNERGYLVGSRGSVGSSFVATMI
                     GITEVNPMPPHYVCPSCQQSEFITDGSVGSGYDLPNKACPRCGTLYKKDGQDIPFETF
                     LGFDGDKVPDIDLNFSGDDQPNAHLDVRDIFGEEYAFRAGTVGTVAEKTAYGFVKGYE
                     RDYGKFYPDAEVDRLAAGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQFPADDVTAS
                     WQTTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPITIPADDPDVMALFSGTE
                     VLGVTPEQIGTPTGMLGIPEFGTNFVRGMVNETHPTTFAELLQLSGLSHGTDVWLGNA
                     QDLIKEGIATLKTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERSSY
                     IKAMRQNNVPDWYIESCGKIKYMFPKAHAAAYVLMALRVAYFKVHHPIMYYCAYFSIR
                     AKAFELKTMSGGLAAVKARMEDISNKRKRNEASNVENDLFTTLEIVNEMLERGFKFGK
                     LDLYKSEATEFQIEGDTLIPPFIALEGLGENVARQIVKARQDGEFLSKMELRKRGGAS
                     ATLVDKMDELGILGNMPDDNQLSLFDDFF"
     gene            39465..39893
                     /locus_tag="TV188_000565"
     CDS             39465..39893
                     /locus_tag="TV188_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1533948.1"
                     /translation="MNELDKNPALKAMVVFRKAQRTLDAQSSAFFQKANLTPTQFSVL
                     EVLYSKGSMRINKLIGSLLATSGNMTVVLKNMERNGWISRCQDAKDKRACLVQLTPEG
                     KALIETILPEHIKRVEALFSVLTETEQKQLITLLKKFKEL"
     gene            40023..40568
                     /locus_tag="TV188_000566"
     CDS             40023..40568
                     /locus_tag="TV188_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1533949.1"
                     /translation="MKQILIINGSLRTGSFNHQLAQAAEQLLEGKAAVSYLDWEQVPM
                     FSQDLEASTPESVAGVREAIQAADAIWIFSPVYNFAIPGSIKNLLDWVSRALDLSDPS
                     GPSAINGKVVTVSSVANGGHEQLFAQYQDLLPFIRTTVVGNFTKAAVNPEAWATGVLD
                     ISEETRQSLAAQAEALLEAIH"
     gene            complement(40747..41361)
                     /locus_tag="TV188_000567"
     CDS             complement(40747..41361)
                     /locus_tag="TV188_000567"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1533950.1"
                     /translation="MSAQDKLIKAQHLIDMNDIIREGNPTLRAVAKEVEFPLSDDDII
                     LGEKMMQFLKHSQDPVMGEKLGLRAGVGLAAPQIDVSKRIIAVLVPNPEDSEGNPPKE
                     AYSMEEVLYNPKIVSHSVQDAALADGEGCLSVDRVVEGYVVRHARVTVEYYDKHNEKH
                     RIKLKGYNAIVVQHEIDHINGVLFYDRINAKNPFEAKEGMLILN"
     gene            41726..43153
                     /locus_tag="TV188_000568"
     CDS             41726..43153
                     /locus_tag="TV188_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1533951.1"
                     /translation="MERLMRTQLKKLLAGTAAGTLLLFNLTCGMINAFAEQYYGWSDG
                     SSSYPSALYVTPVGDTTKKIAIPVYCFDYKFQEPLAWKEITQPSHLIVYDKYDGKNLM
                     AALVEKPNMVSYETKTKLQTLLKTKSNLITAILSRGYPNKSFFDKYKKLTDEDKRRVT
                     QCALWYHTDNISEQDLITKHLDGDSGEKSQALKELIGVVKNTSNELGEGLTFYTRYND
                     RYGPKYQNLIGSIIVPEEPQNDLEIGGGNVIDLNYQSGPMVEEGGHSGGKEEVEDTKK
                     PDVIIGGQGSVTETTEDTQKGMSGSTETQPEVEDTKQPQSDIILGGQGNVIDTTENTQ
                     EGMGGQSGDTTETEDTKQPQSDIILGGQGNVIDTTENTQEGMSGSNNGQTFEEDTRPK
                     LEFHFDNEVPNDDDAPKPEQPEQPEKPEQPRKPQQEQQSLPRPIEGNQSLPKTHEAKG
                     VLALVGVGILAMLGLGFWFRPYQKD"
     gene            43419..43688
                     /gene="rpsO"
                     /locus_tag="TV188_000569"
     CDS             43419..43688
                     /gene="rpsO"
                     /locus_tag="TV188_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEL1533952.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNNHIK
                     EHKKDHATYRGLMKKIGHRRNLLAYLRRTDVNRYRELIQSLGLRR"
BASE COUNT        12349 a         8710 c        10430 g        12323 t
ORIGIN      
        1 ttcttgtttt tttctttagg ctagctgcta gaaagcttat caattcgcgc tttattggcg
       61 gctaaggctc tttcatattt tcctgtttca tttgggttga agtaattttt cttaaccaag
      121 tgatcaggga gatattgctg cttgacccat ttttctggat atgcatgagg gtaaaggtag
      181 tgctgagcat tgcctagctc cttgctgccg gcataatgcc catcacgcag gtgtctagga
      241 atgggaagat ggccatgttg acgtaaatca gcgagagcag cgtccatagc catataggcg
      301 gaattggact ttggtgacag tgctagatca atcacaacat tggcaatgag gatacgcgcc
      361 tctgggaagc caattttctg ggcggcctca agtgcagtga cggtatggat ttgagcttct
      421 ggattggcaa gacctatgtc ctcataggcg ataatggtca agcgtctagc aagactcgga
      481 agatcgcctg cctcaataag ccttgcagca tagtgcaagc tagcattaac atcagatcct
      541 cggattgatt tttgcaaggc agatagtatg tcataatgtc cgtcgccatc tttgtccatt
      601 gtgatgtagc tgcgctgcaa agaattttca acagtattca agctgatatg acggataccc
      661 tcggtatctg gctgggttga catgacagct agatcaaggg attggtaggc ggctcggaga
      721 tctccatttg tcgctgtcgc aataaagtca aaagcagcct catctagggt cacatcaaag
      781 gcaaagcctc tctccttatc agtgatggca agcttaagcg cctgcttgat ctcctcaggt
      841 gataggggct ccagctcaaa aatctggact cgacttctga tggctggagt aaccgagaaa
      901 aaaggattcc ctgtggtagc accaatcata ataatgtgcc catgctctaa aagtggtagt
      961 aaaaagtcct gcttactctt atccaatcgg tgaatttcat caagcaaaag cacaagtcca
     1021 cctgaaaact tagcttcctc agcgatttct tggaggcgtt ttttattgtc tatggtagca
     1081 ttgaaggttc taaaggcgta cttggttgtt ccagcaatag cactagcaat tgatgtcttt
     1141 ccaataccgg gaggtccgta aagaatcatt gaggctaatc tattggcctt gaccatgcgg
     1201 tcaatgattt ttccctcccc gaccagatgc tgctggccga tgacctctgt aatggttcta
     1261 gggcgcattc tgatggctag attatcaggc attgtattcc tcccttcctt gcttttgttg
     1321 gctgtggtgc tttttaacaa cagccataaa gtttgcgatc attgtcctac cgtcagctgt
     1381 tccgatgctt tctgggtgaa attgaaggcc aaacagtggc agctgtctgt gttcaaaggc
     1441 cataatctca ttgtcctcaa agtctcttgc ggtaattaca aagtcagctg gcaggtcatc
     1501 aacaacaata gaatggtaac gcatgacggt taattgcttt ggcagctgtt gaaagagctt
     1561 agctggtgct tgtctttcaa gtatactttg cttgccatgc atgacgcgct tagcaaggcg
     1621 tagcctgcca cctagagcct cagcgatagc ttggtggcca aggcaaacgc caagcatagg
     1681 cttttggtca taaaaggccc taatcaagct aggcatctga ttggcggctt tgggccagcc
     1741 gggtccaggt gagaggacta tggcgtcagc ctgcttcgca aggtcaaata gttttggatc
     1801 ctgattggtc aatacaatcg tttgatcaaa ggcactgagg tattgggcca gattataggt
     1861 aaatgaatcg tagttatcaa ttaaaagtat cataaggtcc ttcatctagt agtgctgagg
     1921 gatcagcctg gtactattga ggcagagtgg tgtcctcaat tgttagtgag tagagtcctc
     1981 ggacagcatt gccaccaaaa atggcttcgg ccttgtctaa atctgaaagc tttagctctt
     2041 tttcctgagc cagtccctgc cttagtaatt cttgacggaa aatgcctggt agaataccgg
     2101 ctgatacagg cggtgtataa agggtctgct cgatttgcac aaaaagatta ccaatagagg
     2161 tttcaagcaa ggtcccatca gcagcaacaa agacttgctc ataaggcttg acgctcagat
     2221 gtggtcgatg actggtttta aaataagtaa agggaagctt tttgacatcg cttgattggc
     2281 gaactaatcg tgcctttaaa aagtcttttt gaagcggctc taagctttgg tctgtaaggc
     2341 taatctgccc gtccttagca atagcaatag tgagacgata ggggctgctg tcctttccct
     2401 tgagataggc ttgcaaacga tctgtcagaa gctcttcgtc ataggggtag gcaaaataac
     2461 gcgccgcctc ccttagtctg ttgaggtgct ggtctagata tattaggctt tgttgttcga
     2521 ccttggcagt ggttttgatg gtgaaatcaa tgctttgacg gttcagaaag gaagattttt
     2581 gcttgatttc ttcaaattcg tcctgccagc agctttccca ggtaatccca ccgcctaccc
     2641 cgtagatggc ctgatcgtag ctgagctgaa tcgttcgaat agcgacattg aagacacgtc
     2701 tgccatcagg caggcaaata ccaatgctgc cacagtaaac gccccttggc ttaggctcta
     2761 atcggttaat aatagccatt gtagacacct taggagctcc tgtgatggag ccacagggaa
     2821 agagtgcctg taaaatatca taaagacgac actgatcctg cagcatgccg acaatggtag
     2881 aggtcatctg ccaaacggtg gaatattgct ccaattggca gagctgtgtg actgtgacac
     2941 tcccagtttg acagatctta ttcatatcat tgcgtaataa atcaacgatc atcatgtttt
     3001 ctgaacggtt cttaggatcg gcctgtagcc agtcatgctc ttgttgatct agttctaaat
     3061 tgtaaccacg cttggttgtg cctttcatgg ggcgtgtggt gatctggttt ttctcttgct
     3121 tgaaaaataa ctcaggactg gctgaaatga cagcaaagtc atcgtgagca atgtaggcat
     3181 tgtatccagc tgcctgttca atgaccaatt gatgataaat ggccaagctg tccttagcgt
     3241 ttagcctttg gctgagctga atggtatagt tgacctgata ggtattgccc tgcctcatct
     3301 cctgatgaat ctgtgcaata gcctcttgat aggcttcctc ttgtgtagca cttgtccagc
     3361 tgtttggaat cgtcatgctg tcgtggtaga gcggaaagtc ctcgagctga cagctgtcat
     3421 gcactgtaaa ataagcaaaa tattcctgac caagtctttt attgtgtgtt gttagctttt
     3481 tgtcaaaaca ggctgctgct tcatagctga ggtagcccac aacatagtag cccagatctt
     3541 gaaattggtt gacctgctca aggacctgtc ccacctgatc aatctgctta gctactaatt
     3601 ccacgatagg agcttgaaat atatagcgtt gtcccagctc cttaaaatca ataatcgtct
     3661 ttatatgcat agcttgatta tatcataaat gcgcttttca gactgattag gagggttgaa
     3721 aagaagcctg ttagcaacca tcaacaatac aagagagcag ggcttcttga tttatgctac
     3781 aatagtagcg gatattattt agaaaaagga acaagagcat ggctaaatat ggctttttat
     3841 cagtattaga agaagagatg gacaagcatt ttcattatga ctatgctatg gattgggaca
     3901 agaaaaatca tgcggttgaa atcacccttg ttttagaggc tcaaaatcag tcagcagttg
     3961 aaaccattga tgaccaagga cagctcagca aggaagacat tgtctttgag gattatgtct
     4021 tattttacaa tccggagaaa tcacagtttc aagcagcaga ctatctggtg gctattccat
     4081 ttgagccaaa aaagggcttt tctcgtgaat ttttagccta ttttgcccag tttctcaatg
     4141 atgttgccat tgaagggcat agcgatttga tggatttctt agcagatgat agcaagcttg
     4201 attttagtct agagtggaac gaggaggcct ttgaggaagg gcaggtagga ctagaggaaa
     4261 cagagcttta tagctatccg aggtattaag atgctacatg agatgatgct gacaccaaga
     4321 ccatttgcta tgattgaggc gggtgtgaag actattgaac tacggttaaa tgatgagaaa
     4381 aggcaggcta ttaaggtagg ggattggatt tgcttttatt gtacagagga tcatagccat
     4441 attctgcaag cagaggtcgt agggttgcat tattttgatg actttgctaa gctttaccaa
     4501 gcattgcctt tagaaaaatg tggttatcgt aatgaagaat tggcactggc tcggccggag
     4561 gatatggaac agtactacag caaagagcag caagcccaat atggcgttgt tggtattgag
     4621 ctaaggctat gttgattggt gagatctagt catgaagctt ttagataaaa cagtccattt
     4681 ttctggtgca aagttagcct tgatcagtaa cggtaagatt ttgaccatct tgcgtgacgc
     4741 gataccaacg attccttacc ctaatatgtg ggatttacca ggaggtggtc gtgaaaatgc
     4801 tgaagctccc tttgattgtg cgtcacgtga gtgctatgag gagttaggtc tggcactgac
     4861 taaggacgct gtcgtttggg aaagggttta tccagggctt gttaatcctg acagccaatc
     4921 tgtctttctg gtggctctta tgaatcagga catgatagat catattgctt ttggtgatga
     4981 ggggcagggt tatcagctga tggctattga tgacttttta gcagacgatc gggtcattcc
     5041 tcagctaaag gctcgcttag ctgattattt aaggaaatag gcagacttag ctggtacact
     5101 aaacagatca gcaaacacca ctactatgtg atagctacga ccagaatcaa aaagacgatt
     5161 gacctctgcc cacatgtggc taggatcaat cgtctttgtt tttggggtgg ctaagtcttt
     5221 aatctggtag gccagatcag ctgagtagtt gatattatca atcagtcctg ctatggctta
     5281 gctgttgcta gctactgatg tgctgctagc tgtctctgac tcacctaaaa aatagctggc
     5341 tggcttatca cttactggcg tcttaccaac aagctcaggg tcaggtgcta ataggtcgtc
     5401 ctcgtcggag tcagaaacgg gcgctacaaa ttcttctagc cagcttccag tgctgccagt
     5461 gtgattagga gtttgaggct ccttaggtag tggatcacct ggtagccagg tattccctga
     5521 gtgattacta ttacctgtaa catcgttgtt ggttatttta tcaaagttga cgttataaac
     5581 aatatcctca gtgacttcct tatcatattc ctcagttgaa ataataggct tattgtaatc
     5641 acgcttgtag ccggcatctg gctgtactga tggtggtagg ataccagctg tatgtaatga
     5701 gtgtccctta cgaacaaggt aaacggcagt cttaccctta ccagctcggc taatcagctg
     5761 tccgccctct cctgccttaa aggcaacggc tacatagtgt ctcggatcgt ggaagtaata
     5821 attagggtgt ctgctaggat cctctagatc agttggcttg tcaggattaa cagcgatgta
     5881 aggtccaata taaggagcag tagttccaaa ggctgctgag aataggccag taaaggctac
     5941 cttatcgttt tcattttgtg tgatagaaaa tctcttagca aaatcagtta gattaaagtt
     6001 attggcaagg ttcactccac tgcggtattc aataaattca tagcctggat ctgggacggg
     6061 ctcagggata acaagtcctt gctccttagc ttccttccag gtaagaccac tacgaacatt
     6121 gtagaagaag cctccttgag tcacgccgtt aagcttcaat cgcccattaa agattgtggt
     6181 gaaccagaca ggaacataat tttctaagtc aaggtctgaa acatcatcac ctggcccgta
     6241 gacagccttg gtaggctgct ttctaacctt atcaaaatct acatagaagc gttgatgttc
     6301 tctgtccatc ttgccagctg ttggcaactc agcactccag cccttaaaga tacgcccctc
     6361 atgcttgatt gcctctggac gctgaatgtt caaatccttc cagtccaaat ccttacgaac
     6421 caaatagtgc acacgtttag ttttaatgcc attaacctca atgtcgccgt attcactatt
     6481 tgtactaaac aacacatgga taaagttttt gatgtttttg atgccctctg ggtgatattt
     6541 tttatagacc ccatcacgtg ttagattttc agatgaattt tccgtataga aaggaccata
     6601 aacgagctga gtttcgacct ctagattggt tgattctgtc ttgacattgc gctcaggatc
     6661 atctggcaat tctgggtcaa tcttatagat gtgagcatgg tccccatgac taatggtcat
     6721 gtagttgccc tcaattgaga tgtcctcacg acgaaccttg aagcgatcca taaattcttt
     6781 gatgagtctt tctttgcgct gttcaaaggt ttctccgtct atctttttga ggatctgttc
     6841 ttctggagtt ttaaatggct tagaaagatc aatatccttt agccagatga cgtgcgtgtg
     6901 gtcctcatga gggtattcaa agccgacctg accgtctaca ttcacctgct taatgcgtgc
     6961 ttgatctacc tttagctcct tggcgagata agctatatag gcgcgatagt ctccttcctg
     7021 aggcttggtg tggtcctttt tcttatattg ctccactaaa taagcccatt tgctacgctt
     7081 taagtcctca aagctaatag ggtgcaaatg gttcccatgc ttcaccagga ttccagtgtc
     7141 agtgacaccg ctaatgttgg tgccatcaaa taagaagcca tcactagttt tgaagtcaat
     7201 tcctgggata cccccctgct gatgaatgct aggtggtgtt gatgggaagt gaggtgtggt
     7261 tgatgcgatg tggttgatgg ttgctgatgg caggcttgat ttgaggatat agtggtaatg
     7321 atctccatga cgaacagtgt agccataggc gtcctcagca acaatgtcag ctggattaaa
     7381 gacatagccg tctccagcat gaccagttga gactactgat ccagaccttg ccgcttggtt
     7441 agaagcaggc tgtgcttcct tgtaatcctt aggaatcagg taagcccatt ttgtcccctt
     7501 caaatctgag taaaagaaga aatgcttgtg atcgccatgc ttcacaatga tacctgtatc
     7561 tgttttgcgt tcaatttgcg attcgctggt caataaaaag ccatcatcag ttgggacatc
     7621 aatcccaggg acttggtgac gttctctttt tttcgcagtc ttactgcttt tttgtttttt
     7681 ctttttcgta gccttttggt gctttttagg ctcctgagaa tgtccctttt gcgaatgcgt
     7741 ttggcaggct gttaaggcaa ggttgcaggc taacagcagt ccaacgaggg ataaaaatcg
     7801 ttgatgttgt ttcatggtta gttatcaact ccttccaaca attaacttaa ccagttaata
     7861 ttattactgg ttaagtatat catttgacat ctaagaatac aatagatttt ataaattttt
     7921 taatgaaatt aatctaatga cctaagagct gtctggaaga tgaaaggctt tttagctatt
     7981 tcaaaggctt ggagcttcaa caggcgaatc agctattggt ttttctggat ttacgagaaa
     8041 gagctgctct tttttgatgt agctggtata aaatatggta aaatagggtc tatcaagagc
     8101 ctatctacct ttagattggc tgagatttgt taggcaatgc gtccctgata aaggttgggc
     8161 ttatgggaca ataggccttg gtgctgtgtt tgtccttagt atgaaacctc tgagacggca
     8221 gagcaggatc cggttggttt aggaccgcat tagcttatct tacgataaaa aagaagcttg
     8281 aaaggaaagg ctgctttgat ctgatagagg gtcactggtt ttagggttta ggctaggggc
     8341 aagtgaccac tgatgatatg gcagcaaggg tatcgttatg aaggcatggc aagagctgac
     8401 aattacagtc catcgtgagg cagaagaagc tgtttccaat ctgctgattg aggctggcag
     8461 ccaaggagtc gctatcaatg acactgcaga ctatatcggt caagaggacc gttttgggga
     8521 gctttatcca gctgttgagc agtcagaaat ggttactatt acagcctatt atccaagctc
     8581 agctgatatt gatgacatca gacagaccat taatcagggc ttgaacaggc taaagcagtg
     8641 tgatgtggag cttggtgagt taaccctgac caatcaagaa ttggctgaag aggattgggc
     8701 ggacaactgg aaagcctatt atgagcctgc tcgtatcacg catgatttga cgatagtccc
     8761 cagttggaca gattatgaag ccacagcagg tgagaagatc attaggcttg atccgggtat
     8821 ggcatttgga acaggcacac acccaacaac taagctaagc ctgtttgcct tggagcaggt
     8881 gcttcgtggt ggtgagacag ttattgatgt ggggacaggc tcaggtgtgc tatcgattgc
     8941 tagctctctg cttggcgcca aagaggtctt tgcttatgat ttagatgatg tggcggtgcg
     9001 tgttgccaaa gacaacattg ccctcaatca agccactgac aatatccatg tagcagctgg
     9061 agacctgcta aaaggcctta ctcaagaggc agacgttatt gtcgccaata tcttggcgga
     9121 tattttggtg catgtgacag cagatgctta ccgtcttatc aagtctgagg ggtatctgat
     9181 catgtcaggg attatttcag aaaagctgga tatggtgaag caggctgctc ttaatgcagg
     9241 cttcttgcta gagactcaca tgcttcaggg cgagtggaat gctcttattt tcaaaaaaac
     9301 agatgattta tcaggagtga ttggtggctg atgcagcagt attttattaa aggcagggca
     9361 gaaaaaatcg ttcagctgac cgataaggat accattaagc atatgtttca agtgatgcgc
     9421 ttgacggata aggaagagct ggtgctagtc tttgatgacg gcattaaacg cttggcaagg
     9481 gtgtcagaca gctcagccta tgaggtggag cttatcaaag agctggaaga aaaccttgaa
     9541 atgcctgttg aggtgactat tgcctcaggc tttcccaagg gtgataagct agatgttatc
     9601 actcaaaagg cgactgagtt aggggcagca gctatttggg gctttccagc agactggtcg
     9661 gtggtcaagt gggatagcaa gaagctagct aaaaagcaag aaaaattagc taaaattgct
     9721 cttggagcag cagagcaatc caagcgtaat cgcgtaccgg agattcaact atttgaccaa
     9781 aagggtgagc tattaaagca gcttaagcag tttgataagt gctttatcgc ttatgaggaa
     9841 gcagctaagg caggtgaaag gtcgacattg gcgcgtgagc tagcaggtct tagcccaggt
     9901 caaaaagtcc tctttatctt tggaccagag ggtggtattt cttcaaaaga gctggctagc
     9961 tttaagcaag caggtgctat tactgtggga ctggggcctc gtatcatgcg gacagaaaca
    10021 gcaccgctct atgccttgag tgctgttagc tatgctctgg agctaatgtc tagctgatag
    10081 tgctaatagg agacagcacc ttgtggctca gtgcttgaca gaaaaaagag gagcatctgc
    10141 gattatgcta ataaagcacc gcttaacaaa aagatcgcta agaaggagac tgccgcaaat
    10201 caaagggcta gtctagcccg cgtaggtgca gagctgtcgg gcctttgcag cttcatttgt
    10261 aaaaaatata acaaatcatc tcaaaataaa gatactcgtc aaacggattg gtagaggagg
    10321 gacatgtggt tacgataaaa gatgtggcaa ggctagcagg agtttcgcct tcaacagctt
    10381 cgcgtgccat caatgacagt gacatgatta gtcaggcgac aaaggagcgt gtcaaaaaag
    10441 ccatggaggc cttggattat tcgcctaatt attcggcgca aaaccttgtt aagcgaaagt
    10501 ccaatactgt cgggatcatt ttgccggtgc gtgagggtca ggattcactg ggaaataacc
    10561 cttttttcat gcagattatt caaggaattg ctgctgtttg taccgatcag ggctacatgg
    10621 tagcccttgc gactggacgt agtgaggccg aattgctaaa aaacgtgcaa aacatgatcc
    10681 gtagtggcaa tattggcaag ctgatttttc tttattccaa aacagatgat caggtttttg
    10741 actttgtcaa aaggcaaaga gtggattgtg ttgtcgttgg gcaatcaacg acaaaggatc
    10801 ctggcaatgc taaatttgtc aacaacaata accatcaagc cggctatgat gcagcagcat
    10861 ttctccttca aaaaggctat gaggctattg tctatgctta tactgacatg gccgaattgg
    10921 tgcaggcaga gcgttataag ggctatgcag agctgatgac ttcaaaggct ctggcagctc
    10981 aagccctttg tgtcacgcta aaggacgata ggaaaagtca aaagcagctg ttagaccaat
    11041 tagccaagcg ctctaaagtt gcctttgtag tctgtgatga tgtgctagct attcatttgc
    11101 agcgtctcat caagcaagta gcagctgaca cccagctagc aatcgttagc ttcaataatt
    11161 ctgtcctagc ggagcttgcg agtcctgcct tgacctccat tgctattttt ccctatcagc
    11221 tgggagagca agctgctgag ctggtcttat caagcgcagc gccatcacca cagccagtct
    11281 tagttcctca tcagatcatt gaaagagagt ctacgccttt tattgtttga tttaccgtta
    11341 agcctattcc taagcaaagt actgatagct tgcttaggaa taaggctttt tatttaggaa
    11401 tttattttgt ttgctaatag tattaaagag aagcaacgtt tactttagca ttttcattga
    11461 aatcttctta agaaaacgct ttacaaaaca aaaaaaggtt ggtaaaataa gcttatcaaa
    11521 agcgcaaacg tttgcgttga atgtgcttgt ttttaaaaag gaattgagag ttcatcagct
    11581 tttagctggt tattcttgat tcctagtcca aaaaaggaga ggtcgaatga aaacatcatt
    11641 caaacaattt tttagcttcg agttttggca aaaattcggg aaatgcttga tggttgtcat
    11701 tgctgttatg cctgctgcag gtttaatggt gagtattgga aattctctgc ccatgcttaa
    11761 tcaggagtcg cagcttttag cgacgcttgg taatgtcatt gctcaggttg gttgggcagt
    11821 tattggtaac cttcatttgc tttttgccct tgctattggt ggcagctggg ctaaggagcg
    11881 tgctggcggt gcctttgctt cagggcttgc ttttgttttg attaaccgta ttacaggggc
    11941 tatctatggc gtttcttcag ccatgctgac tgatccagag gccaagatta aaagtctttt
    12001 gggcactgag atgattgtca aggactactt tacaagcgtc ttagagtcac ctgctctaaa
    12061 taccggtgtc tttgttggga ttatcgctgg ctttgtgggt gcaacagcct ataacaaata
    12121 ctacaattac cgtaagctgc ctgatgtgct ggctttcttt aatgggaaac gctttgttcc
    12181 ttttgtagtt atccttcgtt cagctcttgt ggccctagta ttagccttga tttggccagt
    12241 tattcagtct ggtattaatg gctttggcat gtggattgcc tcatctcagg acacagctcc
    12301 aatccttgcg ccattcttat atggaacatt ggagcgtctc ttgctgccat ttggccttca
    12361 ccacatgcta acgattccga tgaactatac agctcttggg ggcacctatg aggtcatgac
    12421 aggagcagct gctggaacta aggtatttgg tcaagaccct ctttggctag cctgggttac
    12481 tgaccttgtt aatctcaagg gctctaatgc gtcaacctat cagcatttga tggagactgt
    12541 tgttccggct cgttttaagg ttgggcaaat gattggtgca acaggaacgc ttatgggggt
    12601 tgccctagca atgtaccgta atgttgatgc ggacaaaaag cataaataca aaatgatgtt
    12661 tatctcagca gcggcagcgg tatttttgac aggggtcact gagccactgg aatacatgtt
    12721 tatgtttgct gcgatgccat tatatcttgt ctatgccctt gttcaaggag cttcctttgc
    12781 aatggctgat ttggtcaacc ttcgtgtgca ttcctttggt aatatcgagc tattgacccg
    12841 aacgcctatg gcgattaagg ctgggcttgg tatggatttg attaattttg tctgggtgtc
    12901 tattctgttt gctgtgatca tgtatgtcat tgctgacttt atgattaaaa aaatgaagct
    12961 agcaacagca ggtcgcctag ggaattacga tgctgatata ctagaaaacg atgatacaaa
    13021 gcctttgtca cagcagtcta ttgatggtca gtcacaggtc gtccaaatca ttaatctcct
    13081 gggtggacgt gagaatattg ctgatgtaga tgcttgtatg actcgcttgc gtgtaacagt
    13141 caatgaccca agcaaggttg gcagtgagga gcattggaag caggcgggtg ctatggggct
    13201 aatcatcaag ggcagtggta ttcaggctgt ctatgggcca aaggctgata ttttaaaatc
    13261 agatatccaa gacctgctag actctggtgc agtcattcca gagccgaagc ctgctcagcc
    13321 tgctgcctca tcatcacagc agacggactt taaaaaccta acagaggctg ttttggcagt
    13381 agcagatgga gaagtcttgc caatcacagc agtttctgat caggtctttg cagctaaaat
    13441 gatgggagat ggctttgctg ttgagccggc aaatggcgct atctatgcgc cggtaacagg
    13501 tctggtaacc catgtctttc caaccaaaca tgcctttggc ttgctgacag atagcggcct
    13561 agaggtgctg gttcacgttg gtcttgatac cgttgacttg aatggtgagc ccttcactgt
    13621 caaggttagt gagggtcagc gcgtatcggc aggagatctc ttggctgagg ctgacctaac
    13681 tgcgattaca gcagcaggac gcaagacaac ggttgttgtc gcctttacca atactacaag
    13741 catcaaagct gttaaccttg ttgcgactgg tcaacaaaaa gcgaagaccc tcgttgcaca
    13801 ggtagagctt taagaataac caaagagagt ggtagatagc agtatgtcag acctgcaggc
    13861 tgccacttct cttgtcgtat aggagaagat atgaccaagc tcttaaccct taacacacat
    13921 tcttggatgg aagccaatgc cttaaaaaag ctgttcgact tggcagagca tattttggct
    13981 cagaactatg acgtgatttg cctacaagaa atcaatcagc tgattgacag cgaagcagca
    14041 gtgccattat caggctacca gccaattgca gggacacctg ccattcatca ggataacttt
    14101 gccctcttgc ttgtcaatta cttaaaaaaa cgtggccaaa gctactactg gtcgtgggcc
    14161 tacaatcata ttggctatga tatttaccat gagggtgttg cgatcttatc caagcagccg
    14221 atccaagcct cagacatttt agtctcagcg gtggctgacg agtatgatta ccacaccaga
    14281 cgggctttac tggccaaaac aaccattgat ggcagggagg cagcagttgt gagcctgcat
    14341 ttgtcttggt ttgatcaggg ctttgtcgga gaatggcagc gattagaggc agccctgcag
    14401 cagctagcct gtcctgtgct attgctggga gattttaaca atccaagtgg ccaagagggc
    14461 tatgagatga ttctaaaaag ccccttagac cttcaggata gtcatcaggc tgcagactac
    14521 gtctttggag accatagtat tgttgctgct attgatggct gggaggataa caaagaggcc
    14581 tttaaggtcg accatgtctt taccagtaag gtctttacca ttaacagctc aaaggtgacc
    14641 tttgatggtg gtgaagcacc ggttgtcagc gaccattatg gcctagaggt tgacctcagc
    14701 tggaagctgt aacaaaaaaa gccagcagga cttgatagac tgctgacact gtaagaaaca
    14761 gatggttatc ttagctctta gaagtaagct tatcgcaagg cttctaagag cttttttgca
    14821 tttatatttc atgagcatat gagaaagttg cagacaaatg ctggacacat aatcagactg
    14881 tgggctagtt acatcgtctg ctctgatttg tgtcagatag tgatgatctg tgctgccttg
    14941 tgattggcca gatatttacc tcatatcaat agcagaaagt caagtctccc tcagcctatc
    15001 tcctagctta cgattgctga tcatcagtca gtctagctac aattacctgt gccaagcgct
    15061 caatatcagc actggtcccg cgtagttcga aatctcccag cattggaaag ccaaagcgct
    15121 tagcatactg cttggctgtt agacaatact ggtgattgaa gtttttgttg ccagagccga
    15181 taatccctaa acaacgcttg gcattatcat gcgccgcgat aaagtctccc agcggattgg
    15241 tcaagatttc aacctcccct gagtcaatcc cgtttcctcc ttcaagatag gtcggcaaaa
    15301 tagcaacaaa gctctccttg actggaaagg tttcgtgatg aagctccttg atattgattg
    15361 ctttagtctg tatgtggtgc ttttctgcca ggtattgcga caagcgccta acaaagctca
    15421 gggtattgcc gctaagactg ataaaaacaa gggtcaagtc tgtcataaaa gactccttta
    15481 gcaagattag tttcctaacc agcttagcac aatacccctg aatacacaac tcatatgaca
    15541 atgctctgca cgacaaacgc gcgaaacagt catttccgaa tgatagtata gacttaagca
    15601 gatacattca ccgttttttc tatagtaaaa gctatagaaa ataagatatc ttcttgaaat
    15661 agctaaacat tgacatacag aaagctttgt tttcttgcta aaaccctatc atgcgtctgc
    15721 cgtgcaatgc tctgacagct agcccactag tcacatcaca taaaaaaggc ttggtgacaa
    15781 ggacggtaag tccaaatcat caagtctttt tatggagaga gcttagtgtt agctgttacc
    15841 cgaatcaaga ggcccttgct gctaatgctt gcgattttga taggtctttg ggctttctcc
    15901 ggtatgcttt ttgaaaaatt tagaaaaatg tgagggatca gtgaagccca acacgtctga
    15961 aatgtgatta atggcataag cagagcgcag caatgtctta gcctcttcaa ttttcatgtt
    16021 tgaggtgtat tggtagatgg tcaagcctgt atcacgctta aagatctgtc tcagcttgga
    16081 ctcgctcatg ttaaaatgct gtgccagctc agcggttgtg acactcttat gcaggttgac
    16141 actgatatat tggataatgg cattaaccgt aggagagaca tgtttccagc ggttgtcccg
    16201 cagctcactc accttttggg tgtaaaagac cagtgaggca tcacgaattt tgagcacatc
    16261 tggcattgag gttgccagct cgctgtctct catgaactcc tctcgtgaat ggtaggcatc
    16321 agcaatatcc ataccagatt gaatggcaat ctgggctagt cgatcaaagg caatgataga
    16381 ataatttttt tcagagcgca gcgtatcacc actcaccaca gggataaagg tatttcgtag
    16441 actgaagatg atttccttga gcttgtgcac atcaccctct tgaacaatgc tagataaatt
    16501 tttctcataa ttgtagagac aaaccttaga ttcctgcttc ttgacaaaca tattggcctt
    16561 ttgcacctcg atattgtcgg aaaaatccct aatatagtga cgtaaaggag gtgataacaa
    16621 atcctctatc ttgccggaaa agaagtaatg gaccacaatc aagaggtcac gaatagcatt
    16681 caaaggataa acaggtaaat gctttagcgc ttggtaaaga atctcttctt cttccttagt
    16741 caaatcctta tcagcaacgg ccaccttaaa aaaggtctta tccaaaacat tacagcgcca
    16801 agggccaatt aaaatataat gatcctgata acggtatatt aaaaaaagct cattatagct
    16861 tccctgaaag aaaagattgg ttgcctgttc cttgtccatt tgcctaagca ctgcttgaaa
    16921 acgataataa aattcaaagg tatcatcatt ccaaaagctt tctgtcacct gatggtcctt
    16981 atcaaatact gtaattgata acttcaaaca gccctgtaga gattttacta acgacatagt
    17041 atccatgcta agcgtcaccc ccttcataat cctcacggta tcttattcta tcttaaaatt
    17101 taagaaaagc aaggatatgc acttataatg aaaaaataga cataaaaaac aataatatac
    17161 attcttgctt attaaataaa aatgacaatg tactgcataa agaagttcct gtcattaaaa
    17221 taaaagtgcc atgaggttat aatagtatgg taaaacaaaa aagtgtgccc ataacgggta
    17281 gagaggaatt gacatatgtt tttgagaaat aacaagcaaa aatttagcat cagaaaacta
    17341 agtgccggtg cagcatcagt attagttgca acaagtgtgt tgggagggac aactgtaaaa
    17401 gcgaactctg aggttagtcg tacggcgact ccaagattat cgcgtgattt aaaaaataga
    17461 ttaaacgata tagccataag tagagatgcc tcatcagccc aaaaagttcg aaatcttcta
    17521 aaaggcgcct ctgttgggga tttacaggca ttattgagag gtcttgattc agcaagggct
    17581 gcgtatggta aagatgatta ttacaattta ttgatgcacc tttcatcgat gttaaatgat
    17641 aaacctgatg gggatagaag acaattaagt ttggcttcat tacttgtaga tgaaattgaa
    17701 aagcggattg ctgatggaga tagttatgca aaacttcttg aggctaaact tgcagctatt
    17761 aaatctcaac aagaaatgct tagagaaaga gattcccaac ttcgaaatct agagaaggaa
    17821 aaagaacaag aactacaaaa agctaaagat gagcgtcaag ctcttaccga atcattcaac
    17881 aaaactttat caagatcaac aaaagagtat aataaactaa aaacagaact tgcaaaagaa
    17941 aaagaaaaag cagctaagat gactaaggaa ttagcagata agctaagcaa tgctgaagca
    18001 agtcgtgata aagcctttgc agtatcaaaa gatttagcag ataaactaag tagtgctgaa
    18061 gcaagtcgtg ataaagcttt tgcagtatca aaagatttag cagataaatt ggcagctaaa
    18121 acagcagaag ctgaaaagtt aatggaaaac gttggtagtc tagaccgctt ggtagagtct
    18181 gcaaaacgtg aaatggctca aaaattagca gaaattgatc aattaactgc tgataaggct
    18241 aaggctgatg cagagcttgc agctgcaaat gacaccattg catcacttca aacagagcta
    18301 gaaaaagcta agacagagct tgctgtttca gagcgtttga ttgaatcagg caaacgtgaa
    18361 attgctgagc tacaaaaaca aaaagatgct tctgataagg ctttagtaga atcacaagct
    18421 aatgtagcag agcttgaaaa acaaaaagca gcatcagatg ctaaggtagc agagcttgaa
    18481 aaagaagttg aagctgctaa agctgaggtt gcagatctta aagcacaatt agctaagaaa
    18541 gaagaagagc ttgaagccgt taagaaggaa aaagaagcgc ttgaagctaa gattgaagag
    18601 ctcaaaaaag ctcatgctga ggaactttca aaacttaaag aaatgcttga gaagaaagac
    18661 catgcaaatg cagatcttca agcagaaatc aatcgcttga agcaagagct agctgacagg
    18721 attaagtcat tgtcacaagg tggtcgtgct tcacaaacaa acccaggcac tacaactgct
    18781 aaagcaggtc aattgccatc tactggtgag tctgctaacc cattcttcac tattgcagct
    18841 cttactgtca tcgctggtgc tggtatggct gtggtgtctc ctaaacgcaa agaaaactaa
    18901 gctatttcct ctttccccaa tggacaatag ccgaaataat agagcgacta tcgttctaac
    18961 acaaaagcaa cagtctcctg tctgttgctt tttgtgatat tagggctcat cagtctaggc
    19021 taatggtttt ctgcgcttta tctgcagctt tgaggattcc ttcttttgct tttacagtga
    19081 aagtgttaaa ataggaaaaa caactagtaa ttgaggaagt aaatggttaa agaaatcaat
    19141 ttatcaggag aggaagtagt tgcccttgct gccaagtaca tgacagacgg tgacgtcgag
    19201 cttgtgcaaa aggcgcttga ttatgcgaca gctgctcatt tttaccaggt tagaaagtcg
    19261 ggggagcctt atattgtgca ccctattcag gtagcagcaa tcctagcaga cctgcatttg
    19321 gacgctgtga cagttgtctg tggctttttg catgatgtgg tagaggatac tgatattact
    19381 ctagaggaca ttgagtttga ctttggtaag gacgttcgtg acattgttga tggggtcaca
    19441 aagcttggta aggtagaata caagtctcac gaggagcagc tggctgaaaa ccaccgcaaa
    19501 atgctcatgg ccatgtcaaa ggacattcgt gtgattttgg tcaagctagc cgaccgactg
    19561 cacaatatgc gcaccctcaa gcacctccgt aaggacaagc aggagcggat ttctcgtgaa
    19621 accatggaaa tctatgcccc gctagcccat cgcttgggga tcagtcggat caagtgggag
    19681 ctggaggatc tagcttttcg ctacctcaat gagatcgaat tctacaaaat ctctcatatg
    19741 atgagagaaa agcggcggga gcgcgaagct ttggttgatg atattgtcac taagattaaa
    19801 gcctacacca ccgatcaagg gctttatggt gatgtctatg gccgtcctaa gcacatctac
    19861 tcggtttacc ggaaaatgcg tgacaagaaa aagcgctttg atcagatatt tgacttgatt
    19921 gcgatccgtt gtgtcatgga gacacaaagt gatgtttacg cgatggtcgg ctatattcat
    19981 gagctctggc gtcccatgcc tggccgcttc aaggactaca ttgcagcgcc taagaccaat
    20041 ggctatcagt cgattcacac gactgtttac gggccaaaag gaccgattga aattcagatt
    20101 cggaccaagg aaatgcatca ggtcgctgag tatggggtag cagcccactg ggcctacaaa
    20161 aaaggtattc gtggcaaggt caatcaagtc gagcaaaagg ttggtatgaa ttggattaag
    20221 gagcttgtcg agcttcaggc tgcctcaaat ggcgatgcta agggctttgt tgactcggtg
    20281 aaggaggaca tcttttcaga gcgtatctat gtgttcacac cgacaggagc agtgcaggaa
    20341 ttgcccaagg attcaggccc tatagacttt gcctatgccg ttcacactca ggttggtgaa
    20401 aaggcgacag gagccaaggt caatggccgc atggtgccct tgacagccaa gttaaaaacc
    20461 ggtgatgtgg tggaaattgt caccaatccg aattcctttg gtcctagtcg tgactggatt
    20521 aagctcgtca agaccaataa ggctcgtaac aagattcgcc aattctttaa aaatcaggac
    20581 aaggagctgt ctatcaataa aggacgtgag cttctggtta gttattttca agagcagggc
    20641 tatgttgcca acaagtacct tgagcgtaag cgtattgagg agattttacc aaaggtcagt
    20701 gttaaaagcg aggagtctct ctatgccgct gttggctttg gcgatattag cccagtcagt
    20761 gtctttaata aattaaccga aagagaaagg cgtgaggagg agcgtgccaa ggctaaggct
    20821 gaagctgagg agctggttaa gggcggtgag gtcaagcatg aaaacaaaga gattctcaag
    20881 gtccgcagtg aaaatggcgt gattatccaa ggggcgtctg ggcttctcat gcgtatcgcc
    20941 aaatgctgca atcccgtacc aggagatgtg attgaaggct atattaccaa gggacgaggc
    21001 attgctattc accgcgcaga ctgtaataac atcaagagtc aggacggcta tcaggagcgt
    21061 ctcattgagg ttgagtggga tttggagcat tctagcaagg attaccaagc tgagattgat
    21121 atttatggtt taaatcgtat cggcctgctc aatgatgtcc tgcaaatcct atctaacgcc
    21181 accaagagca tttcaactgt caatgcccag ccgaccaagg acatgaagtt tgccaatatt
    21241 catgtgagct ttggcattcc taatctggct cagctgacag ctgttgttga aaaggtcaag
    21301 gcggttccag atgtttacag cgtcaaacga accaacggat aaaaaggaga ccaaccatga
    21361 aaattgtgat tcagcgcgtc aaggaagcct cagtgtcgat tgatgggaaa atagctggcg
    21421 ctattgatca agggctgctg ctgcttgttg gcataggtcc agatgatcag gcagaggata
    21481 tagactatgc agtgcgtaaa atcagtcata tgcggatttt ttcagacccc gagggcaaga
    21541 tgaaccgatc cattcaggac attgagggca gtgtcttgtc tatctcgcag tttacgctat
    21601 atgctgacac caaaaagggc aaccgacctg ccttcaccgg ggctgctaag cctgacaggg
    21661 ccagccagct ttataacagc ttcaacgctc agctagagca gcttgtaccg gttcagcgag
    21721 gggtctttgg tgcggacatg caggttagtc tgatcaatga tggcccagtt acgattatcc
    21781 tagatacgaa gtatcgataa ctgcctagcg atcgatcgtt tgcttaggag agtcatataa
    21841 aggaaaaaca aaaagacgag tggtatgaga agcactcgtc tttgtcgttt atgctgctgt
    21901 gttgaagcta gctagggcta ctagtcttat ttttgcaggt ctttgtagac tgcgatgaat
    21961 tctgtctcag aaattggggt taagctgcca gtgaattggt aagaagtacc atttttagct
    22021 tggaaagtat taggtaaacc tttaaggtat ttgtcgatag tctcagtggt aattgcttcg
    22081 tgtgttttaa aggtgtattc gttaatcagc tgctgctgtt tgtcctgttg gtaaatagta
    22141 actgaacgat aggttgtgct atagtcatcg ttaatatcct tagaaataaa ataggtttct
    22201 acaacagaat ctgaatgtgt cgcatagcta atgggattgt tgacgtcata ctttgaatta
    22261 tatacttgag ctatcctgtt agaatctatg atatagttaa agtcctcatc gcgatcagca
    22321 tggtagacca tgcgttcact agctccactg taaatctcac cgttatggct ttgatgagtt
    22381 atatcaggat cctgcgtgac tgttgtactg attcgcttga cgagctgata cccgtctttg
    22441 aaagcctgag tggtttcaaa agccttttta gcagcttcaa agagctcctc agaagagacc
    22501 ctgctgccat agtatcttaa cccggtaagt ccttctttac caaggctgtc agttacatca
    22561 acattaacaa gctgcccatt gtcttttttg aggaatttaa cgtgctgtgt cacagctacg
    22621 gcatctgaat cttggattgg gtttcctgcc ttatctgtta ccttaatgtc cttgagagct
    22681 accttgctaa ctttttccac aaggacctga cccgtcaaga tgtatgtttg gtctttttga
    22741 tgatactgtc ctttgattgg tgtcgtaaaa tggtctgtgc taagtatttc agctgtagaa
    22801 gcttttgtta atttggcatt tttcaaacta atgaccttaa agctttctgc tgaaggatct
    22861 atgacgtctt gaactagctt tatcatctca tttgtggtgt aggttttgcc atattctagt
    22921 ctaatatcct gataatgtgg agatacgatg gtgtgattag tgttatctac tccagtgata
    22981 ttgaccatga ggtacagtcc tgtggtttct tgatagtctt ttgaatggat tggcttagtg
    23041 gtgtcctcgt atttatagtg atttgctacc ctactagagc ttgaccatgc ccacccaact
    23101 ttgtaatggt ttgctttaac ggcaggtgct cccaaggtca tggtgaatag tccaatgact
    23161 acagttccta tttctaaagg tgttttccca aggtgataca gtctttttga agtcaacata
    23221 tttcaaacct ccctaaatcc tgtcagtctc tatagttata aaaatacaga gaatcgttag
    23281 aagaattaat gtttcatgcc ggcaagatga gtgtaacaaa agattggtgc cgatacaaga
    23341 agatggagat tagagcatct ggtttcaatg agagttacat aatagcagaa ggttttttca
    23401 ctatgagagc taatcgtctt aaaatggtat aatagcaagt gaataggcta tctaactggt
    23461 ttaacagcca tttttagaga agcttaatag tattgctgat aagtgactcg tatctccata
    23521 ttgcttttca aaggctatgt tagctatgat aagcgtgacc aggctatcgg aaaatccagt
    23581 gttcttaaag gctttgaagc tctggctttg aaccttagct ctggtgtttc tatgaaaatg
    23641 acttgggcct tgtaccagat aagaatgaag tcaaattgag gttttttgac aaaatgtttg
    23701 agtaaataca agttcataga agtctaatgt ataaaaatac aattgtatcg ccataatctg
    23761 aatgaccaaa ccattaaaaa aataaaattt ttaaacattt tggaaaacgc tttcaaaact
    23821 aaaaagaact gtcctatagt cattgcttag cattaaagca aggtgtgaaa tgttatcata
    23881 tggagaaata ggctgtcttg tgctgtatct gtgccaaaaa agaatgcttg tttttgtgat
    23941 ataatgtgac taagaaacct gaaaggaatg cttatggcat taaaagacta ttttcctgat
    24001 atgcaagagg gtgcatttcc tctggctgac caagattgga ttagcgttga ggttggggag
    24061 cagtacctcc atttccccaa atccagcttg tcagagcgag agcagctttt gcttggtttg
    24121 gggcggcagc gcaaagagcc gtccaaggat cagaaatctc cttggtatca ttatttgatt
    24181 ctgggccaag gggagcagcc ggaggagttt cagggttgcc agttcatcta tatcaaccat
    24241 caatgtcctt tagcaggtga tttgattgag cttctaaagg ggatcataga gggagttgag
    24301 gctgttttgc ccattagcca gaccaggaca gcttttttgg tctgtcacca tagccgttca
    24361 gacctttttc agctcttagc aaatttattg cccacgattg agagcgattt tggtttggcc
    24421 ttgatgattt ttatcggtaa tggctggtat caggtgtcag gaaatgcctt gagagactat
    24481 tttaaggaag aaaatgctgt gtttacagct tatcttgctg agcactctgc cagtcgcttg
    24541 ctgacctttt cagaggtcat gctctggtca ctcttagcaa acagtggttt gccagccttg
    24601 tcaaagcatt ttagtcagct gcttttagcc aataaagagg tcatggatct ggtgctcgcc
    24661 atgtggcagg agcatggcaa cctggtacag acagcccagc gcttgtatat tcatcgcaat
    24721 tcgctgcaat ataagctgga taagtttgct cagcagtcag gtctctattt aaagcagcta
    24781 gatgacttgg cctttgctta tctatttata ctgaagcatt agatttgtgc agggtgccca
    24841 aagacatttg ggcgttttgt ctatatgatg aaaacgctat ctttgctata ataaaagcat
    24901 caaataaaaa gtgtcagggt tgctagcatt gcagtcagct agcagcctat ctgacccatt
    24961 aggagtaacg catggttgaa ttaaacttaa agcacatcta taagaaatac ccaaatacca
    25021 cacactatgc tgttgaggat ttcgatttag acattaagga taaggaattt atcgtttttg
    25081 tagggccttc aggctgtggt aagtcaacaa cgcttcgtat gattgctggg cttgaggata
    25141 tttcagaggg tgaattgaaa attgacggtg aggttgtgaa tgacaaatca ccaaaggacc
    25201 gcgatatcgc gatggttttc caaaactatg ccctttaccc gcatatgacc gtttatgaca
    25261 acatggcctt tggtctcaag ctacgtaaat acaaaaaaga tgatattgat cgtcgtgtca
    25321 aggaagcagc agaaatcctt ggcttgacag aatttttaga acgtaagcca gcagaccttt
    25381 ctggtggtca gcgtcagcgt gtggctatgg gacgtgctat cgtgcgtgat gccaaggtat
    25441 tcttgatgga cgagcctttg tcaaacctag acgctaagct gcgggtgtca atgcgtgctg
    25501 aaattgcgaa aattcaccgc cgtatcggct caacaacaat ctacgtaacg cacgaccaga
    25561 ccgaagcgat gaccttggca gatcgtatcg ttatcatgag tgccactaaa aaccctcaag
    25621 gcaacggtac aatcggaaag attgagcagg ttggctcacc acaggagctc tataacctac
    25681 cggccaataa atttgttgca ggctttattg gaagccctgc gatgaacttc tttgaggtgg
    25741 ttgtcaagga cggtcagatc atcagtgagg acgggcttga tattgctatt ccagaaggtc
    25801 aggctaaaat gcttgaagca gctggctata agggcaagaa ggttattttt ggtatccgtc
    25861 cagaagatat ttcaagcaac caaatcgtgc atgacaccta tccaaatgcc aatgtcacag
    25921 cagaggtctt ggtttctgag ctgcttggat ctgaaaccat gctttatgtt aagcttggtc
    25981 aaacagagtt tgcttcacga gttgatgcgc gtgacttcca caatccaggt gaaaaggtta
    26041 gcttgacctt caatgttgct aaggggcatt tctttgatct agaaacagag caagctattc
    26101 gctaataaca cctcctagaa taaaatcctc atcttgcttg aggatttttt aacaaaagaa
    26161 aatgcaagcg attgcgctat caaaaagaaa aagggattta tcataaagac aacagatgtt
    26221 ctgtagtgct aggcgatcat aatgatggca cgaaatagca ggagactgtt tagtaataag
    26281 gagatatgat ggaaaaacac tggtggcata aagcgacaat ttatcaaatt tacccaaggt
    26341 ccttcatgga tacaagtggg aatggtattg gtgatttaaa aggaatcaca ggtaagctgg
    26401 attatctaca ggagctaggg atcacagcta tttggctgtc tccagtttat caatcaccaa
    26461 tggacgataa cggctatgat atttcagact atcaggccat tgcagctatt tttggtgata
    26521 tggctgatat ggacgagctg cttgatgagg ccaagcagcg ggggatcaaa atcatcatgg
    26581 atttggttgt caatcacacc tctgatgagc acgcttggtt tgtggaggca agagaaaatc
    26641 ctgacagtcc taaacgagat tattacattt ggcgtgatca gcctaataat ctcatgtcga
    26701 tcttttctgg ctctgcttgg gaatatgatg atgcctctgg gcagtattat ctgcacatat
    26761 tcagtaaaaa acagcccgac ttgaattggg aaaatgctga attgcgtcaa agcatttatg
    26821 acatgatgaa tttctggatt gataagggga taggtggctt tcgcatggac gtcattgacc
    26881 tgattggtaa gattccggat tctgaaatta caggcaatgg cccaaggctg catgaatacc
    26941 tcaaggagat gaaccaggca agctttggga atcatgacct gatgactgtt ggtgaaacat
    27001 ggggcgctac accggaaatt gctcgtcagt attcacgtcc tgaaaataag gagctgtcaa
    27061 tggtctttca atttgaacat atcggcttgc agcataagcc aaatgcttct aaatgggatt
    27121 acgcagctga gttgaatgtt ccggctctca aggagatttt tagcaagtgg cagacagagc
    27181 taaagctagg tgaaggctgg aactcccttt tttggaacaa tcatgacttg cctcgtgtcg
    27241 tctccatttg gggaaatgat acagtatata gagagaagtc tgccaaggca atggctattt
    27301 tgctgcattt aatgcgtggg acaccttata tttatcaggg tgaagagatt ggcatgacca
    27361 attacccctt tgagcgcttg agtgatgtga atgatattga atcactgaat tatgccaagg
    27421 aggctatggc taatggcatg tcagaggagg ctgttcttga ttgtatttgt agggtgggtc
    27481 gagacaatgc aagaacacca atgcaatgga gcagtcaaaa gaacgccggc ttttcaactg
    27541 ctgatcagac ctggctgcct gtcaacccaa atcatcaaga gattaatgtg gctagtgctc
    27601 tagctgatcc tgattctgtt ttttacacct atcaaaagct tattcagctg cgtcagacac
    27661 aggattggct ggtggaggca gattatcagc tgctggaaac atcagataag gtttttgcct
    27721 ataagcgtca gcttggtaga gagacttacc ttgttgttgt caatctgtct aatcaagagc
    27781 agttttttga agaaagtctt cataaggccc aagtgattat cagcaatacc gatgtgcagg
    27841 cagtcgtaga aagtcaacag ctggagcctt gggacgcctt ttgtgttaag cttgatgaga
    27901 ccttgtagcc tagctgcttg ctgtgcctca gctcaataat cgtagcgatt ctttgagaat
    27961 tttgacaaat tgctgtatga ttagtagaag aattagatac aaaagaggag gctgagatga
    28021 ccgttgaaga aaccatgacc tttgcaaaaa gcattgcagc atttagatag gtagagatta
    28081 gtgaggtagt cactaggcta gcagcaggtg aggacatcac cgtcttttta ggcagagcga
    28141 cctgtcctta ttgtcgtcgc tttgcaccca agctagcaag cgtagcaagg caggagcata
    28201 aggatatttt ctttgtagat agtgaagact caacagagct tgcagacctg caggcctttc
    28261 gtgagcgcta tgggcttgct actgtgcctg ccctgctcat tagtcgtcat caggaggtca
    28321 aggcagtctg tgattctagc ttgactgagg aagccatttt ggctttccta gagcagtgac
    28381 agacagctaa ttatctggtg caagtaatag aaatgtaatc agtcatgtct tgctatgtga
    28441 gtccaaatct gctatagtag gacatgactt ttagacgaaa taaggagata ttatgggctt
    28501 accaacaatt ttaatgtttg ttgtcatgat tggtttaatt tggtttatgc agcgtcagca
    28561 aaaaaagcag gcgcaggagc gccaaaatca gcttaatgcg attgaaaaag gcgatgagat
    28621 tgtgacgatt ggtggcatgt ttgcagtggt cgatgaggtt gatttagcag caaagcgaat
    28681 tgtcttagat gttgatggtg tctatctgcc atttgagcta tcagcgatca agcgcgtggt
    28741 cgaaaaagga agtgcagtga catcagctga tgtggatacg acagagactg cagttgatga
    28801 cacagcggtt gaggcttcag acgaagctga atcagctatt gagacaaatt aagaaaatga
    28861 ggtctgaagc attagtgttt cagacttttt taggtgatga tagcaggtag ccagacagag
    28921 ctgtcatgtg ctatggaaat atcgtctaca acgagaaaaa gcgagccaaa ccgcatgaaa
    28981 tatggtaaaa tatgaggtaa gtatgcttgt gaataaggaa aaaacatgtt tggattaaaa
    29041 gcgaagtcaa aaaaaatcgt tttggatagg attccaaagc acattgggat catcatggat
    29101 ggtaatggac gctgggcgaa aaaacgctta aagccgcgtg tctttggaca taaggcgggt
    29161 atggacgctt tgcaggaggt aacgattgca gcttcagatt taggggttaa ggtgttaaca
    29221 gtctatgcct tttcgacaga aaattggtca agaccacaag atgaggtgag cttcattatg
    29281 aacctgcctg ttgagttttt tgataagtat gtgcctgagc tgcacaaaaa taatgtcaag
    29341 gtgcagatga tcggtgagac caaccgccta cctaaggata cactaaaggc cttggaagca
    29401 gctattgcta agacaaggca aaatactggc ttgattctaa actttgctct taattatggg
    29461 ggtcgcgcgg aaatcaccaa tgctgtcggt ctcattgctc aagatgtcct agacgccaag
    29521 ctgaaccctg gtgacattac cgaggatttg attgccaact atttgatgac ggatcatttg
    29581 ccctatctct atcgcgatcc tgaccttatt atcagaacga gcggtgaatt gcgcttgagt
    29641 aattttatgc cttggcaatc agcctatagt gagctttact ttacgccggt gctgtggcct
    29701 gattttaaaa gagctgaact actaaaggcc atagaggatt ataaccatcg tcatcgccgt
    29761 ttcggtgcta tttaaggaga gagtatgaga gaacgtttca tttggggtgg tgttgcagct
    29821 gctgttttcc tacccttttt actcattggc agcttaccct ttcaattgtt tgtaggtgtg
    29881 cttgccatga ttggtgtatc agagctgtta agaatgaaga ggcttgaggt cttttccttt
    29941 gagggtgttt ttgccatgct agcagctttc gttttgacag tgccgttgga tcattacctg
    30001 acctttttgc cgatggacgc tagttttgct tgttacgggc tgttggtgtt tttcctttta
    30061 gcaggaatag tgattagcag cgattcttat ggctttgagg atgctagctt tccgattgca
    30121 gctagcttat atgttggtat tggctttcat aatctggtta atgcgcgaat gacagggata
    30181 gacaaggttt ttctggctct ttttattgtc tgggcgactg atattggagc ttacttgatt
    30241 gggcgccgat ttggtaagcg aaagctcctg ccaaaaatat cacccaacaa aacaattgag
    30301 ggcagccttg gtggtatagt cagtgcggtg cttgtttcct ttgtgtttat gctctttgat
    30361 aaggctgttt atgctcctca tcattttgga acaatgttga ttttggtggc tcttttttct
    30421 atttttgctc agtttggaga tttggttgaa agtgctgtca aaagacattt cggagttaag
    30481 gactcaggca aattgattcc aggccatggt ggtattttag atcgttttga ttcgatgatc
    30541 tttgtttttc ccattatgca tctatttggg ttattttaaa gctcattatc aatagactga
    30601 aaggaaatct atgttaggaa taattacctt tattattatt tttggtattc ttgtgcttgt
    30661 ccatgagttt ggccatttct attttgctaa acgatctggt attttagtca gagagtttgc
    30721 tattggcatg ggaccaaaac tcttttcgca tgttgatcag caaggaacgc tttacacgat
    30781 ccggctatta ccgcttggtg gctatgtgcg aatggcaggc tggggtgatg acacaactga
    30841 gataaaaaca ggaacgcctg ctagcttaac gcttaatgat cagggcttgg tcaagcggat
    30901 taacctgtct cagagcaagc ttgatccgac tagcctgcct atgaatgtga ctgcttatga
    30961 cttagaagat aagttgacga ttacagggct ggttcttgat gagatcaaga cctattcggt
    31021 agaccatgac gcgaccattg tcgaggagga cggtacagag atccggattg cgccgcttga
    31081 tgttcagtat caaaacgcaa gcattggcgg tcgtttgatc accaattttg caggacctat
    31141 gaataatttt attctaggta ttgttgtctt tattttgttt gcctttgttc aaggtggtgt
    31201 ggctgattat catagcaacc atattcgtgt ggtggaaaat ggcgcagcag ccaaggctgg
    31261 tattagagac aatgatcaga ttttagagat taatcatcaa aagattaatg actggtatga
    31321 gttgacgcag gccgttactg attcagcagc agatgttaag gctaagggca agctagagat
    31381 tacctatcag acaggtgatc aggttaagac tatagcactg aagcctgaaa aaaaaggcga
    31441 tcagtacctt attggtgtcc agtacccact aaaaacaagt ctgacagaca agctaatagg
    31501 tggctttgag atggctggta atggtgctct agtgattgtc actgctctaa agagtttgat
    31561 tacctccttt agcctagata aattaggtgg gccagttgcc atgtatcaga tgtccaatca
    31621 ggcagcaaag aatggtttag agtctgtctt gtccttgatg gcaatgctct ctatcaattt
    31681 agggattttt aatttgattc cgattcccgc actagatggt ggtaagatcc tgatgaatgt
    31741 gattgaagca cttcgtcgta agccattaaa gcaagagaca gagacttata ttacccttgc
    31801 aggtgttgcg attatggtgg tactcatgat tgcagtgacc tggaacgata ttatgcgagc
    31861 ctttttccaa ggctgatggt ctctctcatt taaaggagag cctaaaaggc ttaatgtaac
    31921 agaaataaca agagatatag tgtcattatt gtggttctaa gaccttgcaa atgcagcaaa
    31981 agcttagcca atatagctca ttttgtctct tttttagaaa tgaattctca acgaaaggaa
    32041 agagagctgt tgaccaagct gggctaaggc ctacagctga aatcaaaatg ctagacctgc
    32101 tattagtcta agggcgtttt gagctgctct ctatagctta ttttaatgaa acaaagtaaa
    32161 atgcttatcc caaccctgcg cgaaatgcca agtgacgctc aggtaatcag tcatgccctc
    32221 atggtgcgtg cgggctatgt ccgtcaggta tctgccggta tttatgccta tttgccatta
    32281 gctcatcgta caattgaaaa attcaagacg attatgcggc aggaatttga caaaattggt
    32341 gctgttgaaa tgctagcacc tgccctttta acagctgacc tctggcgtga atcaggccgc
    32401 tatgagactt acggtgagga cctttacaag ctaaaaaacc gcgacaaatc agactttatc
    32461 ttaggtccta cccatgaaga aacctttact acactggtgc gtgatgcggt taaatcctat
    32521 aagcagctgc cgctcaatct gtatcagatt caatccaaat atcgtgatga aaagcgtcct
    32581 cgtaatggcc tgcttcgcac acgtgaattt atcatgaagg acggctatag ctttcatcaa
    32641 agctatgatg atttagatgt cacctatgac gcctatcgtc aggcctatga ggctattttt
    32701 accagagcag gcttggattt caaaggaatt atcggtgatg gtggtgctat gggtggtaag
    32761 gattcgcagg aatttatggc tatcacaccg gaccgtacta atttagaccg ctggctggtc
    32821 ttagacaagt ctattccgtc attggctgac attccagagg aggtcttgga agagattaag
    32881 gccgagctgg cttcatggct ggtttcagga gaggacacca ttgcttattc aagtgaatca
    32941 agctatgctg ctaaccttga gatggcaacc agtgagtaca agtcctcatc aaaggtaaca
    33001 gccttagatg atctcgtcga gattgagaca ccaaattgta aaaccattga tgaagtggcg
    33061 gcctttcttg acgttgctga gcatcaggtc attaaaaccc tgctctttat ggtggaccat
    33121 gagcctgtgc ttgctttatt ggttggaaat gaccagatca atgctgtcaa attgaaaaac
    33181 cacctcggtg cagacttctt agagccagct agcgaggagg aggcgcgtgc tatcctaggt
    33241 gcaggctttg gttcacttgg tccagttcat ttgacagatg gtatccgtat tgtggctgat
    33301 cgtaaggtcc aagaccttgc taatgctgta gctggagcca ataaagatgg ttatcacctg
    33361 actggtgtca atccaaatcg tgatttccaa gcagagtatg ctgatattcg tgaggtaaaa
    33421 gagggagaga cctctccaga tagacatggc gtgctgcagt ttgccagagg tattgaaatc
    33481 ggtcatatct ttaagctggg gacccgctat tctgatagca tggcagctaa tatccttgat
    33541 gagaatggca gagcagttcc gattgtcatg ggctgctatg gtattggggt tagtcgtatc
    33601 ctatcagcag tcattgagca gcatgctcgt ctctttgtca gcaagacacc aaagggtgat
    33661 tatcgctatg cttgggggat taatttccct aaagagctag ctccgtttga tgtgcatttg
    33721 attaccgtta atgtcaagga tcaggaggcg caggacctga cagaaagagt agaggctagt
    33781 ctgatggcca agggctatga tgtcctcact gatgaccgca atgagcgtgt cggctctaag
    33841 ttctctgata gtgatttgat tgggcttccg attcgtgtga cgattggtaa aaaagcagct
    33901 gagggcattg ttgagatcaa aatcaaagca acaggtgaca gcattgaggt gcacgctgat
    33961 agcttgattg aaactcttga cattctcaca aaggacaact aatgatatga ggtcaacgat
    34021 ggttgatctc tttttgtatg ctataatgaa agcatgacaa ttgaggaatt acagcagctg
    34081 gtgctagcag atcatgagct aatgactatt ctaagcatta tagagacctt gcctttaaag
    34141 gattgttggc tggcagcagg tgcaattcgg aacgctattt ggaatcattt agcttatggg
    34201 ataggctttg atccgctgac agatgtagat gtggtctttt ttgaccctga gatctcttac
    34261 gaagctgagc agctgctaga agagcagctt aagtgtgctt atcccatgta ccaatgggag
    34321 gttcgcaatc aagcctatat ggcagcacat aaccccaaga cgcctcctta tcgatctagt
    34381 caagacgcta tcacaaagta tccggagcgc tgtacagcga ttgctgttag acttgtagga
    34441 ggacagctag aggtttttgc tccctatggt ttagcagaca ttagtcactt tgtctgtcgg
    34501 ccaacaccgc attttttaga ggattcagag cgtatggact gctataggca gcgcctagca
    34561 aagaaggact ggcacaagaa atggccacag ctgacctacc acgactgcta agtcagagga
    34621 aacaaagcag gctaggagct ccgtacagcc aagcaattag tccgctccca gacccgttag
    34681 ctacagctct cacctagtca aaacaagcac atgaacagat cattggcaga tagccttgcc
    34741 tttgcagata ttgtcacacc ctatttagct gtaccatgtg tcttatgata ggcgtgatag
    34801 tgctgtcaga agcgccagct gagccagaaa aagcgttaag cctacagcaa ggggctttta
    34861 acctttggta tgttgtcttg taggagaggt cgaaaatgat cactatttat gataaaatag
    34921 accctaagaa aatcaggaga aagctatgtc agatttattc ggtaaattga tggaacaaat
    34981 tgaaatgcca cttgagataa gacaatcaag tgccttttcg tctgctgata ttatcgaggt
    35041 caaggtgcat tcagtgtctc gtctgtggga atttcatttt tcctttgcag aggttctccc
    35101 gatagagagc tatcgagagc tgtcagatag gcttgtgaga acctttgagg cagcagatat
    35161 taaggtaaca tttgacatca aggcagagac aattaattat tcggatcagc tgctgcaagc
    35221 ctactatcaa gaagcatttg agcatgagcc ctgtaatggg gctagcttca agtcatcttt
    35281 ttctagactt caggtcaggt atgaccatca tcagctgatc attatggcac ctgactttgt
    35341 gaataatgat cactttagga aaaatcattt acccaatctg gcagctcagt ttgagcgctt
    35401 tggctttggg aggctagcga ttgatatggt gtctgatcag gagatgacag accatttgac
    35461 aaaggacttt gagaccaacc gtcaggctct ggtggaaaag gctgtacagg ataatatcgc
    35521 agcacagcaa tcattggagg ccatgcagcc accagctgag gaggcagcac caagcccaag
    35581 ccttgactat agagagcgta tggctcagcg ccaagcaagc tttgataagg cggtcattac
    35641 accaatgatt gaggtggata cagaagaaaa tcgcattgtt tttgaaggaa tggtctttga
    35701 tgtggagcgc aagacgacaa gaacaggccg ccatatcatc aacttcaaga tgacagatta
    35761 cacctcctcc tttgccatgc aaaaatgggc caaagatgac gatgagctca gaaaatttga
    35821 tctgattgcg aagggagctt ggctgcgcgt tcagggaaat atcgaaaaca accccttcac
    35881 caagagccta accatgaatg tgcagcaggt taaggcgatt gttcaccatg agcgtaagga
    35941 tctcatgcca gaagggcaaa agcgtgttga atttcatgca cacactaata tgtccacaat
    36001 ggacgctcta ccgacggtag aagacctgat tgatacagca gccaggtggg gacatcaggc
    36061 agtagcgatt actgaccacg ctaatgttca gagctttccg catggctatc atagagcacg
    36121 caaggcagga atcaaggcaa tctttggctt agaggccaat attgttgagg ataaggtacc
    36181 tatttccttc aatcctgtcg ctatggacct gcatgaagcc acctatgttg tctttgacgt
    36241 ggagaccacc ggcctttctg ccatgaacaa tgatttgatt cagatcgcag cttccaaaat
    36301 gttcaaggga aatatcattg agcagtttga tgagtttatc aatccaggcc accccttatc
    36361 tgcttttaca acagaattga cagggattac agataatcat ttggtaggag ctaagcctat
    36421 acagcaggtg ttagaggcat ttcaggcctt ttgtcagggc actatcctag ttgcccacaa
    36481 tgctagcttt gacgtgggat ttatgaatgc caactacgat cggtatggtt tagcaaaaat
    36541 cagccagcca gttattgaca ccctggagct tgccagaaac ctgtaccctg agtataagcg
    36601 gcatggcttg ggccctttga ctaagcgctt tcaggttagc cttgagcacc atcacatggc
    36661 caattacgat gctgaagcaa cagggcgttt gctctttatc ttcctaaagg aagctagaga
    36721 aaagcatggg attacaaacc tgcttcagct caatacagac ttagtggcag aggattccta
    36781 taagaaagca cggatcaagc acgccacgat ctatgttcaa aatcagctag gtctcaaaaa
    36841 catgtttaag ctggttagcc tttcaaatgt gaaatatttt gaaggtgtgc ctagaattcc
    36901 aagaaccgtc cttgatcagc atcgtgaagg cttgctgctt gggacagcct gctcagacgg
    36961 cgaggtcttt gacgctgttt tgacccaagg aattgacgct gctgttgatc tggccaaata
    37021 ctacgatttt atcgaaatca tgccgcctgc aatttaccag cccttggtag tccgagagct
    37081 aatcaaggat caagcaggag ttgagcagat tattcgcgat ttgattgagg tcggccgcag
    37141 agctgaaaag cctgtcctag ctactggaaa cgtgcactac attgagccag aggacgccat
    37201 ctatcgtgac attatcgttc gtagtctagg gcaaggtgcc ctgattaacc gtactattgg
    37261 ccgcggagag gctgccaagc ctgtcccgct accagaggct cattttagaa caaccaatga
    37321 aatgcttgat gattttgcct ttttaggtca ggacttggcc tatgaggttg tggtgcaaaa
    37381 tacccaagcc cttgctgatc gaattgaaaa ggtggaggtt gttaaggatg atctgtacac
    37441 cccatatatt gataaggcag aagaaaccgt tgctgagctg acttatcaaa aggcctttgc
    37501 tatctatggc aacccacttc cagatatcat tgatctgcgc attgaaaagg agctaacgtc
    37561 cattttggga aacggctttg cggtgattta tctagcctca caaatgctgg ttaatcgctc
    37621 taatgagcgt ggttatctgg taggctcacg tggctctgtt ggttcaagct ttgttgcgac
    37681 catgattggc atcacagagg tcaatccaat gccgcctcat tatgtctgcc caagctgcca
    37741 gcagtcagag tttatcacag atggctcggt cggctctggc tatgatttgc caaacaaggc
    37801 ctgtcctaga tgtgggacgc tgtacaaaaa ggacggacag gatattcctt ttgaaacctt
    37861 ccttggcttt gatggtgata aggttccaga tattgatttg aacttctcag gagatgatca
    37921 gcccaatgcc cacttggacg ttcgtgatat cttcggggaa gaatacgcct ttcgtgcagg
    37981 tactgttggt actgtcgctg aaaaaacagc ctatggcttt gtcaagggct atgagagaga
    38041 ttatggcaag ttttacccag atgcagaggt tgatcgtcta gctgctggtg ctgctggtgt
    38101 taagcggacg actggtcagc accctggtgg gatcgttgtt atccctaact atatggacgt
    38161 ttatgatttt acacctgtgc agtttccggc agatgatgtg acagcctcat ggcagacgac
    38221 ccactttaat ttccatgata ttgatgaaaa tgtcctaaag ctcgatgtac tcggtcatga
    38281 tgatcccacc atgattcgta agctgcagga tttatcaggt attgatccga ttactattcc
    38341 agcagatgat cctgacgtga tggcactttt ttctggaaca gaggtgctcg gagtgactcc
    38401 tgaacaaatt ggaacaccaa caggtatgct tgggatccca gagtttggaa cgaactttgt
    38461 tcgtggcatg gtgaatgaga cccacccaac gacctttgca gaattgctgc agctatcagg
    38521 tctatcgcat ggaacggacg tctggctggg taatgctcag gatctgatca aagaaggcat
    38581 tgccacccta aaaacagtta tcggttgtcg agatgacatc atggtttacc tcatgcatgc
    38641 tggtctagag cctaagatgg cctttaccat catggagcgt gtgcgtaagg ggctctggct
    38701 aaagatttcc gaggaggagc gcagctccta tatcaaggcc atgcggcaaa acaacgtccc
    38761 agactggtac atcgaatcct gtggtaaaat caagtacatg ttccccaagg ctcacgctgc
    38821 cgcctatgtt ttgatggcat tgcgagtggc ttatttcaag gttcatcacc ccatcatgta
    38881 ttactgtgct tatttctcta ttcgtgccaa ggcctttgag ctcaaaacca tgagtggtgg
    38941 gctagctgct gtcaaggctc gcatggagga catcagcaac aagcgcaagc gcaatgaagc
    39001 ctcaaacgtt gaaaatgacc tgtttaccac tttagaaatt gtcaatgaaa tgcttgagag
    39061 agggtttaag tttggcaagc tagaccttta caagagcgag gcaactgagt ttcaaattga
    39121 aggggatacc ctaattccac cttttattgc cttagaaggc ttgggagaaa acgttgctag
    39181 acaaatcgtc aaggctcgcc aagatggtga atttctatca aaaatggaat tacgcaagcg
    39241 tggtggtgct tctgccactc tagttgataa gatggacgag ctgggcattt taggaaatat
    39301 gccagatgac aatcagctga gtctatttga tgactttttc taagattgca cagccctaat
    39361 attgtctatg ttagcttgtc atacagtgaa gagcagggca ggaaggcttc ctgtcctctt
    39421 tttgtcaata cgcaaagaaa gcccaaaaaa gaacgaggaa aagcatgaat gaattagaca
    39481 aaaatcctgc cttaaaggca atggttgttt ttagaaaagc acagcgtacc ttagatgctc
    39541 aaagctccgc cttttttcaa aaggccaatc tgactcctac ccaatttagc gtcttagagg
    39601 tgctttattc caaaggaagc atgagaatta acaagctcat cggttctctc ttggcaacct
    39661 ctggcaatat gaccgtagtg ctgaaaaata tggagagaaa tggctggatc agccgctgcc
    39721 aagatgctaa agataagcgt gcctgcttgg tacagctaac gccagagggc aaagccttga
    39781 ttgagactat cctacctgag catatcaaac gtgttgaagc ccttttttca gtgctgacag
    39841 agactgagca aaaacaattg attacgcttt taaagaaatt taaagaactc taagcaaatg
    39901 gctttacagg atctcccaag taggatataa tcactacata gtacaaaaag atactaacta
    39961 gtcataataa gtcatcaaga cagcagatgg ctagttacca gataatcaat gggagacaaa
    40021 gcatgaaaca aattttaatc attaatggtt cattacggac aggttcattt aatcatcagc
    40081 ttgctcaagc ggctgagcag ctacttgaag gcaaggcagc tgtatcttac ttggactggg
    40141 aacaggtacc tatgtttagt caggatttag aagcaagcac ccctgagtca gtggcaggcg
    40201 tacgagaagc cattcaagca gcagatgcta tctggatttt ttcacctgtc tataattttg
    40261 caatcccggg ctctatcaaa aacctattag actgggtatc acgcgccctt gatttgtcag
    40321 acccatcagg accatcagca atcaatggta aggtagttac cgtatcatct gttgctaatg
    40381 gtgggcacga gcagctattt gcgcaatacc aggacctgct gccctttatc cgtacgacag
    40441 tagttggtaa ctttaccaaa gccgctgtca atccagaagc atgggcgaca ggtgttcttg
    40501 atatttctga ggaaacaagg caaagccttg cagcacaggc agaagccctt cttgaagcca
    40561 ttcactaaga ctctctgagc attaaacaga taaagctgca gctaggatca aaaagcagct
    40621 agacacataa aaagagctta aaccagaaat gtacggcact ccaaaagcta gacaaaaact
    40681 ctagcgattg gggtacaggt caaaacggtt ttaagctctt ttttagactt attttatagt
    40741 agtaacttaa ttaagaatta gcataccctc tttagcctca aaggggtttt tcgcattaat
    40801 acggtcatag aataagacac cattaatatg atcaatctca tgctgaacca cgatagcatt
    40861 gtagcccttt agcttaatgc ggtgcttttc attgtgctta tcgtaatatt ccactgtcac
    40921 acgcgcatga cggacgacat agccttccac cacacgatca acagacaaac acccctcacc
    40981 gtcagcaaga gcagcgtctt gaacagaatg agacacaatt ttaggattat agagcacttc
    41041 ctccatgctg taagcctcct taggtggatt gccctcgctg tcttcaggat ttggaaccag
    41101 aacagcgatg atacgctttg acacatcaat ctgaggtgct gctagaccaa ctcctgctcg
    41161 aagccctaat ttttctccca tgacagggtc ttgagaatgc tttaaaaatt gcatcatttt
    41221 ttcacctaaa atgatgtcat catcactaag aggaaactcg acctccttag ccacagcacg
    41281 aagcgtagga ttgccttcgc ggataatatc attcatatca atgagatgct gtgctttaat
    41341 taatttatct tgtgcagaca ttttgcctcc ctttttttat atttgataat ggctttacta
    41401 tatcacaaaa tccttatttt taaaagataa ggcaggccag tgatgacgat attagctaac
    41461 tctatcagat atattaaatt atttaaaaaa tagttcgtta attagcacga catatatata
    41521 agaaatacac aggaattcta ataattaata gataaaaaat gataatcgtt cgtaaataaa
    41581 tcaaacatct aatctaaaaa aattatattg ttctgattgt tcggtaatta aagcaatagc
    41641 gcttgtcgaa aaactaatgt tctcttaata tcaggtagcc atgccaaggg ttttgtgtta
    41701 aagtatagga cgttcaaaaa atgaaatgga gagactaatg agaacacaat tgaaaaaatt
    41761 gctggcagga acagcagcag gtaccctgct gctgtttaac ctgacctgcg gaatgattaa
    41821 tgcttttgca gagcagtatt acgggtggag tgacgggagt agcagctatc cgagtgcttt
    41881 gtatgttaca ccggtaggag atactacgaa aaagatagct attcctgttt attgctttga
    41941 ctataagttt caggagccac ttgcttggaa agaaataact caaccgtcac acttgattgt
    42001 ctatgataag tatgatggca aaaatttgat ggcagcactg gttgaaaaac ctaatatggt
    42061 aagctatgag actaaaacta aacttcaaac acttttaaag acaaagtcaa atctaataac
    42121 tgcaatttta agtagaggtt atccaaacaa aagttttttt gataagtata aaaaattaac
    42181 tgatgaagat aaaagacgag tgacacaatg tgctctttgg tatcatactg acaatatttc
    42241 agaacaagat cttatcacaa aacatttgga tggggattca ggtgaaaaaa gtcaagcgct
    42301 aaaggagtta ataggggttg taaaaaatac ttctaatgag ttaggagagg gattaacctt
    42361 ctatactcgt tataatgata gatatggtcc taaatatcaa aacctaatag gctcaattat
    42421 tgttcccgaa gagcctcaga atgatcttga aattggtggt ggaaatgtta ttgatttaaa
    42481 ctaccaatct ggaccaatgg tagaagaagg tggtcattca ggtggcaagg aagaggtcga
    42541 ggacactaaa aagcctgatg tgattattgg tggtcaggga agcgttactg agactactga
    42601 ggatactcaa aagggtatga gtggcagtac tgagactcag ccagaggttg aggatactaa
    42661 gcagccacaa tcagatatta tcctaggcgg acaaggcaat gtgattgaca caactgaaaa
    42721 tacccaagag ggcatgggtg gccaatcagg tgatactaca gagactgagg ataccaagca
    42781 gccacaatca gacattatcc taggtggaca gggcaatgta attgacacca ctgaaaatac
    42841 tcaagagggt atgagtggtt ccaacaatgg tcaaacattt gaggaggaca cacgtcctaa
    42901 gctggaattc cattttgata atgaagtgcc taacgatgat gacgctccta aaccagagca
    42961 accagaacag ccagagaagc cggagcaacc aaggaagcca cagcaggagc agcaaagcct
    43021 accacgtcca atagagggca accagtcatt gccaaaaaca catgaggcaa aaggtgtact
    43081 ggctctagta ggagtaggaa tccttgctat gctaggacta ggcttttggt ttagacctta
    43141 tcaaaaagac taaatcaagg ctcagcagct atttaagcta aacagctgtg ctcagctaaa
    43201 tgataaaaca attaagattg gagaatgtgg ctattagtag cttctccaat cttttttgat
    43261 agcagcatgt gctttttctg ccgtatttta ttgagaataa tagttgacca gtctaggcga
    43321 ttttgctaga atagagaggt cgcaagacag actaactttt tcttggtttt aggagtgcca
    43381 accctaaaac tcggattaag caaaaaagga gaattattat ggcaatctca aaagagaaaa
    43441 aaaatgaaat tattgcacaa tatgcacgtc acgaaggtga cacaggctca gttgaggttc
    43501 aggtagctgt ccttacttgg gaaatcaacc acttgaacaa ccacatcaag gagcacaaaa
    43561 aagaccacgc aacttatcgt ggattgatga aaaaaatcgg acaccgtcgt aacctattag
    43621 catacctacg tcgtacagat gttaaccgtt accgcgagtt aatccaatca cttggacttc
    43681 gtcgttaatt ggcttgacag aggtcatttt agagataacc aagttctatt gaaaaaagat
    43741 ctgctagtgt actgaccccc aaaagttgga cacgacatat tagtgaaagg atttagttct
    43801 gtattgcaca gg
//
LOCUS       DARYYD010000012        43765 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.012, whole genome shotgun sequence.
ACCESSION   DARYYD010000012 DARYYD010000000
VERSION     DARYYD010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43765
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.012"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(152..742)
                     /locus_tag="TV188_000570"
     CDS             complement(152..742)
                     /locus_tag="TV188_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533953.1"
                     /translation="MKKVKQLIIAMIASLLLIANTVPSIVYASEVTKIQQEEKVIEEK
                     LSQPLEISKSELDTLIQEKKALYPNLTEQEMREIAYKAMSPYTFRASVWDGQGVTLDE
                     FAWAFDVIVGGLISGYATIGKYVAKHGVAAARAVLSRAAKAAAQRLGVLTGFISGLLR
                     AAFSVINIYYNVGYALAQYVDARDYHPNNGRINAWA"
     gene            1265..3307
                     /locus_tag="TV188_000571"
     CDS             1265..3307
                     /locus_tag="TV188_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1533954.1"
                     /translation="MVDSKAVVILMTLMTYQDLSLYELSVKTKFTIREIKDRIDELNE
                     FLAQHELSELDATRSGYRISQQLKAESDHLFTLINAEQVYLSQAERINLIYLYTFCRR
                     DFVSNSHYQDFLKVSKNTALTDIKALRQKLADVDLELKYTRASGYILVGDEINKHRLA
                     LVMIATLLKSPIGLWALDYILASWHYQVSFEALEKRVSHFYQTFQMSPILDRLQVCLY
                     AVIFILCRYQRRVDRVKQRQVVVSEQLDQLTALLVAEIMQQLSLKYQLFEADEAYFQL
                     LLAGCFEGEGTVGDDFFESLTVAIVDQMQGVALLSFSQADQLKENLKRHLIPAYYRLR
                     YGLPSDNDYTLRIKDSYSELFDLVKQSLEPLAKELGSPIPDSEIAYFVLHFGGYLKQQ
                     GRDFHRQAYQAVIVCPNGVSSSLMIKEHLKLLFPDIAFRGLSRLDQLGQLDKSGYDLV
                     FSTIRLETDKPFYLVPMIMTDEQAFQLVSLVNRDFPDIGYRLEVEELLHLISSYAVIH
                     QKEKLRFALQQYLRQGVKRKDIRPVLQDLITKKTYQSTSEQLGWREAIYLAAQPLLES
                     GQIQASYPEAMIAKVEEFGTFINLGKGIAIPHARPEDGVNQVGMSMLVLEHPIYLLDD
                     PKQEIRLLICIAAIDNETHLKALSRLTTILRDNEQVKALLASKSFEDIKTIIAEEA"
     gene            3309..3596
                     /locus_tag="TV188_000572"
     CDS             3309..3596
                     /locus_tag="TV188_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1533955.1"
                     /translation="MALRIGTACGSGLGSSFMVQMNIESVLKDLGVTGVEVEHYDLGG
                     ADPTAADVWIVGRDLADSAEHLGDVRILNSIIDMDELTSLVKAICQEKGLV"
     gene            3609..4952
                     /locus_tag="TV188_000573"
     CDS             3609..4952
                     /locus_tag="TV188_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEL1533956.1"
                     /translation="MTFLLDIVSTPAILVALIAIVGLLLQKKPAPDIVKGGIKTFVGF
                     LVVSGGAGIVQGSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFTGMI
                     FNILIARFTRFKYIFLTGHHTLYMACMIAVIMSVAGLTSVSLIVFGGLALGIIMSVSP
                     ALVQRYMIQLTGNDKVALGHFSSLGYWLSGFVGGLVGDKTKSTEDIDFPKSLAFLRDS
                     TVSITLSMAIIYLIVAIFAGPTWISKELSSGTHGLVFALQLAGQFAAGVFVILAGVRL
                     ILGEIVPAFKGISEKLVPHSKPALDCPIAYPYAPNAVLIGFVSSFVGGLVSMAVMIVS
                     GTTVILPGVVPHFFCGATAGVIGNASGGVRGATVGAFLQGVLISYLPIFLMPVLGGLG
                     FEGSTFSDADFGLSGILLGTLNSIGGVTAIVIGIFVILAGLVGLSVVGKSVAKEE"
     gene            4955..5812
                     /locus_tag="TV188_000574"
     CDS             4955..5812
                     /locus_tag="TV188_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1533957.1"
                     /translation="MVLSDEPLTDVKRFAAEIRLNTLETLNHLGFGHYGGSLSIVELL
                     AVLYGEIMPMTPELFVQSDRDYLVLSKGHAGPALYSTLYLKGFFDKAFLQSLNTNGTS
                     LPSHPDRLLTPGIDMTTGSLGQGISVATGIAYAQALEQSPHYTYAIVGDGELNEGQCW
                     EAIQLAAHQQLSHFIVFVDDNKKQLDGTTEAICRPGDFVEKFTAFGFESLRVDGRDVQ
                     AIFEAIRALQASSSHKPKCIVLDTVKGQGVSQLESMAANHHLRPTAAEKEMLAAAVRK
                     LRASLEVTR"
     gene            5809..6741
                     /locus_tag="TV188_000575"
     CDS             5809..6741
                     /locus_tag="TV188_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEL1533958.1"
                     /translation="MTRASQEMRHVYRDFLIAANQEHPEVVVLEADLSSSMATNHLDQ
                     VFGKRYINVGIMEAEMVGLAAGLAIKGYKPYLHTFGPFASRRVFDQLFLSLAYAQLGA
                     TVIGSDAGVSAEMNGGTHMPFEDLGLLRLIPRAIVYEVSDDVQFKAVLKETLSLDGLK
                     YIRTIRKKPEAIYQGHEDFSNGYCLLRQGKDLVLACSGIMVKRCLEVADKMAEQGYSI
                     GVIDVFRVKPLADELKGLLTGSPVLTVENHNRIGGLGSAICELLAQESNTPVYRMGVD
                     ERFGQVGQMDYLLEEYQLTPAAIEQQVLRILAAD"
     gene            7293..9188
                     /locus_tag="TV188_000576"
     CDS             7293..9188
                     /locus_tag="TV188_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase"
                     /protein_id="HEL1533959.1"
                     /translation="MTTYQEDFYQAVNGQWAETAVIPDDKPRTGGFSDLADEIEDLML
                     TTTDAWLAGEHVPNDAILENFVKFHRLVADYDKRDQVGVAPALDLIEEYKALGSFAEF
                     ASKVADYELNGKPNQFPFSVAPDFMNAQLNVLWAEAPGLILPDTTYYAKDNDKGKELL
                     AIWRGMQEELLPKFGFSHEEVKDLLDKVITLDKQLADYVLSREEYSEYAKLYHPYDWA
                     EFTKLVPELPLDNIFTVILGEVPDKVVVPEERFWTEFAADYYSEKNWELLKAWLVLTA
                     AGAYHAYLTDEIRVLSGVYSRALSGTPQAMDKKKAAYYLAQGPFNQALGLWYAGEKFS
                     PEAKADVEHKVAKMIEVYKSRLETADWLAPATREKAITKLNVITPHIGYPEKLPETYA
                     KKVIDDKLSLVENAQNLAKISIAHSWSKWNKPVDRSEWHMPANMVNAYYDPQQNQIVF
                     PAAILQAPFYSLSQSSSANYGGIGAVIAHEISHAFDTNGASFDEHGSLKNWWTDEDYA
                     AFKERTDKIVEQFDGLDSYGAKVNGKLTVSENVADLGGVACALEAAQSEPDFSARDFF
                     INFATIWRMKAREEFMQMMASIDVHAPGQWRTNVTLTNFDEFHQEFNIKEGDPMWRAP
                     EDRVIIW"
     gene            complement(9388..10428)
                     /locus_tag="TV188_000577"
     CDS             complement(9388..10428)
                     /locus_tag="TV188_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEL1533960.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDMEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVVEVNAETDFVAKNAQFVELVNATAKAIAE
                     GKPANNDEALALIMPSGETLADAYVNATATIGEKISFRRFALVEKTDDQHFGAYQHNG
                     GRIGVITVVEGGDEALAKQVSMHVAAMKPTVLSYTELDPQFIKDELAQLNHAIELDNE
                     SRAMVNKPALPFLKYGSKAQLSADVIAQAEEDIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLDSVNAKAISFARFEVGEGIEKKANDFES
                     EVAATMAAALNN"
     gene            complement(10596..11366)
                     /gene="rpsB"
                     /locus_tag="TV188_000578"
     CDS             complement(10596..11366)
                     /gene="rpsB"
                     /locus_tag="TV188_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEL1533961.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKLADQAYEFVRDAAANDAVILFVGTKKQAAEAVADEATRAGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEEGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNADPDDIDVIIPANDDAIRAVKLITAKLA
                     DAVIEGRQGEDAEVAFEADTQAESIEEIVEVVEGSNEA"
     gene            complement(11827..13359)
                     /gene="ahpF"
                     /locus_tag="TV188_000579"
     CDS             complement(11827..13359)
                     /gene="ahpF"
                     /locus_tag="TV188_000579"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HEL1533962.1"
                     /translation="MALSPDIKEQLAQYLNLLESDLVLQAYLGSDDSSQKVKDFIEEI
                     AAMSDRITVEETTLTRQPSFKITQKGQDSGVIFAGLPLGHEFASFILALLQVSGRAPK
                     IEQDIIDRIRAIDRPLSFETYVSLTCHNCPDVVQALNIMAVLNKNISHTMVEGGMFQE
                     EVKAKGIMSVPTVFLNGEEFTSGRATIEQLLEQIAGPLSKEAFADKGVYDVLVIGGGP
                     AGNSAAIYAARKGLNTGLLAETFGGQVMETVGIENMIGTLYTEGPKLMAQVEEHTKSY
                     DVDIIKAQLATSIEKKDLVEVTLANGAVLKAKTAILALGAKWRSINVPGENEFKNKGV
                     TYCPHCDGPLFEDKNVAVIGGGNSGLEAALDLAGLAKHVYVLEFLPELKADKVLQDRA
                     AKTDNMTILKNVATKDIVGDDHVTGLNYIERDSNQEKHLDLEGVFVQIGLVPNTAWLK
                     DSGISLTDRGEIIVDKYGSTNIPGIFAAGDCTDSAYKQIIISMGSGATAAIGAFDYLI
                     RQ"
     gene            complement(13380..13940)
                     /gene="ahpC"
                     /locus_tag="TV188_000580"
     CDS             complement(13380..13940)
                     /gene="ahpC"
                     /locus_tag="TV188_000580"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002273221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HEL1533963.1"
                     /translation="MSLVGKEIAEFSAQAFHNGKFITVTNEDLKGKWAVVCFYPADFS
                     FVCPTELGDLQEQYEILKSLGVEVYSVSTDTHFVHKAWHDDSDVVGTITYPMIGDPSH
                     AISQAFDVLGEDGLAQRGTFIIDPDGVIQMMEINADGIGRDASSLIDKIRAAQYVRKH
                     PGEVCPAKWKEGAETLTPSLDLVGKI"
     gene            14288..14358
                     /locus_tag="TV188_000581"
     tRNA            14288..14358
                     /locus_tag="TV188_000581"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14320..14322,aa:Cys,seq:gca)
     gene            complement(14465..15532)
                     /locus_tag="TV188_000582"
     CDS             complement(14465..15532)
                     /locus_tag="TV188_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1533964.1"
                     /translation="MAKFRKRGDKWSYRIYYTDSQGNKREKSKGGFKTKALASAAAIK
                     VEAELNKDIDDISLYDFCKEWAKIYKRPHVVDKTWETYTKNLKHIKKYFGDIKLNNVT
                     HTFYQKTINEFAKKYAQETLEKLHYQIKGAVNVAVRDGLIKTNFAEGAIVKSQKEARA
                     KEFDFLEEDEYLNLIKVTSEKYQYVSYFTLYIIAVTGLRFAEATGITWSDIDFEKGFI
                     DINKSFDYSKTQEFKETKNEQSKRQIPIDQQTIKLLRAFKENYYNENKLNRVLYGASN
                     SLCNRLVKKIVGRPVRNHSLRHTYASFLILKGVDLISISQLLGHENLNITLKVYAHQL
                     DKLKEKNNQAIKDIFGNLTDF"
     gene            complement(15659..15934)
                     /locus_tag="TV188_000583"
     CDS             complement(15659..15934)
                     /locus_tag="TV188_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1533965.1"
                     /translation="MRYKVLFTKKAKKQLKKLDRSTAKQLYQWIMTNLDGTDNPRRYG
                     KALQANRTGEWRYRLGNYRILAEIIDDEVVIEVFKIEHRSSVYKIKR"
     gene            complement(15924..16142)
                     /locus_tag="TV188_000584"
     CDS             complement(15924..16142)
                     /locus_tag="TV188_000584"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEL1533966.1"
                     /translation="MIAMTLNLEKDDAYIADYIKENNIDTSNLTVDQFLEIIEDAKDL
                     YELRKAKAEDDGTRFSMEDVAKELGFAL"
     gene            complement(16158..16679)
                     /locus_tag="TV188_000585"
                     /pseudo
     CDS             complement(16158..16679)
                     /locus_tag="TV188_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059208.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            17068..17274
                     /locus_tag="TV188_000586"
     CDS             17068..17274
                     /locus_tag="TV188_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1533967.1"
                     /translation="MLNIDKVRKEKGVAIVDMADFLGVRAQTVSDKLRGTYDFKFTEA
                     LALQQKFFPEYDLEYLFNKAVDTA"
     gene            17324..17479
                     /locus_tag="TV188_000587"
     CDS             17324..17479
                     /locus_tag="TV188_000587"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533968.1"
                     /translation="MVTKFSEEIKIVRTKSSVYVNSVLDVADKKDPASVVAVAELLKA
                     YKSLTEL"
     gene            complement(17480..17683)
                     /locus_tag="TV188_000588"
     CDS             complement(17480..17683)
                     /locus_tag="TV188_000588"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533969.1"
                     /translation="MKRYIIEQLANETDTITIMFTNGKQHTFCQVANECPDNPNIIEL
                     KLSDAQYIVLVNLDQVTYISHHS"
     gene            17743..18204
                     /locus_tag="TV188_000589"
     CDS             17743..18204
                     /locus_tag="TV188_000589"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533970.1"
                     /translation="MQANRIFYGKEKPTNAVAGDCWFRDNELMILKDNWEASVNNLKS
                     PKVIGEIEIDLEQHDVLLTARGNRPPLLMIDGIMLGGVSKVIIINELSESCAIVSLNE
                     YIKENLFPFDDFESLQRLFQKGHQKLSVRELCLEKRLGEHSYQDHRKSCDE"
     gene            18346..19062
                     /locus_tag="TV188_000590"
     CDS             18346..19062
                     /locus_tag="TV188_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEL1533971.1"
                     /translation="MNQLINITLNENQEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKEVRKYFIQVEKDFNSP
                     EKIMARALLMADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQNGINI
                     GQNKLFQWLRTNGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNVTPKV
                     TGKGQQYFINKFLNQEYLPV"
     gene            19096..19245
                     /locus_tag="TV188_000591"
     CDS             19096..19245
                     /locus_tag="TV188_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533972.1"
                     /translation="MPEDLIKQLEAGSEFLAKTCLHSKIIITVDGVRLVETKEFHPVS
                     GTLLD"
     gene            complement(19242..19442)
                     /locus_tag="TV188_000592"
     CDS             complement(19242..19442)
                     /locus_tag="TV188_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KTSC domain-containing protein"
                     /protein_id="HEL1533973.1"
                     /translation="MQRQYVSSSNVRSVGWENNTLEVEFNNGSIYHYHNVSQTEYRSV
                     LVGSVGSNIHRLAKIHTYTRIV"
     gene            19553..19837
                     /locus_tag="TV188_000593"
     CDS             19553..19837
                     /locus_tag="TV188_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1533974.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKIKVIGMLNNETEIYPLELNKKQIS
                     KMLGVDPKTFDVRFNSHKDFPRIETGGREKYPRDLVIEWYSKNWERTGIR"
     gene            19834..19980
                     /locus_tag="TV188_000594"
     CDS             19834..19980
                     /locus_tag="TV188_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533975.1"
                     /translation="MIKKLFNFIFAKPKEESRQPYQQPRGFLDFETGKRIEIDPITRK
                     EYFV"
     gene            20184..20429
                     /locus_tag="TV188_000595"
     CDS             20184..20429
                     /locus_tag="TV188_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEL1533976.1"
                     /translation="MLLTILSNSDEWRVYPEELAKRCRDSVDAVRTQLKALEKAGYIR
                     SYRKSLGGRYGTETHRFCSDTKISDEVFQELLKELNC"
     gene            20591..20974
                     /locus_tag="TV188_000596"
     CDS             20591..20974
                     /locus_tag="TV188_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1533977.1"
                     /translation="MDEKKLFENFQLTFGRMISPFEIEDIQKWIHQDNMPIDVVNLAL
                     REAVENNKINWKYINKILVEWHKAGDTTIEKVKERLQRFEDSKEQRHATISNVPSWSN
                     PDYQGPTYDDLKVNPSEVSDGAGDF"
     gene            20955..21188
                     /locus_tag="TV188_000597"
     CDS             20955..21188
                     /locus_tag="TV188_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533978.1"
                     /translation="MAQEIFDGFNALINKMYGRQSSIETFNRFVEYCQKRREENGVEP
                     VLNPINLFAFGVGITTEEANKLRIKRYKQENGL"
     gene            21185..21325
                     /locus_tag="TV188_000598"
     CDS             21185..21325
                     /locus_tag="TV188_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533979.1"
                     /translation="MTKQYRETLIWHRASHKEREKLLDFGLVDKSQYMTLLRQLRKKY
                     AI"
     gene            21334..21540
                     /locus_tag="TV188_000599"
     CDS             21334..21540
                     /locus_tag="TV188_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533980.1"
                     /translation="MTPEQVEKAKIRAKRELETFSIYLDQAIVEYGSTLSPQEVFLAA
                     GFAYLGAGQTDIHAAIEGLYEQIQ"
     gene            21675..22403
                     /locus_tag="TV188_000600"
                     /pseudo
     CDS             21675..22403
                     /locus_tag="TV188_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017827951.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
     gene            22580..23791
                     /locus_tag="TV188_000601"
     CDS             22580..23791
                     /locus_tag="TV188_000601"
                     /inference="COORDINATES: protein motif:HMM:NF018751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEL1533981.1"
                     /translation="MSENLTLFENLNDIKPAEPAELSFDFEFTPAEIKIKGKEKLEEI
                     LAAYAKKYDGYTVTAETFEDDAKVRAKLNTLQKDINNSVKTKLAEYNNPLDDVKQWVN
                     SIIEPIKKITKTIDEGVKHFEEIERQKRANTIKETFEAAIAETGADIDIRLFESNFDD
                     MSAKGYFMADNVRVNTATKKAINKLVAEEVAKKQEHEQALIQISEAAAKADFGPAIYI
                     KRFENGAQLADILQAIADDKLLADKVREEEKRKAELSKRVEEMTALAQREGLQPGKYV
                     KLLEDGKSALVVFETLMDDSKKMQAKIAQKNAEAHQQQIEQTEYMSEASNSGVNELET
                     DKVINNIIKQENALEAKIEPNKSVTKWQGDFKITFPDSETAKLFGGQGGLYEKHGVIV
                     EKLGEWVKIND"
     gene            23784..24620
                     /locus_tag="TV188_000602"
     CDS             23784..24620
                     /locus_tag="TV188_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL1533982.1"
                     /translation="MTKLTEENYYQDREWLSNSRFKAFLDCEAKALAVENNEWEDTRD
                     ETPLLVGNYLHSYFESPEAHEKFKAENGAKMISSRGVTKGELKKEYKVAQNMIETLET
                     DEIFNLMYHGQSGDNVLKEMIIYGEILGIKVKGKVDSINLTKGYFCDLKTMKSIHSDE
                     WSNDLRKRVPGVAANIIGFKYHIQMGLYQELLRQMTGKTLQPLIIAISKENVPDKELI
                     ELGQTWLDEGLQLFENNVEHVHEVIIGKAEAKSCGRCDYCRSQKKLNRVVDLDDLIAG
                     IF"
     gene            24805..25146
                     /locus_tag="TV188_000603"
     CDS             24805..25146
                     /locus_tag="TV188_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533983.1"
                     /translation="MEQIKITGTDTILILDRVDRAFVIEGNLAERWRFTSKFIKIDDE
                     LSLDEDGELFEIVYDLMLEAKPHNVINLTSSYFAKEHKKDTDEIIKVFAFIEDNKKNI
                     FETLGIRGVLE"
     gene            25143..25655
                     /locus_tag="TV188_000604"
     CDS             25143..25655
                     /locus_tag="TV188_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533984.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLIQSGVLKHKSDSYFERGRY
                     MASKLRLIQSRALKKYDCSFSTIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVV
                     FINVSTWRKHWKFSYKDRSKKAMKAQSKAKAAENFGKIVKDDEADAVLIGAYYVNQGY
                     LDGLETHDYY"
     gene            25877..26104
                     /locus_tag="TV188_000605"
     CDS             25877..26104
                     /locus_tag="TV188_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533985.1"
                     /translation="MTKNDFLTGFVLILLAACIFAAGFVIGSDCSSEHYEQQMTGLRM
                     QLVNTQQQLKRASEDRARRTKRIADLTGNGG"
     gene            26108..26530
                     /locus_tag="TV188_000606"
     CDS             26108..26530
                     /locus_tag="TV188_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1533986.1"
                     /translation="MIDEIELDLQKPEIPQFVADYIDDMHKNARTLRYAFKYMESNIK
                     MHKWCVFERQETFVNAFLYGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFS
                     EIIDTDFYSREDVRLTESEIRKDFDWAWREGFAKEVTE"
     gene            26698..26928
                     /locus_tag="TV188_000607"
     CDS             26698..26928
                     /locus_tag="TV188_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003077369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533987.1"
                     /translation="MAYLREERETVIHYDELDDCWTFETNVRRHITKIEKRIELYEIL
                     SEEFDDRGRRIYICAKMKTGTVSPFAKPPRRK"
     gene            27305..27739
                     /locus_tag="TV188_000608"
     CDS             27305..27739
                     /locus_tag="TV188_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HEL1533988.1"
                     /translation="MTFFPEIDIQKTKSNAKRKLKEYPRWRRIANDVDTQKVTATYSF
                     EPRQPHGVHSKPVERLALNRVSAEQELDAIEQAVSMILEPERRRILYDKYLSPYKKAD
                     KVIYTELCMSESFYYDTLDIALLAFAELYREGSLIVEQGVFS"
     gene            28277..28351
                     /locus_tag="TV188_000609"
     tRNA            28277..28351
                     /locus_tag="TV188_000609"
                     /product="tRNA-OTHER"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
     gene            28510..29001
                     /locus_tag="TV188_000610"
     CDS             28510..29001
                     /locus_tag="TV188_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1533989.1"
                     /translation="MAKLTIKQQKFIDEYIICGNATEAALKAGYSKKTAGQIGEQNLK
                     KLEIKSAINERLKQLESSKIASAIEILQVLTAVLRQDLTEEVVTLNPVTGEYVTMQKK
                     PSIAEVIKAAGELLKRYPIQEQIEKIKQENELLRLKIETVKGAKPDTHLMEKLLEVIE
                     DGG"
     gene            29036..30289
                     /locus_tag="TV188_000611"
     CDS             29036..30289
                     /locus_tag="TV188_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1533990.1"
                     /translation="MRRPFNYELEVNEGTPRSGKTTAGHFRYARYLIESEDENHLVTA
                     YNQEQAYRLFIDGDGTGLMHIFDGNCEIKHDERGDHLLVTTPKGNKRVYYKGGGKVNS
                     VGAITGMSLGSVVFCEINLLHMDFIQECFRRTWAAKLRYHLADLNPPAPQHPVIKDVF
                     DVQNTRWTHWTMDDNPILTAERKQNIINSLKKNPYLYKRDVLGQRVMPQGVIYGLFDM
                     EKNVLDTLIGEPVEMYFCADGGQSDATSMSCNIVTRVRDNGKISFRLNRTAHYYHSGA
                     DTGQVKAMSTYARELKAFIDWCVKKYQLRYSDVFIDPACKALREELHAIGILTTGAPN
                     NAHDVNSKAKGIEVGIERGQTLISDGDFYLVNHKEEKYDHYHFLKELGLYSRDDKGKP
                     IDANNHSMDEFRYSVNVFVGRYKMK"
     gene            30299..31798
                     /locus_tag="TV188_000612"
     CDS             30299..31798
                     /locus_tag="TV188_000612"
                     /inference="COORDINATES: protein motif:HMM:TIGR01542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1533991.1"
                     /translation="MFRNLWTKIKGVMQKMGLIKGLKDLNLHREIELSDKHYDSIQIW
                     KELYQGYHDKIHDYYEKSILDGRKKKKRLTLNMPKVVTSELATLIFNEKCEINIGSEN
                     ESLTKLITETLEKNNFTQEFQRFLEYSFALGGMAIKAYLKKDGTIGLNFVQADSFIPI
                     SWDNAGISEAVFVDTQHRGKYKYTHLEWHTWESELYVVAHELFRTDKSNDDVGIRVPI
                     TEIYPDLKSQVVIEKLSRPLFVYLKPNSANNIDLSSPLGISIYHNSFDTLRAIDIAYD
                     SFEREFRLGRKRILVPATAIRTVVDSEGNFHRYFDATDETYEAFHTGEDSKIQDIKDI
                     SVELRVDEHIAAINALLNLLSMQIGFSPGSFSFDGVSGVKTATEVISENSKTFRTKQS
                     HETMVEATLKNLVAIIVDFGDLYGLIEGESKYNVTVTFDDSIAQDRTQDAQYYIGLVA
                     AGLISKKKAMMKLFNLSEEDAELEIQTIHEESRTTNDMSIDLFGLDGDA"
     gene            31798..33408
                     /locus_tag="TV188_000613"
     CDS             31798..33408
                     /locus_tag="TV188_000613"
                     /inference="COORDINATES: protein motif:HMM:NF017919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533992.1"
                     /translation="MDYDTHIQLSFDLIELYSDVERELLTSIGRRFAKHYDEMVAGDI
                     MDWQIRQLLEVGELRKEHIEIMRKSARVSRERMIEMLTEAGYTSAGRYEDFFKEAYVK
                     GLIKLNPSAADNSMRLLRVLNTYINQAEDTLNLVNTTMLQSGQDTFLDTVNQVVAYVS
                     TGIKTPQVAMRDALKNAGQKGLTVFRAKNGAQWSTETYLNMITRTMNSNISNAMEDER
                     RHEYGVDYIEVSSHAGARPRCAPYQGRIYYDGVGDDPLEKYPHFSETSYGEAAGLFGV
                     NCGHHKYPYVPGMSKQTFFPYSKSENDKTYAESQVQRKLEREVKQLKRERAILTAAKD
                     KEGAKLASQRLENKWQELRQFTAQTGRTRRYDREKSLNTILSEDKKKAIVKDNLKIRD
                     EYRAIKKAIPEVAPKNLETYYDMRYNGGKIYEDLVRDYKDYIRWSKAEFPTKKSFEGH
                     IDSHLKEFPGLTGKQYQKKAADLLSRPITDNILGYDTDSRRVRYDLENNIFALGRVKQ
                     GTITTMLKPKEGVDYFDNDWKREFDNLK"
     gene            33374..33595
                     /locus_tag="TV188_000614"
     CDS             33374..33595
                     /locus_tag="TV188_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533993.1"
                     /translation="MTGKESLIILNDLEYVHCPVCGTLTEVYDICDTCKWQNTGETNI
                     DGGPNYITLEEARRRWANGEPLRNFFKDQ"
     gene            33647..33931
                     /locus_tag="TV188_000615"
     CDS             33647..33931
                     /locus_tag="TV188_000615"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533994.1"
                     /translation="MNKRIEKKRRTQMMLDRILRIVELMSQATDDNFAILEKRLEKAE
                     KRNEELMEIILVNVKEVNNRFDELEICQKIVEDDVAELKKAKKKGWFSRK"
     gene            34017..34256
                     /locus_tag="TV188_000616"
     CDS             34017..34256
                     /locus_tag="TV188_000616"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533995.1"
                     /translation="MAVIIVQTRGGDIEVPTPLPAMQANKAIQSQLFDKELTFLCVDN
                     HAFAKTEVLHVLVETEEDEELPQSKHKEEETCYMD"
     gene            34241..34843
                     /locus_tag="TV188_000617"
     CDS             34241..34843
                     /locus_tag="TV188_000617"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533996.1"
                     /translation="MLHGLKHRLFKLAPDTGAGGGAEVTSETNAEAGRVEQTVSQQQA
                     DPVDTEAIKNQAINEVLSQLGVSSVEDAKANLASWNEYQEGQKTEFQKIQDSLTVANN
                     SLAERDTMIASLQAQLAAAQMGVPAENTSDVITLANSLVHDKTDINAAITTVLEKYPH
                     FKGGDADVADKPNFVTQTQSQTETTEDAFFKALGLTIKED"
     gene            34845..35717
                     /locus_tag="TV188_000618"
     CDS             34845..35717
                     /locus_tag="TV188_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003039217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533997.1"
                     /translation="MSINYITKHEGIFEKKLMQGALTSNLETPKVNWLGAKSFELPTI
                     SVTGYKAHTRSKGYNAGTVSNDKNTYTLGFDRDVEFFVDKADVDETNQELSMANISNT
                     FITEHATPEVDAYRFSKIATNAIDNSHFKQEDDYSTTNVYERLKAAILPIRKYGAGNI
                     IIYVSSEIMDFLERSKDFTRSIATTSPQGIDTRVTSLDGVQLIEVWDDARFKTKFDFT
                     TGFVKDGSGKDINFLIVAKPAVIAKAKFNSIYLFAPGQHTEGDGYLYQNRLYHDLFVL
                     KSKQDGVYVSHKSA"
     gene            35728..35976
                     /locus_tag="TV188_000619"
     CDS             35728..35976
                     /locus_tag="TV188_000619"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533998.1"
                     /translation="MKTYEKDNQVYKVQEGSELEIQLIADGFKEIIEANEKETDITKM
                     KLDKLKAYAENEGIIIPEDIKKKEDVLAFIKEQQQRGE"
     gene            35979..36365
                     /locus_tag="TV188_000620"
     CDS             35979..36365
                     /locus_tag="TV188_000620"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1533999.1"
                     /translation="MLTFDFYNKGYCGSQLNEEKFGELSKRAERKILALIGLKKEQVK
                     NLPLDILEAVKMAVCAQIEYLNAIGVESAIGVTSVTQAKVGNFSYTDGKKATVSASVG
                     SVGVSPDVLDYLLPSGLLYKGVNTRW"
     gene            36359..36703
                     /locus_tag="TV188_000621"
     CDS             36359..36703
                     /locus_tag="TV188_000621"
                     /inference="COORDINATES: protein motif:HMM:NF022130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534000.1"
                     /translation="MVKEVKPIPKELLVDTVTYLAVGNKDSWGAETVVSTELSQVLVQ
                     PRSSIQRGQQNESNSYELLLFFDCVNSLPVDHQFKVDDKISYLGKEYRIASVEVLKAF
                     DQSPHHYEVMLE"
     gene            36700..37053
                     /locus_tag="TV188_000622"
     CDS             36700..37053
                     /locus_tag="TV188_000622"
                     /inference="COORDINATES: protein motif:HMM:NF022564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534001.1"
                     /translation="MIGFKVEVIFNASKLIAKSEASAKTARFALSGQIKKDSDKYIPA
                     REWNLRDSGRVTERSVSWHTPYARRLYYNPQYNFSKDKNPNAQGKWFEVAKANHAEHW
                     YELTKKAYGAEFRGD"
     gene            37056..37424
                     /locus_tag="TV188_000623"
     CDS             37056..37424
                     /locus_tag="TV188_000623"
                     /inference="COORDINATES: protein motif:HMM:NF024103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534002.1"
                     /translation="MTFIDFLLRKVQEVSGAEPVLGIMGNSDKVAIIPMAGNFDNRAL
                     DESKIRIFTFQVLAKSKKQQEAFLTTENLVNGLDGLSNEPFTGGYLIKLECTTTTNFV
                     EKDSDKNYLYTALFRAELGG"
     gene            37428..37925
                     /locus_tag="TV188_000624"
     CDS             37428..37925
                     /locus_tag="TV188_000624"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534003.1"
                     /translation="MAADKPTFYLQSEHKLEISEDGKTWMRLAGGISELEPDGNEEVS
                     QDAYLDGSESDVTGGQLVLALTGHRLVGDKAQDWIYARQFRYGGKRRGFTRWTLPGGK
                     TQFTFASTFANIKGPSGAANGKGEIEFEIHSNETLVPNKVVVEVTKTNKELASEALGL
                     ERQER"
     gene            37945..38352
                     /locus_tag="TV188_000625"
     CDS             37945..38352
                     /locus_tag="TV188_000625"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534004.1"
                     /translation="MVRQFEFKKTVEEIEIAGEIYLLPLDDDNLLRIQRDFISYGKEI
                     EELQKVEVEKGDPDDLADNHKQQLLVMKKVIESPFGEGSFEKLYEASGHSLMNMVDLL
                     DYLVELVAEKVEQNKARATKAKEKYYSSKRKKK"
     gene            38360..38977
                     /locus_tag="TV188_000626"
     CDS             38360..38977
                     /locus_tag="TV188_000626"
                     /inference="COORDINATES: protein motif:HMM:NF018553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534005.1"
                     /translation="MKLTETYEVLADAFEFGGHIVTVDLAFDVVLRVMELLADAEVND
                     YAKIVWTLDMLLPYFDRTELSFDEEFEIFEYILKTFIYEQEDGEDDSLGGMSQTKTMH
                     FEKDAELIFASFFQSYHLDLFEQQGKLHWRKFMSLLMNLHKDTPFKEVVSYRVMKVPN
                     KDEASEEYIKHVKKMKRIYSLEDESEHQALNDDKLSALAARFGGE"
     gene            38978..41425
                     /locus_tag="TV188_000627"
     CDS             38978..41425
                     /locus_tag="TV188_000627"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1534006.1"
                     /translation="MADGSVIIDTLLKTEKFNQGVGKLQGKLAGLGSKLTSIGTGLTL
                     GLTAPIVGIGAASLSTFTTFESQMNRVKAISGATASEFRKLEDQAIKLGASSVFSATE
                     VAQAQEMMASAGFKVVDILKAMPGVMSLAAVSGGDMALASEAAATAVNMFGLEAKDAA
                     HVADVFAQAAADTNAEVGDMAEALKYAGPVAGALGISLEETAAAIGIMSNAGIKGSQA
                     GTTLRTSLSRLTDPTKKMRGIMSELGLEFFDVNGKMKSLSGITKELQTKMGDLTDSQK
                     SAAISTLFGKEAMSGMLALVNSAPGALDKQTQALINSNGAAKEMADTMNSGVKGSIEE
                     LKGSLETAGISIGKILAPALTSVIGAITSLVNWFNNLSPTMQNVVVVLGSLLAAIGPV
                     VLIIGVVTTQIAAFQQGVGLVFNAVKGLQAAFAFLTSPIGLVIVAIGALIAVFVYLWN
                     TNEQFRTKIIEIWTAISNFLQPIIQFIGNFIRETWTQLATFWNENQATIMTIAQTTWS
                     FIQTIFTTAIEMIKLAVSVFLGLLQSTWSVTFNSLKVIAQVAWAFISNVFKGSLGSIL
                     AVASAIFEQIKSTIDLAMKIIQNIIKIILSAIEGDWDGVLEGIKGIVSAFGDFIQSTF
                     SNMMDTAKRLVGAGIDTVKGIFDSLWNIDLFGAGQAIINGFLNGLRSMWGAVTDFVGG
                     IASWIAANKGPISYDRVLLKPHGKAIMDGLGNSMKTNFKDIQKDVSGMADDLTRSFQI
                     KRFNGFLPEKYTTKLDELKKYAQATLGGMILAPNMAVQPTVVVNISNEADSDIIRQKV
                     NAKNAQDAIINQLFKKG"
     gene            41429..42190
                     /locus_tag="TV188_000628"
     CDS             41429..42190
                     /locus_tag="TV188_000628"
                     /inference="COORDINATES: protein motif:HMM:NF017520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1534007.1"
                     /translation="MFSIEFLDGERLSADERGWKVKEMSSSGLEQNVVSESPKMRSGR
                     LVYGLYHGIKTYQLVFTKIIKDTLDYSRLVDEVNYYFLRDEPYYLYRDFRKKADRVDL
                     PKKRAKVFTKSIDHQKNGLKVEFTAKLESYELPYEEDTEVQRVTWTATHSWHNKGGHR
                     LDPRYCPMKMTITVSGSGAELKVLFNGQPYFWYKKSVKQGDIFIIDGTDVEKNRYNCF
                     EDCHKQTSFLKTGNNRIDIQGASCEALFEYRLLYL"
     gene            42201..>43765
                     /locus_tag="TV188_000629"
     CDS             42201..>43765
                     /locus_tag="TV188_000629"
                     /inference="COORDINATES: protein motif:HMM:NF018329.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1534008.1"
                     /translation="MQVKTKQGVFYVNADYTVVEKQGDYPKLTCTIPIKGNETWIADC
                     QELDRLYPAGEQDEFIIINPIKVTKGSSYDLEITAIGAFHFEFVKARLYEELPERMYT
                     LDYLLDLLFKDSRFSYKLQGDYSTRRFSGFGDDNKLTLFHHLMERFQTEFKVVGKVVL
                     VNTKVGKDTGFQFRYLRNIKDTKYSVDVTNLMTYVKGYGAWFDENDHSKGRLIVDYES
                     PLSKEYGKLDGKPVVDERMSLKESLIKKCKLAVDRSVSVSLTTTLVSLKQQDYQGAAR
                     IGDSIWFIDERISIEKKIRFSVVTTYYNAYDDILKQDVTLGDKDTYSRYQSLENSSQT
                     ETNDFQKAMSSKLAEVQDDVKKTHILVSGTTRIFFSTEFPQDNPKGTIKEDDILYRNH
                     DGTTLMYRWNGVQWELVPLVNDPDRWREELEKQISEAVEKLKQEQKVINQRTDKELEE
                     FRDTLKNLSLPEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTD
                     GKTRYNKNLLVGDP"
BASE COUNT        13652 a         7909 c         9661 g        12543 t
ORIGIN      
        1 tcagtcttta ttttttgtta tgtaaaaagt ataggtggtt atggccgaat agaaaactag
       61 ttttggagta aatgataagg ataagcgatt gaaacaatat gctattgctg tataaactga
      121 cattacaata ataaaataac aaatatagtt cttaagccca cgcatttata cgaccgttat
      181 ttgggtgata atctcgagca tcgacatatt gtgctagggc atatccgaca ttatagtaaa
      241 tgtttattac tgagaatgca gctctaagta aaccggaaat aaatccggtt agtacaccaa
      301 gtcgttgagc tgcagctttt gcagctcggc taagtacagc tcgagcggca gctactccat
      361 gtttggcaac gtactttccg atggttgcat atccactaat taacccgcct acaataacat
      421 caaaagccca agcgaattca tctaaggtta ctccttgccc gtcccataca ctagctctaa
      481 aagtgtatgg actcatggct ttatacgcaa tttcacgcat ttcttgttct gttaaatttg
      541 gataaagagc ttttttctct tggattaatg tatctaactc actttttgaa atttctagag
      601 gttgtgataa tttttcttca attacttttt cttcctgttg aattttagtc acttcactag
      661 catatacaat ggaaggtaca gtgttagcaa tgagtaataa ggacgctatc attgcgatga
      721 tcaattgttt tacttttttc attttgaatt tcctttctga aaacgatggt gatctactaa
      781 gggttaatta gctttactcc tttctaacca agatggtagt tatttgtcat ttaataagat
      841 atcttatagt ttcattatat tattaaaata ataaaacaca agtctttttt ggtaaccgtt
      901 ttcgtggtat aataaaagat taccagttaa ctattaagtc tgtaatcttg ttttaggctt
      961 atatctagag ttatcacatg ctgatgaggt caatcagttt ttttgattat ttggaacatt
     1021 tttgacggtt attactccaa agagctttag ctttggcttg gacttaggaa atcatgggga
     1081 caattgctta gcggcagaga tgggcttgtt tgctctttat tgatagttag gaggagctgg
     1141 tagcctgttt agattggcat cttgagccca agggctgttg atgatgttgg ataagaaatt
     1201 gtgcccaatg gggactagtt tattgtaacc gttttcgata gaatgaattt agaaaggaaa
     1261 tcaaatggtt gatagcaaag cagttgtcat tttgatgacg ttgatgactt atcaagactt
     1321 atcactttac gagctgagtg ttaagacaaa attcaccatt agagagatta aggaccgtat
     1381 tgatgagctg aatgagtttt tggctcagca tgagctctca gagctagatg caacaaggtc
     1441 tggctatcgg atcagtcagc agcttaaggc tgagtcagat catttgttta cgttgattaa
     1501 tgctgagcag gtttatcttt ctcaggcaga gcggatcaat cttatctatc tgtatacctt
     1561 ttgccgcagg gattttgttt caaatagtca ttatcaggac tttttaaagg tcagcaagaa
     1621 cacagccttg acagatatta aggccttgcg gcagaagctg gcagatgttg acttggaatt
     1681 aaagtatacc agagcaagcg gctatatctt agttggtgat gagattaata agcaccggtt
     1741 ggctttagta atgattgcta ctttgcttaa atctcctatt ggcttgtggg ccttggacta
     1801 tattttggct tcttggcact atcaggtgtc gtttgaagcg cttgaaaaac gtgtgagcca
     1861 tttttatcag acctttcaga tgtctccgat ccttgatcgt ctgcaggtct gtttgtacgc
     1921 tgtcatcttt attttatgtc gttaccaaag acgggttgat agggtcaagc aaagacaggt
     1981 agtggtttct gagcagctgg atcagctaac ggcccttttg gtggcagaaa taatgcagca
     2041 attgtctctt aagtatcagc tatttgaagc tgatgaggcc tattttcaat tgctgttagc
     2101 gggctgcttt gagggtgagg gtactgttgg tgatgatttc tttgaatcac taaccgttgc
     2161 gattgttgat caaatgcagg gggttgcttt actaagcttt agtcaggcag atcagctcaa
     2221 ggagaatttg aaaaggcatt tgattccagc ctattaccgt ttgcgctatg gtttgccaag
     2281 tgataatgat tataccttgc ggattaagga tagttattct gagctttttg acttggtaaa
     2341 gcagtctctg gagcctttag ccaaggagct gggtagtcct ataccagata gtgaaattgc
     2401 ttattttgtt cttcattttg gaggctattt aaagcagcag ggaagagatt ttcatcgtca
     2461 agcctatcag gctgtgattg tctgtcctaa tggtgttagt tcttctttaa tgatcaagga
     2521 gcatttaaag cttttatttc ctgatattgc ttttcggggg ctttcaaggc ttgatcagct
     2581 tgggcaatta gataagagcg gctatgattt ggttttttca acgatacgat tagagactga
     2641 taagcccttt tatttagtcc ctatgataat gactgatgag caggcttttc agctggtcag
     2701 cttggttaat cgtgattttc cagatattgg ctatcggcta gaggttgaag agctgctcca
     2761 tcttatcagc tcatatgcgg tcattcatca aaaagaaaag ctgcgctttg ctttgcagca
     2821 atatttaaga caaggtgtga aaagaaagga tattcgacca gtgttacaag acttaattac
     2881 caagaaaacc tatcaatcaa cctcagagca attggggtgg agagaggcta tttatttggc
     2941 ggctcagccc ttgttagaga gtgggcagat tcaagcgagc tacccggagg ctatgattgc
     3001 taaggttgag gagtttggta cttttattaa tctaggtaag gggattgcta tcccacatgc
     3061 gaggccagag gatggtgtga atcaggtagg tatgtcgatg cttgttttag agcacccgat
     3121 ttatttgtta gatgatccta agcaggagat tcgtttgtta atttgtattg ctgctattga
     3181 taatgaaaca catctaaagg ccctgtctcg gctgacgacc attttaagag acaatgagca
     3241 ggtcaaggct ttacttgcgt ctaaatcatt tgaggatatt aaaactatta ttgcagagga
     3301 ggcataaaat ggcattaaga attggtacag cctgtggttc aggcttaggg tctagcttta
     3361 tggttcagat gaatatcgaa tccgtattaa aggacttggg agtaaccggt gttgaggtgg
     3421 agcattatga tcttggtggc gcggatccca cagcggcaga tgtgtggatt gttgggcgtg
     3481 atttggcaga ctcggcagag catctgggag atgtgaggat tttaaatagt atcattgata
     3541 tggacgaatt gactagtctg gtaaaggcta tttgccagga aaaggggctt gtttagaagg
     3601 aggataagat gacattttta cttgatattg ttagcacacc agctattttg gttgccttga
     3661 ttgctattgt tggtctctta cttcaaaaaa agcctgctcc tgacattgtt aagggaggca
     3721 ttaagacctt tgttgggttt ttagtggttt caggtggtgc aggtatcgtg caaggctcac
     3781 tcaacccttt tggaacgatg tttgagcatg cctttcatct gtctggtgtt gtgccaaata
     3841 atgaggctat tgttgcagtt gctttgacga cctatgggtc agcgacagct ctgattatgt
     3901 ttacaggaat gatctttaat attttgattg ctcgctttac ccgatttaag tatatcttct
     3961 tgacagggca tcacacactt tacatggcct gtatgattgc tgtgattatg tctgttgcag
     4021 gcttgacgtc agtgtccttg attgtgtttg gtgggctggc cttagggatt atcatgagtg
     4081 tttcaccggc tcttgtgcaa cggtatatga tccagctgac tggtaacgat aaggtcgctt
     4141 tggggcattt tagctctctt ggttattggt taagcggttt tgtaggaggt cttgttggag
     4201 acaaaaccaa gtcaacagag gacattgatt ttccaaagag ccttgctttt ttgcgtgata
     4261 gtacagtaag cattacctta tcaatggcaa tcatttattt gattgtagct atttttgctg
     4321 gtcctacttg gattagtaag gaattatcct ctggcacaca tggcttggtc tttgccttgc
     4381 agttggcagg acagtttgct gcaggcgtct ttgtgatttt agctggtgtt cgtttgattc
     4441 tgggtgaaat tgttccagcc ttcaagggca tttctgaaaa attagtgcca cattctaagc
     4501 cggccttgga ttgcccgatt gcctatcctt atgcccccaa tgcagtgctg attggctttg
     4561 tttctagctt tgttggtggc cttgtgagca tggctgtgat gatcgtaagt ggaacgacag
     4621 tgattttacc tggcgttgtg cctcatttct tctgtggtgc cacagctggt gttattggga
     4681 atgcttctgg aggtgtgcgc ggtgcaactg tgggagcctt tttacagggt gttcttatta
     4741 gctatcttcc gattttcttg atgcctgttt taggcggctt gggctttgag ggctcaacct
     4801 tctcagatgc cgattttggc ttatcaggta ttttactagg aacacttaac agcataggtg
     4861 gtgtgacagc tattgtgatt ggtatttttg tgatattagc tggacttgtt gggctttctg
     4921 ttgttggaaa atcagtagct aaggaggaat aagcatggtt ttgagtgatg agcctctaac
     4981 agatgtgaag cgattcgcag cagagattcg tctaaatacc ttggagactc ttaatcatct
     5041 tggctttggt cattatggcg gtagcttgtc tattgtagaa ttgctggctg tgctttatgg
     5101 agaaatcatg cccatgacac cagagctctt tgtccagtca gatagagatt atctggtgtt
     5161 atcaaaggga catgcgggtc ctgccctcta tagcactctc tacttaaagg ggttttttga
     5221 taaggccttt ttacagtctc ttaataccaa tggaacaagt ctgccctcgc acccagatcg
     5281 tctgttaacg cctggtattg acatgacgac aggctctctt ggtcagggaa ttagcgtagc
     5341 aacgggcatt gcctatgctc aagcgcttga gcagtcacca cattatacct atgcaatcgt
     5401 tggtgatggg gaattaaacg agggccaatg ctgggaggct atccagcttg cggcacacca
     5461 gcagctaagt catttcattg tctttgttga tgacaataag aagcaattag atggaacaac
     5521 cgaggcaatc tgtcgtccag gtgattttgt tgaaaagttt acggcatttg gctttgaaag
     5581 cttacgtgta gatggtaggg atgttcaggc tatttttgaa gccatcaggg ctttgcaggc
     5641 gtcatcaagt cataagccca agtgtatcgt cttagatacc gtcaagggtc agggtgttag
     5701 ccagctagag tcaatggcag ctaaccacca tctaagacca acagcagccg aaaaggagat
     5761 gcttgctgcc gctgtcagaa agctacgagc tagtttggag gtgacaagat gactcgagca
     5821 agtcaagaaa tgcgtcatgt ttaccgagat ttcctcattg cagccaacca agagcaccct
     5881 gaggtagtcg tcttagaggc agatttatca agctcaatgg ccaccaacca tttggatcag
     5941 gtgtttggca agcgctatat taatgtaggc attatggaag cagaaatggt cggtctggca
     6001 gcaggcctgg cgattaaagg ctataagcct tacctacaca cctttggtcc ctttgcctca
     6061 cgtcgtgtgt ttgatcagct gtttctttca ttagcctatg cccagctagg cgcaacggtt
     6121 attggctctg atgccggagt tagtgcggaa atgaatggcg gcacccatat gccctttgag
     6181 gatctgggac tgctgcgcct gattccaagg gctattgttt atgaggtcag tgatgacgtt
     6241 caatttaaag ctgttttaaa ggaaacccta tcactcgatg gcctaaaata cattcgaacc
     6301 attcgtaaaa agccagaggc tatttatcaa gggcatgagg acttttctaa tggctattgc
     6361 ctattgcgtc aaggaaaaga ccttgtgctg gcttgctcag ggatcatggt caaaaggtgc
     6421 ttagaggtag ccgataaaat ggcagagcag ggctactcta tcggtgtgat tgatgttttc
     6481 agggtaaagc cactggccga tgagctaaag ggtctactta caggcagtcc tgttctaacc
     6541 gttgaaaatc ataatcgtat cggtgggctt gggagtgcta tctgtgagct actggctcag
     6601 gaaagtaata ctccagttta ccgtatgggg gtggacgaac gtttcggtca ggtcggacag
     6661 atggattatc tattagagga ataccagctg acgccagcag ctattgagca gcaggttttg
     6721 aggattttag cggcagatta gctaaaaaag cctatcaggt gtaccacacc caaaaagctg
     6781 gaccttatag attaggattg agctttgtat gaaacagggt tcagtccttt tagttatgcg
     6841 ctttcagtcc ctttcactct gtaggcgtga aataatgatt gataactctt gatttcacct
     6901 tctaatttta atgtcataga aaaagttctt aagctttagg ttttatcttc acctttgggg
     6961 tgcaattctt ttgtcaggac tgatagggcc ttttgctatt actgctgagt ttttggcata
     7021 ttgtgagggc tgttttcatg aagctggaga agaatcgttt gatttcttag tgattgttca
     7081 gtttttatga ttaatcttac tgataaaagg accaaagcag ctaagcgttt actatctatg
     7141 ccatgcgata cgaagaatga gcttattttt gaacagaaag ttaatataaa acgagtattt
     7201 tgaacgattt tttggtaaaa tgtaagagat tacattatga ggagtaaaag ctagtcctaa
     7261 cataatggtt taatttaaaa aaggagcaat tcatgacaac atatcaagaa gatttttatc
     7321 aagccgtcaa tggtcaatgg gcagaaacag ctgttatccc agacgataag cctcgtacag
     7381 ggggcttttc agacctagca gatgagattg aggacttaat gctgaccaca acagatgctt
     7441 ggttggctgg tgagcatgtt cccaatgacg ctatattaga aaactttgtc aagtttcacc
     7501 gcttggttgc agattatgac aagcgtgatc aggtgggcgt agcgccagcc ttggacttaa
     7561 ttgaagaata caaggcctta ggatcttttg ccgagtttgc tagcaaggtg gctgattatg
     7621 agctaaatgg aaaaccaaat cagtttccat ttagtgtagc accagacttt atgaatgctc
     7681 agttaaatgt cctttgggca gaggcaccag gtcttatcct gccagatacc acttactatg
     7741 ccaaagacaa tgacaaaggc aaagagctgc ttgctatctg gcgtggcatg caagaggagc
     7801 tattgcctaa atttggcttt tcacatgaag aggttaagga cttgctggat aaggttatca
     7861 cgcttgataa acagctggca gattatgtcc tttctcgtga ggaatattca gagtatgcca
     7921 agctttacca cccttatgac tgggccgagt ttaccaagct agtgccagaa ttgcctttag
     7981 ataatatatt tactgtgatt ttaggtgaag taccagacaa ggttgttgtg ccagaggagc
     8041 ggttctggac agaatttgca gctgactatt attctgagaa gaattgggag ctgctaaaag
     8101 cctggctagt gcttacagca gcaggtgctt atcatgctta tttgactgac gagattcgtg
     8161 tgctatcagg agtttacagt cgtgccttgt caggaactcc acaggctatg gacaagaaaa
     8221 aagcagccta ttacttagca caaggaccat ttaatcaagc tcttgggctt tggtatgctg
     8281 gtgaaaaatt ttcaccagag gctaaggctg atgttgaaca caaggtagct aagatgattg
     8341 aggtttataa atctcgtctt gaaactgcgg attggcttgc accagcaaca cgtgagaaag
     8401 ccattacaaa gctaaatgtt atcaccccac acattggcta tccggaaaaa ttaccagaaa
     8461 cctatgctaa aaaggtcatc gatgataagc tatcacttgt tgaaaatgct cagaatttag
     8521 ccaaaatttc aattgctcat tcatggagca agtggaataa gcctgtggat cgtagtgaat
     8581 ggcacatgcc tgccaacatg gttaatgctt attatgaccc acagcaaaac caaattgtgt
     8641 tcccagcagc tattctgcag gcgccgtttt attcgttgag tcaaagctca tcagctaatt
     8701 atggtggtat cggtgctgtt attgctcatg aaatttcgca tgcctttgat accaacggtg
     8761 cttcctttga tgagcatggt agcctaaaga attggtggac agacgaggat tatgccgcct
     8821 tcaaggagcg taccgataaa attgtagagc aatttgatgg ccttgactcc tatggtgcta
     8881 aagtcaatgg taaattaaca gtgtctgaaa atgttgctga cctaggtggt gttgcctgtg
     8941 ccttagaggc agctcagtca gagccagatt tttctgccag agatttcttt atcaactttg
     9001 ccaccatctg gcgtatgaag gcgcgtgagg aattcatgca aatgatggca agtattgacg
     9061 tccacgcacc tggtcaatgg cgtactaatg tgaccttgac aaactttgat gaattccacc
     9121 aagaatttaa cattaaagaa ggtgatccaa tgtggcgtgc tccagaggat cgtgtgatta
     9181 tttggtaatc attgctcatt aaaaaaagac taagaggctt tgtacggccc tcctatcgtt
     9241 agaacgtata gtctagcttg tggaggaagg catgcttctc ttagtctttt tgtgttggat
     9301 aggctcgaaa agctcttttt ttaggcgtaa aaaaagattg aagatagctc ttaaaagctg
     9361 tcctcaatct tatgacttat gattagacta gttgttaagc gcagctgcca ttgtagcagc
     9421 aacctctgat tcaaagtcgt tagctttttt ctcaatacct tcaccgactt caaagcgagc
     9481 aaagctaatc gctttagcat tgactgagtc aaggtatgct tcaaccgttt tgctgtcgtc
     9541 catgatgtaa acctgagcaa gaagagtata ggcttggtca accttagtgt tatcaagcat
     9601 gaagcgatcc atcttacctg ggataatttt gtcccagatc ttttcaggct taccttcagc
     9661 agcaagctca gccttgatgt cttcttcagc ttgcgcaatc acgtcagctg ataattgagc
     9721 ctttgaacca tatttcaaga atggaagtgc tggcttgtta accattgcac gtgattcatt
     9781 gtcaagctca atagcgtggt tcaattgtgc caactcgtcc ttgataaatt gtgggtcaag
     9841 ctcagtgtat gataaaacag ttggcttcat agctgcgacg tgcattgata cttgcttggc
     9901 aagtgcttcg tctccgcctt caacaacagt gataacgcca atacggccgc cattgtgttg
     9961 gtaagcgcca aagtgttggt catcagtttt ttcaactagg gcaaagcgac ggaatgagat
    10021 tttttcaccg attgtagctg ttgcattgac ataagcatca gcaagtgttt caccagaagg
    10081 catgataaga gcaagtgctt cgtcgttatt agctggctta ccttctgcga tagcctttgc
    10141 agttgcgttt accaattcaa cgaattgagc gtttttggca acgaagtcag tttcagcatt
    10201 gacctcaaca acagcagcaa cgttaccatt aacataaaca cctgtcaagc cttcagcagc
    10261 aacgcggtca gcttttttag cggcctttgc catacccttt tcacgaagaa gctcaatagc
    10321 cttttccatg tcgccatctg tttcaacaag tgctttttta gcgtccataa cgccggcacc
    10381 agatttttca cgcaattctt ttacaagctt agctgtaatt tctgccattt ttatttcctc
    10441 caaaattaga atcggtcctc ttaaagctcg ctttagcaga gcctttgacc tgctgggttt
    10501 tcttacttaa aaaataacga gatagagcgg aatgctttgc cccgttagac catgttatga
    10561 atagcaagaa gctatcctag ttcaataagc ctgacttaag cttcgtttga accttcaaca
    10621 acctcaacga tttcttcgat tgactctgct tgagtatcag cttcaaatgc aacctctgcg
    10681 tcttcacctt gacggccttc gataacagca tcagccaatt tagcagtgat taatttgaca
    10741 gcgcggatag cgtcgtcgtt agctggaatg atcacatcaa tgtcatctgg gtcagcattt
    10801 gtatcaacca ttgccacaac tggaatacca agcttcttag cttctttaac agcgatttgt
    10861 tctttgtgtg ggtcaacaac gtacatcaca tctgggatac gaggcatatc ctcaatacca
    10921 cctaagaatt tttcaagacg tgcgcgttgc ttgttaagaa gtgcaacctc tttcttagga
    10981 agaacctcaa aggttccttc ttcttccatg cgtttgattt ctttcaaacg agcgatacgc
    11041 ttttggatag ttccccagtt tgtaagagtt ccacccaacc agcggtggtt gatgaagtat
    11101 tgacctgcac gagtagcttc gtcagcaact gcttcagcag cttgcttttt agtaccaaca
    11161 aacaagataa cagcgtcatt agctgctgca tcacgaacaa actcgtaagc ttgatcagct
    11221 aattttacag tttgttgcaa gtcgataacg tggataccgt tacgctctgt gaagatgtat
    11281 ttagccatct tagggttcca gcgacgagtt tggtgaccaa agtgaacacc agcctcaaga
    11341 agttgtttca ttgaaattac tgccatgagt agtttctcct ttatagaaat gtttttttcc
    11401 tctcttagac gtcggcttgc aactccacct gatggcaaca gaatcacaat cgatctaaga
    11461 tgagtatttg ttgtctgcac aactacaaca gtataccaaa aaaagctagt catagcaagc
    11521 ctaaatacac taaaacccac gtcgtacgca tgaggaaaat gcatgccatt attttctaac
    11581 catatgcatg ttttcaatgc atttttgata tgttgacgtt ttgacacgat ccatttttca
    11641 agcgcagctt agttttacta tcaatctttc tgaaaaagaa cacatgaatc atgaaaagat
    11701 atcagagaac ataagtttct tcaagcattt ggcgtacccc aaatgcttga tctatcagcc
    11761 ttgctgttta ttaggcctct aaaaagcaaa aaccagggta aacagttacc ttggtttttt
    11821 gctaacttac tgacgaatca ggtaatcaaa tgctccaata gcagcagtag cacctgaccc
    11881 catagaaata ataatttgtt tgtaggctga atctgtacag tcgcctgcgg caaagatacc
    11941 tggaatattg gttgaaccat atttatcaac aataatctcg ccacgatcgg ttaagctgat
    12001 accgctgtct ttgagccaag ctgtatttgg caccaagcca atctgtacaa agactccttc
    12061 aaggtcaaga tgcttttctt gattgctgtc acgctcgata tagttaagcc ctgtgacatg
    12121 atcgtcccca acaatatcct ttgtagcaac attttttaga atagtcatat tgtctgtttt
    12181 agcagcgcga tcctgtagca ccttgtcggc cttaagctca ggtaagaact caagaacata
    12241 gacatgctta gctaagccag ctaaatcaag tgcagcctca agtccagagt taccaccacc
    12301 gataacagca acgtttttat cttcaaagag aggaccgtca cagtgtgggc agtaggttac
    12361 tcctttattt ttaaactcat tttcgccagg aacattgata ctgcgccatt ttgcaccaag
    12421 cgctagaata gctgttttag ccttcaagac agcgccatta gcaagagtaa cctcaacaag
    12481 gtcttttttc tcaatcgaag tagccagctg ggctttgatg atgtcaacat cataggattt
    12541 agtatgctcc tcaacctggg ccataagctt tggtccctct gtatacaggg ttcctatcat
    12601 gttttcgata cctacagttt ccatgacttg accaccaaag gtctcagcca aaagacctgt
    12661 atttaagcct ttacgagcag catagatggc agcactattt cctgcaggtc ctccaccaat
    12721 gacaaggacg tcatagactc ctttatcagc aaaggcctcc ttagatagag gtcctgcgat
    12781 ttgctcaagc agctgctcaa tagtggcgcg accagaggtg aattcttctc cattcaaaaa
    12841 gacagttggc acagacatga tgccctttgc cttgacttcc tcttggaaca taccaccctc
    12901 aaccatagta tgtgaaatgt tcttattaag aacagccata atgttcaagg cttggaccac
    12961 atctgggcaa ttatgacacg ttaagctgac ataggtttca aagcttaaag gacggtcaat
    13021 agccctgatg cggtcaataa tatcctgctc aatctttggt gcacgtcctg aaacctgtaa
    13081 tagagcaagg ataaaggagg caaactcgtg acctagaggc agtccagcaa agatcactcc
    13141 gctgtcttga cctttttggg taatcttaaa gcttggttga cgtgttaggg tagtctcctc
    13201 aacagtgata cggtctgaca tggcagcaat ttcttcaatg aagtccttga ccttttgtga
    13261 gctatcgtca ctaccaagat aagcttgtag gactaagtca gattccaaaa gattaaggta
    13321 ttgagcaagc tgctctttaa tatcaggact taatgccata gcttttctcc tttgcctgct
    13381 taaattttgc cgacaaggtc aaggctaggt gttagtgttt cagccccttc tttccatttg
    13441 gctgggcata cttcacctgg gtgcttacga acgtactgag cagcacgaat cttatcaatc
    13501 aagctgcttg catcacgtcc gataccatca gcattgattt ccatcatttg gataacacca
    13561 tctggatcaa taatgaaagt accgcgttga gcaagtccat cctcaccaag aacatcaaag
    13621 gcttgtgaaa tagcatgtga tgggtcacca atcattgggt aagtgattgt tccgacaaca
    13681 tctgaatcat cgtgccatgc cttatgaaca aagtgtgtat cagtagatac agaataaacc
    13741 tcaacaccta aagattttag tatttcatat tgctcttgaa ggtcacctag ctctgttggg
    13801 caaacaaaag aaaagtctgc tgggtagaag caaacaactg cccatttccc tttaagatcc
    13861 tcattagtta cagtgataaa ttttccattg tgaaaagctt gggctgaaaa ttcagcaatt
    13921 tcctttccta ctaaagacat gtcatgtcct ccttttttac atttgatacc tgtattataa
    13981 gctaagaaat cttatctgtc cacttgtaaa ccctagattt atcaaggttt ttgatgttct
    14041 tttctaacaa tttcatatgt gaatttagtc acactgttta aaactattct aaataataga
    14101 aaactctgat aatatcaaag attcttgaaa ataagttttt gaaataattt taatattatt
    14161 aaaaatgatt ttctgattta aactctaaaa aataacataa accgaaaaaa ggagcagcct
    14221 gctaaaaaat agctgctatt tttatcttga cgaatgctat caactagggt aaaatagttc
    14281 ttgttatggc ggtatagcca agtggtaagg cacggctctg caaaagcttg atcgtcggtt
    14341 caaatccgtc taccgccttt tatatacaaa cgaatccttg attaacctcg taaaaacgtt
    14401 gttaaatcaa ggtttttatt ttttgtggca ggataaaaaa agagaaaaaa agaaataaag
    14461 tcggtcaaaa gtcggtcaaa tttccaaaaa tatcttttat ggcctgattg ttcttttctt
    14521 ttagcttatc tagctgatgg gcatatacct taagcgtaat gttcaaattc tcatgcccaa
    14581 gcaactgaga tatggatatt aggtcaacac cctttaagat taaaaaagat gcgtaagtat
    14641 gacgtagaga gtgattgcgt acaggacgac caacaatttt tttaaccaat ctattgcaga
    14701 gtgaattaga agctccgtag agcaccctat ttagcttatt ttcattataa taattttctt
    14761 taaatgctct aagcaatttt atagtttgct gatcaatggg aatttgtctt tttgattgct
    14821 cgttttttgt ttccttaaat tcttgagttt ttgagtaatc aaacgattta ttaatatcta
    14881 taaatccctt ctcaaagtct atatcgctcc aagttatccc ggtcgcttcg gcgaatcgta
    14941 gtccagtcac tgctatgatg tataaagtaa aataggaaac atactggtat ttctcactcg
    15001 ttactttgat tagatttaga tattcatctt cttcaaggaa atcaaattct tttgctctag
    15061 cttctttttg agattttaca atcgcacctt cggcaaaatt tgttttgata agcccatctc
    15121 taactgctac attaacagct ccttttattt gatagtggag tttttcgagt gtttcttggg
    15181 catatttttt ggcaaattcg ttgattgttt tttggtaaaa ggtatgcgtt acattattaa
    15241 gcttaatatc accaaaatat tttttgatgt gcttaagatt tttagtgtaa gtttcccaag
    15301 ttttatcgac aacatgcgga cgtttgtaga ttttagccca ttccttgcaa aaatcataaa
    15361 gtgatatatc atcaatatct ttatttagct cagcctcgac tttaatcgca gctgcagaag
    15421 ccaatgcttt tgtcttaaaa ccacctttgg atttttccct tttgttcccc tgactatctg
    15481 tgtagtaaat acgataagac cacttgtcgc cgcgttttct aaattttgcc attgttaatt
    15541 acctcatttt tatgttaaaa tgggtacagt aaagagacct actgcgaagc aggtttttta
    15601 ctatacagga tttgcctcac gctcagactc gccaaagttt gagagcgtgg ggcttttttt
    15661 aacgtttgat tttatagact gagcttcgat gctctatttt aaaaacttcg atgacaactt
    15721 cgtcatcaat aatctcagct aaaatacgat agtttcctaa acgataacgc cactctcctg
    15781 tacgattagc ttgtaaagct tttccgtatc tccttgggtt atctgtgcca tcaaggttag
    15841 tcattatcca ctgatagagt tgtttagcag tagatctatc taattttttg agttgttttt
    15901 tggctttttt agtaaacaat actttataac gcaaaaccta gctccttcgc tacatcttcc
    15961 atgctaaatc gtgtcccatc gtcctcagcc ttagcttttc tcaattcgta caaatcttta
    16021 gcatcttcaa tgatttccaa aaactggtca actgttagat tggaggtgtc aatgttattt
    16081 tctttgatgt aatctgcgat ataagcatcg tctttttcaa ggtttaatgt cattgcaatc
    16141 atagtatttt tctccttcta tatttctact ggtgtaaagc tgccgacgac atcatagatt
    16201 ttgatgtaag tatcttctgc tggcgggtag tcgataaaga tatcattgta ttttttattg
    16261 agagatacta atctaagccc gtcttcctct gtgtatactt ttttaaaata ggtctgtccg
    16321 ttatgcacaa ctatacatag ctgaccggca tatgctgaca tgccccgatc tacaatatag
    16381 agcatatctc cttgctcgta ctttggtagc atactatcgc cccgcactcc aattgcatag
    16441 tcgtagtgag gtggttcttc gtcagtgtag acagtatatg tgtcatattc atctgcttca
    16501 aatccacgac caaagccact tgcggctgcc gcgtaagtta cgccttgaac cgaaaataat
    16561 tcttcatgcg tagaaacaac tttattttgt tcttccaatt gctccttggc aaagtcaagg
    16621 actttttctt gtctaggttg ttctagttgg ttgtagatgg acactatttc agatgtattt
    16681 tttggggcat ctagcagaga cgaaaacacc tcgggtctga tacctaaagc tgagcaaatt
    16741 tttatggcat tctcgacgtt agcattcatt attcctcgct ctaatatcga gcgaaccgtt
    16801 gagtaaggca tgttgttttc ttctgcaaaa gattttacag agctataacg agaaagtata
    16861 agatgtttta gattttcttc attcatggct gcctctcttt ctgatttcat tataacacac
    16921 gatttttcgt ttgtctaaca aaaaaacact aagaaatacg aattttagta ttgacaaaca
    16981 cgaaaaaaag tattaaactt gtatcaagct cagatgagct taactttaaa accaaaaaca
    17041 cgaaaaatcg tgttagaaag gagttatatg ttaaatattg ataaagtgcg aaaagaaaaa
    17101 ggcgtagcaa tagtagacat ggctgatttt cttggcgtaa gagctcaaac agtaagcgat
    17161 aaattgcgcg ggacttacga ttttaaattt actgaggctt tggcgttgca acaaaaattt
    17221 ttcccggagt acgatttaga atatcttttt aacaaagcag tagacactgc ttaactttaa
    17281 aaccaaaaac acgaaaaatc gtgttagaaa ggagaaaatc aatatggtga caaaattttc
    17341 agaagaaata aaaatagtaa ggacgaagtc ttctgtttat gtaaacagcg tcttagacgt
    17401 tgcagataaa aaagaccccg cgtctgttgt agcagtcgca gagcttttaa aggcgtataa
    17461 gtcgttaaca gaattgtaat caactatggt gacttatata cgtgacttga tcgagattga
    17521 ccaaaacgat gtattgagcg tctgatagtt tcagttcaat aatatttgga ttatcagggc
    17581 actcatttgc aacttggcag aatgtgtgtt gcttaccatt tgtgaacatg attgtaatgg
    17641 tatcagtttc attcgctagt tgttcgataa tatatcgttt catacaatca cctcctttct
    17701 gctcatatta tagcagttaa ggacaactag agaaaggaca ctatgcaagc aaatcgaatt
    17761 ttttacggaa aagaaaaacc aacaaacgca gtagcgggcg attgctggtt tagagataac
    17821 gaattaatga tactcaagga caattgggaa gctagcgtaa acaacttaaa gagccctaaa
    17881 gttatcggag agatagaaat agacctagag cagcatgatg tactgctgac agccagaggg
    17941 aaccgtcctc cactattaat gattgatggg ataatgttgg gcggagtatc taaggtaata
    18001 attataaatg agttatccga gtcttgcgca attgtctctc ttaatgagta tatcaaggag
    18061 aatttgttcc cttttgacga ttttgaatca cttcaaaggt tatttcaaaa gggccatcag
    18121 aaattatccg tacgggaact ttgcttagaa aaacgtttag gtgagcattc ttatcaagac
    18181 catcgaaaaa gctgcgatga atagtaaaag ttttcttacc gctcgcaaga gctttctcgt
    18241 aatcctgagt cagtagttta acagagagat ctaattgata gtcgtacact tttgtttatc
    18301 ctccttccac taggataact acattataca acagaaagga acaacatgaa tcaactaata
    18361 aacatcaccc taaacgaaaa tcaagaacca gttgtcagtg gtcgtgattt acataaagta
    18421 cttgaaatca aaacagctta taaagattgg tttccaagaa tggctgaata tggttttgaa
    18481 gaaggtcagg actttagctc atttttgagc aaaagtacag gaggtcgtcc tagtcaagac
    18541 cacgttctaa aactagacat ggcaaaagag attgctatgt tacagcgtaa cgagaaatct
    18601 aaagaagtcc gtaaatactt catccaggtc gagaaagact tcaacagccc agagaaaatc
    18661 atggcaaggg cgttgctgat ggcggacaag aaagtgcata aattagaagc tcagattgag
    18721 gctgaccgac ccaaagtact atttgctgat gccgtaagtg ctagcaaatc atcttgtctg
    18781 attggtgagt tagctaaaat cctgaaacag aatggaatca atattggtca gaataagcta
    18841 tttcagtggc ttagaacgaa cggttatcta attagcagac gcggcgagtc atggaatcag
    18901 ccaacgcaaa aaagtatgca gcttggattg tttgaactca aaaaaacagc catcaatcac
    18961 tctgacggtc acactacaac aaatgtaacc ccaaaagtta ctggtaaagg ccagcagtat
    19021 tttattaata aattccttaa tcaggaatat ctgccagttt agaaaggaaa caaaaccaac
    19081 gaaaaggaga aaagtatgcc agaggattta atcaaacaac tagaagctgg ttcagaattt
    19141 ctagcaaaga catgtttaca tagcaagatt attatcacgg tggatggtgt tcggcttgtg
    19201 gaaacaaaag agttccaccc agtgagcgga actctactag attagacaat acgtgtataa
    19261 gtgtgtatct tagctaatct atgaatattt gagccaacag acccaacaag aacagaacgg
    19321 tattccgttt ggcttacatt gtgataatgg taaatagaac cattattaaa ctcaacttcc
    19381 aaagtgttat tttcccaacc aacacttcgg acgttactag atgaaacgta ttgacgttgc
    19441 ataacttttt ctcctttccg cgatgatagc tttattatag cacgcaagga gaatacaaaa
    19501 aaagtccgac gggaatcgga ctcgacaata atatttatga ggtaatttta tcatggatag
    19561 tagattatta caaatgcttg atgagtttga ggcgggtctg atagaccgta aaatcaaagt
    19621 cataggcatg cttaataacg aaacggaaat ttatccgcta gagcttaaca aaaagcaaat
    19681 cagtaagatg ctgggagttg atcctaaaac atttgacgta agatttaata gccacaaaga
    19741 ttttccgcgc atcgaaacgg gaggtcggga aaaataccca cgagatttag ttattgagtg
    19801 gtatagcaaa aactgggaaa ggacggggat aagatgatta aaaaactatt taactttatt
    19861 tttgcaaagc caaaagaaga atcaaggcaa ccttatcaac aaccgagagg ttttctggat
    19921 tttgaaacag gtaaacgaat tgaaatagat ccgataacaa gaaaggaata cttcgtatga
    19981 tgcatcaaat taatatatcg cttagaaatt ttgtcgagac tggagagatt gacaacatct
    20041 tcgacatttt tagaatttta gatttctact ttcgggaggt ggtcagctga tgcagtacat
    20101 ttttcaagac gttgagaggg agttacacga gcgttagtaa tgagtttgtc aacgataaaa
    20161 aactttataa caaggaaaag ggattgttgt tgaccattct tagcaatagc gatgagtggc
    20221 gagtatatcc ggaggaattg gctaaacgtt gcagagatag tgttgacgct gtcagaactc
    20281 agctaaaagc acttgagaaa gctggataca tcagaagtta tcggaagtcg cttggcgggc
    20341 gatatggtac cgaaacccat agattttgct cagacacaaa aataagtgat gaggtttttc
    20401 aagagctgct taaagaatta aattgctaat gtgcaaattg ctaatgtgca aattgctaat
    20461 gtgcaaattg ctaatgtgca aattgctaat gtgcaaattg cctaactaat aaatactaac
    20521 actaaataaa tactaaataa taataaatac taacaaacaa taagcatcat catcaacagc
    20581 aggaggagct atggacgaaa aaaagctttt tgaaaatttt caactaactt tcggaagaat
    20641 gatatcgcca tttgaaatag aagatattca aaagtggatt caccaggata atatgccgat
    20701 tgatgttgtt aaccttgctt taagagaagc ggtagaaaac aacaagatca attggaagta
    20761 tatcaacaaa attttggtgg agtggcataa agctggagat acgacgattg agaaggtcaa
    20821 agagaggttg cagagatttg aggatagcaa agaacaacga catgcaacta tctcaaatgt
    20881 tcctagctgg tcaaatccag actaccaagg cccgacatac gatgatttaa aagtaaatcc
    20941 aagcgaggtg tcagatggcg caggagattt ttgatggatt taatgcctta atcaataaaa
    21001 tgtatggcag acaatctagc atagagacct ttaaccgatt tgtcgagtat tgtcaaaaaa
    21061 ggagagagga aaacggggtt gagcctgtat taaatccgat caatcttttt gcattcggcg
    21121 ttggaatcac aacggaagaa gctaataaat taagaataaa acgctacaaa caggagaatg
    21181 gattatgaca aaacaatatc gagagacact tatctggcat cgggcaagtc acaaagagcg
    21241 tgagaagctg cttgatttcg ggctagttga taaatcacag tacatgacac tattacgcca
    21301 attgcgcaag aaatatgcga tttaggagga aatatgacac cagaacaagt ggaaaaagca
    21361 aaaatcagag ctaaacgaga acttgaaacg tttagcatct accttgacca ggcgattgtc
    21421 gaatacggaa gtacgctaag tccacaagaa gtctttttag cggcagggtt tgcctacctt
    21481 ggtgcaggtc agactgacat acatgcggcc atcgaggggt tatatgagca aatccaatga
    21541 ttttaatttt agcgatgact gggaaagcaa ctatttcgag gtccaagctt tgctagggca
    21601 agagatagac aagctccaaa acagggtcat agcgctaagc caggaaaaca atagattaaa
    21661 agcgaggaaa tgaaatggca agtgaaattg taacaattca aaaagatatc actgatatcg
    21721 ttaattcaaa aattagtatg cttcagaacg aaggtcttgt aatagcgcca aactatgctc
    21781 cagcaaatgc tttgaagtca gcattcttta aaattttaaa aaccaaagac agaaataaga
    21841 ggcctgctct tgaagcctgc acaaaggact caattgcgaa ctcgctcctt gaaatggtca
    21901 cccaaggatt atcacctgca aaaaatcaat gctattttat cgtttacggg aatgagctcc
    21961 aactgcaaag atcatatttc ggaacaatgg cagttttatt gcagcagaaa aaaattaaat
    22021 caattaagtc agaagttatt tatgaaggtg acgattttga gcttgaaatt gtagatggtg
    22081 aaaagaaatt caaaaagcat gatactcatt ggaaaaatca agacaatcca attgaagggg
    22141 cttattgcat tattgaggat atagatggta acactaagct aacactgatg acaaaaaaag
    22201 agattgataa agcgtggtct aagacaaaga ctggtggagg gacacaaaaa gaattccctc
    22261 aggaaatggc caaaaaaaca gttatcaaca gagctgctaa gttttttatc aatatcagtg
    22321 atgacagtga cattttggca gattctatta acaagaccac cgcagatgaa tatattgacg
    22381 atcgtcaagt aaaagatgta acggaaacac agtcacctgc acagacacta ctcgataaca
    22441 tgaagcatga cgaggaaatg agcaaaatcg aaacgatgca aaatgaacaa ttgatgcatg
    22501 atccagaaac aggagaaatc attgatgcag aggttgttga ggcggaccta aaggaatctg
    22561 atatggagga gccattctaa tgagcgaaaa tttaacactt tttgaaaatt taaatgacat
    22621 taaaccagcc gaacccgctg agctgagttt tgattttgag tttactccag ccgaaatcaa
    22681 aatcaaaggg aaagagaagc tcgaagagat tttagcagcc tacgctaaaa aatacgatgg
    22741 ctacacagtg acagccgaaa cctttgaaga cgatgcaaag gttagagcaa aactcaatac
    22801 tttgcagaaa gatattaata actctgtaaa aacaaaactc gcagaataca ataaccctct
    22861 tgatgatgtt aagcagtggg ttaactcaat tattgagcca attaaaaaaa ttacaaaaac
    22921 gattgatgag ggtgttaaac actttgaaga aatcgaacgt cagaagcgtg caaatacaat
    22981 caaagaaacc tttgaggctg ctattgctga aacaggtgct gatattgata tccgcttgtt
    23041 cgaatctaac tttgacgata tgtcggctaa aggatatttt atggctgaca acgtccgcgt
    23101 caataccgct accaaaaagg ccattaacaa attggttgct gaagaagtag caaaaaaaca
    23161 ggaacatgag caggcgctta tccaaatttc agaagctgct gccaaagcgg attttggacc
    23221 agctatctat atcaaacgat ttgaaaatgg cgcacaactg gcagatatct tacaagcaat
    23281 cgctgacgat aaactgcttg ctgacaaggt gcgcgaagaa gaaaaacgca aagcagaact
    23341 atctaagcga gtagaagaaa tgacagccct ggcacaacgt gaagggttgc aaccaggcaa
    23401 atatgtaaaa ttgcttgaag atggcaagtc tgctttagtc gtttttgaaa ctctgatgga
    23461 cgattctaaa aaaatgcagg ccaagatagc acaaaaaaac gcagaagcgc atcagcaaca
    23521 aatagaacag accgaatata tgtctgaggc ctcaaattcg ggggtaaacg agcttgaaac
    23581 agacaaggtg ataaataata tcatcaaaca agaaaatgcc ttagaagcca aaatagaacc
    23641 gaataagagc gtcacaaaat ggcaaggtga ttttaaaata actttcccgg attcagaaac
    23701 agctaaacta tttggcgggc aaggcggatt atacgaaaag catggcgtga ttgttgaaaa
    23761 attaggtgaa tgggtgaaga ttaatgacta aattaaccga agaaaattat tatcaagacc
    23821 gagaatggtt gtctaactca agatttaagg ctttccttga ttgtgaggct aaagctttag
    23881 ctgtcgaaaa caacgagtgg gaagatacca gagatgagac accgcttttg gttggtaact
    23941 accttcacag ctatttcgaa agtcctgaag ctcatgagaa attcaaagcc gagaatggag
    24001 ctaagatgat ttccagtcgt ggagttacaa aaggggaact caaaaaagag tacaaagtag
    24061 cgcaaaacat gattgaaacg ctagaaactg atgagatatt taatctcatg taccatggcc
    24121 aatctggtga taatgttttg aaagaaatga tcatatacgg ggaaatctta ggcataaaag
    24181 ttaaaggaaa agttgattca atcaatttaa caaaaggtta tttttgtgac ttaaaaacga
    24241 tgaaaagcat acacagcgac gaatggagta atgacttgcg taagcgtgta cctggtgtag
    24301 cagctaacat tatcgggttt aaataccata tccagatggg gctctatcaa gaattactca
    24361 gacagatgac tggaaaaacg cttcaaccgc taatcattgc aatcagtaaa gagaatgtac
    24421 cagataagga actcatcgaa cttggccaaa cgtggctaga tgaagggttg caactttttg
    24481 aaaacaatgt ggagcatgtg cacgaagtca tcattggtaa agctgaagct aagtcgtgtg
    24541 gacgttgtga ttattgtcga agtcagaaaa agcttaatag ggtggttgat ctcgatgatt
    24601 tgattgcagg aattttttag gagatcttat tgtattgcaa agtgatgctc ggcctttgca
    24661 gcaacaaata ttttccgagc gagaaaggaa aattgcaata tcgtcaagtt aacaggattg
    24721 atgatataaa gagttgctac actcgtcctt gctaatgctc acacacaatt ttagggcgag
    24781 tgtggatttt aaaaaggtga aaatatggaa caaatcaaaa ttacaggaac tgacacaata
    24841 ttaattttag atagagtaga tagggccttt gtcattgagg gtaatctagc tgaaagatgg
    24901 cgttttacta gcaagtttat aaagattgac gatgagctat cgctggacga ggacggcgaa
    24961 ttgtttgaga tagtttatga cttaatgcta gaagcaaaac ctcacaacgt gattaatcta
    25021 acatcatcat attttgctaa agaacataag aaagacacag atgaaatcat aaaagtattt
    25081 gcttttatcg aagataacaa gaagaatatt tttgaaaccc ttggcattcg cggggtgctt
    25141 gaatgagcaa tctagtatta tcgctagaca tctcaacatc tggtacaggt tgggccttat
    25201 ttaaaggctc agaccttatc cagagcggtg tcttaaaaca taagagcgac tcttattttg
    25261 aacgtggacg ctatatggct agcaaattaa ggttgatcca gtcacgagca ttaaaaaaat
    25321 acgattgctc ctttagcaca atcgcagtcg aaaaaaactc ggttatgggt ccaaatcaac
    25381 aatccatgct taaaatcggc attgtaactg gtatcatctt aggacgattg atagctgata
    25441 atgtcgtatt tatcaatgtc tcaacttggc gaaagcactg gaagtttagc tacaaagacc
    25501 gctcaaaaaa agcaatgaaa gcacagtcaa aggctaaggc tgctgaaaac tttggcaaaa
    25561 tagtcaaaga tgatgaggca gatgccgtct tgattggtgc atactatgtc aatcaaggct
    25621 atcttgatgg attggagaca catgactact actaaaaaac acgttgtgag gatttacaac
    25681 aaaggtatta cagcaaccca cgcagttact gataaaaatt tatttacaga gtatacattt
    25741 gcgacgcagc aagatgccga gaattatatc agagacttag agctaaacgg atctaagtgt
    25801 gccctttgag tattatgaga ggagatttgc aaaatgatag acaccgatac acttgcagca
    25861 gtacgggagg ctgatcatga ctaaaaacga ctttttaaca ggttttgtac ttatactttt
    25921 agctgcttgc atttttgcag caggatttgt gattggatct gactgtagta gcgagcacta
    25981 cgagcaacaa atgacaggct tgcgtatgca gcttgttaac acgcagcagc agcttaagcg
    26041 tgcgagtgag gatagagcaa ggcggactaa aaggattgcg gatctgaccg ggaatggagg
    26101 atagggtatg atcgacgaaa tcgaactcga cctacaaaaa ccagaaatcc cacagtttgt
    26161 cgctgactac atagatgata tgcacaaaaa cgcacgtaca ttgagatacg cttttaaata
    26221 catggaaagt aacataaaaa tgcacaaatg gtgtgttttt gaaaggcaag aaacgtttgt
    26281 taatgctttt ttatacggct acacaataaa aaaagaaaag ctgtatattg ttgagatccc
    26341 taatcctaat agtggcatag aacacaaaca tattgcacta gcaaggttag cgaatggaaa
    26401 acttggattt tcagagatca tagatactga tttttattca agagaagatg tccgactcac
    26461 cgagtcagaa atccgcaaag attttgattg ggcatggaga gaggggtttg ctaaagaggt
    26521 gacggaatga gcagagataa aaccagaatc aggaacattg tgaagtccat gaaacagtta
    26581 ggtgctagcg aagaagagac agacgaatac atgtatctat gcgtgtttaa aaagcctcac
    26641 gtcatagctc aaatccgtaa aaaggctaag attttcagag gcgaagggtg gtaacagatg
    26701 gcatatttac gagaagaaag agaaacagtt attcattacg acgaattgga tgactgctgg
    26761 acttttgaaa ctaacgtccg taggcatatt acgaaaatag aaaaacgcat cgaactgtac
    26821 gagattctct cagaggaatt cgatgaccga ggaaggcgta tctatatctg tgcgaaaatg
    26881 aagacaggaa ctgtcagtcc ctttgcgaaa ccaccaagaa ggaaatagct atagaatcga
    26941 ttttaagctt caaaaacatg gcaagaacgc acttctggga acgtgaaaca cctagctaat
    27001 ataaatgtac cctagaacaa tttaaatcga aaaaatgatt agctacatag gttttaatcg
    27061 gcttatgtgg catagaccga aattaaacac agaaggatgt gatgacaatc tccttacacc
    27121 caaaaaatct aacgctggtt atcggtcacc agctattatc caaggcgcta atactgacat
    27181 cgtgtgcctg agctggctta taaaaaacga aagagagggc ttttctccac acaaaaagac
    27241 gtccatgcga acgcctcctt ggttatatct gttaacacca ttataccaca ctgagggggc
    27301 tttcatgacg ttttttcctg agattgatat ccaaaaaaca aaatccaatg ccaagcgtaa
    27361 attgaaagag tatccacgct ggcggcggat agctaacgat gtagatactc aaaaagttac
    27421 agctacttac tcatttgagc caaggcaacc tcatggagtc catagcaagc ctgtagagag
    27481 gttagcactt aatcgtgtgt cagcggagca ggagttagat gcgattgagc aagctgtcag
    27541 catgatacta gagccagaga ggcgcaggat tttgtacgat aaatacttat caccttataa
    27601 aaaagcggac aaggttattt atacagaatt gtgtatgtca gagagctttt attatgatac
    27661 gctcgatatc gctttattag cttttgcaga gctatataga gaggggtctc tgattgtcga
    27721 gcaaggagtt tttagctagt ttttatacag taatataata gtttttgtac aaaatagcgt
    27781 gttaatatag tatcatagca aaataacaaa aagagataac cattttacca attgactatt
    27841 tatttagtcg ccaactttaa ctacgatcaa acttgttatt ttgaaggtac atgggacgtg
    27901 caggttcgaa tcctgccgtc tcaataccag ctatttccaa aatggaaaca gttggaaaag
    27961 acaaaccccc cattccttta aaggcagata cgttctgata tggggctttt tatgattaac
    28021 tgcaagtaaa acaagggtcg caaccttgct tgtggttagt agacctagtg gtcgtttatg
    28081 cacgttcgat tcgtgcaagg tctgttgggt tgattgcaat aatccttttg tggacgcaca
    28141 acaaaaatgt gatgtaagtc acggctaagg tttgggcggc gatagaatag atgcgcaact
    28201 atcgttgggt cacgtctcag agtttgcata gttaatatta accgatgggc acaccctgcg
    28261 tcagtgggtt gtttatggat agcttagcaa aggggttaat gcgaccaact gtttagtttg
    28321 gtaggcgtga gttcgaatct cacactattc tttcaggaac atgaaccgtg attggaaaac
    28381 ggtagaggta gcgccttgat aattggattg tcgacggtct gattatatgt gtcggttcaa
    28441 ttccgactgt tcctgttcta gtcaccaatt gtggtggctt tttattatgt cacgaggagg
    28501 tgatggaaaa ttgctaagtt aactataaaa caacaaaaat ttattgatga gtacatcatc
    28561 tgtggaaatg cgacagaagc cgctcttaag gcgggttata gcaaaaaaac ggctgggcaa
    28621 atcggtgagc agaacttgaa aaaacttgaa ataaaatctg ccatcaacga acggctaaaa
    28681 caactcgaaa gcagtaaaat agctagtgca atcgagatcc tacaagttct tactgccgtt
    28741 cttcggcagg atttgacgga ggaggttgtt acccttaatc ctgtaacagg tgagtacgtt
    28801 actatgcaga aaaaacctag catcgcagaa gtcataaaag ctgctggtga gttattgaaa
    28861 cgttatccta tccaagaaca aattgaaaaa atcaagcaag aaaacgagtt gttacgcctt
    28921 aaaattgaaa ccgtcaaagg cgccaagcct gatacccatt tgatggaaaa actgctggag
    28981 gtaatcgaag atggcggtta ggataaaaaa gttatccaca aaacaaaaag acatcattag
    29041 acgccctttt aactacgaat tagaggtcaa tgagggaaca cccagaagtg gaaagaccac
    29101 cgctgggcat tttcgttatg ctaggtatct gattgagtca gaagatgaaa atcatcttgt
    29161 gactgcttat aatcaagaac aagcttatcg tttgtttatt gatggagacg gtacagggct
    29221 gatgcacatc tttgacggga actgcgaaat caaacatgat gagcgaggag atcacctgct
    29281 tgtaacaaca ccaaaaggta ataaaagggt ttattacaag ggtggaggta aagttaactc
    29341 agtcggtgct attacaggta tgtctctagg ctcagtggtc ttttgtgaga ttaatctact
    29401 gcatatggat tttatccagg agtgttttag gcgtacctgg gcggctaaac tgcgttatca
    29461 cttagcagac cttaaccctc ctgcgccaca gcaccctgtt attaaagacg tttttgacgt
    29521 ccaaaatacc agatggacgc attggaccat ggacgataat ccaatattaa ctgcggagcg
    29581 caagcaaaac attatcaata gcctcaaaaa aaatccttat ctttataaac gagatgtact
    29641 cgggcagcgg gtgatgcctc aaggtgttat ttatggtctt tttgacatgg aaaaaaatgt
    29701 tctagacact ttgattggcg agccagtgga gatgtatttc tgtgcagatg gtgggcaatc
    29761 tgatgccaca tctatgtctt gcaacatcgt aacaagagtt agagataatg gcaagataag
    29821 ttttaggctt aatcggacag cgcactacta tcatagtgga gcagatactg gtcaggtcaa
    29881 agccatgtca acatacgcca gagaacttaa ggctttcatt gactggtgtg ttaaaaaata
    29941 ccaacttcgg tactctgatg tctttattga ccctgcgtgt aaggctttgc gcgaggaatt
    30001 acatgccatt ggtattctga cgactggagc gccgaacaac gctcacgacg taaacagtaa
    30061 ggcgaaaggt atcgaagttg ggatagaacg tggccagact ttgatttcag acggtgattt
    30121 ttatctagta aatcacaaag aggaaaaata tgatcattat catttcctga aggaattagg
    30181 gctttatagc cgcgatgata aaggcaaacc aatagacgca aacaaccact caatggacga
    30241 atttaggtac tcggtcaatg tttttgtggg acgatacaaa atgaaatagg aggtagtcat
    30301 gtttagaaac ctctggacta aaataaaagg ggtgatgcaa aaaatgggat tgataaaagg
    30361 tttgaaagat ttgaacctgc accgcgaaat tgaactgtct gataagcatt atgatagtat
    30421 ccaaatttgg aaagagttgt atcaaggcta tcacgataaa atacacgatt actatgagaa
    30481 atctatctta gatggtcgta aaaagaagaa gcgtttgact ttgaatatgc ctaaagttgt
    30541 gacctcagag cttgctacat tgatttttaa tgaaaaatgt gaaattaaca ttggttctga
    30601 aaatgagagt ttgacaaagc tcatcactga aacgttagag aaaaataatt ttactcagga
    30661 gtttcaacgc ttcttagaat atagtttcgc cttgggaggt atggcaatca aagcatatct
    30721 caaaaaggac ggtactatcg gtcttaattt tgtacaagcg gatagtttta ttcccatttc
    30781 gtgggataat gctgggatta gcgaagccgt atttgttgat acgcagcatc gtggaaaata
    30841 caagtacacg catttggagt ggcatacttg ggaaagtgag ttgtatgtag ttgctcacga
    30901 gttatttaga actgacaagt caaatgatga tgttggcatt cgcgtaccga taacagagat
    30961 ttatccagat ttaaaatcac aagtagtcat cgaaaaacta tcaagaccgc tatttgttta
    31021 cctcaaacct aattcggcaa acaacattga tctatcaagt ccgctaggga tttcaatcta
    31081 tcacaattcg tttgatacct tgcgagcgat tgatattgcc tacgatagct ttgagcgtga
    31141 gtttcgactt ggccgtaaga ggatattggt tccagcgact gccattcgta ctgtagtgga
    31201 tagcgagggg aatttccacc gctattttga cgcaacagac gaaacatatg aggctttcca
    31261 cacaggtgaa gacagcaaaa ttcaagatat caaagatatt agtgttgaat tgcgagttga
    31321 tgaacatatt gcagctatta acgcactgtt gaacttactt agtatgcaga ttggctttag
    31381 cccaggttct ttcagtttcg atggagtatc gggtgtcaag acagccaccg aggttatctc
    31441 tgagaattct aagacattcc gcacgaagca atctcatgaa acgatggtag aagcaacatt
    31501 gaaaaatctt gttgcgatta tcgttgattt tggggatctt tatggtttga tcgagggtga
    31561 gagtaagtat aatgtaactg taacgtttga cgactctatt gcgcaggaca gaacccagga
    31621 cgctcagtat tatatagggt tggtcgcagc tgggttaatc agcaagaaaa aagctatgat
    31681 gaagctgttt aatctgtcag aagaagatgc agagttggaa atccaaacta tccacgagga
    31741 aagccggaca acaaacgata tgtcaattga tttatttggt ttggacggtg atgcttagtg
    31801 gattatgata ctcatatcca gctgtctttt gacttaatag agctttattc tgatgtcgaa
    31861 cgtgaattgt tgacgtcaat aggtcgcagg tttgcaaaac actatgacga aatggtagct
    31921 ggcgacatca tggattggca aattaggcaa ttactcgaag ttggagagct gagaaaagag
    31981 cacatcgaaa tcatgcgaaa aagtgcacgc gtgagtcgtg agcgtatgat tgagatgctg
    32041 acggaggcag gttatacctc cgcaggaagg tatgaggatt tttttaaaga ggcatacgtt
    32101 aaaggtttaa tcaagctcaa tccatctgct gcagacaaca gcatgaggtt gttgcgagtg
    32161 ttaaatactt acatcaatca agctgaggac acacttaatc ttgtcaatac gaccatgtta
    32221 cagtctggcc aagatacttt tttagataca gtcaatcaag ttgttgctta tgtttctaca
    32281 ggtatcaaga ccccacaagt tgctatgcgt gacgctctaa aaaatgctgg tcaaaagggc
    32341 cttacagtct ttcgtgctaa aaatggcgcc cagtggtcaa cggagactta tctcaatatg
    32401 atcactcgga cgatgaactc taacatttct aacgctatgg aagatgagcg taggcatgag
    32461 tatggtgttg attacatcga ggtatctagc catgctggcg cacgtccaag gtgtgctcct
    32521 tatcaaggtc ggatatatta cgatggtgtc ggagatgatc cgctagagaa atacccgcac
    32581 ttctcagaga cttcttatgg cgaagctgct ggattgtttg gcgttaattg cggtcatcat
    32641 aaatatcctt acgtcccagg tatgagtaaa cagacctttt tcccttacag taaaagcgaa
    32701 aacgataaaa cctatgcaga gtcgcaggta caacgtaaat tagaacggga agttaagcag
    32761 ctgaaacggg aacgagcaat tctaactgct gcgaaggaca aagagggggc taaattagct
    32821 tctcaacgct tggagaacaa gtggcaggaa ttgcgtcagt ttactgctca aacaggcaga
    32881 acgagacgat acgaccgcga gaaatcgcta aatactattt tgtctgagga caagaaaaaa
    32941 gccattgtca aagataattt gaaaatcaga gatgagtatc gagcgattaa gaaagctatc
    33001 cctgaagtag ctcctaaaaa tcttgaaacc tattatgata tgcgttataa tggtggcaag
    33061 atatacgagg atttagttag ggattacaaa gactatataa gatggtctaa agctgaattt
    33121 cctactaaaa aatcttttga agggcatatt gatagtcact taaaagagtt tccaggattg
    33181 actggtaaac aatatcagaa aaaggctgct gacttattat ctagaccgat aactgataat
    33241 attttaggtt atgatacaga ttctagacgt gttaggtatg acttagaaaa taacattttt
    33301 gctttagggc gcgttaaaca aggtacgatt acgactatgc tgaaaccaaa ggaaggggtt
    33361 gattactttg acaatgactg gaaaagagag tttgataatc ttaaatgatt tagaatatgt
    33421 ccattgtcct gtttgtggaa ctttgaccga ggtttatgat atttgcgata cttgtaaatg
    33481 gcagaatacc ggtgagacaa atattgatgg cggtcctaat tatattacac ttgaggaagc
    33541 acgacgaagg tgggcaaatg gtgaaccttt gcgcaacttt tttaaagacc aataatacaa
    33601 gcactgtaac agtgcttttt ttgtactcaa aaaaggagag agtaaaatga acaaacgaat
    33661 tgaaaagaag cgtcgcacac aaatgatgtt agacagaatc ttgcgcattg tagaattgat
    33721 gtcgcaagca actgacgaca actttgctat cttggaaaag cgcttagaaa aagctgaaaa
    33781 acgtaacgaa gagcttatgg aaatcatctt agtaaacgtt aaagaggtaa ataaccgctt
    33841 tgacgagcta gaaatctgcc agaagattgt tgaagatgat gtcgcagagc tcaaaaaagc
    33901 taagaaaaaa ggctggttca gccggaaata acttaatcgt gtcgaattcg atgcggtttt
    33961 attttgccct gccgcatggc gataaactag gtaaaaataa aagaaagagg tctaaaatgg
    34021 ctgttattat cgtacaaaca cgaggcggag atattgaagt tcccacccca ttaccagcaa
    34081 tgcaagctaa taaagcgatt caaagtcaat tattcgataa ggagctgact tttttatgcg
    34141 tggataatca tgcttttgct aaaactgagg ttttacacgt tttggtcgaa acagaagaag
    34201 atgaagaatt accacagtca aaacataagg aggaagaaac atgctacatg gattaaaaca
    34261 ccgtttgttt aaactagccc cagatactgg agcaggcgga ggcgctgaag ttactagcga
    34321 gactaacgct gaagctggac gagttgagca aacagtatcg caacaacaag ctgatccggt
    34381 tgatactgag gcaatcaaaa atcaagcaat taatgaggtt ctaagtcaac taggtgtttc
    34441 ttcggtagaa gatgccaaag caaatctagc ttcttggaat gaatatcaag aaggtcagaa
    34501 aacagagttt caaaaaattc aagatagttt gactgtggct aataactctt tggctgagcg
    34561 cgacactatg attgctagct tacaagctca gttagctgct gctcaaatgg gagtgcctgc
    34621 ggaaaacacc tccgatgtta tcactttggc caatagtttg gtccacgata aaacagacat
    34681 caatgcagcg attactaccg tacttgagaa atatcctcat ttcaaaggag gtgatgccga
    34741 tgtagctgat aaacctaact ttgtgactca aactcagagt caaacggaaa cgacggaaga
    34801 cgcttttttt aaagcgttag gactaacaat taaggaggac taatatgtca atcaattata
    34861 ttactaaaca tgaaggaata ttcgaaaaga aactaatgca aggcgctttg acgtctaact
    34921 tagagacacc aaaagtcaac tggttaggtg caaagtcttt tgagctacca accatctcgg
    34981 tgactggcta taaggcgcac acacgctcaa aagggtataa cgcaggtact gtatctaacg
    35041 ataaaaatac ttatacgctc ggctttgatc gtgacgtaga gttttttgtg gataaggcag
    35101 acgtcgatga gactaaccaa gagctgtcta tggctaacat ctcaaacact tttatcacag
    35161 agcatgcaac gccagaagtt gacgcttatc gcttttcgaa gattgccaca aatgcgatcg
    35221 ataatagcca ttttaagcag gaagatgact actctactac taatgtttat gagcgcttaa
    35281 aagctgctat tttgcctatt cgcaagtacg gagctggcaa tatcattatc tatgtctcca
    35341 gtgagattat ggactttttg gagcgctcaa aggactttac acgctcaatc gcgacaacat
    35401 caccgcaagg gattgatact cgtgtgacat ctcttgacgg agtgcagctc atagaggttt
    35461 gggacgatgc ccgctttaag actaaatttg attttacgac aggctttgtc aaagatggca
    35521 gcggtaaaga cattaacttt ttgattgtgg ccaagcctgc ggttattgca aaagctaaat
    35581 ttaactctat ttatcttttt gcaccaggtc agcacaccga aggggacggg tatctatatc
    35641 aaaatcgctt gtatcacgac ctttttgtgc ttaaatctaa acaagatggg gtttatgtat
    35701 cccataaatc agcttaggag gttaacgatg aaaacatacg agaaggacaa tcaagtctat
    35761 aaagtacaag aaggcagcga gctggaaatt cagctgattg ccgacggctt taaagaaatt
    35821 attgaagcaa acgaaaagga aactgatatc actaaaatga agcttgataa gctaaaggct
    35881 tatgctgaaa atgaaggcat tataattcct gaagatatta agaaaaaaga agatgtttta
    35941 gcttttatta aggaacagca gcagagaggt gagtagtgat gctcaccttt gatttttaca
    36001 ataagggata ttgtggctca cagctgaatg aagaaaagtt cggggagctg tcaaaacgtg
    36061 ctgagcgtaa aattttggca cttattggct tgaaaaagga gcaagtgaag aatttgccac
    36121 ttgatatttt agaggcggta aaaatggctg tctgcgccca aattgagtat cttaacgcaa
    36181 taggcgttga aagtgctatc ggagtaacct ctgtaaccca agctaaagtc ggcaatttta
    36241 gttacacaga cggaaagaaa gcgactgtat cagctagtgt tggctctgtt ggtgttagcc
    36301 ctgacgtgct agactatctg cttccgagtg gattgttata caagggggtg aatacgagat
    36361 ggtaaaagaa gtcaaaccta tccctaaaga gttattagtt gacacagtta cttatctagc
    36421 agttggcaac aaagacagct ggggagcaga aacggtagta tctacagaat tgtcacaggt
    36481 gttagtacaa cctagaagca gtatccaacg tgggcaacaa aacgagagta atagctacga
    36541 gttgttactc ttttttgatt gtgtaaactc gttaccagta gatcatcagt ttaaggttga
    36601 cgacaaaatt agttatctag gaaaagagta tcgtatcgca agtgttgagg tactaaaagc
    36661 ttttgaccag tcgccacatc actatgaggt gatgctagaa tgataggttt taaggttgaa
    36721 gtcatcttta acgctagtaa attgattgcc aagagtgaag catctgcaaa gacagctcgc
    36781 tttgctttaa gtggtcaaat caaaaaggat agtgacaagt atattcctgc tcgtgagtgg
    36841 aatctgcgag atagcggaag agtaactgaa cgctcagtat cttggcatac accgtacgct
    36901 agacgactct actacaatcc tcagtataac tttagcaagg ataagaatcc gaatgcacaa
    36961 ggcaagtggt ttgaggttgc taaagcaaat catgcagagc attggtatga gctaacaaag
    37021 aaagcctatg gtgctgagtt tagaggagat taatcatgac atttattgat tttttgctca
    37081 gaaaagttca agaagtgagc ggagcggaac cggtccttgg cattatgggg aatagtgata
    37141 aggttgctat tatccctatg gctggaaatt ttgacaatcg agctcttgac gaaagtaaga
    37201 ttaggatttt tactttccaa gttttggcca agagtaaaaa acagcaggaa gcttttttga
    37261 caacagaaaa cttggtcaat ggtctagacg gtctatcaaa tgagccgttt actggaggat
    37321 atctcattaa gctggagtgt acgacgacca ctaactttgt tgaaaaagat agtgacaaaa
    37381 attatttata tacagctctt ttcagagcag aattaggagg ataagaaatg gcagcagata
    37441 agccaacttt ttatttacaa tccgagcata agctcgaaat ttcagaagat ggaaaaactt
    37501 ggatgcgact agcaggtggt atcagtgaat tagaaccaga cggaaatgaa gaagtatcac
    37561 aagatgctta tcttgacggc tctgaatctg atgttacagg aggtcagcta gtactagcct
    37621 taactggaca tcgtctagta ggagataaag ctcaagactg gatctatgca cgtcaattcc
    37681 gatatggggg caaacgtcgt ggttttacgc gttggacatt gccaggagga aaaacacagt
    37741 ttacctttgc ctctacgttt gcaaatatca aaggtccatc aggagcggct aacggtaaag
    37801 gtgaaattga atttgaaatc cattcgaacg aaacacttgt acctaataaa gtagttgtag
    37861 aagtcactaa gacaaacaaa gaacttgcgt ctgaagcact tggtttagaa cgtcaagagc
    37921 gataagtaga aaggatagtc agcaatggtg agacagtttg aatttaagaa aacggttgaa
    37981 gaaattgaga ttgcagggga aatctactta ctgcctcttg atgatgataa cctcttacgt
    38041 atccaacgtg actttattag ttacggaaaa gagatcgaag aactccaaaa agttgaggta
    38101 gaaaaaggag atccagacga tctggcggat aatcataagc aacagctttt agtaatgaaa
    38161 aaggtcatcg agtcaccatt tggagaaggg agttttgaga aactttacga agcatcaggg
    38221 cactctttaa tgaatatggt tgacttattg gattatcttg ttgagttagt cgctgaaaaa
    38281 gttgagcaaa ataaggctcg tgccactaaa gcaaaagaga agtattactc ctcgaagcgc
    38341 aagaaaaagt aggtagctta tgaagttgac agaaacatat gaagttcttg ctgatgcttt
    38401 tgaatttggc ggtcatatcg taactgttga cttggctttt gatgtcgtgt tgcgagtcat
    38461 ggagcttctt gccgacgcag aagtcaatga ctacgctaaa attgtctgga ctttggatat
    38521 gctcttgcca tattttgatc gtacggagtt aagttttgat gaagaatttg aaattttcga
    38581 atatatccta aagacgttta tctatgaaca agaagacgga gaagatgaca gtttaggagg
    38641 aatgtcacaa acgaaaacaa tgcattttga aaaggatgca gagttaatct ttgcgtcctt
    38701 ttttcaaagt tatcatcttg acctatttga acaacaggga aaattgcact ggcgaaaatt
    38761 tatgtcactg ctcatgaatc tgcataaaga cactcctttt aaggaagttg tcagctatcg
    38821 tgtcatgaaa gtgcctaata aagatgaagc atcggaagag tatatcaaac acgtcaagaa
    38881 gatgaagcgt atctattcgc tagaagacga atctgagcat caagcgctaa atgatgacaa
    38941 gctttcagcg ttagcagcaa ggtttggagg tgagtagatg gcagatggta gtgttattat
    39001 tgataccctg ctaaagactg agaaatttaa ccaaggtgta gggaaactac aaggtaaatt
    39061 agctggatta ggatcaaagt tgaccagcat tggtaccggt ctaactctag gcttaactgc
    39121 tcctattgta ggaatcggag cggcatcgct cagcacgttt actacatttg aaagtcaaat
    39181 gaatcgtgtt aaggcgattt ctggagcaac agcaagtgag ttcagaaaac tagaagacca
    39241 ggctatcaaa cttggagctt cctctgtttt tagtgcgaca gaagtagcac aagctcaaga
    39301 aatgatggct tctgcaggtt ttaaagtcgt cgatatctta aaagcaatgc cgggtgttat
    39361 gtctctagct gctgtatctg gtggggatat ggcattagca agcgaggcag ccgcaacagc
    39421 tgtcaatatg tttggacttg aagctaaaga cgcagcccat gttgcagatg tttttgcaca
    39481 agctgctgcg gatactaacg cagaagttgg agatatggca gaagccctaa aatacgccgg
    39541 acctgttgct ggggctttag ggattagctt ggaagaaacc gcggcagcaa ttggtatcat
    39601 gtctaatgca ggcattaaag ggtcacaagc aggaacaact ttgaggacaa gcctttcacg
    39661 acttacggat ccaactaaaa agatgcgagg aatcatgtcc gaattaggac ttgaattttt
    39721 cgatgttaat ggaaaaatga agtccttatc tggtattacc aaagaacttc aaaccaaaat
    39781 gggtgattta actgatagtc aaaagagtgc agctatctct actttgtttg gtaaagaagc
    39841 aatgtctgga atgcttgccc tagttaattc tgctcctggc gcattagaca agcaaacaca
    39901 agcacttatc aattcaaatg gtgctgctaa agaaatggca gacaccatga atagtggtgt
    39961 caagggatcg attgaggagc ttaaaggttc gcttgagact gctggaatct ccataggtaa
    40021 aatattggcg ccagccctaa cgtcggttat cggggcgata acaagccttg tgaattggtt
    40081 caataaccta agtccgacaa tgcaaaacgt ggtagttgta ctcggaagtt tacttgctgc
    40141 cattggaccg gttgtcctta ttataggggt tgttactact cagatagcag ctttccagca
    40201 aggcgtcgga ctagtcttta atgctgtcaa aggattacaa gctgcttttg cctttttgac
    40261 gagtcctata gggttagtca tcgtagccat aggtgcacta attgccgtat ttgtttattt
    40321 gtggaataca aacgaacaat ttagaacgaa gatcattgag atttggacgg ctatttcgaa
    40381 ctttttacag cccatcatac aatttattgg taatttcata agggaaacgt ggactcaatt
    40441 agctactttt tggaacgaaa atcaagcaac tattatgaca atagcccaga caacttggtc
    40501 atttatccag acgatattta caacagcaat tgaaatgata aaattggccg ttagtgtttt
    40561 tttagggtta ttgcaatcaa cgtggtctgt aacttttaat tctcttaagg ttatcgcaca
    40621 ggtcgcatgg gcttttattt ccaatgtttt caagggaagt ttagggtcca tacttgcggt
    40681 tgcatctgct atatttgagc aaattaaatc aacgattgat cttgcgatga aaattattca
    40741 aaatatcatc aaaatcatac tatccgcgat agaaggtgat tgggacggtg tattagaagg
    40801 tatcaaagga attgtttccg catttggaga ttttattcaa tcaactttct caaatatgat
    40861 ggatactgct aaacgcttag tcggagctgg aatagatacc gtaaaaggaa ttttcgattc
    40921 tttgtggaat attgacttgt tcggagccgg tcaagcgatt attaatggat tcttaaatgg
    40981 tttgcggtct atgtggggag ctgtcacaga tttcgttggc ggtattgcaa gctggattgc
    41041 agcaaacaaa ggtcccatct catatgatag ggtactattg aagccgcatg gaaaagctat
    41101 tatggacgga ctcggtaata gcatgaaaac taactttaag gacattcaga aagatgtttc
    41161 tggcatggct gacgatttaa caagaagttt tcaaatcaaa aggttcaacg gttttttgcc
    41221 agaaaagtat actactaagc ttgatgagct taaaaaatat gcgcaagcca cgcttggcgg
    41281 aatgatttta gcccctaaca tggcagttca accgacagtc gttgttaaca tcagcaatga
    41341 agcagatagc gatatcatca ggcaaaaagt caatgctaag aatgcacaag atgctattat
    41401 taatcagtta ttcaagaaag ggtaaaacat gttcagtata gagtttttag acggagagcg
    41461 actaagcgcc gatgaacgag gatggaaagt taaagagatg tcctcatcag gacttgaaca
    41521 aaacgtcgtt agcgagtctc ctaaaatgcg ttctggtcgc cttgtttatg gtctttatca
    41581 tggcatcaaa acttatcaac ttgtttttac aaaaatcatt aaagataccc ttgattatag
    41641 ccgtttagta gatgaagtta attactattt tttacgtgat gaaccatact atctttaccg
    41701 cgactttaga aagaaagctg atcgggtgga cttgccgaag aagcgggcga aggtgtttac
    41761 taagtcaatc gaccatcaaa aaaatgggct taaagttgaa tttacagcta agctggaatc
    41821 ttatgaacta ccctacgaag aagatactga ggttcagcgg gtcacttgga cggcaacaca
    41881 ttcatggcac aataagggag ggcatcgcct tgaccctcgt tattgcccaa tgaagatgac
    41941 cataacagta tcaggttcag gagctgaact taaggtgcta tttaacggtc agccttattt
    42001 ttggtataaa aaatcagtta aacaagggga tatctttatc attgatggga cggacgttga
    42061 aaaaaataga tacaattgtt ttgaagattg ccataagcaa acctcttttt taaaaacagg
    42121 aaataacaga atagatattc aaggagcttc gtgtgaagct ctttttgaat atagactact
    42181 gtatttgtag gagggttagt atgcaggtaa aaacaaagca aggtgttttt tatgttaacg
    42241 cagactacac cgtcgtcgaa aaacaaggtg actatcctaa gctaacttgt actattccta
    42301 ttaagggaaa tgagacttgg atagcagatt gccaagaact tgaccgctta tacccagctg
    42361 gggaacaaga tgaatttatt attatcaatc ctattaaagt cactaagggg agttcgtatg
    42421 atttggaaat tacagcgata ggagcctttc attttgaatt tgtaaaggct cgtctatatg
    42481 aagaactacc agaacgaatg tatactttag attacttgct cgatctcctg tttaaagaca
    42541 gccgattcag ttataagcta caaggtgatt attctactag aaggttcagt ggcttcggag
    42601 atgataacaa actgacttta ttccatcatt taatggaacg atttcaaaca gaatttaaag
    42661 ttgttggcaa ggtcgtttta gttaacacaa aagtaggtaa agatacagga tttcagttcc
    42721 gctatcttag aaatatcaag gatacaaagt actcggtaga cgtaactaac ctgatgacat
    42781 acgttaaagg atatggagcc tggtttgatg aaaatgacca ttcaaaggga agattaattg
    42841 ttgattatga gagcccctta tccaaagagt atggcaaact tgatggtaag cccgttgttg
    42901 atgaacgaat gagtttaaaa gaaagtctta tcaaaaaatg taagctagcc gtagatcgct
    42961 ctgtatctgt cagcttaaca acgactttag tctctttaaa acaacaggat tatcaaggtg
    43021 cggcgagaat aggagactct atttggttta ttgacgaacg tatatctatt gaaaaaaaga
    43081 ttcggttcag cgtagtaaca acttactaca atgcatatga tgatatttta aagcaggacg
    43141 ttactttagg tgataaagat acctactctc gatatcaaag tttagaaaac tcttctcaaa
    43201 cagagacaaa tgattttcaa aaagcgatga gtagcaaact tgcagaagtt caagatgatg
    43261 ttaaaaagac gcatatttta gtatctggca ctactaggat tttcttttct acagagtttc
    43321 ctcaggataa tcctaaggga actataaaag aagatgacat tttgtaccgt aatcacgatg
    43381 ggacaacatt gatgtacagg tggaatggtg ttcaatggga attagtcccg ttggtaaacg
    43441 atccagatcg ttggcgtgag gaactggaga aacaaatctc tgaggctgtc gaaaagctca
    43501 aacaagagca aaaagtaatc aaccagagaa ccgataaaga gctcgaagag tttagagata
    43561 cgctcaaaaa cctatcttta ccagaggaag ccattaaaaa aatcacagag gctatcaaag
    43621 ttgatgatat cccgtcgatt aaacagtcat ttgatgactt aaaaaataaa gtcagcgaga
    43681 caagcgagac cgcacgatta aacgctgaga ttatcgggac agatggcaag acccgctaca
    43741 acaaaaattt gctagtcggc gaccc
//
LOCUS       DARYYD010000013        43220 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.013, whole genome shotgun sequence.
ACCESSION   DARYYD010000013 DARYYD010000000
VERSION     DARYYD010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43220
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.013"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(296..655)
                     /gene="rplT"
                     /locus_tag="TV188_000630"
     CDS             complement(296..655)
                     /gene="rplT"
                     /locus_tag="TV188_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEL1534009.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AAAFTALADAAKAKLGK"
     gene            complement(716..913)
                     /gene="rpmI"
                     /locus_tag="TV188_000631"
     CDS             complement(716..913)
                     /gene="rpmI"
                     /locus_tag="TV188_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEL1534010.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAFTSHRFHGKTKKQRRHL
                     RKAGMVHAGDFKRIKAMVTGL"
     gene            complement(953..1483)
                     /gene="infC"
                     /locus_tag="TV188_000632"
     CDS             complement(953..1483)
                     /gene="infC"
                     /locus_tag="TV188_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEL1534011.1"
                     /translation="MKIIAKKDLFINDEIRVREVRLVGLEGEQLGIKPLSEAQSLADA
                     ANVDLVLIQPQAVPPVAKLMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPVIDKGD
                     FETKLRNGRKFLEKGNKVKVSIRFKGRMITHKEIGAKVLADFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPISDKK"
     misc_feature    complement(1498..1620)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(1644..2324)
                     /locus_tag="TV188_000633"
     CDS             complement(1644..2324)
                     /locus_tag="TV188_000633"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEL1534012.1"
                     /translation="MKAIRIAIDGPASSGKSTVAKIIAKNLGYTYLDTGAMYRSATYI
                     ALKNGYHKEDVNLILQELAKRPISFKKAADGSQLVFLGDQDVTMAIRQNDVTNNVSWV
                     SALPEIREELVNQQRRIARTGAIIMDGRDIGTVVLPDAELKIFLIASVEERAQRRYQE
                     NIEKGIAADFDTLKAEIAARDYKDSHRQVSPLKAADDAIIFDTTGITISAVVQFIQEK
                     AEKIIDMA"
     gene            complement(2339..2836)
                     /locus_tag="TV188_000634"
     CDS             complement(2339..2836)
                     /locus_tag="TV188_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEL1534013.1"
                     /translation="MAKEPWEEKIVDDNKATRTRKSRGALISTPWLTALLSVFFVIIV
                     AILFIFFYTSNSGSNKQNETTGFYGASTQKKTTKKVSSKPKTKPKASSNSSAASDTTS
                     PSKTETAPSTEAAGKTITVLAGEGATSIAARAGISVEQLQALNPDHMTQGYWYANPGD
                     EVNIK"
     gene            2885..3082
                     /locus_tag="TV188_000635"
     CDS             2885..3082
                     /locus_tag="TV188_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEL1534014.1"
                     /translation="MKVSILPEKCIACGLCQTYSALFDYHDDGIVKLAQSDESSQLID
                     PNDHDAILAVKSCPTKALTLE"
     gene            complement(3069..3557)
                     /locus_tag="TV188_000636"
     CDS             complement(3069..3557)
                     /locus_tag="TV188_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HEL1534015.1"
                     /translation="MIKLFGKVRYHWQPELSWSIIYWSIAVAPIFIGLSLLYERTEIP
                     SRVFVLFALFAILVGLGLHRYFVIENNGVLKIVSLKLFAPHRLMIASITKIEVTKSTV
                     CLFVGDKSYLFYMRKWPKKYFLDDLAINPYFKGEVILLDNFIKLDYFEAYQYEKKPLT
                     RG"
     gene            complement(3602..4825)
                     /gene="pepT"
                     /locus_tag="TV188_000637"
     CDS             complement(3602..4825)
                     /gene="pepT"
                     /locus_tag="TV188_000637"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEL1534016.1"
                     /translation="MTYETLLERFLNYVKINTRSNPASTTTPSTKSQADFALTVLKPE
                     MEAIGLQDIHYNPANGYLIGSLPANSSKLTRKIGFIAHMDTADFNAEGVAPQIIESYQ
                     GGEIKLGQSGYSLCPEDFPNLNQYLGQTLITTDGTTLLGADDKSGIAEIMTAIEFLVA
                     NPQIEHCDIKVAFGPDEEIGVGADKFDVNAFDVDFAYTIDGGPLGELQYETFSAAALE
                     LKVLGRNVHPGTAKNQMINALQLAMDFHSQLPVDDRPEKTDGYQGFYHLHSMSGTVEE
                     AQASYIIRDFEDSSFEARKAFVTQLAEEMNSQLGAERVFVTVTDQYYNMKKVIEKDMT
                     PVNLAKAVMEDLAIKPVIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEFVSLQT
                     MEKAVDVILGIVQKA"
     gene            complement(4995..6014)
                     /gene="galE"
                     /locus_tag="TV188_000638"
     CDS             complement(4995..6014)
                     /gene="galE"
                     /locus_tag="TV188_000638"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1534017.1"
                     /translation="MLGSILVTGGAGYIGSHTCVELLAAGYDVVVVDNLCNSNPKSLA
                     AVASIAGREVTFYQGDIRDQQLLTDIFSKHPIVSVIHFAGLKAVGESSRIPLDYYDNN
                     ISGTLTLLKVMTAFNCKKIIFSSSATVYGDPHTVPILETFPLSVTNPYGRTKLMLEEI
                     FKDLYASDNEWHIVLLRYFNPIGAHESGDLGEDPKGIPNNLLPYVSQVAVGKLDCVGV
                     FGDDYETKDGTGVRDYIHVVDLAKGHVAALAKFAEEPSLSIYNLGTGTGYSVLDIIEA
                     FSQVVGRSIPYKILPRRQGDIAACYADASKAKKELNWTAEYGLERMCTDTWRWQSKHP
                     NGYED"
     gene            complement(6082..8451)
                     /locus_tag="TV188_000639"
     CDS             complement(6082..8451)
                     /locus_tag="TV188_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1534018.1"
                     /translation="MLDMILFSLSSLYLSIFAVSKNTLNKGAYGSWLVLVLIAGMACL
                     LIKHASSKLLIVSVAVSSYYAVANSYITLAINKNNSRFTISNRTIQEMLLSLAALVSL
                     LILGVLLKKYLFKKDYQSNRGIQVILLSQAFSVLTLNSSLFKTVIKQNDYWPLDSQSN
                     LVSLNLFKYSFCSYMLTFVVYYLIVTAFIEVLSKRWGLRLALVTSLFLGIIFNYFIQA
                     GITAYGDFHGAVIIPGATLFQVLVLTLFFVLVFLLINNYIIALFVNTVIGALISIVNI
                     EKYKQRSEPLLFSDLKWIKEIKFFLNYISLTQIISIILILVLSGLLIYVLYKRYFREK
                     ILSALYLRLMSIGSILLVFASILFVFSQNKDGEIKKGIPVLSSVYNVFDIDWYGLTTN
                     ARFQSLSFVWFKQVTTSTINQPSGYSKSAMQKIYQKYQARAADINKQRHQRISDQTVI
                     YILSESFADPARISGVQLAKDPIAEIHHIMETTTSGLMTSDGYGGGTANMEFQSLFGL
                     PKYNLNPTVSILYSDVFPKLKFSPAISNAFSPKDRIVLHLASANNYSRKIVYNKLGFD
                     TFIATEDSADKPKHLIRMSSSYSDESTYDNILDQLNPKRSQFFSVITMQNHGPWYTEL
                     RDVDVSLAGLDQSETDSLQSYVNLLSITDKSTKAFLSALEKVDKPITVVFYGDHLPGF
                     YPDQVFKNDEEVKYLTDYFIWSNHQTNKLARPRVNSSDFTSLLLEHTDSKVSPYYALL
                     TDVLDTRNSDDSQLTAAQKQVASDLKLLEYDLIEGKGYINAYPDFFKMK"
     gene            complement(8531..9694)
                     /locus_tag="TV188_000640"
     CDS             complement(8531..9694)
                     /locus_tag="TV188_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1534019.1"
                     /translation="MKTIAIFSGFTSPHLGGVERYTEKIAQQLVSLGYRIIIVTSNSH
                     QLSPIERDQAITYYRFPSKQLFKQRYPILDKNDLYHSMLAELMEERIDFVICNTRFYL
                     TSLMGLKLAKRKAIPSIVIEHGGGYVQVGENVKGHQLLDLFAKVYEHVITFFVKAYQP
                     DFYAVSKRSMAWLKTFGIKAKGVIYNSVDSDLYEVFKSKAYLPALQDKVIITFAGRVI
                     KEKGILLLLEAFEQLTYKDRAVLVVAGDGPLLASLRDSYKEDQSIIFTGKLNFAETMS
                     LLSQSDIFVNPSIYAEGLPTAVLEAGMLKCAVLATDRGGVKEVITSPSQGIIIDDTVS
                     DIKRQLDHLIEHKEKRCDLQEAIHQQVLSGFTWEVTVRQLVTEVIASESESNV"
     gene            complement(9708..11192)
                     /locus_tag="TV188_000641"
     CDS             complement(9708..11192)
                     /locus_tag="TV188_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2142 domain-containing protein"
                     /protein_id="HEL1534020.1"
                     /translation="MLDTLFDKLQKASKALLVLLGAFLVLLLLYTQSTDLPIKFLAIL
                     VAIAALLIIFLPSNMEYATVLIIVVMGSVSAFISPINDIPDERVHFARALYLSEGNLN
                     LTNDDSKLLVTDDINLMDHNNGKPLRFQLWSRDHTDEAISFKEIRSTNGYYNFAYIPQ
                     VIGLFIGRSLGLTMGLSYLLGRLCNVLAYAILVFVALRLLTAGKQLLAVGSLLPMNIY
                     LAGSYNQDCVSIGLIILTISLFVQMATTEKIPLSKLFWYTLLCSIITFTKLPYILLIL
                     LLLFIPSRQFGAKASRTFLLKLLSILTVLVVTVFWLKVYGQIKSPQVDMADFLQKVNA
                     KEQLLTVLRNPIVYGFMLLRHTLAHILNPSGIYMFGPLSYGMVELMPISMVYYFAVVI
                     TNANKLQLPTLSRFGMGLMSLGIIGGITFSLYLTFTPVGDLNVLGVQDRYFLGVIPLV
                     LVLLASNNKYLEKAQGLLSNKQVLIGSLLLILGMITRTMLQYYT"
     gene            complement(11196..12437)
                     /locus_tag="TV188_000642"
     CDS             complement(11196..12437)
                     /locus_tag="TV188_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HEL1534021.1"
                     /translation="MKTSSRIQSDQSIFIWNVLGTSSTALISVILLMIVSRVLSKSAS
                     DTFSFAYAIGNQLITIGLFQIRNFQSTDILHKYRFKDYFYTRLVTCFLMIAISVLYIY
                     LGSYSGFKGLVIWLICLYRCTDAISDVFQGMFQQRERLDIAGKSLFYRNMLVILGFTL
                     CLVLTKQLVLSLIVICLISVACIVLFDITPSVSFTSLERRIDAQSILGLLKESFPLFL
                     NGFLLIYIYNQPKFVLEQLYSKQLIPAGVQTEFNILFMPIFMINLIFLFLRPMITQLA
                     IYHSKEDKKSFAQLERRLSLVLLLASLAILLASYFVGLPVLSLVYGIDLRHYQLDFML
                     LIFGGIISTFATYIDNLITIIRKQHLLVIPYVVSFISSLAITGSLARSFGVIGVTYGF
                     IISMMIWLLLSYGLYIMEKRK"
     gene            complement(12421..12777)
                     /locus_tag="TV188_000643"
     CDS             complement(12421..12777)
                     /locus_tag="TV188_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2304 domain-containing protein"
                     /protein_id="HEL1534022.1"
                     /translation="MFIGLQLILIIVALLTAMFILDSIRRSKILIEDSFFWLFFSLIV
                     LLLSLFPNAAVYFSRLLGFESPANFVFLSIIFLLIINQFFITQKLSRTEIKLKKMIQY
                     LALNEKEKQEEDENQQ"
     gene            complement(12782..13471)
                     /locus_tag="TV188_000644"
     CDS             complement(12782..13471)
                     /locus_tag="TV188_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1534023.1"
                     /translation="MKKDLLVMIPAYNEEESIEKVVENIKRHFPQYDYVIINDGSSDR
                     TSEICHHNHYNIIDLPENLGLSGAIQTGFKYAFKKGYAKALQFDADGQHLPEYIEALS
                     DSINAGADCVIGSRFVSAEKNRSLRMIGNSLISFFIKLTTGKRITDPTSGMRMFNQEL
                     IRIFATNINYTPEPDTISYLIRQGYRVSEVQVQMNDRLAGQSYLTLSRSIKYMVHMFI
                     SIILIQNFRKR"
     gene            complement(13501..15246)
                     /locus_tag="TV188_000645"
     CDS             complement(13501..15246)
                     /locus_tag="TV188_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-Rha alpha-1,3-L-rhamnosyltransferase"
                     /protein_id="HEL1534024.1"
                     /translation="MKRLLLYVHFNKYHKVSDHVYYQLEQMRALFSKIVFISNSDIHQ
                     EDLEQLEQRHLMDQFIQRHNKGYDFAAWHDGMKALGCEHLVDFDSITIMNDTCFGPLW
                     DMKPYYLKYEADEAVDFWGMTNNRATKAFKEHIQSYFISFKKSLVHSKEFRQFWENIV
                     ELTDVQDVIHNYETRITTVFVEAGFRYKTVFDTTKEDSSSMLHADFSYYNPTAILKHH
                     VPFIKVKAIDANQHIAPYLLDFIDQKTTYPASLIVDHMSQVHPPDAKYLLAHKYLPEQ
                     PISIDQSKKIAVHLHVFYVDLLSEFLEAFSHFHFDYDLLITTDSKAKKAEIKEILRES
                     GASADILVTGNIGRDVLPMLTLKERLSQYDYIGHFHTKKSKEADFWAGQSWRTELIDM
                     MVKPADQILTALAADAIGIVIADIPSFFRFNKIVDAWNEHLIAPEMNQLWQAMGLTKR
                     IDFQTMDTFVMSYGTFVWFKYDALKPLFDLDLSEADIPAEPLSQNSILHAIERLLIYI
                     AWDRHYDFRISRNEKLLTPFIDNKLLNLREGSVPHTYVDFDYMGGIKGALKYIVIGPA
                     KAIRYIIKRLLKRRV"
     gene            complement(15243..16250)
                     /locus_tag="TV188_000646"
     CDS             complement(15243..16250)
                     /locus_tag="TV188_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1534025.1"
                     /translation="MKKVSIICTNYNKGPWISEALDSFLAQQTSFDVEIIVIDDASTD
                     YSRQILMDYQASFPDRIRLIVNEVNLGIARTWVKACLEAKGQYIARCDGDDYWTDTLK
                     LQKQVDLLDSSPDSKWSNTDFDFVDTDGKLIQSNAFESGFTPLTDTYEKMLALKGMTM
                     SSTWLVEADLMRAVNQRIDLETSDDTFDIQLELFQSTSLAYLKDSTTVYRMTDNSDSR
                     PAAEEKMLGRIQGLLETQLSYLSKYPTANMEAIAKALLKQDAKNEIRIHQLSHTIHQL
                     RQTLADQEALQAEKIDQLQQQLDHQRQEVEALTHQYNCVVTSRRWRYLSKLLELFRRK
                     K"
     gene            complement(16271..17479)
                     /locus_tag="TV188_000647"
     CDS             complement(16271..17479)
                     /locus_tag="TV188_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534026.1"
                     /translation="MANKEIAVTVDHVSKSFKLPTEATKSFRTALVNRFKGIKGYTEQ
                     HVLRDISFDVYKGDFFGIVGRNGSGKSTLLKIISQIYVPEKGQVTVEGKMVSFIELGV
                     GFNPELTGRENVYMNGAMLGFTTEEVDDMYDDIVDFAELHDFMNQKLKNYSSGMQVRL
                     AFSVAIKAQGDVLILDEVLAVGDEAFQRKCNDYFMERKESGKTTILVTHDMGAVKKYC
                     NRAVLIENGLVKAYGEPFDVANQYSVDNTELKNAEQGAAAEPVSDLASQLEVRLTSKP
                     SLSPDEPISFEISYHVLKDEPTYVAFSLTDIDRNIWVYNDNSQDQPTSGPGHKNISYQ
                     CQLSHLNDIKLKLEVTVRDQNGQMLLFLTANHSPLVVLQRNDIAPDDLSALDSASGLY
                     QRNGSWLINQ"
     gene            complement(17479..18282)
                     /locus_tag="TV188_000648"
     CDS             complement(17479..18282)
                     /locus_tag="TV188_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1534027.1"
                     /translation="MELLSKKNRILLKELVKTDFKLRYQGSAIGYLWSILKPLMMFTI
                     MYLVFIRFLRTGGDVPHFPVALLLANVIWSFFSEATSMGMVSIVSRGDLLRKLNFSKH
                     TIVFSAVLGALINFSINLLVVLVFAAINGVTLSPHAYLALPLFVELAVLTVGVALMLS
                     TVFVYYRDLAQVWEVLLQAGMYVTPIIYPITFVFDRHPLAAKILMLNPLAQIIQDLRY
                     LLIDRANVTIWQMSTNWCYIIIPYLIPFVLLALGVAVFNKNAKKFAEII"
     gene            complement(18282..19217)
                     /locus_tag="TV188_000649"
     CDS             complement(18282..19217)
                     /locus_tag="TV188_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1534028.1"
                     /translation="MKINILMSTYNGARFLAEQIQSIQRQTVQDWTLLVRDDGSTDKT
                     LAIIQAFAKKDPRICLINADVQENLGVIRSFHTLLTYEKADIYFFSDQDDVWLDNKLE
                     LTLAEAQKHKISEPLLVYTDLKVVNQDLEVRHESMIQTQSHHANTQLVQELTENTVTG
                     GTMMINHALAEQWVSCEHVVMHDWYLALIAAAQGELVYLDVATELYRQHDANVLGART
                     WSKRLKQWRKPHKLIEKYWWLIVSSQHQARQLLDLQLNPADRRLIEAYVGLLDRPFYQ
                     RLSDFKAYGFRKNRAFHTLVFMALIMTKFGYRRKE"
     gene            complement(19207..20361)
                     /locus_tag="TV188_000650"
     CDS             complement(19207..20361)
                     /locus_tag="TV188_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HEL1534029.1"
                     /translation="MQDVFIIGSRGLPAKYGGFETFVEELVTNQTNKSITYHIACLSD
                     SKHKEHFVYKGADCFYINPPKLGPARVIAYDMMAISHALAYIDRYHIQKPIFYVLGNT
                     IGGFIAPFAKQIHQRGGRLLINPDGLEWKRSKWSKPVQQYLKYAEKQMTKHADLVISD
                     NIGIEAYIKKSYPWAKTTFIAYGTEIGRSCLSTSDEKVRTYFQTFEITENQYYLILGR
                     FVPENNYETAIREFMASSTQRDLVIICNHDKNPYFERLVSATGCDKDARVKFVGTQYD
                     KQLLAYIREHAFAYIHGHEVGGTNPGLLEALAHTQLNLVLGVTFNQSVAKTAALYWTK
                     EKGSLTGLINRVDQKESFADLGERAKQIIAKEYTWEKIVGEYEALFLDED"
     gene            complement(20486..21334)
                     /gene="rfbD"
                     /locus_tag="TV188_000651"
     CDS             complement(20486..21334)
                     /gene="rfbD"
                     /locus_tag="TV188_000651"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEL1534030.1"
                     /translation="MILITGSNGQLGTELRYLLDERSVDYVAVDVAEMDITNATKVEE
                     VFAQVKPSLVYHCAAYTAVDAAEEEGKALNEAINVAGTEHIAKACERYGATLVYISTD
                     YVFDGQKPAGQEWLETDTPDPQTAYGRAKRLGELAVERYTKQFYIIRTAWVFGHYGKN
                     FVFTMQNLAKTHSRLTVVNDQHGRPTWTRTLAEFMCHLADNRKPYGYYHLSNDAKEDT
                     TWYDFAREILKETAVEVVPVDSSAFPAKAKRPFNSTMNLDKAKATGFVIPTWQEALEA
                     FYKQQQ"
     gene            complement(21476..21814)
                     /locus_tag="TV188_000652"
     CDS             complement(21476..21814)
                     /locus_tag="TV188_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEL1534031.1"
                     /translation="MTETLKYTEEQVAAIKDRILEALGTVIDPELGIDIVNLGLVYEI
                     RFDDNGHTEIDMTLTTMGCPLADLLTDHIHDAMRDVPEVTKVEVKLVWYPVWSVEKMS
                     RYARIALGIR"
     gene            complement(22112..23221)
                     /gene="rpoD"
                     /locus_tag="TV188_000653"
     CDS             complement(22112..23221)
                     /gene="rpoD"
                     /locus_tag="TV188_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEL1534032.1"
                     /translation="MAKEKEITTFNVQIAEFIRHHKKEGTATDDEVTEKLVIPFTLDA
                     DQIDDLLERLTDGGISITDKEGNPSSKYVVEEPKPEELTDEELIGSNSAKVNDPVRMY
                     LKEIGVVPLLTSDEEKVLAVAVAAGDMEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMEMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRVVLREQLDEVLDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRHPSRSKQLRDFIED"
     gene            complement(23230..25044)
                     /gene="dnaG"
                     /locus_tag="TV188_000654"
     CDS             complement(23230..25044)
                     /gene="dnaG"
                     /locus_tag="TV188_000654"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1534033.1"
                     /translation="MGFLWGGDGLAIDKEMISQIKHNVNIVDVIGEVVHLSRAGRHYL
                     GLCPFHKEKTPSFNVIEDRQFFHCFGCGKSGDVFKFIEEYRQVPFLESVQIVADKAGM
                     AVTVAPSQTSLSQKQHPHQALIDLHEDAAKFYHAVLMTTKIGQRAKEYLYQRGLDDQL
                     IEYFRIGLAPNEMDYLYQALSKKYTEAQLTASGLFHVSEQSNAIYDAFRHRIMFPLCD
                     DKGNMIAFSGRIWAREDIEKQQAKYKNSRATVLFNKSYELYHLDKAKPIIAKTHEVFL
                     MEGFMDVIAAYRAGYGNTVASMGTALTPEHVRHLKQLTQKVVLTYDGDDAGQNAIAKS
                     LELLADFQVEIVKIPNRMDPDEFVQQHSPEALAELLQHSRISSVEFLIDHLKPENMDN
                     LQSQIAYVEHISQIIAQAPSITAQNSYINKVADLLPDFDYFQVEQSVNALRLQDRQSL
                     QQGQASQPKASLVTLPINKSMTALAKTESHLLHRLLHHDYLLNEFRHRPDFYFDTPAL
                     QTLYEQLKATGQITSYDLSQLSEEVNQAYYRVLEENLPDEIASGEIEDILSRQMTLLK
                     QRELHRQGKQIRESSSKGDHQMALEALERFIAEKRKME"
     gene            25291..25665
                     /gene="mscL"
                     /locus_tag="TV188_000655"
     CDS             25291..25665
                     /gene="mscL"
                     /locus_tag="TV188_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEL1534034.1"
                     /translation="MLKELKAFLFRGNIIDLAVAVIVGSAFSAIVTSFVNDIITPLIL
                     NPALKAANVENIAQLAWNGIKYGSFLSAIINFLIVGTSLFFVVKVAQKAMPKKGEEEP
                     AKPKTPTQEELLLDIRDLLAKK"
     gene            complement(25891..26067)
                     /locus_tag="TV188_000656"
     CDS             complement(25891..26067)
                     /locus_tag="TV188_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEL1534035.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVTKAGTLQESRKREFYEKPSVK
                     RKRKSEAARKRKKF"
     gene            complement(26222..27034)
                     /locus_tag="TV188_000657"
     CDS             complement(26222..27034)
                     /locus_tag="TV188_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEL1534036.1"
                     /translation="MNMKRLLVGALAMVSVFALAACGQANKTSLQDRIQEKGKLVVAV
                     SPDYAPFEFKALVDGKDTIVGADIELAQAIADELGVKLELSAMNFDNVLSSLQTGKVD
                     IAISGLSYTKERAKVYDFSEAYYETENAILVKASDAKHYANKDSLVGKKVAVQKGSIE
                     EGLVKEQLNKANCVSLTVMGEAINELKSGQVQAVDLEAPVAAGFLAQHKDLALAPFKL
                     QASDGDAKAVAMPKGSDDLRQTINKVIKQLNKDGKYKAFIQEAALLTGNAVE"
     gene            complement(27102..28217)
                     /locus_tag="TV188_000658"
     CDS             complement(27102..28217)
                     /locus_tag="TV188_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HEL1534037.1"
                     /translation="MKLPVFGVEEWLNQHEKRAVYDIAGSSIASLTLEELFDLTQEQP
                     QAFYQQLHQKPLDYGWIEGSPDFKQAVAGLYQQQKARNILQTNGATGANFLVIYALLE
                     AGDHVIAHYPSYQQLYDIPASLGVEVDYWQIREEQAWLPDLNELGAMIRPNTKMIMIN
                     NANNPTGAYMTKPYLEELINIAREHDIYLLSDEVYHSFTSDHLLAVADLYDKGITVNS
                     MSKTFSIPGIRVGWVAASETICDQLRLYRDYTMICAGVFDDMVASLALKHADKLLQRN
                     QAIIRTNLAILEDWITGEARASYHRPNEVSTAFVRLDIDEDMEAFALRLLEDYGTLVV
                     PGNRFNQANHVRIGYCCQPQVLQAGLSRLSQCLKNIQ"
     gene            complement(28487..32128)
                     /gene="addA"
                     /locus_tag="TV188_000659"
     CDS             complement(28487..32128)
                     /gene="addA"
                     /locus_tag="TV188_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEL1534038.1"
                     /translation="MRIDEGFLTPEAIARLQQEEALSDKTHKRTAQQIEAIYSSGQNI
                     LVSASAGSGKTFVMVERILDKILRGIPVDCLFISTFTVKAATELIERIEKKLHTAIAE
                     TQDYQLKAYLNDQLQALSQADIGTMDAFAQKLVHQHGYVLGISPHFRIIQDKAEQDIL
                     KREVFRQVFEDYMSQTDNKAFIQLVQNFSGRRKDSSAFREIVDSIYAFSQSTANPSSW
                     LAEVFLRGSKTYTSFTDIPDQAVDALLACMQDTADQLRDLTDMEGYAQTTKAGKLTAK
                     YTKHLKMIDSLYEWALHFDSLYGKARLGQLAQELTALLPSGADITVAGHKYPIFKSLQ
                     EQLVRFRHLETILAYQQESLPLLEVLQAFVISFSEAYLAAKMQENAFEFSDIAHFAIE
                     ILQQAPDIRQAYQGHYHEVMVDEYQDNNHMQERLLELLSNGHNRFMVGDIKQSIYRFR
                     QADPQIFNQKFKDYQSNPEHGKLILLKENFRSQSEVLNVTNAVFSRLMDESLGEITYD
                     DKHQLVAGSEGQRQPYPNNRAQLLLYDTDQVQEGTEEALANDGISAGEVILVAKEIIR
                     LYNEEKVAFEDITLLVSSRTRNDTIFQVFNQYGIPLVADGGQENYLKSVEVMVMLDTL
                     RSINNPLNDYALVALMRSPMFSFDEDQLARISLQGSSQKQPQAFYDKLSNSLRGQGEH
                     PELIGQELMTKLADFDGTLRDWRQFAKLHSLYELIWKIFNDRFYFDFVASQPKAEQAQ
                     ANLYALAIRADQFEQSGYKGLSRFIGMIDKVLETQNDLADVEVERPKHAVNLMTIHKS
                     KGLEFHYVFILNCDKRFAMADLQAPIILNRDEGIGIKYVANVKELLREEKLASLKVTM
                     ETLPYQLNKQQLRLATLSEQMRLLYVAMTRAEKKVYLIGKASKEKVQEKTADNSSEGR
                     LALASRERLLSFQDWLLAIAATFSKEDLFIDVRFVDDSDLTPEAVGQLRPSGLLQADD
                     LKDNRQTEDIARALDMLDKVSELNASYQAAIELPTVRTPSQLKTLYEPLMDTDGVDII
                     DQPYHRPKTFELPDFSKKKAVEPSQVGSSLHELMQRIPMSDQVTAGDIEQTLQLVSAD
                     AEVKARLDIEKVTSFFATTELGQLLQEHHQRLHREAPFAMLKKDSLSQEQYVVRGIID
                     GYLLFEDRIVLFDYKTDRYQQSAELKQRYQQQMDLYAEALSQSYGIARIEKYLVLMGG
                     SQLEVVRLA"
     gene            complement(32118..35339)
                     /gene="rexB"
                     /locus_tag="TV188_000660"
     CDS             complement(32118..35339)
                     /gene="rexB"
                     /locus_tag="TV188_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEL1534039.1"
                     /translation="MKLLYTEISYSMTEILVKEARAYADKGYRVFYIAPNSLSFEKER
                     SVLALLPEQGSFAITVTRFEQMARYFTLAKAANRQALDDNGLAMIFYRVLMQLQEDEL
                     KVFHRLRTDQAFIAQLVELYKELQAANLTAFDLTTLDRPEKQEDLITIMTKAEQLIAQ
                     GDYDQSSRLAQLAEAIKSKSLDDELRQTVLVIDGFTRFSAEEEQLLALLNEACEEIVI
                     GAYISQKAYRLAFTKGNLYEASLAFIQQLAQQFQTKPIYTTSEKVFDVSFSRLTQLLE
                     ANHDYSKLDWQLSAKDKSKVVIWQALNQKEELEHVAKAIREKLYQGYRYKDMLVLLGD
                     VASYQLQIGPIFEKFEIPYYIGKQEPMSAHPLVQFVESLERGRRYNWRREDIVNLLKS
                     GLFGRFQEGELDQLEQYLVFADIQGFTKFSRPFTLNSSRQYPLPLLNQLRLAVVTPLQ
                     QLFKSQKQLGASLLDKLMTFFKTIQLADNFEALAGSRRETDREKDEEVWKAFTGILET
                     FYQVFGQEKMTLADCLALIKMGMQTAHYRTVPATLDVVSIKSYDLVEPHSKPFVFAIG
                     LSRSHFPKQTKNTSLISDQERASINEQTASYQRLDVPSFENIKKNHQTALSLFNAATQ
                     ELVLSLPTSLTNSSDDVSPYLKELIALGVPVIEKGKNRLSHSAADIGNYKALLSRLVA
                     INRQGIADDMTSEDRNFWTVALRYLKRRLADEQLSLPAFEHHLTTKPVAPEVIETRFS
                     SQQPLNLSSSALTVFYNNQYKYFLKYVLGLQEPESIHPDARIHGQYLHRIFELVTKDR
                     SNAAFDQKLGAAIAAVNQQSAFQQVYQADAEGRYSLEVLKGIAYSTASVLDLNQGLQI
                     TKQEEAFELALGQQVLIRGVIDRIDQLADGRLGIVDYKSSARVFDIVAFYNGLSPQLV
                     TYLAALKNKGQGLFGAMYLHMQEPRLSLSDFKALDDQLVAAAYKELTYKGIFLAQAKE
                     YLANGSYHLNNTLYETDELETLLAYNEQLYLSAVKQIKTGHFLINPYTADGKSVQGDQ
                     LKAITRFEADLDLGYARRLVVLPTKERRQAFLTRMNEEIKHED"
     gene            complement(35548..36948)
                     /locus_tag="TV188_000661"
     CDS             complement(35548..36948)
                     /locus_tag="TV188_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1534040.1"
                     /translation="MIVQLLFLVLKYSQYLFLAFLIAYASFLLLSLIVGTIHLYERRQ
                     QAPVGGDVSLPPVSILVPAYNEELTIIETVESLLMLDYDCYEIIVIDDGSTDHTAKLL
                     KEQFHLEAVTCSINQRIPTRPLKAVSQKQLKHIKLTLLEKANGGKGDSLNLGINAAQY
                     DYLLCMDADSMLQEDSLKRIAKTAAKDPSVIAVGGMVKVSQGVALAAGRIVDYHLPRQ
                     LISCAQAIEYDCAFFGARVLLDQAAGNLIISGAFGLFKKELAIAVDGYDTGTLGEDME
                     LVMKLHFFCHNNKIPYRIGYETDAICWSQAPSRLKDLCRQRRRWFLGLYQCLKKYLQF
                     FVSCRFKATVLISYVLYLLFELLSPFIEAFGVIIIVLSLLCHQLNTTFFVSLMLLYIC
                     YCVLIALTSFLNRVYLQNNSSITLFDMAWVIYAAIYQCLVLHTVLTLIKVSSFIGYQR
                     KKNAWGQITRDKHRAA"
     gene            complement(37090..39231)
                     /locus_tag="TV188_000662"
     CDS             complement(37090..39231)
                     /locus_tag="TV188_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534041.1"
                     /translation="MKKYLIFVGLLLSVIGLSYYCCDIDGRLYLPVSNQSAIRTVFYT
                     KDKRIYDQKGSPYLIKGVDVESSIAGYRRRDLSVDEKTYYRWFKQIAAMGANTIRVRV
                     IMPVTFYHALRRYNDRASHPLYLLQGFRIDAYHDNSSISALDKAYLGTLLREARASVD
                     VIHGRKRIWHSDLGLQHYDQDMSKWLLGYIVGDDWYSGTIAYTNHQNHAKPVGFKGRY
                     YATTPQANRFEAILAEIMEEITSYESRKYGWQHLVSFSNTPQSDPFVYQDPFASQAAK
                     YVQLTIENIKPSAKVKAGLFASYKLLDCHSAYRDYLLFDRLGLTDRLVGDIKRMPLYQ
                     GYVKLLTSYHRVPVVVTGYGYSTARGVDQMISTSSPLTEKDQGERLMADYTAFIASGC
                     CGATIHSWQDDWTARSWNTSFATNKHQSFLWGDVQSKAQGYGLLTFEHAPRTHAIDGQ
                     KAADEWSRALTYKKNGQQLLVDQDEKYLYIAIESTKKQPLQRQWLIPLDITPKTGSRV
                     IEGFSARFDRFADFALVVDDHKGSRLLVQERYHATDANYLRQINGKDFYVFPPNKHTP
                     RFTMVDMVVRNDGIFAAIDQVPIAKRGLKRYPTGQLKQGNGKRGSAHFDSQTDISFGE
                     RLIELRIPWQLLNFSDPASNKIHDDYFEHYGVEELAIEAIAIGFAPLKESKVIAMVEY
                     PLLSWERPRVREVLKTSYQQVQAVWQEKRRR"
     gene            complement(39238..40671)
                     /locus_tag="TV188_000663"
     CDS             complement(39238..40671)
                     /locus_tag="TV188_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HEL1534042.1"
                     /translation="MKEKTIYVIVLVCLLLAAICGIGFPKTSAKRIHHHLQTVKKSSR
                     STGEFSSHLPIISIDTHHQQIPEQREYEGETKRQKTIKTTVSLRDQLDREHSLSESPR
                     LSLTALIAYRGNSSRHFDKKSLKLRFINKRAKPKAVSLAGMSKESEWVLHGPFLDRTL
                     VRNYLSYNIAGEIMTYAPNVRYCELVVDHQYCGLYLAVESIEQGRHRVNIEKSDRKSD
                     KTPYILVWDRRHKAKQALDHYVSYTNQAGLSSLDIKYPSLHRLTPKQKQFIEKDISHI
                     EKLLYSYDLKQYTDYLDQESFADYFIINEFFRNIDAGKFSTYLYKDLRDKLKLVVWDF
                     NNAFDNQIEAPYDEADFTLSDAPWFCMLLKDPSFVKLVVTRYHQLRQNVLSTDYLIKY
                     IDATVAFLGPAIQRNYHKWGYVFTVPSRSDATNYLVPASRNYSSYEASVKQLKDFIRR
                     RGRWLDKHIETLYQYSAPSKNTNTLLE"
     gene            complement(40677..41354)
                     /locus_tag="TV188_000664"
     CDS             complement(40677..41354)
                     /locus_tag="TV188_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HEL1534043.1"
                     /translation="MKQLLRHVFEQRGTLSFQDVLLHIVAAALLSIVIYMSYAYTHTG
                     TAYSKKFNVSLMTLTVLTATVMTVIGNNVALSLGMVGALSVVRFRTAIKDSRDTVYIF
                     WTIVVGICCGVGDYTVAATGSSVIFMLLLLMGAVRNDNRLLLIVRCDKQMEIELERLV
                     FNYFSGKAIQSVKNTTSDDIEMIFELSRKDYDSTYQQANPLTEAVYQLGRVDYFNIVS
                     QSDDITG"
     gene            complement(41368..42063)
                     /locus_tag="TV188_000665"
     CDS             complement(41368..42063)
                     /locus_tag="TV188_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HEL1534044.1"
                     /translation="MNEVLRQEKKYLITIEDYYRLSHEFSKLLRLDAHSSSEGYVIRS
                     LYFDSLEDVDWQEKEDGIELRRKIRLRNYGSQSSFAKLEMKQKQGSNQKKRSLRLTRA
                     DAQLLIKGDKSILLTYPDRFAAECYSRMSMQLYQPKTVIEYQRKAFVAKENNIRITFD
                     HHIIGSETNADIFSDHLPQNYLLDPYLVILEVKYNGFLLSYIKKLLESVNGSELSASK
                     YCMGRAISKHYRF"
     gene            complement(42191..42826)
                     /locus_tag="TV188_000666"
     CDS             complement(42191..42826)
                     /locus_tag="TV188_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zf-HC2 domain-containing protein"
                     /protein_id="HEL1534045.1"
                     /translation="MKYDCELIQDLLPLYVDDTLSDYSRAVVEAHLTSCKDCQTDLAD
                     LRQDYSKVEEELQEYQAEVCAFSRFIRKQRQQMIVATISICLVTGILSSILTAHRIRA
                     PYDYVAIDVGEHTQLNKEGLLSTARTTAKDHVALVYKHKAQKVNGSFEISELQARKIQ
                     QQLKQAMLKEANATDISSRQLDQSQKRLSCNQDDQLVYIISTDGRIYYFGR"
     gene            complement(42816..>43220)
                     /locus_tag="TV188_000667"
     CDS             complement(42816..>43220)
                     /locus_tag="TV188_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HEL1534046.1"
                     /translation="ETFLKAYRNIAKFSGDSSIKTWLFTIAKNTFFTEIKKKKYENMS
                     MESLEIVDAKGHDEPLDKIARRELLEITLTIIFNLPEKMQAVFLARIYSGDSYEKIAK
                     DIGITVSSAKVLVFRARKHIKRQLREEYGYEV"
BASE COUNT        12765 a         9945 c         8177 g        12333 t
ORIGIN      
        1 ttttgcattt tattattttg gtgatggatt tgattaaaac tagaaatcat atatctcctt
       61 atatgatcat cacttgatgg actgctcaac tgtctgatac aagattaagc cctttcttct
      121 tagttaacag ctaccaaaga aaggtaaatt ggctccttta tactaaatta gagatagcta
      181 aaaacatctc aaatactctt gacaaaacgt catgactgtc ttatctagct agattagcta
      241 acataaggca ttaaaaatag acttagaagg tttctaagtc tacagtcgat ctctattatt
      301 tgccaagctt tgccttagca gcatcagcaa gggctgtaaa agctgctgca tcattcaccg
      361 ctaaatcagc aagcatttta cggttaactt cgatttcagc aagctttagg ccatgcatca
      421 attgtgaata tgacaagcca ttcatacgag cagctgcatt gatacgtgtg atccatagct
      481 tacggaagtc acgttttttc tgacgacggt cacgataagc atagtaataa gaattcatga
      541 cctgctcttt tgcagtacgg aacaagatat gttttgctcc ataataacct ttagctaatt
      601 tcaaaatacg tttacgacgt ttgcgtgata caacgccacc tttaacacgt gccattaata
      661 ttctccttca aataactctt ataattctag taaatacctg ttacaaccct taatcttaaa
      721 ggccagtaac cattgcttta atacgcttga aatctcctgc atgcaccata cctgctttac
      781 gaagatgacg gcgttgcttt ttagtctttc catggaaacg gtgtgatgta aaggcacgga
      841 agcgtttcaa accgcctgaa cctgtacgtt taaaacgttt agctgatgcg cggtgtgttt
      901 tttgttttgg cattttaata ttctcctctt aacatatagt gtaatatgac aattacttct
      961 tgtctgaaat tggtgcaagc tgcataaaca tttggcgacc atccattttt gctctttgct
     1021 caataatagc aatatcttga gttgcctcag caaaatcagc cagtacctta gcaccaatct
     1081 ccttgtgagt aatcatacgt cctttaaaac ggatagaaac cttaacctta tttccctttt
     1141 caaggaactt acgaccatta cgaagctttg tttcaaagtc acccttgtcg ataactgggc
     1201 taagacgtac ttcctttaca gttacaacgc tttgcttttt gcgttgctcc ttttgctttt
     1261 tttgatactc aaatttgaac tttccatagt ccataagctt ggcaacagga ggaacagctt
     1321 gcggctggat taaaaccaaa tctacatttg cagcatcagc taaagactga gcttcagata
     1381 atggtttaat gcctaattgt tcaccttcaa gaccaacgag acgaacttcg cgaacacgaa
     1441 tctcatcatt aatgaataga tcttttttag ctatgatctt cacctcttta tttttttaga
     1501 gaaaaacgaa agcggactta atgaaccaag cccgcacaca taatatcccg taggaatttg
     1561 acatgtaggg ccagacaacc taggtcgcaa ggcgagaagc tctcacttct gcttttctca
     1621 ttattgacat tctaacaaat aaatcatgcc atgtcaatta ttttttctgc tttttcctga
     1681 ataaattgga caacagctga aatcgtgata ccggtagtat caaagataat cgcgtcatct
     1741 gccgccttta gcggcgaaac ttgacgatga ctgtccttat aatcgcgtgc cgcaatctca
     1801 gcctttaagg tgtcaaaatc agctgcaatc cctttttcaa tattttcctg ataacgacgc
     1861 tgcgctcttt cttcaacaga agcaatcaaa aagatcttca actcggcatc aggcagcaca
     1921 accgttccga tatcacgacc gtccatgata atagcaccag tcctagcaat tcgtcgctgc
     1981 tgattcacca gctcctctct aatctctggc aaggcggaca cccaagaaac attattggtg
     2041 acatcatttt gcctgatcgc cattgtcaca tcttggtctc caagaaaaac cagttgtgag
     2101 ccatcagctg cttttttaaa agaaattgga cgctttgcca attcttgcag gattagattg
     2161 acatcttctt tgtgataacc attttttaat gcgatataag tcgctgagcg atacatggca
     2221 ccagtatcta aataggtgta gccaagattt ttggcaataa tcttggctac cgtacttttc
     2281 ccacttgagg ctggtccatc aatcgcaatt ctaattgctt tcatcttttc ctctttaatt
     2341 atttgatatt gacctcgtca cctggattgg cataccagta gccttgggtc atatgatctg
     2401 ggtttagggc ctgtaattgc tcaacagaaa ttccagcacg agctgcaata gatgttgctc
     2461 cttctcctgc taatactgta attgtctttc ctgctgcctc tgtagaaggt gctgtttcag
     2521 tcttagaagg acttgttgtg tcactagctg ctgagctatt agagctcgct tttggctttg
     2581 tttttggttt tgagctgacc ttctttgttg tctttttctg agttgatgcc ccgtaaaatc
     2641 ctgttgtctc attttgcttg ttactaccgc tgtttgacgt atagaagaaa ataaaaagta
     2701 tggcaacaat aatgacaaag aaaacactta acaaggcagt caaccaaggt gtgctaatga
     2761 gtgctcctct tgattttctt gttcttgtcg ccttattgtc atcaacaatt ttttcttccc
     2821 atggttcttt agccatgatt cttccccctt gttaatttaa caaaatcata ttagaataat
     2881 acctatgaaa gtatctatcc ttccagaaaa atgcattgcc tgtggtcttt gccagaccta
     2941 ctctgctctt tttgactatc atgatgatgg tatcgtcaaa ttggctcagt ctgatgagtc
     3001 aagtcaactc atagatccta atgatcatga tgccatctta gcagtaaaat cctgccctac
     3061 taaagccctt accctcgagt aagaggcttt ttttcgtatt ggtaggcttc aaaataatcc
     3121 agtttaatga agttatctag taatataacc tctcccttaa aataaggatt aatcgctaga
     3181 tcatctaaaa aatatttttt aggccatttt ctcatgtaaa aaaggtagct cttatcacca
     3241 acaaatagac aaaccgttga tttagtaacc tcaattttgg taattgaggc aatcatcagt
     3301 ctgtgcggag caaatagctt taaagatacg atcttcaaga caccattatt ctcaattaca
     3361 aaataacgat gcaggccaag tcccactaat atagcaaata aagcaaacaa gacaaaaaca
     3421 cgactcggta tttctgttct ttcatacaat aaggacaggc caataaaaat aggcgcaaca
     3481 gcaattgacc aataaataat agaccaagac agctctggct gccaatgata ccttacttta
     3541 ccgaataatt taatcatgct tttccatcac ctccaatccg ttctgagcat tttgggtgat
     3601 gttaagcctt ttggacaatg ccaagaatca catcaactgc cttttccatc gtttgcagac
     3661 tcacaaattc aaacctgcca tgcatatttt caccacctgc aaaaatattt ggcgttggaa
     3721 tccccataaa ggaaatcttt gagccatcag taccaccacg aatcggctcg ataactggct
     3781 taatagctag gtcctccata acagccttag ctagattcac aggtgtcatg tccttttcaa
     3841 tcaccttttt catgttatag tactgatccg tcactgttac aaatacacgc tctgctccaa
     3901 gctgactatt catctcctca gctagctgtg ttacaaaggc ctttctagct tcaaaggagc
     3961 tatcctcaaa atcacgaata atataagagg cctgtgcttc ttctacagta ccagacatgc
     4021 tgtgtaggtg gtaaaagcct tgatagccgt ccgttttttc aggacgatcg tcaactggta
     4081 attgactatg gaaatccatt gctagctgca gggcattaat catctgattt ttagctgtac
     4141 cagggtgaac attgcgacct aacaccttga gctctagggc tgctgcgcta aaggtttcat
     4201 attgtagctc gccaagcgga cctccatcaa tagtataggc aaagtcaaca tcaaaagcat
     4261 taacatcaaa cttatctgca ccaacaccaa tttcttcatc aggtccaaag gcaaccttaa
     4321 tgtcgcaatg ctcaatctga gggttggcaa caagaaactc aatagccgtc atgatttctg
     4381 caattccaga tttatcgtca gctcctaaaa gggttgtgcc atcagttgta atcagggtct
     4441 gtcccaaata ttggttgaga tttggaaaat cctctgggca taaagaatag cctgactgac
     4501 caagcttaat ctccccaccc tggtagctct caataatctg aggggctact ccttctgcat
     4561 taaaatcagc agtatccata tgcgcaataa aaccaatttt ccgagtcaat ttgctgctgt
     4621 tagctggtaa gcttccaatg aggtagccat tagctggatt gtaatgaatg tcctgtaggc
     4681 caatagcttc catctctggc tttagcactg ttagagcaaa gtcagcttga ctcttggtgc
     4741 ttggagttgt agtgcttgct ggattgctcc ttgtgttgat ttttacatag ttcagaaatc
     4801 gttctaataa agtttcgtat gtcatagatc acctcgataa gttttcgtta ctattatagc
     4861 ataaaaggac ctaaaatact tgcctaagct cagtttttta cagtgcttta tctgttctgt
     4921 tacagttgcg ttctcataaa aagacagctg ccaagaaagc tcttgacagc cttgattatt
     4981 catcagccca tgccttaatc ctcataacca tttgggtgct tgctttgcca tctccaagta
     5041 tctgtacaca tcctttctaa gccgtactct gcagtccagt taagctcttt tttagccttg
     5101 ctagcatcag catagcaggc tgcgatgtct ccttgacgcc ttggtaatat cttgtaagga
     5161 atagacctgc caaccacctg agaaaaggct tcgataatat ctagcacaga atagcctgta
     5221 cctgttccta aattataaat agataggctt ggctcttcag caaactttgc aagcgcagcg
     5281 acgtgtcctt tagccagatc aacaacatgg atataatctc taacgccagt gccgtccttg
     5341 gtctcataat catcaccaaa aacgccaaca caatccagct taccaacagc tacctgagaa
     5401 acataaggta ataggttgtt aggtatgccc ttaggatcct ctcctaaatc accagactca
     5461 tgagctccga taggattaaa ataccttaac aatacaatat gccactcatt atctgatgca
     5521 tagaggtcct tgaaaatctc ctctagcatc agctttgtcc taccgtaagg attggtcact
     5581 gatagtggaa aggtttctaa aataggaacg gtatgcggat ctccataaac cgttgctgag
     5641 gagctaaaaa tgatcttttt acaattaaag gctgtcatta cctttagtag ggtcaatgtg
     5701 ccagagatat tattgtcgta gtaatcaagt ggaatcctgc ttgactctcc aacagctttt
     5761 agccctgcaa agtgaatgac actcacaata ggatgcttac tgaaaatatc tgttagcagc
     5821 tgttgatcgc gaatatctcc ctgataaaag gtcacttctc ttccagctat cgaggcaaca
     5881 gcagctaggc ttttaggatt tgaattgcac aaattatcaa ccacaacaac gtcatagcca
     5941 gcagctagca gttcaacaca ggtgtgtgac ccgatatagc ctgcaccacc agtaactaaa
     6001 atacttccta acattgatta tatacctgac tttctaataa ttactaatat tataactgat
     6061 tactcccaaa aagtatatct atcatttcat tttaaagaaa tcaggatagg cattaatgta
     6121 gcccttgcct tcaataagat catattctaa cagctttaag tcagaggcca cctgcttttg
     6181 agcagcagtt agctggctgt catcgctatt tctggtatcc aagacatctg tcaaaagagc
     6241 gtagtaagga gacaccttgg aatccgtatg ctctagcaat aaagaggtaa aatcactgga
     6301 attaacacga ggtctagcca atttgttggt ctgatgattg ctccagatga aataatctgt
     6361 taaatatttg acctcctcat cattcttaaa gacctgatct ggataaaagc caggtaaatg
     6421 atcaccataa aacacaactg taataggctt gtcaaccttt tccagtgctg ataaaaaggc
     6481 ctttgttgac ttgtcggtaa tgcttaataa attcacataa ctttgcaggc tatccgtctc
     6541 agactggtcc agtcctgcta ggctaacatc aacatctctt agctctgtgt accaagggcc
     6601 atgattttgc atggtaatca ctgaaaagaa ttgacttctt ttggggttaa gctggtctaa
     6661 aatattgtca taggttgact catcactata gcttgagctc attcgtatca agtgctttgg
     6721 cttgtcagct gaatcctctg tggcaatgaa ggtatcaaat cccaatttgt tgtaaacgat
     6781 ttttcgagag taattgttgg cgctcgcaag gtgcaaaaca atcctatcct taggcgaaaa
     6841 ggcattacta atggcaggcg aaaacttcaa cttaggaaag acatcagaat acaaaatcga
     6901 aactgttgga ttgaggttat attttggtag gccaaatagg ctttgaaact ccatattagc
     6961 tgtaccgccg ccatagccat cagaggtcat taggccactc gttgtggttt ccatgatatg
     7021 atggatctct gcaataggat ccttggccaa ttgaacccca gaaatcctag ctgggtcagc
     7081 aaagctctca ctcagtatat aaatcactgt ttgatcagaa atacgctgat gcctttgctt
     7141 attgatatca gcagctctag cttgatattt ctgataaatc ttttgcatag cgctcttgct
     7201 atagcctgaa ggctgattaa tggtgctggt ggtaacctgc ttgaaccaaa caaagctcaa
     7261 ggattgaaac cttgcattgg ttgtaagacc ataccagtca atatcaaaga cattgtagac
     7321 tgatgacaga actggaatac cttttttgat ttcaccatct ttattttggc taaatacaaa
     7381 aaggatagag gcaaatacca aaaggataga gcctattgac atcagtctaa gataaagcgc
     7441 tgataggatc ttttctctaa agtatctttt atacaaaaca tagatcagca gacccgacaa
     7501 gactagtatc aaaataatac taatgatttg agtcagacta atgtaattca agaaaaactt
     7561 aatctctttg atccatttca aatctgaaaa caataaaggc tcacttcgct gcttgtattt
     7621 ttcaatatta acaatactga ttaaagctcc gatcaccgta ttgacaaata aagcaatgat
     7681 atagttgtta atgagcaaaa acaccagcac aaaaaagagg gtcaagacaa gcacctgaaa
     7741 cagggttgca cctggaataa tcactgcccc atgaaaatca ccatatgctg tgatcccagc
     7801 ctgaataaag taattaaaga tgatccctaa aaataagctg gtcactagag ctaatctaag
     7861 accccatcgc ttgctcaaaa cctcgataaa ggctgtgacg atgaggtaat aaaccacaaa
     7921 cgtcagcata taagagcaaa agctatactt aaagagattc aggctaacaa ggtttgactg
     7981 actatctaaa ggccaataat cattttgctt aatcacagtc ttaaataaag agctgttcag
     8041 cgttaagact gaaaaagcct gactaagtaa aatgacttgg attcctctgt ttgattggta
     8101 gtccttctta aacaggtatt tttttaagag aacccctaaa ataagcaggc tgactaaagc
     8161 tgccagactg agtagcattt cctgaatcgt acgattactg atggtaaacc tgctgttgtt
     8221 tttattgatg gctaaggtga tatagctatt agcaacagca tagtagctac tgacagctac
     8281 agaaacaata agcagctttg aggaagcatg cttgatcagc aaacatgcca ttccagctat
     8341 taacactaag acaagccacg aaccataagc tcccttattt aacgtgtttt tgcttaccgc
     8401 aaaaatagat aaataaagag atgaaaggct aaacaatatc atatcaagca tttctagatc
     8461 aactaactgg cgagcttttg aaattatctt cgttattata atggtcacac cctttcctaa
     8521 ctgctaaaag ctagacatta ctctctgact cagaagcgat tacctctgtt actaattgac
     8581 gaacagtgac ctcccaggta aagcctgaaa gcacctgctg atgaatggct tcttgcaggt
     8641 cacaccgttt ttctttgtgc tcaatcaaat gatccaactg ccttttaata tcagagactg
     8701 tatcatcaat gatgattccc tgtgacgggc tcgttatcac ttccttgaca ccacctctat
     8761 ctgttgctaa tacagcacat ttcaacatac ctgcctctaa tacagctgtc ggaagccctt
     8821 cagcatagat ggacggatta acaaaaatat cagattgaga cagcaaagac atggtctcag
     8881 caaaattcag cttgcctgta aagatgatgg actgatcctc tttatagcta tctcttagtg
     8941 aagcaagcaa gggaccatct ccagcaacca ccaagacagc cctgtcctta tatgtcagct
     9001 gctcaaaagc ctccagcagc aaaagaatcc ccttttcctt gatcactcga cctgcaaagg
     9061 taataatgac cttatcctgc aaagctggta aataagcctt tgacttaaag acctcataaa
     9121 gatcagaatc aactgaattg tagatgacgc ctttggcttt tattccaaag gtcttgagcc
     9181 atgccatact gcgcttagac accgcataaa agtcgggctg ataggctttg acaaaaaagg
     9241 taattacatg ctcatagact ttagcaaaca agtctagtag ctggtgacct ttaacatttt
     9301 cgcccacctg aacatagcca ccaccatgct cgatcacaat actagggatg gcttttcttt
     9361 tggctagctt caagcccatg aggcttgtca aataaaatcg tgtattgcag atcacaaagt
     9421 caatacgttc ttccatcagc tccgccagca tgctatgata cagatcattc ttatctaaaa
     9481 tcggatagcg ctgcttaaat agctgctttg aaggaaatcg gtaataagta atggcttgat
     9541 ctctttcaat agggctcagc tggtggctgt tgctggttac aatgatgata cggtagccta
     9601 ggctcactaa ttgttgcgct attttttctg tataccgctc tactcctcct agatgagggc
     9661 ttgtaaagcc gctaaaaatg gctattgttt tcaaagcttt tcccttctta tgtataatat
     9721 tgcagcattg ttcgagtaat catacctagg atcaatagca acgagccaat aagaacctgt
     9781 ttattactta ataggccttg ggccttttca aggtatttgt tattagaggc cagcaagacc
     9841 aacactaaag ggatcacacc caaaaagtac ctatcttgaa cccctagcac attaaggtct
     9901 ccaactggcg taaaggtcaa ataaaggcta aaggtaatac cgcctattat tcctaaagac
     9961 atcaatccca taccaaagcg agataaggtc ggcagctgaa gcttgttggc attagtgatg
    10021 acaacagcaa aataataaac catactaatt ggcatgagct ctaccatacc gtatgataaa
    10081 gggccaaaca tgtaaatccc tgaaggatta aggatatgag ccaacgtgtg tcttagcagc
    10141 ataaagccat atactatagg gttccttaac acagtcagta gctgctcttt agcattgacc
    10201 ttctggagaa agtcagccat atccacctga ggtgacttga tttgaccata tacctttaac
    10261 caaaaaacag tcacaaccag caccgtcaga attgacaaca gctttagcag aaacgtgcga
    10321 gaggcttttg ctccaaattg acgtgaaggg ataaaaagca gcaacaaaat caataaaata
    10381 taaggcagct tagtaaaggt aatgattgag cacagcaggg tataccaaaa gagcttggat
    10441 aagggaatct tttcagttgt agccatctga acaaataaag aaatcgtcag aataatcaat
    10501 ccaatagaga cacaatcctg attataagaa ccagcaagat agatattcat cggaaggaga
    10561 cttcctacag caagcagctg cttgcctgct gtcagcaatc gtaaggcaac aaaaaccaag
    10621 atggcatagg caagaacatt acaaagccta cctaaaaggt aagataagcc catggtcaag
    10681 cctaagctcc ttccaataaa taagcctatt acctgtggta tgtaggcaaa gttataatag
    10741 ccatttgttg agcgaatttc cttaaatgaa atagcctcat ctgtatggtc tctgctccac
    10801 agctgaaagc gtaagggctt gccattgttg tggtccataa gattaatgtc atcagtcacc
    10861 agcagctttg agtcatcatt ggttaaatta agatttccct cagataagta taaggctctt
    10921 gcaaagtgaa ccctctcatc aggaatatca ttgatcggtg agatgaaggc agagacagaa
    10981 cccataacca caataataag cactgtcgca tattccatat ttgaaggtaa aaagataatc
    11041 aaaagcgcag caattgcaac taatattgct aaaaatttaa tgggtaaatc cgttgattgc
    11101 gtatataaaa gcagcaacac aagaaaggca ccaagtaaaa caagcaaagc cttactcgcc
    11161 ttttgcaatt tgtcaaataa ggtatctaac atatcctatt tccttttttc cataatgtac
    11221 aagccatatg acaatagcag ccaaatcatc attgaaatta taaaaccata ggtaactcca
    11281 atcaccccaa agcttctagc caaagaacca gtgatggcta gtgaggagat aaaggataca
    11341 acataaggta tcacaagcaa gtgctgcttt ctgataatgg taatcaaatt atcaatataa
    11401 gtggcaaagg tgctgataat ccctccaaaa ataagaagca taaaatcaag ctggtaatgc
    11461 cttaaatcaa taccataaac aagcgatagc accggcagcc ccacaaaata gctagcaagc
    11521 aagatagcta ggcttgctaa tagcagcact agactgagac gacgctctaa ttgtgcaaag
    11581 ctcttcttgt cctcttttga atggtaaatg gccagctgag tgatcatagg ccttaaaaac
    11641 aagaaaatca ggttaatcat aaaaataggc ataaacaaaa tattaaattc tgtttgaaca
    11701 ccggctggga tcagctgctt tgagtaaagc tgctccaaaa caaacttggg ctggttgtag
    11761 atataaatga gtaaaaaacc atttaaaaag aggggaaagc tctccttcaa tagccctaag
    11821 atgctttgag catcaatacg acgctcaagg ctcgtaaagg aaactgaagg ggttatgtca
    11881 aatagcacaa tacaagccac tgaaataaga catatcacga tcaaagacag gactagctgc
    11941 ttggtcagaa ccagacagag cgtaaagcca agaatcacca gcatatttcg ataaaacaag
    12001 gatttgccgg caatatctaa gcgctctctt tgttgaaaca ttccttgaaa cacatcagaa
    12061 atggcatctg tgcaacgata caagcaaatc aaccaaatca ctagcccctt aaacccacta
    12121 tagctcccca aataaatata gagcactgaa atggctatca tcaagaaaca ggtgactagt
    12181 cttgtataaa aatagtcttt gaagcggtac ttgtgtaata tatccgttga ttggaaattt
    12241 ctaatctgaa ataagccaat agtaatcagc tgatttccaa tagcataggc aaagctaaag
    12301 gtatctgaag ctgatttaga taagacccga gacacaatca tcagtaaaat cactgatatt
    12361 agtgctgtcg agctggttcc caacacattc caaataaaaa tcgactgatc cgattgaatc
    12421 ctactgctgg ttttcatctt cttcctgctt ttccttctca ttaagggcta aatactgaat
    12481 cattttttta agcttaatct ctgtccgaga caatttttga gtgataaaaa attggttgat
    12541 gatgagtaaa aaaatgattg atagaaaaac aaaatttgcc ggcgattcaa agcctagcag
    12601 ccttgaaaaa taaaccgcag catttggaaa cagtgacagc aaaagcacta ttaaagagaa
    12661 aaagagccaa aaaaagctat cttcaattaa aattttggat ctgcgaatgc tatctagtat
    12721 aaacatggct gtcaataatg caacaatgat caaaatcagc tgtaacccaa taaacatcct
    12781 cttacctctt tctaaagttt tgaattaaaa taatcgaaat aaacatgtga accatgtatt
    12841 taatagatct agaaagagtg aggtagcttt gaccagccag cctatcattc atttgcacct
    12901 gaacctcact caccctatag ccttgtcgaa taagataaga gatcgtatca ggctctggag
    12961 tatagttaat attagttgca aaaatcctga tcagctcctg attaaacatt ctcataccag
    13021 aggtcggatc ggtaatacgc tttcctgtgg ttagcttgat aaaaaagcta ataaggctat
    13081 tgcctatcat tctcaaggat ctattctttt cagcactgac aaaccttgat ccaatgacac
    13141 aatcagcacc agcattaatt gaatcgctca aagcctcaat atactctggc aagtgttgac
    13201 catctgcatc gaactggagt gctttagcat atcccttttt aaaggcatat ttaaagcccg
    13261 tctgaatagc accagataag ccaagatttt ccggcaaatc aatgatattg taatggttat
    13321 gatgacagat ctctgatgtc cgatccgaag agccatcatt gataatcaca taatcatatt
    13381 gaggaaaatg tcttttgata ttttccacta ctttttcaat cgactcctct tcgttatatg
    13441 ctggaatcat taccaataag tcttttttca tatcgtcaaa tattctctct attcattcgt
    13501 ctaaacgcgt ctttttagca atcgctttat gatataacgg atagccttag ctggcccaat
    13561 cacaatatat tttaaggctc cttttatacc tcccatatag tcaaaatcga cataggtatg
    13621 tggcacactg ccttcacgca ggtttaagag cttattatca ataaatggtg tcaatagctt
    13681 ttcatttctt gaaattctaa aatcatagtg tctgtcccaa gcaatataaa ttaagagacg
    13741 ttcaatggca tgcaggatcg aattttgaga cagaggctct gctggaatat cagcctcact
    13801 taggtctaag tcaaacaagg gctttaaggc atcgtattta aaccaaacaa aggtgccata
    13861 gctcatgaca aaggtatcca tcgtctgaaa atcaatgcgt tttgtaagcc ccattgcctg
    13921 ccaaagctga ttcatttcag gggcaataag gtgctcattc caagcgtcaa caattttatt
    13981 aaaacggaaa aaacttggaa tatctgctat cacaataccg atagcatcag cagccagtgc
    14041 tgttaggatt tgatccgccg gcttcaccat catatcaatc aattcagtgc gccaggattg
    14101 gcccgcccaa aaatctgctt cctttgattt tttggtatga aaatgcccaa tataatcata
    14161 ttgagacaat cgttccttta aggtcagcat tggcaagaca tctcgaccga tatttcctgt
    14221 caccaatatg tcagcacttg ccccgctttc tcgtagaatt tctttaatct cagccttttt
    14281 agccttgcta tcggtcgtta tgagcaagtc ataatcaaaa tgaaaatgac taaatgcttc
    14341 taaaaactct gacaataaat caacataaaa aacatgaaga tgaacagcaa ttttcttgct
    14401 ttgatcaatg cttatcggct gctctggcag gtatttatgt gccagaagat acttagcatc
    14461 tggtggatgg acctgcgaca tatgatccac aatcaagctg gcagggtatg tcgttttttg
    14521 gtcaataaaa tccaaaaggt aaggagcaat gtgctggtta gcgtcaatag ccttaacctt
    14581 gataaagggc acatggtgct ttaagatggc tgtcggattg taataagaga aatccgcatg
    14641 cagcatagag gacgagtcct ccttggtcgt atcaaatacc gtcttgtatc gaaagccagc
    14701 ctccacaaag acagtggtta ttctggtttc ataattgtgg atcacatctt gaacgtctgt
    14761 tagctcaacg atattttccc aaaactgcct aaattcctta ctatgaacga gggatttttt
    14821 gaagctgata aaatagctct gaatatgctc tttaaaggcc ttggtcgctc gattgttggt
    14881 catgccccag aaatcaactg cttcatctgc ttcatatttg agataataag gcttcatatc
    14941 ccaaagcgga ccaaagcagg tatcgttcat aatcgtgatt gagtcaaagt caacaaggtg
    15001 ctcacagcct aaggccttca taccatcatg ccaagctgca aaatcatagc ctttattgtg
    15061 tcgttgaata aactgatcca tcaaatgccg ctgttcaagc tgctcaaggt cctcttgatg
    15121 gatatcacta tttgaaataa agacaatctt tgaaaacaag gctctcatct gttcgagctg
    15181 gtaataaaca tgatcgctta ccttatgata tttattgaaa tgcacataca ataatagacg
    15241 cttcattttt tcctcctaaa aagctcaagc agctttgata ggtacctcca acgacgtgag
    15301 gtaaccacac aattgtattg atgggttagc gcttcaacct cttgcctttg atgatcaagc
    15361 tgctgctgta gctgatctat cttctctgcc tgtagagcct cctgatctgc aagcgtctgt
    15421 cgtaattgat gaatggtatg acttaattga tgaatccgaa tttcattttt agcgtcctgc
    15481 tttagtaatg cttttgcaat agcttccata ttggctgtag ggtatttaga caaataggac
    15541 agctgggtct ccaacaagcc ttgaatacgg cccagcattt tttcctctgc tgccggcctt
    15601 gaatctgaat tatccgtcat tcgataaaca gtggtcgaat ccttcaaata ggctagagag
    15661 gttgactgaa acagctctaa ttgtatgtca aaagtgtcgt ctgacgtctc caaatcaatg
    15721 cgttgattaa ctgccctcat cagatcagcc tccaccagcc aggttgatga catggtcatt
    15781 ccttttaaag caagcatttt ctcgtaggtg tctgttaagg gagtaaagcc actttcaaag
    15841 gcattgctct gaataagctt gccgtcagta tctacaaaat caaagtcagt attagaccat
    15901 tttgaatctg gtgagctatc cagcaaatca acctgctttt gtagcttgag agtatcagtc
    15961 caatagtcat caccatcaca tctggcaata tactgtccct ttgcctccaa acaagccttg
    16021 acccaggttc ttgcaatccc aagatttacc tcattaacga tgagtcgtat acgatctgga
    16081 aagctggctt gatagtccat gaggatctgt ctggaatagt ctgttgaagc gtcgtcaatg
    16141 acaataattt caacatcaaa gctggtctgt tgggctaaaa agctgtctaa ggcctctgaa
    16201 atccaaggcc ccttattata attggtgcaa ataatagaaa cttttttcat aggatgcttt
    16261 ctaatgacaa ttattgatta atgagccagc taccatttct ttgatataag ccactggcag
    16321 agtccaaagc agacaggtca tctggagcaa tatcgtttcg ttgaagcacg actaatgggg
    16381 aatgattagc tgttaaaaag agcagcattt gcccgttttg atcgcgaaca gtcacctcaa
    16441 gctttaattt gatatcattt aggtgtgaga gctgacactg gtaggatatg ttcttatgac
    16501 caggaccact tgtcggttga tcctgtgaat tgtcattata tacccaaata ttgcggtcaa
    16561 tatcagtcaa cgaaaaggca acataggtag gctcgtcctt taagacatga taggaaatct
    16621 caaaggaaat gggctcatct ggactaaggc ttggcttaga ggtcaacctc acctctaact
    16681 ggcttgccaa atcagacaca ggctcagcag cagctccttg ctcagcattt ttcaattcag
    16741 tattatcaac actgtattgg ttagcgacat caaagggttc gccgtaagcc ttgacaaggc
    16801 cattttcgat gaggactgcg cgattgcagt attttttgac agcccccata tcatgggtca
    16861 ctagtatagt agtcttgccg ctctccttgc gctccatgaa gtagtcattg cattttcgtt
    16921 gaaaggcctc atcaccaaca gctaacacct catcaagaat cagcacatct ccctgtgcct
    16981 tgatagcgac agaaaaagca agacgaacct gcatgcctga ggaataattt tttaattttt
    17041 gattcatgaa atcatgcagc tcagcaaagt caacgatatc atcatacata tcatcaacct
    17101 cttctgtggt aaagcccagc attgcgccat tcatgtagac attttcacgc ccagtcaact
    17161 caggattaaa gccaacacca agctcgatga aggacaccat tttcccctca actgtgacct
    17221 gtcctttttc tggaacataa atttgagaaa taatttttaa taaggttgat tttccagagc
    17281 catttcgtcc aacgatgcca aaaaaatccc ccttatacac gtcaaagcta atatccctta
    17341 gcacatgctg ctcggtatag cccttaatgc ctttaaaacg gttaacaaga gcagtacgaa
    17401 agctcttggt tgcctctgtt ggcagcttaa aggacttact gacatgatca actgttactg
    17461 caatttcttt attagccatt agataatctc cgcaaacttc ttagcatttt tattaaacac
    17521 tgctacccca agtgctaata ggacaaatgg aatgaggtaa ggaatgatga tatagcacca
    17581 atttgtcgac atttgccaaa tggtcacatt agctctgtca atcagcagat accgcaaatc
    17641 ttgaataatc tgtgctaaag gattaagcat caaaatcttg gcagcaagag ggtgtcggtc
    17701 aaacacaaag gtaatcgggt agatgatggg agtcacatac atacctgcct gcaatagaac
    17761 ctcccaaacc tgagccaaat cacgataata aacaaagacg gtagaaagca tcaaggccac
    17821 accaactgta agaacagcca gctcaacaaa gagtggtaag gccagataag cgtgaggaga
    17881 taaagtaact ccattgatag ctgcaaaaac caaaaccact aataggttga ttgaaaagtt
    17941 aatcaatgct cctaaaactg ctgaaaaaac gatagtatgc tttgaaaaat tcaattttct
    18001 aagcaggtct cctcgcgata caatagagac cattcccata ctggttgctt ctgagaaaaa
    18061 ggaccaaatc acattggcaa gtaaaagagc aaccggaaaa tgaggaacgt caccaccagt
    18121 tcgcaaaaac ctgataaaca ccaaatacat gatggtaaac atcatcaaag gctttaagat
    18181 agaccacaaa taaccaatag cactgccctg ataccttagt ttaaagtctg ttttaacaag
    18241 ctctttcaaa agaatacgat tctttttact caataattcc attattcttt tctcctatag
    18301 ccaaatttgg tcatgatcaa tgccataaaa acaagggtat gaaaggcacg atttttccga
    18361 aagccatacg ctttgaaatc agacagacgc tgatagaaag gcctatccaa aagccctacg
    18421 taagcctcaa tcaatcttct gtcagccgga tttagctgca agtctagcaa ttgccttgct
    18481 tgatgttgac tagaaacaat aagccaccaa tacttctcta tgagcttatg gggcttacgc
    18541 cactgcttca gtcgcttaga ccaggttctt gcccctaaaa cattagcatc atgctgacga
    18601 tagagctctg ttgccacatc tagatacaca agctctccct gcgctgctgc aatcaaggct
    18661 aaataccaat catgcatcac cacatgctca cagctcaccc actgctctgc cagcgcgtga
    18721 ttaatcatca tagtgccgcc tgtgactgtg ttttcagtca actcctggac tagctgagta
    18781 ttagcatgat gtgattgtgt ttggatcata ctctcatgac gtacttctaa gtcttgattg
    18841 accaccttta ggtctgtgta gactagtaag ggctcgctta tcttgtgctt ttgcgcttct
    18901 gccagagtaa gctctaattt attgtctaac cacacatcgt cttggtcact gaaaaaataa
    18961 atatctgcct tttcatatgt taaaagggtg tgaaagcttc gaatcacacc gaggttttcc
    19021 tgcacatcag cattaatcaa gcaaattctc ggatcctttt tagcaaaagc ctgaatgatg
    19081 gcaagcgttt tatcagtaga gccatcatct ctgactaata aggtccaatc ctgcaccgtc
    19141 tgcctttgaa tgctttgtat ttgctctgct aaaaaccgcg ccccgttgta ggtagacatt
    19201 aaaatattaa tcttcatcta aaaataaggc ctcatactct cctacaattt tctcccaggt
    19261 atattctttg gcaatgattt gcttagctct ttctcccaaa tcagcaaacg attccttttg
    19321 atcaaccctg ttaatcagtc cagtaaggct gcccttttct tttgtccaat aaagggctgc
    19381 tgttttagca actgattgat taaaggtcac tcccaaaacc aaattaagct gggtatgggc
    19441 tagggcctcc aaaagacctg gattggtacc tccaacctca tgcccatgaa tataagcaaa
    19501 agcatgctca cgaatataag ctaaaagctg cttatcatac tgtgttccaa caaattttac
    19561 acgcgcgtcc ttatcacagc cagttgcact aaccagccgc tcaaaataag gatttttgtc
    19621 atggttgcaa ataataacca aatcccgctg agtagatgat gccataaact ctctaatggc
    19681 tgtttcatag ttgttttcag gaacaaagcg ccccaaaatc aaatagtatt ggttttctgt
    19741 tatctcaaat gtttgaaagt aagttctgac tttttcatct gatgtagaca aacaagaccg
    19801 ccctatttct gtcccatagg caataaaagt cgtttttgcc caaggataag actttttgat
    19861 gtaggcttca atgccaatat tatctgagat gaccaaatca gcatgctttg tcatttgctt
    19921 ttcggcgtat ttcaggtatt gctgaacagg cttagaccat tttgaacgct tccattccag
    19981 cccatcagga ttaatcaaca aacgcccacc acgctggtga atctgctttg caaagggggc
    20041 aataaagcct ccaatggtat tgcctagaac ataaaaaata ggcttttgaa tatgatacct
    20101 atcaatataa gctaaagcgt gactaatagc catcatatca taagcaatca ctctagctgg
    20161 accgagctta ggaggattga tataaaaaca atctgctccc ttgtacacaa aatgctcctt
    20221 gtgcttgcta tcgctcaagc aggcaatatg ataggtaatg cttttgttgg tctgattagt
    20281 gactaattct tcaacaaagg tctcaaaacc accatacttt gctggtaaac cgcgacttcc
    20341 gatgatgaaa acatcctgca tagcacactg ccccattcta aaatataatt agtagtatta
    20401 taccatataa acaggtctta tgcgacataa aatccatgaa aagagagcca atctcctaga
    20461 tcagctcttt agtgctatcg cttattcatt gctgttgctt gtaaaaagcc tccagggctt
    20521 cttgccaggt aggaatcaca aaaccagttg ccttagcctt atcaagattc atggttgagt
    20581 taaagggtct tttggcttta gcaggaaaag ccgatgaatc cacaggcaca acctcgacag
    20641 ctgtctcttt taagatttct ctagcaaaat cataccaagt ggtgtcttct ttagcatcat
    20701 ttgacaaatg ataatagcca taaggcttgc gattgtctgc tagatgacac ataaactcag
    20761 ccaaggtcct cgtccaggtt ggacgcccat gctgatcatt gacgactgtc aagcgagagt
    20821 gggtcttagc aaggttttgc atggtaaaca caaaattctt gccataatga ccaaacaccc
    20881 atgcggtacg aataatgtaa aattgcttgg tatatcgctc aacagccagc tcacctaagc
    20941 gcttagcacg accgtatgct gtttgaggat caggagtatc tgtttctagc cattcctgac
    21001 cagctggctt ttgaccatca aaaacgtaat ccgttgaaat ataaaccaag gtcgccccgt
    21061 agcgctcaca agccttggca atatgctcag taccagctac attgatagct tcattcagtg
    21121 cttttccttc ttcttcagca gcatcaactg ctgtgtaggc tgcacagtga tacactaagc
    21181 taggcttgac ctgagcaaaa acctcctcta ctttagtcgc gttggtaata tccatttcag
    21241 caacatcaac agcaacataa tcgacgcttc gttcgtctaa aagataacga agctctgttc
    21301 ctaattgacc attacttcct gtaattaaaa tcatcttttc tcctttgtaa aggtcttatt
    21361 tctttgagct aatcacgcag ctcactccca tctaatccta agagaggctt ttttgatcag
    21421 ctgaccctag caagaccttt gttgtggtat cgtatcagcc ttgcttttta tctagctacc
    21481 gaatacctag ggcaattctc gcatagcggc tcatcttttc aacgctccaa acagggtacc
    21541 agaccaactt tacctcaacc ttggtcacct ctggaacatc tctcatcgca tcatgaatat
    21601 gatcagtcaa caaatccgcc aaaggacagc ccattgtggt caaggtcatg tcaatctcgg
    21661 tatgaccatt gtcatcaaaa cgaatctcat agaccaagcc tagattcaca atatcaatac
    21721 ctagctccgg atcaataacc gttcccaaag cttcaagaat ccgatccttg atagctgcaa
    21781 cctgctcttc tgtgtatttt aatgtttcag tcatagctat tcctttcact tttttcgaag
    21841 acctgatatg atgccaagtc aaaaaccagc ccaaagacca gcgcattcag catacctatg
    21901 atgccctaag ctgactaaca ttgatagcct ctttttagtc acccttacat taacactagt
    21961 ctttagctac tggctagcaa aggtaatctc ataaaccagt aactaggctt ggagtcgttg
    22021 accataggcc actcaccgtc aaggagagat aacgcatttc gggctcgtct cctattttta
    22081 gctcgccgtt aaaaaggtcc accggacctt tttaatcctc aatgaagtct ctgagctgct
    22141 tgctgcggct tgggtggcgg agcttacgca aagccttagc ctcaatttga cgaatccgtt
    22201 cacgagtgac attgaagacc ttcccaacgt cctctaatgt acgcattttc ccatcatcaa
    22261 gcccaaagcg caggcgaaga acattttcct cacgatctgt cagcgtatca agcacttcgt
    22321 ctaattgctc acgaagaacc acacgagttg tgtaatcaac aggattttca atcacttcat
    22381 cttcaataaa atcacctaaa tgactgtcat cctcttcacc gattggtgtt tcaagagaca
    22441 ctggctcctg agcgattttc agaatttcac gcaccttatc aggggtcatc tccatacgct
    22501 ctgcgatctg ctctggagta ggatcctgcc ccaattcttg aaggaggttg cgctgctcac
    22561 gcactagttt attaatggtt tccaccatat gcacaggaat ccgaatggta cgtgcctgat
    22621 ctgcaatagc acgagtaatg gcctgacgaa tccaccaggt cgcataggtc gaaaacttga
    22681 agcccttaga ataatcaaac ttgtcaacag ccttcattaa gcccatgtta ccttcttgaa
    22741 tcaaatcaag aaattgcatg ccacgcccta cataacgctt tgcaatcgac accaccaaac
    22801 gcagattggc ctcagcaaga cgctgcttag cctccatatc accagcggct actgcaaccg
    22861 ctaaaacctt ttcctcatca cttgtcagca gcggcaccac accgatctcc ttgagataca
    22921 tgcgcacagg atcgttgacc ttggctgaat tacttccgat aagctcctcg tctgtcagct
    22981 cctctggctt aggctcttca acgacgtatt tagatgaggg atttccttcc ttatctgtaa
    23041 tggaaatgcc accatctgtc aaacgctcaa gcaaatcatc aatttggtca gcatctaagg
    23101 taaatggaat cacgagtttt tctgtgacct catcatcagt agctgttcct tcctttttat
    23161 gatgacgaat aaactccgca atttgaacgt taaaggttgt aatttctttt tcttttgcca
    23221 tattttcctc tattccattt ttcttttttc agcaatgaaa cgctctaaag cctctagagc
    23281 catctggtgg tcacccttac tgctagattc cctaatctgc tttccttgcc tatgcagctc
    23341 tctttgcttt agcaatgtca tttgccttga taaaatatcc tcaatctcac cgctagctat
    23401 ctcatcagga agattttcct ctaaaacccg gtaataggct tggttaacct cttcagacag
    23461 ttgcgatagg tcataggagg taatctgccc tgtggccttt agctgctcat acagcgtctg
    23521 aagggctggt gtatcaaaat aaaaatccgg ccgatgacga aattcattga gcaaatagtc
    23581 gtgatgaagc aggcgatgca ggaggtgact ttctgtttta gccaaggctg tcatgctttt
    23641 gttaatcggt aaggtcacca gagatgcctt tggttgacta gcctgtcctt gttgtaagct
    23701 ttgcctatct tgtagcctta aagcatttac cgattgctcc acctgaaaat aatcaaaatc
    23761 cggcagcaaa tcagccacct tattaatata cgaattttgt gcggtgattg agggtgcttg
    23821 agcaataatc tgtgatatat gctccacata agcaatctgc gattgcaggt tatccatatt
    23881 ttcaggcttc aggtgatcaa tcaaaaactc aacactgcta atgcgcgagt gctggagcaa
    23941 ttctgctaga gcctctggtg aatgctgctg aacaaattca tcgggatcca ttctatttgg
    24001 tattttcacg atctccactt gaaaatctgc cagcagctca agagacttgg caatagcatt
    24061 ttgcccggcg tcgtcaccat cataagtcaa tacaaccttt tgtgtcagct gcttgaggtg
    24121 cctaacatgc tctggcgtca aggctgtccc catagaggca acagtattac catagcctgc
    24181 ccggtaggct gcaataacgt ccataaagcc ttccatcaaa aagacctcat gagtcttagc
    24241 gattatcggc ttggccttat caaggtggta aagctcatag gacttgttaa ataggaccgt
    24301 agcccttgaa tttttatact tggcctgctg cttttctata tcctctcttg cccagatacg
    24361 tcctgaaaaa gcaatcatat tgcccttatc atcacataag ggaaacatga ttcgatgacg
    24421 aaaggcatca taaatagcat ttgattgttc agaaacatga aacaagcctg aggctgttaa
    24481 ttgcgcctca gtatactttt ttgacaaggc ttgataaagg tagtccatct cgttaggcgc
    24541 caagccaatc cgaaaatact ctattagctg atcatcaagc cctctttgat aaagatactc
    24601 cttggctctt tggccaatct ttgtcgtcat caaaaccgca tggtaaaact tagcagcatc
    24661 ttcatgaaga tcaattaaag cctgatgagg gtgctgcttt tgactcaaac tagtctgact
    24721 tggagcaaca gtaactgcca taccagcctt atcagccaca atctgaacac tttctaaaaa
    24781 aggaacctgc cgatattcct caataaactt aaaaacatcc cccgacttac cgcagccaaa
    24841 gcagtgaaag aactgtctat cttcgatgac attaaaagag ggtgtttttt ctttatgaaa
    24901 gggacacaat ccaaggtagt gccgaccagc ccgcgataga tggacaactt ctccaataac
    24961 atcaacaata ttgacattat gcttgatctg agaaatcatc tctttgtcaa tagccaaacc
    25021 gtcacctccc cacaaaaagc ccattgtaaa tttacatttc attataccat tgaaaatgag
    25081 ctttgtaaat tgtaaaagca caatccttca tcatctaaag cccgctacat caagcaataa
    25141 gctatgctaa agtattgacg tctcttatga tcactagctt gactagcagt acagcattaa
    25201 gtagctcatc agtccttgat aagctcttct attagccttt ttgacctatt tgtgctatga
    25261 taagattatc tgaaaaaagg ggagtcaatc atgctcaaag aattaaaagc atttttattt
    25321 agagggaata ttatcgacct agcagttgcg gtgattgttg ggagcgcctt tagcgctatt
    25381 gtcacatcat ttgtcaacga cattatcaca ccgctgatcc taaacccagc cttgaaagct
    25441 gcaaatgtgg aaaacattgc tcagctcgcc tggaatggca tcaaatatgg cagctttctc
    25501 agtgctatta tcaacttttt aattgttggt accagccttt tctttgtggt taaggtcgct
    25561 caaaaagcaa tgcctaaaaa gggagaggaa gagcccgcta agcccaaaac accaactcag
    25621 gaagaattat tacttgacat acgtgatttg ttagccaaaa aataactcaa agctcttaca
    25681 gcagctggac ctgtccggct gctttttgat atacaagcac agagcactta gcgatcaaaa
    25741 gataatagaa ccggctctat ttgctgtttt agcatatcat tgctattttt atcagcagca
    25801 agctaaggta aaaaaagaca aactagtatc ctcatactgg tttgccttca aactaaggca
    25861 gcctacaaag ggccgccttt tttatgatga ttagaatttt ttacgtttgc gagctgcttc
    25921 tgatttgcgt ttacgcttta cagaaggttt ttcgtagaat tcacgcttgc gtgattcttg
    25981 aagagtacca gctttagtaa cagaacgttt gaaacgacga agagcatcat caagcgattc
    26041 attcttacgt actactgttt ttgacatatg tttcacctcc tcaagatatt gtaacatttt
    26101 cacgttctag cttatcttac atgatttttc ggaaaaagtc aatgatcttt tcttgatttt
    26161 gaggtcattc ttaaaaaaat accttaaaat ttgctgctgc attaggcatc acttggcaag
    26221 gctattctac tgcatttcct gttaataatg ctgcttcttg aataaaggcc ttgtatttgc
    26281 catccttgtt taattgcttg atcaccttat taatggtttg ccttaggtca tcactcccct
    26341 ttggcatagc tacagcctta gcatctccat cacttgcctg caatttaaat ggtgctaaag
    26401 ccaggtcttt atgttgagct aaaaagcctg cagctactgg tgcttccaaa tcaacagcct
    26461 gcacctgccc agatttcaac tcattaatag cctcacccat cacagttaga gaaacacagt
    26521 tggctttatt aagctgctcc ttgactaggc cctcctcgat gctgcctttt tgaacagcca
    26581 cctttttgcc aactaagcta tccttattag cataatgctt ggcatctgac gctttcacca
    26641 aaatagcatt ttcagtttca tagtaagcct cagaaaaatc atacactttg gcacgctctt
    26701 tggtgtagga caaaccagaa atcgctatat ccaccttacc agtttgcaga ctggataaga
    26761 cattatcaaa attcatagca gagagttcaa gcttaacccc tagttcatca gcaatggcct
    26821 gtgccagctc aatgtctgct ccgacaatag tatccttgcc gtcaaccaag gccttaaatt
    26881 caaaaggagc atagtcaggg ctaacagcaa ccaccagctt tcccttttcc tggatcctgt
    26941 cttgaaggct cgtcttgtta gcttggccac aagctgccaa agcaaaaaca gataccatag
    27001 caagtgctcc aactaataat cgcttcatgt tcatattata attattcctt ttcttgttga
    27061 tgaatcttat tatattgcat tattattcaa tggtcaagtt tttattgaat atttttcaag
    27121 cactgcgata gtctgcttaa tcctgcctgt agaacctgcg gctgacagca atagccgatt
    27181 ctcacatgat ttgcttgatt aaagcgattt cccggaacga ccaaggtacc gtaatcctcc
    27241 agcagcctca aagcaaaggc ttccatgtcc tcatctatat ctagcctaac aaaggccgtt
    27301 gagacctcat tcggtctatg gtaggaggcc ctggcttcac ctgttatcca gtcctctaag
    27361 atagcaaggt tagtcctgat aatggcttga ttgcgctgca atagcttgtc agcatgcttc
    27421 aaggctagcg aagccaccat atcatcaaaa acacctgcac agatcattgt gtaatctcga
    27481 tataacctaa gctgatcaca gatggtctca gaagcggcta cccagccaac tcgaatgccc
    27541 ggaatcgaaa aggtttttga catgctatta acagtaatcc ccttatcata caaatctgcc
    27601 accgctaaaa gatgatcaga ggtaaaggaa tgataaacct catcacttag caggtaaata
    27661 tcatgctctc tagcaatatt gatgagctcc tctaaataag gcttggtcat ataggcacct
    27721 gttgggttgt tggcattgtt gatcatgatc atttttgtgt tgggacgaat catggcacct
    27781 agctcattaa ggtctggcag ccaagcctgc tcctctctga tctgccaata atcaacctcc
    27841 actccaagag aagctggaat atcatatagc tgctgatagc taggatagtg agcaatcaca
    27901 tgatcacctg cttcaagcag tgcataaata accaaaaaat tggcacctgt tgccccattg
    27961 gtttgcaaga tatttctagc tttctgctgc tgataaagcc ctgccactgc ctgcttaaag
    28021 tcaggagagc cttctatcca gccatagtct aatggctttt gatgcagctg ctggtaaaag
    28081 gcttgaggct gctcctgtgt taagtcaaag agctcctcaa gcgttaatga agcaatagat
    28141 gagccagcaa tatcgtatac agcacgtttt tcatgctgat ttagccactc ttctacacca
    28201 aataccggta gtttcataag atcaccttat ttcttgcgta atatttatta caatatcgca
    28261 taaaaataca attgtcaaat caaaaactat cctttttttg ataagaatca tgtcctatct
    28321 aacagttagt cctgattggt ctcgcatgaa aggctactaa atagagcaaa aatcacataa
    28381 aaagactccc aacccaccaa tcagcgggat taggagcctg atagctcgta tcaattcatt
    28441 gatttcagat cagagtgact atcatcactc tactatgagc caatgactag gctaggcgga
    28501 caacttctag ctgtgatcca cccattaata ccaagtattt ttcgatcctt gcaatcccgt
    28561 aggattggct cagagcctcg gcatataggt ccatttgctg ctgatagcgc tgcttcagct
    28621 cagctgactg ctgatagcga tctgtcttat agtcaaaaag aacaatacga tcctcaaaaa
    28681 gcaggtagcc atcaataata ccacgcacta cgtactgctc ctgacttagg ctgtcttttt
    28741 tcagcatcgc aaaaggagcc tcgcggtgta ggcgctggtg atgctcttgc aggagctgcc
    28801 ccaattcagt tgtcgcaaaa aaagaggtta ccttttcaat gtcaagcctt gccttgacct
    28861 ctgcgtcagc tgagacaagc tgtaaggtct gttcaatatc accagcagta acctgatcag
    28921 acattggaat acgctgcatg agctcatgca ggcttgagcc gacctggcta ggctcaacag
    28981 cctttttctt agaaaaatca ggaagctcaa aggtcttggg cctatgataa ggctgatcta
    29041 tgatatcaac accatcagta tccattagag gctcataaag ggttttaagc tgactggggg
    29101 ttctcaccgt cggcagctca atggccgcct gatagcttgc attgagctct gacaccttat
    29161 ccagcatgtc taaggcacgc gcaatgtcct ctgtttgacg gttatccttg agatcatctg
    29221 cttgcagcag ccctgagggc cttagctgac caacagcttc tggtgttaag tcactgtcat
    29281 caacaaatcg cacatcaata aacaagtcct ccttgctaaa tgttgctgct atcgctagta
    29341 gccagtcttg aaagctcagc aatctttctc gactagctaa ggctaagcgt ccttcggagc
    29401 tattgtcggc tgttttttcc tgtacctttt ccttgctagc cttaccaatg aggtatacct
    29461 ttttttctgc tcgcgtcatg gccacataca agagacgcat ttgctctgat aaggtcgcca
    29521 agcgtagctg ctgcttattg agctggtaag gaagagtttc catcgtaacc ttgagcgacg
    29581 ccaatttttc ttctcttaga agctccttta cattggcgac atatttgata ccgattccct
    29641 catctctatt tagaatgatt ggcgcctgta ggtcagccat cgcaaagcgc ttgtcgcaat
    29701 tcaaaatgaa cacgtaatga aattcaagtc cctttgattt atgaattgtc atgaggttaa
    29761 cagcatgctt aggcctttcg acctcaacat ctgccaaatc attttgcgtc tccagcacct
    29821 tatcaatcat gccaataaag cgtgagagtc ccttgtagcc tgattgctca aattggtcag
    29881 cccgtatagc aagggcgtaa aggtttgcct gagcctgctc tgcctttggc tggcttgcta
    29941 caaagtcaaa gtaaaagcga tcgttaaaaa tcttccaaat cagctcataa agcgaatgaa
    30001 gctttgcaaa ttgacgccag tctctcaagg tcccatcaaa atcagccagc tttgtcatca
    30061 gctcctgacc gatcagctct gggtgctcgc cttgtcctct caagctattg ctaagcttgt
    30121 catagaaggc ttgaggctgc ttttgtgagc tgccttgcag tgagattctt gccagctgat
    30181 cctcatcaaa ggaaaacatt ggcgagcgca ttaaggccac tagggcataa tcattcaaag
    30241 gattgttgat gcttcttagc gtatccagca tgaccatcac ctcaactgat ttgaggtaat
    30301 tttcttggcc accatcagca acgagaggaa tgccatactg attaaagacc tgaaaaatag
    30361 tgtcatttcg tgtgcgtgac gaaacaagca gggtaatatc ttcaaaagca accttctcct
    30421 cgttatagag cctgatgatt tccttagcca ctaagatgac ctcacctgcg gagataccat
    30481 cgttagctaa ggcttcctcg gtgccttctt gaacttgatc ggtgtcatag agcagcaatt
    30541 gggctcgatt gttaggatat ggctgtcttt gtccctcact gcctgctacc agctggtgct
    30601 tgtcatcata ggtaatctct cctaaagact cgtccataag gcggctaaag acagcgttgg
    30661 tgacatttag gacctctgac tgactgcgga aattttcctt tagtaaaatc agcttgccat
    30721 gctcgggatt gctttgataa tccttaaact tttgattgaa gatttgagga tctgcttgcc
    30781 taaagcgata gatggattgc ttgatatccc caaccataaa acgattatgg ccattagaca
    30841 gcagctctaa taggcgctcc tgcatgtgat tgttatcttg gtattcatca accatgacct
    30901 catgataatg accttggtaa gcttggcgaa tatctggagc ctgttgtaaa atctcaatgg
    30961 caaaatgagc tatatctgaa aattcaaagg cattttcttg catttttgca gccaaataag
    31021 cctctgaaaa gctgatcaca aaggcttgca gcacctccaa aagtggtaag ctctcctgtt
    31081 gataagcaag gatagtctcc aagtgcctaa atcttaccag ctgctcctgt agcgatttga
    31141 aaatagggta tttgtgaccg gctacagtta tatcagctcc tgaaggaagt aaagctgtta
    31201 gctcctgtgc tagctgacct agtcgcgctt taccgtaaag gctgtcaaaa tgcaaagccc
    31261 actcatataa gctgtcaatc attttgaggt gcttagtgta tttggcagtt agcttgccag
    31321 ccttggttgt ttgagcgtaa ccctccatgt ctgtgaggtc tcgcagctga tcagcagtgt
    31381 cctgcataca ggctaagaga gcatctacag cttggtctgg aatatctgta aagctggtat
    31441 aggtcttaga ccctcgtaaa aagacctctg ccaaccaact gctaggattg gcagttgatt
    31501 gactgaaggc ataaatgcta tcaacaatct ctctaaaggc tgagctatcc ttacgacgtc
    31561 cagaaaaatt ctgcaccagc tgtataaagg ctttattgtc agtctgcgac atatagtctt
    31621 caaaaacctg acgaaagacc tcgcgcttta aaatgtcctg ctctgcctta tcctgtatga
    31681 tacgaaaatg cggtgaaatc cctaaaacat aaccatgctg gtgaaccaat ttctgagcaa
    31741 aggcatccat cgtaccaata tcagcctgtg ataaagcctg caattggtca ttaaggtagg
    31801 ccttgagctg ataatcctga gtctctgcta tagctgtgtg cagctttttt tcaattctct
    31861 ctattagctc agtagctgct tttacggtaa aggtcgaaat aaataagcaa tcaaccggaa
    31921 tacctcttag aatcttatcc aaaatgcgct caaccataac aaaggtctta cctgagccag
    31981 cagatgctga tactaagata ttttgtccac tgctataaat agcctcaatc tgctgcgctg
    32041 tccgcttgtg cgtcttatct gataaggcct cctcctgctg caaacgagca atagcctctg
    32101 gcgttagaaa gccttcatca atcctcatgc tttatctcct cattcattcg tgtcaagaaa
    32161 gcctgtctcc tttcttttgt cggtaggacg actaggcgtc tcgcgtaccc tagatctaaa
    32221 tccgcctcaa agcgcgtgat ggccttgagc tggtcaccct gaacagactt gccgtctgcg
    32281 gtataagggt ttattaggaa atgccctgtt ttaatctgct tcaccgcaga caaatatagc
    32341 tgctcattat aagccagcag ggtttctagc tcatcagtct cataaagtgt gttgttaagg
    32401 tgatagctgc cattagccag atattccttg gcttgggcta aaaaaatgcc cttataggtt
    32461 aactccttgt aagccgcagc tactagctga tcatcaagtg ccttaaagtc agacagactt
    32521 agccttggct cttgcatgtg caggtacatg gcgccaaaca ggccctgccc cttattcttt
    32581 agggcagcaa gataggtcac aagctgagga ctcaagccat tgtaaaaggc aacaatgtca
    32641 aatacccttg cactggattt gtagtccaca atgcccagcc taccatcagc tagctggtca
    32701 atacggtcaa taacccctcg aataagcact tgctgaccca gcgctagctc aaaggcctcc
    32761 tcttgcttgg ttatctgcag gccttgatta aggtctaaga cagaggctgt tgagtaagca
    32821 atccccttta ggacctctaa gctatatcgc ccttcagcat cagcctgata aacctgctga
    32881 aaagcgcttt gctgattaac tgctgcaata gctgcgccta gcttttggtc aaaggcagca
    32941 ttagacctat ccttggttac caactcaaaa atacggtgca ggtattgacc atgaatgcga
    33001 gcatctgggt gaatagactc tggctcttgc agccctagga catatttcaa gaaatacttg
    33061 tattgattgt tataaaatac agtcaaggcc gatgaagaca gattcaaggg ctgctgactt
    33121 gaaaagcggg tctcaataac ctcaggtgct actggcttag tagtcaaatg atgctcaaaa
    33181 gctggaagac ttagctgctc atcggctagc ctacgtttca aataacgaag ggcaaccgtc
    33241 caaaagtttc tgtcctcact ggtcatgtca tctgcaattc cctgccgatt aatagccacc
    33301 aagcgagaca agagagcctt ataattgcca atatctgccg ctgagtgtga caaacggttc
    33361 tttccttttt caatgactgg aacaccaagg gcaattagct ccttcaggta aggagagaca
    33421 tcatctgagc tattcgttaa gcttgtaggc aggcttaaca ccagctcctg cgtcgctgca
    33481 ttaaacaggg aaagtgctgt ttggtgattt ttcttgatat tttcaaagct cggcacatca
    33541 aggcgctggt aagaggcagt ctgctcattg atgcttgccc tttcctgatc agagatcagg
    33601 ctggtgtttt ttgtctgctt aggaaaatgg gagcgactca ggccaatcgc aaacacaaag
    33661 ggcttggaat gcggctccac cagatcatag gatttgatag acacaacatc taaggtcgca
    33721 ggcactgtcc gataatgtgc tgtctgcatg cccatcttga tcagagctag acagtctgca
    33781 agggtcattt tttcctgacc aaacacctga taaaaggtct ctaaaatgcc tgtgaaggct
    33841 ttccaaacct cctcgtcctt ttccctatca gtctcccttc tactgcctgc tagtgcctca
    33901 aaattatcag ccagctgaat ggtcttaaaa aaggtcatta gcttatcaag tagggaagcc
    33961 cctagctgct tttgactctt aaagagctgc tggagaggag tcaccacagc aagtcgcagc
    34021 tgattcaaaa gaggcaaagg atactgacgt gaggaattta gggtaaaggg tcttgaaaat
    34081 ttggtgaagc cttgaatatc agcaaagacc aagtattgct caagctgatc cagctctccc
    34141 tcttgaaagc gcccaaagag tcctgatttt agtaagttga caatatcctc acgtcgccaa
    34201 ttgtatctgc ggcctctttc taaggattcg acaaattgaa ccaaggggtg agcagacatc
    34261 ggctcttgct tgccgatata ataagggatc tcaaatttct caaaaatagg accaatttgc
    34321 agctgataag acgccacatc acctaaaagg acaagcatat ccttatagcg ataaccctga
    34381 tagagcttct cacgaatagc ctttgcaaca tgctcaagct cctctttttg attgagcgct
    34441 tgccagatca caaccttgct cttgtccttg gcactgagct gccaatcaag ctttgaatag
    34501 tcatgattgg cttcaagaag ctgtgttagg cgagaaaatg acacatcaaa gaccttttct
    34561 gacgttgtgt agatcggctt ggtttgaaat tgctgtgcca gctgttggat aaacgcaagg
    34621 ctcgcctcgt agagatttcc cttggtaaag gctagtcgat aagccttttg actgatatag
    34681 gctccaataa cgatttcttc acaggcttcg tttaagagcg ctagcagctg ctcctcctca
    34741 gctgaaaagc gggtaaagcc atcaatcact aatacggtct gccttagctc gtcatctagg
    34801 ctcttgcttt tgatagcctc agcaagctga gccagcctac ttgactggtc gtaatctcct
    34861 tgtgcaatca gctgctcagc cttggtcata atcgtgatca ggtcctcttg cttttctggt
    34921 ctatcaagcg tcgttaagtc aaaggctgtc agattagctg cttgcaattc cttatatagc
    34981 tcaactaact gggcaataaa ggcctgatct gtccgtagcc ggtgaaaaac ctttagctca
    35041 tcttcttgca gctgcatgag cacacgataa aaaatcatgg ctaagccatt atcatctaac
    35101 gcttgtcgat tagctgcctt agctaaggta aaataacgcg ccatctgctc aaagcgggtc
    35161 accgtaatag caaaggaacc ctgctctggc aataaggcta ggacagaacg ttccttttca
    35221 aaggatagag agttaggagc aatataaaag acacgatagc ccttatcagc ataagctctt
    35281 gcctctttga ctaaaatctc tgtcatggaa tagctaatct ctgtgtatag taatttcata
    35341 aaactccttt tatttggacc tgatacaacg tctatgcctc cattataaca aatcagcctt
    35401 gcttttccca ttgttaatga tctttcaaac gccacaagaa gcgctcacag catgaaaaaa
    35461 gcctaccatt tcacatctgc tgctttgcgc aagaaatgat aaggctttgt cttgtatagg
    35521 ctcaaaaaac agactaagag ctcctagtta agctgccctg tgcttgtctc ttgtgatctg
    35581 tccccaggca ttctttttac gctgataacc aataaagctg ctcaccttga taagggttaa
    35641 taccgtatga agaacaaggc attggtagat ggcagcatag attacccaag ccatatcaaa
    35701 aagagtaatg ctactattgt tttgcaaata aaccctattt aaaaacgatg tcaacgcaat
    35761 aagcacacaa tagcaaatat agagcagcat cagtgacaca aaaaaggttg tgtttaattg
    35821 atggcatagc aaagacagca caatgataat aacaccaaat gcctcaataa aaggagataa
    35881 aagctcaaac aaaagataca gcacatagga aatgagtacc gtcgctttaa accgacagct
    35941 tacaaaaaac tggagatact ttttcaagca ttgatacagt cctaaaaacc aacgacgcct
    36001 ttgccgacac aaatccttca agcgactggg cgcttggctc cagcaaatag cgtctgtttc
    36061 atagccaata cgataaggaa tcttgttgtt atggcagaaa aaatgtaatt tcatcaccag
    36121 ctccatatct tctcccagag tcccagtgtc ataaccatca acagcaatcg caagctcttt
    36181 tttaaacagt ccaaacgctc ctgatatgat taaattccca gcagcctggt ctaataaaac
    36241 acgagctcca aaaaaggcac aatcatactc aattgcctgc gcacacgaaa taagctgacg
    36301 cggcaaatgg tagtctacga tcctcccagc tgccaatgct actccctgcg aaaccttgac
    36361 catgccccca acagcaatga cagacggatc ctttgcagca gtctttgcaa tacgcttaag
    36421 cgaatcctcc tgtagcatcg aatcagcgtc catgcacaat aaataatcgt attgagcagc
    36481 gttaatccca agattgaggc tatctccttt gccgccattt gccttttcaa gcagggtcag
    36541 cttgatatgc ttgagctgct tttggcttac agcctttaga gggcgtgttg ggatccgctg
    36601 attaatcgaa caagtcaccg cttctaaatg aaactgctcc ttcaagagct tggcggtatg
    36661 atctgttgac ccatcatcaa tgacaataat ctcatagcag tcataatcaa gcatcagcaa
    36721 ggactccact gtttcgataa tggttagctc ttcattatag gccggaacca aaatagacac
    36781 tggcggtaaa gaaacatcac caccaacagg cgcttgctgt cgcctttcat aaaggtgaat
    36841 agtcccaaca attaaggata gcagtaaaaa gctcgcatag gcaatcaaaa acgctaaaaa
    36901 aagatattgg gagtatttca atactaaaaa cagtagctgc actatcattc tcctttaaca
    36961 tgcaatcact tgtgcttacc attcgcctta caaaagcgtc tcaaggtctg cttcatcaaa
    37021 tacccgatat taaaggcaag gatcgctaag caaacgatta tataaaaaaa caacaggtaa
    37081 taaatcatct tatcttctcc tcttttcctg ccagacagcc tgcacctgct gataggaggt
    37141 ctttaaaact tctcttaccc ttggacgctc ccagctcaac agtggatact ctaccattgc
    37201 aatgaccttt gattccttta gcggtgcaaa accaatagct attgcttcaa tggctaattc
    37261 ctcaacacca tagtgctcaa aataatcatc gtgtattttg tttgaagctg gatcagaaaa
    37321 attgagcagc tgccagggaa tcctaagctc aatcagacgc tcgccaaaag aaatatcggt
    37381 ctgcgaatca aaatgagccg agcctcgttt gccattgccc tgttttaatt ggccggtagg
    37441 gtagcgcttc agtcctcttt ttgcaatcgg aacctgatca atggctgcaa aaataccatc
    37501 atttctcacc accatatcaa ccatagtaaa tcttggcgta tgcttgttag ggggaaagac
    37561 ataaaagtcc tttccattaa tctgcctaag gtaattggca tcagtagcat ggtagcgctc
    37621 ctgcaccaag aggcgactgc ctttgtggtc atcaacaaca agggcaaaat cagcaaagcg
    37681 atcaaaccga gcgctaaagc cttcaataac cctgctgcct gttttgggcg taatgtctaa
    37741 gggaatgagc cactgtcttt gtaagggctg cttttttgtc gattcaatag caatatagag
    37801 gtatttttcg tcctgatcaa cgaggagctg ctgcccattt ttcttgtagg ttagagctct
    37861 agaccactca tctgctgcct tttgcccatc aatagcatgc gtccttggag catgctcaaa
    37921 ggttaagaga ccataacctt gagccttaga ctgaacatca ccccaaagaa agctttgatg
    37981 tttattggtt gcaaaggagg tattccagct cctagcagtc caatcgtcct gccagctatg
    38041 gatcgttgca ccacagcagc cagacgcaat aaaggctgtg taatctgcca tcaagcgctc
    38101 gccttgatcc ttttctgtca aagggctgga agtcgatatc atttggtcca cacctctggc
    38161 tgtcgaatag ccatagcccg tcacaaccac tgggacacga tgatagctcg tcagtagctt
    38221 gacgtatccc tgatataagg gcatgcgctt aatatcccca acaagcctat cagtaagccc
    38281 tagacggtca aatagcagat aatccctata agccgagtga caatccaaga gcttatagga
    38341 agcaaaaaga ccggccttaa ccttagcgct gggcttaata ttttcaatcg tcagttgaac
    38401 atattttgct gcctgagagg caaagggatc ctgatagaca aagggatctg attgaggcgt
    38461 atttgaaaag ctcaccaagt gctgccagcc atatttgcgg ctctcgtatg acgtgatttc
    38521 ctccatgatt tcagccagta tagcctcaaa ccgattggcc tgaggtgtcg ttgcataata
    38581 ccttccctta aagcctacag gcttggcgtg attctgatga ttggtatagg ctatcgtccc
    38641 actgtaccaa tcatcaccaa caatatagcc gagtagccat ttactcatat cctgatcata
    38701 atgctgaagc cctaaatccg aatgccagat ccgttttctc ccatgaatca catcaacact
    38761 agccctagct tcccttaaca gagtgcctaa ataagcctta tctaaggcgc tgatagaaga
    38821 attgtcatga taagcatcta ttctaaagcc ctgtaatagg tacagaggat gacttgctct
    38881 gtcattgtag cgtctcaaag catggtaaaa agtgacgggc ataataaccc ttaccctgat
    38941 cgtatttgca cccatagctg ctatttgctt gaaccaccta tagtaggttt tctcatcaac
    39001 gctaaggtct cgtcgacgat agcctgctat ggaactctcc acatcaacac ccttgatgag
    39061 ataaggagat cccttttgat catatatgcg cttgtccttg gtgtaaaaga ctgtccgaat
    39121 agctgactgg ttagagaccg gcaggtacaa gcgaccatca atatcacaac aataatagct
    39181 caagccaatc acagacaaga gcaaaccaac aaagattaaa tatttcttca tcactaccta
    39241 ctccaataat gtattggtat ttttagacgg tgcactgtac tgatagagcg tctcaatatg
    39301 cttatccagc catcgcccac gacgtctaat aaagtccttt agttgcttaa cagaggcctc
    39361 atagctactg tagttacgac tggctggcac aaggtaatta gtggcatcgc ttcttgatgg
    39421 cactgtaaac acatagcccc acttatgata attgcgctga atagccggac ctaaaaaagc
    39481 aaccgtagca tcaatatact tgatcaaata atccgttgat aaaacattct gtcggagctg
    39541 atgatacctt gtgaccacca gcttaacaaa gctaggatcc tttagcagca tgcaaaacca
    39601 aggagcatct gatagggtaa agtccgcctc atcataagga gcctcaatct gattatcaaa
    39661 ggcgttgtta aaatcccaga ccaccagctt gagcttatcg cgcaaatcct tataaagata
    39721 ggttgaaaac ttcccagcat caatatttct aaagaattca ttgataataa aatagtctgc
    39781 aaaggactct tggtccagat aatcagtgta ttgctttaaa tcataagaat ataggagctt
    39841 ttcgatatga ctgatatcct tttcaataaa ctgcttttgc ttaggcgtca gacggtgcag
    39901 gcttgggtat ttaatgtcta aagaggacag acctgcttga ttcgtatagg atacgtaatg
    39961 atcaagagcc tgcttagcct tgtgtcttct atcccaaaca aggatataag gcgttttatc
    40021 agattttcta tcactttttt cgatgtttac cctatgccgc ccctgctcaa tactctccac
    40081 agccaaatac agaccacaat actgatgatc caccactaac tcgcaatacc tgacgttagg
    40141 tgcataggtc atgatctcac cggcaatatt gtagctaaga taatttcgga ctagggtccg
    40201 atctaaaaaa ggaccatgca gcacccactc agactccttg gacatgccag ccagcgagac
    40261 tgcctttggc ttagctcttt tattgataaa ccttagcttt aaggatttct tgtcaaaatg
    40321 acgtgacgaa ttgcccctat aagcaatcaa tgctgtcaag gacaagcgcg gagactcaga
    40381 caggctgtgc tctctatcta gctgatcacg aagcgagacc gtcgttttaa tggttttttg
    40441 ccgctttgtc tctccctcgt attccctttg ctctggaatc tgctgatgat gagtgtcaat
    40501 gctaataatc ggcaaatgag agctaaactc cccagtgctt ctggagctct ttttgaccgt
    40561 ctgcaaatgg tgatgaatac gctttgcaga ggtcttagga aaaccgatac cacaaatagc
    40621 agctagcaag agacacacca gcacaatcac ataaatcgtc ttttctttca tttacgtcaa
    40681 ccagttatgt catcgctttg actaacaata ttaaaataat caactcgccc cagctgataa
    40741 acagcctcag ttaacggatt agcctgctga taggtgctgt cataatcctt tcttgacagc
    40801 tcaaagatca tctcaatatc atcagacgtg gtgtttttca cgctctggat cgccttaccc
    40861 gaaaagtagt taaacactaa ccgctccagc tcaatttcca tttgcttatc acagcgaaca
    40921 atcaacaaca gtctattgtc atttctgaca gctcccataa gcaacaaaag cataaagatc
    40981 acgctgctac cagttgcagc gacagtataa tcaccaacac cacagcaaat cccaaccaca
    41041 atcgtccaaa aaatatagac tgtatctcta gagtctttga ttgctgtccg aaaacgcaca
    41101 accgacagcg caccgaccat accaagagac aaagcaacat tatttccgat aactgtcatg
    41161 acggttgctg ttaagaccgt caaggtcatc aacgaaacat taaacttctt gctataggca
    41221 gtcccagtgt gggtataggc atatgacata taaatcacaa tacttaacaa ggctgcagca
    41281 acaatatgca gcaaaacatc ttgaaagctc aaggtcccac gctgttcaaa gacatgtctt
    41341 aataattgtt tcatcttaat atctctccta aaaacgataa tgcttgctga tagctctccc
    41401 catgcaatac ttgcttgcac ttagctcgct accattaaca gactccaaaa gctttttgat
    41461 ataagacaac aaaaagccat tatacttgac ctccaagatg accaaatagg gatctagcag
    41521 gtaattctga ggcagatgat ctgaaaaaat atcagcattg gtctcagacc cgataatatg
    41581 atgatcaaag gtaatgcgaa tattgttttc ctttgccaca aatgccttgc gctggtattc
    41641 gatcactgtt tttggctgat agagctgcat tgacatgcga ctatagcatt cagcagcaaa
    41701 gcgatcagga taagtcagca atatagactt gtctccctta atcaacaatt gagcgtctgc
    41761 tctggtcaac ctcagagatc gctttttttg attgctccct tgcttttgct tcatctccaa
    41821 cttagcaaat gagctctgac taccgtaatt gcgcaggcga atttttcgcc taagctcaat
    41881 accgtcctct ttttcctgcc agtcaacgtc ctccaaagaa tcaaaataca aggatcgaat
    41941 cacatatccc tcactagagc tatgagcatc tagacgcaag agcttggaaa attcatgcga
    42001 taagcgataa taatcctcaa tggtaatcaa atactttttt tcttgacgca atacctcatt
    42061 cacgccagtg tcctcctttt tcgtctgtaa gcaatgcctt aacaccaagc tgcctgtaac
    42121 agcagccaac aaacctgtct cataaataag tcagggcaaa taaggtgatt gttggctcta
    42181 caagagtcaa tcacctgcca aaatagtaaa tcctgccatc tgttgaaata atataaacca
    42241 gctgatcgtc ttgattgcaa gacaggcgct tttgtgactg atctagctgt ctgctgctaa
    42301 tatcagttgc attagcctcc ttgagcatgg cctgcttgag ctgttgctgg atttttctgg
    42361 cttgcagctc agaaatctca aagctgccat taaccttttg agccttgtgc ttgtagacca
    42421 gtgccacatg gtctttagct gttgtcctag cagtcgacag gagcccttct ttgttgagct
    42481 gagtatgctc tcctacatca atggcaacat agtcataggg tgcccgtatc cggtgcgctg
    42541 ttagtattga ggacaaaatc cctgtcacaa ggcagatgct tatcgtagcc actatcatct
    42601 gctgccgctg cttacgaatg aaccttgaaa aagcacagac ctccgcctga tattcctgaa
    42661 gctcttcttc aaccttactg taatcctgtc taagatcagc caagtcagtc tgacagtcct
    42721 tgcagcttgt cagatgagcc tcaacaaccg ctctactata atcactcaac gtatcatcta
    42781 catataatgg caacaaatcc tggatcaact cacaatcata cttcatagcc atactcctct
    42841 cgtaattgtc ttttaatatg ttttcttgcc ctaaagacaa gaaccttggc agaggatact
    42901 gtgatgccaa tatccttagc tattttttca taggaatctc ccgaataaat cctcgccaga
    42961 aagacagcct gcattttctc tggaagatta aaaataatcg ttagtgtaat ctctaacagc
    43021 tcccttcttg ctatcttatc aagtggttca tcatgccctt tagcatcaac gatttctaag
    43081 ctttccatcg acatattctc atattttttc tttttaattt ctgtaaagaa ggtgttcttt
    43141 gcaatggtaa ataaccatgt tttgattgaa ctatccccac taaatttagc aatattacga
    43201 taagccttta gaaaagtctc
//
LOCUS       DARYYD010000014        40365 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.014, whole genome shotgun sequence.
ACCESSION   DARYYD010000014 DARYYD010000000
VERSION     DARYYD010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40365
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.014"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            255..782
                     /locus_tag="TV188_000668"
     CDS             255..782
                     /locus_tag="TV188_000668"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEL1534047.1"
                     /translation="MIKKDYRQLVLQRLAMMTPEDKLEKDLALLAAVVASSSYQEAQT
                     LVTYLPLPHEYQSHLLIERALQDGKTILVPKTRSRGEMVFVAYDPCDLIQTAFGLMEP
                     RCTIAVAKSEIDAIHVPGLVFHPAGYRIGYGGGYYDRYLRDYQGATFSTIYACQWEDF
                     VVEAHDIAVKEVYCQ"
     gene            779..1171
                     /locus_tag="TV188_000669"
                     /pseudo
     CDS             779..1171
                     /locus_tag="TV188_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
     gene            complement(1278..2186)
                     /gene="galU"
                     /locus_tag="TV188_000670"
     CDS             complement(1278..2186)
                     /gene="galU"
                     /locus_tag="TV188_000670"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEL1534048.1"
                     /translation="MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEE
                     ALKAGIEEILVVTGKAKRSIEDHFDSNFELEYNLQAKGKTELLKLVDETTAINLHFIR
                     QSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNPSAKPLTKQLIEDYDCTHASTI
                     AVMRVPHEEVSNYGVIAPQGKAVKGLYSVETFVEKPSPDEAPSDLAIIGRYLLTPEIF
                     AILENQAPGAGNEVQLTDAIDKLNKTQRVFAREFKGERYDVGDKFGFMKTSLDYALKH
                     PQVKDDLTDYIIKLGKALESTQQQTK"
     gene            complement(2236..3441)
                     /locus_tag="TV188_000671"
     CDS             complement(2236..3441)
                     /locus_tag="TV188_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HEL1534049.1"
                     /translation="MKISVAGSGYVGLSLSILLAQHNDVTVVDIIDEKVRLINQGISP
                     IKDADIEEYLKNAPLNLTATLDGASAYSNADLIIIATPTNYDSERNYFDTRHVEEVIE
                     QVLDLNASATIIIKSTIPLGFIKHVREKYQTDRIIFSPEFLRESKALYDNLYPSRIIV
                     SYEKDDSPRVIQAAKAFAGLLKEGAKSKDTPVLFMGSQEAEAVKLFANTFLAMRVSYF
                     NELDTYSESKGLDAQRVIEGVCHDQRIGNHYNNPSFGYGGYCLPKDSKQLLANYRGIP
                     QSLMSAIVESNKIRKSYLAEQILDRASSQKQAGVPLTIGFYRLIMKSNSDNFRESAIK
                     DIIDIINDYGVNIVIYEPMLGEDIGYRVVKDLEQFKNESTIIVSNRFEDDLADVIDKV
                     YTRDVFGRD"
     gene            complement(3694..4947)
                     /locus_tag="TV188_000672"
     CDS             complement(3694..4947)
                     /locus_tag="TV188_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1534050.1"
                     /translation="MRTLKNLITVVAFSIFWVLLIYVNVYLFGAKGSLSIYGFLLIAY
                     LLVKMSLSFFYKPFKGRAGQYKVAAIIPSYNEDAESLLETLKSVQQQTYPLAEIYVVD
                     DGSADETGIKRIEDYVRDTGDLSSNVIVHRSEKNQGKRHAQAWAFERSDADVFLTVDS
                     DTYIYPDALEELLKTFNDPTVFAATGHLNVRNRQTNLLTRLTDIRYDNAFGVERAAQS
                     VTGNILVCSGPLSVYRREVVVPNIDRYINQTFLGIPVSIGDDRCLTNYATDLGKTVYQ
                     STAKCITDVPDKMSTYLKQQNRWNKSFFRESIISVKKIMNNPFVALWTILEVSMFMML
                     VYSVVDFFVGNVREFDWLRVLAFLVIIFIVALCRNIHYMLKHPLSFLLSPFYGVLHLF
                     VLQPLKLYSLFTIRNADWGTRKKLL"
     gene            complement(5344..5964)
                     /locus_tag="TV188_000673"
     CDS             complement(5344..5964)
                     /locus_tag="TV188_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534051.1"
                     /translation="MRKYLQIRLYELSHYVEIIISIILVISLLVLTGRLALSLTGIFT
                     IKSGIDTYLQSFLNQAMSIAIGVELIKMLSKHTSGTIIEVLLFAIARQIVVAHGSAKD
                     SLLSVIALAILFATRKYLFTSFDDTSSIIVRGSQKVKIANVLARVELPVINKNELMRD
                     LMLRHLEEEGKTATIGASIAFSDVALRVDHMHEGVITRIEIIKSLK"
     gene            complement(6005..6100)
                     /gene="ffs"
                     /locus_tag="TV188_000674"
     ncRNA           complement(6005..6100)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="TV188_000674"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            6277..7503
                     /locus_tag="TV188_000675"
     CDS             6277..7503
                     /locus_tag="TV188_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1534052.1"
                     /translation="MKNKLSLFLLAALTIVGLSACAWRSNPLADKEQQFGLTGARRQQ
                     VLDQIDQRYYYQQLSQAEKENYLLLYDSLSAFHEVTSLAPASKHSLMTTIDAFMMDNP
                     AFFWITSANYRLERSDQVAFVTFPLPEKVEQTYHRLQAIGDDIIADMPATNDYERVRY
                     FYEWIIKQTDYNRDAFEAYQSGHEALIASNQDIRSVFLDHLSVCNGYAQAFQFLCQKA
                     GIPVAYIRGSVTFDRSQDVFTHAWNTVQIAGKNYAVDTTFGDPVFDQNESIKQLEVNY
                     NFLCLPDQLMKQSHQASRDIVINQTETLTDVWTIPECSDDSLLYTKLNHSYFTAFDRP
                     DILASLEQQLRTNQPQTSLQFANQDLYNQMVSDLEQHSDSYHSLFQAYWPNAAGYFYS
                     LHPSTFSISISIINQQ"
     gene            complement(7613..8107)
                     /locus_tag="TV188_000676"
     CDS             complement(7613..8107)
                     /locus_tag="TV188_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEL1534053.1"
                     /translation="MSYSKQEQEYFMREALKEAEKSLLKDEIPIGCVIVKAGHIIGRG
                     HNAREERNQAIMHAEIMAINEANAHEGNWRLLDTTLFVTIEPCVMCSGAIGLARIPHV
                     VYGASNQKFGGAGSLYQILTDERLNHRVQLEVGLLADDCAKLMQTFFRQRRDQKKQDK
                     ESKI"
     gene            complement(8104..8886)
                     /locus_tag="TV188_000677"
     CDS             complement(8104..8886)
                     /locus_tag="TV188_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1534054.1"
                     /translation="MKLTTLGSWGAYPYQDAGTTAYLVTGHDGFQLLMDAGSRSLNEL
                     EKEINPLDLDAVIISHYHPDHVADLGVLRHYYQLYPRHLGKPRLLPIYGHDEDEAEFA
                     KLTLPGVSKGIAYQVDRVEALGPFDITFIKTVHPVVCYAFRIVERATGQVLVFTGDTG
                     YFEELADFAAEADVFLADVYLYEGNEHHMAHLTSKEAGQLASRAKVKRLVLTHMPPLP
                     PEGIDPKRHLEVLRQQAQGYAGQIPVDLALPHRAWDLGSLSQ"
     gene            complement(8985..9524)
                     /locus_tag="TV188_000678"
     CDS             complement(8985..9524)
                     /locus_tag="TV188_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEL1534055.1"
                     /translation="MLSTKDLVKVAMMTTLIIILGLIPAIPLGFVPVPIVLQNLGVML
                     AGLILGGKKGTLSILLFLVIGLFLPVFSGSRTTVPVLMGPSAGYVLAWLFVPLVFAFL
                     YRSWLARYRSLAFLAIFISGVLLVDLLGTIWLAVYTDMPLTRSLVASLVFIPGDTIKA
                     VIATALAVSYKDSFLNTNS"
     gene            complement(9528..9839)
                     /locus_tag="TV188_000679"
     CDS             complement(9528..9839)
                     /locus_tag="TV188_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534056.1"
                     /translation="MRNCFGIALDQEYRCVHYHTVLDIVGLKCARCQAYYACYHCHDT
                     LQDHAFEPTDHKETYPVICGHCRQLLRRSEYECGSCPFCFSPFNPAYHKHQDIYFSKE
                     L"
     gene            complement(10226..10363)
                     /locus_tag="TV188_000680"
     CDS             complement(10226..10363)
                     /locus_tag="TV188_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003585727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1534057.1"
                     /translation="MHQNPTERSVLLSTYEALQLMLAFGSFLLTLISLVVAIVILNNK
                     K"
     gene            complement(10747..11991)
                     /locus_tag="TV188_000681"
     CDS             complement(10747..11991)
                     /locus_tag="TV188_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1534058.1"
                     /translation="MRNKKTSIRLVQKYGICSAVVALATIASLGIGNDVRAEDFTYPS
                     MYNQGYFFQQFIKKEILNPGSGSSSDWETSTHYNNGRMLENVLRYLWRVEQFLKKSTG
                     QSEQLYKLYEKDSLGIPGPQGPMGPAGPQGLRGERGPVGERGPIGPQGPEGKPGQQGP
                     KGDTGPQGEPGQQGPKGDIGPQGEPGLPGPKGDTGPQGAPGQQGPKGDTGPQGEQGLQ
                     GPKGDTGPQGAPGQQGPKGDTGPQGEPGQPGPKGDTGPQGEQGLQGPKGDTGPQGAPG
                     QQGPKGDTGPQGAPGQQGPKGDTGPQGVPGQQGESQKVPEVPKAPETPEKKEQPQAPK
                     EPETPKAPEQSPAPQAPKSSEQPASPKAPAPQSAPNKSAAPAAQKGTLPATGEANHPF
                     FTLAALSVIASAGVLGLKKKQD"
     gene            complement(12421..13563)
                     /gene="tgt"
                     /locus_tag="TV188_000682"
     CDS             complement(12421..13563)
                     /gene="tgt"
                     /locus_tag="TV188_000682"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEL1534059.1"
                     /translation="MTNYPITYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEIGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQAILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAADLVSMDFPGYSI
                     GGLAVGESHAEMNAVLDFTTPLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSEGRLVVKNAKFAEDFTPLDHHCDCYTCQHYTRAYLRHLLKADETFGMR
                     LTSYHNLYFLVNLMKQVRQAILDDNLLEFRQDFLERYGYNSSSRNF"
     gene            13968..14813
                     /locus_tag="TV188_000683"
     CDS             13968..14813
                     /locus_tag="TV188_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEL1534060.1"
                     /translation="MSIREIKREARQTLKGLKGKYLLFLVPIILSIFYSGIEVHQTYV
                     TTQGIEVSVGASYFPLIVLIMLTVFTLSAAYTMLDVIRYYRREVSFSEATIAFSGNLF
                     GKVLVLLIIKGLLFILWSLIWIVGLVILTISSAALLTSYNTGAAVMTPIIFMVIGFVI
                     FIIGLIVYMNRYCAYSMAEYILYDKVKEGTYMGAITAIEESKDMISGYKGKYFLLHLS
                     FIGWFILVILSFGLIYIYVLPYYTTADVTFYHHLKHIHDETELPIDAERLTITGSKEA
                     PSAIS"
     gene            complement(15009..18971)
                     /locus_tag="TV188_000684"
     CDS             complement(15009..18971)
                     /locus_tag="TV188_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NPCBM/NEW2 domain-containing protein"
                     /protein_id="HEL1534061.1"
                     /translation="MFKPYTDGKQRFAIKTFKTGAASVLVATLFLTLGLTTVSADEQQ
                     VTASAAIATTLEAQEAVDQQAADQSATAAQDTAAEGSSETLPVVIGTATTETTDSKSQ
                     VAAAEQATEASAEETTKQEQTEVSQAVETTNKTEAKDYIYLSDETRVNPSKVGHGSFL
                     QDKNPAGGTITLVVDGEVLAFDKGIAVHAPSQLYYDVEQYSNEYTRLSAYLGVDYSRR
                     GKDDGVSFNIYKSKDGKSWESLVTTGTVTGTSEAVYVDLDITGAKYVKLIANSLKNNG
                     NDHSVYADLRLLKTDYDLSSEVSYDRLKTTEEYDALLSKNSVTDNYDNPDNLALVLER
                     EFVNRVGYHTIQSAVKKNEKVKVALDWLLSDEDALSLFLEAGSMFNGSTLKTLNALGD
                     LYATNKADLEDKGNGYVYKKMMLATAVAYCKEIKSFVVNYGGTYLASDPVLKYQAFKE
                     LYRDNEFLRKEEFANYNMELVRAVMDAKIDDEEILWLHHYAEQKYGDKVASYTSGYSY
                     TKYKNIGYGGADMRSADNQAQWTEKYQLVGTLNDDAFNVTYDNRHRIWMLMEKGAVCW
                     GLSNLGVAVNEVFGIPAVNIYQNDHEAYLVYRQDDQGNGIWDIRDNVYGNRWAISYSR
                     WGTTTATEARLLLGWGLKSYNDIHKNASYMLLAQAALNQYDKFKESLYYNLIANVYEA
                     GSDQQIEAYSKALDVLELNLDTYDGLIEAYAKNGQKTDQDWLDLGKRVIAAYTYYPQV
                     MVEAIKRITPNISDQAAKAELDLLSYNALIAAKTATDKEVLQSNEVRIIANYILTGNP
                     IETASFSFDDKTLRLHENYQDTDLTVRYSIDNGKTWLETKDKVIVFSDDLLAKLNIED
                     GILVGFDAVSATYRINLTKAAAPTNSSLYGNDLENRLIGAIEHLEVSLDNGQSWQAYD
                     GTERFNDTVTVLARYRAHGTSLASDSVTYTFTADSTDPTMHYISIDDIQAVTYANEQS
                     GRSGKHMVDGRDMATQWHTLFNQVTEDKSYTVEFKDDKNFSAIAYLPGGVNGMIHSAK
                     VDISSDGKVWTTVVDSTDWKQNTELKTVSFTPTTGRFVRITALDTYGKSSGQANKFVS
                     GSAYRFFEDISSPIEAPVRNDILALKDSILTILKETNTATKEIESFAITNSGLTAATT
                     EKNQAIQGKILETIKDLGLTGTYYITLENTGTYDDLADLLNHQLVITYQDKAAGPLYV
                     LAMNSLSSGDEALDAEYSLDLIKSALKSALESENIDLKTFEGLSISSQLPAAKTAVNT
                     ALMEKLQQLLPGDYFIDLAGLPTAASIDELLDSQLFIYYRESHWTTAYALDRGAFQQL
                     "
     gene            complement(19106..20923)
                     /locus_tag="TV188_000685"
     CDS             complement(19106..20923)
                     /locus_tag="TV188_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HEL1534062.1"
                     /translation="MKKFTKRCLKGCGLVGLVFSTGLVALSDNIDSALTVGAETTTAS
                     AFENNGTGQHLNWHIDIPQEYTVELGEPITISDLMSQITVTRKGSNGTVNDGDTFDFI
                     SNGDGSRGIDTPGVKIWFDFYNAAGTSFLTDEMLASPTYAVPGGSYTIKAWVFYGKND
                     TKKLFTFKLKNSNSNKTELRKSLEEAKLKLSQPEGTYSDESLQALQSAVTIGKTYLNS
                     DPDQNTVDQSVTTIDSAITSLVNLNALNEAINQATPFITDGKEYPKEAYDGLVQKLAA
                     AAKLQNSFGPSQGDVDKAATDLTQALTTLKTAVAHEALDQALAKLLELYRENPNLALT
                     SESLKELYNKAIEAAGTFYRTVNKDKERKDISLYELERYTTETNSVVDTILKVKAAIA
                     EEGKAKLRSALDQLNALIGENLDLSPYTAASAQAYTDQLAKAKEVAAAGETAYAQETE
                     PTAITNSLVKVLNAKKSLSDAKAALVAKPVDPVDPVDPVDPVDPVDPVDPVDPVDPVD
                     PVDPVDPVDPVDPVDPVDPVDPIDPADPVKPSDPEVKPEPKPESKPEAKKEDKKAADK
                     QQVLPATADTANPFFTAAALAVIACAGQLAIVSRRKESN"
     gene            complement(21283..21756)
                     /gene="perR"
                     /locus_tag="TV188_000686"
     CDS             complement(21283..21756)
                     /gene="perR"
                     /locus_tag="TV188_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HEL1534063.1"
                     /translation="MDIHSHQQALNAYENVLEHLRDKHIRITETRKAIISYMIQSTEH
                     PSADKIYRDLQPQYPNMSLATVYNNLKVLVDEGFVSELKISNDLTTYYDFMGHQHVNV
                     VCEVCGTIADFMDVDVMDIAKEAHQQTGYKVTRIPVIAYGVCPSCQTKQGKDTDY"
     gene            complement(21793..22245)
                     /locus_tag="TV188_000687"
     CDS             complement(21793..22245)
                     /locus_tag="TV188_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEL1534064.1"
                     /translation="MIDTFQNPSDETITSYLESSKTIAVVGLSDRQTTAAYDVARFMQ
                     AKGYRIVPVNPRLAGQSVLGEVVYASLAAIPFKVDIANVFRRSEYLPQVAQDFLACQG
                     QVFWAQLGLYSQEAEELLRSAGKADIVMNRCIKIDYLRLISKQDQDSC"
     gene            complement(22485..25127)
                     /gene="polA"
                     /locus_tag="TV188_000688"
     CDS             complement(22485..25127)
                     /gene="polA"
                     /locus_tag="TV188_000688"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEL1534065.1"
                     /translation="MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGF
                     HLMLDHMMKRVQPTHVLVAFDAGKTTFRTELFADYKAGRAKTPDEFREQFPYIRDMLG
                     ALGIAFYELEHYEADDIIGTLDKMAERTEIPFDVTIVSGDKDLIQLTDANTVVEISKK
                     GVAEFEEFTPAYLMDKMGLTPEQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEYGS
                     LEGIYEHIDSFKPSKMKENLLHDKEQAFLSKTLATINTSAPITIGLEDIVYQGPDLDR
                     LSQFYDEMDFVQLKNALASQLPQEPVAEIAYQEVTDIRADMFSDDTVFYFEALRDNYH
                     REELIGFAWGNQGQIYASADISLLTTKLFKKVLEQPIATYDFKRSKVLLSHLGLDLPA
                     ASYDARLANYLLSTVEDNEMATLARLYTTISLDTDEVVYGKGVKRAVPDKAVLLGHLA
                     RKVQVLLDSRPVMLDKLAEHEQADLYTDIELPLANVLAKMEIEGIAVNQDSLQEMAEQ
                     NKVVIEELTQEIYEMAGEVFNINSPKQLGVILFEKMQLPLHLTKKTKTGYSTAVDVLE
                     RLAPIAPIVAKILDYRQITKLQSTYVIGLQDYIMADGRIHTRYLQDLTQTGRLSSVDP
                     NLQNIPIRLEQGRLIRKAFTPSHDDAVLLSSDYSQIELRVLAHISGDEHLIAAFKEGA
                     DIHTSTAMRVFGIEKPEDVTANDRRNAKAVNFGIVYGISDFGLSNNLGIPRKQAKAYI
                     DTYFERYPGIKAYMERVVREAKDKGYVETLFKRRRQLPDINSRQFNVRSFAERTAINS
                     PIQGSAADILKIAMINLDQALVAGGFETKMLLQVHDEIVLEVPNHELAAVKALVKETM
                     ESAVSLAVPLRVDESAGKSWYEAK"
     gene            complement(25551..27281)
                     /locus_tag="TV188_000689"
     CDS             complement(25551..27281)
                     /locus_tag="TV188_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HEL1534066.1"
                     /translation="MENLLQTTLPVAQLVEQLTEWLTKTFSGFFDLLQLVGNALMDWI
                     TQTLLFINPLLFMLLVTCAMFFLARKKWPLPIFTLLGLLFVYNQGLWAELINTFTLVL
                     VASLISVLLGIPLGIWMAKNKIVHQVINPMLDLMQTMPAFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLALRHIPTELVEASDAFGSTPKQKLLKVELPLAKHTMMAGVN
                     QTMMLALSMVVTGSMIGAPGLGREVLSALQHADIGRGFVSGLALVILAIILDRMTQHF
                     NGKPQERTQTGKTKKWLGLAALAVFLLSALGRGFAAMLSSSADKGQKVTIAYVQWDSE
                     VASTHVIAQVLRDEGYQVTLTPLDNAVMWQTIANGDADFSTSAWLPVTHQQQYQKYQD
                     KLDNLGPNLKGTKLGLAVPAYMSDVNSIEELSDQANQQIIGIEPGAGIMTAADKTQKA
                     YSNLADWELVAASTGAMTTSLDQAVKKKEPIVVTAWSPHWMFAKYDLKYLADPKKTFG
                     SKENINTIARRGLKADLPAVHRIVDHFHWEKEDMEAVMLDINQGMTPEAAAKKWVASH
                     ADKVAKWTQS"
     gene            complement(27299..28495)
                     /locus_tag="TV188_000690"
     CDS             complement(27299..28495)
                     /locus_tag="TV188_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HEL1534067.1"
                     /translation="MGTILEVRHLSKLFGKKQKAALEMIKAGKSKSAIFKKTGVTVGV
                     YDASFEVQEGEIFVIMGLSGSGKSTLVRMLNRLIEPSAGSILLEGRDISKLSVDQLRE
                     VRRHDMNMVFQSFALFPHKTILENTEFGLELRGVPKQERREIAKRALDQSGLLEVRDQ
                     YPDQLSGGMQQRVGLARALANSPKILLMDEAFSALDPLIRRDMQDELLELQETMKQTI
                     IFISHDLNEALRIGDRIALMKDGQIMQIGTGEDILTNPANDFVREFVEDVDRSKVLTA
                     QHIMIKPITTTVDLDGPQVALNRMHNEEVSMLMATNRRRQLIGSLTADGAIEARQKKL
                     PLSEVIDRNVRTVSKDTVITDILPLIYDSSAPIAVTDEQHRLLGVIIRGRVLEALANI
                     PDDDLN"
     gene            complement(28694..28936)
                     /locus_tag="TV188_000691"
     CDS             complement(28694..28936)
                     /locus_tag="TV188_000691"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534068.1"
                     /translation="MTSSYGQSKLTLCLADLIAIGSLLGSLSIGLVAGQESDRSIKSA
                     RGGCWVSSQGAKCQKGLLAVVCSGLLSAWLTSDITA"
     gene            complement(29001..30092)
                     /gene="ulaG"
                     /locus_tag="TV188_000692"
     CDS             complement(29001..30092)
                     /gene="ulaG"
                     /locus_tag="TV188_000692"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEL1534069.1"
                     /translation="MAKVQDITRESWILSTFPEWGTWLNEEIEEEVVPEGNFSMWWLG
                     NCGIWIKTPGGANVVMDLWSNRGKATKKVKDMVRGHQMANMAGVRKLQPNLRAQPMVI
                     DPFMINELDYYLVSHYHSDHIDINTAAAIINNPKLDHVKFVGPYECGKIWESWGVPKD
                     RIIVVKPGDSFAFKDIKVTAVESFDRTCIVTLPVAGAEENGGELAGLPVTDEELARKT
                     VNYIFETPGGTIYHGADSHFSNYFAKHGRDYDIDVVLNNYGENPIGIQDKMTSVDLLR
                     MAENLRAKVVIPVHYDIWSNFMASTDEILELWKMRKERLQYQFHPFIWEVGGKYTYPQ
                     DQDRIEYHHPRGFDDCFLEDSNIQFKALL"
     gene            complement(30287..31933)
                     /locus_tag="TV188_000693"
     CDS             complement(30287..31933)
                     /locus_tag="TV188_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEL1534070.1"
                     /translation="MIILDKKSYDLLSYLIRLKEAETVMAISAALGQSRRKIYYHLDK
                     INEALPSHVAQIVSYPRVGILLNSEQKAACQQLLNEVADYHYVMKGDERRSLSAIYIA
                     VATERVTLDKLMMINDVSRNTILNDLAELREELSSYNNKIQLHATKAKGYYFDCHPMA
                     LIQYLYKVLAGVYQGGNSSFIELFDHKLSETQGLSAYFSKEVLDYFHEYLFLSQASLG
                     KTINIQDSQFMLQILPFILLSYRNMQLHSETKTALKRDFNLIWKRKEYQIAKALASEL
                     YHNFKLHLDDIEVGMIAMLMLSFRKDQDHHVESQDYEQMRATIGDFIDQLELRYQLHF
                     THKKDLLRQLTRHCKALVYRKAYGIFSINPLTDHIKEKYEELFAMAQSCAVILEQAWQ
                     IRLTDDDVAYLTIHLGGELRHSHADWDKTKLVIVSDDGIGIQKLLLKQCQRYLPNCQI
                     EAVFTTEQYQSVFDLMSVDIVVSTTDALEALVPVLIVNPILSDDDIIRLIRFSKQGRL
                     SDSSRFSLELEKAIETIVKDDADRYALKTKIEKLIHHELL"
     gene            complement(32237..32953)
                     /locus_tag="TV188_000694"
     CDS             complement(32237..32953)
                     /locus_tag="TV188_000694"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEL1534071.1"
                     /translation="MAKRLQEMRERVCAANKALPLHGLVKFTWGNVSEVCRELGRIVI
                     KPSGVDYDQLTPENMVVTDLDGTIVEGELNPSSDLPTHVQLYKAWPEVGGIVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGPIPCARSLTADEVNGAYEKETGTVILEEFASRGL
                     DPMAVPGIVVRNHGPFTWGKTPELAVYHSVVLEEVAKMNRLTEQINPRVEPAPTYIMD
                     KHYLRKHGPNAYYGQKGSRH"
     gene            complement(32953..33816)
                     /locus_tag="TV188_000695"
     CDS             complement(32953..33816)
                     /locus_tag="TV188_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003100317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEL1534072.1"
                     /translation="MARPIGIYEKATPKHFTWLERLQFAKVLGFDFVEMSVDESDARL
                     ARLDWSKQERLDIVKAIYETGVRIPSICFSGHRRYPLGSSNPETEATSLELMKKCIVL
                     AQDLGVRTIQLAGYDVYYEEKSPETRARFIKNLRQACTWAEEAQVILAIEIMDDPFIN
                     SIEKYLAVEKEIDSPYLFVYPDTGNVSAWHNDLWSEFYNGHRSIAALHLKDTYAVTET
                     SKGQFRDVPFGQGCVDWEAMFDVLKKTHYHGPFLIEMWSENCETVEETRAAIKEAQDF
                     LYPLIEKAGLS"
     gene            complement(33821..34486)
                     /locus_tag="TV188_000696"
     CDS             complement(33821..34486)
                     /locus_tag="TV188_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEL1534073.1"
                     /translation="MMTHIPKLQVALDHSDLQGAVRAAVAVGHEVDVIEAGTVCLLQV
                     GSELVEVLRSLFPEKIIVADTKCADAGGTVAKNNAKRGADWMTCICCATIPTMAAALK
                     AIKEERGERGEIQVELYGDWTYEQAQLWLDAGISQAIYHQSRDALLAGEVWGEKDLNK
                     VKALIDMGFRVSVTGGLDINTLKLFEGVNVFTFIAGRGITEAEDPAAAARAFKDEIRR
                     IWG"
     gene            complement(34581..35066)
                     /locus_tag="TV188_000697"
     CDS             complement(34581..35066)
                     /locus_tag="TV188_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1534074.1"
                     /translation="MNLKKAFIENNSIRLGLSAASWQEAVKLAVQPLIDSGAVTSEYY
                     DAIIASTEKYGPYYVLMPGMAMPHAEAGVGVKRNAFALITLTKPVTFSDGKEASVLLT
                     LAATDPSIHTTVAIPQIVALFELEDAISRLVACHTPAEVLALVDESKNSPYLEGLDLD
                     S"
     gene            complement(35282..35560)
                     /locus_tag="TV188_000698"
     CDS             complement(35282..35560)
                     /locus_tag="TV188_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1534075.1"
                     /translation="MVKVLTACGNGMGSSMVIKMKVENALRQLGVTDIQSASCSVGEA
                     KGLASGYDIVVASNHLIHELDGRTKGHLVGLDNLMDDNEIKTKLQAVL"
     gene            complement(35675..37108)
                     /locus_tag="TV188_000699"
     CDS             complement(35675..37108)
                     /locus_tag="TV188_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1534076.1"
                     /translation="MKMLIAPLNWFSQDILQNPAFFVGLLVLIGYLLLKKPLHEVFAG
                     FVKATVGYLILNVGAGGLVNTFRPILVALGKKFELKAAVIDPYFGLAAANTKLEEMGS
                     ISVATTALLIGFGVNILLVALRKVTKVRTLFITGHIMVQQAATISVFVLLLIPQLQNA
                     FGAWAVGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAPFFGKKE
                     ENLDNLKLASFLTIFHDTVVASATLMLVFFGAILAVLGPDMMSNAELIGAGAFNPAKQ
                     AFFMYILQTSLTFSVYLFILMQGVRMFVSELTNAFQGISSKLLPGSFPAVDVAASYGF
                     GSSNAVLSGFTFGLIGQLITIALLVIFKNPILIITGFVPVFFDNAAIAVYADKRGGWK
                     AAVALSFISGILQVALGAVAVGLLGLTGGYHGNIDLVLPWLPFGYLFKFLGIAGYVVV
                     CVFLLAIPQLQFARAKDKEAYYRGEAQ"
     gene            complement(37591..38211)
                     /locus_tag="TV188_000700"
                     /pseudo
     CDS             complement(37591..38211)
                     /locus_tag="TV188_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104274.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(38213..38830)
                     /locus_tag="TV188_000701"
     CDS             complement(38213..38830)
                     /locus_tag="TV188_000701"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534077.1"
                     /translation="MKLSNLLVVGMKACLTGLLIHLLLIKANMTGERDFHNLVCYRLL
                     MPFPVIEGETADFVKVITLLGLSFNSFYFTISFLADLAEGTKEIFRFHARSQLVFFNK
                     LWRTSTIFYIKEWLLFIVLILGVLMTYYGAPYHIERLCYLMVSWLTIDICLIYVMIRY
                     ASSAVVAMILFASLTLIRYFLFDVWWCLLLIVLVHMLYDNYYKES"
     gene            complement(38817..39605)
                     /locus_tag="TV188_000702"
     CDS             complement(38817..39605)
                     /locus_tag="TV188_000702"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534078.1"
                     /translation="MLQYRLFPFRYFYPLVPLLFLGFIYFDSLKHILFFDTSAVDLSG
                     GIEVKKSLLLSMIRLDSVVFDFSFYQSFIYPLVMILVAYAYYYLKSRHLKYLIGRKSD
                     YGKRCIFLKLQLSLYVLLSFYIVIFALTLVSWLNGVAHMNGNLMPYFDQNSILRFFGQ
                     GATTFIAYYCLVKSLALFVHTYFVCFLVDYLQSFIKSSMLYLILMWALSPLLYSYLPP
                     KYVLMTSLMSTSYSDADIPYLLSPYLGLVGVCIVLKLRKHHEII"
     gene            complement(39676..40077)
                     /locus_tag="TV188_000703"
     CDS             complement(39676..40077)
                     /locus_tag="TV188_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534079.1"
                     /translation="MKLGKIKIGLLAIVASTLLISSLVIAERQIGYLQNFRITSSFGR
                     TKDYLVKSAAPYYVVNLDSRGRNREIVVRHYLANSNGQRRSDIDKTWTGDRGIYTQDT
                     KSGYLYALHLVRENWWDGATTISGSWSPDNW"
BASE COUNT        11551 a         9404 c         7976 g        11434 t
ORIGIN      
        1 ccttactcta ccaaggggtt gagtaaggtg tggactaaaa caagtgataa agtcgggtgt
       61 atagcataaa gcttaaactt ttcttaacct agaaaaataa ttttttgatc tcatgagacc
      121 acaagctcac ctcaagaagt aagaaggaca ttcactgatt gagctgctgc cctgtctggt
      181 aggacaacta aggaaagaac cttgattgtg gccgattctt gaatagtagc agcgctttgt
      241 gttatgatat gggcatgatt aaaaaagatt atcgccaact agtgcttcag cgcctagcca
      301 tgatgacccc agaggataag ctggaaaagg acttagctct attggcagca gtagttgcta
      361 gtagcagcta tcaagaggcg cagactcttg tgacctatct gcccttgcca cacgagtatc
      421 aaagccatct actgattgag cgagccttgc aggacggcaa gactatcctt gtgcccaaga
      481 ctcgttctcg tggagagatg gtgtttgtgg cttatgatcc ttgtgacttg atacagacgg
      541 cttttggtct tatggagcct aggtgtacca tagctgttgc taagtcggag attgatgcca
      601 ttcatgtgcc agggcttgtt tttcaccctg caggctatcg tataggctat ggtggtggct
      661 actatgatcg ttatttgagg gattatcagg gggctacctt tagcacgatt tatgcctgtc
      721 agtgggagga ttttgtggta gaggcacatg atattgctgt gaaggaggtg tattgccaat
      781 gagactgatg atcaaaaaat acccgataac actctttttc ttgggcttga ctggtttagt
      841 ttttttgata atgcagctgg tctatggcca gtttgctacg cacccttatg ctgttgttat
      901 atttggtggc atgaatggtc ttgttgtcag agcaatgcct gatcagcttt ggcgcttggt
      961 gacacctata gtggttcata ttggctttga gcattttttc attaatacct taacccttta
     1021 ttttgtcggg cggatggctg agaccatttg ggggtcaaga cagtttttgc tgctgtatgt
     1081 gtgttcaggg attatgggga atgcttttat catgtggctg acaccagata ccgtagcagc
     1141 aggtgcttcc acctctcttt ttggtctttt tccttcaagc ttataagtgc taggacaggt
     1201 gtatctttga tttaaacaaa aagcaacggt tttgctgctg ttgcttttta atgcttctag
     1261 gacggttgcc ccaactccta ttttgtctgc tgttgagtgc tttctagtgc tttacccagc
     1321 tttataatgt agtcagtgag gtcgtccttg acctgagggt gcttgagagc atagtcaagt
     1381 gaggtcttca taaagccaaa cttgtcccca acatcatacc gctctccctt aaactccctg
     1441 gcaaaaaccc gctgagtctt gttgagcttg tcaatcgcat cggtcagctg aacctcattg
     1501 ccagccccag gcgcctgatt ctccaatatg gcaaaaatct caggcgtcaa caaataacgt
     1561 ccaataatcg ctaagtcact aggtgcctca tcaggacttg gcttctcaac aaaggtctcc
     1621 acactataca agcccttaac agccttccct tgcggtgcaa tcacgccata attggaaacc
     1681 tcctcatgcg gaaccctcat cacagcaatc gttgaggcgt gtgtacagtc ataatcctcg
     1741 ataagctgct tggtcaaggg cttggcacta ggattggtaa tatccatgag gtcgtctcct
     1801 agcatgacca caaagggctc attgcccaca aaggccttgg cttggaggac agcgtcccct
     1861 agtcctctag ggtggctctg acgaatgaag tgcaggttga tggcagtggt ctcatcaacg
     1921 agcttgagca gctcggtttt gcccttggct tggagattgt attcgagctc gaagttggag
     1981 tcaaagtggt cttcgataga gcgtttggcc ttgccggtga cgacaagaat ctcctcgata
     2041 ccggccttta gggcttcctc gacgatgaat tgaatggttg gcttatcgac gattgggagc
     2101 atttccttgg ccagtgcctt agtggcaggc aggaagcggg tgcctaggcc ggcggctggg
     2161 ataatggctt ttctgacctt tgtcatgagt tcctccttga tttgtggttc cttatgtgtg
     2221 ccacttgttt tctgactagt ctcttccaaa gacatctctc gtgtaaacct tgtcaatgac
     2281 atctgctagg tcgtcctcaa agcgatttga cacaatgatt gtagactcgt ttttgaactg
     2341 ctctaaatcc tttacaactc tatagccaat gtcctcacca agcatgggtt cgtaaatgac
     2401 aatattaacc ccatagtcgt tgatgatatc aataatatct ttaatggcgc tttctcggaa
     2461 attatcagag ttgcttttca taatcaagcg gtaaaagcca atcgttaatg gtacaccagc
     2521 ctgcttttga ctagaggctc tgtctaatat ttgttcagcc aaataagatt ttcgtatctt
     2581 gttggattca acaatcgctg acatcaagga ctgggggatg cctctataat ttgccaacag
     2641 ctgcttgctg tcctttggca ggcaatagcc gccatatcca aaggaagggt tattgtaatg
     2701 gttaccaatg cgctgatcat gacagactcc ttcaatcacg cgctgagcat ctagaccctt
     2761 gctttcggaa taggtgtcta attcattaaa gtaagacacc cgcatagcca aaaaggtatt
     2821 cgcaaatagc ttgaccgcct cagcctcctg tgagcccata aataagaccg gagtatcctt
     2881 gcttttggct ccttccttta aaagaccagc aaaggcttta gcagcctgaa taacccttgg
     2941 tgagtcgtcc ttttcataag aaacaatgat tcgacttggg taaaggttat cgtataaggc
     3001 ttttgattct cttaaaaatt ctgggctaaa aataatacga tctgtctggt atttttccct
     3061 aacatgcttg ataaagccta gtggtatggt tgatttgata ataatggttg ctgacgcatt
     3121 taggtctagg acctgctcga tgacctcttc aacatgcctt gtgtcaaagt agttgcgttc
     3181 gctgtcataa tttgtcggag tagcaatgat aataaggtct gcattgctat aagcgcttgc
     3241 gccatcaagc gtcgctgtga gatttagcgg cgcatttttt aaatactcct caatatcagc
     3301 atccttgatt ggcgatatgc cttgattgat caatctcacc ttttcatcaa taatgtcaac
     3361 aacagtgacg tcattatgtt gtgccagtaa aatactcaag gataggccga catatcctga
     3421 gcctgctaca gaaattttca cttcattttt tcctttgata ccttagtaca gttagctact
     3481 gccggagctc aggtgccaca cctgaaggac catgatgacc tagccctcat accaaagctg
     3541 acgctcagcc tctggttcgt cttcacaggg ctacaagcta aaagctctta actcaagtac
     3601 aagtggacta gctttatttg atgagctgct taactcaaga tgctttgttc actcctagct
     3661 tagctccctt gtcagaacct aggtctagtt ggtttataat aattttttac gtgttcccca
     3721 gtcagcattt ctaatagtaa aaagagaata caatttcaag ggctgtagga caaacaaatg
     3781 cagcacccca taaaacggag ataacaagaa ggacagcggg tgcttaagca tgtaatgaat
     3841 gttccgacaa agagcaacaa tgaagataat caccagaaag gctaaaaccc tgagccaatc
     3901 aaattctctg acattgccta caaagaaatc caccacagaa taaacaagca tcataaacat
     3961 agacacctca agtatggtcc atagggctac aaaaggattg ttcatgattt tcttaacaga
     4021 aataatggac tctctaaaga aggacttgtt ccagcggttt tgctgcttca agtaagtaga
     4081 catcttgtca ggaacatctg taatacattt agcagtggat tgataaacag tctttcctaa
     4141 atcagttgca tagttggtca agcacctgtc atcaccgata cttacaggaa tacccaggaa
     4201 ggtctggttg atgtatctgt ctatattagg aacaaccacc tcgcgtctgt aaacgctaag
     4261 tgggcctgag caaacaagga tattacccgt aactgattgg gcagctcgtt caacgccaaa
     4321 agcattatca tagcgaatat ctgtcaagcg tgttaagaga ttggtttgtc tatttctgac
     4381 attaaggtga cccgtcgcag caaaaacagt tgggtcatta aaggtcttta acagctcctc
     4441 taaagcatca gggtagatat aagtatctga gtcaacggtc aaaaagacat cagcgtctga
     4501 tctttcaaag gcccaggcct gtgcatgacg ctttccttga tttttctctg accgatgaac
     4561 aatgacattg cttgataggt caccagtgtc acgcacatag tcttcaatgc gcttaatacc
     4621 tgtctcatca gcacttccat cgtcaacaac ataaatttct gctaggggat aggtttgctg
     4681 ctgaacactt tttaaggtct ctagcaatga ctcagcgtct tcgttataag agggaataat
     4741 ggctgcaacc ttatattgcc cagcccttcc cttaaatggc ttgtaaaaaa aagataagga
     4801 cattttgact aatagataag ctatcagcaa aaagccataa attgacaagc ttcctttagc
     4861 accaaagaga taaacattga cgtaaatcaa cagtacccaa aaaatactaa aggccacaac
     4921 agttatgagg ttttttaatg ttctcattgt gattggtttg atcctctctt gcgctttgta
     4981 ttttgccttt aaacgctaac cataatatac catctgtcac agcaagcaaa caaggtcatt
     5041 aatttaccat tctattaaag atagattaat cttagtgtca atacagcttt ttctaagatt
     5101 tgcctatgct caccaagtca tcaatcccct acaaaaaaca aatgatagcc tgagtctacc
     5161 tgtggctatc gctagcatgt gcctgataac aagcagctaa atggcccgtc caaaactaag
     5221 gcgctttgga cagccgcttt tcgctctctt ttttgacatc aaaaaagcag cccttatcag
     5281 gccacttcat attggtaaca aagcaattct ataaggagct ccttaaagga taagggcaag
     5341 agattacttt agagacttga tgatctcaat gcgagtgata accccctcat gcatatgatc
     5401 tactcttaag gcaacatcag aaaaagcaat agatgcccca atcgttgcag tctttccttc
     5461 ctcttccaaa tggcgcagca ttaaatcacg cattagctcg tttttgttaa taaccggcag
     5521 ctcgacacgc gctagcacat tagctatttt gaccttttga ctgccccgaa cgataatgct
     5581 tgaagtatca tcaaagcttg taaaaaggta ttttcgcgtc gcaaataaaa tagcaagagc
     5641 tatgacactc aacaaagaat ccttagcaga gccatgagcg acaacaattt gccgggcaat
     5701 cgcaaacaaa agcacctcaa taatggttcc tgaggtatgc ttactcagca ttttaatcag
     5761 ctcgacacca atagcaatac tcatggcctg gtttaaaaag ctctgtaaat aggtatcaat
     5821 gccacttttt atggtaaaaa tacctgtcaa gctcaaggcc aagcgccctg tcagcactag
     5881 taacgaaatc accaagatga tggaaataat aatctcaaca taatgagata gctcatacaa
     5941 tctaatctgc aaatattttc tcatagcaac tccttatcat tattatataa aaaatgccac
     6001 tatttgaaaa taaaaaaaga gcacacaccc gatatcgctt agggctgctg gattcctccc
     6061 ctgacccact tcacgcacaa gtgttgctcc acctttattg tagcatatat tgtaccctaa
     6121 aacaagtctt atttcaaaaa cgtctcacat ctggctcata aagcttaatt agctcaacag
     6181 caaaccaagc aaacgctatc aataaggcca gtccttaaag ctaagcccga ctagacttgt
     6241 gctataatgg tactaacaaa cctgagtgga gatgatatga aaaacaagct tagcctattc
     6301 ttgctggcag cacttactat agtcggtctc tcagcctgtg catggagatc caatcctctt
     6361 gctgacaagg agcagcagtt cggcctgact ggagcaagac gtcagcaggt gcttgatcag
     6421 atcgatcaac gttattatta ccagcagctt agtcaggcag aaaaggaaaa ttaccttctc
     6481 ttgtatgata gcctctcagc ctttcacgag gtgactagcc tagcaccagc ttctaagcat
     6541 agcttgatga caaccattga tgcctttatg atggataatc ctgccttttt ctggattacc
     6601 tcagccaact accgcttgga acgctcggat caggtggcct tcgttacctt tccattgcca
     6661 gagaaggtcg aacaaacata tcacaggctt caagccattg gagatgatat catcgctgac
     6721 atgccagcaa ccaatgacta tgagcgcgtg aggtattttt atgagtggat catcaagcaa
     6781 actgactaca atagagatgc ctttgaggca tatcaatcgg gtcatgaggc cttgatagcc
     6841 tctaatcaag acattcgcag tgtctttctt gatcatcttt ctgtctgcaa cggctatgca
     6901 caggcctttc agtttctttg ccaaaaggcc ggtattcctg tcgcctatat tcgagggtca
     6961 gtcacctttg atcgatcaca ggacgttttt actcatgctt ggaatactgt tcagattgca
     7021 ggcaagaact atgctgttga cacaaccttt ggagatcccg tctttgatca aaacgaatcc
     7081 attaaacaac tagaggttaa ttataacttt ttatgcttgc cagaccagct catgaagcag
     7141 tcgcatcaag ccagcaggga tattgtgatc aatcagacag aaaccttgac cgatgtctgg
     7201 acaattcctg agtgctcaga cgattctctg ctctatacta agctcaatca cagctacttt
     7261 actgcctttg atagaccaga cattctggcc agtcttgagc agcaattaag gactaatcag
     7321 ccacagacca gcttacaatt tgctaatcag gacctctaca accaaatggt aagtgatctt
     7381 gagcagcatt ctgacagcta ccatagcctg tttcaagctt attggcctaa tgctgctggc
     7441 tatttctaca gtctacaccc cagcaccttt agcattagca ttagcattat caatcagcaa
     7501 tagcctaata ccctgacaga caagtacaag cgcttatggc atggctctac cagccattaa
     7561 agagctgtgc taggctctca agggtctttt ttcttgctaa tcgctcaatg ggctaaatct
     7621 tactttcctt atcctgcttt ttctggtcac gcctttgccg gaaaaaggtc tgcatgagct
     7681 tggcacagtc atcagccaaa agacctacct caagctgtac acgatggttc aggcgctcat
     7741 cggttaagat ctgataaaga ctaccagcac cgccaaactt ttgattgctg gccccataga
     7801 ccacatgagg aattcgagct agcccaatgg ctccgctgca catgacacaa ggctcaatcg
     7861 tcacaaaaag agtcgtatcc aagagacgcc aattgccttc gtgcgcattg gcttcattaa
     7921 tggccatgat ctcagcatgc ataatcgcct gattgcgctc ctcgcgagca ttgtgaccac
     7981 gcccgataat gtgaccagcc ttcacaataa cgcagccaat cggtatctcg tcctttagca
     8041 gcgatttctc agcctccttg agggcttctc gcataaaata ctcttgctct tgtttggaat
     8101 agctcattga gatagactcc ccaaatccca agcccgatgt ggcagagcaa gatcaacagg
     8161 aatctgacca gcatagcctt gagcttgctg tcgcagcacc tccaaatgcc tcttaggatc
     8221 aatcccctct ggcggcagag gtggcatatg ggtcaagacc aagcgtttca ccttagcacg
     8281 gctggcaagc tgcccagcct cttttgaggt caaatgcgcc atatgatgtt cattgccttc
     8341 ataaaggtac acatctgcta aaaacacatc agcctccgca gcaaaatcag ccagctcttc
     8401 aaagtagcct gtgtctcctg taaagacaag cacctgccca gttgctcttt ccacaatacg
     8461 aaaagcatag cacacgaccg ggtgaaccgt cttaataaag gtaatgtcaa aaggtccaag
     8521 agcttcaacc ctatcaacct gataggcaat gccctttgag acacctggca aggttagttt
     8581 ggcaaactcg gcctcatctt cgtcatgacc gtaaataggt agtagccttg gcttgccaag
     8641 atgccttgga tagagctgat aataatgacg caaaacaccc aagtctgcca catgatctgg
     8701 atgataatgg ctaatgataa cagcgtctaa atccagcgga ttgatttctt tttctaattc
     8761 gttaagagaa cgactaccag catccatcaa taattgaaaa ccatcatgcc ctgtcacaag
     8821 ataggctgtc gtcccagcat cttgataggg ataggctccc caagagccaa gcgttgttaa
     8881 tttcatcaca aaaccttcct tcatgctttg ttcttattat aacaaaaaat agcagcaaaa
     8941 aataagtcct agtgcgcaag agctaggact tacaggctta gtatttagct gttggtgttt
     9001 aaaaagctgt ctttatagct aacagcaagc gccgttgcga tgactgcctt aatagtatct
     9061 cccgggataa agacaaggct agcaacgagc gatctagtga gcggcatgtc tgtataaacc
     9121 gctagccaaa tagtccccaa cagatccacc agcaggacac cagaaataaa gattgctaaa
     9181 aaagcaagag accgatacct tgctagccag ctgcggtaca agaatgcaaa aaccaatgga
     9241 acaaagagcc aggccaaaac atagccagcc gatggtccca ttaggactgg aacagttgtt
     9301 ctagagcctg aaaatactgg caagaacaga ccaatcacta gaaaaagcag gatagacagg
     9361 gttccttttt tcccacctaa aatcaagcca gcaagcatga cccctaagtt ttgcaaaaca
     9421 atcggcactg gaacaaagcc tagaggaatc gctggaataa gacctaaaat aatgattaag
     9481 gtggtcatca ttgctacctt cactaagtcc ttggttgaca acatatctca taactccttt
     9541 gaaaaataaa tatcctgatg cttatgatag gctgggttaa aagggctaaa acaaaaagga
     9601 cagctgccgc actcatattc ggaccttctc agcagttgtc ggcaatgacc acaaatcacc
     9661 ggataggtct ccttgtggtc tgtcggctca aaagcatgat cttgaagcgt gtcatgacaa
     9721 tgataacagg cataataagc ctgacatcga gcacacttca agccgacaat atccagcact
     9781 gtgtgataat gtacacagcg atactcctga tcaagcgcga taccaaaaca gttcctcatg
     9841 tcttatcctc ttattaaaag gataaagcat tcgttttatt ttgtcaacct atatttacta
     9901 atagggttac taatcgcata agaagaacac caaaaaagca taaagtagtc ccataggcag
     9961 ctgcttttta ccagtaccac acaaatagct atatgactat aaaggttggc ttaagaaggt
    10021 tcagatttaa ccgagtgtgg gaaaaagatt accaatctag ctgccaaaat acggggtctc
    10081 gtttgactat ttttccctat tgggatataa tgagaacaga aaaagggcag ttgctctaaa
    10141 caactaccct atgcagaacc gtttaagacg gtggcatatc tttaattatt aaaaaataat
    10201 cgtcgaccta ccaaagttca gacggttatt ttttattgtt taatatgacg attgcaacga
    10261 ctaagctgat taaggtaagt aagaaactac caaaagccag catgagttga agggcctcgt
    10321 aagtagacaa taaaacgctc ctttctgttg gattttgatg cattgcccat aggtatcacc
    10381 acctttcaga aatcagagcc accgccttag cttttctgta aagaacatta ttatatcata
    10441 atcacacaag aatccgtcaa atcttaaact aatcaggcgg cttttttatg ctctgactat
    10501 aggtctgaag agaagatgct agatgtctta ggtggctttc catttaaact acgaggtctt
    10561 ctttctcaca gagtatagcc ccctcttttt tcagctactg tttcggaggc aagctggcat
    10621 ttcgtctaaa ttgcttttgt ttttccctga gcattcgaaa aaatccttta tttctacctg
    10681 acatatcact aaaagagggt cctgtgaccc tcttttatag ctatctgtta gagagatatg
    10741 caattgttag tcttgttttt tcttcaagcc taggacacct gcgctagcaa tgacgctgag
    10801 agctgcaagg gtgaaaaatg ggtgatttgc ctcccccgta gctggtagcg tgcccttttg
    10861 agctgctgga gccgctgatt tgtttggtgc tgactgagga gctggtgcct ttggactagc
    10921 tggctgctct gaagattttg gtgcctgtgg agcaggggat tgctccggtg cctttggagt
    10981 ctctggttct tttggtgctt gtggttgctc ttttttctcc ggtgtttctg gagcctttgg
    11041 cacttctggc accttttgtg attccccttg ttgacctggc actccttgtg gcccagtatc
    11101 accttttgga ccttgttgac ctggtgcgcc ttgtgggccg gtgtcgcctt ttggtccttg
    11161 ttgacctggt gcgccttgtg ggccggtatc accctttggt ccttgaagtc cctgttcgcc
    11221 ttgtggccca gtgtcgcctt ttggtcctgg ttgacctggc tctccttgcg ggccagtatc
    11281 accttttggc ccttgttgac ctggtgcacc ttgtgggccg gtatcaccct ttggtccttg
    11341 aagtccctgt tcgccttgtg gcccagtatc accttttggc ccttgttggc ctggcgctcc
    11401 ttgaggaccg gtgtcgcctt ttggtcctgg gagacctggt tcaccttgtg ggccgatgtc
    11461 accctttgga ccttgttgac ctggctctcc ttgtggccca gtatcacctt ttggcccttg
    11521 ttggcctggt tttccttctg gtccctgtgg gcctattggt ccacgctcac caactggtcc
    11581 gcgttcccct cgaaggcctt gaggtcctgc gggacccatt ggaccttgag gtcctggtat
    11641 ccctaatgaa tctttctcat acaatttgta taattgctct gattggcctg tcgatttttt
    11701 taaaaattgc tccactcgcc atagatatct taaaacattt tctagcattc gaccattgtt
    11761 ataatgtgtc gaagtttccc agtcacttga gctaccagaa ccaggattaa gtatttcttt
    11821 ttttatgaac tgttgaaaga aatatccttg attatacata gaaggatatg taaagtcttc
    11881 tgcccttaca tcatttccaa tccctaagct agctatggtt gctagggcga caactgctga
    11941 gcagataccg tacttctgaa caagcctgat acttgttttc ttgtttctca tgtttatctc
    12001 cttttagttt agaaatgtta acgatttcta atcttttttc ttccaaagaa aatcttaaca
    12061 tgacgcttgc gggctgtgaa tatgttttgg ggaattcgct tccgtagttt cgtttttttc
    12121 taatcaaagg gtcaattgtc tgacgctagt gtcttttggc attggccttt agcttaggaa
    12181 gactgcctat gttagcaagc ttttcattag cttatccgtt ttgataaagg gtaagcgacg
    12241 aggataatct gactttgtct tttgcttttg ttagattttt taatgttttt ttgatgtctg
    12301 atgactttta aaaaaagcct tcttttgata ggcaagctta aaaggcctag gcaaaagccc
    12361 agacccttgc tgctattatc tgttattgtg gaaagctacc gctctttggc actgtcatgc
    12421 ttaaaaattg cgacttgagc tattgtaacc atagcgctca aggaaatcct gacgaaactc
    12481 taaaaggtta tcgtccaaga tagcttgacg cacctgcttc atgaggttta ctaagaagta
    12541 taggttatgg taactggtca agcgcatgcc aaaggtctca tcagccttta agagatgacg
    12601 caggtaagca cgtgtgtaat gctgacaggt gtagcagtca caatgatggt caagtggggt
    12661 aaagtcctct gcaaacttag catttttcac aacgagacgg ccctcgctgg tcatgcaggt
    12721 gccattgcga gcgatacggg ttggcaggac gcagtcaaac atgtcaaccc cacgaatcac
    12781 cccatcaatc aggctatcag gtgcacctac ccccatcagg tagcgtggct tattttcagg
    12841 taaaagtggc gttgtaaaat caaggacagc attcatctca gcatggctct caccaactgc
    12901 caagccaccg atagaatagc ccggaaaatc catgctcaca aggtccgcag cagattgacg
    12961 acgcaggtcc tcaaagccag ctccctgcac gataccaaag aggccttgat catgaggacg
    13021 gcggtgagcc ttcaagccac gctctgccca acgactggtg cgctcaatgg attttttcac
    13081 ataatcatag ggctggtaaa attgcgggca ctcatcaaag ctcatcataa tgtcagaccc
    13141 taggttattt tgaatggaga tcgctttctc tggtgataaa aacatctttg agccattcag
    13201 gtgattttta aaggtcaccc cctcctcagt gatgtttctg gagtctgcca aggaataaac
    13261 ctgaaagccg cctgagtctg tcagaattgc ctgatcccag ttcataaatt tgtgaaggcc
    13321 gcctgcacgc gcaatcagct catctcctgg tcgtagccat aggtgatagg tatttgacaa
    13381 aataatgcct gacccaatct ccttgagctc ctcaggagac tgtgtcttaa ccgtcgcctg
    13441 tgtccctacc ggcataaaca tgggcgtcgg aaaggtccca tgcggggtaa taatctcacc
    13501 gagacgagca cctgtatgct tttccttttt gatcaaacga taagtaatag ggtaattagt
    13561 cattgtttct tttttccttg ctatcaagat aaacagtctt gagcgttttg cataccactt
    13621 acaaagcact tagtcaagcg gtatgggctt gtttagagcc ctatcatttt atcaaaaaat
    13681 ctctgacttg tcatgccttc aaagagacaa gatcccgaag caatggcacg acagacgcat
    13741 gaaggagttt tagcaagaaa agaaagcttt ctgtcgttca atgttcagct atttcaagta
    13801 tatgtcttat cttttataaa ctttactaca gaaaaatcgt tgaaaatgtt tgctttactc
    13861 tatactatca ttcagaaata gctgtttcgc gcgtttgtcg tgagcaagga cggtatgggt
    13921 atcactggct cctagaatat ggtataatgt accaaaggag ttgtacgatg tcaattagag
    13981 aaataaaacg tgaagctaga cagactttaa agggactaaa ggggaaatac ctcttatttt
    14041 tagtaccgat aatcttatct attttttact caggaattga ggttcatcag acctatgtga
    14101 ccactcaggg gattgaggta tcagtcgggg caagctactt tcctttgatt gttctgataa
    14161 tgctgacggt ctttacctta tcagcagcct ataccatgct agatgttatc cgctactatc
    14221 gtcgtgaggt ctctttttca gaggcaacga tagctttttc tggaaacttg tttggcaagg
    14281 tccttgtttt gttgatcatc aaagggctcc tatttatcct atggtctttg atttggattg
    14341 ttggcttggt tattctaacg attagctctg cggcattact gacaagctac aatactggtg
    14401 ctgctgtgat gactccaatc atctttatgg ttattggttt tgtgattttt attatcgggc
    14461 ttattgttta tatgaatcgt tattgtgctt acagcatggc tgagtacatt ctctatgaca
    14521 aggtcaagga aggcacctat atgggtgcta ttacggcaat cgaagagagc aaggacatga
    14581 tctcaggcta taaaggaaag tattttttac tacaccttag ctttattggc tggtttatcc
    14641 tagtaatctt gtcttttggc ttgatctata tctacgtact gccttattac accactgctg
    14701 atgtgacctt ttaccaccat ttaaagcaca ttcacgatga aacagagctg ccgatagatg
    14761 ctgaaaggct tactatcaca ggttcaaaag aagccccatc tgctattagc tagccttaac
    14821 gatatgcctc tatgtctctc atgaccttgt tcagagtaga catagaggtt ttttgcatga
    14881 cctttgataa cttttttata gtaaaaaaga ggagcccatc agttgcctat ccaaagctag
    14941 atgacacatc taacggttgg aaggcttgct tacaggccct cttttagcaa tgttagccca
    15001 agactatcct aaagctgctg aaaagctcct cggtctaagg cataggcagt cgtccaatgg
    15061 ctctcacgat agtaaataaa gagctggcta tctaatagct catcaattga ggctgctgtt
    15121 ggcagacctg ctaggtcaat gaaataatcc cctggaagaa gctgttgtag cttttccatt
    15181 aaggcggtat taacagcggt ctttgctgct ggtaattgac tagagattga taagccttca
    15241 aaggtcttta aatctatgtt ttctgactct aaagctgatt ttaaggctga tttgatcaag
    15301 tctaggctgt attcagcatc taaggcttca tcgcctgatg agaggctatt catcgccaat
    15361 acatacaaag ggcctgctgc cttatcctga taggtaatga caagttgatg gttcagcaaa
    15421 tcagctaagt catcataagt accagtgttc tcaagagtaa tgtaataagt ccctgtgagc
    15481 cctaagtcct tgattgtctc taaaatcttg ccttggattg cttgattttt ttcagttgtt
    15541 gccgctgtta gaccactatt tgtaatagca aagctctcaa tctctttggt agctgtattg
    15601 gtctctttta gaatggttag aatactatct ttaagcgcta gaatatcatt tctaaccggt
    15661 gcttcaatag ggctagagat gtcttcaaag aaacgataag cagaaccgct gacaaattta
    15721 ttggcctgtc cgctgctttt tccataggtg tctaaggcag ttattctaac aaatcgacct
    15781 gttgttggtg taaagctgac tgtttttagc tcagtatttt gcttccaatc agtgctatcg
    15841 acaaccgttg tccagacctt accgtctgag ctgatgtcga cctttgcaga atggatcata
    15901 ccattaacac ctcctgggag ataggcaata gcagagaagt ttttatcgtc cttaaactca
    15961 acagtatatg acttgtcctc agtaacctga ttaaataagg tatgccattg ggtggccata
    16021 tctctaccat ctaccatatg cttgccagac ctgcctgatt gctcattagc ataggtcacc
    16081 gcctgaatat catcaattga gatgtagtgc attgtaggat cagtgctgtc tgcggtaaag
    16141 gtataggtaa cgctgtcact tgctagactg gtgccatgag cccgatagcg agcaagaact
    16201 gtgacagtgt cattgaagcg ctctgtgcca tcataagcct gccaagactg gccattatcc
    16261 agactgacct ccaaatgttc aatagcacca atcaagcgat tttccaagtc attgccataa
    16321 aggctgctgt tggtcggtgc tgctgccttt gtcaggttaa tcctgtaggt agcagatacc
    16381 gcgtcaaagc caactaaaat accgtcctct atattaagct tggccaaaag gtcatcacta
    16441 aaaacgataa ccttgtcctt ggtttcaagc catgttttcc cattatcaat agaatagcgg
    16501 actgtcaaat ctgtatcctg ataattctca tgcaaacgaa gggtcttgtc atcaaagcta
    16561 aagcttgctg tttcgattgg attgcccgtt aggatatagt tggcgataat tctaacctca
    16621 ttagattgga gcacttcctt atcagttgct gttttggctg cgattagagc gttatagctc
    16681 agtaaatcta gctcagcctt agctgcttga tcgctgatat taggcgtgat acgcttgata
    16741 gcctctacca tgacctgtgg atagtaggtg taagctgcaa tgacacgctt tcctaagtcc
    16801 agccaatcct gatctgtttt ttggccattt tttgcatagg cctctatcaa gccatcgtaa
    16861 gtatctagat taagctctag tacatctaaa gccttgctgt aggcctcaat ctgttgatca
    16921 ctgccagcct cgtagacatt agcgatgaga ttataataaa gcgattcctt gaacttatcg
    16981 tattggttta aggctgcttg cgccagcagc atatagctag cgtttttatg aatgtcattg
    17041 taggatttta ggccccagcc aagcaagagc ctagcctctg ttgctgttgt ggttccccaa
    17101 cgagaataag agattgccca gcgattacca taaacattgt ctctaatatc ccaaatcccg
    17161 ttgccctgat catcttgacg gtaaaccaaa taagcctcgt ggtcattttg gtaaatattg
    17221 accgctggaa taccaaagac ctcattgact gctacaccta aatttgataa tccccagcaa
    17281 acagcccctt tttccatcag catccagatc cggtgacggt tgtcataagt aacattaaag
    17341 gcatcgtcat tgagggtgcc aacgagctga tatttttctg tccattgagc ttgattgtca
    17401 gcgctgcgca tgtctgcgcc accgtagccg atgtttttgt atttcgtata agagtagcca
    17461 ctggtatagc tagcaacctt atctccatat ttttgttcgg cgtaatgatg cagccagaga
    17521 atttcctcat catctatttt ggcgtccata acagcacgca ccaactccat attgtagttg
    17581 gcgaattctt ctttcctcaa gaattcgttg tctcgataca attctttaaa ggcttgatat
    17641 ttcagcaccg ggtcagaagc aaggtaggtg ccaccatagt taaccacaaa ggatttgatc
    17701 tccttgcagt aggcaacagc agttgccagc atcatttttt tgtagacata gccatttccc
    17761 ttgtcctcca aatctgcctt attagtagca taaaggtctc ctaaggcgtt caaggttttt
    17821 agggtagagc cgttaaacat cgagcctgcc tctaaaaaca gtgacagagc gtcctcatct
    17881 gacaatagcc aatcaagagc gaccttgacc ttttcatttt tcttgacagc agattgaatg
    17941 gtgtggtagc cgacacgatt gacaaattcg cgctcaagca ctaatgccaa attgtctgga
    18001 ttatcataat tatctgtgac actattcttg ctgagaaggg catcatactc ttcagttgtc
    18061 tttagcctgt cataagacac ctcgcttgat aaatcataat ctgtcttgag caacctgaga
    18121 tccgcataaa cagagtgatc attaccgtta ttttttagtg aatttgcaat tagctttaca
    18181 tatttagcac ctgtaatatc tagatcaaca taaacagcct cactggttcc ggttactgta
    18241 ccagttgtca ccaggctttc ccaacttttt ccgtccttag acttatagat gttaaagcta
    18301 acaccatcgt ccttaccacg tctactatag tcaactccta ggtaggctga tagacgcgtg
    18361 tattcattgg agtattgttc aacatcataa taaagctgtg aaggagcatg cactgcaatt
    18421 cccttatcaa atgcaagcac ctcgccatca actactagag taatggtgcc accggcaggg
    18481 tttttgtcct gtaaaaagct gccatgccca accttggacg ggttgacacg tgtctcatct
    18541 gataagtaga tatagtcctt agcttcagtc ttattggtgg tctctactgc ttgtgatact
    18601 tctgtctgct cctgctttgt ggtctcttcg gcagaagctt cggtagcttg ctctgctgcg
    18661 gctacttgac tcttagagtc agttgtttct gtagtggcag tacctattac tactggcagc
    18721 gtttctgagg agccctcagc tgctgtgtct tgcgcagcgg ttgctgattg gtcagctgct
    18781 tgttgatcaa ccgcttcttg tgcttctaac gtggttgcta tggctgcact agctgttact
    18841 tgctgctcat cagcagaaac agttgtcagc cctagtgtta aaaataaggt tgcaaccaac
    18901 acagaggctg cacctgtttt aaaggtttta atggcaaagc gctgcttacc atcagtataa
    18961 ggtttgaaca tggtgtcttc tcctttaaaa ataagatatt taagcaaaat aaagactgac
    19021 caccaaccac tacagttgat aatcagtcca acaaagatat cgtactatag gaaattaatt
    19081 aaagggggaa aatcatcgcc tacagttaat ttgattcttt gcgtcttgac acaatagcaa
    19141 gctggcctgc acaagcaata actgcaagag ctgctgctgt aaagaatgga ttagctgtat
    19201 cagcagttgc cggaagcact tgctgcttat cagctgcttt cttgtcctcc ttcttagctt
    19261 caggcttaga ttctggttta ggctctggct taacctcagg atctgatggt tttactggat
    19321 ccgctgggtc gattggatcg accgggtcta ccggatccac tgggtctacc ggatccactg
    19381 ggtctactgg gtctactgga tccactgggt ctaccggatc cactgggtct accggatcta
    19441 ctgggtctac cggatccact gggtctactg gatctactgg atcgaccggt ttagcaacca
    19501 aggctgcctt ggcatctgag agggatttct tagcatttaa caccttaacc aagctgttag
    19561 taatagctgt cggttctgtc tcctgagcat aagctgtctc acccgctgct gcgacctcct
    19621 tagccttagc tagctggtct gtataggctt gagcagaagc tgctgtatat ggagataggt
    19681 ctagattttc tccgataaga gcatttaatt ggtctaaagc agaacgcaat tttgcctttc
    19741 cttcttcggc aatcgcagcc tttaccttta aaatagtatc aacaactgaa tttgtttctg
    19801 tagtgtagcg ctctagctca taaagggaaa tgtcttttct ctctttatcc ttgttaacag
    19861 ttctatagaa ggtacctgct gcttcaatgg ccttattgta caattccttc aaagactctg
    19921 atgtcaaagc aagatttgga ttttctcggt aaagctctaa cagcttagcc aaggcttgat
    19981 ctaaggcttc atgcgctaca gcagtcttaa gcgtcgtaag agcttgcgtt aaatcagtcg
    20041 cagccttatc aacatctcct tgtgaaggac caaatgaatt ttgaagctta gctgccgctg
    20101 caagcttttg cacaagaccg tcatacgctt ctttaggata ctctttgcca tctgttataa
    20161 aaggtgtagc ttgattaata gcttcattta aagcattaag attaacaaga ctagtaatag
    20221 cggaatcaat agtagtaaca gattgatcta ctgtattttg atcagggtca ctgtttaaat
    20281 aggtcttacc aatagtaacc gctgattgca aggcttgcag tgattcatca gaatacgttc
    20341 cttcaggctg gctgagtttt agcttagcct cctctaacga cttccttaac tcagttttat
    20401 tgctgttgga attttttagt ttaaatgtga agagcttttt ggtatcattt ttcccataga
    20461 atacccaagc tttaatagta taagatcccc ccggtacagc atatgtaggc gaagctaaca
    20521 tttcatcagt taaaaaggaa gtacccgcag cattgtaaaa gtcaaaccat atttttactc
    20581 caggggtatc aattcctctt gaaccatctc cattcgaaat aaagtcaaaa gtatctccat
    20641 cattaacagt cccattacta cctttacgag taaccgtaat ttgactcata agatctgaga
    20701 tagtaattgg ttctcctaat tcaactgtat attcttgtgg aatatctatg tgccagttca
    20761 gatgttgacc tgtcccatta ttttcaaatg cactagcagt agtcgtttcc gcccctactg
    20821 ttaaagcgct atcaatatta tccgacaagg caaccaatcc tgtgctgaaa actaatccaa
    20881 caagaccaca gcccttaaga caccgtttcg tgaatttctt cattcttctt tttccttttc
    20941 tagagcccta gcaggctcga acaatagcaa tatgtgtcat agggcagctg ctatcactag
    21001 tagctgccac tttgatatta gcctgattgt gacactcaaa tatcacttat aatttacaaa
    21061 aaattttaag aaaagtcaat atacaaacgg tttttgttaa attttttaaa aatataacaa
    21121 aaaacaagca cgccaatctg gtctataaca gtttttattg tcaatagtga tcgctaaagg
    21181 gtttttcagc caacaaaaaa agagtgaatc cctaactctc tcttctagac tttgtgccat
    21241 atcatcagct acacgaacag ccaagatcaa aaaggccagc tctcaatagt ctgtgtcctt
    21301 accctgcttc gtctgacagc tagggcaaac accataggct ataactggaa tacgggtgac
    21361 cttatagcct gtttgctggt gtgcttcctt agcgatatcc atcacatcta cgtccataaa
    21421 atcagcgatt gtcccgcaaa cctcacaaac cacattgaca tgctgatgtc ccataaagtc
    21481 ataataggtc gtcaaatcat tactaatttt cagctcggat acaaagccct catcaacgag
    21541 aaccttcaaa ttattataca ccgtagcaag gctcatatta gggtattgag gctgtaaatc
    21601 acgatagatt ttatctgcgc tggggtgctc agtggactga atcatgtaag aaatgatcgc
    21661 cttacgcgtc tcggtaatac gaatatgctt gtcacgtaga tgctctagga cattttcata
    21721 ggcatttaga gcttgctgat gtgaatgaat gtccaagctt acaacctcct ccttttgtaa
    21781 ctatggcact aactagcagg aatcttgatc ctgcttgctg attagccgta aatagtcaat
    21841 cttgatacag cgattcataa caatgtcagc tttgcctgct gatcgcaaaa gctcctcagc
    21901 ttcttggcta tacaagccaa gctgtgccca aaagacctga ccctgacaag ctaaaaagtc
    21961 ctgagcaacc tgaggcaaat actcacttcg tcgaaagaca ttggcaatat ctaccttaaa
    22021 aggaatagcc gcaaggctag cataaacgac ctctcctaaa acagactgac ctgccagcct
    22081 aggattgaca gggacaatcc gatagccctt agcctgcata aacctagcca catcataagc
    22141 agcagtggtt tgacgatcag ataagccaac cactgcaatg gtcttggaag attcaagata
    22201 agaggtgata gtctcatcag agggattttg aaatgtatca atcatcattt acttcctttt
    22261 tatcaagcac acccaatagc aaatcaacaa caggaaaaga caatcgctgc cggtatgaca
    22321 tagccaacca tctggctacc aagctcaagg aaaaccctcc ttagcatgac atgccctgct
    22381 gtttttttct cttcattata gcataagttt ttaaaatgcg gaacacaagg aataacagca
    22441 gccacaccaa gcaggctgcc acttaacacc actgctaatc tagtctactt ggcctcatac
    22501 cagctcttgc cggcactttc gtctacacgc agcggaactg ccaggctgac agctgattcc
    22561 atcgtttctt tgaccagcgc tttaacagcc gctagctcat gattaggcac ctcaagcaca
    22621 atctcatcat gcacctgaag cagcattttg gtctcaaagc caccagctac tagggcttgg
    22681 tcaagattta tcatcgcaat tttgagaata tcggctgcac tgccttgaat gggcgaatta
    22741 atggctgtac gctctgcaaa ggagcgaacg ttgaactgac gagaattgat atctggcaat
    22801 tgacgacggc gcttaaagag cgtctcaaca tagcccttat ccttggcttc acgcacaacc
    22861 ctttccatgt aagccttgat accagggtag cgctcaaagt aggtgtcaat ataagccttg
    22921 gcctgttttc ttggaattcc aaggttatta gacaagccaa agtcagaaat cccatacaca
    22981 atgccaaagt taacagcctt agcattccga cgatcattgg cagtgacgtc ctctggcttt
    23041 tcaatgccaa agacacgcat tgccgttgag gtatggatat ccgctccctc cttaaaagca
    23101 gcaatcaaat gctcatctcc tgaaatatgt gctaaaacac gcaattcaat ttgcgaataa
    23161 tccgagctaa gcaaaacagc atcatcatga gatggagtaa aggccttacg aatcaagcgc
    23221 ccctgctcca gacgaatcgg gatattttgc aggttaggat caacactgga aagtcggcct
    23281 gtctgggtta aatcctgtaa atagcgggtg tggatcctgc catcagccat gatgtaatcc
    23341 tgcagtccaa tcacataggt tgattgcagc ttagtaattt gacgatagtc caagatctta
    23401 gccacgattg gcgcaattgg cgctaagcgc tccaagacat caacagccgt tgaatagcct
    23461 gtcttggttt tctttgtcaa atgaagaggg agctgcattt tctcaaagag tatcactcct
    23521 agctgcttgg gagaattaat attaaagacc tcaccagcca tttcatagat ttcctgtgtc
    23581 agttcctcaa tgaccacctt attttgctct gccatttcct gcaggctatc ttgattgaca
    23641 gcaatgcctt cgatttccat tttcgcaagg acattggcaa gcggcagttc aatgtcagtg
    23701 tagagatcag cctgctcatg ctctgccagc ttatcaagca tgactggtct actatccagc
    23761 aagacctgaa ccttacgcgc cagatgtcct aacaaaacag ccttgtcagg cacagcacgc
    23821 ttgaccccct taccatagac aacctcatct gtatccagtg atatagtggt ataaagacgt
    23881 gccagagtag ccatctcatt gtcctctaca gttgacaaga ggtaattagc taagcgggca
    23941 tcatagctgg cagccggcaa atcaagcccc agatgactaa gcagaacctt actgcgctta
    24001 aaatcatagg tagcaatcgg ctgctcaaga acctttttaa agagctttgt agtgaggaga
    24061 ctaatatctg ctgaagcata aatctggcct tggttgcccc aagcaaagcc aatcagctcc
    24121 tcgcggtgat aattatccct caaagcttca aaataaaaca ccgtatcgtc tgaaaacatg
    24181 tccgctctta tgtcagtaac ttcctgataa gcaatctcag ctaccggctc ctgtggcaac
    24241 tgactagcta aggcattttt tagttgaaca aaatccatct catcataaaa ttgtgacaag
    24301 cgatctagat ctggaccctg atagacaata tcctccaatc caatcgtaat cggagcgcta
    24361 gtgttgatag tagcaagtgt ctttgagagg aaggcctgct ccttatcatg aagcaggttt
    24421 tccttcattt ttgaaggctt gaagctatca atatgctcgt aaatcccctc caagcttcca
    24481 tattcgtgca ggagctttag acctgttttt tccccaattt tggtcactcc tggaatatta
    24541 tcagacttgt ctcccatgag cgctttcaag tcaatgaatt gctctggcgt aagccccatt
    24601 ttgtccataa ggtaggctgg ggtaaactct tcaaattcag caactccttt tttagaaatc
    24661 tcaacaacgg tatttgcatc tgtcagctga atcaaatcct tgtcaccact gacaatagtc
    24721 acatcaaaag gaatctctgt acgctctgcc attttatcaa gcgttccgat aatatcgtct
    24781 gcctcgtaat gctctagctc ataaaaggca ataccaagcg ctcccagcat atcacgaata
    24841 taaggaaact gctcccgaaa ttcatcaggg gtcttggcac gtcctgcctt gtaatcagca
    24901 aaaagctctg tccgaaaggt tgttttaccc gcgtcaaagg ccaccaagac atgcgtcggc
    24961 tgaacacgct tcatcatgtg gtctagcatc aaatgaaagc cataaatcgc attagtgtga
    25021 agaccgctgt gatttttaaa gcggtcaatc tggttataga gggcaaaaaa ggcacgaaag
    25081 gccactgagg agccatcaat caaaagtaat ttattcttgt tttccatgcc tttattatac
    25141 cacacagtga cctgctttgc tctgaccagc tacgcttttt gcaagcacta gcaggtaaag
    25201 cagcataccc gtagcttgat caaaagatcc aagctgcttg aaggaagata aatgactgct
    25261 tttgctttat catcaagaca tttctaccaa aaaagagact gagataaaaa gagtgacact
    25321 ttagagagtc ttaactaata tcctttgtta tctaattcat taacaaacga acaggcctag
    25381 ttttcaaaac ctcagaaaac taaacctgtt catttgttct atttgaagtc agactttgtc
    25441 tcaatctcca aattgatgac atcatctgct atgactttcc taagctgata tggacggaaa
    25501 gccttctgca aaatccatga ttagtctagg ctacatttga gcgagcggcc ttatgactga
    25561 gtccatttgg ccaccttatc agcatggcta gccacccatt tcttggctgc ggcttctggt
    25621 gtcatgccct gattgatgtc aagcataaca gcctccatat cctctttttc ccaatggaag
    25681 tgatcaacaa tcctatgaac agctggcagg tcggccttta agccccgacg tgcaatggta
    25741 ttgatatttt cctttgagcc aaaggttttc tttggatctg ccaggtattt caaatcgtac
    25801 ttagcaaaca tccaatgagg agaccaagcc gtcacaacga tcggctcctt tttcttgacc
    25861 gcctgatcaa gtgaggtggt catagcacct gtcgaagcag caacgagctc ccaatctgcc
    25921 aagttggaat aggccttttg cgtcttatca gcagcagtca taataccagc tcccggttca
    25981 atcccaataa tctgttgatt ggcttgatcc gaaagctcct ctatgctgtt cacatcgctc
    26041 atataggctg gcacagcgag tcctagcttt gttcccttca gattaggacc aagattatcc
    26101 agcttatcct gatacttttg gtactgctgc tgatgggtca ctggtaacca ggcacttgtt
    26161 gaaaagtctg catcgccatt tgcgatggtt tgccacatca cagcattatc cagtggtgtc
    26221 aaggttacct gataaccctc atctcttaag acctgagcga taacatgggt agaagccacc
    26281 tcagaatccc actgcacata agcaatggtc accttctgcc ccttgtctgc tgagcttgat
    26341 aacatcgcag caaagccacg ccccaaagct gacaacaaaa agacagctaa agcagctaga
    26401 ccaagccatt tcttggtttt tccagtctgc gttctttctt gcggcttacc gttaaaatgc
    26461 tgagtcatac gatccaaaat aatcgccaag ataacaaggg ccaaaccact aacaaagcca
    26521 cgcccaatat cagcatgctg caaggccgat aggacctcac gtccaagacc tggagcacca
    26581 atcattgagc ctgtcacaac cattgatagg gccaacatca tggtctgatt aacacctgcc
    26641 atcatcgtat gctttgccaa gggtaattcg accttcagta atttttgttt aggggttgac
    26701 ccaaaggcat ctgaagcttc aaccaattct gtcggaatat gacgaagcgc taaattggta
    26761 aaacgaacag tcggcggcaa ggcaaagata accgacgcaa agacgccagg gaccatacca
    26821 atgccaaaaa aggcgacagc cggaatcaaa taaacaaagg ctggcatggt ctgcataagg
    26881 tccagcattg gattaatcac ctggtgaaca atcttatttt tagccatcca aatgcccaag
    26941 ggaataccaa gcaagacaga gatgaggctt gctaccaaaa ccagcgtaaa ggtattgatc
    27001 agctctgccc acaggccttg gttatagaca aataacaggc ccaggagggt aaagatcggc
    27061 aaaggccatt tttttcttgc caagaaaaac atcgcacagg taaccaatag cataaacagt
    27121 aacggattga taaacaaaag ggtctgcgtg atccaatcca tcaaagcatt gcccacaagc
    27181 tgcagcagat caaagaagcc tgaaaaggtt tttgtcagcc actcagttag ttgctcaacc
    27241 agctgtgcca ctggtagagt tgtttgtaat aggttttcca aaatacagtc tctccattct
    27301 aattaaggtc gtcatctgga atattagcca aggcttcaag gacacgccca cgaataataa
    27361 cccctaacaa gcggtgctgc tcatctgtca ctgcaattgg cgcagaagag tcataaatca
    27421 agggcaaaat atccgtaata acagtatcct ttgagaccgt tctgacatta cgatcaataa
    27481 cctctgacaa ggggagcttt ttctgacgtg cttcaatcgc tccgtctgct gttaggcttc
    27541 ctattagctg acgacgacga ttggttgcca tgagcataga cacctcctca ttgtgcatac
    27601 gattcaaagc cacctgcgga ccgtccagat caaccgttgt tgtgataggc ttaatcataa
    27661 tatgctgagc agtcagcacc tttgagcggt caacgtcctc tacaaattca cgaacaaaat
    27721 cattagccgg attggttaga atatcctcac ccgtcccaat ctgcatgatc tgaccgtcct
    27781 tcatcaaggc aatacgatca ccaatacgca gagcctcatt caagtcgtga ctgataaaaa
    27841 taatggtctg cttcatcgtc tcctgtaatt ctagcagctc atcttgcatg tcacgacgaa
    27901 tcaagggatc taaggcagaa aaagcctcgt ccatcagcaa aatcttaggg ctgtttgcca
    27961 aggcacgcgc caagccaaca cgctgctgca tgccaccaga caattgatca gggtattggt
    28021 ccctgacctc aagaagccct gactgatcaa gcgcacgctt tgcaatctct cgacgctcct
    28081 gctttggtac cccacgcagc tccaagccaa actctgtgtt ttccaaaatc gtcttgtgtg
    28141 gaaaaagagc aaagctttga aaaaccatat tcatatcatg cctgcgaact tctctgagct
    28201 gatccacaga cagtttagaa atatcccttc cctctaataa aatagagcct gctgagggct
    28261 caattaatcg attaagcata cgaacaagcg ttgatttgcc gctgcctgaa aggcccatga
    28321 tcacaaaaat ctcgccttcc tgaacctcaa agctggcatc atagaccccg acagtaactc
    28381 ctgtcttttt aaaaatagcg ctcttacttt taccagcctt gatcatttca agagctgctt
    28441 tttgtttttt gccaaacaat ttactcaaat gcctgacctc taaaatagtt cccattcttt
    28501 tcctctcttg ttctcttcct cgattaaagc taaattagct taatagattt ctaaaagtgc
    28561 caccacaatt ttaaaataat gaggtcactt tttgcttaaa aaaagagtct gcctaaacag
    28621 aacacattaa ttatataata tatggtcact ttttgtcaag ctggacgctt gctacccaag
    28681 tatcaggatc gtcctaagca gtgatatcac tagtcaacca agcacttaac agccctgaac
    28741 agaccacagc aagcaggcct ttctgacact tagcgccttg agagcttacc cagcagcctc
    28801 ctctagctga cttgattgac ctatctgact cttgtcctgc aaccaaacca atgcttagac
    28861 tgccaagcaa gctcccaata gcaataagat ctgctaagca aagcgttagc ttgctttgac
    28921 catagctgct agtcatgtct aatagcactc tagataaatc aaaagcccca cctagcaagg
    28981 ctagatgagg caaaataggt ttagagaagg gctttaaact gaatatttga gtcttccaag
    29041 aagcagtcgt caaagccacg tgggtgatga tactcgatgc gatcctgatc ctgtggatag
    29101 gtgtatttgc caccaacctc ccaaatgaat ggatggaatt ggtattgcaa gcgctcctta
    29161 cgcatcttcc aaagctctag gatttcatca gttgaggcca tgaagtttga ccagatatca
    29221 tagtgaaccg gaatgacaac cttggcgcgg agattttctg ccatacgaag taggtcaaca
    29281 gaggtcatct tatcctgaat accgattgga ttttcaccat aattgttcaa gacaacatca
    29341 atatcgtagt cacgtccatg cttagcaaaa tagtttgaga agtgggagtc tgcaccatga
    29401 tagatggttc ctcctggtgt ttcaaaaatg tagttaacgg ttttgcgagc taactcttcg
    29461 tcagtcactg gaagtcctgc tagctcgcca ccattttcct cagcgccagc aactggtaag
    29521 gtaacgatac aggtacggtc aaaggattca acagcagtaa ccttgatatc cttgaatgca
    29581 aagctatcgc ctggttttac cacgatgata cgatcctttg gaacacccca gctctcccaa
    29641 atcttgccgc actcataagg gccaacaaat ttgacatggt caagctttgg attgttgata
    29701 atggctgctg cagtattgat atcaatgtgg tcactatgat aatgagacac caagtaatag
    29761 tctaactcat taatcataaa gggatcaata accattggct gagctcttag atttggttgt
    29821 agcttgcgaa cccctgccat attggccatt tggtgaccac gaaccatgtc ttttactttt
    29881 ttagttgcct ttccacgatt ggaccatagg tccatgacaa cattggcacc acccggtgtt
    29941 ttgatccaga taccgcagtt acctagccac cacatagaga aatttccttc aggcactacc
    30001 tcttcttcaa tttcttcgtt tagccaggtt ccccattctg ggaaggtgct aagaatccat
    30061 gattcacgag ttatatcttg tactttagcc attatgtttc ctccaaaatg aatttttatc
    30121 tatactctaa gtatagacct tctttattct cataaaaaga ccaagtgtca cacactcttg
    30181 tgttcaaaac tggactgaat tttggctcaa aataaactaa aagccccagc cttctcctaa
    30241 accaatagac agctgagggg tccttatcaa taggcaagct agtagcttac aataattcgt
    30301 gatgaatgag cttttcaatt tttgttttca aggcatagcg gtcagcatcg tccttaacaa
    30361 tggtctcgat cgccttttct agctcaaggg aaaaacgaga gctatcactc aagcgcccct
    30421 gctttgaaaa acggatcaat ctaataatgt catcatcgct caaaatagga ttgacaatca
    30481 gtacgggaac aagagcctcc agtgcgtctg ttgttgatac cacaatgtca acagacatca
    30541 aatcaaagac actctggtat tgctctgttg taaagacagc ctcgatttga caattgggca
    30601 aataacgctg gcactgcttc aacagcagct tttgaatccc aatgccatca tctgaaacga
    30661 taacaagctt ggtcttgtcc cagtcagcat gactatggcg cagctctcct cccagatgaa
    30721 tcgttagata agccacgtca tcatctgtta gacggatctg ccaagcctgc tctaggatta
    30781 cagcacagga ttgagccata gcaaagagct cctcgtattt ttccttaata tggtctgtta
    30841 aaggattgat cgaaaaaatc ccataggcct ttcgataaac aagggccttg caatgcctgg
    30901 tcagctgtct aagcaagtcc tttttgtggg taaaatgcag ctgatagcgc agctccagct
    30961 gatcgataaa atcaccaata gtggctcgca tctgctcata atcctgactt tcaacatggt
    31021 gatcctgatc ttttctaaag gatagcatca gcatggctat catgcctacc tcaatgtcat
    31081 ctaaatgcag cttgaaattg tggtaaagct cactagccaa tgccttagca atctggtatt
    31141 ccttgcgctt ccaaatcagg ttaaaatccc ttttaagcgc tgttttagtt tccgaatgca
    31201 attgcatgtt gcgatagcta agcaggataa aaggaagaat ttgcagcata aactgactat
    31261 cctgaatatt aattgttttg cctaggctag cctgagacaa aaagaggtat tcgtgaaaat
    31321 aatccaaaac ctcctttgaa aaataagctg acaagccttg tgtctcagaa agcttatgat
    31381 caaaaagctc aataaagctg ctattgcctc cctgataaac acctgccaat accttgtaaa
    31441 ggtactgaat caaagccata gggtgacagt caaagtaata gcccttggcc ttggtggcat
    31501 gcagctgaat cttattgtta tagctagaca attcctctct cagttcagca aggtcattta
    31561 agatggtatt tctggaaaca tcattaatca tcatgagctt atccagtgtc acccgctctg
    31621 ttgccactgc aatataaatc gctgataagc tcctgcgctc atcacccttc atgacatagt
    31681 gataatctgc cacttcattg aggagctgtt ggcaggcagc cttttgctca ctatttagca
    31741 agatgccaac ccgaggatag gagacaattt gagcaacatg gctgggcagc gcttcgttaa
    31801 ttttatccaa atgataatag attttgcgcc gcgactgacc caaggcagct gaaatcgcca
    31861 tgactgtctc agcctccttc aatcgaatca gatatgacag cagatcatag ctttttttat
    31921 ccaaaataat cacgttcata cctcccttct ataaaacatc actaccacac agccttatca
    31981 gtttaccatt ttacctatct gtaggaaaga atactaggcc aaagtcaatt tctaaatagg
    32041 aaaaaacgaa cgatcattag ttttctgaag ataaaattcc taattagttc gcttttttct
    32101 tttataattg taatagttga attaattatt aaactttgtc taaaataaga ggctttttat
    32161 cccagattgc aacaagggtt aacaccttga ccttaagcct agctaagcag ctctcactaa
    32221 gttactagct gctgccttaa tgccggctac ctttttggcc ataataggca tttggaccat
    32281 gctttctaag gtaatgcttg tccataatat aggttggagc tggctccaca cgaggattga
    32341 tttgttctgt caggcggttc atcttggcca cctcttcgag caccactgag tgataaaccg
    32401 ctaattcagg cgtcttgccc caagtaaagg gaccatgatt gcgaacaaca ataccaggca
    32461 ctgccatcgg atcaagacca cgactagcaa attcctctaa aataaccgta cccgtttctt
    32521 tttcataggc tccattaacc tcatcggcag ttagagagcg agcacatgga atggggccat
    32581 aaaagtaatc agcatgagtt gtcccataaa atggaatatc tcgcccagcc tgtgcccagc
    32641 caaccgcttc tgttgagtgt gtgtgcacaa tcccgccaac ctctggccat gccttgtata
    32701 attgcacatg ggttggcaaa tcagaagaag ggttcagctc tccctcaaca atagtgccat
    32761 ctaagtctgt aacgaccata ttttccggtg ttaattggtc atagtcaacg ccgcttggct
    32821 tgatgacgat acgtcccagc tcacgacaga cctctgagac attgccccag gtaaatttca
    32881 ccagcccatg cagcggtagg gccttgttgg ctgcacagac acgttcacgc atttcttgta
    32941 gcctttttgc cattagctta accccgcttt ctcaatcagt ggataaagga aatcctgtgc
    33001 ctccttgatg gcagctcttg tctcctctac agtttcacag ttttctgacc acatttcaat
    33061 caaaaatgga ccatgataat gcgttttctt gagcacatca aacattgctt cccaatcaac
    33121 acagccttga ccgaatggca catcacgaaa ttgcccttta gatgtttctg tcacagcata
    33181 ggtgtccttt agatgcaagg cagcaataga ccgatgccca ttgtaaaatt cactccagag
    33241 gtcattatgc caagcagaga cattgcccgt atctggatag acaaagagat aaggggagtc
    33301 aatttctttt tccacagcta ggtatttctc aattgagttg ataaaaggat cgtccattat
    33361 ttcaatggct aaaataacct gagcttcctc tgcccaagtg caggcctgtc tgagattttt
    33421 gataaagcgc gcacgcgttt caggtgattt ttcttcataa taaacgtcat agccagccaa
    33481 ttgaatggta cgcacaccaa gatcctgtgc tagcacaatg cattttttca ttagctctaa
    33541 tgatgtcgct tctgtttctg gattgctaga gccaagtgga taacgacgat gaccagagaa
    33601 gcaaatgctt gggatacgaa cccctgtttc ataaatagcc ttgacaatgt ctagtcgctc
    33661 ctgtttactc caatccaagc gcgctaggcg agcatctgat tcatcgacag acatttctac
    33721 aaaatcaaag cctaatacct ttgcaaattg caagcgttcc agccaagtaa aatgctttgg
    33781 cgttgctttt tcatatatac caataggacg cgccatattg ttacccccaa atgcgtcgaa
    33841 tctcgtcttt aaaggcacgt gccgctgctg caggatcctc tgcttcagtg ataccacgac
    33901 ctgcaataaa ggtaaagaca ttaacccctt caaagagctt gagggtattg atatctaagc
    33961 cacccgtcac cgatacacga aagcccatgt caatgagggc tttgaccttg ttcagatctt
    34021 tttcacccca tacttcacca gcgagtaggg cgtcacgtga ttgatggtaa atcgcctgtg
    34081 aaatgcctgc atctagccac aattgtgcct gttcataggt ccaatcacca tacagctcaa
    34141 cctgaatctc gccacgttcc ccacgctctt ctttgatggc tttcagtgcg gctgccatgg
    34201 ttggaatagt ggcacagcaa atacaagtca tccagtccgc accacgctta gcattattct
    34261 tagcaacagt accgccagcg tctgcacact tggtgtctgc tacgatgatc ttctctggaa
    34321 ataagctacg cagcacctca accaattcgc tgcctacttg aagcaggcaa actgtccctg
    34381 cttcgattac atcaacctcg tgaccaactg caacagcagc cctgaccgcc ccctgcaaat
    34441 cagaatgatc taaggcaacc tgtaattttg gaatatgtgt catgattttc taccaagagc
    34501 ccgtagcacc gccttcaatg cttaatagcg agctcctatc ctttctgttg tgtttgattc
    34561 gtttagtgat gatggcttgt ctaagaatcc aaatccaagc cctctaaata aggactattt
    34621 ttggactcgt ccaccaaagc caaaacctct gctggagtgt gacaggcaac taagcgcgaa
    34681 atagcgtctt ccagttcaaa aagggcgaca atctgtggaa tagcaactgt tgtatgaata
    34741 gaaggatcag ttgccgccaa ggttagcaat accgaagcct ctttgccatc tgaaaaggtc
    34801 accggcttgg tcagtgtgat aagagcaaag gcatttcgct tgacccctac accagcctct
    34861 gcgtgtggca tggccattcc cggcataagg acataatagg gcccgtactt ttctgttgat
    34921 gcgataatag cgtcataata ttcagaggtc accgccccgc tgtcaatcaa aggctgaaca
    34981 gctagcttaa ccgcttcctg ccagctagct gctgacaagc ccaagcgaat agagttgttt
    35041 tcgataaatg ctttttttaa attcatataa ctatcctttc taaatcaaat tctttggcca
    35101 gacacttttt gcctcactcc tatctagctg ataaagagaa agagctggaa tctctcttca
    35161 caactctcac tccatctatc cttactgaaa gttgattgct acagcttagc ttacagccaa
    35221 gtggctgctc ttaggctcac tatcatttgc catgagcagc actgatgtca tcagggccgc
    35281 tctaaagcac cgcctgtagc ttggttttga tttcattgtc gtccataaga ttatctagtc
    35341 caaccaaatg accctttgta cgcccatcta attcatgaat caggtgatta gaagcaacca
    35401 caatatcata gcctgaggca agtccctttg cctcacccac tgagcaagaa gcagactgaa
    35461 tatcagtcac cccaagctga cgaagtgcgt tttcaacctt cattttaata accattgatg
    35521 accccatgcc attaccgcat gctgtaagaa ccttaaccat ttattttcct ccgaatatat
    35581 gataatttga tatgaatgaa gacctgcaga agtatatcga caaactccta ccagcctgtg
    35641 ctaaaagacg aataagcagc tattatcacc ttgcttattg tgcttcaccg cggtagtaag
    35701 cctctttatc cttagcccta gcaaattgta gctgtggaat agcaagtaag aagacacaca
    35761 ccaccacata gcctgcaata ccaaggaact tgaagagata accaaatgga agccaaggaa
    35821 gcaccaggtc aatattgcca tgataaccac ctgtcaagcc caacagacca actgccactg
    35881 cacctaaggc aacctgaaga atacctgata taaaggatag agcaacagct gccttccagc
    35941 caccacgctt atctgcataa acagcaatcg cagcattatc aaagaagacc ggaacaaatc
    36001 ctgtgatgat caagattgga tttttaaaga tcacaagaag tgcaatagtg attagctgac
    36061 cgataagccc aaaggtaaat cctgacaaaa cagcgtttga agagccaaag ccatatgacg
    36121 ctgcaacgtc caccgcagga aatgaacccg gaaggagctt acttgaaatc ccttggaagg
    36181 cattggtcaa ctctgacaca aacatacgca caccctgcat caggataaag agataaactg
    36241 agaaagttaa ggaggtttgc aaaatataca taaagaaggc ctgcttagct ggattaaagg
    36301 caccagcacc tataagttct gcattagaca tcatatctgg gccaagcaca gccaagatag
    36361 caccaaagaa aaccagcatt agagtggcag aagcaaccac cgtatcatga aaaatcgtta
    36421 aaaagcttgc tagcttaaga ttgtcaaggt tctcttcttt tttaccaaag aaaggcgcca
    36481 ccttgtcaac aaaccagatc gcaaactgct gctggtgccc aatggcaaag cctccaccac
    36541 ctgtcaagcg ctgagtcgcc tcaactgtca tattggagct gacagcccag taaaggccac
    36601 agataatacc gaccgcccaa gcaccaaaag cattttgaag ctgagggatt aaaagaagaa
    36661 caaacacaga gatggttgcc gcctgctgca ccatgatatg acccgtaata aagagcgtac
    36721 gaacctttgt caccttacga agcgccacta gcaaaatatt gaccccaaaa ccgatcaaaa
    36781 gggctgtggt ggcaacgctg atggatccca tctcctctag cttggtattg gctgctgcaa
    36841 gtccaaagta agggtcaata actgcggcct ttaattcaaa tttcttaccc aatgccacta
    36901 ggattgggcg aaaggtgtta accaagcccc cagcaccaac attcaaaatc agataaccaa
    36961 ccgttgcctt aacaaagcca gcaaatactt catgcagggg ctttttaagc agcaaatacc
    37021 caatcaaaac caaaagacct acaaagaaag ccggattttg caaaatatct tgcgaaaacc
    37081 agtttagggg agctataagc attttcataa gaactacctc ttttcacagt taataaatat
    37141 gatattttct atacaataat tgtaaacgat gtaagcgttt aaaaaaaaga ccaacaatca
    37201 cacaaagaag tgttcaaaaa tgtactgaag ccaatttcca gctagctctg atcactgtta
    37261 aagcactatc attaatctct aattaataac caaacacatc acaacaatat cgggctaaca
    37321 caaaaatagg ccagcccata ctgcccagcc aaaacgaaac aagcaatcaa ttcaaggcac
    37381 ttaaccctgt tttatatcgt acaaagccct tttaagatga ttttgtttgt ttcctaatcg
    37441 taaattagtt atctgatccg ttctctcctc agatatactc acccttatct aattctactg
    37501 tcaaatagct acttactcat aagcaaatga atattaagca accaccaagc tacaataaaa
    37561 gaccttaccc tgttggcaag atcttattca ttatacaatt tttccttctg cgacatggac
    37621 tacctcatca cacaagtctt caatatctgt cttcagatgt gagcttaaaa tcacaagccc
    37681 atttttgcta acatctaaaa gcaatttttt cgtttgctcc acgctcctgt catctaatgc
    37741 attcattggc tcatctaata taaggatctt agggtgatgc atcaaggcct gaattaaccc
    37801 taattttttc ttagtgccta gcgattaatg cttaaatgct gtttgactaa actgatgtaa
    37861 atgataaaca tctaaccaaa aagctaaatc aatatctcta gccttaggag agattgacct
    37921 aagcaactct agattttgta acaatgttaa atgtgcaata aactctggat tctcaatcaa
    37981 aatcccagca tcctcgatat aattatggta ctgtctaatt tttttattgt cctgataaac
    38041 agctccttca tctaatttga tataaccagc taaggcctta agtatcaagg tttttcccga
    38101 accattaata cctaccaaac catagatatt accttcttta aaagtaagat taatatcatc
    38161 tagaacaagg ttacccttat acagttttct accatgttca atccgtaaca tctcagctct
    38221 ccttataata attgtcataa agcatatgta ccaatactat tagcagcagg caccaccaaa
    38281 catcaaacaa aaagtaacgt atcaaggtga gactagcaaa caagatcata gctactacag
    38341 cagatgaggc atagcgtatc ataacataaa tcaagcaaat atctatagta agccaagata
    38401 ccataagata acatagtcgt tcaatatgat atggtgcacc ataataggtc atcaatacac
    38461 ctaatattaa aacgataaaa agtaaccact ctttaatata gaaaatcgta ctcgtccgcc
    38521 atagcttgtt aaaaaatacc aactgacttc gagcatgaaa acgaaagatt tccttagttc
    38581 cttcagccaa atccgccaaa aatgaaatcg taaaataaaa gctgttgaag gacaagccta
    38641 gcaaggtgat aaccttgaca aaatcagctg tctccccttc aatcactgga aacggcatta
    38701 gcaaccgata gcacactaaa ttatgaaaat ctcgctcccc agtcatatta gccttaatca
    38761 ataaaagatg tattagtaag ccagtaagac atgctttcat tccaacaacc agcaggttag
    38821 ataatttcat ggtgcttcct caattttaaa acgatgcaca cacccactaa gcctaaataa
    38881 ggtgataaaa ggtaaggaat atcagcatca ctataagatg ttgacatcaa agaagtcata
    38941 agaacatatt tgggaggtaa atagctatat aacaacggtg acaaagccca catcaaaatc
    39001 aaatagagca tgcttgactt aataaaggat tgaagatagt caacaagaaa acaaacgaaa
    39061 tacgtatgaa cgaacaaagc taacgatttt actaagcaat agtaagctat aaaggttgtt
    39121 gctccttgac caaaaaaacg caatattgag ttttgatcaa aataaggcat taaattaccg
    39181 ttcatatggg caacaccatt tagccaagac actaaagtca aagcaaatat tacaatgtaa
    39241 aaactcagta aaacatataa gctcaactga agctttaaaa aaatacacct tttaccatag
    39301 tcagactttc tgccaatgag gtatttaaga tgtcttgact taaggtaata gtaggcatag
    39361 gccactaaaa tcatcactag tggatagata aaagattgat aaaaactaaa atcaaacacc
    39421 acactatcca aacgtatcat actcaacaat agacttttct ttacctcaat tccaccagat
    39481 aaatctactg cacttgtatc aaaaaataag atatgcttca aactgtcaaa ataaataaaa
    39541 cctaaaaata gtaacgggac taatggataa aaatagcgaa atggaaataa tctatactgt
    39601 agcatttatg aataactccc ctacaaaaaa tcaaggaaac gcctcgttac taactcaatt
    39661 cacaattgta gatatttacc aattgtctgg agaccaacta ccactaatgg ttgttgctcc
    39721 gtcccaccaa ttttcacgta ccagatgcaa ggcataaagg tacccacttt tagtatcctg
    39781 tgtataaatt cctctgtcgc ctgtccaagt tttatctata tcacttcttc tttgaccgtt
    39841 actattagct agatagtgcc ttaccacaat ttctctatta cgtcctcttg aatctaaatt
    39901 aacgacataa taaggcgccg cactcttcac aagataatct ttcgtccttc caaaagatga
    39961 cgtgattcta aaattttgca agtaaccaat ttgtcgttct gctataacta aagaactaat
    40021 caataatgta gaagctacaa ttgccaataa tccaatctta attttgccta attttatttt
    40081 ttaataattt ataattttta tatatttagc acatcatcag cgcttccttg acaattgata
    40141 atacaattca tgctaggctt aatcgataaa actaaatact agatagtaat caacaccagt
    40201 aaaccaagat tgtaaaccct ttctttttcg tttatatttt aacattaata ttatttttgg
    40261 tcaataacta tttttgtttt atcataaaaa ctatataatt tatcattaaa ttaacagaaa
    40321 aatggtccaa aaatactatt ctgaaccatt tttcttataa attat
//
LOCUS       DARYYD010000015        39096 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.015, whole genome shotgun sequence.
ACCESSION   DARYYD010000015 DARYYD010000000
VERSION     DARYYD010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39096
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.015"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(93..464)
                     /locus_tag="TV188_000704"
     CDS             complement(93..464)
                     /locus_tag="TV188_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534080.1"
                     /translation="MKLRRKTRLTKIGAPMTVNIGKSHKVKLYPGESIDIDLPDAEDY
                     LTIKHSRQAKKIVTNQDQVTITDNPINLILFWSGVVLVLGSHLVLSFDSSWLYWLTII
                     GLSSIIVSYLVPRFKWVVTQS"
     gene            683..1321
                     /locus_tag="TV188_000705"
     CDS             683..1321
                     /locus_tag="TV188_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HEL1534081.1"
                     /translation="MVKGIIFDMDGVLFDTEPFYLKRREAFLTSKGIRIDHLSPEDFI
                     GGNLQQIWDKVLAGQANADEARDIAVAYEAYKLCHKPPYQELMFKGVKSCLKALKGQG
                     LKLALASNSSRCDILLALESSHIKAYFDLTLAREDVTAGKPNPEIYNKVAQALGLAKA
                     EFVVVEDSQKGIAAAKAAGLKVLAIKDKRYGIDQGQADKRIDSLRQLCELLR"
     gene            1517..2053
                     /locus_tag="TV188_000706"
     CDS             1517..2053
                     /locus_tag="TV188_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1534082.1"
                     /translation="MLSLLIGGLMAVKLLTERLIIQELNETYFEPYHKAFTEEITAFQ
                     WPDPFKDIAAAKETLASFIAEMKKGNMLELVILNKANDFVGSLEVFSLDSETPELGIW
                     LKKSSQGLGYGYEALRAIVDYLKGKNKYRYFNYEVDVRNTGNIKLVEKFNVVTSTYQE
                     CETASKKRLCLQVYHILN"
     gene            2916..3320
                     /locus_tag="TV188_000707"
     CDS             2916..3320
                     /locus_tag="TV188_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEL1534083.1"
                     /translation="MTEIPKDLKLNTISVFEHYHIDVFEAGHVLLSTEIHASALNYYG
                     NAHGGFLFTLCDQVGGLVAKSIGLEAVTLQANVNYLKPGHLGDRLVVEGSLVHRGRTT
                     QLIEVTIKNQDDRLLTRVSLTMFVTSKKRSSD"
     gene            complement(3376..4860)
                     /locus_tag="TV188_000708"
     CDS             complement(3376..4860)
                     /locus_tag="TV188_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEL1534084.1"
                     /translation="MKNIAFDSNKYLSLQRNHILERIKQFDGKLYMEFGGKILEDFHA
                     ARVLPGYEPDNKIKLLKELKDQVEIVITINANNIEHSKTRGDLGISYDQEVLRLIDTF
                     NALDIYVGSVVITQYNHQAAADHFQKQLAKNGITSYRHYPIKGYPTDINHIISPDGMG
                     RNDYIKTSRNLIVVTAPGPGSGKLATCISQLYHDQLKGVTSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLEAYGKTAVNYNRDIEVFPVLNRTFERILSQSPYA
                     SPTDMGVNMVGFSIVNEEAAIEASRQEIIRRYYQTLVDFKAERVTEAAVKKLELLMND
                     IGVTPKDRQVTLIARQKAEITGQPALALQLPNGQVVTGKTSDLFGPTAAVIINAIKTL
                     AHISKETHLIEPEYVKPIQGLKINHLGSHNPRLHANEILMALAITAMNNNQADLAMKE
                     LGNLKGSEAHSTVILTNEDKHVLRQLGINVTFDPVYQHHKLYRS"
     gene            5219..6442
                     /locus_tag="TV188_000709"
     CDS             5219..6442
                     /locus_tag="TV188_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1534085.1"
                     /translation="MSALSLDKNNKRALWAAIAASGTDDLNVMFLAFSMSSIISDLGV
                     SSTQGGWIATITNLGMLFGGLLFGLLADRHHKFKVFKWTILIFSVATGLIYFTKTIEF
                     LYLMRFIAGIGVGGEYGVAIAIMAGLVPAEKMGRVSSLNGIAGQVGSIVSALLAGWLA
                     PALGWRGLFLFGLAPILLVIWMMVAIDDDKIIDNHVNVSEEASQPVKISELFKTPALT
                     GQTLALMVMTTVQIAGYFGMMNWLPTIIQASLHISVKDSSLWMVSTIVGMCLGMLTFG
                     HLLDTFGPRLVYSIFLLLSSVCVYLFQFANSMSTMLIGGAIVGFFVNGMFAGYGAMIT
                     RLYPHHIRSTANNLILNVGRAVGGFSSVIIGKILDVSSVSMVMLFLALLYLVSFVALW
                     TIKNLKAERYQALTK"
     gene            complement(6532..6891)
                     /locus_tag="TV188_000710"
     CDS             complement(6532..6891)
                     /locus_tag="TV188_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HEL1534086.1"
                     /translation="MSIYSQLYETKSKHSAQAMGSGGLEVLATPALVAFMEHAAFTFL
                     QSQLKDKQTTVGSEIAIQHLAASKIGQAVTIVITALKEEGRKYDFRIEAFANHKLIGR
                     ACHTRVRVDQDAFLEKL"
     gene            7056..7769
                     /locus_tag="TV188_000711"
     CDS             7056..7769
                     /locus_tag="TV188_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1534087.1"
                     /translation="MRLDKFLVDAGLGSRSQVKLLLKKKQVSVNGVSQTSPKYQVNEM
                     TDEVSYQGQRLNYEAFVYYMLNKPKGVISATEDSSHKTVLDLLDDTARQKAVFPVGRL
                     DKDTHGLLLVTNDGKLAHALLSPKKHVAKQYLAVVDGMMTQEDVKHFAQGITLKDHQC
                     MPAHLDILEINESLKTSLVKITIEEGKFHQVKRMVAACGKTVSDLQRISMGPLQLDSA
                     LAPGAYRRLTAAELEALKA"
     gene            complement(7848..8675)
                     /locus_tag="TV188_000712"
     CDS             complement(7848..8675)
                     /locus_tag="TV188_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018164168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEL1534088.1"
                     /translation="MVLPHFDDYLEKYANLLIKKGVNIQKGHTLLISIAVEQHKLARL
                     LTKKAYEAGAAEVLVDYNDDQITREKLLKADEDRLLQVPDYVVEQSHYLLDQKASRLV
                     IRSANPNVFADIDSDRLAGATRATAIALEKQRAATQANKVSWNLAAAAGPEWAAMVFP
                     NLTSEEEQVDALWDAIFKMNRIYETDPVKAWDQHQERLEKKARLLNDYQFDSLHYRAP
                     GTDLRLGMPEQHIWEAAGLNRSTAHADFMIGSEQMDIDGITKDGEVIPIFRGGEWAI"
     gene            8936..9064
                     /locus_tag="TV188_000713"
     CDS             8936..9064
                     /locus_tag="TV188_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEL1534089.1"
                     /translation="MAFGENGPRKKTAFEKLTTVVVIVMVLVTVGGLIAGALSVLM"
     gene            9118..10431
                     /gene="obgE"
                     /locus_tag="TV188_000714"
     CDS             9118..10431
                     /gene="obgE"
                     /locus_tag="TV188_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEL1534090.1"
                     /translation="MSMFLDTAKVSVQAGRGGDGMVAFRREKYVPNGGPWGGDGGKGG
                     SVIFKVDEGLRTLIDFRYNRKFKAKSGEKGMTKGMHGRGSEDLIISVPQGTTVRDAET
                     GKVLTDLVEHGQEFVVAKGGRGGRGNIRFATPRNPAPEIAENGEPGEERQLELELKIL
                     ADVGLVGFPSVGKSTLLSVVSSAKPKIGAYHFTTIVPNLGMVRTKSGESFAMADLPGL
                     IKGASQGVGLGTQFLRHIERTRVILHVIDMSAAEGRDPYEDYVAINKELEAYNLRLME
                     RPQIIVANKMDMPEAKEQLQRFKEQLAAQYDDFEELPIIFPISSLAHQGLDSLLEATA
                     ELLAKTDDFLLYDEADLAEDEAYYGFAAEEKAFEISRADDAAWVLSGEKLERLFVMTN
                     LERDESIMKFARQLRGMGVDEALRERGAKDGDIVRIGKFEFEFVD"
     gene            10552..10710
                     /locus_tag="TV188_000715"
     CDS             10552..10710
                     /locus_tag="TV188_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534091.1"
                     /translation="MGDKPISFKDKDGNFVSAADVWNAEKLEELFNLLNPNRRLRLER
                     DKLKKDEA"
     gene            complement(10763..11467)
                     /locus_tag="TV188_000716"
     CDS             complement(10763..11467)
                     /locus_tag="TV188_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HEL1534092.1"
                     /translation="MAYLNYFTKTEWTLWLTSISAILLSAFFFGEQAPLALIASLIGV
                     TALIFSAKANPIGQSLAIIFSLIYAYLSLLNSYYGELITYLFMTLPMAILSLFTWLSH
                     PFEDQTSQVTISRLTTADRLRLVVLTILVTSLFYAILAYLKTAYLPVSTLSIATSFSA
                     AYLSYKRSPYFALAYALNDLVLILLWLYAAQANTSQYAVVICFAAFLVNDIYTFFNWL
                     HLQHHQEKKHQKRTKP"
     gene            11802..13202
                     /locus_tag="TV188_000717"
     CDS             11802..13202
                     /locus_tag="TV188_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1534093.1"
                     /translation="MKQSKRRYQFPEGFLWGSSTSGPQSEGTVSGDGKGPSNWDYWFS
                     LEPDKFHHQIGPEVTSTFYTNYKSDIALLKETGHTAFRTSIQWSRLIPEGVGQVNPKA
                     VAFYREVFQEIMAQDIKLIVNLYHFDLPYALQGKRGWEAKETVWAYETYAKTCFELFG
                     DLVDTWITFNEPIVPVECGYLGHYHYPCKVDAKAAVQVAYHTQLASSLAIKACHELYP
                     KHRISIVLNVTPAYPRSDQPEDVKAARIAELFQTKSFLDPSVLGVYPEELVVLLEAAD
                     LLPQYSADELAIIKNNPVDFLGVNYYQPLRVQAPSKTRQDGEPITLASYFEPYDMPGK
                     KVNPHRGWEIYEQGLYDIALNLKEHYGNIDWLVTENGMGVEGEEAFLVDGQIQDDYRI
                     AFIEDHLIQLHRALEEGANCKGYLLWTFIDCWSWLNAYKNRYGLVALDLETQKRTLKK
                     SGHWFKTLSQTNGFDK"
     gene            13212..14306
                     /locus_tag="TV188_000718"
     CDS             13212..14306
                     /locus_tag="TV188_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HEL1534094.1"
                     /translation="MVTLGFSLYPERHGFAKSKAYIDLLHCYGAKRLFMSLLQLAPND
                     PKTFKFYADLIAYANCLGIRVIADVSPAFIKQAGWSDQVIEEAHAFGLAGLRLDEALP
                     LEDIVRLTKNSFGLKIELNMSTDKSLLTALLKAAPDRSNLIGCHNFYPHAFTGLSLEH
                     FKEMSHFYHEHGIATAAFITAQSAKEGPWPLSEGLPTVEAHRQLPIDVQVELMKATGT
                     IDTVILSNQFITEDELVQCRQALDRSVMSIKVKPLVDLTDIEEKIICYPHCYRGDVSD
                     YVIRSTMPREVYAQEAIAPREQPKQVKRGSIIIDNDRYNRYKGELQIALKAFTLSSKA
                     NVVANIKEDYLSLLDELKPWQEFSLVIETD"
     gene            14412..16406
                     /locus_tag="TV188_000719"
     CDS             14412..16406
                     /locus_tag="TV188_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEL1534095.1"
                     /translation="MLSKKEMAIVAFLISQKGQFVSSATLAKAIGMSDRTVRKYLKEL
                     ISSLPSKGAHIISKQGQGYCLEIDHSMAFEIFWQESLASKKRLADVTQVEETVDREHY
                     LLNKFFFEEPVWDFEELCQELYISRTTLNHVLAVIRDRIRPYQLQLDVSHQRVQVTGK
                     EEAIRHFIMDYFFATSFDDSMYAIVDNTFLDHIKFADITIIVLDECRDAKLKLSDFVM
                     HNLVLHIALMVQRIRSGYPLAFFSIPAAIRQSDEYQVALRILYRVEEVMGIRFPKEEA
                     NYIALHLKVKHSVDGSPQDNKADDLLRSHLKAGIVKASQLTGMSLEADSSLLQGLLAH
                     MKPLATRLENHIQLTNPLTEEIKSKYPEAFALTKQAFENIPELQAYDLSDDEWAYISL
                     HIMAAIERYSNRHKLRVLVVCATGYGSAMMLKNRLEKEFEGRFQIVDVISYYEITQER
                     LQTVDVIISSISLANVMFLTPVITVSVFLSDQDIKAIRQFIGEQEGIRREAASSSQMS
                     LEKAEQILKGVFSPKRFLYVKEKLSKKALLLKMIACLDEAMDEAFVEAFYHQIVLREN
                     YSSIVFGEVLAFPHPANPMTYSEQVVVAVCQEPIDWDESHRAVHFIFLLSPSKGRNSY
                     LKYISPSLVSFVNQAELQQALLEEPSYAQFITLFTPLITE"
     gene            16420..16737
                     /locus_tag="TV188_000720"
     CDS             16420..16737
                     /locus_tag="TV188_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1534096.1"
                     /translation="MKTIMLVCNAGMSTSMLVTKMQKAAQARGIEVEIWAVPVSEADN
                     EVAAKTIDVLMLGPQVKFLLKDFKTKFEPAIKVDVINMADYGLMNGDKVLETALTMME
                     EEV"
     gene            16734..17069
                     /locus_tag="TV188_000721"
     CDS             16734..17069
                     /locus_tag="TV188_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1534097.1"
                     /translation="MTQSSNLEAIMGLIMYGGEAKGKAVEAIHAARDGQFEKAQHLLQ
                     EATHSLNVAHRSQTNLLSQEAAGDQVDLSLLLVHGQDHMMTALAFIDLAKELVAVYDK
                     ISRIQRGEL"
     gene            17069..17503
                     /locus_tag="TV188_000722"
     CDS             17069..17503
                     /locus_tag="TV188_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HEL1534098.1"
                     /translation="MMITAEGDVSVTQCFKAILSSLQEDYHENTLRRLPPAELKAGLS
                     YIKHYGKSKEHNVRVLITALEAPHLYAACFSSNHGLKTLSYRLEALGEKRTKITYCYD
                     YQPLDVFQKANQLIIGKLFKKSFKRQSQAQLAALIQYAKQLS"
     gene            17578..18957
                     /locus_tag="TV188_000723"
     CDS             17578..18957
                     /locus_tag="TV188_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1534099.1"
                     /translation="MSHFSDKFMEISGKMGSQRHLVAIRDSFISLMPITMAGSVAVLL
                     NVFLRDIPNNMGWTGFAAAMQPIIDINGYVYFGTIGIMALFFAFAFGYHLALMHKVNP
                     LAGGLISFASFVATLPQSLTISTPLEGASASLLAGLKDMGLSVVTANGARVLETSQWG
                     AIALKYAGATGLFTALIIGFLSSFVYATLTKRNLTIKLPDNVPPAVNKAFAAIIPGTV
                     AIYVSAIVAYLIFALTGSSLSDMISTYIQLPLLGLSQGLGSVILLTFLVQLLWFFGLH
                     GHNVLAPVLDGVYLVALTENTAAYNTSQSVANLPYLWTRGSFDAYAQMGGSGVTLALI
                     IAIFIFSKREEHKTIAKLSAPMGVFNINEPITFGMPIVLNPTFAIPWLIVPPICASIA
                     YAATAIGLIPPVFLPVPWITPVGLYAYLATGGSVMAGLVSLFNLFVAFLIWAPFVMSA
                     NKEKASDLS"
     gene            18954..19106
                     /locus_tag="TV188_000724"
     CDS             18954..19106
                     /locus_tag="TV188_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534100.1"
                     /translation="MTAKNGASFLMAIGFFLIAISPMVGNKYLHIVTGLAFVGLGYYL
                     TKRKRP"
     gene            complement(19263..20003)
                     /locus_tag="TV188_000725"
     CDS             complement(19263..20003)
                     /locus_tag="TV188_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003107174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1534101.1"
                     /translation="MAELKIDVQDLHKSYGQNEVLKGINAKFYEGDVVCIIGPSGSGK
                     STFLRTLNLLESITSGKVVVDGFELSDPNTNIDKARENIGMVFQHFNLFPHMTVLDNI
                     TFAPVELGKVSKEAAKEKGLALLEKVGLADKADAFPGSLSGGQKQRVAIARSLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKDLAEQGMTMLIVTHEMGFARQVANRVIFTDGGQF
                     LEDGTPEEIFDHPKHPRLIEFLDKVLNV"
     gene            complement(20003..22168)
                     /locus_tag="TV188_000726"
     CDS             complement(20003..22168)
                     /locus_tag="TV188_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1534102.1"
                     /translation="MKNTLKAWMLAMLSVVLMTAGIASAETIDIVSDTAYAPFEFKDS
                     DQVYKGIDVDIINEVAKRKGWNINMTFPGFDAAVNAIQSGQADALMAGTTITAARQKV
                     FHFSDPYYDTKIVIATRKANPIKKYSELKGKTVGVKNGTAAQAFLDKYKKSYGYTVKT
                     FDTGDLMYNSLATGSIDAVMDDEPVIQYAINQKQDLAINMKGEAIGSFGFAVKKGSGY
                     DYLIDDFNEALGAMKADGTYQAIMTKWLGSNDKVTAGKATGDASAKATPLKPVYKIVA
                     DSSFAPFEFQIGSGEYVGIDMDLIKAIAKQQGFTIEISNPGFDAALNAVQAGQADAVI
                     AGMSITPARREIFDFSDSYYTSNIRLGVKSGSSIKSYKDLKGKIVGAKKGTASYDFLE
                     SNKDIYGYRLKAFDEASSMYDSLNSGSIDGLMDDEAILRYAIQRGHKLDIPIKGEPSG
                     EYGFAVKKGANPELIEMFNNGLAALKASGKYDAIISRYLDSEASVKTADESTIYGLLA
                     NNYKQLLAGLGTTLGLTLISFAIALVIGIVFGMMAVSPSKNLRMASTIFVDVVRGIPL
                     MIVAAFIFWGVPNLIESMTGHQSPINDFVAATIALSLNGGAYIAEIVRGGIEAVPAGQ
                     MEASRSLGLSYHTTMRRIILPQAIKLMLPNFINQFVISLKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFRMYAILAVIYLIMITLLTRLAKRLEKRLN"
     gene            22360..24351
                     /gene="uvrB"
                     /locus_tag="TV188_000727"
     CDS             22360..24351
                     /gene="uvrB"
                     /locus_tag="TV188_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002261961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEL1534103.1"
                     /translation="MIDKRDFKAFKLVSKYAPSGDQPQAIETLVDNIEGGEKAQILLG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVVASVSCIYGLGSPKEYA
                     DSAVSLRPGQEISRDQLLNALVDIQFERNDIDFQRGRFRVRGDVVEVFPASRDEHAFR
                     IEFFGDEIDRIREIESLTGKVLGDADHLVLFPATHFVTNDEHMEQSISKIQAELADQL
                     KLFEAEGKLLEAQRLRQRTEYDIEMLREMGYTNGVENYSRHMDGRSAGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDKARKQMLVDYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYEMEQTDTIVEQIIRPTGLLDPEVEVRPSMGQMDDLLGEINLRVERG
                     ERTFITTLTKKMAEDLTDYLKEMGVKVKYMHSDIKTLERTEIIRDLRLGVFDVLIGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNADGHVIMYADRMTDSMQ
                     RAIDETARRRAIQMAYNEEHGIIPQTIKKDIRDLISISRAVEAKATEAETNYESMTRS
                     ERQEAIKQLQKNMQEAAELLDFELAAQLRDLILELKAMD"
     gene            24690..24833
                     /locus_tag="TV188_000728"
     CDS             24690..24833
                     /locus_tag="TV188_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEL1534104.1"
                     /translation="MLKNKSRLRAIFVFVGKIALFYVILMLLVYFFGYLGHGQSNFIY
                     NEF"
     gene            24845..26383
                     /gene="dltA"
                     /locus_tag="TV188_000729"
     CDS             24845..26383
                     /gene="dltA"
                     /locus_tag="TV188_000729"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEL1534105.1"
                     /translation="MVNDMIETIEYFAQAQPDFPVYDCLGERRSYGQLKEDSDSIAAL
                     IESLKLGEKSPVLVFGAQSYDMLASFVALTKTGHAYIPVDVHSAPERVLSIIEIAQPS
                     LIIAIEELPVSIDAIRVVSLAEIEAAKAAKAAFTMTSPVKGDDNYYIIFTSGTTGQPK
                     GVQISHANLLSFTNWMIEDAEFAIPERPQMLAQPPYSFDLSVMYWAPTLALGGTLFAL
                     PKEMVSDFKRLFSTIAELPIGIWTSTPSFADMAMLNDDFCQEKMPRLTHFYFDGEELT
                     VSTARKLFERFPDARIINAYGPTEATVALSAISITKDMIETYTRLPIGYPKPDSPTYI
                     IDEAGNALEPGQQGEIIVTGPAVSKGYLNNPEKTAEAFFTFNGMPAYHTGDLGSFTED
                     NVLLYGGRLDFQIKYAGYRIELEDVSQQLNQSPLVESAVAVPRYNKEHKVQNLLAYVV
                     LKDGVREQFARDLDITKAIKASVKDHMMAYMMPSKFIYREKLPLTPNGKIDIKFLINE
                     VNHQ"
     gene            26380..27627
                     /gene="dltB"
                     /locus_tag="TV188_000730"
     CDS             26380..27627
                     /gene="dltB"
                     /locus_tag="TV188_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEL1534106.1"
                     /translation="MTTLFHHIPYMEPYGNPIYFVYLIIAFLPVIIGIFKQRRFSTYE
                     SFVSLIFILLMFGGEHYQQLLAFLAYLIWQTISVLAYKHYRQKANAAWVFYLSILASL
                     FPLICVKVSLSLTRSFFSFLGISYLTFKSVGMIIEMRDGVLTDFSLKDFLRFMIFFPT
                     FSSGPIDRFRRFQEAYTKLPSRDVYLDMLNKAVMYLMLGFLYKHIISYCLGGLLLPLA
                     ENKALTVGGYFNKETIYVMYLYGLNLFFDFAGYSMFAIGLSYLLGIKTPENFNKPFLS
                     PNLKEFWNRWHMSLSFWFRDFVFMRLVHLLIKHKTFKNRNVTSGFAYLINMLVMGLWH
                     GLTWYYIAYGLFHGIGLIVNDAWLRKKKEINRRRKKQGLKPLFEGKVFHALSIVVTFH
                     VVLFSLLLFSGFLNELWFSRPLR"
     gene            27645..27884
                     /gene="dltC"
                     /locus_tag="TV188_000731"
     CDS             27645..27884
                     /gene="dltC"
                     /locus_tag="TV188_000731"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEL1534107.1"
                     /translation="MSTKETVIDLFDRLFMEDVSDMMDEDLFDAGVLDSLGTVELIVE
                     IESIFNIKVPISEFGREDWNTANKIIQGIEELQHA"
     gene            27877..29130
                     /gene="dltD"
                     /locus_tag="TV188_000732"
     CDS             27877..29130
                     /gene="dltD"
                     /locus_tag="TV188_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEL1534108.1"
                     /translation="MLKRLWLILGPLIIAFGLVCLTIFSFPTKLSYSLRQEKSNAVAI
                     NDSSFKNGLIKRQALSDPNYCFVPFFGSSEWSRMDSMHPSVLAERYKRSYRPFLIGKR
                     GSASLSQYYGMQQISQEITGKKAVFVVSPQWFTPQGIDPGAVQLYLSNSQVIDFLLKA
                     KASHKESQFAAKRMLDINPGVAKSELLRKISQGKALSRWDIRLLKWQQELSLREESLF
                     SFLGRSTNYEDRILPRVKGLPKTFSYERLSELAARRAKEGTSNNRFGIKNAFYSKRIA
                     PQFPLYKNFQCRNNYTVSPEYNDFQLVLSEFAKRKTEVLFVITPVNQAWANYTGLNQR
                     RYQKAVRKIKHQLTSQGFTRIADFSRNGGDKYFMEDTIHLGWNGWLAFDKEVVPFLED
                     QTPPSEYQLDPYFLSKDWADRTAGF"
     gene            29164..30138
                     /locus_tag="TV188_000733"
     CDS             29164..30138
                     /locus_tag="TV188_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1534109.1"
                     /translation="MLMSIIVILLILAIAVLVIEYGQKRSFSSWLLEKMFDYRKYKLS
                     KKADDYEGIETQRRRRIPYHLDNPEAVLGIPTTEYTIDGMQVFVINDQDSQDQPVIYY
                     LYGSVYLRRPETFHFKTIKHLIHLTNAKLVFPNFEKAPYVTYKEIYPKLAKTYQELCL
                     ANGAAKVSIIGDSSGGGMALALAQYLRDTQTAPQPKQLILLSPWLDVSFANQDYKHFE
                     AVEAYLDARRLRDIGELWAGSPEEMRSPYVSPLYGDYHDLPKIVTFVGTKEIFYPDIM
                     TLHERLMEQGHLNQLVIAEQMIHAYAIFPIREARQARKQIAELILKKE"
     gene            30679..31938
                     /locus_tag="TV188_000734"
     CDS             30679..31938
                     /locus_tag="TV188_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1534110.1"
                     /translation="MAWDWKKAGVVGVVSLASIMVLSACSGGHQKEAKQKDDNTIVVS
                     VDEGYADYIKEIKTAFEKDNKVKVKVKKEGMIDTLDKLSTDGPTGASPDVFLAPYDRV
                     GGLGSEGQIAEVSLGNADQFDDTVKKLVTINGKVYGAPDVIETLVMYYNKDLVSEAPK
                     TFTDIEELNKDPKFAFASEDGKSVGFLAKWTDFYYGYGLIAGYGAYVFGDKGTDPKDL
                     GIGNAGAIEGLDYAKKWYSVWPQGMQDTQKAGDFITEQFTSKKAGVIIDGPWAAASFK
                     EAGVNFGVAQIPSLPNGGSYQAFGGGKAWVISNYSKNKKLAQQFLDYVTNEKNQKAFY
                     DKTQEIPANLAARSYAAEQGNELTKAVIGQFSNAQPMPNIPEMAEVWGPGANMFFEVA
                     AGKKTPAKAAKEAAKTIQEAIAQKYTE"
     gene            32111..33811
                     /locus_tag="TV188_000735"
     CDS             32111..33811
                     /locus_tag="TV188_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEL1534111.1"
                     /translation="MNTAGILHIPDSRYCFALSTKELVIRLRVAKEDNDIAVTLVYGP
                     KYHYHEYQKELAMYAAYTDHTHTYYEITLSLDDVRLAYIFKLEQSGHTYYFSEDGLTT
                     SYDFSNGFYNFFQMPYINAVDVHQTVPWVHNAVFYQIFVDRFHRGDFEKDDSYINMAW
                     LDRPTPNSFAGGDLKGITDKLEYLEDLGINVIYLTPIFKSISNHKYDISDYYAIDPMF
                     GTSLDLQQLINEAHQRGIRIILDAVFNHASSDCEPFQDVLAHGSASSFFDWFMIQGDH
                     PSVELANYETFADCHYMPKWNTSHQAVQDYLIEIGLYWITEYHIDGWRLDVSDEVSHD
                     FWRRFRKAVKAVKSDAILIGENWHDAYPYLQGDQYDGIMNYAFTKACLDYFAFDAISS
                     QEMAERLSHILMRNTWQVNQMNLNLLDSHDTHRFLTQVNGSKDKLLAGLALLVTFMGI
                     PCIYYGTELAMEGGYDPDSRRSFNWDSSTWDMSFWNQVKDIISLRRHAVIQFGSISIT
                     SHDDCLCVKRELNGQSIRLLVNNGVKPYPIEKGGSVLVSNGVDKETFELLQNGFVVSY
                     "
     gene            33840..35972
                     /locus_tag="TV188_000736"
     CDS             33840..35972
                     /locus_tag="TV188_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IPT/TIG domain-containing protein"
                     /protein_id="HEL1534112.1"
                     /translation="MKRITLTCRKALTVAMAAVTLAMSTNSVFAIENTAVSNKADFST
                     DTIYQIVTDRFHDGNAANNGNTDVFDKNDPKKYHGGDWAGIIKKLEDGYLTNLGVSAI
                     WISSPVENIDTIDPSNGSAAYHGYWAKDFFKANSHFGTMEDFKKLIQVAHGKNIKVVI
                     DFAPNHTSIAEYNGLTFPEDGALYKDGQLVGKFSHDDQKIFNHESWTDFSTYENSIYH
                     SMYGLADLNNLNPTVDDYLKEAIDKWLEMGIDGIRVDAVKHMSQGWQKNWLSHIYEKH
                     NVFAFGEWFADGSFNDPLMTKFADTSGMSLLDFRFANSVRRLYSDLSAKMQDFYNMIV
                     ATEKEYKEVSDQVTFIDNHDMTRFATLVNHNQTAVNQAYALLLTSRGVPNLYYGSEQY
                     ATGANDPENRGDMPTFDKNSTAYQVISKLAPLRKKNQALAYGTTQQRWINDQVLAFER
                     KFGNDVALVAVNKDQTNGYTISGAKTALPAGKYADELGGLLGGKELTVSADGNVEAFE
                     LGAGQVAVWTFKGQHETPQIGDVDASFGVAGNTVSISGQGFGSAQGQLHFGDSKADIV
                     SWDDTLIQFKIPAVAAGNHDIKVTTSTGQSSSPYKAFEVLTDKQIPVRLVVNNFNTVL
                     GEQLYIVGDVVELGANDNHKALGPIFNATQSIAQYPNWFYDVNLPINKTINCHLVKKD
                     SSGKVLWTSPETYTIKTDSKAQTISLKK"
     gene            36048..37352
                     /locus_tag="TV188_000737"
     CDS             36048..37352
                     /locus_tag="TV188_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1534113.1"
                     /translation="MLKNEKMKNPQKAMWLSIIPGLGQLYNTQKVKGFILLLVFLGEL
                     LEAFFVGIPALAGLYSLGSVPMEDHSLFLLIKGAMQLILFALFLIFHLAAMRDARLVA
                     REINAGHSISLTLKEMVQSIYEKGFPYLLIIPAYLAMAFAIVFPVLVTLLIAFTNYDF
                     RHIPPYKLLDWVGIKNFKSILELSTFKSAFGSVLSWTLIWTLAATSLQIVIGIATAII
                     ANQSFVKCRRIFGVIFLLPWGVPAFISIMSFGNFFNDSIGAMNVQVLPFLEKFVPFAD
                     FGIIPWKTDPFWTKVAVIMVQGWLGFPYIYILVSGILQSIPADLYEAATVDGATALQK
                     FRQITLPMIFAVAAPTLISQYTFNFNNFSIIYLFNNGGPGTVGGGAGSTDILISWIYK
                     LTTQTSPQFSIASAVTLIISLIVISVSLITFKKFKAFDMEDR"
     gene            37353..38213
                     /locus_tag="TV188_000738"
     CDS             37353..38213
                     /locus_tag="TV188_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1534114.1"
                     /translation="MGRNYLPQSVKKKRLLAQLLTYSYLLILSIIILFPILVTVSSAF
                     RPGNTTAFSFHIDGPWTLSNFETLFQDTYYLRWYWNTLVVAFFTMLIQVTVITLTGYA
                     YSRYHFFGRQKSLVFFLVVQMVPTMAALTAYFVMAWLFNALNHYWFLILIYVGGGIPM
                     NAWLMKGYFDTVPYDLDESAKLDGSGHFRTFYQIVFPLVRPMVAVQALWAFMGPFGDF
                     MLAKFLLREQEHYTVAVGLQSFITNDARDPKVTLFAAGAILIAVPISVLFFFLQKHFV
                     SGLTNGGTKG"
     gene            38238..39068
                     /locus_tag="TV188_000739"
     CDS             38238..39068
                     /locus_tag="TV188_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein malA"
                     /protein_id="HEL1534115.1"
                     /translation="MTNDRFPISYTTIIFSPKMIFARCSAFLWWQNVILVIFLNALVL
                     MPITLHYASLKSYPLEHIVSNGLDSLTEKTYHALTQGTIWHDRYDGKTVLIEDTDAVV
                     AVLPTPEIVEELKKDQRSQLILTETSWILSFPDGQRLTAKVKGNKERLTRLTSLEAVK
                     AFVNQQWYNSNRAAVLAFLLLVASSVVYLGAGLVIGIGSLSLLLTRSARLFSLKSYSE
                     CLGLLVNCFGLPTLLAVLISFWVHNPIVIMNSQVFGTLLMLVLVFYKTQFRDEEQALA
                     "
BASE COUNT        10877 a         7381 c         9049 g        11789 t
ORIGIN      
        1 tgatagtgga aattatcact caagaagtac ggggtatcag agcaagactt attttaatct
       61 gagtaagctt cttgtcctta ggctcaagct gatcaggact gagtgaccac ccatttaaac
      121 cggggaacaa ggtagctaac gataatgctg ctaagtccaa taatggttag ccaataaagc
      181 cagctggaat caaagctaag cacgagatga cttccaagga caagcacaac accagaccaa
      241 aacaagatta gattaatcgg gttatcagtg atagtgacct gatcttgatt ggtcacgatt
      301 ttcttggcct gcctgctatg cttgatggtc aaataatcct cagcatcggg gagatcaata
      361 tcgatactct cacccggata aagcttaacc ttgtgggatt tcccgatatt aactgtcata
      421 ggtgctccta tctttgtcaa acgtgtcttg cgccttagct tcattcctaa aatcctctct
      481 aaaataaaag tcaagcataa tcatgccaat tccagccttc aaatgctaca aaagaccagt
      541 gtaccatagc ctatgatacc aaaaagcaga aagaatagcg actgtaaaaa atctgaaaat
      601 aagctttctt acatctattc cctgctttga aagcagactt ttgcaggatc tatgctagaa
      661 tagaaggaaa aggagggcac taatggttaa gggaataata tttgacatgg acggcgtttt
      721 atttgatacg gagccttttt atctcaaacg tcgtgaagcc tttttgacga gtaagggcat
      781 taggattgac cacctcagcc ccgaggattt tattggtggt aatcttcagc agatttggga
      841 caaggtctta gcagggcagg ctaatgctga tgaggcaaga gatattgctg tggcttatga
      901 ggcctataag ctgtgccata agcctcctta ccaagagctg atgtttaaag gggtcaagtc
      961 ctgcctcaaa gctcttaaag ggcagggact taagcttgct ttagcctcaa actctagtcg
     1021 ttgtgatatt ttgttagctt tagagagcag tcatatcaag gcttattttg accttacact
     1081 ggcgcgtgag gacgtcacag ctggtaagcc taatcctgag atttataaca aggttgcgca
     1141 ggctctggga ctggctaaag cagagtttgt cgttgtcgaa gatagtcaaa aagggattgc
     1201 cgcagctaag gctgctggct tgaaggttct agcaatcaaa gacaagcgtt acggcattga
     1261 tcaaggtcag gcagacaagc gcattgatag cctcaggcag ctatgtgagc tgcttaggta
     1321 aggcttctga tagagcagat gtttgttaac tgaaagatag caggctttat agtggcttat
     1381 catcactaca atagaatgat ttgtcttaga atgacagaac ctaaataggt gtttttctcg
     1441 tttttgtagc aggatagctg aagcttttga tctgctttat gtttggtgtt gttattaaga
     1501 gatgaaattg tcagtaatgt tgagcttact gataggaggg ctaatggcag ttaaattatt
     1561 aacagaaaga ttgatcatac aggagttgaa tgagacctat tttgagcctt atcacaaggc
     1621 atttaccgaa gaaatcacag catttcaatg gcctgatccc tttaaggaca tcgctgctgc
     1681 taaggagaca ctagctagct ttatcgcaga aatgaaaaaa ggaaacatgc tagagctagt
     1741 cattttgaat aaagcaaatg acttcgttgg aagcttggaa gtctttagcc ttgatagtga
     1801 gacaccggaa ttgggcatat ggttgaaaaa atcaagtcaa ggactaggct atggctatga
     1861 ggccttgaga gctattgtgg attatttaaa aggcaaaaac aaataccgtt atttcaatta
     1921 tgaggtagat gttagaaata ctggtaatat taagctggta gagaaattca atgtggtgac
     1981 atcgacctat caggaatgtg agacggcttc aaagaaaagg ctttgtttac aggtttatca
     2041 cattcttaat taatcgttgg tatgacatag gtgatagtca tggttttgct ttaagtcctg
     2101 tgtgagttga gagcagcttt cagctctagt atttgcttct ggtgtggtct tttagtccac
     2161 agtctaggta ttataaagaa gagatctggc tttgtttaaa aaacagcttc tctgtctgag
     2221 cttgtaccct caagatatca ttgaagagat agcaggacag ctgttgaaaa tgagggaagt
     2281 aagagggatc tgtgtgccaa gatcaaaagc ataaaaagcc tctagcttac ttcttgtggt
     2341 tagcattttt ttgaaagcat gctaatttgc ctttagtgtg ctttttgttt gctcaagatc
     2401 agctagtcaa tgaggccata gagtaagcct taacaaatgg tgagatgtag ctacagccgg
     2461 ttgtgcagat ggggttagaa taattggatc tactcacagc ctcttgtaat catttcctta
     2521 caaaaatcac actagtaaag acctctaatg gcgaaggagc tcctgacacc aagctctgaa
     2581 gaagctggct atttgtcctt gatcaaaaag ggttaagact gtcagttcaa ctaggtgcaa
     2641 acgactcata aggcaggtct ttagcagggg tgatgtcaaa aaattgacat cagctgtaac
     2701 cttttagcaa aattgtagtc caacaaaagt gagcagacat tttggaaggg ggacctgtta
     2761 ttggaatttg aagacatcta cttgatgtat aaagacgatg tttatccttt tcttcatgcc
     2821 tatgcgtgag acaacttatg acgaggttga accaagggct ttctttatag tataatggtc
     2881 gttaaagtga tattaataag aaagtgatga ctataatgac agaaatacca aaggatttaa
     2941 agctaaatac gattagtgtc tttgagcatt atcatattga tgtgtttgag gctggtcatg
     3001 tgctgttatc aacagagatc catgcgtcag ccttgaacta ttatggaaat gcacatgggg
     3061 gctttttgtt taccctttgt gatcaggttg gtggcttggt ggccaaatca ataggtcttg
     3121 aggctgttac tctgcaagct aatgtgaatt atcttaagcc tggtcatcta ggagaccgtt
     3181 tagtcgtaga aggtagtctg gtgcatagag gtcggaccac acagctgatt gaggtcacca
     3241 tcaaaaatca agatgataga ctattaacca gggttagcct gaccatgttt gtgacaagta
     3301 aaaaacgatc ctctgactag ctgatacaag tcatatcaaa aaacgtccag cttgatttta
     3361 gctggacgtt tggctttagc tgcgatagag cttatggtgc tgataaacag ggtcaaaggt
     3421 cacattgata ccgagctgtc tgagaacatg cttgtcctcg ttggtcagga taacggttga
     3481 atgcgcttcg ctgcccttga gatttcctaa ttctttcatg gctagatcgg cttggttgtt
     3541 gttcattgct gtgatagcca gcgccattag gatttcatta gcgtgtagcc tagggttgtg
     3601 actgcctagg tgattaatct tgagcccttg aatgggcttg acatattctg gctcaatgag
     3661 atgcgtttcc ttactaatgt gggccagtgt tttgatagca ttgatgataa cagcagcggt
     3721 cggaccaaac aaatcagatg ttttaccggt gactacctga ccatttggaa gctgaagggc
     3781 tagggcaggc tgaccagtta tctctgcttt ttgcctagca atgagagtaa cctgtcgatc
     3841 tttgggagtg acaccgatgt cattcatcaa gagctcaagc tttttaactg cagcctcggt
     3901 cacgcgctcc gctttgaagt ctaccaaggt ttgatagtag cggcgaatga tttcttgcct
     3961 tgaggcttcg atagcagcct cctcattaac aatggaaaag ccgaccatat taacacccat
     4021 atctgttgga gatgcatatg gggactggct taaaatacgc tcaaaggttc tgtttagtac
     4081 tggaaagacc tcaatatcac gattgtaatt gactgctgtt ttcccgtaag cctctaaatg
     4141 aaagggatca atcatgttca catcatctaa atcagcagtg gcagcctcat aggctaggtt
     4201 tacagggtgg tggagtggaa gattccaaac agggaaggtt tcaaactttg catagcctga
     4261 tgtgacaccc tttagttggt catgatagag ctgtgagatg caggtcgcta attttccaga
     4321 gccaggacca ggagctgtga cgacaatcag gttacgactg gtcttgatgt agtcatttct
     4381 ccccatacca tcaggagaaa tgatgtggtt aatatctgtt ggatagcctt tgattgggta
     4441 gtggcgataa gacgtaatgc catttttggc taattgcttt tgaaaatgat ccgcagctgc
     4501 ctgatggttg tactgcgtaa ttacaactga gccaacatag atatctaagg cgttaaaggt
     4561 atcaattaaa cggagcactt cctgatcgta ggagattcct aagtcaccac gcgttttaga
     4621 atgttcgata ttattggcat tgatggtgat gacaatctca acctgatcct tgagctcctt
     4681 tagcagcttg attttgttgt caggctcata gccaggcaag acacgcgccg catgaaaatc
     4741 ctcaagtatt tttccgccaa attccatgta gagcttgccg tcaaattgct tgatacgttc
     4801 tagaatatga ttcctttgta agcttaggta tttgttggaa tcaaaagcaa tgtttttcat
     4861 ttatttttca cctctgctaa gcattatagc aaagaaatag tgagaagtga atgatttgtc
     4921 taaaaattag tctcttcctc taagtagcta gggtggcaaa aagcagcgct atttaaatac
     4981 cgataaaaaa tgacttgaca aaggtgactg acttgcttat actaggaaca attaaatacc
     5041 actttaatga tgttctgtga ggcatgaaag tgacaagaca aagaggagtg agcctgctct
     5101 tattttgctg tagactgaat gcgactgatg gactggtgcc taggtctttt ttaatgggct
     5161 taaagggtat tcaattaatt aaggtagtca gtgagctact attaaaagga gaataatcat
     5221 gtcagcattg tctttagaca agaacaacaa gcgtgcgctt tgggctgcta ttgccgcttc
     5281 aggaacagat gatcttaacg ttatgtttct agccttttcg atgtcctcta ttatctctga
     5341 tctaggagtg agtagtactc aaggaggctg gatagctact atcactaatc taggaatgct
     5401 ctttgggggc ctgctctttg gtctgcttgc tgatagacat cataaattta aggtattcaa
     5461 atggacgatc cttatttttt cagtggcaac aggcttgatt tattttacca agacgattga
     5521 atttttatac ctcatgcgct ttattgctgg tattggggtt ggtggtgaat atggtgttgc
     5581 tattgcgatt atggcaggac ttgtccctgc tgaaaaaatg gggcgcgtct catcgctaaa
     5641 tgggattgca ggtcaggttg gatcaattgt ttctgcttta ttagcaggct ggctagcacc
     5701 tgctcttggc tggcgcggcc tctttctctt tggtctggct ccgattttac tagtcatttg
     5761 gatgatggtt gctattgatg atgataagat tattgataac catgtcaatg tttcagagga
     5821 agctagtcag ccggtaaaga ttagtgagtt atttaagaca ccagccttga caggacaaac
     5881 tctcgctttg atggtgatga cgacagttca gattgctggt tattttggta tgatgaactg
     5941 gctgccaact attatccaag ctagtctaca tatttctgtc aaggattcgt ctctgtggat
     6001 ggtatcaacc attgtgggca tgtgccttgg aatgctgacc tttggccatc tgctagatac
     6061 ctttgggcca agattggttt attctatctt tttgcttttg tcctctgttt gtgtctatct
     6121 ttttcagttt gccaattcga tgtcaaccat gcttattgga ggagctattg ttggattttt
     6181 cgttaatggc atgtttgcgg gctatggtgc gatgatcaca cgactctatc ctcatcacat
     6241 tcgatcaaca gctaataacc ttatcctcaa tgttggacga gctgttggag gcttttcatc
     6301 ggttatcatc ggtaaaattc ttgatgtttc aagtgtctct atggtcatgc tctttttagc
     6361 cctgctgtac cttgttagct ttgtggcttt gtggacaatc aaaaatctaa aggcagagcg
     6421 atatcaagcg ctgacaaaat agatctggta agtgtagtag gattagtagc aaaggttttg
     6481 ttaaagctct caaaaagcgc ttaggcattt agactaagcg ctttttgacc tttaaagctt
     6541 ttccaaaaag gcgtcttggt caaccctgac acgtgtgtgg caggctctgc caatgagctt
     6601 atggttggca aaggcttcga tacgaaagtc gtattttctg ccctcttcct tgagtgcagt
     6661 gataacaatg gttactgcct gaccgatttt agaggcagct aggtgctgga tagcgatttc
     6721 acttccaacg gttgtttgct tgtcctttag ctgactttgc agaaacgtga aggcagcatg
     6781 ctccataaag gcgacaagag caggtgttgc taggacctct aagccaccag agcccattgc
     6841 ttgagcagaa tgcttgcttt ttgtttcgta tagctgtgaa taaatagaca tgataccctc
     6901 cttttttatt attataatat attaagggct tacagtctta aatgagctgc cttttgtgct
     6961 atactaagaa ttagcttgaa agagctgttg ctgaattaat gtgtctcgca tgggccagac
     7021 taagcatcag ctaacagtaa gaagaagggg aatacatgcg cttagataag tttttagttg
     7081 atgctggctt aggcagtcgc agtcaagtga agctgctatt aaagaaaaag caagtcagtg
     7141 tgaatggggt tagccaaacg tctccaaaat atcaagtcaa tgaaatgacc gatgaggtta
     7201 gctatcaggg acaaaggctc aattatgagg cctttgtgta ttatatgctt aataagccta
     7261 aaggagtgat ttctgcgact gaggattcta gccataagac agtgctggat ttgttagatg
     7321 atactgcacg tcaaaaggct gtctttcctg ttgggcggct tgataaggat acgcatggct
     7381 tgctcttagt gaccaatgat ggaaagctag cacatgctct tttgtctcct aaaaagcatg
     7441 ttgccaagca ataccttgct gtggtagacg gtatgatgac tcaagaggac gtcaagcatt
     7501 tcgcacaggg aatcacttta aaggatcacc aatgcatgcc agcacatttg gacattcttg
     7561 agattaacga atcgctaaaa accagccttg tcaaaatcac catcgaggaa ggaaaatttc
     7621 atcaggttaa gcgaatggta gcagcctgtg gtaaaacagt cagcgattta cagcgcatta
     7681 gtatggggcc cttacagctt gatagtgctt tggcgcctgg agcctatcgt aggttaacag
     7741 cagcagagct agaggcctta aaagcctaag gctagactag tcactggctg ggttagctgc
     7801 tgaattgata gtaaaaaaga ccagtcttag actgatctgt agggtgatta gatcgcccat
     7861 tctcctcctc ggaagattgg aatgacttct ccgtctttgg taatgccatc gatatccatt
     7921 tgttcagaac caatcataaa gtccgcgtgg gctgttgagc gatttaggcc agccgcttcc
     7981 caaatgtgct gctcaggcat tccaagtctt aggtcagttc ctggtgccct gtagtgaagg
     8041 ctgtcaaact gataatcatt gaggagcctt gccttttttt ctaaacgttc ctgatgttgg
     8101 tcccaggcct tgacaggatc tgtctcgtaa atgcgattca ttttgaaaat ggcatcccac
     8161 aaagcgtcca cctgctcttc ttcgcttgtc aggtttggaa aaaccatagc agcccattcg
     8221 ggaccggctg cagctgctag attccagctg actttgttgg cctgagtggc agcccgctgt
     8281 ttttcaagag caatagctgt tgcgcgtgtt gctccagcta gcctatcaga atcaatatca
     8341 gcaaagacgt ttggattggc agagcgaatg actaagcggc ttgctttttg atcaaggaga
     8401 taatgtgact gttcaacgac ataatctggt acctgcaaga gacggtcttc atcagcctta
     8461 agaagcttct cgcgtgtgat ctgatcgtca ttatagtcaa caagaacctc agctgcacca
     8521 gcctcatagg cttttttggt taatagccgc gcaagcttgt gttgctctac tgcaatagaa
     8581 atgagtagtg tgtgaccttt ttgaatgttg actccttttt tgataagaag gttagcgtat
     8641 ttttcaagat aatcgtcaaa atgtggcaaa accatagcag tctcctaata tgttaatgtt
     8701 gcaaaattta atgtatcata tttgcgacta tttcacaagg agctagcctg tttcataggc
     8761 taaatgtctc ctagaatgcc tatcgtaaaa ggctcagtgt tggttttctc tgatgagtta
     8821 aaaaacgatc ccttttttga tcagtttgcg ctgcccttgc taatagatat ttgcttaata
     8881 gcgacattcg tgttaagata taagaggaaa aaatcaatag atgaggtatt taacagtggc
     8941 atttggagaa aatggacctc gcaaaaaaac tgcctttgaa aagttgacaa cagttgttgt
     9001 gatcgtgatg gttcttgtga ctgtcggtgg acttattgcg ggtgccctgt cagtattgat
     9061 gtaagaaaac gctgaaaggc gtttttttag gataagagaa ggtttgagaa gaaaagtatg
     9121 agtatgtttt tagatactgc taaggtcagt gttcaggctg gtcgtggcgg tgatggtatg
     9181 gtggcctttc gtcgtgaaaa atatgtgcct aatggcggcc cttggggcgg tgatggtggc
     9241 aagggtggct ctgtcatttt caaggttgat gaaggtttgc gtaccctaat agactttcgc
     9301 tacaatcgta agttcaaggc caaatccggt gaaaaaggca tgactaaggg catgcatggt
     9361 cgtggctcag aggatttgat tatctcagtg ccacagggaa cgactgtgcg tgatgctgaa
     9421 accggtaagg ttctgacgga tctggttgag catggtcaag aatttgtcgt ggctaagggt
     9481 ggtcgtggcg gtcgtgggaa cattcgtttt gcaacgccgc gcaatccagc acctgagatt
     9541 gctgaaaatg gtgaaccagg agaggagcgc caattagagc tagagcttaa gattttggca
     9601 gatgtgggac tggttggttt tccgtcagtt ggtaaatcaa cgctactaag cgtggtctca
     9661 tcagccaagc ccaagattgg tgcttatcac tttaccacta ttgtgcctaa tctaggtatg
     9721 gttcgaacca aatctggtga gagctttgct atggcagatc ttccaggctt aatcaaggga
     9781 gctagccagg gtgtggggct tggcactcag tttttgcgcc atattgagcg tacacgtgtg
     9841 attctacatg ttattgatat gtcagcagct gaaggacgag acccttatga ggactatgtg
     9901 gcgattaata aggagttaga agcatataat cttcgtctta tggagcgtcc gcaaattatc
     9961 gtcgccaata aaatggatat gccagaggca aaggagcagt tgcagcgctt caaggaacag
    10021 ttagctgctc agtatgatga ctttgaagaa ctgccaataa ttttcccgat ttctagcttg
    10081 gcacatcaag gcttggatag cctattagaa gcaacagcag agctattagc aaaaactgat
    10141 gatttcttgt tgtatgatga ggctgatttg gctgaggacg aggcttatta tggctttgcg
    10201 gctgaggaaa aggcctttga gattagtcgt gctgatgatg cagcttgggt attgtctggt
    10261 gagaaattag agcgtctctt tgtgatgacc aatctggagc gcgacgaatc tatcatgaaa
    10321 tttgctcgtc agctacgtgg catgggtgtt gatgaagcgc ttcgtgagcg tggtgctaag
    10381 gacggcgaca ttgttcgcat tggcaagttt gagtttgaat ttgtagacta atgacaaata
    10441 ccaagcttag ctgttttttg tagcaagtga tgctgagtca tatctgaagt aggctgtttg
    10501 ctcaattcac agcaatgagg tcttggttga tgtgagctag ggaggttttt tatgggagat
    10561 aaaccaatat ccttcaagga taaggacggt aactttgttt cggcagcaga tgtctggaat
    10621 gctgaaaaat tagaagaatt atttaatctc ttaaatccca ataggcgttt gcgtttggaa
    10681 cgtgacaaat taaaaaagga tgaagcttaa gtgcacttcc tctcaatcgt tagatttagt
    10741 gtctaacttt tgagggtgca cttcaaggct tcgtcctttt ttgatgcttt ttttcttggt
    10801 gatgctgcaa atgtagccaa ttaaaaaagg tgtaaatgtc attaacaaga aaggctgcaa
    10861 aacaaatgac cactgcgtat tggctggtat ttgcttgagc agcatagagc cacaggagaa
    10921 ttaagaccaa atcattaaga gcataggcca aggcaaaata agggctacgt ttgtagctta
    10981 agtaggctgc tgaaaaagag gtggcaatag ataaggtaga aacaggcaga taggctgtct
    11041 taagataggc taagatagca tagaacaagc tggtaactag tatggtaaga accactaagc
    11101 gcagccggtc tgctgttgtc aagcgtgaga tggttacctg agatgtctgg tcttcaaatg
    11161 ggtggcttag ccaggtaaac agtgacaaaa tagccatcgg cagggtcatg aagagatagg
    11221 ttatcagctc cccgtaataa ctgtttaata gtgacagata ggcataaata agggagaaaa
    11281 taatggccaa gctctgtcca atcggatttg ccttggcact aaagattaaa gctgtcacac
    11341 cgattaagga agctatcagt gctaagggag cttgttctcc aaagaaaaag gcactgagga
    11401 gaatagccga aatggaggtt aaccaaagcg tccactcggt ttttgtaaaa tagtttaaat
    11461 aagccatatc cttattcaag cataggcctt tttatctgtc aatagggtgt cgaccttagg
    11521 gaaaaataag ctaatacctg ccatagtgca attggttgtg aggcactaat actagcagat
    11581 aatggtgtta actagaggca aatgagctaa gagtttcctt attggctgct gctaatactc
    11641 cttgttgact ggtttagaag aaaaggacta agagccttag cttggctttg tcagttagtt
    11701 tccttgatga taaggaaaaa ctagattttt taaagcgttt acagtgtcct tttttcttcc
    11761 tataataggg gtataagtga caaaaagaaa ggaaaaagca tatgaagcaa tcaaaacgcc
    11821 gttaccaatt tccagaaggt tttttgtggg gaagctcaac atctggccct caaagtgagg
    11881 ggactgtttc tggagatggg aagggaccta gcaattggga ctactggttt agtctggagc
    11941 cagataagtt tcatcatcag attggtccag aggtaacctc aaccttttac accaactaca
    12001 aaagcgatat tgctctttta aaagagaccg gtcacacagc ttttcggacc tctattcaat
    12061 ggtctcgact gattccagaa ggggttggtc aggttaatcc aaaagctgta gccttttacc
    12121 gagaggtatt tcaggaaatc atggctcagg acattaagct gattgttaac ctctatcatt
    12181 ttgatctgcc ttatgccttg caaggaaaga gaggctggga ggctaaggag acggtctggg
    12241 cttatgagac ctatgctaag acctgttttg agctttttgg tgatttggtg gatacatgga
    12301 ttacctttaa cgaacctatt gttccagtcg aatgcggtta tttggggcat taccactatc
    12361 cttgcaaggt agatgccaag gcagctgttc aagtggctta ccatacccag ttggctagct
    12421 cacttgctat caaggcctgc cacgagttgt atcctaagca taggattagt attgtgctta
    12481 atgtgactcc tgcctatcct agaagtgatc agccagaaga tgtcaaggca gcgagaatcg
    12541 cagagctttt ccagactaaa tccttcctag atccgtctgt cttaggagtg tacccagaag
    12601 agttagtagt tcttttagag gcagctgatt tattgcccca gtatagtgct gatgaattgg
    12661 ctattatcaa aaacaatcct gttgatttct tgggagttaa ttactatcaa cctttgcgtg
    12721 tgcaagcgcc tagcaaaaca agacaagatg gtgaaccaat cacgctagcc tcttattttg
    12781 aaccttatga tatgccaggc aaaaaggtta accctcatcg cggttgggaa atctatgagc
    12841 agggccttta cgacattgct cttaatttaa aagagcatta tggcaatatt gactggttag
    12901 taactgaaaa tggtatggga gtagaaggtg aagaagcctt tttagttgat ggtcagatcc
    12961 aagacgatta ccggattgcc tttatcgaag accatttgat tcaattgcac agggctttag
    13021 aagaaggcgc gaactgtaaa ggctacctcc tgtggacctt tattgattgc tggtcttggt
    13081 taaatgccta taaaaatcgt tatggcttgg tagccttgga tttagagact caaaaacgaa
    13141 cccttaaaaa atctggccac tggtttaaga ccctgagtca gacaaatggt tttgataaat
    13201 aggagcgtat gatggtcacc ttaggatttt ccctttaccc tgagcggcat ggttttgcta
    13261 agagtaaggc ttatattgat ttactgcact gctatggagc caagcgcttg tttatgagcc
    13321 tcttacagtt ggcgccaaat gatcccaaga cctttaagtt ttatgcggat ctgattgctt
    13381 atgccaattg cttgggcatt cgggtcattg cagacgttag ccctgctttt atcaagcagg
    13441 ctggttggtc agatcaggtt attgaagagg ctcatgcttt tggcttagca ggcttgcgtt
    13501 tagatgaggc cttgccttta gaggatattg ttaggctaac gaaaaactct tttgggctta
    13561 agattgaact caatatgagt actgacaaga gtttattgac agccttgcta aaggcagctc
    13621 ctgatcggag taacctcatt ggttgtcata atttttaccc gcacgccttt accggcctgt
    13681 cactggagca ttttaaggaa atgtcccatt tttaccacga gcatgggatt gcaacggctg
    13741 cttttatcac agcccaatca gcaaaggaag gcccttggcc gctgtcagag ggcttaccga
    13801 ctgttgaggc tcatcggcaa ttgccaattg acgtgcaggt ggaactgatg aaggcgacag
    13861 gaactattga tactgtcatt ttgtccaatc aattcatcac tgaagatgaa ctcgttcagt
    13921 gccgtcaagc cttggataga tcagtcatgt ctattaaggt caagcctctg gttgatttga
    13981 cggacataga ggagaagatt atctgttacc cacattgtta tcggggagat gtatcagatt
    14041 atgtgattcg ctcaaccatg ccgcgtgagg tatatgctca agaagcaatt gctccaagag
    14101 agcagcccaa gcaggttaag cgaggcagta ttatcattga taatgaccgt tacaacaggt
    14161 acaagggaga attgcaaatt gcactcaaag cctttaccct tagctcaaag gccaatgtgg
    14221 tcgccaacat taaagaggat tacctaagcc tattagacga gttgaagccc tggcaggagt
    14281 tttcattggt gattgagact gactagtctg gcttcacaat cgatacggaa aatgatggtc
    14341 acttttttca ggaaacattt gctaaactaa gagagtaaag aaagcgtttt ctaaaagacg
    14401 aaggaggaat gatgctatca aaaaaagaaa tggctatagt agcatttcta atcagccaaa
    14461 aagggcagtt tgtctctagt gctaccttgg ctaaggctat tggcatgagt gatcgcacag
    14521 tcagaaaata cctaaaggag ctgattagca gccttcctag taagggagcg cacatcattt
    14581 ccaagcaagg tcagggctac tgtttagaga ttgatcattc tatggcgttt gagatctttt
    14641 ggcaggaaag cttggcctct aaaaagcgct tggctgatgt gactcaggtg gaagaaacag
    14701 ttgatcggga gcattatttg ctaaataaat tcttctttga agagcccgtt tgggattttg
    14761 aagagctctg ccaagaattg tatattagtc ggacgaccct aaaccatgtt ttagcggtta
    14821 ttagagaccg tattaggcct tatcagctac agcttgatgt gagtcatcag cgcgttcagg
    14881 tgacaggtaa ggaagaggct attaggcatt ttatcatgga ttattttttt gctaccagct
    14941 ttgatgactc catgtacgcc atagtagaca atacctttct tgatcatatc aagtttgctg
    15001 atatcacaat aattgtttta gatgaatgtc gagatgccaa actaaagctt tctgattttg
    15061 tcatgcacaa tttggttttg cacattgccc taatggttca gcgtattcgg tctggctatc
    15121 cgttagcatt tttttccatt ccagcagcta ttcgccaatc agacgagtat caagtggctc
    15181 tacgtatttt atatcgagta gaagaagtga tgggcattcg ttttcctaaa gaagaagcta
    15241 actatattgc tttacacctc aaggttaagc attccgttga tggcagccca caggacaata
    15301 aggccgatga cttgctgaga agtcatttaa aagcaggtat tgtcaaggct agtcagctga
    15361 caggtatgtc tttggaggct gatagcagct tgcttcaagg cctattggcc catatgaagc
    15421 ctttagccac aaggcttgaa aatcatattc agctgaccaa tcccttaact gaggagatta
    15481 aaagcaaata cccagaggct tttgccctga ctaagcaagc ttttgagaat attcctgagc
    15541 ttcaggctta tgacctgtct gatgacgaat gggcttacat tagcttgcat atcatggcag
    15601 ctattgagcg ctattccaat cgtcacaaac tgagggtgct tgtggtttgt gccacaggct
    15661 atggcagtgc catgatgctg aaaaatcgct tggaaaagga atttgaaggt cgctttcaga
    15721 ttgtagatgt tatcagctac tatgaaataa cacaggaacg actgcaaacg gttgatgtga
    15781 ttatttcttc tatcagcctt gctaatgtca tgtttttaac gccagtcatt actgtcagtg
    15841 tctttttatc tgatcaagac atcaaagcca ttcgccaatt tatcggggag caggagggaa
    15901 taagaagaga agctgcgtcg tcatcgcaga tgagcttgga aaaagcagag cagattctaa
    15961 aaggtgtctt tagtcctaag cgttttcttt atgtgaaaga aaaactatca aagaaggcct
    16021 tgctgttaaa gatgattgct tgtcttgacg aagcaatgga tgaagccttt gttgaggcct
    16081 tttatcacca aatcgtgttg agggaaaatt atagctcaat tgtttttggt gaggtgcttg
    16141 cctttccaca cccggctaat cccatgacct attctgaaca ggtggtggtg gctgtctgtc
    16201 aagagcctat tgactgggac gagagtcatc gggctgttca ctttatcttt ttgttgtcac
    16261 cgtccaaggg acgtaacagc tatttaaaat atatctcacc gagcttggtg tcttttgtca
    16321 atcaagcaga gcttcagcag gctttattag aagaaccaag ctatgcacaa ttcatcacat
    16381 tatttacccc actcatcact gaataaaagg agaagtatta tgaaaaccat tatgttagtt
    16441 tgtaatgccg gcatgtcaac cagtatgctg gtgactaaaa tgcaaaaagc cgctcaagcg
    16501 cgtggcatcg aggttgagat ttgggcagtt cctgtgagcg aagctgacaa tgaggttgct
    16561 gctaaaacca ttgatgtcct catgttaggg ccgcaggtca aattcttact aaaggacttt
    16621 aagaccaaat ttgaaccggc aattaaggta gatgtcatta acatggctga ctatggcctc
    16681 atgaatggtg acaaggtgct tgaaacagcc ctaacaatga tggaggaaga ggtatgacac
    16741 aatcatcaaa cctagaggcc attatgggat taatcatgta tggcggtgag gccaagggca
    16801 aggctgtaga agctattcat gcagctagag atggtcaatt tgaaaaggct cagcacttgc
    16861 ttcaagaggc tacacattct ttaaatgttg cccatagatc acaaaccaat ttgctatctc
    16921 aggaagcagc tggagatcag gttgatttgt ctttattgct ggtgcatggt caggatcata
    16981 tgatgacagc cttagccttt attgatttgg ccaaggaatt ggtcgctgtt tatgacaaaa
    17041 tatcaagaat ccaaagaggt gagctatgat gatgattaca gcagaaggag atgtctctgt
    17101 cactcaatgc ttcaaggcta tactaagctc tctccaagag gattatcatg aaaacaccct
    17161 gagacggctg ccaccagctg aattaaaagc agggctaagc tacataaagc attatggcaa
    17221 aagcaaggag cataacgtta gagtgctgat cacagcctta gaagctccgc acttatatgc
    17281 tgcttgcttt agctctaatc atgggctaaa aacattaagc taccgcttag aagctctggg
    17341 agagaagcgt accaaaataa cctattgcta cgactatcag ccacttgatg tctttcaaaa
    17401 agccaatcag ctgatcattg ggaagctttt taagaagagc ttcaaacggc aatcacaagc
    17461 ccaattggca gcccttatcc aatatgctaa gcagctaagc taggggaaga tttgagtaca
    17521 gattatctgg ctgattatag ggcttatcat actaaaaaat agaaacagga gaaaattatg
    17581 tcacattttt cggataagtt tatggagatt tcaggaaaga tgggatccca gcggcatttg
    17641 gttgccattc gtgattcctt tatttcgcta atgcccatca cgatggcggg ctctgttgcc
    17701 gtcttgctga atgttttctt gcgtgatatt ccaaacaata tgggctggac tggttttgca
    17761 gcagccatgc agcccattat tgacatcaat ggttatgtgt attttgggac aattggtatc
    17821 atggcactct tttttgcctt tgcttttggg tatcatttag ctcttatgca caaggtgaat
    17881 cctttggctg gaggtttaat ctcctttgct tcctttgtcg ccacccttcc tcaaagctta
    17941 accatttcca caccacttga aggggcgtca gcaagtttat tagcaggctt aaaggatatg
    18001 ggactatcag tggtcactgc aaatggagcc cgagttttag aaacaagcca gtggggagca
    18061 attgccctca aatatgctgg agcaacaggt ctttttacag cattgatcat tggcttttta
    18121 tctagctttg tttatgcgac tttgaccaaa cgtaacctga ccatcaaatt gccagataat
    18181 gtgccacctg cggttaataa ggcttttgcg gctattattc cagggacagt cgcgatttat
    18241 gtgtcagcga tcgtagctta ccttattttt gccctcacag gctcgtctct aagtgatatg
    18301 atttcgacct atatccaatt gcctttgttg gggctgtctc aagggcttgg ctctgttatc
    18361 ctgttaacct tcttggttca attgctctgg ttctttggtt tgcatggtca caatgtctta
    18421 gcacccgtgc ttgatggtgt gtacttagtg gctctaacag aaaatacagc tgcctataat
    18481 accagtcaga gcgttgctaa tctgccttat ctctggacga gaggctcctt tgatgcctat
    18541 gcacaaatgg gtggttcagg tgttactctg gctctgatta ttgctatctt tattttctca
    18601 aaacgtgagg agcacaagac cattgccaaa ttatcagcac cgatgggcgt gtttaacatc
    18661 aatgagccaa ttacctttgg tatgcctatt gtcttgaacc caacctttgc tatcccatgg
    18721 ctaatcgtac caccaatttg tgctagcatt gcttatgctg ccacagcaat aggcttgatc
    18781 cctcccgttt tcttgccagt tccttggatt acgccagttg gactttacgc ttacttggct
    18841 actggaggta gtgttatggc aggtctggtt tccttgttta acctctttgt tgcctttctt
    18901 atctgggcac catttgtcat gtcagctaat aaagaaaaag cgagtgacct ttcatgacag
    18961 caaaaaacgg agcaagcttt ttaatggcta taggattttt ccttattgcc attagtccaa
    19021 tggttggcaa caaataccta catatcgtga caggactagc ttttgttggc ttagggtatt
    19081 atctcactaa gcgcaagcgt ccttagtcaa tgcgagcagc tagcccctat gaaaagacaa
    19141 acctaagggc tagccttgat tttctatctt ggttatcgca tttaaaagca agcaaaaaag
    19201 caagggtaga tgcttacctt tgcttttttt attttttgac ctttaataga atatcttgct
    19261 acttaaacat ttaagacctt atctaaaaat tcaattaagc gtgggtgctt agggtgatca
    19321 aagatttcct ctggagtacc gtcctctagg aattggccgc cgtctgtaaa gatcacacga
    19381 ttagccactt gacgagcaaa gcccatttca tgtgtcacaa tcagcatggt catgccctgc
    19441 tctgctaggt ctttcataac gtttaagacg tctccaacca tctcagggtc aagagcagag
    19501 gtaggctcat caaagagcat gatatcaggg ttcatggcaa gacttcttgc aattgcaaca
    19561 cgctgctttt gaccacctga tagacttcct gggaaagcgt cagccttatc agctagaccg
    19621 accttctcta gaagagcaag tcccttttcc ttagccgcct cctttgagac ctttccaagc
    19681 tcaactggtg caaaggtaat gttatcaagg actgtcatat gtggaaagag attgaagtgc
    19741 tgaaacacca tgccgatatt ttcacgagcc ttatcaatat tggtattagg atctgaaagt
    19801 tcaaagccat caaccacaac cttaccacta gtaatggatt caaggagatt gagggtgcgc
    19861 aggaaggttg attttccaga gccagatggc ccgataatac aaacgacatc accctcgtaa
    19921 aatttagcat taatgccttt taagacctca ttttgcccat aggatttgtg taaatcttga
    19981 acatcaattt ttaattctgc cattagttaa gcctcttttc taaacgtttt gcaagccttg
    20041 ttaagagtgt aatcataatc aagtagataa ctgctaggat agcatacatg cggaaggatt
    20101 gatagtttct agcgataatg attttccctg tttggaagag ctccactaaa ccgatcgctg
    20161 agactatggt cgtatccttc aaggaaatga caaactgatt gatgaagttt ggcagcatta
    20221 gcttaatggc ctgaggaagg ataatccttc gcattgttgt gtgatatgac aagcccaagc
    20281 tgcgactagc ctccatttga cctgccggca cagcctcgat acccccacga acaatttcgg
    20341 caatataggc tccaccattt agcgaaagtg caatagtagc agctacaaaa tcgttaatcg
    20401 gtgattgatg cccagtcatg ctttcaatga ggtttggcac tccccagaag ataaaggcag
    20461 caacaatcat caaggggata ccacgcacca catcaacaaa gatagtagaa gccatgcgca
    20521 ggttctttga tggggataca gccatcattc caaaaacaat accaataacc aaagcaatgg
    20581 caaaggagat gagtgtcaga ccaagggttg ttccaagccc agccaataat tgcttgtagt
    20641 tattagctaa aagtccataa atagttgact catcggctgt tttgacagat gcctctgaat
    20701 caaggtatct gctgatgatg gcgtcgtatt ttcctgatgc tttaagagca gccaaaccgt
    20761 tgttaaacat ttcgatgagc tcagggttgg ctcctttttt aacagcaaaa ccatactcac
    20821 cagaaggctc tcccttgata ggaatatcaa gcttgtggcc tcgctgaata gcgtacctta
    20881 aaatagcttc atcatccata agcccgtcaa tagaaccaga atttaagcta tcgtacattg
    20941 aggaggcctc atcaaaggct tttagacggt aaccataaat atccttgttg ctttcaagga
    21001 aatcatagga ggctgttcct tttttggcac cgactatttt acccttgagg tccttgtatg
    21061 atttgataga gcttccggat ttgaccccaa ggcgaatgtt tgatgtgtag taggaatctg
    21121 aaaaatcaaa aatctcacga cgtgcaggtg tgatagacat acctgcaata acagcgtcag
    21181 cctgaccagc ttgaacagca tttaaagcag cgtcaaagcc aggattgctg atctcaatgg
    21241 taaagccttg ctgcttagca attgccttga tgaggtccat atcaataccg acatattctc
    21301 cgctgccaat ttgaaattca aagggagcaa aggaggagtc agccacgatt ttataaaccg
    21361 gctttaaagg agtggcctta gcagaggcat cgccagtagc cttgcctgct gtgaccttgt
    21421 cattgctgcc aagccatttt gtcatgatag cttgataggt tccatcagcc ttcatagcgc
    21481 ctaaggcttc attgaagtcg tcaatgagat aatcatagcc gctgcctttt ttgacagcaa
    21541 agccaaagct tccaatagcc tctcccttca tgttgatcgc aagatcctgc ttttggttaa
    21601 tggcatattg aatgacaggc tcgtcgtcca taacagcgtc aatagagcct gttgcaagac
    21661 tgttgtacat caggtcacct gtgtcaaatg ttttaacagt ataaccatac gattttttgt
    21721 atttatctaa gaaggcttga gcagctgttc catttttaac accgactgtt tttcctttta
    21781 gctcgctata tttcttaata gggttagcct ttcttgtagc aataacaatt tttgtatcgt
    21841 aatagggatc tgaaaaatgg aagacctttt gacgagcagc agtgatggtg gtgcctgcca
    21901 taagggcgtc agcttgacca gactgaatgg cattgacagc agcatcaaag ccagggaatg
    21961 tcatattgat attccaaccc tttcgctttg ctacttcatt gatgatgtca acatcaatcc
    22021 ccttatacac ctgatctgaa tccttgaatt caaacggtgc ataagcagta tcagaaacaa
    22081 tatcaattgt ctctgcactt gcaatcccag cagtcatcaa aacaactgac agcattgcaa
    22141 gcatccatgc ttttaatgtg tttttcatac tagtctcctt aataaaaata aaaaatatgc
    22201 ctaattatag cagatttttt tcaaacaagc aaatcatctc ttctttttat gtcataaaac
    22261 ctaacataaa caactaaaat agtcaaaaag ctttgataga gtctttaagt ccttaactat
    22321 gttacaatag ataagagata agatattgag gaccaataaa tgattgataa acgtgatttt
    22381 aaagcattta agctcgtgtc aaaatatgcc ccctcaggag atcagccgca ggcgattgag
    22441 accttggttg ataacattga aggtggtgaa aaagcgcaga ttttactagg agcaacagga
    22501 acagggaaaa cctataccat gagtcaggtg atcagcaagg tcaacaagcc aacgttagtg
    22561 gttgctcata acaaaacctt ggccggtcaa ttgtacggtg agtttaaaga gttctttcct
    22621 gaaaatgctg tcgagtactt tgtatcctac tatgactatt atcagcctga ggcctatgtt
    22681 ccttctagtg atacctatat tgaaaaagac agctctgtta atgatgagat tgacaagctg
    22741 cgccattcgg ccacctcatc gcttttagag cgtaatgatg tgattgttgt ggcttcggtt
    22801 tcttgtattt acggattggg ctcaccaaag gaatatgctg attcagctgt tagcctgcgt
    22861 cctgggcagg agatatccag ggatcagttg ctcaatgccc ttgtagacat tcagtttgaa
    22921 cgcaatgaca ttgattttca acgtggacgc tttcgtgtgc gtggtgatgt ggttgaagta
    22981 tttccagcct caagagatga gcatgccttt cggattgagt ttttcggtga tgagattgat
    23041 cggattcgtg aaattgaaag cctaacgggt aaagtattag gtgatgctga tcatttagtg
    23101 ctttttccgg ccactcactt tgtgaccaat gatgagcaca tggagcagtc tattagcaag
    23161 attcaggcag aattagcaga ccagcttaag ctatttgaag cagaaggcaa attgctagag
    23221 gctcagcgcc tgcgtcaaag gacagaatac gatattgaaa tgctacgtga aatgggctac
    23281 accaatgggg ttgaaaatta ctcacgtcac atggacgggc gttcggcagg agagcctcct
    23341 tataccctgt tagatttctt tccggatgat tttcttatca tgattgacga gagtcacatg
    23401 accatgggac aaattaaagg catgtacaat ggagacaagg ctagaaagca aatgcttgtg
    23461 gattatggct ttcgtcttcc gtctgcctta gacaatcgtc cgcttcgtcg ggaggagttt
    23521 gaaagtcatg tgcaccagat tgtctatgtc tcagcaacgc ctggagatta cgagatggag
    23581 cagactgata cgattgtgga gcagattatc agaccgacag gtctgcttga tccggaggtt
    23641 gaagtccggc caagcatggg acaaatggac gacttgcttg gcgagattaa cctgagggtt
    23701 gaacgaggtg agcgcacctt tatcacaacc ttaaccaaga aaatggcgga ggatttgacc
    23761 gactacctca aggaaatggg tgtcaaggta aaatacatgc atagcgacat caagacatta
    23821 gagcgtacag aaattattcg cgaccttcgt ttaggcgttt ttgatgtctt gattggtatc
    23881 aatctgctgc gtgaaggtat tgatgttccg gaggttagcc ttgttgctat tcttgatgcg
    23941 gataaggaag gcttcctaag aaatgaacga ggtttgattc agacgattgg tcgagctgcc
    24001 agaaatgctg atggtcatgt gattatgtat gctgatcgta tgacggattc catgcagcgc
    24061 gctatagatg aaactgctcg tcgtcgtgcc atacagatgg catataatga agagcatggg
    24121 attattccgc aaaccattaa aaaagatatt cgtgatttaa tcagtatttc cagagcagtt
    24181 gaagcaaaag caacagaagc agagacaaat tatgagtcaa tgacgcggtc tgaaagacaa
    24241 gaagctatta agcaattgca aaaaaacatg caggaagcag cagagctgct ggattttgaa
    24301 ttagcagcac agcttcgtga cctgatctta gagttaaaag caatggatta agacctgata
    24361 agctaagtct ggctgtataa gctaggcttt ttatctgctt ttgagtttgt cctttaggtc
    24421 tgtcttatga tctttggtac cagataaatg agtgatatct tgagcttgat ctacgcaaga
    24481 gctagtgcag ccactagctt cagactactt taatgattta atgaaagatt gattttgata
    24541 agacaattct gatataatgt aaagtagttg gcaaaaatag aaacattaaa taaattttct
    24601 ttttaataat ttaactttta ccttgtcaac aaggctattt tcggatagaa tttcttagta
    24661 cattatttca ctaatacaag aaggtaagta tgttaaaaaa caagtcaaga ctgcgagcta
    24721 ttttcgtttt tgttgggaag atagcgttgt tttacgtgat tttgatgctg ctcgtttatt
    24781 tttttggtta cctagggcat ggtcaaagta attttattta taatgaattt taggagattg
    24841 tctgatggtt aacgatatga ttgaaacaat tgagtatttt gcacaagcac aaccggattt
    24901 tccagtttat gattgcttgg gagagcgccg tagctatggg cagctaaagg aggactcaga
    24961 tagtattgca gcccttattg agagcttaaa gctaggtgaa aaatcacctg ttttagtttt
    25021 tggggctcaa agctatgaca tgctggcttc ctttgtcgcc ttgacaaaga caggtcatgc
    25081 ttacattcct gttgatgttc attcggcgcc agagcgtgtc ttgtctatta ttgagattgc
    25141 tcagccaagt cttatcattg ctattgagga gctgccggtt agtattgatg cgattagggt
    25201 ggttagctta gcagagatag aggcagctaa agcagccaag gcagccttta ccatgaccag
    25261 tcctgtcaag ggagatgaca attattatat tatcttcacc tctggaacga caggacagcc
    25321 aaagggagtg caaatttcgc atgccaatct tttaagcttt accaattgga tgattgagga
    25381 tgctgagttt gctattcctg agagaccaca gatgctggct cagcctcctt attcctttga
    25441 tttgtcggtg atgtattggg cgccgacctt agctttaggt gggacattgt ttgctttacc
    25501 caaggaaatg gtttcagatt ttaagcgctt gtttagcaca attgcggagc tgccgatagg
    25561 gatttggacc tcaacaccgt cctttgccga catggcaatg cttaatgatg atttttgtca
    25621 ggagaagatg ccaaggctga cccactttta ttttgatggg gaggagctga cagtatcaac
    25681 tgcaagaaag ctatttgaac gctttccaga cgcacgcatt atcaatgcct atggtccaac
    25741 agaggcaacg gtggcgttat cagcgatttc aatcactaaa gatatgatag agacttacac
    25801 acgcttgccg ataggctatc caaagccgga ttcgcctact tatatcattg atgaagctgg
    25861 caatgctctg gagccggggc aacagggaga gattattgta acgggtccag cagtttctaa
    25921 gggttatctc aacaatcctg aaaagacagc tgaagccttc tttaccttta atggcatgcc
    25981 tgcttatcat acgggagatt taggatcatt tactgaggac aatgtgttac tttatggtgg
    26041 acgattagac tttcaaatca aatatgcagg ttaccgcatc gaattagaag atgtgtcgca
    26101 gcagctaaac caatcaccgc tggttgaatc agcagtagca gtaccaaggt ataacaaaga
    26161 gcataaggtc caaaatctct tagcttatgt tgtcttgaag gacggggtga gggagcaatt
    26221 tgcgagagat ttggatatta ccaaagccat taaagcctct gttaaggatc atatgatggc
    26281 ctatatgatg ccgtctaagt ttatttatcg tgaaaagctc ccattgacac caaatggcaa
    26341 aatcgatatc aaattcttga ttaacgaggt taatcatcaa tgacgacctt gtttcatcac
    26401 ataccttata tggagcctta tggcaatccg atttattttg tctacctcat cattgctttt
    26461 cttccagtta ttattgggat ctttaagcaa aggcgttttt cgacgtatga aagctttgtc
    26521 agcctgatct ttattttgct catgtttggt ggagagcact atcagcaatt gcttgccttt
    26581 ttagcctatc taatttggca aaccatcagt gttttggctt acaagcacta tcgtcaaaag
    26641 gcaaatgcag cgtgggtttt ctatcttagc attttagcca gtctatttcc tttgatttgt
    26701 gtgaaggtaa gcctcagtct aacgaggtct ttctttagct tcttaggtat ttcctattta
    26761 actttcaaaa gcgttgggat gatcattgaa atgcgtgatg gggttttgac agattttagt
    26821 ctaaaggatt ttctacgctt tatgattttc tttccgactt tttcaagcgg gccgattgat
    26881 cgcttcagaa ggtttcaaga ggcttacacc aagcttccta gtcgtgatgt ttaccttgat
    26941 atgctcaata aggctgtcat gtatctcatg ctgggctttc tgtacaagca tattatctct
    27001 tattgcttgg gtgggctgct attgcccctt gctgaaaata aggctctgac tgtaggtggc
    27061 tactttaata aagagacgat ctatgtcatg tacctttatg ggcttaatct cttttttgat
    27121 tttgctggct actcgatgtt tgcgattggg ttgtcttatt tactggggat taagacacct
    27181 gaaaatttca ataagccctt cttatcacca aatttaaaag agttttggaa cagatggcat
    27241 atgagcctat cattttggtt tagggatttt gtttttatgc gattggtcca tctattgatc
    27301 aagcacaaga cctttaagaa tcgaaatgtg acttcgggct ttgcttacct gatcaacatg
    27361 ctggtgatgg gactttggca tggcttgacg tggtattata ttgcttacgg tctgtttcat
    27421 ggtattggct tgattgtaaa cgacgcttgg cttcgtaaga aaaaggaaat caatcgtcgt
    27481 cggaaaaagc aagggcttaa gcctttgttt gagggtaagg tatttcatgc tttatcaatc
    27541 gtggtcactt tccacgttgt cttgttctca cttctgttat tctcaggctt cttaaatgag
    27601 ctttggttta gcagaccgtt acgttaaaaa aggagagtat aaaaatgtct actaaagaaa
    27661 ctgtaattga cttatttgat cgcttgttta tggaagacgt atcagatatg atggacgagg
    27721 atttgtttga tgctggcgtt cttgatagcc taggaacggt tgagctgatt gtagagatcg
    27781 aatctatctt taacattaag gtgccaattt cagagtttgg acgtgaggac tggaacactg
    27841 ccaataaaat tattcagggc atagaggaat tgcagcatgc ttaaacggct ttggttaatc
    27901 ctaggtcctc taatcatcgc ttttggcttg gtttgtctta ccatattcag ctttcctact
    27961 aagcttagct attcattgcg ccaggaaaag tcaaatgcag tggcaatcaa tgatagctcc
    28021 tttaaaaacg gcttgattaa aaggcaggcc ttgtcagatc ctaactactg ttttgttccg
    28081 ttttttggct ctagcgaatg gagtcgcatg gatagcatgc acccatcagt gcttgcagaa
    28141 cgctacaagc gctcctacag accgttttta attgggaaaa gaggctctgc ttccttatca
    28201 caatattacg gcatgcagca gatttcacag gaaataactg gaaaaaaggc agtctttgtc
    28261 gtgtccccac aatggtttac cccccaaggc attgatcctg gtgcggttca attgtatcta
    28321 tctaatagtc aggtgattga tttcctctta aaagcaaagg ctagtcataa ggaatcacaa
    28381 tttgccgcta aaagaatgct ggacattaat ccgggagttg ctaaatcaga gcttttaagg
    28441 aaaattagtc aaggcaaggc cttgagtaga tgggacattc gtctgctcaa atggcagcag
    28501 gagctgtcct taagagagga gtccttgttt agcttccttg gtcgttcaac aaactatgag
    28561 gataggattt tgcctcgtgt taaagggttg cctaaaacct tttcttatga gcgcttgagc
    28621 gagctagcag ccagacgggc taaggaagga acttcaaata atcgctttgg catcaaaaat
    28681 gctttttatt ctaagcgaat tgcaccgcaa tttcctcttt ataagaattt tcagtgccgt
    28741 aataattaca ctgtgtcacc tgagtacaat gattttcagc tggtattgtc agaatttgca
    28801 aaacgtaaaa cagaggtgct tttcgttatt acacctgtta atcaagcgtg ggcaaattat
    28861 acaggcttaa accagaggag gtatcaaaag gctgtcagaa aaataaagca tcagttaacc
    28921 tcgcagggct ttactcgcat tgctgatttt tccagaaatg gcggagacaa gtattttatg
    28981 gaggatacca ttcaccttgg ctggaatggc tggctagcct ttgacaagga ggttgttcct
    29041 ttcttagagg atcaaacacc accatctgaa taccaactgg atccttactt cctatcaaag
    29101 gactgggcag atagaacagc aggattttag ggtcaataga ccattagaaa atgaggatta
    29161 gaattgttaa tgagtatcat cgtcatattg cttattttag ccattgctgt tttagtgatt
    29221 gagtatggtc aaaagcggtc cttttctagc tggctgcttg aaaagatgtt tgattatcgt
    29281 aagtataagc tctctaaaaa ggctgatgac tatgaaggaa ttgagacgca aagacgtcgt
    29341 cgcattccct accacttgga taatccagag gcggtattgg ggattcccac cacagaatat
    29401 acgattgatg gcatgcaggt ttttgtgatc aatgaccaag attctcagga tcagccagtg
    29461 atttactatc tttatggtag tgtctatttg cgtcgacctg agacatttca ctttaaaacc
    29521 attaagcatt tgatccattt aaccaatgcc aagctggtgt tcccaaattt tgagaaggcg
    29581 ccttatgtca cctataagga gatttaccca aagcttgcta aaacttatca ggagctttgt
    29641 ctagccaatg gcgctgccaa ggttagcatt attggtgact cctcaggtgg tggcatggcc
    29701 ttagccttgg cgcaatacct aagagatacc caaactgcac cacagccaaa gcaattaatc
    29761 ctgttatctc cttggttaga tgttagcttt gctaatcagg attataagca ttttgaagca
    29821 gtagaggctt atttagatgc taggcggctt cgagacattg gtgaattgtg ggcaggcagt
    29881 ccagaagaaa tgcggtctcc gtatgtcagc ccattatatg gcgattatca tgacctgcca
    29941 aagattgtca cttttgtcgg gacaaaagag attttttacc cagatattat gaccctgcat
    30001 gagcgcttga tggagcaagg gcacttaaat cagctcgtta ttgctgagca gatgattcat
    30061 gcttatgcga tcttcccgat acgagaggca aggcaggcgc gcaagcagat tgccgagctg
    30121 attttaaaga aggagtgatt gttgctatag gagtcagtta gccttgcttg tctgatgagg
    30181 cttgggcttg agatttctag agaagcttta aggcctttac ttgggctgtt aatgctcatt
    30241 aaagaggatt ataggcttta tactagggct taggattgct gttttgctat tcaataatat
    30301 tagtttagac ttgattgagg aaaggctagt tttagttatg gtcctcaatc tttttttgat
    30361 ggtaaacatg tcaagacagt ttacttgcta gggtaataat cctgtgctca tttcatgagt
    30421 ggctattttt atcctaagct tggtggtgga aaaatcagat taaaaaatat gaaatttgct
    30481 attgacagct gtaagcgatt gcattataat aaacttaact taaacgttta agttaagttg
    30541 aataagctga tttgatcatg cactgcctaa atgcaatcaa taatctcaaa gcatttggtg
    30601 tagtctagta atcaatgagg cagtttatta cggttataca atatttattt agttcatccc
    30661 tttaggaggt aaatagctat ggcgtgggat tggaaaaaag caggtgttgt tggagtagtg
    30721 tcattggctt cgatcatggt attaagtgct tgtagcggag gacatcaaaa agaggctaag
    30781 caaaaagacg acaataccat tgtagtttca gttgatgagg gctatgcaga ctacatcaaa
    30841 gagattaaga cagcctttga aaaggacaat aaggtcaagg tcaaggtcaa aaaggaaggt
    30901 atgattgata cgctagataa gctatctact gatggaccga caggtgcttc accagatgtc
    30961 tttttagcac catatgaccg ggttggtggg cttggctctg aagggcaaat tgctgaggtg
    31021 agcttaggca atgctgacca gtttgatgac actgttaaaa agctagtcac cataaatgga
    31081 aaggtttatg gggcaccaga tgttattgag accttagtga tgtattataa caaggatttg
    31141 gtatcagagg ctccgaaaac ctttactgac attgaagagc taaataagga tcctaagttt
    31201 gcctttgctt ctgaagacgg taagtctgta ggctttcttg ctaagtggac agacttctat
    31261 tatggctatg gcttgattgc aggctatggg gcttatgtat ttggagataa gggaactgat
    31321 ccaaaggatt taggtattgg taatgctggt gccattgaag gcttagacta tgctaagaaa
    31381 tggtatagcg tatggcctca aggcatgcag gatactcaaa aggctggaga ttttattaca
    31441 gagcaattca cctctaaaaa ggctggtgtg attattgatg gaccttgggc tgctgcctca
    31501 tttaaggagg ctggtgtaaa ctttggagtg gcacaaattc caagcttacc taatggcggt
    31561 agctatcaag cctttggtgg tggtaaagca tgggtgattt caaattattc taagaataaa
    31621 aagctggcac agcaattcct tgattatgtg acaaatgaga aaaaccaaaa agccttttat
    31681 gataagacac aagagatccc tgccaatcta gctgctcgca gctatgctgc agaacaagga
    31741 aatgaattga caaaggcggt tattgggcaa ttctcaaatg ctcagccaat gccaaatatt
    31801 ccagaaatgg cagaagtttg gggaccaggt gcgaacatgt tctttgaggt agcagcaggc
    31861 aagaagactc ctgccaaggc tgctaaggaa gcagctaaaa ccattcaaga ggctattgca
    31921 caaaaataca ctgaataaca taaaaaggga ggctgggata aaggtatcct agtctccatc
    31981 ttgttaccta tagtatcaga gtgggcgatg aggagataat aataaaaagt agtagtgact
    32041 agcttgtctt gtttcccatc ttgtcctaat aagagtatct gataagactg atgaacctag
    32101 ggaggaaaaa atgaacacag ccggaatact gcatattcca gattctagat attgctttgc
    32161 cttatcaaca aaggagcttg tgattcggtt gagggttgca aaggaggata acgatatagc
    32221 ggtgacgctg gtttatggac ctaagtatca ttatcatgag tatcaaaaag aactggcgat
    32281 gtatgctgct tataccgatc atacccatac ctattatgaa atcaccttaa gtcttgatga
    32341 tgttagattg gcctatattt ttaagcttga gcaatctggt cacacctatt actttagtga
    32401 ggatggcttg accacaagct atgatttttc aaatggcttt tacaactttt ttcaaatgcc
    32461 ttatattaat gctgtagacg ttcatcagac tgtcccttgg gtgcacaatg ctgtttttta
    32521 tcagatcttt gttgatcgct ttcatcgtgg tgactttgaa aaggacgata gctatattaa
    32581 tatggcttgg ctggataggc caactcctaa tagctttgcc ggaggggatt tgaaggggat
    32641 tacagataag ctggaatacc ttgaggatct tggtattaat gtcatttact tgacaccgat
    32701 tttcaaatcc atcagtaatc acaaatatga tattagtgac tactatgcta ttgacccgat
    32761 gtttgggaca tcgcttgatc tccagcaact aataaacgag gcccaccaaa gagggattag
    32821 aattatttta gatgctgttt tcaatcatgc tagcagtgat tgcgagccat ttcaggacgt
    32881 tttggcacat ggtagtgctt cttcattttt tgattggttt atgattcaag gagatcatcc
    32941 ttctgtagag ctagctaatt acgaaacctt cgctgattgt cactacatgc ctaagtggaa
    33001 tacctcgcat caggctgttc aggattattt gattgagatt ggtctttatt ggatcacaga
    33061 gtatcatatt gatggctggc gattagatgt ttctgatgag gtatcgcatg atttttggag
    33121 acgctttcga aaggctgtta aggcagtcaa atcagatgcg atacttattg gagagaattg
    33181 gcatgatgct tatccctacc ttcaaggaga ccagtatgat ggtattatga attacgcctt
    33241 taccaaggct tgtctcgatt attttgcatt tgatgcgatt agctcacagg aaatggctga
    33301 aagattgtcg catattttaa tgagaaatac ttggcaggtc aaccagatga atctgaattt
    33361 actggattcc catgatacgc atcgcttctt gactcaggtg aatggctcta aggacaaatt
    33421 attggctggc ttagcccttt tagttacctt tatgggcata ccatgtattt actatggaac
    33481 agagcttgcg atggagggag gttatgatcc tgactctaga cgtagcttta attgggacag
    33541 cagcacttgg gatatgagct tttggaatca ggttaaggac attatcagcc tgcgtcgtca
    33601 tgcggttatc caatttggaa gcatttcgat aacctcccat gatgactgcc tttgcgtaaa
    33661 gcgtgaatta aacggtcaat cgataagatt gctggttaat aatggcgtta agccatatcc
    33721 tattgagaaa ggaggttctg tgcttgtttc taatggtgta gataaagaga catttgagct
    33781 actccagaac gggtttgttg ttagctatta atatggcgtt ttatcaaagg aggttaagga
    33841 tgaagcgtat tactttaaca tgtcgtaaag cattaacagt agctatggca gcggttacct
    33901 tagcaatgtc aactaacagt gtctttgcta ttgaaaatac tgcggtgtct aataaggctg
    33961 atttttctac tgacacgatt tatcaaattg tcaccgatcg ttttcatgat ggtaatgctg
    34021 ctaataatgg aaatacagat gtatttgata aaaatgatcc taaaaaatat catgggggtg
    34081 attgggcagg tatcattaag aaactagaag atggctactt aaccaattta ggggtatcag
    34141 ctatctggat ttcatcacca gttgaaaaca ttgataccat tgacccttca aatggcagtg
    34201 cagcctatca tggctactgg gcaaaggatt ttttcaaagc aaacagtcac tttggaacaa
    34261 tggaggattt taaaaagctc attcaggtgg cacatggcaa aaacattaaa gtagttattg
    34321 attttgctcc taatcatacc tcaatagcag aatataatgg cttaaccttc cctgaggacg
    34381 gtgctttata taaggacggc cagctggttg gtaaattcag tcatgatgat caaaagattt
    34441 tcaatcatga atcatggact gatttttcaa cttatgaaaa tagcatttat cattccatgt
    34501 atggcttggc agacttgaac aatctgaatc caacagttga cgattatctc aaagaggcta
    34561 ttgataaatg gttagaaatg ggcattgatg gtattcgtgt agatgcggtc aagcatatgt
    34621 cacaaggctg gcaaaaaaat tggttgagtc atatctatga gaagcataat gtattcgcct
    34681 ttggggaatg gtttgctgac ggttctttta atgatccatt gatgactaaa tttgctgata
    34741 ctagcggcat gagcctgctt gattttaggt ttgctaattc tgttaggcgc ctgtattctg
    34801 atttatcagc gaaaatgcaa gatttttaca atatgattgt agctacggaa aaagagtaca
    34861 aggaagtttc agatcaagtg actttcattg ataaccatga tatgacccgc tttgctactc
    34921 tagtcaatca taatcagaca gctgttaatc aagcctatgc tttactgcta acatcgcgtg
    34981 gtgttccgaa tctttattat ggttcagagc agtatgctac aggtgctaac gaccctgaaa
    35041 atcgtggtga tatgccaacc tttgataaga attccactgc ttatcaggtg attagcaaac
    35101 tagcaccact gcgtaagaaa aatcaagccc tggcttatgg tacaacacag cagcgctgga
    35161 ttaatgatca ggtcttggcc tttgaaagaa aatttggaaa tgacgttgct ttagtggctg
    35221 ttaataagga tcaaacaaat ggctacacaa ttagtggcgc taaaacggct ttaccagctg
    35281 gtaagtatgc tgatgaatta ggtggcttac tgggcggaaa ggaattaacg gtatcagctg
    35341 atggtaatgt tgaggcattt gagttaggtg cgggtcaggt tgcagtttgg acctttaaag
    35401 ggcaacatga gacaccgcag ataggagacg tagacgcttc gtttggcgtt gcaggaaata
    35461 ctgtctctat ttcagggcaa ggatttggta gtgctcaagg tcagcttcat tttggtgata
    35521 gcaaagcaga tattgtgtca tgggacgata ccttgattca atttaagata cctgctgtag
    35581 ctgctgggaa ccatgatatt aaggtgacca catctacagg acaaagcagt agcccttaca
    35641 aagcctttga agtgttaaca gataagcaaa ttccagtaag attggtggtc aataatttca
    35701 acactgtatt aggtgagcag ctttatatcg ttggtgatgt ggttgagctt ggggcaaatg
    35761 ataatcataa agctttaggg cctattttta atgcaacaca gtcaattgcg cagtacccaa
    35821 attggttcta tgatgtcaat ctgcctatta acaaaaccat taactgtcat cttgtaaaga
    35881 aggatagttc tggtaaagta ttgtggacta gtccagaaac ctataccatt aaaactgata
    35941 gcaaggctca aaccatttca ttgaaaaaat agttgcgtta tctgtgatgt tatttaatac
    36001 tctatgaagg aggagaacca taaaagggtg atagagagga atgacaaatg cttaagaatg
    36061 aaaaaatgaa gaatccacaa aaagccatgt ggctttcaat aatccctggt ctggggcaac
    36121 tctacaatac tcaaaaggta aaaggcttta ttttgcttct tgtgttttta ggtgagctgc
    36181 tagaggcttt ctttgttggt attccggctc ttgctggctt gtacagcctt ggtagtgtac
    36241 caatggagga tcattcccta ttcttattga ttaagggagc tatgcagctt atcctatttg
    36301 ccttgttttt gatctttcat ttggctgcta tgcgagatgc tagactagtg gcaagggaga
    36361 tcaatgcagg ccatagcatt tcattaacct taaaggagat ggtacaatcc atctatgaaa
    36421 agggctttcc ttatttgctg attattccag cctacttggc catggccttt gccattgttt
    36481 ttccggtgct tgttacttta ttaattgcat ttacaaacta tgattttagg catattcctc
    36541 cctataaatt attagattgg gttggcatta agaattttaa aagcatttta gagcttagca
    36601 cctttaagtc agcctttggc tctgtgctgt catggacctt gatttggacc ttggcggcaa
    36661 cgagtctcca gattgtgata ggaatagcga ctgctattat tgccaaccag tcctttgtga
    36721 agtgcaggcg catttttggg gtgattttct tgctgccttg gggggtgcct gcttttatct
    36781 cgatcatgag ctttggtaat ttctttaatg attctatcgg tgctatgaat gttcaggtct
    36841 taccattttt agaaaagttt gtgccatttg cagattttgg gattatccca tggaagacag
    36901 atcctttttg gacaaaggtt gcggtgatta tggttcaggg ctggctgggc tttccttata
    36961 tttatatttt ggtgtctggt attttacaat caattcctgc tgatttgtat gaggcagcaa
    37021 cggttgatgg tgcaacagcc ctgcagaagt ttcgccaaat taccttgcca atgatctttg
    37081 ctgtcgcagc cccgacctta atctcgcagt atacctttaa ttttaataac ttctccatta
    37141 tttatctctt taataatgga ggtcctggta cagttggcgg tggcgcaggg tcgacagata
    37201 ttttgatttc ttggatttac aagctgacca cacaaacgtc accacagttt tccattgctt
    37261 cagcggtgac cttaatcatt tccttgattg ttatttctgt atcattgata acctttaaaa
    37321 aattcaaagc ctttgacatg gaggatcgct aaatgggtag gaattatttg ccacagtcag
    37381 tgaagaagaa gcgcttgtta gctcagctgt tgacttacag ctatttgcta atcctgtcga
    37441 tcatcatctt atttccaatc ttggtgaccg ttagctcagc ctttaggcca ggaaatacaa
    37501 ctgcctttag ctttcatatt gatgggcctt ggaccttatc aaactttgag acactctttc
    37561 aggacaccta ttacttaaga tggtactgga acacgttagt tgtcgccttt ttcacgatgc
    37621 tgatccaggt gacagtcatt acgctgacag gctatgctta cagccgttat cacttttttg
    37681 ggcgtcaaaa gagtttggtc tttttcttag tggttcagat ggttccgaca atggctgcct
    37741 taacagctta ttttgtgatg gcttggttgt ttaatgctct gaatcactat tggttcctca
    37801 ttctgattta tgttggagga ggcattccga tgaatgcttg gttgatgaag gggtattttg
    37861 atactgtgcc ttatgattta gatgagtcag ctaagctaga tggctctggt cactttagga
    37921 ccttctacca aattgtattt cctctggttc gtcctatggt tgctgttcag gccctatggg
    37981 cctttatggg gccatttggt gactttatgc ttgctaagtt tctcttgcgt gaacaggagc
    38041 attacaccgt agcggtaggt cttcagtcat tcatcactaa cgacgctagg gatcctaagg
    38101 tcacattgtt tgcagccggg gccattttaa ttgcagtgcc aatttcagtg ctattcttct
    38161 ttttacagaa gcattttgtt tcaggcttaa ccaatggtgg aacaaagggt taatttatct
    38221 ttcaaggagc ctttatcatg actaatgatc gatttcctat ttcttacaca accattattt
    38281 tttctcctaa aatgatattt gctcgttgca gtgccttttt gtggtggcag aatgtgattt
    38341 tagtgatctt tctaaatgct ctggtgttaa tgccgatcac gctgcattat gcaagcttga
    38401 agagctatcc cttagagcac atagttagta atggtttaga ctccttgaca gaaaaaacct
    38461 atcatgcctt gacacaaggc actatttggc atgatcgcta tgatggaaaa acagtcctta
    38521 tagaggatac tgatgctgtt gttgctgtat tgccaacacc agaaatagta gaagagctaa
    38581 agaaagatca aagaagccag ctgatattaa cagaaacctc atggatttta agctttcctg
    38641 atggtcaaag gctaactgct aaggttaaag gcaacaagga aaggctaacg cgcttaacct
    38701 ctctagaggc tgtcaaggcc tttgttaatc agcaatggta caatagcaat cgtgccgctg
    38761 tgcttgcctt tttgctgcta gtggctagca gtgtggtcta tctaggagcc ggtttagtga
    38821 tcggaattgg ctcgttatca ctgttattaa caagatctgc tagattattt tcactcaaga
    38881 gctactcaga atgcttgggt ttgctagtga attgctttgg acttcctacg cttttagcag
    38941 tgcttataag tttttgggtg cacaatccta ttgttatcat gaatagtcag gtctttggca
    39001 cactgctcat gctggttcta gtcttttaca aaactcagtt tagagatgag gagcaagcac
    39061 tagcttagcc cttgctgaca tcaaaaaatc cctccc
//
LOCUS       DARYYD010000016        39087 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.016, whole genome shotgun sequence.
ACCESSION   DARYYD010000016 DARYYD010000000
VERSION     DARYYD010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39087
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.016"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(37..1368)
                     /locus_tag="TV188_000740"
     CDS             complement(37..1368)
                     /locus_tag="TV188_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HEL1534116.1"
                     /translation="MEFLGPIGVLLGIIAIVYFSLKEIHITIAAPMATILVVLLNSMP
                     LVESLLGKEPNNYMGALGGYIMSYFAIFLLGSILAKLMEVSGATVSIAEFILKKVGYQ
                     NPYRILVAIFIISAILTYGGISLFVVMFAVLPLARSLFKKMDLAWNLIQVPLWLGIAT
                     FTMTILPGTPAIQNVIPIQYLNTSLTAALVPSILGSVGCIAFGLFYMKRCLTKSLEVG
                     ENYATYTSQTNEDTTERVLPPFVVSILPLILLIVIAIIGSLLGDEFVKKNIIYVALLT
                     GIISAIVLFNKYIDKKIATLSIGASGAVGPIFATASAVAFGSVVTAASGFGVFSDIIL
                     NIPGPPVISLTVLTSAMAAITGSSSGALGIVMPNFAQYYLDAGVSPEIIHRVAAVASN
                     ILTIVPQSGVFLTFLSLTGLSHKNGFKQTFITVFGGTLVAESIIMLTSLFF"
     gene            complement(1459..2238)
                     /locus_tag="TV188_000741"
     CDS             complement(1459..2238)
                     /locus_tag="TV188_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HEL1534117.1"
                     /translation="MNMSKQVVFVTGAASGIGKQIGETFLKEGKIVVFSDINQEKLDA
                     VVDEYTTKGWAADSVLCDVTNEEAINKAIDYTVEKHGRLDILVNNAGLQHVAMIEDFP
                     TAKYEFMLKVMLTAPFIAIKRAFPTMKKQGFGRVINMASINGVIGFAGKAAYNSAKHG
                     LIGLTKVAALEAAELGITVNAICPGYVDTPLVRGQFEDLSKTRKIPLENVLEEVLYPL
                     VPQKRLIDVQEIADYVSFLASDKAKGITGQPVILDGGYTAQ"
     gene            complement(2269..2913)
                     /locus_tag="TV188_000742"
     CDS             complement(2269..2913)
                     /locus_tag="TV188_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HEL1534118.1"
                     /translation="MVKELSKEEIQERIAKRVALELPNNSLVNLGIGLPTKVARFLPE
                     GVTIMLQSENGFVGLDKVGDDIDPTIVNAGGQPVGIVPGGAFFDSTTSFGIIRGGHVD
                     ATVLGALQIDEKGNIANYLIPGKMVPGMGGAMDLLVGAKKVIVAMEHTNKGKWKILKE
                     CSLPLTAAGVVDKIVTEMGVFTVTPEGIAVEEIHPDYTFEEVQEATEARLIYHN"
     gene            complement(2919..3569)
                     /locus_tag="TV188_000743"
     CDS             complement(2919..3569)
                     /locus_tag="TV188_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HEL1534119.1"
                     /translation="MNKRISIEEAVNLVKDGDTIMVGGFMTNGSPERLIDALVAKGVT
                     NLTLICNDAGFPDKGVGKMVAQHRFRKIIASHIGLNKEAGRQMTAGETVIDLVPQGTL
                     AERIRAGAYGLGGFLTPTGIGTLVEEGKQKLQVNDKDYLLELPLKADVALIFADKADE
                     LGNLCYKGSENNFNQVMAANAKVTIVEAREIVSLGDIEPIAVQTPGIFVNYLVEGE"
     gene            complement(3584..4774)
                     /locus_tag="TV188_000744"
     CDS             complement(3584..4774)
                     /locus_tag="TV188_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HEL1534120.1"
                     /translation="MLVKEVVITTAVRTPIGSFGGAFKSVSAVQLGKVVVEALLEKSG
                     VKPEQIDEVIFGNVLHAGLGQNVARQVGITAGIPNDKPAFTVDMVCGSGLKSIELAAQ
                     SIVCGDSDIIIAGGTENMSQASYVLKDYRWGGRLGDGKIIDTMVNDGLTDAFHDYHMG
                     ITAENIAKNYGISRKAQDIFALASQEKAAAAQAAGRFVDEIIPVPVPQRKGDPILVAE
                     DEYIKAGTTLEKLTALCPAFVRDGSGTVTAGNASGINDGAAAVLLMSRDKAEELGLPI
                     LGAIKGYASAGVAPEVMGTGPIPSTQKALAKVGWTIEDLDLVEANEAFASQAISVVDE
                     LGLNAAIVNVNGGAIALGHPIGASGARILVTLLHEMEKRQAHKGLATLCIGGGQGTSV
                     LIEK"
     gene            4966..5868
                     /locus_tag="TV188_000745"
     CDS             4966..5868
                     /locus_tag="TV188_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1534121.1"
                     /translation="MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQ
                     GIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPL
                     ILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
                     SFQIQESELCAFVSKNHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDIN
                     PQIILESASWDFLINSTRINPQLMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRL
                     KKDHYSTIEEYIFNKMLEKFHVIE"
     gene            complement(6765..7907)
                     /locus_tag="TV188_000746"
     CDS             complement(6765..7907)
                     /locus_tag="TV188_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534122.1"
                     /translation="MKALLPFELKKLIRTKSVLGMFIVSLLAIFGLFYINFFNGQISG
                     SSIDKIHGRDAVEINKRFAEEHTGQLSNELLIRTIKDYTLGGSSKNPVFNVYGYYVTS
                     HFDPKFRDYYFNLKKEETIDFSKITPKSQTALGSYLPFKELKLGNFAPWNQLFLVINS
                     AYILLLLLSVYFIAPVFSGDTAKNMNPILLTTRYGRNKLTIAKIISSYLISTSVFVTF
                     YAIILAVFVWYFGLSGWDTSVQLNLYWINSNVNIMAFPEKMTLLGTFINLVTYQFIGL
                     ILITAITILISSKVKSPLTGFALSAASVFVPSFLMDIFQAGIPHKVLSILSVSTASTP
                     NIMLKLAYDGFFGSFWVDGLVIVMIRLAFAFLCLYLAYLSIKRVSQ"
     gene            complement(7904..8767)
                     /locus_tag="TV188_000747"
     CDS             complement(7904..8767)
                     /locus_tag="TV188_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534123.1"
                     /translation="MLLELNQLSKSYGSKNILRRITTQFTPGLYGLLGANGTGKTTLL
                     NLISHFTTPDEGEILLDHKPQSEEFYQHIGFLPQQFSYYGRFSGRDFLLYMAALKGIP
                     KHKAKQETDELLKLVDLYDVRLKRIASYSGGMKQRLGIAQALLNDPKILILDEPTVGL
                     DPKERVKFRNIISELSANKIIILSTHIVSDVEAIAKEIIILKNGQFIHKSSSQELLKT
                     IFGKVWEFSVSDGSPLPRHGQYAVVNEKLVSSSRVFRVVSDEKPNQLAQLVSPTLEDL
                     YIYHFREEQVL"
     gene            complement(8778..9104)
                     /locus_tag="TV188_000748"
     CDS             complement(8778..9104)
                     /locus_tag="TV188_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HEL1534124.1"
                     /translation="MKYVILYKNRSVVKLPISETYDVTTHSSKPHTVVFVTLKGEFGA
                     ATSLRQIEGESAGKLKRCHRQYFINESKISGFDYATRIIKVTDSRISYRRSLLSTELQ
                     VLSRLI"
     gene            complement(9708..9872)
                     /locus_tag="TV188_000749"
     CDS             complement(9708..9872)
                     /locus_tag="TV188_000749"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534125.1"
                     /translation="MDSMTVDAEKASQLDLGIENAGWFHFKLTTAIKLKQVEKVFLFT
                     AIFNRVDEFI"
     gene            complement(10111..11007)
                     /gene="era"
                     /locus_tag="TV188_000750"
     CDS             complement(10111..11007)
                     /gene="era"
                     /locus_tag="TV188_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEL1534126.1"
                     /translation="MFKSGFVAILGRPNVGKSTFLNHVMGQKIAVMSDKAQTTRNKIM
                     GIYTTETEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVETVLFMVPADEKRGKGDD
                     MIIERLKAARIPVILVINKIDKVHPDQLLEQIDDFRSQMDFKEIVPISALQGNNVETL
                     VQLLKDNLEEGFQYFPEDQITDHPERFLVSEMVREKVLHLTQQEVPHSVAVVVDSMKR
                     DEVTDKVHIRVTIMVERDSQKGIIIGKQGAMLKKIGKLARRDIELMLGDKVYLETWVK
                     VKKNWRDKKLDLADFGYNQKEY"
     gene            complement(11143..11544)
                     /locus_tag="TV188_000751"
     CDS             complement(11143..11544)
                     /locus_tag="TV188_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEL1534127.1"
                     /translation="MASQDNNKRKWKNRTVIASLEFALTGVLTAFKEERNLRSHLLSA
                     LLASLAGIVFGISAIEWLFLLLAIFLVITLEIVNSAIENVVDLASDYHFSMLAKHAKD
                     MAAGAVLVISGYAVLTGLIIFVPKIWRMLCH"
     gene            complement(11525..12022)
                     /gene="ybeY"
                     /locus_tag="TV188_000752"
     CDS             complement(11525..12022)
                     /gene="ybeY"
                     /locus_tag="TV188_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018167004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEL1534128.1"
                     /translation="MYIEMIDETKQVSQEMMEQTIDLLNFAAKTIGKEDKEMAVTFVT
                     NDRSHALNLEYRDTDRPTDVISLEYKPELPIAFSQEDLELDPDLAGMIQEFDAYIGEL
                     FISVDKAHEQAEAYGHSFEREMGFLAVHGFLHINGYDHYTPEEEKEMFTLQEEILTAY
                     GLTRQ"
     gene            complement(12371..12997)
                     /locus_tag="TV188_000753"
     CDS             complement(12371..12997)
                     /locus_tag="TV188_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1534129.1"
                     /translation="MASFFEKLAEHRYLETERLCLRPVTLDDAKAMFDYASDEETVRY
                     SFPANQTIEETRQVIASVYLASPLGRWGIVLKETGDFIGTLDLHHIQLDLGRAEIGYC
                     LHKHHWGRGYATEAVKAVLVLCFEALGMNCVIAKHDKANPALGRVMAKSGMCFSHEEP
                     YAKRDHLDSNRFVTVLHYYLTKEDYDKQKSLASANKPDRYLHNSFESS"
     gene            complement(13052..13627)
                     /locus_tag="TV188_000754"
     CDS             complement(13052..13627)
                     /locus_tag="TV188_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEL1534130.1"
                     /translation="MTELLQAIMADPANRDYTKKGIEPLYAAPQTARIVIVGQAPGIV
                     AQETRLYWNDRSGVRLRAWLGVDDRTFYQSGLFGVLPMDFYYPGKGKSGDLPPRKGFA
                     AKWHGPLMALMPQVELVVLVGQYAQQYYLGEGCRRNLTETVQHFEDYLPDYFPLVHPS
                     PRNQLWLAKNAWFEEELVPVLKDKVRQILRG"
     gene            complement(13674..14774)
                     /locus_tag="TV188_000755"
     CDS             complement(13674..14774)
                     /locus_tag="TV188_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEL1534131.1"
                     /translation="MHYSTDISLNHPDDLLALFGSNERHLKMIESHLNVVIHARTERV
                     QIIGDDERAVELARLTIQALLVLVGRGMVINTSDVVTALSMADSDRLDQFVALYEEEI
                     IKDFYSKPIRVKTLGQKAYVDSIKHHDVVFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKEQTTRLMERDIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFQSKMIVNGDISQIDLPRHITSG
                     LIDAAQKLQAIKQIDFVHFSAKDVVRHPVVAEIIKAYETVGSKAESLKSSPNQLQHQT
                     KAPDRPKTETGQSTSGLTTYEVIGELPKEDKS"
     gene            complement(14877..15092)
                     /locus_tag="TV188_000756"
     CDS             complement(14877..15092)
                     /locus_tag="TV188_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEL1534132.1"
                     /translation="MRKAFYTWLMAQRNSTSNKPAALLADLVFEDPTFPKHTDDFETI
                     SRYLEEEASFSFNLGQFDQIWEDYLSH"
     gene            complement(15089..15598)
                     /gene="msrA"
                     /locus_tag="TV188_000757"
     CDS             complement(15089..15598)
                     /gene="msrA"
                     /locus_tag="TV188_000757"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HEL1534133.1"
                     /translation="MERAIFAGGCFWCMVQPFEEQAGILSVRSGYTGGHVHNPSYEQV
                     CSKTTGHTEAVEIIFDPSLISYSDLVELYWAQTDPTDAFGQFEDRGDNYRPVIYYTDE
                     RQREIAERSKQTLQASGRFDQPIVTSIEPAEPFYLAEDYHQGFYQKNPERYAQSSAIR
                     HQFLEEHWQ"
     gene            complement(15936..16793)
                     /gene="cvfB"
                     /locus_tag="TV188_000758"
     CDS             complement(15936..16793)
                     /gene="cvfB"
                     /locus_tag="TV188_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEL1534134.1"
                     /translation="MNHLLATVITGLVKEENSQFYLVQKEGLSFALAKEEGSHRLGDM
                     VKGFVYTDMKQRLRLTTKPIDARRDHYGWGEVTTVRRDLGVFVDTGIPDKEIVVSLDV
                     LPELKDLWPKKGDRLYLKLVVDKKDRIWGLPAEPEIFQRLASPAYDNMQNQSLPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYTEPRLGQVLTARVIGFRERDRTLNLSLKPRSF
                     EMLENDAQMILTYLKSNGGYMTLNDKSSPEDIKATFGISKGQFKKALGGLMKANKIKQ
                     DVTGTELIS"
     gene            complement(16927..17484)
                     /gene="frr"
                     /locus_tag="TV188_000759"
     CDS             complement(16927..17484)
                     /gene="frr"
                     /locus_tag="TV188_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEL1534135.1"
                     /translation="MANAIIETAKERFTQSHHSLAREYASIRAGRANASLLDRIQVDY
                     YGAPTPLNQLASITVPEARVLLISPFDKSSIKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRKELAKEVKKVGETAKVSIRNIRRDAMDEAKKQEKAKEITEDELKALEKDI
                     QKATDEAVKEIDRMTADKEKELLSV"
     gene            complement(17521..18249)
                     /locus_tag="TV188_000760"
     CDS             complement(17521..18249)
                     /locus_tag="TV188_000760"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEL1534136.1"
                     /translation="MKPKYQRILIKLSGEALAGDKGVGIDITTVQSIAKEIAEVHNSG
                     VEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQHYGVDTRVQT
                     AIPMQNVAEPYIRGRALRHLEKGRIVVFGAGIGSPYFSTDTTAALRAAEIEADAILMA
                     KNGVDGVYNADPRKDANAVKFDELTHGEVIKRGLKIMDATASTLSMDNDIDLVVFNMN
                     EAGNIKRVVFGEHIGTTVSNKACD"
     gene            complement(18548..19228)
                     /locus_tag="TV188_000761"
     CDS             complement(18548..19228)
                     /locus_tag="TV188_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534137.1"
                     /translation="MIEFRHVYKSFHQKPVLTDCHFQMEKGESLGIMGESGSGKTTLA
                     RLIIGLEQPTAGQVLFHGQPYSVKVCGPRILLVFQDALRSVNPLFTIQEILTEALSKD
                     FALEEVVQILAAVGLDATHLGKKARELSGGQLQRVCIARALLLRPEVIIFDEALSGLD
                     PITQGQLLDLLYELKQEYQLTYIFIAHDANICQAICHRVLLLEQGRLVAVRDKEPQTS
                     CGGIGLDN"
     gene            complement(19215..20003)
                     /locus_tag="TV188_000762"
     CDS             complement(19215..20003)
                     /locus_tag="TV188_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534138.1"
                     /translation="MERLIVNDLSAYNGSDVLLSKLNLELPLGSSLVIVGRSGSGKTL
                     LTKLLIGQCPSNVQMTGRITCQDMRLDQLDAKQWQSIRGRHMAYMVQNPMAMFNPFQT
                     IEAHLLETIRSHERLSKRACLKRALPFMRELYLEQPEELLRKYPFELSGGMLQRVMLA
                     ILLCLDPQIIILDEPTSALDDANRSNIIRMLKLLQDKGKTIITVTHDYQLAQTLGGQL
                     LVMSKGKIIEQGSVESIFHRPSQAATKELLLQNHYDRLIRYDRV"
     gene            complement(19991..20797)
                     /locus_tag="TV188_000763"
     CDS             complement(19991..20797)
                     /locus_tag="TV188_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1534139.1"
                     /translation="MPKYVIGSAVMLLLLFICVLFAPYLAPFDPHAVDVASKLMPPSQ
                     QHLLGTDQLGRDVLSRLLYGAKYSLLLAVTISLLELSIGAVVGLVVGWYQGRLEAAFL
                     WLADVVSAFPSFLLSLATMGILGQGIGNMILAIVLVEWLYYARLMVTMVKSAKAEPYV
                     ISAQTMGLSVRHILKKHILPFVYRPIVVLALMNIGNIILMISSFSFLGIGVQPNVTEW
                     GMMLHDARSYFRTALWLMMSPGLAILVTVLAFNSLGDYADAKGWRKTWNG"
     gene            complement(20782..21723)
                     /locus_tag="TV188_000764"
     CDS             complement(20782..21723)
                     /locus_tag="TV188_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1534140.1"
                     /translation="MMKKLISTFGALLMISIVTFVLVKLSSANPAEQYLRLSKISITP
                     EALHNARLYLGLDKPLWEQYVTWLSDILVGNFGTSYVLKVPVLPLVVERFLATLMLSL
                     TSFLLVLVIAFPLGVGSGLFEHSLFDRLVRLFSFVAVSMPSFWLGYLLIIAFSVKLNL
                     LPVSGKAGASSLILPSITLSFSLIGQYTALIRKAISEQLTSLHVENARLRGVKTYYIV
                     KHHLIRNAFPAIATGLSLTFVYLMTGSIIVEDIFSWNGIGSLFVMSLKAADIPVIQAC
                     MLLFGALFLLHHVITQELVSFIDPRLRKTKEEACPNT"
     gene            complement(21801..23423)
                     /gene="nikA"
                     /locus_tag="TV188_000765"
     CDS             complement(21801..23423)
                     /gene="nikA"
                     /locus_tag="TV188_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HEL1534141.1"
                     /translation="MKTKLNVLLLFFFALLLTACQNAKQASYRTDQLRIAWGEDFGDV
                     NPHRYNPDQFVIQDMVYEGLVRYGDKGNIEPALAESWTISPDGKTYTFNLRQAKFSDG
                     SDFNAQNVKRNFDSIFSEQNKGNHNWFHFTNQLDSYKALDDHTFEIKLKEAYSATLYD
                     LSMIRPIRFLADAGFPDGDDTNKHNVKKPIGTGQWVVKEKKANEYITFTRHESYWGEK
                     PKLKEVTIKIMPDAETRALAFEAGDIDLIYGNGLISLDTFVQYAKDKKYVTDVSQPMS
                     TRLLLLNAKQSVFQDKRVRQAMNHAVDKKAIAKHTFRGTETAADTIFSKTTPHADAGL
                     VPYEYNLQKAKDMLTAAGWKENQEGIREKDGQQLRLQVPYISTKATDKDLVEYFQGEW
                     KKLGIDVVLTAMEEDDYWANAKTGQFDMMLTYSWGAPWDPHAWMTALTAKADHGHPEN
                     IALESLPSKAEIDRLIKSVLIEPDGDKVDKGYKQVLSLLHDEAVYIPLTYQSVVSVYR
                     KGDFKTMRFAPEENALPLRYIEKSAADKAVKN"
     gene            23925..25565
                     /locus_tag="TV188_000766"
     CDS             23925..25565
                     /locus_tag="TV188_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1534142.1"
                     /translation="MKKTMKKMLAASTLCIIMSGSFISGSARVLAEEYYGWNDVTGSK
                     SPFPLYVTPKNGDKNIKVQQTVVYCFNRDGQWPENWEKRIYESPDKVPHKLPEYNKKS
                     GSDNLFQLLNPKIKIKNPMAALLAVLEDGYPTSSSSGVNQRTTQLAIWHFTDGLSNLA
                     QFHLTPEETSAYNKLIEKGTNASNQSENKLLNKTLDIYSYIDGTGDKKHNYQHLLGST
                     PIPIDNSKENKCQCTKVDLMRTGDGVKIIVYVDNNGNNRYDNGDKMLKEETIKHGQRG
                     PAGESGKPGPKGDRGETGARGPAGPQGKPGKQGPRGDKGETGERGPQGEKGEPGTPGP
                     KGEDGKDGAPGRDGQPGPKGEKGDPGKDGQDGKPGEKGEPGIPGPKGEDGKDGAPGRD
                     GQPGPKGEKGDPGKDGQDGKPGKKGDPGRDGKDGEKGERGEQGPKGERGEQGPQGERG
                     EQGPRGENHTPTPDPMPEPAPKPESKPEPKPTPQPEVKPLPETKPQKPTKPSAMASQP
                     SSKALPKTNDTSGLMTVLGTGLLSLLGLGFLAKRKRKQ"
     gene            complement(25809..26498)
                     /gene="rplA"
                     /locus_tag="TV188_000767"
     CDS             complement(25809..26498)
                     /gene="rplA"
                     /locus_tag="TV188_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004232886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEL1534143.1"
                     /translation="MAKKSKQMRAALEKVDSTKAYSVEEAVALAKETNFAKFDASVEV
                     AYNLNIDVRKADQQIRGAMVLPNGTGKTQRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINGGWLDFDVVIATPDMMAIVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADKAGNVQAIIGKVSFDADKLVENFKAFHEVMVKAKPATAKGTYMTNVSITTTQ
                     GVGIKVDPSSF"
     gene            complement(26604..27029)
                     /gene="rplK"
                     /locus_tag="TV188_000768"
     CDS             complement(26604..27029)
                     /gene="rplK"
                     /locus_tag="TV188_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEL1534144.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFDFITKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANIEAAMRMIEGTARSMGFTVTD"
     gene            27265..28062
                     /locus_tag="TV188_000769"
     CDS             27265..28062
                     /locus_tag="TV188_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1534145.1"
                     /translation="MHKKVTIKDVAREAGVSVATVSYVINNREDQKISPETRNKVLQM
                     INLLNYRPNQAAKSLVTQKRQLIALYYKEHSSVLKRAEQLHFITQLSAFLYTKHYHLI
                     CLNQEYIGKYDVADVILTLEVTKEEFYKIGNSNFVPLIAIDSIIDDPLFFQINSDPHL
                     LFNKASAYFAGEPFELVSLPIQNQEITQGLAQQFDNICWIHSICDIESVSKGNILVID
                     DTVNHILSKHKNKLYLPSISEAKLLKLFQAIEWASKREAINNHNILV"
     gene            28217..28567
                     /locus_tag="TV188_000770"
     CDS             28217..28567
                     /locus_tag="TV188_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEL1534146.1"
                     /translation="MIIYKLTALAFIILTPLFSMIMISLLRLGRRGLKFPDLALPLFV
                     FEIVIVSGKFFTHHLLPYYLIVMSLLAIVMALLLIIRIQQFSYRRFFKLFWRVGFLVT
                     LLFYLMLVGLIFIV"
     gene            complement(28896..29351)
                     /locus_tag="TV188_000771"
     CDS             complement(28896..29351)
                     /locus_tag="TV188_000771"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534147.1"
                     /translation="MTISDQKVNASQYRWRQYYYRMSPTERELKKEKEVLRNFIATIK
                     LSYSEANEMEAKVYGADSFSKLRAIKEELQSLKSRYFKISNKVEIVSSLIDEHFPEGH
                     SRNIMKKYRLEFLDRLMGIQYDVGLNKDRALDDLSERIIMTRKKLWYIQ"
     gene            complement(29726..32125)
                     /locus_tag="TV188_000772"
     CDS             complement(29726..32125)
                     /locus_tag="TV188_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEL1534148.1"
                     /translation="MARRTQRQKNPPKRRLTKAELEKQKAIKRMIASFSCALLLVFAM
                     LRLGALGVTLYNLIRFMVGDLANLLMLAVLFYLFFFKWLRQKDGLIAGFIILFLGLLV
                     EWHAYLFSLPQLAHQAIVAGTIQLITNDLLAFKVSEFVGGGMLGAMLYKPISFLFSNI
                     GSYFIGFLFILLGLFLMTPWDIYDVSHFVKTLFEKLSLAYQENKEKRFVEREKQRLLA
                     EEERLAREALEEQEYLANQAINPETGELLAEPEDLLMEMADQKESEAFFEPEILAYDS
                     HPADDEPEAFGDEEESVPEAPLTGASAIAGEAPLSDDEELSVEVDFTPKTNLLYKLPT
                     IELFAADKPKNQFKEKYLVRQNIKVLEDTFRSFGIDVKVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLADDLALALAAKDVRIEAPIPGKSLVGIEVPNSEVATVSFRELWEQSNTS
                     DDKLLEIPLGKAVNGSARSFDLTRMPHLLVAGSTGSGKSVAVNGIISSILMKARPDQV
                     KFLMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFSKVGVRNI
                     AGYNAKVEAYNKQSEQKQIPLPMIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRIAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVSFIKEQAEADYDDYFDPGEVSDSDYGSSGAPEGDP
                     LFEEAKALVLETQKASASMLQRRLSVGFNRATRLMDELEEAGVIGPAEGTKPRKVLQT
                     N"
     gene            32245..32418
                     /locus_tag="TV188_000773"
     CDS             32245..32418
                     /locus_tag="TV188_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534149.1"
                     /translation="MEKEFNTLTYGKLPLQIDMGHGKLIPKGVEVKAIVDMQTGQVTF
                     KVSQEDLEKLRNS"
     gene            32505..33311
                     /locus_tag="TV188_000774"
     CDS             32505..33311
                     /locus_tag="TV188_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003054349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEL1534150.1"
                     /translation="MKKLLSFGLIGLALLSLSGCESIDRAIKGDEYVDEKIAREESET
                     AAKAYEAKIKKALKADADQFPQLNKEVDKDEAKVIIKTNQGDITLKLFPKYAPLAVEN
                     FLTHAKEGYYDKLLFHRVINNFMIQTGDPKGDGSGGESIWKGKDSKKDAGQGFANEIS
                     PFLYNIRGALAMANAGADTNGSQFFINQSKLNQAKALSIDNYSKPIIDSYEEGGNPSL
                     DGGYTVFGQVIEGMDIVDKIAASPVGPNDKPIENITINAIDIVKDYSFKK"
     gene            complement(33467..34300)
                     /locus_tag="TV188_000775"
     CDS             complement(33467..34300)
                     /locus_tag="TV188_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1534151.1"
                     /translation="MYLKFFEGLMSYHFLQNALITAVVIGIVSGAVGCFIILRSMSLM
                     GDAISHAVLPGVALSFILGINFFVGAIVFGLLASVIITYIKENSVIKGDTAIGITFSS
                     FLALGVILIGIANSSTDLFHILFGNILAVQDSDKWITIIVSVFVLAIIVLFFKELLIT
                     SFDPVLARSMGMKVTAYHYLLMILLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKVMLVISSCLGAMTSVLGLYLGYTFNIAAGSSIVLTSAVVFLISFFVSPKQGYFKKH
                     S"
     gene            complement(34301..35026)
                     /locus_tag="TV188_000776"
     CDS             complement(34301..35026)
                     /locus_tag="TV188_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1534152.1"
                     /translation="MIDTQNLSVSYNGNVKALDNISLQIKGPAIVGIIGPNGAGKSTL
                     MKAMLNLLDYSGQVTVDQKDGRRLGHTIAYVEQRSMIDYNFPITVKECVSLGTYTRLG
                     LFRRVGKKEYDQVDQLLEQVGLAGFGNRPIKSLSGGQFQRMLVARCLIQESDYIFLDE
                     PFVGIDSVSEKIIIDLLKDLKKAGKTILIVHHDLSKVEHYFDELVVLNKELIAYGSVD
                     EVFTVETLSKAYGDHLFLGKGMF"
     gene            complement(35086..36018)
                     /locus_tag="TV188_000777"
     CDS             complement(35086..36018)
                     /locus_tag="TV188_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HEL1534153.1"
                     /translation="MKKKLSLALSAFLAVFMLVACSNGGNKEAKSDKLKVVVTNSIIA
                     DMTKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVEKTSNADLILYNGINLEDGGQAWFT
                     KLVKNAKKEKDKDYFAVSDGIDVIYLEGESEKGKEDPHAWLNLENGVIYSKNIAKQLI
                     AKDPKNKETYENNLKAYVEKLEKLDKEAKSKFDAIADNKKLIVTSEGCFKYFSKAYGV
                     PSAYIWEINTEEEGTPDQISSLIEKLKDVKPSALFVESSVDRRPMETVSKDSGIPIYA
                     EIFTDSVAKKGQDGDSYYAMMKWNLDKISEGLAK"
     gene            36164..36811
                     /locus_tag="TV188_000778"
     CDS             36164..36811
                     /locus_tag="TV188_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEL1534154.1"
                     /translation="MTPNKEDYLKCIYEIGEQNIKISNKMVAERMKVSAPAVSEMIKK
                     MIAQGWIVKDKTCGYYLTEQGQRLVANLYRKHRLMEVFLIHQLGYTAREVHQEAEVLE
                     HTVSDMFIDRLDKTLGYPTFCPHGGTIPRRQQPLIEINKTTLNTIKELGIFRLSRVHD
                     HFELIQYLEAHQLTINSEFRLIQIDDFAKTYTITYADKELIIPENIAKQLFVTAI"
     gene            complement(36867..37568)
                     /locus_tag="TV188_000779"
     CDS             complement(36867..37568)
                     /locus_tag="TV188_000779"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEL1534155.1"
                     /translation="MKIGIIAAMEEELRFLLEQLHDSQEHQVLSNTYYTGRLGRHELV
                     LVQSGVGKVMSAMTVAMLAEHFQADAIINTGSAGAIASGLAIGDVVVADRLVYHDVDV
                     TAFGYDYGQMAAQPLYFDSDSKLVETFKQVLDQEKTNSRIGLIATGDSFIAGQDSIDT
                     IKAHFPETLAVEMEGAAVAQAAQAAGKPFIVVRAMSDTAAHDANMTFDQFIVEAGKKS
                     AKVLIAFLEALPDKK"
     gene            complement(37592..37840)
                     /locus_tag="TV188_000780"
     CDS             complement(37592..37840)
                     /locus_tag="TV188_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534156.1"
                     /translation="MGKPLLTDDIIEKAQRGEQFEPDDYADFETKIMTFEDKHTDRIY
                     KSRRIENAKRSRFQSRLNLILLAVLVLIALLVYAVFNL"
     gene            complement(37840..38394)
                     /locus_tag="TV188_000781"
     CDS             complement(37840..38394)
                     /locus_tag="TV188_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1534157.1"
                     /translation="MDFEEKTIKRQEIFDGHIFKVAVDDVQLPNGLGQAKRELIFHRG
                     AVAILAVTPERKLLIVKQYRKAIEAISYEIPAGKLEVGEANSALEAAARELEEETAYS
                     GDLRLIHEFYTAIGFCNEKIKLYLATDLQRVANPRPQDADEVIELLELSYQECMDLVA
                     QGKLVDAKTIIALQYYALHFGGDV"
     gene            complement(38425..>39087)
                     /gene="glmU"
                     /locus_tag="TV188_000782"
     CDS             complement(38425..>39087)
                     /gene="glmU"
                     /locus_tag="TV188_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="forms a homotrimer; catalyzes the acetylation of
                     glucosamine-1-phosphate and uridylation of
                     N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc;
                     function in cell wall synthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEL1534158.1"
                     /translation="ERINRQHMLNGVTLQNPAATYIESSVEIAPDVLIEANVTLKGQT
                     RIGSRSVISNGSYILDSRLGEGVVVSQSVIEDSVLADGVTVGPYAHIRPDSQLDESVH
                     IGNFVEVKGSHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKYQTVIGDHA
                     FIGSHSTLIAPVEVGENALTAAGSTIAQSVPADSVAIGRSRQVVKEGYAKRLPHHPNQ
                     AK"
BASE COUNT        11973 a         9065 c         7065 g        10984 t
ORIGIN      
        1 taatagacca atggttttcc attgatctac tgtgtattaa aaaaacaggc tagttaacat
       61 aataatgctc tcggccacca acgtaccacc aaaaactgta ataaaggttt gtttaaagcc
      121 atttttatgg ctgagaccag taaggctcaa gaaggttaaa aagacgccag actggggtac
      181 aatggtcaaa atattagagg caacagctgc cacacgatga atgatctcag gtgaaacgcc
      241 tgcatctaaa taatattgag caaaatttgg cattacgatc cctaacgctc ctgaagacga
      301 acctgtaata gctgccatag ccgaagtcag gacagtcaag ctgatcacag gtggcccagg
      361 aatattcaaa atgatgtctg agaatacgcc aaaaccagat gctgctgtaa caacagaacc
      421 aaaggctact gcagaggctg tcgcaaagat tggaccaacc gcaccgctag caccaatgct
      481 gagggtcgca attttcttat caatgtactt gttaaataaa acgatagctg aaataattcc
      541 tgtcaagagg gccacataaa tgatattttt cttaacgaat tcgtccccta gcagactacc
      601 tatgatggca ataacaatca agagtatcaa aggcaagatg ctgactacaa atggtggtaa
      661 aaccctttca gttgtatctt catttgtttg actagtatag gtcgcatagt tttcgccaac
      721 ttctaaactc ttagtcaaac aacgcttcat atagaaaaga ccaaaggcga tacagccaac
      781 actccctaaa atacttggca ccaaggctgc ggttagagac gtgttaagat attgtatagg
      841 gataacgttt tgaatcgctg gtgtaccagg taagatcgtc atagtaaagg ttgcaatccc
      901 caaccaaagt ggtacttgaa ttaagttcca tgctaagtcc atctttttaa agagagagcg
      961 tgccaagggt agaacagcaa acatgaccac aaagagacta ataccaccat aagtcaaaat
     1021 agcactgatg ataaaaatag ccaccaagat acggtaaggg ttttgataac ctactttttt
     1081 caagataaat tcagcaatgg aaactgttgc accactgact tccatcaatt tagctaaaat
     1141 agaccccaac aagaagatag caaagtagct catgatatag ccacccagcg cacccatata
     1201 gttatttggt tccttaccca agagtgactc aactagtggc atactattta gaaggacgac
     1261 caaaatcgtt gccataggag ccgcaatggt aatatgaatt tcctttagag aaaaataaac
     1321 gatggcaata atgcccagca agaccccaat tggtcctaaa aattccatag tgtttctcct
     1381 ctcacattca gaaggagcaa gagatagaga aatgtcactc tatctccaat cctcttattt
     1441 acactgaacg gacagctctt actgagcagt gtagccacca tccaagataa ccggttgtcc
     1501 agtaattccc tttgccttat cacttgctag gaaggagaca taatctgcaa tttcttgtac
     1561 gtcaatcaaa cgtttttgcg gtaccaacgg gtacaacact tcttccaata cattttcaag
     1621 cggaatctta cgtgtcttag agaggtcttc aaattggcca cgaacgagtg gtgtgtccac
     1681 atagcctgga cagatagcgt tgactgtgat acctaattct gcggcttcaa gcgctgcaac
     1741 ctttgtcaag ccaatcaaac cgtgttttgc tgaattgtaa gccgcttttc cggcaaaacc
     1801 aatgacacca ttgatagaag ccatattaat gacacgacca aagccttgct ttttcatagt
     1861 tggaaaagcg cgcttaatag cgataaatgg cgctgtcaac atgaccttca acataaattc
     1921 atattttgct gttggaaaat cttcaatcat ggcaacatgc tgcaaacctg cgttgttgac
     1981 caaaatatcc aaacgaccat gcttttcaac tgtataatca atcgctttat tgatcgcttc
     2041 ttcatttgtc acatcacaca aaacagaatc agccgcccag ccttttgtgg tatactcatc
     2101 aacaacagca tctaattttt cttgattgat atctgaaaag acaacgattt tgccctcttt
     2161 taagaatgtt tcaccaattt gtttaccaat accgcttgct gcacctgtta cgaatactac
     2221 ttgtttagac atatttattt cctcactttt tttaaatatt gttttctatc agttatgata
     2281 aattaatctt gcttcggtgg cttcttgaac ttcttcaaag gtataatctg gatgaatttc
     2341 ttctactgcg attccctctg gagtgactgt gaagacaccc atttctgtga caatcttgtc
     2401 aacaactcct gctgctgtca atggcaatga acactccttc aagattttcc atttgccttt
     2461 attggtatgc tccatagcaa caatgacttt tttagcaccg actagtaaat ccatggcacc
     2521 gcccattcct ggaaccattt tccctggaat aagatagttt gcgatgtttc ctttttcatc
     2581 aatttgcaaa gcgccaagaa ctgttgcatc gacgtggcca ccacgaatga tcccaaatga
     2641 agtggtgcta tcaaaaaatg ctccgcctgg tacgatgcca accggctgac cacctgcatt
     2701 aactatagtt ggatcaatgt catcgcctac tttatctaag ccgacaaaac cattctcaga
     2761 ctgcagcatg atagtcacac cttctggtaa aaatctagct accttggttg gcaagccaat
     2821 ccccaaattg accagggaat tatttggaag ctcgagtgcc acacgtttag caattcgttc
     2881 ttgaatttct tctttgctta attctttcac cataacgctc attctccttc cactagataa
     2941 ttgacaaata tgcctggtgt ttgaactgca atgggttcaa tgtctccaag cgagacaatt
     3001 tcacgcgctt caacgatggt cacttttgca tttgctgcca taacctggtt gaaattattt
     3061 tcagagccct tgtagcatag gtttcctaat tcatcagcct tatctgcaaa aattaaagcg
     3121 acgtcagctt tcaatggtaa ttctaacaga taatccttgt cattgacctg taatttttgc
     3181 ttaccttcct ctaccaaggt accgatgcct gtcggagtca agaagccacc cagtccgtaa
     3241 gctcctgctc ggattctttc agccaaggtt ccttgtggca ctaagtcaat cactgtttca
     3301 ccggctgtca tttggcggcc tgcttctttg ttcaagccaa tatgagaagc gataattttc
     3361 cgaaaccgat gttgtgctac cattttaccg acacccttgt ctgggaagcc tgcatcgtta
     3421 caaataagag ttaaatttgt aactcctttt gctaccaaag cgtcaatcag gcgctctgga
     3481 ctcccgttag tcataaaacc accaaccatg atggtgtcgc catcctttac aaggttaaca
     3541 gcttcttcta tgctaattcg tttattcatg aaaccatctc cttttatttt tcaatcaata
     3601 cagacgtccc ttgaccgcca ccgatacaga gtgttgccaa tcctttatgt gcctgacgct
     3661 tttccatctc gtgcaatagt gtgaccaaga tacgcgcacc gctagcaccg atcggatgac
     3721 caagagcaat agcaccacca ttgacattga cgatagccgc attaagacca agctcatcta
     3781 caacactgat agcttgtgag gcaaaggctt cattggcctc caccaaatcc aagtcttcaa
     3841 ttgtccaacc aaccttagca agggccttct gagtggaagg aattggccca gtacccatga
     3901 cctctggtgc tacaccagca cttgcataac ctttaatggc tcccagaatt ggaagaccaa
     3961 gttcttcagc tttgtcacga ctcatgagaa ggacagctgc cgcaccgtca ttaattcctg
     4021 aagcgtttcc tgcagtaaca gttcctgaac catctcggac aaaggccgga caaagggctg
     4081 ttaatttttc aagggttgtt ccagctttaa tgtactcatc ttctgccacc aaaattggat
     4141 cacctttacg ttgcggtact ggcactggaa taatctcatc tacaaagcga ccagcggcct
     4201 gcgcagcagc agctttttcc tgactagcca aagcaaatat atcttgagct ttacggctaa
     4261 tcccatagtt ttttgcgata ttttctgctg taattcccat gtggtaatca tgaaaggcat
     4321 ctgtcaaacc atcattgacc atagtatcaa tgatttttcc atcgcctaag cgaccacccc
     4381 aacggtaatc tttgagcaca tagctggctt ggctcatatt ttctgtccca cctgcaataa
     4441 tgatatctga atcaccacag acgatacttt gtgctgctaa ctcgatggat ttgagaccag
     4501 aaccacagac catatccaca gtgaaggcag gtttgtcgtt tggaatacct gcagttatcc
     4561 ctacctgtct agcaacattt tgaccgagtc ctgcatggag gacatttccg aaaatgacct
     4621 cgtcaatttg ttcaggcttc acacctgatt tctctagtaa tgcttctaca accacttttc
     4681 ctaattgaac agccgagaca gatttaaagg ctccaccaaa tgaaccaatg ggtgtcctaa
     4741 cagctgtagt gataacaact tctttaacca acatgcgatt ctccaatcta tttgttatag
     4801 aaagcgcttt ctgtttttgt gaatttattt tatcactact aaaagcgttt gcaaaattcg
     4861 atttttttat atgactataa aaaattttta ttatttttta ttgacagcta taaaaattat
     4921 tattagtatg aagaaaaaga catctgaaat gaaagaagag gcaatatgga tattaaacat
     4981 ttacgctttt tcattgctat tgtagaaaat aattttaacc tgagccgtac cgctcaacag
     5041 ctttatattt cccagcctac cctcagtatt atgattaatg attttgaaga aaagcagggc
     5101 attaagctct tcaataaaaa atacaataaa atcctcggct taaccatgac aggcaagcaa
     5161 ttttatgagg attctttgga ggttatccgc aaatatgaca agatgcacca aaatctcttt
     5221 tccaccaatc aaaagttgga cggtaatatc actatcggca ttcctccatt aattctgtca
     5281 attgtttttt caaaaatcat gccagaaatt attctagaaa atcccaatat ccactttaat
     5341 attaaggagt atggtgctaa tcggctacgt caggaattga ttttagagaa tgtggatatc
     5401 gccattcttc tgcatcctga acgaattgct gcaaacacca ttgattcttt ccaaatccaa
     5461 gaatctgagc tctgtgcatt tgtctccaag aaccaccatt tggccaataa aaaaatcctg
     5521 acttggatag aactccacaa tgaaaaacta gctatatttg ataaaacctt catgattcac
     5581 catctcatca aggaaaaatg taagtatact gacattaacc cccaaatcat tctggaatca
     5641 gcttcttggg actttctgat caattctact cgtatcaacc ctcaactaat gacgattatt
     5701 ccaaaaccaa cggtagatag ctatggtttt caggatattg tggctattcc tatggagaat
     5761 cctattcctt ggaaagtcat ggttagtcgt ctcaaaaaag atcattattc caccatagaa
     5821 gaatacattt tcaacaaaat gcttgaaaaa tttcatgtaa tcgaatagag actaacaagt
     5881 gatccctttc acatgactgc acgtgccctt cgacatatgg cacctcaact aacccttagc
     5941 gcatatggaa acagctcaat tctttttgaa ggataaaact aaagaggctt gacgatccat
     6001 actaactcag acccaatatt attatcaaga tcctaaatat taacacaact catttataac
     6061 aattaactta caaaaaatgg tctactcctt tgaggcgtga cagcaatact gcaatttata
     6121 aaaaatgact gtcaagacaa tatctctgaa ctcagtcact gtttctcaaa aatcactcac
     6181 atctaatgga gtactatcaa gaaaaagtta tttttaaaat catcaataac ctatctaaat
     6241 tttctaaaca atgccatata aaaagagctg gagtcaccaa gctctaattg atttttacat
     6301 gatgctctat aacaatatcg tttaaagatc attctttttt actagtatgt tgatcacatt
     6361 ttctaaaagc cagaaagaga cttgaatacc gagtcccttt tctttttatc tataaacagc
     6421 cttaaagaag cccagacagg ctgcggtaat tttcttaaca tgagcttcta ctatttctct
     6481 tgttaagccc tgctcacttg atgattcgtt atttttacca cctgaagact ctcctctaca
     6541 taggctactt tgtcatctag ttcctgcttc ttaacgatat atcatcgtct caattgatgc
     6601 cacttccctt atcatcttag aaaaaagcta atttctatac ctttaggtgt tctagatcac
     6661 aaaatagctt tctcaatcct atctaccttg caagaattca ttgaatgccc ttaacttttg
     6721 cagtaacgac aataaaaata gtttagataa cgatgctatt gatgttactg acttaccctc
     6781 tttattgata agtatgctaa atataagcaa agaaatgcaa aagctaatct aatcatgaca
     6841 ataactaatc catcaaccca aaaactgcca aaaaagccgt cataagcaag cttaagcatt
     6901 atgtttggtg tactcgcagt tgatacagat aaaatactca acaccttatg aggtattcct
     6961 gcttggaaaa tatccataag aaaacttggt acaaaaacac tagccgcaga caaggcaaaa
     7021 cctgtcaatg gagacttaac cttacttgaa ataaggatag tgatagccgt aatcaggata
     7081 agcccaataa actgataggt gactagattg ataaatgttc ccaaaagagt cattttttct
     7141 ggaaaagcca ttatattcac attgctgtta atccaataca gattgagttg aacactcgtg
     7201 tcccaaccac ttaatccaaa ataccaaaca aagaccgcta atattatggc gtaaaaagta
     7261 acaaacactg aggtgcttat caagtaacta cttattatct tggctatcgt aagtttatta
     7321 cgaccatacc tagttgtcaa taaaatagga ttcatatttt tagcagtatc accggaaaaa
     7381 acaggagcga tgaagtaaac agacaaaaga agaagaagga tataagcact atttatgacc
     7441 agaaaaagct gattccaggg tgcaaaatta cccaacttca gctctttaaa gggaagataa
     7501 gagccaagag ccgtttgaga ttttggggtg atcttactga aatcaatagt ctcttctttt
     7561 ttcaaattaa aataataatc tctaaatttt ggatcaaaat ggctagttac atagtagcca
     7621 tacacattga agacaggatt ttttgagctg ccacctagag tataatcttt gattgttcta
     7681 attaataact cattggacaa ttgaccggta tgttcttccg caaatcgctt gtttatctca
     7741 acagcatctc ttccatgaat tttatctatc gaagaaccac tgatttgtcc attaaaaaag
     7801 ttgatataaa ataacccaaa gattgctaat aagctaacaa taaacattcc caaaactgat
     7861 ttggttcgga tcagtttttt taattcaaat ggtaagagag ctttcataac acctgttcct
     7921 ctctaaagtg ataaatgtat aagtcttcta aggttggtga cactagttga gccaactgat
     7981 ttggtttctc atcactaacc acacgaaaaa cacgactaga tgaaactagt ttctcattga
     8041 ctacagcata ctgaccatgc cttggtaacg gcgaaccatc agagacagaa aactcccaga
     8101 ccttgccaaa gatggttttc aacaattctt gactactact cttatggata aattgaccat
     8161 tttttaaaat gataatctcc ttagcaatag cctcaacatc agagacaata tgagttgata
     8221 agataataat tttgttggcc gacaattcgc taataatatt gcgaaacttc accctttctt
     8281 ttgggtctaa tccaactgtc ggctcatcta aaatcaagat tttagggtca ttgagtaagg
     8341 cctgggcaat accgagacgt tgcttcatac caccagaata agaggcaatc cgcttcagac
     8401 ggacatcata tagatccaca agttttaaca attcatccgt ttcttgcttg gctttatgtt
     8461 taggtattcc ttttaaggct gccatataaa gaagaaagtc tcgaccagaa aaacgaccat
     8521 aataactaaa ctgttgaggc aaaaaaccaa tatgctgata aaattcctct gattgaggtt
     8581 tgtgatccag taaaatctct ccttcatcag gagtcgtaaa atgactaatg agattgagca
     8641 aggtcgtttt ccccgtccca ttagccccta aaagtccgta aaggcctggg gtgaattgag
     8701 tagtaatcct tcgcaaaata tttttcgatc cgtagctctt actcaattga tttaattcta
     8761 ataacataga accctcctta aatgagtcta ctgagcacct gtaactcagt actcagtaga
     8821 cttctcctgt acgaaatcct gctgtctgta acctttatta ttctcgtagc ataatcaaat
     8881 ccagagattt tcgattcatt aatgaaatat tgacgatgac acctttttaa tttcccagca
     8941 ctttctccct caatctgtct cagtgacgta gctgccccaa attccccttt tagggtaaca
     9001 aatactactg tgtgaggctt agatgaatgt gttgtcacat cataggtttc agagattggt
     9061 aatttaacaa ctgacctatt cttatataaa ataacatatt tcattgacgt cctccttctc
     9121 tatttatatc ttaatacaag tacaagcatt gagacggtaa agtctcaaat ggtatctatc
     9181 atatcctgaa tggtatcaca gtagctgttt aagatgtcat agaggcattt gagaaatgta
     9241 acctgttttc ctttcgtttt ttgatcatat gatattgtat tagttcggag aaccatggta
     9301 atcattcaaa tcttacataa acctctcttg ggatatggta ttagcgtcta tattaattac
     9361 tacttcaaca gacacctttt taaagctgct aaaattgtca gtggcaaaca aataggctat
     9421 aggtataaat ctcacactta ttttatcata aaatcattct ttttatcatc taatcaaatg
     9481 tacaagcact ttaaagttat tctcatgact ctattattct tattggaagc catattaatt
     9541 acgacgacat tttcagaaat cattatcgtg tgtttggtat catcgacaca accgctaata
     9601 aatcgtttaa atgtatccaa aaccaaattc atgattacct gttcaaagaa taaccagagg
     9661 gcttactgat tgctttaaca aatatttcta gtcttctcat tttgtactca tataaactca
     9721 tctactctat taaaaattgc tgtgaacaga aaaaccttct caacctgttt cagttttata
     9781 gccgtagtta gtttaaagtg aaaccaccct gcattttcta tacctaaatc caattgactt
     9841 gctttttcag catcaacagt catgctatcc ataagataac acaccacgat gtgttgtgat
     9901 tattgttctt ctatatttag ccttacctcc tgaaaacaaa aaaagagaac accttttaaa
     9961 tgttctcata taagcaatct tatatattaa atgaggattc gatctaatga caagacagcc
    10021 ttattgctac caataatgca gcttaccaaa caagggcaat cagtataagg gttgctaacc
    10081 agctctgctg acatagcctg ctttgagcga tcaatactcc ttctgattat agccaaagtc
    10141 agctaaatca agctttttgt cacgccagtt tttcttaacc ttgacccagg tctccagata
    10201 gaccttatcg cctagcatta gctcaatatc acgccttgcc agcttaccga tttttttgag
    10261 catggcgcct tgttttccaa taataatgcc tttttggctg tcacgctcta ccatgatggt
    10321 aactcggata tgcaccttgt cagtcacctc atcacgcttc atcgaatcga ccacaacagc
    10381 aactgaatga ggcacctcct gctgtgtcaa gtgaagcacc ttttcacgaa ccatctcaga
    10441 aacaagaaag cgctctgggt gatcagtgat ttgatcctct gggaaatact ggaagccctc
    10501 ttcaaggtta tcctttaaga gctgaacgag cgtttcgacg ttgtttcctt gaagtgctga
    10561 aataggaaca atttccttaa agtccatctg actacggaaa tcatcaatct gctccaataa
    10621 ttggtctggg tgaaccttgt caattttgtt gatcaccaaa ataaccggaa tacgagcagc
    10681 cttgaggcgt tcgataatca tatcatcacc cttaccacgc ttttcatcag caggcaccat
    10741 aaaaagaacc gtctcaacct cacgcagggt actataggct gattccacca taaaatcacc
    10801 taaggctgtc ttaggcttat gaatgcctgg cgtgtcaata aaaacaattt gctctgtctc
    10861 tgtggtatag attcccataa ttttattacg ggttgtctgc gccttatcgc tcataacggc
    10921 gattttttgt cccatgacat gattcaaaaa cgttgatttg ccgacatttg gtcggccaag
    10981 aatggcaaca aagcctgatt taaacataag ctactaaggg cctaaaggat cagtcaaggt
    11041 aagaatcaag cagcaggcta ttcacctgat tgctttccta aagcttatac tcctttcctg
    11101 cgctgcacta tcgcacagga tagcccattt cctttcattt ttttaatggc ataacattcg
    11161 ccaaattttg ggaacaaaga taatcagccc cgtcaaaaca gcatagcctg aaatgaccag
    11221 gacagcacct gcagccatat ccttggcatg cttagccagc atggagaaat ggtaatcact
    11281 tgccaagtca accacatttt caatagctga attgacaatc tctaaggtaa tcaccaaaaa
    11341 aatagccagc aataaaaaca gccattctat agcagaaata ccaaaaacaa tcccagccaa
    11401 agaggctaac agggctgaca aaagatgact tcttaggtta cgctcctcct taaaggctgt
    11461 cagaacccct gtcaaagcaa attctaagct ggcaattact gttctgtttt tccatttgcg
    11521 tttattattg tcttgtgagg ccataagcag tcaaaatctc ttcctgtaac gtaaacatct
    11581 ctttttcttc ctcaggagtg taatgatcat aaccattaat atgcaaaaaa ccatgaacag
    11641 ccaagaagcc catctcacgc tcaaaggaat gcccataggc ttctgcctgc tcatgggctt
    11701 tgtcaacaga aataaacagc tccccaatat aagcatcaaa ctcctgtatc atacctgcca
    11761 agtcaggatc aagctccaaa tcctcttggc taaaggcgat cggaagctct ggcttgtact
    11821 ccagagaaat cacatcagtc ggacgatcag tatcacgata ttcaagattc aaggcgtggc
    11881 ttctatcatt ggtcacaaag gtaaccgcca tttccttgtc ctctttacca attgttttgg
    11941 cagcaaaatt gagcaaatca atggtttgct ccatcatctc ttgagaaacc tgcttagttt
    12001 catcaatcat ctctatatac atcattatat gaagaggtcc tagcaagaca ggtccaaaca
    12061 aacaccacac tgctaggtca aaaagcttga tacctcttat cctttcaaca tcatttcagt
    12121 actttctttc cattatacca caagaaaaaa gaaaaagcag gcattagtct agcctgctcc
    12181 aaaagaagcc ggaataatga caagatcgtt gataccccag cagctgctgt ttctggaata
    12241 cccagagcct gctgcgcaga atacagtcct cttagatagc tgggactcct aggattacaa
    12301 tagtagataa gcctttagac cacttccatc gcctaaaaac taatcctaaa cggctttccc
    12361 ttagatacca ctagctgctc tcaaagctat tgtggaggta acgatctggc ttattggctg
    12421 acgccagtga tttctgcttg tcataatctt ctttggttaa ataatagtgc agcactgtca
    12481 caaaacggtt ggaatcaagg tgatcacgct tagcatatgg ctcttcatgt gaaaagcaca
    12541 tgccgctttt agccataaca cgtcccaaag ccggattggc tttatcatgc ttagcaatca
    12601 cacaattcat gcctaaagct tcaaaacaca agaccagtac agccttgaca gcctctgtcg
    12661 catagcctct tccccagtga tgcttatgaa gacaatagcc aatctcagct ctacctaaat
    12721 ccagctgtat atgatgaaga tcaagcgtcc caataaagtc tcctgtttcc tttaacacaa
    12781 tcccccaccg tccaagtgga ctagccagat agacagaagc aatgacttga cgggtctcct
    12841 caattgtctg attggctgga aagctatacc tgacagtctc ttcatcagaa gcataatcaa
    12901 acatggcttt ggcatcatcc aaggtcactg gacgcaggca tagacgctct gtctcaagat
    12961 acctatgctc tgctagtttt tcaaaaaagc ttgccactac tactctccct ttcctaaaaa
    13021 tctaactcac ctaacagcat gactgcctgc cctagccgcg taaaatctgc ctcaccttat
    13081 cctttaaaac aggaaccagc tcctcttcaa accaagcatt tttagccaac caaagctgat
    13141 ttctaggaga tgggtgaaca aggggaaaat aatccggaag atagtcctca aaatgctgca
    13201 ccgtttcggt aagattgcgt ctacaacctt caccaaggta atattgctgg gcatactgtc
    13261 cgaccagcac caccaattca acctgaggca tcaaggccat taacggacca tgccacttgg
    13321 cagcaaagcc ctttcgcggt ggtaaatcac ctgattttcc cttaccggga taataaaaat
    13381 ccataggaag aacgccaaac aagcccgact gataaaaggt cctgtcatca acacccagcc
    13441 aagctctcaa gcgaactccg ctacgatcat tccagtacag acgcgtctcc tgagctacaa
    13501 taccaggcgc ctgaccaaca atgactatcc gagcggtctg aggagctgca taaagtggtt
    13561 cgataccttt tttggtatag tcacgattgg caggatcagc cataatcgct tgcaatagct
    13621 ctgtcatgat accctcactt tcataaaagg ctcttcaggt gaagagctct tttttacgat
    13681 ttgtcttctt taggcagctc tccaatgacc tcataggttg ttaagcctga cgtagactga
    13741 cccgtctctg ttttaggccg atctggagcc ttagtctgat gttgcagctg attagggctg
    13801 ctttttaatg actctgcttt tgaacctaca gtttcatagg ccttaataat ctcagcaaca
    13861 acagggtgac gcaccacgtc cttggctgaa aaatgcacaa aatcaatctg cttgatggcc
    13921 tgcaattttt gagctgcatc aatcaagcct gatgtgatat gacgcggcaa atcaatctga
    13981 ctaatgtccc cattaacaat cattttagac tgaaaaccaa gtctggttaa aaacatcttc
    14041 atctgcatga tggtcgtgtt ttgcgcctca tctaaaatca caaaggcatc atctaaggtc
    14101 cgaccacgca tataagccaa gggagcaatc tcaataatat cacgctccat taaccgagta
    14161 gtctgctctt taccaagaat ctgataaagg gcatcgtaga ctggtctaag gtaaggatca
    14221 accttttcct tcaaatcccc tggtaaaaag cctaagcttt ctcctgcttc aacagctggg
    14281 cgtgtgagaa tgatccgctt aacctgacca cgctttaaag cagtaactgc tagcgtaact
    14341 gctaaaaagg tctttcctgt tccagccgga ccaataccaa ataccacatc atgatgcttg
    14401 atactatcaa cataggcctt ttgccctagc gtcttaacac gaattggctt gctataaaag
    14461 tccttgataa tctcttcctc ataaagagca acaaattgat caagcctatc tgaatccgcc
    14521 atagacagcg cagtcaccac atcagaggta ttgataacca tgccacgccc caccaaaact
    14581 aaaagggctt gtatcgtcaa acgcgctagc tcaacagccc gctcatcatc accaataatc
    14641 tgaactcgct cagttctagc atgaatcaca acattgaggt gagattctat catcttcaaa
    14701 tggcgctcat tgctaccaaa aagagctaac agatcatctg ggtgattcaa gctaatgtca
    14761 gtcgaataat gcaaatttgt cttccttttc catctataag taactctatt ataacaaatt
    14821 ttgctataaa tcgggaataa gacccagctt taaagcctaa aagagctagc ctatggctag
    14881 tggctaaggt aatcctccca aatctggtca aactgcccca gattgaatga aaagctcgct
    14941 tcctcttcaa ggtaacgact gatggtctca aaatcatctg tatgctttgg aaaggtcggg
    15001 tcctcaaaaa ccaaatcagc taataaagca gcaggcttat tagatgtcga gttgcgctga
    15061 gccatcagcc aagtgtaaaa cgcctttctc attgccaatg ctcctccaaa aattgatgac
    15121 gaatagcact actttgtgca taacgctctg gattcttttg ataaaagccc tgatgatagt
    15181 cctctgctag ataaaaaggc tctgccggtt caatgcttgt cacaatgggc tggtcaaagc
    15241 gccctgaggc ctgcagggtc tgcttggacc gctctgcaat ttcccgctgc cgctcatcag
    15301 tatagtaaat caccggccga tagttgtctc ctctatcctc aaattgccca aaggcatcgg
    15361 tcgggtctgt ctgagcccag taaagctcta ccaaatctga atagctgatc agactcggat
    15421 caaagataat ctcaacagct tcagtatggc ctgtcgtctt tgagcaaacc tgctcatagc
    15481 ttggattgtg aacatgccct cctgtgtagc cacttctcac tgataaaata cctgcctgct
    15541 cctcaaaagg ctgcaccata caccaaaaac agcctcctgc aaaaattgct ctttccatac
    15601 ctaatctcca ctttctttgt ccttacatta gtgattttca ttgtaacaaa aaaccttgcc
    15661 agaggcaaag cttaatataa aacaagtcac agactcaaag taacaagact cctcagccca
    15721 actagtgcct agcactaagc agtactgtca agcagccact actagatcaa gagggccaca
    15781 cagagctttt tcgacaacaa aaatgattgg cgctttaaaa caggctatca gctaagctcc
    15841 acactcaaaa taaggaagct agctatactg ataaaggata agtcttagca acaccgatcc
    15901 agcttatgat tataggctaa gagacagaca gctccctatg atatcagctc agttcctgtc
    15961 acgtcctgct tgatcttgtt agccttcatc aaaccaccta aggccttttt aaattgaccc
    16021 ttggaaatcc caaaggttgc cttgatatcc tctgggcttg acttatcatt aagagtcatg
    16081 tagccaccat tagacttgag ataggtcaga atcatctggg catcgttttc cagcatttca
    16141 aaggaacgcg gctttagcga aaggttgagg gtacggtcac gttctctaaa gccaatcacc
    16201 cgagcggtca aaacctgccc caaacgaggc tccgtataac gctcgctagg gtggataaag
    16261 cccagcatat tattttctgg caggtaaaca aaggtccctg atagcttcaa gcgatagaca
    16321 atagcaggca ggctttgatt ttgcatgtta tcataggctg gactagcaag cctttgaaat
    16381 atctctggct cagctggcaa accccagata cgatcttttt tgtcaaccac aagcttaaga
    16441 taaagcctgt ctcctttttt aggccaaaga tcctttagct ccggcaaaac atctaaggaa
    16501 accacaatct ccttatctgg aataccagta tcaacaaaca ccccaagatc acgacggaca
    16561 gtggtcacct cgccccagcc ataatgatca cgccttgcgt caataggctt cgtggtcaag
    16621 cgtagtcttt gcttcatatc tgtatagaca aagcccttaa ccatatctcc taatctatga
    16681 ctgccttcct ccttagctag agcaaagctc agcccctcct tttggacaag ataaaactga
    16741 ctattttctt cttttactaa gccagtgata actgttgcta ataaatgatt catatctttt
    16801 tgttctttct tttaaaaaat agggacaagt ccaaagcagc tgctttttag ccttgtcacc
    16861 tatcctgtta tgcctgatgt gtattaggtt acgcagctga tctagcttaa tgatcagata
    16921 agccgcttaa actgaaagta attccttttc tttgtcagca gtcattcggt caatctcttt
    16981 gacagcctca tctgttgctt tttgaatatc cttttccaag gcttttaact catcttcagt
    17041 gatttcctta gccttctcct gctttttagc ctcgtccata gcatcacgac gaatattgcg
    17101 aatcgaaacc ttcgcagtct caccaacctt tttcacttcc ttggctaatt ccttacgtgt
    17161 ttcttctgta agcgctggaa taaccaagcg gatgacagag ccatcgttag ctggtgtaat
    17221 gcccaaatca gaagcattca aggcacgctc aatatccttg attgatgatt tgtcaaatgg
    17281 tgaaatcaaa agcacacgcg cctctggtac tgtaatagaa gccaattggt tcaacggcgt
    17341 tggtgcacca taataatcca cctgaatacg atccaaaagg ctagcattag cacgacctgc
    17401 acgaatgctt gcatactcgc gtgctagtga gtgatgtgac tgtgtaaaac gttctttcgc
    17461 agtttcaata attgcatttg ccatgattgt ttttctcctt aatcctttag ctctaaaatc
    17521 ctaatcgcag gccttatttg ataccgttgt gccaatatgc tctccaaaga ccacacgctt
    17581 gatatttcct gcttcattca tattaaagac aaccaaatca atatcattat ccattgacaa
    17641 ggttgaagct gtcgcgtcca taatcttgag accgcgcttg ataacctccc catgagtcaa
    17701 ttcatcaaac ttaacagcgt ttgcgtcctt tcttgggtca gcattgtaga caccatcaac
    17761 accattttta gccatcaaga tagcatctgc ctcaatctca gcagcacgta aggccgctgt
    17821 cgtatctgtt gaaaaataag gtgacccaat accagcaccg aaaacaacaa tgcgcccctt
    17881 ttccagatga cgaagcgcac gacctcgaat ataaggctct gcaacgtttt gcatgggaat
    17941 agctgtctgc acacgagtat caacgccata atgctgaagg ctatcagcca ttactagagc
    18001 attcataacg gttccaagca tgcctgtgta atcagcctgc acacgatcca taccagcctc
    18061 tgcagcaggc tcaccgcgcc agagattacc accaccaata acaagagcaa tttcaacacc
    18121 tgaattgtga acttctgcga tctctttagc aatcgactga accgttgtta tgtcaatgcc
    18181 aacaccctta tcaccagcca aggcctcgcc agacaatttg attaaaatac gttgatattt
    18241 aggtttcact atttatgatc tccttatttt gtccctacca ttctaccaca aaacaaaaaa
    18301 atttaataga ccaatgcaag agaggaaagc gaaatttttg acgatccttt tatcaagatc
    18361 cctttgagca gcaaaaaaga tgagtcatta taaaaagagc attatcgtat ccgaatagca
    18421 cagttataac ctattaatac gacaaaaacc agaacaacta tgacaaaaaa cgccgtaaaa
    18481 aagacttaaa atcaagcctc aagccagact agattctaag tcgtgctata ttgagagatg
    18541 atttgtttta gttatctagc ccaatgccgc cacaagaagt ctgaggctcc ttatctctga
    18601 cagcaactag cctcccctgc tccagcagca gaacacgatg acaaatggcc tgacagatat
    18661 tagcatcatg cgcaataaaa atataagtca gttgatactc ctgctttaac tcatagagca
    18721 agtccaatag ctgcccttgg gtaatagggt ccaagccact caaagcctca tcaaaaatga
    18781 tcacctccgg ccttaacaaa agagctctcg ctatacaaac acgctgtagc tgaccaccac
    18841 tcagctctct ggccttttta cccagatgag tggcgtcaag accgaccgca gctagtattt
    18901 gaacaacctc ctctaaggca aagtccttag aaagggcctc tgtcaatatc tcttgaatag
    18961 taaagagggg attgactgat cttagcgcat cctgaaagac aagtaaaatc cgaggtccac
    19021 atacttttac agaatagggc tgaccatgaa agagcacctg accagctgtc ggctgctcta
    19081 gcccaatgat taacctagca agcgttgtct tgccactacc actttctccc ataatcccaa
    19141 ggctctcacc cttttccatt tgaaaatgac aatctgttag cactggcttt tgatgaaagc
    19201 tcttataaac atgtctaaac tctatcatag cgtatcagcc gatcataatg attttgcaaa
    19261 agcaactcct tggtggcagc ctgacttggc cgatgaaaaa tcgactcaac acttccctgt
    19321 tcgatgattt ttcccttact catcaccagt agttgccctc ccaaagtctg tgccaattgg
    19381 taatcatgcg tcactgtaat aatggttttt cccttgtcct gcaataactt cagcatccgt
    19441 atgatattag aacgattggc atcatctaaa gcagaggtag gctcatctaa aatgataatc
    19501 tgtgggtcta agcacaacaa aatagctagc attacccgct gtagcatacc accacttagc
    19561 tcaaaggggt acttcctcag cagctcctct ggctgctcta gatagagctc tcgcatgaaa
    19621 ggcagagccc tttttagaca ggcccttttt gaaagtctct catggcttcg gatggtttca
    19681 aggagatgag cctcaatggt ctgaaaggga ttgaacatcg ccataggatt ttggaccata
    19741 taggccatgt ggcgccctct aatgctctgc cattgcttag catctaattg atctagtctc
    19801 atatcttgac aggtaatcct ccctgtcatc tgtacattcg acgggcattg accaattaat
    19861 agcttagtca agagggtctt gcccgaacca ctcctgccaa caatcaccaa ggagctcccc
    19921 aagggcaact caagattgag cttacttaat agcacatcag agccattata agccgataaa
    19981 tcattaacaa ttaaccgttc catgttttcc tccacccctt agcatcagcg taatcaccta
    20041 ggctgttaaa agctagcaca gtcactaaaa tggcaagccc tggtgacatc atgagccaca
    20101 gagctgtcct aaaatagctc cttgcatcat gcagcatcat tccccattct gtcacattgg
    20161 gctgaacacc gatacccaaa aaagaaaagc ttgagatcat gagaataata ttgccaatat
    20221 tcatcaaagc caacactaca atcggccgat aaacaaatgg caggatatgc ttttttaaga
    20281 tatgccgcac agataagccc attgtctgcg cactaatgac atatggctct gccttagcgc
    20341 ttttgaccat cgtgaccatc agcctagcat aatacagcca ctctaccaga acaatagcta
    20401 ggatcatgtt gcctatgccc tgcccaagta tccccattgt agctagcgat agtaaaaagc
    20461 taggaaaggc agaaacaaca tcagctagcc acagaaaagc tgcctcgagc cttccttgat
    20521 accagcctac aaccaaacca accacagcac caatagatag ctctaacaaa ctaatagtaa
    20581 ccgccaaaag caaggaatac ttagccccat ataacaagcg cgacagcaca tctcttccca
    20641 attggtcagt tcctaataag tgctgctgac taggtggcat gagcttacta gcaacatcaa
    20701 cagcatgagg atcaaaggga gcaagataag gagcaaacaa gacacagata aacaacagca
    20761 atagcataac agctgaacca attacgtatt tgggcatgct tcctcctttg tcttgcgcag
    20821 acgagggtca ataaaagaca ctagctcttg agttatcaca tggtgtagta aaaacaaagc
    20881 accaaataag agcatacagg cctgaataac cggaatatct gctgctttca gactcataac
    20941 aaatagactg ccaataccat tccatgagaa aatatcctca acaataatag agcccgtcat
    21001 caaataaaca aaggtcaagc tcaagcctgt tgcaatagca ggaaaggcat ttctaatcag
    21061 gtgatgctta acaatataat aggtcttaac ccctcttagc ctggcatttt caacatgcag
    21121 actcgttagc tgctcactga ttgcctttcg tatcaaggca gtatattgcc caatcaagga
    21181 aaagctaagc gtaatactcg gcaaaatgag gctgctggca cccgccttgc ctgacacagg
    21241 caggagattt agcttaacag aaaaggctat aatcaagaga tagcccaacc aaaagctagg
    21301 cattgacaca gcgacaaagc tgaataaacg caccagccga tcaaacaagg aatgctcaaa
    21361 caaaccactg cctaccccca aaggaaaggc aatcacaagt accagtaaaa aagaggtcaa
    21421 gcttagcatt agcgttgcta aaaagcgctc caccaccaaa ggcaggacag ggacctttaa
    21481 cacgtaagag gtcccaaaat ttcctacaag aatgtcagat aaccaggtca catactgctc
    21541 ccataaaggc ttgtctaagc ccaaatagag cctagcattg tgaagagctt ctggtgtaat
    21601 actgatctta gataggcgca aatactgctc tgccgggtta gcggaggata gcttaaccag
    21661 aacaaaggtc actatcgaaa tcattagcaa ggcgccaaag gtagaaataa gcttcttcat
    21721 catattttct ctcaaccctt cactaagaca tcagacaaga attgtcagga tagtcactca
    21781 caaccagttc ctctgctcta tcaattcttg actgccttat cagcagcact tttttcaatg
    21841 taacgcaatg gaagggcatt ttcctctggt gcaaagcgca ttgtcttaaa atctcccttg
    21901 cgatatactg aaacaactga ctgataggtg agtggaatat aaacagcctc atcatgcaac
    21961 aatgacaata cctgcttata gcccttgtct accttatccc catctggctc aatcaaaaca
    22021 gatttaatca ggcgatcaat ctcagccttt gatggcaaac tctccaaggc aatattttct
    22081 gggtgaccat gatccgcttt tgccgttaag gctgtcatcc aagcatgagg atcccaagga
    22141 gctccccatg aataggtcag catcatatca aactgccctg tcttggcatt agcccagtag
    22201 tcatcctcct ccatagctgt caagaccaca tcaatcccaa gctttttcca ctcgccttgg
    22261 aaatattcaa ccaaatcctt gtctgtcgct ttagttgaaa tataaggcac ctgtaaacgc
    22321 aactgctgac catctttttc cctaatccct tcttggtttt ccttccagcc agcggctgtc
    22381 agcatgtcct tagccttttg gagattgtat tcataaggaa ctaagcccgc atcagcatgc
    22441 ggtgttgttt ttgaaaaaat ggtatctgct gctgtctctg ttcctctaaa ggtgtgctta
    22501 gcaatagcct ttttgtcaac cgcatggttc attgcctgac gaacccgctt gtcctgaaac
    22561 actgactgct tagcatttaa cagcaataaa cgagtcgaca tgggctgaga aacatcagta
    22621 acatacttct tgtccttagc atactgcaca aaggtatcaa gactaatcag accatttcca
    22681 tagatcaaat caatatcccc agcctcaaat gctaaggctc ttgtctcagc atcaggcata
    22741 atcttgatgg ttacttcctt tagctttggt ttttctcccc aatagctctc atgacgtgta
    22801 aaggtaatgt actcatttgc ctttttctct ttaacaaccc attgacctgt accaatcggc
    22861 tttttaacat tgtgcttatt ggtgtcatcg ccatcaggaa aaccagcatc agccaaaaac
    22921 ctaatcggtc tgatcattga caaatcatac aaggtagcgc tataagcctc ctttagctta
    22981 atctcaaagg tatgatcatc taaagccttg tagctatcca attgattggt aaagtgaaac
    23041 caattatgat tgcccttatt ctgctcagag aaaatcgaat caaaattccg tttaacattt
    23101 tgagcattaa aatcagaacc atctgaaaat ttagcctgtc tcaggttaaa ggtataggtt
    23161 ttgccatctg ggctaatcgt ccagctctct gctaacgccg gctcaatatt acccttgtca
    23221 ccatatcgaa ccaagccctc ataaaccatg tcttgaataa caaactgatc aggattgtag
    23281 cgatgaggat tgacatcacc aaaatcctca ccccaagcaa tcctcaactg atccgtacgg
    23341 taagaggcct gcttagcatt ttgacaggcc gtcagcagca aagcaaaaaa gaataacaat
    23401 agcacattca atttagtttt cattatgtca ttaactttct aaagatatta atctatctaa
    23461 ttttagatgt ggtttatcac aaaattaagt atggttaatt taatcatttt atagccctct
    23521 tgtcaagaaa aaatgagaca aaatcagcct agaaaaagcc agaaggctac aaataagcaa
    23581 atcgtcaaaa tcatgaacac ttcaggcttg ctgaggaata ttttctaatg gttattagaa
    23641 ataatgaaca attacctaac aaaagactcc aaaataaagg taaaagacga acattcacct
    23701 tgctgctcag ctaccaagac aaacaatcct gatagcatca attttcttta ggctcttagc
    23761 aattagttgc aatatcagat aattttgaat ttaattaaaa aaaacgaaac tacggagacc
    23821 aattatcaga aagctattca cagccagcaa agggcatgct aaagtattat ctggaaaaag
    23881 aaaggcttag gaatgattat ttctaaacta aaaggagaga gacaatgaaa aaaacaatga
    23941 agaagatgct agcagcctcg acgctctgta tcatcatgtc aggcagcttc atcagcggct
    24001 cagctagagt gttagcggag gaatattatg ggtggaatga tgtcactggg tctaagtcac
    24061 catttcctct atacgtgaca ccaaaaaatg gagataaaaa tataaaagtt caacaaacgg
    24121 ttgtttactg ttttaacagg gatgggcaat ggccagaaaa ttgggaaaaa cggatatatg
    24181 aatctcctga taaagttcca cataaattac ccgaatataa taaaaagtca ggaagcgata
    24241 atctgtttca attacttaat cccaaaatta agataaaaaa tccaatggca gctttattag
    24301 cggttttgga agatggatat cctacgtcat cttcttcagg agtaaatcaa agaacaactc
    24361 agctagctat ttggcatttt acagatggat taagcaatct tgcccaattt catcttactc
    24421 cggaagaaac ttcagcttat aacaagttga tagaaaaagg gacaaatgct tctaatcaaa
    24481 gtgaaaataa actattaaat aaaactttag atatttattc ctatatagat gggactggtg
    24541 ataagaaaca caattatcaa caccttcttg gctccactcc aattcctatt gataattcta
    24601 aagaaaataa atgtcaatgt acaaaagttg acttaatgcg aactggagat ggggttaaaa
    24661 tcattgttta tgttgataac aacggaaata atagatatga caacggcgac aaaatgctaa
    24721 aagaagaaac tatcaaacat ggtcaacgcg gacctgctgg tgaatctggg aaaccagggc
    24781 ctaaagggga tcgaggagaa actggagcac gcgggccagc tgggcctcag ggcaaacctg
    24841 ggaaacaagg acctagaggt gataaaggag aaaccggaga acggggacct caaggggaaa
    24901 aaggtgaacc tggaactcct ggtcctaaag gagaagacgg taaagacggg gctcctgggc
    24961 gtgacggaca accggggcct aagggtgaaa aaggtgaccc tggaaaagac ggacaagatg
    25021 gaaaaccagg ggaaaaagga gaacctggaa ttcctggtcc taaaggagaa gacggtaaag
    25081 atggggctcc tgggcgtgac ggacaaccgg ggcctaaggg tgaaaaaggt gaccctggaa
    25141 aagacggaca agatggaaaa ccagggaaaa aaggtgaccc tggacgcgat ggtaaagatg
    25201 gagaaaaagg cgaacgcggt gaacaagggc ctaaaggaga acgcggtgag cagggacctc
    25261 aaggagagcg tggggagcaa ggacctcgtg gggaaaatca tactcctacc ccagacccaa
    25321 tgcctgagcc ggcacctaaa ccagaatcca aacctgaacc taagccgaca cctcaaccag
    25381 aggttaagcc tctgccagag actaaacctc aaaaaccaac caagccgtca gcaatggcta
    25441 gccaaccaag tagcaaagca ctaccaaaaa caaatgacac tagcggctta atgactgtac
    25501 ttggaacagg cttgctctct cttcttggat taggcttcct ggcaaaacgc aaaagaaagc
    25561 aataactaac acataatcat tagtaatcca ttcattatcc atttacaagt tatcataaaa
    25621 aagccttatc attccttgac tggtatgata aggctttttg tttaccctat atagctctac
    25681 ccttactcca aaaatcactt aaccctagga aaaggctgac tatcattttt ggccaaaaaa
    25741 agacagacac caattcatga tgtctgtctc aaaaccaatc ccttttaggg tcagtcctta
    25801 attacttatt aaaatgaact tggatctacc ttgataccca caccttgtgt agttgtgata
    25861 gatacgttag tcatgtaagt accctttgca gtagctggct tagccttaac cattacctca
    25921 tggaaagcct taaagttttc aaccaacttg tcagcgtcaa atgatacttt accaatgata
    25981 gcttgtacgt tacctgcttt atcagcacga taggtaattt taccaccctt agactcttca
    26041 accgccttag caacgtccat tgttactgta ccagttttag ggtttggcat caagttacga
    26101 ggtccaagga cacgtccaag acgtccaaca atagccatca tatctggtgt tgcaataaca
    26161 acatcaaaat caagccagcc gccattgatc ttagcaacaa ggtcatcttc accaacgaag
    26221 tctgcaccag ctgcctttgc ttcttcagct tttgctccac gagcaaaaac aaggacacgc
    26281 tgagttttac cagttccgtt tggcaacacc atcgcaccac gaatttgttg gtctgccttg
    26341 cgaacgtcga tgtttaagtt ataagcaact tctacagaag cgtcaaattt tgcgaagtta
    26401 gtttcttttg cgagtgctac agcttcctct acactgtatg cctttgtgct gtccactttt
    26461 tcaagtgctg cacgcatttg tttgcttttt ttagccattt ttatcttctc cttgtaatgt
    26521 ggtcatatcg atttgattta aaaatctccc acgtcactca tctctatgat gaagtcttgc
    26581 gggtaataag ggcaggttgc tgattaatca gtaacggtga atcccataga acgagcagta
    26641 ccttcaatca tacgcattgc agcttcaatg tttgcagcgt ttaaatctgg catcttagtt
    26701 tcagcaattt cttgtacttg tgcacgagta actgtcgcaa ctttagtttt gttaggtgta
    26761 cctgatcctt tttcaacacc tgcagccttc tttaaaagaa cagcagctgg tggtgtcttt
    26821 gtgatgaaat caaatgattt gtcttcgtaa actgagataa caaccgggat aatcatacca
    26881 gcctgatcag ctgtacgagc attaaattcc ttagtgaatc ccatgatgtt gatacctgct
    26941 tgaccaagag ctggtccaac tggtggagct ggtgtcgctt taccagcagg gatttgaagt
    27001 tttacaagtt tttcgacttt tttagccatt tttaaaaatc ctcctgttgt ggttttggcg
    27061 gtaattcacg atttttacct cccacaggta tgctagagca taccttacca ttatacctta
    27121 ttagacagat aaatcaagtc attttcacaa aaatgttacc gcaaatagca gatgtctcct
    27181 atggcactag cagtacaagc atgtgaggct tccaaggagc cgcttctagt tgacttttaa
    27241 gcgttttttt attataacaa agctatgcat aagaaagtta cgatcaaaga tgtcgcacgc
    27301 gaggcgggag tttctgtggc tactgtctcc tatgtcatca ataacagaga agatcaaaaa
    27361 attagccctg aaacgcgcaa taaagtgctg caaatgatta atcttttaaa ttatcggcca
    27421 aaccaagccg caaaatcact cgtgacacaa aaaagacagc taatcgccct ttactacaaa
    27481 gagcacagct ctgttttaaa aagagcagag cagcttcact ttatcaccca gctatctgcc
    27541 tttctttaca caaagcacta tcacttgatt tgccttaatc aagaatacat cggaaaatat
    27601 gatgtagcag atgtcattct caccctagag gtcaccaaag aggaatttta caagatcgga
    27661 aatagcaact ttgttccttt gattgctatt gatagtatta ttgatgatcc cttatttttc
    27721 cagattaata gtgaccctca tctcctgttc aataaagcca gtgcttattt tgcaggggag
    27781 ccctttgaac tggttagcct gcctattcaa aaccaagaaa tcactcaagg actcgctcaa
    27841 cagtttgata acatttgctg gattcactct atttgcgaca tcgaaagcgt gtctaagggg
    27901 aatattctag ttattgatga tactgtcaat catattctta gtaagcacaa gaacaaacta
    27961 tacctgccaa gtatctcaga agctaagctt ctgaagcttt ttcaggctat tgagtgggct
    28021 tccaaaagag aagcaatcaa caatcataat attttggttt aaccatgata agagcttagc
    28081 aacaagcttg ctgctaagct ctttttgttg gtcaagaggc caactttatt taggtatcag
    28141 tcagtgtgcc agctctttta gccactaaaa gcaggaatta gtttacaagt ctaccaattg
    28201 ggtataaaat agacttatga tcatctacaa attaacagcc ttagccttta ttatcctgac
    28261 tcccttattc tctatgataa tgatatccct attgagactg ggacgaagag gccttaaatt
    28321 tcctgattta gccttaccac tttttgtttt tgaaattgtt attgtatcag gaaaattttt
    28381 cacccatcat ttactacctt attacctgat tgttatgtcc ttgttggcca ttgttatggc
    28441 actcttactg attatcagaa tccagcagtt ttcttaccgc cgatttttca aactattttg
    28501 gcgagtaggc tttttagtca cactactctt ttacctgatg ctagttggtc ttatttttat
    28561 cgtttagtgc cttaccagac atggcttcaa gcctagcagt ctgaatctgc caattaactc
    28621 tagcactatc actcaaaagg aagctgtctt tgaactttct gcttgagtgg gacttttttc
    28681 aaagcaatca atccatatca aaccagcatt agagcatgcg gcttgatacg gattgattgc
    28741 tttaagaact gttgtaaaat atcaaaaatt cagtttttaa taaagtccat tagctatttc
    28801 tacactaaat atcatttaag aaaacagagg ctaataacta gagttcacta taacctaaaa
    28861 tcaccaatac ctccgattaa cttaatttaa ccaaactact gtatatacca aagtttttta
    28921 cgtgtcatta taatacgttc agataaatca tctaatgcac gatctttgtt gagaccaaca
    28981 tcatattgaa tacccattaa tctatctaga aactcaagac gatatttctt cataatattt
    29041 cgtgagtgtc cttctggaaa atgctcatca ataagcgaac ttacaatctc aactttatta
    29101 ctaattttaa aatagcgact tttcaaagat tgtaattctt ctttaattgc tcttaattta
    29161 gaaaaactat ctgctccata aaccttagct tccatttcat tagcctcaga ataacttagt
    29221 tttattgttg caataaaatt tctaagtact tccttctctt ttttaagctc cctttctgtc
    29281 ggactcattc tatagtaata ttgacgccaa cgatattgag aagcgttgac tttttgatca
    29341 cttatagtca aaatagtcaa tgctactaca ctaaagaaaa atattctttt cgtttgcagt
    29401 ttctcctata cttcataatg tactatttgt atataaacac aacataacca agcattagta
    29461 tatcagaaaa ctttcttaaa tatgtgatat tagctaatct ttttttaaaa ctctctatat
    29521 attaaggtat tatggacata ttgacttagc agattagatc tgccaattag ctctagcact
    29581 atcactcaaa atgaagctgt ctttgagttt tctgcttgag tgggactttt tcaaagcagc
    29641 atatcaaaaa cccgtatcaa gccacatggt taagcttagc ttggtacggg tttgttttat
    29701 gatgagcctt tagatgagct cttttttaat tggtttgcag tacctttctt ggcttagtcc
    29761 cctcagctgg accaatgaca ccggcctctt ctaattcgtc cattagtcga gttgctcggt
    29821 taaagccaac cgatagacgc ctttggagca tcgaggcgct tgccttttgc gtttccaata
    29881 caagagcctt tgcttcctca aaaaggggat caccctcagg agctccgctg ctgccataat
    29941 cagagtcact aacctcaccc ggatcaaaat aatcatcata atcagcctct gcctgctcct
    30001 tgataaagct aacaatgcgc tcaacatcat catctgaaat aaaggagcct tgcagacgca
    30061 cagggtgatt ctcatcaatc ggcttaaaga gcatgtcccc gcgaccaagc agcttttcag
    30121 cgccattttc atcaagaatg gtgcgactat ctgttcctga tgaaaccgca aaggcaatac
    30181 gtgatggaac attagcctta atcaatccag aaataacatc aacagaaggt ctctgagtag
    30241 ctaaaatcat atggatacct gctgcacgcg ccttttgccc aagacgaata atagcatcct
    30301 caacctcctt actagccacc atcatcaaat cagctagctc atcaacaata acaacaatca
    30361 tcggcaaagg gatttgcttt tgctcagatt gcttgttgta ggcttcaacc ttggcattgt
    30421 agcctgcaat atttcggaca ccgaccttac tgaacagctc atagcgattt tccatctcat
    30481 caacaacctt ctgaagcgct ttgcttgctt tacgagggtt ggtgaccacc gggattaaca
    30541 ggtgaggaat gtcattataa acagacagct caaccatttt cggatcgacc attaggaatt
    30601 tgacctgatc cggtctagcc ttcattaaaa tactggagat aataccgttg actgcaacag
    30661 atttccctga tcctgttgag ccagccacca gcaaatgagg catgcgggtc aaatcaaagc
    30721 ttctggcact accgttgaca gccttaccaa gaggaatttc caataatttg tcatcagatg
    30781 tgttggattg ctcccaaagc tcgcggaaag aaaccgttgc aacctctgaa tttggtacct
    30841 ctatacccac aagggatttg ccagggatcg gagcttcaat ccgtacgtcc ttggctgcca
    30901 aggccaaggc caagtcatca gctaaattgg aaatgcgatt cacacgaaca ccaacagccg
    30961 gcttaacctc gtatttagtt acagatggcc caatctctgc ccgctccacc ttgacgtcaa
    31021 ttccaaagct tctgaaggta tcctctaata ccttgatatt ttgacgaaca aggtactttt
    31081 ccttgaattg atttttaggc ttatcagcag caaacagctc tatcgtcggc agcttgtaaa
    31141 gcagattggt ctttggcgtg aaatcgacct ccactgacag ctcctcatca tctgacagcg
    31201 gcgcctctcc tgcgattgct gaagcacccg ttagaggggc ttctggtaca gactcctctt
    31261 catctccaaa tgcctcaggc tcatcatcag cagggtgtga gtcataggcc agaatttccg
    31321 gctcaaaaaa tgcttcagac tccttctgat cagccatctc catcaatagg tcttctggct
    31381 ctgctaaaag ctcacctgtc tcaggattaa tcgcttgatt ggccagatat tcttgctcct
    31441 ccaaggcctc tcttgctaga cgctcctctt cagccagcaa tcgttgcttt tctcgctcaa
    31501 caaaccgctt ttccttgttt tcttgatagg ccagggatag cttttcaaaa agcgtcttaa
    31561 caaaatgact gacgtcataa atatcccaag gggtcattaa aaacaagccc agcaggataa
    31621 acaaaaaacc aataaaataa gagccaatat tagaaaacaa gaaggaaata ggcttgtaca
    31681 gcatggcccc aagcatacca ccaccaacaa actcgctaac cttaaaggct agcaggtcat
    31741 tggtgattag ctggatagtc ccagcaacaa tagcctgatg agctagctga ggcaatgaga
    31801 aaagataggc atgccattca accagaagcc ctaaaaacaa gatgataaag ccagcgataa
    31861 ggccatcttt ttgcctgagc cacttgaaga aaaagaggta aaaaaggacc gccaacatca
    31921 agagattggc taagtcgcca accataaagc gaataagatt atataaggta accccaagcg
    31981 cacctaagcg aagcatggca aaaacaagca ataaagcgca ggagaaagaa gcaatcattc
    32041 tcttaatagc cttttgcttt tcaagctctg cctttgttaa acgtctctta gggggatttt
    32101 tttgtcgttg agttcttcta gccatagcct tattataaca ttttttaatc gttatgaaag
    32161 atgacattaa aattctcaat aaatagatga agctgcttga ttttatgcta taatgtcaat
    32221 cataagaaca aataggagtt gaagatggaa aaagaattta acaccttgac ctatggtaag
    32281 cttcccctgc aaattgatat ggggcatggc aagctaattc ccaaaggagt tgaagtcaag
    32341 gctatcgttg atatgcagac cgggcaagtc accttcaagg tttctcagga ggacttagag
    32401 aagcttagaa atagttaaaa aatagacttc gtctcaatgc cctttagctt tattttccaa
    32461 gtcattttat gttaaaataa aagaaattgt tctaaggagt acacatgaaa aaactactat
    32521 cttttggctt aatcggtctt gctttgctta gcttaagtgg ctgtgagtcc attgatcgtg
    32581 ctattaaagg tgatgaatac gtcgatgaaa aaatcgctag agaggaaagc gagacagcag
    32641 caaaggctta tgaagcaaaa atcaaaaaag cactcaaggc tgacgctgat cagtttccac
    32701 aattaaataa agaagtcgac aaagacgaag ctaaggtcat tatcaaaact aatcagggcg
    32761 atatcaccct caagctcttc cccaagtatg caccgcttgc tgttgaaaac tttttaacac
    32821 acgccaagga aggctattac gacaaacttt tgttccatcg ggtgattaat aactttatga
    32881 ttcaaaccgg tgatccaaag ggagatggat ctggcggaga atccatttgg aagggcaagg
    32941 acagcaaaaa agatgcggga caaggctttg ctaatgaaat ctcaccattt ttatataaca
    33001 ttcgaggggc tcttgctatg gcaaatgccg gtgcagatac taatggcagc cagttcttca
    33061 tcaatcaaag caagctcaac caagccaagg ccttatcaat tgataattac tctaagccaa
    33121 tcattgactc ctacgaagaa gggggtaatc ctagcctaga tggtggctat accgtttttg
    33181 gtcaggttat tgagggtatg gatatcgttg ataaaatagc tgccagccca gtcggcccaa
    33241 atgacaaacc aatagagaac atcactatta atgctattga cattgttaag gattactcct
    33301 ttaaaaaata gcctctaagc tacaacaaca ataaaacgac cagctcctta tcggaaaagc
    33361 caccgattca agagctggtc gtgatttttt gctatcaatt aaataaagaa gctagcctat
    33421 tgatcatatc attagcagct atccattcac agccagctat ggtttactag gaatgctttt
    33481 taaagtagcc ctgcttaggc gaaacaaaga agctaatcag aaacaccaca gccgaggtca
    33541 aaacaatgct tgagcctgct gcaatattaa aggtgtagcc caaatagagc cccaacacag
    33601 aggtcatagc tcccaagcat gaggagataa ccagcattac ctttaggctg ttagcataca
    33661 aatacgctgt agccgctggc gtaatcagca tcgccacaat caaaatggta ccaacacttt
    33721 gcatagcagt caccgaaacc aaggtcaaca aaatcatcaa cagataatga taagcagtga
    33781 ccttcattcc catagacctt gctagcacag gatcaaagga ggtaatgagt aattccttaa
    33841 agaagaggac aataatagcc aaaacaaaaa ccgaaacaat gatcgtaatc catttgtcac
    33901 tgtcttgcac tgctaggata tttccaaaga ggatatgaaa aagatccgtt gagctattag
    33961 caatcccaat cagaataacc cctaaggcaa gaaaagagct aaaggttatc cctattgctg
    34021 tgtctccctt gataacagag ttttccttga tgtaggtaat gataacagag gctagcaagc
    34081 caaagacaat agcccctaca aaaaaattaa tccctaaaat aaaggacaag gctactcctg
    34141 gcaaaacagc gtgagaaatc gcatcaccca ttaatgacat ggacctaagg ataataaagc
    34201 agcctactgc tcctgataca ataccaataa caacggctgt aataagggca ttttgtaaaa
    34261 aatgatagga catcaggccc tcaaaaaact tcaaatacat ttaaaacatt ccctttccta
    34321 agaatagatg atcaccatag gcctttgata gggtttcaac agtgaacacc tcatcaacag
    34381 atccataagc gatcagctct ttgttcaata ccactaactc atcaaagtaa tgctctacct
    34441 tgcttaaatc gtgatgaaca attaaaatcg ttttgcctgc ttttttcaag tccttgagca
    34501 ggtcaatgat gattttttca ctaaccgaat caatcccaac aaagggctca tcaagaaaaa
    34561 tatagtctga ctcctgaatc aagcatctag ctactagcat acgctgaaac tgaccaccag
    34621 aaagagattt tatcggacga ttaccaaagc cagcaagccc aacctgctct agcagctggt
    34681 caacctgatc atattctttt tttccgacac gacgaaaaag ccctagccta gtgtaggtcc
    34741 ctaatgagac gcactccttc accgtaattg gaaagttgta gtcaatcatg ctgcgctgct
    34801 ctacataagc aatcgtatgc cccagccttc gaccgtcctt ttgatcaaca gttacttggc
    34861 cactataatc taaaagattg agcatagcct tcatcaaggt tgattttcct gcaccatttg
    34921 gcccgataat cccaacgata gctggtcctt tgatttgtag tgagatattg tctaaggctt
    34981 ttacgttacc gttatagcta accgaaagat tttgcgtatc aatcattttt tctccttaat
    35041 acaaacaaag cacaacacca gaagctgctg tgctttattg ttatattatt ttgctaagcc
    35101 ttcagaaatt ttatcaaggt tccatttcat catggcatag tagctgtctc catcttggcc
    35161 ttttttggct acagagtcag taaagatttc tgcatagatc ggaataccac tgtccttaga
    35221 aacagtctcc attggacgtc tgtcaacact tgactcaaca aaaagcgctg atggcttaac
    35281 gtctttcaat ttttcgatca atgatgaaat ttgatccgga gttccttctt cttcagtgtt
    35341 gatttcccag atgtaggctg atgggacacc gtaagctttt gagaagtatt tgaagcagcc
    35401 ttcacttgtg acgattagct ttttattgtc agcaatagca tcaaattttg attttgcttc
    35461 cttatcaagc ttctctagct tctcaacgta agcttttagg ttgttttcat aggtttcctt
    35521 gtttttaggg tctttagcga tcaattgctt tgcaatattt tttgaataga taaccccatt
    35581 ttcaagattc aaccaagcat gagggtcttc cttgcctttt tcactttcac cttctaggta
    35641 aatcacatca ataccatcag atacagcgaa gtagtccttg tccttttcct tcttagcatt
    35701 ttttacaagc tttgtaaacc aagcctgtcc gccgtcttca aggttaatac cgttatagag
    35761 aataagatcg gcattgctgg tcttctcaac gtcttctggc aatggctcat actcatgcgg
    35821 atcttgacca atcggcacaa tgctgtgcaa gtcaatcttg tcacctgcaa tatttttagt
    35881 catgtcagca ataatggaat tggtaaccac aaccttgagc ttgtcactct tagcttcctt
    35941 gtttccacca ttagagcagg caaccagcat gaaaacagcc aaaaaagcac tcaaggcgag
    36001 gctaagtttc tttttcatca gttatctcct taggatctat tatttaatta attaagtata
    36061 gttaattatg ctattagcat aacttttttt taggcctttg tcaagatttt tatgaaataa
    36121 tctgatataa taatcattat aaataagaga aaggctttta gacatgacgc ctaataaaga
    36181 agactatttg aaatgtattt atgaaatcgg agagcaaaac attaaaattt ctaacaaaat
    36241 ggttgcagag agaatgaagg tttctgcacc cgctgtgtca gaaatgatta agaaaatgat
    36301 cgcacaaggc tggattgtaa aggataagac ctgcggctat tatctaacag agcaagggca
    36361 gcgcttagtg gcaaatcttt atcgtaagca ccgattgatg gaggttttct tgatccatca
    36421 actgggctat actgctagag aggtgcacca agaggctgag gtactagagc atactgtgtc
    36481 agatatgttt attgatcgct tggataaaac ccttggctat cctacttttt gccctcatgg
    36541 agggacaatt ccacgccgcc agcagccact aatcgaaatc aacaaaacaa cgcttaatac
    36601 tattaaagag ctgggaattt ttcgtttgag cagggtgcat gatcactttg agcttatcca
    36661 gtacctagaa gcacaccagc tgacgatcaa tagtgagttt agactgattc aaatagatga
    36721 cttcgcaaaa acctatacca tcacttatgc agataaggaa ttgatcattc ctgaaaacat
    36781 cgccaagcag ctctttgtta ctgctattta aataaaaaaa gacctgatat ttgctgtcac
    36841 cacaggctat caggtttttt tggtcatcat tttttatcag gtaaggcctc taaaaaggct
    36901 atcaagacct tggctgattt ttttccagcc tcaacaataa actgatcgaa ggtcatatta
    36961 gcatcgtggg ccgctgtgtc actcatcgcc ctaacaacaa taaatggctt gccagcagct
    37021 tgagctgcct gtgccactgc tgctccctcc atttccactg ctaaggtctc tgggaaatgt
    37081 gctttgatgg tatcaatact gtcttggccg gcaataaagc tatctcctgt tgcaatcagg
    37141 ccaatccgac tattggtctt ttcctgatca agcacctgct taaaggtctc aaccagcttg
    37201 ctatcactgt caaagtaaag gggctgcgca gccatttgac catagtcata gccaaaggcc
    37261 gtcacgtcca catcatgata caccaagcga tcagcaacaa caacatcacc aatagccaag
    37321 ccactagcta ttgctccagc cgatcctgta tttataatag cgtcagcctg aaaatgctct
    37381 gctagcatcg caactgtcat cgctgacatg acctttccaa caccagattg gactaagacg
    37441 agctcatggc gaccaagacg acctgtatag taggtattgg aaagcacctg atgctcttga
    37501 ctatcgtgga gctgctccaa taaaaaccgc agctcctctt ccatagccgc aataattcca
    37561 attttcatat gatatcctta tttgtttttt tctataaatt aaagaccgca taaaccaaga
    37621 gagcaatcaa gacaagcacc gctaagagaa tcagatttaa ccgcgattga aagcgactgc
    37681 gctttgcatt ttcaattctg cgacttttgt aaatacgatc agtatgctta tcctcaaagg
    37741 tcatgatttt ggtttcaaaa tctgcataat cgtcaggctc aaactgttct ccgcgctgag
    37801 ccttttcgat aatgtcatca gtcagcaagg gcttgcccat tacacatcac ctccaaaatg
    37861 aagggcgtaa tattgcaggg caatgatggt tttagcatcg acaagctttc cttgtgccac
    37921 tagatccata cattcttgat agctcagctc aagaagctca atcacctcat ctgcgtcctg
    37981 tggtctagga ttggcaactc tctgcaggtc tgtcgccaag tacagcttaa ttttttcatt
    38041 acaaaaacca atcgctgtat aaaactcgtg aataagacgc aaatcaccag aataggcggt
    38101 ttcttcctcc agctctcgtg ctgctgcttc taatgctgag ttggcctcac cgacctctag
    38161 ttttccagca ggaatttcat aagaaatcgc ttcgatagcc ttacggtact gcttgacaat
    38221 taacagctta cgctctggcg ttacagccaa tatagcgact gcaccgcgat gaaaaatcaa
    38281 ttcgcgctta gcctgaccta ggccgtttgg caattggaca tcatctaccg caactttgaa
    38341 aatgtgacca tcaaaaatct cttgcctttt aatcgttttt tcttcaaaat ccatgtctga
    38401 tctccttgct ttctctccat cattttactt tgcttgattt gggtgatgtg gcagcctctt
    38461 ggcatagccc tccttcacca cctgacggct gcgccctata gccacactgt ctgccggcac
    38521 tgactgggct atcgtagacc ctgcggctgt taaagcattc tccccaacct ctactggagc
    38581 tatcaaagtc gaatgactcc caataaaagc gtgatcgcca atcactgtct ggtatttccg
    38641 ttgaccatca taattaaccg taatgcttcc tgcaccaata ttaacctctg agccaatctc
    38701 ggcattcccc aggtaagtca aatgccctgc cttggtattg gcccctagat gagacccctt
    38761 aacctctaca aagttcccaa tatgaacgct ctcatcgagc tgggagtctg ggcgaatgtg
    38821 cgcatagggc cctactgtca caccatctgc taggactgaa tcctcaatca ctgactggct
    38881 caccactacg ccctcaccaa gcctcgaatc aaggatatag ctcccattgc ttatgacact
    38941 tctgctgcca atcctggtct gtccctttaa ggtcacattg gcttcaatca agacgtccgg
    39001 tgcaatctct acactgcttt caatataggt agctgccgga ttttgcaggg tcaccccatt
    39061 aagcatgtgc tgcctgttga tccgctc
//
LOCUS       DARYYD010000017        38530 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.017, whole genome shotgun sequence.
ACCESSION   DARYYD010000017 DARYYD010000000
VERSION     DARYYD010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38530)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38530)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38530
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.017"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(366..2156)
                     /locus_tag="TV188_000783"
     CDS             complement(366..2156)
                     /locus_tag="TV188_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HEL1534159.1"
                     /translation="MTHLVDLRKKPYSLDEEAICWVEDTIAAMTLEEKIGQLFVNMGA
                     SRSEDYLTQVLEDYHIAAVRYNKGMASEIWDQNYILQTKSKIPMLIAANTEAGGDGAV
                     NDGTKVGDEIKVAATNDPKYAYEMGRIAGLEASAVGCNASFAPIVDLTRNWRNPIIAN
                     RNWGVNVDQIIELSKEYMKGIMEYGIMPFAKHFPGDGIDERDHHLSFASNPMTKEEWL
                     SSFGRIYGELAEAGLPGIMAGHIHLPNVEKAMHPERELDDMLPASLNKTLLDELLRGE
                     LGYNGAIVTDASHMVAMTASMPRRLLLPTAIEAGCDLFLFFNDPDEDLQWMKEGYEAG
                     ILSDERLHDALRRTLGLKAKLGLHRFEGHREDIMLPKDKAMVLINTPEAQAIADEVAD
                     KAITLVKNKQAGIFPVTPERYKRVLIVNVEGYKGGFGAMIAGQKKRASDIVKELLEAR
                     GHEVTVWESTEERIMQLPEEERAAAIANVYAQKQPISNITEHYDLILNLVDVNSGGTV
                     QRIIWPAAKGTPDQPFYVHEVPTIVVSVQHAFALADMPQVGTYINAYDGKDNTMKALV
                     AKLAGESEFTGVSPVDAFCGLIDTQLWHSF"
     gene            complement(2271..3074)
                     /locus_tag="TV188_000784"
     CDS             complement(2271..3074)
                     /locus_tag="TV188_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1534160.1"
                     /translation="MTAKTEQFVFCVDSDGCAMDTMTYKHQLFFGPLAADYFAVADQA
                     SFLKEWDRINLYSRTRGVNRFVGLVMGLEYAGVTGIDALKQWVQHTASLSNQSLEAEL
                     LKRPSDDLQKALDWSNEVNRQIEAYKGEALAFLGALAALKALHQLGQVFVVSSANKEA
                     VQKEWQDQGLMTHVDGLYCQDRGKKEAVIAQLIDEGYVRERMMMIGDSPGDLAAAEQN
                     QITFFPILVGKEASSWQDLSHAAEAFTTGDLTELDVKSLTEAFWRNLDR"
     gene            complement(3338..4177)
                     /locus_tag="TV188_000785"
     CDS             complement(3338..4177)
                     /locus_tag="TV188_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEL1534161.1"
                     /translation="MSRVIEFKDKVVVITGAGGVLCGSMAKAFAKAGAKVALLDLNQE
                     AAQAFVDDIEAEGGIAKAYQANVLSKENLEAVRQAVLADFGPADILVNGAGGNSPKAT
                     TDNEFHDTSLPEDTKTFFDLDEAGISFVFNLNYLGTLLPTQVFAQDMVGRKGANIINI
                     SSMNAFTPLTKIPAYSGAKAAISNFTQWLAVHFSKVGIRCNAIAPGFLVTNQNRSLLF
                     TEDGQPTARAEKILKNTPMGRFGEAEELIGGLFFLADEQSASFVNGVVLPIDGGFAAY
                     SGV"
     gene            complement(4193..5287)
                     /locus_tag="TV188_000786"
     CDS             complement(4193..5287)
                     /locus_tag="TV188_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HEL1534162.1"
                     /translation="MKMSFRWYGKHDPVSLEEIKAIPGMQGIVTAVYDVPVGQAWPLE
                     NILELKRIVEAAGLEISVIESIPVHEDIKQGKPNRDELIENYKTSIINVGKAGIPVVC
                     YNFMPVFDWTRSDLNYPLPDGSTSLAFLKADLADVDPVADDLNLPGWDFSYSKEEMKA
                     IIEHYRHHISEEDLWANLDYFIKAIMPTAEAAGVKMAIHPDDPPYGIFGLPRIITGQK
                     AVERFLDLYDSPNNGITMCVGSYASDPQNDVIAMTEYALKRQRINFMHTRNVTAGDWG
                     FQETAHLSQAGDIDMNAIIKLLVDYDWQGPLRPDHGRRIWGDQTKTPGYGLYDRALGA
                     TYFNGLYEANMRAAGKIPDFGITVKTVGDK"
     gene            complement(5549..6946)
                     /gene="uxaC"
                     /locus_tag="TV188_000787"
     CDS             complement(5549..6946)
                     /gene="uxaC"
                     /locus_tag="TV188_000787"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HEL1534163.1"
                     /translation="MAFNDDNFMLKNEAAKRLYQQIKDQPIFDYHCHLDPKEIFEDKV
                     YDNIVDLWLGGDHYKWRLMRANGISEEEITGSASKLDKFKAFARTLQRSYGNPVYHWS
                     VMELKNVFGVCELLTEDNAEEIYHRINAYLVEHQISPRKLIADSRVRFIGTTDHPLDD
                     LAWHKRLAADDTFETVVAPTFRPDEAFIEHQRFADFVARLAQATGRTITDFKSFIAAM
                     EERIAYFAENGCKASDISFTEIVFEAAEPEQLDRLMTRVLEGYQPQPLEVKQWQTAVF
                     AELCRLYKHYGFVTQVHFGALRNNHSAIFNKLGADVGVDSLGDQTGLAINMNRLLDHL
                     VQRDSLPKMIWYNLNPSYNIAVANTLANFQANENGIAGYLQFGAGWWFADTKLGMISQ
                     MNALAEQGLLANFVGMLTDSRSFLSYQRHDYFRRILSTYLGEWIEEGEVPEDYQALGK
                     MAQDIAYNNAIQYFN"
     gene            complement(6974..7591)
                     /gene="eda"
                     /locus_tag="TV188_000788"
     CDS             complement(6974..7591)
                     /gene="eda"
                     /locus_tag="TV188_000788"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015017171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1534164.1"
                     /translation="MLNRLKENYFFAIIRGKTVEDAIAIAKHAILGGIRNIEITYSTP
                     NASEVIRILSAEFEHDDAVIIGAGTVMTPDLAREAIAAGASFLVSPHFSREIAEVANQ
                     ASNLYFPGCATATEIVTAMNASCPIIKVFPGGVVGPGFIKDIHGPIPEVDLMPSGGVS
                     IDNVKEWKNAGAVAVGIGSALASRVEAEGYDSVTRIAASFVSALD"
     gene            complement(7774..8445)
                     /locus_tag="TV188_000789"
     CDS             complement(7774..8445)
                     /locus_tag="TV188_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HEL1534165.1"
                     /translation="MARPLVEKTAERLLKLILERGYEVGAKLPNEYELAQDLEVGRST
                     IREAVRSLATRNVLEVRQGSGTYISSKKGVSEDPLGFSLVKDTAKLTADLFELRLLLE
                     PRIAALTAQHATPKEVEALEKLVVDIEEAVAAGDPKHLQLDVNFHSLMAKYSGNIAMD
                     SLLPVINQSIHLINANYTNRQMKEDSLQAHRDILNAIKAGDPIAAHDAMLLHIMTVKR
                     TAFLS"
     gene            complement(8487..10277)
                     /gene="uidA"
                     /locus_tag="TV188_000790"
     CDS             complement(8487..10277)
                     /gene="uidA"
                     /locus_tag="TV188_000790"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HEL1534166.1"
                     /translation="MLYPILTKTRKIYDLGGLWQFKLGDHNPQELLASDELMVVPTSF
                     NDVVVDKDKRNYIGDFWYERFVDVPDLAADEELVLRFGSVTHNATVYVNGQALGQHKG
                     GFTPFEVLVPETHYQDNQIKVSVCANNILDYTSLPVGNYSEETQEDGSIKKIVKENFD
                     FFNYAGIHRPVKLMVRPKCHISDITITSDLSEDMTSALVEVSVETSAAVDEVKVTIFD
                     EEHKLVAQAIDGKARLDKVRLWEVLDAYLYTAHVEIIVDGNVVDSYDEPFGIRSIAVE
                     KGQFLLNGKPVYFKGFGKHEDTFINGRGLNEAANLMDMNLLKELGANSFRTSHYPYSE
                     EMMRLADRMGILVIDEVPAVGLFQNFTASLDLSPKDNGTWSVMKTKEAHEQAIRELVK
                     RDKNHPSVVMWVVANEPASHEEGAHEYFEPLIALYKALDPQQRPVTLVNLLLATPDRD
                     KVMDLVDVISLNRYYAWYVDHGDLIKGEVGLRQELLEWQKKFPNKPILMTEYGADTLP
                     GLHSMWDIPYTEEFQCRFYEMSHRVFDEIPNLVGEQVWNFADFETNLMIFRIQGNHKG
                     LFSRNRQPKHVVGLFKERWNTIPHYNYKKK"
     gene            complement(10298..11326)
                     /locus_tag="TV188_000791"
     CDS             complement(10298..11326)
                     /locus_tag="TV188_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1534167.1"
                     /translation="MKKVVSLGEILLRLSPPQYQTLKQATSLDCQFGGSELNVISSLA
                     QLGHQVSLISAIPDNDLGQMTKTFLFSRQINQEHIIEKGQRLGLYYYQKGFSLRASRV
                     TYDRCHSAFWESKRADYDLEHVFDEADWFHVSGITPALTSDLYELTYYLMTKARAEGL
                     TISFDLNFRASLWSSFQEARDLLSPLVQLADVCIGIEPLTLKGSGALDLKDQLGLNRP
                     YDDEALLKEVLARLADTYGVKCFAFTQREMDYTNEYLLKAYLYQNGSLYKTQKSGIQV
                     LDRVGTGDAFTAGLIHGLLSYKDEQATLDVAMASFKFKHTIEGDSNIMTQDDIDHLLA
                     KESHEIQR"
     gene            complement(11410..12954)
                     /locus_tag="TV188_000792"
     CDS             complement(11410..12954)
                     /locus_tag="TV188_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1534168.1"
                     /translation="MEKTIDQRVEEVTYNRAKVWQLVLFALNNASTNIYLFTFMFVTY
                     FSTGVLGLAAIFVSQIMGYIRIFDGFIDPAIGILIDKTETKFGKYRPILIIGNIITAL
                     SLILLLGLSGVSENIRFPLFILVLIIHKIGYSMQQTITKAGQTALTNDPKQRPIFNIV
                     DAIMTTLLMTGGQFVVSSFLVPKFGNFTPAFFHVLIYGTIVISAILGLLAVLGIWSKD
                     RKEFFGLGENTQKTALKDYLKVIKGNQPLQVLSIAAALVKFAVQFFGDSVVMVILFGV
                     LFGNYALSGQFSLLFIVPGILINIAFSGIARKRGLRFSYIRALQIGLVGLLAFGIVLF
                     MGNKGDLSLSHINLYTILFTVTLIIARYASQAPASLVLTMGADISDYETSESGRYVSG
                     MIGTIFSLTDSIASSFAPMVIGAVLAGIGFSKTYPTIETPLTPSLKMALIALHVGIPF
                     VALLVALILMSFYKLDKEEMVRIQEKIQVMKASSDKERVQAIAKNVPLSDMDYVDVTK
                     YPVDKD"
     gene            complement(13369..14628)
                     /locus_tag="TV188_000793"
     CDS             complement(13369..14628)
                     /locus_tag="TV188_000793"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1534169.1"
                     /translation="MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDVVTLDGV
                     PAISDVDSLIEIMKLMGAMVTYQGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLL
                     GRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGAQISYEGASMHLMTEAQQLHGAHIYM
                     DTISVGATINTMIAATKAKGKTIIENAAREPEIIDVATLLNNMGAHIRGAGTDVITIE
                     GVERLHGTRHQVIPDRIEAGTYIALAAAVGSGVRITNVLYEHLESFIAKLEEMGVRMT
                     VEEDSIFVEKQEALKAVTIKTSPYPGFATDLQQPLTPLLLRTEGRGSIIDTIYEKRVN
                     HVPELARMGADIAILGSQIVYHGSNRLSGAQVKATDLRAGAALVIAGLMAQGKTEISN
                     IEFILRGYANIIDKLTALGADIQLIED"
     gene            complement(14944..16149)
                     /locus_tag="TV188_000794"
     CDS             complement(14944..16149)
                     /locus_tag="TV188_000794"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEL1534170.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TCVYTGSVHVFGEISTTAYVDINRVVRDTIAEIGYTEAEYGFSAESVGVHPSLVEQSP
                     DIAQGVNEALEAREGQSDDFNAIGAGDQGLMFGFAIDETPELMPLPISLSHQLVRRLA
                     TLRKSGEISYLRPDAKSQVTVEYDEHDKPVRVDTVVISTQHDPEVSNDQIRQDMIEQV
                     IKAVIPAHYLDEKTRFLINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYARHGGGAFSG
                     KDATKVDRSASYAARYIAKNLVAAGLASKAEVQLAYAIGVAQPVSVRVDTFGTSTVSE
                     SILEAAVRQVFDLRPAGIIKMLDLKRPIYRQTAAYGHMGRTDIDLPWEQLDKVSPLTE
                     AVAALSEGA"
     gene            complement(16482..18701)
                     /locus_tag="TV188_000795"
     CDS             complement(16482..18701)
                     /locus_tag="TV188_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1534171.1"
                     /translation="MKSKKLMLMASLFMACHLTLTACQSTKQPTNQPKTKQTAKKATK
                     KKQSKKVKQTRKDRKGVAGIDFPTDDGFILTKDSKILSRTENGIVVEHNGHSHFIFYA
                     DLKGSKFEYLIPKDADLNKPEQTKAASGHHHTSANDPHHHYVFNPADIVAEDALGYIV
                     RHGDHYHYILKSSLGGQVAYPVPNHVPLSAPSSPSGKFAGVDYPTSDGFLFDGTGIVG
                     RTSYGLIVDHNGHNHLVTYESLRNSKWKHLIEQPKEEAPAKPQSDLEKTIALKKAYLA
                     KSLNIPEDSIRVEHTEEGIILDYPHGDHRHATYIDDIDLSKPFDPHAVDPHAKDRIGM
                     ATLRKLGFDEEVISSIIHANAPTEFPSRERDLEKMKAWLATVEYLNIGEIKDPLKRAG
                     LNLMPNIQILGIGFTPITDITPVYQFKNLKQLWMTQTGIKNYDFLKNLPTLEGIDISQ
                     NGVSDLSFLKAFPHYKVISAAGNDITDISILKELPNLESVNLDFNKITDLSALANAQK
                     LVAVSLEHNQIKDLSALSNKGQLTKLFVSNNPDLDLSTLKSSALKEITAKEVNLQSLS
                     FVKDLPALEQLVVDQNKLNSLTGLEHNKSLIQLSANQNMINSLALPGTQSSLQSLNLE
                     ENQLTNFEGVNNYLALEAINVNRNKINTLALKEPNQTLKYIQADGNHFPAEELAAESG
                     QFPQGIIKNFKAAEGGSLNNATPAEAVEDEHKPADTDQEAADKHDHEHHDHDEHHHG"
     gene            19228..20169
                     /locus_tag="TV188_000796"
     CDS             19228..20169
                     /locus_tag="TV188_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEL1534172.1"
                     /translation="MKTSEKIYQLLACSDDYVSGEYLAEQLKLSRTSVWKSIKSLESQ
                     GLHIESLKHKGYRLIQGDILLPELISQELNMPLSYHEKSQSTQLDAKQGIELKHTAPR
                     LYLAPSQYAAKGRLNRQFFASPHGGIYMSLHLKPNVPYADMPPYTMMVASSIVKAISR
                     LTGIDTQIKWVNDIYLGHKKIAGILTEAITSVETGVITDVIIGVGLNFFVTEFSENLK
                     ERAGSLFSNKPSITRNALIIDIWKLFTTIPIKDHIKVYKEKSLVLQKQVSFQENDRQK
                     TATAIDLTDEGHLIVQLDNGQLQVLRSGEISLSSWGD"
     gene            complement(20144..20347)
                     /locus_tag="TV188_000797"
     CDS             complement(20144..20347)
                     /locus_tag="TV188_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 family protein"
                     /protein_id="HEL1534173.1"
                     /translation="MTIRQFMFMAFICAFEAYFFSDLLFSGDYIFALFWGLLLFRDLR
                     RAYAIDQFTKNIINAVNPPRKKD"
     gene            complement(20728..22404)
                     /gene="dnaX"
                     /locus_tag="TV188_000798"
     CDS             complement(20728..22404)
                     /gene="dnaX"
                     /locus_tag="TV188_000798"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEL1534174.1"
                     /translation="MYQALYRKYRSQTFAEMVGQSVISTTLKQAVESEKISHAYLFSG
                     PRGTGKTSAAKIFAKAMNCPNQVKGEPCNHCDICRDITTGSLEDVIEIDAASNNGVDE
                     IRDIRDKSTYAPSRATYKVYIIDEVHMLSTGAFNALLKTLEEPSDNVVFILATTELHK
                     IPATILSRVQRFEFKAIKQPAICEHLAAILDKEGIAYEIEALHLIARRAEGGMRDALS
                     ILDQALSLSFDNRVTLAIAEEITGSISISALDDYVQHLIRQKTSQALANLETIYDSGK
                     SMSRFATDLLTYFRDLLIVKSGGDHHRQSALFDDNLAVSFDQLFTMIATVTKHLPEIK
                     KGTHPRIYAEMMTIQLAEQGQAADTAIPSSLLADVDDLKHEISQLRETISQLQAQKGL
                     TAQATPAHSIKPKAFTYKVDREKILKIMEETVQDSQQSRQYLEALKSAWNEILDSISA
                     QDRALLLGSEPVLANSENAILAFEAAFNAEQAMKRQDLNDMFGNIMSKAAGFSPHILA
                     VPKADFHHIRSEFAMTIKTKKETAKESEQATFDMPEGFDFLTDKIHLIED"
     gene            complement(22404..22901)
                     /locus_tag="TV188_000799"
     CDS             complement(22404..22901)
                     /locus_tag="TV188_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEL1534175.1"
                     /translation="MNKTTKIEHYQLLLAQAKALFSNESNALANLSNASALLKMTLPH
                     SVFAGFYLFDGQELILGPFQGKVSCVHIKLGKGVCGESAQSGQTIIVDDVKKHANYIS
                     CDSAAMSEIVVPMLKAGRLVGVLDLDSSLVADYDQIDQDYLEQFVALLLENTSFRFDM
                     FGVEN"
     gene            23081..23851
                     /locus_tag="TV188_000800"
     CDS             23081..23851
                     /locus_tag="TV188_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEL1534176.1"
                     /translation="MLLVFNGIEYECLNLVSPKQTFYQSAALILSTSLLGIYLIPFSL
                     AIAYLKRIYQIRISTLLLAGLGGLYISGFLASFGNQVLEQFWISLIKPNIALEEWTGA
                     LTGPFVEEPIKAFAAMLVIYLLPAINLKQKLVISLISGMGFQLTEDISYIASAADRSI
                     NDILPTTLARISSSPNSHWVYTGIFTMGAYLLIKKSQLFPRSLQIFWVVSPLALHFIW
                     NSPISDLAGVAVIHGTITTLIFISLFKKIHALDDSIAY"
     gene            complement(24033..24305)
                     /locus_tag="TV188_000801"
     CDS             complement(24033..24305)
                     /locus_tag="TV188_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002998338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEL1534177.1"
                     /translation="MLPSLILLFGWNAVVFAAYGSDKHRAQKGQWRLSEKMLLTLSLL
                     CGGIGAYLAGHYFNHKTKKWYFVLSWYMGILMTLVLCYYLYQWYIL"
     gene            complement(24328..24954)
                     /gene="udk"
                     /locus_tag="TV188_000802"
     CDS             complement(24328..24954)
                     /gene="udk"
                     /locus_tag="TV188_000802"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEL1534178.1"
                     /translation="MLKKPIIIGVTGGSGGGKTSVSRAILNSFPNARIAMIQHDSYYK
                     DQSHISFEERVKTNYDHPLAFDTDFMIQQLKELLAGRPVDIPIYDYKEHTRSNRTFRQ
                     EPQDVIIVEGILVLEDERLRELMDIKLFVDTDDDIRIIRRIQRDMVERGRSLESIIEQ
                     YTSVVKPMYHQFIEPSKRYADIVIPEGVSNVVAIDLINTKIASILGEL"
     gene            25050..26144
                     /locus_tag="TV188_000803"
     CDS             25050..26144
                     /locus_tag="TV188_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1534179.1"
                     /translation="MITNLPTQWQEKLAKLGFTNLTPIQEQVFQPIVDGKSLLGISPT
                     GTGKTLAYLWPSLLRLSPKKAQQLLILAPNTELAGQLFEVTKEWAEPLGLTAQLFISG
                     SSQKRQIERLKKGPEIIIGTPGRIFELVRLKKIKMMAINTIILDEYDDLLSDSQYQFV
                     QKLSHYAPRDHQMIYMSATNKIEQASLADHTLVIDLSKQALPCIEHCYMLVDKRHRTD
                     ILRKLANIPDFRGLVFFNSLSDLGATEERLQYSGASVASLASDVNVKQRKAILEAFKE
                     QSISLLLATDIVARGIDIDQLEYVINAEVPRNKEQYTHRAGRTGRMGRSGIVITLVSH
                     PEDIKRLKKFTKVTEMYLKHQQLYQKEIRG"
     gene            complement(26409..27695)
                     /locus_tag="TV188_000804"
     CDS             complement(26409..27695)
                     /locus_tag="TV188_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEL1534180.1"
                     /translation="MKKLNYILIILLSLLLVGVAFTFIRSWKIGQDTQRVIKLEQTAS
                     KDSPKIKKVKYLKKGKQDWYYLSPIEKADDFYVSNLPMSLYQGKQTDKAVIMVKPKLE
                     ASHIKQVNQLVIYKTVYKPQLFGLKKTTEKAVSRYHVKEDYSPFKLEELVAGRLDRIE
                     EEVGKLYPGKEIKLSTDTMIEKNQVLSDGFAIDSGNLILFGHMSIPLASLFDVINPDF
                     LEGSDKTAYEEYLEEKKAKEAEKEGQKLVALTFDDGPDPVTTPQVLDILAKYQAKGTF
                     FMMGSKVVGHEALVKKVSAAGHDVENHSWDHPDLTTLTVDQIQTQINTTNQAIEKACG
                     KRPVYLRPPYGATNDIVRRASGLKEMLWTVDTRDWENRNTAAIMANVKQQLQPGGVVL
                     MHDIHQTSVDALPSIMEYLKAEGYKCVTLSELYGSR"
     gene            28117..29280
                     /locus_tag="TV188_000805"
     CDS             28117..29280
                     /locus_tag="TV188_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1534181.1"
                     /translation="MSQKLGKQLIRSVVTALAAIAFGIFPASETTNHITYAEVNSLTP
                     SVEWPLEQYPNYYSIEGKSNINTKDFPKLYTTTEKVYKKSGRSTKRVTVSDLQYAALD
                     GYGRSGAAYGIITKDMIAMSAGYREKWESNPEPSGWYTYHFKETGKLATEADYLHSKS
                     KIKRTSNNSYESIVLSNGKIRNGYLFDRSHLIADSLGGRPFRNNLITGTRTQNVGNND
                     RKGGMQYIENKVLNYINHNPQVHVYYKAVPIYSGSELLPRAVVVSALSSDGKIDETVR
                     VFNTVNGFTINYQYSGISHDKGMEASSESEAEDITDESTPVAEPADEEAMETEAAAND
                     TIVYVTSNGQSKVYWYNKDHLPEKVNLNKVVEMTEQEALNRGKHHSSLEKINQ"
     gene            complement(29403..32021)
                     /gene="alaS"
                     /locus_tag="TV188_000806"
     CDS             complement(29403..32021)
                     /gene="alaS"
                     /locus_tag="TV188_000806"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEL1534182.1"
                     /translation="MKQLTSAQIRQMWLDFWKSKGHSIEPSANLVPVNDPTLLWINSG
                     VATLKKYFDGSVIPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAIEWGFELLTSPEWFDFPKEKLYMTYYPDDKDSYNRWIALGVEPSHLIPLEENFWEI
                     GAGPSGPDTEIFFDRGEAYDPDHIGIRLLEEDIENDRYIEIWNIVLSQFNADPTIPRS
                     EYKELPNKNIDTGAGLERLVAVMQGAKTNFETDLFMPIIKEVEKLSGHTYDQDGDNMS
                     FKVIADHIRALSFAIGDGALPGNEGRGYVLRRLLRRAVMHGRRLGIHETFLYKLVATV
                     GHIMESYYPEILEKRDFIEKIIKREEETFARTIDAGSGHLDQLLAQLKEKGQDRLDGK
                     DIFKLYDTYGFPVELTEELAEDAGYKIDHEGFKAAMKEQQDRARAAAVKGGSMGMQNE
                     TLAGITEPSEFLYETETVASRLSVIIVDNERSEMVSEGQALLVFDQTPFYAEMGGQVA
                     DHGVIKNDKGDLVARVIDVQKAPNGQPLHTVEVLASLALDTVYTLAIDHKRRYAVEKN
                     HTATHLLHAALHKVIGEHATQAGSLNEEAFLRFDFTHFEAVTAQELRRIEEEVNEQIW
                     KALAITTTETDIETAKAMGAMALFGEKYGKTVRVVQIGDYSVELCGGTHLSNSSEIGL
                     FKIIKEEGIGSGTRRIIAVTGQQAFESFRKQEDILKEIAHTLKVPQIEQLPSKVVSLS
                     EQLRDLQKEMAELKEKAAAAQAGDVFKKVQEANGLRYIASEVSVSDAGVLRTFADNWK
                     QRDYSDVLVLAASIGEKVNVLVASKDKRAHAGNLIKALAPIVSGRGGGKPDMAMAGGS
                     DASKLSELLAAVPEHL"
     gene            complement(32377..33378)
                     /gene="prsA"
                     /locus_tag="TV188_000807"
     CDS             complement(32377..33378)
                     /gene="prsA"
                     /locus_tag="TV188_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEL1534183.1"
                     /translation="MKKSTKLLAGIVTLASAMTLAACQSTNDNTSVITMKGDTISVSD
                     FYNETKNTEISQRAMLNLVVSRVFEDQYGKKVSKKRTEEAYNKSAEQYGASFSAALAQ
                     SGLTTDTYKRQIRSAMLVEYAVKEAAKKELTDADYKKAYESYTPEMTTQVTTLDNEET
                     AKAVLGEVKAEGADFAAIAKEKTTAADKKVDYKFDSGDTKLPADVIKAASGLKEGDIS
                     EVVSVLDPATYQNKFYIVKVTKKAEKASDWKKYKKRLKEIVLAEKTQNIDFQNKVIAK
                     ALDKANVKIKDQAFANILAQYANTDKKASKANTSKSDQKSSSDSSKDSQSSKSKSEK"
     gene            complement(33441..34148)
                     /locus_tag="TV188_000808"
     CDS             complement(33441..34148)
                     /locus_tag="TV188_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEL1534184.1"
                     /translation="MVKSYSKNANHNMRRSIVKEDIVHYMRTQLKQNEGFLAELEAFA
                     RQENIPIIQHEVVAYFRLLLQSLQPKRILEIGTAIGFSALLMAENAPEAEIITIDRNA
                     EMIGFAKENFAKYDSRKQITLLEGDAADLLAGLTGEFDFVFMDSAKSKYIQFLPEVLK
                     HLKIGGMVVLDDVFQGGDIAKPIKEVRRGQRTIYRGLQDLFAATLDNPGLTASLLPLS
                     DGLLMIRKNQADIRLLD"
     gene            complement(34231..34869)
                     /locus_tag="TV188_000809"
     CDS             complement(34231..34869)
                     /locus_tag="TV188_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1534185.1"
                     /translation="MKTSLIFDMDGVIVDSEYIFLSTKTQMLLDRGIDTNEAYQYQFM
                     GTTFDDMWTTMKKECQLEDSVEALIAEMNHRRQAMLERDGVKAIAGAAQLIKHLHAKG
                     YRLAVASSSPKADIIRNLTALGLLDCFEVLVSGEEVARSKPAPDIFLKAAEWLSVDPK
                     TCLVIEDSKHGSQAAKAAQMTCIGFANPDYPLQDLSACDSIVKQLKAVCELL"
     gene            complement(34919..35551)
                     /locus_tag="TV188_000810"
     CDS             complement(34919..35551)
                     /locus_tag="TV188_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEL1534186.1"
                     /translation="MTVNLIWDFDGTLVQSSEAIRQALGLLYQTYQLPFDEAWVMDTI
                     IQESIGQLLKRLAEAHQLDFSELLAFFTREQEARDHLIALMPTAKETLALTSQQGVKP
                     FIVTHKGRTTQAVLQRLGIADYFTEVITADCGFKRKPDPEALLFLIHHYQMDKSQTYY
                     IGDRPLDLAAARAAGISSINLLLPDSDDNHHISQLSDIVELFSGKNSSSN"
     gene            complement(35541..36098)
                     /locus_tag="TV188_000811"
     CDS             complement(35541..36098)
                     /locus_tag="TV188_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1534187.1"
                     /translation="MKEIRTIALADQAAFKRFQDILLAEKASGNTFVETKKVEDFAAF
                     VEQSRRFEVQTDHPDWSTSTNYYYFLDGQLVARIGCRWQLEKGDLATIGGHIGYVTRT
                     DYRGRGIMTDLLAFALQQYQERGIKRVLITANKDNIASRKTIEKAGGILEDIVQVADD
                     YPTTSLAGQAIARYWIDLRGKDCDS"
     gene            complement(36297..38099)
                     /gene="pepF"
                     /locus_tag="TV188_000812"
     CDS             complement(36297..38099)
                     /gene="pepF"
                     /locus_tag="TV188_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1534188.1"
                     /translation="MTDNRSHLEEKYTWDLSTIFATDAAWETEADSLLAAIEAARQQA
                     GHLLDSSSSLLDITELHLELARRVEKVYVYASMKNDQDTTVAKYQEYQAKASGIYAKF
                     SEAFSFYEPEFMALSQEAYQAFLAETPELTVYDHFFDKLFKTREHVLSQAEEELLAGA
                     QEIFNGAEETFSILDNADIAFPIVTNDKGEEVELTHGNFISLMESKDRKVRRAAYEAM
                     YSTYEQFQHTYAKTLQTNVKVQNYKARVHKYASARQAAMSANFIPEAVYDTLLENVNK
                     HLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALEKAEKVLAVFGQDYS
                     ERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSL
                     HSTFTRETQPYVYGDYSIFLAEIASTTNENIMTEALLHEVQDDKERFAILNHYLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSEYLNNLYADLNEKYYGLKKEDNHFIQYEWA
                     RIPHFYYNYYVYQYATGFAAASYLADKIVHGTQEDIDHYLTYLKSGNSDYPLEVIAKA
                     GVDMAKGDYLEAAFRVFEERLTELEDLVARGAHL"
     gene            complement(38089..>38530)
                     /locus_tag="TV188_000813"
     CDS             complement(38089..>38530)
                     /locus_tag="TV188_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1534189.1"
                     /translation="IHEDLFGKVSYLVKTCSLDDDLLAFLRLPYQRKGLSAYQLQMDK
                     HLLRRIQKALLAKDSKWLKKQEEAYLAGDNLLDRPLEAYYPQVKPIACSAGFCQIHED
                     LSHYYDCFEKYYAKAANKEVQKLFSPAYYVKMISNRNLGGPYDR"
BASE COUNT        11245 a         9109 c         7293 g        10883 t
ORIGIN      
        1 ttttgttata aatcattaat atattatatt ttttcataat ttaaaattat tcttaatata
       61 tcatctctaa aaaacattat ctgttcaatt gtttcactta tcaacaagct tatagcttgt
      121 ctatcatctg aagcaaggtt gagcattagg cacaaaaaga aaagctagaa tgaccctcta
      181 gcttttcttt aggattaaca ggctctatca tctccatatc ggataaaact ccccaccaca
      241 gggattatgg ggctatttct gcagctacaa ggggctgatt aacaggtttt atcctgaaat
      301 ctttttaaat cattcagagc aatcaccgca gaacacgtaa agcctctact tatcctgtag
      361 caacctcaga agctatgcca tagctgggta tcaatcaagc cacaaaaggc atcaacagga
      421 gacactccag tgaattcaga ttcaccagct aattttgcaa ccaaagcctt catagtgttg
      481 tccttgccat cgtaggcatt aatataagta ccaacctgtg gcatatcagc aagggcaaag
      541 gcatgctgaa ctgaaacaac gattgttggg acctcatgga cgtagaatgg ctgatccggt
      601 gttcccttag cagctggcca gataatacgc tgaactgtac ctccagaatt gacgtccacc
      661 aaattaagaa ttaaatcata atgctctgta atgtttgaaa tcggctgctt ttgtgcataa
      721 acattagcaa tagccgctgc acgctcttcc tctggtagct gcatgattcg ctcttcggtt
      781 gattcccaga cagttacctc atgcccacgc gcctctagca attccttgac aatgtctgag
      841 gcccgtttct tctgtcctgc aatcatagca ccaaagccac ccttatagcc ctccacgtta
      901 acaatcagca cacgcttgta gcgctctgga gttaccggga aaatccctgc ctgcttgttt
      961 ttcacaaggg taatggcctt gtcggcaacc tcatctgcaa ttgcttgagc ctctggtgtg
     1021 ttaatcaaga ccatcgcctt gtccttaggc agcataatat cttctcggtg tccttcaaag
     1081 cgatgaagtc caagctttgc tttcaagcca agcgtacgac gaagggcgtc atgaaggcgt
     1141 tcgtcactta aaattcctgc ctcatagccc tctttcatcc attgtaggtc ttcatctggg
     1201 tcattaaaga ataaaaagag atcgcagcct gcctcaatcg ctgttggtaa caataagcga
     1261 cgtggcattg aggctgtcat cgcaaccata tgcgaagcgt cagtcacaat agcaccatta
     1321 tagccaagct caccacgcag cagctcatct aagagggttt tattaagtga ggctggaagc
     1381 atatcatcta gctcacgctc agggtgcatg gccttttcaa catttggcag gtgaatatgt
     1441 cctgccataa taccaggtaa gccagcctct gcaagctcgc cataaatacg tccaaagcta
     1501 gatagccact cctccttggt cattgggttt gaggcaaagg acaaatgatg gtcacgctca
     1561 tcaataccat caccagggaa gtgcttggca aagggcatga taccatattc cataatcccc
     1621 ttcatatact ctttggaaag ctcaatgatt tgatcaacat ttacccccca gttgcgatta
     1681 gcaatgattg gattacgcca attacgcgtc aaatcaacaa ttggcgcaaa ggaggcatta
     1741 cagccaacag ctgacgcttc cagtcctgca atccgtccca tttcataagc gtatttagga
     1801 tcgtttgtcg cagctacctt gatttcatca ccaaccttag tgccatcatt gacagcacca
     1861 tcaccaccag cctctgtatt ggcagcaatg agcattggaa tcttggattt ggtttgtaaa
     1921 atataatttt gatcccaaat ttctgaagcc atgcctttat tgtagcgaac agctgcaata
     1981 tgataatcct caagcacctg agttaaataa tcctctgatc gactagcccc catattaaca
     2041 aatagctgac ctatcttctc ctccaaggtc attgctgcaa tggtatcctc cacccagcaa
     2101 atagcttctt cgtctaggct atatggtttt tttcttaaat ctactaaatg tgtcattgta
     2161 cttcctttca actaaagcct tctctgcttg cttttctgtt ttaatgaatg gcgctacagc
     2221 aacctgctac caagccctaa caggctcagc tccactggtc agctacctgc ctacctatca
     2281 agattacgcc agaaggcttc tgtaaggctc ttgacatcaa gctctgtcaa gtcaccagtt
     2341 gtaaaagctt cagcagcatg tgacagatcc tgccacgagc tagcctcctt accaacgagg
     2401 attggaaaaa aagtgatctg gttttgctca gcagctgcta gatcacctgg tgaatctcct
     2461 atcatcatca tgcgctctct cacatatcct tcatcaatga gctgtgctat gacagcctct
     2521 tttttgccac gatcctgaca atacaagcca tcaacatgtg tcatcaggcc ttgatcctgc
     2581 cattcctttt gaacggcctc tttattagct gagctgacaa caaaaacctg gccaagctgg
     2641 tgcaaggcct taagagcagc taaagctcct agaaatgcca atgcctctcc tttgtaggcc
     2701 tcaatctgac ggtttacctc atttgaccag tccaaggcct tttgcaggtc atcactagga
     2761 cgcttaagaa gctccgcctc cagagactga ttggataatg aggcagtgtg ttgtacccat
     2821 tgctttaaag cgtcaatccc tgtaactcct gcgtattcta gccccataac aagcccaaca
     2881 aagcggttaa caccgcgtgt acgcgaataa agattaatgc gatcccactc ttttaagaaa
     2941 gacgcttggt ctgctaccgc aaaataatcc gccgcaagcg gaccaaaaaa gagctgatgc
     3001 ttataagtca tggtgtccat tgcgcagcca tctgagtcca cacaaaagac aaattgttca
     3061 gttttagctg tcattccaac ctccaaatca tctgatgaat taattctaac acagtaagaa
     3121 aacgctgtca atcataaatc ctaatcaagc agcgtttcat ttttaaaagc tatcattact
     3181 tgttgattgc taaaaaaggc tagagtgata aggaacaata gaagccacaa atcatcatac
     3241 ctttattaat ggcagcttgg ctacaaagca agctgtcacg atagaaaaac cacttgaggc
     3301 attgcagttt gagttctcaa gtggtttatt ttttagctta gacgcctgaa taagctgcaa
     3361 atccgccatc aattggcaga acaacgccgt tcacaaagga agcagactgc tcatcagcca
     3421 agaaaaagag gcctccaatt aattcttctg cctcaccaaa gcgtcccatt ggtgtattct
     3481 taaggatttt ttcagcacga gccgttggct gtccgtcctc tgtgaaaagg aggctacggt
     3541 tttgattggt taccaaaaat ccaggagcaa tggcattaca acgaatgcca accttagaaa
     3601 aatgaacagc caaccactgg gtaaagttgg aaatggctgc cttagcccca gaataggctg
     3661 ggatctttgt taatggcgta aaggcattca ttgaagaaat gttaataata tttgccccct
     3721 tacgaccaac catatcctga gcaaagactt gcgtcggcaa caaggtgcct aaatagttta
     3781 aattaaagac aaagctgata cctgcttcat caaggtcaaa gaaggttttt gtatcctctg
     3841 gcaggcttgt gtcgtgaaac tcattatcgg ttgttgcctt agggctgttt ccgccagcgc
     3901 cattcactaa aatatctgct ggaccaaaat ctgctaaaac tgcctgacga acggcctcta
     3961 ggttttcttt agacaataca tttgcctgat aggcctttgc aataccaccc tctgcctcaa
     4021 tatcatcaac aaaggcctgt gccgcctctt ggttaaggtc taacagtgcc accttagccc
     4081 ctgcttttgc aaatgccttt gccatactgc cacaaaggac accgccagct cctgtgatca
     4141 caacaacctt gtccttaaat tcaataactc gactcatctc atgccccttt ttctatttat
     4201 ctccaactgt ttttacagta atgccaaaat ctggtatctt tccagctgca cgcatattag
     4261 cctcataaag cccattaaaa taggtcgcac caagtgcccg gtcatacagc ccatagccag
     4321 gggttttggt ttgatctccc cagatacgac gaccatgatc tggacgaagt ggtccttgcc
     4381 agtcataatc aaccaataat ttgataatag cattcatatc aatgtcacca gcctgtgaca
     4441 agtgagcggt ttcttggaag ccccaatcac cagcagtgac attacgcgta tgcataaagt
     4501 taatacgctg gcgcttaagc gcgtactccg tcatagcgat cacatcattt tgaggatcag
     4561 aagcatagga gcccacacac atggtaatcc cattattagg ggaatcataa aggtctaaga
     4621 agcgctctac agccttttga cctgttatga tacgtggtaa gccaaaaata ccataaggag
     4681 gatcatcagg gtggatagcc atcttaacgc cagctgcctc tgctgttggc ataatagcct
     4741 taataaaata atctaaatta gcccacaggt cttcttcgga aatatgatga cgataatgct
     4801 caataatagc cttcatctct tcttttgagt aagaaaaatc ccaacccggt aggttcaaat
     4861 catctgccac aggatccaca tctgccaagt ctgcctttaa aaaagcaagt gaggttgatc
     4921 catcaggcaa tgggtaatta agatctgagc gagtccaatc aaacactggc ataaaattat
     4981 agcaaaccac aggaatacct gccttaccaa cattgatgat agaggtctta taattttcaa
     5041 tcagctcatc acgattgggc tttccttgct tgatgtcctc gtgaacagga attgattcga
     5101 tgactgaaat ctcaaggcct gcagcctcaa ctatcctctt caattcaagg atattttcta
     5161 gtggccaagc ctgaccaact ggtacatcat acacagctgt tacaattccc tgcataccag
     5221 gaatggcctt gatttcctct aaacttactg gatcatgctt tccataccag cgaaacgaca
     5281 ttttcatagt atcatacctc gagttctcgt aaactccttt tcctttcgat tcacacaatt
     5341 gttatttatt attgtttttg gggctaatac ccttgcaact aaagggcctg ggcctgctac
     5401 ttggtctagc ctttgtaatc tagtcaatca acaagacgcc gacagcagct agcaggccga
     5461 tattgtccta gcctctttta agactaggac cttaatcata gagcaacatc atatttctat
     5521 gcttcttcta gttaacgacc aaggcagcct agttaaaata ctggatagca ttattgtagg
     5581 caatgtcctg agccatttta ccaagtgcct gataatcctc tggtacctca ccttcttcaa
     5641 tccactcacc aaggtaggtc gacaaaatac gtctgaaata atcatgacgc tgataggata
     5701 aaaatgaacg tgaatccgtt agcatgccga caaaattagc taacaaacct tgctcagcca
     5761 aggcattcat ctggctaatc ataccaagct tggtatcagc aaaccaccag cctgcaccga
     5821 attgcagata gcccgcaata ccgttttcat tggcttggaa attagctagt gtattagcaa
     5881 ccgcgatatt atagctcgga tttaggttat accaaatcat ctttggcagg ctgtctcttt
     5941 gcaccagatg atccagcagg cgattcatat tgattgctag tcctgtttgg tctcccagtg
     6001 agtcaacacc cacatctgcc cccagcttgt tgaatatagc tgaatgatta ttgcgaagag
     6061 caccaaaatg cacctgagta acaaagccat agtgcttata aagcctgcaa agctctgcaa
     6121 acaccgctgt ctgccattgc ttgacctcta acggctgcgg ctgatagccc tctaaaaccc
     6181 ttgtcatgag acggtctaat tgctctggct ctgctgcttc aaagacaatc tctgtaaagc
     6241 tgatgtcact ggccttacaa ccattttctg caaaataggc aatacgctct tccatagccg
     6301 ctataaagct cttaaaatct gtaatagttc ttccggtagc ttgagcaaga cgagccacaa
     6361 aatctgcaaa gcgctgatgc tcaataaaag cctcatctgg tctaaaggtt ggcgcgacaa
     6421 ccgtctcaaa ggtatcatca gcagctaacc tcttatgcca agctaggtca tcaagcgggt
     6481 gatctgtcgt accaataaac cgcactcggc tatctgcaat caactttcta ggactaatct
     6541 ggtgctcaac caagtaagca ttgatacgat gatagatttc ctctgcatta tcctcagtca
     6601 gtagctcaca gacaccaaag acatttttca actccatcac tgaccagtgg taaacaggat
     6661 tgccatagga gcgctgaagt gtacgggcaa aggccttgaa tttatccagc ttagaggctg
     6721 agcctgtgat ttcttcttcc gaaatgccat tagcgcgcat caagcgccac ttgtaatgat
     6781 caccaccaag ccaaaggtca acaatattgt cataaacctt gtcctcaaaa atttcctttg
     6841 gatctaagtg acaatggtaa tcaaaaatag gctgatcctt gatttgttga tagaggcgct
     6901 ttgctgcctc attttttagc ataaaattgt cgtcattaaa agccatctcg tcctcctctt
     6961 atgaccaatt cccttaatca agggctgata caaatgacgc tgcaatacgg gttacactat
     7021 catagccctc agcctcaact cggctagcta aggctgaacc aatcccaaca gcaacagcac
     7081 ctgcattttt ccactccttg acattgtcaa tcgacacacc acctgatggc atcaaatcaa
     7141 cctcaggaat aggaccatga atatccttaa taaagcctgg tcctacaaca cctccaggaa
     7201 agaccttaat aatcggacaa gaggcattca ttgctgtgac aatttcagta gctgttgcac
     7261 agcctgggaa ataaagattt gatgcctgat tggcaacctc tgctatttct ctagaaaaat
     7321 gaggactaac taaaaagcta gcacctgctg caatagcttc tcttgccaga tcaggcgtca
     7381 tcactgtccc agctccaata atcacagcat catcatgctc aaactcagct gacaatattc
     7441 taataacctc tgaagcattt ggagtagaat aggtaatctc gatattacga ataccgccta
     7501 aaatagcatg cttagcaatg gcaatagcgt cttctactgt ttttccacga ataatagcaa
     7561 aaaaataatt ctcttttaat cggtttagca taggctcctc cttttcatga aaccgttgtc
     7621 ttagttttat tatataaatc atcagatgat ttgtcaagga aaaagcaaaa aaaggacttg
     7681 gttctagtat ctctaaaacc aagccctctt attcgagcca agaagcaaat cactcaaaac
     7741 tcaatagact gtttccggca agcaagctta agcttatgat agaaaagccg ttcgcttaac
     7801 tgtcatgatg tgcaggagca tagcgtcatg tgccgcgatc ggatctcccg ctttaatcgc
     7861 attcagaata tctctgtggg cttgtagaga atcttctttc atctgacgat ttgtgtaatt
     7921 ggcattgatc agatgaatcg actgattgat caccggtagc aagctatcca tagcaatatt
     7981 gccactgtat tttgccatca aggaatggaa attcacatcc agctgcaaat gcttaggatc
     8041 accagcagct acggcctctt caatatcaac aacaagcttc tctaaggctt caacctcctt
     8101 tggcgttgca tgctgtgctg tcaaagcggc aatcctaggc tcaagcaata gccgcaattc
     8161 aaacaaatca gcggtcagct tggctgtgtc cttgactaag gaaaagccta aaggatcctc
     8221 agaaacacct tttttcgagc taatataagt acctgatcct tgtctaacct ctaaaacatt
     8281 tctagttgct aagcttctaa cagcttctct aatagtgctt cttccaacct ctaagtcctg
     8341 tgctaactca tattcattgg ggagctttgc tccaacctca tacccacgtt ctaaaattag
     8401 ctttaacaag cgctctgctg ttttttcgac taaaggccta gccatacaat cccttcttcc
     8461 tacttattgc tagctactat tgtacactat ttctttttat aattgtagtg gggaatggta
     8521 ttccagcgct ctttaaacaa accaacaaca tgcttaggct ggcgatttct agaaaaaagc
     8581 cccttatgat tgccttgaat acggaagatc atcagattag tttcaaaatc agcaaaattc
     8641 catacctgct ctccaactag attaggaatc tcatcaaaaa cgcggtgact catctcatag
     8701 aagcggcact gaaattcctc tgtatatgga atatcccaca tcgaatgaag accaggaagc
     8761 gtatctgcac cgtactctgt catcaggata ggcttgttag gaaacttctt ctgccattct
     8821 aatagctcct gacgcagccc aacctctcct ttgatcaagt ctccatgatc aacataccaa
     8881 gcataataac ggtttaagga gatcacatca accagatcca tcaccttatc tcgatcaggt
     8941 gttgctaata gcagattaac caatgttact ggacgctgct gcggatctag tgccttataa
     9001 agagcaatca gcggctcaaa gtattcgtgt gctccctctt catggctggc aggctcattg
     9061 gccacgaccc acatgacaac agaagggtga tttttgtcac gcttgacgag ctcacgaatt
     9121 gcttgctcat gcgcttcctt agttttcatg acagaccaag tgccattgtc ctttggcgaa
     9181 agatccaagg aggctgtaaa gttttggaag agccctactg ccggaacctc atcaataacc
     9241 aagattccca tacgatctgc cagacgcatc atctcctcag agtaagggta gtgtgaggta
     9301 cgaaatgaat tggcaccaag ctccttgagc agattcatat ccattaaatt agctgcttca
     9361 ttcaatccac gaccgttgat aaaggtatcc tcatgcttac caaagccctt gaaataaaca
     9421 ggcttgccat ttagtaaaaa ttgtcctttt tcaactgcaa tacttctgat accaaatggc
     9481 tcatcataac tatctacaac attgccatct acgatgatct caacgtgggc agtgtataga
     9541 taagcatcta aaacttccca taaacgaacc ttatcaagtc ttgccttgcc atcaatagcc
     9601 tgcgcaacga gcttgtgctc ttcatcaaag atcgtcacct taacctcatc aacagctgct
     9661 gaggtttcaa cagatacctc gactaaggct gatgtcatat cctcagacaa gtcactcgtg
     9721 atcgtgatat ctgagatatg gcattttggc cgcaccataa gcttcactgg acggtgaata
     9781 ccagcatagt tgaagaagtc aaaattctcc ttgacaattt ttttgatact gccatcctct
     9841 tgagtttctt cactataatt gcccactgga aggctggtat aatctaaaat attattggca
     9901 caaacagata ccttaatttg attatcctga taatgggtct caggcaccaa cacctcaaat
     9961 ggagtgaagc ctcccttgtg ttgccctaaa gcttgcccat taacatagac tgttgcattg
    10021 tgcgtgacag agccaaagcg aagtaccagc tcctcatcag cagcaagatc tggcacatca
    10081 acaaagcgct cgtaccaaaa atcaccgatg taattgcgct tgtccttatc cacaaccaca
    10141 tcattaaagg aggtcggcac aaccatcagc tcatcagagg ctaggagctc ctgcgggtta
    10201 tggtctccta gcttaaattg ccagagcccc cctaaatcat aaatctttct tgtttttgtc
    10261 agtattgggt ataacatacg atttctcctt tatcacatta tcgttgaatc tcatgcgatt
    10321 ccttggccag taaatgatca atgtcatctt gtgtcatgat attactatca ccctcaatgg
    10381 tatgcttaaa cttaaagcta gccattgcaa catctaaagt agcctgctcg tctttataac
    10441 ttaataagcc atgaatcagc cctgccgtaa aagcatcgcc cgtccctact cggtccagaa
    10501 cctgaatacc agatttttgg gttttataaa ggctgccatt ttgatacagg taggccttta
    10561 acaggtattc attggtatag tccatctctc tctgggtaaa ggcaaagcat tttaccccat
    10621 aggtatcagc taacctagcc agcacctcct tcaacaaggc ttcatcatca tagggtctat
    10681 tcaagcctaa ttgatccttt aaatcaagcg cgccgcttcc cttaagcgtc agcggctcaa
    10741 tgccaataca aacatcagcc agctgaacaa gaggcgacaa gagatctcta gcctcctgaa
    10801 aggaggacca tagactagcc ctaaaattca aatcaaagga aatagtcaat ccctctgccc
    10861 tagcctttgt catcaaataa taggtcagct cataaagatc actcgttaga gcaggcgtta
    10921 tcccagacac atgaaaccaa tcagcctcat caaaaacatg ctccaaatca tagtcagcac
    10981 gctttgactc ccaaaaggct gaatgacagc ggtcataggt aacccgactt gctcgcaaag
    11041 aaaagccctt ttgataataa taaagcccta aacgctgacc cttttcgata atatgctcct
    11101 gattaatttg acgcgaaaag agaaaggttt ttgtcatttg tcccagatca ttgtctggaa
    11161 tagctgaaat aagagagacc tgatgcccta gctgagcaag gcttgagatg acattaagct
    11221 cagaacctcc aaattgacaa tctaggcttg ttgcctgctt taacgtctgg tattgagggg
    11281 gtgacaatcg caagaggatt tcacccaagg atacaacttt tttcacaaca ttcctcctta
    11341 tactatcaag ctactctatt attttataaa aaagtcagcc actcctcaaa gaaatagctg
    11401 acccagcacc taatccttat caacaggata ttttgtcaca tcaacatagt ccatgtctga
    11461 cagtggtaca tttttagcga tagcctgcac gcgttcctta tcagagcttg ctttcatcac
    11521 ttgaatcttc tcttgaatac gcaccatttc ctctttgtca agcttgtaga atgacatcaa
    11581 aatcaaagcc actagtaagg ctacaaatgg aataccgaca tgcagcgcaa tcaaggccat
    11641 ctttagactt ggggtaagcg gtgtctcaat cgttgggtaa gtctttgaaa aaccaatacc
    11701 agccagcact gcaccaataa ccattggcgc aaatgatgat gcaatcgagt cagtcaagga
    11761 gaagattgta ccaatcattc ctgagacata acggcctgat tctgatgttt cgtagtctga
    11821 aatatcagct cccattgtta gcaccaagct agcaggcgct tgtgaggcat agcgagcaat
    11881 aatcagtgtc acagtaaaca aaatagtgta aaggttaata tgacttaggc tgagatcccc
    11941 tttattaccc ataaagagca caataccaaa ggctaacaag ccaaccaagc caatctgaag
    12001 agctctgata tatgagaaac gcaaacctct cttacgagca atacctgaaa aagcaatatt
    12061 aatcaaaatc cccggaacaa taaacagcaa tgagaattga ccagacaaag catagttacc
    12121 aaataaaaca ccaaacaaga taaccatgac aaccgaatca ccaaagaatt gaacagcaaa
    12181 cttaaccaag gctgcggcaa ttgataggac ctgtagcggc tggttgccct tgataacctt
    12241 caaatagtcc ttcagagctg tcttttgcgt attttcacca agaccaaaga attcctttct
    12301 gtccttgctc caaataccaa gcactgccaa tagacccaaa atagctgaga taacaatcgt
    12361 gccataaatc aacacgtgga agaaggctgg tgtgaagtta ccaaattttg gaaccaagaa
    12421 gcttgacaca acaaactgtc caccagtcat cagcaaggtt gtcataatgg catcaacaat
    12481 gttaaagatt ggacgctgct tcggatcatt agtaagggct gtctgaccag ccttagtgat
    12541 ggtttgctgc atagagtagc cgatcttatg gataatcaaa accagaataa aaagtggaaa
    12601 acgaatgttc tcactaactc cacttagacc aagcagcaga ataagtgata gggctgtgat
    12661 aatatttccg atgattagga tcggacgata cttaccaaac ttagtttctg ttttatcaat
    12721 caagatacca atcgcaggat caataaagcc atcaaaaata cgaatataac ccatgatctg
    12781 gctgacaaaa atagctgcca agcctagaac acctgttgaa aagtaggtca caaacataaa
    12841 tgtgaatagg tagatattgg ttgaagcatt gtttaaagca aataaaacaa gctgccaaac
    12901 cttagcgcgg ttataggtaa cctcttcaac cctttggtca attgttttct ccatcagaga
    12961 aatccccctt ttatcattcg cttattgtgt aagcgtttta tttctacatg cttatcttac
    13021 tattcatctg atgatttgtc aacacaattt aaactttttt cgcctaattt taaaaaataa
    13081 agcttattta ggattttaat cattaaattc atctgataat ttctggtgtc tttaaaaata
    13141 atcatcagac aattactcat tgacatcaaa aaaactgagc cctgtgcaat acagaactaa
    13201 atcctttcac taatatgtcg tgtccaactt ttgggggtca gtacacagga tagacagggg
    13261 gttcttaaaa atcaaaagcc cctaaaacca ctctcatacc aagcagtctt aggagctcta
    13321 agcattcatg tcaggtgata atcattaggc tatgaaagcc ttcagttctt aatcctcaat
    13381 aagctgaata tcagccccta aggctgttag cttatcaata atgttagcat agccacgtaa
    13441 aataaactca atattgctaa tctcggtttt accctgagcc attagacctg caatcaccaa
    13501 agcagcacca gcccgcaaat cagttgcctt aacctgtgcc ccactgaggc gattagagcc
    13561 atgataaaca atttggctgc caagaatggc aatatctgct cccatacgag caagctctgg
    13621 cacatggttg acacgctttt catatatcgt atcaatgata ctaccacgac cctcagtcct
    13681 taaaagcaga ggagtcaaag gctgctgtag gtcagtggca aagcctggat agggagaggt
    13741 tttaatagtg actgctttca aggcttcctg cttttccaca aaaatagaat cctcttcaac
    13801 cgtcattctc acacccattt cctctagctt agcaataaag ctctctaagt gctcgtaaag
    13861 gacattggta atccttaccc cactaccaac agcggctgcc aaggcaatat aggtaccagc
    13921 ctcaatgcga tctgggatca cctgatgtct ggtgccatga agcctttcaa ctccctcaat
    13981 cgtaatcaca tcagtacctg caccacgaat atgcgccccc atgttattta acagtgtcgc
    14041 aacgtcaata atctcaggct ctctagctgc attttcaata atggtcttac cctttgcctt
    14101 tgtcgcagca atcatagtat taatggtagc gcctacactg atagtatcca tgtagatatg
    14161 agcgccatga agctgctgag cctctgtcat caggtgcatg cttgctccct cataagatat
    14221 ctgggccccc attgcttcaa aagccttcag atgaagatca ataggcctag ggcctaagtc
    14281 acagccaccc ggcaagccca caaccgcctg cccaaagcgt cccaatagac tgccataaaa
    14341 atagtaagag gctcttaggc tgttaatttt accataaggc ataggaatat cttgaacccc
    14401 tctggggtca atctccaagg tatccccctg ataggtcacc atagctccca tgagcttcat
    14461 gatttcaata agactgtcaa catcactaat agctggtacc ccatctaaag tgacaacatc
    14521 gtctgccaaa ataatcgcag gaatgagagc tacaacgcta tttttagcgc ctgaaactgc
    14581 cacctctccg gataaggctt ttccaccatt aataataatt tttcgcatac tttcaaaact
    14641 ttctgatact agaattcaac ctttttattt tatcacaaat agcggtctat tacaatcacc
    14701 tcatcaccag ctgctgcaac aggcttaaca acctgcctct tgatcacttt tcataacagg
    14761 tttttgagaa gccagactct tatctggatc tttcttctgc tgcgcaggcc tttttgtctt
    14821 tcatagccgc caagcctgac aagttttgct ggactaaaaa agctcccaac cagcagcaca
    14881 gccgctagct caggagctat tataccttta agtcaatcat caactaaccg gcgctcaatc
    14941 tgcttaagca ccctctgaca gtgctgccac cgcttctgtc aatggagata ccttgtccaa
    15001 ttgttcccaa ggcaggtcaa tgtctgttcg ccccatgtgc ccataggctg ctgtctgcct
    15061 atagattgga cgcttgagat caagcatctt aatgatccct gctgggcgca ggtcaaagac
    15121 ctgacgaaca gccgcttcca aaatactttc tgacactgtt gatgtcccaa aggtatccac
    15181 acgaactgaa actggctgtg caaccccgat agcataggct aattgaacct ctgctttact
    15241 tgcaagccct gctgccacaa ggtttttggc aatataacga gctgcataag aggctgagcg
    15301 gtcaacctta gttgcgtctt taccagagaa ggcaccacca ccatgacgcg catagccacc
    15361 ataggtgtca acaatgatct tacgaccagt caagccagaa tctccctgag gaccaccaat
    15421 aacaaaacgc ccagtcggat tgataaggaa tcttgtcttc tcatctagat aatgggctgg
    15481 aataacagcc ttaatcacct gctcaatcat atcttgacga atctggtcat tgcttacttc
    15541 tggatcatgc tgggttgata taacaactgt atcaacacga acaggcttat catgttcatc
    15601 atattcgacc gtaacctgtg atttagcgtc tggacgcaaa tagctgatct cacctgattt
    15661 tcgcagtgtc gccaaacggc gtacaagctg gtgagataag gaaatcggca gtggcattag
    15721 ttctggtgtc tcatcaattg caaagccaaa cattagcccc tgatccccag caccaatcgc
    15781 attgaaatca tcgctttgtc cttcacgtgc ttcaagtgct tcattaacgc cttgagcaat
    15841 atctggtgac tgctcaacca gagatggatg aacacccact gattctgctg aaaagccata
    15901 ttctgcctca gtatagccaa tctcagcgat ggtatcacga accacacgat taatatccac
    15961 ataggcagtt gttgaaattt ctccaaaaac gtggaccgag cctgtgtaaa cgcaggtctc
    16021 tgcagcaacg tgtgcctctg gatccttggc taaaatagca tctaaaatag catctgaaat
    16081 ttggtctgca atcttatctg gatgcccttc agatactgat tcagacgtga aaagtttacg
    16141 ttctgacata aaaatgtccc cccttaaaaa gaatgatacc caccagcaca catgccagat
    16201 aggattttcc tagcctcact catcaagcca gccgccaata caaaaggact gtatccaagc
    16261 tagcctatga ctaacgctta gcgagttaca aagtaccggc ttttagactg ctatcctcag
    16321 ataacaaagc cgtcttatcg ggacttaata acttatttat tataccactt ttagcgggat
    16381 ttgtaagagc tccatcagct tttttctcaa aataagaaaa ggaataccgc tacaggcgta
    16441 ttcctcctct taatgtcgtg ataatcagcg caagctatcg attaaccatg gtggtgctca
    16501 tcgtgatcat gatgctcatg gtcatgctta tctgctgcct cttgatcagt atcagccggc
    16561 ttatgctcgt cttcaacagc ttctgctggt gtggcattat ttagactacc accctctgct
    16621 gccttgaagt tcttgataat tccttgtggg aattgtccgc tttcagcagc tagctcctca
    16681 gctgggaagt ggttaccatc agcctgaatg tatttcaggg tttggttagg ctccttcaag
    16741 gccaaggtgt taatcttgtt acgattaaca ttaattgctt ctagggcgag ataattgttg
    16801 acaccctcaa aattagtcag ctggttctct tcaaggttaa gagactgtaa tgagctttgt
    16861 gtacctggta aggccaagct attaatcatg ttctggttag ctgatagctg aatcaggctc
    16921 ttattgtgct caagacctgt caagctgtta agcttgtttt ggtcaaccac tagctgctct
    16981 aatgccggta gatccttgac aaagctaagg ctttgtaaat taacctcctt ggcagtgatt
    17041 tccttgagag cagaggattt taaggttgac aaatcaaggt cagggttgtt tgacacaaag
    17101 agtttggtca attgtccctt gtttgacaag gcactcaagt ccttaatctg attgtgctct
    17161 aggctgacag cgactagctt ttgagcattt gccaaggcag aaagatctgt aatcttgtta
    17221 aagtcaaggt taacggactc taggtttggc aattctttca aaatagaaat atctgtgata
    17281 tcatttcctg ctgccgaaat taccttgtaa tgcggaaagg ctttaaggaa gctcaaatca
    17341 gaaacaccat tttgagaaat atcaattcct tcaagcgttg gcaggttctt caagaaatca
    17401 taatttttaa tgccggtctg tgtcatccac aattgtttga ggttcttgaa ctggtagact
    17461 ggggtaatat cagtgattgg ggtaaagcca atacctaaaa tctgtatatt aggcatcagg
    17521 tttaaacctg cccgcttaag aggatcctta atctcaccga tattgaggta ttcaacagtc
    17581 gccaaccatg ccttcatttt ctctaggtct cgctctcttg atggaaactc agttggtgca
    17641 tttgcatgga taatggacga aatcacttcc tcatcaaagc caagctttct cagagttgcc
    17701 ataccgattc tatccttagc atgcggatct actgcatgag gatcaaaagg ttttgataaa
    17761 tcaatatcgt caatataggt tgcatgacga tggtcaccat gtggatagtc aagaatgata
    17821 ccttcttctg tatgctccac acgaatgctg tcctcaggaa tatttaatga cttagccaaa
    17881 tatgcttttt tcaaagcaat cgttttctca agatcacttt gtggcttagc tggtgcttct
    17941 tcctttggct gttcgattaa atgcttccac ttgctgttac gcaagctttc ataagtgact
    18001 aaatgattgt ggccattgtg atcaacaatc aatccatatg atgttcgacc gacaatacct
    18061 gtcccgtcaa acaagaagcc atcacttgtt gggtaatcaa cacctgcaaa ttttccagac
    18121 ggtgatgatg gagctgatag tggcacatgg ttaggcactg gataagctac ctgaccacct
    18181 agtgagcttt ttaggatata gtggtaatga tcaccatgac ggacaatata gcccaaggcg
    18241 tcctcagcta caatatcagc tgggttaaac acatagtgat ggtgcgggtc attagcacta
    18301 gtatggtgat gacctgatgc tgccttggtc tgctcaggct tgtttaggtc agcgtccttt
    18361 ggaatcaggt actcaaactt gctgcccttg agatctgcat aaaaaataaa atgcgaatgc
    18421 ccattatgct caacaacaat accgttttct gttctagata agatttttga atccttggtc
    18481 aagataaaac cgtcatcagt tggaaagtca atccccgcta ctcccttacg gtcttttctt
    18541 gtttgcttaa cctttttaga ctgtttcttt ttggtcgctt ttttagctgt ctgttttgtc
    18601 ttaggctgat ttgttggctg ctttgtcgac tgacaagctg tcagggtcag gtgacaagcc
    18661 ataaacaggc tagccattag cattaatttt ttacttttca tctttcctcc ataaattaac
    18721 tggttaaata agatattaac tagttaaata taccaaaaaa acaaataatt tcaactgttt
    18781 tcttattttt aattcattct cattcaacaa tcatagtagc ttggctaggt tggcagaaaa
    18841 atgagcctct cctactctca tcaaataaac agatagcctt aatgatggct gagataacag
    18901 catacaaagt cgttaaagtc acttgtaaga aaaagaagga catatcttac caccactatc
    18961 ttgctcatca aagccctacg gctttcagac aaaatcttca taacagcgga aaggctgatg
    19021 aagcagctca gacaaaaaga gcaagctcct taacgtcaag gatcagagat cagcacaaaa
    19081 ataacagcag gctacattaa gaactgcaat tccttgaaat agaattgctt ttttacaaaa
    19141 aaatcgtctc cctagactgt tccatcatct cacgtcattt gtattatttg ctcttgaaat
    19201 ccagtcattt tatactatac tagaattatg aagacatctg aaaaaattta ccaattacta
    19261 gcttgcagcg acgactatgt cagtggagaa tacttggcag agcagctcaa gctttctaga
    19321 acctctgtct ggaaatccat caaaagcctt gaaagtcaag gccttcacat tgaatccctc
    19381 aagcataagg gctatcgcct tattcaagga gatatattgc tgccagagct catcagccaa
    19441 gagctcaaca tgcctttatc ttatcatgag aaaagccagt caacacagct agacgccaag
    19501 caaggaatcg agctaaagca tactgctcct aggctctatc tcgctccaag tcagtatgcg
    19561 gccaaggggc ggcttaatcg ccaattcttt gcgtcacctc atggcggcat ttacatgtcc
    19621 ttgcatctca agccaaatgt tccttacgca gacatgcctc cttacaccat gatggtggcc
    19681 tctagtattg ttaaggctat ttcaagattg accggtattg acacccaaat caaatgggtc
    19741 aatgatattt accttggcca taaaaaaatc gccggtatcc tgactgaggc cattacctct
    19801 gtggaaacag gcgtcattac tgatgtgatt attggcgtag ggcttaactt ttttgtaacc
    19861 gaattttctg aaaacctcaa agaacgagca ggctctcttt ttagcaacaa gcctagtatt
    19921 actcgaaatg ccctaatcat tgacatttgg aagctcttta ccacaatacc aatcaaggac
    19981 catattaagg tctacaaaga aaaatcactt gtccttcaaa aacaagtgag cttccaagaa
    20041 aatgatcgtc aaaaaacagc aactgccatt gacctgactg atgaaggaca cctcatcgtt
    20101 caattagaca atggtcagct acaggtctta aggagcggcg aaattagtct ttcttcctgg
    20161 ggggattaac agcattaatg atgtttttgg taaattggtc aatagcataa gcacgcctta
    20221 aatctctaaa gagcaaaaga ccccaaaaca gagcaaaaat ataatcgcct gaaaataata
    20281 aatcgctgaa aaaataagct tcaaaggcac aaatgaatgc cataaacata aattgtcgaa
    20341 tagtcatact actattatac caagaaaact aaatttccac taacgatttt cacgcagctt
    20401 gaagaaaaag gcagttagcc tgcttcaagc ttttttgctg ctctttgata gcctgtaaca
    20461 gtcaaataaa aaagagctca ctctaaaaac gacgccaaaa gccagcttga ttgctaggct
    20521 tgtagtcaat tgtctcaaat cagtgaatca ctaagcctta taagaactca gtcattgggt
    20581 cacaatgaca cctagctcta agcagcaaaa aagagaacca caccggtcct ctctagcttg
    20641 gcttgtcagc tatctattag tgctgacaat gagccctgtc atctccttat tctagacaat
    20701 tgatacacta ccaatcatca gctagcgcta atcctctatg agatgaatct tatcagttaa
    20761 aaagtcaaac ccctcaggca tgtcaaaggt cgcttgctca gactctttgg ctgtctcttt
    20821 tttggttttg atggtcatgg caaactccga gcgaatatgg tggaagtctg cctttggtac
    20881 tgccaagata tgaggagaaa accctgctgc cttactcatg atattcccaa acatatcatt
    20941 caaatcctga cgcttcatgg cctgctcagc gttaaaggcg gcctcaaagg ccaaaatagc
    21001 attttcacta ttggctaaaa caggctccga gcctagtaac aaagctcgat cctgtgcaga
    21061 aatactatct aaaatctcat tccaagcact ttttagcgct tctaaatatt gtcgtgactg
    21121 ctggctatct tgaacagttt cctccatgat tttcaatatc ttttcccgat caaccttgta
    21181 ggtaaaggcc tttggcttga tggaatgagc tggtgtagcc tgcgcagtta gacccttttg
    21241 agcctgtagc tgtgatatcg tctccctcag ctgactaatc tcatgcttca agtcatcaac
    21301 atcagctagc aggctagacg gtatcgcagt gtctgctgct tgtccttgct ctgccagctg
    21361 aatggtcatc atttcagcgt agattctagg atgggttcct tttttgatct caggcaaatg
    21421 cttggttact gtagcaatca ttgtaaaaag ctgatcaaaa gacactgcaa ggttatcatc
    21481 aaaaagagct gactgcctgt gatgatcacc acctgatttc acaatgagca ggtctctaaa
    21541 ataggttagc agatccgttg caaagcgact catgctcttg ccactatcat aaattgtttc
    21601 tagattagct aaggcctgac ttgttttttg cctgatgaga tgctgaacgt agtcgtctaa
    21661 ggccgaaata gaaatagagc ctgtgatttc ttctgcaata gcaagcgtca ctcgattgtc
    21721 aaaggatagg ctcaaggcct gatctaaaat ggatagggca tcacgcatgc caccttctgc
    21781 tcgtcttgca attaaatgaa gcgcctctat ttcataggct atgccctcct tgtccagtat
    21841 cgccgccaaa tgctcacaaa tagctggctg cttaatggct ttaaattcaa atcgctggac
    21901 tctagacaaa atagtagctg gaatcttgtg tagttctgtt gtggctagga taaaaaccac
    21961 attgtcactc ggctcttcaa gggtctttag gagcgcattg aaggcccctg ttgatagcat
    22021 atgcacctca tcaataatat aaaccttgta ggttgcccgg ctaggagcat aggttgactt
    22081 atctcgaata tcgcgaattt catcaacacc attattagag gcagcatcaa tttcaatcac
    22141 gtcctccagg ctgccagttg taatatctcg gcaaatatca caatgattgc agggctctcc
    22201 cttgacctga ttagggcagt tcattgcctt agcaaaaatt ttggctgcgc tggttttacc
    22261 agttcctctt ggacctgaaa agaggtaagc atggcttatc ttttctgact caacagcctg
    22321 ctttaaggtg gtcgaaataa ctgactgccc aaccatttca gcaaaggtct ggctacgata
    22381 cttccggtaa agggcttgat acattaattc tcaactccaa acatgtcaaa acgaaaagat
    22441 gtattttcta gtaataaggc tacaaattgc tctaaatagt cttgatctat ctgatcataa
    22501 tcagcaacaa gactggaatc caaatccaga acaccaacaa gcctgccagc cttaagcatt
    22561 ggcacaacaa tctcgctcat ggctgctgaa tcacaggaaa tgtaattagc atgctttttg
    22621 acatcatcaa cgatgatggt ttgaccagat tgagctgatt ctccacatac tcccttgcca
    22681 agcttgatat gcacacagga aacctttccc tgaaagggac caaggatcaa ttcttgacca
    22741 tcaaaaaggt aaaagcctgc aaaaacagaa tgaggcaggg tcatttttaa gagggcacta
    22801 gcattagaga gattggccaa ggcattgctt tcattagaaa ataaggcttt agcttgagcc
    22861 aataatagct gataatgttc aatttttgtc gtcttattca tggttcttat tataacatat
    22921 ctgctactaa tcgttaaacg atttccacag gaaaagaatt ttaatcagcc tctctagaaa
    22981 agaaagagat tttatgataa aatagtgagt aatattaaaa aaataggaga gtcagatgcc
    23041 gttgttgaga tataaaaaga ttatcgctac gaccttattt atgttattag tgtttaatgg
    23101 tattgagtat gaatgtctaa accttgtcag tcccaaacaa accttttacc aatccgctgc
    23161 cttaatcctc tcaaccagcc tactagggat ctatctgatt cccttttcac tggctattgc
    23221 ttatctcaag cgcatctacc agataaggat ctcaaccctg ctattagctg ggctaggcgg
    23281 tctttatatt agtggctttt tagcctcctt tggcaatcag gttttagagc aattttggat
    23341 tagcctgata aagcccaata ttgccttaga ggagtggacg ggagctttga cagggccttt
    23401 tgtggaagag cctattaagg cctttgcagc tatgcttgtc atttatttgc tgccagctat
    23461 taatcttaag caaaaattag tcatcagtct catttctggc atgggattcc agctgactga
    23521 ggacattagc tatattgcaa gtgcggctga tcggtccata aatgacattt tgcctacaac
    23581 gcttgccagg attagcagct caccaaactc tcattgggtc tatactggta tttttacaat
    23641 gggagcatac cttttaatta aaaaatctca attattccca aggtctctgc agattttctg
    23701 ggtggtaagt cctctagccc tacattttat atggaactct cctatctcag atttagctgg
    23761 tgtcgcagtt attcatggaa caataacaac ccttatcttt atcagtctat tcaaaaaaat
    23821 ccatgcccta gacgacagca tcgcctacta gcgtcatagg acacgagcaa ccaagcccag
    23881 ccgcatttgg gcatgtgatg gctcatatgc atatatagct actcacctct cgcttaagct
    23941 ataggcagct aaatacctat cacaatagca gaaaaaatga ctaccagtct taaaagggct
    24001 agtagtcatt ttaagctaaa aacaagcact tcttacagga tataccactg atacagataa
    24061 tagcaaagca caagggtcat cagtatcccc atataccatg aaaggacaaa ataccatttc
    24121 ttcgttttat ggttaaaata atgcccagct agataggctc caatcccacc acataagagt
    24181 gacaacgtta atagcatttt ctcagaaagt cgccattgac ctttttgggc tctgtgttta
    24241 tcactgccat aggccgcaaa gaccacagca ttccaaccaa aaagcaagat taggcttggt
    24301 agcatttgtc tgtctccaat cacagcacta cagctcacct aagatgctgg caatctttgt
    24361 gttgatgaga tcaatagcaa ccacattgct aaccccttct ggaatgacaa tatcagcata
    24421 gcgcttactt ggctcaataa attgatgata catcggcttg acaacgcttg tgtactgctc
    24481 aataatgctc tcaaggcttc tgccacgctc aaccatatca cgctgaatac gacggataat
    24541 ccgaatgtca tcatctgtat caacaaaaag cttgatatcc atcagctcac gcaaacgctc
    24601 gtcctctaat accagaatcc cctcaacaat aatgacgtcc tgaggctctt ggcgaaaagt
    24661 tctgttgctg cgagtatgct ccttataatc atagattgga atatcaacag gccggccagc
    24721 caagagttcc tttagctgct gaatcatgaa atccgtatca aaggctaacg ggtgatcata
    24781 attagtctta accctttcct caaagctgat atgtgattga tccttgtaat acgaatcatg
    24841 ctgaatcatc gcaattctcg catttggaaa gctatttaaa atggcacgag acacgctagt
    24901 cttaccacca ccagaaccac cagtcacacc aataataatg ggttttttaa gcattgtaaa
    24961 ctccaaatct aaaagtcttt cggtctattt taccaaattt gccactataa tgctataatg
    25021 aagagaaaac aaaataaaag gatagatata tgataaccaa ccttcccact caatggcagg
    25081 aaaagctggc aaagcttggc tttactaatc tcaccccaat ccaagagcag gtctttcagc
    25141 ccattgttga tggcaaaagc ctattaggca ttagccccac cggaacaggc aaaactctgg
    25201 cctatttatg gccaagcctt ctcaggctaa gccctaaaaa agcccagcag ttgctgattt
    25261 tagcacctaa tactgagcta gctggacagc tttttgaggt taccaaggaa tgggcagagc
    25321 ccttaggatt aactgcgcag ctctttattt ccggaagcag ccaaaaacgc cagatcgaac
    25381 gcctcaaaaa aggcccagaa atcattatcg gaacaccggg acgcattttt gaattagtaa
    25441 ggcttaaaaa aatcaaaatg atggccatca ataccatcat tttagatgaa tacgacgacc
    25501 tactgagtga ctcccaatac cagtttgtcc aaaaactctc ccattacgcg cctcgtgacc
    25561 atcaaatgat ctacatgagt gctactaaca agatagagca agccagtcta gcggatcata
    25621 ccttggtcat tgatctgtct aagcaagcat tgccttgcat tgagcactgc tacatgctgg
    25681 ttgacaaaag gcatcggacc gatatcctac gtaagctagc aaatattcct gactttcgtg
    25741 gtctggtctt ttttaacagc ctgtcagacc taggtgctac tgaagaacgc ctgcaatata
    25801 gtggagcttc tgttgcttct ctagccagtg atgtgaatgt caagcagcga aaggccattt
    25861 tagaagcctt taaagagcag agcatttcac tgctgcttgc gacggacata gtcgctcgtg
    25921 ggattgatat tgaccagcta gaatacgtca ttaacgctga ggttccccgt aataaagagc
    25981 aatatactca tagagctggg cgaaccggtc gtatgggacg atcagggatt gtcataactc
    26041 ttgtcagtca ccctgaagac atcaagcgcc ttaaaaaatt taccaaggtc actgagatgt
    26101 acttgaagca tcagcaatta taccaaaaag aaataagagg ctagctcaaa ggatataaac
    26161 ctaaaaagct tgcctccaag tatgatgtaa agcaactaat cactatttct tacccttgct
    26221 actaaaaaaa cgaacgtaaa gtccttctga catgaagtca aaaccttacg ttcgttttat
    26281 attatactga caccactggc tttattagta tagtagatac tggccatgct tagccagact
    26341 agatactttc ttgaagtgag cccgccattt agtcatgctc tagagcctta cttgcttttt
    26401 ctgactgact agcggctacc atatagctca gataaggtca cacatttgta tccttccgct
    26461 tttaggtatt ccataatact tggcaaggca tctacactgg tctggtgaat atcgtgcatt
    26521 agaacaaccc ctccaggctg caattgctgc ttgacatttg ccatgatagc agcagtatta
    26581 cgattttccc aatctctggt atcaactgtc caaagcattt ccttaagacc cgatgccctt
    26641 ctaacaatat cattagtagc tccataagga ggacgaagat agactgggcg ttttccacag
    26701 gccttttcga tggcttgatt ggtcgtattg atctgtgttt ggatctgatc aacggttagg
    26761 gtcgtcaaat cagggtgatc ccaagaatga ttctcaacat catgaccagc agcactaacc
    26821 ttcttaacca aagcctcatg gccaacaacc ttagacccca tcataaaaaa ggtccccttg
    26881 gcctgatatt tggccaaaat atctaaaacc tgcggtgtgg tcacagggtc tggaccatca
    26941 tcaaaggtca gagcgactag cttttgtccc tctttttctg cctcttttgc cttcttttcc
    27001 tccaaatact cttcataagc agtcttgtct gaaccctcta gaaaatctgg attaatcaca
    27061 tcaaacaggc ttgcaagagg tattgacata tgaccaaata aaataagatt acccgaatca
    27121 atggcaaagc catcgcttaa tacctgattt ttttctatca tcgtatcagt gctcagcttg
    27181 atctctttgc ctggataaag cttgccaacc tcttcctcga tgcgatctaa gcgaccagca
    27241 actagctcct ctagcttaaa ggggctataa tcctctttca catggtaacg actaacagcc
    27301 ttttctgtag tcttttttag accaaataac tgaggcttgt agaccgtctt gtagataacc
    27361 aattgattga cctgcttgat atgtgaagcc tcaagcttag gctttaccat gataacagcc
    27421 ttgtcagtct gcttgccttg atacagagac ataggcagat ttgacacata aaaatcgtca
    27481 gccttctcaa tcggagacag gtaataccaa tcctgctttc ctttcttgag atacttgacc
    27541 tttttgatct ttggactatc cttagaagca gtctgttcga gcttaatgac tctctgagta
    27601 tcctgcccta ttttccaaga tctaatgaag gtaaacgcaa caccgaccaa caataaactt
    27661 aataaaataa tgagaatata atttagcttt ttcaatctcg tcctccaatt accctacaat
    27721 tttaacacaa gatagttgga aaataaataa aaaaagttag gtttccttaa cttttttcag
    27781 tccaaaataa gggcaaaaaa gtgttttatg gtgcaggatt tgcctgagtt attttccctt
    27841 tatcacagcc atttgtcact ggataagggg ctagatatta tacctaaagc ttctctttat
    27901 tgctatcatt attctgacat tcttaggcat gctatttccc ttgataggac ttgattgctg
    27961 tttctttagc ttgtaaggat ctcctaaaaa tgagagtatt tttaagccta taatttatat
    28021 attcgaaaaa ttttgacaaa aatgaggaaa aatattgatt tatttagctt tagtgataaa
    28081 atgagggtga aaaattaaat aaaggaggac attgatatgt ctcagaagtt gggaaaacaa
    28141 cttattcgct ctgttgttac tgccttagcc gccatagcat ttggaatatt tcctgcaagc
    28201 gagacgacta atcatatcac ctatgcagag gttaactcct taaccccttc ggtagaatgg
    28261 cctttagagc agtatcctaa ttactatagc atagaaggaa agtctaatat caacaccaag
    28321 gattttccta agctatacac cactaccgaa aaggtttaca aaaaaagtgg tcgaagcact
    28381 aagcgcgtta ctgtttctga tctgcaatac gctgcacttg atggctatgg ccgttcagga
    28441 gctgcctatg gtattatcac aaaggatatg atcgcgatgt cagccggata ccgcgaaaaa
    28501 tgggaaagca atcctgagcc aagcggctgg tatacatatc atttcaaaga aactggcaag
    28561 ctagctactg aggccgacta ccttcacagc aaaagcaaga tcaaacgaac ctcaaacaat
    28621 agctatgaaa gcatcgtcct tagcaacggt aagattcgca acggctatct ttttgatcgt
    28681 agtcatttaa ttgctgacag cttaggtggt cgtcctttta gaaataatct catcacaggt
    28741 acacgtactc aaaacgttgg caacaacgac cgcaaggggg gtatgcagta cattgaaaac
    28801 aaagtcctaa actatattaa ccacaaccct caggttcacg tttattacaa agccgtacca
    28861 atctactcag gctctgaatt actccctagg gccgttgtgg tttcagcgct ctcctctgat
    28921 ggtaaaattg atgaaaccgt aagagtcttt aacactgtca atggctttac catcaattac
    28981 caatatagcg gcatcagcca tgataagggc atggaggctt ctagtgagtc agaagctgag
    29041 gatattacag acgaaagcac tccagtagct gaaccagctg atgaggaggc tatggagaca
    29101 gaggctgctg ctaacgacac aatagtctat gttacaagta atggccaatc aaaggtatac
    29161 tggtataata aggaccatct gccagagaag gtcaatctca ataaggttgt agaaatgacc
    29221 gagcaggaag ccctaaatcg aggaaagcac cattcctcct tagaaaaaat aaatcaatag
    29281 tctcataacg actaacacaa gagctggttg aagcaaccag ctttttttgt gtgatgaagg
    29341 attagacagc tccttagcta aaagataaag aggctgataa agcactcaac ctcttatcgc
    29401 ttttataaat gctctggtac tgcggctaat agctctgata gcttgcttgc atcactacca
    29461 cctgccatcg ccatatctgg cttaccgcca ccacgacccg acacgattgg cgctaaggcc
    29521 ttaatcagat tgccagcgtg agctctttta tccttacttg caacaagaac attgaccttc
    29581 tcaccaatgc ttgcagccag cacaaggaca tctgaataat ctctttgctt ccaattatca
    29641 gcaaaggtac gcaagactcc tgcatctgat acggatacct cactagcaat gtaacgtaga
    29701 ccgtttgctt cctggacctt tttaaagaca tcaccagcct gagctgctgc tgctttttct
    29761 tttagctctg ccatttcttt ttgcaaatcg cggagctgct cgctgaggct cacaacctta
    29821 cttggaagct gttctatttg cggcacctta agcgtatgtg caatttcttt taggatgtct
    29881 tcttgcttgc ggaagctttc aaaggcctgc tgacctgtca ctgctatgat acgacgtgtt
    29941 cctgagccga tcccctcttc cttgataatc ttgaaaagac caatttctga tgagttggac
    30001 aagtgagtcc ctccacaaag ctcaacagaa taatcgccaa tctgaacaac acgaacagtt
    30061 ttgccatatt tttcaccaaa gagggccata gctcccatag cctttgctgt ttcaatatca
    30121 gtttctgtgg ttgtaatagc taatgccttc cagatttgct cattgacctc ttcttcaata
    30181 cgacgcagct cctgggctgt aacggcttca aagtgtgtaa agtcaaagcg taaaaaggct
    30241 tcttcattta aggaacctgc ctgagtggca tgttctccaa taaccttgtg aagggcagca
    30301 tgaagcagat gagtagcggt atggtttttc tcaacagcat agcggcgctt gtgatcaata
    30361 gcaagagtat aaacagtgtc taatgcaagg cttgcaagaa cctcaacagt gtgaagaggc
    30421 tgaccattcg gtgctttttg cacatctatc acacgagcaa caaggtcacc cttatcattt
    30481 ttgataaccc catgatcggc aacctgacca cccatttcag cataaaacgg tgtctgatca
    30541 aacacaagca aggcctgtcc ttctgaaacc atctcactac gctcattatc aacgatgata
    30601 actgataagc gagaggcaac agtctctgtt tcgtacaaaa attctgatgg ctctgtgatg
    30661 cctgccagtg tctcattttg catgcccatt gagccaccct taacagctgc tgcacgggca
    30721 cgatcctgct gctccttcat agctgccttg aagccttcat gatcaatctt atagccagca
    30781 tcttctgcta attcttcggt caattcaact ggaaagccat aggtatcata cagcttaaag
    30841 atatccttgc catcaagcct gtcttgcccc ttttccttta gctgcgccag caattgatcc
    30901 aaatgccctg atcctgcatc aatggtacgt gcaaaggttt cctcctcacg cttgataatt
    30961 ttttcaataa agtcacgctt ctcaagaatc tctggataat aggactccat gatatgacct
    31021 acagtagcta ctagcttata aaggaaggtc tcatgaatac cgagcctacg accatgcata
    31081 acagcacgac gaagcaagcg acgaagcaca tagccacgac cttcattacc aggtagggca
    31141 ccatctccaa tcgcaaatga caaggcacga atgtggtctg caatgacctt aaagctcatg
    31201 ttgtcaccat cttggtcgta agtatggcca gatagctttt ccacttcctt gatgatcggc
    31261 ataaataggt cggtttcaaa gtttgttttt gcgccctgca taacagccac aagacgctct
    31321 aagccagcac ccgtatcaat gtttttgttt ggaagctcct tgtactctga gcgaggaatt
    31381 gtagggtctg cgttaaattg agacaaaaca atattccaaa tttcaatata acggtcgttt
    31441 tcaatgtcct cttccagcaa tctaatccca atatgatcag gatcataagc ctcaccacga
    31501 tcaaagaaaa tctctgtatc aggtcctgac gggcctgcac caatctccca aaaattttcc
    31561 tctaatggaa tcaaatggct tggctcaacg cccagagcaa tccaacgatt gtaagagtcc
    31621 ttgtcatctg ggtagtaggt catgtataat ttttcctttg gaaaatcgaa ccattccgga
    31681 cttgttaaca attcaaagcc ccactcaatc gcttcgtcgc gaaaataatc tccgatagaa
    31741 aaattaccaa gcatttcaaa catagtatgg tgacgagctg tcttaccaac attttcaata
    31801 tcgttagtgc ggattgactt ttgagcgttg gtaatacgag gattttcagg aatgactgac
    31861 ccatcaaaat attttttgag ggtggccaca ccagagttaa tccaaagcag ggttgggtca
    31921 ttgactggca caagattggc cgaaggctca atagagtgac cttttgattt ccaaaaatca
    31981 agccacattt ggcggatttg ggctgatgtt aactgtttca tgattaagat accaagagcg
    32041 attagagaga ctgggtatga ttgtccttag cataagtagc ctggggagac gatctctact
    32101 cgcattcagt tcctttcgtt gattttttat gggattaggc taaaagccat caaaacaaaa
    32161 caagcccata tcacagaggg cgaaaaccgc ggtaccacct ctattcaatg agcttgtcat
    32221 tcttaattac ttatatcaga taaaatcaca ttaagcagca tgcctatcag attatccgta
    32281 actcacagca accgtcactt ctctgggtca aatccttgat aaacaattct taactaaacc
    32341 agtataaagc ttttttgagc attcgtcaat gaaaatctat ttttctgact tagatttaga
    32401 agattgacta tccttgcttg agtctgaaga tgatttctga tctgacttgc ttgtgttcgc
    32461 cttgcttgct tttttatcag tattggcata ctgtgccaag atattagcaa atgcttggtc
    32521 tttgatctta acatttgcct tgtctaaggc ctttgcaatg accttatttt ggaaatcaat
    32581 gttttgtgtc ttttcagcca agacaatttc ttttagacgt ttcttatatt tcttccaatc
    32641 agaagccttt tcggcttttt tggttacctt aacaatatag aacttgtttt gataagtagc
    32701 cggatctaag acagaaacca cctctgaaat atcaccctct tttaatcctg aggcggcctt
    32761 gatcacatct gctggtaact tagtgtctcc tgagtcaaac ttatagtcta ccttcttgtc
    32821 tgctgctgtt gtcttttcct tagcaatagc agcaaagtca gcaccctcag ccttaacctc
    32881 acctaaaaca gcctttgctg tttcttcatt gtctagagta gtgacctgag tagtcatttc
    32941 tggtgtgtat gactcatagg cttttttgta atcagcatct gtcagctctt ttttagctgc
    33001 ttctttaaca gcatattcaa ccagcatggc tgagcgaatt tgacgcttgt aggtatctgt
    33061 tgtcaagcca gactgcgcaa gggctgcaga gaatgacgca ccgtattgct cagctgattt
    33121 attgtaagct tcttccgttc ttttcttaga aaccttttta ccgtattggt cctcaaaaac
    33181 acgactaacc acaaggttta gcattgctct ttgagaaatc tctgtatttt ttgtttcatt
    33241 gtaaaaatca ctaacactga tagtgtcgcc cttcatcgta atgacacttg tattgtcatt
    33301 tgtagactga caggctgcta gggtcattgc tgatgctagg gttacgatac cagcaagtaa
    33361 tttagttgat tttttcatgt gattttgtgc tcctttttgt cattaaccag tatattatat
    33421 cacaatttct taaacgtaac ttaatctaac aaacgaatat ctgcttgatt tttacgaatc
    33481 atcagcaagc catcactaag cggcagcagg ctggctgtca atccaggatt atcaagagtt
    33541 gctgcaaata agtcctgaag gccacgataa atcgtgcgct gtcctctccg aacctccttg
    33601 atcggcttag caatgtcacc cccctgaaac acatcatcta aaacaaccat tccacctatt
    33661 tttaagtgct ttaacacctc tggaagaaac tgaatgtatt ttgattttgc agagtccata
    33721 aaaacaaagt caaactcgcc agtaagtcct gctaaaagat cagccgcatc tccttcaaga
    33781 agggtaattt gcttgcggct atcgtatttt gcaaaatttt ccttggcaaa gccaatcatc
    33841 tcagcattgc gatcaatcgt tataatctct gcctcaggag cattttctgc cattagcaag
    33901 gcagaaaagc caatagctgt gccaatttct aaaatccttt tgggctgcaa gctttgcaat
    33961 aaaagcctga aataagcaac aacctcatgc tggataatgg gaatattttc ttgtctggca
    34021 aaggcctcaa gctctgctaa aaagccttcg ttttgcttta gctgcgttcg catgtagtga
    34081 acaatgtctt ctttgacaat agagcggcgc atattatgat ttgcattttt actatatgat
    34141 ttaaccatgc tatccattat ataaaaaaac tctaggtaat gctagggctt tcactagcct
    34201 attcaccttt gacgatctga gtagtatcta tcaaaggagc tcacagacag ccttaagctg
    34261 cttgacaatg ctatcacaag cagacaagtc ctgtaaggga taatcaggat tggcaaagcc
    34321 gatacaggtc atctgagcag ccttagcagc ctgactacca tgcttactat cctcaatgac
    34381 aaggcaggtc ttgggatcaa cgcttaacca ttcagcagcc ttaagaaaaa tatctggcgc
    34441 tggctttgag cgagcaacct cttcaccact aactaacacc tcaaagcagt ccaaaagacc
    34501 tagtgcagtg agatttctaa taatatctgc cttaggcgat gaggaagcta ctgccaagcg
    34561 atagcccttc gcatgcaggt gcttgattaa ttgagcagca cctgctatgg ccttgacacc
    34621 gtcacgctca agcattgctt gacgacgatg attcatctca gcgatgaggg cttcaacaga
    34681 atcctctagc tgacactcct ttttcatagt tgtccacata tcgtcaaagg tggttcccat
    34741 aaactggtac tgatacgctt cattggtatc tatgcctcgg tccaatagca tttgtgtctt
    34801 ggttgacaaa aagatatatt ctgagtcaac aatcacaccg tccatatcaa aaataaggct
    34861 tgttttcatc atctacctcc tcttatgcta tatctcagtc aggtcaagag caagactatt
    34921 aattactaga gctattttta ccagaaaaaa gctcaacaat atctgacagc tgactaatat
    34981 gatgattatc atcactatct ggcagcaata ggttgataga gctaatccca gctgcccttg
    35041 ctgcagcaag gtctaagggc ctatcaccaa tatagtaggt ctgcgactta tccatctgat
    35101 aatgatgaat gagaaaaaga agcgcttcag ggtccggctt acgcttaaag ccacaatctg
    35161 ctgtaatcac ctctgtaaag taatcagcaa tccccagacg ctgcaaaaca gcctgagtgg
    35221 ttcgtccttt atgagtcaca ataaaaggct taaccccctg ctgagaggtt aaggctaatg
    35281 tttccttggc tgtaggcatt agtgctatta ggtgatcacg cgcttcctgc tctcgggtaa
    35341 agaaggccag caattctgaa aaatccagct gatgtgcctc tgctaacctc ttcaaaagct
    35401 gtccgatgga ttcttgaata atcgtatcca taacccaagc ctcatcaaag ggcagctgat
    35461 aggtctgata caataaacct agcgcctgac gaatagcctc agaggattgg actagagttc
    35521 catcaaagtc ccaaatgaga ttaactgtca caatccttac ctcttaaatc aatccaataa
    35581 cgagcaatag cctgccctgc taagcttgta gtagggtaat catctgccac ctgaacaata
    35641 tcctctaaaa taccaccagc cttttcaatg gtttttcgac tggctatatt atctttatta
    35701 gctgttatta agacacgctt gatcccacgc tcttgatatt gctgtaatgc aaaggccagc
    35761 aagtctgtca taattccacg cccgcgataa tctgtccttg tcacatagcc aatatgtccg
    35821 ccaattgttg ctaagtctcc tttttccaac tgccagcgac agcctattct agccactagc
    35881 tgaccatcta aaaaatagta ataattagtg ctagtggacc agtcaggatg atcagtttgg
    35941 acctcaaacc gtctagattg ctcaacaaag gctgcaaagt cctctacttt tttggtctca
    36001 acaaaggtat tacctgaagc tttttcagct aacagtatat cctgaaagcg cttaaaggct
    36061 gcttgatcag ctaaagcaat tgttctaatc tctttcatgc ctggctcctt tttattatgc
    36121 taaaaatcaa ctgggcattt ctcaagcatt catcatgcca acgaaaaaga gctgccccta
    36181 gaactgttga tgtaatacta cgtctagagg ctgcccacag gcctttaagc taggctgata
    36241 gacactgact gctgctattt accaatagct caaaacctaa gaggagatgg caactattag
    36301 agatgtgccc ctcttgccac taagtcctct agctctgtca aacgctcttc aaagacccta
    36361 aaggctgctt ctaggtaatc acccttagcc atatcaacac cagccttggc aatcacctca
    36421 agcggataat ctgaatttcc agacttcaga taggtcaagt agtgatcaat atcctcttga
    36481 gtaccatgca cgatcttatc agccaagtag ctggctgcag caaagcctgt tgcatattga
    36541 tagacatagt agttgtaata gaaatgcgga atgcgagccc actcatactg gataaaatgg
    36601 ttgtcctctt tttttaagcc ataatatttt tcgtttaaat cagcatagag attattgagg
    36661 tattcacttg ttaacacctc gccattttga tccgcctgat gaatagcgtg ctcaaactca
    36721 gcaaactgtg tttgacgaaa aaccgttcca cgaaaaccat ctaggtaatg attcaaaata
    36781 gcaaagcgct ccttatcatc ctgcacctca tgtaacaagg cctcagtcat gatattttca
    36841 ttagtggttg aagcaatctc agctaagaaa atgctgtaat ctccatacac gtaaggctgt
    36901 gtttcacgcg taaaggttga gtgcaggcta tggcctgtct catgcactag cgtatagagg
    36961 ttatcaagcg tgtcctgcca atttaagagc ataaaggcat tggtatcata ggaaccacca
    37021 gagtaagctc ctgagcgttt gcccttattg acatgcacat caatccaacg ctctgtaaag
    37081 gcacgatgca cacgctctga ataatcctgg ccaaaaacag ccaaaacctt ctctgctttt
    37141 tccaaggcct catcatagcc gatagcaaga tctgtctcag ataaaggagt ataaacatca
    37201 tacatcttta gatcatctaa accaagcacc tcttgacgta gcttcaaata acgatgaagc
    37261 agcggcaaat gcttattaac gttttctagt agggtatcgt aaacagcctc tgggataaag
    37321 ttggctgaca tcgctgcctg acgggctgaa gcatatttgt gaacacgtgc cttataattt
    37381 tgcaccttta cattggtttg cagggtttta gcataggtgt gctggaattg ctcataagta
    37441 ctatacatgg cttcataggc agccctacgc accttgcggt ctttcgattc catcaagcta
    37501 atgaaattac catgtgttag ctcaacctct tctcccttat catttgtcac aataggaaaa
    37561 gcaatgtcgg cattatctag gatactaaag gtctcctcag caccattaaa gatttcttgt
    37621 gcccctgcta atagctcctc ctcagcctga ctaaggacat gctcacgcgt cttgaacaat
    37681 ttatcaaaga aatggtcata gactgttagc tccggtgtct cagctaagaa ggcttggtag
    37741 gcttcctgac ttaaggccat aaattctggc tcatagaatg aaaaggcttc actaaattta
    37801 gcataaatac cagaggcctt agcttgatat tcttgatact tggcaactgt cgtatcctga
    37861 tcatttttca tgctagcata aacataaacc ttttcaacac gacgagccag ctccaaatgc
    37921 agctctgtga tatctaagag actgctgctt gaatccaaca aatgcccagc ctgctgcctt
    37981 gcagcctcaa ttgctgccag cagactatct gcctctgtct cccaagctgc gtctgttgca
    38041 aaaatagtgc ttaaatccca agtgtacttt tcctctagat gactacgatt atctgtcata
    38101 cggacctcct aagtttctat tactaatcat tttaacataa tatgctggtg aaaaaagctt
    38161 ttgcacctct ttatttgctg cttttgcgta atatttttca aagcaatcgt aatagtggct
    38221 caaatcctca tgaatctggc aaaagccagc tgagcaagca atcggcttaa cctgtggata
    38281 ataagcctct aggggcctat caagcaggtt atccccagct agataagcct cttcttgctt
    38341 tttcaaccat ttgctatctt ttgctagtaa ggctttttga atccttctca gcaagtgctt
    38401 atccatctgg agctgatagg ctgacaggcc ttttctttgg taaggcagcc gcaaaaaggc
    38461 caacaaatca tcatctaagg aacaggtctt tactagatag ctgaccttac caaataaatc
    38521 ctcatgaatc
//
LOCUS       DARYYD010000018        38080 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.018, whole genome shotgun sequence.
ACCESSION   DARYYD010000018 DARYYD010000000
VERSION     DARYYD010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38080
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.018"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(244..375)
                     /locus_tag="TV188_000814"
     CDS             complement(244..375)
                     /locus_tag="TV188_000814"
                     /inference="COORDINATES: protein motif:HMM:NF022534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534190.1"
                     /translation="MEEETKLNQETMTTMIGKYECYARQLEKLAFVFNYKSELRTKD"
     gene            complement(1484..3430)
                     /gene="thrS"
                     /locus_tag="TV188_000815"
     CDS             complement(1484..3430)
                     /gene="thrS"
                     /locus_tag="TV188_000815"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEL1534191.1"
                     /translation="MITITFPDGAVREFESGVTTFEIADSISKSLAKKALAGKFNGQL
                     IDTTRAIEEDGSIEIITADHEDAFEVLRHSAAHLFAQAAKRLFPKLHLGVGPAIADGF
                     YYDTDNADGQISNEDLPRIEEEMKKIVKENFPCIREEITKEEALELFKDDPYKVELIN
                     EHADDAAGLTVYRQGEFVDLCRGPHVPSTGRIRVFHLLNVAGAYWRGNSDNNMMQRVY
                     GTAWFDKKDLKAYLTRLEEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRT
                     LERYITDKELASGYQHVYTPPLASVELYKTSGHWEHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVYKNHVHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSYRDPKDTHKYYDNDEMWENAQSMLKAA
                     LDEMGADYFEAEGEAAFYGPKLDIQVKTALGNEETLSTIQLDFLLPERFNLSYIGADG
                     EEHRPVMIHRGVISTMERFTAILIETYKGAFPTWLAPRQVTVIPISNEAHIDYAWEVA
                     KILRDHGIRADVDDRNEKMQYKIRASQTSKIPYQLIVGDKEMQDKSVNVRRYGSKATH
                     TEAISAFVDNILADIARKSRPAEG"
     gene            complement(4021..5355)
                     /locus_tag="TV188_000816"
     CDS             complement(4021..5355)
                     /locus_tag="TV188_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEL1534192.1"
                     /translation="MRVGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFTTTDKH
                     VKRFEDPTIIRLPSVPFVSFTDRRVVYRGLISSYKIAKEYHLDIIHTQTEFSLGLLGK
                     MVGKALRIPVVHTYHTQYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL
                     NLLEGYEVTIPKRVIPTGIALENYVREDIKKEDVAALRKELAISDDETMLLSLSRVSY
                     EKNIQAIIHQLPAVLSENSRIKLVIVGDGPYLQALKELAVSLGVEDHVVFTGMIAHDQ
                     VGLYYKACDFFISASTSETQGLTYIESLASGKPIIAHGNPYLDDLITDKMFGTLYYAE
                     SELSDAIIDAILETPQMNQRLLDEKRYEISAQHFGKSVYTFYLDTLISRHNKETKKLS
                     LYLNRTEKSGSIKLVQGAIHLPKRAAKATALTSVKVLKAPIKLVNAIRDFLD"
     gene            complement(5357..6355)
                     /locus_tag="TV188_000817"
     CDS             complement(5357..6355)
                     /locus_tag="TV188_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEL1534193.1"
                     /translation="MKVLLYLEAENYLRKSGIGRAIKHQAKALSLVGQEFTTDPKDDY
                     DLVHLNTYGLKSWLLMSKAQKAGKKVIMHGHSTEEDFRNSFIFSNLVSPLFKAYLCRF
                     YNKADAIITPTPYSKALIEHYGVKTPIFAVSNGIDLEQYGANADKEAAFRRYFNLKEG
                     EKVVMGAGLFFLRKGIDEFVKVAEMMPDVRFIWFGDTNKWVIPARVRQIVNGKHPDNV
                     IFPGYIKGDVYEGAMTGADAFFFPSREETEGIVVLEALASRQHLVLRDIPVYEGWIDQ
                     DSAELANDTSGFVAALRRILSGESNKTEAGYRVAEGRSLDRIAHQLVAIYQKVMEL"
     gene            complement(6651..8126)
                     /locus_tag="TV188_000818"
     CDS             complement(6651..8126)
                     /locus_tag="TV188_000818"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1534194.1"
                     /translation="MSHQLLMQAFEWYLPADGRHWQRLKSSIPELQQLGVSQLWLPPA
                     FKGTSSDDVGYGVYDLFDLGEFNQNGTVSTKYGSKEDYLQLIAALKEAKIKPIADVVL
                     NHKANGDHKERFSVIKMNPENRQQALTEPYEIEGWTGFDFPGRQNTYNDFKWHWYHFT
                     GLDYDAKANETGIYMITGDNKGWANDELIDDEHGNFDYLMYNDLDFKHPEVIQNLQDW
                     AKWFIETTGIEGFRLDAVKHIDSYFIQTFINDIRTQLKPDLEVFGEYWKSDQESMEDY
                     LEATKAQFALVDVALHMSFFNASQQGADFDLTTIFDGSLVASRPDLAITFVENHDTQR
                     GQALESTVEEWFKPLAYGLILLRQEGKPCLFYGDYYGISGDYPQQSFKEVITKMAELR
                     QQLVYGEQIDYFDHANCIGWTCLGDDQRPQPLAVVLSNGDAGWKHMEVGQAYAGQVFC
                     DFLDNCQETVVVAEDGWADFKVEAGSISAWVLQKAQPKEEA"
     gene            complement(8196..9197)
                     /gene="ccpA"
                     /locus_tag="TV188_000819"
     CDS             complement(8196..9197)
                     /gene="ccpA"
                     /locus_tag="TV188_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002264971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEL1534195.1"
                     /translation="MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFSILAKGIDDIAAMYKYNIVLASS
                     DEDDDKEVNVVNTLFAKQVDGIIFMGHHLTDKIRAEFSRSRTPIVLAGTVDLDHQLPS
                     VNIDYKAAVADVVDILAKDHQSIAFVSGPLIDDINGKVRLAGYKDGLKKNKLDFKEGL
                     VFEANYSYKEGFELAQRVINSGATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSN
                     DSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEILLNHGIKKRGTTK"
     gene            9371..10456
                     /locus_tag="TV188_000820"
     CDS             9371..10456
                     /locus_tag="TV188_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1534196.1"
                     /translation="MTKLDQIRLYLNQEKAELAIFSDSVTINYLTGFLCDPHERQMFL
                     FVYHDKAPVLFVPALEVARAEQLLDFPVFGYVDSENPWEKIKSILPSTAAKTIYAEFD
                     HLNITKFQGLQSVFSGRFDNLTPYIQRMRLIKSADEIQKMLIAGEFADKAVNVGFDNI
                     SLDVTETDIIAQIEFEMKKQGISKMSFETMVLTGNNAANPHGIPGTNKIENNALLLFD
                     LGVETLGYTSDMTRTVAVGKPDQFKLDIYQLCLEAQLTALDMIKPGVTAAQVDAAARQ
                     VIEKAGYGDYFNHRLGHGIGMDVHEFPSIMAGNDLILEEGMCFSVEPGIYIPGKVGVR
                     IEDCGHVTKDGFELFTQTPKELLYFEG"
     gene            complement(10630..12213)
                     /locus_tag="TV188_000821"
     CDS             complement(10630..12213)
                     /locus_tag="TV188_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011226359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534197.1"
                     /translation="MKSILQVISKWQLCLYSLLALLYSLQGLLLSVLIQIAGQIDMNN
                     KGMVLLFGLGGVAFFVFIYMCMYLNNILARSMVRAFNCLIAKKALYHFYHKQLNYFTS
                     ALNSFLTQDIPMFWQEYLVPLFIYPVFGLSILASVLYLLLQDIYIGIAFTIGGFLMII
                     PQFVFNHLLQSRGLELSQAREKSLASITDFTKGADTIQSNQANEAFAHHVLEMIQHME
                     DKQYSYYTTHNLVMFWTGPLKGIGLVSPLIIGLLVMSYSSLSLTTLIAMITASTNLVS
                     PLQQLLEATSSLQSATAVKEKMVRVLALEEETKHQALTPTDDLTLDIYFKRLDKYFDH
                     RLIFQGIDGHISAGHKTLLTGASGSGKSTLFALLCGEDKDYSGTIYFEAANGKRYFPS
                     YDVVSLIHQKPYIFEGSLRDNLTLFQDYSDQRLKEILQQVHLWNELNGDLDLHLDGQN
                     LSGGQIMKLEIARCLLILKPILLADEVTAALDKESAREIRELLHSLPCTMVEIAHKYN
                     AQSYDCIYHLKDKELVRCS"
     gene            12451..13302
                     /locus_tag="TV188_000822"
     CDS             12451..13302
                     /locus_tag="TV188_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1534198.1"
                     /translation="MNIREKFKAIRKQRRLSLKTLGKIAGSATSISDFENGKTNLSND
                     VLLQLLGFMIVEINELFEWEDFHEKELVEAIKQIELAIKSKHIPALSQLQQDFQSLSK
                     TKEQYIYHIISLILTITIAEYQNKEIDPHIMSELTDYFFFLEYWTNLDVGLLGNIVHY
                     MTTDALILLTNDILEHTPQVLRNNLDRIRIDTVLNCLTVLINRKEEKASRTLLKLLFN
                     KHYPNYFAFEKLYLHELQAVYDFNWKDKEQALAAHHVILATISLLFTADEAKEWDSFF
                     QESTSSL"
     gene            13563..14231
                     /locus_tag="TV188_000823"
     CDS             13563..14231
                     /locus_tag="TV188_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEL1534199.1"
                     /translation="MSHKSIHQQLRNAFSFRTAVRVYNDQKIAKEDLDLILDAAWLSP
                     SSIGLEAWRFVVLENEAVKHELKEVSWGAVYQFETASHMILLISEKNARYDGASIKQS
                     LLRRGITDEQALASRLACYEAFQKHDMKIADDPRALFDWTAKQTYIALANMMTTAAFM
                     GIDSCPIEGFNYDKVNAILAKHGIINPDTEGISSMLSLGYRLRDPKHSQTRKPREEVI
                     SFFN"
     gene            14346..15272
                     /locus_tag="TV188_000824"
     CDS             14346..15272
                     /locus_tag="TV188_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEL1534200.1"
                     /translation="MTLLSVIIPCFNEEDTIIPYLEEMKQIEAAMTSQLAFEYLFIDD
                     GSTDQTLSVLRELAGRFSNVHYLSFSRHFGKEAGLLAGLEEAKGSYITVMDVDLQDPP
                     ELLPLMYSKLQEGFDVVATRRQSRQGEPAIRSFFARLFYRLVKHVSNTEIVDGVRDYR
                     LMTRQVVDSILELGEVNRFSKGIFSWVGYNTAYISFDNRKRQYGKTSWNFLELLNYSI
                     DGFINFSEMPLTIATWTGTLSFLLSLLAICFIVIRKLLFGDPVSGWASTVSIMLFIGG
                     IQLFCMGIIGKYISKIFLETKKRPVYIIKEKK"
     gene            complement(15256..15444)
                     /locus_tag="TV188_000825"
     CDS             complement(15256..15444)
                     /locus_tag="TV188_000825"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534201.1"
                     /translation="MTLSRLFRCEADARSHTKKDLMVLIGTIKSFCRACHDEGNQSLS
                     ASLAADRGLDDCSVISFL"
     gene            complement(15556..16023)
                     /gene="smpB"
                     /locus_tag="TV188_000826"
     CDS             complement(15556..16023)
                     /gene="smpB"
                     /locus_tag="TV188_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEL1534202.1"
                     /translation="MAKGEGNVLAQHKKARHDYHIVETVEAGIVLTGTEIKSVRAARI
                     QLKDGFAQIKNGEAWLVNVHIAPFEQGNIWNADPERTRKLLLKKREIQHLADELKGTG
                     MTLIPLKVYLKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIRRVMKSVNRR"
     gene            complement(16026..18350)
                     /gene="rnr"
                     /locus_tag="TV188_000827"
     CDS             complement(16026..18350)
                     /gene="rnr"
                     /locus_tag="TV188_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEL1534203.1"
                     /translation="MMIENITNYLKEHGQSNIHDLAAALEMTDARSFPRLIKAISKME
                     GKGLLSFSDEGEVFLRAPQQKKPEIRVQGIFRANKAGFGFLSVDDNEDDIFIGRDDVG
                     YASDGDRVEAVIKKPANRLKATAAEARVVAIVERSLKTVVGRVILDDDHPKYAGYIKS
                     KNQRIQQRIYIAKSPIALDGTEIIKADIVQYPKAGQDYFVGTVCDIIGHQHDVGIDVL
                     EVLESMDIVSAFPDDVLAEANAIPDAPSDQDLMGRVDLRKETTITIDGADAKDLDDAI
                     HIKRLANGNVELGVHIADVSYYVTEGSALDREAAARGTSVYVTDRVVPMLPERLSNGI
                     CSLNPKVDRLTQSAIMEIDHQGHVVDYQLCQSVINTTFRMTYSAVNQMIAGDSEALRE
                     FDRIADDVSTMVELHQILEAMRVKRGALNFDTQEARIIVNDKGMPVDVVLRQRGVAER
                     MIESFMLAANECVAEHFSRAGLPFIYRVHEEPKAEKLQTFIDYASAFGIQIQGTANKI
                     SQEALQAFMAKVEGSPGAEVLNMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRR
                     YPDLLVHRMIREYNQITQEKVDHFAQVIPELAVSSSQLERRAIDAERVVEAMKKAEYM
                     ADYIGDVFDGVIASVVKFGMFVELPNTIEGLVHITNLPEYYHYNERTLSLKGERSGKV
                     FRAGQPIRVRLVRADKETGDIDFDYLASDYDVVEKTTRSAKAKHKHRQKAASRASRSK
                     ESKPSKPKSKQKTRKKAKKPFYQKAAKKKGRKRS"
     gene            complement(18437..18673)
                     /gene="secG"
                     /locus_tag="TV188_000828"
     CDS             complement(18437..18673)
                     /gene="secG"
                     /locus_tag="TV188_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEL1534204.1"
                     /translation="MYDLLLTILLVLSVLLVIAIFMQPQKNPSSNVFDSSGSEALFER
                     TKARGFEAFMQRFTAVLVFFWLGIALVLAILSSK"
     gene            complement(18719..18865)
                     /gene="rpmG"
                     /locus_tag="TV188_000829"
     CDS             complement(18719..18865)
                     /gene="rpmG"
                     /locus_tag="TV188_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1534205.1"
                     /translation="MRVKIHLECSHCGSKNYLTSKNKTSHPEKIKVPKYCPKERKVTL
                     HVES"
     gene            19353..21185
                     /locus_tag="TV188_000830"
     CDS             19353..21185
                     /locus_tag="TV188_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1534206.1"
                     /translation="MRKTMKKMLAASTLCIIMSGSFISGSARVLAEKYYGFNDGTGEH
                     SPFPVYVTPITKPNRNTAKVVYCFNKDMKWPETWDKAAPKKPDNLPLYYDMEGTDQLF
                     STYASGQLTPNVSKVLANIMAKGYPNNNEFAHHFKLTPNSAVKVTQIAVWTVTDNLKN
                     YSQYSLTREEEAALNYLTDKNGDDFSDSIKLKLYIPQNPRTIKYQNLLGYDLIVKTPE
                     KKDNCKCTKIYIEDNGKDGYYLYIYYDNNENNRYDSDKDSLLQKKYIKNGKDGKPGRP
                     GVPGLPGPAGPQGPRGDKGETGERGPKGEKGLDGKPGEKGPKGDTGKDGKDGQPGPQG
                     PKGDPGRDGKDGEPGKPGERGEKGPQGERGPQGLPGPKGEPGIPGPKDEDGKDGAPGH
                     DGQPGPKGEKGDPGQQGIPGPKGEPGRDGKDGEKGERGEQGPQGERGEQGPQGERGEQ
                     GPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPQGERGEQGPRG
                     ENPTPTPDPMPQPEPQPEPQPMPDPAPKPESKPEPKPIPQPEVKPQPETKPQQPNKPS
                     TITSQSSGKSLPKTNDTGSLITAFGTGLLTLLGLGFLAKRKRKQ"
     gene            21497..22537
                     /locus_tag="TV188_000831"
                     /pseudo
     CDS             21497..22537
                     /locus_tag="TV188_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677601.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
     gene            complement(22700..23293)
                     /locus_tag="TV188_000832"
     CDS             complement(22700..23293)
                     /locus_tag="TV188_000832"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEL1534207.1"
                     /translation="MTKVIGITGGIASGKSTAVALIRQAGYQVIDADQVVHELQKKGG
                     KLYQVLLETFGQDILLPSGQLDRPKLAELLFAHSENMAKSSQQQNAIIREALAKQKEE
                     LSQTEAIFFMDLPLLVELGYQDWFDAIWLLYVDEETQLKRLMKRNQLTELAARQRIAS
                     QLPMSQKRAYADLVIDNTGDFQALETQISKALHDLEA"
     gene            complement(23290..24111)
                     /gene="mutM"
                     /locus_tag="TV188_000833"
     CDS             complement(23290..24111)
                     /gene="mutM"
                     /locus_tag="TV188_000833"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEL1534208.1"
                     /translation="MPELPEVETVRRGLERLVVGKQIAAVTVRVPKMVKTDLEHFVMT
                     IPGQQVQGVDRRGKYLLFDFGQLVMISHLRMEGKYLLFPDTVPEHKHFHVFLTMTDGS
                     TLVYQDVRKFGTFDLLPKAELAAFFQKRQLGPEPTKQTFQLKTFEAALLASKKTIKPH
                     LLDQTLVAGLGNIYVDEVLWAARVHPERRSASLKKAEIKRIHDETIRILQLGIEKGGS
                     TVRTYQNTLGMNGSMQHYLMVYGQTGKPCQRCGTSIVKLKVGGRGTHVCPRCQKQ"
     gene            complement(24526..26325)
                     /locus_tag="TV188_000834"
     CDS             complement(24526..26325)
                     /locus_tag="TV188_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEL1534209.1"
                     /translation="MERFQISDQFYLDGRSLQILSGAIHYFRIHPDDWYHSLYNLKAL
                     GFNTVETYVPWNLHEAREESYDFSGQLDVEAFLTLAQQLGLYAIVRPSPYICAEWEFG
                     GLPAWLLTKNCHIRSSDPVYLAYVRRYYEELLPRLARHEWQQGGNILMFQLENEYGSY
                     GEDKAYLTAVKGFMEEHLSAPLFTADGPWRATLRAGSLIEDDVFVTGNFGSRAQENFA
                     DMQAFFSEHGKHWPLMCMEFWDGWFNRWHEPIIKRDPEERADAVMEVLAQGSINLYMF
                     HGGTNFGFMNGCSARKQLDLPQVTSYDYDAILDEAGNPTAKFYAIQKRLTAELSEIEV
                     TPPLIKPLMSLPLIGLKDKVSLFSTLEHISSCQTACYPSNIEALGQSTGYILYRTHLL
                     KDKREDERLRLIDSRDRAQVFLDGQKVATQYQETIGDDIIINQQHALSQVDVLIENMG
                     RVNYGHKLTAPSQSKGLGRGMMADLHFVTNWEMYCLPLDDLSQLCFDGDFYEGQPGFY
                     HYQFECHEPEASYIDMTGFGKGCVFINNHPIGRFWEVGPLLTLYIPKGYFNKGLNDIV
                     IFETEGVYQDSIRLVDRPISIDYPQADDRTDQT"
     gene            complement(26486..31126)
                     /locus_tag="TV188_000835"
     CDS             complement(26486..31126)
                     /locus_tag="TV188_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 16 glycosylhydrolase"
                     /protein_id="HEL1534210.1"
                     /translation="MLFNPIGKEQIRKYAIKKLSVGVASVCVGIGLAAGLPVAVYADD
                     VSEVSLQQPTKAAVTEISHEQEPQATDTDSEALVVSEETTVDEAVVANAVTSNAADQT
                     ADEEKSNAPIELNKVANGGFDNDYVSNKNQWQYREGGHSVLTTENGNSYAEVTSGTLD
                     EHILQKVSTTVGKTYTLEADVKVEADTPHNGLYLTAKESNHNLQGPVIKEVSLTDTDG
                     TWSHIKLSFTATTSETFVGLVKWLEASSPEALAASASIDNVSVVEENDYELIWQDEFS
                     GDRLNQENWGYELGSIRGNEQQHYTDSTENVYLDNGNLVLNVTERYGEDRYANPRGGT
                     SARQVIYDSGSVRTVGKQEFLYGRIEARAKLPKGKGAFPAFWTLGADFTLDGDIASTQ
                     GYGWPSTGELDIMELIGAPNGEHEGELAEGDQSNKTVYGTPHFYYIKGDADKDGSYSP
                     TALGGNLTLSDDFYDDYHIFGINWYPDKIEWYVDGIVYNTMYLTGDDRLEAAAAAFNK
                     PQYLQFNLATGGNWSKNAGYYLASDETAFVIDYVRYYQDAEQKAASEAYYASQPVLKG
                     VKDLTMLEGTSPDLAQAVTTDQEGYVVDFSVENEYLFTNKGGNTNAALQAAGRDDLSA
                     LSELAPGIYNIYYSAVPYNADLGSTVTPTAKIAREVAILTVLPKEGLIGKKGEPLSTV
                     ALPANWQWVTPEEILGSAEHYQIKYTTEGGRAVYTSIEASYISDQPISDQASILVDLG
                     NAILDATAEKAAVTDDEALGKLDDVMNLTQGTVTIRYRLDTADTTVRSSSPLALLSIS
                     NQASANEYASFFIEPKNNKIGLEFKGAEVPIVKVGSGFNLLTNSDWQTISYVFTGSRL
                     KIYLNGDLYGEADFAGFMKQLPWKASADTLTIGGLKRTYDGESVLHWGLKGLVDQVLI
                     DTDVYDLTDIAKAHQPTLRPVTGEKTNVWDKYDEGVFEYRIPSVVKTPSGTLIAAADA
                     RKKHYNDWGDVATVVRISHDDGKTWSNNITVLDMPTQPYFTTQYSLADWNTNMTQSAF
                     SIDSTLLTDASGKLYLLVDVFPESQGAVASKAGSGYELINGQYYLNLYDFDNNKYTVR
                     EGGIVYDQSGHQTDMYVDEGNFETAFSTRGNLYQTEAGEDILLGNIYLRSGRTKQGIT
                     REGSQTAPLFTYMTSFLWLLTSEDEGQTWSTPLDITPQIKEDWMGFLGTGAAAGIEID
                     AVNAEGEQVKRLVFPIYYTNQQNATSASLGRQSSANIFSDDGGQTWQRGESPNDGRIY
                     GHNQQTTSKDFDTSVTELTENQIIQLNNGHLLQFMRNTGKTIVIARSTDYGMTWDDNP
                     TITDLPEPYVNLSAIHMMVDGKEYVVLSNPLGEPSGEQLTIRNQRMKGILRVGEVLED
                     DSIHWVASTIFEPKRFAYSSLVQLDDERVGLLYEYSGQITYSTFNIKQMISDQFREDK
                     AEIEEVTITSAAPKQNGKVSITIQMTFNQPMFILGDRQLAVTVNGVDKLASYVSGDGT
                     DTAIFELSLESMPEGPITVLPQFDHTIVETKYGIRLTDDKAYTVSYPAAVTA"
     gene            complement(31299..32646)
                     /locus_tag="TV188_000836"
                     /pseudo
     CDS             complement(31299..32646)
                     /locus_tag="TV188_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(32711..34027)
                     /locus_tag="TV188_000837"
     CDS             complement(32711..34027)
                     /locus_tag="TV188_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1534211.1"
                     /translation="MTKFEDFIQQKLVPVAGRLGSNRFLIAIRDGITYAMPLILIGSF
                     LMVIASLPIPGWEAWLGEIGVSTYLWKGVDSSFNLIALVAAFGISYSLAKQYKADGIS
                     AGIINISAFLTVTPFTVSFVNESGKALGEVAGIAPSYLSSGGLFVAIVLGLVNGYAYQ
                     WFMKKDIRIKMPEGVPPAVSKSFSAIIPGAVIIVFWLAVYAFLDHFSLPNVHDIVKSV
                     LGVPFGLLGSTLFGNFIVVLLNGFLWFCGVHGGNVLNNPIMKPIWLSNLTENMAAHKA
                     GQELPHVFTSVFMDNFVFIGGAGATIGLVLALAWLARRRKASQQAKVLSPLTLIPGFF
                     NINEPTMFGLPVVLNLLTVIPFVLAPVMNLFVAYFAFASGIVPGTYADPGWTMPPVIS
                     GFLATGSWQASVLQLVLIILDILLYLPFIINVERRWQASEQTKNEG"
     gene            complement(34020..34352)
                     /locus_tag="TV188_000838"
     CDS             complement(34020..34352)
                     /locus_tag="TV188_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1534212.1"
                     /translation="MEDKQLETIMGLIMHGGSAKSLAMEAIAFAKKGELNQAQESLKQ
                     ADKALVQAHHAQTDMLTQEARGNATPVSLLLVHGQDHLMTSITFVDLARELVSIYERL
                     TSQGGNND"
     gene            complement(34362..34679)
                     /locus_tag="TV188_000839"
     CDS             complement(34362..34679)
                     /locus_tag="TV188_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1534213.1"
                     /translation="MSKKQIMLACAAGMSTSLLVTKMEKAADNRGLEADIFALPLTEA
                     EDYALSHPVDVVLLGPQVAYQLSAFQESLAEKDIPVAVVPMVDYGMMNGDKVIALAES
                     LMK"
     gene            complement(34703..35602)
                     /locus_tag="TV188_000840"
     CDS             complement(34703..35602)
                     /locus_tag="TV188_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEL1534214.1"
                     /translation="MKTRLLSASSSEMLQLTSLELKQAIKASEGRTIVSENVAPRPSW
                     TGDDLTNAEVAAAFSADLILLNCVDVFDVQISGLPATDQPILELRRLVGRPIGVNLEP
                     IDLDVDMTEKRLELVEGRQATAKTFQEIEALGFDFVCLTGNPGTGVSNNQIERAIQQA
                     KHYFSGLIIAGKMHAAGSNEAVIDLETVRRFIEAGADVILVPAVGTVPGFTEGDLRAI
                     VEEVHAHDALVMSAIGTSQEGSDTTIVRDIAIRNKICGVDIHHIGDAGYSGIAPVENI
                     FALSDAIRGKRHTIVRMSRSIRR"
     gene            35782..36984
                     /locus_tag="TV188_000841"
     CDS             35782..36984
                     /locus_tag="TV188_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEL1534215.1"
                     /translation="MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITK
                     ELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYA
                     KHNQQIDPSISSYYKADYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
                     NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYERQAHNHNFIFFHVGRGMHCS
                     YMYKGVIYSRHNAVVGEIGHTIVNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYA
                     PNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQI
                     YLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELY
                     LNYKNKYD"
     gene            complement(37147..37623)
                     /locus_tag="TV188_000842"
     CDS             complement(37147..37623)
                     /locus_tag="TV188_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEL1534216.1"
                     /translation="MTQDYISYIRSKVGHDNIILTFAGGILANAEGKVLLQLRADKKT
                     WAIPGGAMELGESSAETCRREFYEETGITVEPLRLLNVYTNFEETYPNGDKVQTVVML
                     YEVIAKADKAITDYQNDETLRLGYFSREEIAELSSISDKHRLMLAEYFAGEFQMGH"
     gene            complement(37768..37977)
                     /locus_tag="TV188_000843"
     CDS             complement(37768..37977)
                     /locus_tag="TV188_000843"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534217.1"
                     /translation="MTQVRVYLWLSCDDGDNIESNSMTSRKPLAKEDIKKVIVACLSF
                     SEVGYRLKEKGLGIRVSFWLLKSVI"
BASE COUNT        11528 a         9101 c         7095 g        10356 t
ORIGIN      
        1 gtaacatatg aaattgagat acaaaaatag acagtagcaa acagaaaatc aacattttat
       61 gcttcatggt cagcactcct ttaagtattg tttttacact tatcgtatga ctaacatttc
      121 agatttgttt cagattctag aaaataatac ttactattgt gcttatttaa gtccaaaaat
      181 tagcattaca ctcattaagt atctgagatt aatctagcta acattctaaa ttgttttctc
      241 ccactaatct tttgttctta attccgactt ataattaaag acaaaagcta atttttctaa
      301 ctgcctcgca tagcactcat acttgccaat cattgttgtc atcgtctcct gattgagctt
      361 agtttcttct tccacctgct ccagtttact agctgatatg caagtgcaat ggtcgttttt
      421 tgtgaatcac acctactttg aatctggtaa aatcattcta ctaacaaact tcctgtgtaa
      481 tttctagtag cctaggtagc ctgataaaga gatttcttca aataaaaata accatgtcga
      541 atgccagcgc tccatttctt accagcattt tcattattcc ccagctaaag ctctatccat
      601 gaggctaagt gacctgtgct tagaattaac tcatatccac actagtctca gaaataaaga
      661 ctgaagctat catgatgtca ctactaggaa tgaatgaaat ctagggtttc tacttgacag
      721 tcatagtgag acaaacaagc ggcaatttgc tcttctaaac tcccgatttg tttctaatag
      781 caagcataaa tctccataga ctacccccat agaaaatggt ggtgattgga gaaatcacca
      841 ttaagtgctt cacgacgttg aggagctttc ttcttcaaac tagtataaac aattaatgga
      901 ctacttactc tagctgtcat aggcgtttga gcaatcagta gttgaaatag cttgcaaccg
      961 aaagcaccca gcatactctc aatgcggatc ggaagttcaa tgccacctaa ctgtagaatt
     1021 ttataatgca aattgtcctt tattaagaac cttattgatc attttaagct ttagttcggg
     1081 agaggaacga atctttttcc ttagcagctt tacaatcaat taatcgtgct aaatacttta
     1141 aatggaattg attgatatca aattgtttga atgaataact ctggttttgt aggccgcaga
     1201 tttctacctt gtcttgatgt cttaatgtca tgttaaaagc accccattcg ttagatagtt
     1261 tgtctaactt ttggggcgca gttcattcat tagatttttt atctaatttt tgagaagcag
     1321 tttacttctg atgagggctt ctatattgct ttcattagtt ctatgagtga gagcaaagct
     1381 cttgtagcta tttgtcccag atttttttat gtcatctgtt ttgcaagtca agctgacgtc
     1441 tgcttaatca gcctatctaa aaccagcttg cttggtctgc tttttagcct tcagctgggc
     1501 gtgatttgcg ggcaatatca gccaaaatgt tatcaacaaa tgctgaaata gcttcggtat
     1561 gtgttgcctt actgccatag cggcgcacat taactgactt gtcctgcatc tccttatcac
     1621 caacgattaa ttggtaaggg attttactgg tttgagaggc acgaatctta tattgcattt
     1681 tctcattacg atcatccaca tctgcacgaa tcccatgatc acgaaggatt ttagcaacct
     1741 cccaagcata gtcaatatgg gcctcattgg aaattgggat aactgttacc tgacgtggtg
     1801 ccagccatgt tgggaaagct cccttatagg tttcaatcaa aatagcagta aagcgctcca
     1861 tggttgaaat caccccgcgg tggatcatca ccggacggtg ttcttctcca tcagcaccaa
     1921 tatagctcag attaaaacgc tcaggcagta agaagtccag ctgaatggtt gatagggttt
     1981 cttcatttcc aagggctgtt ttgacctgaa tatcaagctt tggcccgtaa aaggcagcct
     2041 ctccttctgc ttcaaagtaa tcagcgccca tttcatcaag cgcagccttc agcatgcttt
     2101 gagcattttc ccacatctca tcgttatcgt aatatttatg tgtatccttt ggatcacgat
     2161 aggacagacg gaagcggtaa tctgttaggt taaaatcctc ataaacgtca ataatcagct
     2221 gaagagctcg ctggaattcc tcctgaatct gctctggcgt cacaaacagg tgcccatcgt
     2281 ttaaggtcat ctcccgcacg cgctgaagcc ctgaaagagc ccctgatttt tcatagcggt
     2341 gcatcatacc aagctctgca atacgaatcg gcagctcgcg ataggaatgc acatggtttt
     2401 tataaacctg aatatggtgt gggcaattca ttggacgaag gacaaattct tcaccatctc
     2461 ccatatccat tgtcgggaac atatcctcct gataatgctc ccagtggcct gatgttttat
     2521 aaagctcaac tgaagcaagc ggcggagtat aaacatgctg atagcctgat gccagctctt
     2581 tatcagtgat atagcgctca agcgtgcgac gaatcgtcgc tccatttggt agccaaaatg
     2641 gcaagccttg tcctacctcc tgagagatca taaacaaatc aagctccttg cctagcttac
     2701 ggtgatcgcg ctccttagcc tcctcaaggc gtgtcaaata ggccttgagg tcctttttat
     2761 caaaccaggc tgtcccatag acacgctgca tcatgttatt atcgctattg ccacgccagt
     2821 aagctccagc tacatttaac aaatgaaaga cccgaatccg acctgttgac ggcacatgag
     2881 gaccacgaca aaggtccaca aattcaccct gacggtaaac agttaagcca gccgcatcat
     2941 ctgcatgctc attaatcaac tcaaccttat aagggtcatc cttaaaaagc tcaagagcct
     3001 cttcttttgt gatctcctca cgaatacatg gaaagttctc tttgacaatt tttttcattt
     3061 cctcttcaat gcgaggcagg tcttcgttag agatttgacc atcagcatta tctgtatcat
     3121 aataaaaacc atctgcaatg gcagggccta caccaagatg cagcttgggg aacaagcgct
     3181 tagcagcttg agcaaacaag tgagccgcag aatgacgcag cacctcaaaa gcgtcctcat
     3241 gatcagcagt tataatttct atactaccgt cctcttcaat ggcgcgcgtg gtatcaatta
     3301 attgaccatt aaacttacca gccaaggcct ttttagctag agatttgctg atagagtcag
     3361 caatctcaaa ggttgtgaca ccagattcaa attcacgcac cgcgccgtct gggaaagtga
     3421 ttgtaatcat ctgttttctc ctataaacca tctagatact taaaacaagc taatcaagca
     3481 gggctatatc tcccaagcct tctgctgcta cgacaaaata aaaactgact gcctcccaaa
     3541 ggacgcaatc agcgtggttc cacctttatt tatgcatgac aaagaaatcc tgtcctgcac
     3601 ctcagcttgg ctatatcgtg accaccgttt tatgtttgca taaaagcaag gaaggagtat
     3661 tacactagac accctgtgct cttctcacca accagcactc gcttaaagga tgcgacctaa
     3721 tctaacttgt cttcctgatt attatagcaa tatttggaaa taattcaagt gatttttcct
     3781 aaaaaagctg agataagccc acagacctcc aagcccacaa ggcaagaatg actaggcaag
     3841 gaaccctgaa acttctgcca caagcctttg aagaacagct caaacaggac ttgccgcctg
     3901 tcgtctcagt tcacaagaca acaaactaaa tcctttagac aaatgattat cctaaagagc
     3961 tatctgctct ctcacgcaga accaaagcct gtaattgcag gcttctttgt ttatttagcc
     4021 ttagtccaaa aagtctcgga tcgcattgac cagcttgata ggggctttga gcaccttgac
     4081 agatgtcagt gcagttgcct tagctgctcg cttaggcaag tgaatcgctc cttgaaccag
     4141 cttgattgag ccactctttt ctgttcgatt gagatagaga cttagctttt tcgtctcttt
     4201 attgtgtcgc gaaatcaagg tatctaaata aaaggtgtac actgatttgc caaaatgctg
     4261 agctgaaatc tcatagcgct tctcatctag cagcctctgg ttcatttgag gtgtttctaa
     4321 aatggcatca ataatcgcat ctgacaattc tgactcagca taataaagtg ttccaaacat
     4381 cttatcggta atcaaatcat ctaggtaggg attgccatga gcgatgatgg gcttgccact
     4441 agcaaggctc tcaatataag ttagcccctg tgtctcactc gttgacgctg aaataaagaa
     4501 atcacaggcc ttataataaa gcccaacctg atcatgagca atcataccag taaagaccac
     4561 atgatcctca acgcctaagc tgacagccag ctcctttaag gcttgaagat aaggaccatc
     4621 accaacaatg acaagcttga tcctgctatt ttcactcaaa acagctggca gctgatggat
     4681 aatagcctga atattcttct cataagacac ccgcgacagg ctcaatagca tggtctcatc
     4741 atcagaaatg gccaattcct ttctcaaggc agcgacatct tcttttttaa tatcctcacg
     4801 aacatagttc tctagtgcaa tgccagtcgg aatcacacgc ttaggaatgg ttacctcgta
     4861 cccttccaaa agatttagca caatccgact tgggcaaata acaccatcaa ggtcctttaa
     4921 atacccacga agcaggggct tgaccatgct aggtcgaatg atcttaccat tagcaatata
     4981 gctcacataa tcctcatact gggtatgata ggtgtgaaca accggaattc ttaaggcctt
     5041 gcccaccatt ttgcccaaca aacctaagct aaactctgtt tgagtatgga taatgtctaa
     5101 atgatattcc ttagcaatct tgtaggagga aatgagccca cgataaacca cacgacgatc
     5161 cgtaaaggac acaaaaggaa cacttggtaa ccgaataatg gtcggatcct caaagcgctt
     5221 aacatgcttg tctgttgttg tgaaaatata gacctcatgc ccctcttttt ccagctcctc
     5281 ctttagggtg cgaatactgg tagccactcc ggaaacctgt ggaaaatagg tatctgtaaa
     5341 tagacctaca cgcatcttat aactccatta ctttttgata aatagccact aattgatgag
     5401 caatcctatc aaggctgcgc ccctcggcga cacgatagcc ggcctctgtt ttgttgcttt
     5461 cccctgaaag aatgcgtctt aaggctgcaa caaagcctga ggtatcattt gccaactcag
     5521 cactgtcttg atcaatccag ccctcataga ctggtatatc gcgtaaaaca agatgctgcc
     5581 ggctggctaa ggcttcgaga accacaatgc cttctgtttc ctcacgactt gggaagaaaa
     5641 aggcgtcagc cccagtcata gccccctcat acacatctcc cttgatataa ccagggaaga
     5701 tcacattatc ggggtgctta ccgttgacaa tctggcggac acgagcagga ataacccatt
     5761 tattggtatc accaaaccag ataaaccgaa catctggcat catctcagca accttaacaa
     5821 actcatcaat cccttttcta agaaagaaaa gccccgctcc catgactacc ttctcaccct
     5881 ctttgaggtt aaaataacgc cgaaaggcag cttctttgtc agcattagca ccatattgct
     5941 ccaaatcaat cccattagat actgcaaaaa taggagtctt aaccccgtaa tgctcaatca
     6001 aggctttaga ataaggggtc ggtgtgataa tggcgtccgc cttattgtaa aagcggcaga
     6061 gataggcttt gaataaagga gacactagat ttgaaaaaat aaaggaattt ctaaaatcct
     6121 cctctgtcga atgcccatgc atgatcacct ttttaccggc cttttgagcc tttgacatca
     6181 aaagccagct tttaagccca taggtattga gatgaaccaa atcatagtcg tcctttggat
     6241 cagtggtgaa ctcctgtccc acaagcgata gcgcttttgc ctgatgctta atcgctcgcc
     6301 cgatacctga ttttcttaaa taattttctg cttctaaata caataagact ttcatactgt
     6361 ctattatagc ctattttatg gtatttttca ctaagagagt taaaaatcag cccttagact
     6421 gattttaggg taaggcttct tctaccccta tactcatctc aaaaatgctt ttaagtcctg
     6481 cttttgctgt catcaaatgg ctgatcttgg taatatcagc tagaccaaga tcgtgaaagc
     6541 tccagctcaa ggctcacgta ttagcccttt caagaaagcc tcccaccttt ctcactggcc
     6601 aaaaagccag caagacctgg ccttttcttc tgattaattc agcctatcag ctaagcttct
     6661 tcttttggct gtgctttttg taacacccag gctgagatag agcctgcctc taccttgaaa
     6721 tctgcccagc catcctcagc aacaacaaca gtctcctgac aattgtctaa gaaatcacaa
     6781 aaaacttgac cagcataggc ttgaccaacc tccatgtgct tccagcctgc atcgccatta
     6841 gacaaaacaa ctgccaaagg ctgaggacgc tgatcatctc ctaagcaggt ccagccgata
     6901 caattggcat gatcaaagta atcaatctgc tccccataga ccagctgctg cctgagctct
     6961 gccatttttg tgataacctc cttaaaactt tgctgagggt agtctccaga aataccataa
     7021 taatcaccat aaaaaagaca gggcttgccc tcttgtcgta aaagaatcag gccataggct
     7081 aagggcttga accattcctc aacagttgac tctaaggctt gccctctttg ggtgtcatgg
     7141 ttttccacaa aggtaatagc aaggtctggc cgactagcca caagactgcc atcaaaaata
     7201 gtggtcaaat caaaatcagc tccctgctgg ctagcattaa aaaaggacat gtgcagcgca
     7261 acatcaacta gagcaaactg agccttcgtt gcttcgaggt aatcctccat agattcctga
     7321 tcagacttcc agtattctcc aaaaacctct aaatcgggct ttagctgggt acgaatatca
     7381 ttgataaagg tctgaataaa ataagaatca atatgcttca cagcgtctaa acgaaagccc
     7441 tcaataccag ttgtctcaat aaaccacttg gcccaatcct gtaaattttg gattacctca
     7501 ggatgcttga aatctaagtc attgtacatt agataatcaa aattaccatg ctcatcgtca
     7561 atcagctcat cattggccca gcccttgtta tcaccggtga tcatgtaaat acctgtttca
     7621 ttagccttgg cgtcataatc caatcccgta aaatggtacc agtgccattt aaagtcatta
     7681 taggtatttt gtctgccggg aaaatcaaag cctgtccagc cttcaatctc atagggctct
     7741 gtaagggcct gctgacggtt ctctggattc attttgatca cagaaaagcg ttccttgtga
     7801 tcaccattag ccttgtggtt cagcacaaca tcagcaatag gctttatttt tgcctctttt
     7861 agggctgcaa tcagctgcaa ataatcctct ttgctgccat attttgtgct gacagttcca
     7921 ttttggttaa actctcccaa atcaaacaaa tcgtaaacac cgtaccccac atcatcagag
     7981 ctagtgccct taaaggcagg cggcagccac agctgactaa cccctagctg ttgtagctca
     8041 ggaatactgc ttttcagcct ttgccaatgc cttccatcgg caggcaaata ccattcaaag
     8101 gcctgcatta atagttgatg actcatctta acctcctaaa aaggacaaac cagaaaactc
     8161 ctagtttgtc ctcaaaactg cctaaacagg cagaactatt ttgttgtccc acgcttttta
     8221 atgccatggt tcaataaaat ttctttttct tctaattctt ccttattcat gatcttagtg
     8281 agcatacgca tgctaacagc ccccaagtca tagaccggct ggctgataga gctcaaattt
     8341 ggacgtgtgt actgaacgac tggagaatca ttgcttgtga taatctcaaa gtcttctgga
     8401 acacgcttac cagcttcaaa aagaccattc aaaaggcctg ctgccagctc gtcctctgca
     8461 acataggcag ctgtcgctcc ggaattgatc acacgctgag ccagctcaaa gccttcctta
     8521 taagaatagt tggcctcaaa caccagaccc tctttaaagt caagcttgtt cttcttgagt
     8581 ccgtccttgt agccagctaa acgcaccttt ccgttgatat catcaatgag cggccctgaa
     8641 acaaaggcaa tgctttggtg gtctttagct aaaatatcca ccacatcagc aacagccgcc
     8701 ttataatcaa tgttaacact tggcagctga tgatccagat caaccgttcc tgccagaacg
     8761 attggcgtac gcgaacgaga aaactctgcc cgaatcttgt cagtcaagtg atgtcccatg
     8821 aaaataatgc catcgacctg ctttgcaaag agggtattca caacattgac ctctttatca
     8881 tcgtcctcat cacttgaagc aagaacaata ttgtacttgt acatagcagc aatatcatca
     8941 attccctttg ccagaataga aaaatagcta tttgcaatat taggaatcac aacaccgact
     9001 gttgttgtct ttttacttgc aagaccacga gcaacagcat ttggacgata atcgagacga
     9061 tcaataacct ctaagacctt tttgcgggta ttttccttta catttttgtt accatttaca
     9121 actcgactaa ctgtcgccat tgaaactccc gcttcgcgag caacatcata aatcgtgatt
     9181 gtatcatctg tattcattct tcatcttcct ttctaactga aaatgacgct ttcaaaaagt
     9241 attttagcat gatttgtaac cactttcaag tattaacggt tgatttttga aaaagttttc
     9301 aaaaattcat aataagcttg cttttttaag tattttttgg aaaaatagaa ggcagaaaga
     9361 aggtttatct atgactaaat tagatcaaat tcgtttgtac cttaatcagg aaaaggctga
     9421 gcttgctatc ttttctgatt ctgtaacgat caattactta actggttttt tatgtgatcc
     9481 tcatgaaagg cagatgttcc tatttgtcta tcatgacaag gctcctgttt tgtttgtacc
     9541 agctttagag gttgcaaggg ctgaacaatt gctggacttc cctgtttttg gctacgttga
     9601 ctctgaaaat ccttgggaaa aaatcaagtc tatcctacca agcacagcag caaagaccat
     9661 ttacgctgag tttgatcatt tgaacattac caagtttcaa gggctgcaga gtgtcttttc
     9721 aggacgcttt gacaatctaa ccccttacat tcaaagaatg cggctcatca agtctgctga
     9781 cgaaattcaa aaaatgctga ttgctggaga atttgccgat aaggctgtca atgtgggctt
     9841 tgataatatt tcacttgacg tcaccgagac agatatcatc gctcaaatcg aatttgaaat
     9901 gaaaaaacaa ggcatcagca agatgagctt tgaaacgatg gttttaactg gtaacaacgc
     9961 tgcaaaccca catggcattc caggaaccaa taaaatcgaa aacaatgccc tgctgctctt
    10021 tgaccttggt gttgaaacat taggctatac tagcgacatg acgcgtacag ttgccgttgg
    10081 aaagccagac caatttaagc ttgatattta tcagctttgc ttagaggctc agctaactgc
    10141 tcttgatatg attaagccag gagtgactgc agctcaggta gatgccgctg ctcgccaagt
    10201 gattgaaaag gctggctatg gcgactactt caatcacagg ctcggccatg gtatcggtat
    10261 ggacgttcac gaatttccat caatcatggc tggcaatgac ctgattcttg aagaaggcat
    10321 gtgcttctca gttgagcctg gtatctatat cccaggcaag gttggggttc gtattgagga
    10381 ctgtggtcac gtaactaaag acggctttga gctcttcacc caaacaccaa aagaattact
    10441 atactttgaa gggtaatagg aggcttaaaa agcctgaaac aaaatgtctc agaccctaat
    10501 atctaaagca acagcacttg gtctgttact tttcatatta caggctattt tctcacaagg
    10561 aaaagtcaaa gcaccccttg atgggaaatc agaggggcaa aagctatttg tactaagctc
    10621 aaaagctaat caagagcacc tgaccagctc tttatccttt aagtgataaa tgcaatcata
    10681 agactgtgca ttatatttat gagctatctc aaccatggtg caggggagtg aatggagtaa
    10741 ctcacgaatc tctctggcgc tttctttgtc tagggcagct gtgacctcat cagccagcaa
    10801 aatcggtttt agtatcagca agcagcgtgc aatttccagc ttcatgattt gcccgccaga
    10861 gagattttgc ccatctagat ggagatcaag atctccgttt agctcattcc aaagatgaac
    10921 ctgctgtaat atctccttta gtcgctggtc cgaataatcc tgaaacagcg tgagattatc
    10981 tcgcaagctt ccttcaaata tgtaaggctt ttgatgtatc aaagacacaa catcatagga
    11041 aggaaaatag cgttttccat tggcagcttc aaaataaata gttccagaat aatccttatc
    11101 ctcaccacac aaaagagcaa ataaagtaga tttcccacta ccactggctc ctgttagcaa
    11161 ggttttgtgc cctgctgaaa tatgaccatc tatcccttga aaaataagcc tatgatcaaa
    11221 atacttatct aacctcttaa agtagatatc aagtgtaaga tcatctgtag gggttaaggc
    11281 ttgatgtttt gtctcttcct ccagagccaa tactctaacc atcttctcct taacagcagt
    11341 tgcagactgt aaactcgaag tagcttctaa taattgctgc aagggagaga caagattcgt
    11401 agaagctgtt atcatagcaa tgagagttgt tagtgataga cttgaatagc tcatcaccaa
    11461 cagaccaata ataagaggac taaccaagcc aatccctttt aatggaccag tccaaaacat
    11521 taccagattg tgggtagtat aatagctata ttgcttgtct tccatatgct gaatcatttc
    11581 taacacatgg tgagcaaaag cttcgttggc ttgattactc tgtatcgtgt ctgccccctt
    11641 agtaaaatcg gtgatactgg ctaggctttt ctccctcgcc tgactaagct ctaagcctcg
    11701 tgattgaagt aagtgattga acacaaactg tggaataatc atcaaaaagc caccaatagt
    11761 aaaggcaata ccaatataaa tatcctgcaa aagaaggtac aagacagagg ctaagataga
    11821 taggccaaaa acaggataaa tgaataaggg gaccaaatac tcctgccaaa acataggaat
    11881 atcttgggtc aaaaacgaat ttaaggctga agtaaaatag ttgagctgtt tatgataaaa
    11941 atgatataaa gccttctttg caataaggca attaaacgct ctaaccatag aacgtgctaa
    12001 aatgttatta agatacatgc acatataaat aaagacaaaa aaagctacgc ctccaagacc
    12061 aaaaagcaat accattcctt tattgttcat atcaatttgc cctgctatct gaattaatac
    12121 tgataacaat agtccctgca aggaatagag caaagccaat aaactataca agcaaagctg
    12181 ccattttgaa atgacttgta aaatactttt catatcaatc actcctcacc tgaaacctaa
    12241 atgtatcgct ctcttggaaa gtataaacga aacatcctca tacaccaatc atttccacca
    12301 caaactagat tcttgaatgt taaatcaagc tcttgatcaa aatcatgttc tctgatttct
    12361 tgaacaacca ttggttctct cctttcattc ttactatttc tagtatataa tgggaaaaaa
    12421 tacgaaagga aaaatttcgg aaatccggat atgaatatca gagagaaatt taaagcaatt
    12481 cgtaaacaaa gaagactatc cttaaaaacg cttggtaaaa tagctggctc agccactagt
    12541 atttctgact tcgaaaatgg aaaaacgaac ctttctaatg atgttttatt gcagctttta
    12601 ggctttatga ttgttgaaat aaacgagcta ttcgaatggg aggattttca cgaaaaggaa
    12661 ttggttgaag ccatcaagca aatcgaactg gcaataaaat ctaaacatat tcctgctcta
    12721 tctcagctac agcaggactt tcaaagctta tctaagacaa aggaacagta catttaccac
    12781 atcatctcac tgatcctaac catcaccatt gcagaatatc aaaacaaaga gatcgatcca
    12841 cacatcatgt ctgagctaac agactacttc tttttcttgg agtattggac taaccttgat
    12901 gtcggcctac taggaaacat cgtccactac atgacaacag atgccctaat cttattgaca
    12961 aatgacatct tagagcatac gcctcaagta ctccgaaata acctagatcg tattaggatc
    13021 gatactgtat taaactgtct tactgtcttg attaatcgta aagaggagaa ggcaagcaga
    13081 acacttctta aattattatt taacaaacat tatcctaatt actttgcctt tgaaaagctc
    13141 tatttacatg aattacaagc agtctatgat tttaactgga aagataaaga acaggcgctt
    13201 gcagctcatc acgtcatact ggctaccatt tcattactat ttacagctga tgaagccaaa
    13261 gaatgggaca gcttctttca agaaagtact agctctttgt aatactccag ctcatacact
    13321 aaagaaaagc aaggataatc acataaaaac taatcacatc actttgccct gctagctgaa
    13381 ttagcttggg tcatctctta tgcccagcaa aacatcatct agtctcagct ttcttccaaa
    13441 gcttcttgtc tctctgggct tgcaagcttt tgatagctta agaggcacaa gcattaacaa
    13501 aggctaacaa atgcctgtaa aaatatgcta tgataggggt aacaaaaacc taggaggtgc
    13561 ttatgtcaca caaatccatt catcaacagc ttagaaatgc tttttccttt cggacagcgg
    13621 tacgcgtcta caatgaccaa aaaatagcca aagaagactt agacctgatt ttagatgctg
    13681 cctggctcag tccttcctct atcggccttg aggcctggcg gtttgtcgtt ttagaaaacg
    13741 aagctgtcaa gcatgagcta aaggaggtct cttggggagc agtttatcag tttgagacag
    13801 ctagtcatat gatcctttta atcagcgaaa aaaacgccag atatgatggc gcttctatca
    13861 agcaaagctt attgcgcaga ggcattactg acgagcaagc cttggccagt cgtctggcat
    13921 gctacgaagc cttccaaaag catgatatga aaatagcaga tgatcctcgg gctctctttg
    13981 actggactgc caagcaaacc tatatcgcgc ttgctaatat gatgaccact gctgctttta
    14041 tggggattga ctcttgtccg attgagggct ttaactatga caaggtaaat gctatcttag
    14101 caaaacatgg gattatcaac cctgataccg agggtatctc tagcatgctg tctttaggct
    14161 atcgcctgcg cgatcccaaa cactcacaaa ccagaaagcc cagagaagag gttatttcct
    14221 tctttaacta agcccctttt gccattgctc ccaaagaaag tgcaaagaca gtcctttgcc
    14281 ttttcttttt cataactgtc gaattatggt acaatgtgtc aaaagaccta tggaaagtga
    14341 tgcctatgac attattatct gtaattatcc cctgcttcaa cgaagaagac acgattattc
    14401 cttatcttga agaaatgaag caaatcgaag cggccatgac cagccaatta gcctttgaat
    14461 atctttttat tgatgatggc tctacagatc aaaccctgag cgtgctaaga gagcttgcgg
    14521 ggcgcttctc taatgtgcat tacctctcct tttcacgaca ttttggcaag gaagctggac
    14581 tattagccgg cctagaagag gcaaaaggaa gctatattac ggtgatggac gttgacctcc
    14641 aggacccacc cgagcttctc ccgctgatgt atagcaaatt acaggagggc tttgatgtgg
    14701 ttgccacaag aagacagagc cgacaaggag agcctgctat ccgttccttt tttgctagac
    14761 tcttctacag attagtcaag catgtctcca acaccgaaat cgtcgatggg gtacgtgatt
    14821 atcgtttaat gacaagacag gtggtggata gtattttaga gttgggagag gtcaatcgct
    14881 tttccaaggg gattttttct tgggttggct acaatactgc ctatatcagc tttgacaatc
    14941 gtaagcggca gtacggcaaa accagctgga actttcttga gcttttgaac tactcgatag
    15001 acggctttat caatttttct gagatgccct taaccattgc tacctggact gggacactta
    15061 gctttttgct atctctgcta gccatttgct ttattgttat acgcaagctg ctttttggtg
    15121 atccggtttc aggctgggca agcactgtat ccattatgct atttatcggt ggaattcagc
    15181 tgttttgcat gggaatcatt ggaaaataca tttccaagat cttccttgaa accaagaaaa
    15241 gacccgtcta catcatcaaa gaaaagaaat aacagagcaa tcatcaaggc ccctatcagc
    15301 cgccaatgag gccgataagg actggttgcc ctcatcatga caagcacgac aaaaagactt
    15361 gatggtccca atcaaaacca tcaagtcttt tttagtatgt gaccttgcgt ctgcctcgca
    15421 cctaaaaaga cgagataatg tcataaccac cgtctatcta ctgaccccaa aaagttggac
    15481 aatttagttt taagcaaggg atttagttct gtattgcaca ggactaagca aggccatcag
    15541 cttgtaaaca gacgcttagc ggcggttcac actcttcatc acacgccgaa tgtcacgatc
    15601 ctgctcgcgt cgcttgatcg attcacgctt gtcataatca tgctttcctt tggcaaggcc
    15661 gattaacacc ttggcaaagc catccttaag ataaaccttt agaggaataa gggtcattcc
    15721 tgtgcccttt agctcatctg ctaggtgctg aatctcacgc tttttgagca ataatttgcg
    15781 cgtgcgctcc ggatcagcat tccagatatt tccctgctca aagggagcaa tatgaacatt
    15841 gaccaaccag gcctcaccat tcttgatttg ggcaaagccg tccttgagct ggatacgcgc
    15901 ggcacgaaca ctcttaatct ccgtaccggt caacacaatt ccagcctcaa ctgtctcaac
    15961 gatatgatag tcatgacgag cctttttgtg ttgcgctaat acattacctt caccttttgc
    16021 catgcttaac tccttttacg acctttcttt ttagcagctt tttggtaaaa tggtttcttt
    16081 gctttttttc ttgtcttctg ctttgatttt ggctttgagg gcttggactc cttactcctg
    16141 ctagcccttg aagcagcctt ttgcctgtgc ttatgcttag ctttagctga ccttgtggtc
    16201 ttttcaacca catcatagtc actagccaag taatcaaaat caatgtcacc tgtttccttg
    16261 tcagccctca ccaatctaac ccgaatcggc tgacctgctc taaatacctt tcctgagcgt
    16321 tcacccttta aggagagtgt ccgttcatta tagtgataat attcaggcaa attggtaata
    16381 tgcaccagac cttcaattgt atttggcaat tcgacaaaca tgccaaactt aaccacacta
    16441 gcaatcacgc catcaaacac atcaccaata taatctgcca tgtattctgc ttttttcatc
    16501 gcctcaacca cacgctccgc gtcaattgca cgacgctcta gctgagatga cgatactgcc
    16561 aattctggaa taacctgtgc aaaatgatcc accttctcct gcgtgatctg attgtattct
    16621 cgaatcatgc ggtgcaccag taaatcaggg taacgacgaa tcgggctggt aaaatgcgtg
    16681 tagtagtctg ctgctaagcc atagtgacca tgattatgct cagaatacct agcctgctgc
    16741 atagagcgca gcagcatcat attcaaaacc tctgctccag gacttccttc tacctttgcc
    16801 ataaaggcct gcaaggcttc ttgagaaatc ttattagcag ttccctgaat ctgaatccca
    16861 aaggcactag cgtaatcaat aaaggtctgc aatttctctg cctttggctc ctcatgaacc
    16921 cggtaaataa atggcaagcc agcccttgaa aaatgctcag caacacattc atttgccgct
    16981 agcataaagg actcaatcat gcgctctgca acacctcgct ggcgcaagac cacatcaacc
    17041 ggcatgccct tatcattgac aataatccta gcctcctgcg tgtcaaagtt caaggccccg
    17101 cgcttcacac gcatcgcctc taagatctga tgcagctcaa ccatagtact cacatcatca
    17161 gcaattctat caaattccct aagcgcctca ctgtcacctg caatcatctg attgaccgcg
    17221 ctgtaggtca ttctaaaggt tgtgttaatc actgactgac acagctgata atcaaccaca
    17281 tgtccctgat gatcaatctc catgatcgct gactgggtca accggtcaac ctttggattg
    17341 agagagcaga taccatttga caaccgctcc ggcagcattg gcaccacacg atctgtcacg
    17401 taaacagagg tcccgcgcgc agctgcctca cgatccaagg ctgacccttc cgtcacatag
    17461 taggacacat ctgcgatatg aaccccaagc tcaacgtttc cattggccaa tctcttgata
    17521 tggatggcgt catctaggtc tttagcatca gcaccatcaa tagtgatggt cgtttctttg
    17581 cgcaaatcaa cacgccccat aagatcctga tcactcggag catctggaat ggcattggcc
    17641 tcagctagaa cgtcatctgg aaacgccgat acaatatcca tagattccaa aacctccagc
    17701 acatcaatgc cgacatcatg ctgatgccca ataatatcac acacagtccc tacaaaataa
    17761 tcctgcccag ccttagggta ttgcacaata tcagccttaa tgatttcagt accatctaag
    17821 gcaattggag attttgcgat ataaatcctc tgttgaatcc tttgattttt cgacttgatg
    17881 tagccagcat acttagggtg atcatcatct aaaataaccc taccaacaac cgtctttaaa
    17941 gagcgctcca cgatagctac cacgcgagcc tctgctgctg tagccttaag ccgattagct
    18001 ggttttttaa taacagcctc aaccctatcg ccatcactag cataccccac atcatcacga
    18061 ccaataaaaa tgtcgtcctc attgtcatca accgacaaaa agccaaagcc agccttattg
    18121 gcacgaaaaa taccttgaac ccttatctct ggcttttttt gctgtggtgc tctaagaaac
    18181 acctcaccct catctgaaaa agacaaaagt cccttgcctt ccattttgga aatggcttta
    18241 atcaggcgag gaaagctcct cgcatcagtc atctctagtg cagccgccaa atcatgaata
    18301 tttgattggc catgctcctt taaataattc gtaatgttct ctatcatcat acctatcttc
    18361 tatttctaac accatacttg atggttgtgc tcattgataa aaaaatgagc tagactaact
    18421 ctgtcaagct cactccttat ttacttgata aaatggcaag cactaacgca attcctaacc
    18481 aaaaaaacac tagaactgct gtaaaacgtt gcataaaagc ttcaaatccg cgagcttttg
    18541 tacgctcaaa caaggcttct gagccactgc tatcaaaaac attgctacta ggattttttt
    18601 gtggctgcat aaagatagca atcacaagca acactgataa tactagcaat atcgtaagta
    18661 gtaagtcgta catgttaatt cctccactgt agtctcaatc attctaacac aaaaccaact
    18721 aagattcaac atgcagcgtt acttttctct ccttaggaca gtatttagga accttaatct
    18781 tctcagggtg acttgtttta tttttactag tcaaataatt tttgctgccg caatggctgc
    18841 actccaaatg aatctttact ctcacatcat ttccctaatc ttactatatt ttatcagcgt
    18901 cataaggctt caaatcaccc gcagcttctt tattaaagat atctctagtt attatagcat
    18961 attatccagt aagaaaacaa actcaggact tttagcaaaa aaggcttaag cgccaaccaa
    19021 taaacattcc aaggctatcg gggaatattt tctaatggtt attataaatc atgaacaatt
    19081 acctaacaaa gcaactccaa aacaaagata aaagacgaac attcaccttg ctgctcagct
    19141 atcaagataa acaatcctga tagcatcaat tttctttagg tcctcagcaa tcggttgtaa
    19201 tatcagacaa ttcaggtgtt gattaaaaaa aacgaaacta cggagaccaa ttgtcagaaa
    19261 gctattcaca gcccgcaggc gtcgtgctaa agtattgtct ggaaaaagaa aggtttagga
    19321 atgattatac ctaaactcaa aggagagaaa caatgagaaa aacaatgaag aagatgctag
    19381 cagcctcgac gctctgcatc atcatgtcag gcagcttcat cagcggctca gctagagtgt
    19441 tggcggagaa gtattatggt tttaatgatg gcacaggaga gcattcacca ttccctgtat
    19501 acgttactcc aattactaaa cctaatagga atactgccaa agttgtctac tgtttcaata
    19561 aagatatgaa gtggccagaa acttgggata aagcagcacc aaaaaaacca gataatttac
    19621 ctctatacta cgatatggaa ggtactgatc aattattcag tacatatgca agtggacaac
    19681 ttactcctaa tgtcagtaaa gtcttagcta atataatggc taaaggttat ccaaacaaca
    19741 atgagtttgc tcaccatttt aaactcactc ccaattccgc tgtaaaagtt actcaaatcg
    19801 cagtttggac tgttacggat aacctaaaaa actattctca atacagtcta accagagaag
    19861 aggaagctgc attaaattac ctaactgaca aaaatgggga cgactttagc gatagtatca
    19921 agttaaaatt atacattcca caaaatcctc gaactataaa atatcaaaat cttctaggtt
    19981 atgacctaat agttaaaact ccagaaaaaa aagataattg taaatgcacc aaaatttata
    20041 tagaagataa tggaaaagat ggctattatc tgtatattta ttatgacaac aatgaaaata
    20101 atagatatga ctcggacaaa gatagcctat tgcaaaagaa atacataaaa aatgggaaag
    20161 atgggaaacc aggaagacca ggggttccag gacttcctgg ccctgctgga cctcaagggc
    20221 ctagaggaga caaaggagaa accggggaac gtggacctaa aggtgaaaaa ggtctagacg
    20281 gtaagcctgg tgaaaagggt cctaaaggcg atacaggaaa agatggtaag gacggacaac
    20341 ccggacctca gggacctaag ggtgaccctg gacgtgatgg aaaagatggc gaacctggaa
    20401 aacctggcga gcgcggtgag aaaggacctc aaggcgaacg tggacctcaa ggacttcctg
    20461 ggcccaaagg tgagcctgga attccagggc ctaaggatga agatggaaaa gatggtgctc
    20521 ctggacatga cggacaaccg gggcctaaag gtgaaaaagg ggaccctggg caacaaggca
    20581 ttccaggacc taaaggggaa cctggacgtg atggtaaaga tggagaaaaa ggcgagcgtg
    20641 gagagcaagg acctcaaggc gaacgtggag agcaaggacc tcaaggcgaa cgtggagagc
    20701 aaggacctca aggcgaacgc ggggagcaag gacctcaagg cgaacgtggg gagcaaggac
    20761 ctcaaggcga acgcggagag caaggacctc aaggcgaacg cggagagcaa ggacctcaag
    20821 gcgaacgtgg agagcaagga cctcaaggcg aacgtgggga gcaaggacct cgtggagaaa
    20881 atcctactcc taccccagat ccaatgccac aaccagaacc acaaccagaa ccacaaccaa
    20941 tgcctgatcc agcacctaaa ccagaatcca agccagaacc taagccgata cctcaaccag
    21001 aggttaagcc tcagccagag acaaaacctc aacaaccaaa caagccatca accattacta
    21061 gccaatctag cggcaaatca ctgccaaaaa caaatgacac tggcagcttg atcacagcat
    21121 ttggtacagg cttactcact cttcttggac taggcttcct agcaaaacgc aaaagaaagc
    21181 aataattaaa acactaccca tagcctttta atcattggct atcaactaga taacaaaaag
    21241 cttatcgttt tactcctaac gataggcttt ttcgcattcc ctattgcttg gtctcaatac
    21301 tatttttcca gctttaggct ggttttgcta atccaaaata atatcagaca atttccgttt
    21361 taattaaaaa aaaaaaaacg aaactacgga cgccaattgt cagaaaatgg ttcacagctt
    21421 agagtcacca tgttaagcta ttctacgaag aagaaaggtt taggaatgac tatttctaaa
    21481 ctcaaaggag agaaacatga gaaaaacaat gaagaagatg ctggcagcct cgacagtctg
    21541 catcatcatg tcaggtagct ttatcggcgg atcagccaga atcctagccg agcagtatta
    21601 tgggtggaat gatggaacaa gagtaaaatc accttttttc ctttatgtta cgccaacaaa
    21661 tgaaacgact aggaaaaccg gaaaaaatgg tacaatagtc tattgtttca acagagataa
    21721 ggaatggcca gcaaattggg aagaaggaag atccttagaa ctagtgaatg ctgaaacagc
    21781 ttataaatta cccatctata ataaattact aggtacaact gattccttta ctaaaaatgc
    21841 tagtaaacca agagtatctg gagatattgg taaagcgcta atagctgtac tgaaaaatgg
    21901 ttatcctaat aaaaatttat ccggattaga tgacactaaa agtcgaatac taactcaact
    21961 agctatctgg tatttcagtg atagttataa taaagattat tttaaacaaa attatgaatt
    22021 aactgatcaa gaaaataact ctcttatgga gctgattaaa gtcggtgagg aagcagctca
    22081 aaaacaagaa aaaccagaat atcatttaga tatatatata actacagaaa aaaattatta
    22141 acataaacct tatcaaaacc tgcttggttc tactctaatt cctaaacttg accctaagcc
    22201 tgaaccagaa ccagatccta agcctaagcc agatcctgaa ccaatgccta aaccagagcc
    22261 taagcctgaa ccagagccta aacctgaacc taagcctgaa ccaatgcctg atccggcacc
    22321 taaaccagag cctaagcctg aaccaatgcc taaaccagag cctaagccag agacaaaacc
    22381 tcaaaaacca accaagccgt caaacgctac tagccaatct agtggcaaag cactaccaaa
    22441 aacaaatgac actggcagct tgatgactgc acttggtaca ggcttactct ctcttcttgg
    22501 actaggcttc ctggcaaaac gcaaaagaaa gcaataagct gaataagcta atgcaagaca
    22561 gcactagtat ataatgcgtg catggtccat ctaatgcagc acaaaagcct tatcgcacca
    22621 cgaatgggta cgataaggct ttttgcatac gctatagaag ctccaaaacc actagactag
    22681 ggcaacagca tggcaaggct tacgcctcta aatcatgcag agccttacta atctgtgtct
    22741 ctaaagcctg aaaatcacca gtattatcaa tcactaaatc agcataagct cttttctgag
    22801 acatcggcag ctggctagca atccgctgcc tagcagctag ctctgtcaat tgattacgct
    22861 tcatcaggcg cttgagctga gtctcctcat caacatagag cagccaaata gcgtcaaacc
    22921 aatcctgata gcccagctca actaaaagcg gtaaatccat aaagaaaata gcctctgttt
    22981 gagatagctc ctctttttgc ttggctaagg cttccctaat gatagcattc tgctgctggg
    23041 aagatttcgc catattttcc gaatgagcaa acagcagctc cgctagctta ggtctgtcta
    23101 attgccccga tggcaataaa atatcctgtc caaaggtctc tagtaggacc tgataaagct
    23161 tgccgccctt tttttgcagc tcatgcacca cctgatccgc atcaatcacc tggtagcctg
    23221 cttgtctgat aagtgcgaca gccgttgatt ttccggaggc aatacctcct gtaatgccaa
    23281 ttacctttgt cattgcttct gacacctagg acagacatgt gtccctcttc ctccaacctt
    23341 gagctttaca atggaggtcc cgcagcgctg acagggcttg cctgtttggc catagaccat
    23401 caaataatgc tgcatactac cattcattcc taaggtattc tgataggttc taaccgtcga
    23461 gccacccttt tcaataccta attgtaaaat acgaatcgtt tcatcatgaa tccgtttgat
    23521 ttctgccttt ttcaggctag cagatcgacg ctcagggtgt actctagctg cccatagcac
    23581 ctcgtccaca tagatatttc caagaccagc cactaaagtc tgatccaaaa gatgaggctt
    23641 aatggtcttt ttagaggcta gcagagcagc ctcaaaggtc ttcaattgaa aggtctgctt
    23701 cgtcggctca ggaccaagct gacgcttctg gaaaaaagca gccagctcag cctttggtag
    23761 caaatcaaag gttccaaact ttctcacatc ttggtaaacc agcgtggagc catcagtcat
    23821 tgtcaaaaag acatgaaaat gcttatgctc aggtaccgta tcaggaaaca agaggtattt
    23881 cccctccata cgcaaatgcg agatcataac cagctggcca aagtcaaaga gcaggtactt
    23941 cccgcgacga tctacccctt gcacctgctg cccagggatc gtcatcacaa aatgctcaag
    24001 gtctgttttg accatcttgg gcaccctaac tgtcactgct gcaatctgct tgccaacgac
    24061 taagcgctca agcccgcgtc gcactgtctc aacctcaggg agttcaggca taattaaaga
    24121 taccaaacgc gctaacaaag aaaccacata accaaaacca gcagaaccag ccagttttag
    24181 cactctttac tcagtctcaa tgttacaaac acgcttcctt tctataagct actattagaa
    24241 agccccaccc aaaacctcaa taagcttgag cacaaaggac tatcctttga taagaactgt
    24301 tatcattctt attttacgca taatccataa agaaagcaac tctcacgaac agcctttgca
    24361 gtcactgccg ctatagcatc agaaaagcac atctcgcccg ccaatccagc aagcaaagac
    24421 aaagcccctg agctagccta ttgtttgcca gcccaagggc acgttgtggc ctttagtgtc
    24481 tgtaaataga aaaccaagca atgctgcaag cctcaactga caatgctagg tctgatcagt
    24541 cctgtcatca gcttgcggat aatctatact aattggccta tcaacaagac ggatactatc
    24601 ctggtaaaca ccttctgttt caaaaataac aatgtcattt aatcccttgt tgaaatagcc
    24661 ctttggaata taaagggtta ataagggacc cacttcccaa aaacgaccaa tagggtgatt
    24721 gttgataaag acacaaccct tcccaaagcc agtcatatca atatagcttg cctcaggctc
    24781 atgacattca aattgataat gataaaagcc gggctgcccc tcgtaaaaat cgccatcaaa
    24841 acaaagctga gacaaatcat caagcggcag acaatacatc tcccaattgg tcacaaagtg
    24901 caagtcagcc atcataccac gtcctagacc cttactttga ctaggtgctg tcagcttgtg
    24961 cccataattg acccggccca tattttcaat taaaacatcg acctgactca aggcatgctg
    25021 ctggttaatg atgatatcat caccaatcgt ctcctgatac tgtgttgcaa ccttttgacc
    25081 atctaaaaag acctgtgctc tatctctact atcaatcaag cgtaaacgct cgtcctcacg
    25141 cttatccttc aaaagatgtg tccgatacag gatatagccc gttgattgcc ctaaagcctc
    25201 tatgttacta ggatagcaag cagtctgaca gctgctgatg tgctccagcg tgctaaacag
    25261 actaaccttg tccttcagac caatcagagg cagtgacatc aagggcttaa tcaagggagg
    25321 agtaacctct atctctgaaa gctccgcggt cagacgcttt tgaatcgcgt aaaacttagc
    25381 tgtcggattg ccagcctcat ctaggatagc gtcataatca taggaggtca cctgcggaag
    25441 gtccaattgc tttctggcag agcagccatt cataaaccca aagtttgttc ccccatgaaa
    25501 catatacagg ttaatactgc cctgcgccaa aacctccatc actgcgtcag ctcgctcttc
    25561 agggtcgcgt ttgatgatgg gctcatgcca acgattgaac cagccgtccc aaaattccat
    25621 acacattaaa ggccaatgct tgccatgctc agaaaagaag gcctgcatgt cagcaaaatt
    25681 ctcctgtgcc cttgagccaa agttgccagt cacaaagaca tcatcttcaa tcagactacc
    25741 agctctaaga gtggctcgcc aaggaccatc tgctgtaaac aagggcgcac tgaggtgctc
    25801 ctccataaag cccttaacag ctgttaaata ggccttatcc tctccatagg agccatattc
    25861 attttcaagc tgaaacatca aaatattgcc gccctgctgc cattcatgcc ttgctagtct
    25921 cggcagcagc tcctcataat agcgcctcac ataggctaaa tagacaggat cagacgacct
    25981 gatatgacaa ttctttgtca gcagccaagc aggtaggcca ccaaattccc attctgcaca
    26041 aatataagga ctaggtctga caatagcata gagccccaat tgctgcgcca gcgtcaaaaa
    26101 ggcttccaca tctaattggc cagagaaatc atagctttcc tccctagcct catgtaaatt
    26161 ccaagggaca taggtctcaa ccgtattaaa tcccagtgcc tttaaattat aaagcgaatg
    26221 ataccaatca tctgggtgaa ttctaaaata atggatagcc cctgacagga tttgcagcga
    26281 tctaccatct aaataaaact gatctgaaat ctgaaaacgt tccaagctta attcctcact
    26341 tattattgct attagcctac taggcctcat tgctgagcgg cttggaatgg cccattctag
    26401 caacagcgaa caggccattc agcagacagg ctaacttatc ttatggtaac aattgtaaac
    26461 actatctaca gtctgactcc tcatgctatg ctgtcacagc agcaggataa gagacagtgt
    26521 atgccttgtc atctgtcaat ctaatcccat atttggtttc aacaatagta tggtcaaact
    26581 gcggtaaaac agttatcggt ccttcaggca tactctccag agacaattca aatatcgctg
    26641 tgtctgtgcc atctcctgaa acatagctgg caagcttatc tacgccattt acagtaactg
    26701 ctaactgacg atcaccaaga ataaacatcg gttgattaaa ggtcatctga atggttatgc
    26761 ttactttgcc attttgcttt ggagctgctg acgttattgt tacttcttca atttcagcct
    26821 tatcctcacg aaactggtct gagatcatct gcttgatatt aaaggttgaa taggtgatct
    26881 gaccactata ttcgtataac aaaccaaccc tctcgtcgtc tagttgaacc aagctagagt
    26941 aagcaaaacg ctttggctca aaaatggttg aagcgaccca atgaatgcta tcgtcctcta
    27001 agacctcacc gacacgcaga atccctttca tgcgctgatt tctaatcgtc agttgctcac
    27061 ctgagggctc tcctaaagga ttggataaaa caacatattc tttgccatca accatcatat
    27121 gaatagctga caaattgaca taaggctctg ggaggtctgt gattgtagga ttatcgtccc
    27181 aagtcatacc atagtctgtg cttctggcaa taacgattgt ctttccggta ttgcgcataa
    27241 actgtaataa gtgaccattg tttagctgaa tgatttgatt ttctgtcaat tctgtgactg
    27301 atgtatcaaa atccttagag gttgtttgtt ggttatgacc ataaattctg ccatcatttg
    27361 gtgattcacc tcgttgccat gtttgaccgc catcatcact aaaaatatta gcactgcttt
    27421 gacgacctag actagctgat gtcgcatttt gttgattggt atagtaaatc gggaaaacta
    27481 accgtttcac ctgctcaccc tctgcattga ctgcgtctat ttcaatgcca gctgcggcac
    27541 ccgtacctaa aaatcccatc cagtcttctt ttatttgtgg ggtaatatca agaggtgtgg
    27601 accaggtttg cccttcgtct tcactggtta gcagccataa aaagctggtc atgtaagtaa
    27661 atagaggagc tgtttgtgag ccttctctag tgatgccttg cttagtgcga ccacttctca
    27721 gataaatatt ccctagtaga atatcctctc ctgcctctgt ttgatagagg ttgccgcgtg
    27781 tgctaaaggc tgtctcaaaa ttgccctcat caacatacat atctgtctga tggccactct
    27841 ggtcatagac gataccacct tcacgcacag tgtatttatt attgtcaaaa tcataaagat
    27901 ttaaataata ctgaccgtta atcaattcat atcctgagcc tgctttagaa gcaacagcac
    27961 cctgtgactc aggaaagaca tctaccagca aataaagctt gccagaagcg tctgttagca
    28021 aggtggagtc tattgaaaaa gcagattgag tcatgttggt attccaatca gccaagctat
    28081 attgtgttgt aaaataaggc tgagttggca tatctaagac cgtaatgtta ttactccagg
    28141 ttttgccatc atcatggctt atcctgacaa cagttgcaac atctccccag tcattgtagt
    28201 gcttctttct tgcatctgct gcggctatca aggttcctga tggcgttttg acaacagagg
    28261 gaatccgata ttcaaagacc ccttcatcat atttgtccca aacattcgtc ttttcaccag
    28321 taactggtcg aagggttggc tgatgagcct tggcaatatc tgtcagatca tacacatctg
    28381 tatcaatcag cacctgatca accagtccct ttaaccccca gtgaaggacc gactcaccat
    28441 cataggtgcg tttcaagcct ccaattgtta gcgtatcagc agaagccttc caaggtaatt
    28501 gcttcataaa cccagcaaag tcagcttccc catataagtc accattcaag taaatcttta
    28561 gcctagaccc tgtaaagaca tagctgatcg tctgccagtc cgagttcgtt aataaattaa
    28621 agcctgagcc aacttttaca atcggaacct cagctccttt aaattcaaga cctattttat
    28681 tgtttttagg ctcgataaag aaagaggcgt attcattagc tgatgcttga tttgagatcg
    28741 ataacaaggc caagggcgat gagcttctca ctgttgtatc agcagtatct agacggtatc
    28801 tgattgttac agttccttgg gttaggttca tcacatcgtc tagcttacca agagcctcgt
    28861 catctgttac ggctgctttt tctgctgttg cgtccaaaat agcattgcct aaatcaacta
    28921 aaatggatgc ttgatctgag attggctgat ctgagatata gcttgcttct atgcttgtat
    28981 aaacagctcg tccgccttct gtggtgtatt tgatctgata atgctctgca cttcccaaga
    29041 tctcctctgg cgtaacccat tgccaattgg ctggcagggc tactgtagat aagggttctc
    29101 ccttcttacc aatcagacct tctttaggta atacagttaa aatagctact tctcttgcaa
    29161 tcttagcagt tggtgttact gttgagccta aatcagcatt gtaaggaaca gcactatagt
    29221 aaatgttata aataccagga gctagctcag acaaggctga caaatcatct cgaccagcag
    29281 cctgtaaagc agcattggta tttccaccct tgttagtaaa caagtattca ttttcaactg
    29341 aaaaatcaac cacatagcct tcctgatcag tggttacagc ttgagctaaa tcaggactgg
    29401 ttccctctag catggtcaaa tccttgaccc ccttgagaac tggctgtgag gcataataag
    29461 cttctgaggc tgctttttgc tcagcatctt ggtaataacg cacataatca atcacaaagg
    29521 ccgtctcatc tgaagctaga tagtagcctg catttttact ccaattgcct ccagtagcaa
    29581 ggttaaactg aaggtattga ggcttattaa aggcagctgc ggcagcctct aagcgatcat
    29641 caccggttaa atacatggta ttataaacaa tcccatcaac ataccattca atcttatccg
    29701 gataccaatt aataccaaag atatggtagt catcataaaa gtcatcactt aatgtcagat
    29761 tgccacccaa tgctgttggg ctatagcttc catctttgtc tgcatcaccc ttgatatagt
    29821 aaaaatgagg ggtcccgtaa actgttttgt tgctttgatc accttcggca agctcaccct
    29881 catgctctcc gttaggagca ccgattagct ccataatgtc aagctcacct gtgcttggcc
    29941 agccatagcc ttgagttgac gcaatatcac catctaaggt aaaatcagcc cccaatgtcc
    30001 aaaaggctgg aaaggctccc ttacccttgg gaagcttggc cctagcttcg atacgaccat
    30061 ataaaaattc ttgcttgcca accgttcgta cgcttcctga atcataaatg acctgacgtg
    30121 cgcttgttcc tcctctagga ttggcataac ggtcctcccc ataacgctct gtgacgttta
    30181 aaacaagatt gccattatca agatagacat tctctgtgct gtctgtgtag tgctgctgct
    30241 cattcccgcg aatacttccc aattcatatc cccagttctc ttggtttaac cgatctcctg
    30301 aaaactcatc ctgccaaatc aattcataat cattttcctc tacgacactc acgttatcaa
    30361 tactagcaga ggcagccaag gcttccggag aagaggcttc caaccatttg actaagccaa
    30421 caaaggtttc tgaagtcgtt gctgtaaagg agagcttgat atgtgaccaa gtaccgtctg
    30481 tatctgtgag gctgacctct ttgataacag ggccctgaag attgtgattg gactctttag
    30541 cggtaaggta taagccatta tgaggtgtgt cagcttcaac cttcacatca gcctctagcg
    30601 tataggtttt cccaaccgtt gtagacacct tttgaaggat atgctcatct aaagtgccgc
    30661 ttgttacctc agcatagcta ttaccattct ctgttgtgag gactgaatga cctccctctc
    30721 tatattgcca ctgattctta ttggacacat aatcattgtc aaaaccacca ttagccacct
    30781 tattgagctc aatcggagcg ttagacttct cttcgtctgc tgtctgatca gcagcattgc
    30841 tggtcacagc attagctact actgcctcat ctactgtcgt ctcctctgag actactaagg
    30901 cctcgctatc tgtatctgta gcttgaggct cctgctcatg gcttatctct gttactgctg
    30961 ctttcgtagg ctgctgcagg cttacctctg aaacgtcatc agcataaaca gccactggca
    31021 gaccagcagc aagaccaata cccacacaca ctgaagcaac accgacacta agctttttga
    31081 tggcatattt tctaatttgc tcttttccga taggattaaa taacatgttt atttcctcac
    31141 ttatatatac atcattttta aacacaatag cttttcaaag gcccatttag cctaatccag
    31201 tgctggtcag gctaacgacc ttgttataaa aacgctttca attcagcgct taaaagaaga
    31261 tataccagat gaaaccgata tatcctctca caaagtgact aacctgcctt ttcaagctca
    31321 ttatcagcca tcttaacaaa tggaaggtaa atcaggtttg ccaaggccaa attgacaagc
    31381 gatagcacaa tagcacgcca atcaaaacca gttgaaaaga agccatacaa gacaggcggc
    31441 attacccagg tcacattttg cgtaacgggt gcaaccaagc ccagactagt tgcgatataa
    31501 gcaacacttg acataacagc aggacaaaca ataaacggaa taaacaacaa aggatttaaa
    31561 acagttggta aaccatacat cactggctct cctatattaa acaatacagg agcaacacct
    31621 agcttagcca cctcacgata gtgttcattt ttagacttcc agaaaatagc aatcaagagc
    31681 cctaaggttg cataccatac aaagaacact cgtccaaaga taaggaatcg cctcatgctt
    31741 ttgataagcc tccaaattag ccaagagggc aacaccaaat actccctcca tatttggcgc
    31801 cataacattg ccgccatgaa tcccaaagaa ccagaaaaat tgggtcaaaa cagctaccaa
    31861 aacaacagca ataaagcttt gtgataagcc caaaagtggg atttgcaaga ccttatagat
    31921 ccaatcaatc atcaaagaac ccgttagctt ttcaaagaca aatgttaaaa tagctacgct
    31981 atacaaggcg caaaagcctg gtatgataga taagaagggc ttggctacag caggtggcac
    32041 actatctggt aatttaattg tccaattttt taacattaat ttacaaaaaa taatagaggc
    32101 taaaaagcca atcataattg ctgtaaaata accattggag ttaatttgcg caccaggcaa
    32161 taggcctgag atggtcacat taagtgagct gccgctgaca gtaacaccac tgtccttaaa
    32221 agccgtcaca agatcaacac ccttgagacc tgacgcgtca atgctagagg taacagaatc
    32281 cccaatcgca atcacaaagg cagctaaaga aaccaaacct gatgagagcg tatctgtctt
    32341 ataaagttta gcgacattaa cccctaagca atacacaaat agcaaggaca caatcgaaat
    32401 gcttccctta aagacaaggt tgttgatggt tacccaccat tggaaggcct ctgtaatgcc
    32461 ttgcaagcca aattggtctg gaatatccac taaaaaggca ttgatcaaca gggcaataga
    32521 gcctgtcatc acaaccggca tcgttgcaat aaaagaatct cgcaaggcca ctaaaaatcg
    32581 ttgattacca atcttcgtag caattggcag cagcttttgc gaaagaaagt tcatatagtt
    32641 attcattcat agctccttaa aacaatcata aaacagctaa gatagagcag taaaggctct
    32701 ctctaacagc ttagccttca tttttagttt gctcgctcgc ctgccatctt ctttccacat
    32761 taataataaa cggcaagtaa agaagaatat ctagaataat taaaacaagc tgtaggactg
    32821 aggcttgcca gctgcccgtt gccaaaaatc ctgaaataac aggcggcatg gtccaccccg
    32881 gatcagcata ggtgccaggt acaatgccag aagcaaaggc aaaataagcg acaaacaaat
    32941 tcataacagg tgctagtaca aaaggaataa ctgtcaatag atttaaaaca accggtaagc
    33001 caaacatggt cggctcgtta atgttgaaaa accctggaat caaggtcaat ggtgacaaga
    33061 cctttgcctg ctgactagcc ttgcgacgac gtgctaacca ggctaaagcc aacaccaagc
    33121 caatggttgc accagctccg ccgataaaaa caaagttatc cataaagaca gacgtaaaga
    33181 catgcggcaa ttcctgacca gccttatgag ctgccatatt ttcagtcaag ttagataacc
    33241 agatcggctt cataatagga ttgtttagga catttccacc atgcacacca cagaaccata
    33301 aaaagccatt aagaagaaca acgataaaat taccaaataa ggtacttccc agcaagccaa
    33361 atggaactcc tagtacggac ttaacaatgt catggacatt tggcaggcta aaatgatcca
    33421 agaaagcata aacagcaagc caaaacacaa taatcaccgc tccaggaata atggcgctaa
    33481 agctttttga tactgcaggc ggcacaccct caggcatctt aatccgaata tcctttttca
    33541 taaaccattg ataagcatag ccatttacca atcccaaaac aatggcaaca aacaagccgc
    33601 ctgatgaaag gtaagaaggc gcaatacccg ctacctcacc caaggcttta ccagattcat
    33661 tgacaaatga aacagtaaat ggggtcactg ttaaaaaggc agagatatta ataatcccag
    33721 cagaaatccc gtctgcctta tactgcttag ccaagctata agaaatccca aaggccgcaa
    33781 ccaaggcaat cagattaaag ctcgaatcta ctcccttcca cagataggta gagacaccaa
    33841 tctcaccaag ccaagcttcc caaccaggaa tcggcaggct agcaatcacc attaaaaagg
    33901 acccaatcaa aatcaagggc atagcgtagg tgatcccatc acgaatagca ataagaaagc
    33961 gattgcttcc taggcgacca gcaactggaa caagcttttg ctggataaaa tcttcaaatt
    34021 tagtcattgt tacctccttg tgacgttaac ctttcataaa tagatactag ctcccttgcc
    34081 aaatcaacaa aggtaatact agtcatcaaa tgatcctgac catgaactaa tagtaggctt
    34141 actggtgtag catttccccg tgcctcttga gttagcatat ctgtttgtgc atgatgggcc
    34201 tgcaccaatg ccttatcggc ctgctttaga ctttcctgag cttgattgag ctctcccttt
    34261 ttagcaaaag caatcgcctc catcgcaagc gacttggcac taccaccatg catgatcagg
    34321 cccataatcg tctctagctg cttatcttcc atgaccacca cctatttcat caaactttca
    34381 gctaaggcaa taaccttatc accattcatc ataccgtaat caaccattgg cacaaccgcc
    34441 actggaatgt ccttttctgc caagctttct tgaaatgctg acaattgata agcaacctgt
    34501 ggccctaata acaccacatc aacaggatgg cttagagcgt aatcctctgc ctcagtcaat
    34561 ggcaatgcaa aaatatctgc ctcaagcccc cgattgtcag cagccttttc catctttgtc
    34621 actaatagac tggtactcat acccgctgca caggccaaca taatttgttt tttactcatg
    34681 atcttctcct ttatcccaaa tcctaacgtc gaatagagcg cgacattctc acaatggtat
    34741 gtctttttcc tcggatagcg tcactaagag caaagatatt ttccactggc gcaatcccgc
    34801 tatagccagc atctccgata tgatgaatat cgacaccaca gattttattg cgaatagcaa
    34861 tgtctcgaac gatcgtagta tctgaccctt cctgactcgt tccaatagct gacataacta
    34921 gagcatcgtg agcatgcacc tcctcaacaa tagctctaag gtcaccctct gtaaagccag
    34981 gaactgtccc aacagcagga actaaaatca catcagcccc agcctcgata aaccgccgaa
    35041 cagtttctaa gtcaatcacc gcttcattag agccagcagc atgcatcttt ccagcaataa
    35101 tcaagcctga aaaatagtgc ttggcctgtt gaatagctct ttcaatctga ttattgctaa
    35161 caccagtacc tggatttcct gtcaagcaaa caaagtcaaa gcccaaggct tcaatctctt
    35221 gaaaggtctt agctgtcgcc tgtcgccctt ctactagctc caagcgcttt tcagtcatgt
    35281 caacgtccaa atcaattggt tctaaattaa caccaattgg acgccccacc agacgacgca
    35341 gctctaaaat aggctgatca gtagcaggta gaccagatat ttgaacatca aagacatcta
    35401 cacaattcag caaaatcaaa tcagcactaa aggctgcggc aacctcagcg ttcgtaaggt
    35461 catctccagt ccaagagggt cttggcgcta cattttctga gacaatggta cgtccctcgc
    35521 ttgccttaat ggcttgcttt agctctaacg atgttaactg tagcatttct gagctactag
    35581 cactcaataa tcgtgttttc atcgcttctc ctttattttt attttaaaaa cattaacaaa
    35641 agataaataa gatttaactc ttatttgttt actttttata aacaaataaa gtatattcta
    35701 tttaccaata tttgtcaacg ttttcaggca ggatttttaa ttcttttttg gtatgataga
    35761 ggtacgataa tagaggttac tatgaagacg gataaacaac aagagcttta cgcaaaaatt
    35821 ttagatacca tttatgccca acggcctatt tcacgcattg atatttcaaa gctaacgcac
    35881 atcacacctg ctacagtagg ggctatcact aaagagctgc tagcacaggg gtggatacac
    35941 gaaatcggag agctgacgga ccactccgtt ggccgcaaaa aaatattact tgatgcttcg
    36001 gctaacgcct tttattttgc tggtgtcgaa ttgtccgaaa agcatttcta tttggtcatt
    36061 acagataacc tgggcaccat ctatgccaag cacaaccaac agatcgaccc aagcatttcc
    36121 tcctactaca aagcagacta tatctctgag ctgattcaag ccttcctcaa gcagcacaag
    36181 cactatgatg tacaagccat aggaatagca ctgcctgggc attacgatca ttccacctcc
    36241 agctcaacgc atattaacac caacaatccc atctggcagc aggtcgattt aaccgcaatt
    36301 gcgaagtcct tccctattcc agtggtcttt agcaacaatg ctcactgtat gattattgcc
    36361 aagcgcttat acgagcgtca ggcacataat cacaatttta ttttctttca tgtcggacga
    36421 ggcatgcact gctcctatat gtataagggg gtcatttata gccgtcacaa tgctgttgtt
    36481 ggggaaatcg gacataccat tgtcaacccc actggagagc tttgtgaatg tggcaaaaaa
    36541 ggctgtttac agacctatgc cagcaatgcc tggttgctca aaaaagcaaa actgctacat
    36601 cagtatgccc ccaattctca tctaagaagc cttgtcgata aggcctgtga gctcaagcta
    36661 gaccatctct tgattgccta tgagcttggt gatgtcgggg tgaccacgct cattcacaca
    36721 gctattgatt accttgtttt atccctgtct aacctctcct tactgattga taccgagcaa
    36781 atctatctcc atggcagatt tatcagccat cctcttatat cctccaaaat tctgcaagcc
    36841 ctgcaaaatg acattaagct tcttagcaat caaaaaaagc cagaaatcat tgtcatgcct
    36901 ttttctgtct ataatgccgc tgtgggagct acaggcttat gtatagatga gctttacctc
    36961 aattataaaa acaaatatga ttgataaccc ccacaccaat atcagctaaa gctttaaagc
    37021 ccatttgaga agctatttct caagtgggct tttgcattat gcgactttca gtccatctcg
    37081 ctccgcaggt gcgagacaaa tgataaccat aaaaaaagag aggcacttgg ttctctctgt
    37141 tctatcctaa tgccccattt gaaactcacc agcaaaatac tctgccagca tcagtctatg
    37201 cttgtctgag attgaagaca gctctgcaat ctcttctcta gaaaaataac cgagccttaa
    37261 ggtttcatca ttttgataat cagtgatagc cttatctgcc ttggctataa cctcataaag
    37321 catcacaacg gtctgaacct tatcaccatt tggataggtc tcttcaaaat tggtataaac
    37381 attcaacaac cgtaaaggct ctactgtaat ccccgtctcc tcataaaatt cacgcctgca
    37441 ggtttcagca gaagactcac ccagctccat ggcacctccc ggaattgccc aggttttctt
    37501 atctgcacgt agctgcaaaa gcaccttacc ttcggcattg gccaaaatac caccagcaaa
    37561 agtcagaata atgttatcat gccccacctt tgagcgaata taggaaatat agtcctgtgt
    37621 catcgtaact cccttcattg ccatcataag attaaagcca gtcagctggc gcaattgctg
    37681 cttttttgcc aaccaataag caatgcaggc tttgtctctt gtccttgata ggctggcaaa
    37741 gcatatagcc ctaatttttc aacctgatta tatcacactt tttaaaagcc agaaagagac
    37801 tcgaatgcca agtccctttt ctttcaatct ataaccaacc tcagaaaaac tcagacaagc
    37861 tacgataact tttttaatgt cttctttggc caatggtttg cgactggtca ttgaattact
    37921 ttcaatatta tccccatcat cacatgataa ccacaaataa acacgtactt gtgtcattgc
    37981 cttctcctca atcagtagta ggtacctact gtttttttga ttgattgtac ctataggtgt
    38041 ttttttcctt caaaatcttt aaataaaata ccctttataa
//
LOCUS       DARYYD010000019        35713 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.019, whole genome shotgun sequence.
ACCESSION   DARYYD010000019 DARYYD010000000
VERSION     DARYYD010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35713
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.019"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..693
                     /locus_tag="TV188_000844"
     CDS             <1..693
                     /locus_tag="TV188_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534218.1"
                     /translation="TDDSFIAVFDPKLKEIDKHIFEDSVIASDFSVDGDDIYLLGTDV
                     KIKDNYPTYLYTLSIKNGQLAMKNKELLYEQPESTYFFHDSIVKEKQLYTALSGYRNN
                     VTKERTVLGQVFHYDMQSGQKHFFDLTEIAPVNIFDLGHDTLAIEHEKNEAGKIGFSL
                     FHLNDKTSTFIDLSQFGLSIESDYLKDVKQIDENTLLILAGHTLIGYHINDHQAIFNK
                     QVSDDAFHIWVK"
     gene            complement(1204..2832)
                     /locus_tag="TV188_000845"
     CDS             complement(1204..2832)
                     /locus_tag="TV188_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1534219.1"
                     /translation="MNWSTIWELVKINILYSNPQSLTALKKKQEKAPKENFKAYKSMI
                     RQQALMIALFLVIYIFMFMGVDFSQYPGLLSLYIAIFFVMATVNAFTAMYAVFYESND
                     VKLYVHLPIRSEELFIAKLISSLGMGSIFLMPLLSLFVIAYWQIIGNALAIVLAFILF
                     VVLFVSSIVFALYLNAWIGRIILRSSKRRLISAVLMFASTFGALGLIVFLNMTNNQRM
                     MADQAFSDRPLIPYFRGSYDVVVAPFSSQALLNFWLPLLLVMLMLYGLVRRIMPAYYR
                     ETLYVGGKAKNAAVARKAAASDRQQSLQRLLTKHHLATLQNATLLTQTYLMPLIYVMI
                     FITPSVTSGAQFSSYITDEYFGIALLVGVLLGSICTVPTSFVGVGISLEKDNFTFIKT
                     LPISLKGFLLNKFRLLIGLQILAPLVVYALIGLFVLGFHPVIVLSFSLGFVLMGIIQG
                     QLMFRRDYRMLDLKWQDVTQLFTRGNSQWFMLGLMFGDLIVGGFLIVLAIMCATISQQ
                     PLLVSIAVSLILLSCLLFAQLWIQRSFWKNLNKM"
     gene            complement(2837..3568)
                     /locus_tag="TV188_000846"
     CDS             complement(2837..3568)
                     /locus_tag="TV188_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534220.1"
                     /translation="MIEFRHVSKLYGDKEALSDVSLTIKDGEIFGLIGHNGAGKTTTI
                     SILTSIIEASYREVLVNGQLLSEHRNTIKRQIGYVPDSPDIFLNLTAYEYWQFLAKIY
                     GVSEADTKARIEELTQLFELTQEMHNTIDNFSHGMRQKVIVIGALISNPSIWILDEPL
                     TGLDPQASFDLKEMMKEHAASGNTVLFSTHVLSVAEQLCDRIGILKKGKLIFVGTVEQ
                     LKADYPDKDLETIYLELAGRQAQEA"
     gene            complement(3605..3862)
                     /locus_tag="TV188_000847"
     CDS             complement(3605..3862)
                     /locus_tag="TV188_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1534221.1"
                     /translation="MEKEQQRLYDVIKQAYDYPENRANSHLARLLLSASNQLIKNSNP
                     LTIAEQLNQALDDYLQANDLLLPKSLCGFKQSLDAYLLEKG"
     gene            4233..5681
                     /locus_tag="TV188_000848"
     CDS             4233..5681
                     /locus_tag="TV188_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1534222.1"
                     /translation="MINKRKKKLIYRYGVCSAAVILAALASLGTCKEAKALSGPPGYP
                     LTRDFSRNFLEENTAKYLDQLREHLQHRFSELESLTRKLEKEGGTRGPAGPPGPAGPK
                     GERGEPGPVGPMGPRGEQGPKGLDGARGPEGQQGKPGPVGPQGPAGPAGQKGETGPQG
                     PRGDKGDTGETGKQGPAGERGPAGPQGPRGDKGENGAPGEQGPIGPKGETGPKGDKGE
                     RGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGQRGEKGEQGPRGEK
                     GEQGPRGEKGDQGQRGEKGDQGQRGEKGEQGQRGEKGEQGPRGEKGEQGPRGEKGEQG
                     QRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGDQGQRGEKGEQGQRGENGEQQPKGD
                     QGKDTKPSVPKAPESPKMPEKPQAPEKAPAPKAPKASEQSASPKAPAPQSTPSKKAVL
                     PATGEASHPFFSLAALSVIASAGLLTLKRKKS"
     gene            complement(5863..7851)
                     /gene="tkt"
                     /locus_tag="TV188_000849"
     CDS             complement(5863..7851)
                     /gene="tkt"
                     /locus_tag="TV188_000849"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEL1534223.1"
                     /translation="MTFDAIDQLAVNTVRTLSMDAIQAANSGHPGLPMGAAPMAYVLW
                     NHVMTVNPKTSRRWSNRDRFILSAGHGSAMLYSLLHLAGYDVSIEDLKNFRQWGSKTP
                     GHPEVNHTDGVEATTGPLGQGVANAVGMAMAEAHLAAKFNRPGFDIVDHYTYALNGDG
                     DLMEGVSQEAASLAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHIL
                     VKDGNDLEAIAKAIEEAKAETEKPTIIEVKTIIGFGAEKQGTSAVHGAPLGAEGIAFA
                     KKSYQWTHADFEVPQEVTERFRQGLQARGEQAEQAWNDLFAAYEAAYPELAAEYKKAF
                     ANEAAEVELQAHELGTAVASRVSSQQAIQQISEQVPAFWGGSADLSASNNTMVKAETD
                     FQPGHYAGRNIWFGVREFAMAAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQQ
                     LPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPADGNETNAAWKRAIAET
                     DRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGIIIATGSEVKLAMDT
                     QAALAADGIHVRVVSMPSQNIFDEQPASYKEEILPAAVTKRLAIEAGSSFGWAKYVGL
                     AGKTLTIDTWGASAPGNRIFEEYGFTVEHATELYKSLS"
     gene            complement(8235..8879)
                     /gene="fsa"
                     /locus_tag="TV188_000850"
     CDS             complement(8235..8879)
                     /gene="fsa"
                     /locus_tag="TV188_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1534224.1"
                     /translation="MKFFLDTANVEAIRAINELGVVDGVTTNPSIISREGRDFETVIK
                     EICEIVDGPISAEVTGLTAEEMIAEARNIAKWHDNVVVKIPMTTEGLKATNVLSQEGI
                     KTNVTLIFTVSQGLMAMKAGATYISPFIGRLEDIGADPYQLISDLRGIIDLYGFQAEI
                     IAASIRTAAHVEAVAQLGAHIATIPDPLFAKMTEHPLTTNGLKTFMEDWASFKK"
     gene            complement(9053..10558)
                     /gene="glpK"
                     /locus_tag="TV188_000851"
     CDS             complement(9053..10558)
                     /gene="glpK"
                     /locus_tag="TV188_000851"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEL1534225.1"
                     /translation="MGTETYIMAIDQGTTSSRAIIFNKKGEALVSSQKEFPQLFPQAG
                     WVEHNANHIWNLVQSVIADAFIESGIKPEQIEAIGITNQRETTVVWDKQTGLPIYNAI
                     VWQSRQTASIAEQLKRDGYTKMIHEKTGLVIDAYFSATKLRWLLDHVPGAQERAERGE
                     LLFGTIDTWLVWKLTDGAVHVTDYSNAARTMLYNIKELKWDDEILALLNIPKAMLPEV
                     RSNSEIYGKTASFHFYGGEVAIAGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GQEAQLSSSNLLTTIGYGINGKVYYALEGSIFIAGSAVQWLRDGLRMIKTSFESEQLA
                     LASTNADEVYVVPAFTGLGAPYWDSNARGSVFGLTRGTTKEDFVKATLQSIAYQVRDV
                     IDTMQVDSGITIQQLRVDGGAAMNNMLMQFQADILGIDIARAENLETTALGAAFLAGL
                     AVGYWKDMETLKQLNATGQLFKASMSESRREKLYQGWKRAVKATQFFAEEL"
     gene            complement(10898..11491)
                     /locus_tag="TV188_000852"
     CDS             complement(10898..11491)
                     /locus_tag="TV188_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HEL1534226.1"
                     /translation="MIIKKLSVIALTSLSLISLSACRQQNQALGQNGSAQNHRKASVS
                     EDKAKELAFKDASITAADAQRLKLTKETDDGRVVYDIEFDAKDQEYSYTIDANTGEIL
                     EKSSEPITEAPASAQAAGGQADQAAGISEDKAKELAFKDASITAADAQRLKLTKETDD
                     GRVVYDIEFDAKDQEYSYTIDANSGDILEKSSEPVYD"
     gene            complement(12159..12359)
                     /locus_tag="TV188_000853"
     CDS             complement(12159..12359)
                     /locus_tag="TV188_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1534227.1"
                     /translation="MEHYRALAISEMQDISGGNAAGNAVIGGLGGLKTGITFCKIPHP
                     VLKGVCIDGFTALGACLAYKVN"
     gene            complement(12418..12573)
                     /locus_tag="TV188_000854"
     CDS             complement(12418..12573)
                     /locus_tag="TV188_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1534228.1"
                     /translation="MATEMLASFEGGKNNWAANVSGVIGAGSAGAALGFPVCGVACGS
                     IGVTGGF"
     gene            complement(13079..13945)
                     /gene="rsmI"
                     /locus_tag="TV188_000855"
     CDS             complement(13079..13945)
                     /gene="rsmI"
                     /locus_tag="TV188_000855"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEL1534229.1"
                     /translation="MQIQKSFKEEKESGVLYLVPTPIGNLEDMTFRAVNVLKEVDIIC
                     AEDTRNTGLLLKHFGIKTKQVSFHEHNAYDKIPDLLDLLLAGRSLAQVSDAGMPSISD
                     PGHELVRAAIDRDITVVALPGASAGITGLIASGLAPQPHLFYGFLPRKAGQQRAFLMT
                     KADYPETQIFYESPYRVKDTLTNLLACYGDRQVVLVRELTKLFEEYQRGQISEVLTYL
                     ADHPLKGECLLIVAGANQADASEPAEDLDLLALVQQAIAAGMKPNQAIKTIAKDYKVN
                     RQELYQQFHGLG"
     gene            complement(13950..14273)
                     /gene="yabA"
                     /locus_tag="TV188_000856"
     CDS             complement(13950..14273)
                     /gene="yabA"
                     /locus_tag="TV188_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEL1534230.1"
                     /translation="MNKKELFDAFDGFSQNLMVTLAEIEAMKKQVQGLVEENTILRLE
                     NTKLRERLSQLEHENLAKTSSKQGKDHLEGIYDEGFHICNFFYGQRRENDEECMFCRE
                     LLDRK"
     gene            complement(14266..15066)
                     /locus_tag="TV188_000857"
     CDS             complement(14266..15066)
                     /locus_tag="TV188_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1534231.1"
                     /translation="MISTIGIKYCDTCSVRYVQTDQAFPVQTKLVISDGKGSRLAVVN
                     SPIKSFCKDDLPKDMPSVLRPANDMDYKAYQQNLQLAAQSKQKVAEMIDRNGLDMTLV
                     DIVFSLERRYVLITFTAQERVDFRQLLKDLAAYFKTRIELRQINSREEARVYGGLGPC
                     GRPLCCSSFLGEFPPVSIKMLKHQGLSLHSAKSLGCCGRLLCCLQYEDDFYQESKKKF
                     PDYGTIVRTAQGPGEVAGIDLFTDTIQVRFKDQLALVTYALEEVKVSE"
     gene            complement(15063..15938)
                     /locus_tag="TV188_000858"
     CDS             complement(15063..15938)
                     /locus_tag="TV188_000858"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEL1534232.1"
                     /translation="MDLAQKAPRVYQAFQEILQKKRLNHAYLFSGDFANFDMALFLAK
                     TLFCEQKRGNAPCHHCRACQLIEHNDFSDVTILEPVGQLIKTDTVKEMMTNFSQTGYE
                     GRRQVFIIKDCDKMHVNAANSILKYIEEPQGDCYMFLLTNDDNQVLPTIKSRTQVFHF
                     PKDEHYLSELAQKKGLLKHQADLLARLAANAQQLTAFSENTRLLELMAQAERFVSIWF
                     QDKEQAYLELNRLVQLAEEKEEQDMALTLLTLILAKDYSRQNAFTYLEAVYQARLMWQ
                     SNVSFQNTLEYMVIS"
     gene            complement(15952..16587)
                     /locus_tag="TV188_000859"
     CDS             complement(15952..16587)
                     /locus_tag="TV188_000859"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEL1534233.1"
                     /translation="MTRGKLITFEGPDGAGKTTVLERLVPLLQAALGQTIVTTREPGG
                     VAIAEKIRQLILDVSHTTMDDKTELLLYIAARRQHLVEKIMPALESGHLVLVDRFIDS
                     SVAYQGAGRGLDKQAIQWLNHFATDGVDPDLTLYFDVPSELGLARIAQNTEREINRLD
                     LEQLDLHQRVRKGYLELALENPQRIVKIDASQDLESVVSAALAAIITHSQA"
     gene            complement(16903..17187)
                     /locus_tag="TV188_000860"
     CDS             complement(16903..17187)
                     /locus_tag="TV188_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEL1534234.1"
                     /translation="MFQKQQRIGLVIYLYYNRDARKVMKYGDLYYHSRRSRYLVIYIN
                     KEDMEEKLKDISRLTFVKEVKVSAFDDIDCDFVGNLHREPLEPQALPEQG"
     gene            complement(17188..17634)
                     /locus_tag="TV188_000861"
     CDS             complement(17188..17634)
                     /locus_tag="TV188_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HEL1534235.1"
                     /translation="MLIINEELFAIEKAIEQLVQDIRTSSQYQAYALAKKAFEADLAL
                     QTELALFEELKQDYELRQDLLKLCPDARALRCQLLHQKRQLDLHPLVADLRLAQVDLQ
                     EVLATISTAIAEAVSEDILVDTGLPLATNRPRHELGPYQNIKEKST"
     gene            complement(17739..18329)
                     /locus_tag="TV188_000862"
     CDS             complement(17739..18329)
                     /locus_tag="TV188_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HEL1534236.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
                     TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELA"
     gene            complement(18560..19189)
                     /gene="upp"
                     /locus_tag="TV188_000863"
     CDS             complement(18560..19189)
                     /gene="upp"
                     /locus_tag="TV188_000863"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEL1534237.1"
                     /translation="MGKCQVISHPLIQHKLSILRRQDTSTKDFRELVNEIAMLMGYEV
                     SRDLPLEDVEIQTPVAKTVQKQLAGKKLAIVPILRAGIGMVDGFLSLVPAAKVGHIGM
                     YRNEETLEPVEYLVKLPEDIDQRQIFIVDPMLATGGSAILAVDSLKKRGAANIKFVCL
                     VAAPEGVKKLQEAHPDVDIYTAALDERLNDHGYIVPGLGDAGDRLFGTK"
     gene            complement(19339..20970)
                     /locus_tag="TV188_000864"
     CDS             complement(19339..20970)
                     /locus_tag="TV188_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEL1534238.1"
                     /translation="MSTEKKQLTQEQLMVQGAAWSTAGNFISRLLGVLYIIPWYIWMG
                     QYAIQANALFNMGYNVYAYFLLISTTGLNVAIAKQVAKYNSMGQQEHSYQLIRSTLKV
                     MLVLGLIFSVLMYLGSPLFARLSGGDETLVPIMHSLSLAVFVFPVMSVIRGIFQGYKE
                     IKPYALSQIAEQLVRVIWMLLTTFFIMKMGSKDYIAAVTQSTFAAFIGMIASMAVLFY
                     YFWTQGLLKAIFTKTEHAIPIDIKGLLIETLKESIPFIITGSAIQAFQLLDQWTFVNT
                     MTLFTSYTRSQLWVLFGYFNANPAKITMVLIAVAASIGSVGIALLTENYIKKDMRAAG
                     RLIINNIEMLLMFLLPALTGAIILARPLYTVFYGSSEGQAVRLFVAVLCLTLLMALYT
                     LFSPMLQALFENRKAIYYFAYGVFVKLVLQVPLIYLFHAYGPLLATTLGLLVPIYLMY
                     RRLHQVTRFNRKLLHKRILLTVIETALMGLIVLLANWFLGYLFKPTGRLTSLLYLVII
                     GGLGMGVYAYMTLLTRQLDKLIGSRAARYRQKLGL"
     gene            21056..22501
                     /locus_tag="TV188_000865"
     CDS             21056..22501
                     /locus_tag="TV188_000865"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEL1534239.1"
                     /translation="MITIEHLLTILKKDHNFREVLDQDGYHFNYSGLQFDSLSYDSRQ
                     ADEQTLFFAKGSAFKADFLRQAIAKGLRLYVSEIDYQVGIPVILVNNIKHAMSLAAMA
                     FYDYPQNKLKLLAFTGTKGKTTAAYFAYHMLKESHKPALLSTMNTTLDGQHFFKSQLT
                     TPESLDLFAMMAQCVANGMTHLVMEVSSQAYLVGRIYGLTFDVGVFLNISPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVVVNSGMEHFNILAEQVADKPHDFYGKGACNRLLQRQA
                     FSFQAAGKVAGDYAIQLIGSFNQENAMAAGLACLRLGASLEDIRQGIAKTNVPGRMEV
                     LTMTNQAKVFVDYAHNGDSLEKLLSVVEEYQKGQIYLILGAPGNKGESRRADFGQVIN
                     QHPNVRIILTADDPNFEDPQLISEEIASYIHREVDIIIDRKEAIKTGMERCQNEQDAL
                     IIAGKGADAYQIVKGQKTAYAGDLAIAKSYL"
     gene            22761..23540
                     /locus_tag="TV188_000866"
     CDS             22761..23540
                     /locus_tag="TV188_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534240.1"
                     /translation="MSTISAERISAGYDQSLIISNLSVTIPEGKVTTIIGANGCGKST
                     LLKTLARLLPLKAGQVLLDGQAIARLATKDVARTLAVLPQLQEATTATVYELVSYGRY
                     PHQSYLGQLSQADKDKICWAMEVTSMAPYAHQAVDALSGGQRQRAWIAMALAQDTDII
                     FLDEPTTYLDMNHQLDILELLKELNQVSGKTIVMVLHDLNLSARYSDHLIAMKNGHIK
                     YSGEVNQVMTPEMIQDIFQVKAQLVTDPLYHCPTLLTYQLI"
     gene            23565..24503
                     /locus_tag="TV188_000867"
     CDS             23565..24503
                     /locus_tag="TV188_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HEL1534241.1"
                     /translation="MKKLLLILTVFVTAFTLVACSSQSKQQESTSKASLSHKPKIAGV
                     TYYGDIPVKPKRVVSLAATYTGYLAKLDLHLVGVTSYDKKNPVLTKSITQAKQVAATD
                     LEAITALEPDLIVVGSTEENIDQLAKIAPLISIEYRKRDYLQVFSDFGRIFNKEKETD
                     QWLADWKQKTSDYEKEIKQVTGSAATFTIMGLYEKEIYLFGKDWGRGGEIIHQALHYD
                     APEKVKKEVFKQGYLSLSQEVLPDYIGDYVIVAAEDDQTGSALYESDLWQQIPAVTNN
                     HVIKVNANVFYFTDPLSLEHQLEVLKKAILSTGASQ"
     gene            24513..25538
                     /locus_tag="TV188_000868"
     CDS             24513..25538
                     /locus_tag="TV188_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1534242.1"
                     /translation="MTAQHHTKPKLAKAAPPWLILTFISLTLVLAIYCSLRFGAVSLS
                     HQELYHILLGKQDQGQKASIILDIRLPRLILAALVGAALAVSGAIMQGITRNPIAEPG
                     LLGINSGAGLALVIGYAFSPHLHYSTIILLSLLGSLLATLLILSLAYQAGKGYTQMRL
                     ILAGAMISMLLSAIGQGITTYCHLANAIIGWQAGGLIGVNWQMVSYVAPLIICGLALS
                     YLLAYHLTILSLSQEQAKALGQRTFLISLIFIGLVLLLSSAAVAVAGSISFVGLIIPH
                     AITLVTAKDYRWILPLATLLGASFMLWVDFACRNINPPYETPLSALISFIGLPCFLWL
                     VRKGGRF"
     gene            25535..26533
                     /locus_tag="TV188_000869"
     CDS             25535..26533
                     /locus_tag="TV188_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1534243.1"
                     /translation="MTATKRHVPLFLGLISGLVCLMIISLSIGESSMSPLEVVRVLFG
                     KSTADMALIITNIRLPRILAACIGGGSLALSGLMLQSLTRNHLADSGILGINAGAGMA
                     ITLVISYSTSNSLTSRQGLPLMTISGAMATIVLVYLLSLRHGHIDPIRLIVTGVGLST
                     MLSSLMIAFVGNVNRYKVDYVIHWLSGQLTGDDWSKLSIVAPLLGITWLLAFSQAYKL
                     NIMALNDEASMALGFKLHQYRTIVLALSAILSALSVILVGNITFIGLIAGHTSKRLVG
                     ADHRLSLPVSLFIGMILLLLADTIGRVYLVGSNIPTGILVSIIGASYFLYLMVKMT"
     gene            complement(26638..27291)
                     /locus_tag="TV188_000870"
     CDS             complement(26638..27291)
                     /locus_tag="TV188_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEL1534244.1"
                     /translation="MITIFNPDKLTRQPFFQDLIHYLNQHDDVTLRHIKQAFSHVKGI
                     DKALEAYIQAGYICRKNRRYYLCLPLLDDLQQVTLEDLIFVDRASDLYEALMALVFET
                     VLSNQTNQVLIKEKTTIDRDKLTLANYFYRLRRGEALSDEQLRLYALLGDVNQDYALK
                     YMTSFLLKFARKEIVMQKRTDIFVNALELLGYIEKVEATKYCLKLAFDKEQLIFYAD"
     gene            complement(27358..28293)
                     /locus_tag="TV188_000871"
     CDS             complement(27358..28293)
                     /locus_tag="TV188_000871"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEL1534245.1"
                     /translation="MSKLLVFGHQNPDTDAIASSYAFDYLAKKAFDLDTEVVALGDPN
                     EETAFALDYFGVSAPRVVTSAKAEGASHVILTDHNEFPQSISDIREVEVYGIVDHHRV
                     ANFETANPLYMRVEPVGSASSIVYRLFKENRVDVPKDIAGMLLSGLISDTLLLKSPTT
                     HASDHRVAAELAELAGVKLEEYGMAMLKAGTNLASKSEAELIDIDAKTFELNGNAVRV
                     AQVNTVDIAEVLERKEAIEAAIREVMASEGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFSFKLEDNHAFLAGAVSRKKQVVPQLTESFGA"
     gene            complement(28793..29584)
                     /gene="pflA"
                     /locus_tag="TV188_000872"
     CDS             complement(28793..29584)
                     /gene="pflA"
                     /locus_tag="TV188_000872"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEL1534246.1"
                     /translation="MVEVDYGQVTGMVHSTESFGSVDGPGIRFIIFLQGCKMRCQYCH
                     NPDTWAMETNQSQRRTVNDVLKEALQYRHFWGKKGGITVSGGEAMLQMDFITALFTEA
                     KKLGIHTTLDTCGFAYRPTPEYHELLETLLAVTDLILLDLKEIDEEQHKLVTRQPNKN
                     ILQFARYLSDRQVPVWIRHVLVPGLTDIDDHLVRLDAFVKTLRNVDKFEVLPYHTMGE
                     FKWRELGIPYQLEGVKPPTKERVENAKKLLHTESYTEYMNRIHQS"
     gene            complement(29661..30995)
                     /locus_tag="TV188_000873"
     CDS             complement(29661..30995)
                     /locus_tag="TV188_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEL1534247.1"
                     /translation="MEDPVSQPLLIQFLLLVILTLLNAFFSASEMALVSLNRSRVEQK
                     AADGDKRYDRLLRVLEQPNNFLSTIQVGITFISLLSGASLSASLGQVISGWLGGSATA
                     QTAGSIISLVFLTYVSIVLGELYPKRIAMNLKDKLAVISAPVIIILGKLVSPFVWLLS
                     ASTNLLSRITPMTFDDADERMTRDEIEYMLTNSEATLDAEEIEMLQGIFSLDEMMARE
                     VMVPRTDAFMIDINDDTLDNIKEILKQSFSRIPVYDVDKDKVIGLIHTKRLLESGFRQ
                     GFENISMRKLLQEPLFVPETIFVDDLLRQLRNTQNQMAILLDEYGGVAGLVTLEDLLE
                     EIVGEIDDETDKAEQFVHHIDDNTYIVTGTMTLNDFNEYFDTELESDDVDTIAGFYLT
                     GIGTIPSQKEKESFACDSKQKHLVLVNDKVKDGRITKLKLTISNIEQNITED"
     gene            complement(31123..31680)
                     /locus_tag="TV188_000874"
     CDS             complement(31123..31680)
                     /locus_tag="TV188_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1534248.1"
                     /translation="MIKRPIHVSHEFLKEVLDKQSIAVDATMGNGYDTAFLASLSQRV
                     YAFDVQQQALTKTQERLEQQGLTNAELILAGHEQVDQYVKEPIRAAIFNLGYLPNADK
                     SLITRPETTILALAKILDRLELGGRIAIMVYYGHDGGSREKEELLDYIGQLNQRQVTA
                     MLYQPINQMNQPPFLIMLEKIAATD"
     gene            complement(31690..32475)
                     /locus_tag="TV188_000875"
     CDS             complement(31690..32475)
                     /locus_tag="TV188_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEL1534249.1"
                     /translation="MKQRLIAGEELSLPPVLKKLLQNSLVYDSSSSAEARVYAIDKGQ
                     GYFLKTAAKGRLAKEAALTRYCHSKGLATEVLDYISGDQDWLLTAKVAGEDASHIEYL
                     SDPKRLCRILVDHMLKLHSLSLSDFPVADKTLAYIEAAEAGYHQGRFNQCFLPPQQRF
                     QSQEEAYRRIQELKLLLQHETLIHGDFCLPNMILDRWQFQSMIDWGEAGKSDRHIDLF
                     WLIWSLQFNLKTDRYKDYVLDCYGRRHIDLDILDGIAAFEVFA"
     gene            complement(32488..33411)
                     /locus_tag="TV188_000876"
     CDS             complement(32488..33411)
                     /locus_tag="TV188_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623410.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HEL1534250.1"
                     /translation="MTKRYQTLNEYYRRLFGAKIFKVPIDAGFDCPNRDGTVAHGGCT
                     FCTVSGSGDAIVAPDAPIREQFYKEIDFMHRKWPEVNQYLVYFQNFTNTHDKLEVIRE
                     RYEQAINEPGVVGINIGTRPDCLPDETIAYLAELSERMHVTVELGLQTTYEATSQLIN
                     RAHSYDLYKETVQRLRQYPNINIVSHLINGLPGETHEMMIENVRRCVTDNDIQGIKLH
                     LLHLMTNTRMQRDYHEGRLQLLSQKDYVSIICDQLEIIPEHIIIHRITGDAPRDMLIG
                     PMWSLNKWEVLNAIDLEMERRNSWQGCKLKG"
     gene            complement(33602..34252)
                     /locus_tag="TV188_000877"
     CDS             complement(33602..34252)
                     /locus_tag="TV188_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEL1534251.1"
                     /translation="MKHKQQHLLLSSFAMLLFVVLGYIVKFFPEDLTSFDSQLRLALR
                     GHLPEGLTQFFKGITVAGNVSTQAVIVVVAVLALLALSWRAEALFVLSNGVFAALLIW
                     VLKLLYQRPRPSIEHLVHASGYSFPSGHSMGSLLIIGSLLIICHQRLQSASLRWLVDI
                     ALLALILLIGLSRIYLGVHYPSDVLAGYALGFGILQLLYPFYDQKRFEWRFQLKQK"
     gene            complement(34242..34820)
                     /locus_tag="TV188_000878"
     CDS             complement(34242..34820)
                     /locus_tag="TV188_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007894892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1534252.1"
                     /translation="MSKTHQLVMVAILSAISFCLMFVGFSIIPGASFLKIDFSIIPIL
                     LGLVLMDLKQANLILAVRTLLRLALNNHGVNDLIGIPMNVIAVALFITAFALIWHRQK
                     GLVTYVLASLVGTGLLTLGMVVMNYVFAIPLYAKFAGFDIKAFIGTARYIFTMVIPFN
                     LLEGLIFAIVFYFVYIAGKPILERYPNSYHET"
     regulatory      complement(34893..35018)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
BASE COUNT        10494 a         8496 c         7080 g         9643 t
ORIGIN      
        1 accgacgata gttttattgc tgtttttgat cctaagctca aagaaattga taagcatatc
       61 tttgaggatt ctgtcattgc tagcgatttt tcagttgatg gagatgacat ttacctctta
      121 ggaacagatg tgaaaatcaa ggataactac ccaacctact tatatacgct atctatcaaa
      181 aatgggcaat tagctatgaa aaacaaagag ctgctctatg aacagcctga atccacttac
      241 tttttccatg atagcattgt caaagaaaag cagctctata ccgccttaag cggctatcga
      301 aacaatgtta ccaaggagag aaccgtttta gggcaggttt tccattatga tatgcagtca
      361 ggtcaaaaac attttttcga tctcactgag attgctccag tcaacatttt tgatttgggt
      421 cacgatacac tggcaataga gcatgagaaa aatgaagctg gaaaaattgg gtttagcctg
      481 tttcacctca atgataaaac gtctactttt attgacttat ctcaatttgg tttatccatt
      541 gaaagtgact acttaaaaga tgtcaaacaa attgacgaga acaccctatt aatattagct
      601 ggtcatacat taatcggata ccatatcaat gaccatcaag ctatctttaa caaacaagtg
      661 agtgatgatg cctttcatat atgggtaaaa tagctactca gttactgaaa acaacaaaag
      721 gtcaaagcac aagtccttga ctttttagtt aaaatagtta ggctagcttt ttctaagaag
      781 ctagcctaaa ttagtagtat ttggaactgc cattaagatg tgataaagcc agcatgcttg
      841 tgatgggtta tcagaatgtc acttcaatcc aaacgtcata aaagctcttt ttgaaaatgg
      901 tttagcacat gactgttgat ctaaagctag cagctgcaac agttgagtta gcttttttcg
      961 tgaggctccc aaagctatgt gtcgagcaac atcactaaca gctttaggag cttgatcttg
     1021 atgccccaca agctagcacc gtagggcact gctagcttgc taaagctttt tgctttcttt
     1081 tttcaatagc tgctctagct tttaacatat agttactgca attactctca ctatttgagc
     1141 tagaaccaaa acttcgtcac atcttacctt ggccaatctg gagaattaat accccagagc
     1201 tatttacatc ttattcagat ttttccaaaa gcttctttga atccagagct gggcaaagag
     1261 caaacagcta agaagaataa ggctcacagc aatgctcaca agaagaggct gctgactaat
     1321 ggtagcacac ataatcgcta aaacaatcaa aaagccacca acaattaagt cgccaaacat
     1381 cagcccaagc ataaaccatt ggctatttcc tctggtgaaa agctgggtga cgtcctgcca
     1441 tttcagatcc agcatgcggt aatcacgcct aaacatcaat tgcccttgta tgattcccat
     1501 caagacaaag cctaatgaaa aggataggac aataacgggg tgaaagccta atacaaacaa
     1561 tccaataaga gcataaacca ccaagggagc aaggatttgc agccctatca gcaagcgaaa
     1621 tttgttaagc aaaaagccct ttaagctaat gggtagggtc ttaataaagg tgaaattgtc
     1681 cttttcaaga gagatcccaa caccaacaaa gctggtcggc acagtacata tacttcccaa
     1741 gagcaccccc accaaaagcg caataccaaa gtactcatcg gtaatgtagc ttgaaaattg
     1801 tgcaccactt gtcacactag gagtgataaa gatcatcaca taaatcaaag gcatcagata
     1861 agtctgtgtc aatagtgtcg cattttgcag cgttgcaaga tggtgctttg tcaacaatcg
     1921 ctgtagactt tgctgacgat cagatgcagc cgccttgcgc gccactgctg catttttagc
     1981 ttttccacca acatagaggg tctctctgta ataagccggc atgatccgtc taacaagacc
     2041 atacagcatc agcatgacca aaagcaaggg aagccaaaaa ttaagcagag cctgactgga
     2101 aaacggtgcc acaacaacat catagctgcc cctaaaataa ggaatcaaag ggcgatctga
     2161 aaaggcttga tcagccatca ttcgctgatt gttagtcata ttgagaaata caatcaagcc
     2221 tagagcacca aaggtagaag caaacatcaa aaccgctgaa atcagcctgc gcttactact
     2281 cctcagaata atcctgccaa tccaagcatt gagatacaga gcaaaaacaa tcgagctgac
     2341 aaatagcacc acaaacagga taaacgctag cacaatcgcc aaagcatttc caatgatctg
     2401 ccagtaggca atcacgaaaa ggcttagcag cggcattaaa aatatggatc ccatacctaa
     2461 tgaggaaatc agcttagcaa tgaaaagctc ctcagatctt atcggcagat gaacatagag
     2521 cttaacgtca ttactctcat aaaagaccgc atacattgcc gtaaaggcat taacagttgc
     2581 cataacaaag aaaatagcaa tataaagtga caacagtccc ggatattggc taaaatcaac
     2641 acccataaac ataaagatgt aaatgactaa aaacagagca atcatcaagg cttgctgtct
     2701 gatcatactc ttgtaggcct tgaagttctc tttgggagcc ttttcttgct ttttctttaa
     2761 agctgtcagg gactgaggat tggaataaag gatattaatc ttgactaatt cccaaatagt
     2821 tgaccaattc ataccactat gcctcctgtg cttgacgtcc tgccaattca aggtaaatag
     2881 tctccagatc cttatcagga taatcagcct ttagctgctc aactgtccca acaaaaatca
     2941 atttcccctt tttcaaaatc ccaatccggt cacacagctg ctcagcaacc gacaagacat
     3001 gcgttgaaaa aagaaccgta ttaccagaag cagcatgctc tttcatcatt tcctttagat
     3061 caaatgaagc ctgaggatcc agtccagtca agggctcatc aaggatccag atactagggt
     3121 tggagatcaa agcaccaatc acaatgacct tttgacgcat accatgtgaa aagttatcaa
     3181 tcgtgttgtg catctcctgc gtcagctcaa ataactgcgt cagctcctca atccgagctt
     3241 tggtatccgc ctcactgacg ccataaatct tagcaagaaa ctgccaatat tcataggctg
     3301 tcaggtttaa gaaaatatcc ggtgaatcag gcacatagcc gatttgcctt ttaatggtgt
     3361 tacgatgctc actcagcagc tgaccattga ccaagacctc tctatagctt gcttcgataa
     3421 tagaggtcag gatactgatt gttgtcgtct tgccagcccc attgtgacca atgagaccaa
     3481 agatttcacc gtccttaatc gtgaggctta catcactcaa ggcctccttg tcaccgtata
     3541 gctttgaaac atgtctaaat tctatcataa ctctctccta tcctaaacca gacgctcgtg
     3601 ctggtcagcc tttttctaat aaataagcgt caagcgactg cttaaagcca cacaaggact
     3661 taggcaacaa caaatcattg gcctgtaagt aatcatcaag cgcttgattt agctgctctg
     3721 caatcgtcag cggattactg tttttgatta attggttaga agctgacagc aataatctgg
     3781 ctaaatggct attagcacga ttttctgggt aatcgtaggc ctgtttgatg acatcgtata
     3841 agcgctgctg ttccttttcc atagggcctc cctctaattt tgtacgttta cgctaataca
     3901 actagttaac acttcaatca taatctttat taggcttttt gtcaatatcc tatcgccata
     3961 tttgtctctt ttcacaaaag cagatatacc aacgatgatg gcgcttactt ttgttccttt
     4021 tttagggcaa tacgggcagt cagttgtgct tcttattttt agccataggt aacaaaatca
     4081 gacgataatc gttttcatta aaaaaaaaaa aaacgaaact acggagacaa actaatcagc
     4141 agctatttct tacatttagc tagcgtgtta agatagctat tggaaaagat ttttaggaat
     4201 acttcatatt tctatcatca aaggagagag aaatgataaa taaaagaaag aaaaaactta
     4261 tctacaggta tggtgtctgc tcggcagcag ttatcctagc agcgcttgct agcctaggaa
     4321 catgtaaaga agcaaaagca ttatctggtc cgccaggata cccacttact cgtgatttct
     4381 cccgtaactt cctagaagaa aatactgcaa aatatttaga tcaattaaga gaacatctac
     4441 agcacagatt tagtgaactt gagagcttaa caagaaaatt agagaaagaa ggcggtaccc
     4501 gaggtccagc agggcctccg gggccagccg gacctaaagg ggaacgtggc gaaccagggc
     4561 ctgttggacc tatgggacct agaggtgaac aaggtcctaa aggcttagac ggagcacgtg
     4621 ggcccgaggg acagcaagga aaacctggac ctgtcggacc tcaagggccg gcaggtccag
     4681 cggggcaaaa aggggaaacc ggacctcagg gacctcgtgg agataagggc gatactggag
     4741 aaactggaaa gcaaggacca gcaggagaac gtgggccagc tggacctcag ggaccgcgcg
     4801 gagacaaggg tgaaaacggt gcacccggtg agcaaggccc tattggtcca aaaggtgaga
     4861 ctggacctaa aggtgacaag ggagaacgcg gcgaaaaggg cgaccaaggt caacgtggtg
     4921 aaaagggcga ccaaggtcaa cgtggtgaaa agggcgacca aggtcaacgc ggtgaaaaag
     4981 gcgagcaagg ccaacgtggt gaaaagggcg agcaaggcca acgtggtgaa aagggcgagc
     5041 aagggccacg cggtgaaaaa ggcgagcaag ggccacgcgg tgaaaaaggc gaccaaggtc
     5101 aacgtggtga aaagggcgac caaggtcaac gcggtgaaaa aggcgagcaa ggccaacgtg
     5161 gtgaaaaggg cgagcaaggg ccacgcggtg aaaaaggcga gcaagggcca cgcggtgaaa
     5221 aaggcgagca aggtcaacgc ggcgaaaaag gcgaccaagg tcagcgcggt gaaaaaggcg
     5281 accaaggtca acgtggcgaa aaaggcgacc aaggtcaacg cggtgaaaaa ggcgaccaag
     5341 gtcaacgtgg cgaaaaaggc gagcaaggtc aacgcggtga aaatggtgag caacagccaa
     5401 agggtgacca aggaaaggat accaagccat cagttccaaa ggcaccagaa tcaccaaaaa
     5461 tgccagagaa gccacaggct cctgaaaagg ctcctgcacc gaaagctcca aaggcttcag
     5521 agcagtcagc tagccctaag gcaccagcac ctcagtcaac accaagcaaa aaagcagtcc
     5581 taccagctac aggagaggca agccatccat tctttagtct ggcagctctt agcgtcatcg
     5641 ctagcgcagg tctgctaacc ctaaaaagaa agaaaagcta agccagctat ttgacaatag
     5701 cttctagcaa ctcgggatag atctgcaagg ctgagcagta gcactattaa atctgaaaca
     5761 aaaacgcatg acgtcctccc taaaaagggt tgaacatcat gcgttttttt gtctaataat
     5821 gccgaaagca agcctagata aggcctgctc cagcttaatc acttatgata aggatttgta
     5881 caattcagta gcatgctcta ctgtaaagcc atattcttca aagatacgat tgcccggtgc
     5941 agaagctccc catgtatcaa tggtcagtgt tttccctgca aggccaacgt attttgccca
     6001 gccaaagctt gagcctgctt caatagctag acgttttgtc actgctgctg gtaggatttc
     6061 ctccttgtag gaagctggct gctcatcaaa gatattttgt gatggcattg ataccacacg
     6121 cacatggata ccatctgctg caagagcggc ttgagtatcc attgctagct tgacttcaga
     6181 gccggttgca atgataatcc catcaaggtc accctttgcc tctgacagga tataagctcc
     6241 cttattaagg ccatcttctg ccaattcctt agtaccttca agtacaggaa ggttttgacg
     6301 tgttaagaca agcattgtcg gacggtctgt ctcagcgatc gcacgcttcc aagcagcgtt
     6361 tgtttcattg ccgtcagctg gacgaataac gttcagattt ggcattgatc gaacactagc
     6421 tagctgctcg attggctcat gggtcggacc atcttcacca accgcgatag aatcatgcgt
     6481 catgacataa accgttggta gctgctgcaa ggctgccata cgaaccgctg gcaataggta
     6541 gtttgaaaag acaaagaagg ttccgccata aacacgtgtt ccaccatgaa gggcaatacc
     6601 gttcatcgct gctgccattg caaattcgcg tacgccaaac cagatgttac gaccagcata
     6661 atgacccggc tggaagtctg tctcagcctt aaccatggta ttgttagagg cagaaaggtc
     6721 agctgagcct ccccagaagg ctggcacctg ctcagagatt tgttggatag cctgctggct
     6781 agaaacacga ctggctactg ctgtgccaag ctcgtgagct tgcaactcaa cctctgccgc
     6841 ctcattagca aaggcttttt tgtattcggc tgctaactca gggtatgctg cttcataagc
     6901 tgcaaatagg tcattccatg cctgctcagc ctgctcacca cgcgcctgaa ggccttgtct
     6961 aaagcgctca gtcacctctt gcggcacctc aaaatcagca tgggtccatt gataagattt
     7021 cttagcaaag gcaatgcctt ctgcaccaag cggagcccca tgaacagctg aagttccttg
     7081 cttttcagca ccaaagccaa tgattgtctt tacttcaata atggttggct tttcagtctc
     7141 tgccttagct tcctcgatag ctttagcaat ggcctctagg tcgttgccgt ctttaacaag
     7201 gatatgctgc cagccgtaag cttcaaaacg ccccttgacg tcttctgtga aggccattga
     7261 ggttgggcca tcaagcgaaa tatcgtttga atcatatagc aagacaagct taccaagctt
     7321 caagtgacct gccagactgg ctgcctcctg actgacaccc tccataaggt ctccgtcacc
     7381 atttagagca taggtatagt ggtctacaat atcaaagcca ggtctattga acttagctgc
     7441 taagtgtgcc tctgccatag ccataccaac tgcattggca actccttgtc ctaaaggccc
     7501 tgtggttgcc tcaacgccat ctgtatgatt gacctctggg tgacctggtg ttttagagcc
     7561 ccattgacgg aagttcttaa gatcctcaat agacacatca tagcctgcta ggtgcaacag
     7621 gctgtaaagc atggcactac catgacctgc tgataggata aagcggtctc tatttgacca
     7681 acggcggctt gtctttggat tgactgtcat aacatgattc catagcacat aagccatcgg
     7741 cgccgccccc atcggcaaac ctggatgccc agaatttgct gcttgaatag cgtccattga
     7801 tagagtacga acagtattaa ctgccagctg atcaattgca tcaaatgtca taagtaaaac
     7861 ctctctgtgt attacaacta aaaattaaac gttttccatt gtctattgta acataaaagt
     7921 aaactgattt ttaacaaaat cctataaagt ccttaaattc ttatctagca ataagcattg
     7981 ctgttcctag ctttttgtga ttgacagctg tcttagatag agcacctatg ctcataagaa
     8041 aaagcaagcc tagctgttgc cagctaagca agcattcctc tttggtacct ccctttggct
     8101 acagtaagcg ccagctgcct gttaattcta gcgcaacagc aaagcaccag ctgatcctgc
     8161 cacctacaaa tagctaatcc caaactaacc gctacagcca cattagaata taaggagagc
     8221 tctatgctct tagcctattt tttaaaggaa gcccaatcct ccataaaggt ctttaagcca
     8281 tttgttgtca atgggtgctc agtcatcttc gcaaataatg gatctggaat ggttgcaatg
     8341 tgtgccccta gctgtgcaac agcttcaaca tgggcagctg tccgaatgct ggctgcgatg
     8401 atttctgctt ggaagccata caaatcaatg atcccacgca aatcactaat aagctgataa
     8461 ggatctgctc caatatcctc taagcgacca ataaatggac tgatataggt cgcaccagcc
     8521 ttcatggcca ttagtccctg actaactgta aaaataagcg tcacatttgt tttgatgcct
     8581 tcttgtgaca agacattagt tgcttttaag ccctctgtcg tcatcggaat tttcacgacc
     8641 acattgtcat gccacttggc aatgttccta gcctctgcaa tcatttcctc tgcggttagt
     8701 ccggtgacct ctgcactgat agggccgtcc acaatctcac agatttcctt gataactgtc
     8761 tcaaaatcac gaccctcacg cgagataatg ctagggtttg tggtaacacc gtccacaaca
     8821 ccaagctcat taatcgcacg aattgcctct acatttgctg tgtctaagaa aaatttcatc
     8881 ttaacctccg ttaattagtc tgttatcagt cattgaacag catgacgctg tttaccgtct
     8941 acattatcat tataaaagtc actcttagga tataaaagac caagtatcac acagtctagt
     9001 gttcaaaact agacctagct atgggactct gtttctttaa aaggcttgat tcttacagct
     9061 cctctgcaaa aaactgtgtg gctttgacag ctcttttcca gccttgatat aacttttctc
     9121 ggcgagactc actcatgctt gctttaaaca gctgacctgt agcatttaat tgctttagtg
     9181 tctccatgtc cttccagtag cctacagcaa gcccggctaa aaaggctgct cctagagctg
     9241 tggtttcaag attttcagca cgagcaatat caatccctaa aatatctgcc tgaaactgca
     9301 tgagcatgtt attcatagcc gctccgccat caacacgtaa ttgctggata gtgatccctg
     9361 agtccacctg catggtatca atcacatctc tgacctgata agcaatagac tgtagggtag
     9421 ccttaacaaa atcctctttt gttgttccac gcgttaagcc aaatactgag ccgcgtgcat
     9481 tggaatccca ataaggagcg ccaagacctg taaaggctgg tacaacatat acctcatcag
     9541 cattggttga agccaaggct agctgttcag actcaaaaga ggtttttatc attcgcaagc
     9601 catctcgtag ccattgcaca gcagagccag caataaagat agacccttct aaggcataat
     9661 aaaccttgcc attaatacca tatccaatcg ttgttagcag gttgctgctg gataattgag
     9721 cctcttgacc agtattcatg atgataaaag agcctgtgcc ataggtattt tttaccatac
     9781 caggctcaaa ggccagttgc ccaaataggg ctgcctgctg atcacctgcc atgccagcaa
     9841 tagctacctc tcctccgtaa aaatgaaaag aagccgtttt accataaatt tccgaattag
     9901 acctgacctc aggaagcatg gccttaggga tattcagcaa ggccaatatc tcatcgtccc
     9961 attttagctc tttgatattg tatagcatgg tacgtgctgc attagaataa tccgtcacat
    10021 gtaccgcccc gtccgttagc ttccaaacca gccaggtgtc aatcgtgcca aataataatt
    10081 ctcccctttc agctcgctct tgagcccccg gaacatgatc aagaagccat ctgagcttgg
    10141 tcgcagaaaa ataagcatct ataaccaagc ctgttttttc atggatcatt ttggtatagc
    10201 catcacgctt tagctgctct gcaatggagg ctgtttgtct agattgccac acaatagcat
    10261 tatagatggg cagacctgtc tgtttgtccc agactaccgt tgtttcacgc tggttggtaa
    10321 tgcctatagc ttctatttgc tctggcttta taccagactc gataaaggcg tctgcaataa
    10381 cagactgcac caaattccaa atgtgattgg cgttgtgctc aacccagcca gcctgtggaa
    10441 aaagctgtgg aaattccttt tgactactaa ccagcgcttc tcctttctta ttgaaaataa
    10501 tggcacgaga gctcgttgtg ccctgatcaa tagccataat ataggtttca gttcccatgt
    10561 gtcctccatt ctatcgctgc tgagataggc tctctcaatc atagcaagcg ctttctactc
    10621 tattatacaa catttacagc ccatagccta tccttctagt cataaaagta tcactctgcc
    10681 aaatcctaag ctgataatgc ctatcatttc aactaaacag cccttatcac agccaaatac
    10741 cagcaacaaa ggcgggctat aggctagcgc ctaaatggct gccaacaagc tccagctcta
    10801 tcaggcacaa caaggaacaa caaaaaacct aagccctttt agcatataaa ggcttaggaa
    10861 tgttacaggc ttttatcaca taagcggtga tagcttttta atcgtaaaca ggctcagagg
    10921 acttttctaa aatatctcca ctattagcat caatagtata gctgtactcc tgatccttgg
    10981 cgtcaaactc aatatcgtag accaccctac cgtcgtctgt ttctttcgtc agctttagcc
    11041 tttgggcgtc agctgctgtg attgaggcgt ccttaaaagc aagctccttg gccttgtcct
    11101 ctgaaatgcc agctgcttga tcagcctgac caccagctgc ttgagctgaa gcaggagcct
    11161 cagtgattgg ctcagaggat ttttctagga tctcaccggt attagcgtca atggtatagc
    11221 tatactcctg atccttagca tcaaactcaa tatcatagac cactctacca tcgtctgttt
    11281 ctttcgtcag cttgagcctt tgagcgtcag ctgctgtgat tgaggcgtcc ttaaaggcaa
    11341 gttccttggc cttgtcctct gaaacacttg ccttcctatg attctgagca ctgccatttt
    11401 gacctagagc ctgattctgt tgacgacaag ctgataggct gattaaggat agactcgtaa
    11461 gagctattac tgaaagtttt ttgattatca ttgtattgac cttccgtctt tattcatctt
    11521 atttcctcta gtatacatta aataatctga ttttacaatt ttaaagcgct aaaactctct
    11581 taaccaggct tactccctta tatgataacc cccaaagagc ccataaggta aaggtaagga
    11641 ctttgctatc cctcaaccaa gaatagatca cccagccgaa taaaaaaagc aattattggt
    11701 agaatgagaa gaattatttt ggtcttattt attgccttca ccagctatca atcactattt
    11761 aatgaccatt ttggtatgaa ccctcactgc cactcactat ctgacaccaa gctactttta
    11821 agtaccagca tcgatgtttc ttacacctcc agtgcgtatc catagccgac cttcagcatt
    11881 taccagcatt tctgattgat tacaaatact ccctaaactg ttgaaaaagt atctaaacga
    11941 accatacaaa acttaattta ccttttttct atataaatag ctaaaaaaca tagtaaggtc
    12001 acaagggata taagatttac attgcttata gtagtcgata agaaataaaa aattaaaaaa
    12061 ataaagtaag aagccccttc tttgcccctc ttagcactgt caaccagtat atagataaaa
    12121 attaaagcat aaagacctga aaaagtaatc aataacatct aatttacctt atatgccaag
    12181 catgctccta aagcagtaaa gccgtctata catactcctt ttagcaccgg atgaggtatt
    12241 ttgcaaaatg taattcctgt cttgagacct cctaatcccc cgataacagc attacctgct
    12301 gcatttcctc ctgaaatatc ttgcatttca cttattgcta atgctctata atgttccatt
    12361 tctattatcc tcctaaaaca aggttccaaa ctcagaatct ttctgttttt ctcatttcta
    12421 aaagcctcct gtgacaccaa tagatccaca agctactcca catactggaa atccaagtgc
    12481 tgcgcctgca cttcctgctc caatcacacc tgacacattg gcagcccaat tattttttcc
    12541 tccttcaaag ctagcaagca tttctgtagc cattacgtca aattattgta ttgattgcaa
    12601 atactcccta aaaatcgatg ttgtccagtt gcaaccttga catatttagt ataacgcttt
    12661 ttttgtaaaa cattcctcca tatcctaaac agtcgttgaa acgtcctaaa tgggagcatt
    12721 tttttcgttt aagactgcaa agtgaccatt aagggaaggc gtgaagcgac aagcctgtgg
    12781 ctttaggaac cttaaaaaca ttaaaagcaa gcttctcatt gctattaaca acacaaaaaa
    12841 agcaccagtc tggtcctcac taggtactag ttatcagtca cccccctaaa gttgacaaga
    12901 agccaaaaaa agagaactga ctagctctct tagtgtgcag acaaatctat ctgcttacat
    12961 taatgacaat tctcagaagt gcaaaagaca gctattagcc cttacttgag tacctctcct
    13021 ttgcttggcc tactagagat tctctcaatc aggcgactag tccggattaa aagccagtct
    13081 agccaagccc atgaaattgc tgatagagct cttggcgatt caccttatag tctttggcga
    13141 ttgtcttgat cgcctgatta ggcttcatgc cagcagcaat agcctgttga acaagtgcta
    13201 gcagatccaa atcctcagca ggctctgatg cgtcagcttg attggcacct gccacaatca
    13261 atagacactc acccttgagt ggatggtctg ctagataggt caagacctct gaaatctgac
    13321 cacgctggta ttcctcaaaa agcttggtta actctctcac cagcaccacc tggcgatccc
    13381 catagcaggc cagcaggttt gttagcgtat ccttaacacg ataaggagat tcataaaaga
    13441 tttgagtctc tggataatct gccttagtca tcaaaaatgc cctttgctgc ccagcttttc
    13501 ttggcaaaaa gccataaaac agatggggct ggggcgccaa gccactagca atgaggccgg
    13561 taatgcccgc agaagcaccc ggcaaagcaa caacagtaat atctcgatca atagctgctc
    13621 tgactagctc atgaccagga tctgaaatag agggcatacc agcatcggag acctgagcca
    13681 atgaccttcc agccaacaac aggtccagca aatctggaat tttatcataa gcattatgct
    13741 catgaaagct tacctgcttt gtctttatcc caaaatgctt gagcaacaga ccagtatttc
    13801 tcgtatcctc tgcacagata atatccacct cttttagaac attgaccgct ctaaaggtca
    13861 tatcctctag gttaccaata ggggtaggca ccagatagag aacccctgac tctttttctt
    13921 ccttgaagct cttttggatt tgcatgactc tactttctat ctaatagctc tcgacaaaac
    13981 atacactctt catcattttc acgacgttgc ccatagaaaa aattgcagat atgaaagccc
    14041 tcatcataaa tgccctccaa gtggtccttg ccctgcttag aagaggtctt ggccagattt
    14101 tcgtgctcca attgactcaa gcgctcacgt aatttggtgt tttcaagcct aaggatagta
    14161 ttttcctcta cgagtccttg gacctgcttt ttcattgctt caatttcagc taaagtcacc
    14221 atcaggtttt gtgaaaagcc atcaaaagcg tcaaacagtt cttttttatt cactaacttt
    14281 aacctcctct aaagcatagg ttaccaaggc cagctggtcc ttaaagcgaa cctgaatggt
    14341 atctgtaaaa agatcaattc ctgcaacctc acctggtccc tgcgctgttc ttactatagt
    14401 accataatca ggaaattttt tcttactttc ttgataaaaa tcgtcctcat attgtaggca
    14461 gcacagcaag cgaccgcagc agcccaaaga ctttgccgaa tgcaaggaca gcccttgatg
    14521 ttttagcatt ttgattgaga ctggaggaaa ctctcctaaa aagcttgaac agcatagtgg
    14581 gcgaccacag ggacccagcc ctccataaac ccttgcctcc tcacgactat taatctgacg
    14641 cagctcaatc cttgtcttga aataggcagc caaatccttg aggagctggc gaaaatcaac
    14701 acgctcctga gcggtaaagg taatcaaaac ataacgtctc tcaagggaga aaacaatgtc
    14761 aaccaaggtc atgtctaagc catttctgtc aatcatctct gctacttttt gctttgactg
    14821 ggctgctagc tgaaggtttt gctggtaagc cttgtagtcc atgtcattgg caggtctcaa
    14881 aacagagggc atatcctttg gcaggtcgtc cttacaaaag ctttttatcg gagaattgac
    14941 cactgccaat cgactgccct tgccatcaga tatgacaagc ttggtttgca caggaaaggc
    15001 ctgatcggtt tgaacgtacc tgacagagca ggtgtcacaa tatttaattc caatcgtact
    15061 tatcatgaaa tcaccatata ttctaacgta ttttgaaagc tgacattgct ttgccacata
    15121 agtctagcct gataaacagc ctccagatag gtaaaagcat tttgtcgact gtagtccttc
    15181 gccaagatta aggttaaaag agttagtgcc atgtcctgct cctctttttc ctctgctagc
    15241 tgaaccaagc gattaagctc cagataagcc tgttccttat cctgaaacca gatggaaaca
    15301 aaacgctcag cctgcgccat cagctccaac agcctggtgt tttcagaaaa agcggtaagc
    15361 tgctgggcat tggctgctaa tctggctaag aggtctgctt gatgtttcaa aagccccttt
    15421 ttttgggcca gctcagagag gtagtgctca tcttttggaa agtgaaaaac ctgtgtacgg
    15481 ctcttgatcg ttggtaggac ctgattgtca tcattcgtta gtaaaaacat atagcaatcc
    15541 ccttgtggct cttctatata ttttaaaatg ctgttagctg cattgacatg catcttatca
    15601 caatccttaa tgataaaaac ctgccgcctg ccctcatagc cggtctgcga aaaatttgtc
    15661 atcatttctt tgacggtatc agtcttgata agctgaccga caggctctaa gatggtgaca
    15721 tctgaaaagt cattgtgctc aatcagctgg caagcacgac agtgatgaca aggagcattg
    15781 cctctttttt gttcgcaaaa aagagtcttg gctaaaaaaa gagccatgtc aaaattggca
    15841 aaatcacctg aaaagaggta ggcatgattt agacgttttt tttgcaaaat ctcttgaaag
    15901 gcctgataga ccctaggagc cttttgagcc aaatccattc ctaacctcct gctatgcttg
    15961 actgtgtgtg ataatggcag ctaaagccgc tgacacaacg ctttctaagt cctgtgatgc
    16021 atcaatcttg acaatacgct ggggattttc caaagccagc tccagatagc ccttacgaac
    16081 acgctggtgc aaatctaatt gctcaagatc aagacgattg atctctcgct cagtattttg
    16141 tgcaatcctt gccaatccaa gctctgaggg cacatcaaaa tacagggtta aatcagggtc
    16201 aacaccatct gttgcaaaat gattgagcca ttgaatggct tgcttatcca gccctcttcc
    16261 ggcgccttga taagcaactg aactgtcaat aaaacgatcc accaaaacca agtgtcctga
    16321 ctcaagagct ggcatgatct tttcaaccaa atgctgcctt cttgctgcaa tatagagcag
    16381 cagctctgtt ttatcgtcca tggtcgtgtg actgacatct aagatcagct gacgaatctt
    16441 ctcagcaatc gcaacgcctc caggctctct cgttgttaca atggtttgtc ctagagctgc
    16501 ctgtaagagt ggcaccagtc tttccagcac cgttgttttt cctgctccgt ctggaccttc
    16561 aaacgttatt aattttcctc tagtcatctt tattcctttg tttatcgtta cctctatttt
    16621 accaaaattt gcctgaaaaa gcactgccaa ttcattgggc agtgccagat cagaaaaaag
    16681 cctttttgtg ctgcctttta ggcgatagga ataaaaagcc agccctcaaa gcagcagcct
    16741 aagacttgtg cctcacacct caaagcctat gagcagccac tcgataaatg acaatcgtct
    16801 cagctcttat tttctttgcc taagcaagcc agcagggctg atccatcagc tttgagcaat
    16861 tgatgagcta agacatgcta tataagacag gatcaggcct acttagccct gctcaggtag
    16921 ggcttgaggc tctagaggct cacgatgtaa attcccaaca aaatcacaat caatgtcatc
    16981 aaaggctgat accttcacct ctttgacaaa tgttagccga ctaatgtcct ttagcttttc
    17041 ttccatgtcc tctttattga tgtaaataac aaggtatcga gaacgcctgg aatggtagta
    17101 caagtcacca tatttcatca cttttctagc gtctcgattg taatacaggt agataaccag
    17161 cccaattctc tgctgttttt gaaacattta ggtactcttt tcttttatat tttgatacgg
    17221 tccaagctca tgtcgaggtc tatttgtcgc caagggaagt cctgtgtcga caagaatatc
    17281 ctcagacact gcttctgcaa tagctgtcga aatcgtcgcc aaaacctcct gcaaatcaac
    17341 ctgtgccaag cgcagatcag caaccaatgg atgcaggtca agctggcgct tttgatgaag
    17401 taattggcag cgcaacgctc tagcatctgg acacaactta agcaagtcct gcctaagctc
    17461 ataatcctgc ttaagctcct caaataaggc taactcggtc tgtagggcca aatctgcctc
    17521 aaaagccttt ttagccaagg cataggcctg atactggctg cttgtcctaa tatcctgaac
    17581 cagctgctca atagcctttt caatggcaaa caattcttca tttatgatta gcataggtta
    17641 attataccat aattttaagg aagatagccc tctttagcat gcaaaaagcc cctgaaacaa
    17701 tttgtttcag aagctgttaa gctattttac taagctctct aagctagctc attattttcc
    17761 atgatttcat caataaagcc ataggctagg gtttcttctg cgctcatcca ataatcacgc
    17821 tcagcgtcct tatggatttg tttgatcgtt ttaccggcat tttgtgccaa aatcttttcc
    17881 aggcggtgac gtgtctttaa taaatgctca gcagcaatgg ccatatccgt ctgctgcgta
    17941 ccacctcctg tgcctcccat aggctggtga atcatatatt ctgcatttgg aagcataaag
    18001 cgcttgccct ttgcacctga tgaagcaata acggttccca tagaagcagc catacccata
    18061 acaatggttt gcacatctgc cttaataaag ttcatcgtat caacaatagc taaaccagct
    18121 gatacagagc ctcctggggt attcacatag aggtaaatat cttttgtgtt gtcttgggca
    18181 tctaaaaaca agagctgcgc aataacagag tttgccatat tatcctctac tggaccagtc
    18241 agcatgataa tacggtcctt taacagacgt gaataaatgt cataagaacg ctctccacga
    18301 ctggtttgtt caataactac aggaatcata aaaatctcca atctatcgtg actgtctaac
    18361 accactctgc ctcatgcagt gacaggcagt caaacacatc tttttataat gattgacctt
    18421 attataatct cttggtcaaa aaaggtcaaa tgataaactt gcttttaaaa accttccagc
    18481 ctaaactaga aagtcttatt agctttagca ggctagcctc tagcaagcag agcctagcac
    18541 aaccaaagcc tgtagccttt tacttggtac caaataagcg atcaccagca tctccaagac
    18601 caggaacaat gtagccatga tcatttaatc tttcatcaag ggctgcggta taaatgtcaa
    18661 catctgggtg agcctcctga agctttttaa ccccttctgg tgctgctacc agacacacaa
    18721 acttaatatt agcagcccca cgctttttca gtgaatccac tgcaagaata gcagagccgc
    18781 cagtagccag catcggatca acaataaaaa tttggcgctg atcaatatcc tctggcagct
    18841 tcaccaaata ttcaaccggc tccaaggtct cctcgttacg atacataccg atgtgaccaa
    18901 ccttggcagc tggcacaaga ctaagaaagc catccaccat accaatacca gctctaagaa
    18961 tcggaacaat tgctaatttt ttacctgcta actgcttttg aaccgtcttg gcaaccggtg
    19021 tttgaatctc aacatcctct aatggcaagt cacgagaaac ctcgtagccc ataagcattg
    19081 caatttcatt gaccagctct ctaaaatcct tggttgaggt atcctgacga cgcaggattg
    19141 atagcttatg ctgaataagt ggatgcgaaa taacctgaca ttttcccatg atgacgtact
    19201 tccttcttta ttttttacac ttttgctatt ataccaaaaa attgaaaacc ttgcttactt
    19261 ttttcagatc cggttgaaat gataaaagca agaatctgat cagctagctg cctgcttcag
    19321 ctgccttgat cttgggtgtc aaagtcccaa tttttggcga tacctagctg ctctgctgcc
    19381 aattaatttg tccagctgac gcgtcaataa cgtcatgtag gcgtaaacac ccattcccaa
    19441 gccaccaata atcactaagt aaagcaggct agtcaatctg cctgtcggct taaacaaata
    19501 gcccaaaaac cagttagcta gtagcacaat caggcccatc aatgctgtct caatcaccgt
    19561 tagtaatata cgcttatgca gcagcttacg gttaaatcgt gtgacctgat gtagacgacg
    19621 gtacatgaga tagataggca ctagcaagcc aagggtcgta gctaacaaag gaccataagc
    19681 atgaaacaga tagatcaaag gaacctgcaa aaccagcttg acaaaaacac cataagcaaa
    19741 ataatagatg gccttacggt tttcaaacag ggcctgcagc atcggagaaa aaagcgtata
    19801 caaggccatc aatagggtaa ggcaaagcac agcaacaaac agcctaacag cctgtccctc
    19861 gctactaccg taaaaaaccg tataaagagg ccttgccagt ataatagctc ctgtcagagc
    19921 aggcaataaa aacatcagca gcatttcaat gttgttaatg atcaggcgcc ctgctgctcg
    19981 catgtccttt ttaatgtaat tttctgtcaa taaggcaata ccaacactac caattgaagc
    20041 ggctactgca atgagcacca tggtgatttt agcagggttg gcgttaaaat acccaaacag
    20101 cacccagagc tgagaacgcg tgtagctggt aaacagagtc atcgtattga caaaggtcca
    20161 ctgatcaagg agctgaaagg cctgaatcgc acttcctgta ataataaagg gaatcgactc
    20221 ctttaacgtt tcaataagca agcccttgat gtcaatagga atcgcatgct ctgtcttggt
    20281 aaaaatagcc tttaaaaggc cctgcgtcca gaaataataa aagagcaccg ccatactggc
    20341 tatcattcca ataaaagcag caaaggtgga ctgcgtaaca gctgcaatat agtccttaga
    20401 ccccattttc atgatgaaaa aggttgttag aagcatccag atcacacgaa ccagctgctc
    20461 agcaatttgg ctaagagcat agggcttaat ctccttatag ccctgaaaaa tccccctaat
    20521 cacgctcatc actggaaaaa caaaaacagc taatgataag ctatgcataa tcgggacaag
    20581 ggtctcatca ccaccggaca agcgagcaaa gagcggagat cccagataca tcagcactga
    20641 gaaaatcaag cctaatacca gcataacctt tagagtgctt cgaatgagct gatagctatg
    20701 ctcttgctgt cccatcgagt tgtacttagc gacctgctta gcaatggcaa catttagccc
    20761 tgttgtcgaa atcaacaaaa aataggcata cacattgtat cccatattaa agagcgcatt
    20821 tgcctgtatc gcatactgcc ccatccatat gtaccatgga ataatatata gaacgcctaa
    20881 aagtcggcta ataaaattac ctgcggtgga ccaggctgct ccctgaacca tcagctgttc
    20941 ttgtgtcaat tgtttttttt ctgtcgacat atccgttctt cctagttttt atagctttat
    21001 tataaacttt tgcttgtgac ttgtaaaaca agaacattaa ggataaaata aggctatgat
    21061 aacaattgag cacttattaa ccattttaaa aaaggaccat aatttccgag aggttcttga
    21121 tcaagacggc taccacttta actatagcgg tctacagttt gacagcctta gctacgacag
    21181 cagacaagca gatgagcaga cgctcttttt tgctaaggga tcagctttta aggctgactt
    21241 tttgagacag gccattgcca agggactaag actctatgtt tcagagattg actatcaggt
    21301 agggatccct gttattcttg ttaacaatat taagcacgct atgagcctag ctgcgatggc
    21361 cttttatgat tacccacaaa ataagctcaa gctattagcc ttcaccggaa caaagggcaa
    21421 gacaactgct gcctactttg cctatcatat gctaaaggaa tctcataagc ctgccctgct
    21481 ctctacaatg aacacgacct tagatggcca acactttttt aaatcgcagt taaccacacc
    21541 tgaaagtctt gatttatttg cgatgatggc tcagtgtgtg gctaatggca tgacgcattt
    21601 ggtgatggag gtctctagtc aagcctactt ggtcgggcgt atctacggct taacctttga
    21661 tgtcggtgtc tttcttaata ttagccccga tcacatcgga ccaatcgagc acccaagctt
    21721 tgaggattat ttttaccata agcggctctt aatggaaaat agccgagctg ttgtggtcaa
    21781 tagcggtatg gagcatttta atatcctagc agagcaggtg gctgataagc ctcatgattt
    21841 ttatggcaaa ggggcttgca ataggctgct gcagcggcag gccttctcat ttcaagcagc
    21901 cggcaaggta gctggagact atgcgattca attaattggc agcttcaatc aagaaaatgc
    21961 tatggctgct ggactagcct gtcttcgact gggggcaagc ctagaggata tccgccaagg
    22021 cattgctaag acaaacgtcc ctggccgcat ggaggtctta accatgacca atcaggccaa
    22081 ggtatttgtt gattatgcac ataacggtga tagccttgaa aagctcctat ctgttgtcga
    22141 agagtaccag aaaggccaga tttacttgat tctaggagca ccgggcaata aaggcgagag
    22201 ccgtcgggct gattttgggc aagtcatcaa ccagcacccc aatgttcgta ttattctgac
    22261 tgctgatgat cctaattttg aggacccaca gctgatttca gaggagattg ctagctatat
    22321 tcaccgcgag gttgatatta tcattgaccg taaagaagca atcaagactg gtatggagcg
    22381 ctgtcagaat gagcaggatg cactcattat tgctggcaag ggggctgatg cttatcagat
    22441 tgtcaaggga caaaagactg cctatgcagg tgatttagcg attgcaaaga gctacctata
    22501 gactggtcta acaggctaaa cagtaataat tcttaagatt actgataatg attctaagct
    22561 ggctcctttt ttagcataaa ctcagtaatt agattctgaa aggctttttt aggccttttt
    22621 tctatgctat aatgggatag cttttaagag aaagcgcact attatagtca gaccaaaaaa
    22681 gcgactagca tttcataggc tatcagcccc ttagaatttt gctagctggc tttgcttgac
    22741 tattagaaag gagaaaaacc atgtcaacaa tcagtgctga gaggatttca gctggctatg
    22801 atcaatcgct tatcatcagc aacttatctg tcactattcc cgaaggaaag gtaacaacca
    22861 tcatcggtgc taatggctgt gggaagtcaa cccttttaaa gactctggca cgactattgc
    22921 cactcaaagc agggcaggtt ctcttagatg gacaagccat tgctagacta gcaaccaagg
    22981 acgttgccag aacactagca gttttacctc agctgcaaga agctactaca gctactgtct
    23041 atgagctggt ttcttatggg cgttatcccc accaatccta cctaggacaa ctcagtcaag
    23101 ctgataagga taagatttgc tgggcaatgg aggtcacaag catggcaccc tatgctcatc
    23161 aggctgttga tgccctgtca ggcggccaac gtcaaagggc ctggattgct atggccttag
    23221 cacaggatac tgatattatt tttctagatg agccaacaac ctacttagat atgaatcatc
    23281 agctcgatat tttagaatta ctaaaggagc tcaatcaggt ctctggaaaa acaatcgtga
    23341 tggtccttca tgatttaaat ctttcagcac gctactcgga tcatctgatc gccatgaaaa
    23401 atggacatat caaatattct ggagaggtca accaggtgat gacgccagag atgattcaag
    23461 acatttttca agtaaaggct cagctcgtca ctgatcctct ctatcattgc cctacattgc
    23521 tgacctatca gctgatataa atttattcta ggagaataga atacatgaaa aaactactgc
    23581 ttattttaac tgtttttgtg acagctttta cattagtcgc ctgctcaagt caaagcaagc
    23641 aacaagaaag caccagcaaa gcaagcctat cccacaagcc aaaaattgct ggagtgacct
    23701 attatggtga cattcctgtc aagccaaagc gcgtggttag cttagcagct acatatactg
    23761 gttacttggc aaaattagac cttcatctgg tcggtgtcac ctcctacgac aaaaagaacc
    23821 ctgttttaac aaaaagcatt actcaagcca agcaggtggc agctactgac ctagaggcta
    23881 ttacagcact agagcctgat ctcattgttg ttggctcaac agaagaaaac attgaccagc
    23941 tagcaaaaat cgcaccacta atctccattg aataccgcaa gcgtgattat ttgcaggtgt
    24001 tttctgattt tggccgtatt tttaacaagg aaaaggaaac tgaccaatgg ttggccgact
    24061 ggaaacaaaa aacaagtgac tatgaaaaag aaataaaaca agtcaccgga tcagctgcta
    24121 cctttacaat catggggctc tatgaaaagg aaatttacct ttttggtaag gactggggaa
    24181 gaggtggtga aattattcat caggccttac attatgatgc tcccgaaaag gtgaaaaaag
    24241 aggtgtttaa gcagggctat ctgtccttat cacaggaggt tctaccagat tatattggtg
    24301 attatgtgat tgttgctgct gaggatgacc aaaccggctc agccttatat gagagcgacc
    24361 tttggcagca gatccctgct gtgaccaaca atcatgtcat caaggtcaac gctaatgtct
    24421 tttacttcac agacccactg tcactggagc accagcttga ggttctaaaa aaggctatcc
    24481 tctcaactgg tgcaagtcaa taaaaactta agatgacagc tcaacatcat actaagccta
    24541 aactagctaa agcagctcct ccttggctga tcttaacctt tatcagctta actctagtgc
    24601 ttgccattta ctgcagtctg aggtttgggg ctgtgtcact atcacatcag gagctctatc
    24661 atattctact tggaaagcag gaccagggtc aaaaggccag cattattttg gacattcgcc
    24721 tgccccgctt gattttagca gctctagttg gtgctgcact tgctgtttca ggagctatca
    24781 tgcaaggcat taccagaaat cccattgccg agcctggctt actgggaatc aactctggag
    24841 ctgggctggc attagtcatc ggctatgctt tttcccctca tcttcattat tcgacaatta
    24901 tattactttc cttgctaggg tcactcttag cgaccctatt aattctcagc ctagcctatc
    24961 aagctggtaa gggctacact caaatgaggc ttattttagc aggagcgatg atatctatgc
    25021 tactgtcagc tatcggacaa ggaataacaa cttattgtca cctagccaat gccattattg
    25081 gctggcaggc gggaggattg atcggggtca attggcagat ggttagctat gttgcgccac
    25141 tcatcatctg tggcttagcc ctatcttatc tgctagccta tcatttgacc attttaagct
    25201 taagtcaaga gcaggccaag gccctagggc aacgcacctt cttgattagc cttatcttta
    25261 ttggacttgt gctgcttctg tcttctgctg ctgtagcagt agccggcagc atttcctttg
    25321 tcggcttgat tatccctcat gccatcacat tagtcactgc taaggattac cgctggatcc
    25381 tgccgctagc tactcttctt ggagccagct ttatgctttg ggtagacttt gcctgtcgga
    25441 atatcaatcc cccctatgaa acaccgctat ctgctttgat cagctttatt gggctgccct
    25501 gctttttatg gctagttaga aaaggaggtc gcttttgaca gctactaaaa gacacgtccc
    25561 attatttcta ggactaatct ctggactggt ctgtttgatg attatttcct tgtctattgg
    25621 ggaatctagc atgtcaccat tggaggtcgt cagggtgctt tttggtaaat ccactgctga
    25681 tatggccttg atcatcacca acattagact cccaagaatt ttagctgcct gtatcggtgg
    25741 cggctcactg gccctttctg gcttaatgct gcaaagctta acgcgaaatc atctggcaga
    25801 ttctggcata ctaggcatta atgctggtgc tggtatggct attacccttg tcatatccta
    25861 cagcactagt aacagtctga ccagcaggca agggctgccg cttatgacca tatccggggc
    25921 aatggcaacc attgtcttgg tctacctgct ctcacttcgt catggccata ttgatcctat
    25981 tcggctgatt gtcactggcg tagggctatc aaccatgcta tctagcctga tgattgcctt
    26041 tgtcggcaat gtgaaccgtt ataaggtgga ttatgtgatt cattggctaa gcgggcagct
    26101 aacaggcgat gattggtcca agctaagcat tgttgctccc ttattgggga tcacttggct
    26161 gctagccttt agtcaagcct ataagctcaa catcatggca ttaaatgatg aagcaagcat
    26221 ggctctaggc ttcaagctcc atcagtaccg taccattgtt cttgcactat ctgcgattct
    26281 ctcagcccta agtgttattt tggtcggaaa catcaccttt attggtctga tagcaggcca
    26341 taccagcaaa cgactagtgg gagctgatca ccgattaagc ctgcctgtca gccttttcat
    26401 cggcatgatt ctgcttctct tggctgacac tatcggacga gtctatctcg tcggcagcaa
    26461 tataccaacc ggtattcttg tctcaattat tggtgcatcc tattttctct atctgatggt
    26521 caaaatgaca taagagcctc tgctgcatag cttaaagggc tcagcaagca taaatggctt
    26581 agactcaact gttttacagt gtgggtctaa gccatttttt attcatcaag tcaactctta
    26641 atcagcgtag aaaatcagct gctccttatc aaaagccagc ttcaggcagt atttagtggc
    26701 ctctactttt tcaatatagc ctagaagctc caaggcattc acaaaaatat ctgtccgctt
    26761 ttgcataaca atctcttttc tagcaaattt tagaagaaag ctggtcatgt acttcaaggc
    26821 atagtcctga ttcacatcac ctaatagggc atagagcctt aattgctcat cagatagggc
    26881 ttcccctctt cttaagcggt aaaaataatt ggcaagcgtc agcttatctc ggtcaatggt
    26941 tgttttttcc ttgatcaaaa cctgattggt ctgattagac agcactgtct caaacaccaa
    27001 ggccatcaaa gcttcatata gatctgatgc cctatccaca aagattagat cttctaatgt
    27061 cacctgctgc aggtcatcta gcaagggcag acacagatag tagcgtctgt tttttcgaca
    27121 gatatagcca gcctgaatgt aagcttcaag cgccttatca atccccttaa catgagaaaa
    27181 ggcctgctta atgtgacgca gggttacgtc atcatgctga ttgaggtaat gaataaggtc
    27241 ttgaaaaaaa ggctgacgcg ttaatttatc agggttaaaa atggtaatca tactactatt
    27301 atagcaaaaa gaccaaaggg ctgctgataa aaatcaacac ccctctacag gcaagctcta
    27361 tgctccaaag ctttcagtta attgagggac aacctgcttt ttacgagata cagcacctgc
    27421 taggaaagca tgattatcct caagcttaaa gctaaaggct gcctcaacct tatccatatt
    27481 cgcaccaagc gccaaaatct ctgaatttga attaacaata tctgtaatca tcaagacaaa
    27541 atcagaatag ccctcacttg ccatcacctc tctaatagcg gcctcaatag cctccttgcg
    27601 ctctaacacc tctgcaatgt caacggtatt gacctgggct acacgaactg cgttgccatt
    27661 taattcaaag gtcttagcat caatatcaat caattctgct tctgatttac ttgcaaggtt
    27721 tgttccggcc tttagcatag ccataccgta ttcctctagc ttaactcctg ctaactctgc
    27781 taattccgca gcaacacgat gatctgaagc atgcgttgtt ggtgatttta acagcaaggt
    27841 atcagaaatc aagccagaca aaagcatgcc tgcaatgtcc tttggcacat caaccctatt
    27901 ttccttgaac aggcggtaaa caatagatga ggcagagcca acaggttcga cacgcatata
    27961 aagcggattt gctgtctcaa aattagccac ccgatggtgg tcaacaatac catacacctc
    28021 aacctcacga atatccgaaa tagactgtgg aaattcgtta tggtctgtta gaataacatg
    28081 actagcaccc tctgcttttg ctgatgtcac cactcttggt gctgataccc caaaatagtc
    28141 aagggcaaag gctgtttctt catttgggtc acccagagcg actacctccg tatccaaatc
    28201 aaaggctttt tttgctaagt agtcaaaagc atacgatgat gcgatggcat cagtatctgg
    28261 attttgatga ccaaaaacta atagttttga cataaagttt ctacctcatt ctctttattc
    28321 atcttattgt agcagaaata ggctctaaaa tcaaagaaga ttccccagtc acaggccaag
    28381 agtctaaagg gcataagggc acagaatctc aggtattaaa gagtcctgtc aaacacacaa
    28441 gaacaggcaa gccagtccaa aaagcaatgc cttctataat gagctattca gctatttggg
    28501 gacaatacac tgtccttgat tggtttaatg cttcaaggat tactttttgg cacgtgtctg
    28561 agctcgctta aaaacactga aggtctcatc aagccagccg cttcatcagc aaaaaaacgg
    28621 ctctataatt tccatggtgg atttacccac tacagaaatt atagagccca tttacctcgc
    28681 tttgcacatc acacaagaga aaacgagctt cgtctcgtgc ttagttatca gtcacccact
    28741 acagttgaca tggggccaaa aaaagctggg catttcccaa ctctagctta gcctatgatt
    28801 gatgaatacg gttcatgtat tcagtatagg attctgtatg cagcagcttt ttggcattct
    28861 ccacccgctc cttggttggt ggcttaacgc cctcaagctg gtatggaatc cctaactcgc
    28921 gccatttgaa ctctcccatc gtatgataag ggagtacctc aaacttgtcg acatttctca
    28981 aggtcttgac aaacgcatct aagcgtacca agtgatcatc aatgtctgtc aagccaggca
    29041 ccaagacatg gcgaatccag acgggcacct gcctatcaga gaggtagcga gcaaactgca
    29101 ggatattttt attgggctga cgggtgacaa gcttatgctg ctcctcgtca atctccttta
    29161 agtccagcaa aatcaaatca gtaactgcta ataatgtttc taacagctca tggtattcag
    29221 gggttggacg ataggcaaag ccacaggtat ctagcgttgt atggatacct agctttttgg
    29281 cctcagtaaa gagcgcagtg ataaagtcca tttgcagcat agcctcacca cctgacacag
    29341 tgattccacc ctttttcccc caaaagtgcc tatattgcag agcctccttt aggacatcat
    29401 taacggttcg gcgttgagat tgattggttt ccatagccca ggtgtccgga ttatggcaat
    29461 actggcaacg catcttgcag ccctgcaaaa aaatgataaa acgtatcccc ggaccatcaa
    29521 cagaaccaaa gctttctgta gaatgcacca ttccagttac ttgcccataa tctacttcaa
    29581 ccattgtgtc tccttcaccc ttgtaaatgg ttttacgttt tcattatatc atgtttcatc
    29641 aaaaagacta agctcaatgc ctagtcttca gtaatattct gttctatatt agaaatagta
    29701 agtttcaatt tggtgatacg accgtccttt actttgtcat tgaccaaaac cagatgcttt
    29761 tgcttgctat cacaggcaaa gctctctttc tccttttgac ttggaatggt accaatccct
    29821 gtcaaataaa agcccgcgat ggtatcgaca tcatcacttt ctaattctgt gtcaaaatac
    29881 tcgttaaagt cgttgagcgt cattgtccct gtgacaatat aggtgttgtc atcaatgtga
    29941 tgaacaaatt gctcagcctt gtctgtctca tcatcaatct caccaacgat ttcctcaagc
    30001 aaatcctcaa gcgtcaccaa acctgcaacc cctccgtact catcaagtag gatagccatc
    30061 tggttttgag tatttcgcaa ttgcctcaac aaatcatcta caaaaatcgt ttctggtaca
    30121 aagagcggct cctgcagaag ctttctcatg ctgatgtttt caaagccctg acgaaagcct
    30181 gattctaaaa gccttttggt atgaattaag ccgatcacct tgtccttgtc aacatcataa
    30241 actggaatac gagagaagct ctgctttagg atttccttga tattgtctag cgtatcatcg
    30301 ttaatgtcaa tcatgaaggc atctgtcctt ggaaccatca cctcacgcgc catcatctca
    30361 tcaagcgaga aaatcccctg cagcatttca atctcttcgg catcaagcgt tgcctcgctg
    30421 ttagtcagca tgtactcaat ctcatcacgc gtcatgcgct catctgcgtc atcaaaggtc
    30481 attggggtaa tccggctcag taaatttgtc gacgccgata agagccaaac aaagggacta
    30541 accaatttcc ccaagataat gatcactggg gcagaaatca cagcaagctt gtcttttaga
    30601 ttcatagcta tccgcttggg gtataactct cccaaaacaa tcgagacata ggtcaagaac
    30661 accaaagaaa taatgctacc agctgtttga gcggtcgcag aaccacctaa ccagccagaa
    30721 ataacctgcc ctaaagaggc tgacaggctc gcccctgaca agaggctaat aaaggtaata
    30781 ccaacctgaa tggtcgataa aaagttattg ggctgctcta aaacacgcag caagcgatca
    30841 tacctcttat ccccatcggc agccttttgc tccacacgag agcgatttaa ggataccaga
    30901 gccatctcac tggctgagaa aaaggcattt aacaaggtta gaatgactaa caataaaaac
    30961 tgaatcaata aaggctgact cacagggtct tccattaata taactcctaa aacataatat
    31021 actacttcat tatatcacaa ttgtcgccaa agattgctga tttatttctt tttcctgaga
    31081 aatcacagac agtctaagcc ctgacataag gctggctgaa gcttaatcag tagctgctat
    31141 tttttccagc atgattaaaa atggcggctg attcatctga ttgatcggct gatagagcat
    31201 tgctgttacc tggcgctgat tgagctgacc aatatagtcc aaaagctctt ccttctccct
    31261 actaccgcca tcatgaccat aatacaccat gatagcaatc cgtccaccta gctcaagccg
    31321 atcaagtatt ttagctaggg ctaatatggt cgtctcaggc cttgtgatca acgacttatc
    31381 tgcattgggt agatagccca gattaaaaat ggctgcccga atgggctcct taacatattg
    31441 atccacctgc tcgtgtccag ctaaaataag ctctgcatta gtcaagcctt gctgctccaa
    31501 gcgctcttgt gtcttggtca gtgcctgctg ctgcacatca aaagcataaa ccctttgtga
    31561 cagacttgct aaaaaggcag tgtcatagcc atttcccata gtagcatcaa cagcaatact
    31621 ctgcttatcc aaaacttctt ttaaaaattc atgtgataca tgaataggac gctttatcat
    31681 cttatcctcc taagcaaata cttcaaatgc cgcgatacca tctagtatgt ctaagtcaat
    31741 atgccttcgg ccgtaacaat ctagcacata atctttatac cgatctgttt ttagattgaa
    31801 ttgaagcgac cagatcagcc aaaaaagatc aatatgtcga tcgctttttc ctgcctcccc
    31861 ccaatcaatc atggactgaa attgccaccg atccaagatc atatttggca aacaaaaatc
    31921 cccatgaatc agagtttcat gctgtaacaa gagcttaagc tcctgaatcc gcctgtaagc
    31981 ctcctcctgg gactgaaacc gttgctgagg cggtaaaaag cactgattga accgcccttg
    32041 gtgataacca gcctcagcag cttcgatata ggctagcgtt ttgtcagcta caggaaaatc
    32101 agacaaagac aggctatgca gctttagcat atgatcaact aagatacgac ataagcgctt
    32161 gggatcggac aaatattcaa tatgactggc gtcctctcct gctacctttg cggttaaaag
    32221 ccaatcctga tcaccgctga tataatcaag cacctctgtt gctaagccct tactatgaca
    32281 ataccgagtt agggcggcct ccttggcaag cctaccttta gcggctgttt ttagaaaata
    32341 gccctgccct ttatcaatag cataaacacg tgcctctgcc gagctactgc tatcataaac
    32401 caaactgttt tgtaacagtt tttttaaaac aggtggtagg ctcagctcct ctcctgctat
    32461 caatctttgt ttcattgctt cccccgatta tcccttaagc ttacagccct gccagctatt
    32521 tcttctttcc atttctaggt caatcgcatt caaaacctcc catttattca ggctccacat
    32581 gggaccaatc agcatgtccc taggcgcatc acctgtgatg cgatgaataa tgatatgctc
    32641 aggtatgatt tctagctgat cacagataat cgatacatag tccttctgac tcaagagctg
    32701 caagcgtccc tcatgatagt ctctttgcat acgcgtattg gtcatcaggt gcagcaaatg
    32761 cagcttaatg ccttgaatat cattgtctgt gacacagcgt ctaacgtttt cgatcatcat
    32821 ctcatgggtt tcaccaggca agccattaat caagtgagac acaatgttaa tgttagggta
    32881 ctgcctcaga cgctgaaccg tttccttata caagtcataa gaatgcgccc gattaatcag
    32941 ctgggaggtg gcttcataag ttgtttgcag cccaagctcc actgtcacat gcatgcgctc
    33001 tgatagctca gccaaataag caatcgtctc atctggcaaa caatcaggcc ttgttccgat
    33061 attgatacca acaacgccag gctcattgat tgcttgctca tagcgctcgc gaataacctc
    33121 tagcttatca tgcgtattgg taaaattttg aaaataaacc aaatactgat tgacctcagg
    33181 ccacttgcga tgcataaaat caatttcttt gtaaaattgt tccctgatag gtgcatcagg
    33241 cgccacaatc gcatcacctg agccagaaac ggtacaaaag gtgcagccac catgagcaac
    33301 tgtcccatca cgattaggac agtcaaagcc agcatcaatg ggcaccttga aaattttagc
    33361 accaaataaa cgacgataat actcatttaa ggtctgatat ctttttgtca tgcctctatt
    33421 gtagcacaaa tcccccgatt aacagcagaa gatctcaatt ggctgctact tctctgattg
    33481 atgagccaaa gcaaggcaac taaaaaggat tgaagaagac ctctggaaga gacctgcctt
    33541 caatcactag cttttctaga actgatctgt aacgcgccat acagctgact gatcactgga
    33601 tttacttttg ctttagctga aaacgccatt caaagcgctt ttgatcataa aaaggataaa
    33661 gcagctgaag tatgccaaag cctaaggcat agccagccaa cacatcgcta ggataatgca
    33721 ctcccagata aatgcgtgac aagcctatca gcaaaatcaa ggccaaaagg gctatatcaa
    33781 ccagccagcg taaggaggct gactgcaatc tttgatggca aataatcagc agacttccaa
    33841 taatcaaaag gcttcccatc gaatggccac tcggaaaaga atagccagaa gcatgcacca
    33901 aatgctcaat gctgggtctt ggtctttgat acaagagctt tagcacccaa atcaaaaggg
    33961 ccgcaaaaac accatttgat aggacaaata aggcctcagc tctccagctc aaggccaata
    34021 aagccagcac agcaacaaca acaatcactg cctgtgtact aacatttcca gctacagtga
    34081 tccctttaaa aaactgggtt agcccttcag gcagatgacc tcttagggct aaccgaagct
    34141 gactatcaaa agacgttagg tcttcgggaa aaaatttaac aatatagcca agcaccacaa
    34201 atagtagcat agcaaaggaa gacaatagca gatgttgttg tttatgtttc atgatatgaa
    34261 ttcggatatc tctctaaaat tggtttacct gcaatataca cgaaataaaa gacaattgca
    34321 aatattagcc cctccaaaag gttgaaagga atgaccattg taaatatgta gcgagcagta
    34381 ccaataaaag ctttaatatc aaagccagca aacttggcat ataagggaat agcaaagaca
    34441 tagttcatga caaccatacc aagcgttaac agccctgtcc ccacaagact agctagtaca
    34501 taggtgacca gccctttctg acgatgccaa atcaaggcaa aggcagtgat aaaaagcgca
    34561 actgctataa cattcatcgg tataccaatc aaatcattaa cgccatgatt gtttaaggct
    34621 agtctaagca aggtcctcac cgctaaaatc aagttagctt gctttagatc catcaagacc
    34681 aagcctaaca aaatcggaat gatactaaaa tcaatcttta aaaagctggc tcctggaata
    34741 atggaaaacc ccacaaacat caggcaaaag gatatggctg aaagaatggc aaccatcacc
    34801 agttgatgtg tttttgacat aaaaaattcc tccaattttg acaaattgaa agaagctcct
    34861 tcgtatgagc aggcaaaaag tcaactcaaa aacccggtct tctctcttcc agactttact
    34921 gtcggttgtg gaatcacacc acatcagctt gcgctcgcgg acttctagct gcactagtca
    34981 ccgccggtcg ggaattacac cctgccctga agacacttat agcatagcaa atttaaacct
    35041 atagcgcaag acattttttt gaagcctagc ttttccaaca aacacaagac atcaggcaaa
    35101 aaagctagat gaaagcaaca gcaagaaaaa tcactttgag gctacaaagc tctctacgag
    35161 gtaggccacc ctgtgacatg gcactagcct agctcaaggc aaaaaagagc agactagaag
    35221 aaacctccaa taacctgctc tggtattact accgttgtcc cctttacggt catagacaca
    35281 cctaaccaat gaaaactcca atcagagttt tcagattgaa gaaaaagtcc attttagacg
    35341 gttttcttca atctttttct tttaatcaaa aaaacaaaag aagtctgaaa aatactgtaa
    35401 tatcagcatt tcccagagtt ttcatgatat gatagtcaat ttctaaatgt tcaatttttc
    35461 tatcgctgat agggtttgcc tacattctga actccaatcg gagttttttc tttttggctt
    35521 tagaaaacct ttggcacagc taatggctcc aaactggtga tggtgattca tcagccctct
    35581 agggcagcgc ctttgcttct tactgctgct cacaccgcaa gctctagcag tgtagtgact
    35641 gtagctggta ggacagtaag tccttcttgt ctcacatcag gctgctatag cccctgttct
    35701 gtgtcttgat cgc
//
LOCUS       DARYYD010000020        32918 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.020, whole genome shotgun sequence.
ACCESSION   DARYYD010000020 DARYYD010000000
VERSION     DARYYD010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32918
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.020"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(310..909)
                     /locus_tag="TV188_000879"
     CDS             complement(310..909)
                     /locus_tag="TV188_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1534253.1"
                     /translation="MKRRKARRSHREASSWLAAGIVLGSMLLSLWTLASAKDHLKPHA
                     NSSTMLFVSKISHSAQAVAQRNKLYASVMMAQAILESANGQSKLSQEPYYNFFGIKGS
                     YKGKSVILPTLEDDGQGNLYLIDASFRSYGSLTACFEDYARVLSDPLYRPTHRGIHTS
                     YQQATASLTGTYATDTSYGEKLNRIIGDYQLTYFDAPIR"
     gene            complement(1487..3433)
                     /locus_tag="TV188_000880"
     CDS             complement(1487..3433)
                     /locus_tag="TV188_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1534254.1"
                     /translation="MKIQDLLRKDIMILDLQAVSKEAAIDEMITELVEHGIVHDFDVF
                     KKSILAREEQTSTGLGDGIAMPHSKNVVVDQPAVLFAKSNKGVDYKSLDGQPTDLFFM
                     IAAPQGANDTHLAALAELSQYLLKDGFADQLRKATSPDEVIAVFDAASDQKEVAFVPT
                     NAQEFIVAVTACTTGIAHTYMAEEALKKQAAQMGVGIKVETNGASGVGNRLTADDIKQ
                     AKGVIIAADKAVEMDRFDGKQLIARPVADGIKKSEELISLILNNAGSVYHAKNGAAEQ
                     AKAAQKTSLGGAFYKHLMSGVSQMLPFVIGGGILIALAFLLDNMLGVPKDQLSNLGSY
                     HEIAAIFKHIGGAAFSFMLPVLAGYIAYSIAEKPGLVAGFVAGAIASSGLAFGKVPFA
                     AGGEASLSLAGVPSGFLGALVGGFLAGGVILALRQVLAGLPRSLEGVKSILLYPLLGV
                     LVTGLLMLLINIPMAAINTALNHFLESLSGSSAVLMGLLVGGMMAVDMGGPVNKAAYV
                     FGTGTLAATVASGGSVVMAAVMAGGMVPPLAVFVATLLFKDKFTKEERESGLTNIIMG
                     LSFITEGAIPFGAADPARAIPSFIAGSALTGALVGLAGVKLIAPHGGIFVIALTSNPF
                     LYLLFVAIGAVVSGILFGALRKKA"
     gene            complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TV188_000881"
     CDS             complement(3430..4341)
                     /gene="pfkB"
                     /locus_tag="TV188_000881"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEL1534255.1"
                     /translation="MIYTVTLNPSIDFIVRIDQLDIGAVNRMVSDDTFAGGKGINVSR
                     ILQRLGIDNTATGFLGGFTGRFIKESLAAESINTDFVTVDQDTRINVKIKSAEETEIN
                     GLGPVISKQQLDHLKAILANVSAEDIVVFAGSAPSSLGNDVYKDLIPLVRQAGAQVVC
                     DFEGQTLLDALAYHPLLVKPNNHELEAIFNVSLNGLDDVETYARKVLDMGAQHVIVSM
                     AGDGALLVTQEATYFAKPIKGQVKNSVGAGDSMVAGFTGAFVKSHSPLEALKWGVACG
                     TATAFSDDLAAIDDIKKTYNEVEVEVR"
     gene            complement(4338..5051)
                     /locus_tag="TV188_000882"
     CDS             complement(4338..5051)
                     /locus_tag="TV188_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1534256.1"
                     /translation="MAKITAENYVALEDLMQLLSSSESTVRRDLDELEREGKLHRVHG
                     GAELFHSLQEELSNQEKSVKNSQIKEIIAQKAAELVFDNDVIFIDAGTTTEFLLPFLQ
                     LKKVTVVTNSIHHATRLVDMAIKTIIIGGYVKQTTDASIGHVALEQIRQMNFDKAFLG
                     INGIDEAFLTTPDMEEAVIKKAVIANAKITYVLADATKLGHVSFVKVAPIDRVEIITE
                     KSSTVMLKKIKEKAKVIAL"
     gene            complement(5486..6409)
                     /locus_tag="TV188_000883"
     CDS             complement(5486..6409)
                     /locus_tag="TV188_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HEL1534257.1"
                     /translation="MLVYIAGSGAMGCRFGYQISKTNNDVILLDNWEAHLQAIKENGL
                     KISGDVEETVKLPIMKPTEATKEADLIILFTKAMQLPQMLTDIKGIIGPETKVLCLLN
                     GLGHEDVIRHYIPEHNILMGVTVWTAGLEGPGQVHLQGVGALNLQSMDPANQEAGHQI
                     ADLLNDAQLNATYDDNVVPNIWRKACVNGTMNSTCALLDCTIGELFASEDGLNMVKEI
                     IHEFVIVGRAEGVELNEEEITAYVMETSVKAAHHYPSMHQDLVQNHRLTEIDFINGAV
                     NTKGEKLGIDTPYCRLITQLVHAKENILKIK"
     gene            complement(6421..7479)
                     /locus_tag="TV188_000884"
     CDS             complement(6421..7479)
                     /locus_tag="TV188_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HEL1534258.1"
                     /translation="MTTTNKETFSSFMNKVLAGTAIAIVVALIPNAILATFLKPLLPN
                     TVAAEFLHIVQVFQFFTPVMAGFLIGQQFKFNPMQQLAVGGAAYIGSGAWAYTEVIQK
                     GVATGTFQLKGIGDLINMMITAALAVLAVKWFGDKFGSLTIILLPIIIGTGVGYIGWK
                     LLPYVSYVTTLIGQGINSFTTLQPILMSILIAIAFALLIVSPISTVAIGLAIGLNGMA
                     AGAASMGIASTTAVLVWATLKVNKSGVPIAIALGAMKMMMPNFLKYPVMAIPMMMTAI
                     VSSLTVPMFNLIGTPASSGFGLVGAVGPIASLAGGSNIVIIIIAWLVIPFGVAFVAHK
                     LCKDILKLYKEDIFVFEG"
     gene            complement(7611..8603)
                     /locus_tag="TV188_000885"
     CDS             complement(7611..8603)
                     /locus_tag="TV188_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEL1534259.1"
                     /translation="MQEKIYDITIIGGGPVGLFAAFYAGLRGMTVKIIESLSELGGQP
                     AVLYPEKVIYDIPAYPALTGAELTQKLIEQLSRFDDRIAVCLKEEVLSFEKADGNFVI
                     QTSKARHYSKAIIVACGNGAFAPRTLGLDNEQLFADHNLFYNVHSLNQFAGKRVVICG
                     GGDSAVDWALALDGLAKSVTLVHRRDAFRAHEHSVELLKNSHVTTLTPFVPLALEGEN
                     GFVNKMTIQKVKSEEEITLELDSLIVSFGFSTSNKNLKHWNLDYKRSSLLVSPLFQTS
                     QEGIFAIGDAAAYEGRVDLIATGFGEAPIAVNQAIKYIYPDRDNRPVHSTALID"
     gene            complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TV188_000886"
     CDS             complement(8603..9334)
                     /gene="trmD"
                     /locus_tag="TV188_000886"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEL1534260.1"
                     /translation="MKIDILTLFPEMFAPLEHSIVGKAKEKGLLDIHYHNFRDHAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDTMDSIQATKPRVILLDPAGKPFHQSYAEELALEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDFVLTGGELAAMTMIDATVRLIPNVLGKQASH
                     QEDSFSSGLLEYPQYTRPYDYRGMKVPDVLMSGHHEHIRLWRMEQSLKKTYLRRPDLL
                     ETYDFSDEEKRIFDKIKSGLSEGEN"
     gene            complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TV188_000887"
     CDS             complement(9324..9842)
                     /gene="rimM"
                     /locus_tag="TV188_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEL1534261.1"
                     /translation="MEYFSVGKIVNTQGLQGEMRVLSVSDFTEERFQKGARLALFDDK
                     DRFVQEVEIASHRKHKQFDIIKFKGMYHINAIEQFKGYSLKIAKENQGKLAEGEFYYH
                     QIIGLEVYEKDQLVGEIKEILQPGANDVWVVKRQSKRDLLLPYIPSVVLCVDIEKHRV
                     DVEIMEGLDDED"
     gene            complement(11117..11356)
                     /locus_tag="TV188_000888"
     CDS             complement(11117..11356)
                     /locus_tag="TV188_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEL1534262.1"
                     /translation="MDTIENLIIAIVKPLISQPDKLTIKIEDTPDFLEYHLDLDAQDI
                     GRVIGKKGRTITAIRSIVYSVPTLGKKVRLVIDEK"
     gene            complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TV188_000889"
     CDS             complement(11366..11638)
                     /gene="rpsP"
                     /locus_tag="TV188_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEL1534263.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRAPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLDWLGKGAQPSDTVRSLLSKAGVMAKFHDQKFSK"
     gene            complement(12069..12686)
                     /locus_tag="TV188_000890"
     CDS             complement(12069..12686)
                     /locus_tag="TV188_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1534264.1"
                     /translation="MSSFGVSHSLLKKLFKILGGLSILFSVMLVVYLIRQLDIINNPK
                     ALAHLIKDHLLIGAICFFILQIVQVVVPIIPGGVTTVVGFLAFGPILGFMLNVFGICI
                     GSSILFQLVRRYGKPFILLFLSMEQLQFYEKKLSTKLFERFFILNMISPLAPADALIM
                     ITGLSQMTYKRFLLIILICRPISILTFSYFWIYGGEFLKHILMHY"
     gene            complement(12679..13902)
                     /locus_tag="TV188_000891"
     CDS             complement(12679..13902)
                     /locus_tag="TV188_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1534265.1"
                     /translation="MENWKFALSSIWGHKLRSILTMLGIIIGVAAVVIIMGLGAAMTK
                     RVTDSFSNDQKEVQLYFKAKGDEDNPYAAFAAHENEQEVKPEWLEQIVKAIDGVDSYY
                     YTNNSTSTISFEKKKMDNVAITGVSQDYFKVKKYDIVAGRTLNSKDYKNFSRIILLDT
                     VLADELFGKGNYEQALNKVVSLDSKDYLVVGVYKTDQEVVSFAGGISGGAIMANTQVA
                     SEFHVKEIGSVYLYIGDVKRSLELGNQAAAMLTTLSHVKEGEYAVPDNSQIINDINAQ
                     FSIMTTVVGSIAGISLLVGGIGVMNIMLVSVTERTREIGLRKALGATRLKILSQFLIE
                     SVVLTLIGGLLGLLLAQMCVGVLGNAMQLKGAAVSLDVAAVAIIFSASIGIIFGLLPA
                     NKASKLDPIEALRYE"
     gene            complement(13914..14624)
                     /locus_tag="TV188_000892"
     CDS             complement(13914..14624)
                     /locus_tag="TV188_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534266.1"
                     /translation="MPDEKKELIQLKSIVKSYQNGDQELQVLKGVDLTVYEGEFVAIM
                     GPSGSGKSTLMNIIGLLDRPTSGDYRLNGTQVEILNDRKLAQVRNEEIGFVFQQFFLL
                     AKLNALQNVELPLIYAGVGVSKRRELAKQFLEKVELGMRMKHLPSELSGGQKQRVAIA
                     RALVNNPSIILADEPTGALDTKTGEQIMRLLTELNKEGKTIIMVTHEPEIADFATRKI
                     VIRDGEITADTTESVRID"
     gene            complement(14624..15886)
                     /locus_tag="TV188_000893"
     CDS             complement(14624..15886)
                     /locus_tag="TV188_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEL1534267.1"
                     /translation="MSKRGKIKLSTKTKGIIAGAVALTVVVIGGVLWKQQQDTISDQN
                     IKLPYSAVNVTEGTIASSTLLSGTVKALSEEYVYFDASKGSDATVTVKVGDQVTQGQQ
                     LVQYNTTVPQAAYDTAVRNLNKIGRQINHLKTYGVPAATTETSKDEETGQETTTTIQP
                     SAQQNASYAQQLQDLNDSYADAQAEVNKAQQALNETVVVSGVSGTVVEVNNDIDPSSK
                     NSQTLVHVATEGKLQVKGTLTEYDLANIKVGQAVKIKSKVYADQEWTGKISYVSNYPT
                     DANAGGSTAGGSGSSSSTGATYDYKIDITSPLNQLKQGFTVSVEVINEAKHALVPVTA
                     IVNKGKKHFVWVYDDSTAKAKKVEVTLGNADAERQEVSAGLKVGDIVIANPDKNIKEG
                     EKLEDVISADTKASKDSKKSSKESEVIK"
     gene            complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TV188_000894"
     CDS             complement(16201..19377)
                     /gene="carB"
                     /locus_tag="TV188_000894"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEL1534268.1"
                     /translation="MAKRTDIKKIMVIGSGPIVIGQAAEFDYAGTQACLALKEEGYQV
                     VLVNSNPATIMTDKEVADKVYIEPLTLAFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     SKAGILQELGVELLGTTLSAIDQAEDRDLFKQLMKELGEPIPESEIVTTVEAAIGFAN
                     AIGYPVIVRPAFTLGGTGGGICSNEEVLRDIVENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDAADNALVVCSMENFDPVGIHTGDSIVFAPTQTLSDVENQLLRDASLRIIRALK
                     IEGGCNVQLALDPNSFSYYVIEVNPRVSRSSALASKATGYPIAKIAAKIAVGLRLDDM
                     LNPVTGTTYAMFEPALDYVVAKLPRFPFDKFERGERRLGTQMKATGEVMAIGRRIEEC
                     LLKACRSLEIGVHHNELKGLDTISDHELVAHIVRAQDDRLFYLSEALRRGYSIEELAG
                     LTKIDLFFLDKLRHIVELEQDLIKKPVDIDLLIEAKRYGFSDQKIAELWQTDAASIRR
                     LRRAYRVLPVYKMVDTCAAEFDSQTPYFYSTYEWENESIKSEKESVIVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEEVMNVIEL
                     EQPKGVILQFGGQTAINLAEQLTKAGVPILGTQLEDLDCAEDRELFEKALKELGIPQP
                     PGKTATNEAEALEAARAIGFPVLVRPSYVLGGRAMEIVENENDLRSYMKTAVKASPEH
                     PVLIDSYILGKECEVDAISDGQSVLIPGIMEHIERAGVHSGDSMAVYPPQHLSKQVQD
                     KIVDYTKRLAIGLNCIGMMNIQFVIQNEQVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQTLKDLGYQDGLYPESSLVHIKAPVFSFAKLAKVDSLLGPEMKSTGEVMGSD
                     LTLEKALYKAFEASYLHMPEYGTIVFTIADDHKSEALILARRFSAIGYQIMATEGTAA
                     FFADQGLDSQLVGKIGDNAHDIPALLRKGQIQAIINTVGTKRVTDKDGQMIRSSAIEQ
                     GVPLFTALDTAVAMLRVLESRTFSIEAI"
     gene            complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TV188_000895"
     CDS             complement(19795..20886)
                     /gene="carA"
                     /locus_tag="TV188_000895"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEL1534269.1"
                     /translation="MAKRLLILEDGTIFEGKPFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQLLVFTYPLVGNYGINRDDYESIAPTCKGVIVSEVSRIASNWRQQMTLDEFLK
                     HKGIPGISGIDTRALTKIIRQHGTMKATMADDGDTLEHLKDQLRATVLPTNGIEQVST
                     KTAYPAPGVGKNIVLVDFGLKHSILRELSKRQCQMTIVPFDITAEEILQLNPDGLMLS
                     NGPGNPEDLPEALEMIRGVQGKIPIFGICMGHQLLSLANGAKTFKMPFGHRGFNHAVR
                     EIATGRIDFTSQNHGYAVERDSLPDCLMVTHEEINDKTVEGVRHRHVPAFSVQFHPDA
                     APGPHDASYLFDEFLDMIDAWQLEQQGKC"
     gene            complement(20909..21844)
                     /locus_tag="TV188_000896"
     CDS             complement(20909..21844)
                     /locus_tag="TV188_000896"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEL1534270.1"
                     /translation="MSVVNNRVALKHLVSMEHLTNEEVLGLISRGSEYKAGKVAIKDN
                     SRHFAANLFFENSTRTHKSFEVAENKLGLRVLDFNADTSAVNKGETLYDTVLTMSALG
                     TEICVIRHPEDDYYQQLIDSPTITASIVNGGDGSGQHPSQCLLDLLTIYEEFGHFDGL
                     KIAIAGDLTHSRVAKSNMQILKRLGAELYFYGPEQWYSSEFDSYGRYMAIDHIIDQLD
                     VLMLLRVQHERHDGSQSFSKEDYHRQFGLTEERYRRLKDSAIIMHPAPVNRDVEIADH
                     LVEAPKARIVAQMANGVFVRMAIIEAILNGRNDKV"
     gene            complement(21902..23161)
                     /locus_tag="TV188_000897"
     CDS             complement(21902..23161)
                     /locus_tag="TV188_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEL1534271.1"
                     /translation="MKDVIYDVEEVPKAGILLGLSFQHLFAMFGATVLVPILVGIDPS
                     VALLSSGLGTLAHLSVTTFKIPAYMGSSFAYIAAMQMLMKTDGIGAVAQGAITGGLVY
                     LVVALVVKAIGNEWIDKILPPVVVGPIVMVIGLSLASTAVSDVMLKDGKYNLLYLLIG
                     LVTLLAIIFFNIYGKGIVAIIPILLGLLVGYLFAILVGMVTGQSIVDFTQVAKAQWLS
                     VPAVAIPFLTYDITLYPSAILTMAPIAFVTMTEHFGHIMVLNSLTKRDYFKDPGLEKT
                     LTGDGLAQVIAGFLGAPPVTSYGENIGVMALNKIFSVYVIAGAAVIAGLLSFVGKVSA
                     LIQSIPTPVIGGISIALFGVIASSGLKILIEAKVDMDNKKNLLIASVILVSGIGGLML
                     QINGLQISGVAFSTLLGIILYQLLPEN"
     gene            complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TV188_000898"
     CDS             complement(23177..23698)
                     /gene="pyrR"
                     /locus_tag="TV188_000898"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEL1534272.1"
                     /translation="MKSKVIVDELTMKRAITRITYEIIERNKQLDNVVLVGIKTRGVY
                     LARRIQERLEQLESLHLAVGELDTKPFRDDMRVEEDTTSMPVDITGKDIILVDDVLYT
                     GRTIRAAIDNLVSLGRPGRVSLAVLVDRGHRELPIRADYVGKNIPTSKTEEIVVEVVE
                     VDGQDRISIVDPG"
     gene            24060..24674
                     /locus_tag="TV188_000899"
     CDS             24060..24674
                     /locus_tag="TV188_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1534273.1"
                     /translation="MNDITRKINHKQLIQITTILGIIVTIVILFYLQQHPNLFAVGGP
                     FQTYLMELGILAPCLFILLQIIQVVYPIIPGGLTCVLGHVVFGPFWGFLYNTLGIFIG
                     SLLSFMLARKYGEQFAKAFVSDDTYNKYIPYLNKGKYFERFLITAFILPGFPDDFLCM
                     VAGLSSMSIKTFTSIFLISKPITLYIYTLLAYQGIQIVGQVLQS"
     gene            complement(24755..25645)
                     /locus_tag="TV188_000900"
     CDS             complement(24755..25645)
                     /locus_tag="TV188_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1534274.1"
                     /translation="MEIKITESGHRLDKALADLTPLSRSQANDQIKQKRVLVNGLPKK
                     AKYIVQVGDCISYHIPEESSLDYQAQDIPLDIVYQDDVLAIINKPQGMVVHPSAGHST
                     GTLVNALLYHIKDLSSINGVIRPGIVHRIDKDTSGLLMVAKTDKAHQLLADELKAKKS
                     LRKYVAIVHGNLPKDRGVIEAPIGRSEKDRKKQTVTAKGKEALTLFKVLERFGHYTFV
                     ELQLETGRTHQIRVHMAYIGHPLAGDPLYGPRKTLAGKGQFLHAQTLGLTHPVTGEEL
                     VFTVEPPEIFQRTLEQLRQG"
     gene            complement(25635..26093)
                     /locus_tag="TV188_000901"
     CDS             complement(25635..26093)
                     /locus_tag="TV188_000901"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEL1534275.1"
                     /translation="MKRISFIMAAIVLMILDQLSKWWTVTHIELGQVKPFIPGLVSLT
                     YLQNRGAAFSILQNQQWFFTIITVLVVGYAIYYVLKHPKASFWLQLSLLLIISGGLGN
                     FIDRLRLSYVVDMIHLDVINFAIFNVADSYLTIGVLLLVICLWKEEDYGN"
     gene            complement(26321..27250)
                     /locus_tag="TV188_000902"
     CDS             complement(26321..27250)
                     /locus_tag="TV188_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEL1534276.1"
                     /translation="MNIQQLRYVVAIANNGTFREAASKLFVSQPSLSVSVKDLETELG
                     FQIFRRTTAGTVLTSQGLLFYEKALEVVKCFDSLEKEFSQSALEPNEFSIASQHYDFL
                     PALITAFSQKHAGHKVFRVFESTTMQILDEVAQGNSELGIIYLNAQNRQGLFQRMDKL
                     ALDYVELLSFTTHIYLSKNHPLAQRKALFLEDLQGLPAVRFTQEKEEYLYYSENFIDT
                     SKSPHIYTVSDRATLNGILERTAAFATGSGFLDQQSVNGIKVIPLRDHMEHKMIYVKR
                     RDKNLSAAALHFVTILQDYFEHRKEKQAIDNGT"
     gene            complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TV188_000903"
     CDS             complement(27657..27950)
                     /gene="rpmA"
                     /locus_tag="TV188_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEL1534277.1"
                     /translation="MIKLNLSNLQHFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVSG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(27972..28304)
                     /locus_tag="TV188_000904"
     CDS             complement(27972..28304)
                     /locus_tag="TV188_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEL1534278.1"
                     /translation="MIKVRLTKDAAGWTEMLITGHAGSGEYGFDVVCASVSVLAFNLV
                     NSVEQMTGLEPALEMVDGGGFLRVTKPEGFTEQQEQVWQILFESVVIGLENLAEHLSE
                     YVQKPVMN"
     gene            complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TV188_000905"
     CDS             complement(28317..28631)
                     /gene="rplU"
                     /locus_tag="TV188_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEL1534279.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAIYVEKIDAEAGAEITFNEVVLVG
                     GDKTVVGTPVVEGATVVGTVEKQGKQKKVVTFKYKPKKGSHRKQGHRQPYTKVVINAI
                     KA"
     misc_feature    complement(28665..28739)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(28861..30054)
                     /locus_tag="TV188_000906"
     CDS             complement(28861..30054)
                     /locus_tag="TV188_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEL1534280.1"
                     /translation="MLKDFQYKKTMLSVLTLIVVILVFGLAFDLLGMSKKGTQTKSKT
                     PQKTQTARVVANGDILIHDILYMSAKKADGSYDFNPYFEYVKDWISQADLAIGDYEGT
                     ISPDYPLAGYPLFNAPEAIAAALKHTGYDVVDLAHNHILDSRLEGALNTKRVFADMGI
                     DSIGIYEQDRSKENILIKKVNGIKIAILGYSYGYNGMEATLSQEEYDKHLSDLNEEKI
                     QKDILRAEKEADITIVMPQMGTEYALEPTAEQKTLYRKMIDWGADVVLGGHPHVVEPA
                     ETIVKDKEKKFIIYSMGNFISNQRLETVDDIWTERGVLMDLTFEKKGQKTKIKTVKAH
                     PTMVLAKPKGLYGSEGYELYSYRTMVLEDFIKGGRYYDKIDPETQEKAAIAYKEMNAL
                     VNLKW"
     gene            30319..30936
                     /locus_tag="TV188_000907"
     CDS             30319..30936
                     /locus_tag="TV188_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3862 domain-containing protein"
                     /protein_id="HEL1534281.1"
                     /translation="MKHNSFSRSLLLPLLICSLSACSSHTEKKDHTKDATAITDTRKA
                     EHQDIRANMEKVKLATASTDFKGGSSLEELITIFGQPSQHEEKAAGSVTLDSYTWQFD
                     HVTVNINLYENSSIVKTIANFAFIRDLTLSLKDYNSLKKGMTYDEVKQLLTEPDNYSQ
                     ANSSEKETIQAIWISGLKAQTQGANIALTFENNQLTEMSQVGLED"
     gene            complement(31234..32463)
                     /locus_tag="TV188_000908"
     CDS             complement(31234..32463)
                     /locus_tag="TV188_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1534282.1"
                     /translation="MRGLIKNVVFRTLTVSNFLSALGSYIYNIVFIIYATTLPYSHIA
                     VFIANIITIIPMVFTFWIGVKADKTKRKTRNLIVIGFIQSLLFTLVALLMTNQTFLVF
                     AFVGFLNVVSDILSDYKNGLRLPIMQKNIESEKLYEAYSFAQFIGYLSSIAGQALGVW
                     LLTTSGNNYAFVALINAISFLLSSVVLLKNRQKLRHDVVEASEAGVSLMKQFKVMYTR
                     MTETFKKIDHISFVMLLLSILTLNAIGGAINSIYHFYLMDHQLFHFHYGQSLVIVDAV
                     TIIGAMLGNLTPKDYFSRLSISKLVQTQGIAFLLVGVSNALQLPAIIGVLCLAFAAYI
                     MGKATPKLDALLMENLPSDMLAQSNNFLGLLFSLSLPVGVFIFSFLALYNMTLCWILF
                     MVLSLAALALSTSSTRG"
     gene            complement(32498..>32918)
                     /locus_tag="TV188_000909"
     CDS             complement(32498..>32918)
                     /locus_tag="TV188_000909"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HEL1534283.1"
                     /translation="ISYDNEIIEKGIDFILESLVEDSDGNRGVLISENSVSPYLSNGT
                     AGIVQLLIYVNSDKYIKDIKNLSESLLVEFAQFSGLWNGMLGIAMTLLQVFRLTNDTL
                     YLEKACELLISSKIMSEHHIKLQYEFRYAVSIFNQVK"
BASE COUNT         9933 a         7642 c         5865 g         9478 t
ORIGIN      
        1 aatcaaaaga agatagcatt tctgctatct cactgttagc cactacttac aggtaaaaat
       61 acaccttgtc tatttgtagt ttaactatcc atttaatcca tcaataagcc aaaccagacc
      121 gtttaatcat ctacccagcc ttacacatag tattttctca catcatttgt agaattgctt
      181 tctccttgca tgtcaccatc tcgtcttaaa cgttcgtaaa gggctgtttg atcttttcta
      241 actattttag aaaattattt tgctgttctg atgaggttaa tctcgttaga tcagtcatgc
      301 tggaggtagc taccgtatgg gagcgtcaaa ataagtcagc tgataatccc ctataatacg
      361 attgagcttt tcgccatagc tagtatctgt ggcatatgtg cctgttaaac tagcggtggc
      421 ctgctgataa cttgtatgaa tacctcggtg agtagggcga taaagcgggt cactcaaaac
      481 cctagcataa tcctcaaagc aggctgttaa gctgccatag gaccgaaaag aagcgtcaat
      541 tagataaagg ttgccttggc catcatcttc caaggtaggt aaaataactg attttccttt
      601 atagcttcct ttgataccaa aaaaattata atagggctct tgacttagct tagattgacc
      661 atttgctgac tccaaaatag cctgtgccat catgactgag gcatagagct tgtttcgctg
      721 cgcaactgcc tgagcggaat gactaatctt gctcacaaat agcatggttg agctattggc
      781 atgaggctta aggtgatcct tagctgacgc taaggtccaa aggctaagca acatgctgcc
      841 taaaacaata ccagcagcca gccaagagct agcttccctg tggcttcttc tagctttcct
      901 cctcttcaac agaaatatcc tcacttcctt gcttttaaac ctagtatagc aaaaattaaa
      961 agcaaaatgt agccagacca catgctcacc tcaaaaacag gccttatgac ttctaaaaag
     1021 acctagcagc cacaacaggc gcataaaaag tttttaacaa gaaaagaaga ctttgctgta
     1081 tttcaatcca cgctcctgca aagggagcga tacaaaaaat aaatggaata tctacaatca
     1141 aatgatttca atgtttagct atttcaagaa tatatcttat ttttgataga tgttactata
     1201 ggaaaaacgt tgatagtatc tactttaatt gatactataa ttcgaaaata actgtttcgc
     1261 acgtttggtg tggcttagtt tagcagggct attgggtcac tgcttagcta ttctagatca
     1321 gattgattct ctctaaatat tagcttttcg ccagtcatca ctactagcaa caaacaaaac
     1381 gcacgacatc atgtaaaaac aggctgatgt catgcgtctg atgttttatt aagactaggt
     1441 ctaattcaga agctttccct agtacttgtg gctttatagc cagtaactaa gcttttttac
     1501 gaagtgcgcc aaagagaata ccagaaacca ctgctccaat agcgacaaac aataggtata
     1561 agaaaggatt gcttgtcaaa gcgataacga agataccgcc atgtggtgcg attaatttga
     1621 cacctgctag accaacaaga gcacctgtta gggcagagcc agcgataaag cttgggatag
     1681 cgcgtgctgg gtctgctgca ccaaacggaa tggctccttc tgtaatgaag gaaagtccca
     1741 taataatgtt ggtcaagcca gattcacgct cttccttggt aaatttgtct ttaaataaga
     1801 gtgttgccac aaaaacagct agaggaggca ccataccacc tgccatgaca gcagccataa
     1861 caactgaccc accgcttgca acggttgcag caagtgttcc tgtaccaaag acataggctg
     1921 ccttattcac tggaccaccc atatcaacag ccatcatgcc gccaacaaga agtcccataa
     1981 gaactgcaga gctacctgac agactttcta agaagtggtt caatgctgta ttgatagctg
     2041 ccataggaat attgatcagc agcatcaaaa gacctgtcac aagaacacca agtaatgggt
     2101 aaagaaggat tgacttgacc ccttcaagcg aacgcggaag ccctgcaagc acttgacgaa
     2161 gagcaagaat tactccccct gcaaggaagc cacctacaag cgcaccaaga aatccagacg
     2221 gtactcccgc taatgatagg ctagcctcac cgccagcagc aaatggaacc tttccaaaag
     2281 caagaccgct agaagcaatg gcacctgcca caaagcctgc cacaagacct ggcttttcag
     2341 cgatagaata agcaatgtag cctgctagca ctggcaacat gaatgaaaag gccgcaccac
     2401 caatatgttt aaagatagct gctatttcat ggtaggatcc caaattagac agctgatcct
     2461 ttggtacccc aagcatgttg tcaagcaaga aggcaagagc aattaggatt ccaccaccaa
     2521 ttacaaatgg cagcatttgt gatacaccac tcatcaggtg cttgtagaag gctccgccta
     2581 ggcttgtctt ttgagctgct tttgcttgtt cagcagcgcc attcttggca tgataaacac
     2641 taccagcatt gtttaaaatc agtgaaatca attcctcgct tttcttaata ccatctgcta
     2701 caggacgagc aatcaattgc ttaccatcaa agcgatccat ctcaaccgcc ttatcagcag
     2761 cgataatcac tcccttggcc tgcttgatgt catcagctgt caggcgattg ccaacccctg
     2821 aagcaccgtt ggtttcaacc ttgatgccga cacccatctg tgcagcctgc tttttcaagg
     2881 cctcttctgc catataagta tgtgcaatac ctgtcgtaca agctgtcaca gcaacgataa
     2941 actcctgagc atttgtagga acaaaagcta cctctttctg atcagaagcc gcatcaaaga
     3001 cagcaatcac ttcgtctgga cttgttgcct ttcgcagttg atctgcaaag ccatccttta
     3061 ataggtattg ggataattcg gctaaggccg ctaagtgagt atcatttgcc ccttgaggtg
     3121 ctgcaatcat aaagaacaga tcagttggct gaccgtctaa ggatttgtaa tcaacgccct
     3181 tgttagattt tgcaaagagc actgctggct ggtcaacaac aacatttttt gaatgcggca
     3241 tagcaatgcc atcgccaaga cctgttgagg tttgctcctc gcgagctaag atactctttt
     3301 taaacacatc aaagtcatgt acaatcccat gctctactag ttctgtaatc atttcatcaa
     3361 ttgcagcctc ttttgaaaca gcctgcaaat caagaatcat gatgtctttt cttaataaat
     3421 cctgtatttt catcgaacct ctacctcaac ctcattatat gtttttttaa tatcatcaat
     3481 tgctgctaaa tcatctgaaa aagcagttgc tgttccgcag gccactcccc attttagagc
     3541 ctctagcgga ctatgacttt tgacaaaggc acctgtaaag cctgccacca tcgaatcacc
     3601 agctccaaca gaattcttca cctgcccttt aataggctta gcaaaataag ttgcttcctg
     3661 agtgaccagc aaggcaccat caccagccat cgaaacgata acatgctgcg ctcccatgtc
     3721 aaggacctta cgagcatatg tttcaacgtc atctagccca tttaagctga cgttaaaaat
     3781 agcttctagc tcatggttat taggctttac gagcaatggg tgatacgcca atgcatctag
     3841 caaggtctgt ccttcaaaat cacagaccac ctgtgcccca gcttgtctga ccaatgggat
     3901 caagtcctta tagacatcat tgcctagact tgaaggcgct gagcctgcaa aaacaacaat
     3961 gtcctctgct gacacatttg ccaatatagc ctttaaatga tccaattgct gctttgaaat
     4021 cactggtcca aggccattaa tctctgtctc ctctgctgat ttgatcttaa cattgatccg
     4081 cgtatcctga tcaaccgtta caaagtcagt attgatgctc tcagcagcta gactttcctt
     4141 aataaaacgc ccagtgaagc cgcctaaaaa gccagtcgct gtattatcaa tgcctaatcg
     4201 ctgtagaatg cgactaacat taatcccctt tcctcctgca aatgtatcgt cactgaccat
     4261 gcggttaacc gctccaatat ctaattggtc tattctgaca ataaagtcta tagaaggatt
     4321 taaggttact gtgtaaatca tagtgcaatt accttcgctt tttccttgat tttcttcagc
     4381 attactgtcg aagatttctc tgtaatgatt tcaaccctat caattggagc aaccttgaca
     4441 aaggaaacat gaccaagctt tgttgcatca gctaatacat aggtgatttt agcattggca
     4501 atgacagctt ttttaataac agcctcctcc atatccggag tggttaaaaa tgcctcatcg
     4561 ataccattga taccaagaaa agccttatca aaattcattt gcctaatttg ctccaaggca
     4621 acatgaccga tgcttgcgtc tgttgtctgc ttgacatagc caccaataat aatggtcttg
     4681 atcgccatat caaccagtct agtcgcatga tgaatagaat tagtcactac tgttactttt
     4741 tttaattgca aaaaaggaag gagaaattcg gttgttgtcc cagcatcaat aaagatgaca
     4801 tcattatcaa aaaccagctc tgctgccttt tgagcgatga tttcttttat ttgactgttt
     4861 ttgacagatt tttcctgatt agataattcc tcttgtaagg aatgaaaaag ctcggcacct
     4921 ccatgcactc gatgaagctt gccctcacgc tccagctcat ctaaatctct acgaacagtt
     4981 gattctgacg agcttaacag ctgcattaaa tcctctagcg caacgtaatt ctcagctgtg
     5041 atttttgcca taatgagctg ttttcgtttt gattttaaga taaaaccacc cctttgtctg
     5101 aaatcgttta cagctctatt atactacact ttattccaaa gtcaagcact atcttttaaa
     5161 aacattcaaa ttcaatctta gacctctatt gccttaacaa taactgccaa ttgatcagtc
     5221 attgtccccg tcaatacctg tagactaatg attaacgact tttttattaa ctagagccca
     5281 aaaagcgctc acctgttgca aaagtctgaa acacaatagt ctcttacaaa tcaaaaagca
     5341 acggatttac tgtcgttgct tcataatgag agtctaggac aaagtctttt cagccaacaa
     5401 gacaaaacga gagagtcacc tattgtgagc ctctcgtttt attgtactga gaaattgttt
     5461 tatcccagac tccttatgtc taaacctatt tgatcttcaa aatattctct ttggcatgga
     5521 ctagctgtgt aatcaagcgg caataagggg tatcgatacc aagcttttca cccttggtat
     5581 ttaccgcacc gttgataaag tcaatttcag tcaagcggtg attttgaaca agatcctgat
     5641 gcattgatgg gtagtgatga gcagccttca ctgaggtttc catcacatag gctgtgattt
     5701 cctcttcatt aagctccacc ccctcagcac gaccaacaat aacaaactca tgaatgattt
     5761 ctttaaccat gtttaaacca tcttcgctgg caaataactc accaatcgtg caatcaagta
     5821 gggcacaggt tgagttcatt gtaccattga cacaggcttt tctccaaata tttggaacaa
     5881 cattatcatc ataagttgca ttcaattgag cgtcatttag caagtcagca atctgatgtc
     5941 ctgcctcttg gtttgctgga tccatgcttt gtagattaag cgcaccaact ccttgtaagt
     6001 gtacctgacc aggtccctca agacccgctg tccaaacggt aacacccatt aaaatattat
     6061 gctctggaat atagtgacga atcacatctt cgtgtccaag accatttaat aggcaaagta
     6121 ccttggtttc agggccaata atacctttaa tatcagtcag catttgtggc agctgcatgg
     6181 ctttggtaaa caaaatgata aggtcagctt ccttagtagc ctctgtcggc ttcatgatag
     6241 gaagctttac ggtttcctct acatcgcctg aaatcttcaa gccattctct ttgatcgctt
     6301 gaagatgtgc ttcccaatta tccagtaaaa taacgtcatt gtttgttttt gaaatttggt
     6361 aaccaaatcg acagcccata gctcctgagc ctgcaatata aactaacatg ctttttcctc
     6421 ttatccttca aatacaaaaa tatcttcttt ataaagcttt aaaatatcct tacaaagctt
     6481 atgtgccaca aaagcaactc caaatggaat gaccaaccaa gcaatgataa tgatcacaat
     6541 attgctgcca ccggcaagtg aagcaatagg accaactgca ccaacaagac caaagccaga
     6601 tgaggctggt gttccaatca gattaaacat tggaacggtt aaagagctaa caatagctgt
     6661 catcatcatt ggaatagcca taactgggta ttttaagaag tttggcatca tcattttcat
     6721 agcgccaagg gcaatggcaa ttggaacacc tgatttgtta acctttaacg ttgcccacac
     6781 aagaacagcg gttgttgaag caatacccat tgaggccgca ccagctgcca taccatttaa
     6841 gccgatagct aaaccaatcg caaccgttga gatcggactc acaatcaaaa gagcaaaggc
     6901 aatggcaatc aaaatagaca tcagaattgg ctgaagcgtt gtaaatgaat taatgccttg
     6961 gccaatcagg gtcgtcacat aagaaacgta aggaagcagc ttccagccaa tgtaacccac
     7021 acctgttcca ataataattg gcaacaaaat aatggttaga gacccaaatt tatcaccaaa
     7081 ccacttcact gctaaaacgg caagcgcagc tgtgatcatc atattaatca gatcaccaat
     7141 gccctttagc tggaaggtcc cagtggcaac acctttttgg ataacctctg tataagccca
     7201 agctccagaa ccgatataag ctgccccgcc gacagccagc tgctgcattg ggttaaattt
     7261 gaactgctgt ccaatcaaaa aaccagccat aactggcgta aagaattgga aaacctggac
     7321 gatatgtaaa aattcagctg ctacagtatt tggcaaaagc ggctttaaaa acgtcgctaa
     7381 aatagcattc ggaataagtg caactacaat cgcaattgct gtaccagcta agaccttatt
     7441 cataaacgag ctaaaggtct ctttatttgt tgttgtcatt tcatgacctc tcttaatatt
     7501 atagtgtgaa aaacatcacg aaagtattct aacataaaaa gagcattttg tcacagctat
     7561 tttaattttt atcaatacgt acagaatatt caattaaatg tcatataata ttaatcaatc
     7621 aaggctgttg aatgaacagg tctattatct ctatcaggat aaatatactt aatcgcttgg
     7681 ttgacagcaa tcggtgcctc accaaagcca gtggcaatca aatcaaccct gccttcataa
     7741 gctgctgcgt caccgatcgc aaaaatccct tcctgacttg tttgaaagag gggagagaca
     7801 agaagacttg agcgcttata atctagattc caatgcttta ggtttttatt agatgtagaa
     7861 aagccaaagc taacaatcag gctgtctagc tcaagcgtta tctcctcttc tgactttacc
     7921 ttttgaatag tcattttgtt gacaaagcca ttttctcctt cgagggcaag gggaacaaag
     7981 ggggtaaggg tagtaacatg agagtttttt aacaattcta cgctatgctc atgagcccta
     8041 aaggcgtctc gccggtgcac aagggtaaca ctcttagcga ggccatctaa ggctaaagcc
     8101 cagtccacag cagaatctcc accaccgcag atcacaaccc tcttaccagc aaactgattc
     8161 aagctgtgaa cattataaaa gagattatga tcagcaaata actgctcatt gtctaagccc
     8221 aaggttctag gcgcaaaggc tccattgcca caagcaacaa taatggcctt agaataatgt
     8281 ctggccttgc ttgtttgaat aacaaagttc ccatcagcct tctcaaaaga caggacctct
     8341 tctttcaggc atactgctat gcgatcgtca aatctgctta gctgctcaat aagcttttgt
     8401 gttagttccg ctccagtcag ggccggataa gctggaatat catagataac cttttcagga
     8461 taaagaacag ccggctgtcc tcctagctct gacaggcttt caataatctt aaccgtcatg
     8521 ccgcgcaggc ctgcataaaa ggctgcaaat aagcctaccg gacctccacc aatgatggta
     8581 atgtcatata ttttttcttg cactagttct ctccttcact tagccccgat ttgattttat
     8641 caaaaatcct tttttcctca tcagaaaaat cataagtctc taataaatct ggtcttctca
     8701 aataggtctt ctttaggctt tgctccatac gccagagacg aatatgctca tgatggccac
     8761 tcattaggac atcaggcacc ttcatgccac gataatcata tggccttgta tactgtgggt
     8821 actccaagag cccagatgag aaggaatcct cttgatgact ggcttgcttt ccaagcacat
     8881 taggaatcag tctcactgtt gcatcaatca ttgtcatagc agccagctca ccaccagtta
     8941 agacaaaatc tcccagagat atttcatcgg taacaagtgt cttaatgcgt tcgtcatagc
     9001 cttcgtaatg cccacaaata aaaattaact cttcctcaag agctaattct tcagcataag
     9061 actgatgaaa gggttttcca gcaggatcca gtaaaatcac tcgaggcttt gtagcctgaa
     9121 tgctatccat ggtatcaaaa ataggctgcg ctctcagcag catgccctgc ccaccaccat
     9181 atggctcatc atcaacatgc ctagctttct ccgcatggtc acgaaaattg tggtaatgaa
     9241 tatctaaaag ccccttttcc ttagcctttc caacaatgga gtgctccaaa ggagcaaaca
     9301 tttccgggaa aagggttaaa atatcaatct tcatcatcta agccttccat aatttcaacg
     9361 tctacccgat gcttttcgat atcaacacaa agaacaaccg atgggatata aggaagcaac
     9421 aggtcacgct tgctttgccg tttgaccacc caaacatcat ttgcaccagg ctgtaaaatt
     9481 tccttaatct ctcctactag ctggtccttt tcatacacct ccagaccaat aatctggtga
     9541 tagtaaaatt ctccctcagc tagcttaccc tgattctctt tagcaatctt aagactgtag
     9601 cccttaaatt gctcaatagc attgatgtga tacattccct taaacttgat aatgtcaaac
     9661 tgcttatgct tgcgatgact cgcaatctca acctcctgca caaaacgatc cttgtcgtca
     9721 aacagggcta gtctagcacc tttttgaaat cgttcctcag taaagtcact cacagacagc
     9781 acgcgcattt ctccttgcaa gccttgagta ttgacaatct tcccaacgct aaaatattcc
     9841 atccttactc ctaatcatct tagactctat agcttgatag acctctattt tttcatgaca
     9901 acacgacatg agtatcatca tcctaagcac tctagcctat cgttaaagct ccccttattg
     9961 taacatgttc tgccttattt tgcacttctc tttcaaaaaa ttaatctccc agttatagca
    10021 gctaagccta gcaagcaaag cccttgatgc taaagaatcc tgatccccct ataattaaca
    10081 aatcatcatg acttgccttg cccaagctca gtcaagtgaa tgaaaaatct gctaaacaat
    10141 agccttgcgc ctcgctgaca agcatcaaaa aaacactcct gctggcaatc tgaactgccc
    10201 cccaattgtt agattttatg tccaactttt gggggtcagt acaatctagt aaactagaat
    10261 caggagtgtt tcattatagc ccaacaagca aaaggaatac ttggtaaaag caaagctgac
    10321 ttgcattgag aagattaaaa ccattcaatc tgtcacaata attatggaaa cattgggaat
    10381 ttaaaaacaa gtatcagctg ctatcaacct gtggggaaat agtctaccta tgcctatcgg
    10441 gccatccatc ataggtcctc tcaagaaatg atgagagcct catcaaccag ctatcatcgc
    10501 cttaaaggag aatgacgaat gttatcgtag gtgtcccaag aaatactaca aaagaaactc
    10561 attttgatct taatgctcta aagggcttga ccttacgtca actgataaag ctctacttca
    10621 tagcatcgtt ttgctttgca gcttttctat acctcatgtc taataaaaga cataagcttg
    10681 ccgataagaa cattacccca acatagaaga atagattggt ctcatcgcca gtctttagta
    10741 agatggtatt ttgatgcttc atcggtttgg tagctgttga aacatgcgga cacttggttt
    10801 catttgtcgt cgatggtatt gtcggacgac ttggcttagt gttattaggc ttatgattgc
    10861 cttcactact gcttaccttt ttcttccact gtgcaaacaa ttcattagga aacggcaggt
    10921 cattatctac cctaatgtca tcacctacct tttttaacct cctgctcgat ctcttgttgc
    10981 atacaaaatg ttatacagat acttctgtca gatagagttc ttgcttttgt ctcttgactt
    11041 ggtgattcaa aacacaaaaa aagcctgcta gatagaacta gcaaggcttt aagattagtc
    11101 ttgttcaaaa tagaacttat ttttcatcaa tgactaatcg aacctttttt cctaaagttg
    11161 gcaccgaata gacaatcgat cttatcgctg tgatggtacg acctttcttt ccgataacac
    11221 gaccgatgtc ttgagcatcc aagtcaagat ggtactctaa aaaatccgga gtatcttcaa
    11281 ttttaatagt aagcttatct ggttgtgaaa tcaagggctt cacaatagcg ataatgagat
    11341 tttcaatggt atccataggc ttttattact tagaaaattt ttgatcgtgg aatttagcca
    11401 taaccccagc tttagataga aggctacgaa ctgtatcaga aggttgtgca ccttttccta
    11461 gccaatcaag aacacgatct tctttaagag ttacttgatt ttcagctaca agtgggttgt
    11521 aggttccaac tgtttcgatg aaacgaccat cacgtggtgc acgtgaatct gcaacgttga
    11581 tacggtagaa aggttttttc ttagaaccca tacgagttaa acggattttt actgccattt
    11641 taatatgtct cttttcttta aatgataata gtcaagaaat gtagtcctgc tcatttctca
    11701 cctaactagt atactttact tttgattatg tgtcaagttt ttttcttgac acttttttat
    11761 gatcataata ctactcaaca tcttcaatca gctaagctgc ttagatgaca tcaaacagca
    11821 ggcagctgct cttataagag catacaactc caaactaacc tactctagtg atccttagcc
    11881 gtcaataatg ggatcaggca agcataactc cccgtcaaag gagcggtttg tttcacagca
    11941 aaaaggcgaa ataaactgac aatcacatca aaaaggacga gcccctaaac atgcaggagc
    12001 tcgtcctttt accaatatga cttagtctct ccttgctttt aaggctaggg tattagctaa
    12061 gcgttacact aataatgcat caaaatatgc ttaagaaact ctccaccata aatccaaaaa
    12121 taactgaagg tcaaaattga aatgggtcta caaattagga taatcagtaa aaagcgcttg
    12181 taggtcatct gactcaatcc agtaatcata ataagagcat cggcaggggc taagggggaa
    12241 atcatattga gaataaagaa acgctcaaat aatttcgttg atagcttctt ttcataaaac
    12301 tgtagctgct ccatacttaa aaacagtaag ataaagggct ttccgtatct cctcaccaac
    12361 tgaaacaaaa tagaagatcc aatgcagata ccaaacacat ttaacataaa gcctaatata
    12421 ggaccaaagg ctagaaagcc aacgactgtt gtcacaccac caggaatgat aggaacaact
    12481 acctgcacaa tttgcaagat aaaaaagcaa atggcaccga taaggagatg atccttgatt
    12541 aaatgggcta aagcctttgg attattaata atatctagct gcctaataag gtagacaaca
    12601 agcatgacgg agaacagaat tgataggcca ccaagaatct taaacagctt ctttaacaac
    12661 gaatgtgaaa caccaaagct actcatagcg caaagcctct atcggatcaa gcttgcttgc
    12721 tttgtttgct ggcagcaatc caaaaataat accaattgat gccgaaaaga taatagctac
    12781 agccgcaaca tctaaggaaa cagctgctcc ctttaattgc atcgcatttc ctagcacacc
    12841 tacacacatc tgtgctagca gcagccctaa aagaccgcca attaacgtca acaccactga
    12901 ttcaatcaaa aattggctaa gtatcttcaa gcgcgttgct cccaaggctt ttcgcaagcc
    12961 aatttcacgt gtacgctctg ttacagatac cagcatgatg ttcataacac caataccacc
    13021 cacaagaagg gaaattcctg caatggaccc aacaactgtg gtcatgatac taaattgtgc
    13081 gttaatgtca ttgataattt ggctattgtc aggaacagcg tactcgccct ccttaacatg
    13141 agacagtgtg gtcagcatag cagctgcttg atttcctaat tcaaggcttc gcttaacgtc
    13201 gccaatataa agataaacag agccaatttc cttgacatga aattctgaag ccacctgggt
    13261 attggccata atggctcctc cagaaatccc accagcaaac gaaacaacct cctgatcagt
    13321 cttgtaaaca cctactacaa ggtagtcctt actatctaga ctaaccacct tatttagagc
    13381 ttgttcataa ttgcctttgc caaataattc gtcagccaag acagtatcta ataggataat
    13441 gcgagaaaaa tttttataat ccttgctatt tagcgtccta cctgcaacaa tatcatattt
    13501 tttgacttta aaataatcct gactaacccc agtgatggcc acattgtcca tcttcttttt
    13561 ctcaaaggaa atggtagagg ttgaattatt ggtatagtaa taagaatcta ccccatcaat
    13621 tgctttgaca atctgctcta gccattcagg cttgacctct tgctcatttt catgcgctgc
    13681 aaaggccgcg taagggttgt cctcatctcc ttttgccttg aaataaagct gaacctcttt
    13741 ttggtcattt gaaaaggaat ccgtaaccct ctttgtcatg gcagcaccaa gccccatgat
    13801 aatcacaaca gcagctacac cgataataat tcccagcatg gtaagaatcg aacgcagctt
    13861 gtgcccccag attgaactaa gagcaaattt ccaattttcc atcacttttc ctcctagtca
    13921 atcctgacac tttctgttgt atcagctgtg atttcaccat cacgaataac aatttttcga
    13981 gtggcaaagt ccgcaatctc tggctcatga gtaaccataa taatagtttt gccttcctta
    14041 ttcagctccg tcaaaagcct cataatctgc tcaccagtct ttgtatctag ggcaccagtc
    14101 ggctcatcag ctaagataat agacgggtta ttaaccaagg ctcttgcaat ggcaaccctt
    14161 tgcttttgac cacctgataa ctctgatggc aaatgcttca ttcgcatacc aagctcaacc
    14221 ttttccaaaa attgcttagc caattcacga cgctttgata ctccaactcc agcataaatc
    14281 aagggaagct caacattttg cagggcattt agctttgcta gtaaaaagaa ctgctgaaag
    14341 acaaagccaa tctcttcgtt tctcacctga gcaagctttc gatcatttag gatctcaacc
    14401 tgtgtgccat tgagacgata atcacctgag gttggtctat ctaataagcc gatgatattc
    14461 atcagggttg atttccctga gccagaaggc cccataatag cgacaaattc accctcatat
    14521 acagtcaaat ccacgccttt taggacctgt agctcctgat caccattttg atagctttta
    14581 acaatgcttt ttaattgtat taattctttt ttctcatctg gcactactta atcacctcgg
    14641 attctttact gcttttttta gaatcttttg atgcctttgt gtctgcggaa ataacgtctt
    14701 ctagcttttc accctctttg atgttcttat cagggttagc aatgacaata tctcccacct
    14761 ttagacctgc acttacttct tgtctttcag catcagcatt gcctagggtt acttcaacct
    14821 ttttagcctt tgcagttgag tcatcataga cccagacaaa atgcttcttg cctttgttaa
    14881 cgatagcagt aactggtact aaggcatgct ttgcttcgtt gataacctca acagacaccg
    14941 taaagccttg ctttagctgg ttaagcggac tcgtgatatc aattttgtag tcataggtcg
    15001 caccagttga gcttgatgag cctgagcctc ctgcagttga accacctgca ttggcatcgg
    15061 ttgggtagtt tgacacataa gaaatctttc cggtccactc ttgatcagca tagacctttg
    15121 atttaatctt cacagcttgt ccaaccttaa tattggctaa atcatactct gttagggtcc
    15181 ctttgacctg taacttgcct tcggttgcga catgaaccaa ggtttgactg ttttttgaag
    15241 acgggtcaat atcattatta acctctacaa ctgtccctga aacaccactg acaactactg
    15301 tttcatttaa ggcctgctgt gctttattga cctctgcttg agcatcagca taggaatcat
    15361 ttaaatcctg caattgctga gcatagctag cattttgctg ggctgagggc tgaatggttg
    15421 tggtggtttc ttgccctgtc tcctcgtcct tgcttgtctc agtagttgct gctggaacac
    15481 catacgtttt taaatgatta atctgacgcc caattttatt gagattgcga acagcggtgt
    15541 cataagctgc ctgtggtaca gttgtattgt actgtactaa ctgctggcct tgtgtgacct
    15601 gatctcctac cttaaccgta acggtagcgt ctgagccttt gctagcatca aaataaacat
    15661 attcttctga aagagcttta acagtaccag agagtaaggt tgaagaggct attgtccctt
    15721 ctgttacatt taccgcagaa taaggtagct tgatattttg atcagagata gtatcttgct
    15781 gttgcttcca caatactcca ccgataacga ctacagttag tgcaactgca cctgcgataa
    15841 tgcctttggt tttcgttgat aactttatct ttcctctttt agacatttct gtcctcccct
    15901 tttgtactat ttttgtaaga caagtatatg atgtttttaa aaacttgtca agaatttctt
    15961 ggataagctt aataaagcag cctcttcatc atgtagatga caactctatt ataatggttt
    16021 ttcaagctgt actagcttac acttttgtaa tattaaaaag aggcaaagac aaaaagagtt
    16081 gtcctttaac tttattacac agtctcattc attaaaaagc gaacaagcct agttttcaaa
    16141 atctcagaaa actagacttg ttcgtttgtt tagacttttc tctcagtctc ttcatcaggt
    16201 ttaaatagct tctatactaa aggtacggct ttcaagaact ctcagcattg ctactgctgt
    16261 atccaatgct gtaaacagag gaactccttg ttcgattgct gagcttctga tcatctgccc
    16321 gtccttatca gtcactcgtt ttgttcctac ggtattaata atagcttgaa tctgcccttt
    16381 tctcagtaag gctgggatat catgagcatt gtcgccaatt tttccaacta gctgtgaatc
    16441 tagcccttgg tcagcaaaga aagcagctgt gccttcggtt gccatgatct ggtagccaat
    16501 agcactaaag cgtctagcta agatcagagc ctccgactta tggtcatcag cgatggtaaa
    16561 aactattgtt ccatattccg gcatgtgcag atagctagct tcaaaggctt tgtaaagggc
    16621 tttttcaagt gttaaatcag agcccatgac ttcaccagtt gatttcatct caggccctaa
    16681 aaggctatcc accttagcga gctttgcaaa tgaaaaaacc ggtgccttga tatgaacaag
    16741 cgagctttca ggataaaggc catcttgata acctaagtct tttaaggtct gacccagaat
    16801 aagcttcgta gcgacttgtg ccattggaat attggttact tttgataaaa atggcactgt
    16861 ccgactggca cgaggattga cctcaatgac atagacctgc tcattttgga tcacaaattg
    16921 gatattcatc atgccaatac agtttagccc tatagcaaga cgcttagtgt aatcaacaat
    16981 cttgtcttga acctgtttag ataggtgctg cggcgggtac acagccattg aatctcctga
    17041 atgcactcct gctctttcga tatgctccat gatccctggg attaagactg attgaccgtc
    17101 agagattgca tctacctcgc attccttacc aaggatataa gaatctatta aaacaggatg
    17161 ctcaggacta gccttgacag ctgttttcat gtaggagcgt aaatcgtttt cattttcaac
    17221 aatttccatt gctcggccac caagaacata agagggtctg accaataccg gaaagccaat
    17281 ggcacgcgct gcctctaagg cctctgcctc attggtggct gttttcccag gaggctgagg
    17341 gatccccagc tccttcaagg ctttttcaaa aagctcccta tcctcagcac aatctaagtc
    17401 ctctagctgt gtgcctaaaa taggaactcc ggccttggtt aactgctctg ctagattaat
    17461 agcagtttgt ccaccaaact gtaggattac tccctttggc tgctctaatt caataacgtt
    17521 catgacctct tcaaaggtta agggttcaaa ataaagcttg tctgatatcg aaaaatctgt
    17581 tgacactgtt tcaggatttg aattcatgat aatggcttca tagcccgcag cctgaatagc
    17641 cttgacagaa tgtacggttg cataatcaaa ctcaactccc tgaccgatgc ggataggacc
    17701 agagccaagg acgataacag attctttctc ggatttgatt gattcgtttt cccactcata
    17761 ggtcgagtaa aaataaggcg tttgtgagtc aaattcagct gcacaggtat caaccatctt
    17821 ataaactggc aagacacgat aggctcgcct taaccgtcta atacttgcag catcagtttg
    17881 ccaaagctct gcaatttttt ggtctgaaaa accatatcgc ttggcttcta tcagcaaatc
    17941 gatatcaact ggctttttaa taaggtcttg ctccagttct acgatatgac gtaatttatc
    18001 caaaaagaat aaatcaatct tggttaagcc agctagctct tcaatactat agccacgacg
    18061 aagggcctca gaaagataga atagacgatc gtcctgtgct cttacaatgt gagcaaccag
    18121 ctcatgatca ctgatagtat ctagaccctt cagttcgtta tggtgtactc caatttccaa
    18181 cgagcgacaa gcctttaaga gacattcctc aatacggcgt ccaatagcca taacctcacc
    18241 agttgctttc atctgggttc ctagacgacg ctccccccgc tcaaacttgt caaatggaaa
    18301 gcgtggcagc ttggcaacca cataatcaag agctggttca aacatggcat aggtggttcc
    18361 tgtgaccgga ttaagcatgt catcaagcct taagccaact gcaattttag cagctatttt
    18421 agcgattgga taaccagttg cctttgaagc cagtgctgat gagcgagata cccgcggatt
    18481 aacctcaatc acataatagc tgaagctatt gggatcaagt gccagctgaa cattacagcc
    18541 tccttcaatc ttaagggcac gaataattct caagctagca tcacgaagca gctgattctc
    18601 aacatctgat agggtttgtg tcggggcaaa aacgattgaa tctccagtat gtatccctac
    18661 tgggtcaaaa ttttccatac tgcaaacaac cagcgcgtta tcagcagcat cacgcatgac
    18721 ctcatattca atctctttaa agccggcaat ggagcgttca atcagacact gggtgacagg
    18781 agatagcttc aggccattct ccacaatatc tcgcaagacc tcttcattgg agcaaatacc
    18841 acctccagtg cctcccagag taaaggcggg gcggacaata acagggtagc caatggcatt
    18901 tgcaaagccg atagccgcct ctactgtcgt cacaatctct gattctggaa taggctctcc
    18961 caactctttc attaattgct taaataaatc acgatcctct gcctgatcaa tagcagataa
    19021 ggttgttcca agcagctcca ctcctaattc ttgtaaaata ccagccttag acagttccat
    19081 cgccatgtta agaccggtct gcccacctaa ggtcggcagc aaggcgtctg gtctttcctt
    19141 tcttaagata cgactaacaa atgccaacgt caggggctcg atataaacct tatctgcaac
    19201 ctctttgtct gtcataattg tcgcagggtt agaattaacc agaacaacct gatagccctc
    19261 ttcctttaag gctaaacaag cctgtgttcc tgcgtaatca aattcagctg cctgcccaat
    19321 aacaatagga ccagacccta tcaccatgat ttttttaata tctgtacgtt ttgccataat
    19381 atctggtaca aaaggcctta acaatccgaa taaaataatg caagcaccta acattaaagc
    19441 atcacaatct attttttact aggatttgta cctgtactca gctgcagcaa gccctttgta
    19501 cctactcctt tcattatttg ccgtctcaca gggcggcatt aaataaaaca cttaacagtc
    19561 tgtcacatga gacgatgagt acaagatcaa gtaaccctta gctcagcaag tatagatgac
    19621 ttaattgata tagtcttttt acttctaaag agggcgatct tgccagcaaa tactagtcat
    19681 aacccgcggc agagcgatca tttcccacta gtctatctgc tgcctgactc aagctgtttc
    19741 atgacagctg atcaagcctt tggtgcttgc tttttgatct gctagcacac ttgattaaca
    19801 tttgccttgc tgctctagct gccaggcgtc aatcatatct aaaaattcat caaatagata
    19861 gctagcgtca tgagggcctg gtgcagcgtc tgggtgaaac tgcacagaaa aggcgggaac
    19921 atgtcgatgt ctcacccctt caacagtttt gtcattaatc tcctcgtgcg taaccatcaa
    19981 gcagtctggc aagctgtcgc gctcaacagc ataaccatga ttttgactag taaaatcaat
    20041 acgtccggtc gctatttctc tgacagcatg attaaagcca cgatgtccaa aaggcatttt
    20101 aaaggtctta gcgccattag ctaagctaag cagctgatgg cccatacaaa tgccaaaaat
    20161 tggaattttt ccttgaacac cacgaatcat ctccaaggcc tccggcaaat cctctggatt
    20221 acctggacca tttgatagca ttagaccatc tgggttgagc tgtagaatct cttctgctgt
    20281 gatatcaaag gggactattg tcatctgaca ttgccttttg gataattctc ttaaaatgga
    20341 atgcttcaag ccaaagtcca ccaaaacaat atttttccca acacccggag cgggataggc
    20401 agtcttagtt gacacctgct caataccatt agtcggaagc acagttgcac gcagctgatc
    20461 ctttaggtgt tcaagcgtat caccatcatc tgccattgtt gccttcatcg taccatgctg
    20521 acgaatgatt ttggtcaacg ctctggtatc aattcctgaa atgcctggaa tccccttatg
    20581 ctttaaaaac tcgtccaagg tcatttgctg acgccaattg ctagctatcc tgcttacttc
    20641 agagacaatg acccctttgc aagttggggc aatggactca taatcatcac gattaatacc
    20701 ataattacca acaaggggat aggtaaatac taagagctgc ccgttatagg actggtctgt
    20761 gattgactcc tggtagcctg tcattcctgt attaaagaca atctcgccag tgacatcaat
    20821 atctgcacca aagggctttc cttcaaaaat ggtgccatcc tctaagataa gtaaccgttt
    20881 tgccatttta accccctcta acatgccttt agaccttatc gtttctgcca ttaaggatcg
    20941 cttcgataat ggccatacgg acaaatacac cattagccat ttgagctact attcttgcct
    21001 ttggagcctc tactaaatgg tcagcaatct caacatcgcg attaaccggt gccgggtgca
    21061 taataatcgc agagtccttt aaccgcctgt agcgctcctc agttagacca aactgtctat
    21121 gataatcttc cttggaaaag ctttgactac catcatggcg ctcatgctgc accctaagca
    21181 gcatcaacac atctaattga tcaataatgt gatcaatcgc catgtacctt ccatagctgt
    21241 caaattcaga cgagtaccat tgctcaggac catagaaata aagctctgct ccaagccgct
    21301 ttagaatctg catgtttgat ttagccacac gagaatgtgt caaatcccct gcaatagcaa
    21361 tcttcaggcc atcaaaatga ccaaattctt cataaatagt tagcaaatca agcaagcatt
    21421 gactagggtg ctgacctgat ccatcacctc cattaacgat agaggcagta atcgttggac
    21481 tgtcaataag ctgctgatag taatcatctt ctgggtgacg aatcacgcag atttctgttc
    21541 ctagagcact catggtaaga acagtatcat ataaggtttc ccctttattg acagcacttg
    21601 tatcagcgtt aaaatcaagg actctaagac caagcttgtt ctcagcaacc tcaaaggatt
    21661 tatgggttct tgttgaattt tcaaagaata aattagctgc aaagtgccta ctgttatctt
    21721 taatagctac cttacctgcc ttgtattcag agccacgact aataagtcct aaaacctctt
    21781 catttgttaa atgctccatt gacaccaaat gcttaagcgc aacacgatta tttacaactg
    21841 acatgattta tcccctttta ccaataatga aatgatgata acaattgaca acagctacac
    21901 actagttttc tggaagaagc tgatacaata taatgccaag aagcgttgaa aaagcaacac
    21961 ccgaaatctg aaggccattg atttgaagca tgaggcctcc aataccagaa accagaataa
    22021 cactagcaat caataggttt ttcttgttgt ccatatcaac cttagcttca atcaggattt
    22081 tcaagccact agaggctata accccaaaca gagcaatcga aatccctcca atcactggag
    22141 taggaataga ctgaataagt gctgatacct taccaacaaa gcttaacaaa ccagcaatca
    22201 cagcggcacc tgcaataaca tagactgaga agattttatt gagggccatc acaccaatat
    22261 tttcaccata agatgttacc ggaggcgctc ctaaaaatcc agcaatcacc tgtgcaaggc
    22321 catcacccgt caaggttttt tccaagccag gatccttgaa ataatctctt ttagtcaggc
    22381 tattaagcac catgatatga ccgaaatgct ctgtcatggt gacaaaggca atcggggcca
    22441 tcgttaaaat agcactagga tacaaggtaa tgtcataggt taaaaagggg atagccacag
    22501 ctggaacact gagccattgg gccttagcaa cctgtgtaaa gtcaacaata gactgacccg
    22561 tcaccatacc aacaaggatc gcaaacaaat agccaaccaa taagcccaac aaaataggaa
    22621 tgatggcgac aatcccttta ccataaatgt taaagaaaat aatcgctaat aaggtgacaa
    22681 gaccaatcaa aaggtataac aggttatact ttccatcctt tagcatgaca tcactaactg
    22741 ctgttgaggc caagctaaga ccgatcacca taacaatggg accaaccaca actggaggta
    22801 agatcttatc gatccattca ttgccaatcg ccttcaccac cagtgctaca accagataaa
    22861 ccaggccacc tgtaatcgct ccctgtgcaa ctgcaccaat accatctgtt ttcattagca
    22921 tttgcatggc tgcaatataa gcaaagcttg agcccatata agcgggaatt ttaaatgttg
    22981 ttactgacaa atgcgccaga gtcccaagtc cacttgataa gagggcaact gacggatcaa
    23041 tcccaaccaa aattggaacc aaaacagttg ctccaaacat agcaaataaa tgctggaagg
    23101 acaagccaag caaaatccct gcctttggca cttcttctac atcataaatg acatctttca
    23161 cacaatcacc tctttcttat cccggatcaa caatactaat acgatcttga ccgtcaacct
    23221 caaccacctc aacgacaatc tcttctgtct tgcttgtggg aatattcttt ccaacataat
    23281 cggcccgaat tggtaattca cgatggcctc gatccaccaa aacagctagg ctaacacgtc
    23341 caggacgccc taagctaacc aaattgtcga tagctgcccg aatcgttctg ccggtataaa
    23401 gcacgtcatc tactaagata atatccttgc cggtaatatc taccggcatg ctggtggtgt
    23461 cctcttccac tctcatatca tctctaaagg gcttggtatc tagctctcca actgccaagt
    23521 gcaggctttc tagctgctct aatctttctt gaatacgacg agcaaggtaa acacctcttg
    23581 ttttaatccc tacaagcacc acattgtcta gttgcttgtt gcgctcaata atctcgtacg
    23641 taatccgcgt gatcgcacgc ttcatggtta gctcatcaac aattaccttt gatttcattc
    23701 aaagcctcct caaaaaattc aactaaaaaa atctccctgt taacaaggag attcagcaaa
    23761 acaggcacac agctagacat aactgtgcac ttttttattc agaacatgct ccttgccagc
    23821 ctcacaggac tgttttaaag gaatatttta ttttcattag tatagcaaaa tcacaagcca
    23881 aaaacaagga ttttctaaaa aataattcaa aatatataga gctatcacag caccaaggaa
    23941 aatgctacta aggtcatcag caatcctcca acacaattcc aaaaataggt cttaagacct
    24001 attgtatttg tatcaaaaca atagcacaat aatatcaaac acaaaggaga gcgtttatga
    24061 tgaatgatat aactagaaag attaaccata agcaactgat tcaaatcact accattctag
    24121 gcattattgt taccatcgtt attttgttct atctgcagca gcaccctaat ctttttgcag
    24181 ttggcggtcc ttttcagacc tatcttatgg aacttggtat cctagcaccc tgtttgttta
    24241 tactgcttca aatcattcaa gtggtttacc ctatcattcc tggaggcttg acctgtgttt
    24301 tagggcatgt agtctttggg ccgttttggg gatttcttta taatactcta ggtattttta
    24361 ttggttcgct gcttagcttt atgctcgcta gaaaatatgg tgaacagttt gctaaagcct
    24421 ttgtatcaga tgatacctat aacaaataca ttccttacct caataaaggc aagtactttg
    24481 aacgatttct cataacagcc tttattctcc ctggctttcc agatgatttt ctctgtatgg
    24541 tagctggact aagcagcatg tctatcaaaa catttaccag tattttcttg atatcaaagc
    24601 caattactct ttatatctac acccttcttg cttaccaagg catacaaatc gttggacagg
    24661 tattgcaatc ctaaaaaaag ctagtattaa gctatcaagc ctgattggaa tacagtattc
    24721 caatcaaaaa ggcgctcagc ttggtaccag ctttttatcc ttgtcttagt tgctccaaag
    24781 tcctttggaa gatttctggt ggctcaacag taaagaccag ctcctctcct gtcacagggt
    24841 gggttagtcc caatgtttgc gcatgaagaa actgcccctt gccagccaag gtcttacgag
    24901 gaccgtagag tggatctcct gcaagagggt gaccaatata agccatatga acgcgaattt
    24961 gatgcgttcg acctgtttcc aattgtaatt ccacgaaggt atagtggcca aagcgctcca
    25021 aaaccttaaa aagagtcaag gcttccttgc ccttagcagt tacggtctgt tttttacgat
    25081 ccttttcact gcggccaatc ggagcttcaa ttacacctcg atcctttggt aaattaccat
    25141 gaacaatggc cacatacttt cgtaaggatt tcttagcctt gagctcatca gctagtagct
    25201 ggtgggcctt atcggtcttg gcaaccatta aaagaccaga ggtatcctta tcaattctat
    25261 gcacaattcc tggacgaata acaccattaa tagaagacag gtctttgata tgatagagca
    25321 aggcattgac cagcgtccct gtagaatgcc ccgcagaagg gtgaacaacc attccctgag
    25381 gcttattaat aatggccaat acatcatctt ggtagacaat atctagtggt atatcctgag
    25441 cctgatagtc caagctgctt tcctctggga tatgatagct aatgcagtca cccacctgca
    25501 caatatactt ggccttctta ggtaagccat tgaccaatac ccttttttgc ttgatctgat
    25561 cattagcctg acttcttgat aatggggtca aatcagccaa ggccttatcc aagcgatggc
    25621 ctgattctgt tatcttaatt tccatagtcc tcttctttcc atagacaaat gaccagcagc
    25681 aaaacaccta tcgtcaaata ggaatctgcc acattaaaaa tagcaaaatt gatcacatct
    25741 aaatgaatca tatcaaccac ataggataac ctcaagcggt caataaaatt cccaagacct
    25801 ccagatataa tcagcaataa agagagctgt agccaaaagc tagcctttgg gtgcttcaac
    25861 acataataaa tggcatagcc aaccaccaaa acagttatga ttgtaaagaa ccactgctga
    25921 ttctgtagta tggaaaaagc agctcctcga ttttgaagat aggtcaagct caccaaacct
    25981 ggtataaagg gcttcacctg ccctagctca atatgtgtaa cagtccacca tttacttagc
    26041 tgatccagta tcattaagac aatggcagcc ataataaaac taattctttt caactaatcc
    26101 tattcctttc agcttaaaaa caagagatta ccttgatggc ttcaaaaaag caacaacagc
    26161 cagctgtctc tgtagcgtac tcaaccttaa agcctccaaa aactggtatt ctagtaacct
    26221 tttagtatca ttgatagtca accacacagc agctctagac ttgactttat atcaacaagt
    26281 ctcaccacag cagctcgctt aatccttatc cataccagag ctaagtccca ttgtctatag
    26341 cttgcttttc ttttcgatgt tcaaaataat cctgtaaaat ggtcacaaaa tgtaaagccg
    26401 cagcagatag gttcttatcc ctacgcttga cataaatcat tttatgctcc atatgatcac
    26461 gcaagggaat aaccttgatg ccattaacgc tttgctgatc taaaaatcca gaccctgttg
    26521 caaaggcagc tgtcctttcc aaaatgccat ttaaggttgc cctatctgac acagtgtata
    26581 tgtgaggact cttgcttgtg tcaataaaat tttctgaata ataaagatat tcttcttttt
    26641 cttgagtaaa gcgtaccgct ggcagccctt gcaaatcctc taagaaaagg gctttccttt
    26701 gagccaatgg atggtttttt gataggtaaa tatgggttgt aaaggatagc aattcaacat
    26761 aatccaaagc cagcttatcc attcgctgaa aaagcccctg acggttttgt gcattaagat
    26821 agataattcc aagctcacta tttccctgtg ccacctcatc taaaatttgc atagtcgttg
    26881 actcaaaaac tctaaaaacc ttatgcccag catgcttttg ggaaaatgct gttattaaag
    26941 ctggtaaaaa atcataatgc tgactcgcaa ttgaaaattc atttggctcc aaagccgatt
    27001 gagaaaactc cttttccagc gagtcaaagc acttaacaac ctctaaggcc ttttcataaa
    27061 ataaaagccc ctggctggtt aacacagttc ctgctgttgt cctacgaaag atctgaaagc
    27121 caagctctgt ctccaaatcc ttcactgaaa cagacaaact gggttgactg acaaatagct
    27181 ttgaagcagc ctcacgaaag gtaccattat ttgcaatagc aaccacatat cgtaattgtt
    27241 gaatattcat taatccactt cctaaatcta gtacccttca ttataccata aagccagcca
    27301 atgaaaaata aaggcgtcca tcttaaccat gccaaacgta tctacagata atcatgagat
    27361 agcattgact ttttcaatag tgtcttatca tatttagcta tagaaaacag ccttactata
    27421 agttatactt ttgaaagaag taagccttag atcacagaac atcacactga gattttttat
    27481 gcgcttatcc tgtctgtcca agaactgaga attggctaca tctagctaat aagccatttc
    27541 aggattttac tgtctaggag ttatttatag gcaactatta cagtaagata gtgtcacaat
    27601 acaaaaaagg ctatcccaaa gtacagaaca gccttatacc gtgccctttt aacacattat
    27661 tttgcgattg ggtatacaga aacttgtttc ttatcgcgtc ccttacgctc aaagcgtaca
    27721 acaccttcaa ccttagcaaa aagagtatca tctccgccac gaccaacgtt aacaccagga
    27781 taaatatgtg tgccgcgttg acggtaaagg attgaacctc ctgaaactgt ttgtccatca
    27841 gctgccttag cgccaagacg ttttgcttgt gaatcacgtc cgttagaagt tgaacctcca
    27901 ccttttttgt gggcgaagtg ttgtaggtta gaaagattaa gtttaatcat ttttatttcc
    27961 tctcgttgaa tttaattcat cacaggcttt tgaacatatt ctgataaatg ctctgccaaa
    28021 ttctccaagc caatcacaac agactcaaac agaatttgcc acacctgctc ttgttgctca
    28081 gtaaatccct caggctttgt tacccttagg aatccaccac catcgaccat ttctagtgct
    28141 ggctcaagac ctgtcatctg ttcaactgaa ttaacaagat tgaaggccaa aactgaaacc
    28201 gaagcacaaa ctacatcaaa gccgtactca ccgcttccag catgtcctgt gataagcatc
    28261 tcagtccagc cagctgcgtc ttttgttaac cgtactttaa tcatgtcaaa ctagaattat
    28321 gccttgatag cgttaatcac aactttagtg taaggctgac gatgaccttg cttacggtgg
    28381 ctaccttttt taggcttgta cttaaaggtt acaaccttct tttgttttcc ttgcttttca
    28441 acagttccaa cgacagtagc tccctcaaca actggagtac caacgacagt cttatcacca
    28501 cctacgagaa caacctcgtt aaaagtgatt tctgcgccag cttcagcgtc aattttctca
    28561 acgtagattg cttgacctac ttcaacttta acctgttttc caccagtttt gatgattgca
    28621 tatgtgctca tgatgcacct cctataagat ttttgatgag gtttccctct gtgaagactc
    28681 gcctagaatc gtgagagcca atctacttga aaacgatttt cgtgcggttg cacaggacgt
    28741 gcacttagtc aacgttacaa ttttaacatc aaatttgatt tttatcaaga aaaatatgct
    28801 tttatcttcc taaaatctta agctatacat aatcacagct atgtaaaggc tagcaatgct
    28861 ttaccatttt aggttaacca gggcattcat ttctttataa gcaatagctg ctttttcttg
    28921 cgtttcggga tcaatcttat cataatatct gccgcctttg ataaagtcct ccaaaaccat
    28981 ggtacgatag ctatatagct catagccttc actaccataa aggcccttag gcttagctaa
    29041 aaccattgtc gggtgagcct ttactgtttt tatttttgtt ttttgcccct tcttctcaaa
    29101 ggtaaggtcc attagcacgc cgcgctctgt ccaaatatca tcaacagtct ctaggcgttg
    29161 attggaaatg aaattaccca ttgaatagat aataaatttc ttttccttgt ccttaacaat
    29221 cgtctctgcc ggctctacga cgtgggggtg acctcctaag acaacatcag caccccagtc
    29281 aatcattttt cgataaagag ttttttgctc agctgttggc tctaaagcat actctgtgcc
    29341 catctgcggc ataacaatgg taatatcggc ctctttttca gcacgcaaga tgtctttttg
    29401 tatcttttcc tcattaaggt cagacaggtg cttgtcatac tcctcctgac tgagtgtcgc
    29461 ctccattcca ttatagccat atgaatagcc caatattgca atcttaatcc cattaacctt
    29521 tttaatgaga atgttctcct tagagcgatc ctgctcataa ataccaatgc tgtctatccc
    29581 catatcagca aaaacacgct tggtattgag agctccttct aatcttgagt ccaaaatatg
    29641 gttatgggcc aaatcaacca catcatagcc agtatgctta agcgcagcag caatagcctc
    29701 tggcgcatta aacaaaggat agccagctag aggatagtct ggactgatcg ttccctcata
    29761 gtctccaatg gccaaatcag cctgactaat ccaatccttc acatactcaa aatagggatt
    29821 aaaatcatag ctaccatcag cctttttagc actcatatag agaatatcat gaatcaaaat
    29881 atcaccattt gcgacaacac gcgctgtttg tgtcttttga ggtgtcttgc ttttcgtttg
    29941 tgtgcctttt tttgacatgc ctaataaatc aaaggccaac ccaaaaacaa gtatcaccac
    30001 aatcaaggta agcactgaaa gcatggtctt tttatactga aaatctttta gcaagcgtca
    30061 aacctccttt tttcctatta taccatgttg acacgacttt ttaataacaa atcccaaaga
    30121 aaaggctatg cccatttaag aagaatgcct tagacagcag catagactcg tattagctag
    30181 tcaaaaaact agattgctcc tctttggttg atgtcatata ctttgagcct aaatagcttt
    30241 caacaaagtc taatagttga ataatgtcat gcaaaatatg gtataatgaa acaaaatcaa
    30301 actagtcagg atagtcacat gaagcataac tctttcagcc gctcactatt actccccctt
    30361 ctcatctgtt ccttgtctgc ttgctcttct catacagaga aaaaagacca taccaaagac
    30421 gctactgcta tcaccgatac ccgaaaagca gagcatcagg acatcagggc aaatatggaa
    30481 aaggtcaagc tcgctaccgc tagcaccgac ttcaaaggtg gctcaagcct tgaggagcta
    30541 atcactattt ttggacagcc tagtcagcac gaagaaaaag cagctggtag tgttactctt
    30601 gactcctaca catggcagtt tgaccatgtc acggttaata ttaacctcta tgaaaacagc
    30661 agcattgtta aaactattgc taactttgct tttattagag acctgacctt atccttaaag
    30721 gactacaaca gcttgaaaaa gggcatgacc tatgatgagg tcaagcagct attgactgag
    30781 cctgataatt acagtcaagc caattccagt gaaaaagaaa ccattcaagc catttggatt
    30841 agtggcttaa aagctcagac acagggtgcc aatatagcac taacctttga aaacaaccag
    30901 ttgacagaaa tgtcacaggt tggtcttgaa gactagtttg tggataaccc caatcatatt
    30961 aatgatagaa aaaagcttga tatttaataa gatcaagctc aaacgataga ccaagtagct
    31021 gatgatcttg acagtaatgt gtaacaagct gagatactac tcactaggca gtatttacta
    31081 gcagccactg aatttccttt atgatgacag gcaaccacct tttttgtggt gacctatcaa
    31141 tagcaccata agctctcttt tgtcacatac cttgcttaac attattttac caggtatgtg
    31201 atgagctttt taggttgtct gatagtataa catctaaccc ctagttgatg atgtagataa
    31261 ggcaagagct gctaaggata gcaccataaa taagatccaa catagggtca tattatatag
    31321 tgccaagaac gaaaagataa agacacctac agggagcgat aaagagaaca gaagacctaa
    31381 aaagttattg ctttgggcta gcatatctga tgggagattt tccattaaaa gggcgtccag
    31441 cttgggtgtg gcttttccca taatataagc tgcaaaggct aagcataaaa cccctatgat
    31501 ggcaggtaat tgcagagcat tagagactcc taccagcaaa aatgctatgc cctgagtctg
    31561 tactagcttt gatattgaaa gccttgaaaa gtaatccttt ggtgttagat ttcccaacat
    31621 cgctccgata atcgtaacgg catcaacaat aactaaagac tgcccataat gaaaatgaaa
    31681 tagctgatga tccatcaaat aaaaatgata aatgctatta attgctcctc caatagcgtt
    31741 taaggtcaag atggataaga gtaacatcac aaaagagata tgatcaatct ttttaaaggt
    31801 ctctgtcatc cttgtataca tcaccttaaa ttgcttcatt aatgaaacac ctgcttcaga
    31861 agcttcaacg acatcatgcc ttagcttttg tcgattttta agaagcacaa cagatgacaa
    31921 taaaaaggaa atagcattta tcaaagcaac aaaggcataa ttgttgcctg atgtcgttag
    31981 cagccaaact cctaaagctt gtcctgcaat actagagagg tagccgataa attgagcaaa
    32041 agaataggcc tcatagagct tttctgattc aatatttttc tgcattatcg ggagacgtaa
    32101 gccatttttg taatcactta gaatatcaga aaccacattc aaaaagccca caaaggcaaa
    32161 taccaagaac gtctgatttg tcatcaacaa ggctacaagc gtaaataaaa gagattgtat
    32221 aaaaccaata acaataagat ttcttgtttt cctttttgtc ttatctgctt tgacgccaat
    32281 ccaaaaggta aacaccatag gaatgatggt gatgatattg gctataaaaa cagcaatatg
    32341 agaataaggt agcgtggttg cataaataat aaaaacaata ttgtaaatat aagagcctaa
    32401 agcacttaaa aagtttgaaa ctgtcagtgt tctaaaaacg acatttttaa tcaatcccct
    32461 catttactta cctgttgacg tcctttctta tgtcacctta ctttacttga ttgaatatac
    32521 ttacagcata tctaaattcg tactgtagtt ttatatggtg ttctgacatg attttgctac
    32581 taattagtaa ttcacaagcc ttttctaagt ataaagtatc gtttgttagt ctaaatactt
    32641 gtaaaagtgt catggctatc cccagcattc cgttccatag accactaaac tgagcaaatt
    32701 caactaataa cgactccgat aaattcttaa tatctttaat atatttatcg gagttaacgt
    32761 aaataagcaa ttgaacgatc ccagcagtcc catttgataa gtatggagat acagaatttt
    32821 ctgatattaa tacaccccga tttccatcgc tatcttcaac taagctttct agaataaaat
    32881 caattccttt ctcaataatt tcgttatcat aagaaatt
//
LOCUS       DARYYD010000021        32748 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.021, whole genome shotgun sequence.
ACCESSION   DARYYD010000021 DARYYD010000000
VERSION     DARYYD010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32748
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.021"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            376..1131
                     /locus_tag="TV188_000910"
     CDS             376..1131
                     /locus_tag="TV188_000910"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEL1534284.1"
                     /translation="MGNDIIADFLNKGCQKSNFIVGPCAIESYQQIRQAAASAKALGY
                     RYFRGGAYKPRTSSNSFQGLGLTGVTYLHEVCQEFSLKAVSEIMSERQLEEAYDYLDI
                     IQIGARNMQNFELLKVLSKIDKPILFKRGLMATIEEYLGALSYLQENGKQNIILCERG
                     VRGYDVETRNMLDIMAVPIIQQKVKLPIIVDVSHSTGRRDLLLPAAKAAKAIGANGIM
                     MEVHPTPDLALSDAAQQIDYQQLEQLGKELWES"
     gene            1190..2272
                     /locus_tag="TV188_000911"
     CDS             1190..2272
                     /locus_tag="TV188_000911"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEL1534285.1"
                     /translation="MTQTLQVKSRINDYPIIFTDDIFQPLNQFLAEKGDVKLLFITDQ
                     TVFDLYQPLFRRFQQDYDSYLHIAAPGGQSKSLEEVSRIYDRLIRANFSKKDVIVTVG
                     GGVIGDLGGFVAATFYRGISYVQIPTTLLSQVDSSIGGKVGVHFKGLTNMIGSIYPPN
                     QIIVSAKFLDTLSEREFACGISEMIKIGFIHDRKLFQQLLAFPKDRNQEQLRQMIFQA
                     ICHKKRVVEKDEFEGNLRMSLNFGHTLGHAIEALCHHELYRHGEAIAIGMVFEAKLAV
                     QQQLLSQQDLEALQAAFEAYQLPTTLEAKSMTAEALMTVLKTDKKNSGQHIVLILPTT
                     KGYVSFPIAKHDSRLLDWLRSLLDIA"
     gene            complement(2604..3377)
                     /locus_tag="TV188_000912"
     CDS             complement(2604..3377)
                     /locus_tag="TV188_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEL1534286.1"
                     /translation="MILTQFDPDYQAIINPKDLVAEIDDFPKTVVTCFARATFNRVLN
                     ALPHRLIATTSVANLDIPIYELDVKGHKLGFFNSYVGAAGCVGVLEDIIAMGMKQLLV
                     FGTCGVLDATISENSIIIPTSAIRDEGTSYHYQPASHDIAVNQAYLTRAIDVLEQHSQ
                     TYTLGKTWTTDGIYRETRDKMIQRKQEGAICVDMECSAIAALAAFRQLEHFQFFYSAD
                     NLDADEWDARSLANEADLEAKDNIAFIALELALRLFKDN"
     gene            complement(3503..4387)
                     /locus_tag="TV188_000913"
     CDS             complement(3503..4387)
                     /locus_tag="TV188_000913"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEL1534287.1"
                     /translation="MLERLSGQTRLTALLAAPARHSLSPKMHNAAYAKLGLDYAYLAF
                     EVGNAELAAAVQGMRALGICGANVSMPNKQAIVPLLDELSPAAALAGAVNTVVNKDGR
                     GHLVGHITDGTGAIRALAEEGVSIKDQIITIAGAGGAGTAIAVQLGLDGAKEIRLFNR
                     KTATFKQAKQLVARINTQTSALASLQDLADDRAFRRSISESSIYIDATGVGMKPFEEH
                     RLITDPALIRPDLVVFDLVYHPAETKLLAFAREHGAKKVMNGLGMLLYQGAEAFKLMT
                     GEDMPVAYIRELLCQNKE"
     gene            complement(4538..7981)
                     /locus_tag="TV188_000914"
     CDS             complement(4538..7981)
                     /locus_tag="TV188_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2 protein"
                     /protein_id="HEL1534288.1"
                     /translation="MSVETITGSTDQSHGDIYQLHWIDKVGRCHAFSKGWRFLMADLQ
                     LAQEPFFDDSDWQQIALPHDFSINQPYTVNGEAQSAYKLGGVGWYRKYFALDPKLADH
                     KVYVTFDGAYMETQVYLNGHLIGEHVNGYQAFSYDLSAFVIPGQENLLAVRVEHLVPS
                     SRWYSGSGLYREAFLTVLPKVHLDKDRLRLSLSQAALEADSQALEIELGLSQQVPLSG
                     YQLSLSLFEQLADIQQRQTVYESKPVALDLLEESGRLVMTIPLRHIKLWSPAQPQLYQ
                     LDMLLYHKGAVLDRLTLETGFRQLHFDAECGFFLNGKAFKLQGVCLHHDQGSLGACAY
                     EEAIARQLVLLKEMGANTVRVTHNPSARRLKDLANRLGLFLIEEAFDTWTYAKNGNSH
                     DFSSHFHKTVGHQNAARLKGVTTAETTWAQYSIQAMVLSGLHDPSVLMWSIGNELLEG
                     FSADVSHYPYVAKELCQWITELDQSRPITLGDNKLKDKHFHWAQETKALAEQVNQLQS
                     VQGVIGLNYAKARDYDRLHRDNPTWLLYGSETASAINSRGVYHLKGGASQDHELTSYD
                     QSTVDWGSLASEAWYDTITRDFVAGECVWTGFDYLGEPTPWNKIDSGAADQWPSPKQS
                     YFGILDTAGFAKDSYYFYQSQWSKDKTTLHILPSWQEKDLQLDDQGMVEVVVYSNAAS
                     VRILFDDGHGGQIDYGIKTLTRHETPAGHCYQLYEGDDAAELPHQNLYLTWKLPYRSG
                     SLRAIAYDDKGQVLTQTSGRSCVSSYQQPAQLSWSCFEPPKLLAEPALLYLELSLLDA
                     NETLVLSANPVIKLEVEGPGACLALDNGDPRDHRPYTALSRRAYGGKLLAIIALDGRA
                     GQLRITARAAGFVEASYQLTVSEAAVNEKLLAYQLDKYSFITNETNKPSKPYARSRGS
                     AVDSLMPNPDSCLKRQGHYLPDNSVMVFSYTTALSRPLTFQPLIKRLLKGNDIILPDW
                     LQPRAAAGQLFTKAFPIDWQLTEAVFSEESRVSGQTLCFGEALELEAILKSDTKGLRI
                     NQELSLVAKKKRLFQSDTQLSYRYQYDTIQAIGAISLTGLKKPLSSLRLVLDYRSSTN
                     APSKQLILSLDQIEQPCHYIMLEEVVDVLSLDLTLEQPIRQAFDLARLQLGLWSMVEE
                     A"
     gene            complement(7995..9479)
                     /locus_tag="TV188_000915"
     CDS             complement(7995..9479)
                     /locus_tag="TV188_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1534289.1"
                     /translation="MYKVLLVDDEYMILQGLKVIIDWQALGFEVVATARSAKEALAYL
                     DDCAVDVMISDVNMPGMTGLELIEAARDVLPHLQTLILSGYQEFSYVQRAMELETKGY
                     LLKPVDKKELVAKMLYFKEWLDEQRAASLRQAAYREGLINLWLADELSEKEFFQLTQE
                     QPEAELLGFTVLYVDCKTFSPALEAFFEASKQPFYLKKAEQKKVYLVILLGQSHQAKR
                     FTNTLQERFYNTINQIILGETVVDWENVYESYNQVRRSFFYNSEVSQVAAKTNAKIEL
                     PESRLQFFSFNKTLMIGDEPTIVSKLQAIFEEMTELSFSPEDVKHVSFLLFSDIYRQF
                     PILDRTTYLSMVKTIHDSQSIDQILSALKKVLELTSKSNQPQKRYSDLVSEAITCIQE
                     EYSQELTLKAVSDRLHINGVYLGQRFKNETECSFSQYLNQVRIQKAQQLLLYTNKSIN
                     EIAYETGYNTNHYFIKMFKKLNGLSPKEFRDRYKDNYQAIKGSY"
     gene            complement(9479..11203)
                     /locus_tag="TV188_000916"
     CDS             complement(9479..11203)
                     /locus_tag="TV188_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1534290.1"
                     /translation="MTSKSLKRFLMEHIKQGFLINRLMKIYSLFIVALFSLSAVGLST
                     YSIRNTYQMVDNQMQMRLDETLARLQSQNYITLRVLEQLIGRPEDYRNLYQYMILTPN
                     QYLTKVFEDWGEGKNTPLFSEQVRRLFDLYPDLDGLTLMLDDSTSYLYADRSIKTGRL
                     LFGKPQTLKGNYLVRSIRHPESGDVTGRLYLHFASPSTMLQPEQHKYLATFAFDYYGR
                     ELFHQGGAAFPELEAGLKKALKADQAIDLTALSKSYHIQYNRSGDLLAYVAVKRSYFM
                     EEAVRTMLLYGLGSLLLAWLLLQLLFRVFRNYIRQVSEITDTIEMVAAGDLSLRIDNS
                     HMELELYHISEAINQMLGNINAYILEIYVLEVEQRDAQMRALSSQINPHFLYNTLEYI
                     RMYALSCQQEELADVIYAFAALLRNNISQDKVTTLKEELAFCEKYIYLYQMRYPDSFA
                     YHVKLDPVVADVEIPKFIIQPLVENYFVHGIDYSRYDNALSIKALDEEDSILIQVLDN
                     GKGISPERLVAIEKGLEEPQSTGNSSIGLQNVYMRLFHKYRDRVTWSMSQAPTGGFRI
                     QIRIRKEA"
     gene            complement(11193..11798)
                     /locus_tag="TV188_000917"
     CDS             complement(11193..11798)
                     /locus_tag="TV188_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HEL1534291.1"
                     /translation="MTGIEKACFLIWKMMQLTLIFHLLSLCGAVIFGVGPAWQTIVTL
                     FLETSQQEKHYSLKRAFQIWRRVFKEANLSFFFFGLLLLLLNTSLYLAIQFQSLLWFS
                     LSFIIMFVMVWLVMIVIYMTFYAVTYEIAFWENLKLSFISIFLNARQFLLTLVVLAGV
                     AWFTWQYKGLYLFLSFGALVLLLDMVTKPNRRMVDGVIDDK"
     gene            complement(12146..13591)
                     /locus_tag="TV188_000918"
     CDS             complement(12146..13591)
                     /locus_tag="TV188_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEL1534292.1"
                     /translation="MKKWQTILCVTGAVLAAASLTACGSKSASKDGEVKLLMYQVGDK
                     PDNFDELMTIANKRIKEKTGATLDLQYIGWGDWDDKMRIIIASGENYDIAFANNYVVN
                     AQKGAFADLTKLMPKYAKKTYKNLDPAYIKGNTIDGKLYAFPVDANVYAQQMLSFNKE
                     LVDKYGLDISNINSYADAEKVLKQFHEKEPNTAAFAIGQVFSMSGDYDYPLTKNQPFA
                     VKIDEGKPTIINQYEDEPFKANLRLMHKWYKEGLIPTDAATNTEGYPLEGNTWFMREE
                     TQGPMDYGDTILTNAAGKDIVSRPLTKPLKTTSQAQMANFVVSNVSKNKEKAVEVLSL
                     LNSDPELLNGLVYGVEGKAWEKVGDKKIKLLDGYQPKMHMGAWNTGNNKILYTQESIT
                     DDMIAKRDQSIKDAKESPILGFTVDTKAIKTELSKISNVMNRYKASINTGTVDPDEAL
                     PKLLSDLKDAGWDKVQKEVQKQLDDFVTKNK"
     gene            complement(13675..14601)
                     /locus_tag="TV188_000919"
     CDS             complement(13675..14601)
                     /locus_tag="TV188_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003044580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEL1534293.1"
                     /translation="MEKKKTVKRVNVRTFDPKTNAVFNVLIALFAISCIIPFIFVMII
                     SFTDESYLINHGYSFFPAAWSTKAYHYIFQGAMSHRIIRSFAVSVFITVLGTFINTTM
                     TSTYAYAISRPYFPYRRFFTIYALITMLFAPGMVANYLVVSNLLQLKDTVWALILPMA
                     LGPFGILVMRTFFKKTVPDSIIESARMDGAGELMIFMKIVLPLAVPGIATISLFSALT
                     YWNDWFNALLYVQSESLYPMQYLLMKIQSNIQALAQNAGMSAQLSDSLASLPKESVRM
                     AIVVIATLPIALTYPFFQKYFVGGLTIGGVKE"
     gene            complement(14611..15561)
                     /locus_tag="TV188_000920"
     CDS             complement(14611..15561)
                     /locus_tag="TV188_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004219264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEL1534294.1"
                     /translation="MTTKISSKKSFWKNVIKYRALLLMVLPGFVWFIFFFYIPVLANV
                     VAFKDFHYSAGGFMESLKESPWVGLDNFKYLFASKDAWLITRNTIAYNLIFLLFNVFF
                     AIAFAIIMSELRNKKAVKVYHTMSLLPYFLSWVVIEYFVSAFLNTDKGFINQLLIDSG
                     NSPIKWYSNPTWWPLILLFMSVWKGLGYNSIIYYASVKGISDTYYEAAMVDGASKWQQ
                     IRHITIPQLLPMMSILLIINIGSIFKSDFGLFYVIPKNSGPLYDVTSVLDTYVYNALT
                     ATGDISMASAASLYQSVVGTCILLITNAFVRRMDPDAALF"
     gene            15773..16666
                     /locus_tag="TV188_000921"
     CDS             15773..16666
                     /locus_tag="TV188_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1534295.1"
                     /translation="MTLLCIDIGGTSIKFAICHKGRLKKQSSRPTPQSLEDFYHMLDE
                     RLAYYRTEKLSGIAISSPGAVNKATGIIEGASALPYIHGFPIQQCLEERLGLPVSIEN
                     DANCAALAESALGAGQGTSSLAMLVLGTGVGGSLVINGRIHYGAHLFGGEFGFMVMNE
                     RYQTFSELGTVVNMAKRYSQIINDGKSYTGKEVLELADQGDPVALKERQVFLQSLAMG
                     VFNIQHAFDPEMILIGGGVSQADFLLPALEAELDKLYQIVSISDLRPQLAICHFKNEA
                     NLLGASIDFMQEHRKDEMWID"
     gene            16654..18828
                     /locus_tag="TV188_000922"
     CDS             16654..18828
                     /locus_tag="TV188_000922"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEL1534296.1"
                     /translation="MDRLDFIDTRFGTTNHYHFSQGNCLPLTGVPFGMHYLSVETSQD
                     RGAWWFHPDDHSFSGIRLTHQPSPWVGDFATVTFLPVSGPLTKGDVFHNQTSYRPKEA
                     AFRPHLLEIFSQRHRILTRATAAAYSFHCDFSFDNGKAGLIIHNPGKSSWQVTADGKT
                     ILGCVQNITDCQDKDLAMFVYLQFSSPVLKKLIGEDLNSKSLDDCSKTSFTYLQFADD
                     LKHLELRAAASFISFDQAQLNWQRDFPRSFEKSLEYSRKEWLSYLSRIDIKDKDFDKV
                     KAYYQHFYRALLFPQRWYEITATGQAIHYNTTSQRPVAGKYYTNNGFWDTYKSVYPLL
                     SLIAPEIYADILEGLLSAYQDTNYLPKWLSPDERGLMPGTLVDAVIADGAVKGIRKDL
                     MPELLEAMLATANTDSQGTGYGRKGNQDYQELGYLPNSYQESVNQTQDYAYSDFCIGQ
                     VAALLGKTALSDQYHTRSLNYRHLVDTDTGYLKSKDRQGQWQCGFNPIHWGQDYTEGS
                     YYQNGFAFYHDILGYIRLIGGNAAIAKRLEELCNHEPVFDVHSYGFEIHEMSELAAQD
                     FGQIAISNQPSFHLPYLYHYIGQPQYSQLILKNLLSHAFTDTGYPGDEDNGSMSAWYL
                     LNSLGLYPVTPGTGQYLIGIPTVDQATLYLPNGNTIQISCRGNVPQYQFVKEVKLNQA
                     SYNKLYINHDDLIQGCQLDFQLGLVPPLKHYSAEDLPYSLTR"
     gene            complement(19024..19161)
                     /locus_tag="TV188_000923"
     CDS             complement(19024..19161)
                     /locus_tag="TV188_000923"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534297.1"
                     /translation="MELAKKRRKTQKPAQSPLKLGLEKLREILQEQLVALAVLPARVM
                     G"
     gene            complement(19148..20539)
                     /locus_tag="TV188_000924"
     CDS             complement(19148..20539)
                     /locus_tag="TV188_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1534298.1"
                     /translation="MLEFPEGFWWGSATSGPQSEGCFQKPHRNLFDYWYEQNPELFYD
                     YVGPDTASDFFHQYDQDLALLASLGHNSYRTSIQWTRLIDDFETATINPDGLAYYNRV
                     IDACLAHGMRPVINLHHFDLPIALYQKYGGWESKHVVDLFVAFARVCFEQFGDRVKDW
                     FVHNEPMVVVEGSYLLQFHYPAIVDGKKAVQVAYNLALATAKVICTYQEQAAELSNGS
                     VGTILNLTPIYPATDSEADLAAAHVAELWHNDLFMSAAVYGSFPKELVAILQRDGVLW
                     QSTPEELDLMAAYTVDYVGINFYRPKRVKAPEVIPVISPSWSPEWYYDAYLMPQRRMN
                     VDKGWEIYPEAVYDIALKMRDQYRNIPWFLSENGVGISGEDRYRDESGQIQDDYRIQF
                     LKEHLTYLHKGIQAGSNCFGYHVWTPINCWSWLNAYKNRYGLVENNHRTQRRRVKKSG
                     YWFKEVAEANGIS"
     gene            complement(20566..22260)
                     /locus_tag="TV188_000925"
     CDS             complement(20566..22260)
                     /locus_tag="TV188_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylglucosaminidase domain-containing
                     protein"
                     /protein_id="HEL1534299.1"
                     /translation="MSIYQALKDYQEVITRGDYLVFDAPVSCRFVGRFFRFENQTAMK
                     PSLTASVYVNWVEEGAADLTLKHVFNRTLARDAFTLTISEDKELVIESQNLRGFRYAQ
                     EALEKVMTVKEGRLYLPIVSVRHSPSFAMRGVIEGFYGTPWTREERLDCLSFIADKGM
                     NTYMYAPKNDDYQRSHWREPYPEDWVAHFRDLIQLAKERQVDFWYMISPGLDFDYTKE
                     EDYQLLYQKLQQLLDLGVCHFGLLLDDIDYQIVAAVERRFKKTAYAQAHLATAVYQFL
                     QRQHAAPDLVVCPTEYDNHHDSLYLAELSEAIPAEVAFFWTGPSTLASQISQADIETI
                     AAIYRRPIIIWDNIPVNDYQDDSKRLFLTPFANRSPFLCQPDYQVRGIVSNPMISWEL
                     SKPTLIDMSRYLWDAKRYQPSYSWLEALRDYTGDKAMALALLRFAWHNGNRHLHRDLP
                     FEVEEALMRKDIASLSGWVAELVELVDKLKELDIPAFQQAIAPWFDRAKADQSFWRVI
                     LEQAPDLEQQYAELQEQRHRIGSNIPSRFYQLHYLQENSMLGNQAQVAEARAEDYT"
     gene            complement(22275..23333)
                     /locus_tag="TV188_000926"
     CDS             complement(22275..23333)
                     /locus_tag="TV188_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1534300.1"
                     /translation="MTELLYKKIYHFIKEQIDSGQLQAGDRLPTEKALSEQFSVSRIT
                     SKRALVELEQEGLITRSRGKGSFVTDGPPPSTQPNKDILLILPFASDYELGDYAKGIM
                     TVVADKGYRLMVQLTSTVSLEELADYAGVIYYPEDVNHSIELLFYCAQRGLALVLLDK
                     ALDLFDFPAVVADNKGGAYELTKHLIDQDCRRIMFVATASFGEVSSVRDRYLGYLAAM
                     AETELEANYFVKLKSESNAAYLERLVDELTAATAEKTGLVVENDWLAIQLIQKILQVG
                     LSIPDQVAVVGFDNSQASQLISPQLTTAAQDFYQMGQQAAQLLIERLTRPDQQTASCQ
                     LPVKVFIRESSQKSLEML"
     gene            23466..24752
                     /locus_tag="TV188_000927"
     CDS             23466..24752
                     /locus_tag="TV188_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEL1534301.1"
                     /translation="MTRPIPSSVLRFMDTIEELCGEEHRSWAINFKASFANTLETTLK
                     IDEDGTSFLLTGDIPAMWLRDSTAQLKPYLFLAKTDAGMRQIIAGLVKRQFRYICIDP
                     YANAFNEEENSKGHQADHTQMGPWIWERKYEIDSLCYPIQLAYLLYRETDCTEHFNED
                     FHRGIKLILDVWSTEQDHTASPYSFERDTWRKEDTLTHNGKGAPVAYTGMTWSGFRPS
                     DDACQYGYLVPSNMFAAVVLSYLEGLYTDLFKDQTIARRAHALRLAIQKGIEEHALVT
                     NSQGEIIYAYEVDGLGHYTIMDDANIPSLLAAPYLGFCAKDDPIYLATRQTILSPENP
                     YYYQGSAASGIGSSHTPPNYIWHIALALQGLTALDQKDKADILDLLVATDAGTHLMHE
                     GFDVNDPSHYTREWFSWANMMFCELLLDYLGFTISP"
     gene            24767..27493
                     /locus_tag="TV188_000928"
     CDS             24767..27493
                     /locus_tag="TV188_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEL1534302.1"
                     /translation="MTPKKVHIISHSHWDREWYMAYEQHHMRLIQLIDDLLDLFKTDP
                     DFHSFHLDGQTIILDDYLQVKPGREAEIRQAIQAGKLRIGPFYILQDAFLTSSESNVR
                     NMLVGKEDCEQWGASVPLGYFPDTFGNMGQTPQLMRKAGLNAAAFGRGIRPTGFNNQV
                     DTSEKYSSQFSEMIWQGPDDSRILGLLFANWYSNGNEIPTEEKKARQFWDQKLADAER
                     FASTRHLLMMNGVDHQPVQLDVTKAIALANKLYPDYDFVHSCFEDYLADLSQELPEEL
                     SIVSGEMTSQETDGWYTLANTASARIYLKQANTRVSRQLENITEPLATMAFEVTGTYP
                     HDQLRYAWKTLMQNHPHDSICGCSVDSVHQEMMPRFDKAYEVGTYLAERSANQIAEAI
                     DTSMFPEDSCPFVLFNTCGHEKKTVSDLTLTWKIFPFGQRLPKAVYQEAKEYLETRQP
                     QFQVIDAAGRIIEEAEILGTDIAFDYALPERTFREAYFAIKVQLRLPLTLSAMSWQCL
                     ALKETDQPCQATDTDKMLFHQDRSCLENDFLKVIIAANGLLTIEDKLNGNRFDSCLQY
                     EDCGDIGNEYIFRQPDHDSPYLAHQGSCKLRVLTNTAYLAEIELTQTFDIPLATDDRL
                     KAEMEAVIDIRERQAKRSQEKAPFTVTTVIRMEKDSPRLQFQTSFNNQMTNHRLRVLF
                     PTHLKTDHHFADSIFETVKRPNHTNAQFWKNPTNPQHQEAFVSLFDGRTGVTVGNYGL
                     NEYEILPDTNTIAITLLRSVGELGDWGYFPTPDAQCLGQQTVSFSFESINATTRFASY
                     WRAQEAQVPVTMAQTKRHSGQLPAQYAYIKGATDHVALTAFKRRLSDNALITRSYNVS
                     NDKACALTLAIPDHTARVTSLLEEDQHEPLPAELGKGEILTLAWKKSESAHL"
     gene            complement(27682..28290)
                     /locus_tag="TV188_000929"
     CDS             complement(27682..28290)
                     /locus_tag="TV188_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1534303.1"
                     /translation="MIEIKQLSKHYGKKTIYDKLSLTFEANRSYALVGPSGSGKTTLL
                     NAIARLEKPDSGQILVNGQDIWSMKEQDYFKDYLGYVFQNYALIEEETVYDNLKMLAP
                     KSNIVEALHSVGLDSSFLSQNIYELSGGQAQRVAIARLLLKKACIILADEPTGALDKE
                     TGDEIIELLLSLVSPDTVLIFATHDPNVFSRVDDIIDICHLQ"
     gene            complement(28287..30290)
                     /locus_tag="TV188_000930"
     CDS             complement(28287..30290)
                     /locus_tag="TV188_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1534304.1"
                     /translation="MRWRATVICIFVLLLTCLSFGAVKEYGNDIKYPVQAAFSLVASN
                     KDVDKGHVLDRIEALAEQEHIQIYRPYLDHTGKEATYLFGTNGKKTVYSSNRKELLTN
                     DLSGMYYTTRSLPSSFETAMTERGLTYKGADLPWYLLPYYFLFTNLRSLAIWTLFFVF
                     ALLLFAVKLMYAKKSMILRSLGLFEHYSRKELLQDLLLMGASFAVSILLFILYQGSIS
                     NVFVKSFTLLILTNAVILLLLMLAVHALFFINIRSLKALAILKNKQATPLVLFVWLVG
                     ICLSSVIFGLSLHKSLETIGKSANDIQVLGKWDKAKDFAEITWLDTLSTHTDDNHQID
                     SDYFKEENQRYQHFLLSFSDNDVIYSALSSLNETNLQSAPDDFKKELKTNGVDPRIAS
                     KVRYVNQGFMLKNKDIFPNNDYGRPAADAVGVIYISKHMMGDADSILNIVNYEWFQYS
                     SLKANQLVVQEVPDGQKSFLFNHKQDQQDIFAQQEEVNTILVQLNFSFMTEPSLLTKF
                     GEMAQKSIYRQALIRDRLTQAGLTNFSSLTNVSNHLILERHKILSQLIGSVIALTVLA
                     IAQCFIIYEYIVSLMKQKAKKISVWFLMGQKSLVLIGRLLLPLALCLFLAIGMMGILT
                     GNRLMVLGIGLLYLGEIVCMSFFAYQAILKHRIQIIKGDFDIL"
     gene            complement(30359..30685)
                     /locus_tag="TV188_000931"
                     /pseudo
     CDS             complement(30359..30685)
                     /locus_tag="TV188_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419586.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin, lactococcin 972 family protein"
     gene            complement(31095..31676)
                     /locus_tag="TV188_000932"
     CDS             complement(31095..31676)
                     /locus_tag="TV188_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEL1534305.1"
                     /translation="MRRIRLATLADAKALLDIYRPYVEETAVTFEYTVPSLTEFERRL
                     SDIMVFYPCLVVEEEGGILGYAYASRFHARAAYAWSAEVTIYLAQEARGRGLGSALYH
                     RLEGYLKGMGILNCNACIASTAHATPYLTNSSQVFHEKLGYRLVGRFHQSGYKFNQWF
                     DMIWMEKLLGEHDVRPRPVMSFRDFLCQKHQSE"
     gene            complement(31936..32349)
                     /locus_tag="TV188_000933"
     CDS             complement(31936..32349)
                     /locus_tag="TV188_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1534306.1"
                     /translation="MLNKMKRLHYLMIFRLLTGQLPAISLMAVLLSKDIHRLSLGSLI
                     SFAIFAVSTAASNYYFSREIAIEQLKEQTRPNLLLTQILFIVVFMIIGIVSIYCGLSS
                     SEFYKQVIAVICSFISFVTMGLMIWGIRYAKAYRR"
BASE COUNT         9571 a         7673 c         6668 g         8836 t
ORIGIN      
        1 cgatataggt aaaccttttc tttttgtatt tgaaaagcta aactctccca caataaaagc
       61 tataactagc ctcatcatga tactcaatca tcagcacttc cccaccatgc ttgcctattc
      121 cagctaataa gcattctcaa cagctctaat agccataaaa tctctacctt agagggctag
      181 gattctcaaa agcttctcct ttgtcaacga gctggtcact ctctttatta gcttgaaatt
      241 taagcttgat tatggtatga tttcccaagc tatgaatagt tctgtcatgc cttattcaca
      301 gtattatcta agacagagct gtcatcttac ctttggggaa tcattctctc aatatcatat
      361 taggaaagag tataaatggg aaacgatata atagctgatt ttttaaacaa gggctgtcaa
      421 aagagtaact ttattgttgg tccctgtgcc attgaatctt atcagcaaat cagacaggca
      481 gcagcaagtg ccaaggcttt aggctacagg tattttcgag ggggagccta taagcctaga
      541 acctcttcta actcctttca gggcttaggg ctgacagggg ttacctatct acatgaggtt
      601 tgccaggaat tttcgctgaa ggctgttagt gagattatgt ctgaaaggca gctagaggaa
      661 gcctatgact atttagatat tattcagatt ggcgctcgaa atatgcaaaa ttttgaactg
      721 ttaaaggtat tgtcaaagat tgacaagcct atcttgttta aacgaggact aatggcaacc
      781 attgaggaat atttgggtgc tttatcttat ttacaagaaa atggcaagca aaatattatt
      841 ttatgcgagc gtggggttcg tggctatgat gtggaaacta gaaatatgct agacatcatg
      901 gcagtcccta ttattcagca aaaggtgaag ctgccaatca ttgttgatgt ctctcactca
      961 acaggaagaa gagatttact attgcctgcg gctaaggccg ctaaggctat cggtgccaat
     1021 ggtattatga tggaggtgca ccctacacct gatcttgcct tgtcagatgc cgcgcagcag
     1081 attgattatc aacagctaga gcagcttgga aaagagcttt gggaaagcta actaacagca
     1141 gccacaggtc cagtcatttg aactaatggt gcttaggaga gaaagacgca tgacacaaac
     1201 acttcaggtt aagtctcgta tcaatgacta tccgattatc tttacagacg atatttttca
     1261 gccgctgaat caatttcttg ctgaaaaagg agacgtcaag ctattattta tcactgatca
     1321 aacggtattt gatttatacc agcctttatt tagacgtttt caacaggatt acgatagtta
     1381 ccttcatatt gctgctccag gggggcaatc taagtctcta gaggaggtta gtcggattta
     1441 cgatcgactg attagggcta atttttctaa aaaggacgtc attgttactg ttggaggagg
     1501 ggtgattgga gatcttgggg gatttgttgc ggcaaccttt taccgcggga tttcctacgt
     1561 tcagattcca acaaccttac ttagtcaggt agacagcagc attggtggta aggttggggt
     1621 tcactttaag ggcttgacca atatgatagg cagtatctac cctccaaacc agattatcgt
     1681 gtcagccaag tttttagaca cgctttctga aagagaattt gcctgcggca tcagcgaaat
     1741 gattaaaatt ggttttattc atgatcgcaa gctctttcaa cagctcctag ccttccccaa
     1801 ggaccgcaat caagagcagc tcaggcaaat gatttttcaa gcgatttgcc ataaaaaaag
     1861 agtggttgaa aaggatgaat ttgaaggcaa tctccgcatg tccttaaatt tcgggcatac
     1921 gctagggcat gcgattgaag ccttatgcca tcacgagctt tacaggcatg gtgaggctat
     1981 tgcgattggc atggtctttg aggccaagct ggccgtccag cagcagctat tgagccaaca
     2041 ggatttagag gcattacagg ctgcctttga ggcttatcag ctacctacca cacttgaggc
     2101 taagtcaatg acagccgaag ccttgatgac tgttttaaaa acagataaga aaaattctgg
     2161 tcagcatatt gtcctcattt tgccaacgac aaaaggctat gtaagctttc ctattgctaa
     2221 gcatgacagt cgcctgctgg attggctaag aagcctgcta gatatcgcct gagaaggctt
     2281 ttctcctgtc ttattagtcg agtgaaaaaa ctgctgcttc tgaaaaacaa aaaggcttca
     2341 aagcctcttg tttactgagt cttttgatga gaaaagacca cttttttcac agtaaggtga
     2401 aaggcctaag cttcattgct ttgtccctag gtgaatgcta aggcataggt ataagaagca
     2461 taggctactc taaacattat attgacatgc agaggtgagc tgtctgcatg acacctaaaa
     2521 agcaccttga gctgaactga tctcccaggc gttagagcct taatctaacc ttttggaggc
     2581 acttcatagc tcttggtgct tttttaatta tccttaaata atcgtaaggc caactctaag
     2641 gcaataaagg caatgttatc cttggcttct aggtctgctt cattggctaa gcttcttgcg
     2701 tcccattcat cagcatctag attatcagcg gaataaaaaa actgaaaatg ctctagctgt
     2761 ctgaaagctg ctagggcagc aatcgcagag cattccatgt caacacaaat agccccttcc
     2821 tgctttcgtt gaatcatctt gtctctggtt tctctataaa tgccatctgt tgtccaggtc
     2881 ttaccaaggg tataggtctg ggaatgctgt tctaaaacat caatagccct tgttaaataa
     2941 gcttgattca ctgcaatgtc atgactagca ggctgatagt ggtagctggt cccttcgtct
     3001 cgaatagcac tagttggaat aataatagag ttttcactga tagtagcgtc taagactcca
     3061 caggtcccaa aaaccaagag ctgcttcatt cccatagcaa tgatatcctc taaaacccca
     3121 acgcagccag ctgctccaac gtaggaattg aaaaagccaa gcttatgccc tttaacatct
     3181 aattcgtata ttggaatatc aagattagca acgcttgttg tggctatcag tcgatgtggc
     3241 agtgcattaa gtaccctatt aaaggttgct cttgcaaagc aggtgactac tgttttagga
     3301 aagtcatcta tttctgctac aaggtcctta gggttaatga tagcttggta gtcagggtca
     3361 aattgtgtca atatcatagg ctgctccttt gcttttggtg ctttttatta taaataaaat
     3421 gccgacaaac ctcaagacca atcaaagagc tgagcaatta accttttttt ctttttccta
     3481 taccggcgtg agcagcaggc gttcattcct tgttctgaca taaaagctct cggatatagg
     3541 ctaccggcat gtcttcacct gtcatcagct taaaggcttc tgctccttgg taaaggagca
     3601 tgcctaggcc attcatcact tttttagccc catgctcacg cgcaaaggct aagagctttg
     3661 tttctgccgg gtgataaaca aggtcaaaaa ccacaagatc tgggcgaata agagctggat
     3721 cagtaatcag gcgatgctcc tcaaaaggct tcatgcctac accagtcgcg tcaatataaa
     3781 tgctagactc tgaaatagac cgcctaaagg ctcgatcatc cgctaaatcc tgaaggcttg
     3841 ccagggctga ggtttgggta ttaattctag caaccagctg cttggcctgc ttaaaggtag
     3901 ctgttttccg attaaatagt cgaatctcct tggcgccatc aagtcccagt tgaacagcaa
     3961 tggctgtgcc tgcaccgcct gcaccggcaa tcgtaatgat ctgatccttt atcgagaccc
     4021 cttcttctgc taaggctcga atagcacctg tgccatcggt gatatgacca acaagatgac
     4081 ctctgccatc tttattaaca accgtattaa cagctccagc taaggctgca gccggtgata
     4141 gctcatcaag caatgggaca atggcctgct tatttggcat ggacacattt gcaccgcaaa
     4201 tacccaaggc acgcatgccc tgaacagcag cagctagctc agcattacca acctcaaagg
     4261 ctaggtaggc ataatccagc cccagcttag cataagctgc attgtgcatt ttcggtgata
     4321 ggctgtgacg tgccggtgct gccagcaaag ctgttaatcg tgtctgacct gataaacgct
     4381 ctagcatcaa atacctcctc ctttacatca tatcaggcga tgcttatttt ttgctaacct
     4441 agcaaagctt gctaggcatt tactgtcatt ataccttatt tttcaaagac tgtctcagct
     4501 caatcctatt gacagtatga gccgataagc ttgaagccta agcctcctca accatgctcc
     4561 aaaggcctag ctgaagccta gctaagtcaa aagcctgtct gatcggctgc tctaatgtta
     4621 ggtccaggct tagcacatca actacttctt ccagcatgat gtagtgacag ggctgttcta
     4681 tctgatcaag cgataggatc agctgttttg atggcgcatt ggtgctgctg cgatagtcca
     4741 aaacaagcct aagcgagctt aagggcttct ttagtcctgt caggctaatg gcaccaatgg
     4801 cctgtatggt atcgtattga tagcggtagc taagctgggt atcactctga aacagccgct
     4861 tctttttagc aactaagcta agctcttgat tgatccttaa tccttttgta tctgacttaa
     4921 ggatagcttc aagctccaaa gcctctccaa aacaaagggt ctgcccacta acccttgact
     4981 cctcagaaaa aactgcctct gttagctgcc aatcaatagg aaaagccttg gtaaataact
     5041 ggccagcagc tgccctaggc tgcagccagt ctggtagaat gatatcattg ccctttagca
     5101 gccttttgat cagtggctga aaggtcagtg gccttgataa tgctgttgta tagctaaaaa
     5161 ccattacaga attatcaggc agataatggc cttgccgctt taagcagcta tcaggattag
     5221 gcattaagct atcaacagct gatcctcttg accttgcata gggcttgcta ggcttatttg
     5281 tctcattagt gataaagctg tatttatcaa gctgataggc taaaagcttc tcattaacgg
     5341 ctgcttcaga aaccgtcaac tgatagctgg cttccacgaa tcctgcggct ctagctgtta
     5401 ttctaagctg acccgcacga ccatcaagag caataatggc taatagcttg ccaccatatg
     5461 ctcggcgtga caaggcagta tagggcctat ggtcacgagg atcgccatta tccagagcaa
     5521 ggcaggctcc aggaccctca acctcaagct taatcacagg attagcactg agcaccaagg
     5581 tctcattagc atctaacaaa gacaattcaa gataaagtag cgcaggctct gcaagcagtt
     5641 taggaggctc aaagcaggac caggaaagct gagcaggctg ctggtagctg ctcacacagg
     5701 aacgaccgct ggtctgtgtg agcacctgtc ccttgtcgtc ataagcaata gctctcaagc
     5761 tgcctgagcg ataaggaagc ttccatgtca ggtaaaggtt ttgatgaggt aattctgctg
     5821 catcgtcacc ctcatatagc tggtagcaat ggcctgctgg tgtttcatgc cttgtcaggg
     5881 tcttgatgcc ataatcaatc tggcccccat gaccatcatc aaaaagtatt ctcacactag
     5941 cagcattact ataaaccaca acctccacca tgccctgatc atctagctga aggtcttttt
     6001 cctgccagct gggcaggata tgaagtgtcg ttttgtcttt tgaccattgg ctttggtaga
     6061 aataatagct atccttagca aatccagcag tatctaaaat accaaagtag gattgcttgg
     6121 gcgacggcca ctgatcagct gcgcctgagt caatcttgtt ccaaggagta ggctccccta
     6181 gataatcaaa gcccgtccaa acacactcac ctgcaacaaa atcccttgtg attgtatcat
     6241 accaagcctc actagctaag gatccccagt caaccgttga ctggtcatag gaggttagct
     6301 catgatcctg actagctcct cccttgagat gatagacccc tctactatta atagcagagg
     6361 ctgtctctga gccataaagc agccaagtcg ggttgtccct atgcaatcga tcataatctc
     6421 tggccttagc atagttaagt ccaatcactc cttgcacgga ctggagctga ttgacctgct
     6481 ctgccaacgc ttttgtttcc tgcgcccaat gaaaatgctt gtccttgagc ttattatccc
     6541 caagggtaat aggtcttgac tgatccagct cagtgatcca ctggcatagc tccttagcaa
     6601 cataagggta gtggctcaca tcagctgaga agccttctaa caattcattg ccgattgacc
     6661 acatcaagac agatggatca tgaagacctg agagaaccat ggcctgtatg ctatattgcg
     6721 cccaggtggt ttctgctgta gtgactccct ttagcctggc tgcattttgg tgtcccactg
     6781 tcttgtgaaa atggcttgaa aaatcatggc tattaccgtt tttagcataa gtccaggtat
     6841 caaaggcttc ctcaatgaga aataacccaa gcctgttagc cagatcctta agccttctgg
     6901 cactagggtt gtgcgtgaca cgaaccgtat ttgctcccat ttcctttagc aaaacaagct
     6961 gcctagctat agcttcctca taagcacatg cccccaggct accctgatca tgatgaagac
     7021 agaccccttg cagcttaaag gctttgccat tcaaaaagaa accacactca gcatcaaaat
     7081 gcagctgtcg aaagcctgtt tcaagtgtca gccgatcaag cactgctccc ttatggtaaa
     7141 gaagcatatc aagctgatag agctggggct gagctggcga ccacagtttg atatgcctaa
     7201 gaggaatggt catcaccagc ctacctgact cctccaagag gtccaaggct accggtttac
     7261 tctcatatac tgtctgtctc tgctggatat ctgccagctg ctcaaacaga ctaaggctaa
     7321 gctgatagcc actcaagggg acctgttggc tgagtccaag ctctatctca agcgcttggc
     7381 tatcagcctc aagcgctgcc tgggataagg ataaacgaag ccgatcctta tcaagatgaa
     7441 ccttcggaag aacggtcaaa aaagcctccc gataaagccc acttccagaa taccaacgcg
     7501 agctaggcac cagatgttca acccgaaccg ctaatagatt ctcttgccca gggattacaa
     7561 aggctgagag atcatagcta aaggcctgat agccattgac atgctctcct atcaaatgcc
     7621 cattaaggta tacctgcgtt tccatataag ccccatcaaa ggtcacatag accttatggt
     7681 cagccagctt tggatcaagg gcaaaatact tccggtacca gcctacacca cctagcttat
     7741 aggcactttg agcttcgcca ttaaccgtat agggctgatt aatgctaaaa tcatgtggta
     7801 aagctatctg ctgccagtcc gaatcatcaa aaaatggctc ctgagcgagc tgcaaatcag
     7861 ccatcagaaa gcgccacccc tttgaaaagg catggcagcg ccctacttta tcaatccagt
     7921 gaagctgata gatatcccca tgagattgat ccgttgaacc agtgattgtc tctacagaca
     7981 tagcgccccc tttcttaata gcttcctttt atagcttgat aattatcttt ataacggtct
     8041 ctaaactcct tgggcgataa accatttaat tttttgaaca tttttatgaa ataatggtta
     8101 gtattatagc ctgtctcata ggcaatttcg ttaatcgatt tattggtgta aagcagcaat
     8161 tgctgtgcct tttggatcct cacctgattg aggtattggg aaaaactaca ctctgtttca
     8221 tttttaaagc gttgtcccaa ataaacccca ttgatatgca agcgatctga cacagccttg
     8281 agggttaatt cctgagagta ttcctcctga atacaggtaa tggcttcact gaccagatca
     8341 gaatagcgct tttggggctg attgcttttg cttgtcagct caagcacctt ttttaaggct
     8401 gataagatct gatcaatgga ctgactatcg tgaatagtct tgaccatcga taggtaggtc
     8461 gttcgatcta aaatcggaaa ttggcgataa atgtctgaaa ataagagaaa agagacgtgc
     8521 ttgacgtcct caggagagaa gcttagctct gtcatctcct caaagattgc ctgtaatttg
     8581 gagacaatag ttggctcgtc cccaatcatc aaggtcttgt taaaggaaaa aaactgcaat
     8641 cgcgattccg gcagctcaat tttagcgttg gtcttagcag ctacctgaga cacctcgctg
     8701 ttgtaaaaaa agctccttct gacctgatta tagctttcat acacattttc ccaatcaaca
     8761 accgtttctc ctagaatgat ctgattgatg gtattgtaaa atcgctcctg aagcgtatta
     8821 gtaaagcgct tagcctgatg gctctgtcct aatagaatga ctagatagac cttcttttgc
     8881 tctgcctttt ttaagtaaaa gggctgcttg gaggcctcaa aaaaggcttc taaggcaggg
     8941 ctaaaagtct tgcaatccac atacaacacc gtaaagccta aaagctcagc ctcgggttgc
     9001 tcctgcgtta gttgaaaaaa ctctttctca ctcaattcat cagcaagcca gagatttatc
     9061 aagccctcac gataagcagc ctgacgcaaa gaagctgccc tctgctcatc aagccattcc
     9121 ttaaaataga gcattttagc taccagctct tttttatcaa ctggctttag gaggtagccc
     9181 ttagtctcta gctccatagc cctttgcaca taggaaaatt cctgatagcc tgataaaatc
     9241 aaggtctgca aatgcggcaa tacatctctt gctgcctcaa tcaattccag gcctgtcata
     9301 ccaggcatat tgacatctga aatcatgaca tctacagcgc agtcatctag gtaagctaag
     9361 gcttctttgg ctgaccttgc cgttgccaca acctcaaagc caagcgcctg ccagtcaata
     9421 atcaccttta ggccctgtaa aatcatgtat tcgtcatcaa ctaataagac cttgtacatt
     9481 aagcttcctt tctaattctg atctgaatcc taaagccacc agtcggtgcc tgagacatgg
     9541 accaagtcac tctgtctcga tatttgtgaa ataggcgcat atagacattt tgcagcccaa
     9601 tagagctatt ccccgtcgat tgcggctcct ctaagccctt ttcaatagcc actaagcgct
     9661 cagggctaat acccttgcca ttatcaagca cctgaatcaa aatactgtcc tcctcatcta
     9721 gcgccttgat gctaagggcg ttatcatagc ggctgtaatc aatcccatgc acaaaataat
     9781 tttccaccaa gggctgaatg ataaacttag gaatttccac atcagccacg acaggatcaa
     9841 gcttgacatg gtaggcaaag ctatctggat agcgcatttg atacagatag atgtactttt
     9901 cacaaaaagc cagctcttct tttagagtgg ttaccttatc ctggctgatg ttatttcgaa
     9961 gtaaagcggc aaaggcataa atcacatctg ccaattcctc ctgctgacag ctaagcgcat
    10021 acatgcgaat atattctagg gtgttataca aaaaatgagg attgatttgt gatgacaagg
    10081 cacgcatctg ggcatctctt tgctcaacct caaggacata gatttctaaa atgtaggcat
    10141 tgatgttgcc aagcatttga ttgatcgcct cagaaatgtg atacagctct aattccatat
    10201 gactgttgtc aatccttaac gacaaatcac cagctgcaac catttcaata gtatctgtaa
    10261 tctcagagac ctgtcggata taattgcgaa ataccctgaa aaggagctgt agcaataacc
    10321 aagctagcaa taacgagcca aggccataca ggagcattgt acgcacagcc tcttccataa
    10381 aataagacct tttgaccgcc acataggcca gcaagtctcc cgagcgattg tactgaatat
    10441 gatagctctt gctgagagct gtcaaatcaa tagcctgatc cgcctttagc gcctttttaa
    10501 gacctgcttc aagctccgga aaggcagcgc ctccctgatg aaagagctct ctgccatagt
    10561 aatcaaaggc aaaggtcgct agatacttat gctgctcagg ctgtagcatc gtgctggggc
    10621 ttgcaaagtg cagatagagg cggcctgtaa catcacctga ctcagggtgg cgaatggacc
    10681 ttactaagta attgcccttt agcgtctgag gcttaccaaa taagagccgg ccggtcttaa
    10741 tcgacctatc tgcatacaaa taggacgtgc tatcgtccag catcagggtc agcccatcta
    10801 aatctggata caaatcaaaa agccttctga cctgctctga aaacagaggt gtgtttttgc
    10861 cctcacccca atcctcaaaa accttagtaa gatattgatt aggggtcaat atcatgtact
    10921 gatacagatt tcgataatcc tctggacgcc cgatcagctg ctccagcacg cgcagggtaa
    10981 tatagttttg agattgtagc cttgctaggg tctcatctag ccgcatttgc atttgattgt
    11041 caaccatttg gtaggtattt cgaatcgaat aggtgcttag accaaccgca cttaagctaa
    11101 agagagccac gataaacagg ctatatattt tcatcaagcg gttaattaaa aagccctgct
    11161 taatatgctc catcaagaac cgctttaaag atttacttgt catcaatgac tccatctacc
    11221 atgcgacgat taggcttggt gaccatatcc agcaacaaaa ccagcgcacc aaagctcaga
    11281 aaaagataca agcccttata ctgccaagta aaccaagcaa ctccagctaa aaccacaagg
    11341 gtcaacaaaa actgcctggc attcaagaaa atactgataa aagacagctt gagattctcc
    11401 caaaaagcaa tttcataggt cactgcataa aaggtcatgt aaatcacaat catcaccagc
    11461 caaaccatga caaacatgat aataaaggat aggctaaacc acagcagcga ttgaaattga
    11521 atggccaagt acaggctcgt attcagcaat aatagcaata atccaaagaa gaaaaagctg
    11581 agattggcct ctttgaagac ccgacgccat atctgaaagg cccgcttgag cgaataatgt
    11641 ttctcctgct gactggtctc caaaaacaag gtaacaatgg tctgccaagc tggccccact
    11701 ccaaaaatca cagcaccaca taaggaaagc aaatgaaata taagggttag ctgcatcatt
    11761 ttccagatga gaaagcaggc tttttcaatt cctgtcataa gattatcctt ttctagtatc
    11821 ctttgtagga ccaatagcgc cctaagagaa gcaacgatcc ctcagccaga tgactaaggt
    11881 cttagctgtc atgatgataa gatgagatac ttctaatata gcatatttta ctctaattgt
    11941 gacaaaagct taataaaaag aggacagccg actaaggctg gtaaaacctt gtcagcaagg
    12001 gctttggtgg accaactgcc ttgcaagcag gctctggctt ttttctaaga gaggccttat
    12061 ctgtcagctc ttgtatgcct gcttgagcta aaaagaactg aggctgtccc cagttcttac
    12121 caccttgcaa ggaaagtcca ttgccttatt tattttttgt aacaaagtcg tccaattgct
    12181 tttgcacttc cttttgaacc ttgtcccaac cagcgtcctt aaggtctgaa agaagttttg
    12241 gaagagcttc atcagggtct actgtaccag tattgatact agctttataa cggttcatca
    12301 cgtttgagat ttttgatagc tccgttttga ttgccttggt atctaccgta aagcctagga
    12361 tcggagactc tttagcgtct ttgattgatt ggtcacgctt tgcaatcata tcatctgtga
    12421 tcgattcttg ggtgtagagg atcttgttgt taccagtgtt ccaagcaccc atgtgcattt
    12481 tgggttggta gccatcaagc agcttgattt tcttgtcgcc aaccttttcc caggccttgc
    12541 cttcaacacc ataaacaaga ccatttagca attctgggtc gctgttaaga agggaaagaa
    12601 cttcaacggc cttttcttta tttttagaca catttgacac gacaaagtta gccatttggg
    12661 cttgtgaggt cgttttaaga ggctttgtca atggtcgtga cacaatgtct ttaccagcag
    12721 cattggtcaa gatggtatcg ccatagtcca taggaccttg ggtttcttca cgcatgaacc
    12781 aggtattgcc ttcaagcggg tagccttctg tgttggttgc tgcatctgtt ggaatcaagc
    12841 cttccttata ccatttatgc atcaagcgta ggtttgcttt aaagggctca tcttcgtact
    12901 gattaatgat ggttggtttg ccttcatcga ttttaacagc aaatggttga tttttggtca
    12961 atgggtaatc gtagtcacct gacatgctaa agacttgacc aatcgcaaag gcagcagtat
    13021 taggttcttt ttcgtggaat tgtttcaaga ccttttcagc atctgcatag gaattgatgt
    13081 ttgaaatgtc aaggccatat ttgtctacca attctttgtt gaaagacagc atttgctgag
    13141 catagacgtt agcatctact ggaaaggcat aaagcttacc gtcaatggta tttcctttaa
    13201 tgtaggccgg atctaggttc ttataggttt tcttggcgta ttttggcatt agcttagtca
    13261 aatcagcaaa ggcacccttt tgagcattga ccacataatt gttggcaaag gcaatgtcgt
    13321 aattttcacc tgacgcaata atgatcctca tcttgtcgtc ccaatcaccc cagccaatgt
    13381 attgcaaatc aagggttgcc cctgtttttt ccttaatacg tttatttgca attgtcatca
    13441 gctcatcaaa gttatcaggc ttatctccca cctgatacat caatagcttc acctcaccgt
    13501 ccttagaagc tgatttgctt ccacaggctg tcaagctagc agctgcaagc acagctcccg
    13561 tcacacataa gattgtttgc cactttttca tcagtaagcc tcctaaaata atttcttttt
    13621 ttgataacag aatcattgga acggtcagct gtatgaccta ttccaaatgg gtgattattc
    13681 cttaaccccg ccgatggtta gtcctccaac aaagtatttt tgaaagaaag gataggttag
    13741 ggcgatcggc aaagttgcaa tgacaacaat agccatgcgg acagattcct ttggtaaaga
    13801 ggctaagcta tcagatagct gggcgctcat gccagcattt tgggctagtg cctgtatatt
    13861 gctttgaatc ttcatcaaga ggtattgcat cgggtaaagg ctctcgcttt gcacatagag
    13921 cagcgcattg aaccaatcat tccaataggt taaggctgag aacaggctaa tggttgcaat
    13981 cccaggaact gccaaaggta aaacgatttt cataaaaatc atcaattcac ctgcgccgtc
    14041 catacgagcg gattcaataa tactatcagg aacggtcttt ttaaagaagg tcctcatcac
    14101 caaaatgcca aagggtccca gagccatcgg taaaatcaag gcccaaaccg tatcctttaa
    14161 ttgcagcagg ttactcacca ccaaataatt ggctaccata cccggtgcaa aaagcatggt
    14221 gatcaaggca tagatggtaa aaaaacgcct gtagggaaaa taaggtcttg agatggcata
    14281 agcataggtt gaggtcattg tggtattgat aaaggttcct aaaacggtga taaatacaga
    14341 caccgcaaac gatcttatga tccgatgaga catagcccct tggaaaatat aatgataagc
    14401 ctttgtcgac caagcagctg ggaaaaagct atagccatga ttgatcagat agctttcatc
    14461 tgtgaaggaa ataatcatca caaagataaa aggaatgata caagagatgg caaaaagagc
    14521 gattaacaca ttaaagacag cattggtttt tgggtcaaag gttctgacgt tgaccctttt
    14581 aacagttttc tttttctcca tgtcctcctc ctaaaataag gctgcatcgg gatccatacg
    14641 acgaacaaaa gcattggtga tgagcaggat acaggttccg accacagatt gataaagact
    14701 ggccgcagaa gccatactaa tatcaccagt agctgtcagg gcattgtaga cataggtatc
    14761 taaaacactg gtaacatcgt aaagaggacc tgaattttta ggaatcacat aaaacaagcc
    14821 aaagtcagat ttgaagatac tcccaatatt aataatcaat aggatagaca tcatcggcaa
    14881 aagctgtgga atggtgatat gtctaatttg ctgccactta ctggcaccat caaccatagc
    14941 cgcctcatag taggtgtctg atattccctt aaccgatgcg taataaatga tactgttgta
    15001 gccaagtcct ttccaaacac tcatgaaaag taaaatcaag ggccaccagg tgggattgga
    15061 ataccatttg attgggctat tgccgctatc aatgagcagc tgattaataa agcccttatc
    15121 cgtatttaaa aaggcagaaa caaaatactc aatcacaacc catgataaga aataaggcag
    15181 taaggacatg gtatgataga ccttaacagc cttcttgttt cgaagctcac tcatgataat
    15241 agcgaaagcg atggcaaaaa agacgttaaa tagtaaaaaa ataagattat aagcaatggt
    15301 atttcgcgta atcaaccaag catccttaga ggcaaaaagg tatttaaagt tatctaagcc
    15361 aacccaggga ctttctttca ggctttccat aaaacctcct gctgagtaat gaaaatcctt
    15421 aaaagccact acattagcta atactggaat gtaaaagaaa aagatgaacc agacaaatcc
    15481 cggtaatacc atcagcaaca aagcgcggta tttgatcaca tttttccaaa aggatttctt
    15541 gctgctgatc tttgtcgtca tcttcccaac ctccctttgc ttttcaattg atgcttcaag
    15601 tatatcaagc gcttacacat agaacaagca acaaattata ggtttgataa cacaaattat
    15661 aggtatcata gcacaaaata taggaatgcc gagaaagtct tttcaagcac ttcaaaatct
    15721 gtcatactaa gggtagctaa ttggtaatat acctgttata ggaggaatta caatgacctt
    15781 attatgtatc gacataggcg gcaccagcat caaatttgct atttgtcaca agggcaggct
    15841 aaaaaagcaa agcagtcgcc caactcccca aagcctagag gacttttacc atatgcttga
    15901 cgagcgactg gcttactacc gcacagaaaa gctctcagga attgccatta gctcccctgg
    15961 agctgtcaat aaagcaacag gtatcatcga gggagcaagt gcactgcctt atattcatgg
    16021 ctttcccatt cagcaatgcc ttgaggagcg actaggtctg ccggtttcga ttgaaaatga
    16081 tgccaactgt gctgctcttg ccgaatctgc tctaggtgca ggacaaggca ctagcagcct
    16141 tgccatgctg gtacttggca ccggtgttgg aggtagccta gtgattaatg gcaggattca
    16201 ttacggtgcc catttatttg gaggtgagtt tggctttatg gtcatgaatg agcgttatca
    16261 aaccttcagc gaattaggca ctgtggtcaa tatggccaag cgctatagtc agatcataaa
    16321 tgatggtaaa agttacaccg gtaaagaggt cttagagcta gctgatcaag gagatcctgt
    16381 ggccctaaag gaaagacagg tctttcttca aagtctggca atgggggtgt ttaatatcca
    16441 gcatgccttt gatcctgaaa tgatcctaat tggtggcggt gtctctcagg ctgactttct
    16501 tcttcctgcc cttgaggctg aactggataa gctctatcag atagtcagca tttctgattt
    16561 gagaccgcag cttgctatct gccactttaa aaacgaggcc aacctactag gtgcctctat
    16621 tgattttatg caagagcata gaaaggacga gatgtggatc gattagactt cattgacacc
    16681 cgctttggaa caaccaatca ctaccatttt tcacagggaa attgcctgcc attgacaggg
    16741 gttccctttg gcatgcatta tctaagcgtc gaaaccagtc aagatcgagg ggcttggtgg
    16801 tttcaccccg atgatcacag cttttcaggt attcgcttga cacatcaacc cagcccttgg
    16861 gtcggtgatt ttgcgacggt tacttttctt ccagtcagcg gaccgctgac caagggagat
    16921 gtgtttcata atcagacctc ctatcgtccc aaggaggcag cttttcggcc tcatcttctt
    16981 gagattttta gccagagaca tcggattttg acgcgagcaa cagcagctgc ctacagcttt
    17041 cattgtgatt tttcctttga taatggcaaa gcaggcttga ttatccataa ccccggaaaa
    17101 agctcctggc aggtgacagc tgatggtaaa acaatccttg gctgtgtgca aaacatcaca
    17161 gactgtcagg ataaagacct agccatgttt gtttatcttc agtttagcag ccctgtgcta
    17221 aaaaagctta tcggagaaga cttaaactcc aaatctcttg atgattgcag caagacgtcc
    17281 tttacctatc tccaatttgc tgatgacctc aaacatcttg agcttagggc ggctgcttct
    17341 tttattagct ttgatcaagc tcagctcaat tggcagaggg atttccccag atcatttgaa
    17401 aaaagccttg aatacagccg caaggagtgg ctcagctacc tcagtcgtat tgacattaag
    17461 gataaagact ttgataaggt caaggcctac taccagcatt tttaccgagc cctgctattt
    17521 ccccaaagat ggtatgaaat cactgcaacc gggcaggcga ttcactataa tacaacaagt
    17581 caaagacctg ttgctggaaa atactatacc aacaatggct tttgggatac ttataaatct
    17641 gtctatcctt tgctgtctct aattgcacct gagatttatg ctgatatttt agagggactc
    17701 ttgtcagctt atcaggacac caactatctg ccaaaatggc tgtctccaga tgagcgaggc
    17761 ctgatgcctg gaaccttggt tgatgctgtt attgctgatg gagctgtcaa aggcatcaga
    17821 aaagacctga tgcctgagct tttagaggct atgctggcaa ctgccaatac agacagtcaa
    17881 ggaacaggct atggccgcaa gggcaatcaa gactatcaag agctaggcta tctgccaaat
    17941 agctaccagg aaagcgtcaa tcagactcaa gattatgctt atagtgattt ttgtatcggc
    18001 caggtagctg cccttctggg caagacagca cttagtgacc aataccacac gcgatcactc
    18061 aattaccgcc atttggtcga tactgatacc ggctacctca aaagcaagga tcgacaaggg
    18121 caatggcaat gtggctttaa ccctatccac tgggggcagg actacaccga gggctcctat
    18181 tatcaaaatg gatttgcctt ttatcatgat attctaggtt acattcgact gatcggagga
    18241 aacgccgcca ttgccaaaag acttgaggag ctgtgcaatc atgagcctgt gtttgacgtt
    18301 cacagctatg gctttgaaat ccacgaaatg agtgagctag ccgcacagga ttttggtcag
    18361 attgctatct caaatcagcc aagctttcac ctcccctatc tctatcacta tatcggtcag
    18421 ccacaataca gtcagctaat ccttaaaaat ctgctcagtc atgcctttac cgatacaggc
    18481 tacccaggag atgaggacaa tggcagtatg agcgcgtggt acctgttaaa cagccttggc
    18541 ctttaccctg ttacaccagg aactgggcaa tacctgattg gtattccaac tgtagatcag
    18601 gcaacccttt atctgccaaa tggcaatact atccaaatca gctgtagggg caatgtccct
    18661 caataccaat ttgtcaaaga ggtcaagctc aatcaggcta gctacaacaa gctctacatc
    18721 aatcatgatg atctgattca gggctgtcag ctcgactttc agctgggact agttccccca
    18781 ctcaagcact attcggctga ggacctgccc tactccctaa cccgttaaaa gctaaaaaaa
    18841 gcatgtcatc actcgtacta cagcaagcca tgacatgctt ttagttatgt gactttagtc
    18901 cgtttcgctc cgtaggtacg aaacaataaa tcacccgtta gacggatagt tatgatgtta
    18961 ggaaatcctc ttttacattc cttaatcgct atcactggca tagctcatca gcaagccctt
    19021 atgctaaccc atcaccctag caggtaaaac cgctaaagct actagctgct cctgtaaaat
    19081 ctctcttagc ttctctaaac ctagctttaa aggagattgg gctggctttt gtgtttttct
    19141 tcttttctta gctaattcca tttgcctctg ccacctcctt aaaccaatac cctgattttt
    19201 tcacacgccg acgctgagtg cggtgattat tttctaccag accataacgg tttttatagg
    19261 catttagcca agaccagcaa ttaataggtg tccaaacatg atagccaaag caattagagc
    19321 ccgcttgaat ccccttatga agataggtca ggtgctcttt taaaaactga atgcgatagt
    19381 cgtcttgaat ctgtccgctc tcatctcggt aacgatcctc tcctgaaatc ccaaccccat
    19441 tttcagataa aaaccaaggg atattcctat actgatcacg catttttaga gcaatatcat
    19501 agaccgcctc tggataaatc tcccagccct tgtccacatt catacgacgc tgcggcatca
    19561 gataggcatc ataataccac tcaggactcc aggaagggct aatcacagga ataacctctg
    19621 gcgccttcac gcgcttaggg cggtaaaaat taatgcccac gtaatcaacc gtataagcag
    19681 ccataagatc cagctcctct ggtgtggact gccagagcac tccatctctt tgtagtattg
    19741 ctaccagctc ctttggaaag ctaccgtaaa cagcagcaga cataaagagg tcattgtgcc
    19801 acagctctgc aacatgagca gcagcaagat cagcctctga atcagttgcc ggatagatcg
    19861 gtgtcagatt gagaatggta ccaacactgc cattgctcag ctctgctgct tgttcttggt
    19921 aggtacagat aaccttagcc gttgcaagtg ctagattata agccacctgt accgcttttt
    19981 tcccatcaac aatggcaggg tagtggaatt gcagcaggta tgagccctcc accacaacca
    20041 tgggctcatt gtgtacaaac caatccttaa cgcgatcgcc aaactgctca aagcatactc
    20101 tagcaaaggc aacaaacaaa tccacaacat gctttgattc ccaaccgcca tatttctgat
    20161 aaagagcaat tggcaaatca aaatggtgca aattgatcac cggacgcata ccatgtgcta
    20221 ggcaggcatc aatcaccctg ttatagtaag ccagtccatc gggattgatc gtggctgtct
    20281 caaaatcatc aattaagcgt gtccactgga tagaggtccg ataggaattg tgacccaaag
    20341 acgctaataa agctaggtct tgatcatact gatgaaaaaa atcagaagcc gtatcaggtc
    20401 caacataatc ataaaacagc tcaggatttt gctcatacca ataatcaaat aaattgcgat
    20461 gcggcttttg aaagcagcct tcactttgag ggcctgatgt agcacttccc caccaaaatc
    20521 cttctggaaa ctctagcatg tcccttgttc tcccttataa actaattaag tataatcctc
    20581 agctctagct tcagcgacct gtgcctgatt gcctagcatg ctattctcct gaagatagtg
    20641 caactgataa aagcggcttg gaatattgct tccaattcga tgcctttgct cctgaagctc
    20701 agcatattgc tgctcaagat caggcgcttg ctctaaaata accctccaaa agctctgatc
    20761 agccttagcc cgatcaaacc aaggagcaat agcctgttga aacgcaggaa tatcaagctc
    20821 tttcagctta tccaccagct ctaccagctc agctacccaa ccagataagc tagctatgtc
    20881 cttacgcata agggcctcct ccacctcaaa ggggagatcc ctgtgcaaat gacgattgcc
    20941 attatgccaa gcaaagcgca aaagcgctaa agccatagcc ttatctccag tatagtctct
    21001 caaggcctct agccaagaat agcttggctg ataacgcttg gcgtcccaca ggtagcgact
    21061 catatcaatt aaagtcggct ttgatagttc ccagctaatc attggattag acacaatccc
    21121 cctgacctga tagtctggct gacacaagaa aggagagcga ttggcaaacg gggtcaaaaa
    21181 gagcctctta gaatcgtcct gataatcatt gacagggata ttatcccaga tgattatggg
    21241 ccgccggtag atggctgcta ttgtctcaat atctgcctga gaaatctgac tggccagagt
    21301 gcttgggcca gtccagaaaa aagccacctc agcaggaata gcctctgata actctgctaa
    21361 ataaagagag tcatgatgat tatcatactc tgtcggacag acaaccaagt caggggctgc
    21421 atgctgccgc tgtaaaaact ggtaaacagc tgttgccaaa tgtgcttggg cataggctgt
    21481 ttttttgaaa cgtctctcaa ctgctgccac tatttggtaa tcaatatcat caagcagcag
    21541 gccaaaatga caaacaccca aatccaacaa ttgctgcaat ttttgataga gcagctgata
    21601 gtcctcttcc ttggtgtagt caaaatcaag ccccggacta atcatgtacc aaaagtcaac
    21661 ctgtctttcc ttggcaagct ggatcagatc cctaaaatga gccacccaat cctctggata
    21721 gggctcacgc cagtggctgc gctgatagtc atcattttta ggggcataca tgtaggtatt
    21781 catgccctta tcagcaataa agctcaagca atctaaacgc tcctcacgcg tccaaggggt
    21841 gccataaaag ccttcaatca caccacgcat ggcaaaggac ggactatgcc taaccgaaac
    21901 aatcggcaaa taaagcctgc cctctttaac agtcattacc ttttctaaag cctcctgagc
    21961 atagcgaaag cctcttaaat tttggctttc aatcacaagc tccttatcct ctgaaatggt
    22021 caaggtaaag gcatccctag ctaaggtgcg gttaaaaacg tgcttaaggg tcaagtcagc
    22081 tgctccctcc tcaacccagt tgacatagac tgacgctgta agactaggct tcatagctgt
    22141 ttggttctca aatcggaaaa aacgaccaac aaagcgacag gaaacagggg cgtcaaaaac
    22201 gaggtaatca cctctggtta tcacctcctg atagtccttg agggcttgat aaatagacat
    22261 gacacttctc ctttttatag catttctagg gacttttgac tgctttctct gataaagacc
    22321 ttaacaggaa gctgacaaga cgccgtctgc tgatcaggcc gagtcagccg ctctatcaat
    22381 agttgcgctg cttgctgccc catctggtaa aaatcctgtg cagctgttgt caattgaggg
    22441 ctgattaact gagaggcttg gctgttgtca aagccaacaa cagctacctg atcaggaata
    22501 gatagcccga cctgtagaat tttttggatc aattgaatgg ctagccaatc attttcaacc
    22561 actaaaccag tcttttcagc tgtagcagcc gtcagctcat caaccaatcg ctcaagataa
    22621 gcagcattgc tttctgactt cagcttcaca aaataattgg cctcaagctc tgtttccgcc
    22681 atcgcagcca aataacccaa ataacgatct ctaacagagg aaacctcacc aaaggaagca
    22741 gttgccacaa acatgatccg acggcaatcc tgatcaatca aatgcttggt caactcatag
    22801 gctccgccct tattgtctgc aacaactgct ggaaagtcaa acaggtctaa ggccttatcc
    22861 aaaagcacca gagcaagccc acgctgggca caataaaaga gcagctcaat actatgatta
    22921 acgtcttctg gataataaat cacaccagca taatcagcta gctcctccaa gcttaccgta
    22981 cttgtaagct ggaccatcag gcgatagcct ttgtcagcaa cgaccgtcat gattccttta
    23041 gcataatctc ccaattcgta atcagaagca aagggcagga tcaacaaaat gtccttatta
    23101 ggctgagtag acggtggtgg gccatcggtc acaaagctgc ccttacctct gctgcgtgta
    23161 atcaagccct cttgctccag ctctactaag gctcgcttag aggtaatgcg gctcaccgaa
    23221 aattgctctg atagggcctt ttctgttggt aggcggtcac ctgcctgtaa ttgccctgaa
    23281 tcaatttgtt ccttgataaa atgatatatc tttttatata gtaattcagt cattttttac
    23341 tccctctagc agtatatcac gaaaaaaaag acttgtaaac cttttctaaa gtggtagaca
    23401 aaaataaagt tatatcttat aattaaaaaa gatatcaaat gatatatctt ttaggaggat
    23461 atgatatgac aagacctatt cctagcagtg tgctcaggtt tatggacacg attgaagagc
    23521 tctgcggtga agagcaccgt agctgggcca ttaattttaa agccagcttt gccaacacct
    23581 tggaaacgac cctaaaaatc gacgaagatg ggaccagctt tcttctaacg ggtgatattc
    23641 ctgccatgtg gctgcgtgat tcaactgcgc aactaaagcc ttatctcttt ttagccaaga
    23701 cagatgctgg catgagacaa atcatagcag gtctcgttaa acgtcagttc cgttacattt
    23761 gcattgaccc ctatgccaac gcctttaacg aggaggaaaa tagcaagggc caccaagcag
    23821 accacaccca gatgggacct tggatttggg aacgaaaata tgagattgat tccctctgct
    23881 atccgatcca gttagcctat ctgctctacc gagagacaga ctgtacagag catttcaatg
    23941 aggatttcca cagaggaatc aagctgatcc ttgatgtctg gagcacagag caagaccaca
    24001 ctgcctctcc ttacagcttt gagcgcgaca cctggcgtaa ggaggatacc ttgacccaca
    24061 acggtaaggg agctcctgtt gcctatacag gcatgacttg gtctggcttt agaccaagcg
    24121 atgatgcctg ccaatacggc tacctcgtgc cgtccaacat gtttgctgct gtcgtcttat
    24181 cctatcttga agggctctat actgatctct ttaaggatca aacgattgct aggagagctc
    24241 atgcacttag gcttgccatt caaaaaggga ttgaggagca tgctcttgta accaacagcc
    24301 aaggagagat catctatgcc tatgaggtag atggcctggg gcactatact atcatggacg
    24361 acgctaacat tccaagcctc cttgcggcac cctatcttgg cttttgtgcc aaggacgacc
    24421 ctatttacct agccactcgt caaaccattt taagcccgga aaatccttat tattaccaag
    24481 gcagtgctgc ttctggtatt ggctcctccc acacgccacc aaactatatt tggcatattg
    24541 cacttgccct tcagggctta actgcacttg atcaaaaaga taaagcagat atacttgatt
    24601 tactggtggc tactgacgca ggcacccacc tgatgcatga gggctttgac gtcaatgatc
    24661 cgagtcacta tacacgtgaa tggttctcat gggcaaacat gatgttttgt gagcttcttc
    24721 ttgattatct gggctttacc attagccctt agaaagtgag tcagtgatga cacctaaaaa
    24781 agtacatatc atttcacaca gccattggga tcgcgaatgg tacatggctt atgagcagca
    24841 ccacatgcgc ttgatccagt taattgacga tttactagac ctttttaaaa cagaccctga
    24901 ttttcatagc ttccatctag atgggcaaac cattatccta gatgactatt tgcaggtcaa
    24961 gcctgggcgt gaggccgaga ttagacaggc cattcaggct ggtaagctac gtattggccc
    25021 cttttatatc ctacaggacg cctttttgac cagcagtgag tccaatgtcc gaaacatgct
    25081 ggttggcaaa gaggactgtg agcaatgggg ggcaagcgtt ccactgggtt attttccaga
    25141 caccttcgga aatatgggac aaacaccaca gctaatgcga aaagcagggc taaatgccgc
    25201 tgcctttgga cgtggtatca ggcctacagg ctttaacaat caagtggata caagcgaaaa
    25261 atacagctcc caattttctg aaatgatctg gcagggacct gatgatagcc gcattctcgg
    25321 cttattattt gccaattggt acagcaatgg caacgaaatc ccaaccgagg agaaaaaggc
    25381 tcgacaattc tgggatcaaa agctagcaga cgctgagcgc tttgcttcta ccaggcacct
    25441 gctgatgatg aatggggttg atcaccagcc tgttcaacta gacgttacca aggcaattgc
    25501 ccttgcaaat aagctctacc ctgattacga ctttgtccac tcttgctttg aggactattt
    25561 ggctgattta agtcaggagc tgcctgagga gctctcaatt gtgtctggtg agatgaccag
    25621 ccaagaaacg gacggctggt ataccttagc caacactgcc tctgctagaa tttacctcaa
    25681 gcaggctaat accagagtgt ctcgtcagct tgaaaatatc acagagcctc ttgccacgat
    25741 ggcctttgag gtcacaggta cctatcctca cgaccagctg cgctatgctt ggaaaacatt
    25801 gatgcaaaac caccctcatg actccatttg tggctgtagt gttgatagtg tccaccagga
    25861 gatgatgcct cgctttgata aagcctatga ggtggggact tacttagcag agcgttctgc
    25921 caaccaaata gctgaggcta ttgatacctc catgtttcca gaggatagct gtccttttgt
    25981 cctcttcaat acctgcggtc atgagaaaaa aacggtctcc gacctcaccc tgacatggaa
    26041 gatttttcca tttgggcaac gactgcctaa agctgtttat caagaagcaa aggaatacct
    26101 agagacaaga cagccacaat ttcaggttat tgacgcagct ggcaggatca tagaggaggc
    26161 tgaaatctta ggcacagaca tcgcctttga ttatgccctg ccagagcgca ccttcagaga
    26221 agcctacttt gccatcaagg tacagctaag gctcccactg actctttctg ctatgtcatg
    26281 gcaatgtctt gcactaaaag agactgatca gccttgccaa gcaactgaca ctgacaaaat
    26341 gctctttcat caggacagga gctgtcttga aaatgatttc ctaaaagtca tcatcgcagc
    26401 aaatggcctt ctaacgattg aagacaagct aaatggcaat aggtttgaca gctgtctcca
    26461 atacgaggat tgtggtgata ttggtaacga atatatcttt cgccagccag atcatgatag
    26521 cccctacctt gctcatcaag ggagctgtaa gttgcgggtc ttgaccaaca cagcctatct
    26581 tgctgaaatc gaattgacac agacctttga tattccctta gctacagatg atcgtctaaa
    26641 ggctgaaatg gaggctgtca ttgacattag agagcgtcag gccaaacgct cacaggaaaa
    26701 agcgcccttt acagtaacaa cagttattcg tatggaaaaa gacagcccac gcctacaatt
    26761 tcagaccagc tttaacaatc aaatgacaaa ccaccgcttg cgcgtgctat ttccaaccca
    26821 tttaaagaca gaccaccatt ttgcagatag tatttttgaa accgtaaagc ggcctaatca
    26881 taccaatgcc caattctgga aaaacccaac caatcctcag catcaggagg cctttgtcag
    26941 cctttttgat ggtaggactg gtgtcactgt aggcaattac ggcctcaatg aatacgaaat
    27001 cctaccagat accaatacca tcgctatcac gctcctacga agcgtcggtg agcttggaga
    27061 ttggggctac ttcccaaccc ctgatgctca atgcctcggt caacagactg tcagctttag
    27121 ctttgaaagc attaacgcta ccacacgctt tgccagctat tggcgagctc aggaggctca
    27181 ggtaccagtc accatggcgc aaaccaagag gcattctggc cagctgccag ctcaatatgc
    27241 ttacatcaaa ggagcaactg atcacgttgc tctcacagcc ttcaagcgtc gcctatccga
    27301 taatgcccta atcacgcgca gctataatgt atcaaatgac aaggcctgcg ctcttaccct
    27361 agcaatccca gaccacacag caagggttac cagcctacta gaagaggatc agcatgaacc
    27421 cctaccagct gagcttggca agggcgaaat cctaacccta gcttggaaaa agagtgaatc
    27481 agctcatcta taaccagatt accactacct tgacctaaat cacaaaaaag tccttagcat
    27541 taacgctaag gactttcagc attgtctatt cgaaaaatct atagaagaat agcaatctct
    27601 tcctgacaca aaggaataac agcattgtca agctaattgc tgtagctcga cagtccagac
    27661 taaatgtctc agagcttgcc tctattgtag atgacagatg tcgatgatgt catcaacgcg
    27721 gctaaacaca tttgggtcat gagtggcaaa aatcagaaca gtatcagggc tcaccaaact
    27781 aagcaacagc tcaataatct catcacctgt ttccttgtcc aaggcacccg ttggctcatc
    27841 tgccaaaata atgcaagcct tttttaacaa taggcgtgca atagcaacac gctgagcctg
    27901 accacctgat aattcataaa tgttctgtga gagaaaacta ctgtctaagc caacgctatg
    27961 caaggcttcc acaatgttag atttaggagc cagcatttta agattgtcat agactgtttc
    28021 ttcctctatc agtgcataat tttgaaaaac atagcccaaa taatccttaa aataatcttg
    28081 ctctttcatg ctccaaatgt cttgaccatt tactaaaatc tgaccactat ctggcttttc
    28141 aaggcgagca atagcattta atagggtggt cttgcctgat cctgaaggac ctacaagtgc
    28201 ataagaacga ttggcctcaa aagtcaagct aagcttgtca taaattgtct tttttccata
    28261 atgtttggaa agctgtttta tctcaatcat aatatgtcaa aatctccttt gatgatttga
    28321 atccgatgct tcaaaatagc ctgataagca aaaaaggaca tacaaacgat ttctcctaaa
    28381 taaagcaggc caatgcctag taccatgagc ctatttccag taaggattcc catcattcct
    28441 atggcaagaa acaaacacaa agctaagggc aataacaatc taccaatcaa aacaaggctt
    28501 ttttgcccca tcaagaacca gacggaaatc tttttggcct tttgtttcat cagagaaaca
    28561 atgtattcat aaatgataaa gcactgggca atggcaagga ccgttaaggc aataacactt
    28621 ccgatgagct ggcttaggat tttatggcgc tctaaaatca aatgattgga aacattggtc
    28681 aaactagaga aattcgtcaa gcctgcttgt gttaatcgat cacgaataag cgcctgacga
    28741 tagatagatt tttgagccat ttctccaaac ttcgtcaata atgatggctc cgtcatgaac
    28801 gaaaagttta actgcactaa tatagtattc acttcttctt gctgagcaaa aatgtcttgt
    28861 tggtcttgct tatgattaaa cagaaagctc ttttgtccgt caggaacctc ttgaacaacc
    28921 aattgattag cctttaggct gctatattga aaccattcat aattgacaat gtttaaaatg
    28981 ctgtcagcat ctcccatcat atgtttagaa atataaatga ctcctacagc atcagctgct
    29041 ggccttccgt aatcattgtt agggaaaatg tctttatttt ttagcataaa tccctgattg
    29101 acataacgga cttttgacgc aatccttgga tcaaccccat tggtctttaa ctcttttttg
    29161 aagtcatcag gagctgattg taaattggtt tcgttaaggc ttgaaagtgc tgaataaata
    29221 acgtcattat cagaaaaaga caggagaaaa tgttgatagc gctgattttc ttccttgaaa
    29281 taatcactat caatttggtg attgtcatca gtatgcgtac tcaaggtatc tagccatgtt
    29341 atttccgcaa aatccttagc tttatcccat tttcctagaa cttgaatgtc attggcagat
    29401 tttcctatag tctccaagct tttgtgtagg gaaagcccaa aaatgacgct agacaaacaa
    29461 atccccacca accagacaaa gaggaccaaa ggggttgctt gtttattttt tagaatggct
    29521 agcgccttca acgaacggat attgatgaaa aataaagcat gaacagcaag catcagcaat
    29581 aataaaatga cagcattagt caagatcaga agtgtaaatg acttgacaaa aacattggag
    29641 atactgcctt gatagagaat gaagaggaga atactaaccg caaagctagc tcccatcagc
    29701 aacaaatcct gtagcaactc cttgcggcta tagtgttcaa ataagcccag gcttcttagt
    29761 atcatagact ttttagcata catcaattta acagcaaaca agaggagggc aaacacaaaa
    29821 aagagggtcc aaatagctaa ggatcgtaag tttgtgaaca aaaaataata aggcaagaga
    29881 taccaaggta aatcagcacc tttgtaggtc aagccccgtt cagtcatcgc ggtttcaaat
    29941 gatgaaggaa gagacctcgt cgtgtagtac atgccactaa gatcgtttgt caagagctcc
    30001 ttgcgattac tgctatagac agtctttttc ccatttgtcc caaacaggta ggtggcttct
    30061 ttaccagtat gatctaagta gggacgataa atttggatat gttcctgctc ggctaaggct
    30121 tcgatcctgt ctaaaacgtg tcccttatca acatctttgt ttgaagccac taatgaaaat
    30181 gcagcctgaa cagggtattt gatatcattg ccatactcct tgaccgcacc aaatgataaa
    30241 catgtcaaaa gcagaacgaa aatacagata actgtagctc tccacctcat aaaaacctcc
    30301 ttgagaaaag ttgactaaga ggataatatc ttcatccact aaaacgtaca ataaaacatt
    30361 aaacctgata ccagccataa catgactttg cttgaaccca attccactgc ttttttacac
    30421 cggcacgagc ccaaccattg ttttgactat ctttactatt tacatttccc caaaagtctg
    30481 tcacagaagc actacttcct agcccaatag gaactccaag aaaagcgttt gagtaagatc
    30541 agctagcact ggtaattcca aattcccaag tgtccttata ctttggatga gggtgcctag
    30601 tctctgcgtt aacattagat atcccagcaa ctacgaaagc tccaaccaag ccaaggctca
    30661 taaaccattt tacacttctt ttcatgtcgt gtactctcct ttgttaaaat aaagtaaaaa
    30721 aatcttaact agtatcagga tccttttaca acacaagtgt atcatatcat aaaagctttt
    30781 tgggaaagag cttaagtttt tttgcagctc attggcagaa ttgtcaaggg caaaaaaaga
    30841 tattaaaaag accaagctta aaaaataatt tcttttttct catttttaaa gctatgacac
    30901 taggactgct gtagctgacc tagtgacaag ctcagacata accatctcct gctaccacca
    30961 ttttataaca gggcctgaag agttttttta tgattgcggt tatcagtcaa aacttctcgt
    31021 caaacaatac aaaaaaatta gcttcctctg acaggaccta atccttttgt attaatctaa
    31081 gcttttataa ggtgtcattc agactggtgc ttctggcaaa gaaaatccct aaatgacatc
    31141 actgggcgag ggcgtacgtc atgctctccc agcagtttct ccatccaaat catatcaaac
    31201 cactggttaa acttatagcc cgactgatga aatctgccaa ccaaccgata accgagtttt
    31261 tcatggaaga cttgactgct attggtcaga taaggcgtag catgcgctgt actagcgata
    31321 caggcattac aatttaagat tcccatacct ttcagataac cctccaaacg gtgatacaag
    31381 gctgatccca agcctctccc tctagcctcc tgggccagat aaatggtcac ctcagcagac
    31441 caagcatagg ctgcgcgtgc atgaaagcga ctagcatagg cataacctaa aatgcctccc
    31501 tcctcttcca ctactagaca gggataaaag accataatgt cagacagacg tcgctcaaac
    31561 tcggtcaagc taggtacagt gtactcgaag gtaacagcgg tttcctcaac ataaggacgg
    31621 taaatatcaa gtaaagcctt agcatctgct aaggttgcta aacgaatcct acgcattaat
    31681 agccctccta gttttcccag tatactccaa aacaagggcc ttgtcaaaaa cactgatagt
    31741 aaaaaagcct gatccctaaa tgaaataggt tgtcatatcg cttgcagata gacagctcta
    31801 ccccctcaaa agctatttta agcgtttgag cacacaaaca ctaggtatcg tcgctttaag
    31861 gctgatacct agtgctatag cttatgatta actggttaag gaggtgattt caagtaccag
    31921 taccacctca agctattaac gacgataagc ttttgcgtat ctgatccccc aaatcatcaa
    31981 tcccatagtg acaaatgata taaaagagca tatcacagca ataacctgct tataaaactc
    32041 agacgagctt agaccacaat agattgacac aatgcctata atcataaaca ccactataaa
    32101 caggatctga gttaataaca gattgggacg tgtttgttcc ttcaactgct caatcgcaat
    32161 ttctcgtgaa aaatagtaat tagaagcagc agtgcttacc gcaaagatag caaaactaat
    32221 cagtgatccc aaagaaagcc tatgaatgtc ttttgaaaga agaacagcca tcaagctaat
    32281 agctggtagc tgaccagtta atagcctaaa aatcatcaaa taatgtagtc gcttcatttt
    32341 attaagcatt acaacacctt gccctttctt agcaagtcag tgcgccacct attcctccaa
    32401 tagctgcgtc acaaactcta ttaatttttt cagcctcaac ataagcaagt ctaccagtac
    32461 ctaagcatta aatatttcat caatgctgtc gtccacatga atatttccta tgtttagcaa
    32521 ctggcaccag tatagcatat taccagctgc tttcagtatt taagtcttaa aatgtcgtcg
    32581 aaacgtctta aatggtaata cgaaaactgt tgacaccgat taagcgcatt tctaataccc
    32641 gtaaccaata tgagaaagct gtcttaatgc ttcaaagact gagtttcctc tgaggtctct
    32701 ctttagccat catgctcccc tgataacatt tgaaagcact cctttcca
//
LOCUS       DARYYD010000022        32061 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.022, whole genome shotgun sequence.
ACCESSION   DARYYD010000022 DARYYD010000000
VERSION     DARYYD010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32061
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.022"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TV188_000934"
     CDS             complement(126..1544)
                     /gene="sufB"
                     /locus_tag="TV188_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017769002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEL1534307.1"
                     /translation="MSDINETVAPQPIDLGDYQFGFHDDVEPIYSTGKGLNEAVVREL
                     SAAKDEPEWMLEFRLKSLEAFHKMPMQTWGADLSDIDFDEIIYYQKPSDKPARSWDDV
                     PDKIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKAEFEKLGIIFTDTDSALKEY
                     PELFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNEHTGQ
                     FERTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVY
                     NLVTKRARALKDATVEWIDGNLGAKTTMKYPSVYLDGPGARGTMLSIAFANTGQHQDT
                     GAKMVHNAPHTSSSIVSKSIAKSGGKVDYRGQVTFNKLSKKSVSHIECDTILMDDISK
                     SDTIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKE
                     LPMEYAVELNRLIAYEMEGSVG"
     gene            complement(1584..2021)
                     /locus_tag="TV188_000935"
     CDS             complement(1584..2021)
                     /locus_tag="TV188_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEL1534308.1"
                     /translation="MALSKLSSLYMAVVADHSRHPHHHGQLEGVEAVQLHNPTCGDVI
                     SLTIKFADDRIEDIAFAGDGCTISTASSSMMTDAVLGKTKEEALALADIFSNMVQGND
                     DSNQALLGEAELLAGVANFPQRIKCATLAWHALKQAIEKSDEF"
     gene            complement(2008..3234)
                     /locus_tag="TV188_000936"
     CDS             complement(2008..3234)
                     /locus_tag="TV188_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1534309.1"
                     /translation="MFDPNQIKADFKLLDQYVNDEALVYLDNAATTQKPQAVLEAMQA
                     YYQKDNANVHRGVHTLAERATRQYEASRQKVADFIGAKSSKEVIFTRGTTSSLNWVGK
                     FAEQVLKPGDEVLISIMEHHANILPWQQVCQKTGARLVYAYLKKGKLDMNDLQSKLGA
                     STKFVSITHVSNVLGCVNPIQEIARLAHARGAYFVVDAAQSVPHMAIDVQELDCDFLA
                     FSGHKLLGPTGIGVLYGKEALLNQMNPVEFGGEMIDFVYEQEATWKPLPWKLEAGTPH
                     IAGAIGLGAAISYLEAIGMDQVHAHEADLVAYTLPRLQAIAGLTVYGPDRSDERSGVL
                     AFNIDGLHPHDLATALDYEGVAVRAGHHCAQPLHKYLGLHSTVRASFYLYNTREDCDR
                     LIEAILKAKEFFNGTF"
     gene            complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TV188_000937"
     CDS             complement(3261..4523)
                     /gene="sufD"
                     /locus_tag="TV188_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEL1534310.1"
                     /translation="MTKEKILAFSQAHAEPTWLQELRLKAFDVMPHLELPTIERVKFH
                     RWNFGDGSLTESTALGTVPDFMALGDNPKLVQVGTQTVLEQLPMELIEKGVVFTDLAT
                     ALDEIPEQLEAHFGSALAFDEHRLAAYHTAYFNSAAVLYVPDHVEIEQPIEGIFLQDG
                     DSDVPFNKHVLIIAGKESKLTYLERFESIGDKTQAASANISVEVIAQAGSQIKFSAID
                     RLGDQVTAYISRRGRLDHAATIDWALALMNEGNVIADFDSDLIGQGSQADVKVVAASS
                     GRQVQGIDTRVTNYGKHTVGHILQHGVILERGTLTFNAIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENEVTAGHAASIGQVDPEDMYYLMSRGLDQETAERLVIRGF
                     LGAVVAEIPVPSVRQDIVTALDDKLARR"
     gene            complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TV188_000938"
     CDS             complement(4614..5384)
                     /gene="sufC"
                     /locus_tag="TV188_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEL1534311.1"
                     /translation="MSILEINNLHVSIEDKEILKGVNLTLRTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYQVTEGEILLDGVNILELEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAMNAGKEDRDKISVRDFITKLDEKMALLGMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPKFALLDEIDSGLDIDALKVVSKGVNEMRGQAFGAMIITHYQRLLNYITPDLVHV
                     MMDGRIVLSGDAALAIRLEKEGYAGIAEELGIDYKEEV"
     gene            complement(5505..6662)
                     /locus_tag="TV188_000939"
     CDS             complement(5505..6662)
                     /locus_tag="TV188_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HEL1534312.1"
                     /translation="MISFTIDDVLVLIGALLMSLLLTPIVRFLSIRVGVVDTPNARRI
                     NKVPMPTSGGLAIFTSFVIASLVLMPLASNGAHIGGQTYFQYILPVVLGGLVVTITGF
                     IDDVYELSPKLKMLGIVIGAIIVWAFTDFKFDSFKIPFGGPLLAFDPFLTFFLTVLWI
                     ISITNAINLIDGLDGLVSGVSIISLVTMAIVAYFFLPLTNFFLTLTILILIASIAGFF
                     PYNYHPAIIYLGDTGALFIGFMIGVLSLQGLKNATAVAVVTPVIILGVPIMDTIVAII
                     RRSLSGKKFYEPDKMHLHHRLLSMGFTHRGAVLVVYGIAMLFSLISLLLNVSSRIGGV
                     LLILGLLFALEVFIEGIEIWGEKRTPLFNLLKFIGNSDYRQTTLSKWKQRK"
     gene            complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TV188_000940"
     CDS             complement(6669..7433)
                     /gene="mecA"
                     /locus_tag="TV188_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEL1534313.1"
                     /translation="MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAV
                     MDELGLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDLNKDLNFEDLADLGDISQMTPED
                     FFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
                     HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARL
                     IEHASPGTKTRAYLQEHGCQLIFDGAVEELQKIRLG"
     gene            complement(7553..8392)
                     /locus_tag="TV188_000941"
     CDS             complement(7553..8392)
                     /locus_tag="TV188_000941"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEL1534314.1"
                     /translation="MLFIELLKAIFFGVIEGVTEWLPISSTGHLILVQEFIRLHQDKA
                     FMEMFNIVIQLGAIIAVIVIYFERLNPFQPGKSPQQIRLTWQLWLKVAIACIPSIIIA
                     VPLDDWFDAHFNHMLPIAIALIVYGIAFLWIEKRNQTLEPRVVKLSRMSYKTAFFIGC
                     FQVLSIIPGTSRSGATILGAIILGASRTVAADFTFFLAIPTMFGYSGLKALKFFIDGN
                     HLTLSQLLVLLVASLTAFAVSLYVIKLLTDYVKKHDFTVFGRYRIVLGSLLIVYSVFK
                     SLF"
     gene            8708..10276
                     /locus_tag="TV188_000942"
     CDS             8708..10276
                     /locus_tag="TV188_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEL1534315.1"
                     /translation="MKKLVLSCLATLLIFLGGIGTVQADHYLRVGMEAAYSPFNWTQD
                     DSSNGAVPIEGTSQYANGYDVQIAKKIAKALNKDLLVVKTSWTGLIPALTSGKIDLIA
                     AGMSPTAERKKEIAFSNSYYTSEPVIVVASNGKYAKARSIKDFSGAKVTAQQGVWHVN
                     LLPQLEGAKLQTPMGDFSQMRQALTSGVIDGYISERPEAMTAETANKAFKMITLTKGF
                     TVSESDAAIAIGMKKGDDRLTAVNQVLDAISQKERLALMDKMIQQQPSEPKADEAKPS
                     FIKQTWSIFQSNWKQFLRGTGMTLLISMIGTITGLFIGLLIGIYRTAPKAKGKLAALA
                     QRLFGGLLNVYIEVFRGTPMIVQSMVIYYGTAQAFGISIDRTLAAIVIVSINTGAYMS
                     EIVRGGIFAVDKGQFEAATALGFTHGQTMRQIVLPQVVRNILPATGNEFVINIKDTSV
                     LNVISVVELYFSGNTVATQTYQYFQTFTIIAIIYFVLTFTVTRILRYIERRFDADTYT
                     TGANQMQVSEVPNV"
     gene            10269..11009
                     /locus_tag="TV188_000943"
     CDS             10269..11009
                     /locus_tag="TV188_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1534316.1"
                     /translation="MSNPIIEIKNLKKSYGNNEVLKDISLTVNKGEVISIIGSSGSGK
                     STLLRSINLLEEPSAGEILFHGDNVLAEGYNLTHYREKLGMVFQSFNLFENLNVLENA
                     IVAQTTVLKRERSEAEKIAKENLKAVGMTEQYWQAKPKQLSGGQKQRVAIARALSVNP
                     EAMLFDEPTSALDPEMVAEVLKTMQDLAKSGLTMIIVTHEMEFARDVSDRVIFMDKGL
                     IAEEGTPKQLFEQPKQDRTKAFLQRFLS"
     gene            11357..11473
                     /locus_tag="TV188_000944"
     CDS             11357..11473
                     /locus_tag="TV188_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HEL1534317.1"
                     /translation="MAEKTDLASAYRRLKSPNIKTKKRALKIIHEHKRYGKK"
     gene            complement(11997..12887)
                     /locus_tag="TV188_000945"
     CDS             complement(11997..12887)
                     /locus_tag="TV188_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEL1534318.1"
                     /translation="MLEAILIIGFLVIVILSIMASTLYVVRQQSVAIIERFGKYQGTA
                     TSGIHIRLPFGIDRIAARVQLRLLQSEIIVETKTKDNVFVTLNVATQYRVNEQNVIDA
                     YYKLIKPEAQIRSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMSTYGYIIV
                     KTLITKVEPDAEVKQSMNEINAAQRKRVAAQELANADKIKIVTAAEAEAEKDRLHGVG
                     IAQQRKAIVDGLADSIQELKEANISLNEEQIMSILLTNQYLDTLNTFAAKGNQTLFLP
                     NTLNGVDDIRTQVLSALKTR"
     gene            complement(13150..14814)
                     /locus_tag="TV188_000946"
     CDS             complement(13150..14814)
                     /locus_tag="TV188_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEL1534319.1"
                     /translation="MSNITTSLFQEMVQAAATRLGKQAEYVNSLNVFPVPDGDTGTNM
                     SMTMDNGAKEVADKPASTVGEVGQILSKGLLMGARGNSGVITSQLFRGFGQSIKSKEE
                     LTGKDLAQAFQMGVEVAYKAVMKPVEGTILTVSRGAATAALKKADLTDNAIEVMQAAL
                     DGAKGALAKTPDLLPVLKEVGVVDSGGQGLVFIYEGFLSALNGDYVASEDFKATPANM
                     SEMIKAEHHKSVAGHVATEDITYGYCTEIMVALKQGPTYVKEFNYDEFQGYLSGLGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLIKIKVDNMRNQHEAQVQKIDNEPTKA
                     EAKEFGLIAVVAGDGLAEIFKAQGVDYVISGGQTMNPSTEDIVKAIEAVNAKQVIILP
                     NNKNIFMAAQSAAEVVDIPAAVVETRTIPQGFTSLLAFDPSKTLEDNVADMTASLSDV
                     VSGSVTLAVRDTTIDGLDIHENDFLGMVDGSIVVSNPDMEATLKTTFDHMIDEDSEIV
                     TIFIGEDGSSEVAQGLADYLEETYEDIEVELHQGDQPVYPYLMSVE"
     gene            complement(14814..15179)
                     /locus_tag="TV188_000947"
     CDS             complement(14814..15179)
                     /locus_tag="TV188_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1534320.1"
                     /translation="MTVKINTKDGLIELSDDVIATVVGGSATEIFGVVGMASKSALKD
                     NFQSLLRKENYAKGVVVKSTDMGISVDVYTVMSYGVKISEVSKNIQERVKFNLESQLG
                     LSADMVNVYVQNIKVVGEN"
     gene            complement(15331..15519)
                     /locus_tag="TV188_000948"
     CDS             complement(15331..15519)
                     /locus_tag="TV188_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEL1534321.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRTVKPNLQKVTILVDGKP
                     KKVWASARALKSGKVERI"
     gene            complement(15979..16344)
                     /locus_tag="TV188_000949"
     CDS             complement(15979..16344)
                     /locus_tag="TV188_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534322.1"
                     /translation="MADLSISKKSLLKGLGLLSVCLGLAVGTSRTAFAHVSTFYWNRS
                     WYLSQQNKGTDEEVEQKKKELIKKIKDSDLDGFIMGNYIDTINSHVFLYKLLHLEEYI
                     DFLIAQFDHFTPEQLEKRD"
     gene            complement(16934..17815)
                     /locus_tag="TV188_000950"
     CDS             complement(16934..17815)
                     /locus_tag="TV188_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEL1534323.1"
                     /translation="MPIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKQAP
                     VLIQTSMGAAKYMGGYKLAKVLIETLVESMNITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLEKAREIVKLAHAKGVSVEAEVGTIGGEEDGIIGSGELAPIEDAK
                     AMVATGIDFLAAGIGNIHGPYPENWTGLDLDHLKKLTDAVPGFPIVLHGGSGIPDDQI
                     QAAIKLGVAKVNVNTECQIAFANATRAFARDYEANVAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSANKA"
     gene            complement(18018..18103)
                     /locus_tag="TV188_000951"
     tRNA            complement(18018..18103)
                     /locus_tag="TV188_000951"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(18067..18069),aa:Leu,seq:aag)
     gene            complement(18158..19084)
                     /locus_tag="TV188_000952"
     CDS             complement(18158..19084)
                     /locus_tag="TV188_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEL1534324.1"
                     /translation="MKTIRLSKYFGILLLLLTLASVGASFYFFHVAQVREEKSFINNK
                     KRTPDNPLYPAELAFDSLTREKRSITNRGRQQVAWYLPASQDTHKTAIVVHGFTNDKE
                     DMKPYAMLFHSLGYNVLIPDNEAHGESEGDLIGYGWNDRLNLLAWIDLLVSEDKGSRI
                     SLFGLSMGAATVMMASGEQLPSQVVNIVEDCGYTSVWDELKFQAKAMYNLPAFPLLYE
                     VSALSKIRAGFSYGEASSVKQLAKNKLPVLFIHGDKDTFVPTEMVYQNYQATKGPKEL
                     MVVKGAKHAKSFETNPDQYKEKIAAFLQKYEK"
     gene            complement(19444..21057)
                     /locus_tag="TV188_000953"
     CDS             complement(19444..21057)
                     /locus_tag="TV188_000953"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEL1534325.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NIDPGTMSPYQHGEVYVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITDALKEKIKRAATTTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGSENVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPVE
                     QGIKNKLAQFCDVNPEAVIESRDVEHLYQIPLNLQAQSMDQIVCDHLKLDVPQADMTE
                     WSAMVDRVMNLKKTTRIALVGKYVELPDAYLSVVEALKHSGYANDTAIELDWINANDL
                     TAENAKKLLGQADGIIVPGGFGQRGTEGKIQAIRYAREHDVPMLGICLGMQLTCVEFA
                     RHVLGMEKANSFELDPDTAYPIIDIMRDQIDIEDMGGTLRLGLYPCKLKAGSRAAAAY
                     NNQEVVQRRHRHRYEFNNKFRQDFEAAGFVFSGVSPDNRLVEIVELPEKKFFVAAQYH
                     PELQSRPNRPEELYTAFVTAAVKNKNQSL"
     gene            complement(21331..21897)
                     /locus_tag="TV188_000954"
     CDS             complement(21331..21897)
                     /locus_tag="TV188_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEL1534326.1"
                     /translation="MKLDVFAGQEISELSMIEVARAILEERGRDNDMYFSDLVNEIQN
                     YLGKSDADIRYALPFFYTDLNTDGSFIPLGENKWGLRSWYAIDEIDEEIITLEDEEDG
                     APKRKKKRVNAFMDGDEDAIDYSADDPEDEDFVRESSDIEYDEEDPDDEKSEVESYDS
                     ELNEIIPEDDFEEVDLNEEDEEDEEEEE"
     gene            complement(22164..23447)
                     /locus_tag="TV188_000955"
     CDS             complement(22164..23447)
                     /locus_tag="TV188_000955"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEL1534327.1"
                     /translation="MSTSFENKATNRGVITFTISQDKIKPALDQAFNKIKKDLNAPGF
                     RKGHMPRPVFDQRFGEEVLYEEALNIVLPAAYEGAVAELELDVVAQPKIDVVSMEKCQ
                     EWTLTAEVVTKPEVKLGDYKDLTVEVEASKEVTDEEVDAKVERERNNLAELVVKEEAA
                     VEGDTVVIDFVGSVDGVEFDGGKGDNFSLELGSGQFIPGFEEQLVGAKAGDTVEVNVT
                     FPENYQAEDLAGKAAKFVATVHEVKAKEVPELDDELAKDIDEEVETLDELKAKYRKEL
                     EASKEAAYDDALEGAAIELAVENAEIVELPEEMVHDEVHRSVNEFMASMQRQGISPDM
                     YFQLTGTSQEDLHKQHEAEADKRVKTNLVIEAIAKAEGFEASDDEIEKEINDLAAEYS
                     MPVEQVRSLLSADMLKHDIVMKKAVEVITSSAKAK"
     gene            complement(23796..25205)
                     /locus_tag="TV188_000956"
     CDS             complement(23796..25205)
                     /locus_tag="TV188_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEL1534328.1"
                     /translation="MVTHKTKRFLKALSVTSLTLGLVLSGLAPLAPANLASAQEVQSD
                     NQPVAMKDGAILHAWCWSFNTIKENMSAIKEAGYTSIQTSPINAVIEGAGGSKDLKNW
                     YYHYQPTDYTIGNYQLGTEEEFKAMAQEADKYGINIIVDAVLNHTTSEIKAVSPKITA
                     IDNWTHGNDKIVNFNDRYQITQKSLLGLYDFNTQNRAVQEYMLNYLKRAVADGADGFR
                     YDAAKHIELPGEHNSDFWKVILNNGAKFQYGEILQGDACNEAGYGNIMGVTASNYGKL
                     IRKVLGQGYVKDWDLVNFQVHGVSEDKLVTWVESHDTYANDDEESTKLTDEDIKLGWG
                     IIAARNEGAPLFFSRPRGGGGQNGRFPGESQIGDAGSDLFKDPTIVAINQFRNRMNGQ
                     SEYIRNPGMDQGLVMIERGQKGAVITNLTIVDKDFSSTTTLADGDYKDAVTGTVYHVS
                     NHNITGHLAKKSVAVLLPA"
     gene            25656..26495
                     /locus_tag="TV188_000957"
     CDS             25656..26495
                     /locus_tag="TV188_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HEL1534329.1"
                     /translation="MTFILTYFNQLHLENIMVLVFSKLVSITLLLIFFVIFKKITTAL
                     FEKAIAKSFSYSRQTEARKKTLSKLLHNTLNYVFYFLLIYWILSLLGIPVSSLLAGAG
                     IAGVAIGLGAQGFLSDVVNGFFILFENQFEVGDTVTIAGIEGTISSVGIRTTQVRGFD
                     GTLHFIPNRNITVVSNKSRGNMRALIDIPLYSSTDLEHVTQIIKAVNKREVPNFPQIV
                     GQPNILGPQTNPNGQFTFRVSIFTENGQQFTIYYSFYKLYQEALLREGIKLPTASAIS
                     PLA"
     gene            complement(26591..27151)
                     /locus_tag="TV188_000958"
     CDS             complement(26591..27151)
                     /locus_tag="TV188_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019777568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEL1534330.1"
                     /translation="MNLKVLREEARSILLDIVERSAIKKGQLFVLGLSSSEVLGGRIG
                     QHSSLEVGEVIVKLILEELSFRGIHLAVQGCEHINRALVLEESVAEEYRLEIVNVLPS
                     LHAGGSGQLAAFKYMKQPVEVEAIAAHAGLDIGDTSIGMHVKRVQVPLVPIQRELGGA
                     HVTALASRPKLIGGVRARYQPDPIRK"
     gene            complement(27164..27637)
                     /locus_tag="TV188_000959"
     CDS             complement(27164..27637)
                     /locus_tag="TV188_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1534331.1"
                     /translation="MKQTRELALVSILTALTVVLGRFVSIATPTGFLSLLDAGVYVTA
                     FSLGKKEGMLVGGLSAFLLDLISGYPNWMLISLVAHGAQGYLAGLPGRHRFLGVGLAS
                     VIMVGLYFLAAIPMYGMGAAISEISGNAAQNTLGIGVGYLLYLGVKKQLVKVSDD"
     gene            complement(27643..28392)
                     /locus_tag="TV188_000960"
     CDS             complement(27643..28392)
                     /locus_tag="TV188_000960"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEL1534332.1"
                     /translation="MKNKVLTIAGSDIFSGGGLQADLAVLHQLDSFAFLAITCLTSCD
                     AKGFSIHPVATDLLAKQLSSLAAIPFQAIKVGLLPRPEIAEQVALFLELKKDIPVVLD
                     PVLVFKENQDQTVVEMTQALRSLFPLTAVITPNLREAERLAGLAINSREQMVEAAKKL
                     YEMGAKRVVIKGGNRFDQRVALDLFYDAKTLCFLEKPVLAKQNSGAGCSFAAAIAAYL
                     AKGYSPLRAVEQAKDLVFEAIQQSNDYGVVL"
     gene            complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TV188_000961"
     CDS             complement(28382..29131)
                     /gene="truA"
                     /locus_tag="TV188_000961"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEL1534333.1"
                     /translation="MTRYKAIISYDGTLFSGFQRQSQARTVQEEIEKTLQKLTGGQGI
                     QIHGAGRTDAGVHAYGQVIHFDLEQKRDPEKLRFALDTQTPDDIDVISLEIAADDFHA
                     RYHKHFKTYEFLVDIGRPKNPMMRHYATHYPYPLDIAKMQAAIKDLVGTHDFTGFTAA
                     GTSVKNKVRTITAATLTQDPKTGFLVFTFSGNGFLYKQVRNMVGTLLKIGNGRLPIEQ
                     IRLVLESKNRQLAGPTAAGNGLYLKEIIYEE"
     gene            29318..30682
                     /locus_tag="TV188_000962"
     CDS             29318..30682
                     /locus_tag="TV188_000962"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEL1534334.1"
                     /translation="MKVTKFGGSSLASAQQLEKVLAIIKDDPERKIIVVSAPGKRSPT
                     DTKVTDALIAYYKAYVSDRHYHKHLEWIINRYQQICNDLTLDSKIITQIKASLEQLAR
                     LPKEHNPYLYDTFLAAGEDNNAKLVAAYLKANGLTASYLHPKDAGLIVSSEPQHARLL
                     PISYDKLEALKDHDDILVIPGFFGVTNENQICTFSRGGSDITGSIIAAGVTADSYENF
                     TDVNGIFAAHPGVVKQPQTITELTYREMRELAYAGFSVLHDEALIPAYRGKIPIVIKN
                     TNNPSHPGTTIVLEHQRKSNPVVGISGDDHFVSINLSKYLMNREIGFGRKLLQILEDL
                     NIRWEHMPTGIDDLSIVLRERELTPIKEEEILRRLVQQLEVDEVSITRNLSIIMIVGE
                     NMKSHIGVTSAATKALSEHHINIAMISQGSSEVSVMFVINSTDEKKAIRALYQTFFSP
                     DRPL"
     gene            complement(31160..31645)
                     /locus_tag="TV188_000963"
     CDS             complement(31160..31645)
                     /locus_tag="TV188_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComX"
                     /protein_id="HEL1534335.1"
                     /translation="MTDDLVRLFDKIKPIIMKLRQHYYIQLWELDDWLQEGRLILYRL
                     LVTYPELIEDEEKLYRYFKTKFSSYLKDVLRQQESQKRRFHKMAYEEIGSVGHAIPAG
                     GLGVDDYVAYQLIVKEVEERLTEGELSQFRALIRGERFEGRRALLRKIGPYFQDFTGE
                     K"
     gene            complement(31734..31807)
                     /locus_tag="TV188_000964"
     tRNA            complement(31734..31807)
                     /locus_tag="TV188_000964"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(31771..31773),aa:Arg,seq:acg)
BASE COUNT         9542 a         7719 c         5808 g         8992 t
ORIGIN      
        1 gccaagaagt cttttttatg ccttaggtat ttaaaaacta acctcttggg ttagtaccta
       61 tgtcttttaa aaagcctatc catcaggtca ccctaatgga taaggtcaat gtagctgctt
      121 cttgactagc caactgatcc ttccatttca taggcgatca agcgattcaa ttcaacagca
      181 tactccattg gtaattcctt ggtaaagggc tcaacaaacc ccatgacaat catttcagta
      241 gcttcgctct ctgacagtcc ccgactcatc aggtaataga gctgctcctc tgaaatcttt
      301 gaaacttttg cttcatgctc aagagctacc tgagagttgt gaatttcatt gaaggggata
      361 gtatctgatt ttgagatgtc gtccatcagg attgtatcac attcgatatg agagactgat
      421 ttttttgaca gcttgttaaa ggtaacctga cctcgatagt caaccttacc accacttttt
      481 gcaatagatt ttgacacaat agacgatgag gtgtgaggcg cattatgcac catcttagct
      541 cctgtatcct gatgctgacc agtattagca aaggcaatgg agagcatggt gccacgcgca
      601 cctggaccat caaggtaaac tgaagggtat ttcatggttg ttttagcacc cagattacca
      661 tcaatccact caaccgttgc gtccttgaga gcacgcgctc gcttggtcac caaattatag
      721 acattgtcag accaattttg aattgttgta tagcgcatgt aagcaccatc taaagcaaag
      781 atttcaacaa tagcagcgtg caagctgttg cttgaatagg taggtgctgt acagccctcc
      841 acataatgca cactagcgcc ctcatcaaca ataattaggg tacgctcaaa ctgaccagtg
      901 tgttcattat tgatgcggaa ataggtttgc aaaggaatgt ctaccttgac cccctttggc
      961 acataaataa aggtccctcc tgaccaaaca gcagaattca aggcggctaa tttgttgtca
     1021 gttgggggta ccagcttagc aaaatactgc ttaaatagct caggatattc ctttaaggca
     1081 gaatccgtat ccgtaaagat aatgcccagc ttttcaaact cagccttcat gttgtggtaa
     1141 accacctcag actcatattg tgctgaggcg cccgccagat aagctcgctc tgcctctgga
     1201 atgccgatgc gctcaaaggt ttccttgatt ttatctggaa catcatccca tgaacgagcc
     1261 ggcttatcag atggcttttg ataatagata atctcatcaa aatcaatatc tgaaaggtct
     1321 gcgccccagg tttgcatggg cattttatga aaggcttcaa gtgattttag gcgaaattcc
     1381 agcatccact ctggttcatc tttagcagct gataattctc tcacaactgc ttcatttagg
     1441 cccttacctg ttgagtagat aggctcaaca tcgtcatgaa agccaaattg ataatcacct
     1501 aaatcaattg gctggggggc tactgtttca tttatatcag acattttcta ttttccttta
     1561 tacgttacta aatgagagag gacttaaaac tcatcgcttt tttcaatagc ctgcttgaga
     1621 gcatgccaag ccagagttgc gcacttgata cgctgtggaa agttggcaac cccagctaat
     1681 agctcagctt cacccaagag agcctgattg ctatcgtcat ttccctgaac catatttgaa
     1741 aaaatgtcag ctagggccaa cgcttcttcc tttgtctttc caaggacagc atctgtcatc
     1801 atactagacg aagcagtcga aatcgtgcag ccatccccgg caaaggcaat atcctcaatc
     1861 ctgtcatcag caaatttgat agtaagggaa atcacatctc cacaggtagg attatgaagc
     1921 tggactgcct ctacaccctc aagctggcca tgatgatgcg ggtgtcttga atgatcagcc
     1981 acaacagcca tatataagct gcttaactta gaaagtgcca ttaaaaaact cctttgcttt
     2041 taaaatagct tctatcaagc gatcgcaatc ctccctcgta ttatagagat aaaagctagc
     2101 acgaactgtt gaatgcagtc ccaagtactt atgcaaaggc tgagcacaat gatgtcctgc
     2161 tctaactgca acgccctcat aatctaaagc cgttgcaaga tcatgcgggt gtaagccatc
     2221 tatattaaag gcaaggacgc ctgagcgttc atctgatcgg tcaggaccat ataccgtcaa
     2281 gccagcaata gcctgcagcc ttggcaaggt ataagcaact aaatcagcct catgagcatg
     2341 aacctgatcc attcctatag cctccaaata tgaaatagca gctccaagac caatagcacc
     2401 agcaatatgg ggggttcctg cctcaagctt ccaaggcaag ggcttccaag tcgcctcctg
     2461 ctcataaaca aaatcaatca tttcgccacc aaattcaact gggttcattt ggttaaggag
     2521 agcctccttg ccatacaata caccaatgcc agtcggtccc agcaacttat ggcctgaaaa
     2581 ggcaaggaaa tcacaatcta actcctgcac atcaatagcc atgtgcggta ctgactgcgc
     2641 agcgtcaacc acaaaatagg caccccgagc atgagcaagc cttgcaatct cctgaatcgg
     2701 attaacacag cctaacacgt tagagacatg ggtgatactg acaaatttgg tgctagcacc
     2761 caattttgat tgcagatcat tcatgtctag cttgcctttc ttaagataag catagacaag
     2821 ccttgcccct gttttttgac aaacctgctg ccaaggaagg atatttgcat ggtgctccat
     2881 aatcgaaatc agcacctcat cacctggctt taagacctgc tcagcaaatt ttccaaccca
     2941 atttaagctg cttgtcgtcc ctcttgtgaa aatcacttcc ttgcttgact tagccccaat
     3001 aaagtcagca accttttgac gactagcctc atactgtctt gttgctcttt ctgccagggt
     3061 atggacacct ctatgaacat tggcattatc cttttgataa taggcctgca tggcctctaa
     3121 cactgcctgt ggcttttgtg ttgtcgccgc attatctaag taaacaagag cctcatcatt
     3181 tacatattgg tcaagtagtt taaagtctgc tttgatttga ttaggatcaa acaatgataa
     3241 ctcctttctt tgactagtaa ctaacgacgt gccagcttat catctaaggc agtaacaata
     3301 tcctgacgaa ccgacggcac agggatttct gccactaccg cacctagaaa acctcgaata
     3361 acaagacgct cagcagtctc ttggtctagt cctctactca ttaaataata catgtcctca
     3421 ggatccacct gaccgataga ggcggcatgg cctgctgtta cctcattttc atcaatcagg
     3481 agaataggat tggcatcaga gcgagcctga tctgacagca ttaggacacg actttcttgt
     3541 tgggcatcag caccctttgc tcccttaatg atatgaccga tagcattaaa tgtcaatgtc
     3601 ccgcgctcca agataacccc atgctgtaaa atatgcccaa ccgtatgttt tccataattg
     3661 gttactcggg tatcaatccc ctgaacttga cgaccacttg aagcagcaac caccttcaca
     3721 tcagcctgtg agccttgacc gatcaaatca ctatcaaagt cagcaatgac attgccctca
     3781 ttcatcagag caagcgccca atcaatagtc gcagcatgat ctaagcggcc tctgcgactg
     3841 atataggctg tcacctgatc acccaggcga tcaatcgccg aaaacttaat ctgacttccc
     3901 gcctgagcaa tgacctcaac actaatattg gcactagctg cttgggtctt gtctcctata
     3961 gactcaaagc gctcaaggta ggtcagctta ctttctttac ctgcaatgat gagcacatgc
     4021 ttgttaaagg ggacatcact atcaccatct tgcaagaaga tcccttcaat tggctgctca
     4081 atctcaacat gatctggaac atatagcaca gccgcactgt taaaataagc cgtatgatag
     4141 gccgccagtc tatgctcatc aaaggctaag gcagaaccaa aatgagcctc aagctgctcg
     4201 ggaatctcat ctagagctgt agcaaggtct gtaaaaacaa ctcccttttc gatcaattcc
     4261 ataggaagct gctcaagaac cgtctgtgtt ccgacctgaa ccagcttagg attatcaccc
     4321 aaggccataa aatctggaac agttcctaaa gcagtgcttt ctgtcaggct accatcacca
     4381 aagttccaac ggtgaaattt aacccgttca atagtaggca gctctaaatg tggcatcaca
     4441 tcaaaggcct ttaagcgcag ctcttgcagc caagtaggct cagcatgcgc ttgagaaaag
     4501 gccaatatct tttcttttgt catctatcct tccttttttc tggtaagctt ttcaatcatc
     4561 agcaaacata ctaatcagca cagctatggc gaagccttag acagccttgc agcttagacc
     4621 tcttctttat agtcaatgcc tagctcctca gcaatgcctg catagccttc tttttcgagt
     4681 cgtatagcaa gtgcagcatc ccctgatagg actatccgac catccatcat gacatgcacc
     4741 aagtccggag tgatgtaatt aagcaagcgc tggtaatggg taataatcat cgcaccaaat
     4801 gcctgaccac gcatctcatt aacccctttt gacaccacct ttagggcatc aatatcaagc
     4861 cctgagtcaa tctcatctaa cagcgcaaac ttaggctcta gcatgagcaa ttgcagaatt
     4921 tcatttcttt ttttctcacc gccagaaaag ccttcattga ggtagcgctc tgccatttcc
     4981 tccttcatgc caagcagggc catcttctca tctagcttgg taatgaagtc acgaacagaa
     5041 atcttatccc tgtcctcttt ccctgcattc atagcggctc gcataaattc ggcattggta
     5101 atccctggaa tctcagacgg gtattgcatc gctagaaaaa gtcccagtct agcacgctca
     5161 tcaacctcta gctccagaat attgacacca tctagtaaaa tctcaccctc tgtcacttga
     5221 tagttgggat tgcccataat cgctgctgac agtgttgatt ttcctgttcc atttggcccc
     5281 atgatagcag caatttcacc tgtccttagg gttagattga ccccctttaa aatctcttta
     5341 tcctctatcg aaacatgcaa attgttgatt tcaagaattg acattgtata cctcatcatt
     5401 tctattaggc tctttcagta tcttctttcc tgaaaatagc ctaatgcttt cattatcttc
     5461 attataacaa aaaaagcctc agcaggcttt ttacttgtct gaaatcattt cctttgcttc
     5521 cattttgaaa gcgtcgtctg acggtaatcg ctattaccga taaacttcaa gaggttgaat
     5581 aggggcgttc gtttttctcc ccagatttca ataccttcaa taaagacctc tagggcaaat
     5641 aagagtccca agataagcaa gaccccacca atacgactag agacattcaa caaaagagag
     5701 atcaaggaaa agagcatagc aataccgtaa acaaccagca ctgcaccgcg atgtgtaaac
     5761 cccattgaca agagacggtg atgcaggtgc atcttatcag gctcgtaaaa tttctttcca
     5821 gacaggcttc gacgaataat cgccacaatc gtatccataa ttggaacacc taaaataata
     5881 accggtgtaa caacggctac cgcagttgca tttttcaagc cctgcaatga taacacacca
     5941 atcataaagc cgataaaaag cgctcccgta tccccaagat aaataatagc cgggtgatag
     6001 ttatagggaa aaaagccagc aatagatgca atcaggatta aaatcgtcag ggttaaaaag
     6061 aaatttgtca atggcaaaaa gaaataagct acaatagcca ttgttactaa gctaataatc
     6121 gaaacaccac tgactagacc atctaagcca tcaataagat taatcgcatt ggtaattgag
     6181 ataatccaaa gaacggttaa aaagaaggtc aagaaaggat caaaagccag caagggtcca
     6241 ccaaaaggaa tcttaaagct atcaaattta aagtcagtaa aggcccagac aataatggca
     6301 ccaatgacaa ttcccagcat tttcagctta ggacttagct catacacatc gtctataaag
     6361 cctgttatgg taaccaccaa gcctcctaag acaactggca aaatatactg aaaataggtt
     6421 tgcccgccaa tatgagcacc atttgatgcc agaggcatca gtaccagact cgcaatcaca
     6481 aaggaagtaa agatagccaa gcctccacta gtcggcatgg gaaccttatt aatccgtcta
     6541 gcatttggag tatctaccac accgactcta atgcttagaa aacgtacaat tggcgttaat
     6601 aaaagtgaca tcagcaaggc accaattaaa accaagacat catctatcgt gaacgaaatc
     6661 atcataccct accccaacct gattttttgc agctcctcaa cagcaccatc aaaaatgagc
     6721 tgacaaccat gctcctgcaa ataagctctt gtttttgttc caggactagc atgctcaatc
     6781 aatctggcat acatcacgtt ggcaaagtag gcaggcttgt tttgcacatc aagtaaaatc
     6841 gtcatgtgat aatgacgagg acccttatac aattcagaag cctcgatcgg aaaatcaatc
     6901 accttagcaa agcaaacagc gtctcgaaca gaagcaaaat caagaacata gtgaacataa
     6961 tcaagtggct ctgtcggctc atcaagctca gcagcttcct tactatctgc ttgctcagcc
     7021 aaggtagcat caaccacgtc ctccatgatc tcctcgattt tttcaagctt ttcatgggca
     7081 ttgacatcac ccttttcacg catagactgc tccaagcttc tgaaaaaatc ctctggagtc
     7141 atttgagaaa tatcacctag gtctgccaaa tcctcaaaat taaggtcctt attgaggtct
     7201 gatttggtca caaaaacatc taagcgatcc tttcttggag tcactcgaaa gctaagcata
     7261 ccactgtcct taaaattgtc cggaaggccc aactcgtcca tgacagcata aaagaactcc
     7321 tctgtctttt cttgagggat caagaagtcc ttgagctcca tccccctttc ttctaaatcg
     7381 tccatactaa ttgttatttt tagcgttgtc tcgctaattt gtttcatttc cattgtaaaa
     7441 tacctcgcag gcgtagtcat tttattatac tagaaatact atgatttcgc aatttatgac
     7501 tagccttaca gcaagtaaaa gcagccttcc taggaaaact gcctgacgat ttctaaaaaa
     7561 gtgacttaaa tacactgtag acaatcaata agcttcccaa cacaatccgg taccgcccaa
     7621 agactgtaaa atcatgcttt ttaacataat ctgttaacaa tttgatcaca tacaaactga
     7681 ctgcaaaggc tgttaggctg gcaactaaaa gcactaatag ctgcgagagg gtcaaatggt
     7741 tgccatcaat aaaaaacttc aaagctttta ggccactata gccaaacatc gtcggaatgg
     7801 ccaaaaagaa ggtaaagtcc gcagcaactg tcctgcttgc tccaagaata atcgccccta
     7861 aaatcgttgc tcccgaacga ctggtcccag gaataatgct aagcacctga aagcagccaa
     7921 taaagaaggc tgttttatag gacatacgag atagcttgac gactcgcggc tcaagtgtct
     7981 gatttctctt ttcaatccat aaaaaggcta tcccataaac aatcaatgca atagcaatag
     8041 gaagcatatg attaaaatga gcgtcaaacc aatcatcaag tggtactgca atgataatag
     8101 acggaataca agcaatagca accttaagcc acagctgcca ggttagcctg atttgctgtg
     8161 ggctcttgcc aggctgaaaa gggttcaagc gttcaaagta aataacaata accgcaataa
     8221 tcgctcccag ctgaataaca atattaaaca tctccataaa ggccttatcc tgatgaagtc
     8281 tgataaattc ctgaaccaaa atcagatgtc cagtactgga aataggcagc cactcagtaa
     8341 ctccctcaat aacaccaaag aagatggcct tcagcaattc aataaataac atgttccctc
     8401 cttctaacaa agactctcat atctagcccg tcctaaaaga acaccacttc ctcctccatt
     8461 gccagcggag aagccgcaac cacagtcacc aagcaacagc aatggggtat tgcttttttt
     8521 gcttgttcat attgtaccat aaatgacacc gttaataaat cagtgacttc ataagaaaaa
     8581 gcttattttt aatcatttct tcacttgttt tatgaataaa taatcacctc ttttaaccaa
     8641 tgtattgaaa tagcttgtaa attactatag aatagtatta aacacgtttt taaaaaagga
     8701 gacctatatg aaaaagctag tccttagctg cttggccacc ttacttattt ttcttggagg
     8761 aataggtact gtgcaagcag atcactattt acgagttggt atggaggcgg cttactctcc
     8821 atttaactgg actcaagatg attcgtcaaa tggcgctgtt cctatcgaag gaaccagcca
     8881 atacgccaat ggctatgatg tgcaaatcgc taaaaaaatt gcaaaagcat taaacaaaga
     8941 cttattggtt gtgaaaacct cgtggacagg tcttattccg gctctgacct caggtaagat
     9001 tgatttaatt gcagctggta tgagcccaac agcagagcgc aaaaaagaaa ttgccttttc
     9061 taacagctac tacaccagcg agccagtcat tgttgtcgcc tcaaatggta agtatgccaa
     9121 ggctcgttct atcaaagatt tttcaggtgc taaggtaact gctcaacagg gcgtgtggca
     9181 tgtcaacctg ctaccacagc tagagggggc aaagcttcaa acaccaatgg gagatttttc
     9241 tcaaatgcgc caggctctaa cctctggagt gattgatggc tatatctccg agcgccctga
     9301 ggcaatgaca gccgagactg ccaacaaagc ctttaaaatg atcactctaa caaaaggatt
     9361 taccgtttca gagtcagacg ctgccattgc cattggcatg aaaaaaggag acgaccgcct
     9421 tacagcagtc aatcaagtgc ttgatgccat ttctcaaaag gaacgccttg ccttgatgga
     9481 caagatgatc caacagcagc caagcgagcc caaagctgat gaagcaaagc cctcctttat
     9541 caagcaaacc tggtcaatct ttcaaagcaa ctggaagcag ttccttcgcg ggacaggcat
     9601 gaccctcctg atttcgatga ttggtactat cacaggactt ttcatcggtc tcttgattgg
     9661 tatttaccgt acagcaccaa aggctaaagg caaattggca gcgctagctc aaaggctctt
     9721 tggtggacta ctcaacgtct atatcgaagt ctttcgtggg acgccaatga ttgttcaatc
     9781 aatggtgatc tactacggca ctgcacaggc ctttggcatt tccattgacc gcacactagc
     9841 agctatcgtt attgtctcaa tcaacacagg tgcttacatg agtgaaattg tccgaggcgg
     9901 tatctttgca gttgacaaag ggcagtttga agcagcaaca gcccttggct ttactcatgg
     9961 gcaaaccatg cgtcagattg tccttcctca ggtggttcgt aatatcctac ctgctactgg
    10021 taatgagttt gtcatcaata tcaaggatac ctctgtcttg aatgtcattt cagtggttga
    10081 gctatatttc tcaggaaata cagtggctac tcagacttat caatacttcc aaacctttac
    10141 cattatcgct attatttact tcgtcctaac ctttacggta acgcgtatcc ttcgctatat
    10201 cgaacgtcgc ttcgatgctg atacttacac taccggagca aaccaaatgc aagtttcgga
    10261 ggtcccaaat gtctaatccc attattgaaa ttaaaaacct aaaaaaatct tacggcaaca
    10321 atgaggtcct aaaggacatc tcgctaaccg tcaataaagg agaggtgatt tcaatcatcg
    10381 gttcatctgg atcaggcaaa tcaaccctcc tacgctcaat caacctatta gaagagccta
    10441 gcgccggaga aattctcttt catggtgaca atgtgcttgc agaaggctac aacctgaccc
    10501 attaccgtga aaaattgggc atggttttcc agtccttcaa tctctttgaa aatcttaacg
    10561 ttttagaaaa tgcaatcgta gctcaaacaa ctgtcctcaa gagagaacga tcagaggctg
    10621 aaaaaatcgc caaggaaaat ctcaaggcag ttggcatgac cgagcaatac tggcaagcca
    10681 agcctaagca gctatcaggc ggacaaaagc aacgtgttgc tatcgcccgc gccctatctg
    10741 ttaaccctga agccatgctg tttgatgagc caacatcagc tcttgaccca gaaatggtcg
    10801 cagaggtctt aaaaaccatg caagatctgg ctaaatcagg cttgaccatg attattgtca
    10861 ctcacgaaat ggagtttgca agagatgttt ctgaccgtgt cattttcatg gataaggggc
    10921 tcattgcaga agaaggcacg ccaaagcagc tctttgagca gccaaagcag gaccgaacca
    10981 aagcattttt acagcgcttt ttgtcataag cctaaaagcc agtctaacca taggtgttag
    11041 attggctttt tttgataagt cacatctgct aagcagcata atgatcatat agactacttt
    11101 agatcaaaga aaagacctat tataggacaa tttccctcaa caggcacaga taataaacct
    11161 ccttttgaag gttgtgctgc tactttttca aagctgctaa ggcaactggt ctacaaaaat
    11221 catttctcaa atgagacggt aactgttaag cttgatctct attctaaaat ttcaacacaa
    11281 aatactttac tggttaataa ctttgtgcta tactgtcttt attaacgtta ataatatatt
    11341 ttagtaggag gatagcatgg ccgaaaaaac tgacctcgcg tcagcttaca gaagactaaa
    11401 aagcccaaat attaaaacta aaaaacgtgc tctgaagatt attcacgagc acaaacgtta
    11461 cggtaaaaaa tagtattcta tttttatctc tccaaattta agtcagataa aaaatgatta
    11521 ggacaccatc cctccgtctt aatcattttt tgatggccaa gaaaagaaag ctttaagcat
    11581 tgttaaccat caacaagctg aggacacaca catctgatag agctgccaat agtagcagtt
    11641 aggaaatgct acactcagct tttaggtcca tgcttcagca ttttcaagca accggatacc
    11701 aagaaaacta accttttagc acagcacaaa gcggcacttg aactcacttt gttccctcat
    11761 ttgctctctt agcggctaag cttcaaaggt gattgaaaca acccattgca attggtctag
    11821 cttccaagct gtttgagcct gtgattcttg ctagcatttc agacatagca acatttttca
    11881 atagccatta tgcttaagac aatagtgaaa taaagacgac tgccttactt ttcaagaaca
    11941 ttgacgagcc atcatacaaa aagcaagctg atgctgacca gcttgcttaa tatatattat
    12001 cttgttttta aggctgatag cacctgagtg cgaatatcat caacaccatt tagagtattt
    12061 ggtaggaaaa gggtctgatt accctttgca gcaaaggtat tgagggtatc taagtactgg
    12121 ttggtcagaa gaattgacat gatctgctct tcattcagtg aaatattagc ctccttcaat
    12181 tcctgaatag aatcagccaa gccatcaaca atagccttac gctgctgtgc aataccaaca
    12241 ccatgcaggc gatccttttc ggcttccgct tctgctgcag ttacaatttt aatcttatca
    12301 gcattagcca attcctgtgc tgccacacgc ttacgctgag cagcattaat ttcattcata
    12361 gactgcttga cttcagcgtc tggctcaacc tttgtaatca aggtctttac aataatatag
    12421 ccataggttg acatttcttc tgctacctga tgctgcacct ccaaggcaat ttcatctttt
    12481 ttctcaaaca attcatctaa ggttagcttt ggaacagaag agcgcaaggc atcttcaata
    12541 taagacctaa tttgagcctc tggcttgatc aatttgtaat aagcatctat cacattttgc
    12601 tcattcacac gatattgagt cgcaacattt agcgtcacaa aaacattgtc cttggtcttt
    12661 gtttcaacaa taatctctga ctgcagcaaa cgcaattgca cacgcgcagc aatgcggtca
    12721 atcccaaagg gcaatcgaat atgaatacca ctagtagctg taccttgata tttaccaaag
    12781 cgctctataa tagcaacaga ttgctggcgc accacataca gcgtgcttgc cataatggat
    12841 aatatcacaa tcaccagaaa tccaataatc aaaatagctt ctaacatgtt aatctcctcc
    12901 ttataaagcc ctagctggat agctatacgg ctttttatga ttgcctcatt gttataagac
    12961 aattataaaa catttttgtc ttttgtcaat aaaaatctca acgtctatca gccggcttta
    13021 cagctgctag agaccactaa aagtctacac ctgacgacag gctgcaatca ttgcttctta
    13081 atagtcaagt cttccttcca aagacaaaag gagctaagcc ttgcctaact cctctctttg
    13141 ttctattcat tattcaacac tcataaggta tggatacaca ggctgatctc cctgatgcaa
    13201 ctcaacctct atatcctcat atgtttcctc gaggtaatca gcaagacctt gagccacttc
    13261 actgctgcca tcctcaccaa tgaagatcgt aacgatttcg ctgtcctcat caatcatgtg
    13321 atcaaaggta gtctttaggg tagcttccat gtctggattt gacactacaa tgctgccatc
    13381 gaccattcct aaaaagtcat tttcatgaat atcaaggcca tcaatcgttg tatcgcgcac
    13441 agccagagtc acacttccac taaccacatc agacaggctt gctgtcatat cagctacatt
    13501 atcctccaaa gtttttgaag gatcaaaggc cagcaggctc gtaaagcctt gtggaattgt
    13561 acgtgtctcc acaacagccg caggaatatc cacaacctcg gctgctgatt gggctgccat
    13621 gaagatgttt ttattgtttg gtaagataat cacctgctta gcattgacag cttcgatagc
    13681 cttaacaata tcctcagtag atggattcat ggtttgtcca cctgagataa cgtagtcaac
    13741 cccctgtgcc ttaaaaatct ctgccaggcc atcacctgca acaacagcaa tcaggccaaa
    13801 ctcttttgcc tctgccttag taggctcatt gtctattttt tgtacctgtg cctcatgctg
    13861 attgcgcatg ttatctactt taattttgat cagtgagccg tacttcagac cctcttgcat
    13921 cactagccct ggatcctctg tatggacgtg aaccttaacg atctcatcat catttactac
    13981 taaaagcgaa tcaccaagcc cactcaaata gccctgaaat tcatcataat taaattcttt
    14041 aacataggta ggaccctgct ttagagcaac cataatctca gtacaatagc cataggtaat
    14101 atcctcggta gcaacatgac ctgcaactga tttgtggtgc tcagccttaa tcatctcaga
    14161 catattggca ggagtggcct taaagtcctc agaagctaca taatcaccat ttaaggcaga
    14221 caagaagccc tcgtaaataa agacaagacc ttgacctcct gagtcaacaa caccaacctc
    14281 ttttaaaact ggcagcaggt ctggtgtttt tgcaagggct ccttttgcac catctagcgc
    14341 tgcttgcatc acctcaatgg cattatcagt aaggtctgcc tttttcaagg ctgctgttgc
    14401 tgcaccacga gaaacggtca aaatagtccc ctcaacaggc ttcatcaccg ccttgtaggc
    14461 aacctcaact cccatctgaa aggcctgagc taaatcctta cctgtcagct cctcttttga
    14521 cttgatactt tggccaaagc cacgaaaaag ctgcgaggta ataacaccag aattgccacg
    14581 cgcccccatc aagagaccct tggataggat ctgcccaacc tcaccaaccg ttgaagccgg
    14641 cttatcagca acctctttag caccattatc cattgtcatg ctcatattag tccctgtatc
    14701 accatctggt acaggaaaaa cgtttaagga attgacatat tctgcttgtt taccaagacg
    14761 agttgctgcc gcttggacca tttcttggaa taagcttgtt gtaatatttg acactaattt
    14821 tctcctacaa ctttaatatt ttgcacgtaa acattcacca tatccgcaga aagcccaagc
    14881 tgactctcaa ggttaaattt cacacgctcc tgaatatttt tggatacctc actaatttta
    14941 acaccgtagc tcataacagt atagacatca actgaaatac ccatgtccgt tgacttaaca
    15001 actacaccct tagcataatt ttctttgcga agtagcgatt gaaagttatc ttttagagca
    15061 cttttactag ccataccaac aacgccaaaa atttccgttg ctgaacctcc aacgacagtt
    15121 gcaataacgt catcagatag ctcaattaga ccatcttttg tattaatttt tacagtcata
    15181 gttactacct caaaaagttt ttatcagctt attttatcat aattcaaggt caatgtaaaa
    15241 agatataagc gaagaaaggt cacctctatc atgcttttct aagctttttc tgaaaacgac
    15301 taagaaaaaa agccctaagg cttatttcga ttagatgcgt tctactttac cagatttaag
    15361 cgcacgagct gaagcccaaa ctttttttgg tttaccatca acaaggatag taactttttg
    15421 aagatttggt ttaacagtac gttttgtttg gttcatagcg tgtgaacggt tgttaccaga
    15481 tacagtctta cgacctgtga aataacatac tttagccatt gtaatctatt tcctcctagg
    15541 tagaatatgt ttacggatgt gctagcacca catacttacc tagtctatca caactcttac
    15601 cttttggcaa gctatttttt acatctgcag gccttagcca ctaagcagca aaatgtccct
    15661 cttaatagct aagcactcac ttgctcctct cctataaata ggtctataag aatcaataat
    15721 accctatcta tcacaaatgt ctaagggctg ctgtcagctc gaaagccttc tcttagaacg
    15781 ctaaaactac tctaagaaat agaggttatt taacaggctt tgctgtagtt gcctagctga
    15841 aatcctataa gcatgcacta aaaaagacta aacaagacat cacacaacca cattagtagg
    15901 gagattagcc tgaggagtgc ttcttgttta gtcttttatc ctcttgaaag ccttgatcag
    15961 tatcgtgatt gctgatttct aatcacgctt ctctaactgc tcaggtgtga agtggtcaaa
    16021 ctgggcaatt aaaaaatcaa tatactcttc aaggtgtaaa agcttataga gaaaaacgtg
    16081 gctattaatg gtatcaatat aattacccat aataaagcca tctaaatcag aatctttaat
    16141 cttcttgatt aattccttct ttttttgttc aacctcttca tcagtgcctt tattttgctg
    16201 agacaggtac caggacctat tccaataaaa ggttgataca tgcgcaaaag ctgtccggct
    16261 agtaccgact gctaaaccaa gacaaacaga tagtagtcca aggcccttta aaagagactt
    16321 ttttgaaata cttagatctg ccatagcgag tcctcctttt tatttttcta accaaaccat
    16381 actaaaatat aactatattg taaaataaaa agtattgtat tagaaataag taaaaataaa
    16441 gctatgaata gttgacctaa ctaaacccaa caaataagat gctacatgac aaaattcctt
    16501 ttattctcac cacctgtgat ctcatcaaaa gctctctaaa ccagagaggc atagacagct
    16561 accgaatgaa gccttagtaa tagctgtctc agctcacctt aaactaatag ggtcgataaa
    16621 taaggagaca tttgcgcagc agaagctgat agtgtcaaag gttctacttc agcaagcata
    16681 tcatgagtca cctatttcag cacaggcttg gtaatgtttg gatagtacaa agcgtttttc
    16741 tcaagaacgt tcaagatcct tccagtcata gcagagcagc ccttaccaca gacatctgct
    16801 agcacacacc tcaaaaacaa agacataatc gctcaagtag ggctattctt tatcggcaag
    16861 gggattaggc gaaggaacta taaaaaggcc tatccttgcg gataaaccct gatttaatca
    16921 cgtttagcag tcattaagcc ttgtttgctg agccaaagac atcaatacgt tcttcaacag
    16981 aagcctggat cgccttaaca ccatctgcca agaatttacg tgggtcaaag agttttttct
    17041 tatcgtattc tgcaacgttt gcttcgtaat cacgcgcaaa ggcacgagta gcgttagcaa
    17101 atgcaatttg acactctgta ttaacattaa cctttgcaac accaagcttg atagctgctt
    17161 gaatttggtc atcaggaata cctgaaccac catgaagcac gattgggaag cctggtacag
    17221 catcagtcaa tttcttcaag tgatctagat caagaccagt ccagttttct gggtatgggc
    17281 catggatatt accaatacct gcagccaaga agtcaattcc tgtagcaacc attgccttag
    17341 cgtcttcaat cggagcaagc tcaccactac cgatgatacc gtcttcttca ccaccaattg
    17401 tacctacctc agcttcaact gaaacaccct tagcatgtgc tagcttaaca atttcacgtg
    17461 ctttctcaag gttttcttca actggaaggt gtgaaccgtc aaacatgatt gaagtgtaac
    17521 caacctcgat acattcaaga gcatcttcat agtgaccatg atcaagatgg atcgcaaccg
    17581 gtacagtgat gttcattgat tctacaagag tttcgataag aaccttagct agcttgtagc
    17641 cacccatgta tttagctgca cccattgagg tttggataag aacaggagct tgtttagctt
    17701 ctgctgcacg caggatcgct tgagtccatt caaggttgtt tgtgttaaat ccaccaacag
    17761 catagccgtt atcacgtgct gcttggacaa atttttctgc tgaaacgatt ggcattttaa
    17821 taagcctcct cttatatttt gggttaaccc catttacatt gttcatttta gcacaatttt
    17881 caagaaattt ccagcccctc atcagcttaa agcgttttct cgattcatct tatcacaggc
    17941 tcacaattga gcatttggct agcagcagtc ttttcaggaa ataaaaaaaa agatgaatcc
    18001 aagattcacc tctgcgatgc ggagagtggg acttgaaccc acacgaccta aagcggtcac
    18061 aggatcctta gtcctgcgcg tctgccaatt ccgccatccc cgcttgctct ttagcaacat
    18121 ataaaattat atcagctggg agctttactg tcaatactta tttctcatat ttttgcaaaa
    18181 aggccgcaat cttttccttg tactggtcgg gattggtctc aaaggacttg gcatgcttag
    18241 cccccttaac aaccattagc tctttaggac cttttgttgc ctgatagttt tgatagacca
    18301 tctctgtcgg gacaaaggta tccttgtcgc catgaataaa gaggactggc agcttatttt
    18361 tggccaattg cttcaccgag ctagcctcac catagctaaa gccggcacga attttagaga
    18421 gggctgaaac ctcatacagc aagggaaagg ctggtagatt gtacatggcc ttagcttgga
    18481 atttcaattc gtcccaaaca ctagtatagc cacaatcctc aacaatattg acaacctgac
    18541 taggtagctg ctcaccgctt gccatcataa cggttgcggc acccatggat aagccaaata
    18601 agctaatgcg actgccttta tcctcgctaa cgagcaaatc aatccaggca agtaggttca
    18661 agcgatcatt ccagccatag ccaatcaagt caccctcact ctcaccatga gcctcattat
    18721 ctggtatcag cacattgtag cctaggctgt gaaaaagcat ggcatagggc ttcatgtcct
    18781 ctttatcatt tgtaaagcca tgaacgacaa tagctgtctt atgagtatcc tgcgaggcag
    18841 gcaaatacca tgcaacctgt tgacgtcctc tgttagtgat actgcgtttt tcacgcgtca
    18901 agctgtcaaa agctagctct gctgggtaca aaggattgtc tggggttcgt tttttattgt
    18961 tgataaatga cttttcctca cgcacctgag caacatggaa gaaataaaag ctagctccca
    19021 cactagccag ggtcaacaag agcagtaaaa tgccaaaata ctttgataat cgaatggttt
    19081 tcataccgac tattctacaa gaaaatatgg aaaaaagaaa gctttatgct aaaaataacc
    19141 gatacctttt tactgccttc ttaaggccaa atctcaagcc agccagtagc taaagcgttt
    19201 tcgcaggaat tgaagctcaa tagtttaaag aatatacaag ctaccttcaa aatagctttg
    19261 accagatcaa gaggaagtcc gctgacagca tttgataaga ggtaaaatgg tgctttttgc
    19321 tatattaaaa gtggctgatg tcatcatctc atcagccact caaagactta ataagcctat
    19381 caaagctgct aactctcagc acctaaataa ggctcaagga tagcctctta cgtcatacta
    19441 gacttaaagg ctttggtttt tatttttcac tgctgctgta acaaaggcag tgtatagctc
    19501 ttcaggacga ttaggacggc tttgcagctc tggatggtat tgggctgcca caaagaattt
    19561 cttctctggt aattctacaa tctctaccaa acgattgtcc ggcgaaacac ctgagaaaac
    19621 aaagcctgct gcttcaaagt cctgacggaa tttattgtta aattcgtaac ggtggcggtg
    19681 acggcgctgc accacctctt ggttattgta ggctgctgca gctcttgagc cagcttttag
    19741 cttacatggg tatagcccca gacgtaatgt tcctcccatg tcctcaatat caatttgatc
    19801 acgcataata tcaatgattg gataggcagt atctggatcc agctcaaacg aattggcctt
    19861 ttccatgcct aggacatgac gagcaaactc aacacaggtt aattgcatgc ctaagcaaat
    19921 gcccagcatc ggcacatcat gctcacgcgc atagcgaatg gcttgaattt ttccttctgt
    19981 tccacgctga ccaaagccgc caggaacgat aatgccatca gcctgcccaa gcagcttctt
    20041 agcgttttca gctgtcaggt cattagcatt aatccaatca agctcaatag cagtgtcatt
    20101 agcatagcca gaatgcttta gggcttccac aacagacaaa tacgcatctg gaagctcaac
    20161 atatttccca accaaagcaa tccttgtcgt tttcttgagg ttcatcactc tatcaaccat
    20221 agctgaccat tctgtcatat ctgcctgagg cacgtctagc ttcaagtgat cacagacgat
    20281 ttgatccatt gattgagcct gcaaattcag tggaatttga tacaaatgct ccacgtcacg
    20341 agattcaata acggcttctg ggttaacatc acaaaattgc gccagcttat tttttatccc
    20401 ctgctcaaca ggctcctcag tacgaatgac aagcatattc ggctgaatgc ctaagccgcg
    20461 taattcctta acagagtgct gtgtcggctt tgttttcatc tcgcctgctg cttttaaata
    20521 aggcagtagg gttgtgtgaa tatacatcac attttcagag ccgacatctg ccttcatttg
    20581 acgaagcgct tctaagaatg gcagactctc aatgtctccc acagttccac caacctcggt
    20641 aataatcacg tcagaatctg tggtcgtagc tgcgcgcttg atcttctcct ttaaggcatc
    20701 tgtaatgtgt ggaataacct gaacagtcgc tccaaggtat tcacccttac gctccttacg
    20761 aagcacctca ctgtagattt taccagttgt cacatttgag tatttattaa gattaatgtc
    20821 aataaaccgt tcgtagtgac caagatccaa gtcagtctct gcaccatcat cagtgacata
    20881 gacctcccca tgctgataag ggctcattgt cccaggatcg atattaatat aagggtcgaa
    20941 tttttgaatc gttaccttta ggccacgatt tttcaataaa cgtccaaggc tagccgctac
    21001 aatacctttt ccgattgatg agaccactcc gccagttaca aaaatgtact ttgtcataac
    21061 actcctttat ccttttgagt taagcctgac taactcgttt ttatttttaa aagatcgtcc
    21121 tactttagct agtaacgatt gggggctaag cttcccataa ggctaagcca tgagaccagt
    21181 aaccaaggct aagttattaa aacaaaaata gccccctatt aactagggag cttacctgac
    21241 ctcttaaaga ggtgcccgat taataatata aactataaga ggacatttgt caaatattac
    21301 tgttgctttt agaggctagc gatactcctg ctattcctcc tcttcctcat cttcttcgtc
    21361 ctcttcattg aggtcaacct cttcaaaatc gtcctctgga atgatttcat tgagctctga
    21421 atcgtaggac tctacttcag atttttcatc gtctggatct tcctcgtcat attcaatatc
    21481 agatgattca cgaacaaaat cctcatcctc tggatcatca gcgctatagt caatagcgtc
    21541 ctcatcaccg tccatgaagg cattgacacg tttcttcttg cgttttggtg cgccgtcttc
    21601 ttcatcttct agggtgatga tttcctcatc aatctcatca atagcatacc atgaacgtag
    21661 accccattta ttttcaccaa gtggaataaa gctaccatct gtattgagat cagtgtaaaa
    21721 aaatggtaaa gcatatcgaa tatcagcgtc agacttgcct aggtaatttt gaatctcatt
    21781 aaccaaatcg ctaaaataca tgtcattatc gcgaccacgc tcttctaaaa tagcacgagc
    21841 aacttcaatc atagaaagtt cgcttatttc ttgtcctgca aatacatcta atttcaaggc
    21901 agttctcctt attttatcat tctcccctat tttacgctaa aaataccgat tcgtcaaagc
    21961 ttttatcagg gaagaacagt attcttttta cccacttctc agccagcaag aacaaagcct
    22021 agcagcaacc agcttgattg ctcctaaacg cgataacaga agcatttcaa agagaagtgt
    22081 taactgtttg cctttaaacc atgaagcaac agcaaaacaa gaccaagtgc ttgcttagtc
    22141 ttgcttgtct atatcataac agcttatttt gcttttgctg agcttgtaat cacttctaca
    22201 gcttttttca taacaatgtc atgctttaac atatcagctg aaagcaatga gcgaacctgc
    22261 tcaactggca tgctatactc agctgcaagg tcgttaattt ctttttcaat ctcatcgtct
    22321 gaagcttcaa agccctctgc ctttgcgata gcctcaataa cgagattagt tttgacacgc
    22381 ttgtctgcct ctgcttcatg ctgcttgtga agatcttctt gacttgtgcc agttagctgg
    22441 aagtacatat caggtgaaat gccctgacgc tgcatgctag ccataaattc attaacggaa
    22501 cggtgaacct cgtcatgaac catttcctct ggtaattcca caatttcagc attctcaaca
    22561 gctaactcaa tagcagcacc ctctagagcg tcatcataag ctgcttcctt tgaagcctca
    22621 agctctttac gatacttagc ctttagctca tcaagtgttt caacttcctc gtcaatatcc
    22681 tttgcaagct catcgtcaag ctcaggtact tcttttgcct ttacctcatg aacagttgcc
    22741 acaaacttag cagccttacc tgcaagatct tcagcttgat aattttctgg gaaggttaca
    22801 ttaacctcaa cagtgtcacc agccttagcg ccaactagct gttcctcaaa gcctggaata
    22861 aattgtcctg agccaagctc aagtgagaaa ttgtctcctt tgccgccatc aaattcaact
    22921 ccatcaacag agcctacaaa atcaataaca actgtgtcac cttctactgc tgcttcttct
    22981 ttgacaacca gctcagcaag attgttgcgc tcgcgctcaa cctttgcgtc aacctcctca
    23041 tcagtaacct cttttgaagc ctcaacctca acagtaaggt ctttgtaatc accaagctta
    23101 acctctggtt ttgtgacaac ctctgcagta agtgtccatt cttgacactt ttccatagaa
    23161 accacatcaa tttttggctg tgcaacaaca tcaagctcaa gctctgcaac agcaccttca
    23221 taggctgctg gcagcacaat attcaaggcc tcctcataaa gaacctcttc accaaatctt
    23281 tgatcaaaaa caggacgagg catgtgaccc ttacggaagc ctggtgcatt taaatccttt
    23341 ttaattttat taaaagcttg atcaagagcg ggcttgattt tatcttgact aatggtaaat
    23401 gtaatcacgc cacgatttgt agctttgttc tcaaatgatg tagacattaa gtcatttctc
    23461 cttaaaataa tttagataca cctcattcta tcatattacc aagtgttttt aaagtttttt
    23521 atgcgtgaaa gtagggacag ggtttccaaa tatcagactc ttaactgaac cattaccaaa
    23581 aacctcatca gcttcaaaga aaaagagact ggaacaaaag tctgcctcca aaataaaaca
    23641 aacgaacaag acttgttttc tgagatccca aaaactagtc ttgttcgctt tttaattatt
    23701 tagactgggt aataaaatac attagctaag actttttaac atgcaactct ttttgtccca
    23761 gagtccaaac agtccttaat ctgtaagcca gatagttacg ctggaagtag gacagctact
    23821 gatttcttag ctagatgacc ggtaatgttg tgattggaaa catgataaac tgtgccagtc
    23881 actgcgtctt tgtagtcacc gtcagctagg gttgttgtag aagaaaagtc tttatcaacg
    23941 atggttaggt tggtgataac agcacccttt tgaccgcgtt caatcatgac tagaccttgg
    24001 tccataccag gattgcgaat atattctgat tgaccattca tcctattgcg gaattgatta
    24061 atcgcaacaa tggttggatc cttaaacaag tcactgccgg catcaccaat ttggctttct
    24121 ccagggaagc gtccattttg gccgccaccg ccacgaggac gtgaaaagaa gagcggtgct
    24181 ccctcattac gagcagcaat aattccccag ccaagcttaa tgtcctcatc tgttagcttg
    24241 gtagactctt catcatcgtt agcataggta tcatgagatt ctacccaagt gactaacttg
    24301 tcctctgaaa cgccatgcac ttggaaattc accaaatccc aatctttcac atagccttga
    24361 cctagcactt tacggattag cttaccatag tttgacgctg tcactcccat gatattgcca
    24421 tagcctgctt cgttgcaagc atcaccctgt aaaatttctc catattggaa tttagcacca
    24481 ttgttaagaa taaccttcca gaaatcgctg ttatgctcac ctggtaattc gatatgcttt
    24541 gcagcatcat acctaaagcc atctgctcca tcagctactg ctcgttttag ataattcagc
    24601 atgtattctt ggacagctcg attttgcgtg ttgaaatcat aaagtcctag caaggatttt
    24661 tgggttattt gataacgatc gttgaagttg acgattttgt catttccatg tgtccagtta
    24721 tctatggctg tgatcttagg gctaactgcc ttaatctcag aggttgtatg attcaaaaca
    24781 gcatcaacaa taatattgat cccatattta tcagcctcct gagccattgc cttaaattcc
    24841 tcttctgttc ctaattggta gttcccgata gtatagtctg ttggctgata atggtaatac
    24901 cagtttttca agtccttact accgccagct ccttcaatga cagcattaat aggtgaggtt
    24961 tgaatactag tgtagccagc ttccttaatg gcactcatgt tttctttgat ggtgttaaag
    25021 gaccagcacc aagcatgtaa aatagctccg tccttcatgg ctaccggttg attatcggac
    25081 tgcacctcct gagcactagc aaggttagct ggggctagag gagccaagcc tgaaagtacc
    25141 aagccaaggg tcaagctggt cactgataga gctttgagaa atctttttgt cttatgtgtt
    25201 accatatgta aactccgttc tttctgcgaa atcgctttcg ttggcgctta aaaaaataag
    25261 atgattctct gtactgtttg caaacaaaaa taggacctat gagagaagta taacatataa
    25321 atttcggtat gcataccatt tttagcaaaa aattagtgat ttttttaatt tttatttcct
    25381 ttgctaaagc ctctaaaacc aatcaaaata atgttgcata agtatttgcc ttttatttat
    25441 ctcataatca gactcattcg ctctaatctt ttgcacatgt taatgtcatt tatttgcaga
    25501 cctacgcaac caattgcaca gagctttgtt tccttcgtca gaaaaacctc aataaaacat
    25561 aaacaagaag ccattactct tcttgataat gtttggtgat ctattttcaa ccaggacttt
    25621 ttttggtaaa ctagctacga tagaaaggag ttgccatgac gtttatatta acatacttta
    25681 atcagctaca cctagaaaat atcatggtgc ttgtgttttc taaattagtg tcaatcacct
    25741 tattattgat tttctttgtg atcttcaaaa aaatcacgac agctttattt gaaaaggcaa
    25801 tcgccaagtc attttcctat tcaagacaaa ctgaagcaag gaaaaaaacc ttatccaagc
    25861 tccttcacaa caccctaaat tatgttttct attttcttct catctattgg attttgagcc
    25921 tacttggtat tccagtatct agtcttttag caggagcagg aattgctggt gttgctattg
    25981 ggcttggggc tcaaggcttc ttgtctgatg tggtcaatgg cttttttatt ctgtttgaaa
    26041 atcaatttga agtaggagac accgtcacca ttgcaggcat tgaaggaacc atctccagcg
    26101 ttggtattcg aaccactcag gtgcgaggct ttgatggcac actacatttt attcccaacc
    26161 gcaatattac agttgttagc aacaaatcac gcggcaatat gagagctttg atcgatattc
    26221 cactttattc ctcaaccgat ctagagcatg tgacccaaat catcaaggct gtcaataagc
    26281 gagaggtgcc aaatttccca caaattgtcg gacagcccaa cattctagga ccacaaacca
    26341 atcccaacgg acaattcacc tttcgcgtta gcatttttac tgaaaatggg cagcaattta
    26401 cgatttacta tagcttttat aagctctatc aagaggcctt actaagggag ggtatcaagc
    26461 taccaactgc atctgccata tcacccttag cctagcagta aaaaccattg ctttcttagc
    26521 atacaaaagc cctatcccgc agccaggtca tcagacttag actgctagat agggctattt
    26581 cttttggctc ttatttccga ataggatcag gctgatacct ggctcttaca ccaccaatta
    26641 atttgggccg acttgctaag gcagtcacat gagcaccacc aagctctcgc tgaataggca
    26701 caagcggcac ctgtacacgc ttaacatgca taccaattga ggtatctcca atgtcaaggc
    26761 ctgcatgagc agcaatggct tcaacctcaa ctggctgctt catgtatttg aaggctgcta
    26821 attgaccact tcctccagca tgcaagctag gcagcacatt gactatttct agccgatatt
    26881 cttcagcaac actttcttct aataccaagg cacgattaat gtgctcacac ccctgaaccg
    26941 ctaaatgaat ccctctgaac gacaattcct ccaatataag cttcacaata acctcgccca
    27001 cctctaagct agaatgctgg ccaatacgac caccaagtac ctcgctagag gacagcccta
    27061 agacaaacag ttgccctttt ttgatagcac tacgctccac aatatcaagc aagatagagc
    27121 gtgcttcttc tctcaatact tttaaattca ttgaatcacc tgcttaatca tctgacactt
    27181 tgaccagctg ttttttgacc cctaaataca gcagatagcc tacacctatg ccaagggtat
    27241 tttgagcagc attccccgaa atttctgaaa tagcagcgcc cataccatac attggaatag
    27301 ctgcaagaaa atacagacca accattatca cagaagcaag gcccacgcca agaaagcgat
    27361 gcctgccagg caagcctgct aagtagccct gagccccatg agcaacaaga ctaatcagca
    27421 tccaattggg gtaacctgag atcaaatcaa gcaaaaaagc tgataagccc ccaacaagca
    27481 taccctcctt tttcccaaga gaaaaggcag tcacatacac ccctgcatct aaaagactta
    27541 aaaaacctgt cggcgtggca atactcacaa acctgcccag gacaactgtc agggcagtca
    27601 agatagacac aagagctagc tctcttgtct gtttcatatt tatcataaga caactccata
    27661 atcatttgac tgttgaatgg cttcaaaaac aaggtcttta gcctgctcaa cagccctaag
    27721 cggtgaatat cccttagcta aataagcagc aattgcagct gcaaagctac agccagcccc
    27781 actgttttgt ttggccaaga ctggcttttc taaaaagcac agggtttttg cgtcataaaa
    27841 tagatctagg gcaactcgtt gatcaaaacg attcccaccc ttgatcacaa ccctcttagc
    27901 ccccatctca taaagctttt ttgccgcttc taccatttgc tccctgctat taatagcaag
    27961 ccctgccaag cgttctgctt ctcttaggtt gggagtaatc actgctgtta agggaaaaag
    28021 agagcgcaaa gcctgtgtca tttccacaac tgtctgatct tgattttcct taaatactaa
    28081 aacaggatct aaaacaacag ggatatcctt ttttagctct aaaaacaggg ccacctgctc
    28141 tgctatttca ggtcttggca aaagaccaac tttgattgcc tgaaaaggaa tagctgctaa
    28201 gctagacaac tgctttgcca gcaaatcagt cgcaacaggg tgaatgctga aacctttagc
    28261 atcacagctt gttaagcagg tgatagctaa aaatgcaaag ctatcgagct gatgaagcac
    28321 tgccaaatca gcctgcaaac caccaccgct gaatatatca ctcccagcaa tcgttaatac
    28381 cttattcttc ataaatgatt tccttcaaat aaagaccatt accagccgct gtcggtccag
    28441 ctagctgccg attcttactc tctaaaacga gcctgatttg ttcaatgggc aaccgaccat
    28501 tgccgatctt aagcaaggtc ccaaccatat ttctaacctg cttataaaga aagccattcc
    28561 ctgaaaacgt aaaaacaaga aaaccagttt tagggtcctg agtgagggta gctgctgtaa
    28621 tggtacgaac cttattttta acagaggttc ccgcagctgt aaagcctgta aaatcatgcg
    28681 tcccaaccaa atccttaatc gcagcctgca ttttcgcaat atctaaggga taagggtaat
    28741 gggtcgcata atggcgcatc ataggatttt taggacgacc aatatccact aagaattcat
    28801 aggttttgaa atgcttatgg tagcgagcgt gaaaatcatc tgctgcaatc tccagactga
    28861 tcacatcaat atcatctggt gtctgggtat caagtgcaaa gcgaagcttt tcagggtctc
    28921 ttttttgctc caaatcaaag tgaatcactt gaccataagc atgcacacct gcatctgttc
    28981 taccagctcc atgaatctgt atcccttgac cacctgtcaa tttttgcagg gtcttttcaa
    29041 tctcttcttg taccgtacgt gcctgacttt gtctctgaaa accagaaaat aaggtcccat
    29101 cgtaggaaat aattgcttta tatcttgtca tgctattatt ctaccatttc ttccagccat
    29161 cagaaaagag catttacggc ttttgtcccc atacagtttt cgattagctt tgataatcaa
    29221 gcttgatttg acgccaacag gcaaaaaaag gctactgaca aggactagct tttctgctat
    29281 aatttctcta atattcaata agtagactgg agagcaaatg aaggtaacaa aatttggcgg
    29341 cagctcctta gcatctgccc agcagttaga aaaggtcttg gctattatca aggacgatcc
    29401 tgagcgtaaa atcatcgttg tctccgcacc aggcaaacga tcccctacag acacaaaggt
    29461 gactgatgca ctcattgctt attacaaagc ctacgtctca gaccgtcatt atcacaagca
    29521 tttggaatgg attatcaatc gttaccaaca aatctgtaat gacctaactc tagatagcaa
    29581 aatcatcacc caaattaaag cttccttaga gcaattggca cggcttccaa aagaacataa
    29641 tccctattta tacgatacct ttcttgcggc cggtgaggac aataatgcta agctagtagc
    29701 tgcctacctc aaggcaaatg gcttaactgc aagctatctc caccccaaag atgcaggtct
    29761 aatcgtaagc agtgagccac agcatgcacg tcttcttcca atcagttacg ataagctaga
    29821 ggccttaaag gatcatgatg acattcttgt tattcctgga ttctttggtg tgacaaatga
    29881 aaaccagatt tgtaccttct cacgtggtgg ctctgatatt accggctcca ttattgcagc
    29941 aggagtcaca gctgacagct atgaaaattt tacagatgtc aatggcatct ttgctgccca
    30001 ccctggtgtt gttaagcagc cacagacgat cactgaatta acctacagag aaatgcgcga
    30061 gttagcctat gctggctttt ctgtcctcca tgatgaagca ttaatccctg cttaccgagg
    30121 gaaaatccca atcgtcatca aaaacactaa caatcccagc cacccaggta caacaattgt
    30181 tcttgagcac cagaggaaat ccaatcccgt tgtcggtata tcaggtgatg atcactttgt
    30241 cagcattaac ctatctaaat acctcatgaa cagagaaatt ggatttgggc gcaagctcct
    30301 tcagatatta gaggacctca atatcagatg ggagcacatg cctacaggta ttgatgacct
    30361 atcaattgta cttagagaaa gagaattgac ccccatcaaa gaagaagaaa tccttcgcag
    30421 acttgtccag caattagagg ttgatgaggt gtccatcacc aggaaccttt ctattatcat
    30481 gatagtcggt gaaaacatga aaagtcatat tggtgtcaca tctgccgcaa caaaggctct
    30541 atctgaacat catatcaata ttgctatgat ttcccaaggc tcaagtgagg tatctgtcat
    30601 gtttgtcatc aatagcaccg atgaaaaaaa ggccattaga gccttatatc aaaccttttt
    30661 tagccctgat cgacccctgt aaagctccat ataacatctc ttgttaacac caagcttcaa
    30721 aaacagctca caagctagac agtactccta gcctatgagc tgttttgatg atctaaaact
    30781 atcaagatta agcatcggta gtaacgactt aatatgctca cagctatcat aaactctagc
    30841 tttaccttat tgaggaaaag aaaaccagtt ttcacctcag ctaagattaa caacaagcga
    30901 ttaagcactt gctaaaaaca gatagacttc aaaagtgaga catatgtata atttctacca
    30961 gatctaaata aatatagcag cagagcaccg agtttaataa gccatttctg acatgataaa
    31021 ctcgccaagc tctccacaga tcaagatttg ccttatcaat tgatacaaca gccagcattc
    31081 tcaaagatgc acaagatcca tcacagtcta gccatctccc tgcacagtaa gcctttcaat
    31141 ctcgttccgg taaccccttt tatttctcac cagtaaagtc ctgaaagtaa ggtcctatct
    31201 tgcgaagcaa ggcccgtctc ccctcaaacc gctctcccct gatcaaagcc cgaaactgcg
    31261 acagctcacc ctctgtcaat cgctcctcaa cctccttcac aatcaactga taagccacat
    31321 aatcatctac tcccaaacca cctgctggta tcgcatggcc taccgaccca atctcctcat
    31381 aagccatctt atgaaaccga cgcttctgac tctcctgctg ccgcaacacg tccttcaaat
    31441 aagaggaaaa cttggtctta aaataacgat atagcttctc ctcatcctct atcaattctg
    31501 gataagtgac caataaccga tacaagatca accgcccctc ctgtaaccaa tcatctagct
    31561 cccacagctg aatataataa tgctgtctta gcttcataat aataggcttg atcttatcaa
    31621 acaacctcac taaatcatca gtcattatac tttctccttt tcatgcttag tagccttatt
    31681 ataaggagac aaacaaaaaa acaacaggac agaaatgtcc tgttgccttg ctatgcaccc
    31741 tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg tactctatcc agttgagcta
    31801 agggtgcttt tcttaactat tactatccta ccatactatc ccctaaaaag caaggctcta
    31861 taccatctgg aataggtaag tccactgtgg aaatcataga gctttttgag tacacaaaaa
    31921 agagagcacc aaactgatcc tctctaaatg tccgttgtta gtcaacccac tatagttgac
    31981 atagagccaa actccgccag taggactcga acctacgaca tcatgattaa cagtcatgcg
    32041 ctactaccaa ctgagctatg g
//
LOCUS       DARYYD010000023        31750 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.023, whole genome shotgun sequence.
ACCESSION   DARYYD010000023 DARYYD010000000
VERSION     DARYYD010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31750
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.023"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..1435)
                     /locus_tag="TV188_000965"
     CDS             complement(<1..1435)
                     /locus_tag="TV188_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEL1534336.1"
                     /translation="MKFTIVRNYDKLSRTILRLESDKMTIFRKKRQAINKTEMNRHLK
                     MLDLIFLGLGSMVGTGIFTITGIGAANYAGPALTISIILSAIAISILALFYAEFASRI
                     PANGGAYSYVYATLGEFPAWIVGWYIIMEFLTAISSVAVGWGSYLKGLLANYGLQLPN
                     ALNGTFDPQKGTYVDLLPVLVMLLVTAIVLMNSKAALRFNSFLVLLKFSALALFVIVG
                     LFFIDVANWSHFAPYGFGQIYGGKSGIFAGASVMFFAFLGFESISMTVDEVKEPQKTI
                     PRGIVLSLTIVTILYVIVTMVLTGIVHYTKLDVPDAVAFALRSIGLYWAADYVSIVAI
                     LTLITVCISMTYALARTVYSISRDGLLPRALCQITEKTRIPRNATLVVGALSMICAGI
                     FPLASLAEFVNICTLAYLVIMSFAIIKLRKNAGEPQRGEFKTPFVPLLPILAIIICVT
                     FMSQYMVFTWIAFGISTILGIVVYACYG"
     gene            complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TV188_000966"
     CDS             complement(1525..3495)
                     /gene="ftsH"
                     /locus_tag="TV188_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEL1534337.1"
                     /translation="MKNNKNNGFVKNSFIYILMIVIVVAGFQYYLRGTSTQSQQISYS
                     KLIKHLKAGDIKSLSYQPSGSIVEVKGKYEKPQKVSIDTGLSFLGNSAATEVTEFTAL
                     ILPSDSVLKEMTSVADKNGTDITVKQESSSGAWITFLMSFLPIVIFAAFMMMIMNQGG
                     GARGAMSFGKNKARSQAKGDVKVRFTDVAGAEEEKQELVEVVDFLKNPKKYKALGARI
                     PAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAKK
                     AERAIIFIDEIDAVGRRRGAGMGGGNDEREQTLNQLLIEMDGFEGNESIIVIAATNRS
                     DVLDPALLRPGRFDRKVLVGRPDVKGREAILRVHAKNKPLAEDVNLKVVAQQTPGFVG
                     ADLENVLNEAALVAARRNKTKIDASDIDEAEDRVIAGPSKKDRSISQREREMVAYHEA
                     GHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKDDLKEQLAGLMGGRV
                     AEEIIFNAQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMMPGQLSPEKS
                     YSAQTAQMIDDEVRDLLNEARNKAADIINDHRETHKLIAEALLKYETLDAAQIKSIYE
                     TGKMPNDPENDEAEVHALSYDEIKDKMTEAKE"
     gene            complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TV188_000967"
     CDS             complement(3517..4059)
                     /gene="hpt"
                     /locus_tag="TV188_000967"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012961310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEL1534338.1"
                     /translation="MLEQDIQKILYSENDIIQRTKELGEQLTKDYHGKNPLMVGVLKG
                     SVPFMAELMKHIDTHVEIDFMVVSSYNGGTTSSGEVKILKDVDTNIEGRDVIFVEDII
                     DTGRTLKYLRDMFKYRKANSVKIITLFDKPEGRVVDIEADYVCYNVPNEFIVGFGLDY
                     AENYRNLPYVGVLKEEVYSK"
     gene            complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TV188_000968"
     CDS             complement(4064..5347)
                     /gene="tilS"
                     /locus_tag="TV188_000968"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEL1534339.1"
                     /translation="MTYQHIYNIIKKKAYFDAHQAVLIAVSGGVDSMNLLHFLHAFQA
                     KLQIRIGIAHVNHKQRPESDDEEAYLRSWAKKHAIPIYVAYFQGAFSENAARHLRYQF
                     FEEIMQQEHYSALVTAHHADDQAETILMRLIRGSRLRHLAGIREVQPFANGQLIRPFL
                     TVSKAELPNPFHFEDHSNDSMAYFRNRVRHHYLPDFKRENPQATQSLIDLSAESRLLL
                     QAFDDLTKGLEFHRLNCFLAQSAAVQFFLLQHYLETFPQLAIKKSQFDDLLHIIRRQK
                     QGIYPIKNTYCLLIEKESFAIKKIIPKTDLNREFKMVSYGDSLNYRGYRFVFSGSLTD
                     KGHDIAIPLYSLSPVTLRHRQAGDRLFLGEFSKKLRRLFIDGKFTSEQRQNAIVGEQA
                     GVIIFVLVGDETYLRKASKHDIMLAKLYIDKLEKR"
     gene            complement(5344..6630)
                     /locus_tag="TV188_000969"
     CDS             complement(5344..6630)
                     /locus_tag="TV188_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HEL1534340.1"
                     /translation="MKKLLAAMLMTFFVTPLTVISTEKIPVFSEATRYHLSQDIVSST
                     LYYSRIPTNPNVFEETVAYRDPELSVPKTMIAPDNRIVIKDVLLNKAAIPVFRLADDT
                     YLEASRQIVYEDIMFEQTAVDLDFWTQKKMTIYAEPYVLGVKTIASDSEPGRKVHASK
                     MAQTEHGTYYFIDHKGWVNQKELSPTDNRMLKVQEMLLQKYNKENYSIFVKQLNTQAS
                     AGINADKQMYAASISKLATLYSVQKKLKSGSLSEGKSLKYIDEVNHFYGDYDPTGSGK
                     ISKTADKKDYNVMELLKAVAQQSDNVATNILGYYLCNQYNQAFQSEIRALAGVDWDME
                     KRLLSSHAAANLMEAIYYQKGQIISYLSQTAFDDQRISKNISVPVAHKIGDAYDYKHD
                     VAIVYGDNPFILSVFTDKASYDDITAIADDVYSILK"
     gene            complement(6772..7143)
                     /locus_tag="TV188_000970"
     CDS             complement(6772..7143)
                     /locus_tag="TV188_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002987674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEL1534341.1"
                     /translation="MKKPSIVQLNNHYINEENIKKRFEEEEIQKRNRFMGWILVSMMF
                     LFILPTYNLVKGYVSLKKQGQQIITLEKEYRELEKKTKSEKQLAEQLKNDDFVKKYAR
                     AKYYLSREGEVIYPTPGLLPK"
     gene            complement(7130..7402)
                     /locus_tag="TV188_000971"
     CDS             complement(7130..7402)
                     /locus_tag="TV188_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEL1534342.1"
                     /translation="MRLDKYLKVSRLIKRRSVAKEVADKGRIKVNGILAKSSTDLKLN
                     DQVEIRFGNKLLTVRVLDMKDSTKKEDAAKMYDIISETRISSDEEA"
     gene            complement(7433..8944)
                     /locus_tag="TV188_000972"
     CDS             complement(7433..8944)
                     /locus_tag="TV188_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEL1534343.1"
                     /translation="MRLNLEKLPHKTKQSSLLIVISGFMSKLLAASYRIPYQNLVGDR
                     GFYAYQQIYPLLGIISALGLTALPNVIASMAQKKKQLQLAALFKLQCYTSFLLSGILV
                     LSHKALASWMGAQQLAPSIVITAMVLLIVPFISFYRGLAQADMNMAPTALSQVLEQII
                     RVAIIIVAALCYRVLGWTVYLTANVAAFGNLVASLVILAYLKRHSAYSLKSFLSGDTV
                     AIRDLTSLGLPTLVFLLFSIYLLVFQLIDSLLVKNILVSSGLSEITAEMTKGVYDRGQ
                     PLLQFGLIFSTALFTAYLPNLTVLFHIKRESYREQSQCFFEFIFYFSLTLTVGFISIL
                     HLMNRALFEDNKGWLALVVYLMIIAVSSMIQFFHQKCFIEDHIKQSLLILLFGFLLKL
                     GLTPILTYYYAIVGSSLSTLIPLLVVLLLYAVLADIDFKAIVNAKYGLALVIMLMCVL
                     TSQYCLPLSGRLGALISLLVSSAVGLSSFLIACKKLGVFKEKLWSFLPFVKEK"
     gene            complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TV188_000973"
     CDS             complement(8913..12407)
                     /gene="mfd"
                     /locus_tag="TV188_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEL1534344.1"
                     /translation="MDILELFNQNKSIQTWQCDVTSLKRQLVMGLSGSSKAAAIASAY
                     LSFQGKLVVVTSTQNDMEKLAGDLSALLDEGSIFQFFADDTAAAEFIFSSMDKTISRI
                     EALAFLSNPEARGILVISLAGLRILLPSPKTFQQGQIDLAVGVDTDLDNVVKKLVKIG
                     YQRVAQVLSPGEFSRRGDILDVYEVTQDLPVRIEFFGDEIDGIRSFDIESQKSLQKKD
                     STSIKPASDMIFEPEDFDRASHNLEKQLQLAKAEHKGYLEELLTVTKEGLKHKDIRKF
                     QSLFYDNEWTILDYLPKGTPVFFDDFQKLVDRNAKFDLELAHLLTDDLQQGKSLPFLH
                     YFADNYRELRHYKPATFFSNFHKGLGNIKFDKVYSLTQYAMQEFFNQFPLLIDEIKRY
                     QKSGATVLLQVESHQAYERLAKSLEAYQCQLPLVSADAIVLHQAQIIIGHLAGGFYFA
                     DEKLVLITEHEIYHKRLKRRARRTNMSNAERLKDYNELSKGDYVVHSVHGIGRFLGIE
                     TINIQGVHRDYVTIQYQQSDRISLPVDQLESLSKYVSADGKEPKINKLNDGRFQKAKQ
                     RVKKQVEDIADDLLKLYAERSQQKGFQFSPDDELQRAFEEDFAFVETDDQVRSIKEVK
                     KDMESVRPMDRLLVGDVGFGKTEVAMRAAFKAIGDHKQVAILVPTTVLAQQHYENFRE
                     RFENYPVEIAVLSRFRSKKEQSESLERLKKGQVDIIIGTHRLLSKDVIFSDLGLIVID
                     EEQRFGVKHKETLKELKTKVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPVQ
                     TYVLENNPGLIREAIIREMDRGGQVFYVYNKVDTVDKKVAELQELVPEASIGFVHGQM
                     SDIQLENTLMDFINGDYDVLVATTIIETGVDISNVNTLFIENADHMGLSTLYQLRGRV
                     GRSNRIAYAYLMYKPDKVLTEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNILGA
                     SQSGFIDSVGFDMYSQLLEQAIASKQGRALTRQKGNAEINLHIDAYLPSDYIKDERQK
                     IDIYKRIREIDSRAAYSDLQDEIMDRFGDYPDQVAYLLEIGLLKYYLDTAFAELVEKR
                     DHQVMVRFEVASLQYYLTQDYFEALSKTSLKARISEHQGKIEIIFDVRRQKDHVILEE
                     LILFGETLGEIKSRKASS"
     gene            complement(12410..12979)
                     /locus_tag="TV188_000974"
     CDS             complement(12410..12979)
                     /locus_tag="TV188_000974"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEL1534345.1"
                     /translation="MVKMIVGLGNPGSKHQQTKHNVGFMAVDRLVKDLDVSFTEDKTF
                     KALIGSTFINQEKIYFVKPTTFMNNSGLAVRALLTYYNISTKDLMVIYDDLDMAVGKI
                     RLRQKGSAGGHNGIKSIIAHIGTQEFDRVKIGIGRPSHGMSVINHVLGKFDTDDMITI
                     NIALDKVDKAINYYLQEKSIEKTMQQFNG"
     gene            complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TV188_000975"
     CDS             complement(13138..14253)
                     /gene="ychF"
                     /locus_tag="TV188_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEL1534346.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTELITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESINKRYARVEKMARTQKD
                     KDSVAEFAVLEKIKPVLEEGKSARTISFTDDEQKIVRQLFLLTTKPVLYVANVDEDKV
                     AIPDAIDYVKQIRDFAATENAEVVVISARAEEEISELDDEDRSEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGIKAPQAAGIIHSDFERGFIRAVTMSYDD
                     LIKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(14337..14702)
                     /locus_tag="TV188_000976"
     CDS             complement(14337..14702)
                     /locus_tag="TV188_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1534347.1"
                     /translation="MMTKFAEQLKKYRLEKQLSQDALAEKLFISRQAISKWENGDATP
                     DLENLVTLAAVLEVTLDELVTGKEPAIKVIKKTEKPMNVWEFLTEESKRPMRKGDLLM
                     LLLVVIVLLGVYFIVIHFS"
     gene            complement(14823..15020)
                     /locus_tag="TV188_000977"
     CDS             complement(14823..15020)
                     /locus_tag="TV188_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003048966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEL1534348.1"
                     /translation="MYQVGSLIEMKKPHACVIKETGKKANQWKITRVGADIKLQCTNC
                     NHVIMLSRHDFERKMKKVLQP"
     gene            complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TV188_000978"
     CDS             complement(15098..16234)
                     /gene="dnaN"
                     /locus_tag="TV188_000978"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEL1534349.1"
                     /translation="MIQFSINRALFIQALTATKRAISSKNAIPILSTIKIEVNPSDIT
                     LTGSNGQISIENTIPVSNENAGLLITSTGAVLLEASFFINIISSLPDVSLEFKEIEQH
                     QVVLTSGKSEITLKGKDVSQYPRLQEVSTENPLILNTRLLKSIIAETAFAASMQESRP
                     ILTGVHITLSQHKNFKAVATDSHRMSQRLITLEKTSADFDVVIPSKSLREFSAVFTDD
                     IETVEVFFSASQMLFRSDYISFYTRLLEGNYPDTDRLLMKQFETEAVFNTQSLRHAME
                     RAFLISNATQNGTVKLEIEANRISAHVNSPEVGKVNEDLDVVSQAGNDLTISFNPTYL
                     IEALKAIKSETVKIHFLSPVRPFTLTPGDDEESFIQLITPVRTN"
     gene            complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TV188_000979"
     CDS             complement(16391..17743)
                     /gene="dnaA"
                     /locus_tag="TV188_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012657571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEL1534350.1"
                     /translation="MTENEQIFWNRVLELAQSQLKQATYEFFVHDARLIKVDNHVATI
                     FLDQMKELFWEKNLKDVILTAGFEVYNAQIAVDYVYEDDLMIEQQHQGQQGYTEQAFQ
                     QLPAVQSDLNPKYSFDNFIQGDENRWAVAASIAVANTPGTTYNPLFIWGGPGLGKTHL
                     LNAIGNSVLLENPNARIKYITAENFINEFVVHIRLDTMDELKEKFRNLDLLLIDDIQS
                     LAKKTLSGTQEEFFNTFNALHNNNKQIVLTSDRTPDHLNDLEDRLVTRFKWGLTVNIT
                     PPDFETRVAILTNKIQEYNFIFPQDTIEYLAGQFDSNVRDLEGALKDISLVANFKQID
                     TITVDIAAEAIRARKQDGPKMTVIPIEEIQAQVGKFYGVTVKEIKATKRTQDIVLARQ
                     VAMFLAREMTDNSLPKIGKEFGGRDHSTVLHAYNKIKNMIGQDESLRIEIETIKNKIK
                     "
     gene            complement(17976..18749)
                     /locus_tag="TV188_000980"
     CDS             complement(17976..18749)
                     /locus_tag="TV188_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEL1534351.1"
                     /translation="MTEILMHIPIEDIVANPYQPRLQFNQKELEELAHSIQANGLIQP
                     IIVRKSDVFGYELVAGERRFKAAKLAGLQKIPAIVKEISTLESMQQAIVENLQRSNLN
                     AIEEAKAYQLLIDKNKMTHEDIATYMGKSRPYISNTIRLLQLPDVIRQAIEDGTISAG
                     HARALLSLSTPKEQELYFHNILDQGLSVRQIEQLVKTKHPPKKRNKHKTIFVKSLEKE
                     LSKSLGLPVALSLQKNDSGQLQLSFSNQEELNRIINKLL"
     gene            complement(18869..20092)
                     /locus_tag="TV188_000981"
     CDS             complement(18869..20092)
                     /locus_tag="TV188_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HEL1534352.1"
                     /translation="MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGA
                     TTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAASPAISNPYINLFGEENDTSAVQK
                     EDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
                     DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVT
                     SRNEAGETISTNAIQTDAAINPGNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGI
                     GFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQLNIPTSVTSGVVVA
                     STQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKV
                     DIKLTKTTKDLTKKQ"
     gene            20302..20781
                     /gene="rlmH"
                     /locus_tag="TV188_000982"
     CDS             20302..20781
                     /gene="rlmH"
                     /locus_tag="TV188_000982"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEL1534353.1"
                     /translation="MKIKLICVGKLKEAYLRDGIAEYQKRLSRFCQCDIIELADEKTP
                     DKASHAEKQQIMAKEADRIKKKLGQRDFVIALAIEGKQLASEQFSHLLSEVTVKGYSD
                     IAFVIGGSLGLDQSIKNRANLLMSFGLLTLPHQLMRLVLIEQVYRAFMIQQGSPYHK"
     gene            complement(21081..21154)
                     /locus_tag="TV188_000983"
     tRNA            complement(21081..21154)
                     /locus_tag="TV188_000983"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21118..21120),aa:Arg,seq:tct)
     gene            21435..21506
                     /locus_tag="TV188_000984"
     tRNA            21435..21506
                     /locus_tag="TV188_000984"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21468..21470,aa:Glu,seq:ttc)
     gene            21539..21612
                     /locus_tag="TV188_000985"
     tRNA            21539..21612
                     /locus_tag="TV188_000985"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21573..21575,aa:Asn,seq:gtt)
     gene            complement(21873..24458)
                     /locus_tag="TV188_000986"
     CDS             complement(21873..24458)
                     /locus_tag="TV188_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEL1534354.1"
                     /translation="MTKPKAWSLVYDIASFLLPFLIMFFVLLSMGISYGSEKTILASD
                     GFHQYVIFAQALRNILHGADSIFYTFTSGLGVNFFALASYYLGSLLSPLVYFFNLQSM
                     PDAIYLLTLIKFGLIGLAAYFSFHRIYPKIKPFLVLTLSVSYSLMSFLTSQLELNNWL
                     DVFILLPIVLLGLYRLITQTKPLLYYSSLSLLFIQHYYFGYMVAIFIFLLFLVNLISL
                     DTWKRRLRACLSFTSVSILSALTSAFILIPAYLDLTAYGETLSPINQIIIKPIGAFDL
                     LAKLSLGAYDTTKFNAIPMIFIGLLPSLLSIVFFTLKSISWRLRLGYGLLLGLIMASF
                     YLQPLDLFWQGMHGPNMFLHRYSWSFSIIIIILACEALSRQKDITNTRIIFAFILLSC
                     LLTLPYLTMDQYSFLQPSLLILSLAFLAAYLILLLSMQKTSVPMPFLIFFTLLFSCLE
                     TSLNTYYQLNGIHHEWVFPSRKGYSRALQDIDRLVKKTADSNDQFFRLEQLLPQTGND
                     SMKYSYNGISQFSSIRNRHSSSLLDRLGYQSAGTNLNLRYQNNTLIMDSLLGIKYNLS
                     YHQLHKFGFSRIASSHHTTLYQNHYSSNLAILTDNIYKDVKLTVNTLDNQTKLLNQLS
                     GKRLTYFQLEPSKLISNAQVFNGRISGEAAENTSTTIVHYQVTVPNHRQLYLSLPNIS
                     FSNHNATAVRIRIDDQTYEYTTDNAFSFFDLGYFEKGRTLTLAIMFPKNKNISFATPH
                     FYSLNSDNYLAAMNAINQKEVTTYTRSNQVISHYKAKSEGSMIFTLPYDKGWTARLNG
                     RPVALKKAQGGFIRIDVPKGSGKLVLTFVPNGFTLGLLLSFIGILLYSFLHYYLLRQT
                     AKLKA"
     gene            complement(24581..26200)
                     /locus_tag="TV188_000987"
     CDS             complement(24581..26200)
                     /locus_tag="TV188_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1534355.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTAGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEEERAIDVVIMGNEQLYSIMKEKDAI
                     YMKPDFSEEDGVRAAELEGSFAELGGWEAESEASQLLQNLNIPEELHYQSMSELTNGD
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSISWLEDFLIDFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLFVGNYDFWKQSSELAARLQADRNAKAEEKIKELQEFVARFSANA
                     SKSKQATSRKKMLDKIELEEIIPSSRKYPFINFKAEREMGNDFVTVENLSVTVDGDKI
                     LDNISFILRPGDKTAIIGQNDIQTTALMRALADDIDYEGTIKWGVTTSRSYLPKDNSR
                     DFASDESILEWLRQFAAKGEDDDTFLRGFLGRMLFSGDEVKKSVNVLSGGEKVRVMLS
                     KLMLLKSNVLLLDDPTNHLDLESISSLNDGIKDFKESVIFTSHDHEFIQTIANHIVVI
                     SKNGVIDRIDETYDEFLENKDVQAKVAELWK"
     gene            complement(26280..27152)
                     /locus_tag="TV188_000988"
     CDS             complement(26280..27152)
                     /locus_tag="TV188_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEL1534356.1"
                     /translation="MKKRVMDLLFVTIGSFITAIGFNTMFVDNNIASGGMVGISVVIK
                     ALFGISPSLFLMLSNIPLLILCYFFLGKQNLIKTLYGSWIYPIAIRLTSQLPTLTHNQ
                     LLAAIFGGIICGIGLGMVFWGNSSTGGTGILTQILHKYSPLSLGVAMTIVDGISVLMG
                     FIALSADDVMYSTIGLLVIGYVISVMENGFDSSKNVMIISKEYQAIKAYITGVMDRGV
                     SKIPIRGGYTTSDKIMLMAIVSGYELPALQEKILEIDDTAFIVVMPAAQVMGRGFSLT
                     KHYKLEDKDVLLPM"
     misc_binding    27274..27513
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            27569..28591
                     /gene="trpS"
                     /locus_tag="TV188_000989"
     CDS             27569..28591
                     /gene="trpS"
                     /locus_tag="TV188_000989"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEL1534357.1"
                     /translation="MTKPVILTGDRPTGKLHLGHYVGSLKNRVSLQNENKYKMFVFLA
                     DQQALTDHAKESEMIRESIFNVALDYLSVGLDPSKSTIFIQSQVPELAELTMYYMNLV
                     SLARLERNPTVKTEIAQKGFGESIPAGFLVYPISQAADITAFKANVVPVGNDQRPMIE
                     QTREIVRSFNHTYKTACLIEPEGLYPENEKAGRLPGLDGNAKMSKSLGNGIYLSDDAD
                     TVRQKVMSMYTDPNHIRIEDPGQLEGNMVFHYLDIFGQKEDKADIEAMKEHYQRGGLG
                     DVKTKRYLLDILERELAPIRQRRLEYAKDKGEVFRMLEAGSQKAQAVAAQTLSEVKVA
                     MGIRYF"
     gene            28792..30273
                     /gene="guaB"
                     /locus_tag="TV188_000990"
     CDS             28792..30273
                     /gene="guaB"
                     /locus_tag="TV188_000990"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEL1534358.1"
                     /translation="MSNWDTKFLKKGYTFDDVLLIPAESHVLPNEVNLKTKLAKNLTL
                     NIPIITAAMDTVTDSKMAIAIARAGGLGVIHKNMSIAEQAEEVRKVKRSENGVIIDPF
                     FLTPEHKVAEAEELMQRYRISGVPIVETLANRKLVGIITNRDMRFISDYNAPISEHMT
                     SEQLVTAEVGTDLETAERILHEHRIEKLPLVDDNGRLSGLITIKDIEKVIEFPHAAKD
                     EFGRLLVAAAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDK
                     TLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGY
                     VGAGTIRELHDNAQFVEMSGAGLIESHPHDVQITNEAPNYSMH"
     gene            30654..31046
                     /locus_tag="TV188_000991"
     CDS             30654..31046
                     /locus_tag="TV188_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1534359.1"
                     /translation="MNRFLKISLLIVGVIVIMLGMEVKHRMDIYDQIKQEEIKIAQSK
                     EAIVIYEQELKWLDPNALTNEGTIKSYSIDLDSITLNPMGGFSIALHINKNPKYKYRI
                     SLMWNTPMRDLCVGGSSLSPELQELLDR"
     gene            31121..31522
                     /locus_tag="TV188_000992"
     CDS             31121..31522
                     /locus_tag="TV188_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1534360.1"
                     /translation="MKTLLKLIVFIVGTLVLMLGMEVKHRMDTYDQIKQVELKNAHSK
                     EVIEMYEQELISMDPQALTDEGLIKSYTIDSDSLFINPMGGFSIHLIINDDPDIYLRV
                     GLGRYDMERNLEIDGIYRSEKLEKLLKGVER"
     gene            31519..>31750
                     /locus_tag="TV188_000993"
     CDS             31519..>31750
                     /locus_tag="TV188_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1310 family protein"
                     /protein_id="HEL1534361.1"
                     /translation="MKTLLKLIVFIVGALVLILGMEVKHRMDIYDQVKQVELKNAHSK
                     EAIDIYEKKLKRLDPQALTDEGLIKSYTIDSDS"
BASE COUNT         9884 a         6363 c         5841 g         9662 t
ORIGIN      
        1 agccatagca tgcatagact acaataccaa gtatagtgct gataccaaaa gcaatccacg
       61 taaataccat atactgactc ataaaggtta cacagatgat aatagctaaa attggcaata
      121 gaggcacaaa aggagtttta aactccccac gttgaggctc tccagcgttt tttcttagct
      181 taatgatagc aaaggacatg atgacaagat aagcgagagt acagatattg acaaactcag
      241 caagactggc tagggggaat attcctgcac aaatcataga taatgcacca acaactaggg
      301 ttgcatttct aggaattctt gttttttctg tgatttgaca aagggctctt ggtaaaagtc
      361 catctctact gatactgtaa accgttcttg ctaaggcata ggtcattgaa atacaaactg
      421 taattagagt taaaatggca acaattgaga cataatctgc tgcccaatat aacccaatac
      481 tccttaaagc aaaggcaact gcatcaggta catctaattt tgtatagtga acaatcccag
      541 ttaaaaccat tgtaacaata acatataaga tcgttacaat cgttaaggat aatacaatac
      601 ctcttggaat tgttttttgt ggttctttga cctcatctac tgtcatggaa atagactcaa
      661 agcccaagaa agcaaaaaac atgactgagg ctccagcgaa aatacctgac ttaccaccat
      721 aaatttggcc aaagccataa ggcgcaaaat gtgaccagtt ggctacatca ataaaaaata
      781 agcctacaat gacaaataaa gccagagctg aaaattttaa cagaactaaa aagctattga
      841 atcgcaatgc tgcctttgaa ttcatcaata caatagcagt cactaatagc atcactagca
      901 ctggaagtaa atccacatag gtcccctttt gaggatcaaa ggtaccattt aaagcattgg
      961 gcaattgtaa gccataatta gccagtaagc cttttaaata gctcccccag ccgacagcta
     1021 cacttgaaat tgctgttaaa aattccatga tgatatacca gcccacaatc caagctggaa
     1081 attcacctaa tgtcgcatag acatagctat aagcaccacc atttgctgga attcgtgaag
     1141 caaattctgc ataaaagagt gctaatatac taatagcaat agcagataga ataatagaaa
     1201 tcgtcagcgc tggtcctgca taattagcag ctcctatgcc tgtaatagtg aaaattcctg
     1261 ttcccaccat tgatcctagg cccaaaaaaa tcaaatccag catttttaag tgcctattca
     1321 tttcagtctt attaatagct tgcctttttt tacgaaagat tgtcatcttg tcactttcta
     1381 gtcttaaaat agttctactt agtttatcat agttcctgac aattgtaaat ttcactaaaa
     1441 tgaccccaat atagcctaag acctattaaa aaacgagcta ggaccaaacc cagctcatct
     1501 tatatatcaa taatgactaa ttatttattc tttagcttct gtcattttat ccttgatttc
     1561 atcataggat aaggcatgta cctctgcttc atcgttttct ggatcatttg gcattttacc
     1621 agtctcgtaa atggacttaa tttgagcagc atccaacgtt tcatacttaa gaagtgcttc
     1681 agcaatcagc ttatgagttt cacgatgatc attaataatg tcagcagcct tgttacgagc
     1741 ttcgtttaat aaatcacgaa cctcatcatc aatcatttga gctgtttggg cagaatatga
     1801 tttttcaggt gacaattgcc ctggcatcat agcatgattg ccttcatatt ggactggtcc
     1861 aagtttttca ctcataccat actctgtgac catagcccta gccatttgag tggcctgttc
     1921 aaagtcattt gaagcacctg ttgtctgagc attgaaaata atttcttctg caacacgacc
     1981 acccataagc cctgcaagct gctccttcag atcatcttta gataaaagca tttgatcttc
     2041 ctttggaagc gcaatcatat agccgcctgc tcggcctcga ggcacaattg ttaccttgtg
     2101 cacaacacga gcattggata agactaaacc aacaatagta tgacctgcct catggtaggc
     2161 aaccatttcg cgctctctct gtgaaatgct acgatccttc ttagaaggtc ctgcaataac
     2221 acgatcctct gcctcatcaa tatcactagc atcaatttta gttttatttc gacgcgctgc
     2281 aacaagggct gcttcgttta gaacattttc aaggtctgca ccgacaaaac ctggagtttg
     2341 ttgagcaaca accttcagat tgacatcctc agcaagtggc ttatttttag cgtggacgcg
     2401 taatatcgcc tcacgcccct taacatctgg tcgaccaaca agcaccttac ggtcaaaacg
     2461 acctggtctt aacaaggctg gatctaagac atcactacgg ttggttgcag caatgacaat
     2521 gatgctttca ttaccttcaa agccatccat ctcaataaga agctgattaa gggtttgctc
     2581 acgctcatcg ttaccaccac ccatgccggc accacgacga cgaccaacag cgtcaatttc
     2641 gtcaatgaaa ataatcgctc gctcagcctt tttagcatct tcaaataaag aacgcacacg
     2701 actggcacca acaccaacaa acatctcaac aaaatctgag cctgaaatgc taaagaatgg
     2761 tactcccgcc tctccagcaa cagcctttgc aagcaatgtt ttacctgttc ctggaggtcc
     2821 ctccaaaaga acaccagcag gaatgcgcgc accgagtgcc ttgtatttct taggattctt
     2881 tagaaaatca acaacctcta ccagttcttg tttttcttcc tcagcaccag ccacatctgt
     2941 aaatctaacc tttacatcac cctttgcttg tgatctagcc ttatttttac caaaactcat
     3001 ggcaccacga gcaccaccac cttgattcat gatcatcatc atgaaggctg caaaaatcac
     3061 aatcggcaga aagctcataa gaaaggtaat ccaagcccca cttgagcttt cttgttttac
     3121 agtaatgtct gttccatttt tatctgcgac agaagtcatt tcctttaata cagaatcaga
     3181 tggtaaaatt aaggccgtaa attctgttac ctcagtggct gcactattac ctaaaaatga
     3241 caagcctgtg tcaatagaca ccttttgagg cttttcatat tttcctttaa cctcaacaat
     3301 gctgccacta ggctgatagc taagtgattt aatatcacct gccttcaaat gcttaattaa
     3361 ttttgaatag ctaatttgct ggctttgtgt actagttcct cttaagtaat attgaaatcc
     3421 tgctacaaca ataacaatca tcaatatata tataaaagaa tttttgacaa atccattatt
     3481 tttattattt ttcatacaac aataattgac cttttcctat tttgaataga cttcctcttt
     3541 taaaacaccg acataaggga gatttctata attttctgcg taatctaatc cgaagcctac
     3601 aataaactca ttaggaacat tgtagcacac atagtctgcc tcaatgtcta ccacacgacc
     3661 ctctggcttg tcaaatagtg tgataatctt aacggaatta gccttacgat atttgaacat
     3721 gtcacgcaaa tatttgagtg ttcgaccagt atcaataata tcttcaacaa agatgacgtc
     3781 tcttccctca atattggtgt caacgtcttt taagatttta acctctccac tgctagttgt
     3841 tccaccatta tagctagaaa caaccataaa atcaatttca acgtgagtgt caatgtgctt
     3901 catcagctcg gccatgaatg gaacagaacc ctttaagaca ccgaccatca agggattttt
     3961 accatgataa tcctttgtca actgctcacc aagctccttg gtcctttgaa taatgtcatt
     4021 ttcagaataa agaatttttt gaatatcttg ctcaagcata ctgtcacctt ttttctaatt
     4081 tatcaatata cagtttagcc aacattatat catgtttaga cgcttttctc aaatatgttt
     4141 catcaccaac cagcacaaaa ataataactc cagcctgttc tcctacgatg gcattttgac
     4201 gctgctcact tgtaaacttt ccatcgatga ataaacgtct taattttttt gaaaattcac
     4261 caagaaaaag cctatctcct gcctgcctat gacgtaaagt aactggtgat aagctatata
     4321 aagggatagc tatatcatgt cccttatcag tcaaactacc tgagaaaaca aatcgatacc
     4381 ctctataatt tagggaatca ccgtatgata ccattttaaa ttctcgattt aaatcagtct
     4441 ttggaatgat ttttttaata gcaaaagact ctttttcaat gaggagacaa taagtatttt
     4501 taattggata aatcccctgc ttttgtcgtc tgatgatgtg taaaagatca tcaaattgtg
     4561 attttttaat ggctagctgt ggaaacgttt ctaaataatg ctgaagcaaa aaaaactgaa
     4621 cagcagctga ttgagctaaa aaacagttta atcgatgaaa ttcaagtccc ttggttaaat
     4681 catcaaaggc ctgaagcagc aggcgacttt ccgcagataa atcaatcaaa gattgagtag
     4741 cttgaggatt ttctcttttg aaatctggca ggtaatgatg acgaacacga ttgcgaaaat
     4801 aagccatgct gtcattagaa tgatcttcaa aatgaaaggg attaggcagt tctgcttttg
     4861 ataccgttaa aaacggtcgt atcaactgac cattagcaaa gggctgaacc tctctgatac
     4921 cagctaaatg acgcaatcga ctaccacgaa tcagtctcat caaaatagtc tcagcctgat
     4981 catcagcatg atgtgctgtg actaaagccg aataatgctc ctgctgcatg atctcttcaa
     5041 aaaattgata gcgaagatga cgcgcagcat tctcagaaaa agcgccctga aaataagcaa
     5101 catagatagg aatagcatgc tttttagccc aagacctcaa ataagcctct tcgtcatctg
     5161 attctggtct ttgcttgtga ttgacatgcg caatgccaat ccgaatttgc aattttgctt
     5221 gaaaagcatg caaaaagtgc agcaaattca tcgaatctac tccaccagat acagctatca
     5281 aaacagcctg atgagcgtca aaataggcct tcttttttat gatgttataa atgtgttgat
     5341 aagtcatttt aaaatcgaat aaacatcgtc agcaattgct gtgatgtcgt cataggaagc
     5401 cttatctgta aaaacggata agataaaggg attatcacca taaacaatgg caacatcatg
     5461 cttgtaatcg taggcgtctc caatcttgtg agccactggc acagaaatat tttttgaaat
     5521 gcgctgatca tcaaatgccg tctgtgacaa ataagaaata atctgacctt tttgataata
     5581 gatagcttcc atgagatttg ctgctgcatg agaagaaagc aagcgctttt ccatgtccca
     5641 atctactcca gctaaagccc taatctctga ttgaaaggct tgattatatt gattacatag
     5701 gtagtagcct aagatattag tagcaacatt gtcagactgc tgagccacag cctttaaaag
     5761 ctccatcaca ttatagtcct ttttgtcagc tgttttactg attttaccac tgccagttgg
     5821 atcgtaatca ccataaaaat gattgacctc atcaatgtat tttaagctct taccttcaga
     5881 taagctacct gacttcagtt ttttttgaac actgtacagg gttgctaatt tggaaatact
     5941 tgccgcatac atctgtttat cagcattgat acctgcactg gcctgcgtgt taagctgctt
     6001 tacaaaaata gaataattct ctttattata tttttgcaat agcatttcct gaaccttcaa
     6061 catgcgattg tcggtaggtg acaactcctt ttgattaacc cagcccttat gatcaatgaa
     6121 ataataggtc ccatgctctg tttgagccat cttactagca tgaacctttc tgccaggctc
     6181 actatctgat gcaattgtct taacacctaa aacatagggt tcagcatata tagtcatctt
     6241 tttttgagtc caaaaatcca aatccacagc tgtctgctca aacataatat cctcgtaaac
     6301 aatctgacga ctagcttcaa ggtaagtgtc atctgccagt ctaaagacag gaatagctgc
     6361 cttgtttagc aaaacatcct tgataacaat tctattgtct ggtgcgatca tcgtctttgg
     6421 cacactcaat tcgggatccc tataagcaac tgtctcctca aaaacattgg gattagtcgg
     6481 aatccgacta taataaagag tggagctaac aatatcctga cttaagtgat agcgtgtcgc
     6541 ttcagaaaac actgggattt tttctgtact aatgaccgtt aaaggagtca cgaaaaatgt
     6601 cattaacata gctgctaata attttttcac aatggctcct tcctatttta cttctgtgcg
     6661 atgatggtct ttcttcagct cttgattttc cttttctagc tctgctaatt tgtcatcaga
     6721 aaaggcaaga aaggtttcaa ttttttcgac aatattatcc atagtcaatt actattttgg
     6781 taataatcca ggagttggat aaataacctc tccttctctt gataagtaat atttagccct
     6841 agcatacttt ttgacaaaat catcattttt tagctgctca gctaactgct tttcagactt
     6901 agtctttttt tctaactcac gatactcttt ttccaacgta ataatctgct gaccttgttt
     6961 tttcagtgaa acataaccct taaccaagtt ataggttggc agaataaaca agaacatcat
     7021 actaaccaag atccaaccca taaaacggtt ccgtttttgg atttcctctt cctcaaaccg
     7081 ttttttgata ttttcttcgt tgatataatg gttattcaac tggacgatac taggcttctt
     7141 catcgctact tatccttgtt tcgctgataa tgtcatacat tttagcagcg tcctcttttt
     7201 tagtgctatc cttcatatca agcacacgaa cagtaagcaa cttattgcca aacctgattt
     7261 caacctgatc atttagtttt aaatcagttg agcttttcgc aaggatacca ttaaccttaa
     7321 tacgtccctt atctgcgact tctttggcca ctgatcgacg cttaatcaat cttgatacct
     7381 ttaaatattt atctaatctc atatcttttg cctcacaatc cctttcattc tatcattttt
     7441 ctttgacaaa tggtagaaaa gaccacaatt tctctttaaa gacacctagc tttttgcaag
     7501 ctattaaaaa agaggataaa ccaacagcag atgacaccaa aagactaatc agcgcaccaa
     7561 gtcgacctga taatggcaag caatactgac ttgtaagcac acacatgagc atgatcacta
     7621 aagcaagccc atatttagca ttcactatcg ctttaaaatc aatatcagcc agcacagcat
     7681 acaagagtaa aacgaccagc aaggggatta gggtggataa ggagcttcca acaatagcgt
     7741 aatagtaggt taatataggt gttaagccta attttaataa aaagccaaac agcaaaataa
     7801 gcaaagattg cttgatgtga tcctcaatga agcatttttg atgaaagaat tgaatcatgc
     7861 ttgatactgc tataatcatc aggtaaacca ctaaggccag ccagccctta ttgtcctcaa
     7921 ataaggctcg attcatcaga tggagaatac taataaaacc aacagtcagt gttaaactaa
     7981 aataaaagat aaactcaaag aaacattgac tttgctctct ataggactcc cttttaatat
     8041 gaaacaagac tgttaaattc ggtaaataag ctgtaaataa ggccgtcgaa aaaatgagac
     8101 caaattgcag caagggctgt cccctatcgt aaacaccctt agtcatttca gctgttatct
     8161 ctgataagcc tgagctaacc aaaatatttt tcaccaaaag agaatctatc aattgaaaaa
     8221 caagcaggta aattgaaaaa agtaaaaaaa ctaaggtcgg caagcccaga cttgttaaat
     8281 ctctaatagc aaccgtatct cctgataaaa agctttttaa tgaataagca ctatgacgct
     8341 tcaaataagc taaaataact aagctcgcta ctaaatttcc aaaagcagca acatttgctg
     8401 ttaaataaac cgtccaacca agcaccctgt agcatagtgc agcaacaatg attatagcaa
     8461 ctcttatgat ctgctcaaga acctgactca gagctgtagg agccatattc atatcagcct
     8521 gggctaagcc tctgtaaaag gatataaagg gtactattaa caaaaccatt gctgttataa
     8581 caattgatgg tgccaactgc tgtgctccca tccagctagc caatgcctta tgacttagca
     8641 ccaatattcc tgacaataag aagctggtat agcattgcaa cttaaataga gctgctagct
     8701 gtagctgctt ttttttctgg gccatactgg caatcacatt gggtaaagca gttagaccta
     8761 aggctgaaat aatacctagc aaaggataga tttgttggta agcataaaag cccctatccc
     8821 ctaccaaatt ttgataaggg atacggtaac tggctgctaa taattttgac ataaaaccac
     8881 taataacaat cagaagactt gattgcttag ttttatgagg aagcttttct agatttaatc
     8941 tcaccaagtg tctctccaaa aagtatcaat tcttctaaaa tgacatggtc tttctgacgt
     9001 ctaacatcaa agataatttc aattttaccc tgatgctcac taatccttgc ttttaagctt
     9061 gtttttgaca gagcctcaaa ataatcctgt gtcaaatagt attgaagcga agcaacctca
     9121 aacctaacca taacctgatg gtccctcttc tcgactaatt cagcaaaggc tgtatccaag
     9181 tagtatttca acaagccaat ctccagtaaa taggctacct gatcaggata gtcaccaaaa
     9241 cgatccatga tttcatcttg caaatcagaa taagctgctc tagagtcaat ctcacgaatg
     9301 cgcttataaa tgtcaatttt ttgacgctcg tctttgatat aatcactagg taaataagca
     9361 tcaatatgca gattaatctc tgcattacct ttttgtcgcg tcaatgctct tccttgcttg
     9421 cttgcaatag cctgctccag cagctgagaa tacatgtcaa aaccaactga gtcaataaaa
     9481 ccactttgtg aagcacccaa tatatttcct gctccccgaa tagataaatc tcgcatagca
     9541 attttaaagc cagatcccag ctctgtaaag cccttaatag cttctaacct tttttcggaa
     9601 acctctgtta gtaccttatc aggcttatac atgagataag cataggcaat acgattgctc
     9661 cttccaacac gacctcgaag ctgatacaaa gttgatagtc ccatatgatc agcattttca
     9721 ataaataagg tattgacatt agaaatatca acccctgtct caataatagt tgttgcaact
     9781 aaaacatcat aatcaccatt gataaaatcc atcaaggtat tctcaagctg aatgtcactc
     9841 atttgaccat ggacaaaacc aatagaagcc tctggaacca attcttgcag ctctgccacc
     9901 ttcttgtcaa cagtgtcaac cttattgtaa acataaaaga cttgaccacc acgatccatt
     9961 tctcgaataa tagcttccct aatcaagcca ggattatttt ctaaaacata agtctgaaca
    10021 ggatagcgat tcgtaggagg cgtctcaatc actgataaat cccgaatacc aagcatagac
    10081 atatgcaggg tacgaggaat aggcgttgca gtcagtgtaa ggacatcaac cttggtcttt
    10141 aattccttta gggtttcttt atgcttaaca ccaaaacgct gctcttcatc aatgacaatc
    10201 aagcctaaat ctgaaaaaat cacatccttt gacagcaacc tatgagtccc aataataata
    10261 tcaacctgac ccttttttag cctttctaga ctttcagatt gctctttttt actgcgaaag
    10321 cggcttaaaa cagcaatttc aaccggatag ttctcaaatc tttccctaaa attctcataa
    10381 tgctgctgtg ctaaaacggt tgttggtact aagatagcta cctgcttatg gtcaccgata
    10441 gccttaaaag cagctctcat agccacctca gtcttaccaa agccaacatc accaactagt
    10501 aaacgatcca taggtctgac actctccatg tcttttttaa cctcttttat ggacctaact
    10561 tgatcatcag tctcaacaaa ggcaaaatcc tcctcaaatg ctctttgtaa ctcatcatct
    10621 ggagaaaact gaaatccttt ttgctgactc cgctctgcat aaagcttcaa caggtcatct
    10681 gcaatatcct caacttgctt tttaaccctt tgctttgctt tttgaaaacg accatcgttt
    10741 agtttattaa tctttggctc tttaccatct gctgatacat attttgataa gctttcaagc
    10801 tgatcaacag gcaaagaaat tcgatctgac tgctgatact gaatggtgac ataatctcga
    10861 tgtacccctt gtatgttaat cgtttcaatg cctaaaaaac gaccaatccc atgcacactg
    10921 tggaccacat aatcaccctt agacaattca ttgtaatcct ttaagcgttc agcattactc
    10981 atattagtac gacgagcacg acgcttcagc ctcttatgat atatctcatg ctcagtaatt
    11041 aaaactaatt tttcatcagc aaagtaaaac ccacctgcta ggtgaccaat aatgatttgt
    11101 gcttgatgta atactattgc atcagcagaa acaaggggca attgacattg ataagcctca
    11161 agagattttg ccaaccgctc ataagcttga tgagattcaa cctgtaaaag gacagttgct
    11221 ccagattttt gataccgctt aatctcatca atgagcagtg gaaattgatt gaaaaattcc
    11281 tgcatggcat actgtgttaa gctatacacc ttatcaaatt taatattacc aagtcccttg
    11341 tgaaaatttg aaaagaaggt ggcaggctta tagtgtcgca gctcacgata attgtcagca
    11401 aaataatgga gaaatggaag tgactttcct tgctgtaaat catctgtcaa caaatgagca
    11461 agctctaagt caaatttagc atttctgtca actaactttt ggaaatcatc aaaaaatact
    11521 ggtgttccct taggaaggta atctagaatc gtccattcat tatcataaaa cagtgattga
    11581 aatttacgga tgtccttatg cttcaggcct tcttttgtta cagtgagcaa ctcctccaga
    11641 tagcctttat gttctgcctt agcaagttga agctgctttt caagattatg actagcccta
    11701 tcaaaatcct ccggctcaaa aatcatatca cttgcaggct tgatactggt gctatccttc
    11761 ttttggagag atttttgact ttctatatca aagctcctaa taccatcaat ctcatcacca
    11821 aaaaattcga tgcgaacagg taagtcctgt gttacctcgt aaacatctaa aatatcacct
    11881 cgtctgctaa attcaccagg actaaggacc tgagccaccc tttgataacc aattttgaca
    11941 agcttcttga caacgttgtc aagatcagtg tcaactccta ctgctaagtc aatctgcccc
    12001 tgctgaaaag tcttaggact tggaagtagg attctgagtc ctgctaagct aatgaccaat
    12061 attcctcttg cttctggatt tgataaaaaa gctagtgcct ctattctcga gattgtttta
    12121 tccatagagg agaaaataaa ctcagccgca gcagtatcat ctgcaaaaaa ttgaaaaata
    12181 gagccctcat caagcaaggc tgacaaatca ccagctaatt tttccatgtc attttgagtt
    12241 gatgtcacca cgaccagctt cccttgaaag ctaagatagg ctgaggcaat ggctgctgct
    12301 ttacttgagc ctgacaagcc catgactaat tgccgtttta agcttgttac atcacattgc
    12361 caggtctgga ttgacttgtt ttgattaaat aattctaaaa tatccataac tacccattaa
    12421 attgctgcat tgttttctca atgctttttt cctgtaaata atagttgatt gctttgtcaa
    12481 ccttatcaag tgctatattg attgttatca tatcatctgt atcaaatttt cctagaacat
    12541 gattaataac actcattcca tgacttggtc ttccaatacc aattttaacc ctatcaaatt
    12601 cctgtgtacc gatatgagca ataatggatt ttataccatt atgtccccct gcagagcctt
    12661 tttgacgcaa acgaatttta ccaactgcca tatctaaatc atcatagatg accattaaat
    12721 ctttagttga aatattgtaa taggtcaata aagccctaac agcaagacca ctattattca
    12781 taaaggtagt tggcttaaca aaataaatct tttcttgatt gataaaagta ctcccaataa
    12841 gggctttgaa ggttttatct tctgtaaagc taacgtcaag atccttgaca agtctgtcaa
    12901 ctgccataaa accaacatta tgctttgttt gctgatgttt tgagcctgga tttcctaatc
    12961 ctacaatcat ttttaccata ctaatacacc agagaaacga ggtatgatag cagcctgttg
    13021 accattctta aagctttatc agcctcttcc cctctatttt ttgtcctttc taagcttttg
    13081 ataggcacca aaagggctgg aatactatcc caaccctaga acacaatatt gttaccacta
    13141 aacattgaat ctaaattcca taatatcgcc atcctgaacg atatattcct ttccttcctc
    13201 acgcagacga cctgcctctt taacagcctt ttctgagcca tacttaatca aatcatcata
    13261 gctcatcgtc accgcacgaa taaaaccgcg ctcaaaatct gagtgaatga taccagctgc
    13321 ttgtggtgcc ttaataccgc gcttgaaggt ccatgcacgc acttcctttt caccagctgt
    13381 aaagtaggtg ccaagtccaa gtaaatgata ggctgcacgt gtcagcttgt caacgccaga
    13441 ttctgtcaga ccgatagctt ctaaaaattc actcctgtct tcatcatcta actctgaaat
    13501 ctcttcttct gcacgagctg aaatcacaac aacctctgca ttttcagttg ctgcaaagtc
    13561 acgaatctgc ttcacataat caatagcgtc tggaattgct accttatcct catcaacgtt
    13621 tgccacataa agcactggct tagtcgttaa taaaaataac tgcctaacaa ttttttgctc
    13681 atcatctgta aagctaatgg tacgagcaga tttgccttct tcaagcactg gcttaatttt
    13741 ttcaaggaca gcaaattctg ctacagaatc cttgtccttt tgtgtacggg ccattttttc
    13801 gacacgcgca tagcgtttat tgattgattc taagtcagcc aaaattaatt caaggttaat
    13861 cgtatcaata tctgccaaag gatccacaaa ggcatcctca cgcccctgct cacgcatgac
    13921 attttcatca tcaaaggcac gaaccacatg aacaatagca tcaacctcgc ggatattggc
    13981 taagaactta tttccaagtc cttctccttt tgaagctccc tttacaatac ctgcgatatc
    14041 tgtaaattca aaggttgtag gtactgtttt tttaggcgtg ataagctctg tcaacttctg
    14101 taaacgctca tctggaacct ctaccatacc aacattagga tcaattgtcg caaaaggata
    14161 attagcagcc tctgcccctg cttttgtaat tgcgttaaat aaggttgatt tcccaacgtt
    14221 tggcaaacca acgatgcctg ctgttaaagc catatttttt tcggtctccg ttacattttt
    14281 tcaatcctta tcattatagc aaaaaaaaga agaaaaagct tgcctagtaa tgatctttaa
    14341 ctaaaatgga tcacaataaa atacacacct aacaaaacga tcacaaccaa taatagcata
    14401 agaagatcgc ctttacgcat tggccgctta gattcctcag ttaaaaattc ccatacgttc
    14461 attggctttt cagttttctt aataaccttg attgcaggtt cttttccagt caccaattca
    14521 tctaaagtta cctctaaaac agctgccaat gtaactaaat tttccaaatc cggtgtcgca
    14581 tctccatttt cccactttga aatagcctga cgggagatga aaagcttctc agctaaggca
    14641 tcctgagaca actgcttttc aagccgatac ttctttaatt gttctgcaaa tttagtcatc
    14701 attaatgacc gcctttcctt tttgatagct ttacaataac tcttttttaa aaggcaagct
    14761 agcaattttt aacgcaataa tgagttgcga aggtagttaa aaaccttatg acaatagagc
    14821 ttctatggtt gcagaacctt cttcatttta cgctcaaaat catgacgact tagcatgata
    14881 acatgattac agttagtgca ttgcagctta atatctgctc ctactcttgt gattttccat
    14941 tgatttgcct tttttcctgt ttctttaatg acacaggcat ggggcttttt catttcaatt
    15001 aaggatccaa cttgatacat cactttatca ctcactcatc tcttatattt attatttatc
    15061 ataacaaaaa aagcccccaa aagggagcgt ttttcgctta gtttgtacga actggtgtga
    15121 ttaattgaat aaagctctct tcatcatctc ccggtgttaa ggtgaaagga cgaacaggcg
    15181 ataggaagtg aatcttaacc gtctcacttt taatggcttt taaggcttca atcagatagg
    15241 ttgggttaaa gctaatggtt aaatcattcc ctgcttgact caccacgtcc agatcctcgt
    15301 taaccttacc aacctctgga gagttaacat gagctgaaat gcgatttgct tcaatttcaa
    15361 gcttaacagt accattttgc gtagcgtttg aaatcaagaa agcacgctcc atagcatgtc
    15421 gtaaggattg tgtgttaaaa acagcctctg tctcaaactg cttcatcagc aaacgatcag
    15481 tatcagggta attaccttct aacagacggg tgtaaaaaga aatgtagtca cttctaaata
    15541 gcatttgact agcagaaaag aacacttcaa cggtttctat atcatctgta aagacagctg
    15601 aaaattctct caaggattta cttggaataa ccacatcaaa atcagctgag gttttctcca
    15661 gagtaatcaa gcgctggctc atacgatgtg aatctgttgc caccgcttta aagttcttat
    15721 gctgacttag ggtgatgtgt acgcctgtca aaataggacg actttcctgc atactagcag
    15781 caaaggctgt ctcagcaatg atagatttta agagtcttgt atttaaaatt aaaggatttt
    15841 cagttgatac ctcttgaaga cgtgggtatt gagaaacatc cttccccttt aaggtgattt
    15901 cagatttccc actggttagc accacctgat gctgttcaat ttccttaaat tctaagctaa
    15961 catctggaag acttgagata atattgataa aaaagctggc ttctaaaaga acagcccctg
    16021 ttgaggttat caacaagcct gcgttttcat tgctaacagg aatggtattt tcaatagaga
    16081 tttgaccatt agagccagtc agggtaatgt ctgatggatt aacctcaatc ttgatggttg
    16141 ataagatcgg tatagcattt ttactgctga tagccctttt agtggctgtt aaagcttgaa
    16201 tgaaaagggc tctattgata gaaaattgaa tcatggtaac tcctttgtta tataagtatt
    16261 atagctagta gtagtagtag gtcttgttaa aatagtggat aagtctcctt gtactagtcg
    16321 ttactagtta aaacgcttgt gcacaagctg tggataaatt ttcctttttg ctaaaggtta
    16381 tccacattgc ttatttgatt ttgttcttga tggtttcaat ttcaattctg aggctctcgt
    16441 cttgtccaat catgttttta attttgttat aagcatgaag cacagttgaa tgatcacgtc
    16501 ctccaaattc tttaccgatc tttggcagac tgttatcggt catctcacga gctaaaaaca
    16561 tagcaacctg tctagcaagc acgatatcct gtgtgcgttt ggtcgccttg atttccttaa
    16621 ccgtaacccc ataaaatttt ccaacctgag cttggatttc ttcaattgga atgacagtca
    16681 tcttaggacc gtcttgcttt ctagctcgaa tagcttctgc tgctatgtct actgtaattg
    16741 tatcaatttg tttaaaatta gccacaagac taatatcctt caaagcccct tccaggtctc
    16801 tgacattaga gtcaaattga ccggccaaat attcgatggt gtcctgagga aagatgaaat
    16861 tatattcttg aattttattg gtcaaaatag caacacgtgt ctcaaaatca ggcggtgtga
    16921 tattaactgt tagtccccac ttaaatcgag ttactaggcg atcttctagg tcattgaggt
    16981 gatcaggggt tcggtcactt gttaaaacaa tttgcttgtt attgttatgt agagcattga
    17041 aggtgttaaa gaactcctct tgtgtaccag acaaggtttt tttagctagg gattgaatgt
    17101 catcaattag gaggagatca agattgcgaa atttctcctt tagctcgtcc atagtatcta
    17161 gacgaatatg aacaacaaat tcattaataa aattttcagc cgtaatgtat ttaatcctag
    17221 catttggatt ttccagtaaa actgaatttc caatagcatt taaaagatgg gtcttaccaa
    17281 gacctggacc tccccagata aataaaggat tataggttgt tcctggtgta ttagctaccg
    17341 ctattgatgc agcaacagcc cacctatttt catcaccttg gataaagttg tcaaagctgt
    17401 atttagggtt tagatcggac tgtactgctg gtaattgctg gaaggcttgt tcagtatatc
    17461 cttgctgtcc ctgatgctgt tgctcaatca tcaagtcatc ctcatagaca tagtctacag
    17521 caatttgagc attgtaaact tcaaatcctg ctgttaggat aacgtctttg agattttttt
    17581 cccaaaacaa ttccttcatc tgatctaaaa aaattgttgc gacatgattg tctaccttga
    17641 tcaaacgagc atcatgaaca aaaaattcat aagttgcctg ctttaactgg ctttgagcta
    17701 gctctaagac cctattccaa aaaatttgtt cattttcagt catacgagat tccttcttgt
    17761 ggataattct agaaccattc tatcataaat aaagatagtt ttccacaaag gatcaaggat
    17821 tattttagac ttacccacaa gctgtggaga taaaatacac aatgtgtaag atagttttcc
    17881 acaacttgtg gaaaaaagag aaagccttgt gataaaaggt tttagcccca tttctcttgt
    17941 ggaaaactga ataaaaaaaa cagacaatca acaagctaaa gcaacttgtt gataattctg
    18001 ttcaattctt cttggtttga aaatgacagt tgcagctgcc cactgtcatt tttttggaga
    18061 gacaatgcca caggtaatcc taatgatttt gagagctctt tttctaaaga cttcacaaaa
    18121 atggttttat gtttgtttct tttttttggg ggatgcttag tctttaccag ctgttcgatt
    18181 tgcctaacgc ttaagccttg atccagaatg ttgtgaaaat aaagctcctg ctcttttggt
    18241 gttgacaagg ataataaagc tcttgcatgg ccggcgctaa tggtaccgtc ctcaatcgct
    18301 tgtctaataa cgtctggtaa ttgcagcagt ctgatggtgt tgctgatata agggcgtgat
    18361 tttcccatgt atgtcgcgat gtcctcatgg gtcatcttat ttttatcaat aagtaattga
    18421 taggccttag cctcttcaat agcatttaaa tttgagcgct gtaggttttc tacgatggcc
    18481 tgctgcatgc tctcaagagt agagatttcc ttaacaattg ctggaatctt ttgaagtcct
    18541 gccagcttgg ctgctttaaa gcgtcgttct ccagcgacta attcatagcc aaatacatca
    18601 gattttctga caatgattgg ttgaatcaaa ccattagcct gaatggaatg tgccagctct
    18661 tcaagctctt tttgattaaa ttgaagacgt ggttgataag gatttgccac aatatcctcg
    18721 ataggaatgt gcattaggat ttctgtcata taagcctctc aaaagggaaa tagtggtagc
    18781 ttaacggtta ttagagatac atacgggata aaagagcaag agcccgcgac catcgtctcg
    18841 gactcaatct cacggggata cccaatgttt actgcttttt agttagatcc ttagttgttt
    18901 ttgttaattt gatgtcaact ttcttcttag cagttcctct gtagaaggtt accttaatgg
    18961 tgtcgttaat ctcatgacta tataagacac tttgtaggtc actaattgag ctgacttctt
    19021 taccgtcaac ctcagtaatg acatcatact gctccaattt accaagagca ggcatgccat
    19081 cttgagtaga ggctacgaca acaccgctgg taacgcttgt tggaatattc aattgaatca
    19141 atgcattggt tgatagatta cttaagttta ccattgtaat gcctaaggct ggtctgataa
    19201 cagctccgtt agactctagt tggttaataa tggtgacaac atcgcttgat ggaatagcaa
    19261 agccaattcc ctcaatggct ccgccgctac cagtaggtgt tgaggatatt ttacttgagt
    19321 tgataccaat aacctggcct tcaatattga tgagtggtcc acctgaatta cctggattga
    19381 tagcagcatc agtttggata gcatttgttg agatggtctc gcctgcctca tttcttgaag
    19441 tgactgtacg gcttagactt gaaacaatcc cttctgtcac tgagttggca tattttgttc
    19501 caagaggact accaattgca atggctacct ctccaacatt aattttggtt gaatctgcaa
    19561 atttggctat tgttttgatt ttatcagcag caactttgac aacagctagg tcagaataag
    19621 tgtctgcacc aactagttct ccaacgatct tagagccgtc tgctgttaaa atttcaattc
    19681 gttgagctcc ctcaataaca tgattgttgg ttacaagata agcagtatta ccttcttttt
    19741 tgtagacaac acccgaacct tcactgtgta tgcttagctc gtcctctttt tgtactgctg
    19801 aggtatcatt ttcttctccg aaaagattga tgtaaggatt tgaaatggca ggcgaagcag
    19861 ccttttgata gttaataaca gacactacag catcttgaac caccttaaca gcctttgttg
    19921 tatcagttgt attattaaag ctgacgttgc ttgttgtcgt tgctcccttt gcatttgaag
    19981 atgttagaga attctgacta aatccattaa caactaaggc agctaataag ccccctaaaa
    20041 atccaatggc taaaacccat aagggcttca atatattttt tgattttaac acaaaatcac
    20101 ctccgaatgg ttttcacata ggatataaaa cctcacttaa ttatacctta aaaccataaa
    20161 aaagaaaagt aatccacaac ttgtggaaaa cttttcagga ctatactaaa aaggctgtag
    20221 aaaagggttt atataaagaa aataagaaat caacatgtgg ataagttgtg taaaaagagt
    20281 tgattatggt acaataagga tatgaaaata aagcttattt gtgtcggaaa attaaaagaa
    20341 gcgtatttaa gagatgggat tgcagaatac caaaaaagac tgtctcgctt ttgccaatgt
    20401 gatatcattg aattagcaga tgaaaaaaca cctgataagg ctagccatgc tgaaaaacag
    20461 cagattatgg ctaaggaggc tgacaggatc aagaaaaagc ttggtcagcg tgattttgta
    20521 attgctttgg caatagaggg caagcaattg gcatcagaac agtttagtca tctactatca
    20581 gaggtcactg taaaaggcta ttcagacatt gcctttgtca ttggtgggag tcttggtttg
    20641 gatcaatcca ttaaaaatag ggctaattta ttgatgagct ttggcctatt gaccttacct
    20701 catcaattga tgcgtttggt tttaatcgag caggtttatc gtgcttttat gattcaacaa
    20761 ggcagtccat atcataaata gcagttgttt cacatgaaac actacacatg gcatagaaga
    20821 agcgcgtgta tacctcaacc atacttctag ctttcattaa tagggctgtt gatttgcagc
    20881 cttactcagc tattgcctga tgataaaagc attaattgct ttatcgaact gatgatttgg
    20941 aggttttgtg attttagcct tagacgatgt caggcaaatg cttatcactc ttatgactct
    21001 cctacgggag tcagtagctt actattgtta gaaatacaaa aagccattag atactgacta
    21061 atggcttttt ttactatttc tgatctcagc aggattcgaa cctgcgaccg ttcgcttaga
    21121 aggcgaatgc tctatccagc tgagctatga gacctcaacc accttatttt aacaaaaaaa
    21181 ccttatgcct gtcaatgctt atttttgata agaagcttca ctgccctaaa cgtgcggtga
    21241 tatgtctttt agcagtttgt atcagaggag caatgtgtta tgttttctag catgtttggg
    21301 gtaattagac ttgttttaga ctgtttatgt caaaagtgat caaaaaatca agattttttt
    21361 gaaaaaagta tagacaaata aaaacattct gctataataa taagagtgtt aaggagagtt
    21421 actcctgaac ttcaggtccg ttggtcaagg ggttaagaca ccgccttttc acggcggtaa
    21481 cacgggttcg aatcccgtac ggactatcag aattgtcttt gtggcaattt ttttattttc
    21541 cggcatagct cagttggtag tagcgcatga ctgttaatca tgatgtcgta ggttcgagtc
    21601 ctactgccgg agtgataaga cacttcctaa ggctttctta ggattttttt attgaccttg
    21661 aagagtgatt gtgatttgct aagaaactta aaaatacgct aatcgtctaa atgataggct
    21721 tctctttttt gggactaagg aacacgtgag ttatggaaag tcatgtgttt tgataaatat
    21781 ccttaaatca atagaccagc taaaaacact tgattttgat acctggaagg gctgtaaaat
    21841 caagcgtttt gcttatatat ggaaattgct gtttaagctt ttagcttggc tgtttgcctg
    21901 agtaagtagt aatgtaagaa gctgtaaagc aagataccaa taaatgagag cagtaagcct
    21961 aatgtaaagc catttggaac aaaggtgagt actaatttac cagatccttt tggaacatct
    22021 atcctaataa aaccaccttg agccttttta agagccactg gtcggccatt tagtcttgct
    22081 gtccagcctt tgtcataggg aagggtaaaa atcatagagc cttctgattt ggccttgtaa
    22141 tggctaatga cctgattgct acgggtgtaa gtagtaacct ctttttggtt aatcgcattc
    22201 atggctgcca gatagttgtc actatttaaa ctgtagaagt gtggggtagc aaaggaaata
    22261 tttttgtttt tcggaaacat aatagcaagg gttaaggttc ttcctttttc aaagtaccct
    22321 aagtcaaaga atgaaaaagc gttgtcagta gtgtactcgt aggtctgatc atcaatacgg
    22381 atcctaacag ctgttgcatt gtgatttgaa aagctaatat ttggaagact taagtagagc
    22441 tgcctatggt ttggtacagt aacctgataa tgaacaatgg ttgttgacgt attctcagca
    22501 gcctcccctg aaattctccc attaaatacc tgagcatttg atattagctt agaaggctct
    22561 agctgaaaat aggtgagcct ttttccactc agctgattca gcagcttggt ttgattgtca
    22621 agtgtgttga cagttaactt gacatctttg taaatgttat ctgttaagat agctagattg
    22681 ctgctatagt gattttgata gagtgtagtg tgatgactgg aggctatcct tgaaaagcca
    22741 aatttatgaa gctgatggta gctaagattg tattttatcc ctaaaagact atccatgatg
    22801 agagtgttgt tttgatagcg aaggtttaga tttgttccag cagactggta gcctagacga
    22861 tccagaaggg agctggagtg acgatttcgg atagatgaaa attgagaaat gccattatag
    22921 ctgtatttca tactatcatt gcctgtttgt ggtaggagct gctccagtct gaaaaactga
    22981 tcattgctat cagctgtttt cttgacaagt ctgtcaatat cctgtaaagc tctactatag
    23041 cccttacgtg atggaaacac ccattcatga tgaatgccat taagctgata ataggtattt
    23101 aaactggttt ctaaacagct aaacagtagg gtaaaaaaga ttaaaaatgg cattggtaca
    23161 gaggtttttt gcatgcttaa caataaaata agatatgccg ctaaaaaggc aagacttaag
    23221 atcaataaac taggctgtaa aaagctatac tgatccattg tcagataagg aagtgttaat
    23281 aagcagctta ataatataaa ggcaaagatt attctagtgt tagtaatgtc tttttgtcta
    23341 gaaagggctt cgcaggctaa aataatgata atgattgaaa atgaccacga atagcggtgc
    23401 aaaaacatat tgggtccatg catgccctgc caaaataaat ctaagggctg aagataaaag
    23461 ctagccatga tgagtcctaa aagcagccca tagcccagtc ttaagcgcca gctaatagat
    23521 tttaaggtga aaaagacgat acttaacaat gaaggcaaca gaccaataaa tatcatggga
    23581 atcgcattaa actttgtcgt atcataggca ccaagtgata gctttgctaa taaatcaaag
    23641 gctcctatag gcttaatgat aatctgattg attggagaga gtgtttcacc gtaggctgtt
    23701 aggtctagat aggccggtat gagtataaaa gcacttgtta aggctgataa gattgacact
    23761 gatgtaaagc ttaaacaggc tcttaaccgt cttttccatg tgtctagtga tataaggttg
    23821 actagaaata ataaaaaaat aaagatagca accatatatc caaaataata atgctggata
    23881 aagagaagac taagtgagct ataataaagc aagggcttgg tttgagtaat cagccgatag
    23941 agccccagta agacaattgg tagaagaata aaaacatcta accagttgtt aagctctagc
    24001 tggcttgtca gaaagctcat tagggagtaa gagactgata atgtcaggac taaaaagggt
    24061 ttgattttag ggtaaatacg atgaaaggag aaataagcgg caagcccgat caaaccaaat
    24121 ttaataagtg tcaagagata gatagcatct ggcatggatt gcagattaaa aaaatagaca
    24181 agaggagaca aaaggctgcc tagataatag ctagccagag caaaaaagtt tacacctagg
    24241 ccactggtaa aggtgtaaaa aatactatca gccccatgaa gaatatttct tagggcttgc
    24301 gcaaaaataa catattgatg aaagccatca ctagctaaaa tggttttctc actgccatat
    24361 gaaattccca ttgacaaaag aacaaaaaac attatcaaaa agggaaggag gaagctagca
    24421 atgtcataaa caagagacca tgctttaggt tttgtcataa ataagccctt ctatgatatt
    24481 tttgaaaaaa gagctagaaa tagtttccag ccctcagatg tcatcggtga tcatctctat
    24541 actttaatga tgatattgag caaagctcct tgtttcttcc ttatttccaa agctctgcta
    24601 ccttagcttg aacgtctttg ttttcaagga attcatcata ggtttcgtca atacggtcaa
    24661 tcacaccatt tttagaaata acaacaatgt gattagcaat ggtttggata aactcgtggt
    24721 cgtgactggt aaaaataaca gactctttaa aatctttaat cccgtcattg agacttgaaa
    24781 tagattccaa atctaggtga ttggttgggt catcaagaag gagaacattt gattttaaaa
    24841 gcattaactt tgatagcatc acgcgcacct tctcaccacc agagagaacg ttaacggatt
    24901 ttttaacctc atctccagaa aagagcatac gtcctaagaa accacgcaag aaggtatcat
    24961 catcttcacc ctttgctgca aattggcgga gccattcaag gatagactca tcgctagcaa
    25021 agtcacgtga gttgtccttt ggcagatagg agcgactagt tgttactccc catttgatag
    25081 tcccttcata gtcaatgtca tcagccagag cgcgcataag agctgttgtt tgaatgtcat
    25141 tttgtccgat aatggcagtc ttatcacctg gccttagaat gaagctaatg ttatctagaa
    25201 ttttgtcacc atcaacggtt acagacaaat tttcaactgt tacaaagtca ttgcccattt
    25261 cacgctcagc tttaaaattg atgaatgggt atttacggct agatggaata atctcttcta
    25321 gctcaatttt gtccagcatt ttcttacgag aggttgcttg ctttgattta gaagcattgg
    25381 cagaaaagcg tgctacaaat tcttgcagct ctttgatttt ttcttcggcc ttagcattac
    25441 gatctgcctg aaggcgtgca gctaattcag atgattgctt ccagaaatcg tagttaccga
    25501 caaaaagctt aatctttcca aaatcaaggt cggccatgtg agtacatacc ttgttcaaaa
    25561 agtgacggtc atgtgacacc acaataacag tattttcaaa gtcaatcaag aagtcttcta
    25621 accatgaaat agactgaata tcaagaccgt tggttggctc gtctagcagc aaaacatcag
    25681 gcttgccaaa aagtgcttta gctaggagaa ccttcacctt atcaccattg gtgagctcgc
    25741 tcatgctttg ataatgcaat tcctcaggga tatttaggtt ttgtagtaat tgagaggcct
    25801 cactttcagc ctcccagccg cctagctcag caaagcttcc ttctaattcg gcagcgcgaa
    25861 caccatcttc ctcagaaaaa tcaggcttca tgtaaatagc atccttttcc ttcatgatac
    25921 tgtaaagctg ttcatttccc atgataacca catcaatggc acgttcctct tcgtaatcaa
    25981 aatgattttg gcgaaggaca gaaagacgct catctggtcc taaagagata tgacctgttg
    26041 ttggttcgat atcacctgcg agaattttta ggaaggttga ttttccggca ccattggcac
    26101 caattaagcc ataagtgttg ccagctgtaa atttgatatt aacatcgtca aaaagttttc
    26161 gatcactaaa gcgcagtgat acgtcagaaa ctgttagcaa tttgtcacct cattttattt
    26221 atctaatcct cattgtacct aaaaaagccc cttttttcaa tcagaaaagg gcttagggct
    26281 tacataggca gcagcacatc tttgtcctct agtttgtaat gcttggttaa gctgaagcca
    26341 cgtcccatga cctgtgctgc tggcatgaca acgataaagg cagtgtcatc gatttctaga
    26401 attttttcct gtaaagctgg caactcatag ccagaaacaa tggccattag catgatcttg
    26461 tctgatgttg tgtagcctcc tcggatagga atcttagaga caccacgatc cataacacct
    26521 gtaatataag ccttgatggc ctgatattcc tttgaaataa tcatgacatt cttagaagag
    26581 tcaaagccat tttccatgac actaatgaca tagccaataa cgagcagtcc gatcgtagaa
    26641 tacatgacat catcagcaga taaagcgatg aatcccatta aaacactaat gccatccaca
    26701 atagtcatag caactcccaa tgataatgga gaatatttgt gtaggatttg tgtcagaata
    26761 ccagtacctc cggttgatga atttccccaa aagaccattc caaggccgat cccacaaatg
    26821 atgccaccaa aaatagctgc taataattgg ttatgagtga gtgttggaag ctggctggtt
    26881 aggcgtatag caatagggta aatccatgaa ccgtagaggg ttttgatgag attttgttta
    26941 ccaagaaaga agtagcataa aatcaataaa gggatattgc ttagcattaa aaagagcgag
    27001 gggctaattc caaacagcgc tttgataaca actgaaatcc ccaccatacc acctgaagca
    27061 atattattat caacaaacat tgtgttaaag ccgatagctg tgatgaagga accaatggtt
    27121 acaaatagta aatccattac cctttttttc atatttaata cctcctttat cgtttagtaa
    27181 acataataga cccattatct cctaaaagaa tagaaaccgt caagccctat tgcttaaaaa
    27241 tcttagcagc ttgacaaatc acttaaaatg tcatagaatg accctaaact agatgagtaa
    27301 tctttccctt gtttttagag agctagtggt tggtgagagc tagcagcaag caagatgaaa
    27361 tgggctagtg gatcttttga gaggaaacca taactttcag gcctggcacc ccttatcgtg
    27421 caatttcttg agttgagaag atgagatagt attgattgat cagagatact aattgaggtg
    27481 gtaccgcgta tttattgtaa tgacgccctc acgcaagcct tttgcgtgag ggtttttgat
    27541 gtcataaaat cagtattaag gagaaatcat gacaaaacca gttattttaa caggagatag
    27601 accaacagga aagctacact tgggacatta cgtcggcagt cttaaaaatc gtgtaagcct
    27661 gcaaaatgaa aacaagtaca agatgtttgt ctttttggca gatcagcagg ccttgacgga
    27721 tcacgccaaa gaatctgaga tgattcgtga gtctattttc aatgtcgcat tggattatct
    27781 ttctgtcggc ttggatccaa gtaagtcaac tatttttatc caaagtcagg ttcctgaact
    27841 tgcagagtta acaatgtact atatgaattt ggtgtctctt gctcgcttgg agcgtaatcc
    27901 aaccgttaaa actgaaattg ctcaaaaggg ctttggtgag agtattccag caggcttttt
    27961 ggtttaccca atttctcaag ctgctgatat cacagccttc aaagctaatg tagttcctgt
    28021 tggtaatgat caaaggccaa tgattgagca gacacgtgaa attgtaagaa gctttaatca
    28081 tacctataag acagcctgct tgattgagcc agaaggtctt tacccagaaa atgaaaaggc
    28141 aggacgtcta ccagggcttg atggcaatgc taaaatgtcc aaatcactgg gtaacggcat
    28201 ctatctttct gatgatgctg acactgttcg tcaaaaagtc atgagtatgt ataccgatcc
    28261 aaatcatatt cggattgagg atccgggaca gctagaaggt aatatggtct ttcattacct
    28321 agatattttt ggccaaaaag aggacaaagc tgatattgaa gcgatgaaag agcattacca
    28381 aagaggtggc cttggagatg ttaaaaccaa gcgttatctg ctggatattt tggaaagaga
    28441 gcttgcgcca attcgccaac gccgattgga atacgccaag gataagggcg aggtctttcg
    28501 tatgctagaa gcaggaagtc aaaaagcaca ggcagtggct gcccaaacat tgtctgaagt
    28561 aaaggttgct atggggattc gttattttta atagcgtaga ggctgagaat gattcttggc
    28621 ctcttatctt ttcaaatgca cctatcactc atgagtcaaa acctgtcttt ttaatttaca
    28681 gaaatatata gaattatgtt attgacaaat gaatttagcg tgatatgata gtaacaataa
    28741 aaataggctg gggtaatatt ccctaaaaaa gaagaaaaga ggattgtgtt aatgtcaaat
    28801 tgggacacta aatttttgaa aaaaggctac acgtttgatg atgttttgct tattccggca
    28861 gaaagtcatg ttcttccaaa tgaagtcaat ttaaaaacca agcttgctaa aaatttgaca
    28921 ttaaatattc ctattattac cgcagccatg gacactgtaa cagacagtaa aatggctatt
    28981 gcgattgcgc gtgcaggtgg tcttggtgtt attcataaaa acatgtcaat tgctgagcag
    29041 gctgaggagg tgcgtaaggt caagcgctct gaaaatggtg tcatcattga tccgtttttc
    29101 ctaacgcctg agcacaaggt agctgaggct gaggaattaa tgcagcgcta ccgtattagt
    29161 ggtgttccga ttgtagagac cttagctaac cgcaaattag tcgggattat tactaatcgt
    29221 gacatgcgtt ttatttctga ttacaacgcc ccgatctcag aacatatgac aagtgagcag
    29281 ctggtgacag ctgaggttgg gactgacctt gagacagcag agcgtatcct tcatgagcat
    29341 cggattgaaa agctaccatt ggtagatgat aatggccgtc tttcaggttt gattacaatc
    29401 aaggatattg aaaaggttat tgagtttcca catgctgcaa aggacgagtt tgggcggttg
    29461 ctggtagcgg ctgcggttgg tgttacatca gatacctttg agcgtgcaga ggctttattt
    29521 gaagctggtg cagatgctat tgttattgat acagctcatg gacattccgc aggtgttctt
    29581 agaaaaattg cggagattcg cgcccacttc cctgataaaa ccttgattgc aggaaatatt
    29641 gctactgctg aaggcgcgcg tgccctttat gacgcagggg ttgatgtggt taaggttggt
    29701 atcggaccag gctcaatttg tacaactcgt gtcattgctg gtgttggggt acctcaagtt
    29761 acagctattt atgacgcagc tgctgttgct cgtgaatatg gcaaaaccat tattgctgat
    29821 ggtggtatta agtattcagg agacattgta aaagcccttg cagcaggcgg caatgctgtc
    29881 atgttaggct ctatgtttgc tgggacagat gaagctccag gtgagactga aatttaccaa
    29941 ggacgcaagt ttaaaactta tcgtggcatg ggatcaattg cagctatgaa aaaaggatca
    30001 agcgaccgtt acttccaagg ctctgttaat gaagccaaca agctagtgcc agaaggtatt
    30061 gaaggacgtg ttgcttataa gggagctgcc tctgatattg tctttcaaat gcttggtggt
    30121 attcgctcag gtatgggata tgttggagct ggtactatcc gagaattgca tgacaatgct
    30181 caatttgtag agatgtcagg agctggtctg attgaaagtc acccacatga tgtccaaatc
    30241 acaaatgaag caccaaatta ttccatgcat taatcctgca ggtgtttact tgatgtagta
    30301 tttgacatat ctattttaaa agctgagata ttttctcggc tttttttgtt gcacgattaa
    30361 accatgatta gaaatgacag cttgctagcc ctagctattt gctttttagc tttgtgatat
    30421 ttcaatgcta ggctaatgat caaatcatac tgaatgctct taagcgtaat accttccaaa
    30481 aatggcataa ccctaaaagg attaacttaa atagacatga aatattgtga aatatagaaa
    30541 tcatgttaaa ataatattat taaatagtta aattaaaaag aaatatacca aaatgattcc
    30601 atttattttt gggaatttat cgataagtat aggaatgata taggagtata gacatgaata
    30661 ggtttttaaa gatcagtctg cttattgttg gtgttattgt cattatgctt ggcatggaag
    30721 taaagcatag aatggatata tacgatcaaa tcaagcagga ggagataaaa attgcccaaa
    30781 gtaaagaagc aattgtgatt tatgaacagg agttaaaatg gttggaccca aatgcattga
    30841 caaatgaagg gactattaaa tcctattcta ttgatttaga ctcaataact cttaatccaa
    30901 tgggaggctt ttccattgct ttacatataa acaaaaatcc aaagtataag tatcgaataa
    30961 gtttaatgtg gaatacacca atgagagatt tatgtgtggg aggatcctct ttgtcgccag
    31021 aattacaaga attgttagat aggtaatgat tatgacaggc tatcagaaac aattgattgc
    31081 accaaagaac aatataattt tcatgaaaag gagcatagtt atgaaaacat tgttaaaact
    31141 cattgtattt attgttggta ctcttgtact tatgcttggc atggaggtaa agcatagaat
    31201 ggatacatac gatcaaatca aacaggtaga gctcaaaaac gcgcatagta aagaagtgat
    31261 tgaaatgtat gaacaggagc taatatcaat ggatccccag gccctaacag atgaaggact
    31321 tatcaagtcc tacactatcg actcagattc actctttatt aatccgatgg gaggcttttc
    31381 cattcattta attatcaatg atgatccaga tatttacttg agagttggcc ttggtagata
    31441 tgatatggaa agaaatttgg agattgatgg tatctatcgc tcagaaaagt tagaaaaact
    31501 actaaaagga gtggagagat gaaaacattg ttaaaactta ttgtatttat tgttggtgcc
    31561 cttgtactta ttcttggcat ggaggtaaag catagaatgg atatatacga tcaagtcaaa
    31621 caggtagaac tcaaaaacgc gcatagtaaa gaagcgatag acatttatga aaagaagtta
    31681 aaaagattgg atcctcaggc cctaacagat gaagggctta tcaagtctta tactattgac
    31741 tcagactcaa
//
LOCUS       DARYYD010000024        31389 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.024, whole genome shotgun sequence.
ACCESSION   DARYYD010000024 DARYYD010000000
VERSION     DARYYD010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31389
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.024"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..174
                     /locus_tag="TV188_000994"
     CDS             <1..174
                     /locus_tag="TV188_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1534362.1"
                     /translation="EAKKPEQPKPMTKPGAKKPEQSLPSTGDIRNPFFTPAAIAIMIA
                     AGTIAIPKRKEED"
     gene            complement(420..734)
                     /gene="trxA"
                     /locus_tag="TV188_000995"
     CDS             complement(420..734)
                     /gene="trxA"
                     /locus_tag="TV188_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002263363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEL1534363.1"
                     /translation="MAHIVTDATFEAETNEGLVLVDFWATWCGPCLMQAPILDQLAAE
                     IDEAELKIVKLDVDDNPNTAQQFGIMSIPTLLFKKDGKVVKQVAGVHTKDQIKAIVAE
                     LS"
     gene            914..2233
                     /locus_tag="TV188_000996"
     CDS             914..2233
                     /locus_tag="TV188_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEL1534364.1"
                     /translation="MEAYELIVIGFGKAGKTLAAKMAQLGKRVALIEQSPTMYGGTCI
                     NIGCIPTKALITAAEHNASFADAMAHKDTVVHRLRQKNEQLLAQSGVTLYNGKASFVS
                     NKTIQVEAGQERILLEGKHIVINTGAVSNRFPIPGLADSQHVVDSTGILALTEQPQRL
                     AIIGAGNIGLEVASLYASLGSEVTMYEAAPAILGRYEPVVAELAQDYLEKAGVTFKLS
                     ATVELIANDEAGRVLVTANGKTEAFDCLLYAMGRKPATQGLGLENTDIKLDDRYAVVV
                     DDYCQTTVEGLYAVGDVNGGPQFTYTSLDDFRIVFGQLTGTSQYNHKDRGYLPTTVFI
                     EPPLSQIGLTEKEAKEQGLPYKANELLVANMPRAHVNNDLRGIFKVIVNTETNEILGA
                     TLFANNSHEYINLIKMAMDNQIPYTYLKNQLFTHPSMAENLNDVFNL"
     gene            complement(2573..4909)
                     /locus_tag="TV188_000997"
     CDS             complement(2573..4909)
                     /locus_tag="TV188_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEL1534365.1"
                     /translation="MEKKILEQLEFEKVKEQFWPYLQTEQGQLELDLLEPIANKDKIQ
                     AYFTELEEMAAIFVEHHHFALGGLSDVSESMQRLDLEADLSIQELLAVKKLLQVSAEV
                     CRFYADLENVDLVALKALFEKIESFPSLQGSLQAINDAGFVEGFASPELESIRRQISN
                     KEHASRQLLQDILKKQAAYLSESLIASRNGRSVLPVKNTYRHKVAGVVHDMSASGSTV
                     YIEPRALVSLNEELTQLQTDERHEIGRILHELSEQLRPHSRSLRNNAWLLGHLDLVRA
                     KYLYMQAKQATVPVISDDKSLQLLNARHPLIQNPVANDLHFANDLAVIVITGPNTGGK
                     TIMLKTLGLAQVMAQSGLPILADKGSRVAVFNGIYADIGDEQSIEQSLSTFSSHMTHI
                     VEILNQADSDSLILFDELGAGTDPQEGASLAMAILEQLRLTNIKTMATTHYPELKAYG
                     IEIAYVENASMAFDNVSLKPTYRFMQGVPGRSNAFDIARRLGLAEHIVKEAQAMTATD
                     HDVNRIIEQLEQQTLESRKRLEHIKEVEQDNLKFNRAVKKLYNEFSHAKDKELEKAAL
                     EAREIVDIALAESDSILSQLHEKAELKPHEIIEAKHRLKQLAPEQSLSQNKVLKKAKK
                     WRAPRVGDDIIVTAYGQRGTLLAQLKDKRWEAQVGLIKLTLKEDEFSLVKLKEEAQQP
                     KKRAVKVVKKAATGKGPRARLDLRGKRYEEAMQELDAFIDQALLNNMSQVDIIHGIGT
                     GVIREAVGKYLRRNKHVKSFGYAPQNAGGSGCTIANLG"
     gene            complement(4982..5527)
                     /locus_tag="TV188_000998"
     CDS             complement(4982..5527)
                     /locus_tag="TV188_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEL1534366.1"
                     /translation="MLSVLILLLLSWSFYIGYNRGLILQTFYCFGALVSLLFAHHGYK
                     ALAGKLALWVPYSNPAEGAATLFFKDINIFELDKVYYAGIAFFILSTVGYAVVRLAGV
                     LVHLAPVDYFDGFEAKLASGLLAVMVSVLFLSMALTVLATIPMPFIQGRLHGSLLSRL
                     LVEHCPFISSILRQLWVTAIL"
     gene            complement(5527..5838)
                     /locus_tag="TV188_000999"
     CDS             complement(5527..5838)
                     /locus_tag="TV188_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534367.1"
                     /translation="MKNINRYKLTFGEKTLTLTTDKDNLFMEEVDRVAKEKYQAIKER
                     LPEADDETVAILMTINTLSAQLSREIEIEKIEAEIVELREKALAGIQEKASQADTDEV
                     S"
     gene            5956..6864
                     /locus_tag="TV188_001000"
     CDS             5956..6864
                     /locus_tag="TV188_001000"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEL1534368.1"
                     /translation="MDTLVFKINSQVSSSLIKQLAPYRISNANPYVRLAAKKDGVTLM
                     LYTSGKLVLQGRQAAKLAQELDLQETPADQRPAPSSAQDIPLIGSDEVGNGSYFGGIA
                     VVASFVQPEEHALLRQLGVDDSKNLNDKSIAQIAPVLKKHIQHRALLLSPKKYNEMVG
                     KGKPYNAVSVKVALHNQAIFLLLNDGARPEKIVIDAFTSQANYDKYLQQEKNHFRNPL
                     TFEEKAEGKYLAVAVSSIIARQLFLDNLDKLSQDLGYRLPSGAGRPSDQIASQILAAY
                     GMAGLEHCAKLHFANTKKAQALLKKQ"
     gene            6889..7488
                     /gene="lepB"
                     /locus_tag="TV188_001001"
     CDS             6889..7488
                     /gene="lepB"
                     /locus_tag="TV188_001001"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1534369.1"
                     /translation="MKQFIKEWGAFTLFILLFGLSRLFLWQPVKVDGHSMDPTLAHGE
                     RLIIFNKAKIDRFDIVVASEEDENGQRKEIVKRVVGMPGDKLSYRNDTLYINNKKTKE
                     PYLDTYLTSFKKDKLQSTYAYSDLFQELAENAAAFTVNSEGKTEFDITVPKGEYFLLG
                     DDRIVSRDSREVGSFKKQDIVGEVKFRFWPLNKINLFPR"
     gene            7717..10116
                     /locus_tag="TV188_001002"
     CDS             7717..10116
                     /locus_tag="TV188_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEL1534370.1"
                     /translation="MEHFFTGTVDRIIFDNASNFFKILLLAIEDTDSDFDEADIVITG
                     TMAEIIEGEAYTFWGELTQHPRYGQQLRLSRYQKAKPTSAGLVSYFSSEHFKGIGQKT
                     AEKIIALYGNNPIDEILKNPSRLNEISSLSKANREAFVAKLKANYGTEQVIAALADLG
                     LANRFAFQLFDKYKEEAVHIVKDNPYQLIEDIQGFGFKLADSLAEQLGIESASPKRFR
                     AALLHCLLEQSIKRGDTYIQARELLALTISLLEDTRPVECDPAIVANQLTQLIDEGKV
                     MTIGTRVFDSSLYYAEDGIQKHLTRLLQQPLTKEPSQDTIDQEIQAIQEELAITYDKI
                     QKQAISQALTSKVFILTGGPGTGKTTVIRGILQAYASLYQIDLKQKDIPIILAAPTGR
                     AARRMNELTGLASATIHRHLGLNGDNDYQAMEDYLDCDLLIVDEFSMVDTWLANQLLT
                     AINSNTQLIIVGDSDQLPSVGPGQVLADLLKVDRIPHITLDKIFRQSEESTIVDLANH
                     IRQGILAPDFCQKKADRSYFEAQAPFIPGMMTKIVQAALKSGIPAEEIQILAPMYKGL
                     AGINSLNQLMQNLLNPLANQTEFLFNETAFRKGDKVLHLVNDAQLNVFNGDIGYITDL
                     IPAKYTESKQDEIIMDFDGTEIVYPRNEWLKITLAYAMSIHKSQGSEFQVVILPVTRQ
                     SGRLLQRNLIYTAITRSKSKLIMLGEIAAFEEAIKKEGDKRHTYLVQRLQVAEADDHT
                     AAASVKESNQSSLSVMPATSPQKEQEQPPYLLTPHNFLAIDPMIGLTEDDMLTFFKKK
                     S"
     gene            10212..10697
                     /locus_tag="TV188_001003"
     CDS             10212..10697
                     /locus_tag="TV188_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534371.1"
                     /translation="MISYEQVRQALRTSTITIIIINAISMVITLFGLAGIFFLKSQLD
                     KPEFRAQFSAEQLRLFEVGISPFTIFMSVISLGLVVLTTVLCGFNLSKIKQGSTVSYV
                     PYIIGIVLYLISIVSQLFSQIEPVSMIIVLAELALYGFAFYKAKTLNEKDKDNPQSIE
                     E"
     gene            complement(10840..11943)
                     /gene="dinB"
                     /locus_tag="TV188_001004"
     CDS             complement(10840..11943)
                     /gene="dinB"
                     /locus_tag="TV188_001004"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEL1534372.1"
                     /translation="MLIFPLINDTSRKIIHIDMDAFFAAVEERDNPELKGKPVVIGKN
                     PRESGGRGVVSTCNYEARRFGIHSAMSSKEAYERCPQAIFISGDHAKYRRIGYDIREI
                     FKRYTDQVEPVSIDEAYLDVTTNKLGIKSALKIARLIQHDIWNSLQLTCSAGVSYNKF
                     LAKLASDFEKPHGLTLVLPDDALPFLEKLPIEKFHGVGKRTVERLHEMGIYTGQDLLR
                     VPEMTLIDQFGRFGYELYRKARGISHSPVKPNRMRKSISSERTYAKLLYQEADIKAEL
                     SKHARRVADLLEANKKLGRIIVLKVRYADFTTLTKRVSLPELTRDARIIDQVARELFD
                     SLEEHQAGIRLLGVTMTGLKDKVTDILLDLSFN"
     gene            12152..14476
                     /gene="pflB"
                     /locus_tag="TV188_001005"
     CDS             12152..14476
                     /gene="pflB"
                     /locus_tag="TV188_001005"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEL1534373.1"
                     /translation="MATVKTNADVFEKAWEGFKGTDWKEKASISRFVQANYTPYDGDE
                     SFLAGVTERSLHIKKVIEETKAHYEATRFPYDTRPTSIADIPAGFIDKDKELIFGIQN
                     DELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKHVTTVNDGIFRAYTSNIRRA
                     RHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAITEIDEESIRLREEI
                     NLQYQALGEVVKLGDLYGVDVRRPAENVKEAIQWVNIAFMAVCRVINGAATSLGRVPI
                     VLDIFAERDLARGTFTESEIQEFVDDFVLKLRTVKFARTKAYDALYSGDPTFITTSMA
                     GMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYAFRRYCMHMSHKHSSI
                     QYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNGGY
                     DDVHKDYKVFDIDPVTDDVLDFDTVKANFEKSLDWLTDTYVDALNIIHYMTDKYNYEA
                     VQMAFLPSHQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYPRW
                     GEDDPRSNELAEWLIEAYTTRLRSHKLYKNAEATVSLLTITSNVAYSKQTGNSPVHRG
                     VYLNEDGTTNLSQLEFFSPGANPSNKAKGGWLQNLNSLASLDFSYAADGISLTTQVSP
                     RALGKTHDEQVENLVTILDGYFENGGQHVNLNVMDLNDVYDKIMAGEDVIVRISGYCV
                     NTKYLTPEQKTELTQRVFHEVLSMDDAAEAISGK"
     gene            14779..15057
                     /locus_tag="TV188_001006"
     CDS             14779..15057
                     /locus_tag="TV188_001006"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534374.1"
                     /translation="MKRLKTLCLLATAITLTLAPISTSQTTTQTVYASETHQNLCTNT
                     GNGWFKCPDGHGGWTWHFDENHKSNQQSFLGGLLGFALSLWGAIIRLF"
     gene            complement(15221..16162)
                     /locus_tag="TV188_001007"
     CDS             complement(15221..16162)
                     /locus_tag="TV188_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEL1534375.1"
                     /translation="MTLEVIEKVSQQIQEGLYHGASLALFRCGGWQEHYIGTLDGQRP
                     VTKGLVYDLASVSKVVGVATVCIAMINSGALALDTPLRHYYPDAQKLEVTLRQLLTHT
                     SGLDPYIPNRDQLNAQQLRAAMHQLQVKDDKTFHYTDVNFLLLGFMLEHLHGKSLDEL
                     FQEMVFTPFGMTETSFGPRPEAVPTVKGVLDGEVHDPKAKVLGNHAGSAGLFSTIRDL
                     ERFIEHYLKESFSDRLFQSYSRQEKPRSLGWSLEGDWISHTGYTGPFIMLNKKEQQAA
                     IFLTNRTYDKDDRALWIKERRQLRDAIHRTFDRNSPR"
     gene            complement(16159..16914)
                     /locus_tag="TV188_001008"
     CDS             complement(16159..16914)
                     /locus_tag="TV188_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEL1534376.1"
                     /translation="MTLFDNIVFKTPVLRVNNRDLNIAFYQKNLGLRLVSEENAISIF
                     SSWGQGQERFVIEESPAARTRVVDGPKKVNTIVIKTTAPKDIEQLLAHGVDYDLIFKG
                     KKGYAFEVTSPEGDRFLLHAEDDIKELDIVDDVPAIDKEADFRGLSQFSFDLIVLNVL
                     DDEQSRAFYQSIFGDCLPVTLEFNREAGQDLTIVPHVTWDLEILEFQVSDSYDLLALK
                     TYLEDKGCQVYLDKKARVLVLSDPSQIEIWFVK"
     gene            complement(17407..18255)
                     /locus_tag="TV188_001009"
     CDS             complement(17407..18255)
                     /locus_tag="TV188_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEL1534377.1"
                     /translation="MEITWTVKYITEFIATAFLIILGNGAVANVDLKGTKGNRSGWLV
                     IAFGYGLGVMMPALMFGNVSGNHINPAFTFGLAVSGLFPWAHVLQYVLAQLLGAMFGQ
                     LVVVAVYKPYFVQTDNPNNILGSFSTISAVDDGDKGSRKAAYINGFLNEFVGSFVLFF
                     GAMALTKNYFGVELVGKLVEAGYDQTTAATQISPYVTGSLAVAHLGIGFLVMTLVTSL
                     GGPTGPALNPARDLGPRLVHHFLPKSVLGQAKGDSKWWYSWVPVAAPVLAAVAAVAAF
                     KFLYIK"
     gene            complement(18357..18809)
                     /locus_tag="TV188_001010"
     CDS             complement(18357..18809)
                     /locus_tag="TV188_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1534378.1"
                     /translation="MISKYKRILAAVDGSYESELAVEKAINVALRNDAVLLLAHVIDV
                     KAYQGDAMVSDYVFDTQEEHAKEVLRYYEKMARGRGVSSIKKIIERGNPKKLLASDIP
                     EKEQADLIMVGATGLNTFERLLIGSTSEYILRHAKKDLLVVRNCEKTL"
     gene            complement(18829..20028)
                     /locus_tag="TV188_001011"
     CDS             complement(18829..20028)
                     /locus_tag="TV188_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1534379.1"
                     /translation="MEDKLFNKHFIGITVLNFIVYMVYYLFTVIIAFVATKELGAKTS
                     EAGLATGIYILGTLLARLIFGKQLEVFGRRLVLRGGAIFYLLTTLAYFFMPTIGMMYF
                     VRLFNGFGYGVVSTATNTIVTAYIPASKRGEGINFYGLSTSLAAAIGPFVGTFMLDNL
                     HIDFRMIIILCSVLIAVVVLGAFAFPVTDIALNSEQLAKTKSWTVDSFIERKALFITL
                     IAFLMGIAYASVLGFQKLYTTDIHLTTVGAYFFVVYALIITITRPAMGRLMDVKGEQW
                     VLYPSYLFLALGLFLLGSVTSSLPYLLSGALIGFGYGTFMSCGQAASIKGVEEHRFNT
                     AMSTYMIGLDLGLGAGPYLLGLIKDMLLGSGVQSFHQLFWLAGLIPAACAVMYFLKTQ
                     AKAIDKG"
     gene            20197..20856
                     /locus_tag="TV188_001012"
     CDS             20197..20856
                     /locus_tag="TV188_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1534380.1"
                     /translation="MNHQILQRYIDSHNFPIIEKGYHKYLTFESLEEDFTYILKEGIV
                     KQSVLSKYGMEFNLRYVTGLEITSVLNTGYSKDMREPYNVRIESETASFYKVRHSTFL
                     RDISEDIELQGYVKDFYHYRLQKSMKKMQCMLTNGRIGAISTQIYDLMTLFGRPLANG
                     HILIDFIITNEELGKFCGISTASSVSRLLKQLKKEGIIQINDQHIIITNLEKLKDNIV
                     F"
     gene            20877..23162
                     /locus_tag="TV188_001013"
     CDS             20877..23162
                     /locus_tag="TV188_001013"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEL1534381.1"
                     /translation="MRYNQLSYIPTSLETAVAELQALGFAVQQEQAPKENFAIFLRKL
                     FFHFQDTDYPLNHMIASKDLDLLTFLTSDATLTKEVFDLVALQVLGFIPAVDFTDAQD
                     FIQKIGFPIVFDSQQLLLNLHQLLATRQKSGVTLIDSLVSQGLLPMDNCYHYFNGKAL
                     ATFDTTSLIREVVYVEAPLDTDQDGQLDLIKVNIIRPKASTAIPSMMTASPYHQGINE
                     TANDKKLHRMEGELSPKAPRRITVEPTDFQPLATKPSRLPVNECQETFSHISSYTLND
                     YFLARGFANLYVSGVGTAGSTGFMTSGDYAQIESFKAVIDWLNGRATAYTSHKRDYQI
                     KADWSNGLVATTGKSYLGTMSTGLATTGVDGLAVIIAEAAISSWYDYYRENGLVCSPG
                     GYPGEDLDVLTELTYSRNLLPGDYLRHNDHYQQLLSQQSQALERQSGNYNQFWHDRNY
                     LPQADRIKCEVVYTHGLQDWNVKPRQVYNIFNALPDSLGKHLFLHHGEHVYMHNWQSI
                     DFREAMNALLCQKMLGQNNGFTLPTIIWQDNQKEQTWKELTAFGGHSKRQIALGDDHV
                     LIDNHYGEEDFKRYSKDFRAFKAELFEGKANQAVIDILLEEDLPINGQACLKLKLKSS
                     ENKGILAAQLLDYGKKKRFADIPAILELDSIDNGQQFAREALKELPFKDSPYRVVTKG
                     VLNLQHRSDLLTIEDIPNDQWMTITFHLQPTIYHMAKGDTLRVVLYTTDFEHTIRDNS
                     NYALTLDLEQSYLLIPTDEEE"
     gene            complement(23268..23660)
                     /locus_tag="TV188_001014"
     CDS             complement(23268..23660)
                     /locus_tag="TV188_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HEL1534382.1"
                     /translation="MLTEEMKEMIAEQLAMVVTVDNEGNPNIGPKRSMRLLDDETLVY
                     NENTGGQTCSNIQANGKIEVAYVNREQLRGYRFVGRAEIITEGPVFEAAKEWAEGKMG
                     APKAAGLIHIESVYSLHSGAEAGKKVSK"
     gene            complement(23814..24071)
                     /locus_tag="TV188_001015"
     CDS             complement(23814..24071)
                     /locus_tag="TV188_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1534383.1"
                     /translation="MSKATLKELRIAQKKTQKELSALTGISVRTLARYEKDVQKLRRA
                     KYEKLRGIAEALTISVDDIFFGRRFGFYEIKSACLLIAFLL"
     gene            24250..24624
                     /locus_tag="TV188_001016"
                     /pseudo
     CDS             24250..24624
                     /locus_tag="TV188_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678526.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(24882..25664)
                     /locus_tag="TV188_001017"
                     /pseudo
     CDS             complement(24882..25664)
                     /locus_tag="TV188_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514970.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
     gene            complement(26181..27689)
                     /locus_tag="TV188_001018"
     CDS             complement(26181..27689)
                     /locus_tag="TV188_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1534384.1"
                     /translation="MLEEYLEPVINHQALLLTILLGKKRISFHAIQQKTGFSLANIKR
                     YIHQLEELFQGDIAFEWDSTIVRCTVLKRGKPFLKTIYRQSVRLHILKFLLIKAPCYK
                     VKSVSGFAREHFISTPSAYRLIQHMKPFVEECGLALEDNSVVGEEWRIRYLIALLHDK
                     YGIVIYELTDHDLDIVHDFIFSIKKQQTPHPLLDKKFRFFDVLLSLSWKRGEFDVAIP
                     QEGIFKRLKSLALYGYLEDFFKREGKLLLDMDFPSSEIDYIFLVYLTVNNSFSITQWS
                     EEDSSALLTIIQEDPAYQELLGELRQLFGHYIAFDKACIQTLIPYFRKTLFDLSLFIP
                     QKYYYAEEYQGSKLLANRIELMINSWAERVSGVGRLTGSNLHLLCTRLEQLVREGLPP
                     LAIAVIEINKKNIDILYSLVMQQVSPCVAKVYRFNILSEAELPWRTDFDLIVTTAEMT
                     AFIEERLSLNENTKILDFNFDFVMYQAEYLSQVIRELRDKQYQEALDTILNG"
     gene            27940..28836
                     /locus_tag="TV188_001019"
     CDS             27940..28836
                     /locus_tag="TV188_001019"
                     /inference="COORDINATES: protein motif:HMM:NF012162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioester-forming surface-anchored protein"
                     /protein_id="HEL1534385.1"
                     /translation="MKTKSFRKVLTTSATCIVLATSFAGGTLRVWAEQLYYGWNDGTR
                     QSSPYFLYVSPKNAPKRELKDEYVVYCFNKKLYWPDQWESIYSNFNDIRSPYNDLPVY
                     EKKLGYDGIFKQYAPDYKKDISDIASALVAVLSNGYPTNKSQLSTSYHLNNDSSRKVT
                     QLAIWYFSDSLTKEYLKDTGGYNLNDMEKKALDFLISKGEDSKLKSEQSNYSLDIYVY
                     QSGGHDHMKDYQNLLGSTLIPKEPLKPQLGGFSGHNGNGLSGLEGGSSGSQETNEDGK
                     KGLIGFHGGLSGSEGKRDPFQD"
     gene            28833..29096
                     /locus_tag="TV188_001020"
     CDS             28833..29096
                     /locus_tag="TV188_001020"
                     /inference="COORDINATES: protein motif:HMM:NF014980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein"
                     /protein_id="HEL1534386.1"
                     /translation="MKGEAGAPDTPQKPNDPLQSLEGGNSPIVEQNYGSTEGYHGQSG
                     ILEETEDTNPPGIILGGSGNVETRSSSDGAWRWSSWRIRRNDT"
     gene            29023..29829
                     /locus_tag="TV188_001021"
     CDS             29023..29829
                     /locus_tag="TV188_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin binding protein"
                     /protein_id="HEL1534387.1"
                     /translation="MSKRDPHLMGLGGGLAGESGETTPKPGQTGGHGPIIETTEDTQK
                     GMSGQSGGTIESENTKKPEVMIGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVM
                     IGGQGQTIETTEDTQKGMSGQSGGTIESEDTKKPEVMIGGQGQIIDFSENTQSGMSGQ
                     SGDTTVIEDTKKSEIIIGGQGQIIDFSEDTQPGMSGQSGGTTIVEDTKKPTPKPKPAP
                     APIVNDEKPNKGTQLPQTNDMKQLTLSIIGAMSMLLVLCLSLFKRPSKKD"
     gene            complement(30201..31247)
                     /locus_tag="TV188_001022"
     CDS             complement(30201..31247)
                     /locus_tag="TV188_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1534388.1"
                     /translation="MRLRTYIVIGYLMSMLITIAGLIVGLNQMLITIEDISYILVIAL
                     IASVAGGIVNMILLSNVFSSLKRLKKKIQAISERNFDSGQLIKCPLEFKDLEEAFNQM
                     SSELKVSFESLSESEHEKSMMIAQLSHDIKTPLTSIQATVEGILDGVIPREEERHYLN
                     TISRQTNRLNQLVEELHMVSLNDQKQDDKQQLQIIYLEKLLIDMLSEFQLTLEQEKRS
                     VHIEVAKEVVKISSRYDALSRIMLNLVSNALKYSKANTALTIHAYQQEQSIRIDVIDQ
                     GQGIKKEDLPLIFKRLYRVEASRNMKTGGHGLGLSIARQLARQLGGDIAVESQLGKGS
                     CFSLLLPASPPLGD"
     gene            complement(31249..>31389)
                     /locus_tag="TV188_001023"
     CDS             complement(31249..>31389)
                     /locus_tag="TV188_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HEL1534389.1"
                     /translation="WEEEYLDDTNTLNVHIHSLRNDLAKYSTEQTPTIKTVWGLGYKL
                     EG"
BASE COUNT         9382 a         7383 c         6252 g         8372 t
ORIGIN      
        1 gaagctaaga agcctgaaca acctaaacca atgactaaac caggagctaa gaagcctgag
       61 caatcacttc catcaactgg tgacatcaga aatccattct tcacgcctgc agctattgct
      121 attatgatcg cagcaggtac cattgccatt ccaaaacgca aggaagaaga ttaaacaaat
      181 taacaatccc catatttcaa caatgataca caagccccta cttgtgtcca cctcaaaagc
      241 agtagccagt cgcgcggcta ctgcttttac tatgcttttt ttacaccagc tctgatagca
      301 gctaataaca aaaaagattg aagacacagc ttattgggtc cccgatcttt ttttggtcat
      361 acaaccaaca gcagctcttg aggcttgctg tccttctaag aggctgttgg cttgttgctt
      421 tagcttaatt ctgctacgat agccttgatt tgatccttgg tatggacgcc tgctacttgc
      481 ttgacaacct taccgtcctt tttgaacagc agggttggga tagacataat gccaaattgt
      541 tgagcagtat tgggattgtc atcaacatct agcttgacaa tcttaagctc agcttcgtca
      601 atttctgctg ctaattgatc aaggattggc gcttgcatta agcaagggcc gcaccaggtt
      661 gcccaaaagt ccacaaggac taggccttca ttagtttctg cttcaaatgt tgcatctgtt
      721 acgatatgtg ccattgtaat ctccgttctt atagtttata agcctatttt aggggaaaac
      781 gactgataat gcaagaatct gatacgaaga cctcggtctt atgatttaag aaaaatctgg
      841 cgtagccatt ttaagacaaa tacgctggcc tttgctacaa tgaccttatc ttaacaacta
      901 aaaggaggct actatggaag catacgagct tattgtgatt ggatttggta aggccggaaa
      961 aactttggct gccaaaatgg cgcagctagg aaaaagagtt gcccttattg agcagagccc
     1021 cactatgtat ggcgggactt gtatcaatat cggctgtatt ccaacaaagg ccttaatcac
     1081 tgctgctgag cataatgcta gctttgcaga cgctatggcg cacaaagata ctgttgttca
     1141 tcgtcttcgc caaaaaaatg agcagctgct agctcagtct ggtgtgacac tttacaacgg
     1201 taaggcaagc tttgtctcta ataagacgat tcaagtagaa gcagggcagg agcggatcct
     1261 cttagagggc aagcatatcg tgatcaatac cggagctgtt tcaaatcgct ttccgatacc
     1321 tggtctagca gatagtcagc atgtggttga tagtacaggg attctagctc tcactgagca
     1381 gcctcagcgc ttggctatta tcggtgcggg gaatatcggg ctagaggttg ccagccttta
     1441 tgccagctta ggcagcgagg ttactatgta tgaggctgca cctgctattt tagggcgcta
     1501 tgagccggtt gtcgctgagc tggcacagga ttacctggaa aaagctgggg ttacctttaa
     1561 gctctctgcg actgttgagc tgattgctaa tgatgaagca ggtagagttc tagtgactgc
     1621 taatggcaag acagaagcct ttgattgtct cctctatgct atgggacgta agcctgccac
     1681 tcaaggcctt ggcttggaaa acactgacat taagcttgat gatcgctatg ctgtcgtggt
     1741 agatgattat tgtcaaacca ctgtcgaggg gctatatgcg gttggtgatg ttaatggcgg
     1801 gcctcaattt acctatacgt ccttagatga tttcaggatt gtgtttgggc agctaacagg
     1861 cacaagccag tacaaccaca aagatcgggg ctatctgcca acaacagtct ttatcgagcc
     1921 gccactttca caaattggtc taacagaaaa agaagcaaaa gagcagggac tgccctacaa
     1981 ggctaatgag ctcttggttg ccaatatgcc acgcgcccat gtcaataacg acctcagggg
     2041 gatttttaag gtcattgtca atacagagac taatgaaatt ctaggggcaa ccttatttgc
     2101 taacaattct cacgaataca ttaacctgat taagatggct atggataacc agattccata
     2161 tacctatctc aaaaaccagc tctttaccca cccgtcaatg gctgaaaatc ttaatgatgt
     2221 ctttaacctt taaaagaacc tcaacctcac ctgcatagca ggtacaacag ccaaactatt
     2281 aaaaaaacaa actccttttt ggctgcttat cacatggata ggcggctagc aaaaggagct
     2341 tgttttttct tgtatccaat cagcaggcta gcagctgctc atggtctaaa ggaactagct
     2401 aggctgggac acgttggtag caaaagtcca gcaagactca ctagctgctg tcatgagctt
     2461 tgaagagcag cacttaggga acacgcccag tagctttctt tgggacgctt ggctcaccta
     2521 gggctcaatc agcttgagta aaaaggggct ttatttgaat caagaggatc aattagccta
     2581 gattagctat ggtacagcct gagccgccag cattttgcgg ggcatagcca aagcttttga
     2641 catgcttgtt gcgtcgcaag tacttgccga ccgcttcacg tataacacct gtaccaatac
     2701 catgtatgat gtcaacctga ctcatgttgt taagcaaggc ttggtcgata aaggcatcta
     2761 gctcctgcat ggcctcctca tagcgcttgc ctcgaaggtc taagcgagcg cgcggccctt
     2821 ttcctgtagc tgcttttttg acgaccttga cagctctctt cttaggctgc tgcgcttctt
     2881 cttttagctt aaccaagctg aattcgtctt ccttgagggt caacttgatc aggccaacct
     2941 gagcctccca cctcttgtcc ttaagctggg caagcaaggt tcctctttgc ccataggcgg
     3001 taacaatgat gtcatcaccc acacgaggag cccgccattt tttcgctttt ttcagcacct
     3061 tattttgcga caggctttgc tctggcgcaa gctgctttag gcgatgcttg gcttcgataa
     3121 tttcgtgcgg ctttagctct gccttttcat gcagctgact taaaatgcta tcactttctg
     3181 ccaaggctat atccacaatc tcacgcgctt caagggctgc cttttccaat tccttgtcct
     3241 tagcgtggga gaactcgtta tagagctttt taacagcacg attgaatttg aggttatcct
     3301 gctcgacctc cttgatatgc tcaaggcgct tgcggctttc taacgtttgc tgctctagtt
     3361 gctcaatgat acgattgaca tcatgatcag ttgcggtcat cgcctgagct tccttgacga
     3421 tgtgctctgc taagcccaat cgtctcgcaa tgtcaaaagc atttgagcga ccaggcactc
     3481 cttgcatgaa gcggtaagta ggctttaggc tgacattgtc aaaggccatg ctggcatttt
     3541 caacataggc tatctcaatc ccataggcct ttagctctgg gtaatgggta gtggccatcg
     3601 tcttaatatt ggtcagacgc agctgctcca aaatagccat agcaaggctg gctccttcct
     3661 gtggatcagt ccctgctcct agctcgtcaa agaggatcaa gctgtcactg tctgcctgat
     3721 tgagaatctc aacaatgtga gtcatatgac tggaaaaggt agacaggctt tgctcaatgg
     3781 attgctcatc tccaatatca gcataaatac cattaaaaac tgccaccctg gagcccttgt
     3841 cagccaaaat aggcagccct gactgggcca tcacctgagc aagccccaag gttttgagca
     3901 tgatggtctt accacctgta ttaggaccgg tgatcacaat tactgctaag tcatttgcaa
     3961 aatgcagatc atttgccaca gggttttgaa tcaaggggtg gcgcgcattg agcagctgta
     4021 agcttttatc gtcagaaatc actggcacag ttgcctgttt ggcttgcata taaaggtatt
     4081 ttgctctcac aagatctaaa tgtcctagta gccaagcgtt attcctaaga gatcgactat
     4141 gcggacgcag ctgctctgac agctcatgca agattcgtcc aatctcatgg cgttcatctg
     4201 tctgtagctg agtcagctcc tcattgagac ttacaagcgc tctaggctca atgtagaccg
     4261 tactgccaga agctgacatg tcatgcacaa cgcctgccac cttatgacga taggtgtttt
     4321 tgacaggcag gacacttcgg ccattacgac tagcaatcag gctctctgac aaataagctg
     4381 cctgtttttt taggatatcc tgcaggagct gacgactggc atgctccttg tttgatatct
     4441 gacgacgaat gctctccaat tcaggactag caaagccttc aacaaagcct gcgtcattaa
     4501 tggcttggag actcccctgt aagctaggaa agctctctat tttttcaaag agtgctttta
     4561 gagcgactaa atcaacattt tccaaatcag cgtaaaaacg acagacctct gccgacacct
     4621 gcaggagctt tttaactgct aaaagctctt gaatgctcag atctgcctct aaatccaaac
     4681 gctgcatgct ttctgagaca tctgatagcc ctcccaaggc aaaatggtgg tgctctacaa
     4741 aaatagccgc catttcctca agctctgtaa agtaagcctg tattttgtct ttattcgcaa
     4801 taggctccaa caagtcaagc tctagctgcc cctgctctgt ctgtaaataa ggccaaaatt
     4861 gctctttaac cttttcaaat tctaactgtt ctaaaatctt tttttccata gttcttatta
     4921 tacctaaaaa tcacttaaaa tgtgggacac taaacaaaaa gagaccagag agactctgac
     4981 ctcaaagaat agctgttacc cataattgcc tgagaatgct tgagataaag ggacaatgct
     5041 caaccaagag gcgagacaaa agactgccat gtaggcgccc ttgaataaag ggcatgggaa
     5101 tggtagcaag aacggtcaat gccatgctta aaaacaaaac cgaaaccatc accgccagca
     5161 agccactggc tagcttagcc tcaaagccat caaaataatc caccggcgca aggtgcacca
     5221 agacacccgc caatcgaacc acagcatagc ctactgtaga cagtataaaa aatgctatcc
     5281 ctgcataata aaccttatcc aattcaaaaa tattaatatc cttaaaaaat aaggtagctg
     5341 ctccctcagc aggattagaa taaggcaccc atagagccag cttgcctgcc agagccttat
     5401 agccatgatg ggcaaacaag agcgacacca aggccccaaa acaataaaag gtctgaagga
     5461 taagccctct attgtagcca atgtaaaagc tccaagaaag cagtaacaat ataagcactg
     5521 agagcatcat gacacctcat ctgtatctgc ttgactagcc ttttcctgaa tacctgccag
     5581 tgccttctca cgcagctcga caatctcagc ttcgattttt tcaatctcaa tctctctact
     5641 cagttgggct gacagggtat tgatggtcat caaaatagca acggtttcgt cgtctgcttc
     5701 tggcagacgc tccttgatgg cctgatattt ttcctttgcc acacgatcaa cctcttccat
     5761 aaagaggttg tctttgtccg ttgtcaatgt taatgtcttc tcaccaaatg ttaatttgta
     5821 acgattaata ttcttcatag gctcacccct ttagcattat accctaaaaa tgacttttcg
     5881 taaaattgtg aaattaatct gagattgcat ggaatgattt cccataacag gacattttat
     5941 gttaaaataa tgttcatgga caccttagtt ttcaaaatca attcccaagt cagcagcagc
     6001 ctgatcaagc agctagcacc ataccgcata agcaatgcca atccttacgt tagactggct
     6061 gccaaaaaag atggtgtcac actgatgctg tatacctcag gcaagctggt gctgcaaggc
     6121 agacaggctg caaagctggc tcaagagctt gatctgcaag aaacgcctgc tgatcagaga
     6181 cccgcaccct ccagcgcaca ggatatcccc ttaattggta gtgatgaggt gggaaatggc
     6241 tcttactttg gaggcattgc tgttgttgct agctttgtgc agccagagga gcacgccttg
     6301 ctcagacagc tcggtgtcga tgattctaaa aacctcaatg ataagagtat cgcccagatc
     6361 gctcctgtcc taaaaaagca tattcaacac agggcgcttt tgctatcgcc taaaaaatac
     6421 aatgaaatgg taggtaaggg gaagccctac aacgctgttt ctgtcaaggt tgctcttcat
     6481 aatcaagcga tttttctgct cttaaacgac ggagcaagac cagaaaaaat tgtcattgat
     6541 gccttcacaa gtcaggccaa ttatgacaaa tacctacagc aagaaaaaaa tcactttcgt
     6601 aatcccttga cctttgagga gaaggccgaa ggcaaatatc tggcagttgc tgtcagctct
     6661 atcattgcta gacagctatt tttagacaat cttgacaagc tcagtcaaga tctgggctac
     6721 cggttgccta gtggtgctgg gcgtccatct gatcagattg ccagtcaaat cttagccgcc
     6781 tatggtatgg caggcttaga gcattgcgct aagctgcact ttgcaaacac caaaaaagcc
     6841 caagcgctac taaaaaaaca ataatcttag aaaaataaag gaaaagtcat gaaacaattt
     6901 attaaagaat ggggagcttt tacccttttt atcctacttt ttggactctc acgtttgttc
     6961 ctatggcagc ctgtcaaggt tgatggccac tcaatggacc caaccctagc acatggcgag
     7021 aggctcatta tcttcaacaa ggctaagatt gatcgctttg atattgttgt tgccagtgag
     7081 gaggacgaga acggacagag aaaagagatt gttaagcgtg ttgttggcat gccaggtgat
     7141 aagctgtctt atagaaatga cactctttat atcaacaaca agaaaacaaa agagccttat
     7201 cttgatacct acctgacgag ttttaaaaag gacaaattac aatcaaccta tgcttacagt
     7261 gatctcttcc aagagctggc tgaaaatgct gctgccttta ccgtcaactc cgaaggaaaa
     7321 acagaatttg acatcactgt tccaaagggc gaatatttcc tactgggtga tgaccgcatt
     7381 gtatctcgtg acagccgcga ggtcggctcc tttaaaaagc aggacatcgt tggtgaggtt
     7441 aagttccgct tttggccact caataaaatc aatctcttcc ctagatagca ggcaagctaa
     7501 agctattttc tagcagggct gatataggct ctatgcccac agcagtaaag actcagggca
     7561 gcaatagcct ctatctatat ctgcttatct atccatacca agaggcttga tgtgctatcc
     7621 aagcactcag ctagctttag agaagcagct attgttgacg ttctaaaacc tgccgttgtg
     7681 caggttttcg actatcttgc acagaaaggt accgtcatgg aacacttttt tacaggcact
     7741 gttgaccgaa ttatctttga caatgcgtca aattttttca aaattctatt actggctata
     7801 gaggatactg atagtgattt tgatgaagct gacattgtca ttacaggcac tatggctgag
     7861 atcatagagg gcgaagccta taccttttgg ggtgagctga cccagcaccc aaggtatggt
     7921 cagcagctgc gcctgagccg ctatcaaaag gctaagccca cctcagcagg tctcgttagc
     7981 tatttttcca gtgagcattt caagggcatt gggcaaaaaa cagctgagaa aatcattgcc
     8041 ctttacggta ataatcctat tgatgagatt ttaaaaaatc ccagtcggct taatgagatc
     8101 tctagccttt ctaaggctaa tcgtgaagcc tttgtggcaa agcttaaagc caattatggc
     8161 actgagcagg tgattgctgc cttggctgat ctaggactgg ccaatcgctt tgcctttcag
     8221 ctatttgaca aatacaagga agaggctgtt catatcgtca aggacaatcc ttatcaactc
     8281 attgaggaca ttcaaggctt tggctttaag ctggctgata gcttagctga acagctagga
     8341 attgagagtg cctctcccaa gcgctttcgt gcggctctgc tgcattgcct gttggagcaa
     8401 tccatcaagc gaggcgacac ctatatccag gcacgtgagc ttttggcgct gaccattagc
     8461 ctattagagg acacaaggcc agtcgaatgc gacccagcta ttgtcgctaa tcagctaacc
     8521 cagctcatcg acgagggcaa ggttatgact attggcacgc gtgtttttga cagcagcctt
     8581 tattatgccg aagacggcat tcaaaagcat ctgacacgct tactacagca gcctctgact
     8641 aaggagccta gtcaagatac cattgaccaa gaaatccaag ccatacaaga ggagcttgct
     8701 ataacctatg acaagatcca aaagcaggcc atcagccagg cactgaccag caaggttttc
     8761 attctaacag gaggcccagg cacaggaaag acaaccgtta tcaggggcat tttacaggcc
     8821 tatgccagcc tgtaccagat tgacctgaaa caaaaggata ttcccattat cctagcagct
     8881 ccaactggtc gagccgctcg tcgtatgaac gaattaaccg gtctagcaag cgcaactatt
     8941 caccgccatc ttgggttaaa cggagacaat gattaccaag caatggagga ttatttagac
     9001 tgtgatttgc tgattgttga tgaattttcc atggttgata cctggctggc caatcagcta
     9061 ttaacagcca tcaattctaa tacccagctg atcatcgtag gagatagcga ccagctgcct
     9121 tctgtcggtc ctggacaggt actagctgac ttgctaaagg ttgatcggat ccctcacatt
     9181 acccttgaca agatttttcg ccaatcagag gagtcaacca ttgttgattt agccaaccac
     9241 atacgccaag gcattcttgc tcctgatttt tgtcagaaaa aggctgatcg ctcctacttt
     9301 gaagcgcaag cgccattcat tcccggcatg atgacaaaga tcgtacaggc tgccctaaaa
     9361 agtggcatcc cagctgagga aattcaaatc ctagccccta tgtacaaagg actagcaggc
     9421 atcaacagcc tcaaccagct catgcaaaac ctcctgaatc ctctagctaa tcagacagaa
     9481 tttctcttta acgagacggc ctttcgtaag ggagacaagg tacttcacct tgtcaatgac
     9541 gctcagctta atgtcttcaa tggtgatatt ggctatatca cagacctcat tccagccaaa
     9601 tataccgaat ccaagcagga cgaaatcatc atggactttg atggcaccga gatcgtctac
     9661 ccaagaaatg aatggttaaa aatcaccctt gcctatgcca tgagcattca caaatctcaa
     9721 ggcagtgaat ttcaggtggt aatcctgcct gtcacccgtc agagtggtcg acttctgcaa
     9781 agaaacctca tctacactgc catcaccaga tcaaaaagca agctcatcat gctcggagaa
     9841 atagccgcct ttgaagaggc aatcaaaaaa gaaggtgaca agcgacacac ctatctcgta
     9901 caaaggcttc aagtggctga agctgatgac catacagcag ctgcttcagt aaaggaatca
     9961 aatcagtcta gcctatctgt aatgccagct accagcccac aaaaggaaca agagcagcct
    10021 ccttatctgc tcacccctca taatttccta gctatagacc ccatgattgg tctaaccgaa
    10081 gatgatatgt taaccttttt taagaaaaaa tcataatata ttaaaaaagt aaggcacaat
    10141 ccttattcct atgctataat atccatgtat catcttaaaa gtacaataac ataacattca
    10201 aggagactta tatgatttca tacgaacaag tacgacaagc actcagaaca tcaactatta
    10261 cgatcattat catcaatgct atcagcatgg ttatcacctt gtttggactt gctggcattt
    10321 tctttttgaa gtctcaattg gataaacctg aatttcgtgc acaattttca gctgagcagc
    10381 taaggctatt tgaggttggc atatcaccct ttactatttt tatgtcagtg attagccttg
    10441 gattggttgt tttgaccact gtgctttgtg gctttaacct ctcaaaaatc aaacaaggtt
    10501 ccactgtcag ctatgttcct tacattatag ggattgtgct ctatcttatt agtatcgtaa
    10561 gccaactatt tagccaaatt gagcctgtct caatgatcat tgtcctagct gagcttgcgc
    10621 tttacggctt tgccttttac aaggctaaaa cccttaatga aaaagacaag gacaatcccc
    10681 aaagcattga agaataagca ggccataaag gtatgataac aagacttcct gtctgccttc
    10741 aaatatggct ctttgtcagc ccactacggt tgacaaagag ccttttttaa ccactaaaaa
    10801 agcaagagga aaattgataa tgtcctcttg ctttttttgt tagttgaatg acaggtccaa
    10861 caaaatatct gtcactttat cctttagtcc ggtcattgtg actcccaata agcggattcc
    10921 tgcctgatgc tcctccaggc tatcaaaaag ctctctagcc acctgatcaa tgatcctagc
    10981 atctcttgtt aactcaggta ggctaacccg cttggtcaag gtcgtaaagt cagcataccg
    11041 aaccttcaaa acaatgatcc ttcctagttt tttattcgcc tcaagcaaat cagcgacccg
    11101 tcttgcatgt ttagaaagct ctgccttaat atcagcctcc tggtagagga gcttagcata
    11161 ggtacgctca ctgctgatgg atttgcgcat acgattaggc ttgactggag aatgactaat
    11221 gcctctggcc tttcgataaa gctcatagcc aaagcgtcca aactgatcaa tcagggtcat
    11281 ctcaggaaca cgcaaaagat cctgcccagt gtaaatcccc atctcatgca gcctttcaac
    11341 tgttcgctta ccaacgccat gaaacttttc aatcggaagc ttttctaaga atggcagagc
    11401 atcatcagga agtactaggg tcagaccatg tggcttttca aaatcactag ctagcttggc
    11461 taaaaatttg ttataagaaa caccagcaga gcaggtcaac tgcaggctat tccaaatatc
    11521 atgctgaatc agtcttgcaa tctttaaggc agacttgatg cccagcttat tggttgtcac
    11581 atctaaataa gcctcatcaa tagacacagg ctccacctga tccgtataac gcttgaaaat
    11641 ctctctgata tcatagccaa tcctacggta cttagcatga tctccagaga taaaaatagc
    11701 ctgaggacaa cgctcgtagg cctcctttga gctcattgca gagtgaatgc caaaccttct
    11761 tgcctcgtag ttacaggttg atacaacgcc ccgtccacca ctttctctag ggttcttgcc
    11821 gatcaccacc ggcttgccct ttaattcggg attatctctt tcttccaccg cagcaaaaaa
    11881 agcatccatg tcaatgtgta taatcttgcg tgaggtgtca ttaatcagcg gaaaaataag
    11941 cataggtccc tccctcctac attatactcc tttaggcttt taaagccaag gcagaggatt
    12001 gtatgacagt tttcaactgt ttcagcaaac tgtaatataa aagaatcttg tatttgtcaa
    12061 gatttttgct tgggaaatcg tttcccctat ggtaaactta gattgtaaat gtaacagatt
    12121 ggacttgtta ctagatttta aggagaaact tatggcaact gttaaaacta acgcagatgt
    12181 ttttgaaaaa gcttgggaag gctttaaggg aactgactgg aaggaaaaag cgagtatatc
    12241 tcgttttgta caggctaact atacacctta tgacggtgat gaatcattcc tagcaggtgt
    12301 tactgagcgt tcattgcaca tcaaaaaggt cattgaggag actaaagctc actacgaagc
    12361 aacacgcttc ccatacgata ctcgtccaac ctcaattgct gacattcctg ccggatttat
    12421 tgacaaggat aaggaattaa tctttggtat ccaaaacgat gagctattca aattgaactt
    12481 catgccaaag ggtggtatcc gtatggcgga aacaactctg aaggaaaacg gctatgagcc
    12541 agatcctgct gtacatgaga ttttcactaa gcatgtgaca acggttaatg acggtatttt
    12601 ccgcgcttac acgtcaaaca ttcgtcgtgc gcgccatgcc cacactgtaa ctggtctgcc
    12661 agatgcttac tcacgtggtc gtatcatcgg tgtttacgca cgtcttgccc tctacggagc
    12721 agattacttg atgcaagaaa aggtcaacga ctggaatgcc atcactgaga tcgacgaaga
    12781 atcaatccgt cttcgcgaag aaatcaacct gcaataccaa gcacttggcg aagtggttaa
    12841 gttaggtgat ctttacggtg ttgacgttcg tcgtcctgct gaaaacgtca aagaagctat
    12901 ccaatgggtt aacattgcct ttatggctgt ttgccgcgtg atcaatggtg ctgctacttc
    12961 tcttggacgt gtcccaatcg ttcttgacat ctttgctgag cgtgaccttg cacgtggaac
    13021 cttcaccgaa tcagaaattc aagaattcgt tgatgatttt gtcctcaagc ttcgtaccgt
    13081 taagtttgct cgtacaaagg cttatgacgc tctttattca ggtgacccaa ccttcatcac
    13141 aacctctatg gctggtatgg gtaatgacgg tcgtcaccgc gttacaaaga tggactaccg
    13201 cttcttaaac acacttgaca atattggtaa ctctccagag ccaaacctaa ccgttctttg
    13261 gactgataag ttaccatatg ctttccgtcg ctactgtatg cacatgagtc acaagcactc
    13321 ttcaatccaa tatgagggtg tgacaacaat ggctaaggac ggctacggtg aaatgtcatg
    13381 tatctcatgc tgtgtgtcac cacttgaccc agaaaatgaa gagcaacgtc ataacattca
    13441 gtacttcggt gctcgtgtga acgtgcttaa agcccttctt actggactta acggtggtta
    13501 cgatgatgtg cacaaggact acaaggtatt tgacatcgac cctgttactg atgatgtcct
    13561 tgactttgat actgttaagg ctaactttga aaaatcactt gattggttga ctgatactta
    13621 cgtagatgcg cttaatatca ttcactacat gactgacaag tacaactacg aagctgttca
    13681 aatggcattc ttaccatcac atcaacgtgc taacatggga tttggtatct gtggcttcgc
    13741 aaatactgtt gacaccctat cagctattaa atatgcgact gttaagccaa ttcgtgacga
    13801 agatggttac atctatgact acgaaacaat cggcgactac ccacgctggg gtgaggacga
    13861 tcctcgctca aacgaattag ctgagtggtt gattgaggct tacactacac gtctacgcag
    13921 ccacaagctt tataagaacg ctgaagcaac tgtgtcactg cttaccatca cttcaaacgt
    13981 tgcttactct aagcaaactg gtaactctcc ggttcaccgc ggtgtttacc tcaacgaaga
    14041 tggtacaact aacctatcac aacttgaatt cttctcacca ggtgctaacc catctaacaa
    14101 ggctaagggt ggctggctgc aaaacttgaa ctcacttgca agccttgact tctcatatgc
    14161 cgcagatggt atctcactaa caactcaagt atcacctcgc gcgcttggta agacacatga
    14221 cgaacaggtt gaaaaccttg ttactatcct tgatggttac tttgaaaatg gtggtcaaca
    14281 cgttaaccta aacgttatgg acttaaatga cgtttacgat aaaattatgg ctggtgaaga
    14341 cgttatcgtc cgtatctctg gatactgtgt caataccaaa taccttacac cagaacaaaa
    14401 aactgaatta actcaacgtg tcttccacga agtgctttca atggacgatg ccgctgaagc
    14461 tatttcagga aaataagcta atcttagcta gctaagagcc tgtctgttga caggttcttt
    14521 ttttatcaca catgcaatag gtacagctgt cctcagcagc tgaataacca gcagagctgg
    14581 ttgaaactac tagcaagcct atcattatca ttgtgaaaat cagacgatta accttttcat
    14641 taaaaaaaaa acgaaactac ggagaaaagc tgatgaggag ctctttaagg ctatcagtca
    14701 acatgttaaa ctcttcttag gaagcgttaa caataactaa ctgctaagct aagcaattat
    14761 ctattaagga gaataacaat gaaacgacta aaaacactat gcttgttagc tactgctata
    14821 accctaaccc tagctcctat cagcacaagc cagacaacaa cacagaccgt atatgctagt
    14881 gaaactcatc aaaatctttg tacgaacact ggtaacggat ggtttaaatg tcccgatgga
    14941 catggagggt ggacttggca ttttgacgaa aatcataagt caaatcagca gtcctttttg
    15001 ggaggattgt tgggctttgc tttgtctcta tggggagcta ttattagact cttttaagct
    15061 ctagcttaac taatcctcaa acaacaaaaa taagctctta gagaactaag ctctaagggc
    15121 tttttgctgt tctgataagt aaaaaccaag agacaaggac atcaaaaaca agcaggccta
    15181 tcagatatac cacctgatag gcccacttgt gctctcattc ttatctagga ctatttctgt
    15241 caaaggtcct atgaatagca tcccgaagct gtcgtctctc tttgatccac aaggccctat
    15301 catccttgtc ataggttcta ttggtgagaa aaatcgctgc ctgctgctcc tttttattga
    15361 gcatgataaa aggccctgta tagcctgtat gactaatcca atcaccctct aggctccaac
    15421 ccaaagacct gggcttttcc tgtctgctat agctttgaaa aagtctatcc gaaaagcttt
    15481 ccttcaggta atgctcaata aaccgctcta aatccctgat ggttgaaaaa agccctgctg
    15541 agcctgcatg gtttcccaag accttagcct tgggatcatg tacctctcca tcaagcaccc
    15601 ctttgaccgt tggaactgct tctggccttg ggccaaagga ggtctcagtc attccaaagg
    15661 gagtaaaaac catctcctga aaaagctcat caagagactt tccatgaagg tgctctagca
    15721 tgaagccaag caataaaaaa ttcacatctg tgtaatgaaa ggtcttatcg tccttgacct
    15781 gaagctggtg catcgctgct cttaattgct gggcattgag ctgatctcga ttgggaatat
    15841 aagggtcaag tccactagta tgggtgagta gctgtcgcag tgtaacctcc agcttttgag
    15901 cgtcaggata ataatgcctt aaaggagtat caagagccaa ggcaccacta ttgatcatgg
    15961 ctatacagac agtcgctact ccgacaacct tagagacact ggctaaatca taaaccaagc
    16021 ctttggtaac aggtctttga ccatcaaggg taccgatata atgctcctgc caaccgccac
    16081 agcgaaaaag ggctaagcta gccccatgat ataagccttc ctgaatctgc tggcttacct
    16141 tttctatgac ttctaatgtc atttgacaaa ccaaatttcg atctgacttg ggtctgaaag
    16201 aacaagcacc cttgcctttt tatctaaata aacctgacac cctttgtcct caaggtaggt
    16261 ctttagagca agcaagtcat agctatctga cacctgaaat tctaaaatct ccaaatccca
    16321 tgtgacatgc gggacaatcg tcaaatcttg accagcctcc ctattaaact caagcgtgac
    16381 cggcaggcaa tcaccaaaaa tagactgata aaaagctctg gattgctcgt catctaaaac
    16441 atttaagaca atcagatcaa agctaaactg actcagcccc ctaaagtcag cttccttgtc
    16501 aattgcagga acatcatcga caatgtcaag ctccttgata tcgtcctctg catggagtaa
    16561 gaagcgatct ccctctggtg aggtgacttc aaaggcatag cctttttttc ccttgaaaat
    16621 caaatcatag tcaacgccat gagctaggag ctgctcaatg tccttaggag cagttgtttt
    16681 gataacaatt gtatttactt tcttagggcc atctacaacg cgtgttcttg ctgctggaga
    16741 ttcttcaatt acaaagcgtt cttgtccttg gccccaagat gaaaaaattg atatcgcgtt
    16801 ttcctctgac actagcctta agcctagatt tttttggtaa aaggcaatat taaggtcgcg
    16861 attgttaaca cgtaatactg gggttttaaa gacaatattg tcaaataaag tcatatattc
    16921 ctcctaatcc tctgctatta tagacaaaat tccaattttt gacaagaaat tatatgcttt
    16981 ttaaccgcct gtcacgcgct accaaggcaa tatagcactc acagccatca ccagacttac
    17041 taggtccaat cttccttcgt gcgctctatc acaagcagct ttccttagcg taactcatgc
    17101 acatattggt aaatgcgact ttttcaaaat agcacatgaa gtaccccttt aatttgactt
    17161 ttccttaacc aaaagcgaga acctttttta gttctcacag tagcaatcac actcttgaaa
    17221 tgtgatttcg ctctcctcaa taacagatga taactgaaat tgcccggatt ttcttatcca
    17281 cgcgcaactt caaaagcacc ttatcttcag cattagtaag gatactacca gcttagctca
    17341 gaccagattc agctggctct tgctggcaag cttttatcac aaaaaagaag gcctaagcct
    17401 tcttttttac ttgatataaa ggaatttgaa tgctgctact gctgctactg ctgctagcac
    17461 tggggcagca accggtaccc atgagtacca ccattttgaa tcccccttgg cttgtccaag
    17521 gactgatttt ggtaagaaat ggtgaaccaa acgagggcct aagtcacgcg ctgggttgag
    17581 cgctggacca gtaggaccac caagagaggt cacaagagtc atcaccaaga aaccaatccc
    17641 caagtgagct actgcaagtg agcctgtcac gtaaggagag atttgcgttg cagctgttgt
    17701 ttggtcatag ccagcctcta ccagcttacc aacaagctcc acaccaaagt aattcttggt
    17761 taaggccatt gcgccaaaaa agaggacaaa ggaaccaaca aactcgttca aaaagccatt
    17821 aatgtaggct gccttacggc tgcccttgtc accatcatca actgctgaaa tcgttgagaa
    17881 ggatcccaaa atattgttag ggttgtctgt ctgcacaaaa taaggcttgt acaccgcaac
    17941 aaccactaat tggccaaaca tagcccctag caattgagca agaacatatt gtaaaacgtg
    18001 tgcccaaggg aacaagcctg aaactgccaa gccaaaggta aaagctgggt taatgtgatt
    18061 tccagaaacg ttaccaaaca taagtgccgg catcatcaca ccgaggccat agccaaaggc
    18121 aatcacaagc cagcctgagc ggttaccctt tgttcccttt aagtcaacat tggcaactgc
    18181 tccatttccc aaaataatca aaaatgcagt ggcaataaac tctgtgatgt atttcacagt
    18241 ccatgttatt tccatattct ctagtttcct ccaaatgata agtataacag ataccatttt
    18301 atcagggata ctagttcttg taaagcctat tgtaagatat tgcctgctta atatgtttac
    18361 agtgtttttt cacaattacg gacaactaat aagtcttttt tagcatgtcg caggatatac
    18421 tctgaggtcg atccaatcag cagacgctca aaggtattta agccagttgc tcctaccatg
    18481 atcaaatcag cctgctcctt ttcaggtatg tcactagcta agagcttttt agggttgcct
    18541 ctttcgatga tttttttaat gctgctaacg cctctgcctc tagccatttt ctcgtaatag
    18601 cgcaacacct ccttggcatg ctcctcttgt gtgtcaaaga cataatcact aaccattgca
    18661 tcaccctgat aggccttaac atcaataaca tgagccagca gtaagaccgc atcattgcga
    18721 agggcaacat taatggcctt ctcaacagct aattctgatt cgtaagagcc gtccaccgca
    18781 gccagaatcc gtttatattt gcttatcatc tttgtctcct ttcgttgatt agcctttatc
    18841 aatagccttt gcttgtgtct ttaggaaata catgactgcg caggcagctg gaatgagccc
    18901 tgccagccag aacaattgat gaaaggactg cacaccagac ccaagaagca tatccttgat
    18961 gagtcccaac agataaggtc ccgcacccaa gcccaaatct agcccaatca tataagtaga
    19021 catagcggta ttaaagcgat gctcctcaac ccccttgatg gaggctgcct gtccgcagga
    19081 cataaaggtt ccatagccaa agcctatcaa agcacccgaa agcagatagg gaaggctgct
    19141 tgtcacacta ccaagcagga aaagccctag cgccaaaaag agatagctgg gataaagaac
    19201 ccactgctcc cccttaacgt ccatcaagcg tcccatagca ggtcgtgtga tcgtaatgat
    19261 caaggcatat accacaaaga aataggctcc caccgtcgtc aaatgaatgt ctgttgtgta
    19321 taatttttga aagcctagca cagaagcata ggcaatcccc atcaaaaagg caatcaaggt
    19381 gataaataag gcctttcgct caataaagct atcaactgtc caggattttg tttttgccag
    19441 ctgctctgag ttgagggcaa tatctgtcac aggaaaggca aaggccccta gcacaactac
    19501 tgcgatcaac acactgcaca aaataataat catccgaaaa tcaatgtgca aattatccag
    19561 cataaaggtc ccaacaaaag gaccaatcgc cgccgctagg cttgttgata gaccataaaa
    19621 attaatcccc tctccgcgct tgctagctgg aatataggca gtcacaatgg tattggttgc
    19681 tgttgagaca acaccatagc caaagccatt aaacaagcgc acaaaataca tcatgccaat
    19741 cgttggcatg aaaaagtagg ctagcgttgt taggagataa aaaatggcgc ctcctcttag
    19801 cactaagcgt cggccaaaaa cctccaattg cttgccaaaa atcagtcgag ccagcagggt
    19861 tcctaggata taaatccccg tcgccagacc tgcctcactg gtcttagctc ctaattcctt
    19921 agtcgcaaca aaggcaatga tcaccgtaaa caagtaatag accatataca caataaaatt
    19981 taatactgtg atccctataa aatgcttgtt aaataatttg tcttccactg aaaatgagct
    20041 cctccctatt tcattaacat tttacaaaaa aatcagataa tgccccattt caatggtata
    20101 atataggtga tactattaaa cgacattagc aaatgctaag cattgctgca gcaacaaatt
    20161 atataatgat accagaaaca cctctaggag aaaagcgtga accatcaaat cttacagcgt
    20221 tatattgaca gtcataactt tcctattatc gaaaagggct accacaaata cctgaccttt
    20281 gaaagcttag aggaggattt tacgtatatc ctaaaggagg gcattgtcaa gcaaagcgtt
    20341 ctgtcaaaat atggcatgga atttaacctc aggtacgtca caggccttga gatcacctct
    20401 gtgcttaata ctggctattc caaggacatg agagagccct acaatgttcg catcgaatct
    20461 gagactgcca gcttttataa ggttcgtcat tccacctttt taagggatat tagcgaggat
    20521 atcgagctgc agggctatgt caaggacttt tatcactacc gcctccaaaa atcaatgaaa
    20581 aaaatgcagt gtatgctgac aaatggccgt atcggcgcta tctctactca gatttacgat
    20641 ttaatgaccc tttttggacg ccccttggct aatggccata tccttattga ttttatcatc
    20701 acaaatgagg agctgggcaa attctgtggc atttcgactg ccagcagtgt cagtcgtctc
    20761 ctaaagcagc tcaaaaaaga gggcattatt caaatcaatg accagcatat catcattacc
    20821 aatttagaga agctaaagga taatattgtt ttttaacgat ttagaaagga cgtcccatgc
    20881 gctataatca attgtcttac attcccacca gtctagaaac agctgtagct gagcttcagg
    20941 ccctgggctt tgctgtccag caagagcaag cacccaagga gaacttcgct attttcctta
    21001 gaaagctatt ttttcatttt caggataccg attatccctt gaaccatatg attgcaagca
    21061 aggatctcga cctattgacc tttttaacat ctgatgcaac actgacaaaa gaggtttttg
    21121 atttagtggc cttacaggtc cttggcttta ttcctgctgt tgactttacc gatgcacagg
    21181 actttataca aaagattggc tttccgattg tttttgacag ccagcaatta ctactcaatt
    21241 tacatcagct gcttgcaacc cggcagaagt ccggtgtgac cttgattgat agccttgtta
    21301 gtcagggctt gcttcctatg gataattgct accactactt caacggaaaa gccctagcaa
    21361 cctttgatac caccagcctc attcgcgagg tggtctatgt cgaagcgcca cttgataccg
    21421 atcaagacgg acagcttgac ctcatcaagg tcaacattat ccgccccaag gccagcactg
    21481 ctatcccaag catgatgaca gccagccctt atcaccaagg gattaacgag accgccaacg
    21541 ataaaaagct ccatcgcatg gaaggtgagc ttagccctaa ggctcctcgt aggattaccg
    21601 ttgagccaac tgattttcag ccgcttgcca ccaagccctc aaggcttcct gtcaatgagt
    21661 gccaagagac cttcagccat atcagctcct acacactaaa tgattatttt ctagcgcgtg
    21721 gctttgccaa tctctatgtc tcaggagtgg gaacagcagg ctcaactggc tttatgacaa
    21781 gtggtgacta cgcccagatc gaaagcttta aggctgttat cgattggcta aatggcagag
    21841 ctactgctta cacgagccac aagcgtgact atcaaatcaa ggctgattgg tcaaatggct
    21901 tagtcgcaac aactggaaaa tcctatcttg gtaccatgtc aacaggactg gctacaacag
    21961 gtgttgatgg cttagcagtc atcattgctg aagctgccat ttcttcttgg tacgattatt
    22021 atcgtgaaaa tgggctggta tgcagtcctg gtggctaccc aggagaggat ctcgatgtgc
    22081 tgacagagct cacctactcg cgtaacctgc tgccaggtga ttacttacgt cacaacgacc
    22141 attatcaaca gctgctgagc caacaatctc aagctctcga gcgccaatca ggcaactaca
    22201 atcaattttg gcatgaccgc aactacctgc cacaggctga tcgcatcaag tgtgaggtcg
    22261 tctacacgca tggcctacag gactggaatg tgaagcctag acaggtctac aatatcttca
    22321 atgccctgcc tgatagcctt ggaaagcacc ttttcctaca tcatggtgag catgtctaca
    22381 tgcacaactg gcagtcaatt gattttcgtg aggccatgaa tgccctgctc tgtcaaaaaa
    22441 tgctaggaca aaataatggc tttaccctac caacaatcat ctggcaggat aaccaaaaag
    22501 aacaaacctg gaaagagcta acagcctttg gcggtcacag caagcgtcag attgccctag
    22561 gcgatgatca tgtcttaatt gacaatcact atggcgaaga ggactttaag cgctatagca
    22621 aggattttcg tgcctttaaa gctgagcttt ttgaaggcaa ggcaaatcaa gcagtcattg
    22681 atattctgtt agaagaggat ctaccaatca acgggcaagc ctgccttaag cttaagctaa
    22741 aatcaagtga aaacaagggg attttggctg cacagctcct agattatggc aagaaaaaac
    22801 gctttgctga tatacctgct attcttgagc tagacagcat tgacaacggg cagcagtttg
    22861 cacgtgaagc gctcaaggag cttcccttca aggacagccc ataccgcgtt gtcaccaagg
    22921 gtgtcctaaa cctacagcac cgcagcgacc tattgaccat tgaggatatt ccaaatgacc
    22981 aatggatgac catcaccttc cacttgcagc caaccatcta tcatatggcc aagggagaca
    23041 ccctaagagt cgttctttac acgactgatt ttgagcatac aatccgcgac aatagcaact
    23101 atgccctaac cctagatttg gagcaatcct atctcctaat ccctactgat gaggaggaat
    23161 aaatcaaagc gcatcaaaaa agcctgagat cacaatgagc tgcaccccaa tcgttagatc
    23221 ctttgtctaa ctgttggagt acagctcaaa gctctaggct tttttaacta ttttgaaacc
    23281 tttttaccag cctcagcacc agaatgcagg ctgtagacgg actcgatatg aatcaagcct
    23341 gctgcctttg gtgcgcccat cttgccttct gcccattcct tggcagcctc aaagacagga
    23401 ccctctgtaa tgatttccgc acgccctaca aagcgataac cacgcaattg ctcgcgattg
    23461 acataagcga cctcaatttt accattagcc tgaatattag agcaggtttg gccgccagta
    23521 ttttcattat aaaccaaggt ttcatcgtct aacagtctca tcgaacgctt agggccaata
    23581 ttaggattac cctcattatc tacagttact accattgcta attgctcagc aatcatttct
    23641 ttcatttctt ctgttaacat ataatctcct cttaatcgtt tctatagtca gctgactacg
    23701 ctttgattat agcacagtta agcagaaaag ccgacaaaaa taggttagct taaaaaagtt
    23761 ttacagttta cttaagatta gaatgattct cgctatctag ccatcaccct tgatcacagt
    23821 aaaaaggcga ttagcaagca agcactcttt atttcataaa atccgaatcg tcgcccaaaa
    23881 aaaatatcat caactgatat ggtcaatgcc tctgcaatac ctcttaattt ttcatactta
    23941 gctcgcctaa gcttttgcac atccttttca tatctggcta gtgtcctaac agaaatccca
    24001 gttaacgctg acagttcctt ttgggtcttt ttttgagcaa tcctcaattc ctttaacgtt
    24061 gcttttgaca atattttccc tccgcctctc atctcaggta atattaatga cagatgacaa
    24121 gtttattata gacttcggtt tttatgaagt caagtctttt atcgcacttt ccccacttct
    24181 ttttctaaat cttttgattt agcttgattt gtggtatcat atcctatata gaaataaagg
    24241 agaatggaaa tgtccgaaaa gaaaacattt tttgcaacta atttaaaata tcttcggcta
    24301 aaaaagaata tggaacaatt agaacttgct aaccttttag gacgaaaaag ctcttcctca
    24361 atcagcgaat gagaaagagg aaagtacact ccaaaatctg gtctcctgag tgacattgct
    24421 gccatctttg atgtcagcct gacagacctc atggaaaagg atttaacact ggaaaataag
    24481 ggagtgactt atcagcttcc ccaaagagat ttagtaatga tttcagagca gctatctgaa
    24541 aacaattata acaaatggct ggattttggt caggatctct tatctcatca ggataaagaa
    24601 gaaaatcaca agccaagcaa ataaagagcc tcacacgtct tattctcatc aagtttcgaa
    24661 aaatcaccta ccactcaagc acacaaaaag ccttggcagg gcttctaagc ataagaaagc
    24721 tgtatcatat caatacctca gggaccatga tatgatacag ctttttgtat ctcactttta
    24781 gacaaggtag ccacataaag cttgcagatg acctacctct gtattagcta ccacaaccaa
    24841 cagctagcta gactggcagg ccctctataa gcctcagcgg attatctaag cactcccaac
    24901 agctccaaca aaataaagac ataaccaata ccattattta agatatgggc tactgttgaa
    24961 aaatagatat tcttcttcca aacataaact aagccgagca aaagtcccag tccaccatac
    25021 acaacgatgg aagatagctc gctgaaggaa tagatatgaa ccaagccaaa tagcaatgat
    25081 gatcccaaca atcgagccag cagcatacct gtgcctgatt ggccctcacc gattaaaatc
    25141 ttgcggaaaa taagctcctc attgaaggga ccaataatac tcaccaccag aataaagatc
    25201 actgtctcga agccctcact agcattatag cgattagcta aaacagctgc attgctgctc
    25261 tcttctaaag gaaggctact gagcaaaata tttgcaacat aaagcactgc aaaaatgacc
    25321 aagacccaca aggtattttt gacccatttt gttgaaaact gccgccagtc cctctgataa
    25381 tctgctcgat aaagccaaca gatcccaagt gcaaaaatca gcagatgtct cccgtaaaat
    25441 aaaaaggtat tcaataaagg cggaagctca atcacattgc taacttgtct ataaagatac
    25501 acagcaatga tatatagcat gaccagtaca gctgcacgat gacgtttgat ggtatccaat
    25561 tactcttcct caattctaat aattgtcaga ttagctaggc tatattgcca tcagctaatc
    25621 ttgatcttaa atgtgactaa tttacaagca ctcaactttt gaatcggtaa agctgacaga
    25681 cagccctacc ctagcttcaa taaagctatc ttccaatagt ccttgcgctc atcagaactg
    25741 tcaaaggcct gacccagctg agtcaacaga cttatccagt caacatcaca cagaacaaga
    25801 ccatcttacc atatccctgc caactataaa agcccctaac ctgacctatt tgactactaa
    25861 cagcaaaaaa gcagcttaaa aacaccaatc agacgccacc aaggactctt gatcagcgca
    25921 gctcgcacag acacctgaaa aatgacagac aagcctctta aaagcacctc agcaagctga
    25981 gccaaccctt cacagaatag acaaacaaca agagctaagt caagacctca agctagcaga
    26041 ttacaggcag agacgcttgc aaggcttacc cagcaaaaag caacagactg ataaaggatt
    26101 cacaccacac agccacaagt caagcagcta gcccaaacaa agcactgctc accaaatcct
    26161 actatgcttt ctggtagccc ttatccattc aaaatcgtat ccaaggcttc ttgatattgc
    26221 ttgtctcgca attctctgat cacctgtgat aaatactctg cctgatacat cacaaagtca
    26281 aaattgaaat ccagaatttt ggtgttctca ttcaatgaca gcctctcctc gataaaagca
    26341 gtcatctcag ctgttgtcac aatcaagtca aaatcagttc tccaaggcaa ttcagcctct
    26401 gacaaaatat taaaacgata gacctttgca acacaaggac tcacctgttg catgaccaag
    26461 ctatataaaa tatcaatgtt tttcttgttg atttcgatca ctgctatggc taaaggtggc
    26521 agaccttctc taacaagctg ttccagtcgc gtgcaaagca aatgcaaatt agagcctgtc
    26581 agccgaccaa caccagaaac ccgctctgcc cagctattaa tcatcagctc gatacgattg
    26641 gccaagagct tactgccttg atattcctcc gcataataat atttttgcgg gataaagagc
    26701 gacaaatcaa acaaggtctt acgaaaataa ggaatcaagg tctgaataca agccttgtca
    26761 aaggcgatat agtggccaaa caattgacgc agctcaccca gcagctcttg gtaagcagga
    26821 tcctcctgaa tgatcgtcaa taaggccgaa gaatcctcct cagaccattg tgtgatcgaa
    26881 aaagagttgt taaccgtcaa ataaacgaga aaaatataat caatctcgct actgggaaag
    26941 tccatatcaa gcaacaattt cccctcacgc ttgaaaaagt cctccaaata cccataaagc
    27001 gccaaagact ttaagcgttt aaaaatcccc tcctgaggaa tcgcaacgtc aaactctcca
    27061 cgcttccaag atagcgacaa gagcacatca aaaaagcgaa acttcttatc cagtaacggg
    27121 tgaggcgttt gttgcttttt gatcgaaaag ataaagtcat gcacaatatc cagatcatgg
    27181 tcagtcagct catagatgac aatcccgtac ttatcatgca ataaagcaat caaatagcgg
    27241 atacgccact cctcaccaac aacactatta tcctctaagg ccaagccgca ctcctcaaca
    27301 aagggcttca tgtgctgaat cagccgataa gctgacggtg tggaaataaa atgctcccta
    27361 gcaaagcctg agacagattt gaccttatag caaggtgcct tgatcaagag aaatttaaga
    27421 atgtgcagcc gtaccgattg gcggtaaatc gtcttcaaaa acggtttgcc ccttttcaaa
    27481 acggtgcagc ggacaatggt gctatcccac tcaaaggcga tatctccttg gaaaagctcc
    27541 tctaattggt ggatatagcg ctttatgtta gctaggctaa agcccgtctt ttgctgaatg
    27601 gcgtggaaac tgatcctttt tttaccaagt agtatggtca gcagcaaagc ctgatgatta
    27661 atcactggtt ccaaatactc ttcaagcaaa acactttctc ctccttaaac catttcgtta
    27721 gcgtcattat cataacaatt tttaccaaaa aagtgatgaa aaatatttaa tatcaggacg
    27781 atttttctga tagcctttat tataacacaa aagctcaagg caggtaaaac gataaagaaa
    27841 tcaacttaaa actatgacac agtctcatct catatgatat agttattcag gtttcctaat
    27901 ggaaaacata ttaacaactt aataatggag agaagaaagt tgaaaacaaa atcatttaga
    27961 aaggtactga caacgtcagc tacctgtatt gtgctggcaa caagctttgc cggaggaacc
    28021 ctaagagtct gggcagagca gctttattat gggtggaatg atggaacgag acaaagttcg
    28081 ccatattttt tgtacgtatc gcctaaaaat gctccaaagc gtgaattaaa agacgagtat
    28141 gttgtttatt gctttaacaa aaaattgtat tggccagatc aatgggaatc tatatacagc
    28201 aattttaatg acatcagatc tccatataac gatttacctg tatatgagaa aaaactagga
    28261 tatgatggta tatttaaaca atatgctcca gattacaaaa aagatattag tgatatcgca
    28321 agtgctttgg tggcagtttt aagtaatgga taccccacta acaagtcaca actatcaact
    28381 agctaccatt taaataatga ttcttctaga aaagttactc aattagccat ttggtatttt
    28441 agtgatagtt taacaaaaga ataccttaaa gatacgggtg gttataactt aaacgatatg
    28501 gaaaaaaaag ctttagattt tttaatcagt aaaggagagg attctaagct taaatcagag
    28561 cagagtaatt actcattgga tatttatgtt tatcaaagtg gcgggcatga ccatatgaaa
    28621 gattaccaaa atcttctcgg ctctacctta attcctaaag aaccgctaaa gcctcagcta
    28681 ggtggtttta gtggacataa tggaaatgga ttaagcggcc ttgaaggagg atcatcaggt
    28741 tcacaagaaa ctaatgaaga tggtaagaaa ggacttatag gtttccatgg aggactctca
    28801 ggaagcgagg gcaaacgaga tcctttccag gattgaaggg tgaggctggt gcacctgata
    28861 cacctcaaaa gcctaatgac ccattgcaaa gtcttgaagg tggtaactct cctatcgtag
    28921 aacaaaacta tggtagtact gagggatatc atggtcaatc tggcattctt gaggaaaccg
    28981 aagacactaa cccacctggt atcattttag gtggctcagg aaatgtcgaa acgagatcct
    29041 catctgatgg ggcttggcgg tggtctagct ggcgaatcag gagaaacgac acctaaacca
    29101 ggacagactg gtggtcatgg accaatcatc gagacaacag aggacacaca aaaaggcatg
    29161 tctgggcaat ctggaggcac tatcgagtca gaaaacacca aaaagcctga ggtcatgatt
    29221 ggtgggcagg gacaaaccat cgaaacaaca gaggacacac aaaaaggcat gtctgggcaa
    29281 tctggcggta ctatcgagtc agaagacact aaaaaacctg aggtcatgat tggtgggcag
    29341 ggacaaacca tcgaaacaac agaggacaca caaaaaggca tgtctgggca atctggcggt
    29401 actatcgagt cagaagacac taaaaaacct gaggtcatga ttggcggtca gggacaaatc
    29461 atcgacttct ctgaaaacac gcaatcaggt atgtctggac agtctggaga cactacggtc
    29521 attgaggata ccaagaagtc tgagataatc attggtgggc aaggacaaat catcgacttc
    29581 tctgaggata ctcagccggg tatgtctggg caatctggag gcaccacaat tgtcgaagac
    29641 accaagaagc cgacacctaa gcctaaacct gcacctgcgc caattgttaa tgacgaaaaa
    29701 cctaacaaag gcactcagct cccacagaca aatgatatga agcaactcac cctaagcatc
    29761 atcggtgcaa tgtcaatgct gcttgtccta tgtctgtctc tattcaagcg accatctaaa
    29821 aaagactaag caacactgac aagtgatcat tattgtacgg acgtttacag gcgggctttc
    29881 tgccctctta aaacaccgta caacaacaaa acggtctaaa tagaaatatc cctcaagggt
    29941 tagacaatcg ctctagccct tggggctttt tttgatactt ataatagaag agagcaagca
    30001 gtgacacttt ctttttgccc tatatctgct aacactagcg gtatgtgcag ttaccatagg
    30061 ctatcaactc gtcgtgcaac tctagagaaa agctgataca aaaaacaagc accagccttg
    30121 ctgctgatgc ttgctccgga cttactgata agcctttgtg atgtcctagc tttataacca
    30181 tatgcctatt acctaaaggt ctagtctcct aatggtgggc tggctggtaa aagcaaggag
    30241 aaacagctcc cctttccaag ctggctctca acagcaatat ccccacctag ttggcgagct
    30301 aactgcctag caatagagag ccccagccca tgaccaccag tcttcatatt gcgagaggcc
    30361 tcaacacgat acaggcgctt gaaaatcaaa ggcaggtcct cttttttgat cccttgcccc
    30421 tgatcaataa catcaatgcg aatggactgc tcctgttgat aagcatgaat cgtcaaagcc
    30481 gtattagcct ttgaatattt aagcgcattg ctgactaaat tcagcataat ccgagacaaa
    30541 gcatcatatc ggctgctgat cttaaccacc tcttttgcca cctcaatatg aacggagcgt
    30601 ttttcctgct ctaaggtcaa ttgaaattcg gatagcatgt caatcaatag cttttcaaga
    30661 tagatgattt gaagctgctg cttgtcgtct tgcttttgat catttaagct gaccatatgc
    30721 aattcttcaa ctaattgatt caaacggttg gtctgtcgtg agatggtgtt tagatagtgc
    30781 ctttcctctt cccttggaat aacgccatct aaaatcccct ctacagttgc ttgaatagag
    30841 gtcaagggtg tcttaatatc gtgcgacagc tgagcaatca tcatggattt ctcatgctca
    30901 ctctcactca atgactcaaa gctgaccttt agctctgagg acatctgatt aaaggcttcc
    30961 tctagatctt taaactccaa aggacacttg atgagctgac cactatcaaa gtttctttca
    31021 gaaatagcct gtatcttttt ctttagcctt ttaagcgatg aaaaaacatt actcaaaagg
    31081 atcatattca caattcctcc ggctactgaa gcaattagag ctattactaa aatatatgaa
    31141 atatcctcaa tggtaatgag catttggttt aacccaacaa tcaggcctgc aatagtaatc
    31201 agcatagaca ttaaatagcc aatgacaatg tacgttctta atcgcatgct acccctctaa
    31261 tttataacct agtccccaaa ccgttttaat ggttggtgtt tgctcggtac tgtattttgc
    31321 caagtcattg cgtagggaat gaatgtgaac atttaaggta ttggtatcat ctaaatactc
    31381 ctcctccca
//
LOCUS       DARYYD010000025        30591 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.025, whole genome shotgun sequence.
ACCESSION   DARYYD010000025 DARYYD010000000
VERSION     DARYYD010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30591
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.025"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(109..792)
                     /locus_tag="TV188_001024"
     CDS             complement(109..792)
                     /locus_tag="TV188_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEL1534390.1"
                     /translation="MLLDVVIQFRDRRSTITIDTPSTCPHCGRTMSPQHVGESKSSDN
                     ESYSYQGHFSVIFRCSFDDCLKYFAVEYIHDQIGKGSAVAYFYRPPIRVNLPENVDKV
                     SPAFVEIYSQATIAEQEKLDQIAGVGYRKAAEFLIKDYTISKNPDDSDNIKQIMLGKV
                     ISDYLSDFPKLQALSRSVAWIGNDETHYVRRHNNKDLQDLKRFILAAAQFVAADYDAD
                     DALSFTSTD"
     gene            850..1038
                     /locus_tag="TV188_001025"
     CDS             850..1038
                     /locus_tag="TV188_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534391.1"
                     /translation="MEETASVNVTVKINNITEFSTLVEKFNEKARELEAISHELMRFK
                     FQGEIESRALSDNANEIE"
     gene            complement(1012..1479)
                     /locus_tag="TV188_001026"
     CDS             complement(1012..1479)
                     /locus_tag="TV188_001026"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534392.1"
                     /translation="MDLNQVRLLEACHRYLVDRVHIDIKENMLNDKLVFEFNGDFVTF
                     NTYQEVGHCCFYEYELGSYEELENHRSIDVTEILSILNLKSGQIGTLSMLTDITRVRA
                     YIFKLLSQADFAKFEKEIKNTNFAYNFRYVENYSYLPCVKIDKDKLFNFVSII"
     gene            1553..1741
                     /locus_tag="TV188_001027"
     CDS             1553..1741
                     /locus_tag="TV188_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1534393.1"
                     /translation="MQILLYKLRKEKRISQEEMSKVINKSSNTYRDKELGKRDFTQSE
                     MFKIANFFHKELGEIFTP"
     gene            1792..2508
                     /locus_tag="TV188_001028"
     CDS             1792..2508
                     /locus_tag="TV188_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEL1534394.1"
                     /translation="MNQLINITLNENQEPVVSGRDLHKVLEIKTAYKDWFPRMAEYGF
                     EEGQDFSSFLSKSTGGRPSQDHVLKLDMAKEIAMLQRNEKSKQVRKYFIQIEKDFNSP
                     EKIMARALLMADKKVHKLEAQIEADRPKVLFADAVSASKSSCLIGELAKILKQNGINI
                     GQNKLFQWLRTNGYLISRRGESWNQPTQKSMQLGLFELKKTAINHSDGHTTTNVTPKV
                     TGKGQQYFINKFLNQEYLPV"
     gene            complement(2663..2878)
                     /locus_tag="TV188_001029"
     CDS             complement(2663..2878)
                     /locus_tag="TV188_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018379530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534395.1"
                     /translation="MVDKYIPGRYIQREIDEIIELVRDRSKFEPVRVREVQEHIQKIL
                     IQHEAEILARLEENQDQKASENSNDIF"
     gene            3067..3357
                     /locus_tag="TV188_001030"
     CDS             3067..3357
                     /locus_tag="TV188_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534396.1"
                     /translation="MAIEVFGPDFRKELLADLISLNREALKIAQFENSKSIEWVTMKR
                     LEKETGWGRTKLTQWREQGKFNFKRSSENGKVLYDLADVNRFLRTSGYEKGA"
     gene            3359..3553
                     /locus_tag="TV188_001031"
     CDS             3359..3553
                     /locus_tag="TV188_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534397.1"
                     /translation="MNKLELFLLAATVILAIIARIQYEVIKKHNSPENKRKIFREVAL
                     ENSKRWSEKRSRGEVEKCLL"
     gene            3688..3867
                     /locus_tag="TV188_001032"
     CDS             3688..3867
                     /locus_tag="TV188_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534398.1"
                     /translation="MTTTKKLGRPTSNPKSHSKRLRMTDEEVQKLEYCTKQTGKTQTD
                     VLMLGLDKVYQELKK"
     gene            4040..4312
                     /locus_tag="TV188_001033"
     CDS             4040..4312
                     /locus_tag="TV188_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534399.1"
                     /translation="MDNSKLANHQKVTVVCTDFNVYLNGIRLTGARPETAKLAERCGE
                     KLITLSLVVTDFDDHRTPKMADMAKEAEMANKTLDWEKKHFYKSNK"
     gene            complement(4302..4682)
                     /locus_tag="TV188_001034"
     CDS             complement(4302..4682)
                     /locus_tag="TV188_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534400.1"
                     /translation="MIDYYSLYKNSLEAIGYHKLDTGVDLLQYLIATEEGKRIYSQYP
                     YREVEEIIFYTLDCLIQQDLVTATEMPRLDRRIYTIDGLTPKGMYFLGYIGQVETEVI
                     EWLNEFGVSQNPESIYNALRYIIY"
     gene            4738..5181
                     /locus_tag="TV188_001035"
     CDS             4738..5181
                     /locus_tag="TV188_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534401.1"
                     /translation="MAKTYTLTEEELNELVAERMKQAKEKRTPQGLFKDVSFDDELIP
                     INEKYPKVLKKLNRERAYKPEKHVFNQTPKVFGVDNDISYSKITTHDVHNHIRLLVLN
                     VFGKSQNKEVLPEEYDQAIELYKELKEWFVSSYDKRLEGLVLEDD"
     gene            5298..6110
                     /locus_tag="TV188_001036"
     CDS             5298..6110
                     /locus_tag="TV188_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017285243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1534402.1"
                     /translation="MGKEKTKIYFWLKFDKKFFENIFIKRLKKMAGGDTMTVLYIRLM
                     LESLETDCILYYEGYFENLVEELAIKLEVSEDDINMTLAYFTKCGLIQIDGSGNAQMP
                     QAKAMLESETNWAKYKRETRKIGQIPTNVQPMSNQCPTEIEIEKDKKKDINIDIKSEV
                     EEEIKEISTADENSLKIISDYFQQEIGILSPNQFEQLSDYITITKMEVDVVKSAITRA
                     ADNSKRSFGYVNSILRNWRQNGITTMVKVKEESRNFKARKAKQEEVSEYDTW"
     gene            6097..6879
                     /locus_tag="TV188_001037"
     CDS             6097..6879
                     /locus_tag="TV188_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1534403.1"
                     /translation="MTLGDNNALAKIAVAYQKNVKKESTVCQKHGCIYITILKTGLTV
                     CPMCHKEDLESQNELHVQKQYERELENKRLYYLKKLSIMDDELENASFDNFRVITPKQ
                     QEVLSWAKSMANYWYTGGKGNIIMTGKAGRGKSHLAYSIIRGLSDETKKLGLLVNITD
                     LLSEIKRDFSQEAFWLDKLKNVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTN
                     LTPVEIRKNYGERIASRIRKGCAKSHIMDFAGLEDERIKLWN"
     gene            7016..7222
                     /locus_tag="TV188_001038"
     CDS             7016..7222
                     /locus_tag="TV188_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534404.1"
                     /translation="MTPEEAEKAKIRAKQEIEVFSIYLEQAIDTFGSMLSPQEVFLAA
                     GFAYLGAGQTDIHAAVEGLYEQVR"
     gene            7384..8310
                     /locus_tag="TV188_001039"
     CDS             7384..8310
                     /locus_tag="TV188_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HEL1534405.1"
                     /translation="MANQLSTYTHKQFFNAPTIQKAFDDVWKGAGTQFAVSILSVLQG
                     SKSLKSASNESIYAAAMKAAVLNLPIEPSLGRAYLVPYKGQAQFQLGYKGLIELAQRS
                     GQYKNINAGIVYKSQLISYNPLFEELILDFSKPQDEIVGYFAAFKLLNGFEKVSFWTV
                     EKVTAHGKKFSKSFASGPWKTDFDAMAQKTILKDILSKYGPLSVEMQKAIDEDNQDST
                     ISIPKDITPPETNSLDDLIGHQNEKKDAPGNLKDVTDDLHSEPEKTLTDENKTVLEDT
                     SYPADEIPDFDQETGEIKASEGNLFDNLGDLI"
     gene            8307..8507
                     /locus_tag="TV188_001040"
     CDS             8307..8507
                     /locus_tag="TV188_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534406.1"
                     /translation="MIKLVKIEGYYINPEYVVGVWERSALNFDDLDEKVVVIQFVGDR
                     EREECVFYDTPIDEVIKRLLDD"
     gene            8500..9297
                     /locus_tag="TV188_001041"
     CDS             8500..9297
                     /locus_tag="TV188_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HEL1534407.1"
                     /translation="MTSLDLLGKDYYSKESAIRYWSISQYKRFRECEARALAELRGDW
                     TDTRDNTALLVGNYVHSYFEGEEAHEEFKVQNSSEMISTRGTTKGQLKKDYLVAEQMI
                     DALKSDNNFMAIYQGEKEVAITGFLGEVEFKGKIDCLNAERGYFVDIKTTKGPIDDKI
                     WNGQERVYWFEAYSYILQMAAYKNMLEAKHKKPFEPIIYAVTKETPPDTRAIRIQNLD
                     AMQNELDNLAQNIKRLDDVKKGIEKSKPCGHCEYCRANQLTQRVMIF"
     gene            9476..9817
                     /locus_tag="TV188_001042"
     CDS             9476..9817
                     /locus_tag="TV188_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534408.1"
                     /translation="MEQIKITGTGTALILDRVNRIFAISGGLTMQWDFISDFKKIDDE
                     PSLDEDGELFEVAYDLVLEAKPKTKINLTSSYFAKEHKKDTDEIIKVFSFIEDNKRNI
                     FETLGIRGVLE"
     gene            9814..10326
                     /locus_tag="TV188_001043"
     CDS             9814..10326
                     /locus_tag="TV188_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534409.1"
                     /translation="MSNLVLSLDISTSGTGWALFKGSDLIQSGVLKHKSDSYFERGRY
                     MASQLRAIQSRALKKYDCSFSTIAVEKNSVMGPNQQSMLKIGIVTGIILGRLIADNVV
                     FINVSTWRKHWKFSYKDRSKKAMKAQSKAKAAENFGKIVKDDEADAVLIGAYYVNQGY
                     LDGLETHDYY"
     gene            10313..10525
                     /locus_tag="TV188_001044"
     CDS             10313..10525
                     /locus_tag="TV188_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534410.1"
                     /translation="MTTTKKHVVRIYNKGITATYAVTDKRLFREHEFATKREAMQFIR
                     ELELANDKRATEYYLREWRDANGRYV"
     gene            10503..10787
                     /locus_tag="TV188_001045"
     CDS             10503..10787
                     /locus_tag="TV188_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HEL1534411.1"
                     /translation="MLMEDTFKKIKELEAACQDRTDNIKKPSHYQGRHGMEAIDVVKN
                     FAACPEHEEGFYWGNAVKYLLRYHAKNGVEDLKKARQNLDWLIEKLEEVE"
     gene            10812..11024
                     /locus_tag="TV188_001046"
     CDS             10812..11024
                     /locus_tag="TV188_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000010060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534412.1"
                     /translation="MSFRLSWEINGQTVEVIGDYKTLKAAYDSIKVHVKDRDKFASPY
                     YRIWQKGAVHFVDYGKHNAFYKIEER"
     gene            11029..11229
                     /locus_tag="TV188_001047"
     CDS             11029..11229
                     /locus_tag="TV188_001047"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534413.1"
                     /translation="MMDTETLEAVYDALQLSLPKIIDMLKAASATRDDAYKEGVLDGA
                     DLIADTVIKAIGQMIDPEADHG"
     gene            11222..11449
                     /locus_tag="TV188_001048"
     CDS             11222..11449
                     /locus_tag="TV188_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534414.1"
                     /translation="MAKDDFLTGFVLTLLAACVFAAGFVIGSDCSSEHYEQQMTDLRM
                     QLVSTQQQLKQSREQNQRQTKRIAELTGNGG"
     gene            11460..12149
                     /locus_tag="TV188_001049"
     CDS             11460..12149
                     /locus_tag="TV188_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002814908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1534415.1"
                     /translation="MEIKCGNCLQLLTELTDGSIDMVITDPPYNISVKNNFATMGRTG
                     IDFGDWDKGFDLLSWIDIASRKLTKNGGMVIFNDWKNLGDIARHCEKTGLVVKDIFRW
                     VKDNPMPRNRDRRYITDSEYGIWVVRKNSKWVFNRKSEKYDRPEYRYPIVAGLEKTQH
                     PTQKPVALMRDIITRHTTKGAVVLDPFMGSGSTGVACLLTERDFIGYELNKDYFNIAK
                     KRIAELTGNGG"
     gene            12153..12335
                     /locus_tag="TV188_001050"
     CDS             12153..12335
                     /locus_tag="TV188_001050"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534416.1"
                     /translation="MPELINTADLQTPIEALENNLDFFKSFYNDERFEDMENAKKLIE
                     RYEKAISILTEVQNES"
     gene            12325..12483
                     /locus_tag="TV188_001051"
     CDS             12325..12483
                     /locus_tag="TV188_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534417.1"
                     /translation="MKVKDLHKVLAKVDPELEVWINEKDGGVITKAKNVMTWNEHPNK
                     FFINAETQ"
     gene            12502..13083
                     /locus_tag="TV188_001052"
     CDS             12502..13083
                     /locus_tag="TV188_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1534418.1"
                     /translation="MNIEEAIKYFEDKRKDYIVSPSVIHVSTVEVINILKQIKLDKPK
                     PEIPQFVADWIEGHKADYITWEKADKADFVFRCINDLFNFGADMHTYDFDVSYEISKW
                     TQEHAYGFIVAVLFGYTIKKEKLYIVEIPNPNSGIEHKHIALARLANGKLGFSEIIDT
                     DFYSREDVRLTESEIRKDFDWAWERGFAKGVKE"
     gene            13080..13247
                     /locus_tag="TV188_001053"
     CDS             13080..13247
                     /locus_tag="TV188_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534419.1"
                     /translation="MNKSEIKNLVDRLSDLIDKCENDFEAMVFNPDGTFDLLLASHSA
                     LSKVLRGEVTE"
     gene            13244..13459
                     /locus_tag="TV188_001054"
     CDS             13244..13459
                     /locus_tag="TV188_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534420.1"
                     /translation="MKSYQKRFVEEYRQLTQRLSKLDKMLKKYAQGTLGFEPDCPIRL
                     LQEQRRVMSEYVDILEARAKFEGVDLE"
     gene            13533..13970
                     /locus_tag="TV188_001055"
     CDS             13533..13970
                     /locus_tag="TV188_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEL1534421.1"
                     /translation="MGNIPTPKANNFLEELKTIPDLIETLERDANLMSRSLIKSPQWS
                     DMRVSGGVKQSQEDKNIKMLHMVSYYSDQIERLKDRRQEMANLIVQSMGICESHVLLT
                     TYLDCDGDYERARERLNIGNRNKYFMFVRRGKESLELILKNTN"
     gene            complement(14475..14852)
                     /locus_tag="TV188_001056"
     CDS             complement(14475..14852)
                     /locus_tag="TV188_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEL1534422.1"
                     /translation="MLIYPATFTQDTDYIMVTFPDVPEAITQGKDFQEAYEMAVEVLG
                     FALEDYTDYPKASSVSDLKEQYRDSDIALIGIDMIAYMKKYHSKKVRKNVTIPEWLNK
                     AAEDENLNFSQVLTEALELKLQA"
     gene            complement(14904..15089)
                     /locus_tag="TV188_001057"
     CDS             complement(14904..15089)
                     /locus_tag="TV188_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEL1534423.1"
                     /translation="MPMTPKQMIKLLKKNGFYEVSQNGSHKKFRDNNGHQTIVPLHNK
                     DLGKGLEDTILKQAGLK"
     gene            15205..15540
                     /locus_tag="TV188_001058"
     CDS             15205..15540
                     /locus_tag="TV188_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEL1534424.1"
                     /translation="MRPQKLTIAGGRRTTVDYDDRSAEYRDYNRNRWKYDRKTKQFYN
                     SKIWRETSKQVLLQSDYICAMCGGEATMTDHIVSVKKDWNKRLDWNNLQASCKACNDC
                     KAIRERRKT"
     gene            15703..16170
                     /locus_tag="TV188_001059"
     CDS             15703..16170
                     /locus_tag="TV188_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HEL1534425.1"
                     /translation="MGRNLKLVETTKKHLTKEEKIVRETAQNKASDGLKKLQKTPPEH
                     FNNVAKYEYRRIIEDLQNLPLRNLDRGLLELYCTWYAIYKETSRKLDEVGYFTNDPDK
                     GIIPSPLILTLEKATANIRSSASQLGLTVDSRMKMFIPKEEEKPKSIFDKFGG"
     gene            16185..17939
                     /locus_tag="TV188_001060"
     CDS             16185..17939
                     /locus_tag="TV188_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEL1534426.1"
                     /translation="MTIEYDYSAIGDIYKDDAFYYAKMVVDEEIKASKKVFKACLRHL
                     NDLKKIDDDNFKFIYLPKKAIDPIIFIELLPDVKTGKPYPLAMFQKFIIGNLYGWRKK
                     TDHSLRRFRKAMISVARKNGKTILIAGILLYEFLFGHNPSMSRQLFCTANDRTQAKIA
                     WDMAKKQLSSLRAKDADVRKATKIVRDELKNLHDESYIRALSRDTGAVDGFEPYVGVL
                     DEFAASKTNEMLELLESGQGQLDNPFILIISTAGMDLNVPMHTIEYPYITKILDEEIV
                     DDGYFGYVAEQDNEGEIKDESNWIKSNPILEVEALHDKLMDYLRTRRRVSLETGEINK
                     VLIKNFNMWRQSSEESYIDKQSWELARIDKPDTHKRRVWLGVDVGRVSDLFAITPVIM
                     MDDFWYIDSFSFVATKYGLTAKEKRDGVSYSNLERQGYCEITTLESGVIDDERVLEKI
                     EEMVYSNDWEVNGICFDPYQFGTLLTMIEKRHPEWPLIEVSQTTMVLNMPTKQFRDDL
                     KNGKIKHSGNPLLTMAVNNAYIKTDNNGMRIDKNKNSNKIDPLDAALDGYAVCYLEPF
                     DGSGYWTSEKILGGETLF"
     gene            17936..18106
                     /locus_tag="TV188_001061"
     CDS             17936..18106
                     /locus_tag="TV188_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534427.1"
                     /translation="MIGFILKNIHTLILLAGLGLLMYGLFLFGDKVGFIASGLILIFL
                     AIYVDSVGGKHE"
     gene            18099..18365
                     /locus_tag="TV188_001062"
     CDS             18099..18365
                     /locus_tag="TV188_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534428.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEVLRNQNRQIAELRSIIQ
                     QNAQATNREFAAVKSATLDNQAAIKKIGDEVYYIKQNYKRKWRK"
     gene            18399..19619
                     /locus_tag="TV188_001063"
     CDS             18399..19619
                     /locus_tag="TV188_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1534429.1"
                     /translation="MSFFQPLGSSKVSYDDYVSSVLAGDVSQKYLGVSALKNSDILTA
                     TSIIAGDIARFPLVKKDVNGDIIHDEDINYLLNVKSTKNASARTWKFAMAVNAILTGN
                     SFSRILRDPKTNQALQFQFYRPSETTVEETDNHEIVYTFTDMLTAKQVKCFAHDVIHW
                     KFFSHDTILGRSPLLSLGDEIDLQTGGINTLIKFFKDGFSSGILKMKGAYISGEARKR
                     ARVEFEKMREGAIGGSPLVFDDTQEYTPLEIDTNVLQLITSNNFSTAQIAKALRVPSY
                     KLGVNSPNQSVAQLMEDYVTNDLPFYFDAITSELGLKTLSDKDRRLYRIEFDTRSVTG
                     RNVDEIVKLVNNQILTPNQGLVELGKQKSTDPNMDRYQSSLNYVFLDKKEEYQDKVGI
                     KGKGGEVNAKEDKS"
     gene            19597..20262
                     /locus_tag="TV188_001064"
     CDS             19597..20262
                     /locus_tag="TV188_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HEL1534430.1"
                     /translation="MPKRINLKGPLIANNSQEVYDYYGMEAASAKSIIEQFPEDNSDI
                     VLEVNSNGGLVTVGSEIYTALRNYKGKVTAEITGMAASAASVAVMGADKVVMSPTAQM
                     MVHKALFKWVSGNSDDLDKASNALKSSDKAIVSAYVAKTGLSEDAIMDLMRNETFMSA
                     QDAVEKGFADEVMSFEAVASIDNSMLPQAVIDDYYRSRNKRKQEISNMLLEIEKEEIL
                     RGL"
     gene            20287..21474
                     /locus_tag="TV188_001065"
     CDS             20287..21474
                     /locus_tag="TV188_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEL1534431.1"
                     /translation="MFEEKIKEIKANIANLNQAIATKTTEVKNALESDDLETARSIKA
                     EIEEAKANLAEAENDLKLYEASVEKGGAENTGGKEVPQETKTYRESVNEFIRSKGTVT
                     NEGLRFEGKDEVLIPLNQTTPVDPKTDGVKKTDVKPVSSEEILYTPAREVKTVVDLKQ
                     FTSIHPAKKESGKWPVLQRATEKMVSVEELEKNPKLGKPQFKNVEWEVKTYRGAIPLS
                     QESIDDADVDLVGIVAETIGQMKVNTTNDAIAKVLKTFEAKAGVKTLDDIKKILNVDL
                     DPAYNVSFIVSQSFYQTLDTLKDKNGRYLLQDSITSASGKVFLGKPVFVLSDDVIGED
                     SAFVGDFKRGVLFADRKDLGLRWADNEIYGQYLQAVLRFGVAKVDDKAGYYVTFKPEQ
                     LPS"
     gene            21619..21921
                     /locus_tag="TV188_001066"
     CDS             21619..21921
                     /locus_tag="TV188_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1534432.1"
                     /translation="MAVSKELLDSVKLYCKIDFDFDDDIIKEMIESAQEQICFAIEDG
                     STPEKFKGHAKFNLAVKKQVKEEYDHRGLSADSFRYPLANGVLNIIHQLRLRGDDS"
     gene            21918..22265
                     /locus_tag="TV188_001067"
     CDS             21918..22265
                     /locus_tag="TV188_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEL1534433.1"
                     /translation="MITRKMNVRITIFSQSGGQNEDGEVVSAVRKDLYTCWAEVLKTQ
                     LRDFNYQSKYQNASNLPTNKDTKVFLIRYNPELSIDNTMFVEFGKRIYKIDKIESDES
                     GKDIIMISGVSMS"
     gene            22262..22639
                     /locus_tag="TV188_001068"
     CDS             22262..22639
                     /locus_tag="TV188_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1534434.1"
                     /translation="MTKGLDEILANLTKLEVKAPKTAKAAVTEVAKEFEKALKANTPV
                     YEIETDERLQEDTVISGFKGANVGIVSKEIGYGKATGWRAHYPNDGTIYQRGQDFKEK
                     TINQMTPKAKQIYAAKVKEGLGL"
     gene            22636..23106
                     /locus_tag="TV188_001069"
     CDS             22636..23106
                     /locus_tag="TV188_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534435.1"
                     /translation="MIAETAAYKLLSNDKTLNELLDRLRGGPFKNGFKQGIFTYDIPD
                     NPVDLRKVDLAPFMRINTTLDGPADYADDEILCNEQRITINFWCKTASEADQISKCID
                     DILKKGGFERYTANEKPRYKDSDIDLLMNVRKYRYFDFYLKERGKNGKSKIWTT"
     gene            23078..23668
                     /locus_tag="TV188_001070"
     CDS             23078..23668
                     /locus_tag="TV188_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1534436.1"
                     /translation="MGKVKFGLRDFQYAVLGEDDNVATKKGGIKKLPGMKSAKLDITN
                     ELVTVSADDGPYVVLSGGITETKLEIEVLDLTTDARKDFFGIKVAAGVEKYNKNLTPN
                     NVACIFRTSDENGKAIWVGLLKGKFNLPGMETQTKEGSPNPKADTVTGNFVSRGTDGD
                     VLVIGREESHEFNYEAFAGFVFAGATDIKKGENFEM"
     gene            23720..24046
                     /locus_tag="TV188_001071"
     CDS             23720..24046
                     /locus_tag="TV188_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534437.1"
                     /translation="MYEITLKKGGVDKVFSKDFINVEDNLLAVEHQVRQSAVFSDEKR
                     RLDSKAHRKLNESYLQMFVDMYAGQFTVDDLKQSDMSVLNTLNDLYIAALGGEQEEDE
                     SEKKEQ"
     gene            24094..24243
                     /locus_tag="TV188_001072"
     CDS             24094..24243
                     /locus_tag="TV188_001072"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534438.1"
                     /translation="MKNGYTILDIKKMRLSDIELMVQALEIETVEKEEVIETTLDKAF
                     PFLFG"
     gene            24256..28179
                     /locus_tag="TV188_001073"
     CDS             24256..28179
                     /locus_tag="TV188_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEL1534439.1"
                     /translation="MGNIGDLVATATLDISPFMSNTRNLKTYMKGLDNSLKAVEKSFQ
                     GHGGRIKGLKAVYAETGSALKGYQELLKTQSQKYSDLKKEIGDVNNATAEQKQKLIGA
                     KSAMLETAAKVTELQNRLRALATETSVFTRFGKAAEKIGGKMKSLGDSVAGVGAAFTR
                     GVTAPIVAGAGYAIKAAVDYETAFAGVKKTVDETATVSYAKLSQGIRQMAKELPASAV
                     EIAHVAEAAGQLGIKTGDILSFSRTMIDLGESTNLSAEEAASSIAKIANITGLTSKEY
                     SRFGSSVVALGNNFATTERDIVAMTNRIAASGKLAGLTNQEMLALATAMSSVGIEAEA
                     GGTAMTQTLSAIETAVINGGEDLTKFAQIANMSSADFARAWKEKPIVALQEFIKGLGQ
                     LDKKGESATKVLDELGLSGIRQSNMLKSLGLASETLGKALGISNKAWQENTALTDEAN
                     KRYETTESKLKMLKNEVNDVAIEFGGPLVDALRNGLEAGKPIIQMAADLAKQFNSLDK
                     EQQQQIIKWGLIAAAAGPALSIFGKGVGIIGSTIQGIGKMSQGLGALSGWLRTFKTGA
                     AAASAGAEAATASMGGMAGAVALLSNPVTWGVLLGGAAIVGIGLIADSMYKAQKRTEE
                     WGTAVSATEANALSNFKKKVDETNTSLQMFEAGAGSVKKVTEAFDDLVGSIEKLAQSK
                     LDKNINLAKKLGLSEETINALKSKTESVVNNVKSMNTQIKAIMEKHNGDMSQLSSAEK
                     ELVLRNQREMITAQLDLMKFSASEKKALTAALNNELDALNARQLEKVSENTVKMLDKE
                     NSAYKTKKAELKEILKQFGSDTSKLSAEELAARQEVLNRLTELNMQHNLKTKALNDQY
                     LAIQRERVQRLKESGKSQEEIHQGISQMASDMAQKLGISYDDAYRKLAYYTEKSGETL
                     KVLSRNTANATAEVAAANAQWDSLFTSDNPQQSLNELLSTAEGWNSFEIMVKNADVEP
                     TGRAALAEMLVAGGQWENMTLEQKKLVVDGQQAMIEIFDSKELLAQWQALTPEEKVLL
                     AKNLTQEPTMSAQQALDSVKQTVPADVNASDKTAGETQSAQNKIDNVKQRVPADVKAS
                     DKTGPDVASADRAVNSPKQKSPAVIRAQDNASGVAEGVIGALARIPRSVTTTITTFVR
                     KIFGHEKGTDFHPGGLAMVNDQKGPLYKELVTLPTGESFIPSGRNVILPLPRGSKVLK
                     ASRTKQLFPHYASGIGFDDTKIASLTTRLKSVQDKGQVIINTDPQLAELIKLLKDRDD
                     RNVTNNYTVNATNSSSSEDMFSQENMRRLLRELAYYTNGEGGRLA"
     gene            28179..28886
                     /locus_tag="TV188_001074"
     CDS             28179..28886
                     /locus_tag="TV188_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1534440.1"
                     /translation="MRYIEFNGTKSNDLGLLLERERSIKSTNNDIDLIEVAGRDGVLI
                     KDNERLKAVEQDFPFSLVGDVTVNQQKISEWLHVKGWHDLALSWDKDYIYRASVVNLF
                     EIDEILKQFGRLKVNFLIHPIKYLKTGKQEVPLVNGGTLQNPGNVQAKPILKIKGTGN
                     GVLTINDFETGLENVQGELVIDMERHLVYKDVLSAWDNIVRTEHHRMPLFDIGQNKIS
                     WTGNFTITAVPNWGVKV"
     gene            28883..>30591
                     /locus_tag="TV188_001075"
     CDS             28883..>30591
                     /locus_tag="TV188_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1534441.1"
                     /translation="MIPVLYEAKETKFRTFGLGEIADAYEVKATRERNGNYSLYIKYP
                     LDGAFAHLFKEEMKIKSDAGRRTKWQTFEINRVLRNSKEHIEIFARHISMRTQDIALK
                     PFVSGSSIDAESALEVWRDNLVGDDTFDVKSDILTLGSFNWEVDKIGNARGALGGVAG
                     SILDVYGGEYEFDNRTIILHKQMGRKTPTVLEYGRNIVSVEEERLLDGNYTSIYPYVR
                     YTPQPKPQEEASGKPHIGEHEKPEEQLVTLPEFIIDGQYLDLYAQRRIQMVDLSSHFN
                     DDKKEPTVEEIRKLAQKYLKDNNVGAPKISIEVDYIDLSQTLDYQDFRVMEEVELCDI
                     VPLYYPKFGITTETEKVVEIVYDVYTDSNHTIKLGTIGQSISKSLTGGVTQRIETLEN
                     NQKVITNNQQQFELNLPKYLNDLNGTKIWYEKPDDNVEHKIGDFWFEKNGKYQRTWVW
                     DGNQWVKIIDTEDLNPNQRAFDEAMAEIEKLKQHQQQIDKRNQRELEEFRDTLKNLAL
                     PEEAIKKITEAIKVDDIPSIKQSFDDLKNKVSETSETARLNAEIIGTDGKTRYNKNLL
                     VGDP"
BASE COUNT        10634 a         5085 c         6660 g         8212 t
ORIGIN      
        1 tggaaggagg aacgatatga acgaactaga aagaacagcc cttaatgaaa tcatgaggac
       61 agtgacttat atagcggaga agctggataa aattgattct aagatttctc agtctgtaga
      121 agtgaacgat agtgcatcgt cagcgtcgta gtctgccgca acaaattgag cagctgctaa
      181 aataaaacgt ttgagatcct gcaagtcttt attattatgt ctacgaacat aatgagtttc
      241 atcgttacca atccacgcca ccgagcgaga tagagcttgg agtttaggga agtcggagag
      301 atagtcacta attacttttc caagcataat ttgtttgatg ttgtcgctgt cgtcaggatt
      361 ctttgatatt gtataatctt tgattaaaaa ctcagcagct ttacggtaac caacacctgc
      421 aatttgatcg agtttttctt gctctgcaat tgtagcttgg gagtatatct ctacaaatgc
      481 tggcgacact ttatcaacgt tttcaggaag attcactcta ataggtggac gatagaagta
      541 ggcgacagct gatcctttac caatctgatc gtggatatac tctacagcaa aatattttaa
      601 gcaatcatcg aaagagcaac ggaatatcac tgaaaaatgc ccctgatatg aataactttc
      661 attgtcagaa cttttgcttt cgccaacgtg ttgaggggac atagttcgac cacagtgggg
      721 gcaagtcgaa ggtgtatcaa tcgtgattgt acttctacga tctctaaatt gtataactac
      781 atcaagcaac attattattt ctctccaatc gttttattta aattatacca cagaaagggg
      841 gtggggaaga tggaagaaac agcctcagta aacgtaactg taaaaattaa taacataact
      901 gagttttcaa ctttagttga aaagttcaac gaaaaagccc gtgagttaga agcgatttct
      961 cacgagctaa tgcgtttcaa atttcaaggc gagattgaaa gtcgtgcgct atcagataat
     1021 gctaacgaaa ttgaataatt tatctttatc aattttaacg cacggtaagt aactataatt
     1081 ttcgacatat cgaaaattat aggcaaaatt agtatttttg atttcttttt caaattttgc
     1141 aaaatccgct tgggatagaa gtttgaaaat ataagctctt actcttgtta tgtcggtaag
     1201 cattgagagt gtaccaattt gccctgattt taagtttaag atgctcaaga tctcagtaac
     1261 atcaatactt ctgtggtttt ctagctcttc atatgagccg agttcatact cataaaagca
     1321 gcaatgccca acttcttgat atgtattgaa agtcacaaag tctccgttga attcaaaaac
     1381 tagtttgtca ttaagcatat tttctttgat gtcaatatgt actctatcaa caagatatct
     1441 atgacaagct tccaataatc gaacttgatt taaatccatc acattcacct cctttctgcc
     1501 catattatag cagattagag gtactaaaaa cagatagaaa ggaggtgggg gaatgcagat
     1561 tcttctgtat aaactgcgaa aagaaaaaag aatttcacaa gaagagatgt ctaaggttat
     1621 taataagtct tctaacactt accgagataa agaattaggt aaaagagact tcacacagag
     1681 tgaaatgttt aaaatcgcca atttctttca caaagaatta ggcgaaattt ttacaccata
     1741 aacttcacga aacgtgaaat ataaatcaac acaacactag aaaggaacaa catgaatcaa
     1801 ctaataaaca tcaccctaaa cgaaaatcaa gaaccagttg tcagtggtcg tgatttacat
     1861 aaagtacttg aaatcaaaac agcttataaa gattggtttc caagaatggc tgaatatggt
     1921 tttgaagaag gtcaggactt tagctcattt ttgagcaaaa gtacaggagg tcgtcctagt
     1981 caagaccacg ttctaaaact agacatggca aaagagattg ctatgttaca gcggaatgaa
     2041 aaatctaagc aagtccgcaa gtattttatt caaatcgaaa aagactttaa cagccccgag
     2101 aaaattatgg caagggcgtt gctgatggcg gacaagaaag tgcataaatt agaagctcag
     2161 attgaggctg accgacccaa agtactattt gctgatgccg taagtgctag caaatcatct
     2221 tgtctgattg gtgagttagc taaaatcctg aaacagaatg gaatcaatat tggtcagaat
     2281 aagctatttc agtggcttag aacgaacggt tatctaatta gcagacgcgg cgagtcatgg
     2341 aatcagccaa cgcaaaaaag tatgcagctt ggattgtttg aactcaaaaa aacagccatc
     2401 aatcactctg acggtcacac tacaacaaat gtaaccccaa aagttactgg taaggggcag
     2461 cagtatttta tcaacaaatt tcttaaccag gaatatctgc cagtttagaa aggaaaccac
     2521 atgagaccaa aacgatatcc gtatacacca aaaagaccct ttccgagtca agaaagagtc
     2581 gcaagttata gattggctat tgaagagtta aattctttag caccaacagc atccgaaaca
     2641 ctaaagaaaa aaatagaaga agctaaaaaa tatcatttga gttttctgaa gccttttgat
     2701 cttgattttc ttctaaacga gcaagaatct cagcttcatg ttgaataaga attttttgaa
     2761 tatgttcctg gacttcacga actctaactg gttcgaactt acttctatca cgaaccaatt
     2821 caataatttc gtcgatttct ctttgaatat aacgaccagg aatatattta tcaaccatgt
     2881 aatttatcct cctttatagc atatttgact aacgacttca taaggaatag atggtttgtc
     2941 ataaatcaat tatagcagaa agagggggca tagaagaatt tatatacaac aaaaaagtcc
     3001 gacgggaatc ggactcaaaa caaaaactat ttacttagat tataacacaa gagagaggaa
     3061 ggttccatgg caattgaggt atttggacca gatttcagaa aggaactact tgcagacttg
     3121 atttctctaa acagagaagc gctaaaaatt gctcaattcg agaactctaa gtcaattgag
     3181 tgggttacca tgaagcggtt ggaaaaagaa actggatggg ggcgaactaa attgacccag
     3241 tggagagaac aagggaaatt taactttaaa aggtcatcag aaaacgggaa agtactatat
     3301 gacctagcag atgttaatag atttttgcga acaagtggat atgaaaaagg agcataacat
     3361 gaacaaacta gaattatttt tattagcagc aaccgtcatc ttagcaatca ttgcaagaat
     3421 tcagtatgaa gtcataaaaa aacataattc gcccgaaaat aagcgaaaaa tttttaggga
     3481 agtagcttta gaaaacagca aaagatggag cgagaagcgc tctagaggag aggtagaaaa
     3541 atgccttttg taaaacggta gaaaccacat agtcctttga caactgaata gggtaccttg
     3601 aaaaaatatt aaaaaagttt gattttgggg ttgacttatg tatccacata atgatattat
     3661 atatttgtgg atacgaaagg aggaaatatg accactacca aaaaacttgg tcgtccaact
     3721 tctaatccta agtctcatag caaaagactg agaatgacag acgaagaagt acaaaaatta
     3781 gaatattgta ctaaacaaac tggaaaaact cagacagatg ttttgatgct aggcttagat
     3841 aaggtctatc aagagctaaa aaaatagcgt ataatccgcc atcgccaaac tttggattac
     3901 acgctatcga ccgacctgaa aacaggtaca caaatatatt atcatgtgta cccttttcag
     3961 tcaacctgac aagggtattt tttgcgccct tgttgtttag ataagggttt ttattgtacc
     4021 caaaaatagg aggaacacaa tggataattc aaaactagca aatcatcaaa aagtaacggt
     4081 agtctgtaca gattttaatg tctatttgaa tggaatacga cttactggag ctagaccaga
     4141 aaccgctaaa ttagctgaga gatgcggaga gaaactcatt acactaagtc tagtagttac
     4201 agattttgat gaccatagaa cacctaagat ggcggatatg gcaaaggagg ctgagatggc
     4261 taataaaaca ttggactggg agaaaaagca tttctataaa tctaataaat aatgtatctc
     4321 agagcgttat agattgattc tggattttgc gaaactccaa attcattaag ccattcgata
     4381 acctcggttt ctacctgccc gatatatcca agaaaataca tgccttttgg tgtcagaccg
     4441 tcaattgtat atattcgtct atctaatctc ggcatttctg tggcagtaac taaatcttgt
     4501 tggatcaaac aatctagggt gtaaaaaata atttcttcaa cttctcgata agggtattga
     4561 gaatatatcc tttttccttc ttctgttgca ataaggtatt gaagtaaatc tacacccgta
     4621 tccaacttat gatatccgat ggcttcaagt gaatttttgt ataaagaata gtaatcaatc
     4681 atacacttct ccaagtattt tattttaaat ataacaaaat agtaagagga aaacaatatg
     4741 gctaaaactt acacattaac cgaagaagaa ttgaatgaat tagtagctga gcgcatgaaa
     4801 caagcgaaag aaaaacgcac accacaagga ctattcaaag atgtcagctt tgatgatgag
     4861 ttgattccaa tcaatgaaaa atatccaaaa gtactcaaga aattaaatcg tgaacgtgct
     4921 tataaaccag aaaaacacgt cttcaatcag acaccaaaag tttttggtgt ggacaacgat
     4981 attagttata gcaaaattac aacacatgac gtacacaacc atattcgttt gcttgtccta
     5041 aatgtctttg gtaaaagtca aaataaggaa gtattgcccg aggaatatga ccaagcaata
     5101 gagctttaca aggaattgaa agaatggttt gtgtctagct atgataagcg attagaggga
     5161 ttggtgctag aagatgatta aaaaattctg cgttaactac ttactaagac agattaacaa
     5221 aagcaaacta gaaacaagag ataaagcgaa gttaaaccac tttatcacac tagtggacta
     5281 caagttagga ggataaattg ggtaaagaaa aaactaaaat atacttttgg ctaaagttcg
     5341 acaagaagtt ttttgaaaat atttttatca aacgtttaaa aaagatggct ggcggagaca
     5401 ctatgacagt cttgtatatt cgtttgatgc tagaaagttt agaaacagac tgcattttat
     5461 attacgaagg atactttgaa aatttggtag aagagcttgc catcaagtta gaggtgtctg
     5521 aagacgatat caatatgaca ttagcttact tcacaaaatg tggtctaatc cagatagacg
     5581 gtagcggtaa cgcacaaatg ccccaagcta aagctatgct ggaaagtgag acgaactggg
     5641 caaaatataa acgagaaact agaaaaattg gacaaattcc aaccaatgtc caaccaatgt
     5701 ccaaccaatg tccaacagag atagagatag agaaagataa aaagaaagat ataaatatag
     5761 atataaagtc agaagtagaa gaagagataa aagagatttc tactgctgac gaaaacagtc
     5821 tcaaaattat atctgattat ttccaacaag aaatcggtat tttgtctcca aatcagtttg
     5881 agcagctgtc agactatatt accattacaa aaatggaggt agatgttgtt aagtctgcta
     5941 ttacaagagc tgctgacaat tctaaacgtt cttttggtta tgttaactct atactgcgca
     6001 attggcgaca aaatggaatc accacaatgg taaaagtgaa agaagaaagt aggaatttta
     6061 aagccagaaa agctaagcaa gaagaggtct cagaatatga cacttggtga caacaacgca
     6121 cttgctaaaa tcgctgtagc ttatcaaaaa aatgtcaaaa aagaaagcac tgtttgtcaa
     6181 aaacatggtt gcatctatat cacaatcctt aaaactggat tgacagtatg tccgatgtgt
     6241 cacaaagagg acttagaaag ccaaaatgag ttacacgtcc aaaagcaata tgagagagag
     6301 cttgaaaaca agcgactgta ctatctcaaa aaattatcaa ttatggacga cgagttggaa
     6361 aatgcctcat ttgataattt cagggtgatc acacctaagc agcaagaggt cctttcgtgg
     6421 gcaaaatcca tggctaatta ctggtataca ggaggcaaag gcaatatcat catgactggt
     6481 aaagctggcc gcgggaaaag ccatctagca tacagcatca tcagaggttt gtctgacgag
     6541 actaaaaagt tagggctgct tgtaaacatt actgacttgc tatcagagat aaagcgagac
     6601 tttagccaag aggcattttg gctagataag ctaaaaaatg ttgattattt ggttttagat
     6661 gacttaggcg ccgaaaaggt cagcgactgg tccacaagta ttatttacag cttactaaat
     6721 aagcgtacaa atacaatcat tactacaaac ttaacacctg ttgaaataag gaaaaattat
     6781 ggagaacgta tcgcatcaag aattagaaaa ggctgcgcta agagccatat tatggatttt
     6841 gcaggactgg aagatgagag gatcaagcta tggaactaat attaataact ttttttggcc
     6901 tatctgaaga acatgcagcc aaaatcatgg cgctagacga agatagccga ataaataaaa
     6961 tcgaggaatt gagagcatgg agagaatgct caaaaataac attttaggag gaaatatgac
     7021 accagaagaa gcagaaaaag caaaaatcag agctaaacaa gaaattgaag tttttagcat
     7081 ataccttgaa caggcgattg atacttttgg cagcatgcta agcccacaag aagtcttctt
     7141 ggcagcaggg tttgcctacc ttggcgctgg tcaaacagac atacatgcgg ccgtcgaggg
     7201 gttgtatgag caagttcgat gactttaaat ttagcgaaga ctgggagagt aactactttg
     7261 aggtccaagc tttgctagga caagagatag acaagctaca aaatagagtt gtccagttag
     7321 caaacgaaaa taatagatta aaggccgaaa attggcagtt aagacacaga aagaggaaat
     7381 gaaatggcga atcaattatc aacatacaca cacaaacaat tttttaatgc accaacaatt
     7441 caaaaggctt ttgatgacgt ttggaaaggc gccgggacac agttcgcagt aagcatcttg
     7501 tcagtactac aaggtagtaa aagtttgaaa tcggcatcta atgaatctat ttatgcagca
     7561 gctatgaaag cagccgtgtt aaatctgcct attgagccaa gcttaggaag ggcctattta
     7621 gttccgtaca aaggtcaagc acaattccaa ttaggctata aagggttgat tgagttagcg
     7681 cagcgcagcg gacaatacaa aaatattaat gcaggtatcg tctataaatc acaattaatt
     7741 tcttacaacc ctttgtttga ggaattgatc cttgacttta gtaagccaca agatgaaatt
     7801 gtagggtatt ttgccgcttt taaactttta aatggattcg agaaagtttc tttttggaca
     7861 gtagaaaaag taactgcaca tggaaagaaa ttttcaaaat cgtttgctag cggcccttgg
     7921 aaaacagact ttgatgcaat ggctcaaaaa actattttaa aagatatttt gagtaaatat
     7981 ggtccgttat cagttgagat gcagaaagct atcgatgaag acaatcaaga ttcaacaatt
     8041 tctattccga aagacattac accaccagaa acaaacagcc ttgacgacct aattggtcac
     8101 cagaacgaaa aaaaggacgc tcctggcaat ttaaaagacg taactgatga tttacattcc
     8161 gagccagaaa aaacgctcac agacgaaaat aagacggttt tagaagacac ctcttatcca
     8221 gctgatgaaa tccctgattt tgaccaagaa acaggcgaaa ttaaagctag cgaaggcaac
     8281 ctctttgata atcttggaga cttaatatga ttaaacttgt aaaaattgaa ggatattata
     8341 ttaatccaga atatgttgtt ggcgtttggg aaagatctgc tttaaatttt gacgatttag
     8401 atgaaaaagt agtggttatt caattcgttg gagataggga aagggaagag tgtgtctttt
     8461 acgatacacc tattgatgaa gtaattaaga ggttgctaga tgactagttt agacttactt
     8521 ggaaaggact attatagcaa ggaatcagct ataagatact ggtccattag tcagtacaag
     8581 cgctttagag aatgcgaggc aagggcactt gctgaattac gaggggattg gacagatacc
     8641 agagataaca ctgcgttgct cgtcgggaat tacgtccact cttactttga gggtgaggag
     8701 gctcacgaag aatttaaagt ccaaaacagt tctgaaatga tttcgaccag aggaacgaca
     8761 aaaggccaat taaaaaagga ttacttagtc gctgagcaga tgattgacgc tcttaaaagc
     8821 gataacaact tcatggcaat ctaccaagga gaaaaggaag ttgccatcac aggatttctt
     8881 ggtgaggttg agtttaaagg taagattgac tgtctgaatg ctgaacgtgg ctattttgta
     8941 gacattaaaa caacaaaagg acctattgat gacaaaattt ggaatggtca agagcgagtt
     9001 tactggtttg aggcttacag ctatattttg cagatggctg cctacaaaaa catgctagag
     9061 gcaaaacaca aaaagccgtt tgagcctatc atttacgcag taacaaagga aacaccgcca
     9121 gataccagag caatcaggat tcaaaattta gatgctatgc aaaatgagtt agacaaccta
     9181 gctcaaaaca tcaagcgttt agatgatgtt aaaaaaggca tagaaaaatc taagccttgt
     9241 ggtcattgcg agtattgcag ggcaaatcaa ttaacacaaa gggtaatgat tttttaacta
     9301 actattgcaa agtgaagctc ggcctttgca ataatcatat tttccgagcg agaaaggaaa
     9361 attgcaatat cgtcaagtta acagtattga tgatataaag agttgctaca ctcgtccttg
     9421 ccaatgctca cacacaattt tagggcgagt gtggatttta aaaaaggtga aaaatatgga
     9481 acaaattaaa attacaggaa caggaacagc actaatttta gatagagtaa accgaatctt
     9541 tgccatctct ggcggtttga ctatgcaatg ggattttatt agtgatttta aaaagattga
     9601 cgacgaaccg tcacttgatg aagatggaga actattcgaa gtagcttacg accttgtgct
     9661 tgaagctaaa cccaaaacta aaatcaatct aacatcatca tattttgcta aagagcataa
     9721 gaaagacaca gacgaaatta taaaagtatt ctcgtttatc gaagataata agagaaatat
     9781 ctttgaaacc cttggcattc gtggggtgct tgaatgagca atctagtatt atcgctagac
     9841 atctcaactt ctggtacagg ttgggcctta tttaaaggct cagaccttat ccagagtggt
     9901 gtcttaaaac ataagagcga ctcttatttc gaacgtggac gatatatggc tagccaatta
     9961 agagctatcc agtcacgagc actaaaaaaa tacgattgct cctttagcac aatcgcagtc
    10021 gaaaaaaact cggttatggg tccaaatcaa caatccatgc ttaaaatcgg cattgtaact
    10081 ggtatcatct taggacgatt gatagctgat aatgtcgtat ttatcaatgt ctcaacttgg
    10141 cgaaagcact ggaagtttag ctacaaagac cgctcaaaaa aagcaatgaa agcacagtca
    10201 aaggctaagg ctgctgaaaa ctttggcaaa atagtcaaag atgatgaggc agatgccgtc
    10261 ttgattggtg catactatgt caatcaaggc tatcttgatg gattggagac acatgactac
    10321 tactaaaaaa cacgttgtga ggatttacaa caaaggtatt acagcgactt acgcggttac
    10381 tgataaaaga ttgtttaggg agcatgagtt cgcaacaaaa agagaagcga tgcagtttat
    10441 tagagagcta gagttagcta atgataagcg agcgacagaa tattatttga gagagtggag
    10501 agatgctaat ggaagatacg tttaaaaaaa ttaaggagct tgaagctgct tgtcaggata
    10561 ggacagataa cattaaaaag ccatcacact atcaagggcg gcatggcatg gaagcaatcg
    10621 acgtggttaa aaacttcgca gcttgcccag agcacgagga gggtttttat tggggcaatg
    10681 ctgttaagta ccttttgcgg tatcacgcta aaaatggtgt tgaagacctt aaaaaagcac
    10741 gtcagaacct tgattggtta atcgagaagt tggaggaagt ggaatgatac caaaatttag
    10801 agtgtggaag aatgagtttt agattatctt gggaaattaa cggccaaacc gttgaggtta
    10861 taggtgacta taaaacacta aaagcagcct atgactcaat taaggtccac gtcaaagaca
    10921 gagataaatt tgccagccca tattatcgca tatggcaaaa aggagctgta cactttgtgg
    10981 attatggaaa acacaatgct ttttataaga ttgaggagag gtgattaaat gatggataca
    11041 gaaacactag aagcagtata tgatgctttg cagctatcct tgccaaaaat aatcgatatg
    11101 cttaaagcag catccgcgac cagagatgat gcttacaaag agggtgtact cgatggcgcg
    11161 gatttgatag ctgatactgt aataaaagct atcggacaaa tgatcgatcc ggaggctgat
    11221 catggctaaa gacgactttt taacaggttt tgtacttaca cttttagctg cttgcgtttt
    11281 tgcagcagga tttgtgattg gatctgactg tagtagcgag cactacgagc aacaaatgac
    11341 agacttgcgt atgcagcttg ttagcacgca gcagcagctt aagcaatctc gtgagcaaaa
    11401 ccagagacag actaaacgga ttgcggaatt gacaggaaat gggggataaa aaacactaca
    11461 tggaaataaa atgtggaaat tgcttacaat tactaacaga gttaactgat ggatcaatcg
    11521 atatggtgat aacagaccca ccatacaaca tatcagtaaa aaataacttt gctacaatgg
    11581 ggcggacagg tatagatttt ggtgattggg ataaaggctt cgacttgtta agttggattg
    11641 atattgcaag tcgaaaatta actaaaaatg gtggaatggt gatcttcaac gattggaaaa
    11701 atttaggaga tattgcaaga cattgcgaaa agacagggtt agtagtaaaa gatatttttc
    11761 gttgggtcaa agataaccct atgcccagaa acagagatag aaggtatatt acagacagcg
    11821 agtacgggat atgggtcgtc cgaaaaaatt ccaagtgggt atttaatcgg aaatcggaaa
    11881 aatatgatag gccggaatac agatatccaa ttgtagccgg actggaaaaa acacagcacc
    11941 ctactcaaaa gccagtagcc ctgatgaggg acatcattac gcgacacaca acaaaagggg
    12001 ctgttgtttt agaccctttt atgggtagcg ggtcaactgg agtagcttgt ctactgacgg
    12061 agagagactt tattggatat gagctaaata aagattactt taatatcgca aaaaaaagga
    12121 tagcagaatt aactgggaat gggggatgaa atatgccaga attgattaac acagccgact
    12181 tacagacacc gatagaagca ctagaaaata acctagattt ttttaaaagt ttttacaacg
    12241 acgaacgctt tgaagatatg gaaaatgcaa aaaaattgat tgagagatac gaaaaagcta
    12301 tatcaatttt aaccgaggta caaaatgaaa gttaaagatt tacataaagt gttagctaaa
    12361 gttgaccctg aacttgaagt ttggataaat gaaaaagatg gaggggttat aactaaagct
    12421 aaaaacgtga tgacttggaa tgagcatcca aataagtttt ttataaatgc agaaacacaa
    12481 taatgttaac cgaggtacaa aatgaacatc gaagaagcga taaagtattt tgaagataag
    12541 agaaaagatt atattgtatc accaagtgta atacatgtat cgactgttga ggtcataaat
    12601 attttaaaac aaattaagtt agataaacca aagccagaaa ttccgcagtt tgtcgctgat
    12661 tggatagagg gacacaaagc agattatatt acgtgggaaa aagctgataa agcagatttt
    12721 gtttttaggt gtattaatga cctctttaat ttcggtgcag atatgcatac ctatgacttt
    12781 gatgtgtctt atgagatatc aaaatggacg caagaacatg cctacggttt tattgttgct
    12841 gttttgttcg gctacacaat aaaaaaagaa aagctgtata ttgttgagat ccctaatcct
    12901 aatagtggca tagaacacaa acatattgca ctagcaaggt tagcgaatgg aaaacttgga
    12961 ttttcagaga tcatagatac tgatttttat tcaagagaag atgtccgact caccgagtca
    13021 gaaatccgca aagattttga ttgggcttgg gaacgaggtt ttgcgaaagg tgtgaaggaa
    13081 tgaataaaag cgaaatcaaa aatttagtag atagactaag tgatttaatt gataaatgcg
    13141 agaacgactt tgaggcaatg gtatttaacc cagacggaac gtttgactta ttactcgcaa
    13201 gccattctgc gttgtcaaaa gtgttaagag gagaggtaac agaatgaaat catatcaaaa
    13261 aagatttgtt gaagagtaca gacaacttac acaacgtttg tcaaagctag ataaaatgct
    13321 taaaaaatat gctcaaggca ctcttggttt tgaaccagat tgccctatca ggctattaca
    13381 ggagcagaga cgtgtgatgt cggagtatgt cgacatattg gaagcaagag caaaatttga
    13441 aggggttgat ttggagtaat aaaaaaagac gtccatgcga acgccttcat gattaaatac
    13501 ccaacaatat tatatcatga atggagagtt agatgggcaa cattccgaca ccaaaagcta
    13561 ataatttttt ggaagaatta aagactatcc ccgatcttat agagaccctt gaaagagacg
    13621 ctaacctaat gagtcggtcg ctcattaagt ctcctcaatg gtctgatatg cgagtgtctg
    13681 gtggggtcaa acaatcacag gaagacaaaa acataaaaat gttacacatg gtcagttatt
    13741 acagtgatca gattgagcgg ctaaaagacc gtcggcaaga aatggctaat ttgattgtgc
    13801 aaagcatggg aatttgtgag agccatgttt tgctaacgac ttatcttgac tgtgatggag
    13861 actacgagag agccagagaa cgcttaaaca taggtaatcg gaataaatac tttatgtttg
    13921 ttaggcgagg aaaggaaagt ctagaattga tactaaaaaa tactaattag atacaaattg
    13981 atactacata atactaataa ccatgttatt atagtactgt tgaaataaca agaagagata
    14041 accattttac caattgacta tttatttagt cgctgacttt aactacgatc aaacttgtta
    14101 ttttactaaa gcttagtagc tttgcgttaa aggtgttaaa ttactcggtt gaaccggtcg
    14161 ggtaagtcgc aaatatgaag agagttgttg agacgtaagg aaatgtcatg tgcacgcatc
    14221 ttatgatatt gcaggttcga accctgccgt ctcaatcagc gtcggggaga cgcgacccca
    14281 taccccttta aaggcagaca cgttctgatg tgtgggtttt tatgattaac cgcaagtcca
    14341 aaaccaaggg tcgcaacctt gcttgtggtt agtagggaca acggttgtaa gtcggttcga
    14401 ttccgactgt tcctgtgcta gtcatcacat cgtgatggct ttttattatg caaaaaagaa
    14461 ccactaagtg gctcttatgc ttgtagtttt aattcaagtg cctctgtgag gacttgcgag
    14521 aaattgagat tttcatcttc ggctgctttg tttaaccact cagggatagt cacgttctta
    14581 cgtacttttt tagagtggta ttttttcatg taggcaatca tatcgatgcc gattaaagca
    14641 atatcagaat cacgatactg ttcttttaag tcggaaacgg agctagcctt tggatagtca
    14701 gtatagtctt caagagcaaa gcctaagact tcgacagcca tttcgtaagc ttcttgaaag
    14761 tctttacctt gagtaattgc ttcaggtaca tctggaaatg taaccatgat atagtctgtg
    14821 tcttgtgtga atgtagctgg atagattaac ataatgattc tccttcgatc actgtgagat
    14881 aagcaaacca tctggcaagc ggattatttt aaacccgcct gctttagaat ggtatcttca
    14941 aggccttttc cgaggtcttt gttgtgtaga ggaacaatgg tttgatgtcc gttattatct
    15001 cggaattttt tgtgacttcc gttttgactg acttcataga acccattctt ttttagcagt
    15061 tttatcatct gctttggggt cattggcata ttgcttacct cactttctat acttatatta
    15121 tacacgcaat aaacatggtt gtcaataggt atgcgcaaaa aatgcgtatt tttgttttct
    15181 attttttatt atggaggtta gggtatgagg ccgcagaagt taacaattgc gggtggcaga
    15241 cgaacgactg ttgactacga tgataggtca gctgagtatc gtgactataa tcgtaacaga
    15301 tggaagtatg ataggaagac taagcagttt tataactcta agatttggag agagacaagt
    15361 aagcaagtct tattgcaaag tgattatatc tgtgcaatgt gtggtggaga agcaacgatg
    15421 actgatcaca ttgtctcagt taagaaagat tggaataaaa gattagattg gaataacttg
    15481 caagcaagtt gtaaagcttg taacgattgt aaagcaataa gagagagacg gaaaacctaa
    15541 acgtacataa aaagtaacat acgcaatcat tgttcgggaa ataccccgcc tattttttaa
    15601 cggggctata ttgttcggaa acttaagaac gcgccctttt ctgtgcaaaa aaatcccttt
    15661 ttgaaatttt tgaaactgta aagtttgtgt aaaggaggtc ttatgggaag aaatttaaag
    15721 ctagttgaaa cgacaaaaaa gcatcttacg aaagaagaaa aaatagtgcg agaaaccgcg
    15781 caaaataagg cgtctgacgg tcttaaaaag ttgcaaaaga cacctcctga acactttaat
    15841 aatgtagcta agtacgagta taggagaatc atagaagacc tccaaaacct acccctaaga
    15901 aatctcgata gagggctatt agagttatat tgcacatggt atgctatcta caaagaaaca
    15961 agtagaaaac tagatgaggt tggttatttt acgaatgatc cagacaaagg cattattcct
    16021 agtccgctta ttttaacatt ggaaaaagcc actgcgaata ttagaagtag tgccagtcaa
    16081 ttaggactaa cggtagatag tcgcatgaag atgtttattc cgaaggaaga agaaaaacct
    16141 aagagtatat ttgataaatt tggaggatag agagaaaggg ggtcatgaca atagaatacg
    16201 attattcagc aatcggcgac atctataaag atgacgcttt ttattatgca aaaatggtcg
    16261 ttgatgaaga gattaaagca agtaagaagg tctttaaagc ttgtctaaga catttgaatg
    16321 accttaaaaa aatagatgat gataatttta aatttatcta tttaccaaaa aaagcaattg
    16381 accccataat ttttattgag ctattgccag acgttaagac gggaaagcct tatcctttag
    16441 cgatgtttca gaagtttatt atcgggaatt tatacggatg gcgaaagaaa acagatcatt
    16501 ccttaagacg ctttagaaaa gctatgattt cggttgctcg taaaaatggc aaaacaattc
    16561 tgatagctgg tatcttgctt tatgaatttt tgtttgggca taatccatct atgagtagac
    16621 aattgttttg tacagctaat gaccgtacac aggctaaaat tgcttgggac atggcaaaga
    16681 agcaactctc atctttaaga gcaaaggacg ctgatgtcag aaaagccacg aaaattgttc
    16741 gtgatgagct gaaaaactta catgatgaat cttatattag ggctcttagt cgagatactg
    16801 gggcagtcga tgggttcgag ccttacgttg gcgttttaga tgagtttgcg gcatcaaaga
    16861 caaacgaaat gttagagctt ttagaatccg gtcaaggtca gcttgataat ccgtttatct
    16921 tgattatctc aacagctggt atggatttga atgtccccat gcacacaatt gagtatccgt
    16981 acatcactaa aattttagac gaagaaattg tagatgatgg ctattttgga tatgtcgcag
    17041 agcaagacaa cgaaggtgaa attaaagatg aatcaaattg gataaaatca aatccaatcc
    17101 tcgaggttga agctttgcac gataagctaa tggattacct gagaacgcgt cgtagagtgt
    17161 ctcttgaaac aggtgaaatt aacaaggtac ttatcaaaaa ctttaacatg tggcggcagt
    17221 cgagtgagga atcatatatt gataagcaat cttgggaact tgctcgtatt gataaacccg
    17281 acacacataa acgaagggtc tggctaggtg tggacgtcgg tcgtgttagt gacttatttg
    17341 ctattacacc agttattatg atggacgatt tttggtatat tgacagtttt tcttttgttg
    17401 cgacaaagta tgggttaacg gctaaagaaa agcgtgatgg tgtgtcttac agtaatttag
    17461 aacgtcaagg ctattgcgag ataacaacat tagaaagtgg ggttattgat gatgagagag
    17521 ttttagaaaa aatagaggag atggtctatt cgaatgactg ggaagttaac ggaatctgtt
    17581 ttgaccctta ccaatttgga acgctgctta cgatgattga gaaaaggcac ccagaatggc
    17641 ctctcataga ggtttcgcaa acgacaatgg ttttgaacat gccaacaaag caatttcgtg
    17701 atgatctcaa gaatggcaaa ataaagcact ctggcaatcc attgctaaca atggctgtta
    17761 ataacgctta tatcaagact gataacaatg gcatgaggat tgataagaat aagaatagca
    17821 ataagataga ccctctggac gctgctttag acgggtatgc agtttgttac ttagagccat
    17881 ttgacggctc tggttactgg acaagtgaga aaattttagg aggagagaca ctgttttgat
    17941 tggttttatt ttaaaaaaca tacatacatt aatcttgtta gctggactag gtttattgat
    18001 gtatgggttg tttttgtttg gtgataaagt tggttttatc gctagtggtc ttattttaat
    18061 ttttttagct atctatgtag atagcgtagg aggaaaacat gaataaacgc attaagaaaa
    18121 aacgtaaatt ggaaacagcg gttgtgatgc ttgttgcaga aaatgctatg caagctgaag
    18181 tactcaggaa tcaaaacaga caaattgcag agctgagatc gattatacaa caaaacgccc
    18241 aagcgacaaa tagagagttt gcagcagtta aatcagcgac gctagacaac caagcagcca
    18301 ttaagaaaat tggggatgag gtttattata tcaagcaaaa ttataagcgc aagtggcgga
    18361 aatagatgtt aatggtttag aaaggaggtg agaaatcgat gagttttttt caacctttgg
    18421 gcagttcaaa ggtgtcctat gatgactatg tatcatctgt tttagctggc gatgtctccc
    18481 aaaaatactt aggagtgtcg gctttgaaga atagcgatat tttaacagca acgtctatta
    18541 tagctgggga tattgctagg tttccgcttg ttaaaaagga tgttaatggg gacattatcc
    18601 atgatgagga tattaattat cttttaaatg ttaaatccac aaaaaatgcg agcgctagga
    18661 cctggaagtt tgctatggca gtaaatgcca ttttgactgg taattctttt tcgcgtattt
    18721 tgagagatcc aaagactaac caagctttgc aattccaatt ttacaggccg tcagaaacga
    18781 ctgttgagga gacagataac cacgagatag tttatacgtt tactgatatg ttgacagcaa
    18841 aacaggttaa atgttttgcc catgacgtta tccactggaa gttttttagt cacgatacaa
    18901 ttttgggaag gtccccgcta ctgtctttag gtgatgagat tgatttgcaa accggcggca
    18961 tcaatacctt aattaaattc ttcaaagatg gtttttctag tggcatctta aaaatgaaag
    19021 gcgcttatat aagcggtgaa gcacgtaaga gagccagagt tgaatttgaa aaaatgcgcg
    19081 agggtgcaat tggtggtagt cctttagtat tcgacgatac gcaagaatac acgccgcttg
    19141 aaatcgatac taacgtattg caattaatta caagtaacaa tttttcaacg gcgcaaatcg
    19201 caaaagcttt gcgggttccc agctacaagc ttggtgttaa tagtccaaat caatctgttg
    19261 cccagttgat ggaagattat gtcacgaatg atttgccatt ttattttgat gctatcacaa
    19321 gtgagttagg acttaagacg ctaagtgata aggataggcg tttgtatcgt atcgagtttg
    19381 atacacgaag cgtcacaggt cgcaatgttg atgagattgt caaattggtt aataaccaaa
    19441 tcttgacgcc taaccaaggc ctcgtagagc ttggtaagca aaaatcaaca gatccaaaca
    19501 tggataggta ccagtctagt ctaaactacg tctttttaga caaaaaagaa gaatatcaag
    19561 acaaggttgg tatcaaaggg aaaggaggtg aggtaaatgc caaagaggat aaatcttaaa
    19621 ggaccactaa ttgcaaataa ctctcaagaa gtttacgact attacggaat ggaagcagca
    19681 agtgctaaaa gtatcattga gcaatttcct gaagataata gcgatattgt tttggaagtt
    19741 aattcaaacg gtggacttgt gacagttggg agtgaaatct ataccgcttt acgaaattac
    19801 aaaggaaaag taactgcaga aattactggc atggctgcaa gtgcagcatc tgtggctgtt
    19861 atgggtgcgg ataaggttgt catgagtcct acagctcaaa tgatggtgca taaagcactc
    19921 tttaaatggg tgtctggtaa tagtgatgac ctagacaaag cttctaatgc cttaaaatca
    19981 agtgataaag ctattgtgag tgcctatgtc gcaaaaacag ggttatcaga agatgcaatc
    20041 atggatttaa tgcgaaatga aacgtttatg tccgctcaag atgccgtaga aaaaggtttt
    20101 gcggacgaag ttatgtcttt tgaagcagtt gctagcattg ataattccat gttgccgcaa
    20161 gctgttattg atgactatta cagaagtagg aacaaacgaa aacaagagat tagcaacatg
    20221 ttactagaaa ttgaaaaaga agaaatttta cgagggctat aagctctttt tttattggag
    20281 gaatttatgt tcgaagaaaa aatcaaagaa attaaagcga atatcgctaa tttaaaccaa
    20341 gctattgcta ctaaaacaac agaagtaaaa aatgctttgg aatcagatga ccttgaaact
    20401 gctcgctcaa ttaaagcaga aattgaagaa gctaaagcaa acctagcaga agcagaaaat
    20461 gacttgaaat tgtatgaagc tagcgttgaa aaaggcggtg cagaaaatac tggaggaaaa
    20521 gaagtgccac aagaaactaa aacatatcgc gaaagcgtta acgaatttat tcgttcaaaa
    20581 ggaacagtaa ccaacgaagg tttgcgtttt gaagggaaag acgaggttct tatcccactt
    20641 aaccaaacaa cgcctgtaga ccctaaaacg gatggtgtta agaaaacgga tgtaaaacct
    20701 gtctctagtg aagaaattct ttacacacca gcgcgtgaag tcaagacagt tgttgatttg
    20761 aaacaattca ctagcatcca cccagctaaa aaagaatcag ggaaatggcc agtattgcaa
    20821 cgtgctacag aaaaaatggt tagcgttgaa gaattggaaa aaaatccaaa actaggcaaa
    20881 ccacaattta aaaacgttga atgggaagtt aagacttatc gtggagctat cccactgtct
    20941 caagaatcta tcgatgatgc agatgtagat ttggttggta ttgttgctga aacaatcggt
    21001 caaatgaaag ttaatacaac taatgatgca attgctaaag tcctaaaaac atttgaggct
    21061 aaagctggtg tcaaaacatt agatgacatc aaaaaaatcc taaatgtaga tttagatcca
    21121 gcttacaatg tatcatttat tgtatctcaa agtttctatc aaaccctaga tactttaaaa
    21181 gacaaaaatg gtcgctactt gcttcaagac tcaatcacct ctgcgtctgg caaagtgttc
    21241 cttggaaaac cagtatttgt cctatctgat gacgtgattg gcgaagactc agcttttgtc
    21301 ggagatttta agcgaggcgt gttattcgct gatcgtaaag atttagggct tcgttgggca
    21361 gataacgaaa tttacggtca atacttgcaa gctgtccttc gctttggtgt cgctaaggta
    21421 gatgacaaag ctggatacta tgtgacattc aaaccagaac aattgccctc ataaggccac
    21481 tgaagaagtg gcgaaaccaa ctagcaaaag cactgtcgag gagattaagc gctatttaac
    21541 aagcaaggga attgacttta atgggaaaac attaaaatct gatttattaa aacttgcagg
    21601 cgttgaagag gtatagctat ggctgtatca aaagagttat tagacagtgt aaaactctat
    21661 tgtaaaattg actttgattt tgatgacgac atcatcaaag aaatgattga atctgctcaa
    21721 gaacaaatct gttttgcaat agaagacggt tctactcctg aaaagttcaa aggtcacgct
    21781 aaatttaatt tagctgtcaa aaagcaagtc aaggaagagt atgaccatcg cggtttgtct
    21841 gcggatagtt ttcgctatcc gttggcaaat ggtgttttaa acattatcca tcaattgcga
    21901 ttgagaggtg atgattcgtg attacacgca agatgaacgt caggataacg atttttagcc
    21961 aatcaggcgg gcaaaatgaa gatggtgaag tagtatctgc tgtcagaaag gacttgtata
    22021 cttgttgggc agaagtgcta aaaacgcagt tgagagattt taattatcaa tcaaagtatc
    22081 aaaacgctag caatttgcca acaaataagg atactaaggt ttttttaatt aggtataacc
    22141 ctgaattatc tatagataac acgatgtttg ttgagtttgg caagcgcatt tataagatag
    22201 ataaaatcga atctgacgaa tctggcaaag atattatcat gataagtgga gtaagcatgt
    22261 catgacaaaa ggtttagatg aaatattggc taatctgaca aagcttgaag taaaagcacc
    22321 aaaaaccgca aaagcagcag taactgaagt tgccaaagaa tttgaaaaag cacttaaagc
    22381 aaatacccct gtttatgaga ttgaaacaga tgagcggcta caggaagata ccgttatcag
    22441 tggttttaaa ggagctaatg ttggaattgt atccaaggaa atcggctatg gcaaagcgac
    22501 tggttggcgt gcgcactatc ctaacgatgg gaccatttac caacgcggac aagactttaa
    22561 ggaaaaaact atcaatcaga tgacaccaaa agctaaacaa atctacgcag caaaagttaa
    22621 ggagggacta gggctttgat tgctgaaaca gcagcttata aattattaag taacgataag
    22681 acgctaaatg agttgttgga taggctcaga ggcggtcctt ttaaaaatgg gtttaagcaa
    22741 ggcatattta cttatgatat tccagataac ccagttgact tgcgtaaggt agatttagcg
    22801 ccttttatgc gaatcaacac aacattagac ggtcctgctg attatgcaga tgatgagata
    22861 ctgtgtaacg agcaacggat caccatcaat ttttggtgca aaacagcttc tgaagctgac
    22921 caaattagca aatgtataga tgatatttta aaaaaaggcg gttttgaaag atacaccgca
    22981 aacgaaaaac caagatataa agatagcgat attgacttac tcatgaacgt aaggaaatac
    23041 cgctattttg atttttattt aaaagaaaga ggaaaaaatg ggaaaagtaa aatttggact
    23101 acgtgatttt cagtacgccg tactaggcga agatgataat gttgcaacga aaaaaggtgg
    23161 tattaaaaaa ctacctggaa tgaaatctgc aaaactcgat attaccaatg aattggttac
    23221 cgtttcggca gatgatgggc cttatgtagt gctttcggga ggaatcaccg aaacaaaact
    23281 agaaattgaa gtactcgatc ttacaaccga tgcacgtaag gactttttcg gcattaaagt
    23341 ggcggcaggt gttgaaaaat ataacaaaaa cttgacacct aataatgtag cctgcatttt
    23401 tagaacaagt gatgagaacg ggaaggctat ttgggtagga ctgcttaaag gtaaatttaa
    23461 tttacctggc atggaaactc aaacaaaaga aggatctcct aaccccaaag ctgataccgt
    23521 aacaggtaac tttgtgtctc gtggcaccga tggagacgtg cttgttattg gaagagaaga
    23581 aagtcatgaa tttaattatg aagcttttgc aggatttgtt tttgctggtg cgacagatat
    23641 taaaaaaggc gaaaacttcg aaatgtaaca atcaggttgg attttaaatc caacctttta
    23701 tttttgataa ggagtagata tgtacgaaat taccttaaaa aaaggtggtg tagataaagt
    23761 tttttcaaaa gactttatta acgttgagga taatttgttg gctgttgagc atcaagttag
    23821 acaaagcgct gtgtttagcg atgagaaaag acgcttagat tctaaagcgc atagaaaact
    23881 taacgaatct tacttgcaaa tgtttgttga tatgtacgca ggtcaattta cagtcgatga
    23941 tttaaagcaa tctgacatga gtgttttaaa tacacttaat gacctgtaca ttgcagcact
    24001 cggtggagag caagaggaag acgaaagcga aaaaaaggaa caataacccc acaagaggct
    24061 aaagaaaact tactcttgtg gatacagagc cttttgaaaa acggttatac cattttagat
    24121 attaaaaaaa tgcgcttatc tgatattgaa ttgatggtac aagcgctaga aattgaaact
    24181 gtcgaaaaag aagaagtgat tgaaacgacc ttggataagg cattcccatt ccttttcggc
    24241 tagaaaggag gctaaatggg gaatataggt gatttagtag caacggctac actagacata
    24301 tcaccattta tgtcaaacac aagaaaccta aaaacctaca tgaaaggctt agacaactcg
    24361 ttaaaagctg ttgaaaagag ttttcaaggg catggcgggc ggattaaagg tcttaaagcg
    24421 gtctatgctg aaacaggtag tgcattaaaa ggttaccaag aattactaaa aactcagtca
    24481 caaaaatata gcgacctaaa aaaagagata ggcgatgtta ataacgctac tgctgagcaa
    24541 aagcaaaaat tgattggcgc taaatcagcc atgttggaga ctgctgcgaa agtcacagaa
    24601 ttgcaaaaca gattacgagc gttagccact gaaactagcg tttttacaag atttggtaaa
    24661 gctgctgaaa aaatcggcgg caagatgaaa tcattaggtg attctgtagc aggagttggt
    24721 gctgcattta cgagaggagt taccgctcct attgtagcgg gcgctggtta tgctattaaa
    24781 gcagctgttg actatgaaac tgcgtttgcc ggtgttaaaa aaacagttga tgagacggcg
    24841 acagtatcct atgctaagtt gtcgcaaggc attaggcaaa tggctaaaga gttgccagcc
    24901 agcgcggtag aaatcgctca cgttgcagag gcggcaggtc aattagggat taaaacaggt
    24961 gatatcctta gtttttctcg tacaatgatt gatttaggag aatccactaa tctatccgca
    25021 gaagaagctg catcatctat tgcgaaaatc gcaaacatta caggactaac gtcaaaggaa
    25081 tattctagat ttggtagctc tgttgttgcc ttaggtaata actttgcgac aactgaaaga
    25141 gatattgttg cgatgacaaa ccgtatcgcc gcatctggta aacttgccgg cttaactaat
    25201 caagaaatgt tagcgttggc aactgctatg tcaagcgtcg gtatcgaggc agaagctggt
    25261 ggtactgcta tgactcaaac attatcagca attgaaactg ctgttattaa tggtggagaa
    25321 gatttaacaa aatttgctca aattgccaat atgtcatccg ctgattttgc aagagcgtgg
    25381 aaagagaagc caattgttgc attgcaagag tttattaagg ggcttggtca acttgataaa
    25441 aaaggtgaaa gtgctacaaa agtgcttgat gaactcggtt taagtggtat ccgccagtct
    25501 aacatgttga aatctttagg attagcatct gagactttag gcaaggctct tggaatctct
    25561 aacaaagctt ggcaagaaaa cactgcttta actgacgaag ctaataagcg ctatgagaca
    25621 acagagtcta agctaaaaat gcttaagaat gaagttaatg atgtagctat tgaatttggt
    25681 ggccctttgg ttgacgctct aagaaatggg ctcgaagcag gaaaaccaat tattcaaatg
    25741 gcagcagatt tagccaagca atttaactcg cttgacaaag agcaacaaca gcagattatc
    25801 aagtggggac ttattgctgc cgccgctggt ccagctttgt ctatctttgg taaaggtgtt
    25861 ggcattattg gcagtactat tcaaggcatt gggaaaatga gtcaaggttt aggagcgttg
    25921 tcaggctggt tgcgcacttt taaaactgga gcggcagcag ctagtgcagg agccgaagct
    25981 gccacagctt ctatgggcgg aatggctggc gcggttgcct tattaagcaa cccagtaacg
    26041 tggggtgttt tgctaggtgg ggcagccatt gtgggtatag gtttaattgc tgatagcatg
    26101 tataaagccc aaaaacgcac agaagagtgg ggaaccgctg tttccgcgac agaagcaaat
    26161 gcactaagta actttaagaa aaaagttgac gaaactaaca cttcgttgca aatgttcgag
    26221 gcaggcgcag gtagcgttaa gaaagtgact gaagcttttg atgatttggt cggaagtatt
    26281 gaaaagttag ctcaatcaaa attagataag aatataaact tagctaaaaa attaggatta
    26341 tcagaagaaa ccataaatgc tttgaaatcc aaaactgaat cagtggttaa caatgttaaa
    26401 agcatgaata cccagattaa agcaatcatg gagaaacaca acggtgacat gagccagttg
    26461 tcaagcgctg aaaaagaact tgttttgcga aatcaaagag aaatgattac cgctcaactt
    26521 gatttaatga agttctctgc atcagaaaag aaagctttaa cagcagcttt gaataacgaa
    26581 ttagatgccc tcaacgcaag acagttggaa aaagtatccg aaaacaccgt taagatgctt
    26641 gataaagaaa attctgctta caaaacaaaa aaagcagaat taaaagaaat tttaaagcaa
    26701 tttggaagcg atactagcaa gctaagcgct gaagaattgg ctgctagaca ggaagttttg
    26761 aatagactta ctgagttaaa tatgcagcac aacctaaaaa ccaaagcttt gaacgatcag
    26821 taccttgcta tccagaggga gcgtgtccaa cggttaaaag aatctggcaa gagtcaagaa
    26881 gaaatccacc aagggattag ccaaatggca tcagacatgg ctcagaagct tggtattagc
    26941 tatgacgatg cttaccgtaa actagcttat tatactgaga aatctggtga aacgttgaaa
    27001 gttttgtcgc gtaatacggc taatgctacg gcggaagtag cagcagctaa cgctcagtgg
    27061 gatagcttgt ttacgagcga taatccacaa caaagcctaa acgaattgtt atcgaccgca
    27121 gaaggctgga acagttttga aatcatggtt aagaatgccg acgttgaacc gacaggtaga
    27181 gccgcacttg ctgaaatgtt ggtagctggt ggccaatggg aaaacatgac gttagagcag
    27241 aagaagttgg ttgttgatgg tcaacaagcg atgattgaaa tctttgatag caaggagtta
    27301 ttagcgcagt ggcaagcatt gacgccagaa gaaaaggttt tgctagcgaa aaacttaaca
    27361 caagaaccaa ctatgtcggc tcaacaagcc cttgacagtg tcaagcaaac agtacctgct
    27421 gatgttaacg caagtgataa aacagcaggc gaaactcaat cagcacaaaa caagattgac
    27481 aatgttaaac aacgagttcc agctgatgtg aaagcatcgg ataagactgg accagatgta
    27541 gcaagtgctg acagggctgt caatagtcct aaacaaaaaa gtccagctgt tatcagagcc
    27601 caagataatg ctagcggtgt tgcagaaggt gttataggtg cattggctag aatcccaaga
    27661 agtgttacaa caaccattac aacgtttgtc cgtaagattt ttggacatga aaaagggact
    27721 gatttccacc ccggcgggtt agctatggtc aatgaccaaa aagggccgct atacaaggag
    27781 ttggtcactt taccaacggg tgaatcattt attccaagcg gacgaaatgt catcctccct
    27841 ttgccaaggg ggtctaaagt cttaaaggcc agccgtacaa aacaattatt cccgcactat
    27901 gccagcggaa taggttttga tgacaccaaa atcgctagtc tgacaactcg tcttaaatct
    27961 gtgcaagata aggggcaagt gattatcaat accgaccctc aacttgcgga gttaattaaa
    28021 ctacttaaag acagagatga cagaaatgtc acaaataact ataccgtaaa cgctactaat
    28081 agtagtagtt cagaggatat gtttagccaa gaaaatatga gacggctact cagagaatta
    28141 gcttactaca cgaacggaga aggagggagg ttagcttaat gcgatacatt gaatttaatg
    28201 gcactaaaag caatgattta ggtttattgc tagagcgcga acgatcaatt aagtcaacaa
    28261 acaacgacat tgatttaatc gaagtagcag gtcgtgacgg tgtacttatt aaagacaacg
    28321 aacgcttaaa agcggttgag caagactttc ctttttcgct ggttggtgac gtgactgtca
    28381 atcaacaaaa aataagcgaa tggttacatg tcaagggttg gcacgacttg gcgttgtctt
    28441 gggacaagga ttatatctat cgggctagtg ttgtcaatct ttttgaaata gacgagatac
    28501 ttaagcaatt tggtagatta aaagttaatt tcttaatcca ccctatcaaa tatttaaaaa
    28561 caggtaagca agaggtgcct ctcgtaaatg gaggtactct acaaaatcct ggcaatgtcc
    28621 aagctaaacc tatcttaaaa atcaaaggca caggcaatgg tgttttaacc attaatgact
    28681 ttgagacagg acttgaaaat gtacagggcg agcttgttat agatatggaa aggcatcttg
    28741 tctataagga tgttttatcg gcttgggata atatcgtaag gacagaacat catcgcatgc
    28801 ctctttttga tattggtcaa aacaaaatct catggactgg taactttact atcaccgcag
    28861 tgccaaactg gggggttaaa gtatgatacc agttttatac gaggccaaag aaaccaaatt
    28921 taggactttt ggccttggag aaattgcgga cgcttacgag gttaaagcta cacgtgagcg
    28981 taatggcaat tactcgttat atatcaaata tcctttagat ggtgcctttg ctcatctgtt
    29041 caaagaagag atgaagatta agtccgatgc tgggcgtagg actaagtggc agacgtttga
    29101 gattaatcgg gtgctgcgga atagtaaaga gcacattgag atttttgcac gccacatatc
    29161 gatgcgcaca caggacatcg ctttaaaacc atttgtgagc gggtctagca ttgacgcaga
    29221 gtcggcactg gaggtttggc gggataatct tgtcggtgat gatacctttg atgttaaaag
    29281 cgacatttta acactaggca gctttaactg ggaagttgac aagataggca atgcaagagg
    29341 cgctctcggg ggtgtcgctg gctctatctt agatgtttac ggtggtgagt acgagtttga
    29401 caatcgcaca atcatcttac ataaacaaat ggggcgtaag acccctacgg ttttggagta
    29461 tggccgcaat atcgttagcg tggaagagga gcgtttgctt gatggcaatt atacctcaat
    29521 ctatccttac gtaagatata cgccacaacc aaagccgcaa gaggaagcct ctggtaagcc
    29581 gcacatcggc gagcatgaga aacccgaaga acagctggtc actttgcctg aatttatcat
    29641 agacggtcag tatcttgact tatatgccca acgcagaata cagatggttg atttatctag
    29701 tcattttaat gatgacaaaa aagagccaac agtcgaagaa attagaaagc tggctcagaa
    29761 ataccttaaa gataataatg taggcgcacc taaaatcagt atagaggttg attatatcga
    29821 cctgtcacag acgcttgact atcaagattt tagagttatg gaggaggtcg agctttgcga
    29881 tattgtaccg ctttactatc caaagtttgg tatcacaacc gagaccgaaa aagtcgttga
    29941 gattgtctat gacgtctata cagatagcaa tcacacaata aagcttggca cgattggcca
    30001 atccatctct aagagtctga caggtggtgt tacgcagcgg attgagacgc tggaaaacaa
    30061 ccaaaaggtt attactaata atcaacagca atttgagctt aatttaccca aatacctcaa
    30121 cgatctaaac ggtaccaaga tatggtacga aaaaccagat gacaacgttg agcacaagat
    30181 aggcgatttt tggtttgaga aaaacggtaa atatcagcgt acctgggttt gggacgggaa
    30241 tcaatgggta aaaatcattg atactgagga tttaaatcct aatcagcgcg cttttgatga
    30301 ggctatggcc gagatcgaaa agcttaagca gcaccaacaa caaattgaca aacgcaatca
    30361 gcgggagctt gaagagttta gagacaccct caaaaaccta gcgttaccag aggaagcgat
    30421 caaaaaaatc actgaggcta tcaaagttga tgacatcccg tcaattaaac agtcgtttga
    30481 tgacttaaaa aataaagtca gcgagacaag cgagaccgca cgattaaacg ctgagattat
    30541 cgggacagat ggtaagaccc gctataacaa aaatctcttg gttggcgacc c
//
LOCUS       DARYYD010000026        27475 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.026, whole genome shotgun sequence.
ACCESSION   DARYYD010000026 DARYYD010000000
VERSION     DARYYD010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 27475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27475
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.026"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            140..406
                     /locus_tag="TV188_001076"
     CDS             140..406
                     /locus_tag="TV188_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003067640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEL1534442.1"
                     /translation="MKAIITVVGKDNQGIVAGVSGQIAALGLNIDDISQTVLDDYFTM
                     MAIVSSSEKQDFAHLREVLQAYGKQLQVTINIQSAAIFDAMHNI"
     gene            421..1758
                     /locus_tag="TV188_001077"
     CDS             421..1758
                     /locus_tag="TV188_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEL1534443.1"
                     /translation="MDIRQVRETVEMIEEQHFDIRTITMGISLLDCIDSDIDRAAAKI
                     YQKITTKAANLVAVGDDIAAELGIPIVNKRVSVTPIALIGAATDAEDYLSLAKALDQA
                     ACDIGVDFIGGFSALVQKGYQKGDKILIESIPQALAQTQKVCASVNVGSTRSGINMTA
                     VADMGRIIKETAKASEIGAAKLVVFANAVEDNPFMAGAFHGVGEADTVINVGVSGPGV
                     VKRALEKVRGESFDVLAETVKKTAFKITRIGQLVGQMASERLGVGFGVVDLSLAPTPA
                     VGDSVARVLEEMGLEIVGTHGTTAALALLNDAVKKGGVMACNRVGGLSGAFIPVSEDE
                     GMIAAVQGGSLNLEKLEAMTAICSVGLDMIAIPEETPSETIAAMIADEAAIGVINQKT
                     TAVRIIPKGKEGDMIAFGGLLGTAPVMAVNPHSSADFIARGGQIPAPIHSFKN"
     gene            1833..2540
                     /locus_tag="TV188_001078"
     CDS             1833..2540
                     /locus_tag="TV188_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1534444.1"
                     /translation="MTKTRLYIVRHGKTMFNTIGRAQGWSDTPLTKAGEEGIRELGLG
                     LKAAGIPFKAAFSSDSGRTMQTMEIILRKSENEFLPYTRDKRIREWCFGSLDGAYDSE
                     LFLGVLPRTKAFENRDNLRDVPYSELAESIVEVDTANWAEPWEVLSKRIYEGFEAIAL
                     AVENAGGGNAIVVSHGMTIGTFMWLIDPDREKQYIDNGSVTVVEYENGQFTIKTIGDM
                     SYRYRGREIIESIRDEE"
     gene            2530..3273
                     /locus_tag="TV188_001079"
     CDS             2530..3273
                     /locus_tag="TV188_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="HEL1534445.1"
                     /translation="MKNNTIRVLLQALVVLLFLSGVYLFIKPEKQAVGPKANQTVPAP
                     KAAKQAKKTTDLPKVSTTDWQLVLVNRDHPQEEMSPELVEINGIPIDKRIEQETADFL
                     AAAQTIEPQEHLIAGYRSVVQQEELYQSYIAQELANDPSLTQEAAEALVRKYAQPAGT
                     SEHQTGLAIDMSTVDNLNASDPKVAQEIQKIAPQFGFILRYPKGKQTSTGIEYEDWHY
                     RYVGKASALYITAHSLSLEEYLTRLKEKK"
     gene            3270..3842
                     /locus_tag="TV188_001080"
     CDS             3270..3842
                     /locus_tag="TV188_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1534446.1"
                     /translation="MRKRLKFSYFLVFLVFIMVALIGPLLFNAKGTSASQEMSVPYTE
                     RQFIQLVAKEVKPLAKNYGIRPSILIGQIILETNYGRTLLAAKYHNLFSLQPAPGQAS
                     ISLKKQAASKHKTAYAIYRDREDSIRAYLSWLSQGTGEEKKLYQSLATEKGYKKPAKS
                     LQTYRYSDDKGYAQRLVQLIEARGLTSYDD"
     gene            4292..5326
                     /gene="hrcA"
                     /locus_tag="TV188_001081"
     CDS             4292..5326
                     /gene="hrcA"
                     /locus_tag="TV188_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEL1534447.1"
                     /translation="MITERQSNILNLIVDLFTQTHEPVGSKALQSLIASSSATIRNDM
                     AKLEKLGLLEKAHTSSGRMPSAAGFKYFVEHSLNLGSIDEQDLYQLVKAFDFEAFKLE
                     DVLLRASQMLSDTTGYTAAILDVEPARQRLTGFDIVQLSSHDALAVLSLDESKPLTVQ
                     FAIPKNFMNRDLLVLKGIVADRLLGKDVMTVHYKLRTEIPQIVQKYFTVTDNVLDLFD
                     YIFVGLFRETIFVSGKVAALDYAGLATYQFLDEEQRLALSIRQSLSEEEMATVQVADS
                     SEPALANVTLLTYKFLIPYRGFGLLSLIGPVDMDYRRSVSLINVIGQLLAVKLRDYYR
                     YLNSNHYEVH"
     gene            5371..5940
                     /gene="grpE"
                     /locus_tag="TV188_001082"
     CDS             5371..5940
                     /gene="grpE"
                     /locus_tag="TV188_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEL1534448.1"
                     /translation="MSKKPKEELKDQEDILDEAAEEAVEPVEEADQSAELIADEAAEE
                     PSELELALQRAEDFENKYLRAHAEMQNIQRRANEERQSLQRYRSQDLAKKILPSLDNL
                     ERALAVEGLTDDVKKGLEMVQESLVQALKEEGIEEVPVEAFDHNLHMAVQTLPADDDH
                     PADSIAQVFQKGYKLHERLLRPAMVVVYN"
     gene            6345..8174
                     /gene="dnaK"
                     /locus_tag="TV188_001083"
     CDS             6345..8174
                     /gene="dnaK"
                     /locus_tag="TV188_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEL1534449.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVAANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLATAGDNKLGGDDFDQKIIDFLVAEFKKEN
                     GIDLSQDKMALQRLKDAAEKAKKDLSGVTQTQISLPFITAGAAGPLHLEMSLSRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQHIVIKSNDGLSEEEIERMMKDAEANAEADAKRKEEVDLKNE
                     VDQAIFATEKTIKETEGKGFDTERDAAQTALDELKKAQESGDLDDMKAKLEALNEKAQ
                     ALAVKMYEQAAAAQQAQAGAEGAADTGSTNSGDDVVDGEFTEK"
     gene            8331..9467
                     /gene="dnaJ"
                     /locus_tag="TV188_001084"
     CDS             8331..9467
                     /gene="dnaJ"
                     /locus_tag="TV188_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015911812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEL1534450.1"
                     /translation="MNNTEYYDRLGVSKDASADDIKRAYRKMSKKYHPDINKEPGAEQ
                     KYKDVQEAYETLSDSQKRAAYDQYGAAGANGGFGGGAGGFGGFDGGGFGGFEDIFSSF
                     FGGGGMRNPNAPRQGDDLQYRVNLSFEEAVFGTEKEVSYHRESTCSTCAGSGAKPGTS
                     PTTCRKCHGSGVINVDTQTPLGMMRRQVTCDVCHGSGQEIKEPCHTCHGTGHEKKVHK
                     VSVKIPAGVETGQQIRLQGQGEAGFNGGPYGDLFVILNVLPSKQFERNGSTIYYSLNI
                     SFVQAALGDTVDIPTVHGDVAMSIPAGTQTGKVFRLKGKGAPKLRGGGQGDQHVTVNI
                     VTPTKLNEAQKEALKAFAEASGEKPIAPKKKGFFDKVKDALEDI"
     gene            9787..10578
                     /locus_tag="TV188_001085"
     CDS             9787..10578
                     /locus_tag="TV188_001085"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEL1534451.1"
                     /translation="MTFQNIIFELEEDLAILTLNRPEVSNGFNIPACQEILEAIRLVK
                     DNPSLRFLVIKAKGKVFSVGGDLVEMQNAVERDDVQSLVRIAELVQDISFAIKQLPKP
                     VILCADGAVAGAAFNIALAVDFCIASTQTKFIQAFVNVGLAPDAGGLFLLTRAVGLNR
                     ATHLVMTGEGVTAEKGLEYGFVYRAAESDKLDKTCSQLLKRLRRGSSNSYAGMKSLVW
                     QSFFAGWEDYAQKELAIQEELAFKEDFKEGVRAYGDRRRPNFRGK"
     gene            10658..11092
                     /locus_tag="TV188_001086"
     CDS             10658..11092
                     /locus_tag="TV188_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1534452.1"
                     /translation="MEYNKINQYLVDIFNRILVIEEMSLKTSQFNDVSLKEMHTIEII
                     GKYQQVTPSDIARELMVTLGTVTTSLNKLELKGYIERTRSSVDRRVVYLSLTKKGRLL
                     DRLHARFHKNMVGHVIADMNEDEMQALLRGLGNLHQFLEDLV"
     gene            11092..12066
                     /locus_tag="TV188_001087"
     CDS             11092..12066
                     /locus_tag="TV188_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEL1534453.1"
                     /translation="MVFSKISQVAHYTPKQVISNDDLSQIMDTSHEWISSRTGIEKRH
                     ISTVEMTSDLAIRVAEQLLAGSGYDATALDFIIVATISPDASMPSTAAKVQAAIGATN
                     AFAFDMTAACSGFVFALAMADKLIASGAYQRGLVIGAETLSKIIDWQDRSTAVLFGDG
                     AGGVLLEASEQQHFLAEALHTDGAQGQSLTSGQSSLRSPFSQGQEVNSFLQMDGRAIF
                     DFAIRDVSRSITAIIEQSGLAKEELDYLLLHQANRRILDKMAKKIGMPREKFLENMMH
                     YGNTSAASIPILLSESVQNGQLKLDGSQHILLSGFGGGLTWGSLIVKI"
     gene            12124..12348
                     /locus_tag="TV188_001088"
     CDS             12124..12348
                     /locus_tag="TV188_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002938891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1534454.1"
                     /translation="MAVFEKVQEIIVEELGKDAEEVTLETTFDDLDADSLDVFQVISE
                     IEDAFDIQIETEEGLNTVGDLVAYVEEKTK"
     gene            12543..13529
                     /gene="fabK"
                     /locus_tag="TV188_001089"
     CDS             12543..13529
                     /gene="fabK"
                     /locus_tag="TV188_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEL1534455.1"
                     /translation="MKTRITELLNIDYPIFQGGMAWVADGDLAGAVSNAGGLGIIGGG
                     NAPKEVVKANIDRVKAITDKPFGVNIMLLSPFADDIVDLVIEEGVKVVTTGAGNPGKY
                     MERLHEAGIIVIPVVPSVALAKRMEKLGVDAVIAEGMEAGGHIGKLTTMTLVRQVVDA
                     VSIPVIAAGGIADGRGAAAAFMLGAEAVQVGTRFVVAKESNAHQSFKDKILKAKDIDT
                     VISAQVVGHPVRSIKNKLTSAYAKAEKEFLADRKAASDIEEMGAGALRNAVIDGDVIN
                     GSVMAGQIAGLIRAEESCEAILKDIYYGAAAVISQEAKRWQALAADDKNETI"
     gene            13542..14462
                     /gene="fabD"
                     /locus_tag="TV188_001090"
     CDS             13542..14462
                     /gene="fabD"
                     /locus_tag="TV188_001090"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEL1534456.1"
                     /translation="MTKTAFLFAGQGAQTLGMTRDLYDQYAIARDTFDQASQLLGYDL
                     RKLIDTDQDRLNQTAYTQPAILTASVSIYRILTSYGVHPDMVAGLSLGEYSALVAAGV
                     LSFETALELVAKRGRFMEEAAPAGSGKMVAVMNTEARLIEEACQEASSVGVVSPANYN
                     TPGQIVIGGTAEAVNAALEILKAKGVKRLIPLNVSGPFHTALLAPASQRLAEELSKIQ
                     FQDFDLPLVGNTEAKVMEKDRIAELLARQVMEPVRFYDSIEVMKANGITQFVEIGPGR
                     VLTGFIKKIDKKLLCSSVEDMPSLQLYLGK"
     gene            14479..15213
                     /gene="fabG"
                     /locus_tag="TV188_001091"
     CDS             14479..15213
                     /gene="fabG"
                     /locus_tag="TV188_001091"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEL1534457.1"
                     /translation="MEIKGKNVFITGSTRGIGLAMAHQFAGLGANIVLNGRSAISDEL
                     VETFKDYGVKVVPISGDVSEGADAKRMVDEAIEQLGSVDILINNAGITNDKLMLKMSE
                     EDFERVLKINLTGAFNMTQSVLKPMTKARQGAIINVSSVVGLTGNIGQANYAASKAGL
                     IGFTKSVAREVAARGIRVNAIAPGFIESDMTGVLSEKMQEQILNQIPMKRIGKGQEVA
                     QAASFLASQDYITGQVLAIDGGMTMQ"
     gene            15229..16461
                     /gene="fabF"
                     /locus_tag="TV188_001092"
     CDS             15229..16461
                     /gene="fabF"
                     /locus_tag="TV188_001092"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEL1534458.1"
                     /translation="MTLNRVVVTGYGVTSPIGHTPEEFWSSLKAGHIGIKPITKFDTS
                     DFAVKNAAEIQDFPFDKYFVKKDLNRFDMYSLYALYAATEAIEHAGLDIEAIDSDRFG
                     VIVASGIGGIQEIEEQVIRLHEKGPKRVKPMTLPKALPNMAAGNVAMKLNAQGVCKSI
                     NTACASSNDAIGDAFRTIKFGLQDVMMVGGSEAAITKFAIAGFQSLTALSTTEDPSRS
                     SIPFDKDRNGFIMGEGSGMLVLESLEHAQKRGATILAEIVGYGNTCDAYHMTSPHPEG
                     LGARKAINLALQEAGIDAAAIDYVNAHGTSTPANEKGESQAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIATIEAIRHNYVPMTAGTKELSDDIEANVIFGQGKEADIRYAMSN
                     TFGFGGHNAVLAFKRWED"
     gene            16463..16936
                     /locus_tag="TV188_001093"
     CDS             16463..16936
                     /locus_tag="TV188_001093"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEL1534459.1"
                     /translation="MNIQEIKDLMAQFDASSLREFSFKSSDGELLFSKNEHRPMAAPA
                     PEPVTLHQEVAPISLTQEIVSKQESIPASSGLQEPEGEVVDSPLVGVAYLAAGPDKPP
                     FVTVGDSVKKGQTLLIVEAMKVMNEIPAPCDGIVTEILVANEDVVEFGQGLVRIK"
     gene            16933..17355
                     /gene="fabZ"
                     /locus_tag="TV188_001094"
     CDS             16933..17355
                     /gene="fabZ"
                     /locus_tag="TV188_001094"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEL1534460.1"
                     /translation="MMDIKQIQEALPHRYPMLLVDRILEASDDEIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKEENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTARFIKRRGTIAVVEAKAEVDGKLAASGTLTFAFGQ"
     gene            17389..18753
                     /gene="accC"
                     /locus_tag="TV188_001095"
     CDS             17389..18753
                     /gene="accC"
                     /locus_tag="TV188_001095"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEL1534461.1"
                     /translation="MFNKILIANRGEIAVRIIRAARELGISTVAVYSEADREALHTIL
                     ADQAICIGPSRSKESYLNMNSVLSAAVVTGAQAIHPGFGFLSENSKFVTMCEEMNIKF
                     IGPSGAVMDKMGDKINARAEMIKAGVPVIPGSDGEVYNAQEALEIARQIGYPVMLKAA
                     AGGGGKGIRKVESEADLEAAFNAASQEALGAFGNGAMYLEKVIYPARHIEVQILGDSQ
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGTTLRQRMGEAAVRAAKAVSYENAGTIEF
                     LLDEASGDFYFMEMNTRVQVEHPVTEFVTGVDIVKEQLRIAAGLPLSVRQEDIVITGH
                     AIECRINAENPSFNFAPSPGKITDLYLPSGGVGLRIDSAVYSGYTIPPYYDSMIAKII
                     VHGDNRFDALMKMQRALFELEIEGIMTNIDFQMDLISDKQVIAGDYDTSFLMETFLPS
                     YNKD"
     gene            18762..19628
                     /locus_tag="TV188_001096"
     CDS             18762..19628
                     /locus_tag="TV188_001096"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEL1534462.1"
                     /translation="MALFSKKDKYIRITPNNSLKSSVSRNVPEVPDELFAKCPACKHM
                     IYQKDLGPAKICPTCSYNFRISAQERLTLTVDEGSFQELFTDIETKDPLRFPDYQAKL
                     QKARQATGLHEAVLTGTALVKGQRLALAIMDSHFIMASMGTVVGEKITRLFELAISER
                     LPVVIFTASGGARMQEGIMSLMQMAKVSAAIKKHSNAGLFYLTILTDPTTGGVTASFA
                     MEGDMIIAEPQSLVGFAGRRVIETTVRENLPDDFQKAEFLKEHGFVDAIVKRTDLRDR
                     IAHLVAFHGGVS"
     gene            19625..20395
                     /locus_tag="TV188_001097"
     CDS             19625..20395
                     /locus_tag="TV188_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEL1534463.1"
                     /translation="MTDVARILKEARDQGRMTALDYASLIFDEFMELHGDRQFADDGS
                     IVGGIAYLADQPVTVIGIQKGKNLQDNLARNFGQPHPEGYRKALRLMKQAEKFGRPVI
                     TFINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADQ
                     VWMLENTMYAVLSPEGFASILWKDGSRATEAAELMKITAAELYQMGVIDRIIPERGYF
                     SSEIVEMIKSHLIDEITQLQAKPLEELLDQRYQRFRKY"
     gene            complement(20627..21904)
                     /gene="serS"
                     /locus_tag="TV188_001098"
     CDS             complement(20627..21904)
                     /gene="serS"
                     /locus_tag="TV188_001098"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEL1534464.1"
                     /translation="MLDLKRIRTDFDTVAAKLKTRGVSEAILTSLKALDEQRRTLLVQ
                     TEELKAQRNIASAAIAQAKRQKEDASQQIADMQQLAANIKAIDAKLADIDQEITGIIT
                     VLPNTPHDSVPIGADEEDNVEIHRWGKPRQFDFDIKAHWDLGEALDILDWERGAKVTG
                     ARFLFYKNLGARLERALYNFMLDEHLKEGYQEIIPPYMVNHDSMFGTGQYPKFKEDTF
                     ELDGTNFVLIPTAEVPLTNYYRGDIIDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPETSYEELEKMTANAEHILQKLKLPYRVLALCTGDMGFSAAKTY
                     DLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEVLRPYMGGLEVIKPR"
     gene            22504..23556
                     /locus_tag="TV188_001099"
     CDS             22504..23556
                     /locus_tag="TV188_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HEL1534465.1"
                     /translation="MTLDKNRHYGLDLLRIISMFMIVITHVLGKGGLRSTVEGEADSY
                     FIVTWMIQVLVYGAVNCYALISGYVGIKSPYKYSKIVNIWVQVFFYSFLMTLLFALFG
                     FPVSLENWRQALFPIVSGNYWYITAYFGLLIFMPMINGGLNTLSNKQLGRLVLLVFAI
                     FSLIPALMNQQVDEFSLSKGFEMTWLIILYIIGAYLRRIELSRFSHKLLIAVYMGSLV
                     VTYIMKFMVGNIWYWYVSPSLTLGAIALFILFAKLKLTSETLLLRFIVIVSPTTLGIY
                     LVHLHPLLVKFIIRDFAEPFVNAPILLYPLLIFGVGIVIYFLSFLVEQARLMLFKKLG
                     FQNLLKWVDKKIPFAD"
     gene            complement(23877..24260)
                     /locus_tag="TV188_001100"
     CDS             complement(23877..24260)
                     /locus_tag="TV188_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEL1534466.1"
                     /translation="MAQSLNQRVILQTTAVSYLGIGGKVGKILLGDKALEFYNDKNVE
                     DFIQIPWTAINQIGANVSGKKVSRHFEIFTDQGKFLFASKDSGKILKVARETIGNDKV
                     IKLPTLVQTIIAKLFHHQKKDKKSH"
     gene            complement(24394..25305)
                     /locus_tag="TV188_001101"
     CDS             complement(24394..25305)
                     /locus_tag="TV188_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1534467.1"
                     /translation="MTEQIKLTKADRKRVWWRSQFLQGSWNYERMQNMGWAYALIPAL
                     KKLYTTKEDRAAALERHMEFFNTHPYVAAPIIGVTLALEEERANGTAIDNAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGALGASLAQTGNLVGPLLFFFGWNIIRMAFLWYTQE
                     FGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVSINFTINLPGKQLSEGA
                     YVVFPEGAVKGAELKSILGQAMGGMSLDKVQSQTLQGQLDSLIPGLAGLLLTFLCMWL
                     LKKKVSPIAIIIALFAFGIIAHLLHIM"
     gene            complement(25321..26130)
                     /locus_tag="TV188_001102"
     CDS             complement(25321..26130)
                     /locus_tag="TV188_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEL1534468.1"
                     /translation="MSDISLISAILVVIVAFFAGLEGILDQFQMHQPLVACTLIGLVT
                     GHLEAGVMLGGTLQMLALGWANIGAAVAPDAALASVAAAIIMVKGGDFTQKGITFAYS
                     TAIPLAVAGLFLTMIVRTISTVLVHAGDKAALEGNFSAIERFHFAALLLQGLRIAVPA
                     ALLVAVPTEAVQSVLKAMPAWLNEGMQIGGAMVVAVGYALVINMMATREVWPFFALGF
                     ALAAVTQLTLIAMGVIGVAIAFIYLNLSKQGGNGGGRAGSADPIGDILEDY"
     gene            complement(26301..27293)
                     /gene="manX"
                     /locus_tag="TV188_001103"
     CDS             complement(26301..27293)
                     /gene="manX"
                     /locus_tag="TV188_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEL1534469.1"
                     /translation="MGIGIIIASHGKFAEGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYGHFNNAIAQFDADDEILVLADLWSGSPFNQASRVAGENPDRKMAIITGLNLPMLIQ
                     AYTERLMDANAGVEQVAANIIKESKDGIKALPEELNPVEEASTANGGGQALQGAIPKG
                     TVIGDGKLKINLARIDTRLLHGQVATAWTPASKADRIIVASDSVAKDELRKQLIKQAA
                     PGGVKANVVPINKLIEASKDPRFGNTHALILFETVQDALRAIEGGVEIKELNVGSIAH
                     STGKTMVNNVLSMDKDDVAAFEKLRDLGVSFDVRKVPNDSKKNLFELIQKANVQ"
BASE COUNT         7779 a         5336 c         6623 g         7737 t
ORIGIN      
        1 aacggtatca attggataac aaactctttt ttctggtacc cattgttcta tttttgcaag
       61 gggctaccag acctcttgtc tctgatagct ttctcttttt gtttgtgata aaatataaca
      121 catattgagg aggtgtgcca tgaaagctat cattacagtt gttggtaagg acaatcaagg
      181 gattgtcgca ggtgtttcag gacaaattgc tgcattaggg ttaaatattg atgacatttc
      241 acagaccgtt ttagatgatt attttaccat gatggccatt gtctcaagca gtgaaaagca
      301 ggattttgct catctgcgtg aggtgcttca ggcttatgga aagcaattgc aggtgacgat
      361 taatattcaa agcgcagcga tttttgatgc tatgcataac atataaggag cttgatgact
      421 atggatatta gacaggttcg tgaaacagtt gagatgattg aggagcagca ttttgatatt
      481 cgtaccatta cgatgggaat ttccttgctg gattgtattg attcggatat tgatagagct
      541 gccgctaaga tttaccaaaa gattacgaca aaggcagcta atcttgtggc ggttggtgat
      601 gacattgcag cagaactagg tattcccatt gttaataagc gcgtctctgt aactccgata
      661 gcccttattg gggcggcaac agacgcagaa gactacctgt cgcttgcaaa agctctggat
      721 caggctgcct gtgatatcgg agttgacttt atcggtggct tttcagctct tgtgcaaaaa
      781 ggctatcaaa agggtgataa gattttgatt gagtctattc ctcaggcttt ggctcaaaca
      841 cagaaggtct gcgcttcggt caatgttgga tcaacaaggt ctggtattaa tatgacagca
      901 gttgcagaca tggggcgtat catcaaggaa accgccaaag cctctgagat aggggcagca
      961 aagctagtag tctttgctaa tgctgttgag gacaatcctt ttatggcagg agcctttcat
     1021 ggtgtcggtg aggcggatac ggtgattaac gttggtgttt caggacctgg tgtggtcaaa
     1081 agagccttgg aaaaggttcg tggtgaaagc tttgacgttc tagccgagac cgtcaaaaaa
     1141 acggccttta aaatcacgcg tatcggtcag ctagtgggac agatggcaag tgagcggcta
     1201 ggtgtgggct ttggtgttgt ggatctgtcg ctagctccca ctccagcagt tggtgactct
     1261 gtggcacgtg tcttagagga gatgggactt gaaatagttg gcacacatgg cacgacagct
     1321 gccctagctt tacttaatga cgcagtcaaa aagggtggtg tcatggcttg caaccgagtg
     1381 ggtgggttgt caggtgcctt tatccctgta tcagaggacg agggcatgat tgcagcagtg
     1441 cagggaggct cgcttaatct tgaaaagcta gaagccatga ctgccatttg ctcggttggt
     1501 ttggatatga ttgcgatccc agaggagaca ccgtctgaaa ccattgcagc catgattgct
     1561 gatgaggcag ctatcggggt gattaatcaa aagacaacag ctgttcgtat tattccaaag
     1621 ggtaaggagg gtgatatgat tgcttttggt ggtcttttag ggacagctcc ggttatggct
     1681 gttaatccgc attcatcggc tgactttatt gctcgtggtg ggcagatacc agctcctatc
     1741 catagcttta agaattaacg gctagcactt gcatggtttt gcaagtgttt tcttttaatg
     1801 ctataatagc agagagactt tggaggttca ttatgacaaa aacaagatta tacattgtca
     1861 gacatggcaa gacgatgttc aacaccattg gtcgtgcaca gggttggagt gataccccct
     1921 tgacaaaggc aggagaagaa gggattcgtg aattgggact tggtttgaag gctgctggta
     1981 ttccattcaa ggctgctttt tcgagtgatt caggtcgtac catgcagaca atggagatta
     2041 ttctacgaaa gtctgaaaat gagtttttac cctacactag agataagcgg attcgtgagt
     2101 ggtgctttgg tagtctagat ggggcttatg attccgagct gtttttaggt gttttaccta
     2161 gaacaaaggc ctttgaaaat cgtgacaatc tgcgtgatgt gccttattca gaattagcag
     2221 agagtattgt cgaggttgat actgctaact gggcagagcc ctgggaggta ttgagcaagc
     2281 gtatctatga gggctttgag gctatcgcgc ttgctgttga aaatgcagga ggtggcaatg
     2341 ctatcgtggt tagtcatggc atgaccattg gaacctttat gtggctaatt gacccagata
     2401 gggaaaagca atacattgac aatggaagcg tcactgttgt ggaatatgag aatgggcagt
     2461 ttaccatcaa aacgattgga gatatgagct accgctatcg tggtcgtgag ataattgagt
     2521 caataagaga tgaagaataa cactataaga gtccttttac aggccttggt cgtcctgttg
     2581 tttttatcag gggtttacct ctttatcaag cctgaaaaac aggctgtagg ccccaaggct
     2641 aatcaaacag tacctgcccc aaaggcagct aagcaggcta aaaagactac tgatctgcca
     2701 aaggtatcaa ctacggactg gcagctggtc cttgtcaatc gcgatcaccc tcaagaggaa
     2761 atgagtcctg agttggttga gattaatggg attcctattg ataagcgcat tgagcaggag
     2821 acggctgatt ttctagcagc ggcgcagacg attgaacctc aggagcactt gattgctggt
     2881 tatcgttcgg ttgtccagca agaagagctt tatcagtctt atattgccca agagctggca
     2941 aatgatccta gcctgaccca agaggcagct gaagccttgg ttcggaaata tgcccagcca
     3001 gcaggcacta gtgaacatca gactggtcta gccattgata tgagcacagt agataactta
     3061 aacgctagtg atcctaaggt ggcacaggag attcaaaaaa tagctccaca atttggtttt
     3121 attttgcgct atccaaaagg gaagcagact agcacaggga ttgagtatga ggactggcat
     3181 tatcgctatg ttggtaaagc ctctgcccta tacattaccg ctcatagcct cagcctagaa
     3241 gaatacctaa cacgattgaa ggagaaaaaa tgagaaaacg acttaaattt tcctattttc
     3301 tagtgttttt agtgttcatt atggtggctt tgattggtcc cttgctgttc aatgccaaag
     3361 gcacatcggc cagtcaggag atgtctgttc cctatacaga gaggcaattt atccagttgg
     3421 ttgctaagga ggtcaagcca ttggccaaaa actatggcat tcgtccttct attttgattg
     3481 gtcagattat tttagaaacc aattatggca gaaccctgtt ggcggccaaa taccacaacc
     3541 ttttttcact gcagccagct ccagggcagg cttccattag cctcaagaag caagcagcct
     3601 caaagcacaa gacagcctat gctatctatc gggacagaga ggactctatc agagcttact
     3661 tatcatggct tagtcaaggc acaggcgagg agaaaaagct ttaccaaagc ctagcaaccg
     3721 aaaaagggta taaaaaacct gctaaaagtc tgcagaccta tcgctattct gatgataagg
     3781 gctatgccca aaggcttgtg cagctgattg aagcaagagg tttgacaagc tatgatgatt
     3841 gaggagatga aaaagacacc gaaacaaccg gtaagctcag gtatttgctt tagtaggtat
     3901 tgcaactttc tatcagcttg aaggtgtaag ccttaagagt aggagctgtg agcacgcagc
     3961 ctgatttatc ctgctctact aaaggcttga ttgttaggcc ttaaggcttc aggcagttaa
     4021 gctaatcccc cttacagctt agcgctcctt ttagctagcg agtcgggaga agccaatacc
     4081 agtctgagag gtagtaagtg gctctctatt acttctttca agcataatgt caaaggcaac
     4141 actgtcaatg ttttataaaa attagcactc taaaaaaaga gtgctaattt tttgagtttt
     4201 tttcttgaca tgctagttta aaaggatata atagaattat aaattagcag tccgatgtat
     4261 agagtgctaa cagaaaggga gtgattggtt tgtgatcaca gagagacaat ctaatatttt
     4321 gaatcttatt gtagatttat ttacacagac ccatgaacca gttggctcta aggctttgca
     4381 gtcacttatt gcttctagta gtgccactat tagaaatgac atggcaaagc ttgaaaaact
     4441 aggattgctg gagaaggctc acacatcaag tgggcgcatg ccaagtgcgg caggctttaa
     4501 atattttgta gagcattctc ttaatcttgg cagcattgat gagcaggacc tttatcagct
     4561 ggtcaaggcc tttgattttg aggcctttaa gctggaggac gttttgctaa gagccagcca
     4621 gatgctatcg gatacgaccg gctatacggc ggcgatttta gatgttgagc ctgcaaggca
     4681 aaggctgaca ggctttgata ttgttcagct atctagtcat gatgccttgg cagttttgag
     4741 cttagatgag tccaagccgt tgaccgtaca gtttgccatt cctaagaatt ttatgaatcg
     4801 tgatttgctg gtgcttaagg gcattgttgc tgatcgctta cttggcaaag atgttatgac
     4861 tgttcattac aagctgcgaa ccgaaatccc tcagattgtt cagaagtatt ttacggtgac
     4921 agacaatgtt ttggatttgt ttgattatat ctttgtcggg ctttttcgag aaacgatttt
     4981 tgtctctggc aaggttgctg cccttgacta tgctggtctt gcgacctatc agtttcttga
     5041 tgaggagcag cgcttagccc tatctatcag acagagtcta tcagaggaag agatggcaac
     5101 ggttcaggtt gctgacagca gtgagccagc cctagcaaac gtgaccttgc tgacctacaa
     5161 gtttttaatt ccatacagag gatttggcct cttaagctta attgggccag ttgatatgga
     5221 ttatcgtcgt agtgttagct tgattaatgt gattggtcag ctactggctg tgaagctaag
     5281 agattattac cgttacttaa acagcaacca ttatgaggtt cactaaggcc ttaatatgat
     5341 ttaagaaaat gtaagaaagg ggtagacacc ttgtctaaaa aaccaaaaga agagctcaag
     5401 gatcaagagg acattcttga tgaggctgct gaggaagcag tagagccagt tgaagaagct
     5461 gatcaatcag ctgagcttat tgctgatgaa gcagccgagg aaccatctga gctagagttg
     5521 gctctccagc gagcagaaga ttttgaaaat aaatacctca gagctcacgc agaaatgcaa
     5581 aatattcagc gtcgtgcgaa tgaagaacgc caaagcttgc agcgctatcg ttcacaggat
     5641 ttagctaaaa aaatccttcc aagcttagat aacttggagc gtgctttggc tgttgagggt
     5701 ctgacagatg atgtcaaaaa aggcctagaa atggtgcaag aaagccttgt tcaagccctt
     5761 aaagaagaag gtattgaaga ggttcctgtg gaagcctttg accacaatct gcacatggca
     5821 gtccaaaccc taccagcaga tgatgaccac ccagcagata gtatcgctca ggttttccaa
     5881 aaaggctata agcttcatga gcgcttacta agaccagcga tggtggttgt gtacaactag
     5941 tcactaatga tggccattga aatggctcgt cattagacgg caaccgctgt ggcggcttgc
     6001 ctagactcct tactagctcg atagcaaaat ggtatcgatt ttgctatctc acgtcgcaat
     6061 tatcccgtga tgatagctaa tcaataaaat gaatcatgtc cgaaatgacg gtaaactatg
     6121 aaaataagaa ataagattgc tgctttttgc gctagcaaaa gcgaacgaag tgagcattac
     6181 cgatactctt cgccgtggca aaagtcataa aacactagtg ttttatgact cggaaaattt
     6241 gagactttag gctcaaattt cagctatgag attccatagg aagctgctag cgtccgtgcc
     6301 acataagagg agtatcataa atatataaaa gaggaaaaaa tattatgtct aaaattatcg
     6361 gtattgactt aggaacaaca aactcagcag tagcagttct tgaaggaaca gaaagcaaaa
     6421 tcattgccaa cccagaaggc aaccgcacaa ccccttcagt agtgtcattt aaaaacggtg
     6481 aaatcattgt cggtgacgct gccaagcgtc aagcagtgac aaaccctgac actgttatct
     6541 caatcaaatc aaagatggga acctctgaaa aggttgctgc taatggtaaa gaatacacac
     6601 cacaagaaat ctcagcaatg attcttcaat accttaaagg ctatgcagag gactaccttg
     6661 gtgaaaaggt aacaaaggct gttatcacag ttcctgccta cttcaacgat gcacaacgtc
     6721 aagctactaa ggacgcaggt aagattgctg ggcttgaggt agaacgtatc gtcaacgaac
     6781 caactgcagc agctcttgct tacggtcttg acaagacaga taaagaagaa aagatcttag
     6841 tctttgacct tggtggtggt acctttgacg tgtctatcct tgaattgggt gatggtgtct
     6901 ttgatgtgct tgcaactgct ggtgacaaca agctcggtgg tgacgacttt gaccaaaaaa
     6961 tcattgattt cttagtagca gaattcaaga aagaaaacgg tattgaccta tcacaagata
     7021 aaatggctct tcaacgcttg aaggacgctg ctgaaaaagc taaaaaagac ctttcaggtg
     7081 tcactcaaac tcaaatttca ttgccattca tcactgctgg cgctgctggt ccgcttcact
     7141 tagagatgag cctgtctcgt gcaaaatttg atgacctgac tcgtgattta gtagagcgta
     7201 cgaaggttcc tgttcgccaa gcgctgtctg atgcaggctt gagcttgtca gaaatcgatg
     7261 aggttatcct tgttggtggt tcaactcgta tcccagctgt ggttgaagct gttaaggctg
     7321 aaactggcaa agagccaaac aaatcagtga accctgatga agttgtagcg atgggtgctg
     7381 ctatccaagg tggtgtgatc actggtgatg ttaaagacgt tgttcttctt gacgtgacac
     7441 cattgtcact tggtatcgaa acaatgggtg gcgtctttac aaagcttatt gaccgcaaca
     7501 caacaattcc aacctctaaa tcacaggtct tctcaactgc agcagacaac cagccagctg
     7561 ttgatatcca cgtgcttcag ggtgaacgcc caatggcagc agataacaaa acacttggac
     7621 gcttccaatt gacagacatt cctgcagccc ctcgtggtat cccacaaatc gaagtaacct
     7681 ttgacatcga caaaaacggt attgtttctg ttaaggcaaa agacctaggt actcaaaaag
     7741 aacaacatat tgtcatcaaa tctaacgatg gtctttctga agaagaaatt gaacgcatga
     7801 tgaaagacgc tgaagccaat gctgaagccg atgcaaaacg taaggaagag gttgacctta
     7861 aaaatgaagt tgaccaggct atctttgcaa ctgaaaagac tattaaagaa actgaaggca
     7921 aaggctttga cacagagcgt gatgctgctc aaacagctct tgatgagctt aagaaggctc
     7981 aagagtcagg cgaccttgat gatatgaaag ctaagcttga agcgcttaat gaaaaagcac
     8041 aagcccttgc tgttaaaatg tacgagcaag cagccgcagc acaacaagcc caggctggtg
     8101 cagaaggtgc agcagataca ggctcaacaa acagtggcga tgatgttgta gatggtgagt
     8161 tcactgaaaa ataagctgtg aggagctaag gtcgctcagt aaagctagaa actgaggcga
     8221 tagtcccctc ccctaattgc tagaaaatag catagcaagg ctaaataaat aaaaatcaaa
     8281 taggcggggc gcctcgctcc gtctgttttt gtcaatgaag gaaagaataa atgaataata
     8341 cggaatacta tgatcgtctt ggggtctcaa aggacgcttc ggccgatgat attaaacgag
     8401 cttaccgtaa gatgtctaag aaataccacc cagacatcaa taaagagccg ggagctgagc
     8461 aaaaatataa ggacgtacag gaagcctatg aaaccctaag cgattcacaa aagcgtgcag
     8521 cctatgatca atacggggca gccggagcaa acggtggctt tggtggtggc gcaggcggtt
     8581 ttggcggctt cgatggtggt ggctttggcg gctttgagga tattttctca agcttttttg
     8641 gcggtggtgg tatgcgtaat cccaatgctc cacgtcaggg cgatgacctt caatataggg
     8701 taaacctttc ttttgaggaa gctgtttttg gtaccgaaaa agaggtcagc tatcatcgtg
     8761 aatcaacctg tagcacctgt gcaggctcag gagctaagcc tggaacaagt cctacaacct
     8821 gccgtaaatg tcatggctca ggggttatca atgttgatac gcagacccca cttggcatga
     8881 tgcgtcgtca ggtgacctgt gatgtctgtc atggcagcgg tcaagaaatc aaagagcctt
     8941 gccatacctg tcatggaact ggtcatgaaa agaaggttca taaggtttca gtaaaaatcc
     9001 cagcaggtgt tgaaaccggc caacaaatcc gcctacaggg tcagggggaa gcaggcttta
     9061 atggtggacc ttatggtgat ttgttcgtta ttttaaacgt gcttccaagt aaacagtttg
     9121 agcgcaatgg ctctactatt tactacagct tgaatatttc atttgttcag gctgctttgg
     9181 gagatacagt agatatccca acggtccatg gtgatgttgc catgtctatt cccgctggaa
     9241 cacaaactgg taaggtattt cgcttgaagg gcaagggggc tcctaagctt cgaggcggag
     9301 gccaaggaga ccagcatgta actgtaaaca ttgtaacgcc taccaagctc aatgaggctc
     9361 aaaaggaggc cttgaaggct tttgcggagg ctagtggcga aaagccgatt gctccaaaga
     9421 aaaaaggttt ctttgacaag gtcaaagacg ctctagagga tatttaagcg ggtcttgttt
     9481 acacactcta tgagcgattg atcacaattg tatagaatgg ttgagcatag cacatgccaa
     9541 agtttcagag tctaggacac ttttgtctta ggctctttta ttagaggtat agaggctagg
     9601 tctgagcttg gttttagggc tgcatgcttt aaattgcgca gtcaatttta atgtattttt
     9661 tacaatcttt ttcttgcata acgactgatt ctagtgtact atagtctagt aattaatttg
     9721 attgtcaaat tatttggtca taaaattatt tggtaatcaa ataagctgtc agaaaagagg
     9781 agtgatatga cgtttcaaaa tatcattttt gagcttgaag aggatctggc cattttaacc
     9841 ttaaatcgtc cagaggtgtc taatggcttt aacattccag cctgtcagga gattctggag
     9901 gctattaggt tggttaagga taacccctct ctgcgctttt tagtgattaa ggcaaagggc
     9961 aaggtctttt cagtcggtgg tgacttggtt gagatgcaaa atgctgttga aagagatgat
    10021 gttcagtctc tagttaggat tgctgagctg gttcaggata tttcctttgc tatcaagcaa
    10081 ttgccaaagc cggttatcct ctgtgctgat ggtgcggtgg ctggtgcggc ctttaatatt
    10141 gccttagcgg tggatttttg tattgctagc acccagacaa aatttattca ggcctttgtt
    10201 aatgtcggct tagcgccaga tgctggtggt cttttcttgt taacacgtgc cgttggtcta
    10261 aatagagcga ctcatctggt gatgaccggt gagggggtca cagcagaaaa agggcttgag
    10321 tacggatttg tctatcgagc tgctgagtca gataagcttg ataagacctg tagtcagctg
    10381 ttaaagcgtt tgaggcgtgg ctcttcaaat tcctacgccg gcatgaaatc tttggtatgg
    10441 caaagctttt ttgcaggttg ggaggattat gcccaaaaag agcttgctat tcaagaggaa
    10501 ttggccttta aggaggactt taaagagggc gtcagggctt atggagatag gaggcggcca
    10561 aattttcggg ggaaatagct cttatgtgct tgcaaaatac tttgatgtct gatatacttt
    10621 gatagtcaaa gtattttaca gctagggagg tgtttacttg gaatataata agattaatca
    10681 atatttagtt gatattttca acagaatttt ggttattgag gaaatgagct taaaaacaag
    10741 tcaatttaat gatgtttctc taaaggagat gcacacaatt gagattattg gaaaatatca
    10801 gcaggtaacg ccaagtgaca tcgcaagaga gctcatggtt accttaggaa cggttaccac
    10861 tagcttaaac aagctagagc taaagggcta tattgaaaga acaagatcaa gcgtggatag
    10921 acgggttgtt tacctgtcac tgaccaaaaa ggggcgtctt ctggatcgtc tccatgcaag
    10981 attccataaa aatatggtcg gtcatgtgat cgctgatatg aatgaggacg aaatgcaagc
    11041 cctgttacgt ggcttgggga acttacatca gtttttggag gatttggttt aatggtcttt
    11101 tcaaaaatta gtcaggtagc tcattatacg cctaagcagg ttattagtaa tgacgatctg
    11161 tcgcaaatca tggacaccag ccacgaatgg atttcgtcac ggactgggat tgagaagcgt
    11221 cacatttcca ctgtggagat gaccagtgat ttagccattc gggtagcaga gcaattgtta
    11281 gcagggtcag gatatgatgc gactgcactt gattttatca tcgttgctac gattagccca
    11341 gatgctagca tgccatcgac ggcagcaaag gttcaggctg ctatcggtgc tactaatgca
    11401 tttgcttttg atatgacagc ggcctgcagt ggctttgtct ttgccttagc aatggcggat
    11461 aagttgattg catcaggggc ttatcaaaga ggcttggtta ttggagcaga gaccctgtct
    11521 aagattattg attggcagga tagaagcaca gctgttttat ttggagatgg tgctggtggg
    11581 gttttattag aggccagcga gcagcagcat tttctagctg aggccttaca tactgatggt
    11641 gcgcaaggtc aaagcctgac atcaggtcag agcagtctgc gctcaccatt ttctcaagga
    11701 caggaggtca actcctttct tcagatggat ggtcgtgcta tctttgactt tgcgattaga
    11761 gatgtttcaa ggagcattac agcaattatt gagcaatcag gcttggccaa ggaggagtta
    11821 gactatctgc ttttacatca ggccaatcgg cgtattttag ataagatggc taagaaaatt
    11881 ggtatgccaa gagagaaatt tctggaaaat atgatgcact atggcaatac cagtgcagct
    11941 agtataccga ttttgctatc tgaatcagtc caaaatggac agcttaaatt agacggcagc
    12001 cagcatattt tactgtcggg cttcggtgga ggtttgacat ggggcagtct aattgttaaa
    12061 atctagttat atcatgtgcc tagcacattt ataaaataaa tatttatatt aaggagacat
    12121 aaaatggcag tatttgaaaa agtacaggaa attatcgttg aggagcttgg caaggacgca
    12181 gaggaagtaa ccttagaaac tacctttgat gatttagatg ctgactcact tgatgttttc
    12241 caagtgatct cagaaattga agatgccttt gacattcaaa tcgaaacaga agaaggctta
    12301 aacacagttg gtgaccttgt tgcctacgtt gaagaaaaaa caaaataaag ctcaaacaag
    12361 cgagaatact gattaaccag cctgctgatt aatgaactgc tttagttggt caattgatat
    12421 gtaataatcg aaccatcagg gtgagattag accctctttc aggctctaac tcgctctttc
    12481 ttcttattat gatagtttga ttatcaaatt attctcctga tttctttgca tagaaggtta
    12541 ttatgaaaac acgtattaca gaattactta atattgatta tcccattttt cagggaggta
    12601 tggcctgggt ggctgatggt gatctagcag gtgctgtctc caatgctggt ggtcttggga
    12661 tcattggtgg aggaaacgct cctaaagagg tggtcaaggc aaatattgat cgtgtcaaag
    12721 cgatcacaga taagcccttt ggggttaata tcatgctgct atctcccttt gcagatgaca
    12781 ttgtcgattt ggtgatcgaa gaaggtgtca aggtggtgac cactggcgct ggaaatccag
    12841 ggaaatacat ggagcgcctt catgaggcag gtattatcgt gattccagtt gttcctagcg
    12901 ttgccctggc taagcgcatg gaaaaattag gcgttgatgc tgttattgct gaaggaatgg
    12961 aggctggtgg ccatatcggt aaattgacaa cgatgacctt ggttaggcag gtggtagatg
    13021 ctgtttctat tccagttatt gcagcaggtg ggattgcaga tggtcgaggt gcagcagcag
    13081 cctttatgct gggtgctgag gctgttcagg ttggaactcg atttgttgtg gcaaaggaat
    13141 ctaatgctca ccaaagcttt aaggataaaa ttttgaaggc taaggacatt gatactgtca
    13201 tttcagctca agttgttggt catccggtac gctctatcaa aaataagcta acatcagctt
    13261 atgctaaggc tgaaaaagaa tttttagcag atcgtaaggc tgctagtgac atcgaagaaa
    13321 tgggagcagg agctctgcgc aacgctgtga ttgatggtga tgtgatcaat ggctctgtca
    13381 tggcagggca gattgcaggc ttaattagag cagaagaaag ctgtgaagcc atcctaaagg
    13441 atatctacta tggtgcagca gcagtgatta gtcaagaagc taagcgctgg caagctcttg
    13501 cagctgatga caaaaacgaa acgatataaa taaggagaag tatgacaaaa acagcctttt
    13561 tatttgctgg tcagggtgct cagacactag gcatgacaag agatttgtat gaccaatatg
    13621 ccattgctcg tgacaccttt gatcaggcta gtcagctttt aggctatgat ttacgcaagc
    13681 tcattgatac cgaccaggat cggttgaacc agacagccta cacgcagcca gcaatcttaa
    13741 ccgcttcagt ctccatttat cgtatcttaa cctcttatgg ggttcatcct gatatggtgg
    13801 cggggctttc tcttggagaa tattctgctc tagttgcggc aggtgttctg agttttgaga
    13861 ctgccctaga gctagttgca aaaaggggac gctttatgga ggaggcagcg cctgctggct
    13921 ctggtaagat ggtagctgtg atgaatacag aggctaggct tattgaggag gcttgtcaag
    13981 aggcttcttc ggttggtgtt gtgtcacctg ctaactataa tacgccagga cagattgtta
    14041 ttggtgggac agctgaggct gtcaatgcgg cacttgaaat cttaaaagca aagggagtga
    14101 agcgtttaat tccgctgaat gtctcaggac ctttccatac agcactttta gcgcctgcta
    14161 gtcaaaggtt ggcagaggag ctcagcaaga ttcaatttca ggactttgat ctgccactgg
    14221 ttggaaatac agaggctaag gtcatggaaa aggatcggat tgcagaatta ttggcgcgtc
    14281 aggtcatgga gcctgttcgt ttttatgata gtatcgaggt tatgaaggct aacggtatca
    14341 cccagtttgt tgagattggc cctggcaggg ttttaacagg ctttattaaa aaaatcgaca
    14401 aaaagctgct atgcagcagt gttgaagata tgccaagcct acaattgtat ttgggaaaat
    14461 aggagggaat gctaagctat ggaaattaaa ggaaaaaacg tttttatcac agggtcaaca
    14521 agaggcattg gactagcaat ggctcatcaa tttgcaggac taggcgccaa catcgttctc
    14581 aatggtcgct cagcgatttc tgatgagctg gtggagacct ttaaggatta cggtgtgaag
    14641 gttgtgccga tctcaggaga tgtttcagag ggggctgatg ctaagcgaat ggttgatgag
    14701 gctattgagc agcttggctc tgtggacatt ttgattaaca atgctggcat cactaatgat
    14761 aaattaatgc ttaagatgtc agaggaggac tttgagcgtg ttctcaaaat caatctgaca
    14821 ggagcattta acatgacaca atcggtctta aagccgatga caaaggctcg tcagggtgct
    14881 atcatcaatg tgtctagtgt tgtcggccta acaggaaata tcggtcaagc aaattatgca
    14941 gcgtccaagg caggcttgat tggctttacc aagtcagttg ctcgtgaggt tgcggcgcgt
    15001 ggcattcggg taaatgcgat tgcaccgggc ttcatcgaat ctgatatgac aggtgtcctt
    15061 tctgaaaaga tgcaagagca aatcttaaat caaatcccaa tgaagcgtat tggcaagggg
    15121 caagaggttg ctcaggcagc aagcttccta gctagtcagg attatattac tggtcaggtg
    15181 cttgccattg acggcggcat gacaatgcaa taaaatagag gtattaaaat gacattaaac
    15241 agagtagttg taacaggtta tggcgtgact tccccaattg ggcatactcc agaggagttt
    15301 tggtcaagct taaaggcagg tcatattggt attaagccta tcacaaaatt tgatacgagt
    15361 gacttcgctg ttaagaatgc agcagagatt caggattttc catttgataa gtattttgtc
    15421 aaaaaggatc taaatcgctt tgacatgtat tccttgtatg ccttatatgc tgcgacagag
    15481 gcgattgaac atgctggcct agatattgaa gcgattgatt ctgaccgctt tggtgttatt
    15541 gtagcgtctg gtattggagg cattcaagag attgaagagc aggtgattcg gttacatgaa
    15601 aaaggaccaa agcgcgttaa gccgatgact ctaccaaagg ccttgccaaa tatggcggct
    15661 ggtaatgttg ccatgaagct gaatgcccaa ggcgtatgta agtcaatcaa tacagcctgt
    15721 gcctcttcaa acgatgctat tggcgatgcc tttcgtacaa ttaagtttgg tcttcaagac
    15781 gtgatgatgg ttggaggatc agaggcagcc attacaaaat ttgccattgc gggcttccag
    15841 agcttgactg ccttgtcaac aactgaggac ccaagccgca gctctattcc atttgataag
    15901 gatcgaaacg gttttatcat gggtgaagga tcaggtatgc ttgttttgga aagcttagag
    15961 catgctcaaa agcgcggtgc gactatttta gctgagattg ttggctacgg caatacctgt
    16021 gacgcttacc acatgacctc accacaccca gaaggacttg gtgctcgtaa ggccattaat
    16081 ctagcattgc aggaggccgg tattgatgca gcagctattg actacgtgaa tgctcatggc
    16141 acctcaactc ctgctaatga aaaaggagaa agtcaggcta ttgttgcagt gcttggtaaa
    16201 gaggttcctg tctcatcaac caagtccttt acaggccacc tactaggggc agctggtgct
    16261 gtggaagcta ttgcaaccat agaagcaata cgtcacaatt atgttccaat gacagctggg
    16321 acaaaggagc tgtcagatga tattgaagca aatgttattt ttggccaagg aaaagaagcc
    16381 gatattcgtt atgccatgtc aaataccttt ggctttggag gtcataacgc tgtattagcc
    16441 tttaagcgtt gggaggatta aaatgaatat tcaagagata aaggatttga tggcacagtt
    16501 tgatgcgtca agcctacgcg aattttcatt caaatcaagt gatggggagc tgttatttag
    16561 taaaaatgag caccgtccga tggcagctcc agctcctgag cctgttactt tgcaccagga
    16621 ggtagcccct attagcctga cgcaggagat tgtctctaaa caggaatcaa tccctgcttc
    16681 ttcaggtctg caagagccag aaggagaagt agttgacagt cctcttgttg gtgtggccta
    16741 tcttgctgcc ggtcctgaca agcctccatt tgttactgtt ggtgatagcg ttaaaaaggg
    16801 acagacattg ttaattgttg aggcgatgaa ggtcatgaac gagattcctg ctccttgcga
    16861 cggtatcgtg acagagattt tagtggccaa tgaggacgtg gttgagtttg gacaaggatt
    16921 ggtacgcatt aaatgatgga tataaaacag attcaagagg cattgccaca tcgctaccca
    16981 atgctgcttg ttgatagaat tttagaggct tcagacgatg aaattgttgc catcaaaaat
    17041 gtcactatca atgagccctt ctttaacggt cattttcctc agtatccagt catgccaggt
    17101 gttttgatca tggaggcctt ggcacaaact gctggcgtct tggagctatc aaaagaggaa
    17161 aataaaggca agcttgtttt ttacgctggt atggacaagg taaaatttaa aaagcaggtg
    17221 gttccgggag accagctagt catgacagct aggtttatta agcgtcgtgg gacaatagca
    17281 gttgttgagg ccaaggcaga ggttgatggc aaattagcag ctagtgggac cttgaccttt
    17341 gcttttgggc agtaaaagac taatcgtctg tggaggaaaa aagaacctat gtttaacaaa
    17401 atcttaattg ccaatcgtgg tgaaatagca gtgcggatta ttcgtgcagc acgagaatta
    17461 ggcatttcca cagttgctgt ttattctgag gctgatagag aggctttaca tacgatcttg
    17521 gcagaccaag ccatctgtat tggaccgtca agatcaaagg aatcctatct caatatgaat
    17581 tctgtcttat cagcagctgt ggtgacaggg gcgcaggcta tccacccagg gtttggtttt
    17641 ttaagtgaaa attcaaaatt tgtgaccatg tgcgaggaaa tgaacatcaa gtttattggc
    17701 ccctcaggag ctgtcatgga taaaatgggc gacaaaatca acgcccgcgc tgagatgatt
    17761 aaggcaggtg ttcctgttat tccaggctca gacggcgagg tttacaatgc ccaagaggct
    17821 cttgagattg caaggcagat tggctatcca gtaatgctaa aggctgctgc aggcggtggc
    17881 ggcaagggaa tccgaaaggt tgaatccgag gctgatttag aggctgcttt taacgctgct
    17941 agtcaagaag ctttaggagc ctttggtaat ggtgccatgt atttggagaa ggttatttat
    18001 ccggcaaggc atattgaggt gcaaatttta ggtgattcac aggggcatgt gatacacctt
    18061 ggagagagag attgctcctt acagcgtaac aatcaaaagg tactggagga aagcccttcg
    18121 attgcgattg gcacaacact gcgtcaaagg atgggtgaag ctgctgttcg tgctgccaag
    18181 gcggtgtcct atgagaatgc tggcacaatt gagttcttat tagatgaagc cagcggtgat
    18241 ttttacttta tggagatgaa tacgcgtgtt caggtagagc accccgtaac agagtttgtt
    18301 acaggcgttg acattgtcaa ggagcaattg cggatcgcag caggtcttcc tttatcagtt
    18361 cgtcaagagg atattgtgat tactggccat gctattgagt gtcgtattaa cgcagaaaat
    18421 ccaagcttta attttgcacc aagccctggt aagattacag atctttacct accaagcgga
    18481 ggtgttgggc ttaggattga ttctgctgtt tacagtggtt atacgatacc gccttattat
    18541 gatagtatga ttgctaagat tatcgttcat ggagataacc gatttgatgc tttgatgaag
    18601 atgcaaaggg ctctgtttga gttagagatt gaaggtatta tgaccaatat tgattttcag
    18661 atggacttga tttcagacaa gcaagtgatt gcgggtgatt acgatacgtc gtttttgatg
    18721 gaaacctttt tacccagcta caataaagat taggagtaga tatggcctta tttagtaaaa
    18781 aagacaaata tatccgtatt actcccaata attctctcaa aagctctgtc agtcgtaatg
    18841 ttccagaggt gccagacgaa ttatttgcca agtgtcctgc ctgtaagcac atgatttatc
    18901 aaaaggatct ggggccggca aagatttgtc cgacctgctc ctataatttt aggatttctg
    18961 ctcaggagcg cttgacttta accgttgatg aaggctcttt tcaggaattg tttacagata
    19021 ttgaaaccaa ggatccatta agatttccag actaccaagc caagctgcaa aaggccaggc
    19081 aggctactgg cttgcatgag gctgtcctga ctggaacagc tctggtcaag ggacaaaggc
    19141 ttgctctagc catcatggat tcgcatttta tcatggcaag catggggacc gttgttggtg
    19201 agaaaatcac tcgcttattt gagctggcta ttagtgagcg gctcccagtt gttattttta
    19261 cagcgtctgg tggagcccgt atgcaagagg gcattatgag tctgatgcag atggctaagg
    19321 tttctgcagc tataaagaaa cattcaaatg ctgggctttt ttacctgact atcctaactg
    19381 atccgaccac aggtggtgtg acagcgagct ttgcaatgga gggtgatatg attattgcag
    19441 agccccagtc cttggttggt tttgctggtc gacgcgtcat tgagacgaca gttagagaaa
    19501 atttaccaga tgattttcaa aaggcagagt tcttaaaaga gcatggcttt gttgacgcta
    19561 ttgtgaagcg gactgacctg cgtgatcgga ttgctcattt ggtggcattt catggaggtg
    19621 tatcatgaca gacgtcgcaa gaatattaaa ggaagcgcgt gaccagggtc gaatgacagc
    19681 tctagattat gccagcctga tttttgatga gtttatggag ttgcatgggg atcgtcagtt
    19741 tgctgatgat ggctctattg ttggtgggat tgcctatttg gctgatcaac cggtcacagt
    19801 gattggtatt caaaaaggaa aaaatcttca agataatctg gctagaaatt ttgggcagcc
    19861 gcaccctgag ggctatcgta aggccttacg cttaatgaag caggctgaaa aatttggtcg
    19921 tccagtgatt acctttatca atacagcagg agcttatccg ggcgtaggtg ctgaggagcg
    19981 cggtcaaggt gaagctattg ctagaaactt gatggaaatg agtgacctca aggttcctat
    20041 cattgctatt attattggcg aaggcggctc aggcggtgct ttagctttag ctgttgctga
    20101 tcaggtttgg atgctggaaa acaccatgta cgctgttctt agcccagaag gctttgcctc
    20161 tattctctgg aaggatggct ctagggctac tgaagctgct gagctcatga aaattaccgc
    20221 agctgagctg tatcaaatgg gcgtcattga tcggattatt ccggagcggg gttatttttc
    20281 gagtgagatt gttgagatga taaaatcaca cttaattgac gaaatcactc agctacaggc
    20341 caagccctta gaggaattat tggatcagcg ctaccagcgc tttagaaaat attaaggaca
    20401 tcaaaaaaga cctctgtaag gctagcagtt agctaggagt tacagaggtc ttctttattg
    20461 ttaggatcaa tctcattaat cggctctttg tccccctaca attgataaag agcctttttt
    20521 gtacatagaa aaaagcccta tcatttctac tgtgtcctta tctactacag aaatgataga
    20581 gcccattaat cgtcttgttg gcaccttatc cggccagtct ttggctttaa cgtggcttga
    20641 tcacctctag tccacccata taaggacgaa gcacttctgg aatcgtcact gagccgtcct
    20701 cattttggta attttctagg atagcagcta cggtacgtcc gacagcaagc ccagagccat
    20761 ttagggtgtg cagtagctta accttgccat ctgcctcatc gcggtagcga atttgtgcgc
    20821 ggcgtgcttg gaaatcttcg gtatttgagc agcttgagat ttcgcgatag gtgttttgag
    20881 cagggatcca aacctctaaa tcataggttt tagcggccga aaagcccata tccccagtac
    20941 aaagagccaa gacacgataa gggagcttta gcttttggag aatatgctcg gcattggcgg
    21001 tcattttttc cagctcttca taagatgttt cgggcttagc aaacttaacc atttcgacct
    21061 tatggaattg gtgtaagcga atcaagccac gagtgtcgcg gccagcagag ccagcctcag
    21121 agcgaaatga tgggctcatt gcagtaaagt agattggcag ctccttacca tctatgatgt
    21181 caccacgata gtaattggtt aatgggactt cagcagttgg gataagaaca aagtttgtcc
    21241 catctagctc aaaggtatcc tccttgaatt ttggatattg accagtgcca aacatagagt
    21301 catgattaac catataagga ggaatgattt cttgatagcc ctcttttagg tgctcatcaa
    21361 gcatgaagtt ataaagggca cgctccagcc ttgcaccaag atttttatag aataagaagc
    21421 gagcaccggt aacctttgcg ccacgctccc aatcaaggat atctaaggct tctccaagat
    21481 cccaatgcgc cttgatgtca aaatcaaact gacgtggctt tccccagcga tgaatctcta
    21541 cattgtcctc ttcatcagct ccaataggaa ctgaatcatg gggagtattt ggcaaaacag
    21601 tgatgatacc ggtaatttct tggtcaatgt cagctagctt agcatcaatt gccttgatgt
    21661 tagcagctag ctgctgcatg tcagcaatct gttggctggc gtcttccttt tggcgtttgg
    21721 cttgagcgat agcagcagag gcgatattac gctgggcttt tagctcttct gtttgaacaa
    21781 gcagggtgcg ccgctgttca tctaaggctt ttagagaggt taggatagct tctgacacac
    21841 cacgtgtttt gagcttagca gcaacagtat caaaatcagt acgaatacgc ttaagatcta
    21901 gcataaataa atctcctttg agctggtgat aagatagtca gttataaaat agcatgagca
    21961 aagctagctg atcgcttttt tatttctgac gagataaaaa agcacagcct atgaatacac
    22021 tggagcgcct aagcgcggtt ccatccagct tcacaatctg tgcacttaat tcatatttaa
    22081 ttggtagacg gtagaatttc gtatgactcc tctatctgtt ttcagcaacc acagactctc
    22141 tgaaagacag agccagacta cttatccgct agacctatta taacaaaaaa ggagaaaaag
    22201 taaactccca aatgagtgtc agctacatca aacgcgcgaa ctagttattt tggaattaga
    22261 gtagacactt tcaatgtttt tcctatagta aagtctataa aaaacaagac atatccttga
    22321 aatacagaaa gctttctttt cttgctaaaa ctttttcatg tgtctgtcac ggagcgtcag
    22381 taatacaaaa ggctgatgac aagtagagct taggtcagag gcacaaaaaa tctcgttgtc
    22441 agacaaaatc aaatcgttaa atattaaaaa ttgtggtaaa ctaatattat gcgtaaaaat
    22501 gtaatgacat tagataagaa ccgccattac ggtttagatt tattgcgaat catttccatg
    22561 tttatgattg tgatcacaca tgttttggga aagggcggct tgcggtcaac tgtcgaaggt
    22621 gaggcagatt cttattttat tgttacctgg atgattcagg ttcttgttta tggggcggtc
    22681 aattgctatg cgttgattag tggctatgtg ggcattaagt cgccctataa atattccaaa
    22741 atcgttaata tttgggtaca agtcttcttt tatagctttc tgatgaccct tttgtttgct
    22801 ctatttggct ttccagttag cttagagaat tggcgtcagg ccctctttcc catagtgagt
    22861 ggcaattatt ggtatatcac cgcctacttt gggttactga tttttatgcc tatgatcaat
    22921 ggtggcctca ataccttatc caataagcag ctaggccgat tggtactgct ggtttttgct
    22981 attttttcgt tgatcccagc tctgatgaac cagcaggtcg atgaattttc cttaagcaag
    23041 ggctttgaaa tgacttggct gattattctc tacattatcg gagcctatct aaggaggata
    23101 gagctaagta ggtttagtca taagcttctt attgcggttt atatgggatc tttggtagtt
    23161 acctatatca tgaaatttat ggtgggaaat atttggtact ggtatgtatc acctagcctg
    23221 accttgggag ctattgcctt atttattctt tttgctaagc tgaagctgac atcagaaaca
    23281 ctgctgctac gctttattgt gatcgtgtct ccaacgactc taggtattta tctggtgcac
    23341 ttacacccct tgctggtcaa atttattatt cgcgattttg cagagccctt tgtcaatgct
    23401 cctatccttt tatacccact actgatattt ggcgtcggca ttgtgattta ttttttgtcc
    23461 tttctggttg aacaggcaag gctgatgctt tttaaaaaac taggctttca aaatttgttg
    23521 aaatgggtgg acaagaaaat cccctttgca gattgatgag gaataaggtt agatttagat
    23581 tgtagaaagg attcacttaa gcttgttttt caagcttttt cttttaatca aaaaaacaaa
    23641 agaattctga aaaatactgt aatatcagca ttttccagag ttttcattat atgatagtca
    23701 atttctaaat tttcaatttt tctatcgctg atagggtttg tctacattct gtaagcttgt
    23761 ttttcaagct tttttgttag caacgaaaaa aactcttaga catattgcta tggtgctatg
    23821 tctaagagta ttatcatgct ggtctatgac cgtaatattg aattaaggca ggcccatcaa
    23881 tgagatttct tatccttttt ttgatgatga aatagctttg ctattatggt ctggaccaag
    23941 gttggtagct tgatgacctt gtcattgcca attgtttctc tagcaacctt caagattttt
    24001 cctgaatcct ttgaagcaaa gagaaatttg ccttgatcgg taaagatttc aaagtgacga
    24061 ctgacctttt tgccagaaac attggcaccg atttggttaa tggccgtcca gggaatttga
    24121 atgaagtcct caacgttttt atcattgtaa aattccaaag ccttatctcc aagtaagatt
    24181 ttcccaacct ttcctccgat tccaagatag gagacggctg ttgtctgaag gatcaccctt
    24241 tgatttaaag attgtgccat aataagtcct ttagtgtttt tgtctattat aacataaaaa
    24301 tatagcttgt agcaggctga atactggcct ttgctaaggc tctagacagc caaaaattaa
    24361 ggaactggga agcccccaat tccttaattt ttattacatg atgtgaagaa ggtgtgcgat
    24421 gataccaaat gcaaacaagg caatgatgat tgcgattggt gatacttttt tcttcaataa
    24481 ccacatgcaa aggaaggtaa gtagtaatcc agcaagtcct gggatcaatg agtctaattg
    24541 cccttgaagg gtttgtgatt gaactttatc aaggctcatg ccacccatag cttgtccaag
    24601 aatacttttt agctcagcac ctttaacggc tccctcaggg aagacaacat aggcaccttc
    24661 agaaagctgc ttgcctggaa ggttgatggt aaagttgata gatacccagc gttgtacaag
    24721 gacagcaagg ataaacatac caaggataga agctccctta gtgatgtctt gtaggatacc
    24781 acctgacatg tctttggtga tttcagatcc agccttgtag ccaaattctt gagtgtacca
    24841 caagaaggcc atacggataa tgttccagcc aaagaagaaa aggagtggac cgacaaggtt
    24901 accagtttgt gcaagagaag caccaagagc accaaggata ggacgcactg taaaccagaa
    24961 gacaggatca ccgatacctg caagaggtcc catcataccg atcttaaccc cttggatagc
    25021 agcgttgtca atagcagtac cgttggcacg ttcttcttca agggcaagcg ttaccccgat
    25081 gataggagca gccacatatg ggtgagtgtt aaagaattcc atatgacgct caagtgcagc
    25141 agcacgatct tctttagttg tgtaaagctt tttaagtgct gggataagtg cataagccca
    25201 acccatgttt tgcatacgct catagttcca agacccttga aggaattgtg aacgccacca
    25261 aacacgttta cggtcagctt ttgttaattt aatttgttca gtcattaatc ttaccccttt
    25321 ctagtagtct tctaggatat cgccgattgg gtcagcagag cctgctcgac ctccaccgtt
    25381 accaccttgt tttgaaaggt taaggtagat aaaggcaata gccacaccga taacacccat
    25441 agcgataagt gttaattggg tcacagctgc aagggcaaaa ccaagtgcga agaatggcca
    25501 tacctcacgt gtagccatca tgttgataac aagagcgtaa cctacggcaa caaccatagc
    25561 accaccgatt tgcatacctt cattcaacca agctggcata gccttcaaga cactttgaac
    25621 ggcctcagtt ggcacagcaa caagaagtgc agctggtaca gcaatacgca agccttgaag
    25681 aagaagtgca gcaaagtgga agcgctcgat agcagagaag ttaccctcta aagcagcctt
    25741 gtccccagcg tgaacaagta cagttgaaat ggtacgaaca atcatagtaa ggaaaagacc
    25801 tgcaaccgca agaggaatag ctgttgagta tgcaaaggta atcccttttt gagtaaagtc
    25861 gccaccctta accatgataa tagccgctgc aacagatgca agagcagcgt caggagctac
    25921 agcagcacca atgtttgccc aaccaagtgc aagcatttga agagtaccac caagcataac
    25981 acctgcttca aggtgaccag tcacaagtcc gattaaggta cacgcaacaa gtggttggtg
    26041 catttgaaat tggtccaaga taccttcaag accggcaaag aaggcaacga taacgaccaa
    26101 gattgcagaa attaatgaaa tatctgacat tttgttatcc tttcgtatat gagtcaattg
    26161 tcaatggaca atataaagcg ttattaagtg atgatgattt gtctagaagc aatcatcagg
    26221 cttatcatat catcgcagca ttgtagatga ggcagacagc ttgttgcgtt aaacaagcct
    26281 acctcttatt tctaaattgc ttattgcaca tttgcttttt ggataagctc aaataggttt
    26341 ttcttagaat catttggcac cttacgaacg tcaaatgaaa cacctagatc acgtaatttt
    26401 tcaaaggcag caacgtcatc cttgtccata gacaatacgt tgttaaccat tgttttacct
    26461 gttgaatgcg ctattgatcc aacgttcagc tctttgatct caacgccgcc ttcaatcgca
    26521 cgaagggcgt cctgaacagt ttcaaacagg ataagagcgt gagtgttgcc aaagcgtggg
    26581 tccttagaag cctcaatcaa tttattgatc ggaacaacat tagccttaac cccaccagga
    26641 gccgcctgct tgatcaattg cttacgaagc tcgtccttag ccacagaatc tgacgctaca
    26701 ataatacgat cagccttaga agctggtgtc catgcagttg ctacctgacc atgaagaaga
    26761 cgagtgtcaa tacgagcaag gttgattttt agcttaccat ctccaatgac agttccctta
    26821 ggaatagctc cttgaagcgc ttgaccacca ccattagctg tagaagcctc ctcaactgga
    26881 ttgagctctt caggaagggc tttaataccg tccttagatt ctttaatgat gtttgcggct
    26941 acttgttcaa cacctgcatt ggcgtccatc aaacgctcag tataggcttg aataagcatt
    27001 ggcaaattta gaccagtgat gatagccatt ttgcgatcag gattttctcc tgccacacga
    27061 ctagcctgat taaatggaga accactccaa aggtcagcta gtacaaggat ttcatcatca
    27121 gcatcaaatt gtgcgatagc attgttgaag tgtccataca agtcatctgg tccttcattt
    27181 ggcatgaaag tcacaacttg aactttctct tgttcaccaa aaatcataga accagattga
    27241 tgaatacctt cagcaaattt accatggctg gcaataataa taccgatacc cattcttgtt
    27301 cttcctcctt attaaaatat ttttcgttga aatgaagaag aataatctcc ttccaaatag
    27361 catttggcaa ttctttttca cttgaacgaa attcaagaac gtctctattt taaaacgttt
    27421 tcacttaaaa atcaagccct ttcggaaaaa tcttacgaaa tatgaaaaaa ttttc
//
LOCUS       DARYYD010000027        25980 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.027, whole genome shotgun sequence.
ACCESSION   DARYYD010000027 DARYYD010000000
VERSION     DARYYD010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25980
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.027"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..376
                     /locus_tag="TV188_001104"
     CDS             <1..376
                     /locus_tag="TV188_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="secretion protein"
                     /protein_id="HEL1534470.1"
                     /translation="QGGEKKDISYIEQEGDLSALFQSETDLSIKKKQQHRKETSQTTK
                     NHLFMTHIDSDNLVARYQPLLFNPEQRLAATDDQYGVLLAQKTIGITWQMLAILLVGA
                     VLTGYSLTRGRLSRQKHKRHHE"
     gene            692..933
                     /locus_tag="TV188_001105"
                     /pseudo
     CDS             692..933
                     /locus_tag="TV188_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678362.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein"
     gene            936..2093
                     /gene="essB"
                     /locus_tag="TV188_001106"
     CDS             936..2093
                     /gene="essB"
                     /locus_tag="TV188_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HEL1534471.1"
                     /translation="MEKKMKTIIRELLVEDVKGDAEVAYTLLASEHSLFVPSKLEQAF
                     DKLILEASIDDMYDWSALEAMIVEEKLRHLLNLSELFDQLLDSKFTYSFTPDNLVFNR
                     NAEPQLIFRGIKDQVPPYQPLEREVFVNTLKCMTIALLDKKTSYDALMGGKLPFYKGN
                     LFCEAVAKAEALQELQELLATKYHEEQKDNKEHFSRVANKTISRLKLTTICSSVLALL
                     SLAGVLYFLLFAMPYQEMVASLRMAFINQDYSKVITTAKHTDSKALSQGDKYIVAYSV
                     IMTEPLTDKQKEELSKISNQSNEDYLRYWVLIGQARIDDAMDIASYLDDPQLLMYGLT
                     KKIDDVQRDPNLTAEARTEQLNSYKSKLDELKKAYLTPKEEKAAGSSSDKE"
     gene            2105..6481
                     /gene="essC"
                     /locus_tag="TV188_001107"
     CDS             2105..6481
                     /gene="essC"
                     /locus_tag="TV188_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HEL1534472.1"
                     /translation="MTYLIYDDNAYHLYSDTVYQLGPSSGSDIFLPLLEDITLSVEGS
                     GVVLLEESYSTGKHCVALSDEVTVTLLILEAVTKYLLPDSSLYISGETTAALQLLDYP
                     SELVLTLDSDSASCYSPVSYYLNGKWTKGKQPLKASDELVFSDGLVLSFQDQLLSIQS
                     LYAIQTALLPLTEAVAEDRASEFHRSPRIILREPEGKVTIASVPTDDEGKRQSLLKLI
                     ITPLAMIVFTGLSYVFFRGGGMLMMMMGMSVITIGSSIHSYFSDKKWHKEAQQQKIKD
                     YLAYLDTKYVELAGYREEQIEALLYHYPNMTTILEMAQKTDRRIYEKAPYHFDFLTYR
                     LGLGDTPASFHIDYSDSELTKHHEKAKQRVQELIAYYQVTAQVPIQNAIASPIGYIGA
                     RKVVIEQVQQLMMQIATFHSYHDVQFIPIFREEELPLWNWSRWLPHTKLKVLNSRGFV
                     YSQRTRDQLLTSLYQLIKERQLDSEQDKGTEKQYTPHYIVLITDMSLMLDHNIMEYIN
                     EDLSHLGIHYIFVEEVIESLPEHVKTVIDYRGDKHAQLILQEGLYLNKAFTPLQPLSM
                     KDKEVFARHMAGINHVETLRNAIPNSVTFLEMYGVNKVEELNLLKRWKENEAYQTMAV
                     PLGVRGRDDILYLNLHEKAHGPHGLIAGTTGSGKSELVQSYILSLAVNYHPYEVAFLL
                     IDYKGGGMANLFADLPHVVGTITNLDGNQANRALVSIKAELKKRQRIFLENDVNHIDQ
                     YTKLFKEGRVKEPLPHLLIISDEFAELKANQPEFMDELVSTARIGRSLGVKLILATQK
                     PSGVVNDQIWSNAKFKIALKVQDVADSREVIKTPDAAEITQVGRAYLQVGNNEIYELF
                     QSAWSGADYNPKGRHTIQHETTVYEITANGQYQAINKDLSGLDKKREAKSMPTELDAV
                     VAEAQQLFEDLHIPKVASPWLPPLSEKIYASDLQSTHFKDYWGQTQDLQPVLIGYQDI
                     PERQEQSPLYFHMEKAGHILLVSSPGFGKSTFLQGFALDVMRKQTPAQAHFYLYDFGT
                     SGLIALSDFPHVADYFTLDETDKIMKSLRYLSEEIKTRKHALSKAKATNLNQYNQLSK
                     DTFPALFVIIDGFDSVMDAPFVDAVYNVLNVIARDGASLGMYLVVTLSRLNTMRLQLQ
                     SNFKTKLSLFLFDNSDLSSVVGRSNIPLDDIKGRAIMKRDDIIQFQIALPYSSEYYTD
                     YMAEVKREVEAMRAVYQGALPAAIPMLPEKVTPDMIAAMSDSAQDFVIGLEREDVVPA
                     GFTFKKSILMASDSPAFVANYYKLLDFQLQRLADQYRTVILDPSQRIARQFFEDSQRF
                     STALDVGDTLRAIVEDFKKRLAAPGQDYQKWLVVIPDIAATALAAGISEEDFKQLVTE
                     GSQYGVTLIFVGAYQDLVNNTYDNFVKLANQLIEQVFLGMRISDQSHTRYAYISNEPS
                     LRPTQGYILYPEGYDFIQLLEI"
     gene            6494..6823
                     /locus_tag="TV188_001108"
     CDS             6494..6823
                     /locus_tag="TV188_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1534473.1"
                     /translation="MSTVTMLPLGSIVILKGNTKKMMIIARVIAAPIKGEVYRFDYGA
                     CLYPEGMMGDSLIYFNHDDIFKIIQEGYADDDNALMLETIAQALATTDIPKGDVSALN
                     DRKTVED"
     gene            6827..7261
                     /locus_tag="TV188_001109"
     CDS             6827..7261
                     /locus_tag="TV188_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HEL1534474.1"
                     /translation="MGQVDYNHINQLQRQVDQHRASLSTATAEIASIDEKLERLRCAK
                     ASVGAIQGDVHQIKVSVMAKRDQPDWKGERKDRLMSSWEEFSHDYRHFQLELDAYYDA
                     ICDTITRLENQKYEQQGLIGWCQSMINSLGNEIEKLFHIREG"
     gene            7263..7547
                     /locus_tag="TV188_001110"
     CDS             7263..7547
                     /locus_tag="TV188_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1534475.1"
                     /translation="MFGVIQLSEVVFGAHVLSLTAAKASLSDVKASFPSHQSSSKVLD
                     LYQSEFEALSQLVAAYARLLEKDIALIAEAGQELALTDKQLGQAIGFRLQ"
     gene            complement(7618..8920)
                     /locus_tag="TV188_001111"
                     /pseudo
     CDS             complement(7618..8920)
                     /locus_tag="TV188_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400088.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9301..10011
                     /gene="ccdA2"
                     /locus_tag="TV188_001112"
     CDS             9301..10011
                     /gene="ccdA2"
                     /locus_tag="TV188_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEL1534476.1"
                     /translation="MELTMLLMVSVFIAGLLSFFSPCIFPVLPVYLGILLDSDDSRSI
                     TIFGKKLYWYGIVKTLAFISGLSTIFIILGYGAGLLGNILYAAWFRYLLGAFVILLGI
                     HQMEIVTIKKLQFQKSVAFQNKKDRNAVLNAFLLGITFSFGWTPCVGPVLSSVLALAA
                     SGGSGAWQGGFLMIIYTLGLGLPFLLLSFASGIVLKHFNKLKPHIPLLKKLGGLLIVI
                     MGLLLMTGNLNSLSGLFE"
     gene            10025..10675
                     /locus_tag="TV188_001113"
     CDS             10025..10675
                     /locus_tag="TV188_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002933805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HEL1534477.1"
                     /translation="MKKTTFLTTGLACLALLTACSAKDKMAMNDSKKDHMTRTDDKSK
                     MKKDQKDKMSDKKDMMSDDKHMSDADKASKNDGQMAPDFELKSIDGKTYRLSDFKGKK
                     VYLKFWASWCSICLSTLGDTQSLATMKDKDFEVLTIVSPGHQGEKSEADFKKWFEGTD
                     FKDLPVLLDPDGKLLEAYGVRSYPTEIFVGSDGVLAKKHIGYAKKSEIEKTLKEIK"
     gene            10693..11805
                     /gene="msrB"
                     /locus_tag="TV188_001114"
     CDS             10693..11805
                     /gene="msrB"
                     /locus_tag="TV188_001114"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEL1534478.1"
                     /translation="MEHKWKLLLLVFGALVFLGGVLMVFQRGYATSYHNNQVKLPAKG
                     TSQLKKTANAKLPEKKKEIYLAGGCFWGVEEYFSNVDGVLDAVSGYANGRGDTTSYQL
                     LHQTGHAETVQVVYDANRISLKELLLHYFRIIDPTSLNKQGNDRGSQYRTGIYYTDPS
                     DLTTIDMVFQEKASDYKKKIVVEKAPLKSFTKAEEYHQDYLKKNPNGYCHINVNEASY
                     PVIDKTKYPKPSKEEIKKKLSKDEYRVTQNNETEKAFSNRYWDSFEAGIYVDVVTGEP
                     LFSSKDKFESGCGWPSFSRPISPDVLRYKTDKSFNMNRTEVRSRSGNSHLGHVFTDGP
                     KDQGGLRYCINSLSIRFIPKAEMEAKGYGYLLTAVD"
     gene            12073..12813
                     /locus_tag="TV188_001115"
     CDS             12073..12813
                     /locus_tag="TV188_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1534479.1"
                     /translation="MYSLLIVEDEYLVRQGIRSLVDFDQFAIDRIAEAENGQVAWELF
                     QENPYDIVLTDINMPKLNGIQLAELIKARAPKTHLVFLTGYDDFNYALSALKLGADDY
                     LLKPFSKSDVEEMLKKLKQKLEKLKKTEALQKLVDKPQQEGSEIKLAIQERLADSSLT
                     LKSLSSQLGFSPNYLSVLIKKDLGLPFQDYLIQERLKKAKLLLLTTDLKVYEIAEQVG
                     FEDINYFSQRFKQLVGMTPRQYKKGEGQ"
     gene            12810..14528
                     /locus_tag="TV188_001116"
     CDS             12810..14528
                     /locus_tag="TV188_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1534480.1"
                     /translation="MKRYPLLVQLVSYFFLIVISLITILGVIYYQTSSHNIRQLIERE
                     TRQSIRQSSQFIDAYIKPLKETTSALASHAEIQSFAKAANSSHQEQVLALMTTVLSTN
                     SDLRSAVLVTKDGRMVTTNPKLIMTTSHDMMAEPWYKSAIDRKAMPVLTPARQLSSHS
                     KKDWVVSVTQEVVDETGNNLGVLRLDIGYNTIKSSLDQLQLGRRGFAFIVNDKHEFVY
                     HPKNTVYSSEREMAAMKPYLAVADGYTKPKDYFVYQRVIPDSQWTLIGVASLDQLYHV
                     QRQIFWSFLGTGLLATVICGLGTVFVLRSWIGPIRRLQALILAIQKGNRQLRAEEIGS
                     PELADLARQFNAMLDQIDSLMISVADKEKAIGQYRLQALASQINPHFLYNTLDTIIWM
                     AEFNDSQRVVDVTKSLAKYFRLALNQGNELISLADELDHARQYLFIQKQRYGDKLHYE
                     IKGLEKYQDFMIPKLILQPLVENAIYHGIKEVDRPGMIRVTVLEADRHVILSVWDNGK
                     GISLADDSSQALLECGGVGLKNVDQRLKLQYGHLYRMAITSEQAVFTEIKLYLPKPLD
                     GLNELP"
     gene            14567..15655
                     /locus_tag="TV188_001117"
     CDS             14567..15655
                     /locus_tag="TV188_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEL1534481.1"
                     /translation="MSLESDYFKRKSPVFEALIPYGFTQEGDTYCYQESFMEGDFKAL
                     ITIKSSGQLSARVIDTDLGEDYLPLRNDRQQGVYVGQVRQAYLELLGRLSAACFRSTP
                     FQTRQANQVATSISQQWNDPLDYPFEKFPNIATYRVSGKWYAMVLPLLADKLGQVPKV
                     LQGQMVEVLTVRIAPNQLTHLLQQRGVYPAYHMSKKTWISLLLDGTLADDQLWELVTK
                     SRQLANPNGLANPDGPDYWVIPANLSYYDIDAEFAANPDILWTQKASIKAGDYVFIYI
                     TAPTRSIRYACQVLRSDIPNQGYRKNAKIKTLMSLRLLHCYEDGLISLDLMKQYGVNA
                     VRGPRRLSPQLVAFLKEKEYFKDVKQKE"
     gene            15670..16374
                     /locus_tag="TV188_001118"
     CDS             15670..16374
                     /locus_tag="TV188_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HEL1534482.1"
                     /translation="MTQFIADQSFWELFPDAKLGVLLLRNYDNQEDSPQEVKQLLADS
                     HDIAKQYLTEESFSDNEIIQVYRQAYQRFKTKKGARSSIEALLKRVANGQVLSSINPL
                     VDIYNTASLRFGLPVGAEDSDCFVGDLRLTLTEGGDEFYLIGDSKNSPTLPNELCYKD
                     DAGAVCRCLNWRDGERTMITDRTKNAFLVIEALDSKTQARLQDALKFIEDKAKCYLKA
                     ETALYTLDQASPSITF"
     gene            16634..17122
                     /locus_tag="TV188_001119"
     CDS             16634..17122
                     /locus_tag="TV188_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003032586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HEL1534483.1"
                     /translation="MELFDKVDDTLKALAIDYQLVEHEPALTTEQADQFIEGIEGVRT
                     KTMFLTTRKKNHFYLIIMDDTKRLDMNRFKELVGEKQIKMASAECLLAKMQLPPGVVS
                     PFGLLNNEDKDIQVYVDKAIAHEARMSFHPNTNDKTIFIQTDDLFKFLAAIGYAVNIV
                     DL"
     gene            complement(17632..18105)
                     /locus_tag="TV188_001120"
     CDS             complement(17632..18105)
                     /locus_tag="TV188_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEL1534484.1"
                     /translation="MNKKETRHQLIRSLISETTIHTQQELQERLRKNGISITQATLSR
                     DMKELNLVKVTTGNDTHYEALAISQTRWEHRLRFYMEDALVMLRVVQHQIILKTLPGL
                     AQSFGSILDAMQISEIVATICGDDTCLIICEDNEQAKACFEILSHYTPPFFFSNK"
     gene            18246..18926
                     /locus_tag="TV188_001121"
     CDS             18246..18926
                     /locus_tag="TV188_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HEL1534485.1"
                     /translation="MIRREDYQYLRKLDDFCHFSIEQFDKIVGQMEFRQAKKDHMLFF
                     EGDKRDRLFLVTSGYFKIEQSDRTGTFTYTDFIRHGTIFPYGGLFTDDYYHFSVVAMT
                     DVTYFYFPTDLFEDYSLHNQQQMKHLYSKMSSLLELHELKVRNLITSSASSRVIQSLA
                     ILLVEMGKDSDTLPFQLTTTDIAQMSGTTRETVSHVFRDLKKEGLIAVKGKYLTYLDK
                     NYFLQYTT"
     gene            19195..20430
                     /gene="arcA"
                     /locus_tag="TV188_001122"
     CDS             19195..20430
                     /gene="arcA"
                     /locus_tag="TV188_001122"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEL1534486.1"
                     /translation="MTAQTPIHVYSEIGKLKKVLLHRPGKEIENLMPDYLERLLFDDI
                     PFLEDAQKEHDAFAQALRDEGVEVLYLETLAAESLVTPEIREAFIDEYLSEANIRGRA
                     TKKAIRELLMSIEDNQELIEKTMAGVQKSELPEIPAAEKGLTDLVESSYPFAIDPMPN
                     LYFTRDPFATIGTGVSLNHMFSETRNRETIYGKYIFTHHPIYGGGKVPMVYDRNETTR
                     IEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKQNLGFKKVLAFEFANNRKFMHL
                     DTVFTMVDYDKFTIHPEIEGDLRVYSVTYENEELRIVEETGDLAELLAANLGVERVEL
                     IRCGGDNLVAAGREQWNDGSNTLTIAPGVVVVYNRNTITNAILESKGLKLIKIHGSEL
                     VRGRGGPRCMSMPFEREDI"
     gene            20440..20871
                     /locus_tag="TV188_001123"
     CDS             20440..20871
                     /locus_tag="TV188_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1534487.1"
                     /translation="MTRVIVGNQPFQRAASLYIRYQVFVLERQIDRQDEFDCFDDNDR
                     VYAVLYDGDQPVSTARFLPTAKDQARLTRVATLRQYRGRGYGAQVIEALEQYAREQAY
                     ERLVIHSEISAQSFYEGLGYQAFGEPYDEDGEPCQSVEKYL"
     gene            20886..21899
                     /gene="argF"
                     /locus_tag="TV188_001124"
     CDS             20886..21899
                     /gene="argF"
                     /locus_tag="TV188_001124"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEL1534488.1"
                     /translation="MTQVFQGRSFLAEKDFTREEFEYLIDFAAHLKDLKKRGIPHHYL
                     EGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVKENFGKLEGLTLVY
                     CGDGRNNVANSLLVAGTLLGVNVHIFSPKELFPAEDIVKLAEGYAKASGAHVLVTDNA
                     DEAVKGADVLYTDVWVSMGEEDKFEERVKLLKPYQVNMELVKKAANDNLIFLHCLPAF
                     HDTNTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLFI
                     PKV"
     gene            22061..23554
                     /locus_tag="TV188_001125"
     CDS             22061..23554
                     /locus_tag="TV188_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEL1534489.1"
                     /translation="MTEEKKRGFKIPSSYTVLFIIIAIMAVLTWFIPAGAYETAKDGG
                     VISGTYQTVKSNPQGFFDILMAPVRGMLGVKGTEGAIQVSFFILMVGGFLRVVNKTGA
                     LDTGIASVVRKNKGREKLLIAILIPLFALGGTTYGMGEETMAFYPLLIPVMIAVGFDS
                     IVAVAIILIGSQIGCLASTINPFATGVAADAAGVSIADGMIWRIIQWVVLVGMSIWFV
                     YSYASKIEKDPSKSLVADKAEEHKEFFQLQNSGEDLTSRQRKVLAIFTLTFVIMILSL
                     IPWEDFDIQLFTNINTWLTTTPVLGGIIGKTMGAFGTWYFPEITMLFIMMGVLVAVVY
                     RMSEDDFFSAFLSGAGEFLGVAIICAVARGIQVIMNGGMITATILHWGETGLAGLSSQ
                     VFVVLAYIFYLPMSFLIPSTSGLAGATMGIMAPLGQFSNVPAHLVITAFQSASGILNM
                     ISPTSAIVMGALALGRIDLGTWWKFIGKFIVMVMLVSVLLLVVATFF"
     gene            23571..24902
                     /locus_tag="TV188_001126"
     CDS             23571..24902
                     /locus_tag="TV188_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEL1534490.1"
                     /translation="METYIQPRHQEACVAAIKKIVSYPSVLNEGENDTPFGQAIQDVL
                     EATLALCQDLGFNTYIDPKGYYGYAELGDQTEVLAILCHLDVVPAGDLKLWHKDPFTC
                     IEKDGCLYGRGTQDDKGPSMMALFATKALMDAGVVFNKRIRFIFGTDEETLWRCMNRY
                     NEVEEEATFGFAPDSSFPLTYAEKGLLQAKLVGKGSPKLNLEVGQAYNVVPARASYQG
                     DKLEALKEELDRLGFEYVVKDDELTVYGLAQHAKDAPDGINALIRLAKALVVLEPEPV
                     LDFLAHVVDEDGRAVNIFGPVQDEPSGGLSFNVAGLTLTKEMTEIRLDIRIPVLADKD
                     TLVDQLSQKAQDYGLAYEEFDYLAPLYVPLDSELVTTLLEVYRKKTGDQSPAQSSGGA
                     TFARTMANCVAFGALFPDAVQTEHQENEHIVLADAYRAMDIYAEAIYRLTR"
     gene            24920..25870
                     /gene="arcC"
                     /locus_tag="TV188_001127"
     CDS             24920..25870
                     /gene="arcC"
                     /locus_tag="TV188_001127"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEL1534491.1"
                     /translation="MTKQKIVVALGGNAILSTDASAKAQQEALVSTSKSLVKLIKEGH
                     EVIITHGNGPQVGNLLLQQAAADSEKNPAMPLDTCVAMTEGSIGFWLVNALDNELQAQ
                     GITKEVAAVVTQVIVDENDPAFKNPTKPIGPFLTEEDAKKQMAESGASFKEDAGRGWR
                     KVVPSPKPIGIKEANVIRSLVDSGVVVVSAGGGGVPVVKDPASKTLTGVEAVIDKDFA
                     SQTLSELVDADLFIVLTGVDNVYVNFNKPDQRKLEEVTVSQMKEYIAQDQFAPGSMLP
                     KVEAAIAFVENKSNAKAIITSLENIDNVLSANAGTQIIAG"
BASE COUNT         7435 a         4919 c         6049 g         7577 t
ORIGIN      
        1 tcaggggggt gagaaaaaag acattagcta catcgagcaa gagggcgatc tgtctgccct
       61 atttcaatca gagacagact taagcattaa aaagaaacag cagcatcgaa aagaaactag
      121 tcagacgacc aagaatcacc tatttatgac tcatattgat agtgacaacc ttgttgcaag
      181 gtatcagcca ctcttattta acccagagca gcgtctggca gcaacagatg accagtatgg
      241 tgttttgctc gctcaaaaaa ctatcggcat cacttggcaa atgctggcca tacttcttgt
      301 gggagctgta ctgactggct attctctgac tagagggcga ttatcaaggc aaaaacacaa
      361 aagacatcac gagtagaatc gtctgtcaag agtatctact cactgaaaat agagggctag
      421 cttaggagac ttcctaatgc tgcatttata agaaaaggct ctcagctgtt ttgacagtat
      481 tgggcaaggc cttagggcct gtagcaaata tgaagagcag ctttgatcag caggtagcaa
      541 gtcagtcaat acaaatgctt gaaagcctac ctgctgagaa aagtgtgtgt tctacgatac
      601 tttagtgatg tgaatcacct caagaggctt tagctagctt ggcaggtgat gtcaggtgac
      661 atggaaactt atcaggaaag ggctaatttt tatggagaat tatattagta tcagtcttga
      721 ttgctcgcat ttttttcaca ggaatttgat ttgcgggtac caaggacaat gacctttaag
      781 gagctattac aaatcgtatc agatgcttat ggtttgggat ttcaggtggt aaatcccagt
      841 gctagaaatg agcaaggtgg tcagctgatg acaagcacca gtcgcatgga taccctaaaa
      901 aatggtgcac tgttagtatt ggaaaattta taaacatgga gaaaaagatg aaaacaataa
      961 tacgtgagct attggttgag gatgttaaag gagatgctga ggttgcttat accttactag
     1021 cttctgagca ttctcttttt gttccttcca agttagaaca ggctttcgac aagctgattc
     1081 tagaggctag cattgatgac atgtatgact ggtcagccct agaggcgatg attgttgagg
     1141 aaaagctaag gcatttgcta aatcttagtg agctgtttga tcagctcttg gactcaaagt
     1201 tcacctacag ctttacacca gataatctgg tctttaaccg taatgcagag ccacagttga
     1261 tttttcgggg aatcaaggat caggttcctc cttaccagcc gcttgagcgt gaggtctttg
     1321 tgaatacact gaaatgtatg acaattgcct tgcttgataa aaagaccagc tatgacgctc
     1381 tgatgggtgg caagcttccc ttttacaaag gcaatctttt ttgcgaagca gtggccaagg
     1441 ctgaggcgct gcaggagttg caggagcttt tagcgacaaa gtaccatgag gagcaaaaag
     1501 acaataaaga gcatttttct cgtgttgcta acaagacgat atcgcgcttg aaattgacca
     1561 ccatttgttc atcagtgctt gctttgttgt ctttggcggg cgttctttat tttctattgt
     1621 ttgctatgcc ttatcaggaa atggttgcta gtctgcgtat ggcttttatt aatcaagact
     1681 attctaaggt tatcacaaca gcgaagcata cagacagtaa ggccttaagc cagggtgata
     1741 aatatattgt ggcttactct gtcataatga cagagcctct aacagacaag caaaaggagg
     1801 aattaagtaa aatatcgaac cagtctaatg aagattattt acgctattgg gtgctgattg
     1861 gtcaagcaag gatagatgat gccatggata ttgcgagcta tctagacgac ccgcagctct
     1921 tgatgtatgg cttgactaag aagattgatg atgttcagcg agatcctaat ctgacagcag
     1981 aggcgcgtac agagcagctt aacagctata agagcaaatt agacgagctc aaaaaggcct
     2041 acctgacgcc taaagaggaa aaagcagcag gctctagcag tgacaaggag tgacggagga
     2101 atttatgaca taccttattt atgacgacaa tgcctatcac ctttattcgg ataccgttta
     2161 tcagttgggg ccttcatcag ggtctgatat tttcctgccc ttgctggagg atattacctt
     2221 atcagtggag ggatcaggtg ttgtcctact ggaagagagc tacagcactg gtaagcattg
     2281 tgttgctctt tctgatgagg ttacagtgac cttacttatt cttgaagctg tcactaaata
     2341 cctgctgcca gactcctcgc tttacatttc aggagagact accgcagcac ttcaattgct
     2401 tgattaccct agtgagctgg tgctgaccct agactctgat tctgccagct gctatagccc
     2461 ggtgtcttat tatctaaatg gtaaatggac gaaaggcaag cagcctctta aagcatctga
     2521 tgaacttgtt ttttcagatg gcttagtgct tagttttcag gatcagctgc tatcgattca
     2581 gtccttgtat gctattcaga cagcattgct gcctcttaca gaggcagtag ctgaggatag
     2641 agccagtgaa tttcatcgtt ctcctaggat tatcctgcgt gagcctgagg gaaaggtgac
     2701 gattgcttct gtacccacag atgatgaagg gaaaagacag tctttattaa agctgatcat
     2761 aacgcccctt gcgatgattg tctttacagg gctctcttat gtctttttcc gaggtggggg
     2821 aatgctcatg atgatgatgg gaatgtctgt gattacgatt ggaagctcca ttcattctta
     2881 tttttcagat aaaaaatggc ataaagaagc ccagcagcaa aaaatcaagg attatctagc
     2941 ctacttggat accaagtatg tggagctagc aggctatcgt gaggagcaaa tcgaagcact
     3001 gctgtatcat taccctaata tgacgactat tcttgaaatg gcacaaaaaa cagatcgccg
     3061 tatttatgag aaggctccat atcattttga ctttttgacc taccgcttgg ggctaggtga
     3121 tactccagcc agctttcaca ttgattattc agattctgag ctgaccaagc atcatgaaaa
     3181 ggcaaagcaa agggttcaag agctgattgc ttattatcag gtgacagcac aggtgcctat
     3241 ccaaaatgcg attgccagtc caatcggtta tattggagca cgcaaggtcg tgattgagca
     3301 ggttcagcag ctgatgatgc agatcgctac cttccatagc tatcatgatg tacagtttat
     3361 tcctattttt cgagaagaag agctgccatt gtggaattgg agccggtggc tgcctcatac
     3421 taagctaaag gtgctaaata gtcgtggctt tgtttatagt cagcgaacac gtgaccaatt
     3481 gttgacctcg ctttatcagc tgatcaagga gcggcaatta gacagtgagc aggataaggg
     3541 gacagaaaag caatacactc cgcattatat agtgctgatt actgacatga gcctcatgct
     3601 tgaccacaat atcatggaat acatcaatga ggatttgtct catctaggca ttcattatat
     3661 ttttgttgaa gaggtcattg aaagtctccc tgagcatgtc aaaacagtta ttgattatcg
     3721 tggagataag catgctcagc tcattttgca ggaggggctc tacctcaata aggcctttac
     3781 cccacttcaa cccttatcta tgaaggataa ggaggtcttt gctagacata tggcagggat
     3841 taatcacgtt gagaccttac gcaatgcgat tccaaatagt gtgacctttc ttgaaatgta
     3901 tggcgttaac aaggtcgagg agcttaatct cttaaagcgc tggaaggaaa atgaggctta
     3961 tcagacaatg gctgttccgc ttggggtgcg tggtcgtgat gacatcttgt acctaaacct
     4021 tcatgaaaaa gcccatggac cgcatggctt aattgcagga acgactggat ctggtaaatc
     4081 agagctggtt cagtcttata ttttgtcgct ggcggtgaat tatcacccct atgaggttgc
     4141 ctttttgctg attgactaca agggtggtgg tatggccaat ctctttgctg atttaccaca
     4201 tgtcgttgga accattacca acctagatgg caatcaggcc aatagggctt tggtatcgat
     4261 taaggcagag ctgaaaaagc gtcagcggat tttccttgaa aatgatgtca atcatattga
     4321 tcaatacact aagctattca aggaaggacg agttaaggag cccctcccac acctgttaat
     4381 catcagcgat gaatttgcag aattaaaggc caatcagcca gaatttatgg acgagctggt
     4441 ctcaaccgcc cgtattggtc gttctcttgg tgttaagctc attttagcaa cgcaaaagcc
     4501 aagtggtgtc gttaatgacc agatttggtc gaatgcgaag tttaaaattg ccttgaaggt
     4561 tcaagatgtt gcagattctc gtgaggtgat taaaacccca gatgcagcag agattactca
     4621 ggttggtcgt gcttatctcc aggttggaaa caatgaaatt tacgagctgt tccaaagtgc
     4681 ctggtctgga gcagactaca atccaaaagg acgacatacc attcagcatg agacaacggt
     4741 ctatgaaatc acagctaatg gtcaatacca agcgattaac aaggacctta gtggacttga
     4801 caagaagaga gaagcaaaat ccatgccaac agagctagat gcggttgtag cagaggctca
     4861 gcagctcttt gaggacctgc atattccaaa ggtggccagt ccttggctgc cgcccctttc
     4921 agaaaaaatc tatgccagtg atttacagtc cacgcatttc aaggactatt ggggacagac
     4981 acaggacttg cagcctgttt tgattggcta tcaggacatt cctgaacgcc aagagcagtc
     5041 cccactctat tttcatatgg aaaaggctgg gcatatcctc ttagtgtcta gtcctggctt
     5101 tgggaagtcc accttccttc aaggctttgc tttagatgtg atgcgaaagc aaacaccagc
     5161 acaggctcat ttttacctct atgattttgg gacaagtggc ttgattgcgc tttctgattt
     5221 tccacatgtg gcagattact ttaccctaga tgagacagac aagatcatga aatcacttcg
     5281 ttatttaagt gaagaaatca agacccgtaa gcatgcccta tctaaggcta aggcaaccaa
     5341 cctcaatcag tacaatcaat tatccaagga taccttcccg gctctttttg tcatcattga
     5401 tggctttgat agtgtcatgg acgcaccatt tgtagatgct gtctacaatg tcttaaacgt
     5461 tattgcgcgt gatggggctt ccttgggaat gtaccttgtt gtgaccttat caagacttaa
     5521 taccatgagg ctacagctgc agtctaactt taagaccaag ctatccctct tcttgtttga
     5581 taatagtgat ttatcaagtg tggttggtcg ctcaaatatc ccactagatg atatcaaggg
     5641 acgagctatc atgaaacgtg acgacattat ccaatttcag attgccttgc catatagcag
     5701 tgagtactat acagattata tggcggaggt aaaaagagag gtcgaggcga tgagggctgt
     5761 ttatcaaggt gctttgccag cggctattcc aatgctgcca gaaaaggtta caccggatat
     5821 gatagcagcc atgtcagact ctgctcagga ttttgtgatt ggtttggagc gagaggacgt
     5881 tgttcctgct ggctttacct ttaaaaagtc aatactgatg gcctctgata gcccagcctt
     5941 tgtggctaac tattataagc tgcttgattt tcagttgcag cgtctggctg accagtatcg
     6001 tacggttatt ttagatccta gtcagcgtat tgcaaggcaa ttctttgagg atagtcaacg
     6061 ctttagcaca gccttagatg ttggagacac tctaagggct attgtagagg actttaaaaa
     6121 gcgtcttgca gcacctggtc aggattatca aaaatggtta gttgtgattc ctgatattgc
     6181 agctacagcg ctggcagcag ggattagcga ggaagacttt aaacagcttg tgaccgaggg
     6241 cagccagtat ggggtcacgc ttatctttgt cggagcttat caggatctgg tcaataatac
     6301 ctatgataat tttgtgaagc ttgcaaatca gctcattgag caggtctttt taggcatgcg
     6361 gatcagtgac caaagccata cacgatatgc ttatatcagc aatgagcctt cacttagacc
     6421 gacccagggc tatatcctat acccagaagg ctatgacttt attcaattat tagagattta
     6481 gaaaggaaca aagatgtcaa cagttacgat gcttccactt ggtagtattg tcattttaaa
     6541 gggcaatact aagaaaatga tgattattgc gcgtgtgatc gcagctccaa tcaaagggga
     6601 ggtttaccgc tttgactatg gtgcctgcct gtatccggag ggcatgatgg gggatagttt
     6661 gatttacttt aatcatgacg atatttttaa gattattcaa gaaggctatg ctgatgatga
     6721 caatgctctg atgttagaga cgatagcaca ggctttagca acaacggaca ttccaaaagg
     6781 agatgtttca gccttaaacg atagaaagac tgttgaggac tagcttatgg ggcaagttga
     6841 ctacaatcat atcaatcagc ttcaacgtca ggttgaccag cacagggcca gtctatcaac
     6901 ggctacagca gagatagcgt caatagacga aaagctagag cgcttgcgtt gtgccaaggc
     6961 ttctgttgga gcgattcaag gagatgttca tcagatcaag gtctctgtga tggctaagag
     7021 ggatcagcct gattggaagg gagaacgcaa ggaccgcttg atgtcgagct gggaggagtt
     7081 ctctcatgac tatcgccact ttcagctgga gctagatgct tattacgatg ccatttgtga
     7141 tacgataaca cgcttggaga atcaaaaata tgagcagcaa gggcttatcg gctggtgtca
     7201 gagcatgatt aatagcttgg gaaatgagat tgaaaagcta tttcatatta gggagggcta
     7261 gcatgtttgg tgttattcaa ttatctgagg ttgtgtttgg ggcgcatgtg ttaagcctga
     7321 ctgctgctaa ggctagcttg tctgatgtca aagctagctt tcccagccat cagtcatcaa
     7381 gtaaggtgct agatctgtat cagtcagagt ttgaagcact ctctcagctt gttgctgcct
     7441 atgctaggct tttggaaaag gatattgcct tgattgccga ggctggtcaa gaattagccc
     7501 taacagataa gcagttggga caagctatag gatttaggtt acaataggag gagggtatgg
     7561 gatataagat tcactttgaa gccatcagtg ccgcccaaca aagcactcaa accacgatca
     7621 gtgcttgggg agaaaggtcg tcttctcttt tatgatgttc aaagcaaggt aaatactttt
     7681 cttgaagttg tcaacgtttc tgaatccaaa agcattgcgc ttgatacctt tgataaattt
     7741 gttagttgct tcaagcttgg cgttagaata aggcagttca atggcattga tgatatagtc
     7801 gttatagcgt ataaaggtgt ttaaagtcgt tttgaaggtg tgattgagat gaggcaaagc
     7861 atcttgactt aacccaaaga agagctctgt cttcttttct tgcaagtgaa aaagaagtca
     7921 ttggtacaga tcataatagc cttttaactc agggattcgt ttgaaaatct tattgagaca
     7981 ttgtctagga gttaatgttt ctctaaaggt cctagagtag aaagtattaa gagatagttt
     8041 ccagttatcc tttagactaa gcttccaata gtatttaaga gcccgatatt caagagcttt
     8101 cttatcaaat ggcttcatga gttgaatgcg agtttgattg agcgctctac tcatgtgcta
     8161 cacaatgtgg aagcgatcga gaacaatttt agcttttggg agtgaactag tccagtggac
     8221 taattcagcc tgagcttaaa aatagaagag cgaagggttt aatgagagga atgtaacttc
     8281 ctgacatatc gacagtaaca actttgccct tatttctagc ttctttggag tacttaaaga
     8341 agtgatttcg aatggttgtt tgacatctgt tattgcgaat gataatgatt ttcttggtgt
     8401 tgaaatcctg agcgataaag gctagtttgc ccttttgata agagaattcg ttccaggaaa
     8461 gcacctcagg taaggtggtg taatcctctt taaagtgaca ttgcttgagc ttatgataga
     8521 cggtagaggt agagatagcg agtttagcag caatatgcgt aaaagcttct ttattgagca
     8581 atagctgaga gatcttctgt ctaactggtt cagagatttg gcaatttttc ttcacgagat
     8641 tggtttcaga gacagctacc ttccgacagg tttgacattg aaacctgctc tttttcaatc
     8701 gaataaggct agggaagcca ccgatttcga tgaaagggat tttagagggc ttctggaagt
     8761 catacttaat ctgagctctc ttacagtgct tacacttagg aggttgatag tccaatgtag
     8821 cgatgacttc gatatgtgta tcatgctgga tagccttatc gaaggtgata ttttgatctt
     8881 taattccgat gagtagtgtg gtatgatgaa tctgttccat aagacacttt ctaatgatgg
     8941 tctggtcgct tttcatgata agccttatgg gactttttgt gtactcaaaa gccctataat
     9001 ctccatagtg gacttaccca ctacagaaat tataaagccc taaaaaccaa tctgaggttg
     9061 ttgcaacagg attggttttt tcttgtgatt gcagatcaga cttttcaaaa gaacaagcac
     9121 attatctcag ctagactggt gcttgatagc tcctgagccc ttgtttgctg tagttgatag
     9181 gactttgctg atggcctagt caggcatatc gtatcaaatt caagtttttt catgtcactg
     9241 tctatagttt gtctgcccta ctttaggtag aatagaggta acttaagaga ggagtttatt
     9301 atggaattaa cgatgctttt gatggtttca gttttcattg cagggctgtt atcattcttt
     9361 tccccttgta tctttccagt tctgccggtg tatttaggca ttttgttaga ttctgatgat
     9421 tctaggtcta ttactatttt tggcaagaaa ctatattggt acggtattgt taagaccctt
     9481 gcttttattt caggtctatc taccattttt atcattttag gctatggggc tggtttactg
     9541 ggtaatattt tatatgctgc ttggtttcgc tacctacttg gtgcctttgt gattttgtta
     9601 ggtattcatc aaatggaaat cgtaaccatt aagaagctgc aatttcaaaa gagcgtagca
     9661 tttcaaaata agaaggaccg caatgctgtt ttaaatgcct ttttgctggg aattaccttt
     9721 agctttggtt ggacgccctg tgttggacca gttcttagct cggtgcttgc cttagcggct
     9781 tcaggtggca gtggggcttg gcagggtggc ttcttgatga ttatttatac cttgggctta
     9841 ggcctaccat ttttactact atcttttgct tctggtattg tgttgaagca ctttaataaa
     9901 ttaaaaccac acattcctct attgaagaag ttaggtggct tacttattgt tataatgggc
     9961 ttactgttga tgacaggaaa tctcaatagt ttatcaggtt tatttgaata aaggagaaga
    10021 aacaatgaaa aaaacaacat ttttaacaac aggcttagca tgtcttgctt tattaactgc
    10081 atgttcggcg aaggataaaa tggccatgaa tgatagtaaa aaagaccata tgaccaggac
    10141 cgatgacaaa tcaaagatga aaaaggatca aaaagacaag atgtcagaca agaaggatat
    10201 gatgtcagat gacaagcaca tgtcagatgc tgacaaggct agtaagaatg atgggcaaat
    10261 ggctccagat tttgaattaa agagcattga tggcaagact tatcgtttgt cagattttaa
    10321 aggtaagaag gtttacttga aattttgggc ctcatggtgt tctatctgct tatcaacctt
    10381 aggtgataca cagtcattag ctacgatgaa ggataaggat tttgaggtct taaccattgt
    10441 ttcacctggt catcagggtg aaaaatccga ggctgatttc aaaaaatggt ttgaaggaac
    10501 agactttaag gatttaccag tcttgctcga tccagatggc aagctgctag aggcttatgg
    10561 tgtgagatct tatccaactg aaatttttgt tggcagtgat ggtgttttag ctaagaagca
    10621 tattggttat gcaaagaaat cagagattga aaaaacctta aaggagatta aataagcaaa
    10681 ggaggctgtc tcatggaaca caaatggaag ttattgctac tcgtttttgg agccttagta
    10741 tttttaggag gtgttttgat ggtctttcaa agaggctacg ctactagcta ccataataat
    10801 caggtcaagc tgcctgccaa agggacgtct cagctcaaga agactgctaa tgccaagctg
    10861 cctgagaaga aaaaggagat ttaccttgca ggaggctgtt tctggggtgt ggaggagtat
    10921 ttttcaaatg ttgatggtgt tctagatgct gtttctggct atgctaatgg tagaggcgac
    10981 acaacctctt atcaattgct gcaccagaca ggacatgctg agacggttca ggttgtgtat
    11041 gatgctaatc ggattagctt aaaggagctt cttttacact actttagaat cattgaccca
    11101 acaagcctca ataagcaggg caatgatcgt ggcagtcagt accgtacagg catttattat
    11161 acggatccat ctgatttgac tactattgat atggtctttc aggaaaaagc ttcggattac
    11221 aaaaagaaaa ttgttgtgga aaaagctccc ctaaagagct ttaccaaggc tgaggaatat
    11281 catcaggatt acctcaagaa aaatcctaat ggctactgcc atattaatgt caacgaggct
    11341 tcatacccag tgattgataa gacaaaatac cctaagccaa gtaaggaaga gattaaaaag
    11401 aagctatcaa aggatgaata tcgtgtgacc caaaacaatg aaactgaaaa agccttttca
    11461 aacaggtact gggattcctt tgaagcaggg atctatgtag atgtggtcac tggtgagccg
    11521 ctgttttctt ccaaggataa atttgaatca ggctgtggct ggccaagctt tagcaggcct
    11581 attagcccag atgtgctacg ctataagaca gacaagagct tcaatatgaa ccgtacagag
    11641 gtgagaagcc gctcaggcaa ttcccattta ggtcatgtct ttaccgatgg tcctaaggat
    11701 cagggtggtc tgcgttattg tattaacagt ttatccattc gatttattcc aaaggctgaa
    11761 atggaagcta aaggctatgg ttacctttta acagcagttg attagaagat tatcctaaga
    11821 tttgttataa taagatgagg aagcacagat ggttgattat agttattaag acctgaagat
    11881 tacttcagtc gatattgcta aatgtgatca ggctcatgcc ctttagtctt gcttaagagg
    11941 tagtagcttt taaaagagtg attacgataa gaggcatttg ctcagagctt gtcctattta
    12001 gctcttgtcg agctatgtgc agagcttgta tgactatggt cactaagcat tagaaatagt
    12061 aggagaaatg gtgtgtactc attacttatt gttgaagacg aataccttgt gcgtcagggt
    12121 attcgttctt tggttgattt tgaccaattt gccatcgatc gtatagcaga ggctgagaat
    12181 ggtcaggtgg cttgggagtt gttccaagaa aatccttatg acattgtttt aacagatatt
    12241 aatatgccaa agcttaacgg cattcaactg gcagagctta taaaggcaag ggctccaaag
    12301 actcatcttg tttttttgac aggttatgat gatttcaatt atgccctatc tgccttaaag
    12361 ctaggggctg atgactacct gctaaagcca ttttccaaat cagatgttga agaaatgctc
    12421 aaaaagctaa agcagaaatt agaaaagctc aaaaaaacag aggcccttca aaaactagtt
    12481 gataagccgc agcaagaagg ctcagaaatt aagctagcta tccaagagcg tttagctgat
    12541 tcaagcctaa cgctaaagag cctatcaagc cagttaggct ttagccctaa ctatctaagt
    12601 gttttaatca aaaaggatct aggtttgcct tttcaggatt acttgattca ggagcgtctt
    12661 aaaaaggcta agctcttatt attaacaacg gatttgaagg tttatgagat agcagagcag
    12721 gttggctttg aggatattaa ttatttttcc cagcgcttta agcagttggt tggaatgaca
    12781 ccaaggcaat ataaaaaagg agaaggccaa tgaagcgcta ccctctttta gtacaattag
    12841 tgagttattt ttttctgatt gtgatttcac taatcactat tctgggagtg atttattatc
    12901 agaccagctc tcataatatc aggcagctca ttgaacgcga aaccagacag agcattcggc
    12961 agagctctca atttattgat gcctacatta agccattaaa ggagacaacc tcagccttag
    13021 ctagccatgc tgagattcag agctttgcta aggcagctaa cagtagtcat caagagcagg
    13081 tgttggcact gatgacaact gtgctgtcga ccaattcaga cctgcgctca gcggttctgg
    13141 tgacaaagga tggtcgtatg gtcacaacca acccaaagct aatcatgact acctcgcatg
    13201 atatgatggc agagccctgg tacaagtcag ctattgaccg caaggccatg ccggtgttga
    13261 cccctgcaag gcagctgtcc tcgcattcta aaaaggattg ggtggtttca gttactcagg
    13321 aggtagttga tgagacaggg aacaatttag gggtgctgcg attggatatt ggctacaata
    13381 ccatcaaatc ctccctagat caattgcagc ttgggcgtag gggctttgcc tttatcgtca
    13441 atgataagca tgaatttgtc tatcacccta aaaataccgt ctatagctca gagcgagaaa
    13501 tggccgcaat gaagccttac cttgctgttg ctgatggcta tacaaagcct aaggattatt
    13561 ttgtttacca aagggtgatt ccagacagtc aatggacctt gattggagtt gcctctttgg
    13621 atcagctgta tcatgtgcag cggcagattt tttggtcctt tttagggacg ggtctgcttg
    13681 caactgtcat ctgtggtctt gggacagtat ttgttctgag aagctggatt ggtcctatca
    13741 ggaggcttca ggctctcatt ttagctattc aaaagggtaa ccgtcagctg cgtgctgagg
    13801 aaattggctc gcctgagtta gctgatttgg cacgtcagtt taacgccatg ctggatcaaa
    13861 ttgatagttt gatgatttca gttgctgaca aggaaaaggc tattgggcag tatcgtctgc
    13921 aagccttagc cagtcaaatt aatcctcatt ttttgtacaa caccttagat actattattt
    13981 ggatggcaga gtttaatgac agccagcgtg tagttgatgt caccaagtct ctggctaagt
    14041 atttccgctt ggccttaaat cagggaaatg aattgattag ccttgctgat gaattggatc
    14101 acgctcgtca gtatttgttt atccaaaagc agcgctatgg tgacaagctg cactatgaga
    14161 tcaaaggtct tgagaaatac caggacttta tgattcctaa gctgattctt cagcccttgg
    14221 ttgaaaacgc tatttatcat ggtattaagg aggttgatag acctggaatg atcagagtaa
    14281 ctgtattaga agctgatcgt catgtgatat tatccgtttg ggataatgga aagggcataa
    14341 gcttagctga tgacagcagt caggccctgc ttgagtgtgg cggtgttggt ttaaaaaatg
    14401 ttgaccagcg cttgaaatta cagtatggtc atctctatag aatggcaatc actagcgagc
    14461 aggctgtttt tactgagatt aagctttatc ttcccaagcc gcttgatggc ctaaatgagc
    14521 tcccctaatc aatctgccct tagtagaaca aggaaaagag aggtttatgt ctttagaatc
    14581 cgattatttt aagcgaaaaa gtcctgtatt tgaggccctt atcccttatg gctttaccca
    14641 agagggtgac acttattgtt atcaggagtc atttatggag ggagatttca aggccttgat
    14701 tacgatcaag tcgtctggtc agctctcagc tagagtgatt gatactgacc ttggggagga
    14761 ctatctcccc ttgagaaatg atagacagca gggagtttat gttggtcagg ttcgtcaagc
    14821 ttatctagag cttcttggac gtttatcagc tgcctgcttt aggtctaccc cttttcagac
    14881 aaggcaggcc aaccaagtgg caacaagcat tagccagcag tggaatgatc cactagatta
    14941 cccctttgaa aaattcccta atattgccac ttatcgtgtt tctggcaagt ggtatgcgat
    15001 ggtattgccc ctgctagccg ataaattagg acaggtgcca aaggtcttac aggggcaaat
    15061 ggttgaggta ttgactgtta gaattgctcc taatcagcta acacacctct tgcagcaacg
    15121 tggtgtttac ccagcctatc atatgtctaa aaagacctgg attagcctat tactagatgg
    15181 tacactagca gatgatcagc tctgggagct agtcacgaaa agtcgtcaat tggctaatcc
    15241 taatggccta gctaacccag atggaccaga ttactgggtg attcctgcta atctcagcta
    15301 ttacgatatt gacgcggaat ttgcagctaa tcctgacatt ctctggacgc aaaaggcttc
    15361 cataaaagct ggagactatg tttttattta tatcactgca ccgaccagat caattcgcta
    15421 tgcctgtcag gtcttgagat cagacattcc taatcaaggc tatcggaaaa atgcgaagat
    15481 taagacctta atgtcgctac gcttgttgca ttgctacgaa gatggtttga tttcccttga
    15541 tttgatgaaa cagtatgggg ttaatgctgt tcgcggtcca agacggttaa gcccacaatt
    15601 agttgcattt ttgaaggaaa aagagtattt taaagatgtg aaacaaaaag aatgataagg
    15661 agagcgggta tgactcaatt tatagcagat cagagctttt gggaattatt tcctgatgct
    15721 aagctaggtg ttttgttgct caggaactat gacaatcagg aagactcccc acaagaggtc
    15781 aagcaattat tggcagacag ccatgacata gctaagcagt atttgactga agagtcgttt
    15841 agtgacaatg agatcattca ggtctatcgt caagcctatc agcgttttaa gacaaaaaag
    15901 ggagccagat ccagtattga ggccctccta aagagggtgg caaatggtca agtcctatcc
    15961 tccattaacc ctctggtgga tatttacaat acagccagtc taaggtttgg tctgccagtt
    16021 ggcgcagaag atagtgattg ctttgtaggt gacttacgcc tgacgttaac agagggaggc
    16081 gatgagtttt acctcattgg tgattctaaa aacagtccaa ctctgccaaa tgagctctgc
    16141 tacaaggacg atgctggtgc tgtttgccgc tgcctaaact ggcgcgatgg tgaaaggaca
    16201 atgattaccg atcgcactaa aaatgccttt ttagtcattg aagcattaga tagcaagacc
    16261 caagcaagac tacaggacgc ccttaagttt atcgaagaca aggctaagtg ctacctgaag
    16321 gcagaaacag cactatatac gctggatcaa gcctcaccaa gtatcacgtt ttaatcaaaa
    16381 aaagctagga agccagtatt cctagttttt tcagttgttc aggtgctttt atttggtgtt
    16441 gtcgagggag atttccttat agctgcaaga tatgacatga cagggaaaca gtttttgctt
    16501 gtttgatcta atcaagcgat taataaaagc ttttaagctg ttggttatgc taaagggctt
    16561 tcttaatcct atcagagaac tttaaaaaat agtataatgt agttaactta tgatgatagc
    16621 taaggaggtc agcatggagt tatttgacaa ggttgatgat acgttaaagg ctttagcgat
    16681 tgactaccag ctggttgagc atgagccagc tttaaccaca gagcaggcag accagttcat
    16741 agagggcatt gaaggggtta gaaccaagac aatgttttta acgaccagga aaaagaacca
    16801 tttttatctg atcattatgg atgatactaa gagactggat atgaatcgct tcaaggagct
    16861 tgttggagaa aagcagatta aaatggcatc agcagaatgc ttgcttgcca agatgcagct
    16921 gccaccagga gttgtttctc cttttggtct tttaaacaac gaggataagg atattcaggt
    16981 ttacgttgat aaagctattg ctcacgaagc tagaatgagc tttcacccaa ataccaatga
    17041 caaaaccatc tttattcaaa cagatgacct ctttaagttt ctagcggcta taggttacgc
    17101 ggtcaatatc gtggatctat agctaaattc aaggttcttc tagcggttct tgctcacatc
    17161 agttcacaaa gctggtggcc tagccaatcc agggcaaaca aaaagcacaa tagcctttct
    17221 tgactactga gaatagccag tagacccttg tgtcatatgc ttatctggta tttgagctta
    17281 aatctcaagg cttttaagta gaggatcaaa caaagaaaac gaccagcaga ccttgcgtga
    17341 tgactgatta tcaagtctgg taggagctaa aatcagtcat ggtcttgagg cctaaaacgt
    17401 cccatttgtc gctcctgttg ctagggcatt agttgacatg tatacccacg actaaccaag
    17461 ccgaggagag ctgtcgctcc cttctcagga gcgtggattg aaatgcaaaa gggatctgat
    17521 agacatttct gcttttaaag ctagtccatc aaaaaaacgc atgacaccac tgtagtggga
    17581 catcatgcgt ttttgctaag ctaaagtgat ttgacgcttc ctttgaaagg gttatttatt
    17641 gctgaagaaa aagggtggtg tgtaatggct caggatttca aagcaagctt tggcctgctc
    17701 attgtcctca cagataatca gacaggtatc atcaccacag atagtggcta cgatttctga
    17761 gatttgcata gcatcaagga tagagccaaa ggattgtgcc agccctggta aggtttttaa
    17821 aataatctga tgctgaacaa ccctgagcat gacaagggcg tcctccatat aaaagcgcaa
    17881 acgatgctcc caacgcgtct gagaaatggc cagcgcttca taatgcgtgt cattaccagt
    17941 tgtaaccttg acaaggttaa gctctttcat atcacgtgat aaggttgcct gtgtgatgct
    18001 tatcccattt tttcgtaagc gttcctgtaa ttcctgctgt gtgtgaatag ttgtttcaga
    18061 aattagagat cgaattaatt gatgacgtgt ttctttttta ttcatttctt ataatattcc
    18121 cctaatgatt agtaacattc agagtataac aaaaagatgg cagtgtgtaa agttttagat
    18181 gaaccgctta caaaaatagc ctttttatgt taaaataaaa cgggtgctta gaaaaggaga
    18241 tttgcgtgat tcgaagagaa gattatcaat accttagaaa acttgatgat ttctgtcatt
    18301 tttcaattga acaatttgac aagattgtcg gccaaatgga atttagacaa gctaaaaagg
    18361 atcatatgtt attttttgaa ggtgataaga gggacagact ctttttagtg acctcaggtt
    18421 attttaagat tgagcagtca gatcggacag gaacctttac ctatactgat ttcatacgac
    18481 atgggacaat ttttccctac ggggggctgt ttacagatga ctactatcat ttttcggtgg
    18541 ttgcgatgac agatgtcacc tacttttatt tcccgactga tttgtttgag gactattcct
    18601 tgcacaatca gcagcagatg aagcatctct acagtaaaat gtcgtccttg ctggagcttc
    18661 atgagctcaa ggtgcgcaat ctcatcacct ccagtgcaag ctcacgtgtg attcaatcct
    18721 tggctatttt actggttgaa atgggaaagg atagcgatac tctgcctttt cagctgacga
    18781 ctactgacat tgcacaaatg agtggaacaa ccagagaaac cgttagtcat gtctttagag
    18841 atttgaaaaa ggaaggcttg attgcagtca aggggaaata cctcacctac ctagataaaa
    18901 actattttct gcagtacaca acctaagatc aagtcaaaag gcttcgctta aaaagttttt
    18961 tgactttttt caatttataa atataagatt tttcgttaaa atgtaaaaaa caaacaagaa
    19021 aacgtataca aaaacataaa cattcatttt caggcgaaaa agtgtaatcg tttacacaga
    19081 ttggctgtga gaaataccct atttttgaat gctgcttgga gtaaactagg ggtgtaagca
    19141 aaagctaaga gtcttagcag tgaattcaca aaacattaga aagaggtaat tcttatgact
    19201 gctcaaacac cgattcatgt ttactctgaa attggcaagc tgaaaaaggt tttgctccat
    19261 aggcctggca aggaaattga aaacctgatg ccagactact tggaacgtct attatttgac
    19321 gatattccat ttttggagga cgctcaaaaa gagcatgatg cttttgcaca agcattacga
    19381 gatgaaggcg tagaggtgct ataccttgaa acactagctg ctgaatcact tgtaacacca
    19441 gaaattcgtg aagccttcat tgatgaatac ctaagcgaag ctaatattcg tggaagggca
    19501 actaaaaaag ctattcgtga gctactgatg tctattgaag acaatcagga attgattgaa
    19561 aaaacaatgg caggtgtgca aaaatcagaa ttgcctgaga ttccagcagc agaaaaaggc
    19621 ttgactgact tggttgaatc aagctatcct tttgcgattg acccaatgcc aaacctttat
    19681 ttcacacgtg atccgtttgc aactattggt acaggtgttt cgcttaacca catgttctca
    19741 gaaacacgca atcgtgaaac aatctatggt aagtacattt tcacacatca cccaatctac
    19801 ggtggcggca aggtacctat ggtttatgac cgtaacgaaa ccactcgtat cgagggtgga
    19861 gatgagctgg ttctttcaaa agatgtgctt gcagtaggta tctcacagcg gacagacgca
    19921 gcatcaattg aaaagctctt ggttaacatc tttaaacaaa atcttggctt caagaaggtt
    19981 ttggcctttg aatttgctaa caatcgtaaa ttcatgcacc tagataccgt ctttacaatg
    20041 gtggattatg ataagttcac gattcaccca gaaatcgaag gagatcttcg cgtttactca
    20101 gtgacctatg aaaatgaaga gcttcgtatt gtagaagaaa ctggtgattt ggctgagctt
    20161 ttagctgcta atctgggagt tgagcgtgtt gagcttattc gctgtggtgg tgataacctt
    20221 gtggcagctg gtcgtgagca atggaacgac ggctcaaaca cgctaacaat cgcaccaggt
    20281 gtcgtggttg tttataaccg taacactatt acgaatgcca ttcttgaatc aaagggcttg
    20341 aagctcatta agattcatgg aagtgaattg gttcgcggtc gtggtggacc tcgttgcatg
    20401 tcaatgccgt ttgaacgtga agacatctag gagaggcaaa tgacaagggt tattgttgga
    20461 aatcagcctt ttcaacgggc agctagctta tatattcgct atcaggtttt tgtcttagaa
    20521 cggcagattg atcggcaaga tgaatttgat tgcttcgacg ataacgatcg cgtgtatgca
    20581 gtcttgtatg atggtgatca gcctgtatcc acagctcgct ttttacccac agctaaagat
    20641 caggctcgtc taacaagagt tgctacgctg cgtcagtatc gtggtagggg ctatggtgcg
    20701 caggtgatag aagcgcttga gcagtatgcc agagagcaag cttacgagcg attggttatt
    20761 catagcgaga ttagcgcaca gtcattttat gaaggtcttg gctatcaagc ctttggcgag
    20821 ccttatgatg aagacggtga gccttgtcaa tcagtagaaa aatatttata aaaaggagaa
    20881 tttaaatgac acaagtattt caaggacgta gcttcttagc agaaaaagac tttacacgtg
    20941 aggaatttga atacctcatt gattttgcag cacacttgaa agaccttaaa aagcgtggta
    21001 ttccacatca ctatttagaa ggtaaaaata ttgccctctt gtttgaaaaa acatcaacgc
    21061 gcacacgtgc tgcctttaca actgcggcga ttgatttagg agctcatcct gaataccttg
    21121 gcgctaacga tattcagctt ggtaaaaagg aatcaacaga ggacacagct aaggtattgg
    21181 gtcgtatgtt tgatgggatt gaattccgtg gctttagcca acgtatggtt gaagaattgg
    21241 cagaattctc aggtgttcca gtgtggaatg gcttgactga tgaatggcac ccaacccaaa
    21301 tgcttgcgga ctaccttact gtcaaggaaa actttggtaa gcttgaaggc ttgaccttgg
    21361 tttactgtgg tgatggacgc aacaacgttg ctaattcact gttagtagca ggtaccttac
    21421 taggtgtgaa tgttcatatc ttctcaccaa aagagctctt cccagcagaa gacatcgtga
    21481 agctggctga gggctatgct aaagcatcag gtgcgcatgt gttagttact gacaatgctg
    21541 atgaggctgt aaagggcgca gatgtgcttt acactgatgt gtgggtgtca atgggtgaag
    21601 aagacaagtt tgaagagcgt gtgaagctct tgaagccata tcaagtgaac atggagcttg
    21661 ttaaaaaagc cgccaacgac aaccttatct tcttacattg cttgccagcc ttccatgaca
    21721 caaatactgt ttacggaaaa gacgttgctg agaaatttgg tgtagaagaa atggaagtaa
    21781 cagatgaggt cttccgcagc aaatacgctc gtcactttga ccaagcagaa aaccgtatgc
    21841 acactattaa agcggttatg gccgcaactc ttggtaatct tttcattcca aaagtgtaag
    21901 ctgtgattgg taccttttaa tttattttag ctcatttcat taatttaaca tttaactact
    21961 aaaaaacgta ctttaactac atgacgagtc gttctggttc tcgtgtcctt gaccggaact
    22021 gggacggctt atttttatga aaaggtaaga ggtaatcact atgacagaag aaaaaaaacg
    22081 aggttttaaa attccttctt cttacactgt tttgtttatc atcattgcta ttatggcagt
    22141 attaacctgg tttattccag ctggtgctta tgagactgct aaggatggcg gtgtgatttc
    22201 agggacctac caaacggtta agtcaaaccc tcagggcttt tttgacattt taatggcacc
    22261 tgttcgaggc atgctaggtg tcaaagggac tgaaggggca attcaggttt ctttctttat
    22321 tttgatggtt ggtggctttt taagggttgt caacaagaca ggtgcgcttg atacagggat
    22381 tgcttctgtt gtgcgtaaaa ataagggtag agaaaagctg cttattgcga ttttgattcc
    22441 tttgtttgca cttggtggca caacctacgg aatgggagaa gaaacaatgg cgttttaccc
    22501 tcttcttatt ccggtaatga ttgcggttgg ctttgatagc attgttgcag tagctattat
    22561 cctgattggt tcacagattg gctgtttggc ctcaaccatc aatccctttg ctactggagt
    22621 ggcagcagat gcagccggtg ttagtatcgc agatggtatg atttggcgga ttatccaatg
    22681 ggttgtcctt gttggtatgt ctatctggtt tgtttacagt tacgctagca agattgaaaa
    22741 agacccaagc aagtccttgg ttgctgacaa agctgaagaa cataaggaat tcttccagct
    22801 gcaaaattcc ggtgaggatt tgactagtcg tcaacgaaag gttttagcca tttttacctt
    22861 gacatttgtc atcatgattc ttagcttgat tccttgggaa gattttgaca ttcaattatt
    22921 tacaaatatc aacacttggc taacaacaac acctgtttta ggtggtatta ttggtaaaac
    22981 aatgggagcc tttggtactt ggtatttccc agaaattacc atgctcttta tcatgatggg
    23041 tgttttagtg gctgttgttt atcgcatgag tgaagatgac ttcttctcag cctttctaag
    23101 tggtgcaggt gagttcctcg gtgttgcgat tatttgtgcg gtagcgcgtg gtatccaagt
    23161 gatcatgaat ggtggtatga ttacagcaac cattcttcat tggggtgaaa caggtcttgc
    23221 aggcttgtca tcacaggtct ttgttgtctt ggcctatatt ttctatttgc caatgtcctt
    23281 cttgattcca tcaacatcag gacttgccgg tgcaacaatg ggaatcatgg ctccgcttgg
    23341 acaattctca aatgttcctg ctcatttggt tatcacagcc ttccaatcag catcaggtat
    23401 cttaaacatg atttcaccaa cctctgctat tgttatggga gcgctcgcac ttggacgtat
    23461 tgatctaggt acttggtgga aatttatcgg caagtttatc gttatggtaa tgcttgttag
    23521 tgttttgttg ttagtagtag cgacattctt ttaagagata ggaggctcct atggaaacct
    23581 atatccaacc aagacaccaa gaggcttgtg tagccgcgat taaaaaaata gtatcttacc
    23641 cttctgtgct aaatgagggg gaaaatgaca caccctttgg ccaagccatt caagatgttc
    23701 ttgaagcaac cttagccctg tgccaagatc ttggttttaa tacctatatt gatcctaaag
    23761 gctattatgg ctatgctgaa ttgggcgatc aaacagaggt gcttgctatc ctttgtcact
    23821 tagatgtggt gcctgctggt gatttgaagc tgtggcataa agatcccttt acttgtattg
    23881 aaaaagatgg ctgcttgtat ggacgtggca ctcaagatga caaggggcca tcgatgatgg
    23941 cactctttgc cactaaagca cttatggacg ctggtgtggt ctttaacaaa cgcattcgct
    24001 ttatctttgg aacagacgaa gaaaccctct ggcgctgtat gaaccgttat aatgaagtag
    24061 aggaggaggc aacctttggt tttgccccag actcaagctt cccattgacc tatgctgaaa
    24121 aggggctttt acaagctaag ctagttggta agggatcgcc taaactcaat cttgaggtgg
    24181 gtcaggccta taatgtcgtt ccagctagag cctcttatca gggagacaag ttggaggcat
    24241 taaaggaaga gcttgacagg cttggctttg aatatgttgt caaagatgac gagctaaccg
    24301 tctatggact tgctcagcat gccaaggacg ctccagatgg gattaatgcc cttatcaggc
    24361 ttgcaaaggc tcttgtagtg cttgagccag agccagtcct tgactttctt gctcatgtgg
    24421 ttgatgaaga cggcagagca gtcaatattt ttggtccagt tcaggacgag ccatcaggag
    24481 ggcttagctt caacgtagct ggtcttacct taacaaaaga gatgacagag attcgtttgg
    24541 acattcggat tccggtctta gcagataaag ataccttagt agaccagtta agccaaaaag
    24601 cgcaggacta cggtctagct tacgaggaat ttgattattt ggcaccctta tatgtgccct
    24661 tggacagcga gctagtaact accctgttag aggtatatcg taaaaaaaca ggggaccaat
    24721 cgccagccca atcatcaggt ggagcaacct ttgctcgtac aatggctaat tgtgtggcct
    24781 ttggagcatt atttcctgat gctgttcaaa cagaacacca agaaaatgaa catatcgtct
    24841 tagcagatgc ctatcgtgca atggatattt acgcggaagc catctaccga ctaacacgat
    24901 aagatgagga gtatcatata tgacaaaaca aaaaattgtt gtcgcacttg gaggaaatgc
    24961 aatcctctca acagacgcgt cagctaaggc acaacaagag gccttggttt cgacatcaaa
    25021 atcactagtg aagttaatca aagaaggcca tgaggtgatt atcacgcatg gcaatggtcc
    25081 gcaggttggt aatctcttat tgcagcaggc agcagctgat tctgagaaaa atccagccat
    25141 gccattagat acctgcgttg ccatgacaga aggcagcatt ggcttttggt tagtcaacgc
    25201 cctagacaat gagctgcaag cccaaggcat cacaaaggaa gtggcagcag ttgtcaccca
    25261 ggtcattgtt gatgaaaatg accctgcctt taaaaatccg actaaaccaa ttggtccttt
    25321 cttaaccgaa gaagacgcta aaaagcaaat ggcagaatca ggtgctagct ttaaggagga
    25381 cgctggtcgt ggctggcgta aggtggtgcc atcaccaaag ccaattggta tcaaagaagc
    25441 taatgtgatt agaagcttag ttgattctgg tgttgtggtg gtcagtgctg gtggtggcgg
    25501 tgtgccagtt gttaaagacc ctgcaagtaa aacgcttacc ggtgtggaag ctgttattga
    25561 taaagacttt gctagccaaa ccctttcaga attggttgac gctgatctct ttattgtctt
    25621 gacaggtgtt gataatgtct atgttaactt taacaagcct gatcaaagaa aattggaaga
    25681 ggtaacggtt tctcaaatga aggaatacat cgctcaggac caatttgctc ccggaagcat
    25741 gctgcctaag gtggaggctg caattgcttt tgtggaaaac aaatcaaatg ccaaagctat
    25801 catcacatcg ttagaaaata ttgacaatgt tctctcagca aatgctggta cacaaattat
    25861 cgcaggctaa ttcagatgac tgcacaatga gcttaggctt ttgtgctttg ataggtttta
    25921 gctgataagc ttgaaaaatt gatttaaaag gttaaattag gttaatttag ccttttcttt
//
LOCUS       DARYYD010000028        24367 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.028, whole genome shotgun sequence.
ACCESSION   DARYYD010000028 DARYYD010000000
VERSION     DARYYD010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24367
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.028"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            8..95
                     /locus_tag="TV188_001128"
     tRNA            8..95
                     /locus_tag="TV188_001128"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:42..44,aa:Ser,seq:gct)
     gene            154..969
                     /locus_tag="TV188_001129"
     CDS             154..969
                     /locus_tag="TV188_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEL1534492.1"
                     /translation="MKKLNLSRLFFWLTSLALLALTLVLLFRVAISPYLSMIIRNPVT
                     KIDAIMSKPFAVIKEGAKELDSLMSAFSENKHLKKELRSYKLDQLQVDKLKSENRELK
                     ELLGLDYGTDNQFAARMISRNPYSWNKSLVIDSGKREIKEKSLVTSELGLIGRVTAVS
                     QSSAHVELLTSGKNIELPIKIVDKDKVIYGNLKAFKSESKTMVASEFNSNDSISLDAK
                     VYTSGLDGETVADIPVGKVTGFKNAADKLKRRIFIKLYADTDNLDYVLVVGKE"
     gene            972..1475
                     /gene="mreD"
                     /locus_tag="TV188_001130"
     CDS             972..1475
                     /gene="mreD"
                     /locus_tag="TV188_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEL1534493.1"
                     /translation="MKKSSELLVLLPFLLFFVDAHVSDLISSMLPEGYSVVSHLFLLF
                     FLILMVAFRSKGVICFFSLLLGLLFDYYYFDHIGILSLALPFGTMIVLGLLRFFSGSI
                     SQLQFFLFFTLYMFLVDVSSFILANSYQLTDMTFPYVMTFQLAPTLIVNLLILFCFRK
                     LILSQFY"
     gene            1571..2749
                     /locus_tag="TV188_001131"
     CDS             1571..2749
                     /locus_tag="TV188_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002996017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1534494.1"
                     /translation="MKKRILSAVLVSGVTLGTATTVGADDLDSKIALQNSVISNLNKE
                     QKAAQDRMKTLQSQVSSLQSEQERLVAKNGELEARSAQFEQEIQVLASQIIARNEKLK
                     GQARSAQKGNTLGYLNALLNSKSISDVITRLVAINRAVSANAQMLEKQKADKLSLEEK
                     QQENQEAINTIASNITAIESNQVALKTQQADLEVAKVDLALQLATAEDEKASLITRKE
                     AAEQAAAQAKAQAEQEAAARAAQAQAQAQSVAAAQAAVTQAVPTPAPAQAQPVVAPAA
                     MVSTPAVSYAYDPSNPYPVGQCTWGVKALAPWVGNYWGNGGQWASSAAAAGFRVGATP
                     MVGSVVVWNDGGYGHVAYVTGVQGGQIQVMEANYAGNQSIGNYRGWFSPGAVSYIYPN
                     "
     gene            2854..3816
                     /locus_tag="TV188_001132"
     CDS             2854..3816
                     /locus_tag="TV188_001132"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEL1534495.1"
                     /translation="MSYSDLKLFALSSNKELAEKVAAAMGIQLGKSTVRQFSDGEIQV
                     NIEESIRGHHVFILQSTSSPVNDNLMEILIMVDALKRASAEKISVVMPYYGYARQDRK
                     ARSREPITSKLVANMLEVAGVDRLLTVDLHAAQIQGFFDIPVDHLMGAPLIADYFDRH
                     GLVGDDVVVVSPDHGGVTRARKLAQFLQTPIAIIDKRRSVDKMNTSEVMNIIGSVEGK
                     KCILIDDMIDTAGTICHAADALAEAGATAVYASCTHPVLSGPALDNIQKSAIEKLIVL
                     DTIYLPEERLIDKIEQISIADLIAEAIIRIHEKRPLSPLFELGK"
     gene            4176..4946
                     /gene="recO"
                     /locus_tag="TV188_001133"
     CDS             4176..4946
                     /gene="recO"
                     /locus_tag="TV188_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEL1534496.1"
                     /translation="MRIQRSLGIVLYNKNYREDDKLVKIFTEAAGKRMFFVKHIGRSK
                     LAPVVQPLTAADFLLKINDSSLSYIEDYNQVEAYRHINEDFFRLSYASYVLALADAAI
                     PDNEPDPQLFAFLKKTLDLMEEGLDYDILTNIFEVQILDRFGVRMNFHDCVFCHRTNL
                     PFDFSHKYSGVLCPQHYHEDERRYGLDPNVIYLLNRFQTLNIDELKTISVNTGMKKKL
                     RLFIDALYEDYVGIRLKSKVFIDDLAKWGDIMKNKQGL"
     gene            5062..6069
                     /gene="plsX"
                     /locus_tag="TV188_001134"
     CDS             5062..6069
                     /gene="plsX"
                     /locus_tag="TV188_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEL1534497.1"
                     /translation="MKKIAIDAMGGDYAPKAIVEGVNQAIESFSDIEIQLYGDQSRIE
                     SYLVKSDRVSIVHTDEKINSDDEPAKAIRRKKNASMVLAARAVKDGRADAVLSAGNTG
                     ALLAAGLFIIGRIKGVDRPGLLSTLPTVDGSGFDMLDLGANAENTAEHLHQYAILGSF
                     YAKHVRGIAKPRIGLLNNGTEATKGDSLRKEVYNFLASDSSLQFIGNVEARDLMSGVA
                     DVVVADGFTGNAVLKSIEGTAMSIMGQLKSAIAVGGVKAKFGALLLKSSLYDLKDTLD
                     YSSAGGAVLFGLKAPLVKSHGSSDAKAIFHTIKQVRTMLETDVVGQLVEEFSKESDVN
                     D"
     gene            6062..6310
                     /locus_tag="TV188_001135"
     CDS             6062..6310
                     /locus_tag="TV188_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514702.1"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEL1534498.1"
                     /translation="MTEEVILEKIIALIKKQRSRIDFDITEKTALKDDLGVDSIELVE
                     FVINIEDEFGIDIPDEDVDGMVSMGDMLNYLVKRLNQS"
     gene            6460..7170
                     /locus_tag="TV188_001136"
     CDS             6460..7170
                     /locus_tag="TV188_001136"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEL1534499.1"
                     /translation="MSNQLIYSGKAKDIYETADDGIVLISYKDQVTMLNGAHKEMIEG
                     KGSLNNQISALIFDRLNRVGVSTHFIKQLSETEQLNKRVAIIPLEVVLRNVAAGSFSK
                     RFGVKEGQALDEPIIELYYKNDALDDPFINDEHVSFLKLATDEQIAYIKQETHRINAY
                     LKEWFASVGLTLVDFKLEFGFDKEGMLILADEFSPDNCRLWDNAGRHMDKDVFRRQLG
                     SLTQAYETVLERLRALDQ"
     gene            7349..11089
                     /locus_tag="TV188_001137"
     CDS             7349..11089
                     /locus_tag="TV188_001137"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEL1534500.1"
                     /translation="MNKRIFVEKKADFQIKAQVLLKELKHQLQLKTLVDLRIVQVYDV
                     FHLDQELLLTAIKHVFSEQVTDQVLSEEALQADLKRYAFFAIEALPGQFDQRAASSQE
                     ALLLLGASTDVTVLTSQLYLVNQDIAAEELEALKQYLLNPVDSRFKDILAGLDDQDFS
                     VADKVIPTLDVFNDYTAENLARYRSEQGLAMEVEDLLFIQDYFKTKGRVPTETELRVL
                     DTYWSDHCRHTTFETELKTLDFSASHFEKQLQATYETYLAMRDELGRSERPQTLMDMA
                     TIFGRYERANGRLEDLEVSDEINAYSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRLSGAGDITSPLSETRKGKLPQQVISRQAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKENVVREKPRTGDVVVLLGGK
                     TGRDGIGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRRGDVTRLIKKSNDF
                     GAGGVCVAIGELAAGLNINLDKIPLKYAGLNGTEIAISESQERMAVVICPKDLEAFMS
                     ACHKENIHAAVVAAVTEKPNLVMTWNGQTIVDIERSFLETNGVRVSVAAKVVDSGAPI
                     PEARQTTAETLEADTIAVLSDLNHASQKGLQTLFDSSVGRSTVIHPLGGRYQMTPVEG
                     SVQKLPVQHGVTKTVSVIAQGYHPYIAEWSPYHGAAYAVIEATARLVATGSHWHKARF
                     SYQEYFQRMDKQAERFGQPVAALLGAIEAQVQLGLPSIGGKDSMSGSFEELTVPPTLV
                     AFGVTTAHVDHILSPEFKAAGENIYYIPGQAISEVIDFELIKSNFMTFEAIQKKHNIS
                     SASAVKYGGVVEALALAAFGNRLGACVTLPELDRSLTAQLGGFIFTSKEEITGVIKLG
                     QTTSDFTLVVNDVKLSGARLLKAFEGSLEQVYPTVFQQAGELKPVPVVTTALAAQFKE
                     KIAQPVVYIPVFPGTNSEYDSAKAFEREGARVNLVPFVTLNEAAIDASVDTMVDHIHQ
                     AHIIFLAGGFSAADEPDGSAKFIVNILLNEKVRMAIDAFIEKGGLIIGICNGFQALVK
                     SGLLPYGRFEAVHEASPTLFYNDANQHVAKMVETRIANTNSPWLAGVRVGDIHAVAVS
                     HGEGKLVVTERELAELCKNGQIFSQYVDLDGNPSMDSRYNPNGSVNAIEGLTSKNGQI
                     IGKMGHSERFEEGLFQNIPGNKDQWLFRSAVHYFRGDHVGID"
     gene            11208..12665
                     /locus_tag="TV188_001138"
     CDS             11208..12665
                     /locus_tag="TV188_001138"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEL1534501.1"
                     /translation="MTYDVKSLNEECGVFGIWGHPHAAQVTYFGLHSLQHRGQEGAGI
                     ISNDNGELHQHRDVGLLSEVFKDSSDLDKLKGHAAIGHVRYATAGTASINNIQPFLYR
                     FTDAQFGLCHNGNLTNAMSLKKALESEGAIFNASSDTEILMHLIRRSHHPEFLGKVKE
                     ALNTVKGGFAYLLMTENQLIAALDPNGFRPLSIGRMKNGAWVVSSETCAFEVVGAEWV
                     RDVMPGEVIIIDDQGITYDCYTTTTQLAICSMEYIYFARPDSTIAGVNVHTARKRMGK
                     RLAQEFQHEADIVVGVPNSSLSAAMGFAEASGLPNEMGLVKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVNLLREAGATEVHVAIGSPELKY
                     PCFYGIDIQTRRELISANHTAAEVCDIIGADSLTYLSLDGLIEAIGLDTKAPNGGLCV
                     AYFDGQYPTPLYDYEEAYLKSLEEKVSFHIDQVTK"
     gene            12722..13744
                     /locus_tag="TV188_001139"
     CDS             12722..13744
                     /locus_tag="TV188_001139"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEL1534502.1"
                     /translation="MSKNAYAQSGVDVEAGYELVERIKKHAERSKRLGVMGGLGGFGG
                     LFDLSKTGVKEPVLVSGTDGVGTKLMLAIQYDKHDTIGQDCVAMCVNDIIAAGAEPLY
                     FLDYLAAGKNEPAKLEQVIAGIAEGCVQAGAALIGGETAEMPGMYGQDDYDLAGFAVG
                     IAEKSQLIDGSRVAEGDHLLGLASSGVHSNGYSLVRRIFAGYTGEELLPELDGKKLKE
                     VLLEPTRIYVKAVLPLIKSGLVAGIAHITGGGFIENLPRMFSKELAAEIEEASLPVLP
                     IFKVLETYGKINHEEMFEIFNMGIGMVLAVKPEHVEQVKACLDEPVYDIGRVVTRTVA
                     SVVMKP"
     gene            13741..14298
                     /gene="purN"
                     /locus_tag="TV188_001140"
     CDS             13741..14298
                     /gene="purN"
                     /locus_tag="TV188_001140"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEL1534503.1"
                     /translation="MTRIAVFASGNGSNFQTIAEQFPVAFVFSDHCDAHVLSRACALG
                     VLSYSFELKDFENKQAYEQTLVALLQRHQIDLIVLAGYMKIVSTTLLDAYEGKIINIH
                     PAYLPEFPGAHGILDAWQAGVSQSGVTVHWVDSGIDTGKIIKQVRVPRLSDDTLESFE
                     ARIHEAEYQLYPEVLDSLGVERLNR"
     gene            14445..15992
                     /gene="purH"
                     /locus_tag="TV188_001141"
     CDS             14445..15992
                     /gene="purH"
                     /locus_tag="TV188_001141"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEL1534504.1"
                     /translation="MTKRALISVSDKRGIVDLARELKHLGWDIISTGGTRLALEEAGV
                     VTVAIDDVTGFPEMMDGRVKTLHPLIHGGLLARRDIEHHLQAAKQNRIELIDLVVVNL
                     YPFKETICRPDVTYDVAVDMVDIGGPSLLRSAAKNHASVTVVVDPTDYPLVLGELAST
                     GSTSYQTRQSLAAKAFRHTAAYDAVIADYFTRQAGETKPEKLTLTYDLKQSMRYGENP
                     QQAADFYQRALPTTYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKERPTVVALKHM
                     NPCGIGQADDIETAWDFAYAADPVSIFGGIVVLNREVDLATAEKLHAIFLELIIAPGY
                     SKEALAVLTHKKKHLRILELPFAAQEASEIEAEYTGVLGGLLVQNQDVVTESPADWIV
                     VTKRQPNEQEMAALAFAWKTIKYVKSNAIVIANDHMTLGVGPGQTNRIASIRIAIAQA
                     TGQLEGAVLASDAFFPFADSIEEIAAAGIKAIIQPGGSIRDSESIAAANQHGITMIFT
                     GVRHFRH"
     gene            complement(16370..17524)
                     /locus_tag="TV188_001142"
     CDS             complement(16370..17524)
                     /locus_tag="TV188_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL1534505.1"
                     /translation="MKKVYQLLASGAILLGGNGAISSATTTISQGQSGIVHAAVLGDN
                     YPSKWKQGFGADPWNMYLRQCTSFVAFRLHSSNGFSLPRGYGNVESWGRIAKHQGYHV
                     DHTPRVGAVAWWDKGFNQSHALYGHVAWVAEVNGDTVIIEEYNYNAGQGPEKYHKRQI
                     HKHQVSGYIHFKDLDHNSTSHTQMLHASQAGSTRLAKSGTYYFSSQSPIKAEATLASP
                     DLAYYHTGQLVHYDQTLVADGYEWLSYIGHSGNHRYIPIHKLPVQPQQHSQASIDKPK
                     PVATTPIKVGDTVAFPGVFRVDQVAQNMIASSELAGGEPTSLNWIDSAPLHETDHKGR
                     IAGNQILQVGDYFVVSGTYKVLKVDQPSKGIYVQMGSRGTWLTIDKAKKV"
     gene            17915..19177
                     /gene="purD"
                     /locus_tag="TV188_001143"
     CDS             17915..19177
                     /gene="purD"
                     /locus_tag="TV188_001143"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEL1534506.1"
                     /translation="MKLLVIGSGGREHAIAKKLLESKGVEQVFVAPGNDGMTLDGIER
                     VDIDISEHSALIAFAKTNHIAWTFVGPDDALAAGIVDEFNQSGLKAFGPSRLAAELEW
                     SKDFAKQIMVKYGIPTAAYGTFSDFAKAKAYIEEKGAPIVVKADGLALGKGVVVAETV
                     EQAVEAARDMLLDNKFGDSGARVVIEEFLAGEEFSLFAFVNGDQFYLMPTAQDHKRAL
                     DGDKGPNTGGMGAYAPVPHLSQSVVDTAVETIVKPVLKGMMTEGRPYLGILYCGLILT
                     EDGPKVIEFNARFGDPETQVILPRLTSDFAQNITDILEGNTANITWSDEGVTLGVVLA
                     SNGYPLAYKKGVLLPAKTTGDIITYYAGVKLAENGKALLSNGGRVYMLVTTAVTVPAA
                     QEKIYTELAQQNTEGLFYRNDIGRKAVK"
     gene            19406..19894
                     /gene="purE"
                     /locus_tag="TV188_001144"
     CDS             19406..19894
                     /gene="purE"
                     /locus_tag="TV188_001144"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEL1534507.1"
                     /translation="MKPIISIIMGSKSDWTTMQKTAEILDQFGLAYEKKVVSAHRTPD
                     LMFTYAEKARERGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGLDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALTALRILSIEDETIAEQLSHFHKEQGRIAEESTHE
                     LN"
     gene            19881..20954
                     /gene="purK"
                     /locus_tag="TV188_001145"
     CDS             19881..20954
                     /gene="purK"
                     /locus_tag="TV188_001145"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEL1534508.1"
                     /translation="MNSTKTIGIIGGGQLGQMMAISAIYMGHKVITLDPAADCPASRV
                     SEVIVAPYSDVEALRQLTERCDILTYEFENVDADALDTVVKEEQLPQGTELLRISQNR
                     IFEKDFLANKASAAVAPYKVVTSSLDLENLDFSKKYVLKTATGGYDGHGQVVIRSEAD
                     LEEANKLANTAECVLEEFVSFDREISVIVSGNGTDVTVFPVQENIHRNNILSKTIVPA
                     RISEAVSAKSQAMAVKIAEQLNLSGTLCVEMFVAGDEILVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGQPLPAVKLHAPAIMLNVLGQHMEQAQRYATENPSAHLHLYGKIE
                     AKHNRKMGHVTVFNSQSDEVEEF"
     gene            20969..21193
                     /locus_tag="TV188_001146"
     CDS             20969..21193
                     /locus_tag="TV188_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEL1534509.1"
                     /translation="MIKIIVHAFIENGETGVVEVVFASENQESISEKMTELQKQYPND
                     YLAIYDLPLDTDLSQLAHYPSIAIGKGEFE"
     gene            21790..23082
                     /gene="purB"
                     /locus_tag="TV188_001147"
     CDS             21790..23082
                     /gene="purB"
                     /locus_tag="TV188_001147"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEL1534510.1"
                     /translation="MLNRYSRPEMAKIWSEENKYRAWLEVEILADEAWAELGEIPKED
                     VAKIRANASFDINRILEIEEETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIVAEKAKEHKMTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNQERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCGKLGIRPQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMVTAYENVALWHERDISHSSAERIITPDTTILINYMLNRFGNIVKNL
                     TVFPENMTRNMNSTFGLIYSQRVMLKLIEKGMTREEAYDLVQPKTAYSWDNQVDFKPI
                     LEADENITAKLRQDELDELFNPAYYTKRVDAIFDRLGL"
     gene            23380..24293
                     /locus_tag="TV188_001148"
                     /pseudo
     CDS             23380..24293
                     /locus_tag="TV188_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677204.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
BASE COUNT         6902 a         4369 c         5826 g         7270 t
ORIGIN      
        1 attatttgga gaattactca agaggctgaa gaggacggtt tgctaaatcg ttaggtcggg
       61 taactggcgc aagggttcga atcccttatt ctccgtattg taaaggtgat tatcatactg
      121 ataatcgttt ttttattttt agaggtgatt ttattgaaaa agcttaacct atctcgtctc
      181 tttttttggt taacatcatt agctttactg gctttgacct tggttcttct ttttagagta
      241 gctatttctc catatttatc aatgattatc cgaaatcccg ttacaaaaat tgatgctata
      301 atgtctaagc cttttgctgt tataaaggag ggtgcaaagg aattagatag cttgatgtct
      361 gctttttctg aaaataagca tttaaaaaag gaacttaggt cctataaatt ggatcagtta
      421 caggttgaca agctaaaatc tgaaaatcga gagctcaagg aactgttagg gttggattat
      481 ggtactgata atcaatttgc tgccagaatg atatcaagaa atccttatag ctggaataaa
      541 tcgctggtca ttgatagcgg caaaagggaa attaaggaga agtctttggt tacttcagag
      601 cttggactta ttggtcgtgt tacagctgtt agccagtcat ctgctcatgt tgaattgtta
      661 acatctggga agaatattga gttgccgatt aaaattgtag ataaggataa ggtgatttat
      721 ggcaatttaa aggcatttaa atcagaaagt aaaacaatgg ttgccagcga atttaattct
      781 aatgactcaa tatcattaga tgctaaggtt tatacaagtg gattagatgg tgagactgtg
      841 gcagatattc ctgttggaaa ggttacgggc tttaaaaatg ctgctgataa gctaaagcgt
      901 cgtattttta taaaattgta tgctgatact gataatcttg actatgttct tgttgttgga
      961 aaagagtgaa tatgaaaaaa tcttcagagc tattagtcct tttgcctttt cttttatttt
     1021 ttgttgatgc acacgtgtca gacctgatca gctcaatgtt acctgagggt tactcggtag
     1081 tatcacacct ctttttactg tttttcctga tccttatggt agcgtttaga tctaagggag
     1141 ttatttgttt cttctctctt cttttaggat tattgtttga ttattattat tttgatcata
     1201 tagggatttt gtctcttgcc ttgccttttg gaacaatgat cgttctaggg ctattaaggt
     1261 tcttttctgg ttccattagt cagctacaat ttttcctttt ctttactctt tatatgtttc
     1321 ttgtagatgt atcaagcttt attttggcaa acagctatca gttaactgat atgacttttc
     1381 cttatgtaat gacgtttcag cttgctccga ctttaatcgt caatctcctt attttgtttt
     1441 gctttagaaa attaatatta agtcaatttt attgattatt acatacaact gtaacagatg
     1501 cgtaacatta aacgcttgat tttttgatag aatataatgt gtcttatcga aaaggagtaa
     1561 tttttttagt atgaaaaaaa gaattctatc agcggttctt gtaagcggtg tgacccttgg
     1621 aacagcaact acagtgggag cggatgattt agattccaaa atagcgttgc aaaattcagt
     1681 tatttctaat ttaaataaag aacaaaaagc tgcgcaggat agaatgaaga ctttgcaaag
     1741 tcaggttagc tcattacaat ctgaacaaga aaggttagtc gctaaaaatg gtgagcttga
     1801 agcgcgatct gctcagtttg agcaggagat tcaagtgctt gccagtcaaa ttattgctcg
     1861 taatgaaaag ttaaaaggac aggctcgtag tgctcaaaag ggaaatacgt taggttacct
     1921 caatgcactt ttgaattcta agtcaatttc tgacgttatt actcgtttgg ttgctattaa
     1981 tagagctgtg tcagccaatg cacagatgtt ggaaaagcaa aaggctgata agctttctct
     2041 tgaagaaaag caacaggaaa atcaagaagc gattaataca attgcttcaa atattacagc
     2101 aattgaatca aaccaagtag ctttaaagac tcaacaagca gatttagagg ttgccaaggt
     2161 agatttggcg cttcaattag caactgctga ggacgagaag gctagcttga ttacccgtaa
     2221 agaggctgca gagcaggcag cagctcaagc caaggctcag gcagagcagg aagcagcagc
     2281 cagagcagca caggctcaag ctcaagcaca gtctgtagcg gcagctcaag cagcagtgac
     2341 tcaagccgta ccaacaccag ctccagcgca ggcacagcct gttgtggcgc cagcagctat
     2401 ggtttcaaca ccagcggtgt cgtatgccta tgatccttct aatccgtacc ctgtcggcca
     2461 atgtacttgg ggagttaagg ctttagctcc ttgggttggc aattattggg gaaatggtgg
     2521 tcaatgggca tcaagtgcag cggcagcagg tttccgtgta ggtgcaacac caatggttgg
     2581 ctctgttgtt gtatggaatg atggtggcta tggtcacgtt gcctacgtaa caggtgttca
     2641 gggtggacag attcaagtta tggaagccaa ctatgctgga aatcaatcta ttggcaatta
     2701 tcgtggttgg tttagcccag gtgctgtatc gtatatttat ccaaattaga aaataagtaa
     2761 aggtaagaat caggattctt acctttttat ttccattgaa aaattgattg aaaagggtta
     2821 aaatggtata ggatcaaaac tttggaggaa aaaatgtctt attctgattt aaagctgttt
     2881 gcattatcgt caaacaagga attagcagaa aaagttgctg ctgcgatggg aattcaactt
     2941 gggaagtcta cggttcgcca gttttcagat ggtgagattc aggtcaatat tgaggaatca
     3001 atacgtggac accatgtttt tattttgcag tcaacaagct cgcctgttaa tgataaccta
     3061 atggaaattt taattatggt tgatgcttta aagcgtgcca gtgctgagaa aatttctgtg
     3121 gtaatgcctt attatggcta tgctcgtcag gatcgtaagg ctcgttcgcg tgagcctatt
     3181 acctctaaat tagtcgctaa tatgctagag gtggcaggtg ttgatcgttt attgactgtt
     3241 gatttacatg ctgcgcagat tcaaggcttc tttgatattc ctgttgatca tctcatggga
     3301 gcacctttaa ttgctgatta ttttgatcgt catggtctag taggtgatga cgttgttgtt
     3361 gttagcccag atcatggtgg tgtgacgcgt gctcgtaagc tggcacaatt cctccaaacg
     3421 ccaattgcta ttattgataa gcgtcgtagt gttgataaaa tgaataccag tgaggtgatg
     3481 aatatcattg gtagtgttga aggtaaaaaa tgtattctga ttgatgatat gattgatact
     3541 gctggtacca tctgtcatgc cgctgatgcg cttgctgaag caggagcaac agcagtttac
     3601 gcatcatgta ctcacccagt gctgtcagga ccagctcttg ataatattca aaaatcagcg
     3661 attgaaaaat tgattgtttt ggatacgatc tatttaccag aagaaagact gattgataag
     3721 attgaacaaa tctctattgc agatttgatt gcggaagcta tcattcgtat ccatgaaaaa
     3781 cgtccattgt cacccctatt tgaattaggg aaatgataag gttagcctga ggtagtaagc
     3841 cttaggcttt tttatgtttt aaaaggctat ttgattacca aagcagtgtt tgatttaacg
     3901 ccatagatag gcttcactgt cttatggtag gtgttgagct attatagcaa aaagtcatgt
     3961 gtaggtgctg tgtttaaaca gctagcctat gattcatata gttatggcta gtgactgttg
     4021 agcttcttat tctcagagtt gttacgagcc ttaagtacag tgttagtcat gcaattttcc
     4081 tggattttgg gtataatata gctgtattta aggtgtttta aaggtctagt aagaaaggca
     4141 ttattactag ctgagaagct tggttatgga gatatatgcg tattcagagg tcacttggta
     4201 ttgtcttgta caataaaaac tatcgtgaag atgataagct cgtaaaaata tttacagaag
     4261 cggcgggcaa gcgtatgttt ttcgtgaaac atattggtcg ttctaaacta gctcctgtgg
     4321 tccagccttt aacggctgct gattttctat tgaaaatcaa tgattcgagc ctttcttata
     4381 tagaggatta taatcaggtg gaggcttatc ggcacatcaa tgaagatttt tttaggctat
     4441 cctatgctag ttatgtcttg gctctggctg atgcggctat tccagataat gagcctgatc
     4501 ctcagttgtt tgcttttttg aaaaagactc ttgatctgat ggaagaaggg ctagattatg
     4561 acattttaac gaatatcttt gaagtccaga ttttggatcg ttttggggtg agaatgaatt
     4621 ttcatgattg tgttttttgt cacagaacca atctgccttt tgatttttct cataagtatt
     4681 caggtgtcct ttgtccgcag cattaccatg aggatgagag gcgatatggc ttggatccca
     4741 atgtgattta tttgcttaat cgttttcaaa cgcttaatat tgatgagcta aagactattt
     4801 ctgtgaatac tggtatgaaa aaaaagcttc gtctttttat tgatgccttg tatgaggatt
     4861 atgtcggtat tcgtctaaaa agtaaggttt ttattgatga tttggctaag tggggagata
     4921 ttatgaaaaa caagcagggc ttgtgagcta ttcaggtgtg gatttgtcct tttatgggaa
     4981 ttgtctgggg aatatgctat aatagttacg ttattctcta ggatattttt cgttaagaaa
     5041 aataggatta aaggagcaaa aatgaagaaa attgcaatag acgctatggg tggtgattat
     5101 gcccctaaag ctattgttga gggtgttaat caggcgatag aatccttttc agatattgaa
     5161 attcagcttt atggcgatca atcaaggatt gagtcttacc tagttaaatc agatcgtgtg
     5221 tccattgttc atacagatga aaaaattaat tctgatgatg agccagcaaa ggctattcgt
     5281 cgtaagaaga atgcttctat ggttttagct gcaagggcag ttaaggatgg tcgggctgat
     5341 gcagttcttt cggcaggtaa tacaggcgcc ttgttagctg ctggtttgtt tattattggt
     5401 cgtatcaagg gagtggatcg tcctggtttg ctgtcaactc tgccaacggt tgatggttca
     5461 ggctttgaca tgttagattt gggtgccaat gctgaaaaca cagcagagca tttacaccaa
     5521 tatgctattt taggctcttt ttatgcaaaa catgtgcgtg gtattgccaa gcctcggatt
     5581 ggcttgctta ataatggtac tgaggcaact aagggtgatt ctcttcgcaa ggaggtctat
     5641 aattttttag cttcagacag cagcctacag tttattggga atgttgaggc aagagatttg
     5701 atgtctggcg tggcagatgt tgtggtagca gatggcttta caggaaatgc tgttttgaag
     5761 tcgattgaag gcactgctat gagtattatg ggacaattga aatcagctat agcagtaggt
     5821 ggtgttaagg caaagtttgg agctctttta ttgaagagta gcctttatga cttaaaggat
     5881 actttagatt attccagtgc gggtggggct gtattgtttg gtcttaaagc acctcttgtg
     5941 aaatcacatg gttctagtga tgccaaggct atttttcata ccattaagca ggttcgtacg
     6001 atgctagaaa cagatgtagt tggccaatta gttgaggagt tttctaagga gagtgatgta
     6061 aatgactgag gaagttattt tagagaaaat catcgcatta atcaagaagc aaagaagtcg
     6121 tatagacttt gacattacag aaaaaacagc actaaaggat gatttaggag tagattcgat
     6181 tgaactggta gagtttgtta ttaatatcga agatgaattt ggtattgata ttcctgatga
     6241 agatgttgat ggcatggtat ctatgggaga tatgctaaat tatttggtca agcgtttaaa
     6301 ccaaagctaa atagttttaa aagagcacca gctctttttt tgtttccgaa aaaacgaaca
     6361 ttataagttt attttatatt aaatgtaaat aaatgttgaa tatttagtat gtttgtggta
     6421 ttgtttagat attaaatgca aagaaaggcg aacaaataag tgtctaatca actcatttat
     6481 tcaggtaagg caaaggatat ctatgaaaca gccgatgacg ggattgtctt aatctcctac
     6541 aaggatcagg tcactatgct aaatggagca cataaggaaa tgattgaagg aaaagggagc
     6601 cttaataatc agatttctgc cttaatcttt gataggctaa atagggttgg cgtatcaact
     6661 cattttatta agcaattatc cgagacagaa cagttaaata aaagggttgc gattattcct
     6721 ttggaggttg ttttacgaaa cgtggccgct ggctcatttt caaagcgctt tggtgttaaa
     6781 gaaggtcagg ctttggacga gccaattatt gagctttatt acaagaatga cgctttagat
     6841 gatcctttca ttaatgatga gcatgtcagc tttttaaagc ttgcgactga tgagcagata
     6901 gcctacatca aacaagagac gcatcgtatt aatgcttatt tgaaggagtg gtttgctagt
     6961 gttgggttga cactggttga ttttaagcta gaatttggct ttgataagga ggggatgctt
     7021 atccttgctg atgagttttc tccggataat tgccgcttgt gggataatgc gggccgtcac
     7081 atggataagg acgtttttcg tcgtcagctt ggcagtttga cgcaagccta tgagactgtt
     7141 ttagaaaggc taagagcatt ggatcaataa agaccagctt atttgttgtc agttaagaaa
     7201 gggagctctt ttttgtccgt catgtaagaa aataaatcag ttcagactat ttgagctgct
     7261 gtctaagaaa ggctgtctgc tattggagaa aagagtcagg ctagttctta ttttgggctg
     7321 gtttctgatt ggacttggta tattaactat gaataaacgt atttttgttg aaaagaaggc
     7381 tgattttcag attaaggcac aggtcctgtt aaaggaattg aaacatcagc tgcagttaaa
     7441 gacactggtt gatttgcgta ttgtgcaggt ttatgatgtg tttcatttgg atcaggagct
     7501 gcttttaaca gctataaagc atgttttctc tgagcaggtc actgatcagg tattgtcaga
     7561 agaagcttta caagcagatt taaaaaggta tgcctttttt gcgattgaag ctctgcctgg
     7621 acagtttgat cagcgtgcgg caagctctca ggaagcctta ttgttgttag gagcctcaac
     7681 tgatgtgact gttttgacct cacagcttta tttggtcaat caagacattg ctgctgaaga
     7741 attagaagcc ttaaagcagt acttgttaaa tccagtggat tctaggttta aggacatatt
     7801 agccggtctt gatgatcagg atttttcagt agcagataaa gtgattccaa cgcttgatgt
     7861 ttttaatgat tatacagcgg aaaatcttgc tcgttacagg tctgagcagg gcctagcaat
     7921 ggaagtggag gatctgctgt ttattcagga ttatttcaag acaaaggggc gagtgccaac
     7981 agagactgaa ctaagggttt tggatacgta ttggtctgat cattgtcgtc acacaacctt
     8041 tgaaacagag ctaaaaacgc ttgatttttc agcttctcat tttgaaaagc agctccaagc
     8101 tacctatgag acctaccttg ctatgcgtga tgagctaggt cgatctgaaa ggcctcaaac
     8161 gcttatggat atggctacca tttttggacg ttatgaaaga gctaatggtc gtttagagga
     8221 tttggaggtt tcagatgaaa tcaatgctta ctcagtggaa attgaggtag atgttgatgg
     8281 tgtcaaggag ccttggctgc tcatgtttaa aaatgaaaca cataatcacc caacggaaat
     8341 tgaacccttt gggggtgctg caacctgtat tggtggagct attcgtgatc ctctgtcagg
     8401 ccgttcctat gtttatcaag ccatgcggct ttctggtgca ggggacatta caagcccgct
     8461 gtcagagact cgtaagggca aattaccaca gcaggttatt tcgaggcaag cagcacatgg
     8521 ttactcgtca tatggcaatc aaattgggct agcgactact tatgttcgtg agtattttca
     8581 cccaggcttt gttgccaaac gtatggagct tggtgcggta gttggtgctg cacccaagga
     8641 aaatgtggtt cgtgaaaagc caaggacagg tgacgtggtg gttttgcttg gtgggaaaac
     8701 aggacgtgat ggtattggtg gtgcgacagg atcatctaag gttcagacag ttgagtctgt
     8761 agaaacagct ggtgcagagg tccaaaaagg aaatgccatt gaggagcgta aaatccaacg
     8821 tctttttcgt cgtggcgatg tgacacgcct catcaagaag tcaaatgatt ttggtgctgg
     8881 tggtgtttgt gtagccattg gcgagcttgc tgctggtctt aacattaact tagataagat
     8941 tcctttaaaa tatgctgggc taaatggaac agaaattgcc atttcagaat cccaagagcg
     9001 tatggctgtc gtgatttgtc caaaggattt agaggccttt atgagcgcct gccataagga
     9061 aaatatccat gctgctgttg tggcagctgt gacagaaaaa ccgaatcttg ttatgacctg
     9121 gaatgggcag acgattgttg atattgaacg ctcattttta gagacaaatg gtgtgcgcgt
     9181 gtctgttgct gctaaggttg ttgacagtgg tgcgccaata ccagaagctc gtcaaactac
     9241 tgctgagaca cttgaagcag ataccattgc tgtcttatca gacctgaacc atgctagtca
     9301 aaagggtttg caaaccctgt ttgatagctc agtgggtcgc tctacagtaa tacatccgct
     9361 tggtgggcgc tatcaaatga cacctgttga aggctctgtt cagaaattac cagttcaaca
     9421 tggagtgaca aagacagtct ctgttatcgc tcaaggctat cacccttata tagccgaatg
     9481 gtcaccttat catggtgctg cttatgctgt aattgaggca actgctcgtc tggtcgcaac
     9541 gggtagccat tggcataagg cacgcttttc atatcaggaa tatttccaaa gaatggataa
     9601 gcaggcagag cgctttggtc aaccggtggc agccttgctt ggagcaattg aagcacaggt
     9661 gcagcttggc ttgccttcta ttggaggtaa ggattcaatg tctggtagct ttgaggaatt
     9721 gacagtgccg ccgaccttgg ttgcctttgg tgtgacgact gctcatgtag atcatatcct
     9781 ttcaccagaa tttaaagctg ctggcgagaa tatttactat attccaggac aggctatttc
     9841 ggaagtgatt gattttgagt tgataaaatc taattttatg acttttgagg ctattcagaa
     9901 aaagcataat attagctcag cttcggctgt taaatatggt ggtgttgttg aagcactggc
     9961 tcttgctgcc tttggtaatc ggttaggggc ttgtgtgaca ttaccagagc ttgacaggag
    10021 cttaacagct cagcttggtg gctttatctt tacatcaaaa gaggaaatca caggtgttat
    10081 caagcttggt caaactacca gtgactttac attggttgtc aatgatgtca agctatctgg
    10141 agctcgtctc ttaaaggctt ttgaagggag cctggagcag gtttacccga cggtatttca
    10201 gcaggcaggt gaattgaagc ctgttcctgt agtgacaaca gcacttgctg ctcagtttaa
    10261 ggaaaaaata gctcagccag ttgtctatat tccagttttt ccaggaacta actcagaata
    10321 tgattcggct aaggcctttg aaagagaggg tgcaagggtg aacttggtgc cttttgttac
    10381 cttgaatgag gcagctattg acgcttcagt tgacacgatg gttgaccata ttcatcaagc
    10441 tcatattatc ttccttgcag gtggtttttc agcggcagat gagccagatg gttcagctaa
    10501 atttattgtt aatatcctgc tgaatgagaa ggttcgaatg gcgattgatg cctttattga
    10561 aaagggtggt ctgattatcg gtatttgtaa tggctttcaa gctctggtca aatcagggct
    10621 gctgccatat ggacgttttg aggcggtaca tgaggctagt ccaactctgt tttataatga
    10681 tgccaatcag catgtggcta aaatggtaga aacgcgtatt gccaatacca attctccttg
    10741 gctggcaggt gtcagggtgg gggatattca tgctgttgca gtgtcacatg gagagggcaa
    10801 gcttgtggta acagaaagag aattagcaga gctttgtaaa aatggtcaga tttttagcca
    10861 gtatgttgac cttgatggta atccaagcat ggatagcagg tataatccaa atggctctgt
    10921 caacgctatt gaaggtctta ccagcaaaaa tggtcagatt atcggtaaga tgggacattc
    10981 agagcgcttt gaagagggac ttttccaaaa tattccgggt aataaggatc aatggttatt
    11041 ccgaagtgcg gtgcattatt ttagaggaga ccatgtgggt attgactgaa ctgggatata
    11101 gccttgtaat agctaagata gctgctatta ttgctcagcc tagctgttag ttctagctta
    11161 gttaatgaca caatcataat taaaagggca ttagcccaga ggtaaagatg acatatgacg
    11221 taaaatctct taatgaggaa tgtggtgttt ttgggatttg gggacaccca catgccgctc
    11281 aagtgactta ttttgggctt catagcctac agcaccgcgg ccaagaggga gcaggtatta
    11341 tttcaaatga taatggggag cttcatcagc atcgtgatgt aggtctcttg tcagaggtgt
    11401 ttaaggattc atctgatctg gacaagctaa agggacatgc tgccattggt catgtgcggt
    11461 atgcgactgc tgggacggct tccattaata atattcagcc ctttttatat cgttttacag
    11521 acgctcaatt tggcttgtgc cacaatggta atttgaccaa tgctatgtca ttgaaaaaag
    11581 cgttagagag tgagggagct atttttaatg cctcttctga tacagaaatt ctaatgcatt
    11641 tgattcgtcg tagtcatcac ccagaatttt taggaaaggt aaaagaggca ctcaacactg
    11701 ttaaaggggg ctttgcttac ctgctgatga cagagaacca gctgatagca gcgcttgatc
    11761 caaacggctt taggccgttg tctataggcc gtatgaaaaa tggggcttgg gtcgtctcaa
    11821 gtgagacctg tgcctttgaa gtggttggtg ctgagtgggt tcgcgatgtg atgccaggtg
    11881 aggtcattat cattgatgat caggggatca cttatgactg ctatacgact actacgcagc
    11941 tggctatctg ctctatggaa tatatttact ttgcgcgtcc tgattcaacc attgctggag
    12001 tcaatgttca caccgctcgc aagcgaatgg gaaagagact ggctcaggaa tttcagcatg
    12061 aggctgatat tgtggttggt gtgccaaatt cctcattatc agcagcgatg ggctttgcag
    12121 aagcatcagg cctgccaaat gaaatgggat tggtcaagaa tcaatatacc caacgaacct
    12181 ttatccaacc aactcaggag cttcgtgagc agggagttcg aatgaaactt tcagctgttt
    12241 caggtgttgt caagggcaaa agggttgtga tggtagatga ttctattgtc agagggacaa
    12301 cctcacgacg cattgttaat ttgctgcgtg aagcaggagc tacagaggtt catgtagcaa
    12361 ttggtagccc tgagctcaaa tacccttgct tttatgggat tgatattcag acaagacggg
    12421 agctgatttc agctaatcat actgctgctg aggtctgtga tattatcggt gctgatagcc
    12481 tgacttattt gtcacttgat gggcttatcg aggctattgg acttgataca aaagcaccaa
    12541 atggtgggct ttgtgtggct tattttgacg gtcagtatcc aacgccgctt tatgattatg
    12601 aggaggctta tctcaagagc ttagaagaaa aggtaagctt tcacattgat caggtgacga
    12661 agtagcgctt tatggctaac atagaataaa tgatctaggc agctaaaata aggaggagaa
    12721 aatgtctaaa aatgcttatg ctcaatcagg tgtcgatgtt gaagcaggct atgagcttgt
    12781 tgagcgaata aaaaagcatg ccgagcgtag caaacgattg ggtgttatgg gtggtctagg
    12841 aggctttggt ggtctgtttg acctgtcaaa gactggtgtt aaggagcctg ttttggtttc
    12901 agggacagat ggcgtcggaa caaagctaat gcttgcaatc cagtacgata agcatgacac
    12961 gattgggcag gattgtgtgg caatgtgtgt caatgatatt attgcagcag gtgccgaacc
    13021 cctgtatttt cttgattacc ttgcagcagg aaaaaatgag cctgccaaat tagagcaggt
    13081 gattgcaggt attgctgagg gctgtgttca agcaggtgct gctcttatcg gtggagaaac
    13141 tgctgagatg cctggtatgt atggtcaaga tgactatgat cttgccggtt ttgcggttgg
    13201 tattgctgag aaatctcagc tgattgatgg ttcaagagta gctgagggag atcatctcct
    13261 aggtttggca tcaagtggag ttcattcaaa tggttattcc ttggttcgtc gtatttttgc
    13321 cggttatact ggtgaggagc tgcttccaga gcttgatgga aaaaagctta aggaggtact
    13381 tcttgagcca actcgtattt atgtcaaggc tgtgttacca ctcattaaaa gcggcttagt
    13441 ggcaggaatc gctcatatta cgggtggcgg ctttattgaa aacctacctc gtatgttttc
    13501 caaagaacta gccgctgaaa ttgaagaagc cagcttacct gtgctgccca tttttaaagt
    13561 ccttgagaca tatggtaaga tcaatcatga agaaatgttt gagattttta atatgggtat
    13621 tggcatggtg cttgctgtca agcctgagca cgttgagcag gtgaaggcct gtcttgatga
    13681 gcctgtgtat gacattggtc gcgttgtgac cagaacagtt gctagtgtgg tgatgaagcc
    13741 atgacaagaa ttgccgtttt tgcttctggt aatggctcca attttcaaac gattgcagaa
    13801 cagtttccgg ttgcctttgt tttttctgat cattgcgatg ctcatgtttt aagtagagcc
    13861 tgtgctttgg gtgttctgtc ctacagcttt gaactaaagg actttgagaa taagcaagcc
    13921 tatgagcaga ctcttgtggc attgctgcag cggcatcaga ttgatctcat cgtccttgcc
    13981 ggctatatga aaattgtgag tacaacctta cttgatgctt acgaaggaaa aatcatcaac
    14041 attcacccag cttatttgcc agaatttcca ggagcacatg gtattttaga tgcttggcaa
    14101 gcaggtgtta gtcagtcagg agtgactgtt cattgggttg atagtggtat tgatacagga
    14161 aaaatcatca aacaggtacg agtaccacgt ttgagtgatg atactcttga aagctttgaa
    14221 gccagaattc atgaagcaga ataccaattg tatccagagg tactggatag tcttggagta
    14281 gagcggctta accgctgatt gtgtaagatt aataactatt ttccctattg tggcatttcg
    14341 tttatcatag cagctgcgct aatggtggct aacaaaggct agaagacttg tttgatgatg
    14401 gcactgctat tgaggaaaat agacttttct aaggagaact taaaatgact aaacgcgcct
    14461 taattagcgt atcagataaa agagggattg tggaccttgc tagggagctt aagcatcttg
    14521 gctgggatat tatatcaaca ggaggaacaa ggcttgctct tgaagaggct ggtgtagtta
    14581 ctgttgctat tgacgatgtg acaggctttc ctgaaatgat ggacggacgg gtaaaaacgc
    14641 tgcaccctct cattcatggt ggcttacttg ctcgtcgtga cattgagcac cacttacagg
    14701 cagcaaagca aaacaggatt gaattaatag accttgttgt tgttaacctt tatcccttca
    14761 aagaaaccat ttgccgtcca gatgtcactt atgatgtcgc tgttgatatg gttgatattg
    14821 gtggtccttc actgctgcgt tcagcggcta aaaatcatgc tagtgttacg gtagtggttg
    14881 atccgacaga ttatccgctc gttttaggag agttggctag cactggcagt acaagttacc
    14941 aaacccgtca aagcttagca gctaaagctt ttcgccatac tgcagcctat gatgcagtga
    15001 ttgcagatta ttttacaaga caagcaggtg agacaaagcc tgaaaagctc acgcttacct
    15061 atgatttgaa gcaaagcatg cgttacggtg aaaatcctca acaggctgca gatttttacc
    15121 aaagagcgct cccaacaacc tattcaattg cttcagccaa gcagctaaat ggaaaagagc
    15181 tatcattcaa caatattcgt gatgcagatg ctgcgattcg tattattcgt gattttaagg
    15241 agcgtccaac cgttgtagca ctcaagcata tgaatccatg tggtattggt caggcagatg
    15301 atattgagac agcttgggat tttgcttatg cagctgatcc ggtgtctatc tttggtggta
    15361 ttgttgtcct aaatcgtgag gtggatctag cgacagcgga gaagcttcat gctatttttc
    15421 ttgaattgat cattgcacca ggctattcca aagaagcgct agctgttctc acccataaaa
    15481 agaagcactt gcgaattctt gaattgccat ttgctgctca ggaggctagt gaaatagaag
    15541 cagaatatac aggagttctt ggtggtctac tagtgcaaaa tcaagatgtt gtcacagagt
    15601 ctccagcgga ttggatagtg gtgacaaagc gtcagccaaa tgaacaggaa atggctgctc
    15661 tagcatttgc ttggaaaacc atcaaatatg tcaagtctaa tgcgattgtc attgctaatg
    15721 atcatatgac tttgggcgtt ggtccagggc aaacaaaccg aatagcctct attcgtattg
    15781 ctattgcgca agcaacgggg cagcttgagg gagcagttct tgctagcgat gccttcttcc
    15841 catttgcaga cagcattgaa gaaattgctg ccgctggtat caaggctatt atccagcctg
    15901 gaggctctat tcgtgattca gaatctattg cagctgccaa tcagcatggt ataaccatga
    15961 ttttcacagg tgtgaggcat tttagacatt aataaagtaa aaagagactg gagccaaaag
    16021 agttgcactt tagaaattct tggttaatat actttattac ctagttggat tcattaaaaa
    16081 gcgaacaagt ctagttttca taatctcaga aaactagact tgtttgcttg ttttatttgg
    16141 tggtcatact attgtttcag cctcttttta ctatgactaa tacaagaatt tatgaaggaa
    16201 caaggcttta ttttttgttg tggtaacagt gaccagatcc gttatcaatc agtatttgag
    16261 tattttgagc tctagatgca tcacttagat aggatattgc aaaggataca gctgctgcat
    16321 gtattaggaa agcattatca taaaaggctt tttcgttagc ctaaaggttt tagaccttct
    16381 ttgccttatc tattgttaac catgttccac gtgaacccat ttgcacgtaa atccccttgc
    16441 taggctgatc aacctttaga accttatagg ttcctgaaac gacaaaataa tcacccacct
    16501 gcaaaatctg atttccagca atacgtcctt tatggtccgt ttcgtggagt ggagctgagt
    16561 ctatccagtt taaggaggtt ggctctccac cggctaattc actgcttgca atcatgttct
    16621 gagcgacctg atcgacccga aaaacaccag gaaaggctac agtatctcca accttgatag
    16681 gagtggtcgc cacaggcttt ggtttatcta tagaggcttg actatgttgc tgaggctgaa
    16741 ccggcaattt gtgaattgga atgtagcgat gatttcctga atgaccgata tagctgagcc
    16801 attcatagcc atcagcgaca agggtttgat catagtgcac taactgtcca gtatgatagt
    16861 aagctaaatc aggacttgct aatgtagctt cagcctttat aggactttgg cttgaaaaat
    16921 aataggtacc acttttagct agacgagttg atcctgcttg agaagcatgt aacatttgtg
    16981 tgtggctggt agagttgtga tccagatcct tgaagtgaat gtaaccactt acctgatgct
    17041 tatgaatctg tcgtttatga tacttttcag gtccctgtcc ggcattatag ttgtattcct
    17101 caataataac agtgtcacca ttgacctctg ctacccaggc gacgtgtcca tatagggcat
    17161 gtgactggtt aaagccctta tcccaccaag caacagcacc aactctaggt gtatgatcaa
    17221 catgatagcc ttggtgttta gctatacgtc cccagctttc aacattacca tagcctctag
    17281 gcaggctgaa tccatttgag gaatgcagtc ggaatgctac aaaagaagtg cattgacgta
    17341 agtacatgtt ccaaggatca gctccgaagc cctgtttcca cttacttgga tagttatccc
    17401 ctaaaacagc agcgtgtacg atacctgact gaccttgtga aatcgttgtt gtggcagagg
    17461 atattgcacc attaccacct aaaaggattg ctcctgaagc taacaattga tagacttttt
    17521 tcattaatta cctcctgtaa cttactattc gcaagaaaga ggacaaaaat gtccttgatt
    17581 taaaaaaatg taaggaaaaa tattttagcc tcaaaatact gttggtgctc cctagcttcc
    17641 aagagccaat aggcaagccc atctccagct tgcctgctcc ctgtagctaa aagcaattta
    17701 tagtaacact agcacctcat ctgaagaggc aggctgtggt aattaatgcc aataatctgt
    17761 aaaaagagac agcaggtatg gttatatgag ctatgatggt tatattctat aaagcttatt
    17821 ttttagcttc gggctttctt tggtgattag ttatttatat aaacgaacaa ttatgctaaa
    17881 atatgtttat aaaattcgtg ttatgaggtg tgtgatgaag cttttagtta tcggttcagg
    17941 tggtcgtgaa catgcgattg ctaagaaatt gttagagtca aaaggcgttg aacaggtttt
    18001 tgtggcacct ggcaatgatg gcatgaccct tgatggcata gaacgggtag atattgatat
    18061 ttccgaacat tctgctttga ttgcttttgc aaagaccaat catatagcct ggacctttgt
    18121 gggaccagat gacgcattag cggctggtat cgttgatgag tttaaccagt ctggcttgaa
    18181 agcctttggg ccctctcgtt tagcagcgga gctggagtgg tcaaaggact ttgctaagca
    18241 aatcatggtc aaatacggta ttccaacagc agcctatggc acattttctg attttgcaaa
    18301 agccaaggcc tacatcgagg aaaagggcgc gccaattgtg gttaaagcag atggtttggc
    18361 gctaggaaag ggtgttgtcg tagcagagac tgtagagcag gcagttgagg cggcgcgtga
    18421 catgctcttg gataataaat ttggtgattc aggtgcgcgc gtggtgattg aggaattttt
    18481 agctggtgaa gagttctctc tctttgcctt tgtgaatggc gatcagtttt acctcatgcc
    18541 gacagcgcag gaccacaagc gggctcttga tggtgacaag gggccaaata caggtggtat
    18601 gggggcttat gcaccagtgc ctcatctttc tcaaagtgtg gtggatacag cagttgagac
    18661 cattgtcaag cctgttctaa aagggatgat gacagagggg cgtccctatc ttggaatcct
    18721 ttactgtggc ttgattttga cagaagatgg accaaaagtg attgaattca atgctcgctt
    18781 tggtgatcct gagactcagg ttatccttcc tcgcctgacc tctgattttg cacagaacat
    18841 taccgatata ttagagggca acacagctaa tatcacatgg tcagacgagg gagtgacgct
    18901 cggcgttgtc cttgcttcaa acggttatcc gcttgcttac aagaaaggtg tgcttctgcc
    18961 agcaaagacc actggcgaca tcattaccta ctacgcaggg gttaagcttg cggaaaatgg
    19021 caaagcactg ctgtcaaatg gtggacgtgt ctatatgctg gtcaccacag cagttaccgt
    19081 cccagctgcg caagaaaaaa tctataccga acttgctcag caaaataccg aaggattatt
    19141 ctaccgaaac gatattggaa gaaaagcagt aaaataaatt agcgctagct caagctaccg
    19201 aaggtcgcta tgatgacaat gacttattat cggtgagcaa aagcgagcct aacacgatac
    19261 ttttcgccgt agcgcaaaga gtgacaaggt cactcggggg aacttgaaag accttgggct
    19321 ttcaagttag tcatgagaca cctatggtgg ctgttgacgc ccccccccac ttaagaaaag
    19381 tatcaaaaac ctttaaggag aaagtatgaa accaattatc tctatcatca tgggctccaa
    19441 atctgactgg accaccatgc aaaaaaccgc cgaaatcctc gaccagtttg gccttgccta
    19501 cgaaaaaaaa gtggtctctg cccaccgcac gccggatctc atgttcacat acgctgagaa
    19561 agcacgcgaa cgtggcatta aaatcatcat cgctggtgct ggcggagcag cccatctccc
    19621 tggaatggtc gctgcaaaga cgacacttcc tgttatcggc gtacctgtca aatcgcgtgc
    19681 tcttagtggt cttgattcgc tgtattcaat tgtgcagatg ccaggtggtg tgcctgtggc
    19741 aactatggcc attggagagg caggagcaac caatgcagca ctgactgctc ttcggatcct
    19801 ttcaattgag gatgaaacaa tcgcagagca gctcagccat ttccacaaag agcaaggacg
    19861 gatcgcagag gagtcaaccc atgaactcaa ctaaaacaat tggaattatc ggaggtggtc
    19921 agctgggaca gatgatggcg atttctgcca tttatatggg gcataaggtc attacactgg
    19981 atccagcagc ggattgccca gcctcgcgcg tgagtgaggt tatcgtggcg ccttatagtg
    20041 atgtggaggc gctgcgtcaa ttgaccgagc gctgtgatat tttgacctat gaatttgaaa
    20101 atgtggacgc tgacgccctt gatacagtgg taaaggagga gcagctgcct caaggaacag
    20161 agttacttcg gatctcgcag aatcgtattt ttgaaaaaga ttttttagcc aataaagcaa
    20221 gcgcggcagt ggcaccctac aaggttgtaa cctctagcct cgacttggaa aaccttgact
    20281 tttcgaaaaa atacgtcctc aagacagcga caggtggcta tgatggacac ggtcaagtcg
    20341 ttattcgctc cgaagcagac cttgaagagg ctaataagtt ggctaacact gccgagtgcg
    20401 tcttggaaga atttgtcagc tttgaccgag agatttccgt tattgtatct ggcaatggca
    20461 cagatgtcac tgtctttcct gttcaggaaa atatccatcg gaacaatatc ctgtcaaaaa
    20521 ccattgtccc agctcgcatt tcagaagcag ttagcgctaa atcgcaggct atggcggtga
    20581 aaatagcaga gcagcttaac ctatctggca ccctctgtgt agaaatgttt gtggcaggcg
    20641 acgagatttt ggtcaatgaa atcgccccac gtccccacaa ctcaggacat tactccatcg
    20701 aagcctgtga tttctcccag tttgacaccc acattttagg tgtattaggc cagccattac
    20761 cagctgtcaa actccatgcc ccagccatta tgctcaacgt cctcggccag cacatggaac
    20821 aagcccaacg ctacgccaca gaaaacccta gcgcccacct ccacctctat ggtaaaatag
    20881 aagccaagca caaccgcaaa atgggacacg tgacggtgtt taacagtcaa tcagatgagg
    20941 ttgaagaatt ttaggaggaa ttaatcctat gataaaaatc attgttcacg cttttattga
    21001 aaatggtgaa acaggtgttg ttgaagttgt ctttgcttcg gaaaaccaag aatccatttc
    21061 tgaaaaaatg acggagctac aaaagcaata tccaaacgat taccttgcta tctatgattt
    21121 accactagat acagacctat cgcaattggc ccactatccg tcaatagcga taggcaaagg
    21181 ggagtttgag tagttaagga agattagtat ttcggattga gtgttattgg gacaatttat
    21241 ggctatgcct ttcaaaagat tggtcatgat gttgagcatg ttgtgagaat tgagaatcgt
    21301 aatcagattt cagaagttgg taaatgactt aatggataat tctagatact gatctcgagc
    21361 aatcataaga gaaatgttga aattgtagct tctggaggtg tagaactcaa aaattatcgt
    21421 ggtgagatat ttccatataa aacttctaag cgtatttcgt ctagattgat aacatataga
    21481 taggtttgta cataatgaac ttactagatg catcatgaca aagcagatct tttatataca
    21541 tgcaaagagg tttacaatat tggtatagtc aactattgat gccctaactt ttaatcacaa
    21601 tatagaaatt attgcgaata gactttaaaa gcattactat taactatgta gaaaggaaat
    21661 gagcgctaga attttcaaac tgaacctgag cggaaagctc ggaatttaga taaatttcct
    21721 cggacgtaaa tgtccgtctt tagctttcta aaattcagtt gctttctggc tgttcttggt
    21781 atcttaatta tgctaaaccg ttattcacgc cctgagatgg cgaagatttg gagtgaagag
    21841 aacaagtacc gtgcttggtt ggaggtggaa atcctcgctg atgaggcatg ggctgagttg
    21901 ggtgagattc ccaaggaaga tgtggcgaag attcgcgcca atgcgagttt tgacatcaat
    21961 cgtattttgg agattgaaga agagacccgt cacgatgtgg tggcctttac tcgtgcggtg
    22021 tctgaaacgc tcggtgagga gcgcaagtgg gtccactatg gcttgacatc gactgacgtg
    22081 gtggatacgg cctatggcta tctctacaag caggctaatg acattatccg tcgtgacctt
    22141 gaaaacttta ccaacattgt ggctgagaag gctaaggagc acaaaatgac tatcatgatg
    22201 gggcgtactc atggtgtgca cgcggagcca acgaccttcg gtctcaaatt ggcgacctgg
    22261 tacagtgaaa tgaagcgtaa tcaagagcgt tttgagcatg cggctgctgg tgttgaggcc
    22321 ggtaaaatct caggtgctgt tggaaacttt gccaatatcc caccatttgt tgaggagtat
    22381 gtctgtggca agctaggcat tcgcccgcag gaaatctcaa ctcaggtctt gccacgagac
    22441 cttcatgccg agtacttcgc agtgcttgct agtatcgcga catcaattga acgcatggca
    22501 actgaaattc gaggcctgca aaaatctgag caacgtgagg tagaagagtt ctttgccaaa
    22561 ggacaaaagg gaagctctgc catgcctcat aagcgtaacc cgatcggctc tgaaaacatg
    22621 acggggcttg cgcgtgtcat tcgtgggcac atggtgacag cctatgagaa cgtggcgctt
    22681 tggcatgagc gtgatatttc gcactcgtca gcagagcgga ttatcacacc agacacgact
    22741 atcctcatca actacatgct caaccgtttt ggcaatatcg tcaaaaattt gacagtcttt
    22801 ccagaaaaca tgactcgtaa catgaactct acctttggct tgatttacag ccaacgtgtg
    22861 atgcttaagc tgatcgaaaa aggcatgacg cgtgaggagg cgtatgactt ggtacagcca
    22921 aagacagcct attcatggga caaccaagtg gacttcaagc cgatccttga ggcagacgaa
    22981 aatatcactg caaaattaag gcaagatgag cttgatgagc tcttcaatcc agcttattat
    23041 accaagcgtg tcgatgctat tttcgaccga ttaggattat aggaagaaaa cagcgcgtct
    23101 ttttagactg tagctaagcc cagatttgtt taaaaagtct tgaaaatgaa ttcctcggag
    23161 ctaattctca aaatgaagaa tagtatttca agagaggctg tcactagcta tatcgcttaa
    23221 gaaaatgctc taaaatagac attttttcaa tctgagaagg caataggcct tctttttttc
    23281 taaaaataca gaaatgttat tatagaatgg agtcaaaaaa ttaataatta attaaattat
    23341 gtgatataat gaaagaaata gtgtcttgaa gagggaaaca tgttagacaa ttttggtgaa
    23401 aaggtgagag accttcggta tcagaaaaaa attaccagag aggatttatg tggagatgag
    23461 tcagaattat ccattcgtca attggcacga atagaactgg gccaatcgat tcccagccta
    23521 tcaaaggtgg tttttattgc taaggctttg gacgttagtg tcggcttttt gacagacgga
    23581 gaggatttgg agctaccgaa gcgctatagg agcttaaata tttgatttta agaacaccga
    23641 cctatatgga cgatgacaaa ttaaagctgc gagaagagca atttgacgaa atttttgaag
    23701 attattatga ccagttgcca gaggaagaaa agcttgtggt ggattgcttg cagtccataa
    23761 tggatacgtt attaaccgag aatatcaatt ttggagttgg gttattacag gaatactttg
    23821 aacaaacaaa aagtaagact caatttagag agaatgatct cattcttatt gagctgtatt
    23881 tagcgtacct cgacattgca ggaatgaatg gagagtattc agataaagga ttctatgatt
    23941 ctttgttaga cattttgtta aatcagtttg aacattttga attagaggaa ttatttattg
    24001 tcaataaaat agctatagga atttcctcgt tgagcatcaa aaacaataag ccggagattc
    24061 ttgagaaggt tattgtactt agtcaaaaaa ttatcctcaa gactcaggat tttaatagaa
    24121 tgcctatctt aaatttgata gagtggaaat atgctctaat gaagaaaaaa gacatagaaa
    24181 tggccaaaaa atgctatgct aaggcatgcc tgtttgctca attaacagga gatcagtatt
    24241 tggaaaagaa attgagagaa gaatggggta aagatataaa acgatatcaa taggacaaaa
    24301 atgtcatttt tatcaaaaat ggaataatat ataatcttta tataacaaat aattgattaa
    24361 aggagtt
//
LOCUS       DARYYD010000029        24230 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.029, whole genome shotgun sequence.
ACCESSION   DARYYD010000029 DARYYD010000000
VERSION     DARYYD010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24230
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.029"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            312..2456
                     /gene="pnp"
                     /locus_tag="TV188_001149"
     CDS             312..2456
                     /gene="pnp"
                     /locus_tag="TV188_001149"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEL1534511.1"
                     /translation="MSKQTFTTTFAGKPLVVEVGQVAKRANGATVVRYGESTVLTAAV
                     MSKKMSTGDFFPLQVNYEEKMYAAGKFPGGWMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDEDASAPMAAMLGSSLALSISDIPFNGPIAGVQVAYVEGEFI
                     INPDKAQQEASLLELTVAGTKDAINMVESGAKELPEAIMLEALLVGHKAIQELIAFQE
                     EIVAAVGKEKAEVELLQVAADLQAEIIETYNADLQQAIQVEEKKAREAATEAVKERVI
                     AAYEERYAADEEHDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRRVDEIRPLAAEI
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGDTQIIDGLEPEYKKRFLHHYNFPQYSVGE
                     TGRYGAAGRREIGHGALGERALAQVLPSLEAFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGTNYTVLTDIQGLEDHFGDMDFKVAGTRQGITAL
                     QMDIKIEGITPQILEEALAQAKKARFEILDLIEATIAEPRPELAPTAPKIDTIKIDVD
                     KIKVVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIASLVREAKV
                     GEVYHAKVVRIEKFGAFVNLFDKTDALVHISEIAWSRTTNVSDVLEIGEEVDVKVIKV
                     DDKGRIDASMKALVPRPPKPEKSEAKKEGKHD"
     gene            2449..3201
                     /locus_tag="TV188_001150"
     CDS             2449..3201
                     /locus_tag="TV188_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SseB family protein"
                     /protein_id="HEL1534512.1"
                     /translation="MTNTNELDIRLRAFINAPDNFLDSVALVNAFHQYPVWAAKKPYA
                     IEIEGVRIFPVFTDKDDMATFKEEQKSAQAQYWVERSALTVLEEAVHAGAAGLGFNLK
                     KKGDFGNSTVFKSADMIQFMNNYTTILNTLMSDDNSAADTLDRLYLVPAFVYPKEEEH
                     YYDRLFPTMSTPEGKRYVPAFSNLQSFAKWYNQEEFGGLFRKSGGVILTWKIADIYQP
                     RNGNNDIDETFGVAIDPFDDQQILVDWSDIDT"
     gene            3213..3749
                     /gene="cysE"
                     /locus_tag="TV188_001151"
     CDS             3213..3749
                     /gene="cysE"
                     /locus_tag="TV188_001151"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEL1534513.1"
                     /translation="MGWWKDNIDIVKQLDPAARSTLEVILTYPGLKALAAHRLSHFLW
                     QHGFKLLARMHSQFWRFWTQIEIHPGARIASGVFIDHGAGLVIGETAIVEKGAMLYHG
                     VTLGGTGKDRGKRHPTVREGALISAHAQIIGPVEIGKSAKVGAAAVVLTDVPAGVTVV
                     GIPAQIVRVHEKKPSRQD"
     gene            3867..5210
                     /locus_tag="TV188_001152"
     CDS             3867..5210
                     /locus_tag="TV188_001152"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEL1534514.1"
                     /translation="MIKIYDTMTRSLREFVPITDKVVNMYVCGPTVYNYIHIGNARSA
                     VAFDTIRRYFEYAGYTVNYISNFTDVDDKIIKAAKESGVSPKELADRFIAAFMEDTKA
                     LGVKPATKNPRVMDYMDEIIAFIAALIKKGYAYESAGDIYFRVAKASNYARLANKTIA
                     DLEAGASGRTDTETALKEDPLDFALWKSAKLGEISWASPWSAGRPGWHIECSVMATEL
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTSKTFANYWMHNGFVNVDNEKMSKSLGNF
                     VTVHDLLKTVDGQTLRFFLATQHYRKPINFTEKAIHDAGVNLKYLKNTLQQPTVATAD
                     ASQLAAFITAFKAAMNDDFNTANGITVLFDMAKWINSGAYSEAVKSAFEEMLAVFGIV
                     FEAESLDTEIEQLIAERQEARANRDFARADAIRDQLAAQGIKLLDTKEGVRWIRG"
     gene            5203..5610
                     /locus_tag="TV188_001153"
     CDS             5203..5610
                     /locus_tag="TV188_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEL1534515.1"
                     /translation="MANSVDVNLINGIALAFVGDAVYSYYIRRHLIFQGQTKPNKLHY
                     LATKYVSAKAQASLIQAMLEAQLLTEKEKDIYKRGRNTNSHTKAKNADVVTYRMSTGF
                     EAIMGYLDMTGQTERLELLIQWCIKQVENSPQS"
     gene            5827..6615
                     /locus_tag="TV188_001154"
     CDS             5827..6615
                     /locus_tag="TV188_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534516.1"
                     /translation="MKPMRNVALVISAMLLLSSQAFVSAVAAQDNQPTIAVQAQAAAE
                     ANVSARMRSDQPVIEANIATSQPVSQSTEATILLKDAKGNAINSTAYTMQAGQSRFSV
                     WFDLTNLKVSDYSISVSVPDKEKAFSGSSAPIHFDGKPTKNTPETEQKNSNPVPANNQ
                     PKPAASGRVTSTEQPQNVPSATASANHMTRTNHRSDKVLKASSSNTPSAAKSIDSAEK
                     GKGMLSDSTAQDKEQKGFPWLLSSLIAITAAALLALVIKAVHRK"
     gene            6664..7410
                     /gene="rlmB"
                     /locus_tag="TV188_001155"
     CDS             6664..7410
                     /gene="rlmB"
                     /locus_tag="TV188_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEL1534517.1"
                     /translation="MKAKEINETKDIVYGVHAVTESLLANTGNKLYIQEDLCGKHVDH
                     IKDLATSKKVSISWTKKKALTEMTAGAVHQGFALRVSAFAYTELDELLELAQQEDNPL
                     LLILDGLTDPHNFGSILRTADATGVCGVIIPKHRAVGVTPVVAKTSTGAVEHVPIARV
                     TNLSQALDQLKANGFWVFGTDVTGTPSYKWNTSGKLALIIGNEGKGISANIKKQVDEM
                     ITIPMMGHVQSLNASVAAAILMYEVFRNKL"
     gene            7411..7929
                     /locus_tag="TV188_001156"
     CDS             7411..7929
                     /locus_tag="TV188_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HEL1534518.1"
                     /translation="MKKRLLLVDGYNMIAFWESTRQFFKTNQLDQARRILLNKLNNYA
                     HFDDSDIICVFDAQYVPGLRQRYDQYRISVIFTEEEETADSYIERTAAELNTALTMVE
                     VATSDLNEQWTIFSQGALRVTAKELEQRVNAVKSDLDKLSQDIDLKKPRLGPFDQGQL
                     NQLKDFMNRLDD"
     gene            8113..8973
                     /locus_tag="TV188_001157"
     CDS             8113..8973
                     /locus_tag="TV188_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1534519.1"
                     /translation="MTFVLMTDSTADLDSFWAKEHNIDIVGLTVECDGKVYKTVGPDR
                     LTSDALLAMMKSGSQPKTSQINVGQFEEIFRHYAADNQALLYIAFSSVLSGTYQSAVM
                     ARELVLEDYPDAVIEIVDSLAAAGGEGYLTMLASEARDNGKSLLETKAIIEGILPRLR
                     TYFLVDDLFHLVRGGRLSKGSAFIGSLVNIKPLLWIDASGKLVPIAKIRGRKKAIKEI
                     ADRATKDIADSTVVVSYTSDQTGADDLREQLLAHEGISDVFMLPLGPVIAAHTGPDTL
                     AVFVIGKEKR"
     gene            9512..9958
                     /gene="rplM"
                     /locus_tag="TV188_001158"
     CDS             9512..9958
                     /gene="rplM"
                     /locus_tag="TV188_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEL1534520.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKVYYTHSMYPGGLKSITAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGGEHTHAAQQPEVLDISGLI"
     gene            9978..10370
                     /gene="rpsI"
                     /locus_tag="TV188_001159"
     CDS             9978..10370
                     /gene="rpsI"
                     /locus_tag="TV188_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEL1534521.1"
                     /translation="MAQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTEGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(10485..11576)
                     /locus_tag="TV188_001160"
                     /pseudo
     CDS             complement(10485..11576)
                     /locus_tag="TV188_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378871.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(11630..12148)
                     /locus_tag="TV188_001161"
     CDS             complement(11630..12148)
                     /locus_tag="TV188_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1534522.1"
                     /translation="MTNNIAKLIEESGKKIKSISEALDISYPTLSSYNQGIRKPKKEN
                     AQKLADYFGVSVAYILGIDEEKYAPSNLKIVTDSFKTSEITSVTPFKSDMEKLKKGIE
                     LGEIHLSMPLNEVFSDDFRRILSNYLMDYEETFIKDLIKFMNNQGQKSDIWKTWIQTE
                     EFQIRRADRDRK"
     gene            12301..12585
                     /locus_tag="TV188_001162"
     CDS             12301..12585
                     /locus_tag="TV188_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1534523.1"
                     /translation="MSEEATLVVQLPKVLEKQLRAHYDEMVSTAIERALEDKELYKPM
                     VRMAALSRWLDVSTTTLQKWTREGMPTMVIDGVTLYDKRAVTRWLKQYER"
     gene            12594..13079
                     /locus_tag="TV188_001163"
                     /pseudo
     CDS             12594..13079
                     /locus_tag="TV188_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643974.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
     gene            13131..13418
                     /locus_tag="TV188_001164"
     CDS             13131..13418
                     /locus_tag="TV188_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HEL1534524.1"
                     /translation="METLWHRELTQQEKVLLEGFAVNDSLLQLAIQKTEELEPKKQNM
                     SYVKGILMNWEARGFITVDQVIASEEDYRPLEIANVEVSEDFLAAMDIWKD"
     gene            13433..13723
                     /locus_tag="TV188_001165"
     CDS             13433..13723
                     /locus_tag="TV188_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534525.1"
                     /translation="MTVYYQLENMLVAGFKSQDEYDRYQALKRDYEGESEDYSFSIRE
                     ITNQLEIICQTSENDFPNLSEALMIDYLELVGELKRYDTNQADRYLGMVRHV"
     gene            13716..14078
                     /locus_tag="TV188_001166"
     CDS             13716..14078
                     /locus_tag="TV188_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1534526.1"
                     /translation="MSERIRTILKKFYVTELQNEVLNQLVNDTGLQTFSNYARRMLFK
                     ETSLFMRFDESQFDELIYSLRRIQNNLRQLSKIAEQSQDSQAYRAMDYSRRLVSHYEK
                     QLTRYHKKKKRKLLSKGA"
     gene            14078..14434
                     /locus_tag="TV188_001167"
     CDS             14078..14434
                     /locus_tag="TV188_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1534527.1"
                     /translation="MDKRRIRNVIKQVFLSEEENQKLLEKMKQDGFTNFSLFARKQLL
                     KPDFETWLVSFPEYQPLTGRLLSVGRTINGIAKSATQFGKISQHDLMELGQLMEELVE
                     LVEKQVKEDKQRIAKK"
     gene            14778..16322
                     /locus_tag="TV188_001168"
     CDS             14778..16322
                     /locus_tag="TV188_001168"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HEL1534528.1"
                     /translation="MSEQAQRQELHRKIWAIADDVRGAVDGWDFKQYILGILFYRFIS
                     ENFKTYIEGGEDFNYEEIPDEVITPEVKDDAIKTKGYFIMPAQLFSNVVKTARSNDNL
                     NTELKDIFDAIEASAMGYASENDIKGLFDDVDTRSNKLGSTVPERNERLALILEGIAS
                     LDFGSFEDNHIDLFGDAYEFLISNYASNAGKSGGEFFTPQSVSRLLARIVMLGKDEKN
                     KINKIYDPACGSGSLLLQAKKQFTEHIIEDGFYGQEINMTTYNLARMNMFLHNINYDK
                     FSIERGNTLLDPKHGNDKPFDAIVSNPPYSIKWVGSDDPTLINDDRFAPAGILAPKSK
                     ADFAFIMHSLSYLSNKGRAAIVTFPGIFYRGGAEQKIRQYLVDGNFVETVIQLPDNLL
                     FGTSIATCILILAKNKPTTDVLFIDASQQFKKETNNNVLTEENIEKILKSVEHKNNEE
                     YFAQLISQEKIVEADYNLSVSTYVEKEDTREKINIDVLNKEIAETVKNIDRLRAEIDK
                     IVEELS"
     gene            16324..17586
                     /locus_tag="TV188_001169"
     CDS             16324..17586
                     /locus_tag="TV188_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002892408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1534529.1"
                     /translation="MTYIDEMIKELCPDGVEWKELGEVVDYEQPTKYIVKSKEYSDDY
                     SIPVLTAGQTFILGYTNEVTGIYPASKEHPVIIFDDFTTARKWVDFEFKVKSSAMKLL
                     SIKSDRQDDVSIRYVWHYLGTIKYTPEQHARQWIGTFSKFKIPLPPLEIQGEIVKILD
                     KFTEHVTELTAELTAELTFRQKQYSYFRDKLLSFDDESMGGANDKVYTVQWKTLGEVV
                     NFRRGSFPQPYTDMSFYGGEDAQPFVQVVDVADEGFRLNTKTKKTISQKAIPKSVFVP
                     KGTVIVTLQGTLGRVAVTQYDAYVDRTLAIFDGYKQEVDKRYFAHQLKFIFDREKEFA
                     RGSTLKTITKQEFSNFKIPVPPLDIQRRIVQVLDNFDTVCNDLNIGLPKEIELHQKQY
                     AYFRDKLLTFTAEGVYTDSTVQYSTDKT"
     gene            17595..18200
                     /locus_tag="TV188_001170"
     CDS             17595..18200
                     /locus_tag="TV188_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1534530.1"
                     /translation="MTWVFGPIKVELGAVCDVVRGNGLQKKDFVNEGYPVIHYGQIYT
                     FYGLSARVTKSFVSPEVGQKLKKAKTGDVIVATTSENIEDVGKALVWEGAEDVCIGGH
                     SCVLHTEQNSKYLLYYFQTTVFQKQKEKLVIGTKVIELYPKNLEKAIIILPPVYEQGR
                     IVSILDKFDTLTSDLTQGLPKEIEQRQKQYEYWRDLLLNFP"
     gene            18215..19423
                     /locus_tag="TV188_001171"
     CDS             18215..19423
                     /locus_tag="TV188_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1534531.1"
                     /translation="MGNDIKFENLEQISDNIISSNKKVHLLYAYNATGKTRLSMELKN
                     KVNETDSDGNSIKHILYFNSYTEDLFTWDNDLENDEDRYLIYDKRTYFGNFLEEQQLF
                     ERAVDNFQKYVGRSIDIEFQDVIETVKDEFGNVQKDNRGEALTISNKKSIRFKVDGHT
                     IKVSRGEERIFVWSVFLTLLEIIIEDLTESADTSEFSKMNYIYIDDPISSLDDTNIIN
                     AAIYLSDVIGSAENTDLKFVVSTHQALFYNVLYNEIRFDRRIKKKVFYVMKATDEIED
                     EKQFKYLLTDVEGDSPFGYHLRVREELRKAIQDEQVEKFHFALFRNLVEKTATFLGYG
                     RWENILLGLDVAGHVITSENIKLYTQLIDLYTHNRHADLEYRELPPQEKNTLINLFNS
                     FDSIYRFKED"
     gene            19426..22521
                     /locus_tag="TV188_001172"
     CDS             19426..22521
                     /locus_tag="TV188_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019771596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HEL1534532.1"
                     /translation="MTEIIQTDTILEAKNFIVLEKYTKLEKPSTYQTEADLERELVSD
                     LRQQGYEYLNNLTTPEALLDNLKTQMEALNGVVFSEAEWLRFLEEYLNKPSDGLIDRT
                     RKLHDNHIYDFIFDDGHIQNIYLWDKKNISRNKLQVINQMSQVGTSSNRYDVTILVNG
                     LPLVQIELKKRGVAIREAFNQVHRYSKESFNEENSLFKYLQIFVISNGTDTRYFANTT
                     KREKNSFDFTMNWALKNNEPIKDLKDFTATFFSQQTLLNILINYSVFDTSDTLLIMRP
                     YQIAATERIIWKIRSAIDSKIKSGPETGGYIWHTTGSGKTLTSFKAARLATEMDKVDK
                     VFFVVDRKDLDYQTMKEYQRFSPDSVNGSNSTAGLKRNIEKDDNKIVVTTIQKLNNFM
                     SSEAQHEIYNKQVVFIFDECHCSQFGEAQKRLKQKFKKYCQFGFTGTPIKVENALGSE
                     TTASVFGRELHAYVITDAIRDQKVLKFKVDYNDVRPQFKSLETEQDLGKLSAAENKKA
                     LLHPTRITEISAYILEHFNQKTHRQNGKGFNAMFAVSSVEAAKAYYQELQDQQAGKAK
                     PLKIATIFSYAANEEQAAIGEIDDETFSPADLSDISSKEFLSGAISDYNRLFQTNFSI
                     NGNEFQNYYRDLAKRVKSGEVDLLIVVGMFLTGFDAPTLNTLFVDKNLRYHGLIQAFS
                     RTNRIYNATKTFGNIVTFRDLEKATTDAIKLFGKTETADILLERSYEDYMNGYIEAGQ
                     EQKGYLEVVKELQERFPDPTTIIKESDKKEFVTLFGQFLRLDNILQNYDDFMSLQALQ
                     ELDVTDIEALADFKGRFHLDDEAVAVLSQLDIPSVREIQDYRSAYNDIKSWYDNERRN
                     QQNNDSEIDWDAVVFEVELLKSQEINLDYILELIFETNQKVSDKDQLIEEITRTIRAS
                     LGQRAKESLIVDFINASDLDSFSEKSDILEQFYTFARQKQKEAVANLIETEGLNVESA
                     SRYIQMSLKREYASENGNALNEALPKMSPLNPQYRTKKQMVFEKIVDLVEIFKGIGGE
                     I"
     gene            22689..24140
                     /locus_tag="TV188_001173"
     CDS             22689..24140
                     /locus_tag="TV188_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014293901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1534533.1"
                     /translation="MENKKDLIQTLAYYQFSLENQYLDRKSARKKPQELLKHLIAFAN
                     ADGGQLVIGIEDEKQDNIITGFKDGRAYPIDDFKKIDHEMRETPLDLSLEEIPVLNHK
                     GEDDLILVISVELSSNRVIAAPNDEVYLRQGDESVKLSYEQRTQLSYDKGQRFFEDEV
                     VPDATLEDIDDGLVQDFKNRFDISERSMEEVLKARRFLVNGKLTKAAILLFAKYPSAF
                     FPQARVRFQRFDGTDMGTGSSFNVIKEVTFDDALPTLIIKVRDFIRTQLREFQYLDDN
                     GQFQILPEYPEFAWFEGVVNAVTHRDYSVYGDHIRVLMFDDRLEIHSPGKLPNIVTVD
                     NIKHECFSRNPRIARTLTEFGWVREMNEGVKRIYSEMESAFLHEPKYLEPGNKVVLTL
                     ENNIVSRHLRTRDSLEKQFSDFGNLTADEQAIVHYMYNSGDKMTTAKAIELTGRSRSF
                     VVKMLHHLRDLEIITWFGSSKNDRNQYYLLVDK"
BASE COUNT         7400 a         4268 c         5490 g         7072 t
ORIGIN      
        1 aggcaggtct ttttttgctg cgtcatcagc ggcttagcgt gcttggctgt agggctatag
       61 tgataaaaga gagtgctgct ggtattgaca gccctttcaa actttttcta ggaatgcctt
      121 ttagggtcgt gaatttttaa ctattttatg gtaaaatgta gcagatacgt cgtttgatac
      181 aaagaggagt gtgtaattcc ttacagattg ctctttgtag caaaacaacg tatagccata
      241 aaaaataaaa ggctagcaag ctttggtcgg gtcaaacggc tatggtaggc tagctcgttc
      301 aaggagaaag aatgtcaaaa caaacattta caacaacctt tgcaggcaaa ccacttgttg
      361 ttgaggtcgg tcaagtagcc aagcgagcaa atggtgccac tgtcgttcgt tatggggagt
      421 ctacagtgct aactgctgct gtcatgtcta agaagatgtc aacaggagac tttttcccgc
      481 ttcaagtcaa ttatgaagaa aaaatgtatg ccgcaggtaa atttcccggt ggctggatga
      541 agcgtgaggg acgtccgtca acagatgcga ccttaaccgc tcgcttgatt gaccgcccta
      601 tccgtcctat gtttgctgag ggctttcgta atgaggtcca ggtgattaat actgtcctgt
      661 cttatgacga agatgctagt gcccctatgg ctgctatgct tggtagctca ttagccctat
      721 cgatttcaga tattcctttt aatgggccga ttgctggtgt tcaggtggcc tatgttgagg
      781 gtgaatttat catcaatcct gataaggccc agcaggaggc ttcattatta gagttaaccg
      841 tagcaggaac aaaagatgcg atcaatatgg ttgaatctgg tgctaaggaa ttgccagagg
      901 ctattatgct agaagcactt ttggttggcc ataaggctat acaggagttg attgcttttc
      961 aagaagagat tgttgcagcg gtgggcaagg aaaaggctga ggtagagcta ttacaggttg
     1021 ctgctgattt gcaggctgag atcatagaga cttacaatgc tgatttgcag caggctattc
     1081 aggttgagga gaaaaaagca cgtgaagccg caaccgaggc tgtcaaggag cgtgtcatag
     1141 ctgcatacga ggagcgttat gcagcagacg aagagcatga ccgtatcatg cgtgatgtgg
     1201 ctgaaatttt ggagcaaatg gagcatgctg aggttcgtcg cctcatcact gaggataagg
     1261 ttcgtcctga tggtcgtcgt gttgatgaga ttcgtccgct tgctgctgag attgatttct
     1321 taccaagggt gcatggctca ggcctcttta cgcgcggtca aactcaagct ttgtctgtct
     1381 tgactctagc cccaatggga gatactcaaa ttattgatgg gcttgagcct gagtacaaaa
     1441 aacgcttctt gcaccactat aatttccctc aatattctgt tggtgagaca ggccgctacg
     1501 gtgcagcagg gcgtcgtgaa attgggcatg gtgctttagg cgagcgcgct cttgcacaag
     1561 tccttccaag ccttgaggca tttccatatg ctattcgtct agtggctgag gtattggaat
     1621 caaacggttc ttcctcgcag gcctctatct gtgcagggac gcttgctttg atggctggtg
     1681 gtgtgccgat caaggcaccg gttgcgggta ttgctatggg acttatctct gatgggacca
     1741 attatactgt tttaacagac attcaggggt tagaggatca ttttggcgac atggacttca
     1801 aggttgctgg gacacgccaa gggattacag cactgcaaat ggatatcaag atcgaaggta
     1861 tcacccctca aatcctagaa gaagccttgg cgcaggctaa aaaggctcgc tttgaaattc
     1921 ttgacttgat tgaggcaacc attgctgagc ctcgtccaga attggcacca acagcaccaa
     1981 agattgatac catcaagatt gatgttgata agattaaggt ggttattggt aagggtggcg
     2041 aaaccattga taagattatt gctgagacag gtgttaagat tgacattgat gaggaaggaa
     2101 atgtttcaat ctactcaagt gatcaggacg ctatcaatcg tgctaaggaa atcattgcta
     2161 gcctagtacg tgaggctaag gtaggagagg tctaccatgc taaggttgtc cgtattgaaa
     2221 aatttggtgc ctttgttaac ctctttgaca agacagatgc gctggtgcat atctctgaaa
     2281 ttgcttggag ccgcactacc aatgtctcag atgttcttga aatcggtgaa gaggttgacg
     2341 ttaaggttat taaggttgat gataagggac gtattgacgc atcaatgaaa gccttggtgc
     2401 cacgcccgcc aaagccagaa aaatcagaag caaaaaaaga aggcaaacat gactaataca
     2461 aatgaactag atattcgttt aagagccttt atcaatgccc ctgataattt tttagatagc
     2521 gtggccttgg ttaatgcttt tcaccagtat ccggtgtggg cagcaaaaaa gccctatgct
     2581 attgagattg aaggggtaag gatttttcct gtattcacag ataaggacga catggcgacc
     2641 tttaaagagg agcaaaagag tgcacaagct cagtattggg tagagcgctc tgctcttact
     2701 gtcttggagg aggctgttca tgcaggtgct gctgggctag gctttaatct caagaaaaag
     2761 ggagattttg gcaattctac agtgttcaag tctgctgata tgattcagtt tatgaacaat
     2821 tacacaacga ttttgaatac cttgatgagt gatgacaata gcgcagcaga taccctggat
     2881 aggctttatc tggtgccggc ctttgtttac cctaaggaag aggagcatta ctatgacagg
     2941 ctttttccaa ccatgtcaac tccagagggg aagcgttatg ttcctgcctt ttcaaatctt
     3001 cagagcttcg ctaaatggta caatcaagag gagtttggcg gcctttttag gaaatcaggt
     3061 ggtgttatct taacatggaa gatagcagac atttatcagc caagaaatgg caataatgac
     3121 atagacgaga cctttggggt tgctattgac ccctttgatg atcagcagat tcttgttgat
     3181 tggtctgata ttgacacata aaaggagttt aaatgggctg gtggaaggac aatattgata
     3241 ttgtaaagca actagatcct gctgcacgta gcaccctaga ggttatccta acctaccctg
     3301 gattaaaggc cttggcagcg cacaggctgt cacatttttt gtggcagcat ggctttaagc
     3361 tgctggctcg aatgcatagc cagttttggc gattttggac acagattgaa atccacccag
     3421 gagctaggat tgcttcaggt gttttcattg accatggggc tggcttggtg attggtgaga
     3481 cggccattgt tgaaaaagga gccatgcttt atcatggagt gacgcttggt ggaactggaa
     3541 aagatcgagg gaagcggcac cctactgttc gtgagggggc actgatttct gcccatgctc
     3601 aaattatcgg tcctgtcgag attgggaaat cggctaaggt tggagctgca gctgttgtgt
     3661 tgactgatgt acctgctggc gtgacggtcg ttggcattcc agcccaaatt gttcgagtgc
     3721 atgagaaaaa gccctcaagg caggattaat agttttctct agaggcagtc agccaaaaaa
     3781 cgggagagtt agagccctat gcttacctca gttgctgaca gcttgcgcag tctaggagaa
     3841 aaggataaaa acaaaaggga aaagtgatga taaaaatcta tgataccatg accagaagtc
     3901 tgcgagagtt tgtaccaata actgataagg tggtcaatat gtatgtctgc gggccaacgg
     3961 tttacaatta tattcacatt ggcaatgcac gttcggctgt ggcctttgat acgattcgtc
     4021 gctactttga atacgcaggc tatacagtca attacatttc aaattttaca gatgtagacg
     4081 ataagattat caaggcagcc aaggaatcag gtgtatcacc caaggaattg gcggacagat
     4141 ttattgctgc ctttatggag gataccaagg cactcggtgt gaagccggcc accaaaaatc
     4201 cacgcgtcat ggactatatg gacgagatca ttgcctttat cgctgcttta atcaaaaaag
     4261 gctatgccta tgagtcggca ggtgatattt atttccgcgt ggcaaaggca tcaaattatg
     4321 ccagactggc taataaaacg attgctgatt tggaggctgg tgctagtggt cgtacagata
     4381 ccgaaactgc tctcaaggaa gatcctttgg actttgccct atggaaatca gcaaagctag
     4441 gcgagatttc ttgggcaagt ccttggagcg ccggtcgtcc tggctggcat atcgagtgct
     4501 ctgtaatggc aaccgagctt ttgggagata ccattgatat tcatggtggt ggcgcagacc
     4561 tggaattccc acaccatacc aatgaaattg ctcaatcaga agcaaaaact agcaaaactt
     4621 ttgccaatta ctggatgcat aatggctttg ttaatgttga caacgaaaaa atgtctaagt
     4681 cactgggcaa ctttgtgact gttcatgatc tgctaaagac ggtggatggg caaacgctac
     4741 gctttttctt ggctactcag cattatcgta agccgattaa ttttactgaa aaagctattc
     4801 atgatgctgg agttaacctc aaatacttga aaaacacgct tcagcagccc acagtagcca
     4861 ctgcagatgc tagccagctt gctgccttta tcactgcctt caaagcagcc atgaatgatg
     4921 attttaatac agcaaatggg attacagtct tatttgacat ggcaaaatgg attaactccg
     4981 gcgcctattc tgaggctgtc aaatcagcat ttgaagagat gctagctgtt tttggcattg
     5041 tctttgaagc agaaagccta gacacagaga ttgagcagct gattgctgag cgtcaggagg
     5101 cacgtgccaa tcgagatttt gcaagggcag atgctattcg ggatcagttg gcagctcagg
     5161 ggatcaagct gttggataca aaagaaggtg tgaggtggat acgtggctaa ttcagttgat
     5221 gtcaatttga ttaatggcat tgcccttgcc tttgttggtg atgctgttta ttcttactat
     5281 attcgtcgtc atctgatttt ccaaggccag accaagccaa ataagctcca ctaccttgca
     5341 acaaaatatg tttctgcaaa ggcacaggct tctctgattc aggccatgct agaagcacaa
     5401 ctattgaccg aaaaagaaaa agacatctac aaacgaggcc gcaataccaa cagccatacc
     5461 aaggctaaaa atgctgatgt agtaacctat cgtatgtcaa caggctttga agctattatg
     5521 ggctaccttg atatgacagg tcagacagaa cggctagaac tgttgatcca gtggtgtatc
     5581 aagcaggtgg agaacagtcc tcaatcataa tgatgaatca tctaaaacat tctctgtgtc
     5641 actagcgatc tgccatcgct caaagtcatg agagtgtttt tatgttgtgt ttaaaagtta
     5701 tgtcacaata tagatacaca cgaaacataa aataaatatt tgtaacaaaa acgtaacaaa
     5761 actattgaaa aattttccga atagtttata atgaaagagt cataataaaa tgataggaga
     5821 atgtctatga aaccaatgag aaacgtagcc ttagttattt cagcaatgtt actgttaagc
     5881 tcacaggcct ttgtatcagc agtagcagca caggacaatc aaccaaccat agcagttcaa
     5941 gcacaggcag cagctgaggc caatgtcagt gctcgtatgc gttcagatca gcccgttatt
     6001 gaagctaaca ttgctaccag tcagccagtt agccaaagca ctgaggctac tattttacta
     6061 aaggatgcca aaggcaacgc gattaatagc acagcctata ccatgcaggc tggtcaaagc
     6121 cggttttcag tatggtttga ccttacgaac ctaaaggtta gtgattatag tatatcagtg
     6181 agtgttcctg ataaagaaaa ggcctttagt ggtagctcag cacctattca ttttgatgga
     6241 aagccaacca aaaatacccc agagacagaa cagaaaaaca gcaatccagt accagctaat
     6301 aaccagccta aacccgctgc tagcggcagg gtgacaagca ctgagcaacc ccaaaatgtg
     6361 cctagcgcga ctgctagcgc caatcatatg acaagaacca atcatcgatc tgataaggtc
     6421 ctaaaggcaa gctcaagcaa cacaccatca gctgccaaat caatagactc tgctgagaaa
     6481 ggcaagggca tgctttctga tagcacagcc caagataaag agcaaaaagg ctttccttgg
     6541 ctgctatcat ctctaattgc aattacagca gctgctttac ttgctcttgt catcaaagct
     6601 gttcacagga aataaaaaga gcagcaagag ctattttatt gctttcgtgg tataataaaa
     6661 accatgaaag ctaaagaaat caatgaaacc aaggatattg tttatggcgt ccatgccgtt
     6721 accgaaagcc tactagccaa tactggaaat aagctttaca ttcaagagga tctgtgtggt
     6781 aagcatgttg atcacatcaa ggatttagcc actagtaaga aggtgtctat ctcttggaca
     6841 aaaaagaaag ctttgaccga aatgacagca ggagctgttc atcagggctt tgcgcttcga
     6901 gtgtcagcct ttgcttatac tgagctagat gagctgctag agctggcaca gcaggaggat
     6961 aatcccttgc tgctcatcct agatgggctg acagatcctc ataattttgg gtctatttta
     7021 agaacagccg acgcaacagg tgtttgtggt gtgattatcc ctaagcatcg tgctgttggt
     7081 gtgacaccag tggttgctaa gacctcaaca ggagctgttg agcatgttcc aattgctcgc
     7141 gtgacaaatc ttagccaagc attggatcag ctaaaagcaa atggcttttg ggtcttcggg
     7201 acagatgtaa ctggtacacc atcatacaag tggaatacct caggcaagct ggctttgatt
     7261 attggcaatg agggtaaggg catttcagct aacatcaaaa aacaggtaga tgaaatgatt
     7321 accattccta tgatgggtca tgttcagagc ttaaatgcta gcgttgcagc tgctattttg
     7381 atgtatgaag tatttagaaa taaattatag atgaaaaaaa gactattgct ggttgatggc
     7441 tataacatga ttgccttttg ggaatcaact cgtcagtttt ttaagacaaa ccaattggat
     7501 caagctagaa ggatcttgct aaataagctg aacaactatg cgcattttga tgatagtgac
     7561 attatttgcg tatttgatgc tcagtatgtt ccaggactta gacagcgtta tgaccaatat
     7621 aggatttctg ttatttttac cgaagaggaa gaaacagctg atagctatat tgagcggact
     7681 gctgctgagc taaacaccgc tctaaccatg gtagaggtgg ctactagtga tctgaatgaa
     7741 cagtggacga tcttttccca aggcgccttg cgtgtcactg ctaaagagct tgagcagcgt
     7801 gttaatgctg ttaagtcgga tttagataag ctgtcacagg atattgatct taaaaagcct
     7861 agactgggtc cctttgatca agggcagctt aatcagctca aggactttat gaatcgatta
     7921 gatgattaat aagcttatct tgctagcttt tctaggtatg attctccagg ctgctagagc
     7981 agctcatacg atctaacggt gatcatttct gaggcagctg gttcttattg ctttcttagc
     8041 tgatattttt ttgttatact atgagaaaat catttgatta ttaaacgata atgacgttac
     8101 ttgggagttc agatgacatt tgtattgatg acagattcaa cagcggattt agattctttt
     8161 tgggcaaagg agcataacat cgatatagta ggcctaactg ttgaatgtga tggcaaggtt
     8221 tacaagacgg ttggtccaga tagattaacg agtgatgctt tgctagctat gatgaaaagt
     8281 gggagccagc ccaaaacaag ccagataaat gttggtcagt ttgaagagat ttttcgacat
     8341 tacgcagctg ataaccaagc tcttttatat atcgcctttt cttcagtcct atcaggtacc
     8401 tatcaaagtg ctgtcatggc acgtgagctg gttttggagg actatccgga cgctgtaatt
     8461 gagattgttg atagcttggc tgcagcagga ggagagggct atttgaccat gctagcctcg
     8521 gaggcgcgtg ataatggaaa aagcctatta gaaaccaaag cgataataga aggtattttg
     8581 cctcgcttac gcacctattt cttagtagat gatctttttc atcttgtgcg aggaggacgc
     8641 ttgtcaaaag gctctgcttt tataggcagc ctagtgaata ttaagcctct cttatggatt
     8701 gatgccagcg gaaaattagt tcctattgcc aagattcgtg gccgtaaaaa ggccattaag
     8761 gaaattgctg acagagccac aaaagatatt gctgattcaa ctgttgttgt gtcctatact
     8821 agtgatcaga ctggggcaga tgacctacga gaacagctat tagcacatga aggtatcagt
     8881 gatgtcttta tgctgccgct cggaccggtg attgctgctc atacaggtcc agatacctta
     8941 gcggtctttg tcatcggcaa ggaaaaaaga taaaaagaaa aggattgaag cgcttgtttc
     9001 aattcttttt tgtcgactat agcttgtttt agctgtgatg ccgcttaaga gtatgggtgt
     9061 tcgcattttt tatttttaat caaaagttag aatgaattgt ttgacaatga aggtgcgcgt
     9121 gcaggtaagg aactagcata acagaacagg gctttttgat ttgccagaag tcagatgtca
     9181 aatgttttag cagttgacag gagctttggt cattccacca ctaatctttg tattgttatt
     9241 tgcataggag ctaacaggaa ctgagcggat tttttggagg gaagtcaagg ctaatagtcc
     9301 agctcaaaag caagcctgtt cttcttgtga aaaagcaaaa ataatcaaag aaatagagct
     9361 aaaccacttg actatcagtt aagaagtttg atactatagt agacggtatt gtttacccca
     9421 tttgaaaggc cccggaacct tccaaatacc ttcgatggac cggaacatcc atcactaatg
     9481 taaacaaaaa cgaattcgta taggagaaat catgaacaaa acaactttca tggctaaacc
     9541 aggccaagtt gaacgcaaat ggtacgttgt tgacgcaaca gatgtgccac ttggacgcct
     9601 ttctgcagta gttgctagcg tacttcgcgg aaagaacaag ccaactttca caccgcacac
     9661 tgatacaggt gactttgtta ttgttatcaa tgctgagaag gttaaattaa ctggtaaaaa
     9721 agcaactgat aaggtttatt acactcactc aatgtaccca ggtggcttga aatcaatcac
     9781 tgctggtgag cttcgctcta aaaatgccgt tcgtttgatt gaaaagtcag taaaaggcat
     9841 gcttccacac aacactcttg gacgtgcaca aggtatgaaa ttaaaggtct ttgttggcgg
     9901 tgagcacact catgctgcac aacaaccaga agtacttgat atttcaggac ttatctaaga
     9961 gaaaggagca ttaaataatg gcacaagcac aatatgcagg tactggtcgt cgtaaaaacg
    10021 ctgttgcacg cgttcgttta gttccaggta ctggtaaaat cactgttaat aaaaaagatg
    10081 ttgaagaata catcccacat gctgacctac gtttagtcat taatcagcct tttgcagtga
    10141 cttcaactga aggctcatac gacgtttttg ttaacgttgt aggtggtggt tatgctggtc
    10201 aatcaggtgc gattcgtcat ggtatcgctc gtgcgcttct tcaagtggac ccagatttcc
    10261 gtgactcact aaagcgcgct ggtcttctta cacgtgacgc acgtatggtt gaacgtaaaa
    10321 aaccaggtct taaaaaagcc cgtaaagcta gccagttctc aaaacgttaa tatccagtta
    10381 taccaacgtt tcagagcact ttgcgaagtt ttcgcaaggt gcttttttgt tgaaaaaagc
    10441 accttggtaa tctgttgaga cctagtttta agagaggtta agttagaatg actataagta
    10501 tctaaagtca tctggctgct agcatgacct agacgcttag cggtattaac tgggtcaatt
    10561 cccatttcaa tcatcaaggt tgcgtgagtg tgcctaaacc catgtgggct aatcttttta
    10621 agattatgct ttcgtataat gcgttttaga atattgttga tatagtcagc gtgtaagggt
    10681 tctatctcac catctctgtt gcagtatgta aacataaatt ctttgtcgag agaaaggggc
    10741 tgtactgata attgcccctt ttctttgcta gtttcctgtt tccatttgtt gaggatagaa
    10801 caggtttcat catcaagata gatagagcgt actgagaatg tatttttagt tcctttttca
    10861 atggcatgac catctattct tcctaaactt ttgctgactg ttaatagttg attctcagaa
    10921 tcaaaatctt cccatttgag ggcgtagagc tctccttttc gtaacccgct gtatgctagt
    10981 aatcgaaata gagcataatg tttataaggt tcattttcta aaatgattgt caaaaaatga
    11041 tgcaactcgt taactgtcca gtagttctca ctgacagttt ttttgagttt aggcataata
    11101 actttgctca taggattacg ttcaatatga ttcatattga tggcaaattc aaaggtttta
    11161 gaggtgtatg acttgatttg cttcatgttc ttgaatgatt tcgctttatc tgtgataaag
    11221 gtttggcagt ctagcggact gatttttgaa atctttttct ctccaaaggt tggaagaata
    11281 tgaaggcgat ataaatcggc cgttttagct gcagtagttg tttcaacggt atctttgtaa
    11341 gcttcatacc acctttgata tagttcttgg taagtatagg ttgtttgagc agtaagatgg
    11401 gcaaaagttc cactattcag ctgatgatta acagcagttt catgagcttt ggcagcttta
    11461 cgcgtcttga atcctcgttt agtgtaatat tttttcttac cgtagtcgtt tagaccaagg
    11521 taaactttaa caaaataggt aattcctttt gtagattggt atttgtgtac agacataaca
    11581 gttctccgtt tctaagtttt cggagcttat gtaattgaga aatattagtc tattttctgt
    11641 cacgatctgc tcgtctaatt tgaaactctt cggtttgtat ccatgttttc caaatatccg
    11701 atttttggcc ttggttattc ataaacttaa ttaagtcttt gataaaggtt tcttcataat
    11761 ccattaagta gttagaaaga atacgtctaa agtcatctga gaaaacctcg tttaagggca
    11821 tagacaaatg aatctctcct agttcgattc ctttcttaag cttctccata tcgcttttaa
    11881 aaggtgttac agaagtaatt tcagatgtct tgaaactatc agtgacgatt tttaaatttg
    11941 acggagcgta cttttcttcg tcaattccaa ggatgtatgc cactgagaca ccaaaataat
    12001 ccgctaactt ttgagcattc tcttttttag gttttcgtat tccttggtta tagctagata
    12061 gtgttgggta ggatatatct agcgcttcac tgatactttt tatttttttg ccactttctt
    12121 ctataagttt agctatatta ttagtcatag attcctccta attgatattc taccacattt
    12181 aatacaaaaa gtataatacc acttgacaag aatacaaaaa gtatttataa tttaaaatgt
    12241 ataataaaat atacaaattt cggagtttat ttaattgaga aatggaaacg aggtaatgat
    12301 atgtctgaag aagcgacttt agttgttcaa cttcccaaag ttttggaaaa acaattaagg
    12361 gcacattatg atgaaatggt ttctacagct attgaaagag cgctagagga taaagaatta
    12421 tataaaccta tggttcggat ggcagccctt tctagatggc ttgatgtgtc aacgacaaca
    12481 cttcaaaagt ggacgcgaga aggaatgcct acaatggtta ttgatggtgt gactctgtac
    12541 gataaacgtg cggttacacg ttggttgaag caatatgaaa gatgaggtaa agaatggcta
    12601 atagacgaat gttgagtaaa acggtggtgc agatacaacg atttttacgc ctaccacttg
    12661 aagcgcaggc gctttactgt cacttggtag tcaatgcaga tgatgatggt attgttgaag
    12721 cttttcctgt tatgcggatg attaatgcta atgaggacag tttgaattta ttaactctta
    12781 agcagtattt actcttgtta aacaatgaaa tggtttactt tatcaaggat ttctttgagc
    12841 agaataccat caaagcagat cgttacacac cgagtagtca tcgtcaactt cttatagatt
    12901 atctgaagga taatcagttg ttggagtgtc taaatctagg accacgcttg attaattatc
    12961 ttcaaaatac tcggctccaa gttggagcca gtctggatcc agatgggaac cgcaatataa
    13021 ttaaagataa gataagtaaa gataggatag gtaaagataa gttaagtcaa gataagatag
    13081 gattagataa tgatccaatc tcatcacaac tgactgatga catctggtta atggaaacac
    13141 tatggcatcg agaattaacc caacaggaga aagtattatt agaaggattc gcggttaatg
    13201 attctttatt gcagttagct attcagaaaa cagaggagct tgagccaaag aaacaaaaca
    13261 tgagttatgt caaagggata ctaatgaatt gggaagctag agggtttata actgttgacc
    13321 aagtgatagc atctgaagaa gactaccgtc cattagaaat tgcaaatgta gaagtttcag
    13381 aagatttctt agcagctatg gatatatgga aagactaggg gaataatgag ttatgacagt
    13441 atattatcaa ttagaaaata tgttagtggc tgggtttaag tcacaagatg agtacgaccg
    13501 ctatcaggct ctcaagaggg actatgaagg ggagtcagag gactatagct tttcaatcag
    13561 agaaatcaca aatcaacttg aaatcatttg tcagacctca gagaatgatt ttccgaactt
    13621 atcagaagca ttaatgattg attatttaga actggtagga gagttgaaac gatatgatac
    13681 taatcaggca gacaggtatt tagggatggt tcgtcatgtc tgaacgtatc agaactattt
    13741 taaagaagtt ttatgtgacg gaattgcaga atgaagtact taatcaacta gtaaatgata
    13801 caggcttgca aacattctct aattatgctc gtcggatgct ttttaaggaa acatcactct
    13861 ttatgcgatt tgatgaatct cagtttgatg agttgattta ttctttaagg cgtattcaaa
    13921 ataatttaag gcagttatct aaaattgcag agcagtctca agatagtcaa gcctacagag
    13981 ctatggacta tagcagaagg ttagtttcac attatgaaaa gcagttaacg cgttaccaca
    14041 agaaaaagaa acggaaatta ttatctaagg gagcttaatg gataaaagga gaattaggaa
    14101 cgtaattaaa caagtctttt tgtctgaaga agaaaatcaa aaactgttag agaaaatgaa
    14161 gcaagatggc ttcacaaact tttctctttt tgctagaaag caattattaa aacctgattt
    14221 tgaaacttgg ctagttagtt ttccagaata tcagccgctg actggcaggt tactatctgt
    14281 tggtagaaca attaatggca tcgctaaaag cgcaacacag tttggaaaaa tttcccaaca
    14341 tgatttgatg gaattaggtc agttgatgga ggaacttgta gaactggtag agaaacaagt
    14401 gaaggaagac aagcaacgaa tagccaagaa gtgatagtcg ttcagtcatt ttggtagaat
    14461 agttttaaat aaaacaacaa aaacgctgat ggtagtcagc gttttttagc atgtaattgt
    14521 aaaaaatcct tgtacggaca atgtgcggca ccgtataaag tacgggaaat cactaaaaat
    14581 ggagttaggt ctttgcgagc tcagatagtg tatacacact atcgtaaaaa tagaaccatc
    14641 agtaaaggtc agactgacac tttttgattg atgcttatat tttattttgg ggcaaagccc
    14701 caaacccctt gagaaaacgt gtgagaagta gggaaaaatg gtataataga aatattaaag
    14761 actgtgagga tttgaagatg tcagaacaag cacaaaggca agagttgcac cgcaaaatct
    14821 gggcaatcgc agatgatgtc cgtggtgcgg tagatggttg ggatttcaaa caatatattt
    14881 tgggaatcct tttttaccgt tttatcagtg aaaatttcaa gacttatatc gagggtggtg
    14941 aggacttcaa ctatgaggag attccggatg aagtaatcac acctgaggtt aaggatgatg
    15001 cgattaagac aaaggggtac tttattatgc ctgcgcagct tttttccaat gttgtgaaaa
    15061 cagctcgtag taatgacaac ttaaatacgg aactcaagga tatttttgat gccattgagg
    15121 cgagtgctat gggttatgcc agtgaaaatg atattaaagg tctttttgat gacgtagaca
    15181 ccagaagtaa taagctagga agtaccgtcc cagagcgtaa tgaacgctta gcccttatcc
    15241 tagaaggtat tgccagcctt gattttggta gtttcgagga caatcatatc gacctttttg
    15301 gcgatgccta tgagtttctg atttctaact acgcttctaa cgccgggaaa tcaggcggag
    15361 agtttttcac accgcagagc gtgtcacggc tcctagcacg tatcgtcatg ttaggcaagg
    15421 atgaaaagaa caaaatcaat aagatttatg accctgcttg tggttctggt tctctcttgc
    15481 ttcaagccaa aaaacaattt acggagcata ttatcgagga tggtttttat ggtcaggaaa
    15541 tcaacatgac cacctacaac ttggctcgga tgaatatgtt ccttcataat atcaactacg
    15601 acaagtttag cattgagcgt ggcaatacgc tgctggaccc taagcatggc aatgataagc
    15661 cctttgatgc tatcgtgtcc aacccgcctt attcaatcaa gtgggttggt agcgatgacc
    15721 cgacgctaat taatgatgac cgttttgcac cagcggggat tctggcaccc aagtctaaag
    15781 cggattttgc ttttatcatg catagccttt cttatttgtc caataaaggc agagcggcta
    15841 ttgtgacctt ccctgggatt ttttatcgtg gtggagcgga gcaaaagatt cgtcagtatt
    15901 tggtagacgg aaactttgtc gaaactgtta tccaattgcc ggataatctc ctttttggga
    15961 cgtctatcgc tacctgtatc cttattcttg ctaagaataa gccgacaaca gatgttctct
    16021 tcattgacgc tagccagcag ttcaaaaaag aaaccaataa caatgtcttg acagaagaga
    16081 acatcgagaa aattctgaaa agtgttgagc ataagaataa tgaagagtat tttgctcagc
    16141 tcatttccca agaaaaaatt gtggaagctg actacaatct ctctgtatct acctacgtgg
    16201 aaaaagagga tacgcgtgag aagattaata ttgatgtatt aaacaaagaa attgctgaga
    16261 ccgtgaaaaa tattgaccga ttgcgggcag agattgataa gattgtcgag gagttgagct
    16321 gatatgacct acattgatga gatgattaaa gagctttgtc ctgacggagt ggagtggaaa
    16381 gagttgggtg aagtcgttga ctacgaacag ccaacaaagt atatcgtaaa atctaaggaa
    16441 tacagcgatg attattccat tccagttttg acagcaggtc agacatttat tcttggatac
    16501 acaaatgaag taactggtat ttatccagca agtaaggaac atccagttat tattttcgat
    16561 gactttacga cagctagaaa gtgggtggat tttgaattta aagttaagtc ctcggcgatg
    16621 aaactactct ctatcaagtc agaccgtcaa gatgatgttt caataaggta tgtttggcac
    16681 tatttaggaa caataaaata cacaccagaa cagcacgcac gacagtggat agggactttt
    16741 tctaaattta aaatccccct tcccccacta gaaattcaag gggagatagt taaaatactt
    16801 gacaaattca cggaacatgt tacagaattg accgcagaat tgaccgcaga attgaccttt
    16861 cgacagaaac aatattctta ttttagagat aagctcctaa gttttgatga tgaaagtatg
    16921 ggaggggcga acgataaggt ttacactgtc cagtggaaaa cgctggggga ggtggtgaat
    16981 tttaggagag ggtctttccc tcagccttac acagatatgt cgttctatgg tggagaagat
    17041 gcccaaccat ttgttcaagt tgtagatgtt gctgatgaag gatttagact gaatactaaa
    17101 acgaaaaaaa caatttctca aaaagctatt ccaaaaagtg tttttgtacc taagggaacc
    17161 gttatcgtta ccttgcaagg caccctagga agggtagcgg ttacccagta tgatgcttat
    17221 gtcgatagaa cgttagcaat ttttgacggt tataagcaag aagttgataa acgctatttc
    17281 gcacaccaat tgaagtttat ttttgacaga gaaaaagaat ttgctagagg aagtactctg
    17341 aaaacaataa caaaacaaga attctcgaat ttcaaaatcc cagtccctcc tctggatatt
    17401 cagcgtcgta ttgtccaagt tttggataat tttgatacgg tttgtaatga cctaaatatc
    17461 gggctaccta aggagattga gcttcatcag aaacagtatg cctattttag agacaaactc
    17521 ttgaccttca ccgccgaagg cgtgtatact gacagtacag tacagtacag tacagacaag
    17581 acctaattag gctcttgact tgggtttttg gaccgattaa ggttgagttg ggggctgtct
    17641 gcgatgtggt gcgtgggaat ggtttgcaaa agaaggattt tgttaatgag ggttatcctg
    17701 ttattcatta tggacaaatc tataccttct atggattgag tgctcgcgtg acgaaatctt
    17761 ttgtgtcacc agaagttggt caaaaattga aaaaagctaa aactggtgat gtgattgtag
    17821 ctactacttc tgaaaatatt gaagatgttg gtaaagcact tgtttgggaa ggtgctgaag
    17881 atgtttgtat tggtggacac tcttgtgtat tgcacacgga acaaaactcg aagtacttgc
    17941 tttattattt tcagacaact gtgtttcaaa agcaaaagga aaagttagtg ataggaacta
    18001 aagtgattga actgtatcct aaaaatttag aaaaggcgat tattattctc ccacctgtat
    18061 acgaacaagg gcgtatcgtc tccattcttg acaaatttga tacactaact tctgacctta
    18121 cccaaggtct tccgaaagaa attgagcaac gacagaaaca gtatgagtat tggcgggatt
    18181 tactacttaa ctttccgtag gaggaagaat agatatggga aatgatatca aatttgaaaa
    18241 tttagaacag atttcggata atattatttc tagtaataag aaagttcatt tgctatatgc
    18301 ctataatgct actgggaaaa ctaggctttc tatggaattg aaaaataagg taaatgagac
    18361 tgatagtgat ggtaatagca ttaagcacat tttatatttc aattcatata cggaggatct
    18421 ttttacgtgg gataatgatt tggaaaacga tgaagatcga tatttgattt atgataaacg
    18481 aacttatttt ggaaatttcc ttgaagagca acaacttttc gaacgtgctg tagacaattt
    18541 tcaaaagtat gttggtagat ctattgatat tgagttccaa gatgttattg aaacagttaa
    18601 agatgagttc ggaaatgttc aaaaagataa taggggtgag gcactaacaa ttagtaataa
    18661 aaagagtata agatttaaag tagatgggca tacaataaag gtgtctagag gagaagagag
    18721 gatttttgtt tggtcagttt tcttaacgct ccttgaaatt attattgaag atttgactga
    18781 gtctgctgat acctcagaat tttcaaaaat gaactatatc tatattgacg atcctatatc
    18841 ttctttggat gatactaata ttattaatgc tgcaatttat ttgagtgatg ttataggtag
    18901 tgctgaaaat actgatttga aatttgtcgt ctctactcat caagcattat tttataatgt
    18961 actttataat gaaatccgat ttgatagaag aatcaagaaa aaggtttttt acgtcatgaa
    19021 agctactgat gaaattgagg atgagaaaca atttaaatat ttgttgacag atgttgaagg
    19081 ggattctcca tttggatatc atctcagagt gagagaagaa ttgagaaaag caattcaaga
    19141 tgaacaggta gagaaattcc attttgctct ttttagaaac ctagttgaaa aaacagcaac
    19201 atttttagga tatggacgat gggaaaatat cttgttaggt ttagatgttg ctggacatgt
    19261 tataacatct gaaaatatta aactctatac acaactgatt gatttataca ctcataatag
    19321 gcatgctgat ttagaatata gagaattgcc tccccaagag aaaaatactc ttataaattt
    19381 atttaatagc tttgattcaa tctatcgatt taaagaggac taactatgac tgaaatcatc
    19441 caaacagata ctattttaga ggctaagaac ttcattgtac tggaaaaata caccaagttg
    19501 gaaaagccta gcacctatca gacggaagca gacttggagc gagagctggt tagcgatttg
    19561 cggcagcagg gatacgagta cctcaacaat ctgacgaccc cagaagctct cttagataac
    19621 ctaaagaccc agatggaagc ccttaatggc gtggtttttt ctgaggcaga atggctgcgt
    19681 tttttagagg agtacctcaa taagcctagt gatggtttga ttgaccgcac ccgaaagctc
    19741 cacgataacc acatctacga ctttatcttt gacgatgggc atatccaaaa tatttatctc
    19801 tgggataaga aaaatatcag tcgaaataag cttcaggtca ttaaccaaat gtctcaagtt
    19861 gggacttcaa gtaaccgtta tgatgtgacc attttggtta atgggctacc cttagtacaa
    19921 attgagctta aaaagcgtgg ggtggctatt cgtgaggctt tcaaccaggt tcaccgttac
    19981 agtaaggaaa gctttaatga ggaaaattcg ctcttcaagt atctccagat ttttgtcatt
    20041 tcaaatggga cggatactcg ctattttgct aataccacta agcgagagaa aaattctttt
    20101 gactttacca tgaattgggc actaaaaaat aatgagccaa tcaaggattt gaaggatttt
    20161 acagcgacct tcttcagtca gcagacactc ttaaacattc tcatcaacta ctcagttttt
    20221 gatactagtg ataccctcct aatcatgcgt ccctatcaga ttgctgcgac ggagcgcatc
    20281 atctggaaga ttcgttcggc cattgatagc aaaatcaaga gtggtcctga gactggcggc
    20341 tatatctggc atacgacggg gtctggtaag accttgacca gttttaaggc tgcgagactg
    20401 gcgactgaga tggataaagt ggacaaggtt ttctttgtgg ttgataggaa agacttggac
    20461 taccagacta tgaaagaata ccagcgtttt tcacctgact cagttaatgg gtcaaatagc
    20521 acagctggac ttaaacgcaa tatcgaaaaa gatgacaata agattgttgt gacgacgatt
    20581 caaaagctca ataactttat gtctagtgaa gcacagcatg agatttacaa caagcaagtg
    20641 gtctttatct ttgacgaatg ccactgttca cagtttggcg aggctcaaaa gcgcttaaaa
    20701 caaaagttta agaagtattg tcagtttggt tttacaggca cgccgattaa agttgaaaat
    20761 gctttaggca gtgagacgac agcttctgta ttcggtcggg agcttcatgc atacgtcatt
    20821 actgatgcta tccgtgacca aaaggtgttg aaatttaagg tggattataa tgatgttcgt
    20881 ccacagttta agtcgttaga aactgagcaa gatttaggga aattatctgc tgctgaaaat
    20941 aaaaaagccc tacttcatcc aacacggatt acagagattt cggcttatat tttagaacat
    21001 tttaatcaaa agacacatag gcaaaacggt aaaggattta acgctatgtt tgctgtgtca
    21061 agtgtcgagg cggccaaggc ttactaccaa gagttgcaag accaacaagc tggaaaagct
    21121 aaaccattga agattgcaac catcttctct tatgcagcaa atgaggagca ggctgcgatt
    21181 ggggagattg atgacgagac tttcagccct gctgacttgt cagatattag tagtaaggaa
    21241 tttttgagcg gagcgatttc cgattataat cgcctttttc agactaattt tagtatcaat
    21301 ggcaatgagt ttcaaaacta ttaccgtgat ttagctaagc gagttaagtc tggagaagtg
    21361 gatttgctga ttgtcgttgg tatgtttttg actggttttg atgcaccaac cttgaatact
    21421 ctttttgtgg ataaaaactt gcgttatcat gggcttattc aggctttttc tcggacgaat
    21481 cggatttata atgcgacaaa gacatttgga aatattgtaa ctttccgtga tttggagaag
    21541 gctacgacgg atgctattaa gttgttcggg aagacggaga cggctgatat tctgttagag
    21601 cgctcttacg aggactacat gaatggctac attgaggctg gtcaagagca aaaaggatat
    21661 ttggaagtcg taaaagaatt gcaggagaga tttccagatc caacgactat tatcaaagaa
    21721 agtgataaga aagaatttgt gaccttgttt ggtcagttct tgcgcttgga taatatcttg
    21781 cagaactatg atgatttcat gagtttgcag gctttgcaag agttagatgt tacagatata
    21841 gaggctttgg cagatttcaa aggacgtttt catttggatg acgaagcagt tgcagtactc
    21901 tctcaactgg acatcccaag tgttcgtgag attcaagatt atcgctccgc ttacaatgat
    21961 atcaagtctt ggtatgacaa tgagcggcgt aatcagcaga ataacgattc cgaaatcgac
    22021 tgggatgcgg ttgtctttga agtggagttg ttgaaatcac aggaaatcaa tctggactat
    22081 attctggaat tgatttttga aaccaaccaa aaggtatctg acaaggatca actcattgaa
    22141 gaaattacac gaactatccg tgctagtctg ggtcagagag ctaaggaaag tttgatcgtg
    22201 gattttatca atgccagtga cttggacagt ttttctgaga agtcagatat cttggagcaa
    22261 ttttatacat ttgcccgtca aaaacaaaaa gaagcagtgg ctaatttgat tgagactgag
    22321 ggattgaatg tagagagtgc tagccgctat attcagatgt cactcaaacg agagtatgcc
    22381 agtgaaaatg gtaatgctct caatgaagca cttcctaaga tgagtccgct caatcctcaa
    22441 tatcgtacca aaaagcagat ggtgtttgaa aaaattgtgg atttggtgga gatatttaag
    22501 gggattggtg gagaaattta attattatta tttcttctag atatagaaga gataaacttt
    22561 aaattagagc ttgaaatttt aagaaatatt aaggcatcat atcagtagta taaaaagctg
    22621 acttataatt tatttggaaa cgacagttaa tcctaaaata cgatgcttga tatggaggag
    22681 gcttaaactt ggaaaataaa aaggatttaa ttcaaacctt agcctactac caattctcac
    22741 tagaaaacca atacttggat agaaaatcag cacgaaagaa gccgcaagaa ttactcaagc
    22801 atctgattgc ttttgccaat gcggacggcg gtcagttggt tattggtatt gaagatgaga
    22861 agcaggacaa tattatcact ggtttcaagg atggcagagc ttatcccata gacgatttca
    22921 aaaaaattga ccatgagatg cgggagactc ctctggattt gtctttagag gaaatccctg
    22981 tgctaaatca taagggagaa gatgacctga ttttggttat ttctgttgaa ttatcgtcga
    23041 accgagtgat tgctgcgcct aatgatgagg tttatctgcg tcagggcgat gaatcggtta
    23101 aattaagcta tgagcaacgt actcagctta gctatgataa gggccaacgt ttctttgaag
    23161 atgaagtggt acctgatgcg accttggaag atattgatga tgggttagtc caggacttca
    23221 aaaatcggtt tgatatttca gagcgctcca tggaagaagt tcttaaagca agacgattct
    23281 tggttaatgg taaattaact aaggcagcga ttctactctt tgccaaatat ccatcagcgt
    23341 tttttccaca agctcgtgtt cgttttcaac ggtttgacgg gacggatatg ggaacaggca
    23401 gtagctttaa tgttattaaa gaagtaactt ttgatgatgc tctgcccacc ttaattatca
    23461 aagtgcgaga ttttatccgt actcagctgc gtgaatttca gtacttagac gataatgggc
    23521 aattccagat tttgcctgag tatcctgaat ttgcttggtt tgagggtgtt gtcaatgcgg
    23581 tgactcaccg tgattactct gtctatgggg atcacattcg tgtactcatg tttgatgata
    23641 gactggagat tcatagccca gggaaattac caaatatcgt taccgttgac aatatcaagc
    23701 atgaatgttt ttctagaaat cctcggattg cgagaaccct gactgaattt ggatgggttc
    23761 gtgagatgaa tgaaggagtg aagcgtatct attctgagat ggaatcagct tttcttcatg
    23821 aacctaaata tttagaacca ggtaataagg tagttttgac ccttgaaaat aacatcgtga
    23881 gtcgacatct ccgaacacga gatagtttgg aaaaacaatt ttctgatttt ggaaatctga
    23941 ctgcagatga acaagctatc gttcactaca tgtataattc tggcgataaa atgacaacag
    24001 caaaggcgat tgagttgaca gggagaagtc gttcgtttgt tgtcaaaatg ctacatcatc
    24061 ttcgtgattt agaaatcatc acttggtttg gttcaagtaa aaatgaccgt aatcaatatt
    24121 atcttttagt tgataaatga ttgcagccag gatacttatt agtaataaga atacagtaga
    24181 atacagaaaa agtggtgttc cataaaatat tgatcaccac ttttgattat
//
LOCUS       DARYYD010000030        24206 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.030, whole genome shotgun sequence.
ACCESSION   DARYYD010000030 DARYYD010000000
VERSION     DARYYD010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24206
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.030"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(93..869)
                     /locus_tag="TV188_001174"
                     /pseudo
     CDS             complement(93..869)
                     /locus_tag="TV188_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
     gene            complement(965..2512)
                     /locus_tag="TV188_001175"
     CDS             complement(965..2512)
                     /locus_tag="TV188_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1534534.1"
                     /translation="MKTSLKKNNKFWTAALAVIVSISCILGLWTVVYAKEKSSDAPTK
                     NEAVQTEVEVNVKYIFEDEKVFKEEKIKAEKGQLLDSGDLPMLPDDMKFIDEFLFYEV
                     KGDGNDEIIRKVAKTEVKDKETQTEEEKPKQDESTQTEATKTEDKGTQTELSKDDISK
                     MEKEAKELQEKFDKLNGELKDKDKQKEKIKDLEDEIDSLKEKMKKDKGNKDLSEDMKK
                     EIDKLTDKVKELEKKATETKKSSEAINSVTPISPISGIKTSSSISPQTPQTSVSSSGK
                     GSSDTVSSGNATKDTSKTEVKEKEKEVRYSNKLTAKAPANNSSQDSSMEGASSNVNTN
                     KGVASSPSKARGTVTENKDNGNKDYPIHHGDSSDNKETDQYSADARQFITFQTKNGKT
                     FHLIINHDEDSENVMLLTEVSEDDLLNMVEKKEAPKQEIVKEEPVKEEVKPEKKEEKS
                     NLGTYIILLLVVGGALGAGYYFKVVKKKEDKELEALEEEDDDFFSEAESEEETNDVDE
                     VEAEDEQ"
     gene            complement(2487..2726)
                     /locus_tag="TV188_001176"
     CDS             complement(2487..2726)
                     /locus_tag="TV188_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1534535.1"
                     /translation="MKKELTAVKNRIKKLKDKKALIDEELEPLFIREEELENEEIIMI
                     CRKNNITISDLMTKVNREKAELKKERTNENQFEKE"
     gene            complement(2739..4862)
                     /locus_tag="TV188_001177"
     CDS             complement(2739..4862)
                     /locus_tag="TV188_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1534536.1"
                     /translation="MDGKLKKDFRERHKASLEREMLKAETSSIPEESKLKHNDDYRGK
                     IVHDKDRFQDKVHEKISKVRSENEQIEGTSKRNAKYRASDKGSVNEAGKADYDTEVKN
                     GKIYDSLGQDLDNDGIIDRYDNDFRDSDYFESTYDVEDNLPQKEKSLENPSKNHKAQK
                     NKYKRKNYSESLYTRKKDDVPKENKPEDKKAGKDVAGEKEHSSLSKDQKKKLKKDMVK
                     VSALSGLAKGSETVRDYLSHGSDENKGVEAGEKTADASSKLIHGIKRYSDKKRAKKGY
                     ELTNKDYKIRKRKSKLEFRDAKEELKKTDEYKRASAYKRFQKKNQVKAAISRENKSRL
                     RDRIKEGLIGTLKSSKDMIIRKAKGLMLIFVGIIILGNFVINFAGTGMTGFMNSTNSV
                     LTTSYLSKPNVLSEINQKFSAMESELQSEVDHVEENYPGYDEYILNNTEYIGHNVHEL
                     LSYITSRCGEVKSVSEVETILKELFESMYDLEYREEIEIRYRTVTETYTDEDGNEYTE
                     SHEEPYEYKKLIVTLHKKEMDSIIRRVFKDYPDNLKHYEALFLAQGNMGEAFRNSDLI
                     SANGGVGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGYIGGNAN
                     DMYRNYTFTSDRSKLKVGMLVAVESSSSGSTAGLTYGHVGIYIGDGKVIDNIGYIRVT
                     TLDDWIATFCKHHPVGFGFPPNVNR"
     gene            complement(4866..7295)
                     /locus_tag="TV188_001178"
     CDS             complement(4866..7295)
                     /locus_tag="TV188_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1534537.1"
                     /translation="MNKKRKIQQLKLEENKKALKKERKDLKQSKGKSNKEKSGLLDLI
                     FRKEQKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALDEDRDLIFNQF
                     ANFLNSFDPSIAIEFSYINQLGRNEEMKSAIQIPDKGDGFDDIRLEFREMLKSQIVKG
                     NNGLKKSKYVTFTVEADNLEQATSKLERLDIDILSNLKSMGVRAESLTVEERLKILHD
                     ILNPNKTFEFSYKDLKKKESTKTYIVPDEFNFMPSRYFKFGKFIGATSHFQILASELS
                     DRMLSEFLDIDDNINISFHIKAIDQSEAIKMVKRKNTDIDKMRIEENKKAVRSGYDMD
                     ILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKH
                     NCKLKRLDHTQEQGLVSVLPLGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYY
                     GLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMANAILVTDDDVIICDPEG
                     EYGNLVRQFNGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGS
                     GLTAEEKSVIDRCLPKIYERYFENPTYDNMPILQDLYDMLKGQEEKVGKKLATEMEIY
                     VSGSLNVFNHRSNVDLNKKLLCFDIKELGSQLKKIGMLVIQDQVWNKVSQNRGNKATR
                     YYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIENIFDNTDF
                     VLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILY
                     QKMTTKPEEVR"
     gene            complement(7207..7596)
                     /locus_tag="TV188_001179"
     CDS             complement(7207..7596)
                     /locus_tag="TV188_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1534538.1"
                     /translation="MAYVPIPKDLKKVKTKVAFNLTKRQLIGFTIAGLVGIPVYLFMR
                     KVVPNDIAFIFLIVSTLPIFFITLFEKDGLTFEKYFKHIYLHKFYQPAKRVRKEVYLE
                     QEKKNSATKVRRKQKGIKKGEKGLKAK"
     gene            complement(7600..7863)
                     /locus_tag="TV188_001180"
     CDS             complement(7600..7863)
                     /locus_tag="TV188_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1534539.1"
                     /translation="MNKRKTVFTAVVMVAGIMAVIDRIRLHNKAAELEERTQDIGRCH
                     NDFCLMQQRYNKNTDEQLAIIQDEIGSVYEHFEEFSKGKEDGR"
     gene            complement(7883..8749)
                     /locus_tag="TV188_001181"
                     /pseudo
     CDS             complement(7883..8749)
                     /locus_tag="TV188_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8769..8984)
                     /locus_tag="TV188_001182"
     CDS             complement(8769..8984)
                     /locus_tag="TV188_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1534540.1"
                     /translation="MEFFAQAVNVLKILVMAVGAGLGAWGVINLMEGYGNDNPGAKSQ
                     GIKQLMAGGGIVLIGLKLIPLLANVLR"
     gene            complement(8988..9299)
                     /locus_tag="TV188_001183"
     CDS             complement(8988..9299)
                     /locus_tag="TV188_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1534541.1"
                     /translation="MKQEMININANLVAEPTFSSFEKEGKEVEVVNFTLVKKYGKGKE
                     YINCAAYGEKADKAKDFEKGDLIHVFGYFKKREKEGKTYKNFVVKSYNKIEKKEENEE
                     E"
     gene            complement(9463..11244)
                     /locus_tag="TV188_001184"
                     /pseudo
     CDS             complement(9463..11244)
                     /locus_tag="TV188_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565754.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            complement(11241..11726)
                     /locus_tag="TV188_001185"
     CDS             complement(11241..11726)
                     /locus_tag="TV188_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009346332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HEL1534542.1"
                     /translation="MINEEIARKTLNMEVRAAKVTGKLILNLLKKLMKEAEKLGGLEK
                     LVNANGNEVKLKDMVKKGQLEEIPVEEAELKELKKELNRYGVKFSVMKDKETGKYSVF
                     FQAKDMKVMDKAFKHALAQSEKKTERKESIHKNIEKFKEMAKNSVSKDKIKNKQKEQS
                     L"
     gene            complement(11723..12497)
                     /locus_tag="TV188_001186"
                     /pseudo
     CDS             complement(11723..12497)
                     /locus_tag="TV188_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588832.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
     gene            complement(12494..13273)
                     /locus_tag="TV188_001187"
     CDS             complement(12494..13273)
                     /locus_tag="TV188_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HEL1534543.1"
                     /translation="MDFDYFYNREAERFNFLKVPEILVDGEEFKGLSAEAIILYSMLL
                     KRTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDSKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKEDDLQKLKNFTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYNFSENGLGTFQNVFLAAEDISDLQIIMNSQLDNYIERLSAYIKSTG
                     KTYKDHKATILSWFYKDQGRGKEVKTSNIPTWEEYDKGEHL"
     gene            complement(13360..13641)
                     /locus_tag="TV188_001188"
     CDS             complement(13360..13641)
                     /locus_tag="TV188_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534544.1"
                     /translation="MRWIIKIILFPFSLLLSVLTAFLTFILGIGTTILYFLMLMCIVA
                     AIGSFMQKDISLGIEALVLGFLLSPYGIPMVGAAVIAFFKGINEAIKSI"
     gene            complement(13661..15292)
                     /gene="rlmD"
                     /locus_tag="TV188_001189"
     CDS             complement(13661..15292)
                     /gene="rlmD"
                     /locus_tag="TV188_001189"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000902659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1534545.1"
                     /translation="MLSKNDIVQVEISDLSHDGLGIAKHEGFVFFVENALPGEIIQMR
                     VLKVNKNSGFGKVETYLTTSPMRQKKLDVTYLRTGIADLGHLLYPQQLLFKQKQVQDS
                     LYKIAGISNVEVKETIGMEYPYAYRNKAQVPVRRVNGQLETGFFRKHSHELVPISDFY
                     IQDKEIDRLIAFTRDLLRRFDIKPYDEKEQSGLIRHLVVRRGHYSGEIMLVLVTTRPK
                     IFRINQMIDSLVAEFPAITSILQNINDKPTNVIFGKAFTRLYGKETITDTILGNQYCI
                     SAQSFYQVNTTMAEKLYQTAIDFSELTADDVVIDAYSGIGTIGLSFAKEVKAVYGVEV
                     IEAAVRDAEKNAALNGITNAYYVADSAENAMANWCQEGIKPTVIIVDPPRKGLTESFI
                     KASAAMQPDKITYISCNPATMARDIKRYEELGYKLQKVQPVDLFPMTHHVETVALLSK
                     LNVDKYISVEIELDELDLTSAESKATYAKIKEYILEKFGFKVSTLYIAQIKRKCGIEL
                     RENYNKSKKDKQVIPQCTPEKEKAIMDALRHFKMI"
     gene            complement(15370..16800)
                     /locus_tag="TV188_001190"
     CDS             complement(15370..16800)
                     /locus_tag="TV188_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1534546.1"
                     /translation="MTRYQKGGLSHHEELRYFYLLRNLNYLTETERREFTFLKSKMES
                     RAMPSRSQRSLTHYTRGGRDDYAQASQDNADAYDMSDEQQAGPNGLPLYPRSERRSKR
                     HQQKPILAPQQDFYDDPDQAIYEELAPEAMPKKGRRKKKKGRLRRFFRILFFLLLLLV
                     AGIAFMFFKGMMDVSTNKANYKPAVSQVFHGQDTSDGTNILILGSDQRITQGSTDART
                     DTIMVVNVGNKENKIKMVSFMRDTLVNIPGYSYNNQDSYDLKLNASFNLGEQENHQGA
                     EFVRQTLKHNFDIDIKYYVMVDFETFAEAIDTLFPDGVTIDAKFATVNGEAVAAVDVP
                     DDLRMKDGVVPNQTITVGEQKMDGRTLLNYARFRKDDEGDFGRTVRQQQVMAAIMSQI
                     KDPTKLFTGSAAIGKIYALTSTNVSFPFVLKNGVSVLTNGKNGVEHVTIPENGDWIDE
                     YDMYGGQALFIDFAKYQNRLSKLGLR"
     gene            complement(16999..17493)
                     /locus_tag="TV188_001191"
     CDS             complement(16999..17493)
                     /locus_tag="TV188_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1534547.1"
                     /translation="MTKLLLGFMGVGKTTVAAQLDEHFLDMDRLIEAKIGMSISAFFS
                     YRGEAAFRKLESDTLQEVLALDNETIVSTGGGVVLSKANRELIRKNHKNNILLTASFE
                     ALYDRLKKDRLCQRPLFLNHSEAELYAIFQQRMALYEGLADKVINVEHRTPKEVAAII
                     ANMS"
     gene            complement(17486..18769)
                     /gene="aroA"
                     /locus_tag="TV188_001192"
     CDS             complement(17486..18769)
                     /gene="aroA"
                     /locus_tag="TV188_001192"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEL1534548.1"
                     /translation="MKLKTKAKALRGRLRVPGDKSISHRAVIFGAIAEGQTVIHGLLR
                     GQDVLATIQAFRDLGVTIYESADSLIIEGRGFKGLKPAQKPLDMGNSGTSMRLLAGLL
                     AAQDFSVQLLGDDSLSRRPMDRITIPLSLMGAELSGQGEKELPPLIVKGCQELRPIHY
                     QLPVASAQVKSAILLAALQTQGETVILEKELTRNHTEEMIEQFGGKLSVAGKQISIKG
                     PQRLQGQTLQIPGDLSSAAFWLAAGLIVPGSDLVLENVGINPTRTGLLEVIEKMGGRI
                     SYQAVDKDRQAATLKVSYSTLKGIEISGDLIPRLIDELPVIALLATQAQGTTYIRDAQ
                     ELRVKETDRIQAVTDVLGQMGADIQATEDGMVTRGKTPLHGAAVSTCGDHRIGMMTAI
                     AALLVEEGQVTLERAEAILTSYPDFFKDLERLWHD"
     gene            complement(18902..19840)
                     /locus_tag="TV188_001193"
     CDS             complement(18902..19840)
                     /locus_tag="TV188_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEL1534549.1"
                     /translation="MSIKKFLDKVISKWQYEPIQAFMRHFQSAEMDLSAIAVAYYLIL
                     TAFPLIVIAANIFPYLNIDISDLLRLMKEQLPKDIYRSASSIVVNIFSKPSGSVLGVA
                     TLTGLWTMSRSLTSLQKAFNKAYDASEHRDFLLGHLVGLLTSLLILFLLTFALIFSTF
                     SKAAIQVLDRHYHLNDNITTLFLFLIQPITILIIFVGLMLLYFLLPNIKIKKIRYILP
                     GTFFTTFVMIFLSNMVGNYVVHNVERMVDIKTFGSVMIFIIMLWFIFLARILIMGAVF
                     NATYQELSIGKLEGRSGNVVSLIKKTLGNDGAPPKK"
     gene            complement(19842..20702)
                     /locus_tag="TV188_001194"
     CDS             complement(19842..20702)
                     /locus_tag="TV188_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEL1534550.1"
                     /translation="MITLKSAREIEAMDRAGDFLAGIHIGLRQIIKPGVDMWEVEEYV
                     RRRCKEDNVLPLQIGVDGQLMDYPYATCCGLNDEVAHAFPRHYILQEGDLLKVDMVLS
                     EPLDKAVVDVAALDFDNVAEMKKWTESYTGGLADSCWAYAVGTPSDEVKRLMDVTKEA
                     MYRGIEQAVVGNRIGDIGAAVQQYAESHGYGVVRDLVGHGVGPTMHEEPMVPNYGTAG
                     RGLRLKEGMVLTVEPMINTGTWEINTDMKTGWAHKTLDGGLSCQYEHQFVITKDGPVI
                     LTSQGEERTY"
     gene            complement(20719..22002)
                     /locus_tag="TV188_001195"
     CDS             complement(20719..22002)
                     /locus_tag="TV188_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEL1534551.1"
                     /translation="MSKHQDILDYLERLAIGKRVSVRSISNHLKVSDGTAYRAIKEAE
                     NRGIVETKPRSGTVRIEKKGRVRIDRLTYAEIARISDSEVLAGHAGLGHEFSKFSIGA
                     MTQQNIHRYLIKGGLLIVGDRENIQLLALKNHNAILVTGGFPVSKQVIETADSQGIPV
                     MVTHYDTFTVATMINHALSNIRIKTDLKTVAQVLIPVEEYGCLYETDTVEEFNALIKK
                     TGQVRFPIVDALDQVVGVVSMRDVVDQPAETRLEQVMSPNPITAKPNASLANISQKMI
                     FEDLNMLPVVDDHHFLLGIITRRQAMENLPNHQPGNLYTYSQQMLSSLEETLDYYQVM
                     IEPTMIDSAGNLSNGVVAEFLKEISVRVLTKKHQKNIIIEQMMIYFLHAVQIDDQLRI
                     YPKIITENRRSSTLDMEVMVDDQVIAKAIITTKLN"
     gene            complement(21995..22549)
                     /locus_tag="TV188_001196"
     CDS             complement(21995..22549)
                     /locus_tag="TV188_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1534552.1"
                     /translation="MDIWTQLARFAFVETQRLLLRPFQYADHQPFYDMISHNSHYQFV
                     FPESMTKAESDFLMVNAFMKEPLGVWLIEDKTSHSMLGSIRLEKYDKQQASAEIGYFL
                     AQPFWGQGLMTEVLKTLTFLAFQEFGLRQLIIVTHLENKASQRVAEKAGFRLTKQFKG
                     SDRHSHHIRDYLEYQLTIGEYHYE"
     gene            complement(22843..24132)
                     /locus_tag="TV188_001197"
     CDS             complement(22843..24132)
                     /locus_tag="TV188_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622582.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEL1534553.1"
                     /translation="MEKNKKVSYFLRQSAVGLASVSAAFLVGTTSVGALDAATVLEPT
                     TAFIREAVREINQLSDDYADNQELQAVLANAGVEALAADTVDQAKAALDKAKAAVAGV
                     QLDEARREAYRTINALSDQHKSDQKVQLALVAAAAKVADAASVDQVNAAINDAHTAIA
                     DITGAALLEAKEAAINELKQYGISDYYVTLINKAKTVEGVNALKAEILSALPSSEVID
                     AAELTPALTSYKLVIKGATFSGETATKAVDAAVAEQTFRDYANKNGVDGVWAYDAATK
                     TFTVTEQPVAETIEAAELTPALTTYRLVIKGVTFSGETATKAVDAATAEQTFRQYAND
                     NGVTGEWAYDAATKTFTVTEALEESPADPEKPSASLPLTPLTPATKTAPAKQKDKQKA
                     KTLPTTGEKANPFFTAAALAIMASAGALAVTSKRQQD"
BASE COUNT         6492 a         5531 c         3926 g         8257 t
ORIGIN      
        1 gcattaaagc aaagctaaaa ggacttagcc ctgtgcaata cagaactaaa tcctttcaat
       61 aattattcgt ccaacttttt gggggcagta catttagtaa tcttttcttt ttgaatgaca
      121 tcagttattt caatcttatt gcccactaaa gttaagagct gctctgctgc tatttcatca
      181 tcaattctat ctgttgaaag tgtaaagcta tttgtagaaa gctctaccgt ataatatttt
      241 tctttcttaa agtttgctat ctcatcatct ctttttacga tcatagcaag agtcggtgtt
      301 tgtactctgc caacactgta attttgctta tacagacaag aatagagcct gctgatattc
      361 attccgacaa gccagtcagc gatagctctt gcctgtgccg actcaaagag attatcgtaa
      421 tcttttccgt cttttagatg atcaaagcca tctttaatgg cagtatcttc catagatgaa
      481 atccaaaggt gtttcatctt ctttttacaa ttcacttgat tatatacaag tctaaaaatg
      541 ctctcccctt ctctacctgc atcgcacgca ttgataaccg tatcaatttc tttgtcgttc
      601 atcaactttt taaggatgtt aaattgtttc ttggttgact ttgccacttc atacttatag
      661 tccttgggga taatcggtaa atcaaccata ttccacttgg catacttttc atcataaaca
      721 tccggatttg ccatttgaat taagtgtcca acacaccaag atactttgta tccatttccc
      781 tcataatatc cgtctttctt tttatttgct ccaagtactt ttgcaatact taatgctaca
      841 cttggttttt ctgcaatgac taacttcatt tctgtactgc ctcctgtttt caatataaaa
      901 gggcgaaaga ttttattctc ccgccctgca tttgcaccaa atactgtatt tttttggtgc
      961 agcattactg ctcatcttcc gcttctactt catctacatc atttgtttct tcctcgcttt
     1021 cagcttcaga aaagaaatca tcatcttctt cctctaatgc ttcaagctcc ttatcttctt
     1081 tcttttttac aaccttaaag tagtatcctg ctcccaatgc tccgcctaca acaagaagca
     1141 gaataatata tgttcctaaa ttactctttt cttctttttt ctcaggcttt acttcttcct
     1201 taacaggttc ttcttttaca atctcctgct ttggagcttc ttttttctct accatgttaa
     1261 gcaaatcatc ttcggatact tctgtaagaa gcatgacatt ctcactatcc tcatcgtggt
     1321 tgatgatgag atgaaaggtc ttaccgtttt tagtttgaaa ggtaataaac tgtcttgcat
     1381 cagcggaata ttgatccgtt tctttattat cgctgctatc cccatgatga atcggataat
     1441 ctttatttcc attatcttta ttttctgtaa cagttcctct tgcctttgac ggagatgaag
     1501 ctactccctt attggtattt acattactac ttgccccctc cattgacgaa tcttgactgc
     1561 tgttattagc aggtgctttt gctgtcaatt tattagaata gcgaacttcc ttttctttct
     1621 cctttacttc tgttttgctt gtatcctttg tagcattccc tgaactcacc gtatcagatg
     1681 agcctttacc ggaactactt acagaagtct gtggtgtttg gggagaaatg cttgagcttg
     1741 tcttaattcc ggaaatagga ctaatcggtg taacagaatt tattgcttca gaagatttct
     1801 ttgtttcagt tgcctttttc tcaagctctt tcaccttatc agtcagctta tctatttcct
     1861 ttttcatatc ttctgataag tccttatttc ctttatcttt cttcattttc tctttcaggc
     1921 tgtcaatttc atcttcaagg tctttgattt tttctttctg cttatccttg tctttaagct
     1981 caccatttaa cttatcaaat ttttcttgaa gctctttagc ctctttttcc atcttagaaa
     2041 tatcgtcttt agaaagctct gtctgtgtgc ctttatcctc cgtttttgta gcttctgttt
     2101 gcgtgctttc gtcctgcttt ggtttttctt cttccgtttg cgtttcctta tccttaacct
     2161 cagtctttgc taccttacgg ataatttcat catttccatc tccctttact tcataaaaca
     2221 ggaattcatc aataaatttc atatcatcag ggagcattgg aagatcgcca ctatcaagaa
     2281 gctgtccttt ctctgcctta atcttttctt ccttaaatac cttttcatct tcaaagatat
     2341 actttacatt tacttcaact tccgtttgga cagcttcgtt ttttgtagga gcgtcagagc
     2401 ttttctcctt ggcgtaaaca accgtccaaa gtcctaaaat gcagctaata cttacaatta
     2461 ctgcaagtgc tgctgtccaa aacttattat tctttttcaa actggttttc atttgtcctc
     2521 tcctttttca gttctgcttt ttctctgttt acctttgtca ttaaatcaga aattgtgatg
     2581 ttgttctttc tgcaaatcat gatgatttct tcattttcaa gttcttcttc acgaataaat
     2641 aaaggctcca attcttcatc aatcagagcc tttttatcct ttaacttttt tattctgttt
     2701 tttactgctg tcagttcttt tttcatattg ttccctcctt atctgtttac atttggtgga
     2761 aaaccaaagc ctaccggatg gtgtttacaa aaagtcgcaa tccaatcatc taaagtagtt
     2821 actcttatat aaccgatatt atcaataacc ttgccgtctc cgatatagat tccgacatga
     2881 ccataggtaa gtcctgctgt gcttccgcta ctgctgcttt ctaccgctac aagcattcct
     2941 accttgagct ttgacctatc ggatgtaaag gtatagtttc gatacatatc attagcattt
     3001 cctccgatat atccaagtcc cgcattttgg taaacttgcg atacccacat ggcacaccag
     3061 cctgcacccg gagatggagt gatatatgca gcattaacaa tcttcttttg tacttccgaa
     3121 gatgcctcat actctttccc accacctaca ccgccattag cactgataag gtcagaattt
     3181 ctaaaggctt ctcccatatt tccttgagca aggaataagg cttcatagtg ctttaaatta
     3241 tcgggatagt ctttaaagac ccttcggata atgctgtcca tctctttttt atgaagcgtt
     3301 acaatgagct tcttatattc ataaggctct tcatggcttt cggtatattc attgccatct
     3361 tcatcggtat aggtttctgt aactgtcctg tatctgattt caatttcttc cctgtattca
     3421 aggtcataca tggactcaaa caattctttt aatatggttt ctacttccga tacactcttt
     3481 acctctccgc accttgatgt aatgtaggat aaaagctcat ggacattatg accgatatac
     3541 tctgtgttgt ttaagatata ctcatcatat ccgggataat tctcttctac atgatccact
     3601 tcactttgaa gctcactctc catagcagaa aacttctgat tgatttcact tagaacattt
     3661 ggctttgata aatagcttgt tgtaagaaca gagtttgtag agttcataaa gcctgtcatg
     3721 cctgttcctg caaagttaat cacaaaattt cctaagatga tgatacctac gaagataagc
     3781 attagtcctt tggcttttcg gataatcata tcctttgagc ttttcagtgt tccgataagt
     3841 ccctctttaa tccgatctct gagtcttgac ttattctcac gagaaatcgc tgcctttacc
     3901 tgatttttct tttgaaatct tttataggca cttgctcttt tatactcatc tgtctttttc
     3961 agttcctctt tggcatcacg aaactctaac ttggatttac gctttctgat tttatagtcc
     4021 ttatttgtaa gctcatatcc ttttttagct cttttcttat ctgagtatct ctttatacca
     4081 tgaatgagtt ttgaacttgc atcggctgtt ttttctcccg cttctacgcc tttattttca
     4141 tcacttccat gagaaaggta atctcttacg gtttcacttc ctttggcaag tcctgacagg
     4201 gcagatactt ttaccatatc tttcttcagc tttttctttt ggtcttttga aagactgcta
     4261 tgttcttttt cgcccgcaac atctttccct gcctttttat cttcaggctt attctctttt
     4321 ggtacatcgt ccttttttct tgtatagagg ctttcggaat agtttttcct tttatactta
     4381 ttcttttgag ccttatgatt tttagaggga ttttctaatg atttttcttt ttgaggtaga
     4441 ttatcctcta catcataggt tgattcaaag tagtcgctgt ccctaaaatc attatcgtat
     4501 ctgtctatga ttccatcatt atcaaggtct tgtcctaaag aatcatagat tttcccgttc
     4561 tttacctcag tatcatagtc agcctttcct gcttcattta cacttccctt atcagaagcc
     4621 ctatactttg catttctttt agaagtcccc tctatctgct cattttcaga tcttaccttg
     4681 cttatcttct catgaacctt gtcctgaaat ctatctttgt catggacaat ttttcctctg
     4741 taatcatcgt tatgctttag cttactttct tcaggtatag agcttgtttc agctttaagc
     4801 atctcccttt caaggcttgc cttatgcctt tctctaaaat cttttttcag cttcccatcc
     4861 ataagctacc tcacttcttc aggcttggta gtcatcttct gataaagaat tgtatctttc
     4921 ggaaacttat caaggaaagg cacaatggta tttccaaaga aaagtagtcc ctcgccctca
     4981 ttggagttcg taacatatct aagctgcgga agtgagattt taagtttcct tgcaagtatt
     5041 tccctatctc ccgaagcctg atttaacatt aagacaaagt ccgtattatc aaagatattt
     5101 tcaatttcct tactcataag taggtctttg acattttgcg tgataccagt cgggattcct
     5161 ccccattttc taaaacgctt ccaaatctct accgaatatg aagctgtctg ctcatctttt
     5221 aacagcaagt gaaactcatc tatatagtac cttgtagcct tgtttcctct gttttgcgat
     5281 accttattcc acacctgatc ctgtataaca agcataccta ttttctttaa ttgacttcca
     5341 agctccttaa tatcaaaaca aagtagcttc ttatttaagt ccacatttga cctgtgatta
     5401 aagacattaa gagaacctga aacataaatt tccatctctg ttgccagctt tttccctacc
     5461 ttttcttcct gcccttttaa catatcgtat aggtcttgaa gtataggcat attgtcataa
     5521 gtcggatttt caaagtacct ttcgtaaatc ttaggtaagc atctatctat aacggacttt
     5581 tcttccgctg taagtccact accaccaact acaagctcaa gcatagacat aatgaagttt
     5641 gccttgtctt taagaggtgc gtccccatca ccgtagttca tatttatatc aagtggattc
     5701 aggtaatctt ttgacttact gctgacctta atgacttctc cattaaactg tcttacaagg
     5761 tttccatact ctccctccgg atcacagata atcacatcat cgtccgttac taaaatcgca
     5821 tttgccatct ctcttttggc actaaaggac ttaccactac ccggagttcc taagattaga
     5881 ccgtttgggt tctttaattt ctttcgatcc gccataatca ggttatggct taaagcgttt
     5941 agtccatagt ataggctatt acttgaattg ataaaaagct cctctgttgt aaaaggcata
     6001 aagactgctg ttgatgatga ggttagccct ctatctattt caatcttgtt taccccaaga
     6061 ggcagcacgc tcactaagcc ttgttcctgc gtatggtcaa gtcttttcaa tttacagtta
     6121 tgcttgtttg caatggagct tatctgagct atggtgttat cgagcttttg cactgtcctt
     6181 gcaaaattca taaagacaat acttacaaca aacatacgct catctcttgt ctgtaaatct
     6241 tttaaaagac tttttacatc ttctccgtaa gtaattaaat cacttggaag aatgtccatg
     6301 tcatagcctg accttacagc tttcttgttt tcctcaattc gcatcttatc aatatcggtg
     6361 ttttttcgtt ttaccatctt gatggcttct gactggtcaa tcgccttaat atgaaaagat
     6421 atattgatgt tatcatcaat atccaaaaac tccgataaca tacggtctga aagctcactt
     6481 gcaaggattt gaaaatgact tgttgctccg ataaacttcc caaacttgaa atacctgctt
     6541 ggcataaagt taaattcatc aggcacgata tatgttttgg tactttcctt tttcttcagg
     6601 tctttgtagg aaaactcaaa ggtcttattc ggatttaata tatcgtgaag aatctttagc
     6661 ctttcctcta ctgtaagact ttcagctctt acccccatgc ttttgagatt agataatata
     6721 tctatatcca atctttcaag ttttgatgta gcctgttcta aattgtctgc ctctactgta
     6781 aaggttacat actttgattt tttcagtccg ttatttcctt ttacaatctg actttttagc
     6841 atctctctaa actcaagtcg tatatcgtca aatccgtccc ctttatccgg tatctgaatt
     6901 gccgatttca tttcttcgtt tcgtccaagc tgattgatgt aggaaaactc aatcgctatg
     6961 cttggatcaa aggaatttag aaagtttgca aactgattaa aaatcaaatc cctatcttca
     7021 tctaaagcaa gctgatagtt aatgtcctga aaggctatgc ttttactgaa gtgcttttca
     7081 tcgagctggc atatcccgct ttttaagagt ctaagatagg gaatggtatc ttctaccgta
     7141 tagcgttttt gctcttttct aaagataaga tcaagtagtc cgctcttttc tttgttagac
     7201 tttcccttac tttgctttaa gtcctttctc tcctttttta atgccttttt gttttcttct
     7261 aactttagtt gctgaatttt tcttttcttg ttcaaggtaa acctcctttc tcactctctt
     7321 tgccggctga taaaacttat gaaggtagat atgcttaaaa tatttctcaa aggtcagtcc
     7381 gtccttttca aaaagtgtga taaaaaagat tggaagtgtg gacacgataa ggaatatgaa
     7441 agctatatcg tttggtacta cctttctcat aaataaatag acaggtattc caacaagtcc
     7501 tgcaatggta aatcctatga gctgtctttt tgtaaggtta aaggctacct ttgtcttgac
     7561 cttctttaag tccttgggta ttggtacata cgccatagct tacctcccat cttctttacc
     7621 ctttgaaaac tcctcaaagt gttcatatac agagccgatt tcatcctgaa taattgcaag
     7681 ctgttcatct gtattcttgt tatatctttg ctgcattaag caaaaatcat tatggcagcg
     7741 accgatgtcc tgtgttcttt cttctaattc ggcagctttg ttatgaagcc tgattctatc
     7801 aattaccgcc ataatgcctg cgaccattac tactgctgta aatactgttt ttcttttatt
     7861 catactatct ttcctttctt ttttagtgtg catttaatac gcttttggcc agtgttccgc
     7921 tctttagcat cattaacccc agcaaaaccg cataaccaag tatcgtcatg gtacttgtgt
     7981 gtatatctgt tatttcaatc gtcttaacta atactgcgta aattccaaga caaaccatta
     8041 aaaagagtcc ttgtagtcca agtgcaaata atcctttgat gtaatttgtg ccaatttgcc
     8101 cccattcttt gtttcccatc gtggcaaatg gaatggctga aaccgatgaa taaacataaa
     8161 tctcaaacat ccttccgtaa accacaagca taatcactat ggaaattgcc tgtatggcaa
     8221 ctttaatgag cgaggtttca aagagaatca tgataagctc tccaagtccc ttttctttta
     8281 gggtatccat catcgccact atctgatctc cggaaacggt ggcagaggtg tttatcaccc
     8341 ctgccgcctt atttaccata tgctgtgcta catcaaagac cgccattgaa aattcaaaag
     8401 cgtgagatac caaccataca gcaattcaca tcttgatgat gtacttgaaa aattcaaatg
     8461 tatccgtatt atcatgtagg ttatttttct gtataaccat attgataagc tcgatacaaa
     8521 ggactgctgt gataattagt cccgctatgg gaataatgac cgaatcgtta atgcttttaa
     8581 taaaggtaaa tacatctcca ttccacccca taggagtttt tcctacatct gttgcaactg
     8641 caccaacctt gtcgttgatg tcaagaaaca tggactctaa gtttgcttgg ataccgccca
     8701 gtagaagctc cttaaagaat tcttctattt tgtcgaatat cccaaacatc taagctctcc
     8761 ttttcttctt atctgagtac atttgcaaga agtggaatca gcttaagtcc gataaggaca
     8821 atacctcctc ccgccatcaa ttgcttgatc ccttgacttt tggctcccgg attatcgtta
     8881 ccataacctt ccatcaggtt aatgacaccc catgctccaa gtcctgctcc tactgccata
     8941 accaaaatct ttaatacatt tactgcctgt gcgaaaaatt ccataattta ttcctcctca
     9001 ttttcttctt tcttttcaat cttgttgtat gacttcacta caaaattttt gtaagtcttt
     9061 ccctcttttt cacgcttctt aaagtagccg aatacatgaa tcaaatcgcc cttttcaaag
     9121 tcctttgctt tatccgcttt ttctccatag gctgcacaat tgatgtactc cttgccttta
     9181 ccgtacttct ttacaagcgt aaaatttaca acttctactt ctttaccctc tttttcaaaa
     9241 cttgagaaag taggttctgc cactaagttg gcgttgatgt taatcatttc ttgcttcatt
     9301 aaaaatttct ccttttcatt tcaataaaaa aagcgaccgg aagtattact tttccaatcg
     9361 ctatactcat actatttagt tttttactca gtgggacttc tgatccttat catcttgcct
     9421 ccttactttt gcataaaaaa gcagcaaatc tattttgtag acttactgca ttcttgtaat
     9481 aactgtttcc ctattcagtt ttgcttttcc tttccgtttc atgtagcttt ctatatcaaa
     9541 taaatttttc ttatcatagt cctcaagcag cttatagttc ttgtgctttg taatatcgta
     9601 cttatctgaa agaaaaggtc tgacacctct aagctgaaag atacattttc caccatccat
     9661 gaccgtaatc tcatcctgac tcatcagctc tttgcctgtt ttttgatagt taagtccaaa
     9721 gctcttttga tttgaccttg tttccgatgt gttgtaaagg tcgatagttt ctttaccaag
     9781 cgtttcggac agctctttta gtgttttttt cctttccacc taagaataag gtactatcac
     9841 agttacccac aatggtatca gcattatcct tatatattgc ctttagctga gattgtgcct
     9901 gtaagataat actcgctgaa atttctctac ttctaattgt ggctatgagc ttctcaaact
     9961 ttggaattaa gccgatattt gcaaactcat caagtaagca tcttacatga acaggaagtc
    10021 tgccaccata tacatcatcc gccttatcgc aaagtagatt aaataactgt gaatacataa
    10081 tagacactac aaagttaaag gtatcatctg tatcagagat aataacaaag agtgctgtct
    10141 ttctatctcc caatgtatca agctcaagtt cgtcttcact catcaaatct ctaagttcct
    10201 gaatatcaaa tggagcaagc cttgcaccac aagatataag aatagatttt gctgtctttc
    10261 ccgcagccaa tttatatttt ttatattgct tgaccgcaaa gtgcgtaggc tcctttttct
    10321 caagtgcttc aaagagtctg tctattggat tcatataggt ttcatcatct tctcttactt
    10381 ctgaagcgtc tatcatatca aggagcgttg caaagttctt ttcttctctt ggagcttcat
    10441 agaagatata tccgataagt gctgtgtagt agagtttttc cgctttgacc caaaaatctt
    10501 cacccgcttt ttctccctca ccttttgtat ttgcaatgat tgtctgcact aatttgagta
    10561 tatctttctc agaatggata taggcaaagg gattgtattt catgctcttt ttgaagttta
    10621 tggtatttag aatttttatc tcatatccat tgtcttcaag catcttgcca cattcaatga
    10681 ctatcgttcc tttcggatcg gttacgcaat agctactgtg catctgcata aggttcggtt
    10741 ttacataaaa tcttgtctta ccacttcctg atccaccgat tacaagtaca ttcttgttac
    10801 gagcatactt tggattagcc ggtctaccat tcatagttag gcgttctgtc tgggtaagca
    10861 agatattgtt ttgaaacttt tcatccatgt atggctcaat atctttctta tttccccatc
    10921 ttgctgagcc atactctttc ccctgtctaa actttttagc attttacctt tggtatagac
    10981 aataaattta attaaagcag ccattcctat gcccattaaa atatccgccg gatgaatact
    11041 tggaagaaaa ctcatcgtgt tgatctccaa tatcccttga aagattttat ctatgacatc
    11101 accaccggta tagcttctca catgatgggc aaagatgttt cctaaataga aaaatgcaag
    11161 atagggaatg ttttgcttta caaactttgt cttatcctgc accttaaata agcctttgat
    11221 gtcctttaat attttatcta tcataggctc tgctcctttt gtttattctt gattttatct
    11281 ttggaaacag agttcttagc catttcctta aacttctcaa tattcttgtg aatagattct
    11341 ttcctttccg ttttcttttc agactgtgct aatgcgtgct taaaggcttt atccatcact
    11401 ttcatatctt tggcttgaaa gaatacagag tattttcctg tttccttatc cttcatcact
    11461 gaaaacttaa caccataccg attaagttct tttttcagtt ccttaagctc cgcttcttca
    11521 acaggaattt cttcaagctg tccctttttt accatatctt ttagctttac ttcatttccg
    11581 ttagcattaa ccagcttttc aagtcctcca agtttttctg cttctttcat caatttcttt
    11641 aataagttca gaattaactt tcctgttact ttagcagctc ttacttccat attcagcgtt
    11701 tttcttgcta tttcttcatt gatcaagttc tctcacctcc attcagtaac ctatctttat
    11761 ttcgattcaa tttatctctt tgaataatct ttctaaaatc ctctttggat tgtgtcgtag
    11821 gaaaggttag tggtgaagat agtcggtttc tgctttaagt acctgttgtt gacaatgtta
    11881 tatacctgct ctttggcata gcttgtatct ctttctattc ccaagtcatc caagataaga
    11941 acggaagtat ttacaaggga ttcaatatat gcgttcttat caaaatcaaa tcctcccttt
    12001 tgcagctcat tgataagctg tgcaaaattt cttattttaa cgcctatttg atactgttca
    12061 ataaggctat ttgcaatgga gcaggcaaga taggtttttc cacttcctac tgagccgtaa
    12121 aatagcagtc cgatattttc ttttttcatc tgctcatagt cttttacaaa attctttgca
    12181 atgataagac tttgattttc ttctccctga taattttcaa aggtgtatga ccactgaata
    12241 atagagttaa agcagttctt ttttaatcgt tctatttcca tctgcttttc tctttctttt
    12301 tttcttgcct ctctatctct atcgcatttg caagaaatct taaatatcat cttgttatca
    12361 aagaactcca tcacttttct gtcttttctt tcatgacaaa ctttacaaaa ggcgtgtccg
    12421 tccttgatat attctttttc aggatcgtaa gaatactcta catcctctat cattactttt
    12481 tctaattctt ttatcatagg tgttctcctt tatcatattc ttcccatgtc gggatatttg
    12541 atgttttcac ttctttgccc cttccctgat ctttataaaa ccatgaaagg attgttgcct
    12601 tatggtcttt ataggtcttt ccggtgcttt taatatatgc agataatctc tcaatataat
    12661 tatcaagctg tgagttcatt atgatttgta agtctgatat atcttcagca gctaaaaaca
    12721 cattttgaaa tgttccaagc ccgttttcac taaaattata ttctctctta ctatacttac
    12781 tcttattatt ctctatatag ttagagtcaa ggttcttaac ctcttgaagt tcattttctt
    12841 tacttctgag gttaaaatct tttacttctg aagtaaaatt ttttaacttc tgtaagtcat
    12901 cttcttttac ctgaaatatg ctcataaaat ctttgacata aatgatattc ggctttccaa
    12961 gtccaagccg tacccgttca atcagtccaa ttcctttttt actatctaat tcatctaatg
    13021 tttttatggc agtcggcttt gagatatttc ttcttttcat aatttcttcg actgtgaaat
    13081 agataaatac cctgccttcc ttatcaatcc agttattctt aaaggacatt cctgtccgtt
    13141 taagaagcat tgaataaagg ataattgctt cagcggataa tcctttaaat tcttctccat
    13201 caaccaatat ctccggtact tttaagaaat taaatctttc cgcttctctg ttataaaaat
    13261 agtcaaagtc catcgcttca cctccctcct taaaaatttg caaagaaaaa gacgatagtt
    13321 tttctctatc gcctttggta accattttta tgaaattttt tagattgatt ttattgcttc
    13381 attgattcct ttaaagaatg ctataactgc tgctccaacc atcggtattc cataaggact
    13441 taacaaaaat cctaatacta atgcctcaat gccaagtgat atatcttttt gcataaatga
    13501 tcctattgca gcaactatac acatcagcat taagaaatac agaatagttg ttcctatgcc
    13561 aagtataaat gtcagaaagg cagtaaggac actaagtagc aagctgaatg gaaacaatat
    13621 tatttttatt atccacctca tataatacct ctcctttctc ttaaatcatt ttaaagtgcc
    13681 ttaacgcatc cataatagct ttttctttct caggtgtaca ctgcggaata acttgcttat
    13741 ctttttttga tttattgtaa ttctctctaa gttctattcc acattttctt tttatctgtg
    13801 ctatatatag tgttgaaact ttaaaaccaa atttttctaa tatatactct ttaattttag
    13861 cataggtagc cttgctttct gcacttgtca aatcaagttc atcaagctct atttcaacac
    13921 ttatatactt atcgacatta agtttggaca ataatgctac cgtctcgaca tgatgtgtca
    13981 ttggaaacaa gtctactggc tggactttct ggagtttata gccgagttcc tcgtagcgct
    14041 tgatgtcacg cgccatggtg gcggggttgc aggatatata ggttattttg tcaggctgca
    14101 tcgctgcact ggccttgata aagctctcag ttagtccctt tcgtgggggg tctacaatga
    14161 taactgttgg ctttatgccc tcctgacacc agtttgccat cgcattttca gcgctgtcag
    14221 cgacatagta ggcattggta ataccgttta gcgctgcatt tttctcggca tcacgcactg
    14281 ctgcttcgat cacttcgaca ccgtatactg ctttgacttc tttagcaaag gatagcccga
    14341 tggttccaat gcctgaatag gcatcaatca ccacatcgtc agcggtcaat tcagaaaaat
    14401 caatagctgt ttgatagagc ttttcagcca ttgttgtatt gacctgatag aaggactgag
    14461 cagaaataca gtattgattg cccaagatcg tatctgtgat tgtctctttt ccataaagcc
    14521 ttgtaaacgc cttaccaaag ataacattag taggcttgtc attgatattt tgcaggatag
    14581 aagtaatcgc tggaaattct gcgacaaggc tatcaatcat ctggttgata cgaaagattt
    14641 taggtcgtgt tgtcactaaa accagcatga tttctcctga ataatgccca cgacgaacca
    14701 caagatgacg aatcaggcct gactgctcct tttcgtcata gggcttgatg tcaaaacggc
    14761 gcaaaaggtc gcgtgtaaag gcaatcaagc gatcaatttc cttatcttga atgtaaaaat
    14821 cagaaatcgg cactagctca tgagaatgct tacggaaaaa accagtctct agctgaccat
    14881 tgacacgacg aacaggaacc tgggctttat ttcgataagc ataaggatat tccataccaa
    14941 ttgtttcttt gacctcaaca ttgctaatcc ctgcaatctt atagagacta tcctgaacct
    15001 gcttttgctt aaagagcagc tgctgcggat aaagcaagtg ccccaaatca gcaatacctg
    15061 tacgcagata ggtcacatcc agcttttttt gacgcatcgg tgaggttgtt agataggtct
    15121 ctaccttgcc aaagccactg tttttattga cctttaggac acgcatctga atgatctcac
    15181 ctggaagagc attttcaaca aagaaaacaa agccttcatg cttagcgatt cctaagccat
    15241 catggcttaa atcagaaatt tccacctgaa caatatcgtt tttacttaac atttactttc
    15301 cttttctttt actacactaa tcactcaaaa aagaagagca accatcgtta cccttcatta
    15361 tagcatatct tagcgtaatc ccagcttaga taatcgattt tgatacttag caaaatcaat
    15421 aaagagagcc tgaccaccat acatgtcata ttcatcaatc caatccccat tttcaggaat
    15481 cgtcacatgc tccacaccgt ttttgccatt agtcaagacg gacactccat ttttaaggac
    15541 aaatgggaag gagacattgg ttgaggttag ggcataaatc ttaccaatag ctgctgagcc
    15601 cgtaaagagc ttggttggat ccttgatttg agacatgata gcagccatca cctgctgctg
    15661 acgtacggtc cgaccaaaat caccctcatc gtcctttcgg aagcgagcat agttgagcag
    15721 ggtacgacca tccatttttt gctcaccaac cgttatggtt tggttgggaa ccactccgtc
    15781 tttcattcgt aaatcatctg gtacatcaac agcagcgact gcttcgccat ttacagtagc
    15841 aaatttggca tcaatggtaa caccatctgg aaacagtgtg tcaatagcct cagcaaaggt
    15901 ttcaaagtca accatgacat aatatttaat gtcaatatca aaattatgct tgagtgtctg
    15961 acgcacaaat tctgctcctt gatgattttc ctgctctcct aaattaaagg aggcgttcaa
    16021 ttttaaatca taggaatcct gattattata gctatagcca ggaatattaa ccaaggtatc
    16081 cctcatgaag gagaccattt tgattttatt ctccttattg ccaacattaa ccaccatgat
    16141 tgtatctgtt cgagcatctg ttgagccttg cgtaatcctc tggtctgagc ctagaattaa
    16201 aatattagtg ccatcgctag tatcctgacc atgaaagacc tgcgaaactg ctggcttata
    16261 attggccttg ttagtagaca cgtccatcat tcccttgaaa aacatgaaag ctatccctgc
    16321 aacaagcagc agcaacaaga aaaagagtat tctgaaaaaa cgtctcagac gtcccttctt
    16381 ttttttcctt ctaccctttt taggcatagc ctcaggcgca agctcctcat agatcgcctg
    16441 atctgggtca tcatagaagt cctgctgagg ggctagtatt ggcttttgct gatgcctttt
    16501 gctacgtctt tctgatcttg gataaagagg caggccatta ggcccagcct gctgctcatc
    16561 actcatatca taagcatcag cattatcctg tgaagcttga gcataatcgt cacgcccacc
    16621 cctagtataa tgagtcaagg agcgctgaga acgagaaggc atagcccttg actccatctt
    16681 tgactttaaa aaggtaaatt ctctgcgttc agtctcagtc aaataattta aatttcttaa
    16741 taaataaaaa tatcgtaatt cttcgtggtg gcttagacca cccttttggt atctcgtcat
    16801 gctcttccaa ctcttagtat tctaatacaa tttcttctat tctttgtcta atgattctat
    16861 tataacctat attaacgaga ttgtcctcta aaatcgttag aattcaactt tatttcaacc
    16921 tatatattag cttttcatac ctaatcatta agaaaagctg ggctgcgaat aggaggccaa
    16981 aagtctaatc ctcagcagtt acgacatatt ggcaatgatt gctgcaacct cctttggtgt
    17041 tctatgctca acattaatca ctttgtctgc caatccctca tacaaggcca tgcgctgctg
    17101 aaaaatagca tagagttctg cttcagaatg atttaaaaac agtggtcttt ggcatagcct
    17161 atctttttta agccgatcat acaaagcctc aaaggaggct gttaagagga tattattttt
    17221 gtgatttttt ctgattaatt ctcggtttgc cttactaagg acaacacctc caccagttga
    17281 tacgatagtc tcattatcaa gtgccagcac ttcctgtaag gtatctgact caagctttct
    17341 aaaggctgct tcaccacgat aggaaaaaaa tgctgatatg ctcatgccta ttttagcctc
    17401 aataagccta tccatatcca aaaaatgctc atctaattgg gctgcaactg tcgtcttgcc
    17461 aactcccata aatcctaata gcagcttagt catgccataa cctctctaaa tccttaaaaa
    17521 agtcaggata agaagtcagg atagcttctg ctcgctctag ggtgacctgt ccttcttcaa
    17581 ccagtagggc tgcaatagct gtcatcatgc caattctatg atctccacag gtactgacag
    17641 ctgcaccatg taatggtgtt ttgcctctag tcaccatacc gtcctctgtc gcctgaatat
    17701 cagcacccat ctgtcctaat acatcagtaa cagcctgaat gcggtcagtt tccttgaccc
    17761 gtaattcttg agcgtccctg atataagtcg ttccctgtgc ctgagttgcc agcaaagcaa
    17821 taacaggcaa ttcgtcaatc aagcgaggaa tcaagtcacc agaaatctca atgcccttta
    17881 gggtggaata agacactttt agggtagcag cctgcctgtc cttatcaaca gcctgatagg
    17941 agatacgacc acccattttt tcaatgacct ctaaaagacc tgtccgcgta ggattaatcc
    18001 ctacattttc gagcacaaga tctgaccccg gaacaatcag accagcagct aaccaaaagg
    18061 ctgcgctaga gagatcgcca ggaatctgta aggtctgtcc ctgcaaacgc tgcggtcctt
    18121 tgatactgat ttgctttcca gctactgaga gctttcctcc aaattgttca atcatctctt
    18181 cggtatgatt tcttgtcaat tccttttcaa ggataacagt ctctccctgt gtctgcaaag
    18241 cagctaataa aatagcagac ttgacctgag cagacgctac aggcagctga taatggatcg
    18301 gccgcaactc ctgacagccc tttacaatta gtggtggaag ctctttttct ccttgaccag
    18361 atagctctgc tcccattaga gacaatggta tggtaatacg atccatagga cgccttgata
    18421 ggctatcatc tccaagcagc tgcaccgaaa aatcctgtgc tgctaatagc cctgcaagca
    18481 ggcgcataga agtacctgaa ttgcccatgt ctagaggctt ttgagctggc tttaggcctt
    18541 taaaacctct tccttcaatg attaaactat cagctgactc gtaaatggtg acacctaggt
    18601 ctcgaaaggc ttgaatggtg gctaaaacat cttgccccct taaaagacca tgaatcaccg
    18661 tttgcccctc tgctatagca ccaaaaatga ctgcacgatg gctaattgac ttgtcacctg
    18721 gtacccttag acgtccccta agcgccttag cttttgtttt taatttcatc attactccta
    18781 tttttagtac accagcatta gctcagcaaa gcaaataaaa gaaaatgaag taaggacaag
    18841 ggcccttacc ccatcaacta atcaccaagc accgtcttgt ttttcattct aagacaagcc
    18901 gctatttctt gggcggcgca ccatcattgc ctaatgtctt tttgatgaga gaaacaacat
    18961 tgccgctgcg cccctctaat ttgccgatgg atagctcttg ataggtagcg ttaaaaaccg
    19021 cccccataat caatatcctt gccaggaaaa taaaccatag catgatgata aaaatcatca
    19081 ccgaaccaaa ggttttaata tcgaccattc gctccacatt atgcaccaca taattaccaa
    19141 ccatattgct caaaaaaatc atgacaaagg tggtaaaaaa tgttcctggt aagatatacc
    19201 tgattttctt gattttgata tttggcaaca aaaaataaag caacatcaga ccaacaaata
    19261 taatcagtat cgtaatcggc tgaatcagga acaaaaagag cgtcgtgatg ttatcattta
    19321 agtgataatg cctatccagc acctgaatcg ctgccttaga aaaggttgaa aaaatcaagg
    19381 caaaggtcaa caaaaacagg atcagcaggc tcgtcagcaa gcctaccaaa tgaccgagca
    19441 aaaagtcacg atgctcagaa gcatcataag ccttattaaa ggccttttgc agagaggtta
    19501 ggcttcgcga cattgtccaa agccccgtca aggtcgctac tcccagcaca ctgcctgatg
    19561 gcttagaaaa aatattaacc acaatggagg aggcagagcg ataaatatcc ttaggcagct
    19621 gctccttcat taagcgtaat aaatctgaaa tatcaatatt taaataagga aaaatattag
    19681 ccgcaatgac aatgagtgga aaggctgtca aaataaggta ataagcaact gcaatcgctg
    19741 acaaatccat ctctgcactc tgaaaatggc gcataaaggc ttggattggc tcatattgcc
    19801 attttgatat gaccttgtcc aagaatttct ttattgacat tctaataagt tctttcttcg
    19861 ccctgactag ttaaaatcac tggaccatcc tttgtaatca caaattgatg ctcatactgg
    19921 caggacaagc caccatcaag tgttttatgg gcccagcctg ttttcatatc tgtattaatt
    19981 tcccatgtgc cagtattgat catcggctct acggtgagca ccatgccctc cttcagacgt
    20041 agtcctcttc ctgctgtacc atagttaggc accatcggct cttcgtgcat ggttggtcca
    20101 acaccatgac caacaaggtc tcgaaccaca ccgtagccat gactttcagc atattgctgg
    20161 actgctgcac caatgtcacc aatgcggttc cccacaactg cctgctcgat cccacgatac
    20221 atggcttcct tggtcacgtc catcagcctt ttgacctcat cagacggtgt acctacagca
    20281 taagcccagc aggaatcagc caaaccacct gtataagatt ctgtccactt cttcatttct
    20341 gccacattat caaaatccaa ggccgctaca tcaacgacag ccttatcaag tggctcactt
    20401 agcaccatat ctaccttaag caaatcccct tcctgtagaa tataatggcg cggaaaagca
    20461 tgtgcaacct catcatttag cccgcagcag gtagcgtaag gataatccat taattggcca
    20521 tcaacaccga tctgtaaagg aagcacattg tcctccttgc agcgcctgcg cacatattct
    20581 tcgacctccc acatgtcaac cccaggctta atgatctgtc tgaggccaat gtgaatccca
    20641 gcaagaaagt ctcctgctct atccatagct tctatttcac gcgcagattt taatgttatc
    20701 attgtttttg tttctcctct aattaagctt agttgtaata atggctttag caatcacctg
    20761 atcatcaacc atgacctcca tatcaagtgt actgcttctt ctattttcag ttataatttt
    20821 agggtatatc ctcaattgat catcaatttg gacagcatgt agaaagtata tcatcatttg
    20881 ctcgataatg atattttttt ggtgtttttt cgttagcact ctgacactga tttcctttaa
    20941 gaattcagca accactccat ttgacagatt gccagcacta tcaatcatgg taggctcaat
    21001 catgacctga taataatcca aggtctcctc aaggcttgat agcatttgct ggctataggt
    21061 gtaaagattt cccggctggt gattcggcag gttttccata gcctgtcgtc tggtaataat
    21121 ccccagcaga aaatgatgat catcaactac tgggagcatg ttcaaatcct caaagatcat
    21181 tttttgacta atattagcca ggctagcatt gggctttgca gtgataggat ttggagacat
    21241 cacctgctca agtctagtct cagcaggctg atccaccaca tcacgcatac tgaccacacc
    21301 aaccacctga tcaagcgcat ctacaattgg aaaccttact tgacctgtct ttttaatcag
    21361 tgcattaaat tcctcgacag tgtctgtctc ataaaggcag ccgtattctt caactggaat
    21421 cagaacctga gcaactgttt ttaaatcagt cttaatgcga atattagaca aggcatggtt
    21481 aatcatcgtt gccactgtaa aggtatcgta atgtgtcacc ataaccggaa taccttggct
    21541 atcagctgtt tcaataacct gcttagacac cggaaagcca cccgtcacta agatagcatt
    21601 gtgattttta agggctaaca gttggatatt ttcacgatcg ccaacaatca aaagccctcc
    21661 tttgatcaaa taacggtgaa tattttgctg ggtcatcgct ccaatagaaa acttgctaaa
    21721 ctcatgtccc aaaccagcat gaccggctaa aacctcagaa tcactgatcc ttgcaatttc
    21781 ggcataggtc aaacggtcaa tacgaacccg tccttttttc tcaatgcgga cagtaccact
    21841 acgcggcttg gtctcaacaa tcccccgatt ttcagcctcc ttgatcgctc tataggcagt
    21901 accatcacta acctttaaat gatttgaaat acttcggacg ctcacacgct ttccaatagc
    21961 aagtctttct aaataatcta aaatgtcttg atgcttactc ataatgatac tcacctatcg
    22021 ttagttgata ttctaaataa tctcgtatgt gatgactatg ccgatcactg cccttaaatt
    22081 gctttgttaa tcgaaagccg gctttttcag caaccctctg gctggccttg ttttccagat
    22141 gtgtcacaat gatcagctgc ctcaagccaa actcctgaaa agctaaaaag gtaagcgtct
    22201 ttaagacctc ggtcattaag ccctgtcccc aaaagggctg cgctaaaaaa tagccaatct
    22261 cagcacttgc ctgctgctta tcatattttt ctagtctaat agagccaagc atgctatggc
    22321 tggtcttatc ctctattaac cagactccca agggctcttt cataaaagca ttgaccatta
    22381 agaaatcact ctcagccttg gtcatgctct ctggaaacac aaactggtaa tggctgttat
    22441 gactgatcat atcataaaac ggctgatgat ctgcatattg aaagggcctc aagagcagtc
    22501 gttgcgtctc aacaaaagca aaccttgcta gctgtgtcca aatatccata gcctcccctt
    22561 caacatgcct gtaatactat tattatagca gatatcacct aaacattcta taactgtcat
    22621 gagttttgcc atgatgatca taataacctg acaagccata tcatagctca atcagactct
    22681 aagctgttaa actattacta acagtcaaaa ccaaaaaaga gaagaccgtc tgatcttctc
    22741 ttgctatctt atctgctaat gcttaaatgg gctacatcat agaaaagtcc tatgagtaag
    22801 ctcatccttc taaggctaaa catgcttcca taaatacact gcttagtcct gctgacgctt
    22861 tgaagtcact gctaaagcac ctgcactcgc cataatggca agagccgctg ctgtaaagaa
    22921 tggattagcc ttctcaccag tcgttggaag agtcttagcc ttttgcttat ctttttgctt
    22981 agctggtgct gtcttagttg ctggtgtaag cggtgtcaac ggaagagaag ctgatggctt
    23041 ttctggatca gctggactct cctctaaagc ctcagtgact gtaaatgtct ttgtagcagc
    23101 gtcataagcc cattcaccag taacgccatt gtcattggca tattgcctga aggtctgctc
    23161 ggctgtggct gcgtctactg ccttggtagc tgtttcacct gagaaggtaa cccccttaat
    23221 aacaagccta taggtggtca aagctggtgt taattctgcc gcctcaatag tctcagctac
    23281 aggctgttca gtgactgtaa atgtctttgt ggcagcatca taagcccaaa cgccgtctac
    23341 accattttta ttagcatagt ctctgaaggt ctgctcagct acagctgcgt ctactgcctt
    23401 agtagctgtt tcacctgaaa aagttgctcc cttgatgaca agcttatagc tagtcaaggc
    23461 tggtgttagt tctgctgcgt caatgacctc agaactcggt agagctgata aaatctctgc
    23521 cttaagcgca ttgacacctt caacagtttt ggctttgttg attaaggtca catagtaatc
    23581 actaatgcca tactgcttta gttcattgat agcagcttct ttagcctcca acaaggctgc
    23641 tcctgtaatg tccgcaatag ctgtatgagc atcattaatg gctgcattca cttgatcaac
    23701 tgaagcagca tctgccacct tagctgctgc agcaactaga gctagctgaa ccttttgatc
    23761 gcttttgtgc tgatcactta aggcattgat tgttctgtaa gcctcacgtc ttgcttcatc
    23821 aagctgaaca ccagcaacag ctgcctttgc tttgtcaaga gctgctttag cctgatcaac
    23881 agtatctgca gcaagtgcct caactccagc attagcaaga acagcctgaa gctcttgatt
    23941 gtcagcgtag tcatcactca gctgattgat ttccctaaca gcttctctaa tgaaggctgt
    24001 tgtaggctct aacactgttg ctgcgtctaa agcacccact gaagtcgttc caaccagaaa
    24061 ggctgccgac actgaagcta aaccaacagc tgattgacgt aaaaagtagg ataccttttt
    24121 gtttttttcc atttttcctc cctcgctttt tgtaaaaaaa actttgacac taaaaactat
    24181 taatgtcact tctattatac tacgcc
//
LOCUS       DARYYD010000031        23452 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.031, whole genome shotgun sequence.
ACCESSION   DARYYD010000031 DARYYD010000000
VERSION     DARYYD010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23452
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.031"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..90
                     /locus_tag="TV188_001198"
     CDS             <1..90
                     /locus_tag="TV188_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534554.1"
                     /translation="KYVIIATHDPAVYNKVDVIIDLKDIGSEI"
     gene            87..596
                     /locus_tag="TV188_001199"
     CDS             87..596
                     /locus_tag="TV188_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534555.1"
                     /translation="MKKKAYMTLILLIGILAIFLVGKQVIKKENPNKPTVDLTVYTIS
                     SSDTQKWNKVRQLETEEAIYLIRVKEAASSEEIFSNIIADGAAMGFGVSEEDVKQFNN
                     HLENTIEDSKNNKLIEMEFFDFSNNNKGFVVANFDYGKKEFNAQKKEKKALYKKLYEA
                     FKEKNHQSR"
     gene            1114..1911
                     /locus_tag="TV188_001200"
     CDS             1114..1911
                     /locus_tag="TV188_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1534556.1"
                     /translation="MVKLIATDMDGTFLREDGTYDKERLAALLPKLREKGILFTVSSG
                     RSLLAIDHLFEPFLDDIAIIAENGSVVQYKRDILFADVMTKQQCHDIVEKILANPYYN
                     QSGILFSGQKAAYVLKGATEDYIQKMHYYYENVQLIDCLQDIVDDTVFKASTTFTGET
                     VLAGSDWLNQELSYASAVTTGFDSIDIILKEVHKGFGMDQLCQHLGILPEKTIAFGDN
                     LNDYQMLSFAGQAIATENARPEIKAISDQVIGHCNDSAVLTYLEGLV"
     gene            1912..2739
                     /locus_tag="TV188_001201"
     CDS             1912..2739
                     /locus_tag="TV188_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1534557.1"
                     /translation="MTRIKLLALDLDGTLYNTEKIVSDENKKALAAAKEKGVKVVITT
                     GRPLKAIGNLLEELDLLGEENYSITFNGGLVQRNTGHILDKSALSLAEVYDIHQQLAA
                     VGLPTDVISDGTVYSLSGNDGRRSQYHLASPLLNFVSLKSFAELPKDITYNKIVTVTD
                     PKVLDQQLARLPKTIFEDFEAFKSRDIIFEIMPKGIHKAFGLDLLCQHLGLEAKHVMA
                     MGDEANDFSMLQWAGLGVAMANAVDQAKEVADAVTTLTNDQSGVAEAIWKYILNEEG"
     gene            2739..4196
                     /gene="ftsY"
                     /locus_tag="TV188_001202"
     CDS             2739..4196
                     /gene="ftsY"
                     /locus_tag="TV188_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEL1534558.1"
                     /translation="MGLFERLFGKKDKTKVAEQEAATTEVLSEDITSKDTIESEKEAL
                     SDTNAHAVAADVVSRTDDTSKQAELSDEAASEQAEGLDPAARGAFLLEREPELELAAT
                     DDKTLDQAGESLSQHEAMEEAKHDRAKSEHSNESADASTEDQAETNAEYQVAAQAPAG
                     SADQPAEEGQKQETLSAESDQEKYKRSLKKTRTGFSARLNSFFANFRRVDEDFFEDLE
                     ELLILSDVGVHVATTLTEELRYEAKLENAKKPEALKRLIIDKLVAIYEGDGRYNEAIH
                     YQPGLTVMLFVGVNGVGKTTSIGKLAYRYKQEGKKVMLVAADTFRAGAVAQLVEWGRR
                     VDVPVITGPEKADPASVVFDGVERAVAERADILLIDTAGRLQNKDNLMAELEKIGRII
                     KRVIPDAPHETLLALDASTGQNALSQAKEFSKITPLTGLILTKIDGTAKGGIVLAIRQ
                     ELDIPVKLIGFGEAIDDIGEFHSEDFMKGLLEGIL"
     gene            4485..5324
                     /locus_tag="TV188_001203"
     CDS             4485..5324
                     /locus_tag="TV188_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1534559.1"
                     /translation="MIIKRVLNHNAAISTNHQGLDILLMGKGIAFKKRIGDHIDSEAI
                     EASFVLKNSDNMNRFTELFIAVPQEVVACSERLINLGKIKLGKNLDEILYINLTDHIH
                     SAIERHKQGMIISDPLRWEIRRYYPDEYAIGVKALEVIASELGVALAVDEASFIAMHF
                     VNASLDNPFKEPHRMTEIVSYIEQKVKADFKTELDEVSIDYYRFITHVKLFAQRVLSG
                     MAYDDDETDLLLMVKDKYPEEYHCVRQISHHMKKAYHYQLSSSELLYLTVHIKRLVKN
                     VKE"
     gene            5329..7191
                     /locus_tag="TV188_001204"
     CDS             5329..7191
                     /locus_tag="TV188_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HEL1534560.1"
                     /translation="MTYQETAKAIFEAVGGEQNIQEVTHCITRLRLVLKDDKQVVDQK
                     IKLIPNVIGVMRQNGQYQIILGNDVNNYYKAFMTLGQFHETDMSSSAGQKQSMIEGLI
                     ETIASVITPLIPALLGGGMLKVVGILVPMLGLAGTDSQTVAFINFFGDAAYYFMPIMI
                     AYSAAARFKVTPVLAATVAGILLHPAFVTMVATGKPMALFGAPVTPASYGASVIPILI
                     MVYLMQYIEREVNRFVPSVMKSFLQPTLIIFISGFLALVVIGPLGVIIGQGLSNSLLA
                     IYHIAPWLALAILGAIMPLVVMTGMHWAFAPIFLAASVATPDVLILPAMLASNLAQGS
                     AAVAVACQSKQKQTRQVALAAGLSALLAGITEPALYGITLKFKKPLYAAMISGGLVGA
                     YIGFVNIASYTFVVPSLIGLPQYISPTSSANFTNALIAAGLTIALTFTLTWFFGIDEE
                     VDQEGSADSDSTPVKSGLSAKQSIYAPMVGTVLPLSEVPDETFSSKLLGEGLAILPNE
                     EYVYAPFDGEVITLFPTKHAIALKNAKGVDVLIHVGIDTVELKGQGFEQLVKAGDTVK
                     QGQPLLRIDLELIGSKGYSLVTPFVVTNSSEQLEIIVNDNKEHITQHDVALVIL"
     gene            7218..8639
                     /locus_tag="TV188_001205"
     CDS             7218..8639
                     /locus_tag="TV188_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEL1534561.1"
                     /translation="MVCFPKDFLWGGAVAANQVEGAYLTDGKGLSVQDVLPEGGLGDY
                     TAEPTAANLKLEAIDFYHRYKEDVALFAEMGFKVFRTSIAWSRIFPQGDETEPNEAGL
                     QFYDDLFDELIAHGIEPLVTLSHYETPLHLAKVYNGWTDRRMVGFFERFATTVMQRYK
                     NKVKYWLTFNEVNSILHMPFTSGAIMTPKEKLTPQELYQAIHHELVASASVTRLARLI
                     NPAFKIGCMILAMPAYPMTSDPRDILAAKQFEQRNLLFSDIQVRGKYPSYAKSFFKEQ
                     HIDIQFEPGDSELLAQHTVDFLSFSYYMSVTQSHHPDHYQRGEGNILGGLVNPHLPSS
                     EWGWQIDPIGLRITLNDYYDRYQIPLFIVENGLGAKDKLVQTKDGHWTVQDDYRIDYM
                     RQHLLQVAKAIEDGVDIMGYTSWGCIDCVSMSTAQLSKRYGFIYVDRHDDGSGHLTRY
                     KKKSFAWYQRVIETNGRSLSEES"
     gene            complement(8824..9639)
                     /locus_tag="TV188_001206"
     CDS             complement(8824..9639)
                     /locus_tag="TV188_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEL1534562.1"
                     /translation="MIRFLILAGYFELTMYLELSGKLNQYINIRYAYLAYISMVLSFI
                     LALVQLYTWTKNIKLHSHLKGKVAQLTSPLILVFPVLVGLLVPTVSLDSTTVAAKGYT
                     FPLAAGASKTGVSDDGTTIQYLKPDTSLYFTKSAYQKEMLNELKKYQGKSAITITTDN
                     YMEVMELIYLYPDEFVDRTIQYTGFVYNEPGHDSYQFLFRFGIIHCIADSGVYGLLTT
                     GNQESYANNTWLTVKGQLHMEYDKTLEQQLPVLQIEEAHQAPEPDNPYVYRVF"
     gene            complement(9639..10541)
                     /locus_tag="TV188_001207"
     CDS             complement(9639..10541)
                     /locus_tag="TV188_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEL1534563.1"
                     /translation="MSLFSNLPPSVLQWFAIFLSIIIEALPFVFLGTILSGCIEVFVT
                     PDLVQRYLPQNKWLRILFGTFIGFVFPSCECGIIPIINRFLEKKVPSYTAVPFLATAP
                     IINPIVLFATYSAFGNSLRFLMLRLLGAILVAVSLGIMLAFIVDENILKESTQPVHCH
                     TYSHESLPKRLYLALAHAIDEFFDTGRYLVFGTLIASAMQIYLPTKVLTAIGHSPLTA
                     ILVMMLLAFILSLCSEADAFIGASLLSTFGVAPVLAFLLIGPMVDIKNLMMMLNSFKG
                     AFIVQFISVSAVMITIYCLLVGVL"
     gene            complement(10582..10737)
                     /locus_tag="TV188_001208"
     CDS             complement(10582..10737)
                     /locus_tag="TV188_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534564.1"
                     /translation="MAITHKKNDQLEKMMAGFASIPDFDKPLELNQDGKLVTEKPKPQ
                     VKTAKQD"
     gene            10909..11631
                     /locus_tag="TV188_001209"
     CDS             10909..11631
                     /locus_tag="TV188_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003104099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1534565.1"
                     /translation="MTKRVLLVDDEEPILRLLDYHLAKEGFVTEMVTDGRTALALAER
                     EPYDFIVLDIMLPQLDGIEVCKRLRAKGSKTPIMMVSAKSDEFDKVLALELGADDYVT
                     KPFSPRELLARVKAILRRTEAEISGDGEERREPFYTMSQLRLYPERHEVYKDKELLPL
                     TPKEYELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAP
                     QYIQTIRGYGYKFKELKNDRTS"
     gene            11615..12940
                     /locus_tag="TV188_001210"
     CDS             11615..12940
                     /locus_tag="TV188_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEL1534566.1"
                     /translation="MIGHLRRLSMLLGLCLLAALGLIWQGPHQVLTLVVLCTGLVASF
                     YVLSMLFRWEREFRALHHHLLTASDHFLLVGQADLSAYAKQLTELKSDLLQKEARLKA
                     LSKNVEAVTSHLTMGMLLVSNQRELLLTSKSLPAYFPEAKPPFVVLEDLKRMDLIALV
                     NQVFDQKQTLKKELTGLHDGDLILEVTLVPIFNQSHVVKEILVLLYDLTAIRHYERLN
                     LEFIANASHELRTPVTSIKGFAETIKEMPDDETSLKEDFLDIIYNESLRLERIVEHLL
                     TLSKANKTPLDLTEFQLRNFLLYTGQSMRPQLEQKQLELSYALEDSIVVTSDQYLLSQ
                     IMLNLLSNAIQYTDNGGRIQLSSQRVAGGVAITVADTGIGISQIELDRIFERFYRVNK
                     GRSRQSGGTGLGLAIVKELSQLLGGQITVTSQLGEGSQFTLFLPEAINK"
     gene            13099..13971
                     /locus_tag="TV188_001211"
     CDS             13099..13971
                     /locus_tag="TV188_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HEL1534567.1"
                     /translation="MTIKKMLIMAAIGLSGLGLAACGNNSADAGKAADRIDLVSRENG
                     SGTRGAFTEMTGILKKDGDKEIDQTAKTAIIQNSTEGVISSVKGNSRAIGYISLGSLN
                     SDVAALKVNGVKASRETILEGKYPLQRPFNIVWSSDLSGVGKDFITFIDSKQGQEIVR
                     DNRLIEAKTDAPAYSSKGLSGKLSIVGSTSVSPLMEKLAEAYKKENPAISIDITSNGS
                     SAGITAVKEKTADIGMVSRDLTTEESKGLIDDAIALDGIVVIVHKDNKVSNIGIDVLA
                     DVFSGKLTSWDKVK"
     gene            14041..14904
                     /gene="pstC"
                     /locus_tag="TV188_001212"
     CDS             14041..14904
                     /gene="pstC"
                     /locus_tag="TV188_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1534568.1"
                     /translation="MNKQAFKEDFFKVIFFLSAAMAIIAICLICIFIFSNGLPFIAKY
                     GMRAFLLGNDWSPSNQPASYGILPMIAGSFVITLGAMVIGVPTGILTSVFMVYYCPKA
                     CYGFLKSAVNLMAAIPSIVYGFFGLQVLVPWIRSFAGNGMSVLTASLLLGIMILPTLI
                     SLSESAIRAVPKAYYSASLALGASHERSIFRVILPAAKSGLFSALILGFGRAIGETMA
                     VILVAGNQPVLPSGLFEGTRTMTTNIVLEMAYASGQHREALIATSAVLFGFILIINAC
                     FAYVKGKSAHD"
     gene            14897..15712
                     /gene="pstA"
                     /locus_tag="TV188_001213"
     CDS             14897..15712
                     /gene="pstA"
                     /locus_tag="TV188_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1534569.1"
                     /translation="MTNYLLKALVYLLSLLTFGSLFLIIAFMLIKGLPSLSLSLFSWT
                     YTSDNVSLMPSIISTVSLVLGTLVLALPIGVFAGFYLVEYAKQDSLWVRAIRLAADTL
                     SGIPSIVFGLFGMLFFVVFFGLQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDHLRQ
                     ASLGLGAGKLRTIFKIVLPAAMPGILAGVILAIGRVVGETAALMYTLGTSTNTPTSLM
                     SSGRSLALHMYMLSSEGLHVKEAYATGVILLITVLLINALSSLLSRRLVKGVV"
     gene            15714..16466
                     /gene="pstB"
                     /locus_tag="TV188_001214"
     CDS             15714..16466
                     /gene="pstB"
                     /locus_tag="TV188_001214"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1534570.1"
                     /translation="MGAFSTKQLNVFYGAFQALKDISIDIPENQITALIGPSGCGKST
                     FLKTLNRMNDLIPSCRIEGEVLLDNQDIYAKAINLNSLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGLKDKKTLDQLVEQSLRGAAIWDEVKDSLKKSAMSLSGGQQQRLCIARA
                     LAVAPDVLLMDEPTSALDPISTLKIEDLVQQLKQDYTIIIVTHNMQQASRMSDKTAFF
                     LTGDICEFGDTAELFTKPKDKRTEDYISGRFG"
     gene            16742..17068
                     /locus_tag="TV188_001215"
     CDS             16742..17068
                     /locus_tag="TV188_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534571.1"
                     /translation="MKKLLLTSAAALALATVAVSTTKVEAFSRGHVIEHTINDTKSLS
                     AARWGSRLQILNLLTRFKHKLGEDGFRSYNRQFRARVGAAKSVSEIDELYNKFEKELE
                     ELEDLT"
     gene            17236..19368
                     /locus_tag="TV188_001216"
     CDS             17236..19368
                     /locus_tag="TV188_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEL1534572.1"
                     /translation="MENMNHQNISEALGVTPKQISQVLTLTAEGNTIPFIARYRKEAT
                     GNLDEVVIKAIIDMDKSLTQLRERKDTILAKIEGQGKLTAALKEAIEAADKLADLEEL
                     YLPYKEKRRTKATIAREAGLSGLARLILQNAQDLETKAEAFITEGFSDPQAALAGAVD
                     ILVEAMSEDSRLRSWTYNEIWKYSRITSSLKEASLDDKQVFQIYYAFSETVSNMQGYR
                     TLALNRGEKLGVLKVSFEHHIDKMLRFFSLRFKEHNAYIDDVINQTIKKKIVPAMERR
                     IRTELTEMAEDGAIKLFSENLRHLLLISPLKGKMVLGFDPAFRTGAKLAVIDPTGKLL
                     TTQVIYPVAPANQAKIQAARVALAQLITDYQIDIIAIGNGTASRESEAFVAEVLKDFP
                     ETSYVIVNESGASVYSASELARHEFPELTVEKRSAISIARRLQDPLAELVKIDPKAIG
                     VGQYQHDVSQKKLSEHLDFVVDTVVNQVGVNINTASPALLAHVSGLNKTISENIVRYR
                     EENGEITSRAEIKKVPRLGAKAFEQAAGFLRIPNAKNILDNTGVHPEAYPAVKKLFQL
                     LAIKDLDEPARAKLQAVNLEEMAEQLTLGQETLKDIIADLLKPGRDLRDDFEAPVLRK
                     DILSVKDLAVGQRLEGTVRNVVDFGAFVDIGVHEDGLIHISEMSEAFVNHPSQVVSVG
                     DLVTVWVSKVDLDRHKVNLSLVPPRESD"
     gene            19355..19792
                     /locus_tag="TV188_001217"
     CDS             19355..19792
                     /locus_tag="TV188_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEL1534573.1"
                     /translation="MSLTDYVREVSLADFGKPFKHQASWNRRLRTTGGRFFPKDGHLD
                     FNPKILEEHGETVFRQIVRHELCHYHLYFEGLGFRHKDQAFKELLDQVDGLRYAPKLQ
                     SHQANYLYICQDCGQAYDRKRPINLAVFACGRCHGRLIEKNQS"
     gene            19856..20128
                     /locus_tag="TV188_001218"
     CDS             19856..20128
                     /locus_tag="TV188_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEL1534574.1"
                     /translation="MESKFYKQRKHKLVAGVISGLADKYGWDLPLARVLAALLIYFTR
                     FGVVIYILLAIFLPYKEDLLEERYGRGPRRRKDADVLNDEDEGWFW"
     gene            20406..21338
                     /locus_tag="TV188_001219"
     CDS             20406..21338
                     /locus_tag="TV188_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEL1534575.1"
                     /translation="MTVTVKMLVTKVKLDVVYATDDLLEKEITTSDISRPGLEMTGYF
                     DYYAPERLQLFGMKEWSYLTQMTSHNRYSVLKEMFKKDTPAVIVSRGLAIPEEMVQAA
                     QEEGIALFSSRVSTSRLAGEMSYFLDASLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDVFAKDEETLWGEPAEILRHLLEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAIYLENFEAGKVFDRLGNGNEEITFSGVSIPRIRIPVKTGRNVSVVIE
                     AAAMNHRAKEMGFDATKTFEERLTRLISKNEEGK"
     gene            21335..22114
                     /locus_tag="TV188_001220"
     CDS             21335..22114
                     /locus_tag="TV188_001220"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEL1534576.1"
                     /translation="MINPIAFKLGPLSLHWYAVCILVGLLLAVYLAAKEAPRKKMTSD
                     DIIDFILIAFPLAIIGARIYYVAFEWSYYSQHLSDIFAIWNGGIAIYGGLITGTIVLF
                     VYCYYKVLNPIHFLDIAAPSVMLAQAIGRWGNFFNQEAYGRAVSQLNYLPSFIRQQMF
                     IDGSYRVPTFLYESMWNLIGFVIIMVWRRKPRSLVDGDIISFYLIWYGCGRLVIEGMR
                     TDSLMLLGIRVSQYMSVLLIIIAIVFIFKRHRQKGISYYQE"
     gene            22136..22540
                     /locus_tag="TV188_001221"
     CDS             22136..22540
                     /locus_tag="TV188_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007892823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEL1534577.1"
                     /translation="MNLVGISLLIIALAFVALVIFLIVVLKKVSEAVDEAKKTITVLT
                     SDVNVTLYQTNEILAKANVLVDDVNGKMTTIDPLFVAIADLSESVSDLNVQARHLGRR
                     ATNATSNAAKVGKVALVGKVASKLFGKKEKRS"
     gene            22537..22962
                     /locus_tag="TV188_001222"
     CDS             22537..22962
                     /locus_tag="TV188_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEL1534578.1"
                     /translation="MSNFFKTLVIGVASGAATAYFLSTEKGKVLKARAQRAYEAYRQN
                     PEEYHQMAKEKGSEYSQLARHTFNDLKTRFESGDMTTDQVFDFIKEKTSQFVHQAKEA
                     ASEHDKADDVIIDLDEEDIIINYPEDDSEKEAASNKSEE"
     gene            complement(23088..23369)
                     /locus_tag="TV188_001223"
     CDS             complement(23088..23369)
                     /locus_tag="TV188_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEL1534579.1"
                     /translation="MPTPLEQRQLKQQKQEQVSQQKFQEFQDLNGHSSKLKELIFFAR
                     IAVFSLITVLFAFVLLVMNLAPVWAFLIASAISLAITSFLSKAITLLMS"
BASE COUNT         6731 a         4412 c         5567 g         6742 t
ORIGIN      
        1 aaatatgtta ttatagcaac acatgatcca gctgtatata ataaggttga tgttatcatt
       61 gatttgaaag atatagggag tgagatatga aaaagaaagc ttatatgacg ttgatattat
      121 taattggaat actcgcaatt ttcttagtgg gaaaacaagt aataaaaaaa gaaaatccca
      181 ataaacctac ggtagattta acagtctata cgatctcttc tagtgatacc caaaaatgga
      241 ataaagtaag acaattagaa acagaagaag ccatatacct aataagggta aaagaagcag
      301 catcttcaga agaaatattt tcaaacatca ttgcagacgg agctgctatg ggttttggag
      361 ttagtgaaga agatgttaaa caattcaaca atcatttaga gaatactata gaagattcta
      421 agaataacaa attaatcgaa atggaatttt ttgatttttc taacaataac aaggggtttg
      481 tggtagcaaa ttttgattac ggtaaaaaag agtttaatgc tcagaaaaaa gaaaagaaag
      541 cgttatataa aaaactatat gaagctttta aggagaaaaa tcatcagtct agatagattc
      601 attactcaac tctttagtaa caagaaaact tagtgacggg cttcaattaa gaattatggc
      661 aaataagcgt tgagagtatg gagataaaga agtttagcct ttaaaaacgg agctcagatt
      721 gactgttaaa acaagggtat gtcagatggc acgccctttt ttggtctacc tgtggtataa
      781 cgaaaggagt tatactggga tttgagttgc acaccccact cgggttttgc actcccttga
      841 aagtgaaatg gttagattgt atgttaaagt taattgcaac agaaattgga ataaggaaat
      901 tgatacaata gaacataaag aaagccttgg aataagggct caataatctc cacagtggag
      961 ttacccacta cagaaattat aaagccttaa aacaaggacg tgttaggaca ggcacgccct
     1021 ttttgtttag atatggtata atggaaaaag agatttttgg gagagctgaa tagctgaatc
     1081 agtatctccc taaaaaggaa atggttaaat tgtatggtta aattgatagc aacagatatg
     1141 gacggaacct ttttaagaga ggacggaact tatgacaagg agcgcttggc agctctgttg
     1201 cctaagctaa gagaaaaagg gattctcttt acagtttcta gtgggcgttc gcttttagcc
     1261 attgatcact tgtttgagcc ttttttagat gacattgcca ttatcgctga gaatgggtct
     1321 gtggtgcaat acaagaggga cattcttttt gctgatgtca tgaccaagca gcagtgtcat
     1381 gacattgtag agaaaattct tgccaatcct tattacaatc agtctgggat cctcttttca
     1441 gggcaaaagg cagcctatgt gctcaaagga gctacggagg attatatcca aaaaatgcat
     1501 tattattatg aaaatgttca gcttattgat tgtctgcagg atattgttga tgacactgtt
     1561 tttaaagcct caacgacctt tacaggagaa acagtcttag ctggcagtga ctggctaaat
     1621 caggagctgt cctatgcttc tgcggtgacg actggctttg attcgattga tattatccta
     1681 aaagaggttc ataagggctt tggcatggat cagctgtgtc agcacctagg cattttaccg
     1741 gaaaagacca ttgcctttgg cgataatcta aatgattatc aaatgctgtc ctttgcaggg
     1801 caggctattg ctactgaaaa tgcaaggcct gaaatcaaag cgatttctga tcaggttatt
     1861 ggtcattgta atgactcagc agtgttaact tatttggagg gattggtgta aatgacgcgt
     1921 ataaagcttt tagctctaga tttagatggg actctctata ataccgaaaa aatcgttagt
     1981 gatgagaaca aaaaagctct agcagcagct aaggaaaaag gagttaaggt tgttatcaca
     2041 accggacgtc ctcttaaggc tatcggaaat ttgcttgagg agctggattt gctaggtgaa
     2101 gagaactata gcattacctt taatggcggt ctggttcaac gaaatactgg tcatatttta
     2161 gataaaagcg ctctaagcct tgctgaggtt tatgacattc atcagcagtt ggcagcggtt
     2221 ggcttaccta ctgatgttat cagtgatggt actgtttata gtctatcagg caatgatggc
     2281 agacgctctc agtatcactt ggcaagtccc ttgctgaact ttgttagcct taaatcattt
     2341 gctgagctgc caaaggacat cacatacaat aaaattgtta cggtgacgga tccaaaggtc
     2401 ttggatcagc agcttgcaag gcttccaaag actatctttg aggattttga ggcctttaaa
     2461 tcacgagaca tcatctttga gattatgcct aaggggattc ataaggcatt tggtttggac
     2521 ctgctttgtc agcacttggg cttggaggcc aagcatgtca tggcgatggg agatgaggcc
     2581 aatgacttta gcatgctaca atgggcaggt cttggtgtgg ctatggccaa tgcggttgat
     2641 caggctaagg aagtggcaga tgcagtgact accctaacca atgaccaatc aggtgtggct
     2701 gaggctattt ggaaatatat tttaaatgag gaaggctaat gggattattt gaacgcttat
     2761 ttggaaaaaa ggataagact aaggttgctg agcaagaggc tgccactaca gaggtattgt
     2821 cggaggacat aacgtcaaag gatacgattg agtctgaaaa ggaggcctta tcagatacaa
     2881 atgctcatgc agtggcagct gatgtggtct ctaggaccga tgacactagc aaacaggctg
     2941 agctctcaga cgaggctgct tcagagcaag ctgaagggct tgatccagca gctagaggag
     3001 cttttctttt agaaagagag ccggagctag agttagcagc tactgatgac aagaccttgg
     3061 atcaggcagg tgagagccta agccagcacg aggctatgga ggaggctaag catgataggg
     3121 ctaagtcaga gcatagtaac gagagcgcag acgcatcaac agaagatcag gcagagacaa
     3181 atgctgagta tcaagtagca gctcaagcac ctgctggttc agctgatcag ccagctgagg
     3241 aaggccaaaa gcaagagacc ctatcagctg aatctgatca ggaaaaatac aagcgcagct
     3301 taaagaaaac ccgtacaggc ttttcagcac gcttgaacag cttctttgct aactttagac
     3361 gtgttgacga ggacttcttt gaggacttag aggagctttt gattctctca gatgttggtg
     3421 ttcatgttgc cacaaccttg actgaagaat tgcgctatga ggctaagctt gaaaatgcta
     3481 aaaagccaga ggctctaaag cgtcttatca ttgataagct agtggctatt tatgaggggg
     3541 atggccgcta caatgaagcg attcattatc agcctggctt gaccgttatg ctctttgttg
     3601 gggtgaatgg cgttggtaag acaacatcaa ttggaaagct agcttatcgg tataagcaag
     3661 agggaaaaaa ggttatgctt gttgcagctg ataccttccg agcaggcgcg gttgcccagc
     3721 tggttgaatg gggacgacgg gttgatgtgc cggtcattac aggccctgaa aaagcagatc
     3781 cggcctctgt ggtctttgat ggcgttgaga gggctgttgc tgaaagggca gatattctcc
     3841 tgattgatac cgcaggccgc ctgcaaaata aggacaacct aatggcagag cttgaaaaaa
     3901 taggacgaat cattaagcgt gtcatacctg atgccccaca cgaaaccctg ctagcgctcg
     3961 atgcctcaac ggggcaaaat gctctgagtc aggctaagga gttttcaaaa atcacaccgc
     4021 tcacaggctt gattttaact aagattgacg gtacagctaa ggggggaatt gtcctagcta
     4081 ttcgtcagga attggatatc ccagtgaagc tgattggctt tggtgaggct attgatgata
     4141 tcggtgaatt tcactctgag gactttatga agggactatt agaaggcata ctttaagagg
     4201 aaagcctcag attatcggct gttggccaaa gagaatgagg gggttcgttt agaggcaaat
     4261 gtcaaacagc cttttgaaaa cgcttgacag gacctttagg agatgataaa atgaaaacgt
     4321 tattagatgt gattacttag ggtaagcgtg ctaatgacaa atgaatcaga atattaaagg
     4381 atgttatcac agttttgtga gcagggacct attccagtgt ggccttttag catgctgtgg
     4441 ataggtcatt ttttattgtg aagcaatgag ggactaggac ttttatgatt attaaacgcg
     4501 ttttaaacca taatgcagcg atttcgacca accatcaggg gctagatatt cttttgatgg
     4561 gaaaggggat tgcttttaag aaaagaattg gtgaccatat cgatagtgaa gctatcgaag
     4621 cgtcatttgt tttaaaaaat agtgacaata tgaaccgttt tactgaatta tttattgctg
     4681 ttccgcaaga ggtggttgct tgctcagaga ggcttattaa tctagggaaa attaagctgg
     4741 gtaaaaattt agatgaaata ctctatatca atttgacaga ccatattcat tcagctattg
     4801 aaagacataa gcaggggatg atcattagtg atcccttgcg ctgggagatt agacggtatt
     4861 atcctgatga atatgcgatt ggcgttaagg ccttagaggt cattgccagt gagctaggag
     4921 tcgctctggc tgtagatgaa gcttcgttta ttgcgatgca ctttgtcaac gcgagccttg
     4981 ataatccttt caaggagcct catcgaatga cagaaattgt gtcttacatt gaacagaagg
     5041 tcaaggctga ttttaagaca gagcttgatg aagtctctat tgattattat cgctttatca
     5101 ctcatgtgaa gctatttgct cagcgcgtgt tatcaggcat ggcttatgat gatgacgaga
     5161 ctgatttgct gctgatggtt aaggataaat acccagagga atatcactgt gttaggcaaa
     5221 ttagccatca catgaaaaaa gcataccatt atcagcttag ctctagtgag cttttgtatt
     5281 taacggttca tatcaaacgt ttagtcaaaa atgtgaagga gtaatgaaat gacttatcaa
     5341 gaaacagcca aggccatttt tgaagcagtt ggtggtgagc agaatattca agaggtaacc
     5401 cactgcatca cgcggttacg cttggttttg aaagatgata aacaagtggt agatcaaaaa
     5461 atcaaactta ttcctaatgt gattggagtc atgcgccaaa acggtcagta tcaaattatt
     5521 ttaggaaacg atgttaacaa ttattataag gcatttatga ccctaggaca gtttcatgaa
     5581 actgatatga gctctagcgc tggtcaaaag cagtctatga ttgaagggtt gattgaaacg
     5641 atagctagtg tgattactcc actgatacct gccttactgg gaggcggtat gttaaaggtg
     5701 gttgggatct tggtgcctat gcttggtcta gcaggtacgg actctcaaac agttgctttt
     5761 attaattttt ttggagatgc tgcttattat tttatgccaa tcatgattgc atattcagct
     5821 gcggcacgct ttaaggtcac acctgtatta gcagcaactg ttgcagggat tttactacac
     5881 ccagcttttg ttacgatggt agctacaggt aaacctatgg ctttgtttgg agcgccggtg
     5941 acacctgcta gctatggtgc gtcagttatt ccgattttaa ttatggttta cctgatgcaa
     6001 tacattgagc gagaggttaa ccgttttgta ccgagtgtga tgaagagctt cctgcagccg
     6061 accttgatta tttttatttc aggctttcta gccttagttg ttattggacc tctgggtgtt
     6121 attataggac agggcttgtc taatagcctg ctagcgattt accatattgc tccttggctg
     6181 gctcttgcta ttttaggtgc aattatgccg cttgttgtta tgacgggtat gcattgggcc
     6241 tttgctccta tttttctggc ggcctctgta gcaactccag atgttttaat cctcccagca
     6301 atgctagcct ctaacctagc tcagggatca gcagcggtgg ctgtagcatg tcaatcaaag
     6361 caaaagcaaa cccgtcaggt tgccttagca gcaggcttat cagctttatt ggcaggaatt
     6421 acagagcctg ctctttatgg cattactcta aagtttaaaa agccgctcta tgctgcaatg
     6481 atttctggtg gccttgtggg cgcctatatt ggctttgtta atatagcctc ttatactttt
     6541 gtggtgccat cactaattgg attgccacaa tacattagcc cgactagctc tgctaatttt
     6601 accaatgcct taattgcagc gggcttaaca attgctctaa cctttacatt aacctggttt
     6661 tttggcattg atgaggaggt tgaccaggag gggtcagctg actcggatag cacgccagta
     6721 aaaagtggct tatcagcaaa gcaatctatt tatgctccga tggttggcac agtgcttcca
     6781 ttatcagagg tgccagatga aaccttttcg tctaagcttt taggagaggg gctggctatt
     6841 ttacctaatg aggaatatgt ctatgcccca tttgatggcg aggttatcac cctttttcca
     6901 acaaagcatg ctattgcttt aaagaacgcc aagggagttg acgtcttaat tcatgttggt
     6961 attgatacgg ttgagctaaa aggacagggc tttgagcagc tggttaaggc tggtgatact
     7021 gttaagcagg ggcagccgct gctacgtata gatcttgaat tgattggctc taagggctat
     7081 tctttagtga ctccatttgt ggtgaccaat agctctgagc agctcgaaat cattgttaat
     7141 gacaacaagg agcatatcac tcagcatgat gttgctctcg ttattctcta aagagatgaa
     7201 ttgaaggagg agataatatg gtttgttttc caaaggattt cttgtgggga ggggcagttg
     7261 ctgccaatca ggttgaggga gcttatttaa cagatggcaa aggcttgtcg gttcaggatg
     7321 ttttaccaga agggggctta ggagactata cagctgagcc aacagcagct aatttgaagc
     7381 tagaggccat cgatttttat caccgctaca aggaggacgt ggcgctcttt gcagaaatgg
     7441 gctttaaggt tttccggaca tcaattgctt ggtctcgtat ttttcctcag ggcgatgaga
     7501 cagagcctaa cgaagcaggg ctacaatttt atgacgattt gtttgatgag ctgatagcac
     7561 atggcataga gcctttagtg accctatctc actacgaaac cccactgcat ctagctaagg
     7621 tctataatgg ctggactgac cgtcgtatgg ttggcttctt tgaacgtttt gcgacaactg
     7681 tcatgcagcg ctacaagaac aaggttaagt attggttaac cttcaatgag gttaattcaa
     7741 tcctgcatat gccttttacc agtggtgcta tcatgacacc aaaggaaaag ctgactccgc
     7801 aggagcttta tcaagcgatt caccatgaat tagtagcgtc tgctagtgtg acaaggcttg
     7861 ctagattgat taaccctgct tttaaaatag gctgtatgat tttggctatg ccagcctatc
     7921 caatgacctc tgatccgagg gatattttag ctgcgaagca gtttgagcaa cgtaatctcc
     7981 tgttctcaga tattcaggtc agaggaaaat acccttccta tgccaaatcc ttttttaagg
     8041 agcagcacat tgacattcaa tttgaaccgg gcgacagtga gcttttggcg cagcatacgg
     8101 ttgacttttt atcctttagc tattacatga gtgtgactca gtctcatcac ccggatcatt
     8161 atcaacgagg ggagggcaat attttaggtg gcttggttaa tcctcatctg ccctcttcgg
     8221 aatggggctg gcaaattgat ccaattggcc ttcgcataac cttgaatgat tactatgata
     8281 ggtaccaaat tcctctcttt attgtagaaa atgggcttgg cgccaaagat aagctagtac
     8341 agacaaagga tggtcactgg acagttcagg acgattatcg gattgattac atgaggcagc
     8401 atttattgca ggttgctaag gctattgagg acggtgttga cattatgggc tatacctcct
     8461 ggggctgtat tgattgtgtt tctatgtcga ctgctcagct aagtaagcgt tatggcttta
     8521 tttatgtcga ccgacatgat gatggcagtg gtcatttgac acgctacaag aaaaaatcct
     8581 ttgcttggta tcaaagggtc attgagacca atgggcgtag cctgtctgag gagagctaga
     8641 aagtagcctc aaaggcttta ccaacaatag caaagccgta tagcacacgt cttttaaaag
     8701 gctgatgcta tacggctttt agccatttca tttaaatgga acgaactcaa ttacgtcttt
     8761 gtactgtccc ctaacaaaaa gcctccatag acctgtgtca taggtgtgga ggcttaatgc
     8821 ttgttaaaat accctataga cataagggtt atcaggctct ggggcttggt gtgcttcctc
     8881 gatttgaagg acaggaagct gctgctctag ggtcttgtca tattccatgt gcagctggcc
     8941 cttgacggtc agccaagtgt tattggcata gctttcttga ttaccagtgg tcagaagccc
     9001 atacacaccg gaatcagcga tacaatggat aatcccaaat ctaaagagga attgatagct
     9061 gtcatgtcct ggctcattat agacaaagcc agtgtactga atcgtacgat caacgaattc
     9121 gtctgggtaa aggtagatta attccattac ctccatataa ttgtcagtgg taatggtgat
     9181 ggctgatttg ccttggtatt ttttcagttc attgagcatt tccttttgat aggcggattt
     9241 ggtaaagtac aggctggtgt ctggctttag gtattgaata gtagtaccat catcactgac
     9301 ccctgttttt gaagcgcctg cggctaatgg aaaggtatag cccttggcgg caacggtcgt
     9361 cgaatccaag ctgactgtag gtactaacaa gccaaccaaa acaggaaaga ccaggataag
     9421 gggactggtc agctgagcga ccttaccttt taaatgactg tgtagcttga tgtttttagt
     9481 ccaagtgtat agctgcacca atgcaaggat aaaggataga accatagaaa tataggctaa
     9541 gtaagcgtaa cgaatattga tatattgatt tagcttgcca gatagctcta gatacatggt
     9601 caactcaaaa tagcctgcta aaattaaaaa gcgaatcatc acagcacccc cacaagtaag
     9661 caatatatgg taatcatcac agctgataca ctgataaatt gaacaataaa ggctccctta
     9721 aaggaattga gcatcatcat gaggtttttg atgtcaacca tagggccgat taagagaaag
     9781 gctaaaacag gagcaactcc aaaggttgac aataacgaag ctccaataaa ggcgtcagcc
     9841 tcactgcaaa gagataagat aaaggctaag agcatcatga ctaagatggc tgtcaaaggg
     9901 ctatgtccga tcgctgtcag cacctttgtt ggcagataaa tctgcatggc tgaagcaatc
     9961 agggtcccaa agactagata ccttcctgta tcaaaaaatt cgtcaatagc gtgagccagt
    10021 gccaagtaaa gccgttttgg caggctttcg tgactgtaag tatgacaatg caccggctgg
    10081 gttgattcct tgagaatgtt ctcatcaaca atgaaggcta gcatgatgcc aaggctgaca
    10141 gccactaaaa tggcgcctaa aagccttagc atgagaaagc gcagcgaatt cccaaaggca
    10201 gagtaggtag caaataaaac aatcggatta ataattggag cggttgctaa aaagggaaca
    10261 gcagtgtagc taggcacctt cttttctaaa aaacgattaa taataggaat gataccacat
    10321 tcacaggaag gaaaaacaaa gccaataaag gtaccaaata aaattcttag ccacttattt
    10381 tgagggaggt atctttgaac taaatcaggc gtgacgaaaa cctcaataca gccagataaa
    10441 atagtcccta aaaatacaaa aggcagggct tcaatgataa tggatagaaa aatcgcaaac
    10501 cattgaagca cgctgggtgg cagatttgaa aaaagcgaca ttcaccgtat cctttctata
    10561 tgttaacgac gccaataagg gctagtcctg cttagctgtc ttgacttgtg gctttggttt
    10621 ttcagtgact agctttccat cttggttaag ctctaaaggc ttatcaaaat ctgggataga
    10681 cgcaaagcct gccatcatct tttcgagctg gtcatttttc ttatgagtaa ttgccatagg
    10741 tataccttct ttcaatcaat atagctctat tatacaatca tttgacggta aagccaaagc
    10801 taaaacatct ttttatcttc tgattgattt taggcttcag gccgtcaagc agtgtgtcat
    10861 tagattgact gacaaatatg atataatgtg gctgatggga gctatgaaat gacaaaacga
    10921 gtattattag tagatgatga ggagcctatc ttaaggctac tggattatca cttggccaag
    10981 gagggctttg tgacagagat ggtaacagat ggccgtactg ccttggcatt agctgaaaga
    11041 gaaccttatg attttattgt gttagatatt atgctgccgc aattagacgg tatcgaggtc
    11101 tgcaaaaggc ttcgtgctaa gggaagcaaa accccaatta tgatggtttc tgctaaaagt
    11161 gatgaatttg acaaggtttt ggctttggag ctgggggcag atgattatgt gaccaagccc
    11221 tttagtccta gagaattatt agcgcgtgtc aaggctattt taaggcgtac tgaagcagag
    11281 atttctggtg atggtgaaga gcgtcgtgag cctttttata cgatgagtca attgcgtctg
    11341 tacccagagc gacatgaggt ctataaggac aaggagctat tgccgttaac cccaaaggaa
    11401 tatgagctac tgctctatct catgaagcac cctaatatga ccctgacgcg tgagcggcta
    11461 ttagagcgta tctggggtta tgactttggc caagaaacac gtctggtaga cgttcatatt
    11521 ggcaagctca gagaaaaaat cgaggacaat cctaaggcgc ctcagtatat tcaaaccatt
    11581 cgcggctatg gctacaaatt taaggagcta aagaatgata ggacatctta ggcgtttgag
    11641 catgctgcta gggctttgct tgctggctgc tcttggtctg atttggcaag ggccgcatca
    11701 ggtgctgact ctagtagtgc tgtgtactgg tctcgtagct agcttttatg tcttgagcat
    11761 gctatttaga tgggagcgtg aattcagagc cttgcaccac catcttttga cagctagtga
    11821 ccattttctc ctagtggggc aggctgattt aagtgcttat gctaagcagc tgacagagct
    11881 aaaaagtgac ctattacaaa aggaagcaag gctaaaagcc ttatcaaaaa atgtggaggc
    11941 tgtaacctct catctcacga tgggcatgct tttagtctcc aatcaaaggg agctgttgct
    12001 gaccagcaaa tccttaccgg cttattttcc agaggctaag ccaccttttg tggtcttgga
    12061 ggatcttaaa cgaatggatc tgatagcctt agttaatcaa gtctttgacc aaaagcagac
    12121 attaaagaag gaattaacag gcctacatga tggtgatttg atcttggagg ttacccttgt
    12181 gcctatcttt aaccagtcgc atgttgtcaa ggagatttta gtgctcttat atgatctgac
    12241 ggccattcgt cattatgaga ggctaaattt ggagtttatt gctaatgctt ctcacgaatt
    12301 aagaacaccg gttacatcga tcaagggctt tgctgaaacg attaaggaaa tgcctgacga
    12361 tgaaacaagc ctaaaagaag actttttaga cattatctac aatgaaagct tgcgtctaga
    12421 acgtattgtt gagcacctgc tgaccttatc caaggctaac aagacaccac ttgacctgac
    12481 agagtttcag ctcaggaact tcctgctgta tacaggtcag agcatgaggc cacagctaga
    12541 gcaaaagcag cttgagctaa gctatgcatt ggaggattcg attgttgtga catctgatca
    12601 atacctctta tcgcagatca tgttaaatct cttatcaaat gcgatacagt atacagacaa
    12661 tgggggcaga attcagctat ccagtcaaag ggttgctggt ggtgttgcca ttacagttgc
    12721 agatactggg attggcatta gccaaattga gctagatcgt atttttgagc gcttttatcg
    12781 tgttaacaag ggacgtagca ggcaaagtgg tggaacaggc ctaggcctag ccattgtaaa
    12841 ggagctgagt cagcttcttg gcggtcagat aacagtcaca agtcagctag gagagggcag
    12901 ccaatttacc ttattcttac cagaagctat caacaagtaa acagtcacta ccagctactt
    12961 aaggccagcc ttggtagtgg ctgttttagg ttttacaaaa tctttacatt aatcagggat
    13021 aaacctttac aaagacctga taagctatag gtgtagcaag cctacaacac aatatcataa
    13081 aagataaggg tgattcttat gacaatcaaa aaaatgctga tcatggcagc tattggctta
    13141 tcaggcttag gtcttgcagc ctgtggcaat aacagtgctg atgctggaaa agcagcagac
    13201 aggattgacc ttgtttctcg agaaaatggc tcaggtactc gtggagcctt taccgaaatg
    13261 acaggcattc taaaaaagga cggtgacaaa gagattgacc aaacagcaaa aacagctatt
    13321 atccaaaata gcacagaagg ggtcatctcc tctgttaagg gaaatagtcg tgccattggc
    13381 tacatctcgc tagggtcctt aaatagcgac gttgcagccc taaaggtaaa tggcgtaaag
    13441 gctagtcgtg agactatttt agaggggaaa taccctctgc agcgtccctt taatattgta
    13501 tggtcctcag acctatcagg agttggtaag gattttatca cctttattga ctcaaagcag
    13561 gggcaggaga ttgttagaga caatcgattg atcgaagcaa aaacagacgc gccagcctat
    13621 agcagtaagg gcttatcagg caagctgtca attgtaggct caacctcagt ttcacccttg
    13681 atggaaaaat tagcagaagc atacaagaaa gaaaatccag ccattagcat tgatattacc
    13741 tcaaatggct catcagcagg tatcaccgcc gtcaaggaaa aaacagcaga catcggtatg
    13801 gtttctcgtg acctaacaac tgaggagagc aagggcttaa ttgatgatgc gattgccctt
    13861 gatggtatcg tagtgattgt tcacaaggac aataaggtaa gtaatattgg catagatgtg
    13921 ctggctgatg tctttagcgg caagctaaca agctgggaca aagtcaaata aagaacgatt
    13981 agaaggaagg caaagaagag gtgttttgtt cttgctttcc tttcttagaa aggatcatca
    14041 gtgaataaac aagcctttaa agaggatttt tttaaagtta tcttctttct cagtgcagcg
    14101 atggcaatta ttgctatttg tttaatctgt atctttattt ttagtaatgg ccttcccttt
    14161 attgctaagt atggtatgag agcctttttg ctaggaaatg attggtcacc gtcaaatcag
    14221 ccggcaagct atggtatttt gccgatgatt gcagggtctt ttgtcatcac acttggtgca
    14281 atggtgattg gtgtgccaac aggtatattg acctcagttt ttatggttta ctattgtcct
    14341 aaagcatgct atggcttttt aaagtcagct gttaatctga tggcagccat tccgtctatc
    14401 gtttatggct tttttggtct tcaagtgcta gtgccttgga ttaggagctt tgctggtaat
    14461 ggcatgagtg tgctgactgc ctccttgctc ttaggaatca tgattttgcc aacgcttatc
    14521 agtctttcag agtctgctat cagagctgtt ccaaaggctt attattcagc tagtcttgca
    14581 ctgggagcca gtcatgaaag gagtattttt cgagtgatcc tgccagcagc caaatccggc
    14641 cttttttccg ctcttatttt aggatttggt cgtgccattg gtgagacgat ggcagttatt
    14701 ttggtagcag gaaaccagcc tgtgctgcca tcaggattat ttgagggcac aagaaccatg
    14761 acgacaaata ttgtcctaga gatggcatat gcttctggtc agcatagaga ggccttgatt
    14821 gcaacatcgg ctgtcctctt tggctttatt ctcatcatta atgcttgctt tgcttatgtg
    14881 aaaggaaaat cagctcatga ctaactattt actaaaagcc ctggtctatc ttttgtcgct
    14941 attgaccttt ggctccttat ttttgattat tgcctttatg ctgataaaag gcttgcctag
    15001 tctgtcgtta tccttatttt catggaccta tacctctgac aatgtttctc taatgccgtc
    15061 gattatctca actgttagtc tagttttagg caccttagtg ctagccttgc ccattggtgt
    15121 ctttgctggc ttctatcttg tggaatacgc taagcaggac tcactatggg taagggcaat
    15181 acgtcttgca gctgatacgc tatcagggat tccttcgatt gtttttggtc tttttggcat
    15241 gctgttcttt gtggtttttt tcggcctgca atattctctt ttatcaggta ttctgacgtc
    15301 tgtaatcatg gtgttgccag ttatcattcg atcaacagaa gaagcgctcc tctctgttag
    15361 tgatcacttg cgtcaggcta gccttggctt aggagcaggt aagctaagga cgatttttaa
    15421 aatagtgctg ccggctgcaa tgcctggtat tctagccggg gtaatcctag cgattggacg
    15481 tgttgtgggt gagacagcag ccctgatgta taccctaggc acctctacca atacgccaac
    15541 cagcctcatg tcatcaggac gctcactagc tcttcacatg tacatgctgt ctagcgaagg
    15601 gctacatgtc aaggaagctt atgcaacggg tgttatctta ctcataactg tcttgctgat
    15661 caatgcccta tcaagcttat tatcacgccg attagtgaaa ggagtcgtct aaaatgggag
    15721 ctttttcaac caagcagctt aatgtctttt atggagcatt tcaggcctta aaggatatct
    15781 ccattgacat accagaaaat cagatcacag ccctgatagg tccctctggc tgtggcaaat
    15841 caaccttttt aaaaacccta aatcgcatga atgacttgat tccttcctgt cgtatcgaag
    15901 gagaggttct cttagacaat caagacatct atgctaaagc aataaacctc aacagtctgc
    15961 gtaagcgtgt tggtatggtc tttcagcagc ccaacccatt tgccatgtct atttatgata
    16021 atgtggctta tggtcctagg acacatggcc ttaaggacaa gaaaactcta gatcagctgg
    16081 tagagcagtc cttgagagga gcagccattt gggacgaggt caaagacagc ttaaaaaaga
    16141 gtgccatgtc cctatcaggt ggacagcagc agcggctttg cattgcaaga gcgcttgctg
    16201 tagcacctga tgtgttgctc atggacgagc ctacctctgc tcttgatccc atttctacct
    16261 taaaaattga ggacttggtt cagcaattaa agcaggatta cacgattatc atcgttaccc
    16321 acaacatgca gcaggcttca cgcatgtcag ataaaacagc ctttttcctc acaggagata
    16381 tttgtgaatt tggcgataca gctgaactat ttacaaagcc aaaggacaag cgtacagagg
    16441 attatatttc cggacgcttc ggataagaaa aggactaggc gatgaaagag caattggaat
    16501 gagggctaaa tctctcctca attggtgttt tgatgatgtc agatcagtat cctattagcg
    16561 tggaagcttc tctcttactt cctgtagagt gaagcttttt tgctttcttt gataagcacg
    16621 atctagctat tttcagacaa aggttactgg tattagaaat atatatatat atatattagt
    16681 aaactataat cttattaata ttatataata actacataaa aaaacaaata ggagtcatat
    16741 catgaaaaaa ttactattaa ctagtgctgc agcgctagcc ttagcaacag tagcagttag
    16801 cacaacaaaa gtagaggcgt tttctcgtgg gcatgttata gagcatacga ttaacgacac
    16861 caagtcgctt agtgcagcgc gctgggggtc aagactgcaa atccttaatc tgttaacacg
    16921 atttaagcat aaactaggag aggatggctt taggtcttat aacagacaat tcagagctag
    16981 ggtaggtgca gcaaaatcag taagtgaaat tgatgaactt tataataagt ttgaaaagga
    17041 gttggaagag ttagaagatc tcacttaatt ttgactaacc actaagtagc taaaagacga
    17101 tttccgtttg gagatcgttt tttcttagcc tttagaagta tctgaaaaga taagttttgt
    17161 tttcttgaca cttatttgtc ataaagcttt tatcttgttc tatccctctt tctttgtgct
    17221 ataataagaa ctgttatgga aaatatgaat catcaaaaca tttcagaagc gttgggggtc
    17281 accccaaaac agattagtca agtgcttacc cttaccgctg agggtaatac cattcccttt
    17341 attgcgcgct atcgtaagga agctacaggt aaccttgatg aagtggtgat caaggccatt
    17401 attgatatgg ataagtccct cacacagctt agggagcgta aagacaccat tcttgctaaa
    17461 atcgaaggac aagggaaact aacagctgcc cttaaggaag ctatagaagc agctgataaa
    17521 ttggctgacc tagaggagct ttatttgcct tacaaggaaa agcggcgtac caaggcaacc
    17581 attgctcgag aagccggctt atctggacta gctagactga tccttcaaaa tgcacaagac
    17641 ctagaaacta aggcagaggc ctttatcaca gaaggttttt cggatccaca ggcagccctt
    17701 gctggagctg ttgatatttt ggtcgaagcc atgtcagagg atagcaggct aaggtcctgg
    17761 acctataatg agatttggaa gtatagccgt ataacctcta gcctaaagga agccagctta
    17821 gatgacaagc aggtctttca gatttactat gcgttttctg agacggtatc taacatgcag
    17881 ggctacagga ccctagctct caatcgtggg gaaaagctag gcgtattaaa ggtatccttt
    17941 gagcatcata tagacaaaat gctgcgcttt ttcagccttc gctttaagga gcacaatgct
    18001 tatattgatg atgttattaa ccaaacaatc aagaaaaaaa ttgttcctgc tatggaacga
    18061 cgtatccgca cagaattaac tgaaatggct gaggacggtg ctatcaagct cttttcggaa
    18121 aatttgcgtc atcttttgct aatttcacca ctaaagggaa aaatggtgct gggctttgac
    18181 ccggccttta ggacaggggc caaattagcg gtgattgatc cgactggaaa gctgttaact
    18241 actcaggtta tctatccggt ggcaccagct aatcaagcta agattcaagc agcaagagta
    18301 gctctagctc agctcatcac tgactatcag attgatatta ttgccattgg taatggcaca
    18361 gccagtcgtg agagtgaagc ctttgttgca gaggtgctaa aggattttcc agaaacctct
    18421 tatgtcattg ttaatgaaag cggagcttcg gtttattcgg cctcagagct agcccgccat
    18481 gaatttccag agctgacggt tgaaaagcgc tcagccatct ctattgcgcg tcgcttgcaa
    18541 gacccgctag cagagctggt caaaattgac ccaaaagcaa tcggtgtcgg acaataccag
    18601 catgatgtta gtcagaaaaa gctatctgag catctggatt ttgtcgttga taccgttgtt
    18661 aatcaggttg gggttaacat caatacagct agtccagccc tactggctca tgtttcaggg
    18721 ctaaataaaa ccatttctga gaatatcgtc aggtatcgtg aagaaaatgg agagatcacc
    18781 tcacgtgctg agatcaaaaa ggtccctaga ctaggcgcaa aggcctttga gcaggcagca
    18841 ggcttcttgc gtattcccaa tgctaagaat atattagaca atacaggcgt tcacccagaa
    18901 gcctatccgg ctgtcaaaaa gctctttcaa ttacttgcga ttaaagactt agatgagcct
    18961 gcaagggcca aattacaggc ggttaatctt gaggaaatgg cagagcaatt gacgcttggt
    19021 caagaaacgc tcaaggatat cattgctgat ttgctgaagc caggaagaga cttgcgtgat
    19081 gactttgaag ctcctgttct tcgaaaggac attttgagtg taaaggatct ggctgttggt
    19141 caaaggctag agggaactgt tagaaatgtg gttgacttcg gtgcttttgt tgatattggt
    19201 gtacatgagg acggtttgat tcacatttca gagatgagtg aggcctttgt caatcaccca
    19261 agtcaggtcg tttctgtcgg agatttagtc actgtttggg tttctaaggt tgacttagac
    19321 cgccacaagg tcaacctaag cttagtgccg cctcgtgagt ctgactgatt atgttagaga
    19381 ggtctcgcta gctgattttg gaaagccctt taagcatcag gcttcttgga acagacgact
    19441 aagaacaaca ggcggacgtt tttttccaaa ggatggtcat ctggatttca atcccaaaat
    19501 cttagaggag catggggaga ctgtctttag acagatcgtt aggcatgagc tttgtcatta
    19561 tcacctctat tttgaggggc tgggctttcg gcataaggat caagccttta aggagcttct
    19621 agaccaagta gacggtctga gatacgctcc aaaattacag tcacatcaag ctaattacct
    19681 ctacatctgt caagattgcg gccaagctta tgaccgaaaa cgtcctatca atctggcggt
    19741 atttgcctgc ggcaggtgtc atggcaggct cattgaaaaa aatcagtcgt aaggctgatt
    19801 ttattttgct aaaaaaggaa taaactagta tcatagaata aggaggcgag gagacatgga
    19861 atctaaattt tataagcaac gaaagcataa gctagtggct ggagttatct ctggtttagc
    19921 tgataaatac ggctgggatt tgcccctagc tcgtgtgctt gccgccttat tgatctattt
    19981 tactcgcttt ggggttgtta tttatattct tttagccatc ttcctaccat ataaagagga
    20041 cctacttgaa gaacgttacg ggagaggacc aagacgtcgc aaggatgctg atgtcctaaa
    20101 tgatgaagat gaaggctggt tttggtaaga ccacagcgag cgactattaa aagcttgaca
    20161 ggaattttaa tagtgcctct agcgtgatta tcagaaataa agctggctgt aggcctttat
    20221 ctgatgagat agggcctttt gttgtttgtc cgctttaggc tagtgcctgc tttaagtgag
    20281 cctgaggcag ctgttgcagg attctttttt agtatgatca agcactttga aagcttcttt
    20341 gaaaaataag tatttgtaag ggcttagata gtgatttatg atataatatt aaaaaaggag
    20401 aaattatgac agttaccgtt aagatgttag tcacaaaggt caagcttgac gttgtctatg
    20461 caactgatga cttgctagaa aaggagataa cgacctcaga tatttcgcgt ccgggtcttg
    20521 agatgaccgg ctattttgat tactatgccc cagagcggct tcagctgttt ggcatgaaag
    20581 aatggtccta cctcactcag atgacctcac acaatcgcta ctcagtctta aaggaaatgt
    20641 ttaaaaaaga cacgccagct gtgattgtat ctaggggcct agctatccca gaggagatgg
    20701 ttcaggcagc gcaggaggaa ggtattgctc tgtttagcag ccgcgtatct accagccgct
    20761 tagctggtga gatgtcttat tttcttgatg cttccttagc agagcgaaca agtgtgcatg
    20821 gggtgctgat ggatatttac ggtatggggg tgctgatcca aggtgattca ggtattggta
    20881 aaagtgagac aggcttagag ttggtcaagc gtggccatcg cttggtggca gacgaccgag
    20941 tagatgtctt tgctaaagat gaggagacgc tatgggggga gccagcagag attttacgtc
    21001 atctccttga gattcgtggt gttggcatta ttgatgtcat gtcgctgtac ggtgctagtg
    21061 ctgtcaagga ttcctcacag gtgcagttgg ctatttattt ggagaatttt gaggctggca
    21121 aggtctttga ccgcttgggc aatggcaatg aagagattac cttttctggt gtcagtattc
    21181 caaggattcg cattcctgtc aaaacaggtc gaaatgtgtc agtggttatt gaggctgctg
    21241 ccatgaacca tcgtgcgaaa gagatgggct ttgatgctac caaaaccttt gaggagcgcc
    21301 ttacacgttt aatcagcaaa aatgaggagg gcaaatgatc aatccaatag cctttaagct
    21361 tggtcctctt agtcttcact ggtatgcggt ttgtatcttg gtgggattac ttttagcggt
    21421 ttatttggca gccaaagaag ccccgcgaaa aaaaatgacc agtgatgata ttattgattt
    21481 tattctgatt gcctttcctt tggcaattat tggagcaaga atctattatg tagcctttga
    21541 atggtcctat tattctcagc atttgagtga tatctttgct atttggaatg gtgggattgc
    21601 catctatggc ggcttgataa caggtaccat tgttctcttt gtttattgct actataaggt
    21661 gctgaatcct atccatttct tagatattgc agcgcctagt gtcatgcttg ctcaggccat
    21721 cggcagatgg ggaaatttct ttaaccaaga ggcctatggc agggctgtca gccagctcaa
    21781 ttacctgcct agttttattc gccagcagat gtttatagat ggcagctatc gtgttcccac
    21841 ctttttatat gagtccatgt ggaacctgat tggctttgtc attatcatgg tgtggcggcg
    21901 taagcccagg tcattagtag atggggatat tatctcattt tacctgattt ggtatggctg
    21961 tggtcgattg gtgattgagg gcatgcgaac ggacagcctg atgcttttag gaattcgtgt
    22021 ttctcaatac atgtcggtgc tgctcattat cattgcgatt gtttttatct ttaaaaggca
    22081 tcgacaaaag ggaatttctt attatcaaga atagggatag aaagaggaga cgtttatgaa
    22141 tttagtgggc atttcattgc tgataatcgc attagccttt gttgctctgg ttattttttt
    22201 gattgtggtg ttaaaaaagg tgtcagaggc agttgatgag gctaaaaaaa ccattaccgt
    22261 tttaacgagt gatgtcaatg ttacccttta tcaaaccaat gaaatattag ctaaggctaa
    22321 tgtgctggta gatgatgtga atggtaagat gacaacaata gatcctctct ttgttgctat
    22381 tgcagatttg tcagaaagtg tttctgattt gaatgtgcag gccagacacc ttggacgtcg
    22441 ggcgacaaat gccacaagca atgctgcaaa ggtgggtaaa gtagctcttg tcggcaaggt
    22501 cgcttctaaa ttatttggta aaaaggagaa aaggtcatga gtaatttttt taaaacgttg
    22561 gtgattggtg tagcttcagg agcagctacc gcttatttct tgtcaactga aaaaggaaag
    22621 gtcttgaagg ctcgcgcaca aagggcctat gaagcctatc gtcaaaatcc tgaggaatat
    22681 catcaaatgg ctaaagaaaa aggaagtgag tacagtcagc tggctcgcca tacctttaat
    22741 gatttaaaaa ccaggtttga atcaggggat atgaccactg atcaggtgtt tgattttatc
    22801 aaggaaaaga ccagccaatt tgttcatcag gcaaaggaag ctgcttcaga gcatgacaag
    22861 gctgatgatg tgattattga tctggatgaa gaggatatta ttatcaacta tcctgaagat
    22921 gattcagaaa aagaagcagc tagcaataag tctgaagaat aataaggcaa aaataagggc
    22981 tctctcagct atggagggcc ttttgtgatg tgggctactc gtttattcaa gaaaataggc
    23041 aataagagta atgaaaaaag agcttagcga agccaagctc taactgttta tgacattaat
    23101 aacgtgatgg cctttgaaag aaaggaagtg atggctaggc tgatagcact agcaattaga
    23161 aaggcccaaa ccggtgccaa attcatgaca agaaggacaa atgcaaacaa gacagtgatt
    23221 aaactaaaaa cagcaatacg ggcaaaaaaa ataagttcct tgagcttgct actgtgtcca
    23281 ttgaggtctt gaaactcttg aaatttttgc tgcgagacct gctcttgctt ctgctgcttg
    23341 agctgccgct gctccaatgg tgtaggcata gtcctctcct ttcccgtaag atacccaacc
    23401 attttaccat aaaagctgat ggttgtcatc ttttttttga aggcttctcg tt
//
LOCUS       DARYYD010000032        23392 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.032, whole genome shotgun sequence.
ACCESSION   DARYYD010000032 DARYYD010000000
VERSION     DARYYD010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23392
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.032"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..563)
                     /locus_tag="TV188_001224"
     CDS             complement(<1..563)
                     /locus_tag="TV188_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000600261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1534580.1"
                     /translation="MILGETYRKMREEKGISISSLAGYEISKSQISRFELGETEISIF
                     KLLYLLEKLGITFEEFLLACNNYEPSEFNTLIKAVQNSAYNNKVETLISMIEQENKLF
                     EETNSHYHKLNSIFIQSIISGLDNNHQLTNQDISYLSNYLFSLENWGYYETLILGNCC
                     RSLPPKLLFKYTKEALKKGKLYNSIPR"
     gene            1199..2683
                     /locus_tag="TV188_001225"
     CDS             1199..2683
                     /locus_tag="TV188_001225"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004229889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEL1534581.1"
                     /translation="MPMMYQSTRNAANKVTASQAILSGLADDGGLFTPTSMPVLDLDF
                     EELKTKSYQEVAKLILSAFFDDYTEAELDACISSAYDDKFDTAVIAPLATLKDYHNLE
                     LFHGSTIAFKDMALSILPYLLTTAAKKQGVERKIAILTATSGDTGKAAMAGFVDVPGT
                     DIIVFYPKSGVSRIQELQMITQAGHNTHVVAIEGNFDDAQTEVKRLFNDPDLRERLAA
                     QQIQLSSANSMNIGRLIPQVVYYIYAYAQLVRHQRLEAGETINIVVPTGNFGNLLVAY
                     YAKEIGLPVAKFICASNENNVLTDFFASGRYDKKRPFKVTTSPSMDILVSSNLERLVF
                     YLLGNDAQKTAVLMKSLAETGQYQLADADQSILDLFAAGFATEQETAKEIKTIFESDH
                     YVLDPHTAVASAVYRAYREQSGDSRPTIVASTASPYKFPRVVVEAISGQQVASDFEAL
                     EQLADISGVVVPQAVNGLQEAPIRHSLLVTVADMQQAVEAYLGV"
     gene            2723..4024
                     /locus_tag="TV188_001226"
     CDS             2723..4024
                     /locus_tag="TV188_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEL1534582.1"
                     /translation="MTHNRKKILSLALPSMAENILQMLMGMIDNYLAAQIGLTAVSGI
                     AIANNILTIYQALFIALGAAVSSLIARSVGEQNHSKEIDYMANAILVTGALSVLLGLM
                     SVVGHKSILAFLGAASLVARLGGQYLAIVGGMILSLGLFTSLGAIIRAKGQPSIPMKV
                     SLLTNLLNAVFSALSLYIWGFGVIGIAWSTVASRLIGVVILCHFLPIKEIIKRFANPL
                     DKEIFSLSLPAAGERLMMRAGDVLIVTIIVRFGTEALAGNAIGETLTQFNYMPGLAMS
                     TATVILVANQLGSGKGATIAKTVKETFLLATLMMLVMGLITYLLGPNLLPLFTADAKA
                     QQAGMVVLVFSLLGVPATAGTLVYTAAWQGIGQAKLPFYATTIGMWLVRISLGYFIGV
                     TLNYGVIGVWLATILDNATRWLILAVAFKKQQRQLFSDCHS"
     gene            4404..4712
                     /gene="rpsJ"
                     /locus_tag="TV188_001227"
     CDS             4404..4712
                     /gene="rpsJ"
                     /locus_tag="TV188_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEL1534583.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAEKIVETATRTGATVAGPVPLPT
                     ERSLYTIIRATHNYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            5010..5636
                     /gene="rplC"
                     /locus_tag="TV188_001228"
     CDS             5010..5636
                     /gene="rplC"
                     /locus_tag="TV188_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEL1534584.1"
                     /translation="MTKGILGEKVGMTQIFTESGEFIPVTVIEATPNVVLQVKTVETD
                     GYEAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNIEGLEVGAEITVDIFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVSPNRVFKNKHLAG
                     RMGGNRVTIQNLEIVQVIPEKNVILIKGNVPGAKKSLITIKSAVKAAK"
     gene            5661..6284
                     /gene="rplD"
                     /locus_tag="TV188_001229"
     CDS             5661..6284
                     /gene="rplD"
                     /locus_tag="TV188_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEL1534585.1"
                     /translation="MANVKLFDQTGKEVSTVELNDDIFGIEPNESVVFDVVISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSAKVAEDKFVAVESLSFAAPKTAEFAKVLSALSIDTKVLVLVEEGN
                     EFAALSARNLPNVAVATAATASVLDIVNADKLLVTKEAISTIEEVLA"
     gene            6284..6580
                     /locus_tag="TV188_001230"
     CDS             6284..6580
                     /locus_tag="TV188_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEL1534586.1"
                     /translation="MNLYDVIKKPVITEKSMYALEEGKYTFEVDTRAHKLLIKQAVEA
                     AFDGVKVASVNTVNVKPKAKRVGRYTGFTSKTKKAIITLTADSKAIELFAVEAE"
     gene            6598..7431
                     /gene="rplB"
                     /locus_tag="TV188_001231"
     CDS             6598..7431
                     /gene="rplB"
                     /locus_tag="TV188_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEL1534587.1"
                     /translation="MGIKVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVSLKNKAGRN
                     NNGRITVRHQGGGHKRHYRLIDFKRNKDGVEAVVKTIEYDPNRTANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPDADIKVGNALPLVNIPVGTVVHNIELKPGKGGELVRAAGA
                     SAQVLGQEGKYVLVRLQSGEVRMILGTCRATVGTVGNEQQSLVNIGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSNKLLVRRRNE
                     K"
     gene            7543..7821
                     /gene="rpsS"
                     /locus_tag="TV188_001232"
     CDS             7543..7821
                     /gene="rpsS"
                     /locus_tag="TV188_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEL1534588.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRR"
     gene            7837..8181
                     /gene="rplV"
                     /locus_tag="TV188_001233"
     CDS             7837..8181
                     /gene="rplV"
                     /locus_tag="TV188_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEL1534589.1"
                     /translation="MAEITSAKAMARTVRVSPRKTRLVLDLIRGKKVADAIAILKFTP
                     NKAARVIEKTLNSAIANAENNFGLEKANLVVSETFANEGPTMKRFRPRAKGSASPINK
                     RTTHVTVVVSEK"
     gene            8194..8847
                     /gene="rpsC"
                     /locus_tag="TV188_001234"
     CDS             8194..8847
                     /gene="rpsC"
                     /locus_tag="TV188_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEL1534590.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFINK
                     ELAEASVSTIEIERAVNKVIVSLHTAKPGMVIGKGGANVDALRAQLNKLTGKQVHINI
                     IEIKQPDLDAHLVGENIARQLEQRVAFRRAQKQAIQRTMRAGAKGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            8851..9264
                     /gene="rplP"
                     /locus_tag="TV188_001235"
     CDS             8851..9264
                     /gene="rplP"
                     /locus_tag="TV188_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEL1534591.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVSFGEYGLQATTSSWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEVAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            9274..9480
                     /locus_tag="TV188_001236"
     CDS             9274..9480
                     /locus_tag="TV188_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEL1534592.1"
                     /translation="MKLEEIKKFVAELRGLSQEELAKKENELKKELFDLRFQAAAGQL
                     DQTARLNEVKKQIARVKTVQSEMK"
     gene            9505..9768
                     /gene="rpsQ"
                     /locus_tag="TV188_001237"
     CDS             9505..9768
                     /gene="rpsQ"
                     /locus_tag="TV188_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEL1534593.1"
                     /translation="MMERNQRKTLVGRVVSDKMDKTITVIVETKRNHPVYGKRINYSK
                     KYKAHDEKNLAKEGDIVRIMETRPLSATKRFRLVEIVEEAVII"
     gene            9793..10161
                     /gene="rplN"
                     /locus_tag="TV188_001238"
     CDS             9793..10161
                     /gene="rplN"
                     /locus_tag="TV188_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEL1534594.1"
                     /translation="MIQQETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRPDGSYIKFDDNAAVIIRDDKTPRGTRIFGPV
                     ARELREGGYMKIVSLAPEVL"
     gene            10245..10550
                     /gene="rplX"
                     /locus_tag="TV188_001239"
     CDS             10245..10550
                     /gene="rplX"
                     /locus_tag="TV188_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEL1534595.1"
                     /translation="MFVKKGDKVRVIAGKDKGVEAVVLKALPKVNKVIVEGVAIIKKH
                     QKPNSENPQGAIVEKEAPIHASNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            10574..11116
                     /gene="rplE"
                     /locus_tag="TV188_001240"
     CDS             10574..11116
                     /gene="rplE"
                     /locus_tag="TV188_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEL1534596.1"
                     /translation="MANRLKEKYTNEVIPALTEKFNYTSVMAVPKVEKIVLNMGVGDA
                     VSNAKNLEKAAAELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKVRGLDIVIVTT
                     ANTDEESRELLKGLGMPFAK"
     gene            11132..11317
                     /locus_tag="TV188_001241"
     CDS             11132..11317
                     /locus_tag="TV188_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HEL1534597.1"
                     /translation="MAKKSMIAKNKRPAKYSTQAYTRCEKCGRPHSVYRKFKLCRVCF
                     RELAYKGQIPGVVKASW"
     gene            11650..12048
                     /gene="rpsH"
                     /locus_tag="TV188_001242"
     CDS             11650..12048
                     /gene="rpsH"
                     /locus_tag="TV188_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEL1534598.1"
                     /translation="MVMTDPIADFLTRIRNANQVKHEVLEVPASNIKKGIAEILKREG
                     FIKNVEVIEDGKQGIIRVFLKYGQNGERVITNLKRVSKPGLRIYSKREDVPKVLNGLG
                     IAIISTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            12370..12906
                     /gene="rplF"
                     /locus_tag="TV188_001243"
     CDS             12370..12906
                     /gene="rplF"
                     /locus_tag="TV188_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEL1534599.1"
                     /translation="MSRIGNKVIIIPAGVEIINNDNVVTVKGPKGELTREFNKNIEIK
                     VEGNEMTLVRPDDSKEMKTIHGTTRANLNNMVVGVSEGFKKELEMKGVGYRAQLQGSK
                     LVLSVGKSHQDEVEAPEGITFTVANPTSISVEGINKEVVGQTAAYIRSLRSPEPYKGK
                     GIRYVGEYVRLKEGKTGK"
     gene            13009..13365
                     /gene="rplR"
                     /locus_tag="TV188_001244"
     CDS             13009..13365
                     /gene="rplR"
                     /locus_tag="TV188_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEL1534600.1"
                     /translation="MISKPDKNKIRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVVVGKLVAERAVAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            13384..13878
                     /gene="rpsE"
                     /locus_tag="TV188_001245"
     CDS             13384..13878
                     /gene="rpsE"
                     /locus_tag="TV188_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEL1534601.1"
                     /translation="MAFKDNAVELEERVVAINRVTKVVKGGRRLRFAALVVVGDGNGH
                     VGFGTGKAQEVPEAIRKAVEAAKKSMIEVPMVGTTIPHEVYTNFGGAKVLLKPAVEGS
                     GVAAGGAVRAVIELAGIADITSKSLGSNTPINIVRATVEGLKQLKRAEEVAALRGISV
                     SDLA"
     gene            13893..14075
                     /gene="rpmD"
                     /locus_tag="TV188_001246"
     CDS             13893..14075
                     /gene="rpmD"
                     /locus_tag="TV188_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002959367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEL1534602.1"
                     /translation="MAQIKITLTKSPIGRKPEQRKTVVALGLGKLNSSVIKEDNAAIR
                     GMVTAISHLVTVEDVK"
     gene            14277..14717
                     /gene="rplO"
                     /locus_tag="TV188_001247"
     CDS             14277..14717
                     /gene="rplO"
                     /locus_tag="TV188_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEL1534603.1"
                     /translation="MKLHELKPAKGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRIPKRGFTNINTKEYALVNLDQLNAFEDGTEVTPVVLKEAGIV
                     RAEKSGVKILGNGELTKKLTVKAAKFSKSAEAAITAKGGSIEVI"
     gene            14734..16038
                     /gene="secY"
                     /locus_tag="TV188_001248"
     CDS             14734..16038
                     /gene="secY"
                     /locus_tag="TV188_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015631723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEL1534604.1"
                     /translation="MFLKILKDALKIKNVRNKIFFTIFIILIFRIGTHITVPGVNAKS
                     LEQLSELPFLNMLNLVSGNAMRNFSVFSMGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYISLVLAFAQSIGITAGFNTLSSVALVKTPDVRTYLLIGALLTTG
                     SVIVTWLGEQITDKGFGNGVSMIIFAGIISSIPNAIATIREDYFVNVKSGDLQSSYIV
                     VGILILAVLAIVFFTTYVQQAEYKIPIQYTKLVQGAPTSSYLPLKVNPAGVIPVIFAS
                     SITTIPSTIIPFFQNGRDIPWLTTLQGIFNYQSPTGMIVYALLIILFSFFYTFVQVNP
                     EKTAENLQKNSSYIPSVRPGRETEEFMSSLLKKLATVGAIFLAFISLVPIAAQQALNL
                     SSSIALGGTSLLILISTGIEGMKQLEGYLLKRKYVGFMNITE"
     gene            16190..16831
                     /locus_tag="TV188_001249"
     CDS             16190..16831
                     /locus_tag="TV188_001249"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEL1534605.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVETFELIHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGDLVPDEVTNGIVKERLAQADIKEKGFLLDGYPRTIEQAHALDETLK
                     ALGLTLDGVINIEVDPASLIDRLSGRIINKKTGETFHKIFNPPVGDYKEEDFYQREDD
                     KPETVKRRLDVNIAQGEPIIKHYRQAGIVRDIDGNKDISEVFADIKKVIENLK"
     gene            16949..17167
                     /gene="infA"
                     /locus_tag="TV188_001250"
     CDS             16949..17167
                     /gene="infA"
                     /locus_tag="TV188_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEL1534606.1"
                     /translation="MAKEDVIEIEGKVVETMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILVGDRVTVEMSPYDLTRGRITYRFK"
     gene            17193..17309
                     /gene="rpmJ"
                     /locus_tag="TV188_001251"
     CDS             17193..17309
                     /gene="rpmJ"
                     /locus_tag="TV188_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEL1534607.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPTNPKHKQRQG"
     gene            17327..17692
                     /gene="rpsM"
                     /locus_tag="TV188_001252"
     CDS             17327..17692
                     /gene="rpsM"
                     /locus_tag="TV188_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEL1534608.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGVSEDIR
                     VKDLTSDQEDAIRREVDTIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            17710..18093
                     /gene="rpsK"
                     /locus_tag="TV188_001253"
     CDS             17710..18093
                     /gene="rpsK"
                     /locus_tag="TV188_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEL1534609.1"
                     /translation="MAKPTRKRRVKKNIESGVAHIHATFNNTIVMITDVHGNALAWSS
                     AGALGFKGSRKSTPFAAQMAAEAAAKSAQEHGLKTVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            18140..19078
                     /locus_tag="TV188_001254"
     CDS             18140..19078
                     /locus_tag="TV188_001254"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEL1534610.1"
                     /translation="MIEFEKPIITKIDENKDYGRFVIEPLERGYGTTLGNSLRRVLLS
                     SLPGAAVTSIRIDGVLHEFDTIPGVREDVMQIILNVKGLAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIELVNPDHYLFTIADGYTLKASMTVAKKRGYVPAEGNKKDDAPVG
                     TLAVDSIYTPVKKVNYQVEPARVGSNDGFDKLTIEIMTNGTIIPEDALGLSARVLIEH
                     LNLFTDLTDVAKATEVMKEAEKVNDEKVLDRTIEELDLSVRSYNCLKRAGINTVFDLT
                     EKSEPEMMKVRNLGRKSLEEVKVKLADLGLGLKNDK"
     gene            19093..19479
                     /gene="rplQ"
                     /locus_tag="TV188_001255"
     CDS             19093..19479
                     /gene="rplQ"
                     /locus_tag="TV188_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEL1534611.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAYVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(19697..19928)
                     /locus_tag="TV188_001256"
                     /pseudo
     CDS             complement(19697..19928)
                     /locus_tag="TV188_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195628.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            20784..22034
                     /locus_tag="TV188_001257"
     CDS             20784..22034
                     /locus_tag="TV188_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534612.1"
                     /translation="MSIDMYLSLSEEQAQSVEAVLARRQTAYQSLQETLIQLISNSPD
                     LSGRTYDSAKAYSSQVLIPLLKGCMLLDEAIITACKRLPSEYRSQVDQIDLKESDLVE
                     RIAQFDHVIGRYMDLISIEYSREEPSYSYISHLRSAEQLHRAVKRRLEEILRRLRHFD
                     TNSVHLFSTIQTLAAAVQIGMRQARTSWHAGSQVFVISEDMAWADTINSKWSKSKGLS
                     YLSDYVYDPDVLSKRAAINHSWIKTGYTMSKNFGKAVSKDYTKASFLSYGKAAKATGW
                     TSMAVDTGITSVREYNKKNSRAYGSEGKALIHASVAQIKSMGPIEGAIIGSKAGPWGA
                     LMGFVTGGINVTWGVVHPESKDNMFLWIQDKMDDVYDSIVQTDLGKGTHHAKESVKGH
                     IGRAIVRTWDFVSQSFGKGVGYDI"
     gene            22024..22899
                     /locus_tag="TV188_001258"
                     /pseudo
     CDS             22024..22899
                     /locus_tag="TV188_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677217.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22920..23213
                     /locus_tag="TV188_001259"
     CDS             22920..23213
                     /locus_tag="TV188_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HEL1534613.1"
                     /translation="MQKELLPLGSVVYLEGATSKLMIVGRGPIFESNGQNVYSDYVGV
                     MYPEGINPEDAIFFNHEDIAKTVFEGFKDEEEQRFLEVYSDWESTLEISKIKL"
BASE COUNT         7227 a         4156 c         5143 g         6866 t
ORIGIN      
        1 ttacgaggaa ttgaattgta taattttcct ttttttagag cttccttagt atacttgaat
       61 aatagtttag gaggtaaaga acgacagcaa tttccaagaa taagggtttc atagtatccc
      121 caattttcta aggaaaataa ataatttgaa agataagaga tatcttgatt agttaattgg
      181 tgattgttat caagtccaga aatgatactt tggataaaaa ttgaatttaa tttatgataa
      241 tgagagtttg tctcttcaaa caatttattt tcttgttcta tcatacttat tagtgtttcg
      301 actttattat tgtatgcaga attttgaaca gcttttatta gtgtattaaa ttcagatggt
      361 tcataattgt tacaggcgag caagaattct tcaaaggtta ttccgagttt ttctagtaaa
      421 tataataact tgaaaataga aatttccgtc tctcctaatt caaatcttga aatttgagat
      481 tttgaaattt catatcctgc taatgaagaa atagaaattc ctttttcttc ccgcattttt
      541 ctataggttt cacctaagat catagattat ctccgtttgt agttaaaaag tggaaagcgt
      601 gacaaatgat gagaaaaagt tacaagttac ttaaattgat tcttgatatt atcattatta
      661 taggtttatg tcaataattt ttgtagattg catgaagtat aatgcctata agtttttagt
      721 actcaatttt atgatttaat atttaaatta agcaatagtc aagtcacctt tcactaagaa
      781 aaatcacttg attattgctt agttttttct aatggaggat ttttagttta gaagctttga
      841 gtttagacct caaaacttag atatggaatt cgaaaggcag tcactgctgt caacattact
      901 ttgggaaagt tcctataaga gacttttcat tagactgaag tagcttcaat agctctaaaa
      961 ctacctagac tcaagtaaca acaagtcctt agaattgatt ttctaagggc ttttttgctg
     1021 cctcaaggta aagacatgtt cagcaacaaa ttgactggct agaccagtcc tttatttatg
     1081 ctgatggctt gagactgctg ggttattagc acagaaaatg gctgtctcca aatcctagaa
     1141 ggcttatgat tggaatatga tataatagtc aaaagaaatg atgaggtgat gtgaagcaat
     1201 gccaatgatg taccaatcaa caagaaatgc agctaataag gtaacagcta gtcaagcgat
     1261 tttaagtggc ctagcagatg atggtggctt gtttactcct acaagcatgc cagtgctgga
     1321 tctagatttt gaggagctaa agaccaagtc ctatcaagag gttgccaagc ttattttatc
     1381 agcctttttt gatgactata ctgaagcaga attagatgct tgtatctctt ctgcctatga
     1441 tgataagttt gatacagcag tgatagcacc tctagctacg ttaaaggatt atcataattt
     1501 ggagctattt catggctcaa ccatcgcatt taaggacatg gctctatcta ttttgcctta
     1561 tctcttgaca actgctgcta aaaagcaagg tgtggagcga aaaattgcga ttttaaccgc
     1621 tacctcaggt gatactggta aggcagcaat ggcaggcttt gttgatgttc cgggaacgga
     1681 tattattgtc ttttatccta agtcaggcgt tagcaggatt caggagctgc agatgatcac
     1741 acaggccggt cacaataccc atgttgtggc gattgaaggc aattttgatg atgctcaaac
     1801 agaggtcaag cgcctgttta atgaccctga tttgcgtgag cggctagcag ctcaacagat
     1861 acagctgtct tcggccaatt cgatgaatat tggtcgtttg attcctcagg ttgtctatta
     1921 tatttatgct tatgcccagt tggtaaggca tcagcgactt gaagctggag agacgattaa
     1981 catagtagtg ccgacaggaa attttggcaa tctactggtt gcctactacg ccaaagaaat
     2041 tggacttcct gttgccaaat tcatctgtgc ttccaatgaa aacaatgtct tgacagattt
     2101 ctttgctagt ggtaggtatg ataaaaagcg tcccttcaag gtgactacta gtccatcaat
     2161 ggatattttg gtgtcttcaa atttagagcg cttggttttt tatttactag gcaatgatgc
     2221 ccaaaagaca gcagtattaa tgaagagctt ggcagaaaca ggtcagtatc agctagctga
     2281 tgcagatcag tctatccttg atttatttgc ggcaggcttt gcaacagagc aagagactgc
     2341 taaagagatc aaaacgatat ttgagtctga tcattatgtg cttgacccac atacagctgt
     2401 agcttcagct gtttatcgtg cttatcggga gcaatcaggt gactctagac cgactattgt
     2461 tgcgtcaact gctagtcctt ataagtttcc gcgggtagtt gtggaagcta ttagtggtca
     2521 gcaggttgcc agtgattttg aggcgcttga gcagttggct gatatatcag gtgtagtcgt
     2581 gccacaagcg gtcaatggct tacaggaggc gcccattcgt catagccttt tagtgacagt
     2641 agcagatatg cagcaggcag tagaggctta tcttggagta taggaggcat aaaggagctc
     2701 cctttcaatt gatatgaata taatgactca caatagaaaa aagatactgt ccttggccct
     2761 tccatcaatg gcagaaaata tattgcaaat gctgatggga atgatagaca attatttggc
     2821 tgctcaaatt ggacttacgg ctgtttcagg cattgcgatt gctaataata ttctgacgat
     2881 ttatcaggcc ctttttatcg cattaggtgc tgcagtctcc agtctcattg ctagaagcgt
     2941 aggagagcaa aaccattcta aagaaatcga ctacatggca aatgctatct tagtaacggg
     3001 ggctctatca gttcttctag gcttgatgtc cgtagtggga cataaaagca tattagcctt
     3061 tctgggagca gctagtctgg tagctagact tggtgggcag tatttagcca ttgtcggtgg
     3121 aatgattctt agtcttggtc ttttcacgag cttaggtgcg attattcgtg ctaagggcca
     3181 gcctagcatt cccatgaagg tcagcctttt aactaatttg ctaaacgctg tattttcagc
     3241 cctttctctt tacatatggg gatttggagt gatagggatt gcttggtcaa ctgttgcatc
     3301 acgtctcatt ggagttgtta ttctatgtca ctttcttcct attaaagaaa ttattaaacg
     3361 ttttgctaat cccttagata aagagatctt tagcctctct cttccagcgg ctggtgagcg
     3421 gctcatgatg cgagctggtg atgtgctgat tgttactatt attgttagat ttggaacaga
     3481 ggccttggca ggcaatgcga ttggagaaac cttaactcaa tttaattata tgccgggact
     3541 tgctatgtca actgcgacag tcattttagt tgccaatcag ttgggcagtg gcaaaggggc
     3601 tacaatagcg aaaactgtaa aagaaacctt tttgttagcc accctgatga tgcttgttat
     3661 gggcttgatc acttatttgc taggccctaa tctactgccc ttatttacag cagatgccaa
     3721 ggctcagcag gctggtatgg ttgtcttagt cttttctctt ttgggggtac cagcaacagc
     3781 cgggaccttg gtttatacag cagcctggca gggtatcgga caagctaagc ttccctttta
     3841 tgcaacaacg attggtatgt ggctggttcg gatttctttg ggctacttta ttggagtaac
     3901 cttaaattat ggagtaatag gtgtttggct tgcgactatt ttggacaatg ctaccagatg
     3961 gctcattctt gcagtggctt ttaagaagca gcaaaggcag cttttttcgg actgtcatag
     4021 ctaaactttg tatttaggtc tcaagacttc tgagtggtga ctttcctttt gggagtcagc
     4081 cactgtcatc agaatgtaaa gtacgcctga ggctctgttt gctaatagct tctcttatct
     4141 gcggaagatc aaagaggatt gctggaacag ctgaggtttg tcttcaatct ggcttgccct
     4201 ttcttagggc aagttttttt gaaaaaatcc cctgaaaggc ttgcaatgcc ttattaattc
     4261 tgctattata ttatggtgct gtaaaaatac agctttagct gtgatacgag aggttgcgac
     4321 acgctcggtt gcattgccac gtgacaggtg tcggttttct cgaggagcta gcctattatc
     4381 gtaaatagac gagaggagaa aagatggcaa acaaaaaaat ccgtatccgc ttgaaagcgt
     4441 acgaacaccg tacacttgat acagcggcag aaaaaatcgt tgaaactgca actcgtacag
     4501 gtgcaacagt agctggacca gttccacttc caactgaacg tagtctttac accattattc
     4561 gtgcgactca caattataaa gattctcgcg aacaatttga aatgcgtaca cacaaacgtc
     4621 ttattgatat tgtgaaccca acgcaaaaga ctgttgatgc acttatgaaa ttggaccttc
     4681 caagtggtgt caacgtagaa atcaagcttt aattgtttga aacatgagtg aggaacgagt
     4741 tcatatctaa ttgaacacag gctaaactct gtgtgaaaaa gagacacagc cgttctaatt
     4801 ttaattagat tacggatgtg gctacctgta ggtgtaaatc ttcctagaaa cagaagtttc
     4861 ttcgtcagat ttcctatttt cactgtgagt ttgacgcctt aagtatcttg ctttgagcat
     4921 aaaaaacgct cgtaaaaaac ttttttgagc ataaaaaacg ctcactaaaa actttttgaa
     4981 atattattaa gaaaaggaat tattttctca tgacaaaagg aatcttaggg gaaaaagtgg
     5041 gaatgactca aatcttcact gaatccggtg aatttatccc tgttactgtc atcgaagcaa
     5101 ctccaaacgt tgtgcttcaa gttaagactg ttgaaacaga cggttacgaa gcaattcaag
     5161 ttggttttga tgataaacgt gaagtattga gcaacaaacc tgccaaaggc catgtagcaa
     5221 aagctaacac agctcctaag cgcttcattc gtgaattcaa aaacattgaa ggcttagaag
     5281 taggtgcaga aatcactgtg gatatcttcg cagctgggga tgttgttgat gtaactggta
     5341 cttcaaaagg taaaggcttc caaggtgtta tcaaacgcca tggtcaatca cgtggtccga
     5401 tggcccatgg ttctcgttac catcgtcgtc caggttctat gggacctgtt tcaccaaacc
     5461 gcgttttcaa aaacaaacat ttggcaggac gcatgggtgg caatcgtgta actattcaaa
     5521 atcttgaaat tgtacaagtt atcccagaaa agaacgttat tcttattaaa ggtaacgtac
     5581 caggtgctaa gaaatctctt atcaccatca aatcagcagt taaagctgct aaataataag
     5641 aaaggagaaa acagttaaaa atggcaaacg taaaactatt tgaccaaact ggtaaagaag
     5701 ttagcacagt tgaattaaat gatgatatct ttggtatcga accaaacgaa tcagttgttt
     5761 ttgatgttgt aatcagccaa cgtgctagcc ttcgccaagg tactcatgcg gttaaaaacc
     5821 gttcagcagt atcaggtggt ggacgtaaac cttggcgtca aaaaggaact ggacgtgctc
     5881 gtcaaggttc tatccgctca ccacaatggc gtggtggtgg tgttgtcttt ggaccaactc
     5941 cacgttcata tggatacaaa cttccacaaa aagttcgtcg ccttgctttg aaatcagttt
     6001 actcagcaaa agttgctgaa gataaatttg tagctgtaga aagcctttca tttgcagcac
     6061 caaaaacagc tgaatttgca aaggtgcttt cagctcttag cattgataca aaagtacttg
     6121 ttcttgttga agaaggaaat gaatttgcag cactttctgc acgtaacctt ccaaacgtag
     6181 ctgtggcaac agcagcgact gcaagtgttc ttgatatcgt aaacgcagac aaacttcttg
     6241 taacgaaaga agcaatctct acaattgagg aggttcttgc ataatgaatt tgtacgacgt
     6301 aatcaaaaaa ccagttatta ctgaaaaatc aatgtatgcc cttgaagaag gtaaatacac
     6361 atttgaagtt gacacacgtg cgcacaaact gttaatcaag caagctgttg aagctgcatt
     6421 tgacggagtt aaggttgcaa gcgtcaatac tgttaacgtt aaaccaaagg ctaagcgtgt
     6481 tggtcgttac acaggtttta cttcaaaaac taaaaaggct atcatcactc ttacagctga
     6541 ttctaaagca atcgagttgt tcgcagttga agctgaataa tctaaggagg aaataacgtg
     6601 ggtattaaag tttataaacc aacgacaaat ggccgtcgta acatgacttc tttggatttc
     6661 gctgaaatca caacaagcac acctgagaaa tcattgcttg tttctcttaa aaacaaagct
     6721 ggtcgtaaca acaatggtcg cattacagtt cgtcaccaag gtggtggaca caaacgccat
     6781 taccgtttga ttgacttcaa gcgtaacaaa gatggtgttg aagcagttgt taaaacaatc
     6841 gaatacgatc caaaccgtac tgcaaacatt gcacttgtac attacactga cggagttaag
     6901 gcttacatca tcgctcctaa gggtcttgaa gtaggtcaac gtattgtttc tggaccagat
     6961 gcagatatta aggttggtaa tgcacttcca ttagtaaaca ttcctgttgg tacagttgtt
     7021 cacaacattg agcttaagcc tggtaagggt ggagagcttg tacgtgctgc tggagcttct
     7081 gctcaagtac ttggtcaaga aggcaaatac gttcttgttc gtcttcaatc aggtgaagtt
     7141 cgtatgattc ttggaacatg tcgtgcaact gttggtacag ttggtaacga gcaacaatca
     7201 cttgttaaca ttggtaaagc aggacgtagc cgttggaaag gtatccgccc aacagttcgt
     7261 ggttctgtaa tgaaccctaa cgatcaccca catggtggtg gtgaaggtaa agcaccagtt
     7321 ggacgtaaag cgccatctac tccttggggt aaaccagcgc ttggtcttaa aacacgtaac
     7381 aaaaaagcta aatctaacaa gcttcttgtt cgtcgtcgta acgaaaaata agcggcaaat
     7441 ctagcataag cttattcaat cattccgcca gctcggtaga gtttgagctt gctctcatgc
     7501 tcaagccgct gtggtacatt atttaaagga gaaaactaca aaatgggacg tagtcttaaa
     7561 aaaggacctt tcgtcgatga gcatttgatg aaaaaagttg aagctcaagc taatgacgaa
     7621 aagaaaaaag taatcaaaac ttggtcacgt cgttcaacga ttttcccaag tttcatcgga
     7681 tatacaatcg cagtttatga tggccgcaag catgtacctg tgtacattca agaagacatg
     7741 gtaggtcaca agcttggtga atttgcacca actcgtacct acaagggtca cgcagctgac
     7801 gacaagaaaa cacgtcgtta ataggaggag gacacaatgg cagaaattac ttcagctaaa
     7861 gcaatggctc gtacagtgcg tgtttcacct cgtaaaacac gtttagtact tgatcttatc
     7921 cgcggtaaga aagttgctga tgcaatcgca atcttaaaat tcactccaaa caaagcagct
     7981 cgtgttattg agaaaactct taactcagca attgctaacg cagaaaataa ctttggtttg
     8041 gaaaaagcta acttggtagt atctgaaaca tttgcaaacg aaggaccaac aatgaaacgt
     8101 ttccgtccac gtgcaaaggg ctcagcgtca ccaatcaaca agcgaacaac tcacgttaca
     8161 gtagttgtat cagaaaaata aggaggtaaa atcgtgggtc aaaaagtaca tccaattggt
     8221 atgcgtgtcg gaatcattcg tgactgggat gcaaaatggt atgctgaaaa agaatacgcg
     8281 gattaccttc atgaagatct tgcaatccgt aaattcatta acaaagaatt ggcagaggct
     8341 tcagtttcaa caattgaaat tgagcgtgct gtaaataaag ttattgtttc acttcacact
     8401 gcaaagcctg gtatggttat cggtaaaggt ggagcaaatg ttgacgctct tcgcgctcag
     8461 cttaacaaat taactggaaa acaagtacac atcaacatca tcgaaatcaa acagcctgat
     8521 cttgatgccc accttgttgg tgaaaacatt gctcgtcagc ttgagcaacg tgttgctttc
     8581 cgtcgtgctc aaaaacaagc tattcaacgt acaatgcgtg ctggagctaa gggaatcaaa
     8641 actcaagttt caggtcgctt gaacggtgca gatatcgcgc gtagcgaagg ctactcagaa
     8701 ggaactgttc ctcttcacac acttcgtgca gatattgact atgcttggga agaagcagat
     8761 actacatacg gtaaacttgg tgttaaagtt tggatttatc gtggtgaagt tcttccagct
     8821 cgcaaaaaca ctaaaggagg caaataacag atgttagtac ctaaacgtgt taaacaccgt
     8881 cgtgagtttc gtggaaaaat gcgcggtgaa gcaaaaggtg gaaaagaagt atcattcggt
     8941 gaatatggtc ttcaagctac tactagctca tggatcacta accgccaaat cgaagctgct
     9001 cgtatcgcta tgactcgtta catgaagcgt ggtggtaaag tttggattaa aatcttccct
     9061 cacaaatctt atacagctaa agctatcggg gttcgtatgg gttctggtaa gggtgcacct
     9121 gaaggttggg tagcaccagt taagcgtggc aaggttatgt ttgaggttgc tggtgtttct
     9181 gaagaaatcg ctcgtgaagc acttcgtctt gctagccaca agctaccagt taaatgtaaa
     9241 ttcgtaaaac gtgaagcaga ataaggagaa gacatgaaac ttgaagaaat caaaaagttt
     9301 gttgctgagc ttcgtggctt gtctcaagaa gagcttgcta agaaagaaaa cgaactcaaa
     9361 aaagaacttt tcgaccttcg ttttcaagct gcagcaggtc aactagatca aactgctcgt
     9421 ttgaacgaag ttaaaaaaca aattgcacgt gtaaagactg tgcaatctga aatgaaataa
     9481 tagattggga aaggagtatt ctaaataatg gaacgtaatc aacgtaaaac ccttgttgga
     9541 cgtgttgtat ctgacaagat ggacaaaaca atcactgtta tagttgaaac aaagcgtaac
     9601 cacccagtct atggtaaacg tatcaactat tctaaaaaat acaaagcaca tgacgaaaag
     9661 aaccttgcta aagaaggcga tatcgttcgt atcatggaaa ctcgtccact ttcagctaca
     9721 aaacgcttcc gtcttgtaga aatcgtggaa gaagctgtta ttatctaatc aaactaaaag
     9781 gagacaattg aaatgattca acaagaaact cgcttgaaag ttgctgataa tagcggtgct
     9841 cgtgagatct tgactatcaa ggttcttggt ggttcagggc gtaagtttgc taacatcggt
     9901 gacgtcatcg ttgcatctgt aaaacaagct actcctggtg gagcagttaa aaagggtgat
     9961 gttgttaagg ctgttattgt tcgtacaaag agtggtgctc gtcgtccaga cggttcatac
    10021 atcaaatttg atgacaatgc ggctgtcatt attcgtgatg acaagactcc tcgtgggact
    10081 cgtatctttg ggcctgttgc acgtgaattg cgtgagggtg gctacatgaa gatcgtatca
    10141 cttgcaccag aagtacttta attttaatca ttaaacaaac taagtcccct aggctagcct
    10201 agggtgccca taggggcgta agaaaataat aggagaaacc cataatgttt gtaaaaaaag
    10261 gcgacaaggt tcgcgttatt gctggtaagg acaaaggtgt tgaagctgtt gttcttaaag
    10321 cacttccaaa agtaaacaaa gttattgttg aaggcgtagc catcatcaaa aagcatcaaa
    10381 aaccaaacag cgaaaatcct caaggtgcta tcgttgaaaa agaagcacca atccatgcat
    10441 caaacgttca agttcttgat aaaaatggtg ttgctggacg cgttggttac aagtttgtag
    10501 acggcaaaaa agttcgttac aacaaaaaat caggcgaagt gcttgattaa tcacgaagga
    10561 aaggagaagc ataatggcaa atcgtttaaa agaaaaatat actaacgaag taattcctgc
    10621 gttgacagag aagtttaatt acacatcagt tatggctgtg ccaaaggttg agaaaatcgt
    10681 tcttaacatg ggtgtgggtg acgctgtatc aaacgctaaa aaccttgaaa aagctgctgc
    10741 agaattggcg cttatctcag gtcaaaaacc acttattact aaagctaaga aatcaatcgc
    10801 tggcttccgt cttcgtgaag gtgttgctat cggtgcgaag gtgacacttc gtggcgaacg
    10861 catgtacgaa ttcctagaca agctagttag cgtttcactt cctcgtgttc gtgacttcca
    10921 tggtgttcca acaaaatcat ttgatggtcg tggtaactac actcttggtg tgaaagaaca
    10981 gcttatcttc ccagaaatca actttgatga tgttgataaa gtgcgtggtc ttgatattgt
    11041 tatcgtaaca actgctaaca ctgacgaaga atcacgtgaa ttgcttaaag gtcttggaat
    11101 gccttttgca aaataatagg gggtaactaa attggctaaa aaatctatga ttgctaaaaa
    11161 caaacgtcct gcgaagtatt ctacacaagc ttacactcgt tgtgaaaaat gtggacgtcc
    11221 acattctgtt taccgcaagt ttaagctttg ccgcgtttgc ttccgcgagt tggcttacaa
    11281 aggccaaatc ccaggtgttg ttaaagcgtc ttggtaaaat gatgatgtga gagcgttaag
    11341 ctacctaagc aaaaatagga aaattgacga agagtctaaa tactctagga aattttgcac
    11401 ctaaaggtag tagcttgaac tcagttcaaa tgaacaaata atactatcag atattatgtc
    11461 tgattcgatg caaaggcaaa gtgtcaattt gaacacgggc gaaagccggt gtcaaaaaga
    11521 taaacattcc ttggaggttt tccctcctgc ggaagtttcc tattttgact ttggctttta
    11581 gcgccctttg tatcatcgat taactagcaa gtgcagcttg caaactacta gtaagaggag
    11641 aataataaaa tggttatgac tgacccaatt gcagactttt tgacacgtat tcgtaatgct
    11701 aatcaagtaa agcatgaagt gttagaagta cctgcatcaa atattaaaaa agggattgca
    11761 gaaatcctta agcgtgaagg ctttatcaaa aacgttgaag ttattgaaga tggcaaacaa
    11821 ggaattattc gcgtatttct taagtacggt caaaatggtg aacgtgtcat cactaactta
    11881 aaacgtgttt caaaaccagg tcttcgtatt tattctaagc gtgaggatgt tccaaaggtt
    11941 cttaatggac taggaattgc aattatttca acttcagaag gtcttttgac tgataaagaa
    12001 gctcgtcaaa agaacgttgg tggagaagtt atcgcatacg tttggtaatt taagagacaa
    12061 aagccgtaac gaacaatcta aaattagaaa attattgtgg cttgcttgca aacaaaatag
    12121 tttgtctatt ttagatggca gttcgtcggc tgtgctcaaa tgatgaacac tatcaacata
    12181 gcaaacgtaa aagaactaat tgaacatggg ctaaagtctg tgtgaaaaag ataaattttt
    12241 ctagaaacct tggtttcata gtaatgtttc ctattttcac tttgcctttt acgccctaag
    12301 tatcttagtt caccccgtga aaactcgtcg cgtaagcggc ctgataattt aacaggagaa
    12361 aaaattaata tgtcacgtat tggtaataag gttattatta tccctgcagg cgttgaaatc
    12421 attaacaacg acaatgttgt tactgtaaag gggcctaaag gagagctcac tcgtgagttt
    12481 aacaaaaata ttgaaatcaa agtcgaagga aacgaaatga ctcttgtacg tcctgacgac
    12541 tcaaaagaaa tgaaaacaat tcatggtaca actcgtgcaa acttgaataa catggttgtt
    12601 ggagtttcag aaggtttcaa aaaagagctt gaaatgaagg gtgtcggata tcgtgcacag
    12661 cttcaaggct ctaagcttgt tctttcagta ggtaaatctc accaagatga ggtggaagct
    12721 ccagaaggga ttacatttac tgtagctaat ccaacatcaa tttcagttga gggtatcaac
    12781 aaagaagttg ttggtcaaac tgccgcttac attcgtagcc tacgttcacc agagccttac
    12841 aaaggtaaag gtattcgtta cgttggtgag tatgtacgcc ttaaagaagg taaaacaggt
    12901 aaataatgtt cttagtggaa tatggcatag gcttgcttat gtcatgctct acaagctcaa
    12961 ttgataattt gtcggaaaga caaacttaaa tattaagagg tgaaaattgt gatttcgaaa
    13021 ccagataaaa acaaaatccg ccaaaaacgc catcgtcgcg ttcgcggtaa actctctgga
    13081 actgctgatc gcccacgttt gaacgtattc cgttctaata caggcatcta cgctcaagtt
    13141 attgatgacg tagcgggtgt aacgctcgca agtgcatcaa ctcttgataa agaagtttct
    13201 aaaggaacaa aaactgaaca agctgttgta gtcggcaaac ttgttgctga acgtgcggtg
    13261 gctaaaggta tttctgaagt ggtgtttgac cgcggtggat atctctatca tggacgtgtt
    13321 aaagctttgg ctgatgcagc tcgtgaaaac ggattgaaat tctaataggg aggacacaaa
    13381 ataatggcat ttaaagataa tgcagttgaa cttgaagaac gcgttgttgc tattaaccgc
    13441 gttacaaaag ttgttaaagg tggacgtcgt cttcgttttg cagctcttgt agttgttggt
    13501 gatggaaacg gacatgttgg attcggtact ggtaaagctc aggaagtacc agaagctatt
    13561 cgcaaggcag ttgaagctgc taaaaagagc atgattgaag tgccaatggt tggcacaaca
    13621 attcctcacg aggtttacac taactttggt ggagctaaag tattgttgaa gccagctgta
    13681 gaaggttctg gagttgctgc tggtggtgcg gtacgtgccg tcatcgaatt agcaggtatt
    13741 gctgatatta cttcaaaatc tcttggttca aacactccaa tcaacatcgt tcgtgcaact
    13801 gttgaaggat taaaacagct taaacgtgca gaagaagttg ccgcacttcg tggcatctca
    13861 gtttctgact tagcttaaga aaggggatca tcatggctca aattaaaatt actttgacta
    13921 agtctccaat cggacgtaag ccagaacaac gtaaaacggt tgttgccctt ggacttggta
    13981 aattaaactc ttcagttatc aaggaagata atgctgctat tcgtggtatg gtgacagcaa
    14041 tttctcactt ggtgacagtt gaagatgtca aataaagagt tagctagaaa tctctgattt
    14101 cttgcattag catgcagaac cggcttttgt gagttattcc tttgaatgac aagcagtggt
    14161 cggttggtgc atatagcatc aggctatgac atagcttgat catgtatagg cgagtttcta
    14221 tggagagtcc tttcccttca tagaggcgct agcattttac aaaaaaagga gaaaaaatga
    14281 aacttcatga attgaagcct gccaaaggct ctcgtaaagt ccgcaatcgt gttggacgcg
    14341 gtacttcatc aggcaatggt aaaacatctg gacgcggtca aaaaggtcaa aaggctcgta
    14401 gtggtggtgg cgtacgtcta ggctttgaag gtggacaaac acccttgttc cgtcgtattc
    14461 caaagcgtgg atttacaaat atcaacacta aagagtatgc tcttgttaac cttgatcaat
    14521 taaacgcttt tgaagatggc acagaagtaa ctccagttgt tcttaaggaa gctggaatcg
    14581 ttcgtgctga aaagtcaggc gttaaaattc ttggtaacgg cgaattgact aaaaaattga
    14641 ctgttaaagc agcgaaattt tcaaaatctg ctgaagcagc cattactgct aagggtggtt
    14701 caatagaagt catctaatga ggggatactc attatgttct taaaaatact caaagacgca
    14761 ttgaagataa agaatgttag aaataaaata ttttttacaa tctttattat ccttatattc
    14821 cgtattggaa cacatatcac tgttcctggt gtaaatgcaa aaagcttaga gcagctgagt
    14881 gagcttccct tcctaaatat gttgaacttg gtcagcggta atgcaatgag aaacttttca
    14941 gttttctcaa tgggtgttag tccctatatt acagcctcaa tcgttgttca gctattgcag
    15001 atggatattt tgccgaagtt tgttgagtgg ggaaaacaag gtgaggttgg ccgtcgtaag
    15061 ctaaaccaag cgacgcgcta tatttccctt gtcttagcct ttgctcaatc tatcggtatt
    15121 acagcgggtt ttaacacctt atcaagtgtg gccctagtca aaacaccaga tgtaagaacc
    15181 tatttactga ttggagcttt actgacaaca ggtagtgtga ttgtgacctg gcttggtgaa
    15241 cagattaccg ataaaggctt tggtaatggg gtgtctatga ttatctttgc aggtatcatt
    15301 tcctctattc caaatgctat tgcaaccatt cgtgaggatt attttgtcaa tgtgaagtca
    15361 ggtgacctac agtcatctta tatcgttgtt ggtattctca ttcttgcagt gcttgctatc
    15421 gtctttttca caacgtatgt tcagcaggcg gaatataaaa ttccaatcca atatacaaag
    15481 cttgttcagg gtgcgcctac aagctcatac cttcccttaa aagtaaatcc agctggtgtt
    15541 attcccgtta tctttgccag ctcgattaca acaattccaa gtacgattat cccgttcttt
    15601 caaaatggca gagatattcc atggttgaca actttgcaag gaatttttaa ctatcaatct
    15661 ccaacaggaa tgattgttta tgccttgtta attatcctgt tttcattctt ctataccttt
    15721 gttcaagtaa atcctgagaa aacagctgaa aatctacaga agaattcgtc ctatattcca
    15781 agtgttagac ctggacgaga aacagaagaa tttatgtcat ccttgctaaa gaaattggca
    15841 actgtgggtg ctatcttcct agcatttata tctcttgttc caattgcggc acaacaagct
    15901 cttaacctat cttctagtat tgcattaggt ggaactagct tgctgatttt gatttcgaca
    15961 ggtatcgaag gtatgaagca gcttgaaggt taccttctca agagaaaata tgtcggattt
    16021 atgaatatta cagaatagaa tatgggttga cactgtcaac cttctatttt gtttttaaat
    16081 gacaataaga tttacagagc cttggttcct atcttcttat tgccatttga aaacaaaaac
    16141 aaggaaaact aaatttccta ttatctttat gtcaaaagag gagaaaaaga tgaatctttt
    16201 aatcatgggc ttacctggtg ccggtaaggg tacacaggct gcaaagattg ttgaaacctt
    16261 tgagcttatt catatttcaa caggagatat gttccgcgct gcaatggcta atcagactga
    16321 aatgggagtt cttgcgaaat cttatatcga taagggtgat ttggtgccag atgaggtaac
    16381 caatggtatc gttaaagaac gcttagcaca agctgatatt aaagaaaagg gatttctttt
    16441 agatggctat cctcgtacca ttgagcaggc acatgcctta gatgaaacct taaaagcatt
    16501 gggacttacg ttagatggtg tgatcaacat tgaggttgac cctgcgtcac tcattgacag
    16561 gcttagcggt cgtatcatca acaaaaaaac aggggaaacc ttccataaga tctttaaccc
    16621 accagtggga gactataagg aagaggactt ttatcaacgt gaagatgata agcctgaaac
    16681 agttaagcgt cgcttagatg ttaatattgc acaaggtgag cctattatca agcattatcg
    16741 tcaagcaggc attgttcgtg acattgacgg aaacaaggac atttctgagg tctttgctga
    16801 cataaaaaag gtcatcgaaa acctgaaata aattccagaa aatcgcttgc gaaagtgatt
    16861 ttatcgtgat atactagact agtctgactt ataattgtta cctctgtgct cagaggacat
    16921 caaatcgaaa tttagggggt acttttgcgt ggcaaaagaa gacgtgattg aaattgaagg
    16981 taaagttgtc gaaactatgc caaatgcaat gtttactgtt gaattggaaa atggacatca
    17041 gattttagca accgtatcag gaaagatccg caaaaattac attcgtattt tagtgggtga
    17101 tcgtgttact gtagagatga gtccttacga cttgacacgt ggacgtatca cataccgctt
    17161 taaatagtcg aaataattgg agggattaaa acatgaaggt aagaccatcg gttaaaccaa
    17221 tttgcgaata ctgcaaggtt attcgtcgta acggtcgtgt tatggtaatt tgtccgacaa
    17281 atccaaaaca caagcaacgt caaggataag atagaaagga gaaaaaatgg ctcgtattgc
    17341 tggagttgat attccaaatg ataagcgtgt agtaatttca cttacctatg tgtatggaat
    17401 tggtcttgca acatctaaaa aaatcttagc agcagcaggt gtctctgagg acattcgtgt
    17461 taaagatttg acatcagatc aagaagacgc tatccgtcgc gaagtggata caattaaagt
    17521 tgaaggtgat cttcgtcgtg aagtaaacct aaatatcaag cgtttgatgg aaatcggttc
    17581 atatcgtgga attcgtcacc gtcgtggact tcctgtacgt ggacaaaaca caaaaaacaa
    17641 tgctcgtact cgtaaaggta aagctgttgc gattgcaggt aagaaaaaat aaaataggag
    17701 gtaaaaaaat tggctaaacc aacacgtaag cgtcgtgtga aaaagaacat cgaatctggt
    17761 gttgcacata ttcacgctac atttaataac actattgtta tgattacaga tgtgcacggt
    17821 aatgctttag catggtcatc agccggtgct cttggtttta agggttctcg taagtcaact
    17881 ccttttgctg ctcaaatggc tgcagaggct gctgcgaaat ctgcacaaga acatggttta
    17941 aaaactgttg aagttactgt aaaaggtcct ggttcaggtc gtgaatcagc tattcgtgcc
    18001 ctagctgctg ccggtcttga agtaactgcc attcgtgatg tgactcctgt accgcataat
    18061 ggtgctcgtc ctccaaaacg tcgtcgtgta taatcacagt aacaaatagt acacaagttt
    18121 cgtttcgagg ggtgaaagaa tgattgagtt tgaaaaacca ataataacaa aaattgatga
    18181 aaataaagat tacggtagat ttgtaatcga accacttgaa cgtggatatg gtacaactct
    18241 aggtaattca cttcgtcgtg tactcttgtc ttcacttcca ggtgcagctg ttacatcaat
    18301 cagaattgat ggagtactac acgaatttga tacaatccca ggtgtacgtg aagatgtcat
    18361 gcaaattatc cttaatgtta agggacttgc tgtgaaatca tacgtcgaag acgaaaagat
    18421 tatcgagctt gatgtagaag gtccagcaga ggtaacagct ggagatattc tcacagatag
    18481 cgatatcgaa cttgttaacc ctgatcatta tctttttact attgctgatg gttatacatt
    18541 gaaggcttca atgactgtcg ctaaaaaacg cggctatgta ccagcagagg gtaataaaaa
    18601 agatgatgca cctgtgggga cgttggcagt agattcaatc tatacgccag taaaaaaggt
    18661 taattatcaa gttgagcctg ctcgtgtagg tagtaatgac ggctttgata aattgactat
    18721 tgaaatcatg acaaacggaa caattattcc cgaagatgcc ttaggtttat ctgctcgagt
    18781 tttaatcgaa cacttgaatt tatttactga tttaacagat gttgcaaagg caactgaagt
    18841 gatgaaggaa gctgaaaaag tgaacgatga aaaggtactt gatcgcacta ttgaggaact
    18901 tgatttgtcc gtacgctcat ataactgctt gaaacgtgcc ggtattaata ctgtcttcga
    18961 tttaacagaa aaatctgagc ctgaaatgat gaaggtccgt aaccttggac gtaagagtct
    19021 tgaggaagta aaggtcaagc ttgctgactt aggtttggga ctaaaaaacg ataaataaca
    19081 taggaggata aaatggctta ccgtaaacta ggacgcacta gctcacaacg taaagcaatg
    19141 cttcgtgact taacgacaga tcttttgatt aacgaatcaa ttgtaacgac agaagcacgt
    19201 gcaaaggaaa tccgtaaaac agttgaaaaa atgattactc ttggtaaacg tggtgatctt
    19261 catgctcgtc gccaagcagc tgcatacgtt cgtaacgaaa tcgcatcaga aaactatgat
    19321 gaagctactg ataaatacac atcaacaaca gctcttcaaa aacttttctc tgaaattgcg
    19381 cctcgttatg cagaacgcaa cggtggatac actcgtatcc ttaaaacaga accacgccgc
    19441 ggagatgctg ctccaatggc gattattgaa ttagtttaat ttttatcaat tttgttgagt
    19501 gttatgatga tggagcagtt cctttaagct gttcttagtc tagctctggt ctaccgctag
    19561 gacctttcct agcggtaaca ctcaccatgt tgagaataag taacgcttgt ttacgaaagg
    19621 tctctaagct gtaggtgccc ttcgtaagca ggcgttttgt tgtgactcca tgttaactgt
    19681 agtagatgac taatatctaa tatctagaga ggatcagctt ggtgctctct tttctgatat
    19741 taaaagcatt gggaatcttg gttttgaagt tcttaaagct cctaaagcca aagtctttcg
    19801 cttgatgtct ttggtcatct tgttagtggt ctccggctta gcattggaat aaggtagttc
    19861 aaagcattgg tgatgtaaga tctatacttc ctgaaggtct tgaaaaccgt tttgaaggtg
    19921 tgattgacct gtagcgggag tagattagat caatggcgtt tggctgcttt gaaaatttag
    19981 gtgacaattg tttttgtatc tttgtttaaa aatggtataa tattaaaaca ttaaacaaaa
    20041 tgtacataaa aaagccatat aaaagaatga tattaagata atgtgatcaa tagttttaga
    20101 aaatgaatgt gtaaggttaa ggtatgcccc cttgatataa tgctagtttt acgaagaggc
    20161 attctgtaca gacataatgc actcttacaa atgatacggt aattgctcaa caaggcgcaa
    20221 cagccttggc aaatgtaata tttgccttag ctagcagcga attagttacg cttgatacat
    20281 agacaagggt ttctggcata cagcagcaga tggtgtgcct gtctcagaga gtggctgctt
    20341 ggcttatcct attcatgttt taaaacttac aggaggtgtt atgtggcctt tggtcgatgg
    20401 atatttagct aggtgaacag ctattagctg taaatatgag gtaggagctt tagtttgcat
    20461 gatgttaaat gaattgaaac agacttagga aagcttggct tagcaactat cacgcaagtt
    20521 cttaacaacg ataaagatcg tatgggaaaa tatgatcaag catcaacgga catgagatgt
    20581 gttttatgaa gaaaccatta tacttttata agacttattt agttgttttt ctttgcggac
    20641 ttgtttgagg agtagtctac ataggcaata ggctcaggct tacagcactt aggagacatt
    20701 agagcatgag aagcactaac tggctagtga tagaaaagta atagcacagt gtttttataa
    20761 ctaacaagag gagtagacat tctatgagta ttgacatgta tttgagctta tctgaagagc
    20821 aggcacagag tgtagaggct gtcttagcta ggcgacaaac agcctatcaa tccttacagg
    20881 agaccttgat ccaattgatt tctaacagtc ctgatttatc agggcggacc tatgattctg
    20941 ctaaggctta tagtagtcaa gtgctaattc ctttgttaaa ggggtgtatg cttttagatg
    21001 aggcgattat aacagcctgt aagaggctac ctagtgagta ccgtagtcag gtagaccaaa
    21061 ttgatttgaa ggagagtgat ctggttgagc gtattgccca gttcgatcat gtgattggtc
    21121 ggtacatgga tttgattagt attgaataca gtagagagga gcctagctat tcttatatct
    21181 ctcatttaag atcagctgag cagctccatc gggccgttaa gcggcgtctt gaggagatat
    21241 tgcgaaggct aaggcatttt gataccaact cagttcacct tttttcgact attcagactt
    21301 tggcagcagc ggtacaaata ggcatgcgtc aagctaggac ctcgtggcat gcaggaagtc
    21361 aggtatttgt gatttcagag gatatggcat gggccgatac gattaattct aagtggtcaa
    21421 aaagtaaagg gttaagctat cttagtgatt atgtttacga cccagatgtg ctctctaaga
    21481 gagcagctat taatcactct tggattaaaa caggctatac tatgtctaaa aattttggca
    21541 aagctgtttc aaaagattat acaaaagcaa gctttttgag ctatggtaag gcagccaagg
    21601 cgactggctg gacttctatg gcagtagata ctggaataac tagtgtaagg gaatacaata
    21661 agaaaaatag tagagcctat ggcagtgagg gcaaggcgct tattcatgct agtgtggctc
    21721 aaatcaagag catgggacct atagaagggg cgataattgg cagtaaagct ggaccttggg
    21781 gagcattaat ggggtttgtt acaggaggca ttaatgttac ttggggagta gtgcatccag
    21841 agtctaagga caacatgttt ttatggatac aagataaaat ggatgatgtt tacgattcga
    21901 ttgttcagac agatcttggc aaagggacgc accatgctaa agaaagtgtc aaaggtcata
    21961 tcggtcgagc tattgtaagg acatgggact ttgtcagtca atcatttggt aaaggagtgg
    22021 gctatgacat ttaaagatca gctttttagt gggacgtttg agcaatcaaa aaagattgtg
    22081 tctaaaagta tattgacaga agaaggtgcg cagattggag tattctcatc tatgagtcta
    22141 tggaagagaa taacaggctt gatgatgttg ccattatttg ctatttcata tggagtagga
    22201 gttgtgttac ctgaacactt tcaacaatca acagaaggag ttcaagctat ttcattggct
    22261 gcaatagaga ttattgccag attaggacag ttcagtcgat actttatcat ttgttttatt
    22321 tgtatgtctg ttggattaat tattagtaat atccttccaa agcctaacta ggcttatcaa
    22381 ttattatatg gcaatgctac tcttattata cttagtatta caactattat ctcagccttc
    22441 cctttaactg ctggccttac aattgcagct tttggctgga tcggtttttt gcttcagcta
    22501 ttgctttgcc tttatttgtg gaaggtttgt gtcatagata agtgtcaaca gctacgcaca
    22561 gcaatttatc aagaaagcac catagcacct gattggggca gtaagctagt aagctttatt
    22621 aagtcttatg gtggtatctt attaggcctc tctgttctca accgctggac tctcaatcta
    22681 ggagagctag tcaaggaaag ccctggtttg ttgagttttc tgtacggctg gatttttcta
    22741 ttgttcatgt ttttgatgct atttgcactg ggtcaagcgt taaaaaatac catcatagcc
    22801 tattattttt ttagatatca aaaagaatac cgcaagcatt ttaatataag cgatgagcag
    22861 tggtacggta aatggcgttt aaaaatatta ttaaaataaa cgatataagg agtaatcata
    22921 tgcaaaaaga attattaccg ttaggaagtg ttgtctatct agagggagca acaagcaagc
    22981 taatgattgt cggacgtggt cctatatttg aatctaatgg ccaaaatgtc tacagtgatt
    23041 atgttggagt aatgtatcca gaagggatca atccagaaga cgcgattttt ttcaaccatg
    23101 aagatattgc aaaaacagtc tttgaaggct tcaaggacga agaagaacaa cgctttttag
    23161 aagtgtattc tgattgggag agtactttag aaatttccaa aataaagcta tagatgaact
    23221 gtagcagata tatttgtcag tagattgtca tgattatatt gaaagattat gactttctct
    23281 ggcttaaata cctctaaagt tccaaagttt agaaaaggct ttaaaatgag tgttataata
    23341 gcatttatgc tcattaaata aaggtagcat ttcaatagaa tcggtaaaaa aa
//
LOCUS       DARYYD010000033        22832 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.033, whole genome shotgun sequence.
ACCESSION   DARYYD010000033 DARYYD010000000
VERSION     DARYYD010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22832
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.033"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(123..934)
                     /locus_tag="TV188_001260"
                     /pseudo
     CDS             complement(123..934)
                     /locus_tag="TV188_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983364.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
     gene            1193..2653
                     /locus_tag="TV188_001261"
     CDS             1193..2653
                     /locus_tag="TV188_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEL1534614.1"
                     /translation="MEKFFKLKENGTTVSTELMAGVTTFFAMSYILFVNPSILSAAGM
                     PSQAVFLATIIAAAISTLIMGLFANVPYALAPGMGLNAFFTYTVVFSLGFSWQEALAI
                     VFLCGLFNIFITVTKLRKSIIKAIPVSLQHAIGGGIGVFVAYLGFKNANLITFSLSSA
                     EIVTVNGVEPAKATAETFANGVFSVNANGGVVPAISTFTDPSVLLAVFGLLLTAVLVL
                     KNVRGAILIGITVTTLAGIPIGVVDLSAVNFADNHISSAFAELGTTFLAAFGGMASLF
                     SDSSRLPLVLMTIFAFSLSDTFDTIGTFVGTGRRTGIFSEEDERALENSSGFSSKMDR
                     ALFADAIGTSIGALFGTSNTTTYVESAAGIAEGGRTGLTAVSTAVCFVLSVLLLPIVG
                     IVPAAATAPALIIVGVMMVSSFLDVDWSDFDVALPSFFAAFFMALCYSISYGVAGSFI
                     FYCLVKLVKGKTKEIHPILWGATFLFVLNFIILALL"
     gene            3019..3462
                     /gene="tsaE"
                     /locus_tag="TV188_001262"
     CDS             3019..3462
                     /gene="tsaE"
                     /locus_tag="TV188_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEL1534615.1"
                     /translation="MFYSKNENELIAYGQGIGRQLKAGDVLVLTGDLGAGKTTLTKGV
                     AKGLGIDQMIKSPTYTIAREYEGRLPLYHLDVYRIGDDPDSIDLDDFIFGGGVTVIEW
                     GELLAKGTLHDYLEILITKTETGRQVDYLAHGHRSEALLEELKHV"
     gene            3455..3982
                     /locus_tag="TV188_001263"
     CDS             3455..3982
                     /locus_tag="TV188_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1534616.1"
                     /translation="MSEQVVTIEEAKASDASALITLIKEAADETDFITGTEDVIAATV
                     EVLECFLEASQESLTDICLLLKVGDILAGLLNIAGKAYRETSYVGDCFMLVLKPYRNH
                     GLGQLLMETTLDWARETKQLCALELEVQARNTCAYHIYEKYGFKIEGVKRKDVKSRNG
                     DYQDVYLMRKYLERE"
     gene            3983..5245
                     /locus_tag="TV188_001264"
     CDS             3983..5245
                     /locus_tag="TV188_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEL1534617.1"
                     /translation="MKIGKKIFLMLTAIVLLTLGAMGVYLTNAYTFSTGELSKTFKDF
                     ATSSKKSDAIQQTEPFSILLMGVDTGSSHRTSTWQGNSDSMILVTINPKTKKTTMTSL
                     ERDILITLSGPNDNEMNGAEAKLNAAYAAGGAQMAIMTVQDLLNITIDKYVQINMQGL
                     IDLVNAVGGITVTNEFDFPISIADNEPEYQATVAPGTHKINGEQALVYARMRYDDPEG
                     DYGRQKRQREVIQKVLKKILALNSISSYRKILSAVSGNMQTNIEISSRTIPNLLGYTD
                     ALKNIKTYQLKGEGATLSDGGSYQIVTSDHLLEIQNRIRAELGLEKLSQLKTTATVYE
                     NLYGSLKTQSTQDSSYYYNSGSLPAYTDSSTQYSTYSSETSSSSSYQDTTAGTQESGA
                     ANVTPSPQADSPAEQQSSGATTGTPAAP"
     gene            complement(5415..5711)
                     /locus_tag="TV188_001265"
     CDS             complement(5415..5711)
                     /locus_tag="TV188_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HEL1534618.1"
                     /translation="MTLKTMTTIGLTSVLAYQVYRKRHQIKETLVAMQTSKKAIQADV
                     DRIKANLAIIQKEARTLQAAGTELAYKWQAFNQEAQAHLTEIQQRMSKYQQETP"
     gene            complement(5708..6127)
                     /locus_tag="TV188_001266"
     CDS             complement(5708..6127)
                     /locus_tag="TV188_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003108095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEL1534619.1"
                     /translation="MENCIFCSIISGEIPSSKVYEDEQVLAFLDISQTTAGHTLLIPK
                     KHVRNILAMDAETASQTFERLPKIARAIQKATGATAMNIINNNEELAGQTVFHAHVHL
                     VPRYSQEDGIAIQYTTHEPDFPALAALAQQISQEISQ"
     gene            complement(6580..7023)
                     /locus_tag="TV188_001267"
     CDS             complement(6580..7023)
                     /locus_tag="TV188_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534620.1"
                     /translation="MNLSRFLTFGLVSLSALSISGLVQTEAKANEWQTIFEKPQEVVI
                     TDGWQTISEKPQEVSTANEWQVSSEEAQESVPDKFSQNEDPSLWAVPDKFSQNEDPSL
                     WAVPDKFSQNEDPSLWAVPDKFSQNEDPSLWAVPDKFSQNEDPSL"
     gene            7560..8285
                     /locus_tag="TV188_001268"
     CDS             7560..8285
                     /locus_tag="TV188_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019322154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534621.1"
                     /translation="MLNIENVTGGYLNIPVLKDISFSVGNGELVGLIGLNGAGKSTTI
                     NEIIGFLKPYKGRISIDGLTLAEHEADYRKKIGFIPETPSLYEELTLAEHINTVAMAY
                     DIDVELAHKRAEPFLELFRLTDKLDWFPVHFSKGMKQKVMIICAFVIDPSLFILDEPF
                     LGLDPLAIADLIKALEVEKAKGKSILMSTHVLDSAEKMCDRFVILHQGQVRAQGTLAD
                     LQAVFGDASASLNDIYLALTKEG"
     gene            8289..9323
                     /locus_tag="TV188_001269"
     CDS             8289..9323
                     /locus_tag="TV188_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1534622.1"
                     /translation="MKALFRKRRQEFQHKHTKYLPYVFNDHFVLVLLFLLGFILFQYS
                     QLLKHFPANPLPIQLGLLIAVLFLLNLGSVATYLEKADQHFLLTKEAEVIAHIRSAER
                     LSFILWSSLQTVLLLPLFPLFQRLGVSLLAFVLLLGVLVLAKRLLLKRKVASFLSSKG
                     LDWEKAIAFEADRQQAILKFYALFTNVKGISTKVKERPYLNPILKLIKADSKKVWTNL
                     YLRAFLRSSDYLGLWLRLLLLSCLSLAFISNPYLAVGLALVFHYLSLFQLLSLYHHYD
                     YHYMSGLYPTKPQHKQRNLLSLLRQLSGLMLIVNLVLCRSWQNALVLIVAMGLLNLLY
                     LPYKLKKMID"
     gene            9386..10177
                     /locus_tag="TV188_001270"
     CDS             9386..10177
                     /locus_tag="TV188_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEL1534623.1"
                     /translation="MTTTEQDLVLTPLRGKSGKAYKGTYPNGESVFIKLNTTPILPAL
                     AKEQIAPQLLWAKRMGNGDMMSAQEWLNGRTLTREDMNSKQIVHILLRLHKSKQLVNQ
                     LLQLNYKIENPYDLLVDFEQNAPLQIQQNSYLQAIVKELKRSLPEFRSEVATIVHGDI
                     KHSNWVITTSGMIFLVDWDCVRLTDRMYDVAYLLSHYIPRSRWADWLSYYGYKNNDKV
                     MQKIIWYAQFSYLTQILRCFDKRDMEHVNQEIYALRKFREMFRKK"
     gene            10177..10812
                     /gene="trmB"
                     /locus_tag="TV188_001271"
     CDS             10177..10812
                     /gene="trmB"
                     /locus_tag="TV188_001271"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEL1534624.1"
                     /translation="MRVRKRKGAQEHLENNPHYVILEPEAAKGRWCEVFGNDHPIHIE
                     VGSGKGAFITGMALKNPEINYIGIDIQLSVLSYALDKVLASQAPNVRLLRVDGSSLTN
                     YFDAGEVDMMYLNFSDPWPKSRHEKRRLTYKSFLDTYKQILPENGEIHFKTDNRGLFE
                     YSLASFSQYGMTLKQVWLDLHASDYQGNVMTEYEARFAKKGQIIYRLEATF"
     gene            10872..10958
                     /locus_tag="TV188_001272"
     tRNA            10872..10958
                     /locus_tag="TV188_001272"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10906..10908,aa:Ser,seq:gga)
     gene            complement(11005..12084)
                     /locus_tag="TV188_001273"
     CDS             complement(11005..12084)
                     /locus_tag="TV188_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1534625.1"
                     /translation="MAFYRKLDSGWEYRITYRDSQGKKREKSKRGFKTKTLAKVAAQQ
                     AETDLNTLTADLLDITVLDYNKRWADIYKRPHITAKTWQTYTKNFKHIEHYFGTRKLK
                     SITHTFYQQVLNDFGEKVAQQTLDKFHYQIKGACKMAIRDGIIRDNFADEAIVRSQKP
                     AKEESEKFMEESEYLAFIKTAKEKIKYPSYLTTYIIAITGLRFAEAQGLTWKDIDFDN
                     GYVDVNKTFDYSISQNFRPTKNEQSIRKVPIDNNSVELLKYFKDNHYQDNKLSRICFG
                     ASNNATNKVIKRVTGRNLTNHSLRHTYASYLIAQGVDLISVSKLLGHENLNITLKVYA
                     HQIESLKEKNDHQVKNIFQNLKIDG"
     gene            complement(12203..12754)
                     /locus_tag="TV188_001274"
     CDS             complement(12203..12754)
                     /locus_tag="TV188_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534626.1"
                     /translation="MDITKLKGFAIAAAGKAKDGAIKANELRKKASQESKMILPPALN
                     LGLGTPTAIRKTIDGKYYIGFYSETPELYEFVNLQFDGSRIIEKTVTKGKTTQRGRSG
                     SVLGGAAIGTVLAPGVGTIVGGMTGGARKKKGTINTTATTTSEEIPGKATVALRNIQT
                     GEVKTLKTKLTQAQYVNVNNFFK"
     gene            complement(12765..13148)
                     /locus_tag="TV188_001275"
     CDS             complement(12765..13148)
                     /locus_tag="TV188_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEL1534627.1"
                     /translation="MMTPETVCQEKGIDLVYFDGRGTNTPGMFNKKHNVIAIDTYLDG
                     IYKHKVIYHELGHREHTASYYKLNKEKAELQADRCMIHHLLKEELSYWDNMEDFNYIQ
                     FMEKYELTSIADEVMVKEELEFLIS"
     gene            complement(13162..13521)
                     /locus_tag="TV188_001276"
     CDS             complement(13162..13521)
                     /locus_tag="TV188_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1534628.1"
                     /translation="MTMFEVYSRIEALAKKRGVSLQKVATDIGLSENYIYNLKSKKTA
                     NTDPIEKIANYFNVSTDYLLGRTDNPKIAQDGHASVAIDLKKDAEETFFFDGHELNDE
                     DIDLITSILETRIKNRK"
     gene            14277..14468
                     /locus_tag="TV188_001277"
     CDS             14277..14468
                     /locus_tag="TV188_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534629.1"
                     /translation="MSDNTVAVEKIKKYLLDNKLKQVDLAVTYNKEPQDVANILAGRK
                     KDPASNRFVLKVISDLKIR"
     gene            14489..14719
                     /locus_tag="TV188_001278"
     CDS             14489..14719
                     /locus_tag="TV188_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534630.1"
                     /translation="MLNAILERNLMTDAEKQNYDALFINIFERLEKLEEGYDFSSVAT
                     TTGVQNSGGVQYRECQEDGTVVKTVSKRSLGY"
     gene            14785..15060
                     /locus_tag="TV188_001279"
     CDS             14785..15060
                     /locus_tag="TV188_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1534631.1"
                     /translation="MDSRLLQMLDEFEAGLIDRKVKVMKMINNETETYPLELNKKQVS
                     KMFGIDPKTFDARFNSHKDFPRIETGGREKYPRDLVIEWYHRNWSIT"
     gene            15057..15227
                     /locus_tag="TV188_001280"
     CDS             15057..15227
                     /locus_tag="TV188_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534632.1"
                     /translation="MNKLELFLLATTIVLAIIARVQYEIIKKHNSPENKRKIFREVAL
                     ENSKKWSAERYV"
     gene            15220..15423
                     /locus_tag="TV188_001281"
     CDS             15220..15423
                     /locus_tag="TV188_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534633.1"
                     /translation="MSKWELQKQLLENATDFESTVEALLDLNESGEISDLELLLNLKD
                     KFRSYSKEKIRILNEILKLGGAE"
     gene            15420..15806
                     /locus_tag="TV188_001282"
     CDS             15420..15806
                     /locus_tag="TV188_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534634.1"
                     /translation="MMTTFEKIIKKINRIEGELVKPEAERRDSLPILSAQLGSIKQDL
                     KLMLWIELPSLNNVEKYEALYQGNDFKFSETFLERQATRKAFWRRLAKETFKEDQDRR
                     NFVKLAEKEFKGATLSWQEFLWGKKK"
     gene            15803..15955
                     /locus_tag="TV188_001283"
     CDS             15803..15955
                     /locus_tag="TV188_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534635.1"
                     /translation="MNISIKLIGETLAGLNDILRQGGLSCSQNQALADAVFILTALKQ
                     VIEERK"
     gene            15952..16155
                     /locus_tag="TV188_001284"
     CDS             15952..16155
                     /locus_tag="TV188_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534636.1"
                     /translation="MNYLEYALVYLERELEIIDNEVIEVELPGGDWEFVPNPYYEKGL
                     HDSPHYRSQVAKDILDIKGLLGR"
     gene            16243..16542
                     /locus_tag="TV188_001285"
     CDS             16243..16542
                     /locus_tag="TV188_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534637.1"
                     /translation="MIEVTFKAESMAGVFDAMREALDMPKTVTKDVVEEKPAPKKKEE
                     SVTLTLADIKKMAKAKVEEGKSKDIKEVLKEMNVAKVGELEEYQFAEFVEKLEAL"
     gene            16542..17699
                     /locus_tag="TV188_001286"
     CDS             16542..17699
                     /locus_tag="TV188_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2800 domain-containing protein"
                     /protein_id="HEL1534638.1"
                     /translation="MPVENHALLSASSAHRWLYCPMLPRLEADYPSRDTVYTQEGTSA
                     HELSEIKLMYKSGKITKRKFNTLTKTFKENSDFYNEEMEEMTELYTDIVMEHLNAYEN
                     AEIELEKRVDFSDWVPGGFGTSDVVILADGVIEIIDLKYGKGMPVSANQNPQMGLYAL
                     GAYASYDMVYDFDRIKMTIIQPRLDSVSSVDIYVEELLYWADNVVLPMAAQADAGIGD
                     WNLSEKVLQWSPVAAKLVPRAQENWELIDKYDYQEPVYLSDEAVAEILDKASAIKKWV
                     ESVEAYALKEALSGKEVPGYKIVEGRSNRVITDKDKAIDILQDNGFDDEIFKPKELLA
                     MGALEKLIGKTTFADLLAEVIDKPQGKPVLVPEKDKRPAINSLEQAIKDFE"
     gene            17713..18276
                     /locus_tag="TV188_001287"
     CDS             17713..18276
                     /locus_tag="TV188_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2815 family protein"
                     /protein_id="HEL1534639.1"
                     /translation="MTTTPNTTKVVTGKVRLSYVALLEPKAFEGQEAKYSTVILIPKT
                     DKVTIKKIKDAQKAAYEAAKDNKLKGVKWERVKTTLRDGDEEMDTEEHPEYAGHVFMS
                     VSSKTKPQIIDKYKNPVDSADEVYSGVYARVSLNAYAYNTAGNKGISCGLNNVQIVAK
                     GDYLGGRSSADADFDEWNEEEDEDDIL"
     gene            18319..20241
                     /locus_tag="TV188_001288"
     CDS             18319..20241
                     /locus_tag="TV188_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase"
                     /protein_id="HEL1534640.1"
                     /translation="MRHLNIDIETYSSNDIKNGVYKYADAEDFEILLFAYSIDGGEVE
                     CLDLTRQSLPEDIKDMLFDDKVRKHAFNAQFERVCLSRYLGLPYYLDPCQWQCTMVLA
                     QELGLPSSLEKCALYLKLAQEKDTSGKNLIRYFSLPCKPSKTNGGRTRNLPEHAPEKW
                     QMFIDYCIQDVVVEMAIAEKLESVPVHDREWDYYACDQRINDRGVALDKELVASALYC
                     KDVKMESLSGELKAITGLANPNSRAQLLPWLKEHGYSANGLTKADVEQELKTAEGELK
                     RVLELKLQTAMSSLKKYEAMERAMCSDGRVHGLLQFYGASRTGRWAGRVVQVQNLARN
                     YIKDLDDAREYVKKRDIDAVEILYDSLNDTLKQLVRTALVAKDGCTFYVSDFSAIEAR
                     VIAWFAGEQWRLDVFSTHGKIYEASASQMFGIPIEEIDKELRQKGKISELALGYQGGP
                     GALKQMGALNMGVKEEELQGLVDDWRRANKKIVQFWKDVQRAAIKAIKSRAPIKLGKL
                     RFRYRKGFLFITLPSGRNLAYARAKVEPGDYGDKIIYEGQGDKAYFTAQETYGGKLVE
                     NIVQATARDILAEALLRIEAAGYGVVFHVHDEAIIEGSGLTIEEVNDLMAQAPEWAEG
                     LPLNSEGYVTKYYMKD"
     gene            20246..22630
                     /locus_tag="TV188_001289"
     CDS             20246..22630
                     /locus_tag="TV188_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEL1534641.1"
                     /translation="MKQEKLIVKSSPLQELHIATGSSRTAKTWKNITLTWQELVERLE
                     KPTVTQETFAEYQKMSRAEKGQAKDVGGFVGGWLKQGKRKNENVQSRSLVALDADSPS
                     KDFLDRLDLLADYAYVLYSTHSHSKKAAKYRLIIPTDRLMMPDEYEPVARYLANQLGM
                     SNFDDTTYQSVRLMFWPSHSRDADFTFKYNDEAFLSVDEVLDTYPDWHDSSFWPESPT
                     HAVKRQREAKKQGDPLSKKGLIGAFCRNYDIRQAIATFLPEVYEEGTTPDRYTYTDGS
                     TANGLVIYDDVFAYSHHGTDPVGDTLVNAYDLVRIHKFGEQDSEAKDNTPTNKLPSSK
                     AMNAFVCDLPEIKDYLMAEALGDFDEELPVEDDRSWLEIDERGEPEVNSYLLATQIIK
                     EVPIYWDGLEFLRYDAKKGIWLPNAEEYLKSYISTKKLGKITKIRHISETIVAIKAQA
                     FSSEVFTESDLNKIVLVNGVYDLRDNSFKTKFDPELHARSSHPVAYAPEAACETFEGF
                     LRETVGAENIDFIFEWFGYNFYREYTIQKMLFIYGSGGTGKSTLINILREMIGADNYS
                     AVTLQYLMQERFAKIGLYRKTANFDTDAKPQYLADGATLKMLTGEDTIHADRKNKEPI
                     NFYNYAKLSFAMNELPPMRDFSGGLKRRMMILEMDKVLTQEVKAKYPLDKIMSEVPGI
                     FNRAMEGLRNALSKRDFSISASMRSSVEKWEKGNDVVAMFLEDECELGEDFKVPVRDV
                     YPAYKFYCQDSGYKPLARNSFTQRMNELNFENKNAKMGGKTVRCWIGFRIKGEF"
BASE COUNT         6680 a         4241 c         5140 g         6771 t
ORIGIN      
        1 atgccgcata aaaaagaaaa tatgctgaaa aataacgaaa atattagaaa ttctttcatc
       61 aattgacgga aacggcatta agaaaaccat cgttttctga aaaacaatgg tttcgtttgc
      121 tttcacaaga aaagctcttc tagttttctg gcgaccccgt cctcttcgtt agagtaagct
      181 agctgctggt cggcaaaggg cagcagcaca gggctggcat ttttcatggc atagccggtt
      241 ccggcaaagg ccagcatttc tgtgtcgtta tgctcatcac caaaggcgat taaatcctta
      301 ggctccttgt tgtaaatgct aagcaggtat tttaaggtat aggccttatt aatgtttttg
      361 ggggacatct caaggatatt taagggacca ccccaagagt ccacctcaat ttcgtccttg
      421 aagaaggcgc gcatggcctt ggctagggca tacttatcct catgatgcgt ttgcatgaga
      481 agagcatttg gatcctgcgt gattttgtcg atctgtaaag ccatatctgg tgtgatggcc
      541 tcaaaccaaa aaggttgggg tcaatgctct caggcctatt catggtaatg tagaaggctt
      601 ttcggtactc actagcaata aagtccatct ggaagtcctc ctgcactgct aggagtttga
      661 gaaggtatgc cttatcaaga gtcacattat gctcgtattt ccatctttgc tcaggtaggt
      721 gggtcaaaga gccattaaag ctaatcatag gtgtctttag ctctagctga aggtagtagt
      781 caatagccat acgataagga cgtcctgtcg agatgatgac ctcatgtccc ttagcttgga
      841 cggccttaat ggttttttga gtataggtag agatggtatt gtcgtgatgc aataaagtcc
      901 cgtctaaatc aatagcaatt agttttttag tcatacacta gattataaca aattttagga
      961 tcagtggaag agaaaattgc tgcttggacg gttaatagaa aaaaaggctg ttaaattttg
     1021 aacgatcatg gcaaataaac gaaaaaagct attgaaaata gaacgataaa atgttacgat
     1081 gaatatatcg ttcgtaaaaa cgataataat catttggttt taagagaaaa agcttatctg
     1141 atgagataag ggcttttttg attttgccta tcaataagga gactccattc aaatggaaaa
     1201 gttttttaag ttaaaagaaa atggcacgac ggtttcaaca gagctgatgg ctggtgtgac
     1261 gacttttttt gcgatgtcat atatcttatt tgttaaccca agtattttga gtgcagcggg
     1321 tatgccgtcg caagcggtgt ttttagcgac catcatcgca gctgctatct ctaccttgat
     1381 catgggtttg tttgctaatg tgccttacgc attggctcct ggtatgggac ttaatgcttt
     1441 ctttacttac actgttgttt ttagcttagg attttcttgg caggaggcct tggctattgt
     1501 ctttctttgt ggtctgttta atatctttat cactgtcaca aagcttcgca agagcattat
     1561 caaggctatt ccagtaagcc tgcagcatgc tattggcgga ggtattggag tctttgttgc
     1621 ttatctaggt tttaaaaatg ctaacctgat caccttttcg ctatcatctg ctgagattgt
     1681 tactgtaaat ggtgttgagc cagctaaggc aactgctgaa acatttgcta atggcgtctt
     1741 ctctgttaat gctaatggtg gtgtggttcc agctatttca accttcaccg atccgagtgt
     1801 tttgctagca gtttttggtc tgctgctaac agcagtgctt gtgcttaaga acgttcgtgg
     1861 agccatccta attggtatta cagttacaac tttagccggt attcctattg gagtggttga
     1921 tctttctgct gttaattttg cagacaatca catcagctca gcctttgctg aattagggac
     1981 aacattcttg gctgcctttg gtggcatggc gtcactgttt agtgattcaa gtcgcttgcc
     2041 gcttgtttta atgacgatct ttgcctttag tctatctgat acctttgata cgattggaac
     2101 ttttgttggg actggtcgtc gaacagggat tttctctgag gaggatgaga gagctttgga
     2161 aaacagctct ggctttagct caaaaatgga ccgtgcgctc tttgctgacg ctattggtac
     2221 ttcaatcgga gctttatttg gcacctcaaa taccacaacc tacgttgagt ctgctgctgg
     2281 tattgcagag ggaggacgta caggtctaac agctgtatca actgctgtct gctttgtctt
     2341 atctgtttta ctgctgccga tcgtgggaat tgttccagcc gctgcgactg caccagcctt
     2401 aatcattgtc ggggttatga tggtatcgtc cttccttgat gttgattgga gcgactttga
     2461 cgttgcccta ccgtccttct ttgctgcttt ctttatggca ctttgctact ctatttcata
     2521 cggtgtggct ggctccttta ttttctattg cttggtgaag cttgtgaagg gcaaaaccaa
     2581 ggagattcac ccgattcttt ggggagcaac cttcttattt gttttgaatt ttatcatttt
     2641 agcgttattg taaacgacta atgaggtact taggtgcctc ttttttgctg ggacaataaa
     2701 gacagggatt accgtttgga ctgggactat ggactttcta agctcatagg cattgccacc
     2761 ttttcctagt cctatattta ggctaagtct taaggtttta gagctgcggg ttgatttcta
     2821 gagcattcag ccctggctat cacagcagaa tgccatgatg ttaggtccat gtgatttgct
     2881 gctggctctt ttgatttatg agatgttaaa gctgattgag ctttgacgac attatatgag
     2941 gactgacgag cctagaatat tttgctgaca ggctggctta ggcttggaag accgtttttt
     3001 ttctgttata atagccttat gttttatagc aaaaatgaga atgaattaat cgcttacggg
     3061 caaggcattg gtagacagct aaaggcagga gatgtgcttg tcttgactgg tgacttaggt
     3121 gctggtaaaa caacgctgac caagggggtt gctaagggtt tggggattga tcagatgatt
     3181 aaaagcccaa cctatactat cgctcgagaa tatgagggaa gactaccctt gtatcattta
     3241 gatgtttatc ggattggtga tgatccggac tctattgatt tagatgattt tatctttggt
     3301 ggtggggtta ctgtgattga gtggggcgag cttttagcca agggaaccct gcatgactac
     3361 cttgaaattt taataacaaa aacagaaaca ggccggcagg ttgattatct agcacatggt
     3421 catcgatcag aggcacttct tgaggagctt aagcatgtct gagcaggtgg tgacaatcga
     3481 agaggccaag gcctcagatg cgtcagcttt gatcactcta attaaagaag ctgctgatga
     3541 gacagatttt atcacaggga ctgaggacgt catagctgct accgtagagg tgcttgagtg
     3601 ttttctagag gctagtcagg agtctttgac agatatttgc cttttgctaa aggtgggaga
     3661 tatattagct ggtctgctaa atatagctgg caaagcatat cgtgagacta gctatgttgg
     3721 cgattgcttt atgctggtct tgaaacccta ccgcaatcat ggcctaggac agcttttgat
     3781 ggagactacc cttgattggg ccagagaaac aaagcagctt tgtgctttgg agctggaggt
     3841 tcaggctcga aatacttgtg cctatcatat ttatgagaaa tatggcttta aaatagaggg
     3901 cgtcaaaaga aaggacgtca aatcaagaaa tggagactat caggatgttt accttatgcg
     3961 taaatatctg gaacgtgaat agatgaaaat tggaaaaaaa atctttttaa tgctgacagc
     4021 tattgtgctg ttgaccttgg gggctatggg agtttaccta accaatgcct ataccttttc
     4081 aactggagaa ttgtcaaaga cctttaagga ttttgcaacg tcctccaaaa aaagtgatgc
     4141 cattcaacag acagagccct tttcaattct attgatggga gttgacacag gatcgtctca
     4201 cagaacctct acctggcaag gaaatagtga ttctatgatt ctggttacga ttaaccctaa
     4261 gaccaaaaag acaaccatga caagcttaga aagagacatt ctcatcactt tgtcaggtcc
     4321 aaatgataat gagatgaatg gagcagaagc taagctgaat gctgcttatg cagctggtgg
     4381 tgcccaaatg gctatcatga ccgttcagga cttgctgaat atcacgattg acaaatacgt
     4441 tcagattaac atgcaagggc tcattgattt ggttaatgct gttggtggca ttactgttac
     4501 caatgaattt gactttccta tctctattgc agataatgag cctgagtatc aggctaccgt
     4561 tgcaccagga actcacaaga taaatggaga gcaggccttg gtctatgctc gaatgcgcta
     4621 tgatgatcca gagggagact acggtcggca gaagcgtcag cgcgaggtta ttcaaaaggt
     4681 gctgaaaaag attcttgccc ttaacagtat cagctcctac cgaaagatct tgtcagctgt
     4741 tagtggtaat atgcaaacca acattgaaat atcatcacga accattccta atcttttagg
     4801 ctatacagac gcccttaaaa atatcaaaac ctatcagcta aagggtgagg gagcgacctt
     4861 gtcagatggc ggctcctatc aaattgtgac ctcagatcat cttttagaaa tccaaaatcg
     4921 cattcgtgct gaattaggcc ttgaaaagct tagtcagcta aaaacgactg ccacagttta
     4981 cgaaaacctt tatggctcgt taaaaactca gtctactcag gatagcagct attattacaa
     5041 ttcaggtagc ctaccggcct atacagactc atctacccag tactcaacct attcctcaga
     5101 gacgtcctct agcagcagct atcaggacac aacagctggt acacaagagt caggagcagc
     5161 taatgtgact cctagccctc aagcagactc accagcagag cagcaatcaa gtggtgcaac
     5221 cactggtacg ccagcagcgc cttagggtac agccaaaaaa acgaagaaat ctcatcaagg
     5281 cttgatcctg tgagtgattt cttcgtcttt tttgtacata caaaaagagc ccataatccc
     5341 tatagcggac ttgtccacta cagaaacgat agagcccttt tttgtcacct tgaggcttgg
     5401 tagtctgctt aggcttatgg ggtttcctgc tggtacttgc tcatacgttg ttggatttca
     5461 gtcagatggg cctgagcttc ttggttaaag gcctgccatt tgtaggctaa ttctgttcct
     5521 gctgcttgaa gcgttcgagc ctccttttga atgatggcga gatttgcctt aatcctatca
     5581 acatcggcct ggatagcctt cttagaggtt tgcatggcta ctagagtttc tttgatttga
     5641 tgacgtttac gatacacttg gtaggctaaa acggatgtga gaccaattgt ggtcattgtt
     5701 tttagagtca ttggctaatc tcctgactaa tttgttgtgc caaggctgct agggctggga
     5761 agtcaggctc atgtgttgta tactgaatag cgatcccgtc ttcttggctg tagcgaggaa
     5821 cgaggtgcac atgcgcgtga aaaacagtct gaccagctag ctcttcatta ttattaataa
     5881 tgttcattgc agtagcacct gttgcttttt gaatggcgcg agcgatttta ggtaatcgtt
     5941 caaaggtctg gctagctgtc tcggcgtcca ttgctaggat atttcggaca tgctttttag
     6001 gaatcaagag ggtatgaccc gctgttgttt gcgaaatatc caaaaaagcg agtacctgct
     6061 catcctcata aaccttggag gagggaatct caccgctaat aatgctgcaa aagatacaat
     6121 tttccatgtg ataatccttt cgtctgcgta gcaatggctc aaatcagtag ttgaataatt
     6181 ttagaataag aaatcagtag ttgctcagtg accatagcta tctcatacta tagttatctt
     6241 agcatgtact ggtctatatt gcaattgttt atagctggtg ctaatggtta tcgaccacat
     6301 gactagcaaa gccttttgaa tcatgataat ggactaagca attatggtta agcacataac
     6361 taagcctgct acttgctgca agctaggtcc gtcaaaggtg tgcatttgcg cactatcgta
     6421 cggtagtgac atggcacaat atttgtaagg acaagagttt cagagagtat gaggtgctgg
     6481 aacttcttga cagttaaggc tgagaaagct tttagaacaa aaaaagattg aagcgtcagc
     6541 aacataggcc ttatcttcaa tcgagtgcgg atggctttac tacaggctag ggtcctcgtt
     6601 ttgcgagaat ttatcaggaa cagcccatag gctagggtcc tcattttgtg agaatttatc
     6661 aggaacggcc cataggctag ggtcctcgtt ttgtgagaat ttatcaggaa cggcccatag
     6721 gctagggtcc tcgttttgtg agaatttatc aggaacagcc cataggctag ggtcttcgtt
     6781 ttgtgagaat ttatcaggaa cagactcttg agcttcttca gagctgacct gccattcgtt
     6841 agccgtgctt acttcctgag gcttttcaga gatagtttgc cagccatctg tgataaccac
     6901 ctcctgtggc ttttcaaaga tagtctgcca ttcgttagcc ttagcctctg tttggactag
     6961 gcctgaaatt gaaagtgctg aaagtgatac caaaccaaat gttaaaaagc gtgacaaatt
     7021 cataacatac ctcctttgtc attaaagacg caacacttat ttacatgtta acgataacat
     7081 tatattatta aaaattcaat acaataagat aatattatca tgatttttta gatgacgcct
     7141 tagatgagct gctatttagg atcaccaggt cattcgaata tgatgtgata gatggttagg
     7201 actgatagat caagctaata tagcctctgt ttttatagct aggccttttt cttgatgatc
     7261 ttaaaataga cttcagattc actcagcgtt tttagctgat gggagcattg atcaaaacag
     7321 ttaacgctct gtgcagaaat ttgttataat agctaatata agtgtaccct tagtattagc
     7381 tgccccagct ttcttaagta gggtcaagct aattggtctt atcagtgctt caaagcgctg
     7441 gataggctga tgatgacaaa gcattgccta gtaagtccta tctgtctagg ctaataacct
     7501 gtcatctagg gaagctagta tgcaaagcta caatagatta gatattagaa agaaatgata
     7561 tgttaaacat tgagaatgtc actggaggct accttaatat tccagttttg aaggatatta
     7621 gcttttctgt cggaaatgga gagctagtag ggcttattgg tctaaatggt gctggtaagt
     7681 caacaacgat taatgaaatt attgggtttt taaagccata taagggaagg atttccattg
     7741 atggcttaac cttggcggag catgaagctg attatcgcaa gaaaattggc tttatcccag
     7801 aaacaccaag cctgtatgag gagctgacct tagcagagca tatcaatacg gtagctatgg
     7861 cctatgatat tgatgtggag ctggcacata agcgagctga gcccttctta gagctgtttc
     7921 gtttgacgga taagctggat tggtttccgg tgcatttttc taagggaatg aagcaaaagg
     7981 ttatgattat ttgcgctttt gtcattgacc ctagtctttt tattcttgat gagccctttt
     8041 tggggcttga ccccttagca attgctgatt tgattaaggc tttagaggtt gaaaaggcaa
     8101 agggcaagtc aattctaatg agtacccatg tgctggattc ggcagaaaaa atgtgtgacc
     8161 gttttgtgat attgcatcag ggacaggtgc gtgcacaagg gactctggcg gatttgcagg
     8221 cagtctttgg agatgcttca gctagtctta atgacattta cctagcgctg acaaaagagg
     8281 ggtaagctat gaaggcatta tttcgtaagc gtcgtcagga gtttcagcac aagcatacca
     8341 agtatctgcc ttatgtcttt aatgatcatt ttgttcttgt cttgctgttt cttttgggct
     8401 ttattctttt tcagtacagt caactactca agcattttcc tgctaatcct ctaccgattc
     8461 agctaggttt gttgattgct gtcttgtttt tgcttaatct ggggtcagtt gctacctatc
     8521 ttgaaaaggc tgatcagcat tttttgctga ccaaggaggc agaggttatt gcccatatca
     8581 ggtcagcaga gcgcttgtcc tttattcttt ggtctagcct tcaaacggtc ttgctgttac
     8641 ctttatttcc tttgtttcaa aggcttggtg tttccttgct tgcctttgtg ctattgcttg
     8701 gtgttttggt gctggctaag cgcttactgt taaagcgtaa ggtggcaagc tttttgagct
     8761 ccaaggggct tgattgggaa aaagcgattg cttttgaggc agatcgccag caggccattt
     8821 taaagtttta tgctttgttt acaaatgtta aaggaatctc aaccaaggtt aaggaaaggc
     8881 cttacttgaa tcctatactt aagcttatca aggcagatag taaaaaggtt tggacaaacc
     8941 tatatttaag agcattttta cgcagctctg attatctagg gttatggtta cgtctgttgt
     9001 tgcttagttg cttgtcactt gcctttattt ccaaccctta tttagcagta ggcttggcct
     9061 tggtctttca ttatctaagt ctttttcagt tattatcact ttatcatcat tatgattacc
     9121 attatatgag tgggctttac ccgactaaac cacagcataa gcaaaggaat ctactttctt
     9181 tgttgaggca attaagtggt ttgatgctta tcgtcaatct tgtgctctgc cgttcttggc
     9241 aaaatgctct tgtgttgatt gtggcgatgg gattattaaa tcttctttac ttaccgtaca
     9301 agttaaagaa gatgattgac taagtccttt aaaacaagta aaatagggat aactggttac
     9361 agaagataga aaaggagggg ataaggtgac aacaaccgaa caggatcttg tattgactcc
     9421 cttgcgcgga aaaagtggca aagcctacaa agggacctat ccaaatggcg aaagcgtctt
     9481 tatcaagctt aatacaacac caatcctacc tgccttagca aaggaacaga ttgccccaca
     9541 attgctttgg gcaaagcgta tggggaatgg cgatatgatg agtgctcaag agtggctcaa
     9601 tggtcgtact ctgactagag aggatatgaa cagtaagcaa atcgtccata ttctgctgcg
     9661 cctccacaag tccaagcagt tggttaatca attgcttcag ctcaactata aaattgaaaa
     9721 tccttatgac cttttagtag actttgagca aaatgcacct ttgcaaattc aacagaattc
     9781 ttatttacag gctatcgtca aggagctaaa gcgcagccta cctgaatttc gctctgaggt
     9841 ggccacgatt gtacatggtg atatcaagca tagcaactgg gtgattacca ccagtggcat
     9901 gatttttttg gtggactggg attgtgtgcg cctaacagat cgaatgtatg atgtggctta
     9961 tttgctaagc cactatattc ctcggtcgcg atgggcagac tggctatcct attatggcta
    10021 taaaaataat gataaggtca tgcaaaagat tatttggtat gctcaattct cttatctaac
    10081 tcagatttta aggtgctttg ataagagaga tatggagcat gtcaatcaag agatttacgc
    10141 tcttagaaaa tttagagaaa tgtttagaaa gaaataatgc gagttagaaa acgaaagggt
    10201 gcgcaggagc acttggaaaa caatcctcac tatgtcattt tagagccgga ggctgctaag
    10261 gggcgctggt gtgaggtctt tggtaatgat catccgatcc atattgaggt tggctcaggc
    10321 aagggagcct ttatcacagg tatggcgttg aaaaacccag agatcaacta tattggcatt
    10381 gacattcagc tatcagtgct aagctatgct ttagataagg tcctagcctc tcaggctcct
    10441 aatgttaggc tcttgcgggt tgatgggtca agcctgacca attatttcga tgccggtgag
    10501 gttgatatga tgtatttgaa tttttcagat ccttggccca aaagcaggca tgaaaagcgt
    10561 cgactaacct acaaatcctt tttagacact tataagcaga ttttgccgga aaatggtgaa
    10621 attcatttta aaacagataa tcgtggctta tttgagtata gcctagcgag cttttcacag
    10681 tacggtatga ccctcaagca ggtctggctg gatttacatg ctagtgatta tcaaggaaat
    10741 gtgatgactg agtatgaggc tagatttgct aaaaagggac agattattta ccgcctagaa
    10801 gcaacattct agtagctatt ttgacaaaaa tatgatacac tactgaggtt gagttgatca
    10861 gccttttact tggagaggtc gcatagtggc cgagtgcgca cgcttggaaa gcgtgtagtc
    10921 cttaacgggg ctcgggggtt cgaatcccct cctctccttt tatcctattg atatatcaag
    10981 gggttcggtg gtttcacccg ttttttaccc gtcaattttg agattttgaa aaatgttttt
    11041 gacctgatgg tcattttttt cttttagact ttctatctga tgagcgtaaa ccttgagtgt
    11101 gatgttgagg ttttcgtgac ccagcagctt ggatactgat attagatcaa cgccctgcgc
    11161 tatcaaataa gaagcgtaag tatgtcttag cgagtgattg gttagatttc tgccggtcac
    11221 tctttttata actttgttcg ttgcattgtt tgacgctccg aaacagatac gacttagttt
    11281 attatcttga taatgattat ctttaaaata ttttaataat tccacactat tgttatcaat
    11341 agggaccttc ctgatggatt gctcgttttt tgtaggcctg aaattttgag aaatcgagta
    11401 atcaaaagtt ttattaacat cgacatagcc attgtcaaaa tcaatatctt tccatgtcaa
    11461 cccttgagct tctgcaaatc gtaaacctgt tatagctatg atatatgtcg taaggtatga
    11521 tgggtacttg attttttcct tagcagtctt gataaaagca aggtattcag attcctccat
    11581 aaatttttcc gattcttctt tggcgggttt ttgcgaccta acgatggctt catcggcaaa
    11641 attatcccta ataatgccgt cacgaatggc cattttacaa gcacccttga tttgataatg
    11701 aaatttatcc agagtttgtt gggctacttt ttcgccaaag tcattaagga cttgctgata
    11761 aaaggtgtgt gtgatactct tgagcttccg agtcccgaaa taatgttcga tgtgcttaaa
    11821 gttcttagta tatgtctgcc acgtctttgc ggtaatgtga ggtcttttat atatgtctgc
    11881 ccaacgcttg ttgtagtcta aaacagtaat atctaaaagg tctgccgtca gcgtgtttaa
    11941 atcagtttct gcttgctggg cggcaacttt tgcaagtgtt tttgttttaa atccacgttt
    12001 tgatttttct ctttttttac cttgactgtc acgataggtg atgcgatact cccacccgga
    12061 atctaatttt cgataaaatg ccattgtttt cacctcattt ttctgttaaa atgggtacaa
    12121 gaaaacgagc catttaatgc ttttttcttg tatggttttg cctttcacac aaactttggt
    12181 cggggagtgt gagaggcttt ttttatttaa agaaattatt aacatttacg tactgagcct
    12241 gcgtaagctt agtttttaag gttttaactt ctccggtttg tatatttctt aaggctaccg
    12301 ttgcttttcc aggtatttct tcagaagtgg ttgtggcagt agtgttaatg gttccttttt
    12361 tctttctagc cccaccagtc attccaccga caatggttcc aacgcctggt gccaaaactg
    12421 tacctattgc tgcccctcct agaacactac cagaacgccc tctttgagta gttttccctt
    12481 ttgttactgt tttttcaata attcgtgaac catcaaattg aaggttaaca aactcataaa
    12541 gctcaggagt ttcagaataa aaaccaatat aatattttcc atctatggtt tttcgtatgg
    12601 ccgttggtgt tcctagtcct aaatttaggg cagggggtag tatcattttg ctttcttgtg
    12661 aggctttttt tcttagttcg ttagctttaa ttgcaccatc tttagctttc ccggcagctg
    12721 ctatggcaaa tccttttaat ttagttatat ccatgcttat ctccttaact aattaaaaac
    12781 tctaattctt ccttgaccat cacttcgtca gcgattgagg tcagttcata tttttccatg
    12841 aattggatgt agttgaaatc ctccatatta tcccaatacg atagctcttc ttttaagaga
    12901 tggtgtatca tacatctatc tgcttgtagc tctgcttttt ctttgtttag tttgtaataa
    12961 ctcgcagtat gttctctgtg tcctagttca tgatagatga ctttgtgttt atatataccg
    13021 tcaagataag tgtcaatcgc aatgacgttg tgttttttat taaacattcc gggggtgttt
    13081 gtacccctac cgtcaaagta tactaaatcg attccttttt cctgacagac tgtttctggt
    13141 gtcatcatag agcagtcctc tctattttct atttttgatg cgcgtttcca atatagatgt
    13201 gataagatct atatcctcgt cgttgagttc gtggccatcg aagaagaaag tttcttctgc
    13261 atcttttttc agatcaattg cgacagaagc gtgcccatct tgagcaatct taggattatc
    13321 tgtcctgcca agtaaatagt cggtagaaac attaaagtag ttagctattt tttctattgg
    13381 gtctgtatta gccgtttttt tactttttaa attataaata tagttttcgc tcaaccctat
    13441 atcagttgcg accttttgga gagatactcc tcttttttta gctaaggctt caattcttga
    13501 atacacctca aacattgtca tatcaacctt tctgaaagta tgacaaaaaa tatttaactt
    13561 tttcgagtaa aaattattga cttagttcac acgatagagt aaaatagttt ttgtaagata
    13621 gttagttagt aaaaaacgaa gttaaacttt ttacaaatct ttttaaagta gttggggaac
    13681 tgcgcaatat aaaagagtta taaaggttat aactaggttt ttcttatgcc ttcattttac
    13741 attaacgtgt aaaataagtc aacacaaaaa tgttattttt ttactaactt tcttacttac
    13801 aaaaataaaa caccacctag ctgctatcta gatggtgcta cggaaattat tctgctcaaa
    13861 ctaatagcag tagtcaacaa cacttcaccg gtatcgtccc cggcactgta gttggagtag
    13921 aaaatgattc tcgattttga tttcctattc ttcgtcgctt ttgcgagcga cagccagttt
    13981 gcaatttctg tggtcgtccg gccaggacgc caatgaagat ataggaaccc ctattgaatc
    14041 ttgctagtca agtgcggtag gcaaaaggaa aacctacaaa cgaatccatc ttctactgag
    14101 acacagtctc cttcaaaaac tcggacaaat gatacgtcct cctttcatac aaagggtatt
    14161 tacattatat atttgtaagt cgaaaaaatc aagatggata ctgtttgaat cgagcagaat
    14221 aacgtttccg ttaagttgtt ttaaataaat ctacttacta gaaaggagtc taacgcatgt
    14281 cagacaacac ggtcgctgtt gaaaaaatta agaagtatct gcttgacaat aagctaaaac
    14341 aagttgactt agcagttacc tataataaag aaccgcaaga tgtggcgaat atcttagctg
    14401 gaagaaaaaa agatccagca tcaaatcgtt ttgtcttgaa agttatttca gatttgaaaa
    14461 ttagatagaa gagaattata tgaaccaatt gcttaacgca atactagaaa ggaaccttat
    14521 gacagacgca gaaaaacaaa actatgatgc ccttttcatt aatatttttg aacgtttaga
    14581 aaaactggag gaaggctatg attttagctc cgtagctaca actacggggg tccaaaatag
    14641 cggcggtgtt caatatcgtg aatgccaaga agacggaact gtagtcaaaa cagtatccaa
    14701 gaggagctta ggctactgat gattatatca aaaaagtccg acgggaatcg ggctcaacaa
    14761 taatacttat gaggtaattt tatcatggat agcagattat tacaaatgct agatgagttt
    14821 gaagcaggcc ttattgatcg caaggtcaaa gtcatgaaaa tgattaacaa tgaaacggaa
    14881 acttatccgc tagaactcaa taaaaagcaa gtcagtaaaa tgtttgggat tgaccctaaa
    14941 acatttgacg caagatttaa cagccacaaa gatttcccac gtatcgaaac gggaggtcgg
    15001 gaaaaatatc cacgagactt ggtcattgag tggtatcaca gaaattggag tataacatga
    15061 acaaactaga attattttta ttagcgacaa caatcgtctt agcaatcatc gctagggtgc
    15121 aatatgaaat tattaaaaaa cataactcac ccgagaataa gcgaaaaatt tttagggaag
    15181 tagctttaga aaacagcaag aaatggagtg cagaacgtta tgtctaaatg ggaattacaa
    15241 aaacaactac tggaaaatgc gacagatttt gagagcacag ttgaggcttt acttgactta
    15301 aacgagtctg gcgaaatatc tgatctggaa ctcttactga acttaaagga taaattcaga
    15361 agctattcca aagaaaaaat acgtatcctt aatgaaattc tcaagctagg aggtgcagaa
    15421 tgatgacaac ttttgaaaag attattaaga aaattaatcg gattgagggg gagttagtta
    15481 aacctgaagc tgaaagacga gatagcttac ctatcctatc tgctcagttg ggttctatta
    15541 aacaagattt aaaattgatg ctttggattg agctgccttc gttaaataat gtggagaaat
    15601 acgaagctct ttatcaagga aatgatttta aattcagtga aactttctta gagcgtcaag
    15661 cgacaagaaa agccttttgg agacgattag ctaaggaaac ttttaaagaa gaccaggata
    15721 ggaggaactt tgttaagttg gctgagaaag aatttaaagg tgcaactttg tcatggcaag
    15781 aatttttgtg gggtaaaaag aaatgaatat ttcaataaaa ctcataggtg aaaccctagc
    15841 tggtttaaat gatattttac gccagggggg gctctcttgc tcccaaaacc aagccttagc
    15901 agacgcagtt tttatattaa cagctttaaa acaagtaatt gaggagagaa aatgaactat
    15961 ttagaatatg cactagttta tcttgaacgt gagttagaaa ttattgataa cgaagttatc
    16021 gaagttgagt tgccgggcgg ggattgggag tttgtgccta atccctacta cgagaaaggt
    16081 ctacatgata gcccacacta tcgtagtcag gttgctaaag acattcttga tattaaagga
    16141 cttttgggga ggtgaggcta ttgattgcat caaaaaagac ggcttaggaa accgtcaaca
    16201 attatacaca cttaaattat aacacagaaa gagagaaaca caatgattga agtaactttt
    16261 aaagcagaga gcatggcagg tgttttcgat gctatgcgtg aagctctgga tatgccgaag
    16321 acagtaacca aggatgttgt tgaagaaaaa ccagctccta aaaagaaaga agagtctgta
    16381 actttgacat tagctgatat taagaaaatg gctaaagcca aggttgaaga agggaagtca
    16441 aaggacatca aggaagtctt gaaagagatg aacgtcgcaa aagttggtga acttgaagaa
    16501 taccagtttg cggagtttgt tgagaagttg gaggctctct aatgccagta gaaaatcacg
    16561 cactactgtc tgcttctagt gctcacagat ggctctattg ccctatgtta cctagactgg
    16621 aagcagacta tcctagccgc gacaccgtat acactcaaga gggcacaagc gcccacgagc
    16681 tttctgaaat caaactgatg tacaagtctg gtaaaatcac caagcgtaaa tttaacacgt
    16741 taaccaagac ttttaaggaa aactcagact tctacaacga agagatggaa gagatgacgg
    16801 agctttacac agatattgtt atggagcacc taaatgctta tgagaacgcc gaaattgaac
    16861 ttgaaaaacg ggttgatttt agcgactggg tgcctggcgg ttttgggact tcggatgtcg
    16921 tcattttggc ggatggagtc attgaaatta ttgatcttaa gtatggtaag ggcatgcctg
    16981 tgtctgctaa tcaaaacccg cagatgggac tgtacgctct aggagcttat gcttcctacg
    17041 atatggtcta tgactttgac cgtatcaaga tgactatcat tcagccgcgt ttagattcgg
    17101 ttagttctgt tgacatttac gtggaggagt tactctactg ggcggataat gttgtcttgc
    17161 ctatggccgc tcaagcagac gcaggcattg gtgactggaa cctaagtgaa aaagtattgc
    17221 agtggtctcc tgtcgcagct aaattggtac caagagcgca agaaaattgg gaattaattg
    17281 ataaatatga ctatcaggag cctgtctatt tatctgatga agccgtcgca gagatccttg
    17341 acaaagcctc agctatcaag aagtgggttg agtcagttga agcctatgcc ttgaaagaag
    17401 cactctcagg aaaagaagtt ccaggctata agattgtcga aggtagaagt aatcgagtta
    17461 tcactgataa agacaaagca attgatattt tacaagataa cggctttgac gatgagattt
    17521 ttaaaccgaa agagctgtta gcaatgggag cccttgaaaa gttaataggt aaaaccactt
    17581 ttgctgattt attagcagaa gtaattgata aaccacaggg caaacctgta cttgtccctg
    17641 aaaaggataa gcgcccagca ataaacagtt tagaacaagc aattaaagat tttgaatagg
    17701 agaaaaataa ttatgacaac aacaccaaac acaactaaag tagtgaccgg aaaagtacgc
    17761 ctaagctatg tagctttact agagcctaaa gcctttgaag gccaagaggc taagtattca
    17821 acagttatct taattccaaa aacagacaaa gtcacaatca agaaaattaa agacgcgcag
    17881 aaagctgctt atgaggctgc caaggacaat aaactcaaag gggttaaatg ggagcgcgtt
    17941 aagacaacgc ttcgtgacgg cgacgaagaa atggataccg aagagcaccc agagtacgct
    18001 ggacacgtgt tcatgtcagt gtcaagtaaa actaagccac aaatcattga caagtataaa
    18061 aaccccgttg actcagcgga tgaagtttac tctggcgtct atgctcgcgt atcacttaat
    18121 gcctatgctt acaacacagc gggaaataaa ggaatctctt gcggattaaa caacgtccaa
    18181 attgttgcta aaggagacta ccttggcggc cgttcgtcag ctgatgcaga ttttgacgag
    18241 tggaacgaag aagaggacga agacgatatt ttatagtaga gagcctcttt agaggctcct
    18301 catttttaaa ggagaggtat gagacattta aatattgata ttgaaaccta tagttcgaat
    18361 gacatcaaaa atggggttta caagtacgct gacgctgaag attttgagat tttacttttc
    18421 gcttactcta tagatggcgg agaagtagag tgccttgatt tgacaaggca gtctctacct
    18481 gaagacatca aagatatgtt atttgatgat aaagtccgaa agcacgcctt taatgcccaa
    18541 ttcgaaagag tttgtctcag tcgttacctc ggcctacctt actatctaga tccttgccaa
    18601 tggcaatgca ccatggtgct ggcccaagag ttgggtctgc cttcaagctt ggaaaagtgt
    18661 gcgctgtatt taaaattagc acaggaaaaa gatacctcgg gtaaaaactt aatcagatac
    18721 ttttccctgc cttgcaaacc aagtaaaact aacggtggga gaactagaaa tttaccagaa
    18781 cacgcccccg aaaagtggca aatgtttatt gactactgta tccaagacgt tgttgttgag
    18841 atggcaatcg ccgaaaaact agaatcagtt cctgtgcacg accgcgaatg ggactactac
    18901 gcctgcgacc agagaatcaa cgacagaggc gtggcacttg ataaagagtt agttgcttcg
    18961 gctttgtatt gtaaagatgt taagatggaa agtttgtctg gtgagctaaa agccataaca
    19021 ggacttgcta acccaaacag tagagctcag ttgctaccgt ggctaaaaga acacggttat
    19081 tcggctaacg ggctgactaa agcagatgtt gaacaggaac ttaagacggc tgaaggagaa
    19141 cttaagagag tcttagaact taaactacaa accgctatgt caagtctaaa aaaatatgaa
    19201 gctatggaaa gagctatgtg ctcagacgga cgagttcatg ggctacttca gttttacggg
    19261 gctagccgga caggaagatg ggcgggcaga gttgtccaag tacagaattt agctaggaat
    19321 tatataaagg atctagatga tgccagggag tatgttaaaa agcgtgacat tgatgctgtg
    19381 gagattttat acgatagcct taatgacact ctaaagcagc tcgtgcgaac cgctctcgtg
    19441 gctaaagatg gctgtacctt ctatgtctct gacttctcag cgattgaggc tagggtgatt
    19501 gcatggtttg ctggagagca gtggaggctt gacgtgtttt cgacgcacgg gaaaatctac
    19561 gaggcgtctg ccagtcagat gttcggaatt ccaattgagg agattgacaa ggaactacgc
    19621 caaaagggca aaatttcaga gttagcactt ggctatcaag gaggtcctgg agcgcttaag
    19681 cagatggggg ctctaaatat gggagtcaag gaagaggagc ttcaagggtt agttgatgac
    19741 tggcgcaggg ccaataagaa aatcgtccaa ttttggaaag acgtacaaag agccgccatc
    19801 aaagccatca aatcgagagc accgataaaa cttggaaaac tacgatttag ataccggaaa
    19861 ggtttcctct ttataacatt gcctagcggt aggaacttag cttatgcaag agccaaggtt
    19921 gagccaggcg actatggaga caaaatcatc tatgagggcc aaggagataa ggcctacttc
    19981 acagcgcaag agacttatgg cggtaagctt gtcgaaaata tcgttcaggc gacggctagg
    20041 gatattctag ccgaagcgct tctgagaatt gaagctgcag gctatggtgt tgttttccac
    20101 gttcatgatg aggctattat cgaaggctca ggcctgacaa tcgaagaggt taatgatttg
    20161 atggctcagg ctcctgaatg ggcggagggt cttcctttaa atagcgaagg ctatgtaaca
    20221 aagtattata tgaaggatta gatagatgaa gcaagaaaaa ctaatagtaa agtcttctcc
    20281 cctgcaagag cttcatatcg caacaggtag ttcgcgaaca gctaagacat ggaaaaatat
    20341 cacgctaact tggcaggagc tggttgagag gttagagaaa cctacagtca cccaagagac
    20401 gtttgcggag taccagaaga tgtctcgagc agaaaaaggg caagcaaaag acgtaggggg
    20461 ctttgtcggt ggatggctaa agcaaggtaa gcggaaaaat gaaaacgttc aaagtaggtc
    20521 cttggttgcg cttgacgcag atagcccaag taaagatttc ttagataggc tagacctgct
    20581 tgcggattat gcctacgtac tctacagtac tcacagccac tcaaaaaaag ctgctaagta
    20641 ccgtcttatt atccctactg accgtttaat gatgcctgat gaatatgagc cagtcgctag
    20701 atatttggct aaccaactag gcatgtcaaa ctttgatgac acgacttatc aaagcgtgcg
    20761 cttgatgttc tggccgagtc actcaagaga tgcagacttt acgtttaaat ataacgacga
    20821 ggcttttctg agtgttgatg aggtgcttga tacatacccg gactggcatg actcaagctt
    20881 ctggccagaa agcccgacgc acgctgttaa aagacagcgt gaagctaaaa aacaaggtga
    20941 cccgcttagt aaaaaaggac ttattggagc cttttgtcgt aactatgaca ttagacaggc
    21001 cattgcaaca ttcttacctg aggtttatga agaaggaacg actcctgata ggtacaccta
    21061 cactgatggc tcaaccgcaa acggcttagt tatctatgat gatgtcttcg cttatagcca
    21121 tcacgggaca gatcccgtgg gggatacgct tgtaaatgca tacgaccttg ttcgtatcca
    21181 taaattcgga gagcaagata gcgaggctaa agataatact cctactaata agctaccatc
    21241 aagcaaagcg atgaatgctt ttgtctgtga cttacccgaa attaaagatt atctaatggc
    21301 ggaggcttta ggcgatttcg atgaagagtt accagtcgaa gatgacagaa gctggcttga
    21361 aattgatgag aggggcgaac cggaggtcaa tagttatttg ctagcaacgc agattattaa
    21421 ggaggttccg atttattggg atggcttaga atttttacgc tacgacgcta aaaaaggcat
    21481 ctggttgcca aacgctgagg aatatttgaa gagttatatc tcaactaaga aactcggtaa
    21541 aatcactaag attaggcaca ttagcgaaac cattgtagcg attaaagcac aggctttctc
    21601 aagcgaagtg tttaccgaga gtgatcttaa caagatagtg ctagtaaatg gagtctatga
    21661 cctgagggat aacagcttta agactaagtt tgatccagaa ttgcatgcca ggtcaagcca
    21721 tcccgttgcc tatgcccccg aggcggcctg tgaaaccttt gagggttttc ttagggagac
    21781 cgtcggagct gaaaatatag atttcatctt tgagtggttt ggctataact tttatcgtga
    21841 atacactatt caaaaaatgc tattcatcta tggcagcggc ggtacgggta aatcaacact
    21901 gattaatatt ttacgtgaaa tgataggtgc tgataattat tcagccgtga cactgcagta
    21961 cctgatgcaa gaacgctttg caaaaatcgg cttatatcgt aagacagcca acttcgatac
    22021 cgatgctaaa cctcaatact tagcagatgg cgcaacgctt aaaatgttga ctggggaaga
    22081 tacgatacac gcagaccgga aaaacaaaga gcctattaat ttttacaatt acgccaagct
    22141 gtcttttgcc atgaatgagc tcccacctat gcgagatttc agtggaggac ttaagcgccg
    22201 catgatgatc cttgagatgg ataaggtatt aacgcaggag gttaaggcaa aatacccact
    22261 agataagatt atgagtgagg tgcctggtat ctttaacaga gcgatggagg ggcttagaaa
    22321 tgccttaagt aagagagatt tcagtattag tgccagcatg aggtcaagtg tcgagaaatg
    22381 ggaaaaaggc aacgatgtcg tggccatgtt ccttgaagac gagtgtgaac ttggtgaaga
    22441 cttcaaagtt cctgttaggg acgtctaccc agcctataaa ttctattgtc aggattcagg
    22501 ctacaaacct ttagctagga attcgtttac gcaaaggatg aatgaactga attttgaaaa
    22561 taagaacgca aaaatggggg gcaagaccgt aagatgttgg ataggtttta ggataaaagg
    22621 agaattttaa agggttacgt ttttcaataa aaaaggtaaa caggagacat aaggttacgt
    22681 agttacgcag aattcagact gataaaaaat tttataagtt gaaaaaaaac gtaactacat
    22741 aactttcctg aaaaaacttt cctgtttaag tcgatttaca taactaacgc aacttttatg
    22801 caacctcaaa aaacctttca tagcaatagt tt
//
LOCUS       DARYYD010000034        20892 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.034, whole genome shotgun sequence.
ACCESSION   DARYYD010000034 DARYYD010000000
VERSION     DARYYD010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20892
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.034"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            123..1538
                     /locus_tag="TV188_001290"
     CDS             123..1538
                     /locus_tag="TV188_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1534642.1"
                     /translation="MRKNKLLRMIMLMTLLVPHLETARVLAEDTGAEASQVPATANEA
                     AIAQTGESTSTAAATSATDNSSSTTETTPNSGEPGATGSSSNTASSGSASGSTGQSTP
                     TSPAASPQPAPEVATQASQPALNIVPAAPTVDLSLTLALPSVNTYAAYVTHWSGQSAY
                     THNLLSRRYGIKAEQLDSFLKSTKIKYDEKRINGAALLQWEKKSGLDVRAIVAIAMTE
                     SELGTKGNATLLGSNMFGYALFDLDSKKPNQFNDELAIVKLTQETIIKNSNLNFEQQD
                     QKADKFAKKQLNFASDGGLYFTDTNGIGKRRAEIMEKLDAWIDQHGGTPEIPAELKIQ
                     SSSSFAVVPTGYKLSKSYDILSYQASSYAWGQCTWYVYNRAKELGYQFDSFMGNGGDW
                     RFKSGYSISKEPKVGYAVSFAPGQAGADGLYGHVSIVEDVRKDGSILISESNCLGLGQ
                     ISYRTFTAEQANQLTYVVGKS"
     gene            1740..5491
                     /locus_tag="TV188_001291"
                     /pseudo
     CDS             1740..5491
                     /locus_tag="TV188_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922617.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NEAT domain-containing protein"
     gene            5720..6625
                     /locus_tag="TV188_001292"
     CDS             5720..6625
                     /locus_tag="TV188_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HEL1534643.1"
                     /translation="MKIINEEHMIKRLFKKLMGGLVVLLVCLAAIGGKAYADKGELYS
                     CVIRRDYRHPVSGQIEDSGGEHAFEIGQGMVEGTVYSNGMLEVTSAGDLYLTFRMSLA
                     DFSGNYQFWVQPGGTGAFQAAAYSVTKVGTDTNGTTKDIAIALPDVNTVVRGSMYVEP
                     MGREVVFYLSPSELQEGYSGDMVASFAAGEAKTDHAVTAPAKADEKKAPSKPDSKDAK
                     SAPNPSARPVGQSSSPKKQSNPSKKGQAVGLSTSLDKSKQESSQKPVNNPLPVLVYYV
                     PTALLLSGALVLFIKKKRKNNEESH"
     gene            6609..7493
                     /gene="isdE"
                     /locus_tag="TV188_001293"
     CDS             6609..7493
                     /gene="isdE"
                     /locus_tag="TV188_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HEL1534644.1"
                     /translation="MKKVIKLIGLAVLSLVLSACVDQHPRAEKKADKERIVATSVAVV
                     DICDRLSLDLVGVCDSKLYQLPKRYDAVKRIGLPMNPDMEVIASLKPTWILSPNSLQN
                     DLEPKYQQLDTEYGFLNLTSLEGMYQSIDDLGDLFDRKKEAKRLRADYEEFYRAFKKK
                     HKGQKKPRVLILMGLPGSYLIATNKSYVGNLLELAGGENVYHSEDKEFLSANPEDMLQ
                     QQPELILRTAHAIPDKVKDMFDKEFAENDIWKHFEAVKSQQVYDLDNTLFGMSAKFNY
                     KEALNHLSQIFYGAKEVK"
     gene            7495..8517
                     /locus_tag="TV188_001294"
     CDS             7495..8517
                     /locus_tag="TV188_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEL1534645.1"
                     /translation="MQQGSQYSDQVTAARKRTTRLVYMVLLLMLLFGLMLYAVSVGGL
                     SVSYQRIFNGLFVAYDSEVALIYDLRFPRIVIALLAGAGIATSGVLFQAILKNPISDP
                     AIIGVCSGASFMVLLSSLLLPQLLFYGPLLSFVGGCVSFLMIYTLSWKKGLQPIRIIL
                     TGIAINALFLGLSRAITDFSKTSNPFVNALLSGNISQKTWADVGVLWPYTVLGLLLAI
                     GLARQCDLLLLNDGLIRNLGIDSNYLRLGISLVAVLLAAVSTSIVGVVSFLGLIVPHI
                     GRLLVGSKHSYLIPFSALLGAFVFLLADTLGRQLCYPLEISPAVIMSIVGGPYFIYLL
                     RRSDVI"
     gene            8514..9296
                     /locus_tag="TV188_001295"
     CDS             8514..9296
                     /locus_tag="TV188_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534646.1"
                     /translation="MSHEQGLIRVEDLSFTYRDRPILDRLSFTIPKGKITTIMGANGC
                     GKSTLLGLLTKNIPVKSGQIFLEGQAISSISLKQFAQKVAVVHQDNQAVADLLVGDLV
                     AVASQAHRRFFKGSSQEDDDIVAWALEVTNLRELAFREMQELSGGEKQRVWIAMALAQ
                     KTGVLVLDEPTTYLDIKYQLDILALIKKINQELGMTIIMVLHDINQALAVSDCVLGLQ
                     KGAIYAQGSPQEVLDQAFVEAVFGVSLPFIEKQDRRFVLTTL"
     gene            9342..11105
                     /locus_tag="TV188_001296"
     CDS             9342..11105
                     /locus_tag="TV188_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HEL1534647.1"
                     /translation="MNDTTEKISRAKKKMLLRRLKERIAPKRFLLYVSAFLSWLQFLM
                     RLMSFYLIAKQFTAFLAGQALQLTRLLVILLILNAVGFGLAMIAKQLQGLASQFARDS
                     LKQSFFDAFIAMDGQFDQQSTEADVLTVASQGIDSLDTYYSYYLSLAMLTAFNCTTVL
                     LLVFLIYPIGGLVFILSLPLIPISIVAMQKRSKRIMNHYWSTYMDVGNLFMDDLKGLN
                     TLYSYQADERYEESFVNKAEAFRKATMQLLGFQLQAVGYMDAVMYLGIGLSGFLAVQA
                     LSAGGISFFDFLFFILIATEFFAPIREQGYGMHLVMMNTKMADQIFGFLDSVEAVDQD
                     KGVALPAFDRIDIQDLSFSHGEKALLRDITMTIKKGELTAVAGVSGQGKTSLAQLLLK
                     RYQADSGQIFLGDVTIDLASKQAINQEILYVSDQSTLLNMSIYENLAMAAQLTRKELL
                     SWIDEHGILSFIYWLPDGIDTIVGENGCHLSAGQRQQVICARALLSQRSCYIFDEATS
                     SLDAENEAAIHRLLQQLAKQAIVIVITHKMKYLKQADQVLFLSPEQSASLASPRELYR
                     HHLAYRQLVDTQVELEANLYG"
     gene            11098..12780
                     /locus_tag="TV188_001297"
     CDS             11098..12780
                     /locus_tag="TV188_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534648.1"
                     /translation="MVKSDYSTYRLVLRLLAMMKHLLAWIALAVMFAVLGFVLTVGIP
                     TSLAYLGLEVMAGHAITFKWLYLFVAMALLRGLVRYGEHYFGHFVAFHSLAAFRRIVF
                     KKLRALSPARLDSQDSGHLLKMIGEDIEALEVFFAHTLAPICTAFISASLMAYYLWQV
                     SWKLALGAIVTYVLLAVIIPVYFSNVLQSLLKKQNEGRRAYVSSFLESLRSVKDLLQF
                     QSIEKRFKLLSNQSKHVNALDRQVAQAQFLQMAITFLALGLSILTFAYVTLFELSQQT
                     VTFAGGLLAFVAFTASFAPFLELGRLPLGFKRAMNAARNVFQLLDEEALVDKGDQRIS
                     SVTRIAVEDLTFAYPKHQETIYHHLSVAFEKKGIIGIQGESGSGKSTLMKIIMKWYNW
                     QAGHIFLSEVDSQTLNAASLQANFAYVPQNAQLFQQTLRDNITLGRKDISDDDIMELA
                     EACGMKERILACDEGLDTLVRGSADFSAGEAQRLELMRALLKRADCYIFDEPTSNLDS
                     LNEAIFIDLIKKHCRGMVFLISHRPSTLACADQLFCVRNGFLKEVNNERVNH"
     gene            12761..13354
                     /locus_tag="TV188_001298"
     CDS             12761..13354
                     /locus_tag="TV188_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1534649.1"
                     /translation="MKGLTIKDIMTTGAFAALYFVCVGLGAMLSILFDRSGNMLYAPA
                     FAALLGGPVYMLLIAKLQTFGPISLVGIIMGSFFFLTGHFFASMLPAILFGCLADGIA
                     LLGKYQSRLVNLLSYLVFAFVNSGPIILMWLLKDAYIQSLLARGKDMAYVNRIMYDFT
                     VANVSWFVGVVLLCALVGGLFGQYLLKKHFAKSGMLL"
     gene            13351..14031
                     /locus_tag="TV188_001299"
     CDS             13351..14031
                     /locus_tag="TV188_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1534650.1"
                     /translation="MRLDVRTKLLLLILANACFFFRIDGWLGTMIIGVLLGILFWLGQ
                     GRLAIGMTLLYALLLALSVLPLHVLPAYLFRLLSFAAVAGQLLYPSVLAALIFVKTTT
                     AYELVHGLRKWHVPEVCLLTLAVMLRFLPKIRQEGKIIRQSLKIRGIFLDSWAIVRQP
                     RRYMEYLLVPLLMSLLRSSQDLTIASLTKGLAIKKGASECFVSHLSWKDWGVQIWIFV
                     TIAYMVLQ"
     gene            13968..15422
                     /locus_tag="TV188_001300"
     CDS             13968..15422
                     /locus_tag="TV188_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534651.1"
                     /translation="MEGLGGTDLDICDDSLHGSPVIKAKQLQFSYTNRRQTACELRDC
                     QIEAGQFIVLCGQSGSGKSTFLKLLNGLIPDYFSGQLQGSLKVLSHQAGQASVEVLSR
                     QVSSVFQNPASQFFYREVKHELVFPCENQGLEPALILERLDTLAADFDIKDLLEADML
                     KLSGGQKQRVAIAAAIMQGTAIMVFDEPTANLDHASVAAVKAYLKQLKAAGKTIIVAE
                     HRLHYLLDLADHFYYFSAGRLERVLSPKDLLALPDQEREELGLRRCELTAVTKALRAK
                     TVFEHYDPEHALQIKQLEVKAGSRVLYHLNQLSFGAGQITGITGANGLGKSQLALYLA
                     GIFEAKEAKISYLGVTLPAKDRLSITSLVLQDVGLQLFSETVEKELNLGHHRHQATDD
                     LVNRLGLSQLLDKHPASLSGGEQQRVMIAASLLSDKEIVILDEPSSGLDLLQMQALVS
                     LLKELKQQKKVVIVISHDEELLDQACDSIYQLSR"
     gene            15786..17801
                     /gene="recG"
                     /locus_tag="TV188_001301"
     CDS             15786..17801
                     /gene="recG"
                     /locus_tag="TV188_001301"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEL1534652.1"
                     /translation="MLLKSSIANLKGLGPKSAEKFQKLGIYQIKDLLLYYPFRYEDFK
                     SKSALELLDGEKAVLTGRVVTPPSVQYYGFKRNRLSFKLKQGELVISVSFFNQPYLLE
                     KIVLDQEVAIFGRWDQKKAALTGMKLLMTLEDDLQPVYHVAQGISQPTLIKAIRSAFD
                     SGALAQLEENLPEPLIQKYRLLPRQAAVYAMHFPKHMEDYKQALRRIKFEEFFYFQMN
                     LQVLKLANKAEGNGLAIPFHQQAVAKKIAALPFSLTRAQQRSLEEILADMTSGAHMNR
                     LLQGDVGSGKTVIASLAMYAAQTAGFQSALMVPTEILAEQHYDSLCQLFPDLSIALLT
                     SGMKAAEKRAALSAIADGSVDMIVGTHALIQDAVTYHKLGLVITDEQHRFGVNQRRLF
                     REKGNNPDVLMMTATPIPRTLAITAYGEMDVSIIDELPAGRKPIITRWVKHRQLDSVL
                     AWVKTELAKGTQAYVISPLIEESETLDLKNAVALEAELKDYFKASASVALMHGKMKAD
                     DKEMIMQRFKAKEIDVLVSTTVIEVGVNVPNATIMLIMNADRFGLSQLHQLRGRVGRG
                     SKQSYAILVADPKTDSGKERMTIMTTTNDGFVLAEADLKLRGSGEIFGTRQSGLPEFK
                     TADIVEDYHILEEARRVAAEIVAAKDWQLDPRWAPILANLRVADQFD"
     gene            complement(17921..18886)
                     /locus_tag="TV188_001302"
     CDS             complement(17921..18886)
                     /locus_tag="TV188_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEL1534653.1"
                     /translation="MKEILVLHTGGTISMQADEAGKVSPNQNNPMNQVGLSLEHIHLT
                     VVDFLNLPSPHITPHHMLKMYHYIQQRASQFDAVVITHGTDTLEETAYFLDTMVLPVE
                     LPIVITGAMRSANEIGSDGIYNYLTALRVASHEKAKGKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGVVMKDDLLFFKTAEPRVRFELRHISGTVPIIKAYAGMGDGSI
                     LSLLTPDRIQGLVIEALGAGNVPPLAVSELEKLIASGIPVVLVSRCFNGIAEPVYAYR
                     GGGASLKRAGVMFVKELNAPKARLKLLIALNAGLTGQELKDYIEG"
     gene            18958..20346
                     /locus_tag="TV188_001303"
     CDS             18958..20346
                     /locus_tag="TV188_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEL1534654.1"
                     /translation="MTIKAVFFDIDGTLLNDRKNVQKTTQRAIQQLKKQGIMVGLATG
                     RGPAFVQPFLENFGLDFAVTYNGQYILTRDKVLYQNQLPKSTIYKIIRYASDKKREIS
                     LGTASGLAGSRIIDMGTSPFGQMVSSIVPRSLVKTVEGSFKNLIRRFKPQSFSNLVTI
                     MREPIYQIVLVASVDDTQKIKERFPHIKVTRSSPYSLDLISSGQSKIKGIERLGEMFG
                     FELSEVMAFGDSDNDLEMLSGVGVGVAMGNAEAVVKSGAHFTTASNNNDGISKALAHY
                     GLIHFDVEKSFKSRDDNFNKVKDFHRLMDGDTIETPRGYSLKEAGYRADFKVEELVEF
                     LYAASQGDKHRFSQALIDLHAALDKAAKKVQAKEHPESPLVGQVDALTDLLYFTYGSF
                     VLMGVDPQPIFETVHEANMGKIFPDGKAHFDPITHKIQKPDDWQERYAPESAIKKELD
                     KQLQKSLQRLEK"
     gene            complement(20632..>20892)
                     /locus_tag="TV188_001304"
     CDS             complement(20632..>20892)
                     /locus_tag="TV188_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1534655.1"
                     /translation="AKEVLGDFEKQAREAGLTEVKQVIEFGNPKTLLAHDIPDKEEVD
                     LIMVGATGLNTFERLLIGSSSEYILRHAKVDLLVVREHDKTL"
BASE COUNT         5596 a         4151 c         5093 g         6052 t
ORIGIN      
        1 aagaaaaggc ccttaccttt atccgagtat taaggcatta atacaaaaaa tcttgcattt
       61 tattttgctt caatgttata atgtaggtta gaatagagca gaaagaagtg attgaatact
      121 aaatgagaaa aaataaatta ttaagaatga taatgctgat gactcttctg gtacctcatt
      181 tagagaccgc aagagtattg gcagaggata caggagctga agccagccag gttccagcta
      241 ctgctaatga ggctgcaatc gcccagactg gtgagtccac ttcgacagca gctgctacct
      301 cagctactga caactcctca tcaaccactg agactactcc caacagtgga gaacctggag
      361 caacggggtc atcaagcaat acagctagct ctggatcagc ttctggttct actggacagt
      421 cgacacctac tagtccagca gctagccctc agccagcccc tgaagttgct acacaggcat
      481 ctcagccggc actgaatatt gttcctgctg ctcctacagt tgatttgtcc ttgactctgg
      541 ccctgccttc tgtaaatacc tatgctgctt atgtgacgca ttggagtggt cagagtgctt
      601 atacccataa cctcttgtct aggcgctatg ggatcaaggc agagcagctt gatagctttt
      661 taaagtctac caagatcaag tatgatgaga agcgaattaa cggtgctgcc ttgctgcaat
      721 gggaaaaaaa gagtgggcta gatgtgcggg cgattgtagc cattgcaatg acagaaagtg
      781 agctaggaac caagggaaat gcaaccttac taggctctaa catgtttggc tatgcgcttt
      841 ttgaccttga ttcgaaaaag ccaaatcagt ttaatgatga gcttgctatt gttaagctga
      901 cacaggagac gattatcaaa aatagcaacc ttaattttga gcagcaggat caaaaggctg
      961 ataaatttgc caaaaagcag ttgaactttg ctagtgatgg tggtctttac ttcacagata
     1021 ccaatggcat tggcaagcgt cgcgctgaga tcatggaaaa attagatgct tggattgatc
     1081 agcatggagg cacgccagag attccggctg agctgaaaat tcaatcctct tcaagctttg
     1141 ctgttgttcc tacaggctac aagctgtcta agagctatga tattttaagc tatcaggcgt
     1201 caagctatgc ttggggacaa tgtacctggt atgtttataa tcgcgctaag gagctaggct
     1261 atcagtttga ttcctttatg ggaaatggtg gtgactggag atttaagtct ggctacagta
     1321 tttctaagga gccaaaggta ggctatgcgg tttcctttgc tccaggtcaa gcgggtgctg
     1381 acggtcttta tgggcacgtc tctattgttg aggatgtcag aaaggacggc tccatcctga
     1441 tttcagagtc aaattgtctt ggcttaggtc agatttcata ccgcaccttt actgctgagc
     1501 aggccaacca attgacttat gttgttggaa aatcataagt aatcttcttg ctttaaaggc
     1561 gagaagtaca gaatttttgt aagaaaaaat ccagctctgt tgcagggctg tttttttctt
     1621 tgctttattg tgaaaaaaat ctcaaattca atcttgacaa aggcttgaca acataataaa
     1681 ttaagtgaga ttaataaaat aattaaatgg ctaataacat ttttagaagg ttcgaaataa
     1741 tgaaaagtat caataagtgc gccattcttg ctttatcaac gctggctctt gcccagtctg
     1801 cccagacggt tcgctcagag gctactcaag tctcttcaag tcttgtgacg actgtcaagc
     1861 ttaaggataa tattttattg ttcgaggaga tcggtcccta tgcggacaag tcagagggga
     1921 agctctatta taaaaatatc gagaaaattc tcattgatgg taaagagtat gacaaaaagc
     1981 tggagggtga ctatagctat gacatcaatt accaaggaat caaggtaaac gctaagaaca
     2041 tcacagaagg acagcatcag ctgcgcatcg tcaataagac taacggaggc attcttgtgg
     2101 tctttgacaa gaaaggaaat gatgttacct ttgtttctgc caagccttca gatgatacta
     2161 ctgcttcacc gcagcaagct gctgctaaga cagaaaagcc tgctaaggta actagccatg
     2221 atggcttagc gaccctatca tttatcacca aactagagac aacagaagga gagcttcttt
     2281 ttccggaaat tgatcgctat tccagcacca agcaaattaa ggaattagct catcaaatca
     2341 caaagatcaa ggtcaatgac caggactata aggatttggt ctatgattca gtaaaggaca
     2401 agcctggcta tgtgtctgac ctgaaggggc ttcatcttgg gacgacagct ttcaaggagg
     2461 gagaaaacaa ggttgtcatt tcctcacaaa gctttgaaga tgtcatcatt acagtgaaaa
     2521 agtcagggga gcaatacacc tttgtttctg ctaagcaaaa gcagagacaa ggatcccagc
     2581 aggaagcacc gcagggactt gattttacta agctggaaag cgcgatcaag gaagctgagc
     2641 gtatcattgc tagcgaggcc aataaagaac aggtcaagga cttgtctagc aagcttcagg
     2701 tgatcaagga gtcctatcgt cagattgaca atgaaaaatt gctcaaggag acctatgagc
     2761 ttttgatgga tagtatcaag tcctatcagg gaactgatct ggctgttacg gatctaaagg
     2821 caggaaccta taccttaacc tttaaggcca ataaggaaaa tacagaggaa gcctcaatgc
     2881 tgcagggagc atttgataag aaggccaagc tggtcgtcaa agaagatggc aagatggaga
     2941 tttcattgct caatacagct ctagggcaat ttttgattga cttttccatt gagagtaaag
     3001 ggcagtatcc aacctctgtc cgcactcagg ttggtgaacg cgatattaac aataactaca
     3061 ttagagtgaa tttaccctac cgattgagga gctggacaag cttcacaagg gtgctgtgct
     3121 agtatcagct atgggtggtc aggaaagcga cctacatcac tatgacaaat acaccaagtt
     3181 ggacatgacc tttagcgcta cagcaagtaa gggctggaca ggctatcagg ctgagattga
     3241 cgacaaggaa aaaggggtcg gctctgagcg tcttgaaaag gttttggtta agcttggtaa
     3301 ggaccttaac ggtgatggca aaatgtcacc tgaggaaatt gcgaagattg aaggtgagct
     3361 gcgcctagac cactatgatt tgacagatat ttcactctta aagcatgcta agcatattac
     3421 tgagctgcac ttagagggca atcagattgc aagcattcca aaggaaacct tcagtcaaat
     3481 gaccaatcta aggttcttaa atcttcgcag caatgtgatt acaaccctag ataaggatac
     3541 ctttgctcat aacagccagc taaaagagct ctatctctca agcaactata tgccaaatct
     3601 ggaggaagga ctatttagaa atcttggtca gctggatcag ctagatctgt caaaaaatag
     3661 aatcagcgtg attcgagatg gtgtctttaa tggtctatct cgcttgacct ccttggcctt
     3721 ggctgaaaat atcattactg aattttcaga aaatgctcta gcttcacttg ataatctaaa
     3781 cttctttgat gtttctgaaa accagttggg cagcctgcca agctccttga gtaagctaac
     3841 taagctttct tatatcgttg ccaatcgaaa ccaggtttta gatattgcta atattgactt
     3901 tagtcatatg ccaaacttat taaccgttga cttggcatca aatgagctaa ctaaaatccc
     3961 acagggagcc ttcaaggcta ataagcagct atcaaagctt aatgtctata ataacctttt
     4021 aacgaatatt agcgaagctg attttgcaga tctaaaggca ttggatcttg atcttaagtt
     4081 taactgccta agtggcgtta gtgataagct tagacagatc atgggaacaa ataagctaaa
     4141 cccacaaaag caatttgcta atctatctgc gactttaaat catcaagcga tgacctatca
     4201 ccaagggttt agcctgcttg atttgtatta ttgggagcag cagacactct caagcaccga
     4261 agcagaaatt agctctgttg aggattacaa taaacgcctt aaggcaagct cgtcagacat
     4321 cattgcctta ttaaatgagc gttatgctga ctgggatatt gtggtgcaat tgcagaaaaa
     4381 aacatcaacc ggtcaatatg tcaccgttga tgagagacgc ttgaataacg atccacaaga
     4441 tgagcttcaa ggctcctttg acctaaaggg agcaggtgtt tatcgtgttc gtaaggctct
     4501 tatcaccaag gaatttgcta agaagcgtga gcatatttat ctgacctcta atgatgttga
     4561 ggtcaaggag gatcagcttg caggtagtga ccagtctaag ggcttggata ttaataagct
     4621 tgaagatggt gtctactaca tcaaggcaag catgcttaaa aatgatttgc agtcagaatc
     4681 aatgtctcat caggctattg accaccgcgt caaattgatt gtgaataagg gtgtctatag
     4741 cctagaggtg acctttaagg gcatgaagat cggtaacctg acagggtatc tcggagagtt
     4801 gagctacttt gttgatggct accaaaggga tttgactggc agaccggttg gtaagacaga
     4861 aaaagcagag gttgtgtcct actttacaga tgtcacaggc aagcccctgt cagacgctta
     4921 tggcagcaat tacccacagg tgttgagatt taggctgatt gatcaggcta aaaaggatgg
     4981 cttggtacct cttcgcgtct ttgtgccaat tatggacgct atctctaagg gaacaggctt
     5041 ccagacagtc tttatgaagt tggatcttca aagcctgaca aaggataagg cacaattgcc
     5101 acactcagag gacaatcagg gacatggtac cataggtgag ctcttgcagc ctcacacagg
     5161 tatcattggt ggtcatacaa gtcctgctat tcctaatttg accaatcttt tgactaagaa
     5221 gtcagctgct ccaagcagta atgccaagga ggacgctaag accggtacag ataagcttaa
     5281 gagcctgatt tcttcacata aggcgtctaa ggctggtaca ggcaaggcct ctaagcaggc
     5341 tgctaagact agagccaaag ctaaatctaa ggctgctaaa catagtcagg agcagatgaa
     5401 agctgatcat cgcggccata tcattatcgg tctagcaagc tttattgtca tagcagttgg
     5461 tctcattctt ggtaggaaaa aattatttta agtcagtaga gagtctgttt gatgcactaa
     5521 gagcttggtt taatcgcttg tagtcatcaa ggcttatcaa cgatacgtaa aggcatgcct
     5581 gtttctaatg atttcttaag cttacccttg gtaagtgagg aatgggtatg cttttcgtat
     5641 ttgaggtgtt ataatagtca aataagagta ggtcttggcc tgcgtctaaa tctatgcctt
     5701 atttgattgt cgtaaggaaa tgaagatcat taatgaggaa catatgataa agagattatt
     5761 caaaaaatta atgggtggct tggtggtatt gctggtttgc ctagcagcta taggaggtaa
     5821 ggcctatgct gataagggtg agctttattc ctgtgtgatt aggcgagatt atcgtcaccc
     5881 ggtttcaggg caaattgaag atagcggtgg tgagcacgct tttgagattg gccaaggtat
     5941 ggtggaagga acagtttata gcaatggtat gctagaggta acctcggctg gggatttgta
     6001 tctgaccttt cgcatgagtc tagctgattt ttcaggtaac taccaatttt gggttcagcc
     6061 gggtggtaca ggggcttttc aggcggcagc ctacagtgtc accaaggttg gcactgatac
     6121 caatggcaca acaaaggata ttgcgattgc tttgcctgat gtcaatacgg ttgttagagg
     6181 cagcatgtac gtagagccta tgggcagaga ggttgtcttt tacctgtcac catctgagct
     6241 acaagaaggc tacagtggag atatggtagc tagctttgca gcaggagaag ccaagacgga
     6301 tcatgcggtg acagctcctg caaaggcaga tgagaagaaa gctcctagta aaccggactc
     6361 aaaagacgcc aagtcagctc ctaatccctc agcaaggcca gttggtcaat caagcagtcc
     6421 caaaaaacag tcaaatccct ctaagaaggg tcaggcagtt ggtttgagca cttcgctaga
     6481 taaaagtaag caagagtcgt cccaaaagcc agtaaataat ccattgccag ttctggttta
     6541 ctatgtacca acagctcttt tgttgtcagg agccttggtc ttgtttataa agaaaaagag
     6601 aaaaaacaat gaagaaagtc attaagctta ttggattagc tgttttgtcc ttggtgctat
     6661 ctgcttgtgt ggatcagcac cctagggcag agaaaaaggc tgataaggag agaattgttg
     6721 ccacctctgt ggctgttgtt gatatttgtg atcggctaag cctagatttg gttggggtct
     6781 gtgacagtaa gctataccaa ttgccaaagc gttacgatgc tgtcaaaagg atcggtctgc
     6841 cgatgaatcc tgatatggag gttattgctt ctctaaagcc aacgtggata ctcagtccca
     6901 attctctgca aaatgattta gagcctaaat accagcaatt ggatacggaa tatggctttt
     6961 tgaatttaac tagccttgaa ggcatgtacc agtcgattga tgatttgggg gacttgtttg
     7021 atcgcaaaaa ggaagctaag cgcttgcggg ctgattatga ggagttttac cgggccttta
     7081 agaaaaagca taaagggcaa aaaaagccta gggttcttat tttgatgggg cttcctggca
     7141 gctatctgat tgctacaaat aaatcctatg ttggtaatct gcttgagctg gctggtggtg
     7201 agaatgttta tcactctgag gacaaggaat ttttgtctgc caatccagaa gacatgcttc
     7261 agcagcagcc tgagctgatt ttgcgtactg cccacgccat tccagacaag gttaaggaca
     7321 tgtttgataa ggaatttgct gaaaatgata tttggaagca ttttgaagct gtcaagtctc
     7381 agcaggttta tgatttagac aatacccttt ttggcatgag tgctaagttt aactacaaag
     7441 aggctttgaa ccatctgtca caaatctttt atggagcaaa ggaagtcaag taagatgcag
     7501 caaggtagtc aatattctga tcaagtcaca gcagcaagaa aaaggaccac tagactggtc
     7561 tatatggttc tattgctcat gctgctgttt ggtttaatgc tatatgcggt ctctgttggg
     7621 ggcttatctg tttcttatca gaggatcttt aatggcttat ttgtagcata tgattcagag
     7681 gtagccctta tttacgattt acgctttcca aggattgtga ttgctttatt ggctggggcg
     7741 gggatagcaa catctggggt cttgtttcag gcgattttaa aaaatcctat ttcagatccg
     7801 gcgattattg gggtttgcag tggggctagc tttatggtct tgttatctag cctgcttttg
     7861 ccgcagctct tgttttatgg tcctttgtta tcatttgtgg gaggctgtgt ttcttttttg
     7921 atgatttata ccttgtcctg gaagaagggc ttgcagccga tacgcatcat tttgacagga
     7981 atagctatca acgccttgtt tttaggcttg tctcgtgcga ttactgattt ttcaaaaacc
     8041 agcaatccct ttgtcaatgc gctgttgtca ggaaatatta gtcaaaaaac ctgggcagat
     8101 gttggtgtgc tgtggcctta tacagtgctt ggcctgctgc ttgcgatagg cctagcaagg
     8161 cagtgtgatc tactgctgct aaacgatggc ttgattcgta atttaggcat tgatagtaat
     8221 tacctgcgct taggaatctc gttggttgcg gtcttactag ctgctgtttc cacctcgatt
     8281 gtgggtgtgg tgtcattttt aggcctgatt gtgccgcata ttggccgcct tttagttggc
     8341 agtaagcata gctatctcat tcctttttct gccctgcttg gcgcctttgt ctttttgctg
     8401 gcagatacct taggaaggca gttgtgttat cccttggaga ttagcccagc tgttatcatg
     8461 agcattgtcg ggggacctta ttttatttat ctgttaagga ggtctgacgt gatatgagtc
     8521 atgagcaagg cttgattcgt gtagaggatt tgtcctttac ttatcgtgat aggcctattt
     8581 tagataggct gagctttacc attccaaaag gcaagataac gacaatcatg ggggcaaacg
     8641 gctgtggcaa atcaacccta ctaggtctgc tgactaaaaa tatccccgtt aagtctgggc
     8701 aaattttctt agagggacaa gctattagct ctattagtct taagcagttt gcccaaaaag
     8761 tagccgttgt gcatcaggat aatcaggcgg tagcagatct tctggtgggt gatttggtgg
     8821 ctgtggcaag ccaagcccat cggcgttttt ttaagggatc aagtcaagag gacgatgaca
     8881 ttgttgcttg ggccttagag gtgactaatc taagggaatt ggcctttagg gaaatgcagg
     8941 agctatctgg tggtgaaaag caaagggtct ggattgctat ggcgcttgcc caaaaaacag
     9001 gtgtcttagt gcttgatgag ccaaccactt atcttgatat taagtaccag ctggacattt
     9061 tagccctcat caaaaaaatc aatcaggagc taggaatgac cattatcatg gtgttacatg
     9121 atattaatca ggccttggct gtttcggatt gtgtgcttgg gctgcaaaaa ggtgccatct
     9181 atgcccaagg cagtccacag gaggttcttg atcaggcttt tgtggaggcg gtttttgggg
     9241 tgagcttgcc ctttattgaa aagcaggata ggcgatttgt tcttaccact ttatgagaca
     9301 aataaaaaat gaatgataga taggaataag gcgacgatta tatgaacgat acaactgaaa
     9361 aaatatcacg cgcaaagaaa aaaatgcttt taaggcgttt aaaggagcgt attgctccta
     9421 agcgtttttt gctttatgtg tcggcctttt tatcttggct gcaatttttg atgcgtttaa
     9481 tgagctttta cttaattgct aagcaattca cagccttttt agcaggtcaa gccctgcaat
     9541 tgacaaggct gcttgttatc cttttgattt taaatgctgt tggctttggc ttggcgatga
     9601 ttgcaaagca gctgcagggc ctagcttcgc aatttgcgcg tgactcgctc aagcaatcct
     9661 tttttgatgc ctttattgct atggacgggc aatttgatca gcagtcaaca gaggctgatg
     9721 tgttaacggt tgcctcacaa gggattgata gcttggatac ctattattcc tattacctat
     9781 cgcttgcaat gctaacagct tttaattgca caacggtctt actgcttgtt tttttgatct
     9841 atcctatagg gggcttggtc tttatcttgt ctttgccctt gattcccata tccattgttg
     9901 ctatgcaaaa acgctctaaa aggatcatga accattactg gtcaacctat atggacgttg
     9961 gcaatctatt tatggacgat ctcaaggggc taaataccct ttattcctat caggcagatg
    10021 aaaggtatga ggaaagcttt gtcaataagg cagaggcctt tcgtaaggct accatgcagc
    10081 tcttgggctt tcagctgcaa gcggttggct atatggacgc tgtcatgtat cttggcattg
    10141 gcttatctgg ctttttagcg gttcaggctc tgtcagctgg tggtatatcc ttttttgact
    10201 ttctcttttt tatcctgatt gcaacggaat tttttgcccc tattagggag cagggctatg
    10261 gcatgcacct agtcatgatg aatactaaaa tggcagatca aatctttggc tttttagata
    10321 gcgttgaggc tgttgaccaa gacaagggag ttgccttacc ggcctttgat cgtattgata
    10381 ttcaagattt gtccttttca catggggaaa aggctttgct aagagacatc acgatgacta
    10441 tcaaaaaggg tgagctaaca gctgttgcag gtgtttcagg acagggtaag actagtcttg
    10501 cacagctcct gttgaagcgc tatcaggcag atagcggtca gatattcctt ggtgatgtga
    10561 cgattgatct ggcttctaaa caggccatca atcaggaaat actctacgtt tctgaccagt
    10621 caacgctgct taatatgagt atttatgaga accttgctat ggcagctcag ctgactagaa
    10681 aggagctgct tagctggatt gatgagcatg gcattttgag ctttatttac tggctacctg
    10741 atgggattga taccattgta ggtgagaatg gctgtcactt atctgcaggg caaagacagc
    10801 aggtgatttg tgctagggcc ttattgagcc agcgttcctg ttatattttt gatgaggcta
    10861 cctcaagtct tgatgctgag aatgaagctg ctattcacag actgcttcag caattggcta
    10921 aacaggccat tgtaattgtc atcactcata agatgaaata tttgaagcag gctgatcagg
    10981 tgctcttttt aagccctgag cagtctgcta gcttggctag cccaagagag ctttaccgcc
    11041 atcatttggc ctatcgtcaa ttagttgata cacaagtaga attggaggca aatctttatg
    11101 gttaagagtg attacagcac ctaccggcta gttttacgat tgcttgctat gatgaagcat
    11161 ttgctggctt ggatagctct ggcggtgatg tttgcagtgc tgggctttgt gcttaccgtt
    11221 ggcattccta ccagcttagc ctatctgggc ttagaggtga tggctggtca tgctattacc
    11281 tttaaatggc tttatctatt tgttgctatg gcactgctaa gggggcttgt tcgttatgga
    11341 gagcattatt ttgggcattt tgttgccttt catagcctgg cagcctttcg caggattgtc
    11401 tttaaaaagc taagagcact ctcgccggca cgcttagaca gtcaggacag cgggcacctg
    11461 ttaaagatga ttggcgagga tattgaggcc ttggaggtct tttttgccca cacgcttgcc
    11521 cctatttgta cggcgtttat ttcagctagc ttgatggcct attacctttg gcaggttagc
    11581 tggaagttag ccttgggggc tattgtgacc tatgtgcttt tggctgttat tattccagtg
    11641 tatttttcaa acgtccttca atcactgctc aaaaagcaaa atgaagggcg cagggcttat
    11701 gtgtcaagct ttttagagag tctcagatct gttaaggatt tgctgcaatt tcaaagcatt
    11761 gagaagcgct ttaagctctt atccaatcag agcaagcatg ttaatgcgct tgatcgtcag
    11821 gtggcacagg ctcaattttt acaaatggcg ataacctttt tggctcttgg cttgtctatt
    11881 ttgacctttg cttatgttac tctttttgag ctgagtcagc agacggtgac gtttgctggt
    11941 gggttgctgg cttttgttgc ctttacagcc tcctttgcac cctttttaga attggggcgt
    12001 ttgccgcttg gcttcaagcg tgccatgaat gctgctagga atgtctttca gcttttagat
    12061 gaagaagcgt tagtagataa gggagatcag cgtatttcct cggtaacaag gattgctgtt
    12121 gaggatctga cctttgctta tcccaagcat caggagacta tttaccacca cttatccgtc
    12181 gcttttgaaa agaaaggcat tatcggtatt cagggagagt caggctctgg gaagtcaact
    12241 ctgatgaaga tcattatgaa atggtacaat tggcaagctg gtcatatttt cctgagtgag
    12301 gttgacagtc aaacgctaaa tgctgcttcc ctacaggcta actttgccta tgtcccacag
    12361 aatgcgcagc tatttcagca aacacttcgt gacaatatca cacttggtcg taaggacatt
    12421 tcagatgatg atatcatgga acttgctgag gcctgtggca tgaaggagcg tatcctagcc
    12481 tgtgatgagg ggctagatac cctagtgaga ggatcagcag acttttcagc tggtgaagcc
    12541 cagcgcttgg aattgatgcg ggctctattg aagcgggcgg attgctatat ttttgatgag
    12601 ccaacatcaa acttagattc gctgaatgaa gccatcttta ttgatttgat taaaaagcat
    12661 tgccggggaa tggtcttttt gatttcacat cggccatcca ccttggcctg tgcagaccag
    12721 ctattttgtg tgagaaatgg ttttttgaag gaggtaaaca atgaaagggt taaccattaa
    12781 agatatcatg acaacaggcg cctttgccgc cctctatttc gtttgtgtgg ggctaggagc
    12841 catgctgagc attctgtttg atcgctcagg caatatgctc tatgcgccag cctttgcggc
    12901 cttgcttggc gggccagttt atatgctatt aatcgctaag ctgcagacct ttggaccgat
    12961 aagcctagta ggaattatta tgggaagctt tttctttttg acaggtcatt tttttgcttc
    13021 aatgctacca gctattcttt ttggctgttt ggcagatggc atagcccttt taggaaaata
    13081 tcaatctaga ctagtgaatc tcttgtctta tcttgttttt gcctttgtta acagtggtcc
    13141 tattatttta atgtggctgt tgaaggacgc ctatatccag agtcttttag cgcgtggtaa
    13201 ggacatggca tatgttaacc gtatcatgta tgactttacc gttgcaaatg tcagctggtt
    13261 tgttggtgtt gtccttcttt gtgccttagt aggtggcctt tttggtcaat acctgctgaa
    13321 aaagcatttt gctaagtcag gaatgctttt atgaggcttg atgttcgcac aaaattgctc
    13381 ctgttaattc tagccaatgc ctgcttcttt tttcggattg atggctggct ggggacgatg
    13441 attataggtg ttttgcttgg cattttgttt tggcttggtc aagggcgtct ggcaatcggt
    13501 atgacactgc tctatgcctt actgcttgct ttgtctgtat tgccgcttca tgtgctgcca
    13561 gcctatctgt ttaggctgct gagctttgca gctgttgctg gtcaattgct ttacccatct
    13621 gtgcttgctg ctttgatttt tgtcaagaca acgactgcct acgagcttgt gcatgggctg
    13681 cgaaaatggc atgtgccaga ggtttgtctg ttgactcttg ctgtcatgct gcgtttttta
    13741 cctaagatca ggcaagaagg aaagattatt cggcaatctc tgaaaatcag gggcattttc
    13801 ttggacagct gggctattgt cagacagcca aggcggtata tggagtatct cttggtaccg
    13861 ctgttgatgt cattgctgag aagtagtcag gacttaacca ttgctagcct aacaaaaggg
    13921 ctagcaatca aaaagggagc aagtgagtgc ttcgtatcac atctatcatg gaaggattgg
    13981 ggggtacaga tttggatatt tgtgacgata gcctacatgg ttctccagtg atcaaggcaa
    14041 agcagctgca gttttcctat accaatcgta ggcagactgc ctgtgagctc agggattgtc
    14101 agatagaggc aggtcaattt atcgtgcttt gtggtcagtc aggctcaggc aagtcaacct
    14161 ttcttaagct gctcaatggc ttgattccag actatttttc aggacaatta caaggaagtc
    14221 tgaaagtact gtctcatcag gctggtcagg ctagtgttga agtgctgtca aggcaggttt
    14281 cctctgtctt tcaaaaccca gccagccaat ttttctatcg tgaggtcaag catgagcttg
    14341 tttttccttg tgaaaatcaa ggcttagagc cagctcttat ccttgagagg ctggatacct
    14401 tggcagctga ttttgacatc aaggacttac tagaagcaga tatgcttaag ctatctggtg
    14461 gtcaaaagca gcgggtggct attgcagcag ctatcatgca agggacagct atcatggttt
    14521 ttgatgagcc aacagccaat ttggaccatg ctagtgtagc agcggtcaag gcttatttaa
    14581 agcagcttaa ggctgctggc aaaaccatta ttgtcgctga gcaccgcttg cattatttgc
    14641 tggatttggc agaccatttt tactattttt cagctggtag gctagagcgc gtattaagcc
    14701 ccaaggatct gctagctttg ccagatcagg aacgtgagga gctaggacta agacgatgtg
    14761 agttgactgc tgtgactaag gctttgcggg caaaaactgt ttttgagcat tatgatccag
    14821 agcatgcctt gcaaatcaag cagctagagg tcaaggcagg cagcagggtt ttgtatcacc
    14881 tcaatcagct cagctttggt gcagggcaaa tcactggcat taccggagct aacggtttgg
    14941 gaaaatcgca gttggcttta tatctggcag gtatttttga agcaaaagag gccaagatca
    15001 gctatctggg tgtcaccctg cctgctaagg acaggctttc aatcacaagc ctagtgttgc
    15061 aggacgttgg gctacagcta ttttcggaga cggtagaaaa ggagcttaat ctaggtcatc
    15121 atagacatca ggctactgat gatttggtga ataggcttgg gctttctcag cttctagaca
    15181 agcaccctgc cagcctatca ggtggtgagc agcaaagggt gatgattgct gccagcctct
    15241 tgtctgacaa ggagattgtc attcttgatg agccaagcag tggcttagat ctgctgcaaa
    15301 tgcaggctct ggttagtctt ttaaaggagc taaagcagca aaaaaaggta gtgattgtca
    15361 tctctcatga cgaggaatta ctggatcaag cctgtgatag tatctatcag ttgagcaggt
    15421 aaaggcctag ccttgctcaa gcggtctggt gctgtattgg tgatggcttt atcgctcctt
    15481 ggagcagcag gtgttcctgc ttgatctgat aaccactagc tgcgattgac caatcacaag
    15541 ccgccaactc ttgacaagct agcagtagct atcacaattc tagggcatat cttggcctag
    15601 caagcagtgc tgtattgttt atatgccact cttcatcttt tagttaggcc gtcctagcgg
    15661 ccgcactaag ggtgtgttag gatcggctaa tacctcaagg catctacagt aagaaaacga
    15721 gcctcttcct ttttggagag gctcttgatt tttgatataa taatgaaaaa gaaagcgagg
    15781 ttgagatgct gttaaagagt tcgattgcta atttgaaggg tcttggtcca aagtcagctg
    15841 agaaatttca aaaattaggc atttatcaga tcaaggactt gctactctat tatccttttc
    15901 gctatgagga ttttaaaagc aagtcagcct tagagctttt agatggtgaa aaggctgtcc
    15961 ttacaggtag agttgtgact ccaccaagcg ttcaatacta tgggttcaag cgtaatcgcc
    16021 tgagctttaa attgaagcag ggggagcttg tgattagtgt cagctttttc aatcagcctt
    16081 atctgcttga gaaaatcgtc ttggatcagg aagtggctat ctttggtagg tgggatcaaa
    16141 aaaaagcagc cttgacaggt atgaaattgc tcatgacctt agaagatgat ttgcagccag
    16201 tttatcatgt ggcgcagggg atcagtcaac ccaccctgat taaggcgatc agatcagcct
    16261 ttgatagcgg tgccttagct cagctggaag aaaatttacc agagcccttg attcagaaat
    16321 accgcctgct gccgagacaa gctgctgttt atgccatgca ttttcctaaa catatggagg
    16381 attataagca ggccctgcgc cgtataaaat ttgaagaatt tttctatttt cagatgaatc
    16441 tgcaggtttt aaagcttgct aacaaggcag agggcaatgg gttagcgatt ccttttcatc
    16501 agcaggcagt ggcaaaaaag attgctgctt tgcccttttc actgaccaga gctcaacaaa
    16561 gaagcctgga ggaaatctta gcagatatga cctcaggggc tcatatgaac cgtctgttgc
    16621 agggggatgt cggctctggc aagacagtga tcgcaagcct tgccatgtat gctgcccaaa
    16681 cagcgggatt tcaatcggca ctcatggtgc caactgagat tttagctgag cagcattacg
    16741 atagtctttg tcagctcttt ccagatttgt ctattgccct gttgacatcg ggtatgaaag
    16801 cagctgaaaa aagagcagct ttatcggcta ttgctgatgg gtctgtggat atgattgttg
    16861 ggacgcatgc cttgatccaa gacgcagtga cctatcataa gctagggctg gtgattactg
    16921 atgaacagca ccgttttggg gttaatcagc gtcgcttgtt tcgcgaaaaa ggcaacaatc
    16981 cagatgtttt gatgatgaca gctactccca tacctagaac cctagccata actgcctatg
    17041 gtgagatgga cgtttccatt attgatgaat taccggcagg gcgaaagcca atcatcactc
    17101 gctgggtcaa gcatcggcaa ttagatagtg tgctggcctg ggtaaagacc gagcttgcta
    17161 aggggacaca ggcctatgtt atctctcctt tgatcgaaga atctgaaact ctagatttga
    17221 aaaatgcggt agctttagag gctgagctga aggattattt taaagcttca gctagtgttg
    17281 ccttgatgca tggcaaaatg aaggcagacg acaaggagat gatcatgcag cgctttaagg
    17341 ctaaggagat tgatgtcttg gtgtcaacaa ccgttattga ggttggtgtc aatgtgccaa
    17401 atgccaccat catgctgatc atgaatgctg accgctttgg ccttagccaa ttgcatcagt
    17461 tgcgtggtcg tgttgggcga ggcagcaagc aatcctatgc tattttggtg gcagatccta
    17521 agacagactc aggcaaggag cgtatgacca tcatgacaac gactaatgat ggctttgtgc
    17581 tggcagaggc tgacctcaag ctgcgtggct caggagagat ttttgggacc cgtcaatcag
    17641 gtttgccaga gttcaaaaca gctgatattg tagaggatta tcatatccta gaggaggcaa
    17701 gacgagtcgc tgctgagatt gttgcagcta aggattggca gctggaccct agatgggctc
    17761 cgattttggc taatcttcgt gtcgctgatc agtttgatta gatgtgaggc tgacttgctg
    17821 gacagagcta atataaaaac acgacaagag gttcttagct gaccgagtcg tgctttttgt
    17881 gctatagatg aggagtagta gcctgtgatt ataggagagc ttagccttcg atataatcct
    17941 tcagctcttg acctgtaagc ccagcgttga gggcgatgag caattttaac ctggccttag
    18001 gggcatttag ctccttgaca aacataacac cagccctttt taagctggca ccacctccgc
    18061 gataagcata aactggctct gctatgccat tgaagcagcg cgagaccaag acaacaggaa
    18121 tcccagaggc gattaatttt tcgagctcag atactgctag gggaggaaca tttccagcgc
    18181 cgagggcctc aatcactagt ccctgaatcc tatcaggtgt caaaaggctt aaaatacttc
    18241 catctcccat accagcatag gccttgataa tcggaactgt gccagaaata tgacgaagct
    18301 caaagcgaac ccttggctca gcagtcttaa agaacagtaa atcgtccttc atgacgactc
    18361 ccaaagggcc atgagtcggt gtttgaaagg tcgaaacatt ggtggtatgc gttttggtga
    18421 catacttagc ggcatgaatt tcatcattca tcacaaccag cacccccttg cccttggctt
    18481 tctcatggct ggctacccta agcgctgtta ggtagttata gataccatcg cttccaatct
    18541 cgttggccga gcgcatagca cctgtgataa caataggcaa ctctacaggc agcaccattg
    18601 tgtctagaaa ataagcagtc tcttctaagg tatctgtacc atgtgtgatg accactgcat
    18661 caaactgact agccctttgt tgaatgtaat gatacatctt gagcatgtgg tgaggggtga
    18721 tgtgcgggct tggcagattt aaaaaatcca caacagttag gtggatatgc tccaggctaa
    18781 ggccaacctg attcattgga ttgttttgat ttgggctcac cttgcctgct tcatcagcct
    18841 gcattgaaat ggtgccgccg gtatgtaaga cgaggatttc cttcatttga tactcatact
    18901 tctttcaatt tatgatataa tttattttat cacaaataga agagagaaca gaaggatttg
    18961 acaataaaag cagtcttttt cgacattgat ggaaccctgc ttaatgatcg aaaaaatgtt
    19021 caaaaaacga cgcaaagggc tattcagcaa ttaaaaaaac aaggtattat ggttgggctg
    19081 gcaactggtc gtggacctgc ttttgtgcag ccctttttag aaaattttgg cttggatttt
    19141 gcagtgacct acaatggtca atacattttg acacgagaca aggtcttgta tcagaaccag
    19201 ctgccaaagt caaccattta taaaatcatt cgctatgcta gcgataaaaa gcgcgagatc
    19261 tccttaggaa cagcttcagg tcttgctggg tctcggatca ttgatatggg aaccagtcca
    19321 tttggtcaga tggttagcag tattgtgcca aggagtctgg tcaagacggt tgagggcagc
    19381 tttaaaaacc tcatcagacg ctttaagccg caaagcttca gcaatcttgt taccattatg
    19441 agagagccga tttatcagat tgtcttggtt gcttctgttg atgacaccca aaaaatcaag
    19501 gaaagattcc cgcatatcaa ggtaaccaga agcagccctt attccttaga tttgatttct
    19561 agcgggcagt ctaaaatcaa gggcattgaa cgcttgggcg agatgtttgg ctttgagctc
    19621 tcagaggtca tggcctttgg cgactctgat aatgacttag aaatgctctc aggcgttggt
    19681 gttggtgttg cgatgggaaa tgctgaggca gtggttaaaa gcggtgctca ctttacaaca
    19741 gcttcaaata acaatgatgg tatctctaag gcgctggcgc attatggctt gattcatttt
    19801 gatgtggaaa aaagctttaa aagtcgcgat gataatttca acaaggtcaa ggatttccac
    19861 cgcctgatgg acggagacac gattgaaaca ccaagaggct attccttaaa ggaggctggc
    19921 tatcgagcag attttaaggt agaggaactt gtggaatttc tttatgcagc cagtcaaggg
    19981 gataagcatc gcttttctca ggctttgata gacctccatg ctgcccttga taaggcagct
    20041 aagaaggtgc aggccaagga gcacccagag tcacccctgg ttgggcaggt tgatgctttg
    20101 acagatctgc tttattttac ctatggctca tttgtattga tgggagtgga ccctcagccc
    20161 atttttgaga ccgtccatga agccaatatg gggaaaattt tccctgatgg gaaagcgcat
    20221 tttgatccca taacgcataa aattcaaaag ccagatgact ggcaggagcg ctatgcacca
    20281 gagtcagcca tcaaaaaaga gttggacaag cagcttcaaa aatcattgca gcgcttggaa
    20341 aaataaggct gtctttattt tagaggcatt aaaaagcacc ttgagctgtg agttgatctc
    20401 ctagctgtta agcatttggc ctaacacttg gggtcacttc acttattagc tcagggtgct
    20461 ttttgatgta gactagacac cctcaataaa agggccctta agtctagcta gtggtaatta
    20521 gtatatgaga gcagtagtcc tttagtagcc ttgtgagctg aggctaaggg ctaggtatgg
    20581 ttacttcact taggctgcaa atgcttctga cagctgagag aattcgtctt gctacagggt
    20641 tttgtcatgc tctcgaacca ctaataggtc aaccttggca tgacgaagga tatattcaga
    20701 tgatgatcca atcagcaacc gctcaaaggt gttaagccca gttgccccaa ccataatcaa
    20761 atcaacctct tctttgtcag ggatatcgtg cgctaatagc gttttgggat tgccaaattc
    20821 aatcacctgc ttgacctcag tcagccctgc ctcgcgtgct tgtttttcaa aatcccccaa
    20881 gacctcttta gc
//
LOCUS       DARYYD010000035        20403 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.035, whole genome shotgun sequence.
ACCESSION   DARYYD010000035 DARYYD010000000
VERSION     DARYYD010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20403)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20403)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20403
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.035"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(85..1350)
                     /locus_tag="TV188_001305"
     CDS             complement(85..1350)
                     /locus_tag="TV188_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HEL1534656.1"
                     /translation="MAEFHFDIDQIANNAITKTDKTTDIITKLPTNTTGQISFYEKLS
                     PEQQQAITAKAPALVDTFMEDQNALLDFGQAAVEGVNATVNHILAEQKKLQIPQVDEL
                     LKNTNRELNGFIAKYKEATAAELEKKPTLLQKLFKQSKNTLQEFYFDSQTIEQKMDGM
                     AAAVVKQEDTLARNIVAAELLIEDNTKSIENLVGVIAFLEASQKETSSRALTLQQELA
                     VLDTTTPEYQVQSDLLARTTEVLNTLEQQHTEYLSRLYVAWATTPQMRNLVKVSSDMR
                     QKLGMLRRNTIPTMKLSIAQLGIMQQSVKSGMTADAIVNANNAALQMLAETSKEAIPN
                     LERTAQSPTISLTSVTALAESLVAQNNGIIAAIDQGRKERAQLEAAIIKSAETINDSV
                     KLRDQSIIQALLNEGKEKQETIEQTERQP"
     gene            complement(1364..2221)
                     /locus_tag="TV188_001306"
     CDS             complement(1364..2221)
                     /locus_tag="TV188_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534657.1"
                     /translation="MSRKYYQVSRRRKGFSWFGWLIGFAILVGVVENIDKAVLIFAAL
                     GVGYAAYRYSNRQARLKTATLEKRLEDLKATIQLADRKVKLLDHYLAKEDFTQYAILA
                     KQLLPQLSEIKKESGHLKEHMDISIYRRVTKKANDVESDVQLQLEKIQIAANLKAESL
                     KEQAADPIYKAPELRHYYDNIQADHHSILEKIKGADNHEELLALHEANMRRFQDILQG
                     YLKIKETPKNYYNADERLQQALEAIQQFDLDLDETLRKLNESELKDFDVSLRMMKGSA
                     QASEANTTN"
     gene            2564..3856
                     /locus_tag="TV188_001307"
     CDS             2564..3856
                     /locus_tag="TV188_001307"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEL1534658.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSSDAEVIARYQGGDNAGHTIV
                     IDNKKFKLHLIPSGIFFPEKISVIGNGVVVNPKSLVKELAYLHEEGVTTDNLRISDRA
                     HVILPYHIKLDQLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDRDIFAERL
                     KTNLAEKNRLFEKMYDSAPIAFDEIFEEYYAYGQEIKKYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREIGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLETVKICVAYDLDGKRIDHYPASLEQLKRCKPIYEELPGWSEDITGVRSLEDLPEN
                     ARNYVRRIGELVGVRISTFSVGPGREQTNILESVWATI"
     gene            complement(3971..4744)
                     /locus_tag="TV188_001308"
     CDS             complement(3971..4744)
                     /locus_tag="TV188_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEL1534659.1"
                     /translation="MTTKGIVFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCANPESQK
                     TLPEKMLSTDGLKTEIVGQEKTVEEIIAEVLKDLDFYEESGGGMTLSGGEIFAQFDFA
                     LALLKAAKAEGLHTAIETTAFAKHEQFAELINYVDFIYTDLKHYNRLKHTKVTGVRND
                     LIIKNIHYAFEMGKEVVLRIPVIPNFNDSLEDAKAFSELFNQLNINQVQLLPFHQFGE
                     NKYKLLGRSYDMADAVAYHPEDLVDYQQIFLNHHIHCYF"
     gene            4869..5615
                     /locus_tag="TV188_001309"
     CDS             4869..5615
                     /locus_tag="TV188_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEL1534660.1"
                     /translation="MNRLEKIIQLVFQKKKIDVNTLSEQLQVSKVTIRKDLDKLESKG
                     LLRRVHGYAVLNSGDDLNVRLSYNYNIKRRIAEKAAELVQDNDTIMIESGSTCALLAE
                     VLCQTKQNIKIITNSCFIASYIRQYSSCQLILLGGYYQPNSEVTVGPLLKEMISLFHV
                     DRVFVGTDGFDPAIGFMGKDMMRSEGVRYMAEASEELIILTDSSKLSKPSLVHQLSLE
                     AVDRMITDEQLEASTYKLLQEHGIAIDFIS"
     gene            5630..6610
                     /locus_tag="TV188_001310"
     CDS             5630..6610
                     /locus_tag="TV188_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEL1534661.1"
                     /translation="MKEGRKRLLAKVAYLHYVQGKSQTAISKQMNIYRTTVCRMLAKA
                     RAEGIVRIEIADYDANLFALEEYVRQKYGLEKLDIVSNQMEDSPSDTLVKVAKTAAEV
                     LRSTVKDGDKIGLSWGATLSSLIDELDPKVMKDIMVCPLAGGPSHINAKFHVNTLVYR
                     LARIFHGNSSFINAMVVQKDKQLTRGILQSKYFEETLTYWNHLDLALVGIGGEPNGHQ
                     TSQWRDLLTDKDYKQLADDKAVGEVCCRFFDQEGHSVHQELQDRTIGISLEQLARVPK
                     TIAVAVGQAKAKAILAALKAKFINYLITDKATIMAVLALDQDQTADTYLS"
     gene            6849..7169
                     /locus_tag="TV188_001311"
     CDS             6849..7169
                     /locus_tag="TV188_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEL1534662.1"
                     /translation="MELIVPDQIIMGLILNAGDAKQHIYQALKLAKAKDYEASDKELA
                     LADDALLEAHNLQTQFLAQEASGAKADITALFVHSQDHLMTTITEINFIKEIIELRKE
                     LAEN"
     gene            7194..7502
                     /locus_tag="TV188_001312"
     CDS             7194..7502
                     /locus_tag="TV188_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEL1534663.1"
                     /translation="MIKIGLFCAAGFSTGMLVNNMKVAAEKKGIACEIEAYSQGKLAD
                     YAPAIDVALLGPQVAYTLDKSEVICKENGIPIAVIPMADYGMLDGDKVLDLALSLIKE
                     "
     gene            7513..8817
                     /locus_tag="TV188_001313"
     CDS             7513..8817
                     /locus_tag="TV188_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEL1534664.1"
                     /translation="MANMNAQKIIAPIMRFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     AGQIPFQGVNDAIASVLGADWTEPFMQVYQGTFAIMGLISCFSIGYSYAKNSGVEPLP
                     AGVLSLSAFFILLRSSYVPKKGEAIGDAISKAWFGGQGIIGAIIIGLVVGAIYTAFIR
                     RHIVIKMPEQVPWAIAKQFEAMIPAFAIFILSMLVYIIAKLVTGGGTFIEMIYAVIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGIVTALLLSNLDANKALLAAGDLS
                     LAKGAHIVTQQFLDSFLILSGSGITFGLVIAMIFAAKSKQYKALGKVAAFPALFNVNE
                     PVVFGFPIVMNPVMFLPFILVPVVAALIVYGSIAIGFMQPFAGVTLPWSTPAIISGFM
                     VGGWQGALVQALILVLSTVIYFPFFKVQDNIAYQNELAAEKA"
     gene            9098..11515
                     /locus_tag="TV188_001314"
     CDS             9098..11515
                     /locus_tag="TV188_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEL1534665.1"
                     /translation="MTEAKNPYFGTLTERMHRYREAVLDKKPYIDAERAILATEAYQK
                     HQNKPSNLKRAYMLQNILENMTIYIEDESLIAGNQASSNKDAPIFPEYTLEFVLNELD
                     LFEKRDGDVFYITEETKQQLRELAPFWENNNLRARCGVLLPKEVQVYMETGFFGMEGK
                     MNSGDAHLAVNYQKLLEVGLKGFEERTRAAKAALDLTIPESIDKYHFYDSVLIVIAAV
                     KAYAERYAKLARELAKTANPERQAELLEIARICDKVPYQPAETFAEAVQSVWFIQCIL
                     QIESNGHSLSYGRFDQYMYPYAKADLEAGRETEDSIVERLINLWIKTLTINKVRSQAH
                     TFSSAGSPLYQNVTIGGQTRDKQDAVNPLSYLVLRSVAQTKLPQPNLTVRYHKGLDNR
                     FMNECIEVMKLGFGMPAMNNDEIIIPSFIKKGVLEEDAYDYSAIGCVETAVPGKWGYR
                     CTGMSYINFPKILLITMNDGIDPASGKRFATGHGHFKDMTSYDELKAAWDATLREITR
                     MSVIVENAIDLGLEREVPDILCSALTDDCIGRGKTLKEGGAVYDYISGLQVGIANLSD
                     SLAALKKLVFEEGRLTTDELWHALETDFAGERGEEIRQMLINDAPKYGNDDDYADSLV
                     VEAYDTYIDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGKGTLATPDGRHAGTPL
                     AEGCSPEHSMDKKGPTSVLKSVAKLPTDEIVGGVLLNQKVNPQTLAKEEDKMKLMALL
                     RTFFNRLHGYHIQYNVVSRETLIDAQKNPEKHRDLIVRVAGYSAFFNVLSKATQDDII
                     ERTEHTL"
     gene            11530..12198
                     /locus_tag="TV188_001315"
     CDS             11530..12198
                     /locus_tag="TV188_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEL1534666.1"
                     /translation="MEYMLDTLNLEAIKKWNRILPLAGVTSNPSIAKKEGDIDFFERI
                     REVRAIIGDKASIHVQVVAQDYEGILKDAAAIRQQCGDSIYVKVPVTTEGLTAIKTLK
                     VEGYHITATAIYTTFQGLLAIEAGADYLAPYYNRMENLNIDPEAVIGQLAEAIDRECS
                     DSKILAASFKNVAQVNRAFALGAQAITAGPDVFEAGFAMPSIQKAVDDFGKDWQAIHH
                     RQTI"
     gene            12323..13414
                     /locus_tag="TV188_001316"
     CDS             12323..13414
                     /locus_tag="TV188_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEL1534667.1"
                     /translation="MKVFASPSRYIQGKNALFTNSDIIKKLGQKPVLLCDDIVYGIVG
                     ERFEGYLSEHGLPPVHVAFNGEASDNEINRVVAIARENDNDVIIGLGGGKTIDSAKAI
                     ADILEIPVIIAPTIASTDAPTSALSVIYTDEGAFEKYIFYAKNPELVLVDTQVICQAP
                     KRLLASGIADGLATWVEARAVMQKNGDTMAGGNQTLAGLAIAEACERTLFADGLKAMA
                     SCEKKVVTPALENVIEANTLLSGLGFESAGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLTQLFLENKSREEIDRYVDFYQAIGMPTTLKEMHLDTATEEDFLKIGRQATMAGE
                     TIHQMPFTITAEDVASALVAVDAYVCSRT"
     gene            13921..14973
                     /locus_tag="TV188_001317"
     CDS             13921..14973
                     /locus_tag="TV188_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEL1534668.1"
                     /translation="MIRKIGIVSLSSGMLGEANVKHELDLGLARLKQLGLEVTILPNA
                     LKGIDYFDQHPEARAADMIQAFADPSIDMILCAIGGVDTYRLLPYLFIEHQLQDVVNQ
                     KVFLGFSDTTINHLMLHKLGIKTFYGQSFLADICELADDMLPYSLAYFKELLETGTIA
                     EIRPSEKWYEERTDFSANSLGTQRIAHRNQGFELLKGPSLFKGEILGGCLESLYKLLD
                     SSKCSDSAKLCEQYQLFPDLSDWAGRLLLLETSEDKSDPAQYRRMLETLKATGIFSVI
                     SGLLVGKPIDNSYYDDYKQQLLAVVDNDIPILYNVNVGHATPRAIVPFGVMAVVDAKE
                     QVIRFVPDEHTDQNDV"
     gene            15002..15580
                     /locus_tag="TV188_001318"
     CDS             15002..15580
                     /locus_tag="TV188_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1534669.1"
                     /translation="MPKVDTITQVYFIRHAEPNYQNHNDVTRELSEHGVKASQDLVRQ
                     LAEVSIDAFYSSPYKRSIDTIAPLAASRAMEIKLIDDLRERKLADAWIEDFVDTAKKQ
                     WDDFTFKLPTGESLQEVQDRNIAALNRILKEAKGKTVVIGTHGTALSTLINYYQPDFG
                     FEDFDRYKHVFPWIVRASFDGDKLLGLNEFLV"
     gene            15779..16687
                     /locus_tag="TV188_001319"
     CDS             15779..16687
                     /locus_tag="TV188_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1534670.1"
                     /translation="MTNKTKRTGLVRKYGACSAAIALAALASLGAGKAVKADQPAALK
                     YPEPRDYFLHTREGDVIYDEDIKRYFEDLEAYLTARLGGIDKKVEEAAQKPGIPGPTG
                     PQGPKGDKGDPGAPGERGPAGPKGDTGEAGPRGEQGPAGQAGERGPKGDPGAPGPKGE
                     KGDTGAVGPKGEKGDTGATGPKGDKGERGEKGEQGQRGEKGEQGQRGEKGEQKPKGDQ
                     GKDTKPSAPKAPEKAPAPKAPKASEQSSNPKAPAPKSAPSKSAAPTGQKAALPATGEI
                     NHPFFTLAALSVIASVGVLTLKGKKD"
     gene            complement(16923..18269)
                     /locus_tag="TV188_001320"
     CDS             complement(16923..18269)
                     /locus_tag="TV188_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1534671.1"
                     /translation="MKKNQVTRYSLLIPAALMAAGLAMSTNSSVAFADESPAVDNHTV
                     VQPRLGEDKDTADTANQQLSDSTEVMADKPITKASETANPVAAADKLPLDTNQSAEDI
                     IAVKKAYIAKNTGLPLDKIQLLDTSEGKALMYPHDDHHHVILLDKIDVSKPFDDGQSS
                     HHSDHAHHHHDDVIEGSFAFTATVIDPEGKVLSGKDVQVVDITSGRKTLATVTTDEKG
                     QAVFDKLPLGRSLSIFVNGVPQGYTVRTGVDGDKHSASFTVDGKGTVEPEYSKTPLVV
                     IVRNEDAEPLSGQEVTLKHRVGRVIEKVTTGADGKAVFSKGLLDGTFYEIFVNGKKLS
                     QATTGEERSVALDAKDIKKSSPHSKPQEDAPKVPETKPETKPEAKPLSPEKADQAGKV
                     AAPAHTASKAAAAKAEMKKTTNQLPATGEAVNPFFTAAALAVMATAGVAAIKRKEN"
     gene            complement(19309..19413)
                     /locus_tag="TV188_001321"
     CDS             complement(19309..19413)
                     /locus_tag="TV188_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019773529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1534672.1"
                     /translation="MTAFEVVQILLGFSSFTIALISLCYQIFKDDNKK"
     gene            complement(19793..20308)
                     /locus_tag="TV188_001322"
     CDS             complement(19793..20308)
                     /locus_tag="TV188_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEL1534673.1"
                     /translation="MKIVIIGYSGSGKSTLANVLGQHYNCAVLHLDKIHFASNWQERT
                     VSQMVSDISTFMSQKHWIIEGNYSSCLYEERMREADHIIYFNFNRFNCFYRAFKRYLK
                     YRGQTRPDMAENCNEKFDVEFMKWILLDGRSKNNLNNYKAVIKQYPHKTIVLKNQKQL
                     NHYMNSIQHDS"
BASE COUNT         5781 a         4094 c         4555 g         5973 t
ORIGIN      
        1 tgacagaagg gtatttttga ttgttaccaa tcaaaaagcc acaggctggg tagctgtggc
       61 aggtctgtta tatcaggagc tgctttaagg ctggcgttct gtctgctcga ttgtctcctg
      121 cttttctttg ccctcattga ggagagcttg aatgatgctt tggtcgcgca gcttgacaga
      181 atcattaatg gtttctgctg atttgataat ggctgcttcc agctgagctc gctccttgcg
      241 tccttgatca atggcagcaa tgatgccgtt gttctgggca actagacttt ctgctagtgc
      301 tgtcactgag gtcaacgaaa tcgttgggct ttgagctgtc cgctcaaggt ttggaatcgc
      361 ttccttgctt gtctcagcta gcatttgtag ggcagcgttg ttggcattga caatggcgtc
      421 tgcggtcatt ccagacttga cagactgctg catgatacct agctgagcaa tagataattt
      481 catggttgga atggtattgc gtcgcagcat gcctagcttt tgtcgcatgt cagaggacac
      541 cttgacgagg ttacgcattt gcggtgttgt tgcccaagcc acatagagtc gactaaggta
      601 ttcggtgtgc tgctgctcaa gggtattgag cacctctgtt gtcctagcca ataggtcaga
      661 ttgcacctga tactctggtg ttgtcgtgtc aagtactgca agctcctgct gcaaggtaag
      721 ggcgcggcta gaggtttcct tttgactagc ttcaagaaag gcaatcacac caaccagatt
      781 ttcaatcgac ttggtattgt cctcaatcaa gagctctgcg gctacaatat tacgagcaag
      841 cgtgtcttct tgcttgacaa cagctgcagc cataccgtcc attttttgct caatggtctg
      901 agaatcaaag taaaattcct gaagcgtgtt cttgctttgt ttgaatagct tttgcaaaag
      961 cgttggcttt ttttcaagct cagcagcggt cgcttcctta tatttggcaa taaaaccatt
     1021 aagctcacga ttggtgtttt tgaggagctc gtcaacctgt ggaatttgta atttcttttg
     1081 ctcagctaga atatgattaa cagtagcatt aactccttca acggctgctt gaccaaaatc
     1141 aagtaaggca ttttggtcct ccataaaggt atcaacaagt gctggtgcct ttgcagtgat
     1201 agcctgctgc tgctcaggac tcagcttttc gtagaaagaa atttgtccag tagtattggt
     1261 tggtagctta gtgataatat cggtggtttt atctgtttta gtgatagcat tattagcgat
     1321 ctggtcaata tcaaagtgaa attctgccat aatagctcct ttatcagttg gtagtgttag
     1381 cctcgctagc ttgagcagag cccttcatca tgcgcagact aacatcaaaa tcctttagct
     1441 cactttcgtt aagcttcctt agggtctcat caaggtccag gtcaaattgt tggatagcct
     1501 caagagcctg ctgcaagcgc tcatcagcat tgtaataatt tttaggtgtt tctttgattt
     1561 ttaggtagcc ctgcaaaatg tcttgaaacc tgcgcatatt agcctcatgg agtgctaaga
     1621 gttcctcgtg attatcagct cccttgattt tttctaaaat cgagtggtgg tcagcctgga
     1681 tattgtcata atagtgacgt agctcgggcg ccttataaat ggggtcagct gcctgctcct
     1741 ttaggctttc agccttcaga tttgctgcga tttgaatctt ttcgagctgt agctgcacat
     1801 cgctttccac gtcattagcc tttttggtca cacgacggta aatgctaata tccatgtgtt
     1861 ccttgaggtg accgctttct tttttgattt cactcaattg cggcagtagc tgcttggcta
     1921 aaatggcata ctgtgtaaaa tcttccttag ccagataatg atcaaggagc ttaacctttc
     1981 ggtcggcaag ctgaatagtt gcctttaaat cctccaagcg tttctcaagt gttgccgttt
     2041 ttaagcgagc ctgacggttc gaatagcgat aagcagcata accaacaccc agcgctgcaa
     2101 aaatcagaac agctttgtca atattttcta caactcctac taaaatcgcg aagcctatca
     2161 gccagccaaa ccagctaaag ccctttcttc gtcgagatac ttggtaatat tttcgtgaca
     2221 tgtaaaactt cctttgtact ttttatcaca gtaaacaatc aattagttct attttacctt
     2281 aaaaatgtga tttcttaaag gaaagattag cagatttagc attattttcc ttcaaagact
     2341 ggtcttgctt gctttttagt gaaatgtttg ctttctgcct gttttcagaa aaaagcattt
     2401 gccatttgat attttttctt aataatacca aggaaagata gcagaaaacc acattttttg
     2461 ctataatgag gtgtaacaga cacttgcagg tgagagtcct gccacattta tcaagaaagg
     2521 tgggggctct ctttctttgt tgagatgagc ctatatcgaa gatatgacat cagtagtagt
     2581 agttggtacc cagtggggtg acgaaggtaa gggtaagatc actgactttt tatcctcaga
     2641 tgcagaagtg attgcacgtt accaaggtgg tgacaatgca ggacatacca ttgttattga
     2701 taacaagaaa ttcaagctgc acctgattcc atcaggtatt ttcttcccag aaaagatttc
     2761 tgtgattgga aatggtgtgg ttgtcaatcc aaaatccttg gttaaggagc ttgcttacct
     2821 gcatgaggag ggcgtgacca cagacaattt gcgcatttct gatcgtgctc atgtcatttt
     2881 gccataccat atcaagcttg accagcttca agaggaagca aagggtgaca ataaaatcgg
     2941 taccaccatc aagggcatcg gtccagccta tatggataag gcagcacgtg ttggtatccg
     3001 tattgcagac ctgttagaca gggatatttt tgctgagcgc ttaaagacga atctggctga
     3061 gaaaaatcgt ctttttgaga aaatgtatga cagcgcaccg attgcatttg acgagatttt
     3121 tgaagaatac tatgcttatg gtcaagagat caaaaaatat gtgacagaca catctgttat
     3181 tttgaacgac gctcttgatg cgggcaagcg tgtccttttt gagggagctc aaggggttat
     3241 gcttgatatt gatcagggaa cctatccatt tgtcacctca tctaatccag ttgcaggcgg
     3301 tgtgaccatt ggttcaggag tcggaccaag caaaatcaac aaggttgttg gagtatgtaa
     3361 ggcctatact agtcgcgttg gtgatggacc attccctacc gagttatttg acgaggttgg
     3421 tgagcgcatt cgtgagattg gtcatgagta tggaacaacc actggtcgtc cacgtcgcgt
     3481 tggctggttt gattctgttg tgatgcgtca tagccgtcgt gtgtcaggca ttaccaatct
     3541 atcacttaac tctattgatg tgctatcagg ccttgagact gtaaaaatct gtgtcgctta
     3601 tgaccttgat ggtaagcgca ttgatcatta cccagcaagc cttgagcagc taaaacgctg
     3661 caaaccgatt tatgaagagc ttccaggctg gtcagaggat attaccggtg ttcgcagcct
     3721 tgaggatctc ccagaaaatg ctcgcaacta tgttcgtcgt attggcgaac tggttggtgt
     3781 tcgtatctca accttctcag taggtccagg acgtgagcaa accaatatcc ttgaatctgt
     3841 ttgggcaact atctaagctg tctattgtga tagcaccagc cttagctgaa tattaacgaa
     3901 aacacgagca atcctaagga aggttatccg gaggagctgc tcatgttttt taggtatagg
     3961 gcttttaaga ttaaaaatag caatggatat gatgattgag aaagatttgc tgataatcca
     4021 ccagatcctc tgggtgataa gcgacagcat cagccatgtc atagcttctg cctagcaatt
     4081 tgtatttgtt ttcaccaaac tggtgaaagg gaagtagctg cacctgatta atgtttagct
     4141 gattgaaaag ctcagaaaat gccttggcgt cctccaaaga atcgttgaaa ttcggaatga
     4201 cagggatacg caagacgact tccttgccca tctcaaaggc gtagtggata tttttaatga
     4261 tcaggtcatt tcgcaccccg gtgaccttgg tgtgctttag gcgattatag tgcttcaaat
     4321 cggtataaat aaagtctaca tagttgatca gctcagcaaa ttgctcgtgc ttagcaaagg
     4381 ctgtcgtttc gatagctgtg tgtagccctt ctgccttagc agcctttaga agcgctaagg
     4441 caaagtcaaa ttgagcaaag atttcaccgc cagacaaggt cataccaccg ccagattcct
     4501 cgtaaaaatc aagatccttt aaaacctcag caataatctc ttcaaccgtc ttttcctgac
     4561 caacgatttc tgtctttagt ccatctgtgc ttagcatttt ttcgggtaac gttttttgtg
     4621 attcgggatt ggcacaccag ggacagcgta agggacaccc cttgagaaat acagttgtgc
     4681 gaatgcctgg tccatcgtgt atgctaaaat gctggatatt aaatacaatg ccttttgtcg
     4741 tcatagcgag acttcctttc gttctaggac tatcataaca gataaacgta aataaatcaa
     4801 ttacgaacga aagttatttt tgcttttcat ttaccgccat aattgttaca atggaaagga
     4861 ggtaaattat gaatcgttta gaaaaaatta tccaattagt atttcaaaag aaaaaaatag
     4921 atgttaatac tttatctgag cagctacagg tctccaaggt aaccattcgt aaggatttag
     4981 acaagcttga aagtaagggg ctgctgcgtc gtgtgcatgg ctatgcggtg ctcaatagtg
     5041 gtgatgattt gaatgtgcgc ctgtcctata attataacat caaaaggcgg attgctgaaa
     5101 aggctgccga gctggtgcag gacaacgata ctatcatgat tgagtcagga tcgacctgtg
     5161 ccctgttggc agaggtgctc tgtcaaacca aacaaaacat caaaatcatc accaactcct
     5221 gctttattgc aagctacatt cgtcagtata gtagctgtca gcttatcctg ctggggggct
     5281 actatcagcc taattctgag gtgaccgtag gcccactttt aaaggaaatg atttcgcttt
     5341 ttcatgtgga tcgtgttttt gttgggacag atggctttga tccggcaatt ggctttatgg
     5401 ggaaggatat gatgcgctca gagggcgtcc gttacatggc agaggcttct gaggagctta
     5461 ttatcctgac agattctagc aagcttagca aacccagtct ggttcatcag ctatcgcttg
     5521 aggctgttga ccgtatgatc acagatgagc aattggaggc aagcacctat aagctcctgc
     5581 aagagcatgg tattgccatt gactttatat cgtagcgtag ggaactcaaa tgaaagaagg
     5641 acgtaaacgc ctgcttgcca aggttgccta cctgcattat gtgcagggca aaagccaaac
     5701 cgctatttca aagcaaatga atatttaccg aacaacggtc tgtcgcatgc ttgccaaggc
     5761 tagggctgaa ggcattgtgc gtatcgagat agctgattat gatgctaatt tgtttgcctt
     5821 ggaggagtat gttcgtcaaa aatatggctt agaaaagctt gatattgtat ccaatcaaat
     5881 ggaagatagc cctagtgata ccttggtaaa ggtggccaaa acagcagccg aggttttgcg
     5941 cagtacggtc aaggatggtg ataagattgg cttatcgtgg ggggcaacgc tgtcaagtct
     6001 gattgacgag ctggatccta aagtaatgaa ggatattatg gtgtgtccct tggctggtgg
     6061 tcctagtcat atcaatgcca agtttcatgt gaatactctg gtttatcgct tagcaaggat
     6121 ctttcatggc aatagctcct ttatcaatgc tatggtggtt cagaaggaca agcagctaac
     6181 cagagggatt ttgcagtcca agtattttga agaaaccctg acctattgga accatcttga
     6241 ccttgctctg gtcggtattg gaggagagcc aaatggtcat cagaccagtc agtggcgtga
     6301 tttgttgact gataaggact ataagcagct ggcagatgac aaagctgttg gtgaggtctg
     6361 ctgtcgcttt tttgatcagg aggggcatag tgttcatcag gaattgcaag acagaacgat
     6421 aggcatttca ctggaacagc tcgcgcgtgt gcctaagaca atagctgttg ctgttggtca
     6481 agctaaggcc aaggctattt tagcggcttt aaaggctaaa tttatcaatt acctcatcac
     6541 cgataaggct actatcatgg ctgtcttggc tttggatcag gatcagacag ctgacaccta
     6601 tctctcatag caatagctta atcagaagac gattgttttc tgattttttt gtgaccaaaa
     6661 atcttgcaaa gcatcacttt tgcacaatag tgctaaaaaa taaatacagc acacaatata
     6721 ttgacgaagg aagtaaaaat gataaaatga acttatcaaa gaaatgtaaa cgattacaaa
     6781 cgcaagctgt ttttttacga aaaaagcaag ggtaatcctt acatgagcac gtcacaaagg
     6841 agaaacaaat ggaattaatt gtaccagacc aaatcatcat ggggttaatc ctaaatgcag
     6901 gagatgcaaa gcagcatatc tatcaagccc taaagctggc taaggctaaa gactatgagg
     6961 ctagtgacaa ggagttagcc ttagctgatg atgctttatt agaggcgcat aatttgcaga
     7021 cacaattttt agctcaggag gctagcgggg caaaggcaga cattacagcc ttgtttgtcc
     7081 attctcagga tcacttgatg acaactatta cagaaatcaa ttttatcaaa gaaatcattg
     7141 agcttcgtaa ggaattagca gaaaactaaa gatcatatca aaaggaggac gttatgatta
     7201 aaattggctt attttgtgca gcaggctttt caacaggcat gcttgtgaac aacatgaagg
     7261 tggctgctga gaaaaagggc attgcttgtg agattgaagc ctactcacaa ggaaagctgg
     7321 cagactatgc accagctatt gatgttgccc tcttaggtcc acaggtggct tataccttgg
     7381 ataagtcaga ggttatctgt aaggaaaacg gcattccaat agctgttatc ccaatggctg
     7441 attatggtat gctagatggt gataaggtgc ttgacttagc gctcagcttg ataaaggaat
     7501 aggagcttgg tcatggctaa tatgaatgct caaaaaatca ttgcaccgat tatgcggttt
     7561 gttaatatgc gtggcattat cgctctaaag gacggtatgc tggcgatttt acccttgacg
     7621 gttgtcggaa gtctttttct tattgcaggt cagattccct ttcagggggt caatgacgct
     7681 atagcgagtg tccttggggc agactggaca gagccattta tgcaggttta tcagggtacc
     7741 tttgctatta tgggcttgat ttcctgcttt tcgattggct attcctacgc taaaaattcg
     7801 ggtgtggagc cactgccagc aggtgtgcta tcattgtcag ccttctttat cctgctaagg
     7861 tcctcttatg tgccaaaaaa gggtgaggct attggtgatg ccattagtaa ggcttggttt
     7921 ggtggtcaag ggattattgg tgccatcatt attggcttgg tggttggtgc gatttataca
     7981 gcctttattc gtcgtcatat cgtcatcaaa atgccagagc aggtgccgtg ggccattgcc
     8041 aagcaatttg aagcgatgat tccagccttt gcaatcttta tcctgtcaat gcttgtttat
     8101 atcattgcaa agctagtgac aggtggcggc acctttattg aaatgattta cgctgtgatt
     8161 caggtgcctc tacagggctt gactggctct ctttacggtg cgattggtat tgcctttttc
     8221 atctccttcc tatggtggtt tggtgtgcat gggcaatcag tggtcaatgg tatcgtgaca
     8281 gcgctgctct tgtcaaatct agatgctaac aaggccttgt tagcagcagg tgatttgtct
     8341 ttggctaagg gtgctcatat tgtgacgcag caatttttag attctttctt aattttatca
     8401 ggctcaggta ttacctttgg cttagtgatt gccatgattt ttgcagccaa atcaaagcag
     8461 tacaaggctc taggcaaggt agcagccttt ccggctctct ttaatgttaa tgaaccggta
     8521 gtctttggct ttccaattgt gatgaaccca gtgatgtttc tgccatttat tttggtgcca
     8581 gttgttgcgg ctctgattgt ttatggctct attgcgattg ggtttatgca gccatttgca
     8641 ggtgtaacac ttccttggtc tacaccggct attatctcag gctttatggt tggtggctgg
     8701 cagggggctc ttgttcaggc tttgattctt gtcttgtcaa ccgttattta cttcccattc
     8761 tttaaggttc aggataatat tgcttatcaa aatgaattgg cagctgaaaa agcttaacag
     8821 tatgctgata tcaatcacca tgacttaaaa acagtcttta gtcactagct atagcattcc
     8881 tagagaaggg cttagagaag gaggatttct tcacgtaacc atctcaatga ggtggttttt
     8941 ttgaaagaga ctcttagaca agtctatttt tgcacgatag tgcaacttta aatgaatagc
     9001 tgaatgctat ggatatgata ggcaaaatgt tttaaatatg gtaaaataat tacgaaagaa
     9061 agtaatttaa tttcgtaaga aacaaaggag gcctaatatg actgaagcaa agaatcccta
     9121 ttttggtaca ttaacagaaa gaatgcaccg ctatcgtgag gcagttctag ataaaaagcc
     9181 ttatattgat gctgagcgtg ctattttagc aacagaggct taccaaaaac accaaaacaa
     9241 gccatctaat ctaaaacgcg cttacatgct gcaaaatatt ttggaaaaca tgaccatcta
     9301 cattgaggac gaaagcttga ttgctggtaa tcaggcgtct tctaacaagg atgcacctat
     9361 ctttccagag tacactcttg aatttgtcct aaatgagctt gacctttttg aaaagcgtga
     9421 tggcgatgtg ttttacatca ctgaagaaac caagcagcag cttcgcgagc ttgcaccctt
     9481 ctgggaaaat aacaatttgc gggcccgctg tggtgtcttg ctgccgaaag aggttcaggt
     9541 ttatatggaa actggcttct ttggcatgga aggcaagatg aattcaggag atgcccattt
     9601 agctgtcaat taccaaaagc tattagaggt tggcttgaag ggctttgagg aacggactcg
     9661 tgctgccaag gctgcgcttg atttgactat tcctgaaagc attgataagt accattttta
     9721 tgattctgtt ctgattgtga ttgctgcggt taaggcttat gcagagcgct atgccaaatt
     9781 ggcgcgtgag ctggccaaaa cagctaatcc agagcgtcag gcagaattgc ttgaaatcgc
     9841 gcgtatctgt gacaaggtgc cttaccagcc ggcggaaacc tttgctgaag cggtccaatc
     9901 agtttggttt atccagtgta ttcttcagat tgagtcaaat gggcattctc tttcttatgg
     9961 ccgatttgat caatacatgt atccatatgc caaggctgat ttggaggctg gtcgtgaaac
    10021 agaggattct atcgttgagc gcttgattaa cctttggata aagactctga ccatcaataa
    10081 ggtacgcagt caggctcata ccttctcatc agcaggtagt ccgctgtatc aaaatgtcac
    10141 cattggtggg caaaccagag ataagcagga cgctgtaaat cctctatcct acctagtgct
    10201 tcgcagtgtg gctcaaacca aattaccaca accaaaccta accgttcgat atcacaaggg
    10261 cttggataat cgttttatga atgaatgcat tgaggttatg aagcttggct ttggtatgcc
    10321 agctatgaac aacgatgaaa tcatcattcc gtcctttatc aaaaagggtg tccttgaaga
    10381 agacgcctat gattattcag caattggctg cgttgagaca gccgttccag gtaaatgggg
    10441 ctatcgctgt actggtatga gctacattaa ctttccgaag attttgctta tcaccatgaa
    10501 tgatggtatt gacccagctt cgggtaagcg ctttgcaaca ggacatggtc acttcaagga
    10561 tatgacctct tatgacgagc taaaggcagc ttgggacgcg actctgcgtg aaatcactcg
    10621 catgagtgtc atcgtagaaa atgccattga ccttgggctt gaacgagagg tgccagacat
    10681 tctttgctct gcattgaccg atgattgtat cggccgaggc aagacgctca aagaaggtgg
    10741 agcagtctat gactacatct caggcttgca ggtggggatt gctaacctgt ctgattccct
    10801 agctgcactg aaaaaattgg tgtttgagga gggtcgccta accactgatg agctctggca
    10861 tgctctagaa acagactttg caggtgagcg tggtgaagag atccgtcaaa tgctgattaa
    10921 cgatgcacca aaatatggta atgatgatga ctatgctgat agcttagtgg ttgaagccta
    10981 tgatacctac attgatgaaa ttgctaaata ccctaatacg cgctacggac gtggtccgat
    11041 tggtggtatt cgctactcag gcacctcatc tatttcagct aatgtcggcc aaggtaaggg
    11101 aaccttagct accccagatg ggcgtcatgc aggaacaccg cttgctgagg gctgctcacc
    11161 agagcacagt atggataaaa aaggaccaac ttctgttttg aaatccgttg ccaaattgcc
    11221 aacagatgaa attgtaggtg gggtcttact caaccaaaag gttaatcctc agacactagc
    11281 aaaagaagaa gacaagatga agctgatggc tctgcttcgg accttcttta acaggctaca
    11341 tggctatcat attcaataca acgtcgtctc acgtgaaacg cttattgatg ctcaaaagaa
    11401 tcctgaaaag caccgcgact tgattgtgcg tgtggcaggc tattcagcct tctttaatgt
    11461 tttatcaaaa gccactcagg acgatatcat cgaacgtacc gaacacacac tataggagaa
    11521 caattactta tggaatacat gctagatact ctaaatctag aggctattaa aaagtggaat
    11581 cgcattttac cccttgcagg ggtaacctca aatccttcaa ttgctaaaaa agagggagat
    11641 attgattttt ttgaacgcat tagagaggtt cgtgcgatca ttggagataa ggcctctatt
    11701 catgtgcaag tcgtggcaca ggattatgaa ggtattttaa aggacgctgc ggctattcgt
    11761 cagcaatgtg gtgatagtat ttatgtaaag gttcctgtga caacagaggg actcacagcg
    11821 atcaaaaccc taaaggtaga gggctaccat atcacagcta cagccatcta tactaccttc
    11881 caaggcttac tggccatcga agcaggagca gattatctgg caccttacta caatcgcatg
    11941 gaaaacctca atattgatcc ggaggctgtg attggccagc tggcagaggc cattgatcgt
    12001 gaatgctctg atagtaaaat cttggcagcg agcttcaaaa atgtagctca ggtcaaccga
    12061 gcctttgctt tgggtgctca ggccatcact gctggtccag atgtctttga ggcaggcttt
    12121 gcgatgccat ctatccaaaa ggctgtagat gattttggca aggattggca agccattcat
    12181 catcgtcaaa ctatttaaaa gccatctaac ccatcgttat atgagcaaga gcagggacgc
    12241 ttctatcagc atagctagac tagtcttgct cactcttaga tggtgagaag cgtcaaaaat
    12301 ctgatttaga aagaggaaca tcatgaaagt atttgcaagt ccatcacgct atattcaagg
    12361 gaaaaatgcc ttatttacca atagtgacat catcaaaaag ctagggcaaa agccggtatt
    12421 gctctgtgat gatattgttt acggcattgt cggagaacgt tttgagggct atttaagtga
    12481 gcatggtcta ccacctgttc acgtagcctt taatggcgaa gcgtctgata atgagattaa
    12541 tcgtgtcgtt gccattgcta gagaaaatga taatgatgtc attatcggac ttggcggagg
    12601 caagaccatt gacagtgcca aggcaatcgc tgacatcttg gagataccag tgattatcgc
    12661 tccaaccatt gcctccactg atgctccaac atcagcccta tcagtgattt acacagatga
    12721 gggcgccttt gaaaaataca ttttctatgc taaaaatcct gagcttgtct tggttgatac
    12781 tcaggttatc tgtcaagcac caaagcgctt gctggcttca ggtattgctg atggtctagc
    12841 cacttgggta gaagcgcgtg cggttatgca aaaaaatggt gacacgatgg caggcggcaa
    12901 ccaaaccttg gcaggacttg ctattgctga ggcctgcgag cgtaccctgt ttgctgacgg
    12961 tctcaaggca atggctagct gtgagaaaaa ggtcgttact ccagctttag aaaatgtgat
    13021 tgaggctaat accttattaa gtggtcttgg ctttgaaagt gcaggacttg ctgctgctca
    13081 tgctattcac aatggcttta cagctttgac aggtgacatt catcacctca ctcatggtga
    13141 aaaggtggcc tatggcaccc taacacagct tttcctcgaa aataaatcaa gagaagaaat
    13201 tgaccgctac gttgactttt atcaggctat cggaatgccg acaaccctaa aagaaatgca
    13261 tttagacacc gccaccgaag aggatttctt aaaaataggg cgtcaagcaa ccatggcagg
    13321 agaaaccatt caccaaatgc catttaccat cacagcagag gacgttgcct cagcgcttgt
    13381 tgctgtagat gcttacgttt gcagcagaac ttaatgcaga actgctaaag ttctcttagc
    13441 cttatcagga gcctattgct ggtagctctt gaccaaagga ttgtacctac cttagcctta
    13501 attcaactgt tagaggtgtt cctcttgctg tggtaagaga ggttctttac tgctaaaggc
    13561 tcattctcag ggcaagctgg cccctccaaa tcatttaaaa agtcgtaaat ctaatcaata
    13621 atggctatca gtataggcta ctggtagtca ttattctata tctgatttat gagaacatac
    13681 cagtcagcag ctttgctgtg ccacctattt cttgtcatta cagtagctta gctttatagc
    13741 tgacagagca aatgcttcct catctattag ctcttaattc aaccgctaca gtaatagaaa
    13801 aagctaatca aagtaagggc tagttttttt tggtatcgct attaacagta tgtattagag
    13861 gctatcagcc tagccattat tgtggtataa tgacacaaca actttttaag gaggttagct
    13921 atgattcgga agattggtat tgtcagcttg tctagtggta tgcttggcga ggctaatgtc
    13981 aagcacgaat tggatttagg cttagcccgt ttaaaacagc taggcttaga ggtaacgata
    14041 ctcccaaatg ctttaaaggg catagactat tttgatcagc accctgaagc aagggcagca
    14101 gatatgattc aggcctttgc agatccgtct attgacatga ttttgtgtgc cattggtggg
    14161 gtggatacct atcgcctctt gccctatctg tttatcgaac atcagctaca agatgttgtc
    14221 aatcaaaagg tctttcttgg attttctgac accacgatca accacttgat gcttcataag
    14281 cttggtatta aaacctttta tggtcagtcc tttcttgccg atatttgtga gctggctgat
    14341 gacatgctgc cttactcgct ggcttatttt aaagagcttc ttgagacagg aactatcgct
    14401 gagatcagac ctagtgagaa gtggtatgag gagcggactg actttagtgc aaacagcctt
    14461 gggacacaga gaatagctca tcgcaatcaa ggctttgaac tattaaaagg tccgtcctta
    14521 ttcaagggag agatactagg tgggtgttta gagtcacttt ataaactatt ggattcgtca
    14581 aagtgttcag atagcgctaa gctctgtgag caataccagc tctttccaga tctgtctgac
    14641 tgggcaggca ggctcttgct tctagaaacc agtgaagaca agtcagatcc agctcaatac
    14701 cgccgaatgc ttgaaaccct caaagcaaca gggatttttt cggtgatctc tggattattg
    14761 gttggaaagc cgatagacaa cagctactat gacgactata agcagcagct gctagctgtt
    14821 gttgataatg atatccccat tctttacaat gtcaatgttg gccatgctac cccaagagcc
    14881 attgttccct ttggtgtcat ggctgtggtt gatgccaaag agcaggtcat tcgatttgtc
    14941 cctgatgagc atacagacca aaatgacgtc taacaaatca aaacagaaag tgagagagtc
    15001 tatgccaaag gttgacacga taacgcaggt ttattttatc cgccacgcag agcctaacta
    15061 tcaaaaccac aacgacgtga ctagagagct ctccgagcat ggggttaagg cgagccaaga
    15121 cctggttagg caactagcag aggtgtcgat tgacgccttt tattccagtc cctataaacg
    15181 ctctattgac accattgccc cactagcagc tagtagggca atggaaatta agctgattga
    15241 cgatttgaga gagcgtaagc tagctgatgc ttggatagaa gactttgtcg acacagccaa
    15301 aaagcagtgg gacgatttta cctttaaatt gccgacaggc gaaagcctgc aagaggtaca
    15361 agacagaaat atagcagctc ttaaccgtat tttaaaagaa gcaaaaggca agacagtagt
    15421 cattggcaca catggcacag cactgtcaac ccttatcaac tactatcaac cagactttgg
    15481 ttttgaggat ttcgaccgat ataagcatgt ctttccttgg atagtcagag ctagctttga
    15541 tggtgacaag ctgcttgggc ttaatgagtt tctagtctga caagtctagc cttgatccag
    15601 ctattatagg tgatgacagc aacaaaatca gataattaac cctttcatta aaaaaaaaaa
    15661 aaacaaaacc tcggagacaa actagccagc agctatttct catgagtaat caacatgtta
    15721 aaatcttctt tggagatatt agacaaccat aattattata tcatcaaagg agagaaagat
    15781 gacaaacaaa acaaagcgta caggattggt acgcaagtac ggtgcctgct cagcagctat
    15841 cgccttagca gctcttgcaa gcctgggagc aggtaaagca gtaaaggcag accagccagc
    15901 agcactaaaa tatccagaac ctagagacta ttttcttcat actcgtgaag gtgatgttat
    15961 ttatgatgag gatataaaaa gatattttga ggatttagaa gcctatttaa cagctagact
    16021 tggtgggatt gataaaaaag tagaagaagc tgcccaaaag ccaggtattc caggtcctac
    16081 tggccctcaa ggtcctaagg gagacaaagg agatccaggt gcccctggtg agcgcggtcc
    16141 agctggacca aagggcgata cgggcgaagc cggaccaaga ggtgagcaag gcccagccgg
    16201 acaagctgga gaacgtggac caaaaggaga tccaggtgct ccaggtccta aaggtgaaaa
    16261 gggtgatact ggtgcagttg gtcctaaagg tgaaaaaggt gataccggag caaccggacc
    16321 aaagggagac aagggcgaac gcggtgaaaa aggcgagcaa ggccaacgtg gcgaaaaagg
    16381 cgagcaaggc caacgcggtg aaaaaggcga gcaaaaacca aagggtgatc aaggaaaaga
    16441 tacaaaacca tcagctccaa aagcacctga aaaggctcct gcaccaaaag ctccaaaggc
    16501 ttcagagcag tcatctaatc ctaaagcacc agctcctaag tcagcaccaa gcaaatcagc
    16561 ggcaccaaca ggtcaaaaag cagccctacc agcaacaggg gaaatcaacc acccattctt
    16621 cacccttgca gctcttagtg tcatcgctag cgtaggcgtc ctaactctaa aaggaaaaaa
    16681 agactaagct agttattgta tctttcctgt atgacactag ctaacagcta atcacaaaca
    16741 ccagagagag gtcttttctg acctctcttt tatatacact gagcacatgc ttacctcaaa
    16801 aagacagtag tctaagtttg actactgtct caaaaatcat ttttatctaa agctttgatc
    16861 agcttgacaa atggtagaga aggacttgat ttctaaggcc tttgacctca gtttgacttt
    16921 tgttaatttt ccttacgttt tatagctgct acaccagctg tagccataac tgcaagtgca
    16981 gctgcggtga agaatgggtt cacagcctca cctgttgctg gcaattgatt agtcgttttc
    17041 ttcatctcag ctttagctgc tgctgcttta gaagctgtgt gagctggcgc tgctacttta
    17101 cctgcttgat cagctttttc aggactgagt ggtttagcct ctggcttagt ttctggtttg
    17161 gtttctggaa ctttaggtgc gtcttcttgt ggttttgaat gtggacttga ttttttaata
    17221 tctttagcat ctagggcaac gcttctttcc tcacctgttg tagcttgaga aagctttttg
    17281 ccgttgacaa aaatctcata gaaagtgcca tctagaagcc ctttagaaaa tacagctttg
    17341 ccatcagctc ctgttgttac tttctctatc acacgaccta ctctatgctt tagagtgact
    17401 tcttgtcctg ataaaggttc agcatcttca ttacgaacga taacaaccaa aggtgtttta
    17461 ctgtattctg gctcaactgt tccttttccg tcaacagtaa agctagctga atgcttgtcg
    17521 ccatcaacac ctgttcgtac agtatagcct tgaggaacgc cattcacaaa aattgataaa
    17581 cttcttccta aaggaagctt gtcaaaaaca gcttgtcctt tttcatctgt tgtcacagtc
    17641 gcaagtgttt ttctgccact tgttatatct accacttgga cgtcttttcc agataatact
    17701 ttaccctcag ggtctataac tgttgcggta aaagcaaagc taccttcaat aacatcatca
    17761 tgatggtggt gtgcatgatc actgtgatga ctactctgcc catcgtcaaa aggcttagaa
    17821 acatcaatct tatccaataa aataacatga tgatgatcgt catgtggata catcaaggcc
    17881 ttaccctctg aagtatccaa taattgaatc ttgtctaatg gcaagcctgt atttttggcg
    17941 atataagctt tttttacggc aataatatct tcagctgatt gattagtgtc tagcggtaat
    18001 ttatcagctg ctgctacagg atttgcggtt tctgatgctt ttgtaattgg tttatcagcc
    18061 atcacctcag tgctgtcaga taactgttga ttagctgtat ctgcagtatc tttatcctca
    18121 cctaacctcg gttggactac agtgtgatta tccactgctg gtgattcatc agcaaatgct
    18181 actgacgagt tagttgacat cgctaaacca gcagccatta aagcagctgg gataagtaaa
    18241 gagtatcggg taacttgatt ctttttcatt aataactcct tataactatt attcatttta
    18301 attaattaac cagttaacta tatcaatcta tcaaaaaaaa tatagtatgt caacctctta
    18361 aagtgattta atcagaacaa acgtatgaag aaaatcattt ggtgaaaaag aagcttattt
    18421 tagctgaaat agatccatta taaaagaggt gtcgtgaagt aactcaatat tcacctattt
    18481 ttgtcgcaag tattctaata ggaatagaaa aagggcagtt gcttgcaaca actacccaat
    18541 gtaaaaccgt taaagacggt gacagaaaat aactgttaac tgaactacct caaaagttaa
    18601 accaaagatc taaccgttgg atgttggttt gtagagcggt tattttttta ttgttatgtt
    18661 tacaacgact aagctcatca gtgtaaggga aagggacttc catattaaga agtatatata
    18721 catcctagat gagacgtgta atgaatgggt tgaacaaata gttgcttaat tttgggataa
    18781 gggttataat aaaaatagaa aaagggcagt tgcttgcaac aactacccaa tgcagaaccg
    18841 tttgagacgg tggctggttt tatagttaaa agataaccgt taactcgcca aagttaagga
    18901 cggttatttt ttattgtcat ctttgaagat ttgatagcac aagctgataa gcgcaatagt
    18961 aaagctacta aagcctaaaa ggatttatac cacttcaaaa gctgtcaatg ctttgactca
    19021 tcctttctgt tagattttga tgaactgccc ataggcctca cctacctttc agaaataaga
    19081 gccaccgtct taacctttct gctttatcat tatagcatat tgttattaag gttgactatt
    19141 cagactcgtc taaagaagtg taatagttgc ttaattttgg gataagggtt ataatgaaaa
    19201 tagaaaaagg tagttgctcg acacaactac ccatgcagaa ccgtttaaga cggtggcatg
    19261 ttttatgtta ttaaaaaata accgttaact cgccaaagtt aaagacggtt attttttatt
    19321 gtcatctttg aagatttgat agcacaagct gataagcgca atagtaaagc tactaaagcc
    19381 taaaaggatt tgtaccactt caaaagctgt caatgctttg gctcctcctt tctgttagat
    19441 tgtgatgaac tgcccatagg cctcacctac ctttcagaaa taagagccac cgtcttaact
    19501 tttctgcctt tttattatag cataccctat ctctgattga ctagcttaag aaggagggga
    19561 tgtgatttgg atacaaattt ttgttaactt ttttaaagtc tccaaatgat ttaaaaaaat
    19621 gatattaatg ctctaagtaa gaatattaat aatatggttt taccacttat tgtatgaggt
    19681 atcatttcta aagagttatt tttcagacag aaggcttgtt aaagcaaaca gaagcaatac
    19741 taaaggcatt agatgataat caaggccttt ttcatgtctt aaaatgagta tactagctgt
    19801 cgtgttggat agaattcata taatgattta actgcttttg attttttaaa acgattgttt
    19861 tatgaggata ttgtttaata actgctttat agttatttaa attatttttt gagcgtccgt
    19921 ctaacagaat ccatttcata aattcaacat caaatttttc attacagttt tcagccatat
    19981 caggacgtgt ttgtccccta tattttaaat atcgcttaaa agctcggtaa aaacaattaa
    20041 atctattaaa gttaaaatat ataatgtgat cagcctctct catacgctct tcataaagac
    20101 agcttgaata attaccttca ataatccaat gtttttgtga cataaatgtt gatatatcag
    20161 agaccatttg actaactgtt cgctcttgcc agtttgatgc aaaatgaatt ttgtctaaat
    20221 gaagtacagc acaattgtag tgttgaccta aaacatttgc taaagtcgac tttccagaac
    20281 cactatagcc aattattaca attttcaatc tttgtctcct ttgtcaatgc tgtactttga
    20341 cttatattat agcataaaga atatattttg gggacaaatc ctctttagac aagcaaaaaa
    20401 gcc
//
LOCUS       DARYYD010000036        19486 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.036, whole genome shotgun sequence.
ACCESSION   DARYYD010000036 DARYYD010000000
VERSION     DARYYD010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 19486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19486
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.036"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..694
                     /locus_tag="TV188_001323"
     CDS             <1..694
                     /locus_tag="TV188_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1534674.1"
                     /translation="KDNRFLDDVTRENIEELANRNEAYYKIYALGQFATLDKLIFPKY
                     EKKILNKDKLSHLPSFFGLDYGFINDPSAFLHVKIDDNNKKLYILEEYVRKNLTNDKI
                     ANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIPRIIDVKKGPGSVMQGIQYLLQYDWI
                     VDERCVKTIEELENYTWKKDKKTNEYINDPVDSYNHCIDAIRYATSNHFLTLDKKQSN
                     SFNIFRKAGFGL"
     gene            706..2208
                     /locus_tag="TV188_001324"
     CDS             706..2208
                     /locus_tag="TV188_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000930109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1534675.1"
                     /translation="MLYTETFKDSTGNAKLLEFRFHRESRMRYQTSDLSGLFDEGYKL
                     LLDYIKHHESKQKPRIQELLDYAEGNNHTVCESGRRREADMADSRAIHNYGKYISTFK
                     QGYLVGNPIRVEYEDNDDAKKQLFKELADKNNFHQLNRRLVKDLSKVGRAYELIYRSM
                     DDKTEVVRLDPRETFIIYQADVGQASLVGVRYYNKSQLDRTKKTVEVYTDNEIIYFDY
                     DGQLTEVDRRPHIFKSVPITEYLNTDDGLGDYETELSLIDLYDAAQSDTANYMQDLSD
                     AILAIIGRVSFPSYVDTKEKAIEYLRAMRKARLLNLEPPVDTEGREGSVDAKYLYKQY
                     DVNGTEAYKDRVVQDIHRFTNTPDMSDSKFAGTQSGEALKWKVFGLDQERVDLQALFE
                     QSLKRRYKLIARVSELLKEIDGFDISKLKITFTPNLPKSLHEKIEAFKALGGELSQKT
                     TMSITDIVENPDKEIASINDEAKNRSLLAQKMESEGRMTDRELARDYNHE"
     gene            2189..3766
                     /locus_tag="TV188_001325"
     CDS             2189..3766
                     /locus_tag="TV188_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL1534676.1"
                     /translation="MTTIMNKSKYWRDRVKKEMDAKEADDISLEQSMKQLHNYHFRNI
                     EKEIESFYQRYADKEKIDIAEARKRVSELDISAYQKKAKELVVKAEKLRKEGKTVTRD
                     DFTHQENADMAIYNLAMKTNALELLRLNIDLEMQELANGEHKLTKTFLDEGYRKEVEF
                     QAGLLGLSVASQASVKGLADAVINANFKGAKWSDSIWDRQDKLRSIISQSVQSAILKG
                     KNGLTIARDIRREFDVSVSYAKRIAITEHARVQMEVSRLSMAENGFAMFDIIPEPKAC
                     DVCKDIAKQGPYHMDKWRTGENTPPIHPYCRCAVVGVEEENSSNHESLDKLIKTEYNQ
                     SMKESSTYARNVLSAVSLIEPRITSQIKHIVKQSNGNLQGLDFRLKSLDSLARKISTD
                     SLLDDISPEEAANNINDALRYTAVFKPDNFFDDYHSMKNALVRDGFKIEKVKNTWLDD
                     GPYNGVNTVVSKDNVKFEIQYHTQESFDLKNGKLHELYEERRLPNITRKRKAELDKMM
                     FELSKSLTKPNQIERVN"
     gene            3768..3974
                     /locus_tag="TV188_001326"
     CDS             3768..3974
                     /locus_tag="TV188_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534677.1"
                     /translation="MITKYFFIKTEHPKIVRYSNGLTEVYNSAKGWEEQEAWYDRLFF
                     SDFSDFEEVTEKEAKMFIAGLTAA"
     gene            3971..4390
                     /locus_tag="TV188_001327"
     CDS             3971..4390
                     /locus_tag="TV188_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1534678.1"
                     /translation="MSIVELAFRVAKKAHLGQVDKAGVDYIKHPITVASFVKTDEEKA
                     TAYLHDVIEDTSLTLLDLEEYDFPRSVIEAVDILTKKKGQDYQSYLNLVKTNKLARTV
                     KLADLKHNSDLSRLSEVTNKDLKRYKKYQEAIKYLNN"
     gene            4587..4856
                     /locus_tag="TV188_001328"
     CDS             4587..4856
                     /locus_tag="TV188_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534679.1"
                     /translation="MNKRIKKKRKLETVVVMLVAENALQAEALINQNKEIMELKSIVE
                     RNALATNEELATVKDTVLDNQSVIKAIGDTVDYIKQNYKRKWGKK"
     gene            4892..5059
                     /locus_tag="TV188_001329"
     CDS             4892..5059
                     /locus_tag="TV188_001329"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534680.1"
                     /translation="MKVKEIAQVFNEYSDFFVVQNGKYLPGDRTSFFLDCELEIKEIS
                     IGIPDCLIIEV"
     gene            5241..5864
                     /locus_tag="TV188_001330"
     CDS             5241..5864
                     /locus_tag="TV188_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1534681.1"
                     /translation="MNKKLLEKLFKCAPDTGTGSGGASDADSQQSETDGEPSSEDSFK
                     APQSQSELDSYTNKAIQKALENQRKDEAKRIEEAVKAALDKEKDYSKLSEEERQQREF
                     EDSKKAFEAEKAKFEHDKLVVQVEKDLIAKGLPSEFAELLATKDAENALEQVKTFEAA
                     FKKAVADEVKKTVRQLTPSTGAGAISTQTNYGANLASKIAQQSTTLF"
     gene            5875..6255
                     /locus_tag="TV188_001331"
     CDS             5875..6255
                     /locus_tag="TV188_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HEL1534682.1"
                     /translation="MNKRKVTTSKEILHNLEYEAITVTLDSSTVGKKVIPAGTVLAGV
                     SDSVFKDRKQKVKTVANHEVSGESNICGILLTDVDLTDGDKAGACVYRGTVNADKLAD
                     SSIAENFTELATKLPHVVFIKGGK"
     gene            6258..7307
                     /locus_tag="TV188_001332"
     CDS             6258..7307
                     /locus_tag="TV188_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HEL1534683.1"
                     /translation="MALIHEIITSENIKGFYNAKNENIDKTLGEKAFPPKQQLGLKLS
                     FIKGAAGKPVTLKAAAFDTKVPLRDRMAVELLDEEMPYFKEAMLVKEADRQELNIISQ
                     TKNSDLIDTVLAAIYNDKVTLIAGAKARLEAMRMEVLSKGKIHVASNGVMKDFDYGLD
                     SSQTTKPSVKWSEAETATPLKDIEGAIEKMAERGFVPEAIIMNSKTFSLIKNAKSTLK
                     IIKPMAPDGAAVTKGDLTTYIADELGLKILFKDGMFIGDDGKSRKYFPDGFATLVPNG
                     NLGYTVFGTTPEQSDLMGGHATDADVSLVETGIAITTTKTTDPVNVQTKVSMIALPSF
                     ERLEEVQIIDSIDQV"
     gene            7318..7584
                     /locus_tag="TV188_001333"
     CDS             7318..7584
                     /locus_tag="TV188_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534684.1"
                     /translation="MAEVIKTFRDKETTNTYYVGDDYNGDRIDELTAKGYLSGDKVSA
                     AAIEIDLDKLKVDEIRAKLDELGVAHDPKLKKPELLELLKQSAS"
     gene            7594..7947
                     /locus_tag="TV188_001334"
     CDS             7594..7947
                     /locus_tag="TV188_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1534685.1"
                     /translation="MQKINTDSIIANVKLDLGIDDTLQDSLLNMLLKRVTDHFKAEYG
                     VDDIDNAFSFVLEDCLIARFNRRGSERAKSEEVEGHKTTYYDFLNEFEPYDKMIKSNL
                     NLIKDNSRKGGLYFL"
     gene            7944..8252
                     /locus_tag="TV188_001335"
     CDS             7944..8252
                     /locus_tag="TV188_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534686.1"
                     /translation="MRYADRITFVKATDEQYDPDLGEYTYTEVMIKTLPCFVMDLGMA
                     KSVQIFGDYQKTRKVVYLRQPYTDLLDHCLYKGKKYKVQVDKQFNTVFYLEGDDSICS
                     "
     gene            8233..8598
                     /locus_tag="TV188_001336"
     CDS             8233..8598
                     /locus_tag="TV188_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1534687.1"
                     /translation="MILFVADISLKVVGTTGLKNKLELIAKKEAVKKIVRDNGKQLHR
                     KMVQKAVFTKGHSTGATRISITMQIGDDGFSVTVKPGTHYAGYLEKGTRFMSKQPFVL
                     PALKEQKVKFRKDLEALVK"
     gene            8595..8984
                     /locus_tag="TV188_001337"
     CDS             8595..8984
                     /locus_tag="TV188_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1534688.1"
                     /translation="MIKTRDQSIFDEMFKRIQSLGFKVYDYKPMTEVPYPFVEMESTD
                     AEYIPNKDDIKGSVDLVLSVWGLQKKRKQVSDMASAIFSQAMSVASSDSFYWSLNIRQ
                     SSIQVLDDTTTVTPLKRAIVTLRFNLR"
     gene            8994..9585
                     /locus_tag="TV188_001338"
                     /pseudo
     CDS             8994..9585
                     /locus_tag="TV188_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052382.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
     gene            9647..10006
                     /locus_tag="TV188_001339"
     CDS             9647..10006
                     /locus_tag="TV188_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly chaperone"
                     /protein_id="HEL1534689.1"
                     /translation="MQLEIKGKTHNIKFGTRFVAEMDKNHIAEREGMKFGAGLQSTVP
                     FLFERNVVTLAEIIYTGTITESPRPSLNDIYDYIDEAEDIEKLFDDVLDELRQSNASK
                     LFITKLDKNIAEMATEA"
     gene            10048..10377
                     /locus_tag="TV188_001340"
     CDS             10048..10377
                     /locus_tag="TV188_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534690.1"
                     /translation="MIVLNCVRYLGMTDINEIGRLTLYEYDLLMIGKALASVDEAYKA
                     HKQAWINHQVSATRLVGGGKNKREVPVYKTFKEFFDYETEIKKITNEIDESYDKKAMD
                     LLLKANL"
     gene            10394..13648
                     /locus_tag="TV188_001341"
     CDS             10394..13648
                     /locus_tag="TV188_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1534691.1"
                     /translation="MGESYSVEAVLTAVDKTFGKTLKSAVQSIEGLEKRSKGFSAVSQ
                     KAGSMFKSMLGANLAGQAITALGRTVSSGLISMIGEMNSSAKAWKTFDANLADIGFGK
                     QQILEAKTAMQDYATKTIYSASDMASTYAQLAAVGVKDTGKLVKAFGGLAASAENPKQ
                     AMKSISQQMTQAVGRPTVAWQDFRIMLEQAPAGMAKVAKAMGKNLNELVADIQAGRVK
                     TKDFLEAVKQAGNDKSFQKMATEFKTVDQAIDGMREGLSNKLQPAFEKVNQFGIRAIE
                     AIGKQLDKINFSKFAAGLGKFLEGVNIDSIISRISTSISSIVSKIKGFWDGFNQTGAI
                     SAFSGALQSVWGALKNTAKAMSGGSWKTFGSIIGEIVKHVSNFARVIGDVVGKMDPSR
                     LKSWIATLAAVGGGLKIFEKLTGQSVIGSFLDKIGSKFKIFGNKAKEGTEQAFNGVKR
                     SGGIISKIFNGLGNIVKSAGTAIATAAKGIATGFSIAFKGLGSAISMVPPATWLALGA
                     AILAVGAAFALAGTQADGISQIFKTVGDVVVQVLQQVTNSLATLIPIIVSAIGSILPI
                     VAGAISQVVAAVAGGLSQIITAVANGVSTIIGAFTGLLGGVSSVITSISGVIQSLAGV
                     ITSVFNGIATIISSVGSAIKDVLTGLGSAFKGFGNGVKSALEGVGTVIKSFGSAVRNV
                     LDGVAHIFDSMGNAALNAGRGVKEMAKGIKMLVDLSLADLVATLGAVATGLGNMAGSA
                     GQMTTLSSAMSEVANGMARLGTSATIAITGLTVFATTITTIQTAIATLPTILTAAASG
                     FREIGDSATAAVGRIQTFAAGTTVVASAFASMQSMIRSAMAAIVSSIITSFNQAASQI
                     QSILSRVLSQARTFGSQLEQQMRQSGQRSGQNLAQGLSSQQGAVINAVSSMVNAAVSR
                     ANAGASPMRQAGAYIGQGLAQGMYSALGAVTAAANALVAQAERAARAKAMIHSPSRLF
                     AKRVGQYIPQGVAMGIYKNADVVDDSVGELFDSINSFDFNIADRLTSIGARFQGVVKS
                     ESSQSLSQQQEFVHTAQPAYVNFSLGGNEYEAFVSDITNRQAKIEKIRLKRSSW"
     gene            13680..14459
                     /locus_tag="TV188_001342"
     CDS             13680..14459
                     /locus_tag="TV188_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEL1534692.1"
                     /translation="MYEFNDTIRGTPKVTFNLKTTIGEKVLEEELNNDLGTFRTLTVS
                     GRDMVDLEHQTTSVLGRDGEYFHNATVEVRKLEIKAKITGKDNRSMRLQYEKLNRLIV
                     SHNQVFLSFSDEPDRNYLGIFKSKDIPEEVSNEQIIGLVFICYDPFKMSDIKTKKGNT
                     VQNDGLFNTKPIITLNLSSSTKEIRLLHVESQKYIRLTGTYTTDEIKIDMTTGKITQN
                     GRNILSDLDMVNSRYFDLLPGKNTLQCDNATITADFREVYL"
     gene            14456..16513
                     /locus_tag="TV188_001343"
     CDS             14456..16513
                     /locus_tag="TV188_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1534693.1"
                     /translation="MIYLFDKLEQLVATVGTDDLLSWHFKVKNNDWDQASFEVPVDYD
                     IEPFVYFGFFNYDPSQKEDVFKLFKVIDYNLEDSKYYKGLDKAESDLDTIAIIKDKRF
                     RQSSADACIDGALEGTGYQVGKVEGISEIRTLSYYYISPRAAMIKMIEAFNCEFNVRY
                     TFVNNKITSRYIDLKKRFGKPTGKQFEHGNNLLKVVYEESTDDIVTCLIGRGKGEEIQ
                     YDEPEAKEVEGHLPEAEKRQGYGRRIEFSDVVWSVEKGDSIDKPAGQNFVALDSAREE
                     YGLSQNGELKHRWGVFVNEEIEDKAELLKATWDQLQRLSIPIRIYKAEILDIGPETWK
                     GDSVAIIYDEVKIAFETRVDEIDIDKLNFNRSVVTLGDYSVVQNREARSRKEAVQNMI
                     NDSIENITGLGMNLQEFFQGIEEKIATGKKEMEDNWRKVNLEFDNFKKLIEQEGRNFR
                     ERLEAETKELDERNQKELDEFRETLKNLSLPEEAIKKITEAIKVDDIPSLKQSFDELK
                     NEVSKNSEKSRLNAEIIGTNGKTRYNKNLLVGEPNRTKTYDQDFVEIEANDGGFRRGE
                     TYTISFSQTCELLKKVAITLTQPHNKGLKLVLTPTKAKMEAQTFDLTKDIEVISVYPL
                     SYRAVLTGDWYKSKQMDFNAAEVQDLALEMSYRDVVDSNNASLILDWSSNPDVIFDGN
                     GGS"
     gene            16513..17220
                     /locus_tag="TV188_001344"
     CDS             16513..17220
                     /locus_tag="TV188_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1534694.1"
                     /translation="MSETISAIVVHKSMTKNEWESSDIILPQGQLVYESDTGHSKFGD
                     GKNRYADLIYQGGPPGAQGPQGPAGETGPQGPPGPTGQRGETGPQGPPGPQGPPGADG
                     KMTFEQLTPEQKQQLKGAGIQSISLDYEGYLTIQLDNGQSFRSDISLKGPQGEPGING
                     MDGPRGATGPQGPAGDPASIPDDVVRRGELAAYLLKSEYKAKGAGSGLSYKVVTQSEY
                     DDLYDYSDNELILVTEG"
     gene            17222..17836
                     /locus_tag="TV188_001345"
     CDS             17222..17836
                     /locus_tag="TV188_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534695.1"
                     /translation="MAYKLYTKADVGDNMLLVVGHLPDNTKRLKIQRETLDVLSITHY
                     SSYDMVQLKSTVKRSHSKNTVVTLVAAAASKPKAKPKHVLNFAKANKVYLGSTRVIAV
                     YLGDRLLWSDKDSSGNKTVSVVGSLDIRQSQKMLYLYLIASDIADVKSKRIKSIAING
                     VNLSSAAQINFEDSDYYCLVTIERVANIKEIKNIAQKNKITLEF"
     gene            17847..>19486
                     /locus_tag="TV188_001346"
     CDS             17847..>19486
                     /locus_tag="TV188_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1534696.1"
                     /translation="MSRDPTIVIDETNLVIGTDGRMHYTFTASQDNQKVRLKSNCLGT
                     AHFNQLMIERGDQATDYVAPVVVEGTGQATGVFKSLEEMLSGLKSIKLELTDTKNSNL
                     WSKIKLTTNGLLREYHHDHISTEIVETAAGIAKRIVDDTGQKLALINETIKGVKREYQ
                     DADRQLSASYQASIDGLKAQLANDKIGLQAEIKLSAQGLSQKYDDELRKLSAKITTTS
                     SGTTEAYENKLEGLRAEFTRSNQGMRTELESQISGLKAVQQSTAKQISQEIKDRAGAV
                     SRVQQDLDSYQRRLQDAEDNYSSLTQTVKGLQSTVSDPKGKIQSRFTQLQGQIEHRVT
                     RDGVMSIINESGDSIKLAIQKAGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNT
                     TVNGAFGAKLGEFIKLKADQIIGGSIDAAKIRVINLNASSIVGLDANFIRAKIEHTIT
                     SLLEGKVIRARNGAMMIDLLNSKIDFNSNATINFNNKDNALVRKDGTHTAFVHFSNAT
                     PKNYTGSALYASIGITSSGDGINSASSGRFCGARFFRYA"
BASE COUNT         6568 a         3422 c         4395 g         5101 t
ORIGIN      
        1 taaagacaac cgtttcttag atgatgtcac gagagaaaat atcgaggaac tagccaatag
       61 gaatgaagct tattacaaaa tatatgccct tggccagttt gcgacattag ataagcttat
      121 cttcccaaaa tacgaaaaga aaatattaaa taaagacaaa ttatcacact tgccttcttt
      181 ttttggcttg gactatggat ttattaatga tccatcggca tttttgcatg tcaaaattga
      241 tgataacaat aaaaaacttt acatcttaga ggagtatgtg agaaaaaatc taacaaatga
      301 taagatagca aatgctataa aggacctcgg atatgccaaa gaagagatta ggggagactc
      361 agcagaaaag aaatcaaatc aagagcttag aaatttaggt atcccaagga taatcgatgt
      421 taagaaaggt ccggggtctg tcatgcaagg gattcagtat ctgctgcaat atgactggat
      481 agttgatgaa agatgtgtca agaccattga agagttagaa aattatacct ggaaaaaaga
      541 taaaaaaaca aatgagtata ttaacgaccc agtcgatagt tataaccact gcattgacgc
      601 gattaggtat gcgacatcta atcatttctt gacactggac aaaaaacaat ccaatagctt
      661 taatattttc cgcaaagcag gtttcggact ctagaaagga gaacaatgtt atacacagaa
      721 acgtttaaag acagcacagg taatgctaaa ttacttgagt ttagattcca tcgtgagtct
      781 cgtatgaggt atcagacaag cgatttaagc ggcctttttg acgaagggta taaactattg
      841 cttgactata tcaaacacca cgaaagcaag caaaaaccac gcatacagga gcttttagac
      901 tatgctgagg gtaataatca tacagtctgc gaatcaggcc gcagacgaga ggctgatatg
      961 gcagacagtc gtgctataca caactacggt aagtatatct cgacctttaa gcagggctat
     1021 ttagttggaa atcctatccg cgtggaatat gaggacaatg atgatgctaa aaaacaattg
     1081 ttcaaggagc tggcggataa aaataacttc caccaactta accgtagact tgtcaaggat
     1141 ttatccaagg taggccgcgc ctatgaactt atctatcgca gcatggacga taagacagag
     1201 gttgtgcgat tagatccacg agaaaccttt attatctatc aagctgatgt tgggcaagct
     1261 agccttgtgg gtgtgaggta ctataacaag agtcagctgg atagaacaaa gaaaacagtt
     1321 gaggtctaca cagataacga gatcatttac tttgattatg atgggcaact gacagaggtt
     1381 gataggcggc cacacatttt taaatctgta cctatcacag agtatctcaa tacggacgat
     1441 ggccttggtg attatgagac ggagttgtct ttaattgact tgtatgatgc agctcaatca
     1501 gacacagcaa actatatgca agatttgtca gatgcaatct tggctattat tggtcgagta
     1561 tcgttcccga gttatgtaga caccaaggaa aaagccattg aatatctgcg tgctatgcgc
     1621 aaagctaggt tgctaaattt agagccacca gtggataccg aaggtagaga aggttctgta
     1681 gatgctaagt atctctataa gcaatatgat gtcaacggca cagaagctta taaagatagg
     1741 gttgtgcaag atatccacag atttaccaac acaccagata tgtcagatag caaatttgca
     1801 ggcacgcaat ctggagaggc actcaagtgg aaagtctttg ggcttgacca agagcgtgta
     1861 gacttgcaag cactgtttga gcaatctcta aaacgtagat ataagcttat cgcaagagtt
     1921 agtgagctgt taaaagaaat tgacggattt gacattagca aacttaaaat tacttttacc
     1981 cctaacttac caaaatcgct acatgaaaaa attgaagctt ttaaagcact tggaggggag
     2041 ttgtcgcaaa aaacaacaat gtctattaca gatattgtgg aaaatcctga taaagagatt
     2101 gcttccatca acgatgaggc taaaaatcgt agtttattgg cgcaaaagat ggagtcagaa
     2161 ggtagaatga cggataggga gttagctcgt gactacaatc atgaataaga gtaaatattg
     2221 gcgtgatcgt gttaaaaaag aaatggacgc aaaagaggca gatgatatct cccttgaaca
     2281 gtccatgaaa caattacaca attatcattt tagaaatatc gaaaaagaaa ttgagtcatt
     2341 ttatcaacgt tacgctgata aagagaaaat agacatcgca gaagcccgta agagagtttc
     2401 tgagcttgac atttctgctt accagaagaa agctaaggaa cttgttgtaa aggctgagaa
     2461 gctacgaaaa gagggtaaga cagtaacgag agatgacttt acccaccaag aaaatgcaga
     2521 catggccatc tacaatttag cgatgaaaac taacgcttta gaattgttgc gcttgaatat
     2581 cgacttggag atgcaggagc tcgcaaatgg cgaacataag ctaaccaaga catttcttga
     2641 cgaaggatac cgcaaagagg ttgagttcca agcgggattg ttaggactgt cggttgctag
     2701 ccaagcaagc gtgaaagggt tggctgacgc agttattaac gctaatttca aaggcgcaaa
     2761 atggtcggat agcatttggg acagacaaga taaattacgc agcattatat cccagagcgt
     2821 acagagtgct atcttaaaag gtaaaaatgg tttaactatt gcaagggata ttagacgaga
     2881 gtttgatgtg tcagtgtctt atgcaaagcg aatagcaatc actgagcatg caagggtgca
     2941 gatggaagtt agtagattat ccatggcgga gaatggcttt gctatgtttg acattatccc
     3001 agagcctaaa gcatgtgatg tttgtaaaga cattgctaaa caaggtccat atcacatgga
     3061 taagtggcga acaggggaaa acacgccgcc catccatcct tattgcaggt gtgcagttgt
     3121 tggagtggaa gaagaaaata gtagtaatca tgaatcactt gataagctta ttaaaacaga
     3181 gtataatcaa agtatgaaag agtcatcgac ttatgctcgt aacgttttgt cggcagtgtc
     3241 attgatagag cctcgaatta catcgcaaat taagcatatt gtcaagcaat ccaacggtaa
     3301 tttacaagga cttgatttta gattaaaaag tctagattct ttggccagaa agatctctac
     3361 tgatagcttg ttggacgata tttcaccgga agaagccgca aacaacataa atgatgcatt
     3421 acgctataca gctgtattta aaccagataa tttttttgat gattatcata gcatgaaaaa
     3481 tgcattggtc agagatggtt ttaaaatcga aaaggtgaaa aatacttggc tagatgatgg
     3541 tccatataac ggtgttaata ctgttgtatc aaaagacaat gtcaagtttg aaattcaata
     3601 tcatacccaa gaaagctttg atttaaaaaa cgggaaactg catgaattat atgaggagag
     3661 aagacttcct aatataacac gaaaacggaa ggctgaacta gacaaaatga tgtttgagct
     3721 tagtaaatct ttaactaaac ctaaccaaat agaaagggtg aattgatatg attacaaaat
     3781 atttttttat aaaaaccgaa caccccaaaa ttgttagata ttctaatggg ttaacagaag
     3841 tttataacag cgcaaaaggc tgggaagaac aagaagcttg gtacgatcgt ctattcttta
     3901 gcgatttcag tgattttgaa gaggttacag aaaaagaagc taaaatgttt attgcgggat
     3961 tgacagcggc atgagtattg tggagctagc tttcagagtg gctaaaaaag cccaccttgg
     4021 acaggttgat aaggccggtg tcgactatat taagcaccct ataactgttg caagttttgt
     4081 aaaaactgat gaagaaaagg caacggctta tcttcatgat gttatcgaag atacaagttt
     4141 gactttactt gacttggaag agtatgattt tcctcgaagt gttatagagg cagttgatat
     4201 actgacaaag aaaaaaggac aggattatca atcctatcta aaccttgtta aaacaaataa
     4261 acttgcaaga actgtaaaat tagctgattt aaaacacaat tctgatttat ctcgtctctc
     4321 tgaagtaact aacaaagatt taaaacgcta taaaaaatat caagaagcta tcaaatattt
     4381 aaacaattaa acaacaacag acgggcaacc gtcttttttt gtaccccaaa aacaggagga
     4441 aatgatgttg aaaatagtga aatttttgaa atatgtttgg atttataagt gtaaacctgt
     4501 cagtccaagt ctttatgcat cgagtcggat tgagtacttc aaacctcttg gttattactg
     4561 ggaaaaagca acgataggag aaagcaatga ataaacgaat caaaaagaaa cgtaaactag
     4621 aaacagtagt agtgatgctg gttgcggaaa atgccttgca ggctgaagcg ctcataaatc
     4681 aaaacaaaga aatcatggag ctaaaatcaa tcgttgagcg aaacgctctg gcaacaaacg
     4741 aagagttagc gactgttaaa gacaccgttt tagacaacca atcagttatc aaggcaattg
     4801 gtgacacggt tgactacatc aagcaaaatt acaaacgtaa gtgggggaag aaatgaagta
     4861 tctcaagaaa aagtaatagt aaggagttat tttgaaagtc aaagagatag cacaggtgtt
     4921 taatgaatat tcggattttt ttgtggtaca aaacggtaaa tatctacctg gtgacagaac
     4981 tagttttttt ctagattgcg aattggaaat caaagaaata tctatcggaa ttcctgattg
     5041 cttaattatt gaagtataaa aaattcaaag tcgtagcaat acggcttttt attgtgccct
     5101 gagcatggcc taaaaaggct caaattaatc actagcgtgg cttgtggata aatacaccta
     5161 atagagacta gaaaacatga ggcgcccgtt ttcgtggctc tgcagtgtgt ttaaaagcaa
     5221 gactagcgtg ggaggaaaaa atgaataaaa aactattaga aaaacttttt aaatgtgctc
     5281 cagatactgg cacaggttca ggaggagctt ctgatgcaga tagccaacaa tccgaaacag
     5341 atggagaacc atctagtgaa gacagcttta aagctccaca gtcgcaatca gagttagata
     5401 gctatacgaa taaagcaatc caaaaggcat tggaaaatca acgcaaagat gaagctaaac
     5461 gaatagaaga agctgtaaaa gctgctttag ataaagaaaa agactactcc aagctatctg
     5521 aagaagaacg tcagcagcgt gaatttgaag atagtaagaa agcctttgaa gctgaaaaag
     5581 ccaagtttga acacgataaa cttgtagtcc aagtcgaaaa ggatcttatc gcaaagggat
     5641 tgccttctga gtttgctgaa ttgcttgcta caaaagatgc agaaaatgcg ctagagcaag
     5701 tcaaaacatt cgaagcagca tttaaaaaag cagtagctga tgaagttaaa aagaccgtac
     5761 gacaacttac tccatcaact ggggcaggtg caatatcaac acaaacaaac tatggggcga
     5821 acttggcgag taagatcgca caacaaagca ccacattatt ttaggaggaa aaaaatgaat
     5881 aaacgtaaag taacaacatc aaaagagatt ctccacaatc tcgaatacga agctattaca
     5941 gtcactttag attcaagcac agttggcaaa aaagttattc cagccggtac agttttggcc
     6001 ggtgtatcgg attctgtttt taaagatcgc aaacaaaaag taaaaactgt ggcaaatcac
     6061 gaggtcagcg gagagagcaa tatttgtgga attttgttaa ccgatgttga tttgacagat
     6121 ggtgataaag caggtgcttg tgtttatcgc ggtactgtca acgcagataa acttgctgat
     6181 tcatcaattg cagaaaattt tacggaattg gcgacaaaac taccacatgt tgtctttatt
     6241 aagggaggta agtaagcatg gcattgatcc acgaaattat cacatcggaa aacatcaaag
     6301 gtttttataa tgctaaaaat gagaacattg ataaaacgtt aggggaaaaa gcattcccac
     6361 caaaacagca attagggctt aagctatcct ttatcaaggg tgcggcagga aaacctgtga
     6421 cacttaaagc ggccgctttt gatactaaag tacctctacg tgaccgcatg gcagttgagc
     6481 tgcttgacga agaaatgcct tactttaaag aggctatgct tgttaaagag gcagaccgtc
     6541 aagagcttaa cattatatct caaacaaaaa atagtgatct tattgacaca gttttagcgg
     6601 caatttataa cgataaggta acgcttatcg caggcgctaa agcacgttta gaagcaatgc
     6661 gtatggaagt gctgtctaaa ggtaaaatcc acgtcgcatc aaacggtgtc atgaaagact
     6721 ttgattatgg actagactct tcgcaaacaa ctaagccaag tgttaaatgg tctgaggcag
     6781 agaccgcgac accacttaaa gacattgaag gtgcaattga aaaaatggca gaacgtggct
     6841 ttgtgccaga agcaattatc atgaactcta agacatttag tttgattaaa aacgctaaat
     6901 caactcttaa aatcatcaaa ccaatggcac cagatggggc agctgttacc aaaggtgatt
     6961 tgacgactta tattgctgat gaactaggac tcaaaatttt gtttaaagat ggtatgttca
     7021 ttggtgacga tggcaaatct cgtaagtatt tcccagatgg ctttgcaact ttggtaccta
     7081 acggcaacct tggctacact gtgtttggca ctactccaga gcaatcagat ctcatgggtg
     7141 ggcacgcaac agatgcagat gtgtcgttgg ttgagactgg tattgcaatc acaactacta
     7201 agacaactga tccagtaaat gttcaaacca aggtatctat gattgctttg ccgtcattcg
     7261 aacgattgga agaagtgcaa attatcgact ccattgacca agtataagga gggggttatg
     7321 gctgaagtta ttaaaacttt tagggataaa gaaaccacta acacttacta cgtaggagac
     7381 gattacaacg gagaccgcat tgatgagttg acagctaaag gatacctatc tggtgataag
     7441 gtttctgctg ccgctataga gattgacctt gacaaattaa aggttgacga aattagagca
     7501 aaacttgatg agttaggcgt cgctcatgac cctaaactaa aaaagccaga attattagaa
     7561 cttttgaaac agtcagctag ctaggaggtg tttatgcaaa agataaacac agatagcatt
     7621 atagctaacg taaaactcga tttaggtatt gatgacacct tgcaagacag tttgctcaat
     7681 atgttgctaa aacgtgttac agaccatttt aaagcggaat acggcgttga tgatatagac
     7741 aacgcctttt cgtttgtttt ggaagactgt ctaattgcta ggtttaatcg cagagggtca
     7801 gagagggcta agtcggaaga ggtagagggt cataaaacaa cctactatga ctttttaaat
     7861 gagtttgagc cttacgacaa aatgattaag tccaacctta atttgattaa ggataattct
     7921 cgtaaagggg gattgtactt tttatgagat atgcagatag gattacgttt gttaaggcga
     7981 cagatgaaca atatgaccct gatttaggtg agtacacata taccgaagtc atgatcaaga
     8041 cattgccttg ttttgtcatg gacttaggta tggctaaatc tgtgcagatt ttcggagact
     8101 atcaaaaaac acgaaaagtt gtttatttgc gccaacctta taccgatttg ttagatcact
     8161 gtctctacaa aggcaaaaag tacaaggtac aggtggataa gcaatttaat actgtttttt
     8221 atctggaggg agatgattct atttgtagct gatatatctt taaaagtagt tggaacgaca
     8281 gggctaaaga ataaacttga acttattgcc aaaaaagagg ctgtcaagaa gattgttaga
     8341 gataatggaa aacaactaca caggaaaatg gtccaaaagg cagtatttac caaaggtcat
     8401 tccactggtg ctaccagaat atccatcaca atgcagattg gtgatgatgg ttttagtgtt
     8461 acagtaaaac ctggcacgca ttatgcaggt tatttagaaa aaggcactcg ctttatgagt
     8521 aagcaacctt ttgtgttgcc agctctaaaa gagcaaaaag taaaattcag aaaagatttg
     8581 gaggcgcttg tcaaatgatt aaaactagag atcaatctat ttttgacgag atgtttaagc
     8641 gtattcagtc tttaggtttt aaagtttatg attacaaacc gatgactgag gttccttatc
     8701 cgtttgtgga aatggaatct actgatgcag aatatattcc aaataaagat gacattaaag
     8761 gctctgttga cctcgtactg tctgtttggg gattgcaaaa aaaacgaaag caggtgtctg
     8821 atatggcatc tgctattttt tcacaagcta tgtcagtggc tagttctgac agcttttact
     8881 ggtcgttaaa tattcgtcaa tcatctatcc aagtgttaga tgacacaaca acagtgacac
     8941 ctctcaagag agcgattgtc acattaagat ttaatttaag ataggaggtc gcaatgccag
     9001 gaccaagtag attaggatcc aaagatgaag accactccac acaagaaagg aaggaaaaaa
     9061 tggcagcgca agatcaagta caattagaag caaaacaagg gattcatgca atcctattat
     9121 tccgtttgtt aaaagaagca tcatcagaaa aagcagctaa actcgctttt caaacggaac
     9181 acgaagttgg taaaagtcgt gatgtcgacg gtcaaaagac taaagatggt attatccagt
     9241 ctgtcggagc tttagaatac gactttaaag caacatctat tttagccaaa ggtgacaagt
     9301 tagcagcaaa actagaagaa gccatggaaa aaggtgagct tgttgaaatt tgggatattg
     9361 attccgaaaa agcaagtgaa gaagcttgat agcaaaggta aatatccagc tacctattac
     9421 caaggttaca tttcaagttt cggcgctaag aaaaatgcag aagaaaatat tgaaattgaa
     9481 atggaatttg ccattaatgg cgttggtcaa aaaggatttg caacattgac cgaagaacaa
     9541 aaagcagctg tacagtacaa atttaaagat acaacagcag gttaatcaac aaggccagtt
     9601 aattactggt cttttatttt taaattttta aagggggaaa agaataatgc aattggaaat
     9661 taaaggtaaa actcataaca tcaaatttgg cacacgattt gttgctgaaa tggataagaa
     9721 tcacattgca gaacgtgaag ggatgaagtt tggcgctggt ttgcaatcaa ctgttccgtt
     9781 tttgtttgag cgtaacgttg tgacacttgc tgagattatc tatacaggga caatcacaga
     9841 gtcaccacga ccaagcttaa atgatattta cgactacatc gatgaggctg aagatattga
     9901 gaagcttttc gatgatgttt tagatgagtt gcgccaatct aacgcgtcaa agttgtttat
     9961 caccaaactg gacaaaaaca tagcggagat ggcaaccgaa gcttaaagag ttcaaccaaa
    10021 aattattctt cacaagaaag ctttgagatg attgtcctta attgtgttag atatcttggc
    10081 atgactgaca ttaatgagat tggtcggttg actttgtatg aatatgattt attgatgata
    10141 ggtaaagcgc tagcctctgt agacgaggca tataaagctc acaagcaagc ttggataaat
    10201 caccaggtct cagctacgag gctggtcggt ggtggtaaaa acaaaagaga agttcctgtt
    10261 tataaaacat tcaaggaatt ttttgattat gaaacagaaa tcaagaagat aaccaatgaa
    10321 attgatgaaa gctatgacaa gaaagcaatg gatttacttt taaaagccaa cctttaaata
    10381 gaaaggaagt taaatgggag aatcttattc agttgaagcg gtgttgacag cggttgataa
    10441 aacctttggt aagactttaa aatcagcagt tcaatcaatt gaaggactag aaaagcgttc
    10501 aaaaggcttc tcggcggtgt ctcaaaaggc tgggtctatg tttaaaagca tgcttggagc
    10561 taacttagca ggtcaagcta ttacagcgct aggacgtaca gtttcatctg gacttatttc
    10621 gatgatcggc gaaatgaata gctcagcaaa agcgtggaaa actttcgatg ccaatttagc
    10681 agatatcgga tttggcaaac agcaaattct tgaagctaaa acagctatgc aagattacgc
    10741 tactaaaaca atctactcag catcagatat ggccagcaca tatgcacagt tagctgctgt
    10801 tggggtaaag gatactggga aactcgtaaa agcttttggt ggtttggctg catctgctga
    10861 aaatccaaaa caagctatga agtcaatcag tcagcagatg acacaagctg tgggaagacc
    10921 tacagtagcg tggcaagatt tcagaataat gctcgagcaa gctccagctg gtatggctaa
    10981 agtggccaaa gctatgggca aaaaccttaa tgaacttgta gccgacattc aggctggtag
    11041 agtaaaaact aaagacttcc tagaagcagt aaaacaagct ggtaacgaca aaagcttcca
    11101 gaagatggcg actgaattca aaactgtgga ccaagccatt gatggcatgc gtgaaggttt
    11161 atccaataaa ttgcaaccag cttttgaaaa agtgaaccaa tttggaatta gagcgattga
    11221 agcaatcggg aaacaactcg ataaaatcaa tttttccaaa tttgctgcag gccttggtaa
    11281 atttctcgag ggcgtgaaca ttgatagtat tatttcaaga atatcaacat caatttcatc
    11341 tatcgtttct aaaataaaag gattctggga cggatttaat caaactggag caatcagcgc
    11401 tttttccggt gctttacaaa gtgtttgggg agcgttaaaa aatactgcta aagccatgag
    11461 tggaggaagc tggaagacct tcgggtcaat cattggcgaa attgttaaac atgtttctaa
    11521 tttcgcaaga gtgattggag atgtcgttgg caagatggat ccgagtagac taaaaagctg
    11581 gatagctact cttgcagctg ttggtggtgg attgaaaatc tttgagaaat taacaggtca
    11641 aagtgttatt ggatcttttt tagacaaaat cggctcaaaa ttcaaaatat ttggaaataa
    11701 agccaaagaa gggacagaac aagcctttaa cggagtcaaa agaagtggtg gcattatcag
    11761 taaaatcttt aacggtttgg gtaatatcgt taagtctgcc ggtacagcga tagcgactgc
    11821 tgcaaaaggt atcgcaactg gtttttctat cgcgtttaag gggcttgggt ctgccatttc
    11881 tatggtaccg ccagctacat ggctagcttt aggagcagct attttagcgg taggagcggc
    11941 ttttgccttg gcaggaactc aagctgatgg cattagtcaa atttttaaaa ctgttggcga
    12001 tgtcgttgta caagttttac aacaggtcac taacagtcta gctactctaa ttcctattat
    12061 tgtaagcgct attggctcca tattaccaat tgtagcaggg gctatttctc aagtcgtcgc
    12121 agcagttgct ggcggattat ctcagattat tacagctgtt gctaatggtg tatcaactat
    12181 tattggggct ttcacaggtc tacttggtgg tgtttctagc gtcattacct caattagtgg
    12241 tgttatccaa tcgctggcag gtgtaattac ctcagtattt aatggcatag caaccattat
    12301 ttcgtctgta gggtctgcaa ttaaagatgt attaacgggt ctcggcagtg cttttaaagg
    12361 attcggcaac ggtgtaaaat cagccttaga aggcgttggg acagtaatca aatcatttgg
    12421 tagtgcagtc agaaatgtcc ttgatggtgt tgcgcatatt ttcgattcta tgggtaatgc
    12481 agctcttaat gctggtcgtg gcgtcaaaga aatggctaaa ggcatcaaga tgcttgtaga
    12541 tttatcgctt gctgatttag tcgcaacgct tggagcagtc gcgacaggtc ttgggaatat
    12601 ggctggctct gccggtcaga tgactacgtt aagttctgcc atgagcgaag tagccaatgg
    12661 tatggcgcgt ctaggaacaa gcgctacgat agcaattact ggattaacag tttttgctac
    12721 tactataaca actattcaga ccgcaattgc aactctacca acaatcctaa ctgcagccgc
    12781 tagtggtttt agggagatcg gggattcggc aactgcagca gttggtcgaa tccagacttt
    12841 tgcagctggt acaactgttg ttgcatcagc gtttgctagt atgcaatcta tgattcgatc
    12901 tgccatggct gcaatagtaa gcagcattat aacatcattt aaccaagctg cctctcaaat
    12961 acaatcaatt ttatctcggg tgctatctca agctaggaca tttggatctc aactagagca
    13021 acaaatgagg caatcgggac agcgttcagg acaaaatctt gctcaggggt tgtcttctca
    13081 acaaggtgct gttattaatg ctgtttctag catggttaat gccgcggtat caagagcaaa
    13141 tgcaggtgct agtcctatgc gtcaagctgg agcgtacatc ggacaagggc ttgcgcaagg
    13201 tatgtattca gcgctaggag ctgtaacagc agcagcaaac gctcttgtag cacaagctga
    13261 gagggcagca agagctaagg cgatgattca ctcgccatct aggttatttg caaaacgagt
    13321 tggtcaatat atccctcaag gggtagccat ggggatatat aaaaacgctg atgtcgttga
    13381 tgattctgta ggtgagctat ttgatagtat caatagcttt gattttaata ttgcggatag
    13441 attgacaagt attggcgcta gattccaagg tgttgtcaaa tcagaaagtt cgcaatcgtt
    13501 gtcgcagcaa caagagtttg tacatacagc tcaaccagcg tatgtaaact ttagtttagg
    13561 cggaaacgaa tacgaagcat ttgtaagtga catcactaat cgacaagcaa aaattgaaaa
    13621 aatcagacta aagagaagca gctggtagtt gtttctctta gttttatgaa aggagtaaaa
    13681 tgtacgaatt taacgatact atcagaggga ctccgaaagt tactttcaat ttaaaaacaa
    13741 caattggcga aaaggtatta gaagaagagc tcaataatga tttaggtacc tttaggacat
    13801 tgaccgtttc tggtcgtgat atggtggact tagaacacca gacaacaagt gttttagggc
    13861 gagatggcga gtatttccac aatgccacag ttgaagtcag aaaactagaa ataaaagcta
    13921 aaattactgg aaaagataac cggtcaatgc gtttgcaata tgaaaaatta aacagattaa
    13981 ttgttagtca taatcaagtt tttttatcat tttcagacga gccggacaga aattatctag
    14041 gcatctttaa atctaaagat ataccagaag aagtttctaa cgaacaaatc attggcttgg
    14101 ttttcatctg ttatgatcca tttaaaatgt cagatataaa aaccaaaaaa ggtaatactg
    14161 ttcaaaatga tggcctattt aatacaaaac ctatcataac tctcaacctc tcatcatcaa
    14221 caaaagaaat taggctgcta cacgtcgaaa gtcaaaagta tatcagatta actggtactt
    14281 atactactga cgaaatcaag attgatatga caacaggtaa gattacccag aacggccgta
    14341 atattcttag tgatttagac atggttaaca gtcgctattt tgatctatta cctggtaaaa
    14401 acactttgca gtgtgataat gcaacgatta cagctgattt cagggaggtt tatctatgat
    14461 ttatctcttt gataagctgg agcaattagt tgctactgtt ggtactgatg acttgctctc
    14521 atggcatttt aaggtcaaaa ataatgattg ggatcaagct agttttgagg tacctgttga
    14581 ttatgacatt gagccttttg tttactttgg tttttttaac tatgatccaa gccaaaaaga
    14641 ggacgttttt aaactcttta aagtcattga ttacaaccta gaagatagca agtattataa
    14701 aggcttagat aaggctgaga gtgaccttga tactattgct attatcaaag acaagcgctt
    14761 tagacaatcg tccgcagatg cttgtattga tggagcttta gagggcactg gttatcaagt
    14821 tggtaaagtt gagggcattt ccgagatcag gacccttagc tattattaca tcagcccacg
    14881 agctgccatg atcaagatga tagaagcttt taactgcgaa tttaatgtca gatacacctt
    14941 tgttaataac aaaattacta gtcgctatat cgaccttaaa aagcgatttg gcaagccaac
    15001 aggaaagcag tttgagcatg ggaataactt attaaaagtc gtctatgagg aatcaacaga
    15061 tgacatcgtg acttgtctga ttggccgagg caagggcgag gaaatccaat atgatgaacc
    15121 agaggcaaag gaagttgaag gacacttacc agaggcagaa aagcgtcaag gttatggccg
    15181 aagaattgaa tttagcgatg ttgtctggtc agtcgaaaaa ggcgactcga tagacaaacc
    15241 agctggtcaa aactttgtgg cgctagatag tgccagagaa gaatacggat tgtctcaaaa
    15301 tggcgagcta aaacaccgat ggggggtctt tgtcaacgag gaaattgagg acaaggcgga
    15361 actcttaaaa gccacatggg atcaattgca gcgcttatca atacccatca gaatttacaa
    15421 ggcggaaatc ttagatattg gccccgaaac gtggaaaggt gactcagtag ccattatcta
    15481 cgatgaggta aaaatagctt ttgaaactcg tgttgatgag attgatattg ataagctaaa
    15541 ctttaacagg tcggtagtaa ctctcggtga ttatagcgtt gtccaaaacc gcgaagcaag
    15601 gtcacgcaag gaagctgtcc aaaacatgat caatgatagc atagaaaaca tcaccggcct
    15661 tggcatgaac ttacaagaat tttttcaagg tattgaggaa aaaattgcca ctggcaaaaa
    15721 agagatggaa gacaattggc gtaaggttaa ccttgaattt gataacttta aaaaattaat
    15781 cgaacaagag ggacgtaact ttagagagcg tttagaagct gaaacaaagg aactagatga
    15841 acgcaaccaa aaagaactcg atgaatttcg cgaaaccctc aaaaatctgt cgctgcccga
    15901 ggaagccatt aaaaaaataa ccgaggccat caaagttgat gatatcccat cgctaaaaca
    15961 aagttttgac gagctcaaaa acgaagtcag caagaacagc gaaaaatctc gcttaaatgc
    16021 tgaaatcatc ggcacgaacg gtaagacccg ctataacaaa aatctcttgg ttggtgaacc
    16081 taatcgcacc aagacctatg atcaggattt tgtggagata gaagcaaatg acggtggttt
    16141 tagacgcggt gagacataca cgattagctt tagtcagaca tgtgagttgc taaaaaaagt
    16201 ggctatcacg ctgacgcagc cgcataacaa aggtctcaag ctggtgctga caccaaccaa
    16261 ggctaagatg gaggcgcaga cttttgacct aaccaaggac atagaggtta tcagcgtcta
    16321 tcctttgagc tacagagctg ttttaacagg tgactggtat aaatctaagc agatggattt
    16381 taatgcggca gaagtgcagg atttagctct ggagatgtct tatagagacg ttgtcgatag
    16441 caataatgct agtttgattt tggattggtc ctcaaatcca gatgttattt ttgatggaaa
    16501 tggaggtagt taatgtcaga gactatatca gctatagttg tgcataaaag catgacaaaa
    16561 aacgagtggg agtctagtga catcattttg ccacaaggcc agcttgtcta tgagtctgac
    16621 acaggccata gtaaatttgg cgacggtaaa aatagatatg cagatttgat ctatcaaggt
    16681 ggaccacctg gggcacaagg tccccaaggg ccagctggcg aaaccggtcc acaaggccca
    16741 ccaggcccta ctggtcaacg tggggaaaca ggcccacagg gtccacctgg gccacaaggg
    16801 ccgccaggag cggacggtaa aatgacgttt gagcagctca caccagagca aaaacagcag
    16861 cttaaaggtg ctggcataca aagcatatca ttggattatg agggctattt gacaatacag
    16921 ctagataatg gccaatcgtt tagatcagat attagcttaa aaggtcctca aggagagccg
    16981 gggatcaatg gtatggacgg tccaagaggc gcaacgggtc cccaaggacc agctggtgat
    17041 ccggcgagca tacctgacga tgttgtcaga cgtggtgagt tagctgcata tttgcttaaa
    17101 tcagagtata aagccaaagg cgcaggctct gggctaagct acaaagttgt cactcaatca
    17161 gagtatgatg atctgtatga ttacagcgac aatgagttga tactcgtgac ggagggttga
    17221 catggcatat aagctttaca ctaaagctga tgttggtgac aacatgttgc ttgttgttgg
    17281 ccatttgcct gacaatacaa agcgattaaa aatccagcgt gagacgttag atgtattgag
    17341 tattacccac tatagctctt atgatatggt acaactcaag tcgacagtca aaagatccca
    17401 cagcaaaaat acagttgtta ctcttgtagc tgcagctgct agcaagccca aagctaagcc
    17461 aaagcacgtt ttaaactttg ctaaggctaa taaggtctat ctaggcagca ctcgtgtaat
    17521 agcggtttat ctgggtgatc gactgctctg gtccgacaaa gacagcagcg ggaacaaaac
    17581 tgtctctgtt gtggggagtc ttgatatcag acaatcacaa aaaatgctgt atttgtactt
    17641 aatagcgtca gacattgcag atgtcaaaag caagcgcatt aaatcgatag cgataaatgg
    17701 cgttaacctg tcaagcgctg cacaaatcaa ttttgaggat agcgactatt attgtctagt
    17761 gacaatcgag cgagttgcta acatcaaaga gatcaaaaat atagcgcaaa aaaacaaaat
    17821 cacgctagag ttttaggagg taacaattga gcagagaccc aacaattgta atagacgaga
    17881 caaacctcgt tattggcaca gatggccgca tgcattacac gtttactgct agtcaagaca
    17941 accaaaaggt caggctaaaa agcaactgtt taggcacagc gcattttaac cagctgatga
    18001 ttgagcgagg agaccaagcg acggactacg ttgcgcccgt tgttgttgag ggtacaggac
    18061 aggcaacagg cgtctttaaa agtctcgagg agatgcttag tggcctaaag tcaattaaac
    18121 tggagctaac agataccaaa aactcaaatc tgtggtcaaa aatcaaattg acgacaaatg
    18181 ggcttttgcg tgagtatcat catgatcata tctcgaccga gattgtcgag acagcagctg
    18241 gtattgccaa acggattgtc gatgatactg gccaaaagct ggcactaatc aatgagacta
    18301 tcaaaggtgt taagcgtgag tatcaagacg cagatagaca gctatccgcg agctatcaag
    18361 caagtatcga tggcctcaaa gcccagctgg ccaacgacaa aattggccta caagctgaga
    18421 ttaagctgtc cgcccaaggc ttgtcgcaaa aatacgacga tgagctgcgc aagctatctg
    18481 ccaagattac aacgacatct agtggtacta cggaagccta cgaaaacaaa ctcgagggct
    18541 tacgggctga gtttactcgt agcaaccaag gcatgcggac agagcttgag tcgcaaatca
    18601 gcggcctaaa agcagtacag caatcaactg caaaacaaat ctcacaagag atcaaggata
    18661 gggcaggggc tgttagtcgt gtgcaacagg atctagatag ttaccaaaga cgcttgcaag
    18721 acgcagagga taattacagt agcttaaccc agaccgttaa aggcctgcag tcaactgtta
    18781 gcgatcccaa aggcaaaatc cagtcacgat ttacacagct gcaaggtcaa attgagcatc
    18841 gtgtgactag agatggggtt atgagtatca tcaacgagtc aggcgatagc attaagctag
    18901 cgatccaaaa ggctggtggg attgatgcta agatgagcgc taaagagatt atctcagcga
    18961 ttaatcttaa tggttatggc gtcagaatct ccggtgagcg tattgcgctg gacggtaata
    19021 cgaccgttaa cggggctttt ggagctaaac ttggtgagtt tatcaagctc aaagccgatc
    19081 aaattattgg tggttcgatt gacgctgcta agattagagt gatcaatctt aacgctagca
    19141 gcattgtcgg cttagatgct aactttatca gggctaaaat cgaacatacg attacaagtt
    19201 tgcttgaggg taaagttatc agagctcgca acggagcgat gatgattgac ttgttaaact
    19261 ctaaaattga ctttaacagc aacgctacca ttaactttaa taacaaggac aatgcgcttg
    19321 tacgtaaaga cggtacccac acagcctttg tgcattttag caatgccacg ccaaaaaatt
    19381 atacaggtag tgcgctttac gcctcgatcg ggataacctc gtcaggtgac gggattaaca
    19441 gcgcgtcgag cggtcgtttt tgcggtgcta ggttttttag gtacgc
//
LOCUS       DARYYD010000037        18217 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.037, whole genome shotgun sequence.
ACCESSION   DARYYD010000037 DARYYD010000000
VERSION     DARYYD010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18217
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.037"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            62..298
                     /locus_tag="TV188_001347"
     CDS             62..298
                     /locus_tag="TV188_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEL1534697.1"
                     /translation="MEVIRTLLMFFSHLLFIGISYQLLISLVDWSKFIHYRPENMGRL
                     RLLVLFLAIASGYLVSRFMLELIQISQYLLYDFH"
     gene            362..1633
                     /gene="murA"
                     /locus_tag="TV188_001348"
     CDS             362..1633
                     /gene="murA"
                     /locus_tag="TV188_001348"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEL1534698.1"
                     /translation="MDKIIIEGGSTRLEGEVTIEGAKNAVLPLLAATILPSTGKTVLR
                     NVPILSDVFTMNYVVRGLNIDVDFDEAANQITVDASGDILDVAPYEYVSQMRASIVVL
                     GPILARNGHAKVSMPGGCTIGSRPIDLHLKGLEAMGAEITQQGGDITAKAERLKGAMI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAQLLNKMGAKVRGAGTETLT
                     ITGVTSLCGVEHDVVQDRIEAGTFMIAAAMTSGNVLIRDAVWEHNRPLISKLMEMGVS
                     VVEEDAGIRVQADVTKLRPVTVKTLPHPGFPTDMQAQFTALMAIVKGESTMVETVFEN
                     RFQHLEEMRRMGLQSEVLRDTAMIHGGHELQGAPVMSTDLRASAALILTGMVAKGRTT
                     VNKLNHLDRGYYQFHEKLAKLGANIQRISEE"
     gene            1637..1825
                     /locus_tag="TV188_001349"
     CDS             1637..1825
                     /locus_tag="TV188_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003057490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1534699.1"
                     /translation="MTNGWRYVINQLMLIIAIGLLGLFCLALGLMIGYSLIGDGQNPL
                     AILSPDKWAELIHKFTGK"
     gene            1857..2735
                     /locus_tag="TV188_001350"
     CDS             1857..2735
                     /locus_tag="TV188_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1534700.1"
                     /translation="MIKKKKDIRLLNAFLALLLVLGTGYLAGHDDLAADNPIKQVYQR
                     ILGSDTQQAGLPKASRDWDTPSKALADSVMTATIKQQLGDVITWNGTGAYIINHNKTT
                     LNAKVASLPYANNKTKMVQGQSVPTVANALLTKSTRQYQKRNDTGNGYSSWKPAGWHQ
                     VQGLKGRYSHAVDRGHLLGYALVGGLKGFDASMANPSNIATQTAWANQAANERSTGQN
                     YYETKIRKALDSNKRVRYRVTLLYEGNNLLASGSHLEAKSSDGSLEFNVFIPNVQAGL
                     QIDYQTGQITVASSQP"
     gene            2749..2907
                     /locus_tag="TV188_001351"
     CDS             2749..2907
                     /locus_tag="TV188_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534701.1"
                     /translation="MAKADHVASHHGREALVLVVPQRKVLTIFGLVALVEKQIGPLVE
                     APSMPAPD"
     gene            3647..4690
                     /gene="pheS"
                     /locus_tag="TV188_001352"
     CDS             3647..4690
                     /gene="pheS"
                     /locus_tag="TV188_001352"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEL1534702.1"
                     /translation="MDLQAQLEELKTKTQEALKQLNGDHSKELQELRVAVLGKKGTLT
                     ELLKGLKDLSNDLRPVVGKQVNELRDFLTQAFEEQAKVVEAAKIQAKLDSESIDVTLP
                     GRQMKQGYRHVLTQISEEIEDIFLGMGFQIVDGFEVEKDYYNFERMNLPKDHPARDMQ
                     DTFYITEDILLRTHTSPVQARTLDQHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQI
                     EGLVVGKSISMGDLKGTLEMIIKKMFGKERKIRLRPSYFPFTEPSVEVDVSCFKCGGK
                     GCNVCKKTGWIEILGAGMVHPSVLEMSGVNAQEYSGFAFGLGQERIAMLRYGINDIRG
                     FYQGDSRFSKQFK"
     gene            4880..7285
                     /locus_tag="TV188_001353"
     CDS             4880..7285
                     /locus_tag="TV188_001353"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEL1534703.1"
                     /translation="MLVSYKWLKKLVDIDVSPAELAEKMSTTGIEVEGITSPSEGLSK
                     LVVGHIVSCDAVPETHLHLCQVNTGDDELRQIVCGAPNVKAGINVIVALPGARIADNY
                     KIKKGKIRGMESLGMICSLQELGLPDAIIPKDFSEGIQILPETAAAGDSIFPYLDLDD
                     NIIELSITPNRADALSMRGVAHEVAAIYGKSVSFPEKPLIESAKAAADSLEVAIDSDK
                     VLTYASRIVENVTVKPSPQWLQNLLMNAGIRPINNVVDVTNYVLLYFGQPMHAFDYDT
                     FADHKLLARDAREGERLVTLDGEERVLTTDDIVITVADQPVALAGIMGGKSTEITASS
                     KTVVLEAAVFNGKSIRKTSSRLSLRSESSSRFEKGINHDTLVEALDFAAAMLEELAGG
                     TVLAGRLQAGSLPTNPVEVSTSLDYVNVRLGTALSFTDIEGIFARLGFGISGTAEHFT
                     VSVPRRRWDITIPADLVEEIARIYGYDRLPTTLPEAAGTAAELTKTQALRRQLRGLAE
                     GLGLTEIISYALTTPEKALEFAMKPSQLTELMWPMSVERSVLRQSMVSGMLDTLAYNV
                     ARQQHNLAVYEIGKVFEQEGNPKETLPTELNHFAFAITGLVADKDFQTQAQAVDFYHT
                     KGILECLFDKLGLSVDYIPTKEMASMHPGRTARIQLGDQVIGFVGQVHPQAAKAYHIP
                     ETYVAELDLTAIEAALPAHHAFVEITKYPAMVRDIALLVDASTSHQAILSAITSAKVK
                     RLTEIKLFDIYAGAIIAAGKKSMAYSLTFQNPTDNLTDEEVAGYMEKITKALVEKVGA
                     EVR"
     gene            7520..8596
                     /locus_tag="TV188_001354"
     CDS             7520..8596
                     /locus_tag="TV188_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1534704.1"
                     /translation="MFLALNEIKQAKLRYGLIMGLLCLVAYLMFFLSGLAFGLMQENR
                     SAVDSWQADTVLLSKDADANLSLSSLKTSQLKEIKADEVTPLAQLNTVAWSTQAPTEE
                     DKEKISFFGIERESFLKPTITKGRLFKSDKEVVIDQSLAEKGGFKLGDQLRVSASNQT
                     YTIVGYTKNASFNVSPVAYLNLTAFQGLLYGQEAGAQDPNVNAFIIKGKLADYPKEEL
                     QQLTIGDFINKLPGYSAQLLTFGFMIGFLVLISAIIIGIFMYVLTIQKAPIFGIMKAQ
                     GIANRTIANAVLSQTFVLSLLGSSLGLLGTWLSSLVLPATVPFQSNWYLYALILVAMV
                     VFAVLGTLFSVFTIVRIDPLEAIG"
     gene            8606..9310
                     /locus_tag="TV188_001355"
     CDS             8606..9310
                     /locus_tag="TV188_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534705.1"
                     /translation="MTVLAFKQVTKSFKDGDQTIEALKKTDFAIKAGEFVALIGPSGS
                     GKSTFLTIAGGLQTPSSGQFLVNGKDYTNLSEKERSKLRFKDIGFILQASNLIPFLTV
                     KQQLELVDKLTKHKQEAKRQQLFEDLGIAKLANKLPQDLSGGERQRVAIARALYHDPV
                     IILADEPTASLDTEKAFEVVELLAKESKEKNKAIIMVTHDNRMIDYCDKVYRMQDGQL
                     SQDNHHIASNAAMTQN"
     gene            9649..10773
                     /locus_tag="TV188_001356"
     CDS             9649..10773
                     /locus_tag="TV188_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEL1534706.1"
                     /translation="MAKKEMKFYLRKSAFGLASVSAALLVGAAAVSADSVESAGPVAV
                     AVTDSLDSEAAATKAEADLVAAKADLAAAEVAITAAKAEFDTAQADLATAEATIAELE
                     QKIPELEKKIQEAQEKLNYENRPSPKRVGSDDEDDTVARKLMSEKEALKAELQKTKEA
                     LDTAKRAYAGIEERKQVAATKLDAANKAFAGVEEKHAQAMAAFGAAFAAYKEAVKAEL
                     KAAGASDFYTKKIDSADTVDGVKTLREMILDSIAKPEVEPEAKPEPKPEPKPEPKPEP
                     KPEPKPEPKPEPKPEPKPEPKPEPKPEPKPEPKPKPQPKPAPAPKPEAKKEEKKAAPK
                     QDTNKLPSTGEATNPFFTAAALAVMAGAGVAAVSTRRKEN"
     gene            complement(10935..11528)
                     /locus_tag="TV188_001357"
                     /pseudo
     CDS             complement(10935..11528)
                     /locus_tag="TV188_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622734.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            11597..13570
                     /locus_tag="TV188_001358"
     CDS             11597..13570
                     /locus_tag="TV188_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HEL1534707.1"
                     /translation="MKQLTKIVSVVLLLVFTLSASLHKVRATNLSDNITSLTVASSSL
                     RDGERTTVKVAFDDKKQKIKAGDTIEVTWPTSGNVYIQGFNKTIPLNIRGVDVGTLEV
                     TLDKAVFTFNQNIETMHDVSGWGEFDITVRNVTQTTAETSGTTTVKVGNRTATITVTK
                     PEAGTGTSSFYYKTGDMQPNDTERVRWFLLINNNKEWVANTVTVEDDIQGGQTLDMSS
                     FDITVSGYRNERFVGENALTEFHTTFPNSVITATDNHISVRLDQYDASQNTVNIAYKT
                     KITDFDQKEFANNSKIWYQILYKDQVSGQESNHQVANINANGGVDGSRYTSFTVKKIW
                     NDKENQDGKRPKTITVQLYANDQKVNDKTIELSDTNSWQASFGKLDKYDSQNQKITYS
                     VKEVMVPVGYQSQVEGDSGVGFTITNTYTPEVISITGQKTWDDRENQDGKRPKEITVR
                     LLANDAATDKVATASEQTGWKYTFTNLPKYKDGKQITYTIQEDPVADYTTTIQGFDIT
                     NHHEVALTSLKVIKVWNDKDDYYHKRPKEITILLKADGKVIREHQMTPDQQGKWEYTF
                     DQLPVYQAGKKISYSIEEKQVAGYQAPVYEVDEGLKQVTVTNTLNPSYKLPDTGGQGV
                     KWYLLIGGGFIIVAILVLISLYQKHKRHNMSKP"
     gene            13594..15036
                     /locus_tag="TV188_001359"
     CDS             13594..15036
                     /locus_tag="TV188_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HEL1534708.1"
                     /translation="MKTIKLILTSLLVTFLTMLSGKAFADTASYTITVEGATAGHTYE
                     AYQIFKGDLFDSTLSNITWGGGVTPFEFDGSKDAAKIAEGLKEANAAAFAKEAGKHLT
                     ATIAGTGTHAITVNEAGYYLIKDKNDSQTGKHDAYTSFVLKVVKNTSFKPKSAIPTVL
                     KKVKDRNDKTGLETGWQDSADYDKNDKVPFQLTATLPSNYDAFQEYYLEFVDTLSKGL
                     SYNKDAKVYVVNGDTRQDITNSFTVSEDGSSFKINNLKAVQGVTITATSKIVVEYTAT
                     LNDQAAIGKKGNPNEVALKYSNDPNALGKGEESPKGETPKDKVIVFTYKTIINKVDQD
                     QKALKGAGFTLYKLVKGDNGEEKYQIVQEIKAGDTTSFEFVGLDAGDYKLSETTTPGG
                     YNTIADVMFSIVAQHETESDDPQLTSLTVDKATGFTADTEAGTVSATIVNKKGSILPS
                     TGSIGTTMLYVFGVMLMTISTLFIFRQKQQ"
     gene            15117..15926
                     /locus_tag="TV188_001360"
     CDS             15117..15926
                     /locus_tag="TV188_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HEL1534709.1"
                     /translation="MKKSVIFWSVILVAGCLIVLYPTLSNYWNAQHQSQLIADYVSST
                     QALRHKDSQLMLEAANQYNQQLKANHDPDLTLTDSEAEAYQQQLDLTNTGIMAYIDIP
                     KVHERLPIYHGTDEEILQVAIGHLAGTSLPVGGKGTHAVISGHRGLPSAKLFTNIDKL
                     RINDTFTITSLNRTMTYQVDKIATVLPDDVSLLRIEEGKDLVTLVTCTPYGVNTHRLL
                     VRGHRIKTATPTAARGSQKPSRLILWLLLISALGLSLVLIGTWRWRRRSKA"
     gene            16238..17395
                     /locus_tag="TV188_001361"
     CDS             16238..17395
                     /locus_tag="TV188_001361"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678097.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1534710.1"
                     /translation="MMKKQSFTHSRKPKFGMRKLSIGLASCMLGMMFLTTGHVSGEVV
                     EVWPNGQNPNGKIEILSQTEHSEHLQKLRDIEDFQAQKQADHVRYTKWLDGVTVDEHE
                     FRKIKEYDTEYYVTPLLSGKGYYDINKDFNQDSDKCAAAVAANMFHYWFDRNRDSINR
                     FLSQSPGENGVIKLENEKTIEVSKFLETYRSDGDYLDKSPFFDLISNSFKGPVWANKL
                     LDAYINGYGYIHKFAKNTPHSKNNNSKFNFFKKVFDGNLLTDIHQIFDYNTFSDKLSE
                     ALYTGKAIGLAYGPGDLRRSLGHIISVWGADLDDQNRVVAIYVTDSDDKKLTIGNERV
                     GLKRYKVSSDDQGRARLTTRDKDNTGGEIRSIETLDMGTQEWADYFNKTEK"
     gene            17481..>18217
                     /locus_tag="TV188_001362"
     CDS             17481..>18217
                     /locus_tag="TV188_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1534711.1"
                     /translation="MLTNQTGYRHRLSKQKLPISMVSCLLGMGVLTSPTLISADDSSP
                     TIIIKSGAGMTIDPQLPKTLLSKPEEKPEETPKLPDERHYGDDVRPEETPKLPDERHY
                     GDDIKPEEMPKLPDERHYGDDIRKPKPEDTPKPPNESGQGNDLKEDLELKKQRRELTE
                     QLRALKTIEEVLEFLRKPIPGFVTDEDWNFLVSFVEKGPENKTFEVDKLKLLEIFSTS
                     QGHRVWLGYLILEEPMPKPEPKPEPEA"
BASE COUNT         5649 a         3670 c         4106 g         4792 t
ORIGIN      
        1 taattattcg tccaactttt tgggggcagt acatttgtta gacttttgat ataataaagc
       61 tatggaagta attagaactc ttttaatgtt tttcagccat ttattattta ttggcattag
      121 ttatcagcta ctcattagcc tagttgattg gtcaaaattc attcattacc gaccagagaa
      181 tatgggaagg cttcgcttgc ttgtcctttt tttggcaatt gcctcaggct atttagttag
      241 tcgctttatg ctggaattaa ttcaaatcag tcagtatctg ctgtatgatt tccactagag
      301 taggcagtca ggaagtatga tataatatta gtacgatgac cagtaggaaa tggagaagct
      361 tgtggataaa ataatcatag aaggtgggag cacacgttta gagggagagg taacgatcga
      421 aggcgctaaa aatgccgttc ttcctttact agcagctact atcctcccct caactggaaa
      481 gactgtcttg agaaatgtgc cgattctctc agatgttttt acgatgaact atgttgtgcg
      541 tggcctaaat attgacgtcg actttgatga ggctgccaac cagattacag ttgatgcctc
      601 aggggacatt ttagatgttg ccccgtacga gtatgtcagc caaatgcgcg cctcaattgt
      661 ggttttaggc ccgattttag ctcgtaatgg ccatgccaag gtatcgatgc ctggaggctg
      721 tacgattggc agtaggccga tcgatttgca tttaaagggc ctagaggcta tgggcgctga
      781 gatcacccag cagggtggtg acatcactgc aaaggctgag cgcctaaagg gggcaatgat
      841 ctatatggat ttcccatcag tgggggctac gcaaaatttg atgatggcag cgacccttgc
      901 tgatggtgtg acagtcattg agaatgctgc tcgcgagcct gagattgttg acctagccca
      961 gctgctcaac aaaatggggg ctaaggttcg tggggcaggt accgaaaccc tgaccataac
     1021 gggtgtcacc agtctatgtg gggttgagca tgatgttgtt caggatcgta tcgaagcagg
     1081 tacctttatg attgctgcag caatgacctc cggtaatgtg ctgattagag atgctgtatg
     1141 ggagcataat cggcccttga tttctaagct catggaaatg ggagtgtctg ttgtcgaaga
     1201 ggatgcaggc attagggtgc aggctgatgt gactaaacta aggcctgtca ctgttaaaac
     1261 tcttcctcac ccaggctttc caacagatat gcaggctcag tttacagccc ttatggccat
     1321 tgttaaggga gaatctacga tggtggaaac agtctttgaa aatcgtttcc agcacctaga
     1381 agaaatgcga cgcatgggct tacaatctga ggtattgcgt gatacagcta tgattcatgg
     1441 tggtcacgaa ttacagggag cgcctgtgat gtcaacagac ctgcgagcta gtgcagccct
     1501 catcttaacg ggaatggttg ccaaaggcag gaccactgtg aataaattga accatttaga
     1561 tcgtggctat tatcagtttc atgaaaagct tgccaagcta ggtgccaaca ttcagcgaat
     1621 tagtgaggag tagtcaatga ctaatggttg gagatatgtc ataaatcagc taatgctaat
     1681 catagctatt ggactgctcg gactcttttg tctggcgctg ggactaatga ttggctatag
     1741 ccttatcggt gatggccaaa atcctttagc gattttatcg ccagataagt gggctgagct
     1801 gattcataaa tttacgggaa agtaggcatg gcctgctttt tatgataaga ggaaagatga
     1861 tcaaaaagaa gaaagacatc aggctgctta atgccttttt agcgctcttg cttgttcttg
     1921 gaacaggtta tttggcagga catgatgacc tagcagctga taacccgatc aagcaggtct
     1981 accaaaggat tcttggctct gacacgcagc aagccgggct accaaaggca agccgagact
     2041 gggacactcc ctccaaggcc ttggcagatt cggtcatgac agccaccatc aaacagcaat
     2101 taggtgatgt gattacttgg aatggcactg gtgcctatat cattaaccat aataaaacga
     2161 cgctaaatgc aaaggtagct agtctcccct atgccaataa taaaacaaag atggtacaag
     2221 ggcaaagcgt tcctaccgta gccaatgccc tgctaaccaa gtcaacccga caatatcaga
     2281 agcgcaatga cactggaaat ggctatagct catggaagcc tgctggctgg catcaggttc
     2341 aggggttaaa gggaaggtat agtcacgcag tggatagagg gcatcttcta ggctatgcgc
     2401 ttgttggcgg gctaaaaggc tttgatgcct caatggctaa tcctagtaat atcgctactc
     2461 aaaccgcatg ggctaaccaa gcagctaacg agagatcaac cggacaaaac tattatgaaa
     2521 caaaaattcg caaagcccta gatagcaata agcgtgtccg ctatcgtgta actttgcttt
     2581 atgagggaaa taatctctta gcaagcggca gtcatcttga ggcaaagtca tcagatggta
     2641 gcttagaatt taacgtcttt atccctaatg tacaggctgg attacagatt gattatcaaa
     2701 caggtcagat cactgtagct tcttcccagc cttagtgagg cacatcacat ggcaaaagct
     2761 gatcacgtag ctagccatca tggcagagaa gcattagtcc ttgtagtccc tcaaagaaag
     2821 gtgctaacaa tatttggtct tgtggcttta gtagaaaaac agataggtcc tttagtcgaa
     2881 gcaccaagca tgccagctcc tgattaggac aaatgtcaag gctaagcggt ggtaagttaa
     2941 agtctcacaa aagacaagac tggacttttg gctatagtcc tttatgactg atgccagctg
     3001 ataatggctc aagatgattg aggtttctag caatgcttgt ggctagccta tcgtcttagt
     3061 tagcgctgat tgatgagatg ttgaacagtt cttgactaaa agcatcccta cccttacgcc
     3121 tacgtcctgg ttagtgaaga aataagcatt gtcataaagg catttttttg atacaataaa
     3181 agtaattgaa tagcagtcta tgagactagt actaataggg aagttaatag ggaatggggg
     3241 tcgtgactgg aagccttctt aatgaaacga ttaggaattc actcaatcaa ggacgaggta
     3301 attaaggtct gacttgctca gatgaaaacg gatggtaccg cgtgtcaacg ctccgcttta
     3361 gataggagcc ttgatacgcc ttttttgatg acgtgctgtt actattagct atttaatcac
     3421 aagcaagcac tagccagcca aaagtaagtg atcactataa gcatagaaag ataggagctg
     3481 tagcttatct agaaaagcaa gggtgatcag tcgtccgccc aaaagtcttt cttagctttt
     3541 gtgatgtgac tagctgacct agctgctcac agcttagcct aaaaggccta ttagcacaag
     3601 gactgccagc attaatgcaa tcattttcca aacagaaggg aatatcatgg atttacaagc
     3661 acaattagaa gaactgaaaa ccaagacaca agaagcgctc aagcagctaa atggtgacca
     3721 cagcaaggaa ttacaggagc tgcgggttgc tgtccttggg aaaaaaggaa cgcttaccga
     3781 actgctcaag ggactaaagg atctctcaaa tgacctgcgt cctgttgttg gcaaacaggt
     3841 caatgagctt cgtgactttt tgacccaagc ctttgaagag caggctaagg tggttgaggc
     3901 agcaaagatt caggccaagc tagattctga aagcattgat gtgactttgc caggccgtca
     3961 gatgaagcag ggctatcgac atgtgctcac tcaaatcagt gaagaaattg aggacatttt
     4021 cttgggcatg ggctttcaaa ttgttgatgg ctttgaggtt gaaaaggatt attataattt
     4081 tgaacgcatg aaccttccaa aggatcatcc ggctcgtgat atgcaagaca ccttctatat
     4141 cacagaggat attttgctgc gcacccacac cagtcctgta caggcacgaa cactggacca
     4201 gcatgatttt tcaaaggggc ctctcaagat gatttcacct ggacgtgttt tccgtcgtga
     4261 caccgatgat gccactcatt ctcatcaatt tcaccaaatt gaaggcttag tcgttggtaa
     4321 gtctatttct atgggagact tgaaggggac tcttgagatg atcattaaaa agatgtttgg
     4381 taaggagcgt aagattcgcc tgcgcccatc ctatttccct tttactgagc catctgttga
     4441 ggttgatgtc tcatgcttca aatgtggtgg taaaggctgc aatgtctgca aaaaaacagg
     4501 ctggattgaa attcttggag ctggtatggt gcacccaagc gttttagaaa tgtcaggtgt
     4561 gaatgcgcag gagtattcag gctttgcctt tgggcttggt caagagcgca tcgccatgct
     4621 gcgctatggt atcaacgata ttcgaggctt ctaccaagga gatagtcgct tttctaagca
     4681 gtttaagtaa tagtgatcat atggtcaaaa accaaatcat cagtttgaaa aaagaactga
     4741 cgctcaatct ggagctgttc tttggattag aatcagaaag gaaaaagacg ggtaaagagc
     4801 aaagaagtga ttggctagct tatctcaagc aggtgctagg cagatctctc atcagcgctc
     4861 actactctat tgaaggctta tgttagtatc ttataaatgg ttgaaaaaat tagttgacat
     4921 tgatgtctca ccggccgagc tagctgaaaa aatgtcaaca acaggtatcg aagtagaagg
     4981 catcaccagc ccctctgaag gtttatcaaa gctagttgtt gggcatattg tctcatgtga
     5041 cgctgttcca gaaacgcacc tgcacctttg tcaggtcaac acaggagatg atgagcttcg
     5101 tcaaattgtc tgcggtgcac ctaatgtcaa agcagggatt aatgtgattg ttgcgctgcc
     5161 tggagctcgt attgcagaca attacaagat taaaaagggt aaaatacgcg gtatggagtc
     5221 tcttggcatg atctgctcac ttcaggagct tggcttacca gatgcgatta ttccaaaaga
     5281 tttttcagaa ggtatccaga tcctaccgga aacagcagca gcaggtgata gcattttccc
     5341 ttaccttgat ttagatgaca atatcattga gctttccatc acacctaatc gtgctgatgc
     5401 cttatcaatg cgtggtgttg cccatgaggt ggcagctatc tatggcaagt cagtgtcatt
     5461 tccagaaaag ccccttatcg aatccgctaa agcagcagct gatagtctag aggttgctat
     5521 tgactctgac aaggtgctga cctatgctag tcgtattgtt gaaaatgtca ccgtcaagcc
     5581 aagtccgcaa tggctgcaaa atcttctgat gaacgctggc attcgtccaa tcaacaatgt
     5641 tgttgatgtg accaattatg tcttgctgta ttttggtcag ccaatgcatg cctttgatta
     5701 tgataccttt gctgatcata agcttttagc gcgtgatgcg cgtgagggag aaaggcttgt
     5761 cacccttgat ggagaagagc gtgtgctaac cacagatgac attgttatta ccgtagcaga
     5821 ccagccagtg gctctagctg gtattatggg aggcaaatca acagaaatca ccgcctcctc
     5881 aaagacagtg gtgcttgaag cagcagtctt taatggcaaa tcaatccgta aaacaagcag
     5941 tcggctaagt cttcgttcag aaagctcatc acgctttgaa aaagggatta accatgacac
     6001 gcttgtagag gccttagatt ttgcggcagc catgctagaa gagctagccg gtgggactgt
     6061 tttagcaggg cgcttgcagg caggctcact gcctaccaat ccggtagagg tttcaaccag
     6121 ccttgattac gtcaatgtcc gcttgggaac agccttgagc tttactgata ttgaggggat
     6181 ttttgcaagg cttggctttg gtattagcgg aactgctgaa cactttaccg tttcagtgcc
     6241 acgacgccgg tgggatataa caattccggc tgacctagtc gaagaaattg cccgtatcta
     6301 tggctatgat cgattgccaa ccacattacc agaagctgct ggcacagccg cagaattaac
     6361 caaaacacag gcccttcgtc gtcagctgcg tggtcttgca gagggactgg gtttaacaga
     6421 aatcatttcc tatgctctaa caacacctga aaaggccctt gaatttgcaa tgaagccaag
     6481 ccagttaaca gagctgatgt ggccaatgtc agtcgagcgc tctgtccttc gtcaaagcat
     6541 ggtatcaggt atgcttgaca cccttgccta caatgtggca cgtcaacagc ataaccttgc
     6601 cgtttatgag attggtaagg tctttgagca agagggcaat cccaaggaga cattaccaac
     6661 agagcttaat cactttgcct ttgctatcac aggcttagta gcagacaagg attttcagac
     6721 acaagcgcaa gcggttgatt tttaccatac taagggaatc ctagagtgtc tctttgataa
     6781 gctaggactg tctgtggatt atatcccaac aaaggagatg gcgagcatgc acccaggacg
     6841 taccgcacgt attcagctag gagatcaagt gattggcttt gttggtcagg tgcacccaca
     6901 ggctgctaag gcttatcata tcccagagac ctatgttgca gagcttgacc tgactgctat
     6961 agaggcagct ctaccagctc atcatgcctt tgtggaaatc accaaatacc cagctatggt
     7021 aagggatatt gccttattgg ttgatgcctc aaccagtcat caagccattc tttcagcgat
     7081 cacgtctgcc aaggtaaagc gtctaacaga gattaagctc tttgacattt acgcaggagc
     7141 aattattgcg gccggtaaaa aatcaatggc ctatagcctg accttccaaa atccaacaga
     7201 caatctgact gatgaggagg ttgccggcta catggagaaa atcaccaagg ccttggtaga
     7261 aaaggttggt gcagaggtga gataaggacg cttctaatga ctagctacct aaaaaaagct
     7321 catttcaaag gcttagctgc aattgttctg ttgcggctga gctttttttg atgcttagac
     7381 tgtccttatc ctatgctagt tgcagcaagg gtttagagat gattttattt aaattatcag
     7441 tcaaaaatat tttttctaat caaattccta gctttatctg atctcctctg ctatactgtg
     7501 caataagtaa ggagattata tgtttttagc cctaaatgaa ataaaacaag ctaagctcag
     7561 atatggcttg attatgggac tgctctgttt agtagcctat ttgatgttct ttttatccgg
     7621 tttagccttt ggattaatgc aggaaaatcg ctcggcagtt gacagctggc aggcagatac
     7681 agttcttttg tcaaaggacg ctgacgccaa tctcagccta tcctctttaa agaccagtca
     7741 gcttaaggag atcaaggctg atgaggtcac tcccctagcc cagctgaata cagttgcttg
     7801 gtcaacccaa gctccaacag aagaagacaa agaaaaaatc agcttttttg gcattgagag
     7861 agagtccttt ctcaagccta caatcacaaa aggaaggcta tttaagtcag acaaagaggt
     7921 ggtgattgat caaagccttg ctgagaaagg aggctttaag cttggagatc agctgcgggt
     7981 atcggcctct aaccagacct ataccatcgt tggctatacc aagaatgcta gctttaacgt
     8041 gtcacctgtt gcttacctca acctgacagc ctttcagggc ttactgtatg gtcaagaagc
     8101 aggcgcacaa gacccaaatg ttaatgcctt tattatcaaa ggcaagctag ctgactatcc
     8161 caaggaagag cttcagcagc taacgattgg cgacttcatc aacaagctgc cgggctatag
     8221 tgcacagctc ttgacctttg gctttatgat tgggttttta gtgttaatct cagccattat
     8281 cattggtatt tttatgtatg tgctgaccat tcaaaaggca ccaatctttg gtatcatgaa
     8341 ggcacaaggc attgctaatc gtaccattgc aaatgctgtg ctatcacaaa cctttgtcct
     8401 aagccttttg ggcagcagcc ttggcctact aggcacctgg ctaagctcgc ttgtcttacc
     8461 agcaacagtt ccctttcaga gcaattggta cctatatgcg cttattttag ttgctatggt
     8521 agtctttgca gtattaggca ccctcttttc agtctttacg attgttagaa ttgaccctct
     8581 agaggccatt ggttaggaga agaatatgac agtattagca tttaagcagg tcacaaagtc
     8641 ctttaaggac ggtgatcaga ccattgaagc cctgaaaaag acggattttg cgattaaagc
     8701 aggcgagttt gtcgccctta taggtccatc aggctcaggc aaatcaacct ttctgaccat
     8761 tgcaggtggt ctacaaacac caagctcagg acaattttta gtcaatggca aggattacac
     8821 caacctatct gaaaaggaac gatcaaaact acgctttaag gacattggct ttatcctgca
     8881 ggcttctaat ttgattccat ttttaaccgt caaacagcag ctagaattag ttgacaagtt
     8941 gaccaagcac aagcaggaag caaagcgtca gcagctcttt gaggacttgg gaatcgctaa
     9001 gctggctaat aagctgcccc aagatttatc cggtggcgag cgtcagcgtg ttgccattgc
     9061 cagagcccta taccatgatc ctgtgatcat tttagcagat gagccgactg ccagtctgga
     9121 tactgaaaag gcctttgagg tcgttgaact tctagctaaa gaaagcaagg aaaaaaacaa
     9181 ggcaattatc atggtaaccc atgataaccg tatgattgac tattgcgata aggtctatcg
     9241 catgcaggac ggccaattga gtcaagacaa tcatcatata gctagcaatg ccgcaatgac
     9301 tcaaaactaa tcgaatagga aaagctctgc tctagcgata tagcagggct ttttagctgc
     9361 tctaaattat ctcaaaagtt ccttttactg atatttaata ttttctgtat ttttaattta
     9421 tagaaaaata aagaaacatg ctgagagttg atcaaaacac ttactatact tacgatgaca
     9481 agtaacttgc taaagtaatg gttgacatat aattgtaaaa aaacagaaat aaaaaaaaaa
     9541 cggtttaata ttgacctaat tggcaataac gtttacaata aaggtataat tatctgccgt
     9601 tgataattag gagacatcat gtctagataa aaacaaaagg ggaataaaat ggcaaaaaaa
     9661 gaaatgaagt tttaccttcg taaatcagcc tttgggctag cttcagtatc agcagccctc
     9721 ttggttggtg cggcagctgt atcagcagat tctgttgagt cagctgggcc tgtagcagtt
     9781 gctgttacag atagtttaga tagtgaagcc gcagctacaa aggcagaagc tgatctagtt
     9841 gctgcaaaag cagacctagc agcagcagaa gtagcaatca cagctgcaaa agctgaattt
     9901 gacaccgctc aagcagacct agctaccgct gaagctacta tcgcagagct tgagcaaaaa
     9961 attcctgagt tagagaaaaa aattcaagaa gctcaggaaa aactaaacta tgaaaatcga
    10021 ccatcaccta aacgtgtggg cagtgatgat gaagatgaca cagtagctag aaagcttatg
    10081 tcagaaaagg aagctcttaa ggctgagctt caaaagacta aagaagcgct agatacagct
    10141 aaaagagctt atgctggcat cgaagaaaga aaacaagtag cagcaactaa gctagatgca
    10201 gctaacaagg cttttgctgg agttgaagaa aagcatgctc aagcaatggc tgcatttgga
    10261 gcagcattcg cagcatacaa ggaagctgtt aaggctgaat tgaaggcagc aggtgctagc
    10321 gacttctaca ccaagaagat tgactctgcc gacacagttg acggtgttaa gacactcaga
    10381 gaaatgatct tagactcaat tgctaagcca gaggttgaac cagaggctaa gcctgaacct
    10441 aagccagaac caaaacctga gccaaaacct gagccaaaac cagaacctaa gccagaacca
    10501 aaacctgagc ctaagccaga gccaaaacca gaacctaagc ctgagcctaa gccagaacca
    10561 aaaccagaac ctaagccaaa acctcaacct aaaccagctc cagctccaaa acctgaagct
    10621 aagaaggaag agaagaaagc agcgcctaag caagacacca acaaattgcc atcaacaggt
    10681 gaagctacaa atccattctt caccgcggca gctcttgcag ttatggcagg tgcaggcgtg
    10741 gctgcagtgt caacaagacg caaagaaaac taagccttat accccagtgg taaagcttga
    10801 gcgagaacaa tttgttctcg cttttttagt gtcttaaaag cacctacagc aatcataggt
    10861 gcttaacaag atatgtctaa cgattgctat cagctgtaga gaataaaaag gagagactaa
    10921 gccttgctca caagctactt agaccgaagg agctttagga tttctatgat ttgctgaggg
    10981 gagtccttac agccgcagct gatccactta atgatgatga cctcaataga ggcaatgtat
    11041 agctcaaaaa catatttttg ggtaacttca ggataatctt gtgattctgc acaattcatg
    11101 aggttggaat aggaaataat atccctaata taatgattaa aaattttata aatattagga
    11161 taataaagga ttaagctttg catgacctcc tgattgtcag agaggtagtt taggattttt
    11221 aaggtaatag ttgtatcaag tgatggggat tggtaaatga tagaggtgat atcatctagg
    11281 taaacgccga tcatttccct atctaagtcc ttcttagagt tgaaataatg ttaaaaggtt
    11341 gttcgactga tattagaagc cttgctaata tctgatacag taatactgtc cttatccttg
    11401 tattgtagta gtcggcagta gcttttaatt atttttttac aagtttgttt atttttatcc
    11461 attgtatcat taactcctta aaattgaaca ttaatgttaa ttttgtacat aatatttttt
    11521 gctaacatta tacaatgatg aacgtgattt gtaaaattaa attttgcaaa tcaataatgt
    11581 aaaaggagga ttttgtttga aacaactgac aaagatcgtt agtgtggtct tgttgctggt
    11641 ctttaccctt agtgctagcc tgcacaaggt tcgggcaact aatcttagtg acaacatcac
    11701 atcattgacg gttgcttctt catcactccg agatggagag agaacgacgg taaaggttgc
    11761 gtttgatgac aaaaaacaga aaatcaaggc aggggatacg atagaggtca cctggcctac
    11821 aagtggtaat gtctacattc agggctttaa taaaaccata ccgcttaata ttagaggggt
    11881 agatgttggt accttggagg tcacgctaga caaggctgtt ttcacattca atcaaaatat
    11941 tgaaacaatg catgatgtct ctggttgggg agagtttgat attactgtta gaaatgtgac
    12001 acaaaccacc gctgaaacat caggaacgac cacagtaaag gtaggcaatc gcactgctac
    12061 tatcactgtt actaagcctg aggcaggcac tggtaccagc tcattttatt ataagactgg
    12121 tgatatgcag cccaatgata ctgagcgtgt gagatggttc ctgctgatta acaacaacaa
    12181 ggaatgggtg gccaatactg ttacagtcga agacgatatt caaggtggtc aaaccttgga
    12241 tatgagcagc tttgacatca ccgtatctgg ttatcgtaac gagcgcttcg ttggggaaaa
    12301 cgctctgaca gagtttcata caacatttcc aaattctgtc attacggcaa cagataatca
    12361 cattagtgtg cggttagatc aatatgatgc ctcacaaaac actgtcaaca ttgcttataa
    12421 gacaaagata acggactttg accaaaaaga atttgccaac aacagtaaaa tctggtacca
    12481 gattttatac aaggatcagg tatcgggtca agagtcaaac caccaagtag ccaatatcaa
    12541 tgctaacggc ggggttgatg gcagtcgcta taccagcttt actgtcaaga aaatttggaa
    12601 tgacaaggaa aatcaagacg gtaagcgtcc aaagactatt actgttcagc tttacgccaa
    12661 tgatcagaaa gttaatgata agaccattga attgagtgat actaatagct ggcaagcaag
    12721 ttttggtaag ctggataagt atgacagtca gaaccaaaaa attacctaca gtgtcaagga
    12781 agtgatggtt cctgttggct accaatcgca ggttgagggg gatagtggag taggatttac
    12841 cattaccaac acctatacac cagaggtcat tagcattacc ggtcaaaaaa cttgggacga
    12901 cagggaaaac caagacggta aacgtcctaa ggagattacg gttcgtttat tggcaaatga
    12961 cgctgcaact gacaaggtag caactgcttc agagcaaacc ggctggaagt atacatttac
    13021 caatctaccg aaatacaaag atggtaaaca gatcacctac acgatccaag aggaccctgt
    13081 ggcagattac accacaacca ttcagggatt tgatattacc aatcatcatg aggtagcctt
    13141 gaccagccta aaggtcatca aggtttggaa tgataaggac gattattacc ataaacgtcc
    13201 caaggagatt accattttgc taaaggcaga tggcaaggtg attcgtgaac atcagatgac
    13261 accggatcag caaggaaaat gggaatacac ctttgaccag ctgccggtct atcaggcagg
    13321 caagaaaatc agctacagca ttgaggaaaa acaggttgct ggctatcaag cccctgtcta
    13381 tgaggttgat gaaggcttga agcaggtcac tgtaaccaac acccttaacc caagctacaa
    13441 gctgcctgac accggaggac aaggagtgaa atggtacctg ttaatcggtg gcggttttat
    13501 catcgtcgca atccttgtac tgatcagcct ttatcaaaaa cacaagcgcc ataacatgtc
    13561 aaaaccataa catgtaatag aggagagaga gctatgaaaa caatcaaatt aatcttgacg
    13621 agcttgcttg tcaccttcct aacaatgctg tcaggaaagg catttgctga tacagcaagc
    13681 tataccatca ctgttgaggg agctacagca ggtcacacct atgaggctta tcagattttc
    13741 aagggtgact tgtttgacag taccctatca aacatcacat ggggaggtgg tgttacacct
    13801 tttgaatttg atggttcaaa agacgctgct aagattgcag agggattgaa ggaagcaaat
    13861 gcagctgcct ttgccaagga agcaggtaag cacttgacag caaccattgc aggaacagga
    13921 acacatgcaa tcaccgttaa cgaggctggc tactacctca tcaaggacaa aaatgattct
    13981 caaacaggca agcatgacgc ctacacctca tttgtcctga aggttgttaa aaataccagc
    14041 ttcaaaccaa aatctgctat cccaacagtc cttaaaaagg tcaaggaccg taatgacaag
    14101 acaggtcttg agacaggctg gcaagattca gctgactatg acaaaaatga caaggtgcca
    14161 ttccagctaa ccgcaaccct accgtcaaat tacgatgcct ttcaagaata ctaccttgaa
    14221 tttgtagata ccttatcaaa agggctaagc tacaacaaag acgccaaggt ctatgtggtt
    14281 aatggagata ctcgtcaaga tattactaat tcatttacag ttagtgaaga tggttcatct
    14341 tttaaaatca ataacctaaa ggctgttcag ggagtaacaa taacagctac cagtaagatc
    14401 gttgtcgaat acactgctac cctcaatgac caagcggcca tcggcaaaaa aggaaatcca
    14461 aacgaagttg ctttgaaata ctcaaacgat ccaaacgctc ttggaaaagg agaggagtct
    14521 ccaaaagggg agacaccaaa agacaaggtt atcgttttca cctataaaac tatcatcaat
    14581 aaggttgatc aagatcaaaa agccctaaaa ggtgcaggct ttacccttta taagctggtc
    14641 aaaggtgata atggcgagga aaaatatcaa atagtccaag aaattaaagc aggggataca
    14701 actagctttg agtttgttgg acttgacgct ggtgattaca agctcagcga aacaacaaca
    14761 cctggcggtt acaacactat tgcagatgtc atgttcagca ttgtagcgca gcatgaaacc
    14821 gagtcagacg atcctcagtt gactagccta accgttgaca aagcaactgg cttcactgct
    14881 gatacagaag ctggtaccgt atccgcaact attgttaata aaaaagggtc tatcctccct
    14941 tcgacaggaa gtatcggaac aaccatgctc tatgtgtttg gagtaatgct aatgacaata
    15001 tcaacgctgt ttatctttcg tcagaaacag caataagatc gtgtgagtag gtaaaaagaa
    15061 gtggatagac gtcttaccaa gacctattca cctctttttt tgatagaggc tatagaatga
    15121 agaaaagtgt cattttttgg agtgtgattt tggtggcagg ctgtctgatt gtcctttacc
    15181 ccacccttag taactattgg aatgcacagc accaatcaca gctcatcgct gactatgtct
    15241 caagcacgca agctttgaga cataaggata gtcagctcat gctagaagca gccaatcagt
    15301 acaatcagca gctaaaagct aaccatgatc ctgatttaac cttgaccgat agtgaggcag
    15361 aagcctatca gcagcagctg gatctgacaa atacaggtat catggcctac atagatattc
    15421 caaaggtgca tgagcggctg ccgatttatc atggcaccga tgaggagatc ctacaggtgg
    15481 ctatcggtca tcttgcaggc acctctttgc ctgtaggtgg caagggaaca catgctgtca
    15541 tctcaggaca tcgagggtta ccctctgcca agctatttac caatattgat aagctgagga
    15601 ttaacgatac ctttaccatc accagtctta ataggactat gacctatcag gtggataaga
    15661 ttgctaccgt tttgcctgat gatgtcagcc tcttaaggat agaggagggg aaggatctgg
    15721 taaccttggt cacctgtacc ccctacggtg tcaacacgca tcggctcttg gtcagagggc
    15781 atcgtatcaa aacagcgaca ccaaccgctg caagaggatc tcaaaagcct agtaggctaa
    15841 tcctctggct cttgctaatc agtgcattag ggctatctct cgtactaata ggcacttggc
    15901 gctggcgtag gaggtctaaa gcatgagcag gctttccaga agcaactaag tcaaatcatc
    15961 aacccttgat aggttactga ggacctatca ggggattttt tagtgctaaa ttgcgactat
    16021 gattaaaaac acagaaatcg tttttttttc ttagtgaccg aaaacgcttt aaaagagcga
    16081 gcatttggag ccttcaaaag tgacatctga gcataacatg ataaaattga cttataaaac
    16141 ctaataaaat gataaaagga ggagagttaa cgacaaaata ttagatattt atttaatttg
    16201 ttgtttttga aaacgtttta taataagaaa ggatagcatg atgaaaaaac aatcattcac
    16261 acactcacgt aaacctaaat tcggtatgag aaaattatct attggccttg cctcatgtat
    16321 gctaggaatg atgttcctaa caacaggaca tgtttctggt gaggtagttg aagtttggcc
    16381 taatgggcaa aatcctaatg gtaaaataga aattctaagt caaactgagc actctgagca
    16441 tttacagaaa ttacgcgata ttgaagattt ccaagctcaa aagcaagctg atcatgttcg
    16501 ttacactaaa tggttagatg gggtaactgt tgatgagcat gaattcagaa aaatcaagga
    16561 atatgacaca gaatattatg taacacctct tttaagtggt aaaggttact atgatatcaa
    16621 taaagatttc aatcaagata gtgataaatg tgctgccgct gtagcggcta atatgttcca
    16681 ttattggttt gatagaaata gagacagtat taatcgtttc ttaagtcaaa gtccaggtga
    16741 aaatggtgtt attaaacttg aaaatgaaaa aacaatagaa gtatcaaaat ttttagaaac
    16801 ttaccgtagt gatggtgatt atcttgataa aagtccgttt tttgacctta tcagtaacag
    16861 ctttaaaggt cctgtttggg caaataagct attggatgct tacattaacg gctatggtta
    16921 tatccataaa tttgctaaaa atactccaca ttctaaaaat aataatagta aatttaattt
    16981 ctttaaaaaa gtatttgatg gtaatctctt gacagatatt caccaaattt ttgattataa
    17041 cactttttca gataaattaa gtgaggctct ctatactggt aaagccattg gattggccta
    17101 cggacctgga gacttgcgtc gttcactagg tcatattatt tctgtctggg gagctgatct
    17161 tgacgatcag aatcgcgtgg tagctattta tgtaactgat tctgatgata aaaagttaac
    17221 tataggaaat gagagagttg gtttgaagcg atataaagta tctagcgatg atcaaggtcg
    17281 tgctcgtctg acgactcgtg ataaagataa cacaggtggt gaaattcgat ctattgaaac
    17341 attagatatg ggtacacaag agtgggcaga ttacttcaac aagacagaaa aataacaata
    17401 acccctacac atatatgatt actccagata aagcacacag caatagactc agccagtaag
    17461 gaaaggacga taacaaaacg atgctaacaa accaaacggg gtacaggcat agacttagta
    17521 agcagaagct acctatcagc atggtttcct gcttgctagg aatgggggtg ctaacctctc
    17581 caacattaat ctcagctgat gatagttctc ctactatcat cattaaatcg ggtgcaggta
    17641 tgacaattga tcctcaatta ccgaaaactc tcctttctaa acccgaagag aaaccagagg
    17701 aaacacctaa acttccagat gagcgacatt atggtgatga tgtcagaccg gaagaaacac
    17761 caaagcttcc agacgagaga cattatggtg acgatataaa accggaagag atgccaaagc
    17821 tcccagatga gcgacattat ggtgatgaca tcaggaagcc gaaaccggag gatactccaa
    17881 agccacctaa tgaaagcggt caaggtaatg acttaaaaga agatttggag cttaaaaagc
    17941 aacgtcgaga gcttacagag cagcttcgtg ctttaaaaac tattgaggaa gttttagagt
    18001 tcctgagaaa accaattcct ggatttgtaa cagatgaaga ttggaatttc ttagtatcat
    18061 ttgtagaaaa aggcccagaa aataaaactt ttgaagtaga taaattaaaa ttactagaaa
    18121 tcttctcaac ctcacaaggt catagagttt ggttaggtta ccttattctg gaagagccaa
    18181 tgcctaaacc ggaacctaag ccagagccag aggctaa
//
LOCUS       DARYYD010000038        17855 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.038, whole genome shotgun sequence.
ACCESSION   DARYYD010000038 DARYYD010000000
VERSION     DARYYD010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17855
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.038"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(220..1320)
                     /locus_tag="TV188_001363"
     CDS             complement(220..1320)
                     /locus_tag="TV188_001363"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1534712.1"
                     /translation="MISSLHRPTVARVDLEAIRANIDHIHQHIPKKVRTYAVVKANAY
                     GHGAVAVSKAVEDQVDGYCVSNLDEALELRQAGIDKEILILGVILASELQLAIKHQLT
                     ITVASLEWLELAKKESVDFSQLHVHVKVDSGMGRIGVRSLAEANQLISILSDMGVQLD
                     GIFTHFATADDSDHAMFDKQLTFFKQLVEQLDKRPALVHASNSATSLWHSETIFNAIR
                     LGIVIYGLNPSGNSLSLPCPLKEALSLESRLVHVKQIQAGDSVGYGASYVAAEPEYVG
                     TLPIGYADGWTRNMQGFKVLVEGEFCDIIGRVSMDQLTIRLPKAYPIGTKVTLIGQQG
                     KQVITATDVADYRGTINYEVLCLLSDRIPREY"
     gene            complement(1317..1673)
                     /locus_tag="TV188_001364"
     CDS             complement(1317..1673)
                     /locus_tag="TV188_001364"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEL1534713.1"
                     /translation="MIVGHGIDLQDISAIEKVYLRNARFARKVLTDKELALFEQFSHH
                     RKMTYLAGRWAGKEAFSKAMGTGIGQLTFQDIEIINDSKGRPVITKSPFQGKAFISIS
                     HSGGYVQASVILEDLA"
     gene            complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TV188_001365"
     CDS             complement(1789..4317)
                     /gene="secA"
                     /locus_tag="TV188_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEL1534714.1"
                     /translation="MSNILRKVIENDKGELRKLEKIAKKVESYADYMESLSDKDLQAK
                     TPEFKQRYQNGETLEQLLPEAFAVVREAARRVLGLYPYRVQIMGGVVLHNGDVPEMRT
                     GEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
                     PAEKREAYLCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEAR
                     TPLIVSGAVSSETNQLYIRADMFVKTLDSVDYIIDVPTKTIGLSDSGIDKAESYFNLS
                     NLYDIENVALTHFVDNALRANYIMLLDIDYVVSEEGEILIVDQFTGRTMEGRRFSDGL
                     HQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIP
                     IPTNRPIARIDHTDLLYATLNSKFKAVVADVKARYEKGQPVLVGTVAVETSDLISKKL
                     VEAGIPHEVLNAKNHFKEAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGTDRIKAFLDRMNNDD
                     EDIVIKSRMLSRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANR
                     DLGPEIKAMIKRTIDRAVDAHSRTNRKDAIDAIVTFARTSIVPEETIGAKELRGLKDD
                     QIKDKLYQRALEIYDKQLSKLRDQDAILEFQKVLILMIVDNKWTEHIDALDQLRNAVG
                     LRGYAQNNPVVEYQSEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERAIQYATTTAA
                     QNIQSQAIGADFDSSADFSRVERNDACPCHSGKKFKNCHGRKAF"
     gene            complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TV188_001366"
     CDS             complement(4693..5637)
                     /gene="manA"
                     /locus_tag="TV188_001366"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEL1534715.1"
                     /translation="MSEPLFLTSCMHDKIWGGTKLREVFGYELPTETTGEYWAISAHP
                     NGVSTVSSGSYQGQRLDQLYAERPELFGNPKEKVFPLLTKILDANDWLSVQVHPDDAY
                     GLAHEGELGKTECWYIISAEEGAEIVYGHHASSKQELRAMIEAGNWEELLTRVPVKAG
                     DFFYVPSGTMHAIGKGILILETQQSSDTTYRVYDFDRRDAEGQLRELHIEKSIDVLTI
                     GKPENSTPATLELEHLVSTCLVSNPFFTVYKWEIDQAVSMKQSAPYLLVSVLAGQGSL
                     TIDQAVYELQKGMHFILPNDVTSWSFDGQLEMIVSHPN"
     gene            complement(5753..6637)
                     /locus_tag="TV188_001367"
     CDS             complement(5753..6637)
                     /locus_tag="TV188_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEL1534716.1"
                     /translation="MKTLLGSIEAGGTKFVCAVGDRDFAVVDKVQFPTTSPKETIERT
                     IAYFKQFEADLASIAIGSFGPIDIDPKSATYGYITTTPKPGWANVDLLGQLTAAFAIP
                     FYVTTDVNSSAYGEAISRPDVDSLVYYTIGTGIGAGAIQKGEFIGGLGHTEAGHTYVM
                     QHLDDVANAFLGVCPFHRGCLEGMAAGPSLEARAGIKGELLDQKAAVWDIQAFYIAQA
                     AVQATLLYRPQVIVFGGGVMAQEHMLVRVQEAFTRLINGYLPVADVREYLVTPAVAGN
                     GSATLGNFALAKLIAEKS"
     gene            complement(6994..10050)
                     /locus_tag="TV188_001368"
     CDS             complement(6994..10050)
                     /locus_tag="TV188_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEL1534717.1"
                     /translation="MEKQVLVKKTLKCVCAAALMVAILAAQHDSLIRVKAEDKVVQTS
                     PSVSAIDDLHYLSENSKKEFKEGLSKAGEVPEKLKDILSKAQQADKQAKVLAEMKVPE
                     KIAMKPLKGPLYGGYFRTWHDKTSDPAEKDKVNSMGELPKEVDLAFVFHDWTKDYSFF
                     WQELATKHVPTLNKQGTRVIRTIPWRFLAGGDHSGIAEDTQKYPNTPEGNKALAKAIV
                     DEYVYKYNLDGLDVDIERDSIPKVNGKESNENIQRSIAVFEEIGKLIGPKGADKSRLF
                     IMDSTYMADKNPLIERGAQYIDLLLVQVYGTQGEKGDWDPVARKPEKTMEERWESYSK
                     YIRPEQYMVGFSFYEENAGSGNLWYDINERKDDHNPLNSEIAGTRAERYAKWQPKTGG
                     VKGGIFSYAIDRDGVAHQPKKVSDDEKRTNKAIKDITDGIVKSDYKVSKALKKVMEND
                     KSYELIDQKDFPDKALREAVIAQVGSRRGDLERFNGTLRLDNPDIKSLEGLNKLKKLA
                     KLELIGLSQITKLDSLVLPANAKPTKDTLANVLEAYGSAKKEETKAIPQVALTISGLT
                     GLKELNLAGFDRDSLAGIDAASLTSLEKVDLSSNKLDLAAGTENRQILDTMLATVTKH
                     GGVSEKTFVFDHQKPTGLYPDTYGTKSLQLPVANDTIDLQAKLLFGTVTNQGTLINSE
                     ADYKAYQEQEIAGHRFVDSSYDYKAFAVTYKDYKIKVTDSTLGVTDHKDLSTSKEETY
                     KVEFFSPTNSTKPVHEAKVVVGAEKTMMVNLAEGATVIGGDADPTNAKKVFDGLLNND
                     TTILSTSNKASIIFELKEPGLVKYWRFFNDSKISKADCIKEAKLEAFVGHLEAGSKVK
                     DSLEKSSKWVTVSDYSGEDQEFSQPLNNIGAKYWRITVDTKGGRYNWPSLPELQIIGY
                     QLPAADLVMAMLATAEELSQQKDKFSQEQLKELEVKIAALKAALDSKMFNADAINAST
                     ADLKAYVDKLLADRTDQEKVAKAAKVEQPVATDIKENTEPENPKTD"
     gene            complement(10279..12162)
                     /locus_tag="TV188_001369"
     CDS             complement(10279..12162)
                     /locus_tag="TV188_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1534718.1"
                     /translation="MDNHQIAKEVIEALGGRENVRSVAHCATRLRVMVHDEGKINKEK
                     AEAIDKVKGAFFNSGQYQLIFGTGTVNSIYDEVVALGLPAALAGEQKEQVVKSGNAFQ
                     RAIRTFGDVFVPIIPAIVAIGLFMGVRGLLTQPAVMEFFGIHDYGDNFLMYTRILTDT
                     AFVYLPALVAWSAFRVFGGNPIIGIVLGLMLVSNELPNAWVVASGGDVKPLTFFGFVP
                     VVGYQGTVLPAFFVGLVGAKLEKWLHKRVPDALDLLATPFLTFAIMSALGLFVIGPIF
                     HSLENLVLAGTQAVLGLPFGIAGLVIGGVQQLIVVTGIHHIFNFLEAQLVANTGKDPF
                     NAYLTAATAAQAGATLAVAVKTKSAKLKGLAFPSALSALLGITEPAIFGVNLRYPKVF
                     VSGLIGGAAGGWVAGILGIAGTGFGITVLPGALLYLNGQLLQYLVTLLVGLGLAFVIA
                     YIWGFKDKSDQEAPATQVKSEPAQKASAAEELLSPVAGELIDLSSVADPVFSSGSMGQ
                     GVAIKPEGRILCSPVDGRVEAALETGHAYVIKSDKGAEILLHIGIDTVSMAGEGFETF
                     VKVGQMVKAGDALGSFDIARIQQAGLDTTTMLLVTNSADVHAVQILAQGKVTVGSPVI
                     LVK"
     gene            12439..13878
                     /locus_tag="TV188_001370"
     CDS             12439..13878
                     /locus_tag="TV188_001370"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HEL1534719.1"
                     /translation="MDLPRSIRYRPYQEWSKEAYQAIQQKVAQSLWRSHFHIEARTGL
                     LNDPNGFSYFAGSFQLFYQNWPFGAAHGLKQWVHTTSTDLVHFTETKTRLLPDHQNDS
                     HGAYSGSAYPIGDKLFLCYTGNVRSKDWVRHPLQIGAWMDQSGHITKCEQVLIDKPDD
                     VTEHFRDPQLFTYQDQLYAIIGAQNLQQQGIIKLYKANNNDVTSWQFVADLDFDDSGT
                     AYMIECPNLVFIEDKPVLIFCPQGLAKSELDYQNIYPNTYKVFQTFDPKRRKLLGGGP
                     IQNLDFGFEAYATQAFNSPDGRVLAVSWIGLPDIDYPTDKYAYQGALSLVKELRLKNG
                     RLHQAPVPALSKLRDKAQPFQNKKNSSNCYELALTIEAQQATELLLFADTQHKGLKLT
                     VDTCKGQLTIDRSKAGAQYAQEFGAKRSCQIPVNRATLNIYVDKSILEIFVNQGEAVL
                     TSRVFPNEGQSGIELLKGQVSGYYYEMRY"
     gene            13883..14848
                     /locus_tag="TV188_001371"
     CDS             13883..14848
                     /locus_tag="TV188_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1534720.1"
                     /translation="MVAKLTDVAALAGVSPTTVSRVINKKGYLSQKTIDKVNKAMREL
                     GYKPNNLARSLQGKSPQLIGLIFPNISNIFYAELIEHLEIELFKQGYKAIICNSENNP
                     IKERDYLEMLAANQVDGIISSSHNLGIDDYERVEAPIVAFDRNLAPHIPIISSDNFEG
                     GKLAAKTLQKHGCQKMIMITGNDHSDSPTGLRQLGFNYQLKKGADIIKLPNDLSSIRR
                     EMEIKSILATRRPDGIFASDDLTAILIMKVAGQLGIAIPDNLKLIGYDGTAFIEHYFP
                     QLTTIKQPIKEIASLTVEVLLKKIGNEKTSKDYVLPITLLPGGSL"
     gene            complement(15225..15731)
                     /locus_tag="TV188_001372"
     CDS             complement(15225..15731)
                     /locus_tag="TV188_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534721.1"
                     /translation="MKRKILLLMMLLVGVFIFSKRYELYYFFQGKEYLRPNESIELAV
                     RPKYEQIEYSSDLYLESDEKVLLKLEGRDIWSEYIYRRTDSYLSKIGYRYSITEQVIE
                     KYDSTKDNGVVIVEAGHKGATIDGDGLIVPLKGKRKYSVTEDHDYSITITNLSDQPVA
                     FRAIVADR"
     gene            complement(15728..17134)
                     /locus_tag="TV188_001373"
                     /pseudo
     CDS             complement(15728..17134)
                     /locus_tag="TV188_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515913.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17125..17484)
                     /locus_tag="TV188_001374"
                     /pseudo
     CDS             complement(17125..17484)
                     /locus_tag="TV188_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515008.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(17496..17762)
                     /locus_tag="TV188_001375"
     CDS             complement(17496..17762)
                     /locus_tag="TV188_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HEL1534722.1"
                     /translation="MSDTITSSPVAASAAISELVGVDTSRVHQQSVAFSVTKGIAGME
                     KGRQVSNQLLQAVSDFSQAVLIQANKFPQLAAKLEKRDLEEATR"
BASE COUNT         5023 a         4424 c         3375 g         5033 t
ORIGIN      
        1 tgaagcaaaa taaaatgcaa gattttttgt attaatgcct taatactcgg ataaaggtaa
       61 gggccttttc ttattctttt tcttaacccg cagaaaaaca agacctgtct tgatctgctc
      121 tatctatgct gttagcctga ggtctcaaga cctttacagg actaatcatt tgaaagacag
      181 ccttgaggcc agtcaatagt tgagcctagg ctcaatttcc taatattctc taggaatacg
      241 atcactcagc aagcaaagca cctcataatt aatcgtacct ctataatcgg caacatcggt
      301 tgctgtgatt acttgtttac cctgctgtcc aatcaaggtc accttagtgc cgataggata
      361 ggctttaggc aaacgaatgg tcaattggtc catcgacaca cgaccaataa tgtcacaaaa
      421 ttccccttct accaatacct taaagccctg catatttcga gtccaaccgt cagcatagcc
      481 gataggtaag gtcccgacat actctggttc tgctgctaca tagctagctc catagccaac
      541 gctatcccct gcctgaattt gcttcacatg aaccaaacgt gattctaagg acaaggcttc
      601 ctttaaggga caaggtagac tcaagctatt gccgcttgga ttgagtccat agataacaat
      661 accaaggcga atggcattaa aaattgtttc actatgccaa aggcttgttg cagagttgct
      721 tgcatgcact aatgcaggcc tcttatctag ctgctccacc aactgcttga aaaaggtcag
      781 ctgcttatcg aacatggcat ggtcagagtc atctgcggtt gcaaaatgcg tgaaaatccc
      841 gtcaagctgc actcccatat cggataagat tgagatgagc tgattggcct cagcaagcga
      901 cctgacacca atgcgcccca ttcccgagtc aaccttgaca tgcacatgaa gctgactgaa
      961 atcaaccgat tcctttttgg caagctctag ccactctaag ctggccactg ttatcgtcag
     1021 ctgatgctta atggctagct gcaattcact tgctaaaatc acccctaaaa taaggatttc
     1081 cttatcaatg cctgcctgac gtaattccaa ggcttcatca aggtttgata cgcaatagcc
     1141 atcaacctga tcctcaactg ccttggacac tgcaactgcc ccatgaccat aagcattggc
     1201 cttgacaaca gcatatgtcc ttaccttttt aggaatatgc tgatgaatat ggtcaatatt
     1261 tgctcgaata gcttctaagt caactctagc tactgttggt cgatgtaagc ttgaaatcat
     1321 gctaaatcct ccaaaataac acttgcttga acatagcccc cactatgtga aatactgata
     1381 aaggccttac cctgaaaggg agattttgta atgacgggac gccctttgct gtcattgata
     1441 atttcaatat cctgaaaggt tagctggcca atccctgtcc ccattgcctt tgaaaaggcc
     1501 tccttaccag cccagcggcc ggccagatag gtcatttttc ggtgatggga aaattgctca
     1561 aacagcgcta gctccttgtc cgtcaaaacc tttctagcaa atctagcatt tctcaaataa
     1621 accttttcaa tagctgaaat atcctgtaaa tctatcccat gtccaacaat catttgcctt
     1681 tattttacca gccttcactt taatttaggg aaacaaatcc taaacaagga gaagccgaga
     1741 acaaatctca gctcctcaca ggttttcaac atggccatca cgctatcctt aaaaagcctt
     1801 acgaccatga cagtttttaa acttcttacc agagtgacaa ggacaagcat cattgcgctc
     1861 gactcttgaa aaatcagctg atgaatcaaa atcagcaccg atagcctgcg actgaatgtt
     1921 ttgtgctgca gttgttgttg catactgaat tgcacgctcg cgctcctgct catgaatctg
     1981 tgccttcatc atggtacgtg taacatcaaa ttcgatagca ccaatcatat cctgaaacat
     2041 cttgaagcct tcactttgat attcaacaac tggattattt tgcgcataac cacgcaaacc
     2101 aaccgcatta cgaagctggt ctaaggcatc aatatgctct gtccatttgt tgtcaacaat
     2161 catcaaaatc agcaccttct ggaattctaa gatagcgtcc tgatcgcgca attttgataa
     2221 ctgcttatcg taaatctcaa gggcacgctg atagagcttg tctttgatct gatcgtcctt
     2281 gaggccacgc aattccttag caccgatggt ttcctctggg acaattgatg ttctcgcaaa
     2341 agtcacgatg gcgtcaatag cgtccttacg attggtacgt gagtgggcat caactgctcg
     2401 atcaatcgta cgcttgatca ttgccttaat ttcaggacct aggtcacgat ttgctgtgat
     2461 aacatcacga cggttagcgt aaataatctc acgctgctca cgcatcacat catcatactg
     2521 caagacctgc ttacgtgtgt catagttatt accctcaaca cgtttttgag ctgactccac
     2581 ctggcgtgac agcattctgg acttgataac aatatcctcg tcatcattgt tcatacgatc
     2641 caagaaagcc ttaatacggt ctgtaccaaa gcgcctcatc agctcgtcct ctaaggagag
     2701 gtagaattgt gactcccctg gatctccctg acgacctgaa cgcccacgaa gctgattatc
     2761 aatacggcgg ctctcatgac gctctgtccc gataacacaa agcccaccga gctctcggac
     2821 accctcaccg agcttaatgt ctgtcccacg accagccata ttggtcgcaa tcgttaccgc
     2881 accacgctga ccagcattca taataatctg tgcttcttta aagtggttct tagcatttaa
     2941 gacctcatgc ggaatgcctg cttctactag ctttttagaa atcaggtcac tggtctcaac
     3001 agcaactgta ccaactagaa cgggctgccc cttttcatag cgagccttaa catctgcaac
     3061 cactgccttg aattttgaat tcaacgttgc ataaagaagg tctgtgtgat caatacgagc
     3121 aataggacgg ttggttggaa tcggaataat acgcatgttg taaacttcgc ggaattcctc
     3181 ttcctccgtt tttgctgtac cagtcatacc cgccaatttc ttatacatac ggaacatgtt
     3241 ttggtaggta atagaggcac ttgtttttga ttcctcttga atacgaacgc cctcttttgc
     3301 ctcaatagct tggtgtaagc catccgaaaa gcgtcgtccc tccattgtac gacctgtaaa
     3361 ctggtctaca atcaaaatct cgccttcctc gctaaccaca taatcaatat ccaaaagcat
     3421 gatataatta gcacgaaggg cattatccac gaagtgggtc aaggcaacat tttcaatatc
     3481 gtataggttg ctgaggttga aatagctttc tgccttatca atacctgagt cgcttaggcc
     3541 aatcgtcttg gtcggaacat caatgatgta atccactgaa tccaaggtct tgacaaacat
     3601 gtctgcacga atatagagct gattcgtttc tgagctcaca gcaccagata caatcagagg
     3661 tgttcttgcc tcgtcaatca aaacagagtc aacctcatcg accaaggcaa agttcagtgg
     3721 tcgctgaacc atgtcctctt gacgaaccac catattatca cgcaggtagt caaagcctac
     3781 ctcagagttg gttgagtagg taatatcaca tagataagcc tcacgctttt cagctggtga
     3841 tttggctgct aggttgatac cgactgaaag ccctagccag ctatacacct ctcccatctc
     3901 tgtcgcgtca cgagttgaca agtattcatt aacagtgata acgtgtaccc cttcgccagc
     3961 aagggcatta aggtaaacag gcatggtcgc tgtaagggtc ttaccttcac cggtacgcat
     4021 ctcagggaca tctccattgt gcaagacaac cccccccatg atctgaacac gataagggta
     4081 aagtcccagc acacgtctag ccgcctcgcg gacaaccgca aatgcttctg gtaataactg
     4141 ctcaagggtt tccccatttt gataacgttg tttaaattcg ggcgtttttg cttgtaggtc
     4201 tttatctgac aaggactcca tatagtcagc ataggactct acttttttcg caattttttc
     4261 taattttcgt aattcgcctt tatcattttc aatgactttg cgtagaatat tgctcattct
     4321 ctttcctttc gatcgactaa tcattttatt ctaacataaa taggcaggca gttcaagaaa
     4381 tgatcataag atatccatga cagacgcatg aagaaaatca tttattgaaa aagttgtgaa
     4441 aatagcaaaa tagccatttt agggtatttg acagagtgtt tcctgaattg ttatattctc
     4501 cctctataaa cttttcttga aaaatttctt ttctgcaact atcgctatgg ctttcctatt
     4561 tttcagaata agttttcgca ttcagaaata tcttggaaat tttttcttca tgcgtctgtc
     4621 gtgataagat atcagaaaaa gaaaggccgc ttgtccaaac agtctttctt ggtgttttcg
     4681 tgtattctgt acttaattag gatgactgac aatcatttcc agctgaccat caaagctcca
     4741 tgacgtcaca tcatttggca ggataaaatg catacccttt tgaagctcgt aaacagcttg
     4801 atcaatcgta aggcttccct gaccagctag cacactgaca agcaggtaag gggctgattg
     4861 cttcatgctg actgcttgat caatctccca tttgtaaact gtaaagaagg gattagatac
     4921 taagcaggta gagaccaagt gctcaagttc tagtgtggct ggcgtgctgt tctcaggctt
     4981 gccaatagtt aggacatcga tagatttctc aatatggagc tcacgaagct gaccttcagc
     5041 gtctcgacga tcaaaatcat aaacgcgata ggtcgtgtct gaggattgct gcgtctctaa
     5101 gatcaaaatt cccttaccaa tggcatgcat cgtgccgctt ggaacataga agaaatcacc
     5161 agccttaacc ggaactcgcg tcaacaactc ttcccagttc cccgcctcaa tcatcgcacg
     5221 aagctcttgt ttagagcttg catgatgacc ataaacaatc tcagcgcctt cttcagctga
     5281 aataatatac cagcattccg tctttcctag ctctccctca tgggccagcc cataagcatc
     5341 atctgggtgt acctgaacgc ttagccagtc attagcatct aaaatcttcg tcaacagcgg
     5401 aaagaccttt tcctttggat ttccaaatag ctctggtctt tctgcataaa gctgatctag
     5461 cctttggcct tggtagctac cactgctaac tgtggaaaca ccattagggt gagctgagat
     5521 tgcccaatac tccccagtgg tttcggttgg aagctcatac ccaaacacct ctcttagctt
     5581 tgttccgccc cagatcttat catgcatgca tgatgttaaa aataatggtt ctgacatagt
     5641 aatcctcatt ctcttttcac taacctatgg tgacattctt tgccccaatt ctaccaattt
     5701 caggcacatt ttgcaaatga ctctaggact tttatcaaat aggctcaagt atctagctct
     5761 tttcagcaat cagctttgct aaagcaaaat tcccaagagt ggccgagcca ttacctgcaa
     5821 ctgctggtgt gaccaaatat tctctaacat cagctactgg taaataacca ttaatcagtc
     5881 tggtaaaggc ctcctgaaca cgcaccagca tgtgctcctg tgccatcaca cctccaccaa
     5941 acacaataac ctgaggacga taaagcagcg ttgcctgtac agcagcctga gctatataga
     6001 aggcttgaat atcccaaaca gcggccttct gatcaagaag ctccccctta atccctgccc
     6061 ttgcttcaag gcttggccct gctgccatgc cctctaagca cccccgatga aatggacaaa
     6121 cacccaaaaa tgcattcgcc acatcgtcaa ggtgctgcat aacataggta tgtcccgcct
     6181 ctgtatgacc taacccaccg ataaactcac ctttttgaat agctccagca ccaatacctg
     6241 ttccaatcgt ataataaaca agactgtcaa catcaggtcg agagatagcc tccccatagg
     6301 cagaactatt aacatcagtc gtcacataaa aaggaatcgc aaaggctgct gtcagctgcc
     6361 ctaatagatc tacatttgcc caacctggct tgggtgttgt ggtaatgtag ccataggtag
     6421 ctgacttagg atcaatatca atcggtccaa aggagccaat agcaatacta gccaagtcgg
     6481 cctcaaattg cttaaaataa gcaatcgtac gctcaatagt ctcttttgga cttgtcgttg
     6541 gaaattgcac cttatccaca acagcaaaat ccctatcacc aacagcacag acaaactttg
     6601 tcccgcctgc ttcaatactt ccaagtaatg ttttcatctt ttctccttaa taatagtgat
     6661 aagccctgtg ctggttattc tcacaaggct caaaatccca ccagctaatc agcagctacc
     6721 ttagtagcta aacatcatcg cttgcttcct tgcctcctag aaaagaccaa aaatctggga
     6781 taggactatc tcagattttt gatatgcctt taagagataa ggcaattgat tttaggaggg
     6841 aaaccttggc agcaggagct gccaccaaga agcagcacaa acaattgctt ttaatggtgt
     6901 gttcatcgcc ttatctctaa agcttaatgt gttagcgtaa tgatcagtaa cctcaagcta
     6961 acggccaaga acgacagcct gctcaaggat aagctagtct gtctttggat tttctggctc
     7021 agtattttct tttatgtcag tagccacagg ctgctcaact ttagctgctt tagctacttt
     7081 ttcctgatca gttctatcag ctaaaagctt atcaacataa gccttcagat cagcagtact
     7141 agcgttaata gcatcggcat taaacatctt actatctaaa gcagccttta aggcagctat
     7201 tttgacttcg agctccttaa gctgctcttg agagaacttg tctttttgct gagatagctc
     7261 ctctgcagta gctagcattg ccatcacaag atccgcagcc ggtaattgat aaccaatgat
     7321 ttgaagctca ggaagtgatg gccaattgta acgtcctccc ttagtatcaa ctgttattct
     7381 ccaatatttg gcaccaatgt tgtttaacgg ctggctaaac tcttggtcct ctcctgaata
     7441 atctgaaact gttacccatt ttgatgattt ttccaagcta tcctttacct ttgagccagc
     7501 ttcaagatgg ccaacaaagg cttcaagctt ggcctcctta atacagtcag ctttactaat
     7561 tttgctgtca ttaaagaaac gccaatactt gactaagcca ggctctttaa gttcaaaaat
     7621 gatagaagct ttattgctag ttgacagaat tgttgtatca ttattgagca aaccatcaaa
     7681 cacttttttt gcatttgttg gatctgcatc accaccaatc acagttgctc cctctgctag
     7741 gttaaccatc atggtttttt ccgcaccaac gacaacctta gcctcatgca caggcttagt
     7801 gctattagta gggctaaaga attcaacctt gtaggtctcc tccttgctag tggataagtc
     7861 cttgtgatca gtgacaccta aggttgagtc agtcaccttg atcttatagt ccttgtaggt
     7921 cactgcaaag gctttgtaat catagcttga atcaacaaaa cggtgacctg ctatttcctg
     7981 ctcctgataa gccttatagt cagcttcgct attgattagc gtgccctgat tggtaactgt
     8041 tccaaataaa agcttagcct gcaaatcaat tgtatcattt gctactggta actgaaggct
     8101 cttagtgcca taagtatcag gataaagacc agtaggcttt tgatgatcaa atacaaacgt
     8161 cttttcgcta acaccgccat gcttagtcac tgttgccagc atggtatcaa gaatctgacg
     8221 attttccgta ccagctgcta agtccagctt attactagag agatccacct tttcaagaga
     8281 ggttaggcta gctgcgtcaa ttccagccaa gctatcacga tcaaagccag caagatttaa
     8341 ttccttcaag ccagttagac cagaaatggt cagagccacc tgtggaatcg ccttagtctc
     8401 ttccttctta gcgctgccgt aggcttcaag aacattggcc agcgtatcct tggtcggctt
     8461 agcatttgca ggtaggacta agctatccag ctttgtgatt tgtgatagac cgattagctc
     8521 tagcttagct agttttttaa gcttattcag gccttctaaa ctcttgatat ccggattgtc
     8581 taagcgcagg gttccattga accgctctaa atcccctctt ctgcttccaa cctgtgcaat
     8641 aactgcttct cgcaaagcct tgtctggaaa atctttctga tcaatcagct cataggattt
     8701 gtcattttcc ataaccttct tcaaggcctt agaaacctta taatctgatt tgacaatacc
     8761 atctgttata tcctttatag ccttgttagt tcttttctca tcatctgaga cttttttagg
     8821 ttgatgcgct acaccatcgc gatcaatcgc ataagagaaa atccctccct tgacaccacc
     8881 tgtcttaggc tgccattttg cataacgctc agcacgagta ccagctatct ctgaatttaa
     8941 cggattatga tcatctttcc tctcattaat atcataccag aggttaccac tgcccgcatt
     9001 ttcctcatag aaagaaaaac caaccatgta ctgctcagga cgaatgtatt tgctatacga
     9061 ttcccaacgt tcctccattg tcttttcagg ttttctagcg actggatccc aatctccctt
     9121 ctcaccttga gtgccataaa cctgcacaag cagcaaatca atatattggg caccgcgctc
     9181 aatcaatggg ttcttgtcag ccatgtaggt gctatccata atgaacaaac gtgacttgtc
     9241 agcgcccttt ggcccaataa gcttgccaat ttcttcaaaa acagcaatag agcgctgaat
     9301 attttcgtta ctctcttttc catttacttt tggaatgcta tcccgctcaa tatcaacatc
     9361 taaaccatca agattatatt tataaacgta ttcatctaca atagcctttg ccaaggcctt
     9421 atttccctct ggagtatttg ggtatttttg cgtatcttca gcaataccac tatgatcacc
     9481 gcctgcaagg aaccgccatg gaatggtacg aatcacacgt gttccctgct tgttcagcgt
     9541 tggcacatgc ttggtcgcca attcttgcca gaaaaagcta taatccttgg tccaatcatg
     9601 gaaaacaaag gctaagtcaa cctccttagg caattctccc atagaattaa ccttatcctt
     9661 ttcagccgga tctgatgttt tatcatgcca agtcctaaaa tagccaccat aaagaggccc
     9721 ctttaaaggc ttcatggcta ttttttcagg aaccttcatt tctgcaagaa cctttgcctg
     9781 cttatctgcc tgctgtgcct tggataaaat atcctttagc ttttcaggta cttctcctgc
     9841 ctttgataac ccctccttaa attctttttt actgttttcc gacaggtaat gtaggtcatc
     9901 aatagcagag actgatggac tagtttgcac aaccttatcc tctgccttga cccttatgag
     9961 tgaatcatgt tgggcagcta atatagccac cattaacgct gcagcacaaa cacatttcag
    10021 tgttttcttg actaacacct gtttttccat tgggacactc ctttattttg ataccaaaga
    10081 atggcaaatc tttgctgaac caaaaatgta agcgcattct ctgcgttcgt ctaaagtata
    10141 gtagacctca tgatcaaaag caatgcacaa agtataggta aaataaaaga aacttaaggt
    10201 cttttaattt ctgtaatttt atggtgaata ttttaatctt acatgtaaaa agagatgaaa
    10261 tcatcaactc ttttcaaatt attttacaag gatcactgga ctgccaacag tcaccttacc
    10321 ttgtgccaaa atctgaacag catgaacatc tgcgctattg gtgacaagca gcatggttgt
    10381 agtatcaagg cccgcctgct gaatccttgc aatatcaaag cttccaagag catcaccagc
    10441 cttgaccatc tgaccaacct taacaaaggt ttcaaagccc tcacctgcca ttgaaacggt
    10501 atcaatacca atatgcagta ggatttctgc tcccttatct gatttgatga cgtaagcatg
    10561 acctgtctca agggcagcct ctaccctgcc atctaccggt gagcagagaa tgcgcccttc
    10621 aggcttgatg gcaacgcctt ggcccatgct tcctgacgaa aagacaggat cagcaaccga
    10681 tgacaaatca atcaactccc ctgcaactgg actaagcagc tcctcagcag cagaggcttt
    10741 ttgcgcaggc tctgatttta cttgggtagc cggtgcttct tggtcactct tgtccttgaa
    10801 tccccaaata taggcaatca caaaagctag accaagccca accaacagtg tcacaaggta
    10861 ctgtagtagc tgaccattaa gatacagcag tgcaccaggc aaaaccgtaa tcccaaagcc
    10921 ggtaccagca atgccaagaa tccctgcaac ccagccacca gctgcgcccc cgataagtcc
    10981 tgagacaaat acctttgggt agcggagatt aaccccaaag atagccggct cagtaatccc
    11041 taaaagagct gacagagctg atggaaaggc taaacccttt aattttgcag acttggtttt
    11101 aacagcaacc gctagagttg ctcctgcttg ggcggccgta gcagctgtca aataagcgtt
    11161 aaagggatcc tttcctgtat tggcaactag ctgcgcctcc aagaaattga aaatatgatg
    11221 gatacctgtc acaacaatca gctgctgaac acccccaata acaaggccgg caatcccaaa
    11281 aggcagacct aaaactgctt gtgtccctgc aagaacaagg ttttccaagg agtgaaagat
    11341 aggcccaatc acaaagagcc ccaaggcact cataatagca aaggtcaaaa acggcgttgc
    11401 caacaaatca agcgcatcag gcacccgctt atgcagccac ttttccagct tggcaccaac
    11461 cagaccaaca aagaaggctg gcaataccgt accttgataa ccaacaactg gaacaaaacc
    11521 aaagaaagtt aagggcttaa catcacctcc tgaggctacc acccaagcat ttggcaactc
    11581 attagagacg agcatcaagc caaggacaat cccaatgata gggttgccac caaataccct
    11641 aaaggctgac caagcaacca aggccggcag gtagacaaag gccgtatctg ttaaaatccg
    11701 agtgtacatg aggaaattgt cgccatagtc atgaatacca aagaactcca taacagccgg
    11761 ctgcgtcaag agaccccgta cacccataaa cagccctatc gccacaatag caggaatgat
    11821 cggaacaaag acatcaccaa aggtacgaat agcccgctga aaggcatttc cagacttgac
    11881 cacttgctcc ttttgctcac ctgccaaagc agctggaagc cctagagcta caacctcatc
    11941 ataaatgcta ttaaccgtac ctgtcccaaa aatcagctga tattggcctg agttgaaaaa
    12001 agcaccctta accttatcaa tagcctctgc tttttcctta ttgatcttac cctcgtcatg
    12061 aaccataacc cgcagccgcg tcgcacaatg agccacactt ctgacatttt cacgaccgcc
    12121 taaggcctcg ataacctctt ttgcaatctg atgattatcc ataccgatag catctccttt
    12181 tttgtctgtt atagtctatc gaaatagctt ttcttgagcc tatccaatat tggcggacct
    12241 accctactgt ccgactcaag atggtctttc aatttactat tgtgaatccg cttcacttct
    12301 tgctatcatt ttaacacgaa tattttttat gtcaagcgtt tgacatatat tttgtttaaa
    12361 ataattaaaa aagttgattt ttagagagaa aacgtttatc atatgaataa aaatgaccaa
    12421 tacctaagga gacctgacat ggatttacca agatctattc gctaccgacc atatcaagaa
    12481 tggagcaagg aagcctatca agcaatccaa caaaaggtgg cccagtcttt atggcgcagc
    12541 catttccata tagaagctcg tacaggtctc ctcaatgacc caaatggctt ttcttatttt
    12601 gctggcagct ttcagctttt ctatcaaaat tggccctttg gagcagctca tggtctaaag
    12661 caatgggtac acaccacatc aactgacttg gtgcatttta cagaaaccaa aactcggttg
    12721 ctgccggatc atcaaaacga tagtcatggc gcttattccg gctctgctta tcctattggt
    12781 gacaaactct ttttatgcta tacaggaaat gtccgcagca aggattgggt acgccaccca
    12841 ctacaaatag gtgcctggat ggaccaatca ggccacatca caaaatgtga gcaggtgctc
    12901 attgacaagc cagatgatgt cacagagcat tttcgtgacc cccagctctt tacctaccaa
    12961 gatcagcttt atgccatcat tggtgcacag aatttgcaac aacaaggtat cattaagctc
    13021 tacaaggcta acaacaatga tgtcaccagc tggcaatttg ttgctgactt ggattttgat
    13081 gactcaggca ccgcatacat gattgaatgc cctaatttgg ttttcattga agataagcct
    13141 gtgcttatct tctgccctca ggggcttgcc aaatcagagc ttgattacca aaacatttat
    13201 cccaatacct ataaggtatt tcagaccttt gatcctaaaa gacgcaagct ccttggggga
    13261 ggtccaatcc aaaaccttga ttttggattt gaagcttatg cgacacaggc ctttaatagc
    13321 cctgatggta gggtactggc agtttcttgg attggcctgc cggacatcga ctacccaacc
    13381 gataaatatg cctaccaggg agcgcttagt ctagtcaagg aattacgact caaaaatgga
    13441 aggctacacc aagcaccagt ccctgctctc agtaagctac gagacaaagc ccagcccttt
    13501 cagaacaaaa aaaacagctc aaactgctat gagctggctt tgaccattga agcacagcaa
    13561 gcaacagagc ttttgctctt tgccgataca cagcacaagg ggctgaaact gaccgttgac
    13621 acctgcaaag gacagctaac aattgatcgc agcaaggcag gcgcccagta tgcccaggaa
    13681 tttggagcaa agcggtcttg ccaaattcct gtcaatcgtg ctacacttaa tatctacgta
    13741 gacaagtcta ttctagagat ttttgtcaac caaggcgaag cagtcctcac gagtcgtgtc
    13801 tttccaaatg aggggcagtc tggcattgag ctgctaaagg gccaggtgag tggctactat
    13861 tatgaaatga ggtactagac aagtggtcgc aaaattaaca gatgttgcag cattagctgg
    13921 tgttagccca acaacagtct cacgtgtgat taacaaaaaa ggctatctgt cccagaaaac
    13981 cattgataag gtgaacaaag ccatgcgaga gcttggctac aagccaaata acctcgcacg
    14041 aagcctgcag ggcaaatccc ctcagctcat tgggctgatc tttcctaaca ttagtaatat
    14101 tttttacgcg gaattgattg agcatttaga aatcgagctc tttaagcaag gttataaagc
    14161 catcatttgc aacagtgaaa acaacccgat caaagaacga gattatttag aaatgctagc
    14221 tgccaatcag gttgacggca ttatctcatc aagccataac ctaggtattg atgattatga
    14281 gcgtgtcgag gcacccatcg tcgcctttga tagaaacctc gctcctcata tccccatcat
    14341 atcctctgat aattttgaag gagggaaatt ggccgcaaaa accctgcaaa agcatggctg
    14401 ccaaaaaatg atcatgatta caggaaatga tcattctgac tccccaacag gtcttagaca
    14461 gctaggcttt aattaccagc tcaaaaaagg cgctgatatt ataaaactgc caaatgatct
    14521 ttccagtatt cgccgcgaaa tggaaatcaa gtctattttg gcgacaagaa ggcctgacgg
    14581 catttttgct tctgatgatt tgacagctat cctcatcatg aaggttgctg gccagcttgg
    14641 catagcaatt ccagataacc tgaagcttat cggctatgac ggtacggctt ttattgagca
    14701 ttatttccca cagctcacca ccatcaagca gccgatcaag gagattgcca gcttaaccgt
    14761 agaagtatta ctgaaaaaaa taggtaacga aaaaaccagc aaggactatg tcttaccgat
    14821 caccctgctt cccggaggca gtctctaaga gcaatagctc ttcttctgtg attagcggct
    14881 ttcccctagc ttctccctta cttggggcac taaagtaaaa accaaagcac gaggtgggaa
    14941 accctagacc accaggatac acccagatag gtccccaaaa gaaagcttga taagcctgac
    15001 cacctaacaa aacctgcaca caaggaaagc ttcctcaagc tgtcctttgt acccttttcc
    15061 taacaatgcc accaaaaaca catgtaacag caagtgacag actcccccta tagcaaacag
    15121 tgacccaaca aaccatcact agaagctata aggggagctt ttctatgcct aacaaaaatc
    15181 taaaatcaat aacagaaaaa cctaaagcag ttcatgcgca catactacct atctgctact
    15241 attgctctaa aagcaaccgg ctgatcggac aggttggtaa tggtgatact atagtcatga
    15301 tcttctgtca cactatattt tctcttcccc ttcaagggaa cgatgaggcc atctccatca
    15361 atagtagctc ccttgtgtcc agcttctaca ataactacac cattatcctt agtggaatcg
    15421 tatttttcaa taacctgttc tgttatagaa taccgatatc ctatcttact aagatagctg
    15481 tctgtccgtc tataaatata ttcagaccat atatcacgac cttctagctt cagtagcact
    15541 ttttcgtcgc tttctaggta taggtcagag gaatattcta tttgttcata ctttggtctc
    15601 accgcaagct ctatactctc atttggcctt agatattctt ttccttgaaa aaaatagtaa
    15661 agctcatagc gtttggagaa gatgaaaaca cctaccagca acatcattaa taacaggatt
    15721 tttcgcttca ttttgacttc ttccttttca tataaccatc tatacctgct tggatcattt
    15781 gagtatcacc ctcattgtct ccatagtgac ctgatgataa gttctttaac cactttggta
    15841 tatccttatc agaaaagacc tgggcaatct cagccgccgt ttttaaataa gtccctgaag
    15901 catctaaaaa gcctgtacca acataaccat agaggtagtt gccagcatag tcgcctggca
    15961 attctgattc ccactgtctt gaccagacag aatagttatg gccatgatag gtccttgact
    16021 tcaaatccaa gggctgaccc gtattgacaa ggtcataaaa ttgtttgttg tcaagtattg
    16081 cagcacttaa ttgacttcca gctacctgtg aaaggtaggg agcattgaca ttcactgata
    16141 ggatatcatc tcccatcttg ttgacaatca aacgaaaatt aatacccgac gattgtaatt
    16201 ttttccctag gtcttcctca atttcctttg catatttatt atttttaagg tctcactctc
    16261 catcataatt gcttctcgcc ttccaatagt catcaaaggc tgttttattg agaaaataga
    16321 ggtaatcctc ataggcagct acaagtcgct ctgatttttg tagtggcctt tcagagctgc
    16381 ttttgatggt tttaatggtc tgagtcagta tgttgtgata atggttttga gtgtactttg
    16441 aggcattgac agggctaatc ttttgattct tcaggctagt cacccagctc atatctaggc
    16501 cagcagtcga gtagctgccg tcgctgctca tgaagacctg actgagctgt gttgcgccct
    16561 gaatggctaa ccgcaaaata actaagctgt ccctaaagca gtctgaggtt tgagttagaa
    16621 accattcaag gctttccaat ttggtcgtaa catctcgaat ccctatttcc agctggtttt
    16681 tggcatggta tagtgtagag gtatcagacc aaagggtgcc atagtctccg gttaaaagac
    16741 tactgacctg cttcataaac gattcgtttt catcaatctg tgcttggatc acttgcactt
    16801 gccgttctct tagcctcttc agctcggtta agtgatcacg atccagggtt ccgtatctgg
    16861 caatctgagc atctgccctt tgataggtgg tcaactccac ttggatagca tcaatcgctg
    16921 cttgtagctt tttgatagag ggaatgatga tcgctgtaaa aagtccccta cctgctgtat
    16981 aggctgctcc ctgtagctct cccgaatcca gactagcaat gagatggtcg caaccacttg
    17041 ataacctgtc cgttatttca ttggctattt ggatattgtt tgtcatggct tgaatcaagg
    17101 cctttgactc tgctgcactg taggtcactc ccatcgtaaa cggctccttt caccgataag
    17161 ctcttctttg tccctctcta gtctacgacg aacccccatc gtatagattg acacgtgatc
    17221 cagatgctca tcaacatagc gatccatttg tctgatcaag tggtcattgg cctcttgctc
    17281 tgcgtacttt ccagcttagt cctcaggcat atggttcaat agggactcaa gggcaaaaga
    17341 gaggtgctga cagtctgctt gaatctccga gactgcttgt tcatgccgtc gtttcatcga
    17401 caaaagatcc tcctctagcc actccagctc attgatctgt cgggttaggg caagaaattt
    17461 ttcttcagat tcttctttga tcatgactta ttcccctatc ttgttgcttc ctctaggtct
    17521 cttttctcta atttggccgc aagctgagga aatttattag cctgaataag gactgcctga
    17581 ctaaagtcgc tgacagcctg cagcagttga ttagagacct gacgtccctt ttccatacct
    17641 gcaataccct tggtcacact aaatgcaacg gactgttggt gaaccctact ggtgtctaca
    17701 cctaccaatt cactaatagc agcagaagca gccacagggc ttgatgtaat ggtatcactc
    17761 atacaatttc tcctttataa cccttatgtc ttttattata tcacaggata atagccattg
    17821 tgcttatagc tcttacctaa ataatagcaa ctgat
//
LOCUS       DARYYD010000039        17665 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.039, whole genome shotgun sequence.
ACCESSION   DARYYD010000039 DARYYD010000000
VERSION     DARYYD010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17665
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.039"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..918)
                     /locus_tag="TV188_001376"
     CDS             complement(<1..918)
                     /locus_tag="TV188_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEL1534723.1"
                     /translation="MSKKLLKREITDAVDFLLDDGNALEQGNIQNIELDLLENYHNHP
                     FTLYTGKRLDDMVESIKENGVLNPIIVLKKDNNYEILSGHNRVNAARITKIKSIPCIV
                     KENLTDKEAYTYVIETNLIQRSFSDLLPTEKALVLKMRYEKIASQGKRNDLQKEINNL
                     DQGIIEKESKEEDKIDSRKTLGKEYNLSGASIARYLRLNELSKSWKKDVDEDKIGLTM
                     AVDLSYLSKEIQEYLYQKCEELELSLKPSDAKALHLMNRQEDLNQEMVITYLLNLKKT
                     KVKKYQNIKLSQSVYKKFFHDERKEDVEEI"
     gene            complement(911..1687)
                     /locus_tag="TV188_001377"
     CDS             complement(911..1687)
                     /locus_tag="TV188_001377"
                     /inference="COORDINATES: protein motif:HMM:NF022077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL1534724.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIKKYAKGSSVDIAYDNLAKEICYE"
     gene            complement(1839..3002)
                     /locus_tag="TV188_001378"
                     /pseudo
     CDS             complement(1839..3002)
                     /locus_tag="TV188_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(3004..4725)
                     /locus_tag="TV188_001379"
     CDS             complement(3004..4725)
                     /locus_tag="TV188_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534725.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            5174..7180
                     /locus_tag="TV188_001380"
     CDS             5174..7180
                     /locus_tag="TV188_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL1534726.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            complement(7371..7781)
                     /locus_tag="TV188_001381"
     CDS             complement(7371..7781)
                     /locus_tag="TV188_001381"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1534727.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(7913..9262)
                     /gene="gdhA"
                     /locus_tag="TV188_001382"
     CDS             complement(7913..9262)
                     /gene="gdhA"
                     /locus_tag="TV188_001382"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL1534728.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            complement(9403..11179)
                     /locus_tag="TV188_001383"
                     /pseudo
     CDS             complement(9403..11179)
                     /locus_tag="TV188_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(11179..12924)
                     /locus_tag="TV188_001384"
     CDS             complement(11179..12924)
                     /locus_tag="TV188_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534729.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISIPKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            complement(13029..14896)
                     /locus_tag="TV188_001385"
                     /pseudo
     CDS             complement(13029..14896)
                     /locus_tag="TV188_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            complement(14889..16100)
                     /locus_tag="TV188_001386"
     CDS             complement(14889..16100)
                     /locus_tag="TV188_001386"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL1534730.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            complement(16200..17048)
                     /locus_tag="TV188_001387"
     CDS             complement(16200..17048)
                     /locus_tag="TV188_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1534731.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            complement(17048..17428)
                     /locus_tag="TV188_001388"
     CDS             complement(17048..17428)
                     /locus_tag="TV188_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL1534732.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
BASE COUNT         5193 a         4133 c         3170 g         5169 t
ORIGIN      
        1 aatttcttct acatcttctt tcctttcatc atgaaaaaac tttttataga cactctgaga
       61 tagtttgata ttctgatact tttttacctt cgtttttttc aagttcagca agtatgttat
      121 aaccatctct tgattcagat cttcttgtct gttcatcaga tggagtgctt tggcatcgct
      181 tggttttaaa cttagttcca attcttcgca cttctgatac agatattcct gtatttcttt
      241 ggaaagatag gataaatcta ctgccatcgt caaacctatt ttatcttcat ccacatcttt
      301 tttccaagac ttagataatt catttaatct taggtacctt gcaatagatg cccctgaaag
      361 attatattct tttccaagtg tttttctgct gtctatttta tcttcctctt tactttcctt
      421 ttctataatt ccctgatcta aattgtttat ctccttttgc aaatcatttc tcttgccctg
      481 acttgctatt ttttcatatc tcattttaag aacaagggct ttttccgtcg gcagtaaatc
      541 ggagaaagaa cgctgtataa ggtttgtttc aattacatag gtataggctt ctttatccgt
      601 tagattttct ttaacaatac aaggaatact ttttattttt gtaattcttg ctgcatttac
      661 tctattgtgt ccggaaagta tttcatagtt gttatctttt ttcaagacga taattggatt
      721 aagaactccg ttttccttaa tgctctctac catatcgtct aatctcttac ctgtatataa
      781 agtaaacgga tgattatgat aattttcaag caaatcaagt tctatattct gtatatttcc
      841 ttgttccaag gcatttccat catcaagcaa aaaatctacg gcatcggtga tttctctctt
      901 tagaagtttt ttactcatag cagatctcct ttgccagatt gtcataggca atgtctacac
      961 tactgccttt tgcatatttt tttatgcttt gcccgctata gatggcttcc ccaactttaa
     1021 ctgttttcgg aattttggtt tgaaagacct tgattttctt ttggaacatt tcttctactt
     1081 gctccatcag tgttttggac agattggttc tattctcaca catggttagt aaaatcccct
     1141 gcactttcag tttcggattc actctctttt ttattttttg aacagttttt aaaagttcat
     1201 tgattccaac aactgcgaac agctgtgtat ccgctactat aaggacactg tctgaggcac
     1261 aaagagcatt tatagtcaaa acactaagtg atggtgatgt atctatgaga atatagtcat
     1321 aattctcttt taccctccta ataatttccg ataatatacg ttcacttcct gtttctgctc
     1381 tcatttgtgt ttcaacggcg gataagaaaa tgcttgaggg gataatatct atctcatcat
     1441 aagatttggt atagccctct accaaatagc tttcttcttc ctccagttct accattaaca
     1501 aatgccctat ggtttttata ttttctgtat ttcccatatc aaaacatctt gtaagattag
     1561 cttgtggatc aaggtcaatg actaatactt ttttccccag ttcttttagt gaataggcaa
     1621 ggtttagagt tgtagttgtt tttccaactc cgccttttcg attggctatg gttatcactt
     1681 ctgccataaa gtccctcctt cttctctata cagagatttc attttatgct atacttttat
     1741 ataattttag atataaaaaa agatgatagc ctcaatccat catcaagttt aaaagttttg
     1801 cggaagcctt taaccattga ttttacttgg atttattgta ctatcatcat tatagcattg
     1861 tccccagagc cagtatgccc tactagggca accgtctccc ctttatcagc atgaatggta
     1921 atatcagata aaactgtctt gccattttcg taagcaaaat acaccttggt aaaatccaca
     1981 gtaccatctg ttagctcaat tgctcgtgct ttatccggct ctgtctgcgc ctcaagcagc
     2041 ttcattaggc gcgttcctgt cgctgttgag cgctgaatat taggtagctg cctaaccagc
     2101 atacttaata aatcaaacaa gcgcagcaaa taattgacgt aaataaagag cttaccaact
     2161 gtgatgcctg atctcccctg caagaactgg taaccaataa cagccaaaat agcggcaatc
     2221 atgccatact ttaccaattc cgtcagggtc catgaagcaa ctgactctgc aaaaataatc
     2281 ctatcatcag ctgttttcat ctggtggatc tgctcttcaa attcctctaa gatcgtatcc
     2341 tcttgatgat aaagctgaat aatagaaaca ccattcatgg tttcgttgac ttgtgtgttg
     2401 acagcgctcc tagcctgata aaaatccttc attggctggt cagtcaagct tttatacagc
     2461 cattgcatgc cataaaagag tggcataata agcagcaaca gcaagcctga cttcacatca
     2521 aggtaaatca tcaccacata aataaaaata atttgtgaaa gactgacaat aatttgagac
     2581 aaaaggttat cataaaattg attcttcagg gtttcagtat cattaacaat cctagttgca
     2641 atctttcctg caggctgatg atcaaaataa gctatcggca gcctctgcat gacatcaaag
     2701 gctcgattac gaagattagc aacgatccta ttagaggaat aaaccagcat tcgataagag
     2761 atataacgca aaactgctgt tatcacaatt aacagcaaat acagcaggag caagcgctga
     2821 aagccttcaa tcggtacctc ttttcctcta gctatcggag tcaagtaatg atcaatcgtt
     2881 tgttgcaaca ataagggagc catctgacct ccagctgttg ccactagcaa aaagcctatt
     2941 gccagggaaa aagccaaggt cacagcttta atttctttta ttaattttat aaatagggtc
     3001 atcttaaacc tcctgagcct gctgacgctg gtactgttca taataccagc ccttctgagc
     3061 taaaagttgt tggggctgac cttcctctac tatctgcccc tgatccagaa caataaccca
     3121 atcggcatgc tgaatcgcag acaagcgatg gctaacaata agtgttgtct ttccctttct
     3181 ttcgtcttga atgtgtcgaa taatatcagt ctctgttcta gcatcaactg ccgacaggga
     3241 atcatctaaa atcagcaaat ctggctggga caaaaaggct ctggcaatcg aaatacgctg
     3301 cttttgacct cctgaaatag acagaccacg ctctccaatc tcagtatcca agccctttgc
     3361 cattccttga acatcacgcg taaaggccgc agtttcaatc gcctccaaga tttcctcagt
     3421 tgtagctgcc tttttcccca tcgcaatgtt ttgagcaacc gtttttgaaa acaggatatg
     3481 ctcctgtggc acatagccaa tttgacgctc aagtgattga cgcttataat ccaagacact
     3541 acgatgatta atcatcagct gcccctgccc aagagggtat tgtctcaaaa actgcctgac
     3601 aagggttgtt ttaccagagc ctgttttacc aacaatccct aaggtttgtc cctttttcag
     3661 ggttaaattg atcttttcta agctaggcct agaactattg gcataggtaa agctatagtc
     3721 tataaaagca atctgatcaa agctctctaa ctcaagctgg ccatcaggct ccatatcatc
     3781 acttgtttcg atgagttcat taatcttacc aaaagaggtc tttcctgtct gataaaccaa
     3841 aataaagtct gacagcatgc caaagggctc caccaaagac accagataaa gctgcagcgc
     3901 aatgacttga ccaagtgtta cctctgagct tgctatgagc tgtaggccta ccattaaaat
     3961 gattactgta ctaatggcaa tcatgacgct gtaaagagga aagtacaagg cacgatactt
     4021 ggccacctga ttccatttat ctgccaaatt ctgagtcttt tgagcaaaat gaagtgccaa
     4081 ataatctttt ttactgtaag cacgcatcac tctaatgccc tcaacggttt ctagtacctc
     4141 atcactaagg cttgaaatcg cctcacgcgc ctcttcaacc aaatgctctt gctttttcgt
     4201 cacaccatag atcatcacca tcataagcaa aatcggtact attcctatca aggtcatttt
     4261 ccaagaaatc aaaaacatgg tcggaataat aaaagcaatc ataccaccag catataggat
     4321 aatcatcaag ccatagccga taaggtccat aagtgcttcg acatctgttg aaaaacgcgt
     4381 gatcatgtca cctgagcgaa atttctcata aaaaggcgtt ctcataaaaa caagctttcg
     4441 aaaggcacgc tgctgaatat caaacttaaa atgaactgcc tcctgaaata aatgaagatg
     4501 ccacaaataa gcaaccccat aagacactac tgccgtagcc aaaagaatga taacatgcct
     4561 caccaatgcc cctgagctta gctgatgcct tgacatcaaa tcaaccaagt cttgaataac
     4621 ccttgttggt atcacaagtg aggcatcata tatcactaaa gtcattgcaa taaggatata
     4681 aatccatttc ttttgcttaa tatgttgaac aattaaggtc agcatcatat cctccatttc
     4741 tgaactaacc tatttcaagc tgtcttaaaa taggattttt gcacacaaaa agcccgcaat
     4801 aagatatcct tcctaccgcg ggctctacta tttctattta gtgaaactaa aagaaactaa
     4861 ctgttttggt tagaaaggag actatcgtaa taatggttaa atagttgaat gaaacggatc
     4921 attattaatt tctcctttct tttaatctgc ctaacatctt atcatagaat actgggcttg
     4981 taaagccttt tttggatagt tcttctattt ttttacaaaa aacgcttcca atgtttgcat
     5041 tttaaacgtt ttcagtgatt agcaaacgct atcgttgaat ttttgttagc ttttttatta
     5101 atttttgttg aattctcatt taaataatag tacacttaac ttgtgacaat actttaaact
     5161 tttaggagcg tttatgaaaa agcattttgt tttaaaaagt agtgttcttg gtgtctttgc
     5221 cggagtttct atgctagtaa ccggcgtgca ggccgatcag gtagacgtgc aatttcttgg
     5281 tgtcaatgac tttcatggtg ccttagacac aaccggctct gcctacatgc cagaaggaaa
     5341 ggtatctaac gctggtaccg cagcacaatt agctgcttat ctggacgatg cagaggctga
     5401 ctttaagcaa acaagcccag atgggacaag cattcgtgtt caaccaggag atatggtcgg
     5461 agctagtcct gctaattctg gactattaca ggacgagcca acggttaagg tattcaacca
     5521 gatgggcttt gaatacggaa cccttgggaa tcacgaattc gatgagggct tagctgaatt
     5581 caaccgtatc atgacaggca ctgcacctgc tgaagactca gctatcaacg acattactaa
     5641 gcaatacgag catgaagctt caaatcaaac ccttgtcatt gcaaatgtcg ttgacaagga
     5701 gaccaacacg attccttttg gctggaagcc ttatgctgtc aaagaagtcc cagttaatga
     5761 taagtcagtc aaggtgggct ttatcggtgt tgtgacaaca gaaattccaa accttgtcct
     5821 aaaacaaaat tatgaacaat atgattacct agactctgca gaaaccatcg ttaaatatgc
     5881 taaagagctc caagagcagc aggtcaatgc gattgttgtc ctagctcata tcccagcaac
     5941 aagtgataac ggggtagttc atgatgagat ggcagcagtt atggaaaagg ttaaccagct
     6001 ttatcctgag catagtgtgg atattgtctt tgctggtcac aaccaccaat acaccaacgg
     6061 taccattggc acaacacgtg tcgttcaggc tgtttcacag gggaaagcct atgcagatgt
     6121 tcgtggaaca ctagacactg acctcaatga ttttgtagcc actcctgaag caaaggtcat
     6181 tgccgttgct cctggcataa aaacaggcaa tgccgacatt caagccattg ttgatcaagc
     6241 caatgacatt gtcaaaaccg ttaccgagct aaagatcggt acagcagcta cctcttcaac
     6301 gatttctaaa acagaaaacg aagacaagga atctcctgtt ggcaatttga taacaactgc
     6361 ccaattaacc attggtagaa aaaccttccc tcatgttgat tttgccatga caaataatgg
     6421 cggtattcgc gctgacttgg tggtcaaaga ggatcaaacc attacctggg gagctgcaca
     6481 ggctgttcaa ccatttggca atattcttca ggtcgttcaa atgactggcc aacaaatcta
     6541 tgatgtcttg aaccaacaat acgatgaaga ccaaaaatac ttccttcaaa tgtctggact
     6601 caaatacact tatacagcta atgaggctaa cgatccttca acaccgttta aggtagtaaa
     6661 ggcttataaa gataatggtg aagaaattga tccagcagct caatacaccc taatcatcaa
     6721 cgacttccta tatggcggtg gtgatggctt ctccgtcttt aaggacgcta agctactagg
     6781 agccattaat cctgatactg aggtctttat cgaatacatc aaggaccttg aagcagctgg
     6841 aaagactgta agtgctggta ttaacggtgt gaaaacctat gtcactgcca gtcttgaagg
     6901 ctctactcaa agtgatcata ccggcaagca cgagatcatc aaccgcgtct ttaagaatcg
     6961 tgagggcaag gtgcttgcta ctgagcttgt ctctgaccta tttacgcctg ctcaaaatgc
     7021 taatcctgcc acaagcatca agcctctagc agctaaaaag caagctaatg ctgccttacc
     7081 agcaacagga acaagccagc attctgctgc tgccatgaca atcctaggac tactaacctt
     7141 aactggtact agccttttca agaaaaagga aggccaataa aatcgtccta gccataacag
     7201 caataaccga ctgtatctta agcatacagc cggttttctg atttatgtga cgtttatttg
     7261 tttcgcacct gttgagcaag acaaataaac cacccatcta tggactgccc tcattcgtta
     7321 gattttctgt ctaacttttg gggtgcagtt cactaacggg tggtcatgat ttaaatcaat
     7381 atgccctcca gatgatccag ctcatgctgg cagatttgtg caggcaggcc tgtcaatctc
     7441 agggatttct tgtgccaatg tgcatcaagg taatcaacct tgatctcctg ataacgcttt
     7501 gtcttacgtt ggccgattag tgataggcag gattcctctg cctcaaacgc ttcacgctta
     7561 gcaattaata caggattaaa catcaccaaa tccacaaagc ccatgctaat aataataacc
     7621 ctcttgtttt cccctatcat attagcagcc agccccaggc agctatcacg ataataagct
     7681 aaggtatcct gcaggtcttg accaatccaa aggtcctttt tcgttgctgg ctgtgctttt
     7741 tgctgcaaga aaaaggtgtc cttcacgatt tttttgatca tcagcttctc cttgattcat
     7801 tgctctaatc ggcatgcatt gtctagatga ccgatcgtat atcttaacgt cattgagcta
     7861 agattaatgt gctaacccta ctgatatatt cagcatatac cagccacagc tcttaaacga
     7921 ttccctgtgc tgacatggcc tgagcaactt tgagaaagcc tgcaatatta gctcccacca
     7981 ctaggttgcc ttcttgacca cattccttgg cggcagcggc tgctttttga taaatagcct
     8041 tcatgatgtc atacaatcga tgatccacct cttcaaaggt ccatgcggta cgtccgctat
     8101 tttgtgccat ttccagcgca gaaactgcta caccgccagc atttgctgct ttagcaggtc
     8161 caaaaagaac cccagcctgc tgaaattgct caatagcctc taaggttgag ggcatgttag
     8221 ccccttcgac aacagcttta accccatgct caatcaaggc tttagcatct gcctcttgta
     8281 gctcattttg agtcgcacat ggaaaggcaa ggtctgcctt aatagtccag atggatccct
     8341 caccagccgg tgtaaacaca gcagccgggt gactctctag ataggtcttg atacgctcac
     8401 gcttcacttc cttgatttgc tttagggtct caagatcaat gcccttatca tcataaacgt
     8461 aaccagagga atccgacact gctaatacct taacacctaa ggcctgcaat ttttccgttg
     8521 cgtaaatggc aacatttcct gatccagata caatagctgt tttaccagcc aagtcctgcc
     8581 ccttagccgc cagcatttgc tgagcaaaat aaaccacacc atagcctgtg gcctctgtgc
     8641 gagccaaaga gccaccataa gctaagcctt ttcctgtcaa cacaccattc ttaaagccat
     8701 taagacgctt atattgccca aataaatagc caatttcgcg agcccctaca ccaatatcac
     8761 cagcaggaac atcaaggtca ggtccaatat gcctttgcag ctctgtcata aagctttgtg
     8821 tgaagcgcat gatttctagg tctgatttgc ctttaggatc aaaatttgat cctccttttc
     8881 ctcctccaat aggctgacca gtcagagcat ttttgaaaat ctgctcaaag ccaagaaatt
     8941 taactataga ctggttaaca gaagggtgaa agcgaagccc tcccttatat ggaccgatag
     9001 ctgatgaaaa ttgcacgcgg tagccacgat taacttggac cctgccctgg tcatcaaccc
     9061 aaggcaccct aaaggaaatc acacgctcag gctcaaccaa gcgctctaat agattttcct
     9121 caatataatt agggtatttt tcaaaaacag gaatcaagga atcaaatacc tccttgaccg
     9181 cctgaagaaa ttcagtctca tgcggattat cccttttgac cttatcaaaa acactggcta
     9241 catagtcttt tgctgatacc attatatatc ctctcgcttc ttcattctat tttaagtata
     9301 gtcaatatta taaattttct gaattttgat gtcaagcttt tactatgatc taaagcaaat
     9361 taaaagagcc ttggaacgat tcattccaag accctaagct ttttaagact gactggtctt
     9421 aaattggcta tgataaagct cataatagaa gcccttagca gctaataggc tgtcatgatt
     9481 cccctgctcg ataatctgac catcttttag aactaaaatc ttatccgcct cttgaatggt
     9541 tgataagcgg tgagcaataa caaagctagt cctgccaacc attaatcgct tcatcgcctt
     9601 ttgaatcaaa agctctaaac gtgtatcaac agacgaggtg gcctcatcta ggattagcag
     9661 ctttggatct gctaagagag ctcgagcaat ggtcagcagc tgcttttgcc ccagggaaat
     9721 attgctagat tcctgattca tcaccatatg atagccacct ggcaatgtcc taatgaaatg
     9781 atcaacattg gcagccttag cagcctcaat tatttgttca tcagtcgcct ctaaatgacc
     9841 aaagcgcaag ttttcctgaa tgctgccctc aaagagccaa gcgtcctgca gcaccatacc
     9901 aaactgacgc ctataggctt gacgtgacaa ctgacgaatg tcctgaccat caactgtgat
     9961 agagccctca ttcacatcat aaaaccgcat taataaatta atcagggtgg tcttgccggc
    10021 tcctgtcgga ccaacgatag ctaccatctc accaggctta acctctaaat tgaaatttct
    10081 aatcagagga ttgtctgctg tatagctaaa atcaacctga ttaaaggaca cctgacctgt
    10141 taaatcatgt tctaaatgct cttgggcaat agtcaattca tctgcctcat caagcactgc
    10201 aaagatacgt tctaaggatg acttggcact ttgcagtgga ccagccagct gtgttatggt
    10261 ctgaataggc tgactgattt gccaaatgta ctgaacaaag gcttgcatgt ttgttcccga
    10321 ttgtcaggcg gcctgctatc acctgtaagc cagcgattaa ggcaacaatc atgtaaacag
    10381 aatctgaaat aaaatgcaga actggcatca tgatcccaga aataaagctg gccttaaagc
    10441 ctacttcttg taatcgctca gtgatctggt gaaattcctc ctttgaggct tcttcacgac
    10501 catacagttt taaaatatta aagccggtca aattttcctg cacaaagcca ttcatttctc
    10561 ccaaaatatt agcctgcgct ttaaaataag gctgtgattt ttttaaaaca aatcgagaag
    10621 cagcatatat caacgggata gcgataatca caacagaggc taggggggca ttaatataca
    10681 agaccatgcc aaccaccaaa ataagggtaa aaaaggcgtt aacaatctgt aaaaaggact
    10741 gctgtaaggc attagagact gtctcaacat cagaggtaaa ccggcctagc atatcgccga
    10801 actgatgctt atcaaaataa gacacaggga tacgattaat tttttgactg aggtctcgac
    10861 gaagatcaca aatgcttgat tgcacagccc ttgtcataaa atagtttgaa ccataagagc
    10921 ctaactcgta aacaagggcc ctaatgatat agagagctaa aagaaaggcg atataggttt
    10981 tattaatgcc tgcaccagag actccctttg ctatgtctaa taggtttgca gatagctctg
    11041 ttatcaccaa gccaagaaca aagggctcta agacactcat cacagcactg actattttta
    11101 aaataatggc agttattagt gagagcctat aggcactaag gtaggtccaa attcttctaa
    11161 acacatgctt ttcagtcatt aatccccctc ctcttttgtc atgtcttcct tgtttagctg
    11221 agaattggca atttcacgat agatggcatt gcttgtaagc aattcctcat gtgtacctcg
    11281 gccaacaatt tctccctgat ccaagacaat gatttgatca gcatccataa tcgtgcccac
    11341 cctttgagcc acaattaaga ccgttgcatc ttgtgtcacc tctttcagcc gtctgcgtaa
    11401 ttcagcatct gtcttgtaat ctagggcaga aaaggaatcg tcaaagatat agatgtctgg
    11461 ctgcttgacc actgctctgg caatagacag gcgctgcttt tgccctcctg atagattact
    11521 gccggcctca gctagatggg tttgatagcc cttttcacga ctggtaataa agtccttcgc
    11581 ttgggaaacc tctgttgcct gctcaagctc actgtggctg gcatctgact taccatattt
    11641 taggttttcc tcaatggttc ctgtaaatag cagggctttt tgaggaataa agccgatttt
    11701 agaacgcagc gcttttaatt gataatccct gacatcaatg ccatcaacca agattctccc
    11761 taaggtcacg tcataaaatc gtgggatcag attaaccaaa gatgattttc ctgaacctgt
    11821 cgagccgata aaagcaatgg tctctccagg cctagtctta aatgagatgt tatgtaaaac
    11881 tggactttcc gtttcacccg gataggcaaa ggtcacgtta tcaaattcta gataaccacg
    11941 tgttgtgaac gctgttatac catcttcatt tttaggaatc gaaatcggca tatccagcac
    12001 ttccttgata cgcttgcttg acactgctgt tttagggtac atggtaaaga ggttggcaaa
    12061 cattaaaaat gaaaaaagag catgaaagct atattcgata aaggccacca aatcaccaat
    12121 cttaaactgc ccccttgcca agggatccaa ggcaaaccag acgatcccca caatcatagc
    12181 aatgataatt tgcacaaata agggctctgt taagcctgtc aaggtaaata gtcgctttga
    12241 gattccagaa tagtgatcat tgcgcttatt gaagcgctct tcttgaaagt cttctcttgc
    12301 aaaggctcga ataactctca gacctgtcag gttttcacgc accaattggt taatacgatc
    12361 aaggctctcc tgctgctttt ctgataaggg tcttgtcttt atcgcaacat aaagcaccac
    12421 aataactaaa aaaggcatgg caacagccac aatccaagcc aatgatggac tggttaaaaa
    12481 gatcatcacc actgaaaaga tcatcatcaa aggagttacg acacccagcc tcaaggacat
    12541 ttcagcaaat tgcatcaaaa caaaggcatc atttgttatc cgagtaacca gggaggctat
    12601 gccaattttt tcatattccg aatgcgaata atcctgcaag cagctataca tgtcattacg
    12661 taaatccttg atcatgttgg tggttagctt acccgaagca taggataaaa tcacccgtcc
    12721 aatgacacct aaaagtacga taataaacat catcagagcc caaaaataaa gagccctttg
    12781 atcctgctgc ataacgcctt gatcaatcat acgagccaat attgttggta gccccagatt
    12841 gaccagaaca aataacaagc cacccacaat atcgaaacaa atccatttag gtcttgtttt
    12901 taaataggac caaattaaag ccattcattt cctcccaaat aatagtgata tgaaaagaag
    12961 cgcaagctag cacttctttt tgtctataac tagtttaaca caaaaatatg aaattgacac
    13021 ataattaatt attcttctaa ttcgcttagg taatcaaagc gctcataggc ttcaagcagc
    13081 tcaagattcc gctgatccag ctccttttga tattgtgcca attggtcgta atcacttgcc
    13141 gctctgagca tttgctcctc aatagtagct atttgttgct cgatagcagc tagcttttct
    13201 tcaatagctg cccattcctt tttctcaaga taggacattc tctttttaga ggtgacctga
    13261 tggtcagtgc cagctttttg ctcactgaca gcaggctcta tgacctctgc ttcaaaagcc
    13321 ttttcatcta aatagtcgct atagttacca tagtattctc tgatagctcc atgctcaaaa
    13381 gccaatactt ttgttgcaac cttatccaag aaataccgat catgactcac tgtaatgacc
    13441 ggaccagcaa attgagctaa aaaatgctcc aacactgtca aggttgcaat atccaaatca
    13501 ttggtcggct catccagcag caggacgttg ggcttttcga tcaagagctt tagcaaatac
    13561 agtctttttt ctccccgcct gatagcttag cgattaagga gccatgacta gaacgcggaa
    13621 aaagaaattg ctccaaaagc tcactgatgc tagtggtgcc aacactggtc ttgacctcat
    13681 ctgccacctc ctgcaaatag ctaatcacgc gcttgctgcc gtccatatcc ttgatttgct
    13741 gtgaaaaata accaatacgg atcgtctcgc caatctctag ctgaccagct gttggtttta
    13801 agtcaccagt catcaagcta agcagggtgg tctttccagc accgttagct ccaacaatgc
    13861 cgatacggtc cttattttga atgatcaggt taaaatgctc aataatggcc tgatcaccat
    13921 aagcaaagga aacctccttg aaattaatga ccttcttgcc aatacgactg gcttcaaagg
    13981 ccatatctaa ttgatctata ggcctttcct gatgaaggtc cttttttaac tgttcaaagc
    14041 ggttaattct ggcctgctgc ttggtcgcac gcgcctgtgg ctgtgtcctc atccaagcca
    14101 gctcctgttt atagagctgc tttttcttat gcaaatgagc tgcttcgcgc tcgtcttgct
    14161 cagccttcag acgcacataa tcctggtaat tgccctgata ttcagtcaca tgagccttat
    14221 ccaattcaaa gatacgtgtg gctatactat ccaaaaaata gcgatcatgt gtaataaata
    14281 gaacagtcct tttagaggtc cttaagtaat gacttaacca agcgatggta tcaatatcca
    14341 aatgattggt cggctcatct agcagcaaca aatcactggc tccaagcaag acctgagcca
    14401 gctgtacccg acgtctcata ccaccggaca ggtcacccac tctctgatcc agattgacaa
    14461 taccaagctt tgataagacc gtcttaacct cactttcgat cgaccaaaca tctaatcgat
    14521 ccatctcagt catcacctct gctagctttt cctgattgct atctgaatag tcagccatca
    14581 acagctcata ttggcgaatc agctgcattt cctttaattc tagggacaga acagtatcta
    14641 aaacagactg atcatcatca aagtccggct cctgtgttaa ataagatata cgatagtcat
    14701 ttgcctttga aaaaggtgag cggtcaccat caaagcccac tttttcagaa ataacatcaa
    14761 gcaaggttgt ttttcctgtc ccattgacac caataatgcc aatgcgatca ccagcatgaa
    14821 taataaagga aatatcctga aaaacggtct tatctccaac agacttcgtc agatgttcaa
    14881 cgataaaatc actcatttag tagttccctt ctaacaaaag cctcaatgtg ttctctttga
    14941 ttgacgagac gcccctctac aatggcctgc tcaatctgat ttaaaagcat tcccagctgt
    15001 ggtcctggct tcattccaag ctcacgaatc agataagagc cattgaccac aatatcatgc
    15061 ttatcatgga tcgtcagctc ctgatacaag ctctcaacac gcttggcctc actgaccaag
    15121 ccctgtgcct gtcgtaaatc gtcaacgagt aaagccaagt ccttgccaaa cgagtaaata
    15181 tcccattttt ctagctgtct ttcttggcga atctgataaa gagaggccat catcgtaacc
    15241 ctacgctgaa aatcattaga ggttttccaa gcctttaaaa aggctttagg ctgatcaagc
    15301 tccagcataa ccagcaaata ggcccaagcc tgatgattgt cctgaaacac ataatccgct
    15361 gctaaggttt tcaggtactt ttgcagggct tcttccttgc ccactaagcc tggcaaatag
    15421 ttaaaggcct gacatgccac catagctaag atacctttac gccattttgg ggccattaaa
    15481 agcttatcaa gctcaataaa agagcgctca atagaaatct tctccagcaa gggagcatgg
    15541 cttttcattg cttcaaaggt ctcagcctca atatcaaaat ctaagctggc agcaaaccga
    15601 aagcctcgca taatccgcag ggcatcctcc tcaaagcgct cctgaggcct tccaacagct
    15661 cttagaagct tatgctttag gtcctctaag ccattaaaga tatcaataac ctgtccgtcc
    15721 tcatctaagg caagagcatt gacagtaaaa tcccttcgtt ttaaatcctc ttccaaggac
    15781 cgaacaaagg atacctgact agggcgccta taatccacat aaacgtcctc agttcgaaac
    15841 gttgtgatct catattcact gccattttct aaaacaagca ctgtgccatg ctcaatccca
    15901 acatcaattg ttcttaagaa aatagccttt gtctcctctg gatagcagct agcagctata
    15961 tcaacatcat gaataggcct gtttaataag ctatccctca cacttccacc aacaaaatag
    16021 gcctcaaagc cagcctgctt gatttttttc actattggta aagccttctg aaattcagaa
    16081 ggcattgtca ttaatgttat catgttttaa tctaccacct aaaagctcct agagccttgt
    16141 catatgcttc ccgttaaagg ctgtcatatc aagctcagat tggtcatggg caagcctctt
    16201 tagacaagag gcgttatgcc aaaggcaaca gctccttctc caagatgggc tgcaatcact
    16261 gcaccaaaat gaacctcctc aacagggcag gtatagccat tatccaacaa gagctgcttt
    16321 aagatatcag ccttatcctg cgctctagca tggataattg atacctcgta ctgaccacta
    16381 gctgtcaatt cctttaagat atcaaccaag cgcttcatgg cctttttttc cgttctaacc
    16441 ttttcataga cgacaatctt tccttcacta tcaaagcgaa gaattggctt gatgctgagc
    16501 aaatttccca gcaaagcaga accgtttgat aagcgtcctc ccttgaccaa atgattcaaa
    16561 tcatcaacca tgataaaggc tgtggttcca gcgatttgct cttctagctt atccataatc
    16621 tctgcaaagc tcaagccttg ctgagaccac tctaaagcat ttctaaccat gctgcctaat
    16681 ggtgctgagg tgattttact atctggaaaa gcaatggtca actcagggtg ctcctcgatg
    16741 agaaattgaa tattttgcca aaatcctgaa ataccactag ccaagaacaa gccaatcaca
    16801 tgagtatagt gctcagttga cagacgccct agtaaatcat ctaattcaga gaggctgggc
    16861 tgactggttt ttggcagctc ttgagattct ctcatgcttt ggtaaaaggc ttcaatggtc
    16921 aggttttgtc cttcgacata gctttgacca tctatgatta caggtatgtc taatacaaaa
    16981 atatcggcat gctccgctaa ctgctctgga aggtgagctg tattatcagt tattattgct
    17041 aacttcatta acttttaaac tccaaattaa taccaggacg atccaaggca atttctgtca
    17101 cttcgtaggt caagcgcttc accatgtcta ataatggagc agccaaggat tcgacctcct
    17161 cttgtgtaaa ttcactaggc ttatccacca agcgtcctaa aatacgaacc atctgtgaaa
    17221 tcacaccact aatcacaaac tcttccttga caatgacaaa ttgtaaaaca gaaacaatag
    17281 ccgtctcttt attttccaca tctttattaa tcaactgaaa ggttacttca aagtttgttt
    17341 ccggtgttcc attttctttt tcccattcta aatttctggc gtcataatgg tactgattga
    17401 caaattcttt ttcacgtact aattgcatga tttcgttctc cttaatggcg atatgaccca
    17461 ttatagcata gatttgacga atattaaagt agacttaaac cagtattttg gataattttt
    17521 ttccagacct tgtcacttca ataaatataa acctgccttc tatcaaccaa tcaatctcct
    17581 acaacaaaaa aacaccccaa ggtgtactgc ccccaaaaag ttgaacgaat aattattgaa
    17641 aggatttagt tctgtattga acagg
//
LOCUS       DARYYD010000040        17409 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.040, whole genome shotgun sequence.
ACCESSION   DARYYD010000040 DARYYD010000000
VERSION     DARYYD010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17409
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.040"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            111..722
                     /locus_tag="TV188_001389"
     CDS             111..722
                     /locus_tag="TV188_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HEL1534733.1"
                     /translation="MFKQDILKQRYFSFGIVAAAIALLAVVFAFSSENVNTDSYAKAS
                     DTKVVKKHHKTKKSTVAKAATKEQPAEQAEPSSADAAPAQESVASEVASPAVQEAAPQ
                     AQYAATPVAYSNGVILSNGNTAGAIGSEAAAQMAAATGVPQATWEAIIARESNGNPNA
                     ANPSGASGLFQTMPGWGSTATVQDQVNSALNAYRAQGLSAWGY"
     gene            complement(783..1418)
                     /locus_tag="TV188_001390"
     CDS             complement(783..1418)
                     /locus_tag="TV188_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase-like protein"
                     /protein_id="HEL1534734.1"
                     /translation="MKAILFDLDGTLVDSSIGILNAFEYTFQKMKIPCPDHSILSSYI
                     GPPLEATFSAFFRNQHDVEVAITHFRDFYRELGIYQARLYSGITELLDNLSQEGLDLY
                     VTTSKYEPMARQMLQDLTISHYFKAILGSISNRCHKLDIVKACLQDFAINKKEAIIVG
                     DTKFDMIGGKQAGITRLGVTWGFGCQEDLQAHGAQYIGHTPQEVIEIIQSL"
     gene            complement(1452..2324)
                     /gene="sdaAA"
                     /locus_tag="TV188_001391"
     CDS             complement(1452..2324)
                     /gene="sdaAA"
                     /locus_tag="TV188_001391"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEL1534735.1"
                     /translation="MFYTIEELVKQADDRFDGNVAELMIATEVEMTGRSRAEILSIMS
                     QHLQVMKDSVVSGLTATKSISGLTGGDALKMDHYIKKGKGLSDQTILTAVRNAMAVNE
                     LNAKMGLVCATPTAGSAGCLPAVLAVAIDKLKLSEKEQLDFLFTAGAFGLVIGNNASI
                     SGAEGGCQAEVGSASAMSAAALVKAAGGTAYQASQAVAFVIKNLLGLVCDPVAGLVEV
                     PCVKRNALGSSFALVAADMALANIQSQIPVDEVVDAMYQVGAAMPTAFKETAEGGLAA
                     TPTGRRYSKEIFGD"
     gene            complement(2336..3007)
                     /gene="sdaAB"
                     /locus_tag="TV188_001392"
     CDS             complement(2336..3007)
                     /gene="sdaAB"
                     /locus_tag="TV188_001392"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEL1534736.1"
                     /translation="MNTQKFQSVFDIIGPVMIGPSSSHTAGAVRIGKVVHSIFGEIPD
                     EVTFHLYNSFAKTYQGHGTDKALVAGIMGMDTDNPNIKNSLEIAHQKGIKIYWDILKD
                     SNAPHPNTVKISVKKADKAMSITGVSIGGGNIQVTELNGFSVSLSMNTPTLIIVHQDI
                     PGMIAKVTDILSASDINIAQMTVTRESAGEKAIMIIEVDSRDCQVAVKQIATIPNLHN
                     VNFFD"
     gene            3288..4412
                     /gene="mnmA"
                     /locus_tag="TV188_001393"
     CDS             3288..4412
                     /gene="mnmA"
                     /locus_tag="TV188_001393"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEL1534737.1"
                     /translation="MMTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGVFMKNWDD
                     TDEFGVCTATEDYKDVAAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRSGRTPNPDV
                     MCNKEIKFKAFLDYAMTLGADYVATGHYAQIKRDENGVVHMLRGLDKGKDQTYFLSQL
                     SQEQLQKTMFPLGHLQKSEVRAIAEQAGLATAKKKDSTGICFISEKNFKTFLSHYLPA
                     QKGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQQGGDNKPWFVVGKDLSQNILYVG
                     QGFYHESLMSTSLDASVIQFTREVPEEFTLECTAKFRYRQPDSKVTVHVKKDKAKVVF
                     AEPQRAITPGQAVVFYDGHECLGGGIIDMAYKDGEPCQYI"
     gene            4617..5081
                     /locus_tag="TV188_001394"
     CDS             4617..5081
                     /locus_tag="TV188_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1534738.1"
                     /translation="MVQDFRTRIADHSFGVRASALIIKDGYIYLAKSPKEDYYLLGGA
                     IHVGESTEEAVKREVLEEVGAEVSVAQLAFVVENQFCLEGVNFHQIEFHYIVSLLSDS
                     SPSVVEGDCTRVCEWVALDDLDKIRLNPSCLKRAIKHWDRQPQHIKHIEIKE"
     gene            5084..6982
                     /gene="mnmG"
                     /locus_tag="TV188_001395"
     CDS             5084..6982
                     /gene="mnmG"
                     /locus_tag="TV188_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEL1534739.1"
                     /translation="MVHEFTESYDVIVVGAGHAGVEASLAASRMGCKTLLATINLDML
                     AFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KSLYAREMKHTVEKQENLTLRQSMIDDILVENGRVVGVLTATGQKYAAQAVIITTGTA
                     LRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSIDYEVTE
                     IQPGDVTPNHFSFMSKDKDYLANQIPCWLTYTNQISHDIITKNLYRAPMFSGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGFDTEEVYVQGLSTSLPEDVQKELVHSIKGL
                     ENAEMMRTGYAIEYDIVLPHQLRATLETKMISGLFTAGQTNGTSGYEEAAGQGLVAGI
                     NAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMR
                     LTEIGRQIGLVDDERWSAFEIKKNQFDNELKRLDSIKLKPIKETNARVQKLGFKSLTD
                     AMTAKEFMRRPEVDYATVVSFIGPAAEGLDAKLIELLETEIKYEGYIKKALDQVAKMK
                     RMEEKRIPKTIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEG
                     NGKARRKT"
     gene            7070..9046
                     /locus_tag="TV188_001396"
     CDS             7070..9046
                     /locus_tag="TV188_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEL1534740.1"
                     /translation="MKRFRFETIHLIMMELILFGLLALCVRIMQSKMLITLAIFLVLL
                     FVAALLWYQKKVYELSDLDHIELLNEQTENNLKTLLDNMPVGVIQFDQETNAIEWYNP
                     YAELIFTDEAGFLQEQMIQQLLTDKRKSDISQTFEVSGNRYTSYIDVASGIFYFFDSS
                     VGSRQSADSSLLKPVIGIISVDNYDDITDDLSDADTSKINSFVANFIAEFMESKQVFY
                     RRVNMDRFYFFTDYKILKGLMDDKFSILEQFRKEAQEAQLPLTLSMGISFGEENHCQI
                     GQVALENLNIALVRGGDQIVIRENADHTNPVYFGGGSVSTVKRSRTRTRAMMTAISDR
                     IKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSPDIERAIERLQ
                     ADGKTRLISISQAMGLTTPRSLLVMVDHSKISLTLSKEFYEQFQDVIVVDHHRRDDDF
                     PDNAILTFIESGASSAAELVTELIQFQNAKKRLNKIQASVLMAGIMLDTKNFSTRVTS
                     RTFDVASYLRSRGSDSVEIQNISATDFDDYKQVNEIILRGERLSDSIIVATGLAGQYY
                     SNVIASKAADTILSMAHIEASFVIVETGADKIAISARSRSKINVQRMMEKLGGGGHFN
                     LAACQMKHISLSEAKQLLLETIDNTMKETREVES"
     gene            9043..9495
                     /gene="rplI"
                     /locus_tag="TV188_001397"
     CDS             9043..9495
                     /gene="rplI"
                     /locus_tag="TV188_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEL1534741.1"
                     /translation="MKVIFLVDVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEASSQAI
                     GQLRGQQKAEEKAQAEILAEAKAVKKILDDEKTRVQFKEKVGPDGRTFGSITAKKISE
                     ELQKQFKVKVDKRHIVLDHPIRAIGLIEVPVKLHKEVTAEIKLNIAEA"
     gene            9516..10892
                     /gene="dnaB"
                     /locus_tag="TV188_001398"
     CDS             9516..10892
                     /gene="dnaB"
                     /locus_tag="TV188_001398"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEL1534742.1"
                     /translation="MEVLSLPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFIG
                     PEDFYKYSHKVIFRAMIRLSDRNDAIDATTVRTILDDQGDLQHIGGLSYIVELVNSVP
                     TSANAEYYAKIVAEKAMLRDIINRLTETVNLAYEGASDSEDIIASAEKALVDISEHSN
                     RSGFRKISDVLKINYENLEVRSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPA
                     VGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVNSHSLRTGQLTDQ
                     DWNNVTIAQGALAEAPIYIDDTPGIKITEIRARARKLSQEVEGGLGLIVIDYLQLITG
                     TRPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIE
                     QDADIVAFLYRDDYYRKESDSTEEALEDNTIEVILEKNRAGARGTVKLMFQKEYNKFS
                     TIAQFEER"
     gene            10909..11181
                     /locus_tag="TV188_001399"
     CDS             10909..11181
                     /locus_tag="TV188_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HEL1534743.1"
                     /translation="MSDAFTDVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKVGRL
                     IEVYPSLFIIEYQGNPDASGEANNSYVESYTYSDILTEKTLIRYFD"
     gene            11705..12316
                     /gene="rpsD"
                     /locus_tag="TV188_001400"
     CDS             11705..12316
                     /gene="rpsD"
                     /locus_tag="TV188_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEL1534744.1"
                     /translation="MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFSYGMGEKQFRNLFVQATKIKEGTLGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSFRVEIGQVISVREKSMKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(12523..13056)
                     /locus_tag="TV188_001401"
     CDS             complement(12523..13056)
                     /locus_tag="TV188_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1534745.1"
                     /translation="MDSRKQQTKKAILNAMVSLLKTESFDDVTTVQLAKMAGISRSSF
                     YTHYKDKYEMIDYYQQTFFHKLEYIFEKEYQNKEHAFLEVFEFLKREQLLSALLSSNG
                     TREIQSFIINKVRLLITTDLQDKFSKDILSPTEKEYRSIYLAHAFFGVCQSWIAKGKK
                     ESPQEMTRFVLKMLSKT"
     gene            13188..15470
                     /locus_tag="TV188_001402"
     CDS             13188..15470
                     /locus_tag="TV188_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HEL1534746.1"
                     /translation="MLEGLKAIIKNRKLVVTMIGVALVPALYNLSFLGSMWDPYGRVD
                     QLPVAVVNQDKPAYLNNKRLTIGNDMVDNMSKNKELDYHFVAADTAQKGLEKGRYYMT
                     ITLPKDLSQKATTLLDQQPEKLIVSYQTSKGHSFIASKMGESAMNHLREAVSKNIRKT
                     YITSVFKSMHQLQSGLKEASNGGQQLAAGLVIARASSQLMSRHLNTLSESSARLSQGA
                     GNLSSGIAAYTAGVGQLDTAGLGQLAADMPAYLDGVSRLSKGANQLNAGLTQLALGSD
                     LSQDKQANIQALMASLPKLNQAIQQLKTNLSLSLAPNVDSGAIAKHLADMTRLVQELV
                     VDDTADKNNQLAALQATATYQGLNSEQQEELSSAISNTSTKVTISAKAMLTSLQAMSE
                     ELEAMSTSAGVADQLRDFKALVNQLAYQADQILPSTGKALSELSTGLRAVHSATTAQL
                     LSGSQALAGGFNQLTAKNEALTAGLSTLATGATALNHQSSQLLAGGQQLTVGANQLAF
                     GANQLSSGSSQLTDGLTTLSTGLSSLTTSLSKASDQLSMAWVEDQNADMVSDPVALSE
                     KDKDKVRTNGIGMAPYMIAVSLMVVALSTNIIFAEALSGKPIKDRWDWAKQKLLINGM
                     ISTVGSVILYAALQLLGFEANDGIKTLGFIMLSGWALMALVTALVSWDARYGAFASLI
                     MLLLQVGAAGGSYPIELSGQIFQILHPYLPMSYIVSGLRQTISLTAQIGLETSVLVGF
                     LLSFMAIGVLIYRPKDKQSS"
     gene            complement(15574..16629)
                     /locus_tag="TV188_001403"
     CDS             complement(15574..16629)
                     /locus_tag="TV188_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HEL1534747.1"
                     /translation="MTKQDFLDKLKQQINHLPQKDYQEIIDHFTEYFDEAGPDHEQAI
                     LKELGNPEDIAKELLKALDLPEKTDEDDWTNWEVDNKTKSEASSQKLEPIVDIRYSLL
                     NHDLTIETADIPYPTISYDDNRITISQDSDGMLNIIEDSAVQTIQYGFHFLDRWLAKY
                     QPITLTLPVNHHLKKISGESDNNDVTIRHIHCDSIVSNTYNGTISISHLSDSTVNLSS
                     KNGNIILEHCNIQSSKCQAKNANLSCDNSTLINCQLNNNNGNIRLEASQLTETFIENK
                     NGNIIGQQLSFSNDITIINKNGIIDINCPRENLIYYDVKASNNNGFVTISQEAGRQTP
                     FKAQLTISNNNGLISVS"
     gene            complement(16648..17073)
                     /locus_tag="TV188_001404"
     CDS             complement(16648..17073)
                     /locus_tag="TV188_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534748.1"
                     /translation="MTRDEYLAELDKYLRKLPKADYYEAAENSSQLELNDGSIKDSSI
                     TVADTKEENDYDYTDPSELAINHVTIKEKNTINGGDININTTLANPRDIAYHVTTRGN
                     IKLSSRFSNAKLNTDAATGATSFHSDIANTVNQSDLSIH"
     gene            complement(17060..17386)
                     /locus_tag="TV188_001405"
     CDS             complement(17060..17386)
                     /locus_tag="TV188_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019314866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEL1534749.1"
                     /translation="MYFPVSATLIEFLILSIVDKHDSYGYDISQTIKLVANIRESTLY
                     PILKKLEKSDYLTTYSQEHQGRKRNYYTITAKGEKQLIFLKEEWQSYKATLDGIIEGR
                     LRHDKR"
BASE COUNT         5062 a         3170 c         3851 g         5326 t
ORIGIN      
        1 tagaaaactt ggaatatcaa tattgctgta atatttttaa tatatcttaa atagacaagt
       61 aataattaac agttaatatg gataacagag aaaagtgagg tatttattta atgtttaaac
      121 aagacatttt gaaacaacgt tattttagtt ttggcattgt agcagctgct attgctttgc
      181 tcgcagtagt ttttgctttt tcaagtgaaa atgtaaacac tgattcctat gctaaagctt
      241 ctgatactaa ggttgtgaag aaacatcata aaacaaaaaa atcaacagta gcaaaggctg
      301 caaccaagga gcagccagct gagcaggcag agccttcctc tgctgatgca gcaccagctc
      361 aggaatcagt agcttctgag gtagctagtc ctgctgtgca agaggctgct cctcaagctc
      421 agtatgcagc tacaccagtg gcttatagca atggagtaat cctttctaac ggcaataccg
      481 caggggctat cggtagtgaa gcagcagctc aaatggcggc agctactggt gttccacaag
      541 ctacttggga agccattatc gctcgtgagt caaatggaaa ccctaacgca gctaatcctt
      601 caggtgcttc aggattattc caaaccatgc caggctgggg atcaactgca accgttcagg
      661 atcaggtaaa ttcagcctta aatgcctatc gtgcacaggg cttatcagct tggggctact
      721 aagaacagat aacagcgtta aaaacctatc atcttgtgtg atgataggtt tttagtatcg
      781 ttttacaatg actggataat ctcaatcacc tcttggggtg tgtgtccaat gtattgtgcg
      841 ccatgtgctt gtaaatcctc ttgacaacca aatccccaag taactccaag tcttgtaatg
      901 cctgcttgtt taccaccaat catgtcaaat ttggtatctc caacaattat agcttctttt
      961 ttattaatag caaaatcttg taagcatgcc ttgacgatat ccaacttgtg acaccgatta
     1021 gaaatagagc ctaggatagc tttgaaataa tggctaatcg ttaaatcctg aagcatttgc
     1081 cttgccatag gttcatattt actagttgtc acatagaggt caagaccttc ttgcgagaga
     1141 ttatctaata gctctgtgat tccagaataa agccttgctt ggtaaatgcc taattccctg
     1201 taaaaatctc taaagtgtgt tatagcaacc tcgacatcat gctgattcct aaaaaatgct
     1261 gaaaaggtcg cttctaaggg tggtccgatg taagacgata atatgctatg atcaggacaa
     1321 gggattttca ttttttgaaa ggtgtattca aaggcattta gtattcctat actagaatcc
     1381 accaaagtac catctaagtc aaataggatt gctttcatga cgtctcctca gtctatcgtt
     1441 acttgattat attagtctcc gaaaatttct ttactatacc gtctacctgt tggggttgct
     1501 gctaatcctc cctcagctgt ctccttaaag gctgttggca ttgcggcacc aacctgatac
     1561 atagcatcaa caacctcatc tacaggaatt tgtgactgaa tattcgctaa tgccatatca
     1621 gcagcaacaa gagcaaagct tgatcctaat gcattacgct taacacaggg aacttcgact
     1681 aagccagcaa caggatcaca aaccaatccc aatagatttt tgatcacaaa ggctaccgct
     1741 tggctagcct gataagcggt accacctgct gccttaacaa gggctgcagc actcattgca
     1801 gaggcagagc ccacctcggc ttgacagcct ccttctgctc cggagataga ggcattattt
     1861 ccaatgacta agccaaaggc acctgctgta aagagaaagt ccagctgttc cttttctgat
     1921 agcttgagct tatcaatagc aacagcaagg acagcaggta gacagcctgc acttccagca
     1981 gtcggggttg cacaaacaag tcccattttt gcatttagct cattgacagc catagcattt
     2041 ctcacagctg ttaaaatggt ttgatctgaa agcccctttc cttttttgat gtaatgatcc
     2101 atcttaagag catcaccgcc agtcaatccg ctaatagatt tggttgctgt caatccgctg
     2161 acaacagaat ccttcattac ctgtaaatgc tgtgacatga tggataggat ttctgccctg
     2221 cttcgaccag tcatttcaac ctctgtagca atcatcagct ctgctacatt accatcaaac
     2281 ctatcatcag cctgcttgac aagctcttca attgtgtaaa acataatata cctttctagt
     2341 caaagaaatt gacattatgc agattaggaa tagttgcaat ctgcttgaca gcaacttgac
     2401 aatcacgaga atcaacctca ataatcataa tggctttctc acctgcactt tcacgagtca
     2461 cagtcatttg agcgatatta atatcactag ctgacaatat atctgtaacc ttagcaatca
     2521 ttccggggat atcttgatgg acaataatca aggttggagt attcatagac aaggaaacag
     2581 aaaaaccatt tagctctgtg acctgaatgt ttcctcctcc aattgacaca cctgtaatgc
     2641 tcattgcttt atcagccttt ttgacactaa tctttacagt attggggtgg ggagcattgc
     2701 tatcctttaa aatatcccaa taaattttaa tgcccttttg atgagcaatt tcaagagaat
     2761 tcttgatgtt tggattatcc gtatccatgc ccataatacc agctactagt gccttgtcgg
     2821 taccatggcc ttgataggtc ttagcaaatg aattgtatag atgaaaggtc acctcatcag
     2881 gaatttctcc aaaaatggag tggacaacct ttccgattct aacagcacca gcggtatgac
     2941 tgctcgatgg tccaatcatc actggtccaa tgatgtcaaa aactgattga aatttttgtg
     3001 tgttcatata tgctccatgc tctttttatc ctttttatta taacaaatcg ctaatcaaat
     3061 gtcgtttgtt atgaaaaaag atattgttgg aaataagaga caatactgtt ataatagtca
     3121 tgcgtctagc ggcgcttcaa atcgaccttc aaatcgagct ttgagaaaac acttggacaa
     3181 agacaaaaaa tatagaaatg aaccatttgc tagagtcttg tttaggcaag ttgattcgtt
     3241 ctattctttt tctcatgtcc ttgtatctta tattgatggg agaataaatg atgacagata
     3301 actcgaaaac acgtgttgtt gttggcatga gtggcggtgt tgattcatct gtaactgcct
     3361 tgctgttaaa ggagcaggga tatgatgtga ttggcgtctt tatgaagaat tgggacgata
     3421 cagatgaatt tggtgtttgt acggcgactg aggattataa agatgtggca gccgtagccg
     3481 atcagattgg tattccttac tattctgtta attttgaaaa agagtattgg gatagagtgt
     3541 ttgagtattt cctagcagaa taccgttcag gacgcacccc aaatcctgat gtcatgtgca
     3601 ataaggagat aaagtttaaa gcctttcttg attatgcgat gacattgggt gctgattatg
     3661 tggcaacagg tcactatgcc caaatcaaac gtgatgagaa tggtgtagtc catatgctgc
     3721 gtggtcttga taagggtaag gatcaaacct attttttaag ccaactatca caagagcaac
     3781 tccaaaaaac catgtttccc ttggggcacc tgcaaaaatc agaggtacgt gctattgctg
     3841 aacaagcagg ccttgcaaca gcaaagaaaa aagactcaac agggatttgt tttattagtg
     3901 agaagaattt taagaccttt cttagccatt atttaccagc tcaaaagggg cgtatgatga
     3961 ctgttgatgg tcgtgatatg ggagagcatg caggcttgat gtattatact attggccaac
     4021 gtgggggact tggcattggt ggtcagcagg gtggagataa caagccttgg tttgttgttg
     4081 gaaaagacct ttcacaaaat atcctttatg ttggtcaagg cttttaccac gagtccttaa
     4141 tgtcaactag tcttgacgct tctgtcattc agtttacaag agaagttcct gaagaattca
     4201 ccttagaatg cacagcaaag ttccgctatc gtcagccaga ttctaaggtg acggttcatg
     4261 tcaagaaaga caaagctaag gttgtttttg ctgagcctca gcgtgcgatt acacctggtc
     4321 aagcagtcgt tttttatgat ggtcatgagt gtcttggtgg tggtattatt gatatggcgt
     4381 ataaagatgg cgagccttgt caatatattt agcttgacat gttaattgac agatgtgtca
     4441 ataaagttga cggttttgtc atctgataag tcttgacaag ctggcagatt ttgatagaat
     4501 aaggttaaca ataacgatga tggtcaaagc tcatgggaat tgtaagtctt tttggcttac
     4561 agctttctca ggttttgact atttttatag cttaaaaaca gtgtcaagga gaaaagatgg
     4621 ttcaggattt tagaacaagg atagcagacc atagctttgg tgttagggct tcagcgttaa
     4681 taattaagga tggctatatt tatcttgcca aatcacccaa agaggactat tatcttttag
     4741 gtggtgctat tcatgttgga gaaagcacag aagaagctgt caagcgtgag gttctagagg
     4801 aggtaggagc tgaggtttca gttgctcagt tagcctttgt ggttgaaaat caattttgtc
     4861 tagaaggagt gaactttcat cagattgagt ttcattatat tgtgagtcta ttatctgatt
     4921 ctagcccttc tgtagttgag ggtgattgta ctagggtttg tgagtgggtt gctcttgatg
     4981 atctagataa gataaggctc aatcctagtt gtttaaaaag ggctataaag cattgggaca
     5041 ggcagcctca gcatataaaa catattgaga taaaggagta gatatggtac atgaatttac
     5101 agaatcctac gatgtcatcg ttgtaggagc aggacatgca ggtgttgaag ccagcttagc
     5161 ggctagccgt atggggtgta aaaccttatt agcaacgata aatcttgata tgctggcttt
     5221 tatgccatgc aatccctcta ttggagggtc agctaagggt attgttgttc gcgaaattga
     5281 tgctcttggt ggagagatgg ggaaaaacat tgacaaaacc tatatccaaa tgaaaatgct
     5341 caatacaggt aagggaccgg cagttcgagc attacgagct caagcagata aaagcttgta
     5401 tgcacgtgag atgaagcata ctgttgaaaa gcaagaaaac ctcactcttc gccagtctat
     5461 gattgatgat attttagtag aaaatggtag ggttgttgga gtgctgacag caacagggca
     5521 aaaatatgca gctcaggcag tgatcataac aacaggtaca gctcttcgtg gtgagattat
     5581 ccttggagaa ttgaaatatt cgtctggccc gaataacagc ttggcctcag tgacactagc
     5641 tgataatttg aaaaagcttg gtcttgaaat tggccgcttt aagacaggaa ccccaccacg
     5701 tgtcaaggct tcttctattg attatgaggt gacagagatt cagcctggtg atgtgactcc
     5761 aaatcatttt tcctttatgt ctaaggacaa agattatttg gctaatcaga ttccttgctg
     5821 gctgacctac actaatcaga ttagtcatga tatcatcact aaaaacctat atcgagcacc
     5881 tatgttttca ggagtcgtca agggagtggg cccacgctat tgtccatcaa ttgaggataa
     5941 gattgtacga tttgctgata aagagcgtca tcagctcttt ttagaaccag aaggctttga
     6001 cactgaggag gtctatgttc aaggtctatc cacaagtctt cctgaggacg tccaaaagga
     6061 attggttcac tctattaagg ggcttgaaaa tgctgagatg atgagaacag gctatgctat
     6121 tgagtatgac attgtattac ctcatcagct tcgtgctacc cttgaaacaa agatgatttc
     6181 agggcttttt acagctgggc aaaccaatgg aacctcaggc tatgaggaag ctgctggtca
     6241 aggccttgtc gctggtatca atgctgcttt gaaggttcag ggtaagcctg agctcatttt
     6301 aaagcgcagc gacgcttata ttggtgtaat gattgatgat ttggtaacca aaggaacctt
     6361 ggagccttac cgtttgctga catcacgcgc agaatatcgt cttatccttc gtcatgataa
     6421 tgcggacatg cgattgactg aaattggtcg tcagattggc ttggttgacg atgagcgttg
     6481 gtctgccttt gaaatcaaga aaaatcaatt tgacaatgaa ttaaagaggc tagatagtat
     6541 caaattaaag ccaatcaaag aaaccaatgc tcgtgttcaa aagcttggct ttaagtcctt
     6601 gacggacgca atgacagcta aggaatttat gcgtcgacca gaggttgact atgccactgt
     6661 agtgtcattt ataggtcctg ctgctgaggg attagatgct aagctgattg agctactaga
     6721 aactgagatc aaatacgaag gctatatcaa aaaggccctt gatcaggttg ctaaaatgaa
     6781 gcgtatggag gaaaagcgga ttcctaagac cattgattgg gacgctattg actcaattgc
     6841 tactgaggca aggcaaaaat ttaagaaaat caatccagaa accattggtc aggctagtcg
     6901 catttcaggt gtaaatccgg cagatattag cattttaatg gtttaccttg aaggtaatgg
     6961 aaaggctcgc cgtaaaacat aatagtcatc aaattgtaat ctcaaaacca ctgacagctc
     7021 tgtatttcag ggctgtttta tggtataata cgggattaag aggttaaaga tgaaaagatt
     7081 tcgttttgaa accattcatt taattatgat ggagttgatt ttattcggct tactagcctt
     7141 atgtgttaga atcatgcaat caaaaatgct gattacacta gctatttttt tagtgttgtt
     7201 gtttgttgcg gccttgcttt ggtatcaaaa aaaggtttac gaattgtctg atttagacca
     7261 cattgagcta ttgaacgaac aaacagaaaa taatttaaaa acattactgg ataacatgcc
     7321 agttggtgtt attcagtttg atcaagaaac caatgctatt gaatggtaca atccttacgc
     7381 agagctgatt ttcactgatg aggccggttt tttacaggaa cagatgatcc aacagcttct
     7441 cactgataag cgtaaaagtg atatttctca aacctttgag gtttctggca atcgatacac
     7501 gtcttatatt gatgtggcat caggtatttt ttactttttt gatagctctg ttggtagtag
     7561 acaatcagca gattctagct tgctaaagcc agttattggt attatttctg tggataatta
     7621 tgacgacatt acagatgact tatctgatgc tgatacgtca aagataaatt catttgtggc
     7681 taatttcata gctgagttta tggagtctaa gcaggtattt tatcgacgtg ttaatatgga
     7741 tcgtttttac ttttttacag actataagat cttaaaaggg ctgatggacg ataagttttc
     7801 tattttagag cagttccgaa aggaagccca agaagcgcag ctaccattga ccctaagtat
     7861 gggcatttcc tttggagagg aaaatcattg tcaaattggt caggttgctc ttgagaatct
     7921 gaatattgct cttgtccgag gcggagatca gattgttatt cgtgaaaatg cagaccatac
     7981 aaatccggtc tattttggtg gcggctctgt ttctacggtt aaacgctcta gaactaggac
     8041 gcgtgccatg atgacagcta tttcagaccg tatcaaaatg gttgataatg tgtttatcgt
     8101 aggtcaccgt aaactggaca tggacgcctt aggctcggct gttggcatgc aattttttgc
     8161 tagtaacatt attgaaaaca gctttgctgt ctataatccg gatgagatga gtccagacat
     8221 tgaaagagct attgagcgct tacaggctga tggtaagaca cgtcttatca gtatttctca
     8281 agcaatgggg cttacgaccc ctagatcact gttagtaatg gtggaccact ctaagatttc
     8341 cttaaccttg tctaaggaat tttacgagca atttcaagat gttattgtcg ttgatcatca
     8401 ccgaagagat gatgattttc cagataatgc tatcttgacc tttattgaaa gtggtgcaag
     8461 cagtgccgca gagctagtga cagaattaat ccagtttcaa aatgcgaaga agcgcttaaa
     8521 caagattcaa gcaagtgttt tgatggctgg tattatgctg gatactaaga atttttcaac
     8581 acgtgtcacc agtagaacct ttgatgttgc cagttattta cgaagcagag gtagtgatag
     8641 cgtcgaaatt caaaatattt cagcaactga ttttgatgac tataagcagg ttaatgagat
     8701 cattctcaga ggtgagcgcc ttagcgactc cattatcgtt gcaactgggc ttgctgggca
     8761 atattatagt aatgtcattg ctagtaaggc agcagatacc atactatcaa tggcccatat
     8821 tgaggctagc tttgttattg tagagacagg agctgataag attgctatat cagcaagaag
     8881 tcgtagtaag atcaatgtcc aaagaatgat ggaaaagctt ggcggcggag gacatttcaa
     8941 cttagcagcg tgtcagatga agcatatcag tcttagcgag gctaagcagc tgttactaga
     9001 aacaattgat aacacaatga aagaaacaag agaggtagag tcatgaaagt cattttttta
     9061 gttgacgtta aaggaaaagg aaaaaaagga gaaatcaagg aggttcccac tggttatgct
     9121 cagaattttc tgattaagaa aaatttagca aaggaagcta gcagtcaagc aattggccag
     9181 ctaagagggc agcaaaaagc tgaggaaaaa gcccaggctg aaatcctagc agaggctaag
     9241 gctgttaaga aaatcttaga tgacgaaaaa actcgtgtcc agtttaagga aaaggttgga
     9301 ccagatgggc gtacctttgg ctcaattaca gctaagaaaa tttccgagga attgcaaaag
     9361 caatttaagg tcaaggttga caagcgtcat attgttttag atcaccctat tcgtgctatt
     9421 ggtcttatcg aagtgccagt taagctgcat aaagaagtga cagctgaaat aaaactaaac
     9481 attgctgagg catagcacat cagcctaaaa aagatttgga ggtgctgagt ttgcctgaag
     9541 ttgctgagtt acgagttcaa ccccaagatt tattggcaga gcagtctgta ctaggctcta
     9601 tctttatttc cccagacaag ttgattaccg ttagagaatt tatcggtcca gaggattttt
     9661 ataagtattc tcataaggtc attttcaggg caatgataag gcttagtgat cgaaatgatg
     9721 ctattgatgc aacaacggta aggacgattc ttgatgatca aggggacctt caacatattg
     9781 gtggcttgtc ttatattgtt gagctggtta atagtgtacc taccagtgcc aatgcagaat
     9841 actatgctaa aatagtagct gaaaaggcta tgctacgcga tatcatcaat aggttgacag
     9901 agactgtaaa cttagcctat gaaggagcat ctgactcgga ggatattatt gcaagtgctg
     9961 agaaggcctt ggttgatatc agtgagcata gcaatcgcag tggctttcgt aagatctcag
    10021 acgttttaaa gattaattat gaaaatcttg aggttcgttc taagcagaca tcagacgtta
    10081 caggtttacc aacgggcttt agggatcttg acaagattac aacaggttta cacccagatc
    10141 aactgattat tttagcagct cgtcctgcag tcggtaagac agcctttgtc ttaaacattg
    10201 ctcaaaatgt tggtacaaag caaaagagag cagttgccat tttctcctta gaaatgggag
    10261 ctgaaagcct tgttgatcgt atgctggccg ctgagggaat ggtcaattca catagcttga
    10321 ggactggtca gttgactgat caggactgga ataatgtgac cattgcccaa ggagccttgg
    10381 cagaagcacc tatctatatt gatgatacac ctggcattaa gattactgag atcagagcaa
    10441 gggcacgtaa attgtctcag gaggttgagg gaggcttagg gctaattgtc attgattacc
    10501 tccaactgat cactggtaca agacctgaaa atcgtcagca agaggtttct gatatttcaa
    10561 ggcagctaaa gattttagct aaggaattaa aagtgcctgt tattgctttg agtcagcttt
    10621 ctcgtggtgt tgagcagagg caggacaagc gtccagtttt gtctgatatt cgtgagtctg
    10681 gctctatcga gcaggatgcg gatattgttg catttttgta ccgagatgat tattatcgta
    10741 aagaaagcga cagcacagaa gaggctcttg aggataatac aattgaggtg attcttgaga
    10801 aaaatagggc aggtgcgcgt gggacagtta agctgatgtt tcaaaaggaa tacaataaat
    10861 tttcgacaat agctcaattt gaggaaagat aagaaagagg gaaagagaat gagtgatgca
    10921 tttacagatg ttgccaaaat gaaaaaaata aaggaagaca ttaaggctca tgaaggtcag
    10981 ttggttgagt taacacttga aaatggtcgt aagcgtgaaa aaaataaggt tggcagattg
    11041 atagaggttt acccttcttt atttatcatt gagtatcagg ggaacccaga tgcttcaggg
    11101 gaagcgaata attcttatgt tgagtcttat acctattcag atattttgac ggaaaaaaca
    11161 ctgattcgtt attttgattg aaaaatcaat gcccatttag ggctttttct ttacactttg
    11221 ttgacagctg tgtaaagata tgaatcaatt tgaagccttg aagaacttat tagcaaatga
    11281 atgaagcccg gactaataat agggactagc tttcttgaaa agcagttact ctgagactct
    11341 cggtattaga tatcaaaaca taatatgcta ttttcaaaga atttcctatc ggtattaaaa
    11401 agccttgttt actcgggaag tgttgtgtaa aagcttgttt gccatatgat taacatcatc
    11461 tttgagctta cagctaacca tttttgatga tatgatatta aaaatgtaaa aaaaacttga
    11521 atcaatacct ttttcatgtt acaattagtt ttgtgtgaaa taacagcaga aaaatatgaa
    11581 gctcgtcaac aggcggttaa ctaaattgag taacctttgc tgtttaggcg aaaacctcct
    11641 gcacgaatca ggatttttca aacagttatt tcctcgttat attttttaga ggaggacatg
    11701 atacatgtca cgttatactg gtccatcatg gaaacaatca cgtcgtcttg gcttgtcatt
    11761 gacaggcaca ggtaaggaat tggcacgtcg taactacgta cctggtcagc atggccctaa
    11821 caaccgtagc aagctttcag aatatggctt gcaacttgct gagaagcaaa agcttcgctt
    11881 ttcatatggt atgggggaaa aacaattccg taacctattc gtacaagcta caaaaatcaa
    11941 agaaggaact cttggtttca acttcatgct tcttttagag cgtcgtcttg acaatgtggt
    12001 ttaccgctta ggtcttgcaa ctactcgtcg tcaagcacgt cagtttgtta accatggtca
    12061 tattcttgtt gatggtaagc gtgttgatat cccatcattc cgcgttgaga ttggccaagt
    12121 catctctgtt cgtgaaaaat caatgaaggt tcctgcaatc cttgaggcag ttgaagcaac
    12181 tcttggacgt ccagcttttg tttcatttga cgctgaaaag cttgaaggat cattaactcg
    12241 cctcccagag cgcgacgaaa ttaacccaga aatcaatgaa gcacttgtcg ttgaattcta
    12301 caacaaaatg ctttaagata agactttata ttataagaag cccacaacag tgggcttttt
    12361 tggttgagcg gttagctgat ttatgtaccg accccaaagg ttagaccaaa agtctaacga
    12421 ttggaggtcg gtattgttag gcataaagat cattataaac tcagtaagaa atagtttaca
    12481 aagttgtttt ttggtactgg atttgacatc attagtgcag gactatgttt tagatagcat
    12541 ttttaagacg aaacgagtca tttcctgagg ggattctttt tttcctttag caatccagct
    12601 ttggcagaca ccgaaaaagg catgtgctag gtagatgctt cgatattcct tttcggttgg
    12661 ggacaagatg tccttactga acttgtcctg aagatcggta gtgatcaaca gacgaacctt
    12721 gttaatgata aagctttgga tttctcgggt accattggag gatagcagag cagatagtag
    12781 ttgctctcgc ttgagaaatt caaatacttc taaaaaagca tgctccttgt tttggtattc
    12841 tttttcaaaa atgtattcta atttgtgaaa aaaggtttgt tgatagtaat caatcatctc
    12901 atatttgtct ttatagtgag tataaaagct agaacgacta atgcctgcca ttttagcaag
    12961 ctgaacggtt gttacatcat cgaagctttc ggtttttagt aagctcacca ttgcattaag
    13021 aatggccttc ttggtttgct gcttgcggct atccatcatt atctcctttt gaacacttgt
    13081 agacattatg tctaaaaaat ttattttttc cttgtaaaat gtcactttat ttgtataata
    13141 tattttatca taatttttga acagtatgtc tatttggaga aaaaataatg ctagaaggat
    13201 taaaagcaat aatcaaaaat cgtaagctag tagtgacaat gattggggtt gctctagtac
    13261 cagctctcta taatttgtcc tttttagggt ccatgtggga tccttatggt cgggttgatc
    13321 agttgcctgt agcagttgtg aatcaggata agcctgctta cttgaataac aagagactga
    13381 ctattggtaa cgatatggta gacaatatgt ctaaaaataa ggaattggat tatcattttg
    13441 tggctgcaga taccgcacaa aagggcttgg aaaagggtcg ttattatatg acgattacgt
    13501 tgccaaagga tttgtcacaa aaggccacta cgctattaga tcagcagcca gagaagctga
    13561 ttgttagcta tcaaactagt aagggccata gctttatcgc ttctaaaatg ggtgaatctg
    13621 ctatgaatca cttgagagag gctgtttcta aaaatataag gaagacctat atcacctccg
    13681 tttttaagag catgcatcag ctccaatctg gtctaaagga agcttcaaat ggcggtcagc
    13741 aattagccgc tggcttagta attgctaggg caagcagtca gctaatgtca aggcatttga
    13801 acaccttgtc tgaatcaagt gctcgcttgt ctcaaggagc gggtaatcta tctagtggta
    13861 tagctgccta tacagccggt gttggtcagc ttgataccgc gggcttagga cagctagcag
    13921 ctgatatgcc agcgtatcta gatggtgttt ctcggttatc caagggtgct aatcagttaa
    13981 atgctggctt gacccaattg gctctaggaa gtgatctgtc tcaagacaaa caagctaata
    14041 ttcaagcttt aatggctagc ctaccaaagc ttaatcaggc tatccagcag ctaaagacca
    14101 atctttcctt gtctttggca ccaaatgtgg actcaggagc cattgctaag catttagccg
    14161 atatgacgcg tttagtgcag gagcttgtgg tagatgatac tgctgacaag aacaatcagc
    14221 tagccgctct acaagctaca gctacctatc aaggtctcaa ctctgagcag caggaggagc
    14281 tgagctcagc tatttccaat acttcaacta aagtaacaat atcagcaaag gctatgttga
    14341 catcactgca agccatgtct gaggagctag aggctatgtc aacaagtgct ggtgtagctg
    14401 atcaactgag ggactttaaa gcacttgtta atcagctggc ttatcaagct gatcaaatcc
    14461 tacctagcac aggcaaggca ttgtcagagc tttcaactgg tttaagggct gttcactcag
    14521 cgacaacagc ccagctctta tcaggtagtc aagctcttgc tggcggcttt aatcaattga
    14581 cagctaagaa tgaagctctt acagcaggcc tgtctactct tgctacaggg gcaacagctc
    14641 ttaaccatca atccagtcaa ttattagcag gtggacagca gcttacagta ggcgctaatc
    14701 agctagcttt tggagccaat cagctctcct ctggcagctc tcagttgaca gatggcttga
    14761 caactctgtc aacaggtctg tcaagcttaa cgacctcact atcaaaagct tctgaccagc
    14821 tttcaatggc ttgggtagag gaccagaatg ctgatatggt atctgatcca gtagcgttat
    14881 cagagaagga caaggataag gttaggacca atggtattgg catggctcct tatatgattg
    14941 ctgtgtctct aatggtagtt gccttgtcta caaatattat ttttgcagag gccttatctg
    15001 gtaagccgat taaagataga tgggattggg caaagcaaaa attactgatc aatggcatga
    15061 tttcgaccgt tggctctgtt attctttacg ctgcacttca actgctgggc tttgaagcta
    15121 atgacggtat caagacctta ggctttatta tgctgagtgg atgggccttg atggctttag
    15181 tgactgcatt ggtcagctgg gatgctcgat atggtgcctt tgcttcgtta attatgctgt
    15241 tgctacaggt tggtgctgcg ggtggttctt atcctattga gttgagtggt cagatcttcc
    15301 agattctcca tccttatctt ccaatgtctt atattgtctc tggccttcgt cagacaatat
    15361 cattaactgc ccagataggt ttagagacga gtgtattagt tggctttttg ttaagcttta
    15421 tggctatagg agtgctgatt tatcgtccaa aggacaagca atcgtcctag ataatagctg
    15481 agataacagg ttatcgttaa acagtagata taataaaaaa gcttctagaa attgtggttt
    15541 aagctctttc tagaagcttt ttttatggtt ggtttagctt acggagataa gaccattatt
    15601 attggaaatg gtaagctgtg ctttaaaggg tgtttgacga cctgcttctt gactaatcgt
    15661 tacaaatcca ttattatttg aagcctttac gtcatagtag atgaggtttt ctctaggaca
    15721 attgatgtca atgattccat tcttattgat gatagtgatg tcattggaaa aggacagctg
    15781 ctgccctatg atattaccgt ttttgttttc aatgaaggtt tctgttagct gacttgcttc
    15841 taatctgatg tttccattgt tattgttcag ctggcaattt attagggtgc tattgtcaca
    15901 gctgaggtta gcatttttgg cttgacattt actagactgg atattgcaat gctctaaaat
    15961 aatgttccca tttttgctgc ttaggttgac agtgctatct gataaatgac tgatagaaat
    16021 cgttccattg taagtgttag agacaatgct atcacaatgt atatgcctta tggtgacatc
    16081 gttgttgtca ctttctccag agattttttt caggtggtgg ttgacaggta gtgtcaaggt
    16141 aatgggttga tattttgcaa gccagcggtc taggaaatga aagccatact gtattgtttg
    16201 tactgctgag tcttcaatga tattgagcat gccgtcacta tcttggctta ttgtgatgcg
    16261 attatcatcg tatgaaatag tagggtaagg aatgtcagca gtttcaatgg ttaaatcatg
    16321 gttaagcaga ctatagcgaa tgtcaactat tggctcaagc ttttgtgagc ttgcttctga
    16381 ctttgttttg ttgtcaactt cccaattcgt ccagtcatct tcgtctgttt tttcggggag
    16441 atctaaggct tttaatagct ccttggcaat gtcctctgga tttcccagtt ctttaagaat
    16501 agcttgttca tggtcaggac cagcctcgtc aaaatactct gtaaaatggt caatgatttc
    16561 ttggtaatcc ttttgaggta aatggttgat ctgctgcttt agcttgtcta gaaaatcttg
    16621 tttagtcatt atgatatcct cccttgatta atgaattgat aggtcgcttt gattgacagt
    16681 attggctatg tcagagtgaa atgaagtagc tcctgttgct gcgtctgtgt taagcttggc
    16741 gtttgaaaaa cgagagctga gcttgatgtt gcctcttgtt gtgacatgat aagcaatatc
    16801 tcttggattt gctaatgtgg tattgatatt aatatcgccg ccattaattg tgtttttctc
    16861 cttgattgtg acatgattta tagcaagctc ggaggggtct gtatagtcat agtcgttttc
    16921 ttcttttgta tcagctacag tgatagaaga gtctttgata ctgccgtcgt taagttctag
    16981 ctgacttgag ttctcagcag cttcataata atctgcttta ggtaattttc gtaggtattt
    17041 gtctagctct gctaggtatt catctcttgt catgccttaa tctcccttca ataatgccat
    17101 ctagggtggc cttgtagctt tgccattctt cctttaagaa aatcagctgc ttttcgcctt
    17161 tggctgtaat ggtgtaatag ttacgcttgc gaccttgatg ttcctgacta taggtagtta
    17221 aatagtctga tttctctagc ttttttaaaa tagggtatag ggttgattcc ctgatattag
    17281 cgacaagctt aatggtttgg ctgatatcat aaccatagga atcatgcttg tcgacaatag
    17341 ataaaatcaa aaattcaatc aaggtagcag atactggaaa atacatctgg ttactccctt
    17401 cctgcctcg
//
LOCUS       DARYYD010000041        17276 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.041, whole genome shotgun sequence.
ACCESSION   DARYYD010000041 DARYYD010000000
VERSION     DARYYD010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17276
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.041"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(216..1187)
                     /locus_tag="TV188_001406"
     CDS             complement(216..1187)
                     /locus_tag="TV188_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEL1534750.1"
                     /translation="MTYQKKLIAASMALASVFMLQTVHAAANNVQQVIDETYVQPDYV
                     LGYSLSAEQREQTLALLHYNSASDNKLSTLNTTAYASIMNVADDPSLQLYSSVRIQKL
                     GAKETLKVTIVTPENITKVTQDMYRNAAVTLGIEHANITVAAPIPVTGESALAGIYYS
                     LEKNGAKVPEENKKLAQEELSTLSNINTENAGKTGYDADKLNVALTDIKAAVAKAGEG
                     VNEEKVRQIVTETLDHYGLTKAVTPDQINLIINFALNLSNSGVISNENFTKTLNALKD
                     SIVEKAGSTFKNINVNFDATEALKTGQGILQQIIDFFRGLIDSLMGN"
     gene            complement(1500..1940)
                     /locus_tag="TV188_001407"
     CDS             complement(1500..1940)
                     /locus_tag="TV188_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1534751.1"
                     /translation="MTKKAYLSLFTILLLFPLSACDFKAQDSTGKKLKSSHQLEKRCK
                     ALKKETDKSPNEVSKEEGIAAEQIIVSISDDGFVTSHGDHYHFYNGEVPYDSLFSSEL
                     LPPKDYQFDQKDVINEVKNGYVIKTDDHYYFYLKDNNHQENLRS"
     gene            complement(1937..2872)
                     /locus_tag="TV188_001408"
     CDS             complement(1937..2872)
                     /locus_tag="TV188_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1534752.1"
                     /translation="MIRGFKKTIVAVGLLAVLLGLSACHQSSSSRKAGLVIKTSFYPI
                     YAMTKEICGDLNDVQVIAQNTSIHSYEPSPTVVAKVYDGDVFIYHSKILEAWAADLAP
                     QLEKKGLAVMEGTSHLTLDKVQGLEHFTIKKGMNTDALYDPHTWTDPILASQEAEQIA
                     ALLSQKDPAHKAVYLQNAKRFKAKAQKLVKTYKEKFESLGRKTFVTQHTAFSYLAKRF
                     DLKQLGIAGISPEQEPSPRQLAQIDRFIKKYDVKTIFVEENASDKLAKTLAQSNGVAI
                     DILSPLEVVPADQKTYLEHLKMNLETLYRVLESET"
     gene            complement(3310..3723)
                     /locus_tag="TV188_001409"
     CDS             complement(3310..3723)
                     /locus_tag="TV188_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEL1534753.1"
                     /translation="MELKAIHHIAIIVSDYEVSKDFYVNKLGFEIIRENHRPDRHDYK
                     LDLKCGAIELEIFGNKKTDPAYQAPPKRIGRPEYDKEACGLRHLAFHVKPIEAYIEQL
                     MAKGIAVEPLRYDDYTGKKMTFFFDPDGLPLELHE"
     gene            complement(3821..4576)
                     /locus_tag="TV188_001410"
     CDS             complement(3821..4576)
                     /locus_tag="TV188_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HEL1534754.1"
                     /translation="MAKRTHRRRQKRRKMSFARGILVVLLLIIGLALLFNKPIRNTLI
                     AWNSNKYQVTKVSKKTIKKNKEAKSSFDFQAVQPVSTESVLQAQMDAQQLPVIGGIAI
                     PELGINLPIFKGLGNTELIYGAGTMKEDQVMGGENNYSLASHHIFGLTGSSEMLFSPL
                     ERAKEGMSIYLTDKERIYEYEINAVFTVTPERIDVINDTPGLKEVTLVTCTDYEATER
                     IIVKGAIKNEYEFNKAPDDVLKAFNHSYNQMST"
     gene            complement(4581..7076)
                     /gene="gyrA"
                     /locus_tag="TV188_001411"
     CDS             complement(4581..7076)
                     /gene="gyrA"
                     /locus_tag="TV188_001411"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEL1534755.1"
                     /translation="MQDKHLVDVNLTSEMKTSFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRHMLVD
                     GHGNFGSMDGDGAAAQRYTEARMSKIALELLKDINKNTVDFQDNYDGNEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLAEAIDAVKMVMENPDCTTRDLMEVLPGPDFPTG
                     ALVMGRSGIHKAYETGKGSIVLRSRTEIETTSTGRERIVVTEFPYGINKTKVHEHIVR
                     LAQEKRIEGITAVRDESSRQGVRFVIEVRRDASANVILNNLFKLTSLQTNFSFNMLAI
                     EGGIPKILSLRQIIDNYILHQKDVITRRTQFDKDKAEARAHILEGLLIALDHLDEVIA
                     IIRNSETDIIAQAELMSRFDLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILARPERIEAIIKEEMEEIKRKYANPRRTELMIGEVLSLEDEDLIEEEDVLITLS
                     NNGYIKRLAQDEFRSQKRGGRGVQGTGVNDDDFVRELVSTSTHDTLLFFTNFGRVYRL
                     KAYEIPEYGRAAKGLPVINLLKLDDGETIQTIINAKKEDILDKYFFFTTKQGIVKRTE
                     VSEFSNIRQNGLRALNLKEGDELINVLLTNGQEDIIIGTRSGYSVRFNEATIRGMGRS
                     ATGVRGVKLREEDWVVGASRINDKQEVLVITENGYGKRTSAAEYPTKGRGGKGIKTAN
                     ITAKNGQLAGLMTVDGSEDIMVITTKGVIIRTNVSSISQTGRSTLGVKVMRLDTDSKI
                     VTFTLVQAEDNDPTAIAQTDTALTEAPINSSKE"
     gene            7268..8251
                     /locus_tag="TV188_001412"
     CDS             7268..8251
                     /locus_tag="TV188_001412"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEL1534756.1"
                     /translation="MTATKQHKKVILVGDGAVGSSYAFALVTQNIAQELGIIDIFKEK
                     TQGDAEDLSHALAFTSPKKIYAADYADCHDADLVVLTAGAPQKPGETRLDLVEKNLRI
                     NKEVVTQIVASGFKGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFRQAL
                     AAKIGVDARSVHAYIMGEHGDSEFAVWSHANVAGVGLYDWLQANRDVDEQGLVDLFIS
                     VRDAAYSIINKKGATFYGIAVALARITKAILDDENAVLPLSVFQEGQYEGVEDCYIGQ
                     PAIVGAYGIVRPVNIPLNDAELQKMQASANQLKTIIDEAFSKEEFASAAKN"
     gene            complement(8456..9823)
                     /locus_tag="TV188_001413"
     CDS             complement(8456..9823)
                     /locus_tag="TV188_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEL1534757.1"
                     /translation="MSKIVVIGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGC
                     GMALWIGEQISGPEGLFYSNKEELESLGAKVYMESPVQSIDYDAKTVTALVDGKEHVE
                     SYDKLIFATGSQPILPPIKGAEIKEGSLEFEATLENLQFVKLYQNSADVISKLENKDI
                     KRVAVVGAGYIGVELAEAFQRKGKEVILIDVADTCLAGYYDRDLTDVMSKNLEEHGIQ
                     LAFGETVKEVAGDGKVEKLITDKNEYDVDMVILAVGFRPNTALGAGKIELFRNGAFLV
                     NKHQETSIPGIYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNACGTALEGIGV
                     QGSNGISIYGLHMVSTGLTLEKAKCLGFDAAVTEYTDNQKPEFIEHGNFQVTIKIVYD
                     KESRRILGAQMASHEDISMGIHMFSLAIQEGVTIEKLALTDIFFLPHFNKPYNYITMA
                     ALGAE"
     gene            complement(10073..10675)
                     /locus_tag="TV188_001414"
     CDS             complement(10073..10675)
                     /locus_tag="TV188_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HEL1534758.1"
                     /translation="MFRVLKRILGLAVLIFCLYEAVTIHKNVHRVLQYKPTVERILAE
                     NGNKADVDLVLAMIYTETKGGEADVMQSSESSSGIRDSITDSQSSIEYGVRLLSHNLA
                     LAEKAGVDPWTAVQAYNFGTAYIDYVAKNGGQHTIELATNYSRTVVAPSLGNTTGKTY
                     FYYHPLALLSGGKLYCNGGNIYYAQEVHVNLYLIELMSLF"
     gene            complement(10676..11653)
                     /locus_tag="TV188_001415"
     CDS             complement(10676..11653)
                     /locus_tag="TV188_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEL1534759.1"
                     /translation="MLDIYIKGIVIHQFTPNDTELILSDALVAITPRIDEYFRKKLAK
                     VFSDDAKRGQLEADHAFFTTIGTELLETSVTIAKLWKEEFVASEHQKTNDLVFIQFDK
                     EGVPYLAFLRIALKEHFAHLSDDHENPITITQNNLPSPTQAPDEALVINRQTGYYYLI
                     EKRMKHNGSFAHYFSEKLLKVTPEQSVKKSIQMLEQTAQKVAENFNQDDFAFQSKMKV
                     ALAKNLEEETALSPEKLADQLFDQNLTARLTFVDQVKEMIPEPIQVSDIDHSRQLKKL
                     ETQKLSLSNGIELLVPNAVYQDAESVEFILNDNGTYSILIKNIEDIKNN"
     gene            complement(11656..12915)
                     /locus_tag="TV188_001416"
     CDS             complement(11656..12915)
                     /locus_tag="TV188_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEL1534760.1"
                     /translation="MMFNNENYKDYDQELWEAIQAEEDRQEHNIELIASENMVSKAVM
                     QAQGSVLTNKYAEGYPSKRYYGGTEYVDIVESLAIERAKKLFGAAYANVQPHSGSQAN
                     AAAYMALINAGDTVLGMDLAAGGHLTHGSPVNFSGKTYQFVGYTVDKETEKLDYAAIL
                     KQAKAVQPKLIVAGASAYSRQIDFEQFRFIADQVGSYLMVDMAHIAGLVAAGLHQNPV
                     PYAHIVTSTTHKTLRGPRGGLLLTNDEAISRKMNAAIFPGLQGGPLEHVIAAKAVAFK
                     EALDPAFTDYARAVIANTAAMAEVFAKDDRFRLISGGTDNHLFLVDVTKVIENGKLAQ
                     ALLDEVNITLNKNAIPFETLSPFKTSGIRIGCAAITSRGMGVDESRTIAHLIIKALVN
                     HQQPEILEEVRYEVRRLTDAFPLYKKN"
     gene            complement(12927..13358)
                     /locus_tag="TV188_001417"
     CDS             complement(12927..13358)
                     /locus_tag="TV188_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1534761.1"
                     /translation="MLRPLDQTDCQAICDINDQSLGYKVSLELTKSQLEKLRSDKHHY
                     LLGYADTKTNLLLGYLHAECYESLYSEKGFNILALAVRLDHQGRGIGRRLLAALEEKA
                     KQEKVSFIRLNSASHRTEAHAFYRKLSYVDDKTQLRFMKLL"
     gene            complement(13372..13965)
                     /locus_tag="TV188_001418"
     CDS             complement(13372..13965)
                     /locus_tag="TV188_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEL1534762.1"
                     /translation="MITHLIETIKAGGALILPTETVYGLFAQALNEEAVNAVYRLKKR
                     PRDKAMNLNVADFESILAFSKQQPAYLNKLYEAFLPGPLTIILKANAQTPYWINSGLK
                     TVGFRLPSHPLTAKIIRATGPLIGPSANLSGSKSGKCFNDIVKAFDGKVDGYADDAYL
                     TGKDSTILDLSSPKVSILRQGAITKEQLLAKVPELPF"
     gene            complement(13937..14785)
                     /gene="prmC"
                     /locus_tag="TV188_001419"
     CDS             complement(13937..14785)
                     /gene="prmC"
                     /locus_tag="TV188_001419"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEL1534763.1"
                     /translation="MNYAKQLRAYEDRLENIGEDRENLAYVFKELKQWTSLDFLLHQN
                     QEVTSEDQALLERIFLALSQHVSPQYITGRAYFRDLVLAVDSRVLIPRPETEELVELI
                     LKENDATRKSVLDIGTGSGAIAIALKKARPNWQVTASDISADALSLAYSNALDHHVEI
                     AFEQSDLFSKLSGQFDIIVSNPPYIAYEDKDEVGLNVYQSEPHLALFAAENGFSIYRR
                     IIEQASAYLTTSGKLYFEIGYKQGEGLKRLLSKRFPQKRIRVLKDMLGKERMVVVDDN
                     TFDRDN"
     gene            complement(14782..15864)
                     /gene="prfA"
                     /locus_tag="TV188_001420"
     CDS             complement(14782..15864)
                     /gene="prfA"
                     /locus_tag="TV188_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEL1534764.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPEVVSDTKRFMALSKEEASTR
                     ETVAAYRQYKAIIQSIDDAEEMIKEAGGDPDIEEMAKEELKEAKSAKEAYEDKLKLLL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLAMYQKFAESQGWRFEVMEASYNGVGG
                     IKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRIDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNRDKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEIVDALVLYDQTQKLESLNNQ"
     gene            complement(15906..16475)
                     /locus_tag="TV188_001421"
     CDS             complement(15906..16475)
                     /locus_tag="TV188_001421"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEL1534765.1"
                     /translation="MAQLYYKYGTMNSGKTIEILKVAHNYEEQGKPVVIMTSALDTRD
                     GFGIVSSRIGMRREAVPISNDMDIFAFIAELQEKPYCVLIDECQFLSKQNVYDLARVV
                     DELNVPVMAFGLKNDFQNELFEGSKYLLLLADKIDEIKTICQYCSKKATMVLRTEHGK
                     PVYEGAQIQIGGNETYIPVCRKHYFHPPI"
     gene            16662..16847
                     /locus_tag="TV188_001422"
     CDS             16662..16847
                     /locus_tag="TV188_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEL1534766.1"
                     /translation="MPFVTIDLFEGRSQEQKIALAREVTEVVSRIAQAPKEAIHVVIN
                     DMPEGTYFPHGEMKTKA"
     gene            16902..>17276
                     /locus_tag="TV188_001423"
     CDS             16902..>17276
                     /locus_tag="TV188_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEL1534767.1"
                     /translation="MIATDQIKMMGTIIDICIDSSKAKQQAATIRELLTLYNHRFSAS
                     DDSSELMAINHMAGIQPVRVHSDLFDLISIGKEHSLAYPSNLNITLGPLVQSWRIGFS
                     DAKLPDEATIDRRLRLTNPNHII"
BASE COUNT         4871 a         3774 c         3285 g         5346 t
ORIGIN      
        1 tcatctttaa gtatctaaat atctgatctt gaaatagatc tgcttctact taatttattc
       61 gaaaaatagt ttgaaaaata attgcttttt ttgattttca atttgattat ttttagctgc
      121 tcaaatgaat aatcgatttc ggtttaaata agtttaaaaa ataggactaa ttcctaatga
      181 aatcaggaat tagtcctact acttttatct atttatcagt tacccattag gctgtcaatc
      241 aatcctctaa agaaatcaat aatttgctga aggattccct gtccagtctt taaggcttca
      301 gtagcatcaa agttcacgtt gatattttta aaggtagatc cggccttttc aacaatacta
      361 tcctttaaag cattcagcgt tttggtgaag ttttcattgg aaatcacgcc actatttgag
      421 aggttaagcg cgaaattgat aataaggtta atctgatcag gtgttactgc cttggttaac
      481 ccataatgat ctaaggtttc tgttacaatt tggcgcacct tttcctcatt aaccccttct
      541 ccagcctttg cgacagcagc tttaatatca gtaagcgcaa catttagctt atctgcatca
      601 tagcctgttt tacctgcatt ttcggtattg atattagata gggttgatag ctcctcttgt
      661 gccagcttct tgttttcctc tgggactttg gcaccatttt tttcgagtga ataataaata
      721 ccggctaaag ctgattctcc agtaactggg attggtgcag ctacagtaat attggcatgc
      781 tcaatgccca aggtcacagc ggcgttacga tacatatctt gcgtcacctt agtgatattt
      841 tcaggtgtta caatagttac cttaagcgtt tctttagctc ccagcttttg aatcctaact
      901 gaggaataaa gctgtaggct cggatcatct gctacattca tgatactagc ataggcagtt
      961 gtatttaggg tgcttaattt gttatcagaa gcactattgt agtgaagcaa ggccaaggtt
     1021 tgctctcttt gctcagcaga cagtgaatag cctaaaacgt aatcaggctg aacataggtt
     1081 tcatcaatta cctgttgaac attattagct gcagcgtgta ctgtttgaag cataaatacc
     1141 gaagccaaag ccatactggc tgctattaat ttcttttgat aagtcatttt tctacctctt
     1201 ttgtgttata aattttcctt tacgagaatc ctccagaaaa gacgattaaa gccaaagtat
     1261 ctaggtgcct agtaagaccg ttttacttag ctctgcaaag ggcaatattc ctagtctttt
     1321 tcaaaatcta acgcctctat tgtagcattt ttacctcaat aagacgatta aaaagctgaa
     1381 acaaagcata gctagaatgg ccaagcacta tttttacaac aaaaaaacta gtgcataatg
     1441 gcagcttaga tgtagctact atcactagtc caatgattat cttatgcagc aaccagtctt
     1501 tatgatctga ggttttcttg atggttattg tcctttaaat agaaataata atgatcatca
     1561 gttttgatga catagccatt tttaacctca ttaatcacgt ccttttgatc aaactggtag
     1621 tccttaggcg gtaataactc tgaggaaaaa aggctatcat aaggcacctc accattgtaa
     1681 aaatggtaat ggtcaccatg agaggtaaca aaaccatcat ccgagataga cacaataatt
     1741 tgctctgctg ctatcccctc ttccttgcta acttcattag gacttttgtc agtctctttc
     1801 tttaaggctt tgcacctttt ttccaattga tgagatgatt ttagcttctt gcctgtgcta
     1861 tcttgggctt taaagtcaca agcggacaaa ggaaataata gtaagatagt gaataacgat
     1921 aaataagctt ttttggtcat gtttcactct ccaatacacg atatagtgtt tctaaattca
     1981 tttttaaatg ctctagataa gttttttgat cagctggaac cacctcaagc gggcttagga
     2041 tatcaattgc tacaccgtta ctttgagcca aggttttggc tagcttatct gaagcatttt
     2101 cttcgacgaa aatcgtcttc acatcatatt ttttgataaa gcggtcaatt tgagctaatt
     2161 ggcgaggact aggctcttgc tcaggagata tccctgcaat tcccaattgc tttagatcaa
     2221 atctcttagc taggtaggaa aaggctgtat gctgtgtcac aaaggttttc ctacctagag
     2281 attcaaactt ttccttatag gtcttcacta atttttgagc cttagcctta aaacgcttag
     2341 cattttgcaa ataaactgcc ttgtgagcag gatctttttg actcaataaa gctgcaatct
     2401 gctctgcctc ttgactagct aagataggat cagtccaagt gtgaggatca tacaaggcat
     2461 cggtattcat tccttttttt atggtgaagt gctccaagcc ttgaaccttg tctaatgtta
     2521 gatgtgatgt cccctccatg actgctaatc cctttttttc cagctgtggt gccaaatccg
     2581 cagcccaagc ttctaatatc ttggaatggt aaataaagac atctccatcg taaaccttag
     2641 caacaactgt cggacttggc tcatacgagt gtatgctagt gttttgggca atgacctgaa
     2701 catcatttaa atccccgcaa atctcctttg tcatagcata aataggataa aagcttgttt
     2761 ttatgaccaa accggccttc ctactgctag agctctgatg acaggctgat agacccaaaa
     2821 gtactgctaa tagtcctact gcgacaattg ttttcttgaa tcctctaatc atatctactc
     2881 tcttaactag ttaatgacct aaaaaggata ccatgattta actgaaatgt caatatttta
     2941 tcattttagc gcacgacgta cacgcatgaa gaaaatgcat gtaagccttt tttagcccca
     3001 tgcatttttt aatctatttc tagcgttttg acattgcaat atcatcagtt tgtcaatttc
     3061 aatgtgatga cttcatcaca ttttgctaaa aaggccatag tgatgataaa aaaccgctac
     3121 cagaaagcgt aaatgtcttc ttgcttttgt cgtgatttta gtgaaccgcc taccaactga
     3181 actgatgctg gcttaaccat ttcctggcca ccatcaaaag cctgcctctc aattaacaag
     3241 cttactcaag gaagaggtga ctgagccatg catccgtctt agttatgact aacagcttat
     3301 cttggcattt cattcatgta attccagtgg caggccatca ggatcaaaaa agaaggtcat
     3361 cttcttacca gtataatcat catacctaag aggctcgaca gcaatgccct tagccattaa
     3421 ttgttcaata taagcttcaa taggcttaac atgaaaagct aaatgacgaa gcccacaggc
     3481 ctctttgtca tattcgggcc taccgatacg cttaggcggt gcctgataag ctggatcagt
     3541 ctttttattg ccaaaaatct ctaattcaat ggctccacat tttaaatcca atttgtaatc
     3601 atgtctatca ggccggtgat tttcacgaat aatctcaaag ccaagcttat tgacataaaa
     3661 atccttagag acctcataat ccgaaacaat gatagcaata tgatgaatag ccttaagctc
     3721 catatgattt agttccttta ttaaataaaa aaagtgaaac aaagcaatgc caagattact
     3781 ttgtttcacc cctcgtagcg acccctcgcc tagattaggc ttaggttgac atctgattgt
     3841 aagagtgatt aaaggccttc aaaacatcgt caggtgcttt gttaaactca tactcgtttt
     3901 tgattgctcc tttgacaatg attcgctctg ttgcctcata atccgtacag gtgaccaagg
     3961 ttacctcctt tagccctggt gtgtcattga taacatctat tctctcaggt gtgaccgtaa
     4021 agacggcatt gatctcgtac tcgtaaatac gctccttatc tgtaaggtaa atagacatcc
     4081 cttcttttgc tctttcaagc ggtgagaata acatttcaga agagcctgtt agtccaaaaa
     4141 tatgatgact ggctaaggag taattgtttt ctcctcccat aacctggtcc tctttcatgg
     4201 taccagcacc gtatataagc tctgtgttgc caagcccttt aaagattggt aggttaatac
     4261 caagctctgg tatggcaata cctcctatta ctggaagctg ctgggcgtcc atttgagcct
     4321 gtaagacact ttcggtgcta actggctgaa ctgcttgaaa atcaaagctt gactttgctt
     4381 ccttattctt tttaatcgtc ttttttgaaa cctttgtaac ttgatattta ttagaattcc
     4441 aagcaatcag ggtgtttcta atgggcttgt taaataacaa ggctaagcct atgattaaca
     4501 ataagacgac tagaatacct ctagcaaagg acatctttct tcgtttttgt cttctcctgt
     4561 gggttctttt tgccattcat ttactccttg ctagaattta ttggtgcttc tgttaaagct
     4621 gtatcagtct gagcgattgc tgttggatcg ttgtcttcag cctgtaccaa ggtaaaggta
     4681 acaatcttag aatctgtatc tagcctcata accttaacac caagtgttga acggccagtc
     4741 tgagaaatac ttgaaacatt ggtacgaata atcacaccct tcgttgtgat caccataata
     4801 tcctcactgc catcaacagt catcaggcca gccaactggc cattttttgc ggtgatatta
     4861 gctgttttga ttccttttcc acctcgaccc ttagttgggt attcggctgc actggtacgc
     4921 ttaccatagc cattttcggt gatgactaag acctcttgct tgtcattgat acgagaagct
     4981 ccgacaaccc aatcttcctc acgaagcttg acaccacgaa cacccgtagc gctacgcccc
     5041 atgcctcgaa tggtagcttc attaaagcga acagaataac ctgatcttgt tccaatgata
     5101 atatcttcct gaccatttgt caagagaaca ttaatcagct catctccttc cttgagatta
     5161 agggctcgta gaccattctg acgaatattg ctaaactctg atacctcagt tcgtttgaca
     5221 atcccttgct ttgttgtaaa gaagaaatat ttatcaagaa tgtcttcttt tttagcattg
     5281 ataattgttt gaatggtttc accatcatct agctttagta gattgataac aggaagtcct
     5341 tttgcagcac gtccatattc tggaatctca taggccttta agcgatagac gcgcccaaaa
     5401 ttggtaaaga aaagcaatgt gtcatgtgta cttgttgaga caagctcacg aacaaagtca
     5461 tcgtcattga cacctgttcc ctgtacacca cgaccaccac gcttttgaga tcgaaactcg
     5521 tcttgagcaa ggcgcttaat gtagccattg tttgataggg tgatcaaaac atcttcttcc
     5581 tcgatcaaat cctcatcttc taatgacaat acctcaccaa tcatcaattc tgtgcggcga
     5641 ggattagcgt acttgcgctt gatctcctcc atttcttcct tgatgatggc ttcgatacgc
     5701 tctggccttg ccaaaatatc tgccaaatct gcaatcaaag ccagtaggtc atcgtattct
     5761 gattgaattt tatcacgttc caagccggtc aaacggcgaa gacgcatgtc taaaatagcc
     5821 tgactttggc gttcagacaa gtcaaaacga gacatcaatt ctgcttgtgc gataatatct
     5881 gtctcgctat tgcggataat ggcaataacc tcatctagat ggtcaagagc gataagtaag
     5941 ccctctaaaa tgtgtgccct agcttctgcc ttgtccttgt caaattgagt cctgcgtgta
     6001 atgacgtcct tttgatgtag aatataatta tcaataatct gtctcagtga caagatttta
     6061 ggaatcccgc cttcaatggc tagcatattg aagctaaagt ttgtctggag acttgtcaat
     6121 ttgaataggt tatttaaaat cacattagca gatgcatcgc gacggacttc aatgacaaat
     6181 cgtacccctt gtcggcttga ttcgtcacga acagctgtaa tgccctcaat acgcttttct
     6241 tgggctaagc gaacaatatg ctcatggacc tttgttttat taatgccata agggaattct
     6301 gtgacgacaa tccgctcccg tcctgtacta gtggtttcaa tctcggtgcg tgaacgcaaa
     6361 acgattgatc ccttaccagt ctcataagcc ttatgaattc ctgaacgtcc catcaccaag
     6421 gcacctgtag gaaaatccgg ccctggaaga acctccatta aatctctggt agtgcagtca
     6481 ggattttcca tgaccatctt aacagcgtct atggcctcag ctaaattatg aggtggaata
     6541 ttggtagcca taccaactgc gattccggtg gcaccattga ccaataaatt ggggaagcga
     6601 gccggtaaga ctaagggttc tctttcatta ccatcgtagt tatcctgaaa gtcaacagta
     6661 tttttattaa tatcctttaa gagctctagc gcgattttgc tcatacgagc ctcagtataa
     6721 cgctgagccg cagcaccgtc accgtccata gaaccaaagt ttccatgacc atcgacaagc
     6781 atgtgacgat agctccacca ctgggccata cggaccatcg cttcatagat ggacgaatcc
     6841 ccatgtgggt ggtacttacc catgacatca ccggtaatac gagcagattt tttatgtggc
     6901 ttatcaggtg tgacgcctag ctcattcatg ccataaagga tacgacgatg aacaggcttt
     6961 aagccatctc gtacatctgg aagtgctctt gctacaataa cgctcatagc ataatcaatg
     7021 aaactcgttt tcatctcact tgtcagattg acgtcaacta aatgtttatc ttgcatttaa
     7081 ggaatgctcc ttttctagtc aatactcttt taattatacc ataaaatcct tattttttct
     7141 gattggaaac gctgtccgaa aacaattttc ataatttggt cgaatatcat gacaaagaca
     7201 ttaaaatgtg ttaaaataag atcgtatgag caatttgctc taactaaaat gaaggagatg
     7261 tttagaaatg actgcaacta aacaacataa aaaagtcatc ttggttggcg atggtgctgt
     7321 aggctcttct tatgcctttg cactagtaac ccaaaatatt gcccaagagc ttggtattat
     7381 tgatattttt aaagaaaaaa ctcaaggaga tgctgaggat ttaagccatg cgcttgcctt
     7441 tacctcccct aaaaagatct atgctgctga ttatgctgac tgtcacgatg ctgacctagt
     7501 tgttttaaca gctggcgctc ctcaaaagcc aggtgagact cgtcttgacc ttgttgagaa
     7561 aaatctacgt attaataaag aagtggttac tcaaattgtg gcctcaggct ttaagggaat
     7621 tttccttgtt gctgctaatc cggtggatat tttgacctat tcaacctgga aattctcagg
     7681 tttccctaag gaacgcgtta tcggttctgg aacatcactt gactcagcac gcttccgtca
     7741 ggcacttgct gccaaaattg gtgtagacgc acgttctgtt catgcctaca tcatgggtga
     7801 gcatggagat tcagaatttg ctgtttggtc acatgctaat gttgcagggg ttggattgta
     7861 cgactggctt caagctaatc gtgacgttga tgaacaaggc ttggtagacc tctttatctc
     7921 tgtacgtgac gcagcttact ctatcatcaa taaaaagggt gctaccttct atggtattgc
     7981 agtcgcccta gcacgtatta caaaagctat ccttgatgat gaaaatgcag ttcttccact
     8041 ttctgttttc caagaaggcc aatacgaagg cgttgaggat tgctatatcg gtcagcctgc
     8101 tattgttggt gcctatggta ttgttcgtcc agtcaatatc ccattgaatg acgctgagct
     8161 tcaaaaaatg caagcttcag caaaccaatt gaagactatt atcgacgaag ccttctctaa
     8221 agaagagttt gcgtctgctg ctaaaaacta attaaaaaat gaatgtgtta gatcttgctc
     8281 taacgttttg gaatcactac aaaaagccta atccaatcgg ataggctttt ttcatgcgtc
     8341 taacagcgag gtgcaagaca aagcacgctt tcattaagca tcgtgtgtgc tatgcttata
     8401 gtcttaagtc acaaaaaaga caaccagctt tatgagctgg ctgcttatta gcttgttatt
     8461 cagcaccaag tgctgccatt gtaatgtagt tatatggctt gttaaagtgc ggtaagaaga
     8521 aaatatcagt caaagctaat ttctcaatgg tcactccttc ttggatagca agtgagaaca
     8581 tatgaattcc cattgaaata tcttcatgtg aggccatttg agcacctaga atacgacgtg
     8641 attctttatc gtagacaatc ttaatggtta cttggaagtt accatgctcg ataaattctg
     8701 gtttttgatt gtcagtgtat tctgttactg ctgcatcaaa gccaaggcat tttgctttct
     8761 caagagttaa gccagttgat accatgtgca agccgtagat agagatacca tttgatccct
     8821 gcacaccaat accctcaaga gctgtgccac aagcgttatg agctgcgaca atccctgtac
     8881 gaacagcatt tgaagcaagg gcaatataat tggtatcgcg agttgcgttg tcatagatgg
     8941 ttgcacaatc accgattgca taaatccctg gaatagatgt ttcttggtgt ttgttaacaa
     9001 ggaaggcacc attacggaaa agctcaatct tgccagcacc aagagctgta tttggacgga
     9061 agccaactgc aaggataacc atatcaacat catattcatt cttatcagtg attagctttt
     9121 caaccttgcc atcaccagca acctctttga cagtttcccc aaaggccaac tgaataccat
     9181 gctcttctag gtttttagac atgacatctg tcaaatcacg atcatagtag cctgctagac
     9241 aagtatccgc aacatcaatc agaataacct ctttgccctt acgttggaag gcttctgcaa
     9301 gctctacacc aatgtagcct gcaccaacga ctgcaacgcg cttaatgtct ttgttttcta
     9361 atttcgaaat gacatctgct gaattttggt acaatttaac gaattgaaga ttttcaagtg
     9421 ttgcttcaaa ctctaatgag ccctctttga tttctgcacc tttaattggt ggcaagatag
     9481 gctgtgaacc agttgcaaaa attaatttgt catatgactc aacatgctct ttgccatcaa
     9541 caagggctgt cactgtttta gcatcgtagt caatagattg aactggtgat tccatgtaaa
     9601 ccttagcacc aagggactct agctcttcct tatttgagta gaataagccc tctgggccag
     9661 aaatttgttc gccaatccaa agtgccatac cacagcctaa gaatgaaata tttgagtttt
     9721 ggtcaaatac aacaatctca ttagcatcac catagtttgt taacatagtc ttgatacatg
     9781 ccgtacctgc gtggtttgca ccgataacaa cgattttact catatgatta tgttcctcat
     9841 ttcacaattt atattaggtc tctattataa cacagggaaa aagcgcttcc aactaaaatg
     9901 ctcatttttc ttgctttttt ataccgtttt ttagtcaata aataagacag cctatcattt
     9961 gttgaagggt cgtacaaaga ccggtttgct tcagttaagt caagacgaca ttcttattca
    10021 actattttcc caaattcatt acatgattaa gaccattttt tgtcgttaac ttctaaaaaa
    10081 gactcataag ctcaatcagg taaagattga catgtacctc ttgagcataa taaatattgc
    10141 cgccgttgca ataaagcttt ccaccagaga ggagggctaa ggggtggtaa taaaaatagg
    10201 tttttccagt agtatttcct aggctgggtg caacgacagt tctagaatag ttagtggcta
    10261 gttcaattgt atgctgaccg ccatttttag caacgtaatc aatataggcg gttccaaaat
    10321 tgtaagcttg aacagctgtc caagggtcta cgccggcttt ttctgctaaa gctaaattgt
    10381 gagatagcaa tctgacacca tactcaatgc tagattgact atcggtgatc gaatccctta
    10441 tgccagagct gctttcgctt gactgcataa cgtcagcttc tcctccctta gtttccgtgt
    10501 atatcatggc tagtaccaga tcgacgtctg ctttgttacc gttttctgct aaaatacgct
    10561 ctactgttgg cttgtattgt aggactctgt gcacattctt atgaatggta actgcttcgt
    10621 acaggcaaaa aatgaggacg gctaatccta agatacgctt taacactcta aacatttagt
    10681 tatttttgat atcctctata ttttttatca atatggaata ggttccgttg tcattcaaga
    10741 taaactctac tgactcagca tcttgataaa ctgcattagg gacaagaagc tcaattccat
    10801 ttgacagcga cagcttttgc gtctctagct tttttagctg tctagaatga tcaatatcac
    10861 tgacctgaat tggttcggga atcatttcct tgacctgatc cacaaaggtt aaccttgcag
    10921 tcaggttctg gtcaaataat tgatctgcta gcttttctgg agatagagct gtttcttctt
    10981 ctagattttt agccagtgct actttcatct ttgattgaaa agcaaagtca tcttggttaa
    11041 aattctcggc aaccttttga gcggtctgct caagcatttg aatagatttt ttgacagatt
    11101 gctcaggtgt tacctttagc agcttctcag aaaagtaatg agcaaagctt ccattgtgct
    11161 tcatgcgttt ttcgattaag tagtaatagc ctgtttgacg gttaatgacc aaggcttcat
    11221 caggtgcctg agtagggctt ggcaaattat tttgcgtgat cgtaatagga ttttcatgat
    11281 cgtctgatag atgggcaaaa tgctctttta gggcaatgcg taaaaaggcc agataaggca
    11341 ctccttcctt atcaaactga ataaaaacca aatcgtttgt cttttgatgt tcagaagcga
    11401 caaattcttc cttccaaagc ttggcaattg ttactgatgt ttccaaaagc tctgtaccga
    11461 ttgtggtaaa aaaagcatga tcagcttcta attgcccacg tttagcgtcg tcagaaaaaa
    11521 ccttggctaa ttttttgcga aaatactcat caattcttgg tgttatagct actaaagcat
    11581 ctgataagat cagctcggta tcgtttggtg tgaattggtg gatcacaatt ccttttatat
    11641 aaatatctag cattgttagt tcttcttgta taatgggaag gcgtcagtca atcggcgaac
    11701 ctcataacgg acctcttcaa ggatttcagg ctgctggtgg ttaaccaagg ccttgataat
    11761 taaatgagca atagtcctac tttcgtctac tcccattcca cgactggtaa tggcagcgca
    11821 gcctatgcga atgcctgatg ttttaaaggg agatagggtc tcaaaaggaa tagcattttt
    11881 gttaagggta atattaacct catcaagcaa ggcttgagca agcttgccat tttcaatcac
    11941 cttagtcaca tcaacaagga aaagatggtt atctgtaccg cctgagatca gacgaaaacg
    12001 atcatccttg gcaaaaacct ctgccattgc tgctgtattt gctataacag cccttgcata
    12061 gtctgtaaag gcaggatcaa gcgcctcctt aaacgcaaca gccttcgctg ctatgacatg
    12121 ctccaaaggc ccaccctgta gaccagggaa aatagctgca ttcattttcc ttgaaattgc
    12181 ttcatcattt gtcaaaagca ggccaccacg aggaccacga agggttttat gagtggttga
    12241 ggtcacaata tgagcataag gtactggatt ttgatgcaga cctgctgcaa ccaagcctgc
    12301 aatgtgtgcc atatccacca tcaaatagga tcccacctgg tctgcaataa aacgaaattg
    12361 ctcaaaatca atctgccgag aataggctga ggcacctgca acaatcaact taggctgaac
    12421 agccttagct tgctttagga tagctgcgta gtccagcttt tcagtttcct tatcgacagt
    12481 gtagccgaca aattgatagg tttttccaga aaaattgaca ggtgagccat gtgtcaagtg
    12541 acctccagct gccaaatcca taccaagcac agtgtcacca gcattaatca gtgccatata
    12601 agcagcagca ttggcctgac taccagaatg aggctgaacg ttggcatagg ctgcaccaaa
    12661 gagctttttg gcacgctcaa tagcaaggct ttcaacaata tcaacatact ctgtgccgcc
    12721 ataataacgc ttgcttggat agccctcagc gtatttgttg gtcaagacag agccttgtgc
    12781 ttgcataaca gcctttgaga ccatattttc agaagcaatt agctcaatat tatgctcttg
    12841 cctgtcctcc tcggcctgaa tagcctccca aagctcctga tcatagtctt tgtagttctc
    12901 gttgttaaac atcattattg tctcctctat aatagcttca taaatcgtaa ttgtgtctta
    12961 tcatctacat agctcagctt acggtaaaag gcatgtgcct cggtcctgtg actagcagaa
    13021 ttaagccgaa taaagcttac tttctcctgc ttagccttct cctctaaagc agctagtaag
    13081 cgacgaccga tacctctacc ttgatggtcc agcctcactg ctaaggccaa aatattaaag
    13141 cctttttccg agtaaagcga ctcgtagcat tcagcatgca gatagcctaa gagcagattg
    13201 gtcttagtat cagcatagcc cagcaaataa tgatgcttat cggatcttag tttttccaat
    13261 tggctttttg tcaattcaag agaaaccttg taccccaagg attgatcatt aatgtcacaa
    13321 atagcttgac aatctgtttg atctagtggt cttagcatag ccttacctcc tctaaaatgg
    13381 cagctctgga accttagcta ataattgctc cttagtaata gcaccttgtc gtaaaatact
    13441 gaccttaggt gacgataaat ccaaaatagt agaatccttc cctgtcaaat aggcatcatc
    13501 agcataacca tcaacctttc catcaaatgc cttgacaatg tcattaaagc attttccact
    13561 ctttgagcct gacaggttag cagatggccc aatcaaggga cccgttgctc tgataatttt
    13621 agctgtgaga gggtgactgg gtagtcgaaa gccaactgtt tttagcccag aattaatcca
    13681 atagggtgtc tgggcattgg cttttaggat aatcgtaagt ggaccaggta aaaaagcctc
    13741 gtacagcttg ttaagatagg caggctgctg cttagaaaaa gccaaaatac tctcaaaatc
    13801 agccacatta aggttcatag ccttgtcgcg aggccttttt ttgagacgat aaacagcatt
    13861 aacagcctct tcatttaagg cctgagcaaa aagaccataa actgtctcag ttggtaaaat
    13921 aagagctcca ccagccttaa ttgtctctat caaatgtgtt atcatcaaca accaccattc
    13981 tttctttacc cagcatatcc ttaagcactc tgatacgctt ttgagggaaa cgcttggata
    14041 agagcctttt taagccttct ccctgcttgt agcctatttc aaaatagagc ttaccacttg
    14101 tcgtcagata agcactagct tgttcgataa tgcgtcggta aatagaaaag ccattttctg
    14161 cagcaaataa ggccaaatgc ggctcagatt gataaacatt caagccaacc tcgtccttat
    14221 cctcataggc aatataggga gggttagaaa caatgatgtc aaactgccct gatagcttgc
    14281 taaaaaggtc tgactgctca aaggctatct ctacatgatg atctaaagcg tttgagtaag
    14341 caaggctcaa ggcatcagct gaaatatcag aggctgtgac ctgccagtta ggtcttgctt
    14401 tttttaaagc aattgcaata gcaccactgc ctgttccaat gtctaaaacg gatttgcgag
    14461 tagcgtcatt ttccttcaag ataagctcaa ctaattcttc cgtctctggt cttgggatta
    14521 gcacgcgcga atccactgca agcaccagat ctctaaaata agccctgcct gtgatatatt
    14581 gtggcgatac atgctggcta agcgctaaaa aaatccgctc taataaggct tgatcctctg
    14641 aagtgacctc ttgattttga tgaagcaaaa agtcaaggct tgtccactgc tttaattctt
    14701 taaaaacata ggcgaggttt tcacgatcct cacctatgtt ttctagcctg tcttcgtagg
    14761 ctcttagttg cttagcatag ttcattggtt atttagcgat tctaatttct gagtttgatc
    14821 atatagcact aaagcgtcaa caatctcgtc taactttcca gacaaaatgg tgtctaattt
    14881 ttgcagggtt agaccgatac ggtgatctgt cacacgattt tgtgggaaat tataggtccg
    14941 aatccgttca gaacgatcac ccgtaccgat agttgattta cgctctgcgt cctgctcgtc
    15001 ctgtgcgatc tgtgcaaaat gatctgctac acgtgcccga ataatcttca tagccttgtc
    15061 acgattcttt tgctgcgttc tttcctcttg catctcaacc ttgatgtttg ttgggagatg
    15121 gacgatacga acagcggttg ccaccttgtt gacattttgt ccgccagcac cagaagcatg
    15181 gtaaatatca atacgaaggt cctttggatc aatgtcgtac tcaacttctt ctacctctgg
    15241 catgactaag acagtcgcag ttgaagtatg cacgcgccct tggctttctg ttacaggaac
    15301 acgctgtacg cgatgagcac ctgattcgta ttttagcttg gaataaacag attgtcctga
    15361 aaccatagca acaacctctt taatccctcc aacaccatta taggaagcct ccattacctc
    15421 aaagcgccag ccttggcttt cggcaaattt ttggtacatg gctaagagat caccggcaaa
    15481 tagagcagcc tcatcaccac ctgcggcacc acgaatttcc aagataatat ttttatcatc
    15541 atttggatct ttgggaagca gcaaaagctt taacttgtcc tcataggctt ccttggcaga
    15601 cttggcctct tttagctcct ccttggccat ctcttcaatg tcaggatcgc cgccggcttc
    15661 cttaatcatc tcctcagcgt catcaatgga ttggataata gccttatact gacgataagc
    15721 tgctactgtt tctcgtgtgc tagcctcttc ctttgacaga gccataaaac gtttggtgtc
    15781 agaaacaacc tccggatcac ttaataattc gcctaattct tcataacggt cctcaacggc
    15841 ctgtaattga tcataaatat tcattagggg gtattctctc ctctttttac ttgttttagt
    15901 tgttattaga ttggtgggtg aaaataatgc ttgcgacaaa ctggaatata ggtctcattg
    15961 ccaccaattt gaatctgtgc tccctcataa acgggcttac catgttctgt tcgcaatacc
    16021 atagttgctt ttttgctgca atattgacag atggttttta tctcatcaat cttatcagct
    16081 aacagtaaca ggtatttgga gccttcaaac aattcatttt gaaaatcatt ttttaagcca
    16141 aaggccatca ctggaacatt tagctcatca accacacgtg ctaaatcata gacattttgc
    16201 ttgcttaaaa attgacattc gtcaatcaag acgcaatagg gcttctcctg caattcagca
    16261 ataaatgcaa aaatatccat atcattcgaa attggtacag cctcacgacg catgccaatc
    16321 cgactagaaa caatgccaaa gccatcacgt gtgtctagcg cacttgtcat aatcacaaca
    16381 ggcttcccct gttcttcata attgtgtgct accttcaaga tttcaatggt ctttcctgaa
    16441 ttcattgttc catatttgta atataattga gccaaaatgg agattcctac cttcttcttt
    16501 tgtcctactt attctatcat atttgtccct atttggcgat tgccttatct gaaaatctta
    16561 ttttcacaac agctaaatcc tgtgctgttg agctaaggtt aggctttttg aagctgacat
    16621 gctacaatag aggtatcatt aaaaaaagga gattgactat tatgccattt gtaacgattg
    16681 acctgtttga ggggcgtagc caagaacaaa aaattgccct agcgcgtgag gtgacagagg
    16741 ttgtttctcg tatcgcacag gctccaaaag aagcgattca tgttgtaatc aatgacatgc
    16801 ctgaggggac ctatttcccg catggtgaga tgaaaaccaa agcctaatgc ctaagtccca
    16861 cttatctagg tgggcttttc ctatttgaaa aggagggcct gatgatagct actgatcaga
    16921 tcaagatgat gggaacaatc attgatattt gcattgactc atcaaaagca aagcagcaag
    16981 cagctactat ccgagagcta ctaacccttt acaatcaccg tttttcggcc agtgacgaca
    17041 gctctgaatt aatggcaatc aaccatatgg caggtattca gccagtgcgt gtgcattcag
    17101 atttgtttga cttaatctca atcggaaaag agcatagctt ggcttatcca agcaacctta
    17161 atatcacact tggtccttta gtgcaaagct ggcgcatcgg cttttcagac gctaagcttc
    17221 cagatgaagc aactattgat cgcagactaa gactaaccaa tcctaatcat atcatc
//
LOCUS       DARYYD010000042        16280 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.043, whole genome shotgun sequence.
ACCESSION   DARYYD010000042 DARYYD010000000
VERSION     DARYYD010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16280)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16280)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16280
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.043"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            320..530
                     /locus_tag="TV188_001424"
                     /pseudo
     CDS             320..530
                     /locus_tag="TV188_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(622..4257)
                     /gene="rpoC"
                     /locus_tag="TV188_001425"
     CDS             complement(622..4257)
                     /gene="rpoC"
                     /locus_tag="TV188_001425"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEL1534768.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRAKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEPKSLLTEREYREKIQ
                     EYGHGSFIAKMGAEAIQDLLKRVDLVTEIAELKEELKTATGQKRIKAVRRLDVLDAFH
                     KSGNKPEWMILNILPVIPPDLRPMVQLDGGRFAASDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVIREIVAREFAGNVKAAKRMVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARLLMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEDA
                     GREGEGMVFKDKDEAVMAYRNGYVHLHSRVGIAVDSMPSKLWKDSQRHKIMVTTVGKI
                     LFNDIMPEDLPYLQEPNNANLTEGTPDKYFLKPGQNIQEVIDSLPINVPFKKKNLGNI
                     IAETFKRFRTTETSAFLDRLKDLGYYHSTLAGLTVGIADIPVIDNKAEIIEAAHHRVE
                     EINKAFRRGLMTDDDRYVAVTTTWREAKEALEKRLIETQDPKNPIVMMMDSGARGNIS
                     NFSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADS
                     GYLTRRLVDVAQDVIIREDDCGTDRGLLIRAITDGKEVTETLEERLQGRYTRKSVKHP
                     ETGEVLIGADQLITEDMARKIVDAGVEEVTIRSVFTCATRHGVCRHCYGINLATGDAV
                     EVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRIQEIFEARNPKGEAV
                     ITEVKGTVIEIEEDASTRTKKVYVQGKTGMGEYVVPFTARMKVEVGDEVNRGAALTEG
                     SIQPKHLLEVRDTLSVETYLLAEVQKVYRSQGVEIGDKHVEVMVRQMLRKVRVMDPGD
                     TDLLPGTLMDIADFTDANKEIVISGGIPATSRPVLMGITKASLETNSFLSAASFQETT
                     RVLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMVRYRNIEPQAINEVEVIEEAEATE
                     EPAIIKE"
     gene            complement(4348..7914)
                     /gene="rpoB"
                     /locus_tag="TV188_001426"
     CDS             complement(4348..7914)
                     /gene="rpoB"
                     /locus_tag="TV188_001426"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEL1534769.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFQDFLDSG
                     LKEVFEDVLPISNFTDTMELEFVGYEFKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELETDSKDIAYTRIDRTRKIPFTTLVRALGFSGDDEIIDIFGDSELVR
                     NTIEKDIHKNQSDSRTDEALKEIYERLRPGEPKTADSSRSLLTARFFDARRYDLAAVG
                     RYKINKKLNIKTRLLNQIIAENLIDSETGEILVEAGTEMTRSVIESIEEQLDGDLNKF
                     VYTPNDYAVVTEPVILQKFKVVSPVDPDRVVTIVGNANPDDKVRALTPADILAEMSYF
                     LNLAEGLGKVDDIDHLGNRRIRAVGELLANQFRIGLARMERNVRERMSVQDNDVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSFGHLNKYGFIQTPYRKVDRVIGRVTNEIV
                     WLTADEEDEFTVAQANSKLNPDGTFAEEIVMGRHQGNNQEFPASQVDFVDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLIDPKAPYVGTGMEYQAAHDSGAAVIAQH
                     NGKVVFSDAERVEVRREDGSLDVYHITKFRRSNSGTAYNQRTLVKIGDIVEKGDFIAD
                     GPSMEKGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKEDVYTSVHLEEFESETRDT
                     KLGPEEITREVPNVGEEALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGGDGIVRDVKIFTRANGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARNLGIHIATPVFDGATSEDLWETVREAGMDSDAKTVLYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDVNGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDN
                     EVELRDLDEGEDDDVMHVDDLEKAREKQAQETQDIAESTEDN"
     gene            complement(8176..10476)
                     /locus_tag="TV188_001427"
     CDS             complement(8176..10476)
                     /locus_tag="TV188_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014611927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1534770.1"
                     /translation="MVKWKKNQTSKNHQRLELVDFGTVFLRTLKFMSSFFYVAVFLFG
                     MLGAGMAFGYLASQIDSVKIPSKESLVKQVESLTMMSQITYSDNSLISGIDTDLLRTP
                     VANDAISDNIKKAIVSTEDDNFQRHNGIVPKAIFRATLASVLGFGESSGGSTLTQQLI
                     KQQVLGDDPTFRRKSKEIIYALALERYMSKDDILSHYLNVSPFGRNNKGQNIAGVEEA
                     ARGIFGVSAKDLTVPQAAFLAGLPQSPIVYSPYLPTGQLKSADDMAYGIKRQQNVLYN
                     MYRTGVLTEKEYRDYKAYPISNDFIKPETVTANTHDYLYYSVLAEAQKAMYSYLIKRD
                     KVPAKDLKNDETKAAYEERALTELQHGGYTVKTTINKPIHQVMQKAAAQFGGLLDDGT
                     GTVQMGNVLTDNATGAVLGFIGGRDYAQNQNNHAFNTVRSPGSSIKPIIAYGPAIDQG
                     LMGSASVLSNYPTTYSSGQKIMHVDSEGTAMMPLQEALNTSWNIPAFWTQKLLRDKGV
                     DVENYMSKMGYRIADYSIESLPLGGGIETSVAQQTNAYQMIANNGLYQKQYMVASITA
                     SDGSVVYQHEAKPVRIFSAPTATILQELLRGPISSGATTTFKSRLAGINPSLAGADWI
                     GKTGTTENYTDVWLVLATPRVTLGGWAGHDDNTSLAPLTGYNNNSNYMAYLVNAISQA
                     DPNLFGLGQRFSLDPGVIKASVLKATGLKPGTVTINGQTISIGGELTTSLWAQKGPGA
                     TTYRFAIGGTDADYQKAWGGFSGRRN"
     gene            10581..11837
                     /locus_tag="TV188_001428"
     CDS             10581..11837
                     /locus_tag="TV188_001428"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEL1534771.1"
                     /translation="MNIFEELKARGLVFQTTDEEALVKALTEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERILQTKETVLDWSQKIK
                     EQLSCFLDFDNGENKAELVNNYDWFSQISFIDFLRDVGKHFTINYMMSKDSVKKRIET
                     GISYTEFAYQVMQGYDFYELNAKHNVTLQIGGSDQWGNMTAGTELLRKKADKTGHVMT
                     VPLITDATGKKFGKSEGNAIWLDAKKTSPYEMYQFWLNVMDDDAVRFLKIFTFLSLDE
                     IAAIEEQFNAARHERLAQKTLAREVVTLVHGEAAYQQALNITEQLFAGAIKNLSAAEL
                     KQGLSNVPNYQVQAEDSLNIVDMLVTAGISPSKRQAHEDLQNGAIYLNGERLQDLDYS
                     LSTADRIDNQLTVIRRGKKKYAVLTY"
     gene            complement(11872..12681)
                     /locus_tag="TV188_001429"
     CDS             complement(11872..12681)
                     /locus_tag="TV188_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEL1534772.1"
                     /translation="MLEILSYDFMQRAVMAVVAISIFAPILGIFLILRRQSLLSDTLS
                     HVSLAGVAFGVVLGVSPTFTTIIVVVLAAILLEYLRVVYKHYMEISTAILMSLGLAIS
                     LIIMSKSTSSSSMSLEQYLFGSIITISTEQVAALFVIALIILALTILFIRPMYILTFD
                     EDTAYVDGLPVRVMSVLFNIVTGVAIALTIPAAGALLVSTIMVLPASIAMRLGKNFKS
                     VIFLGIMIGFTGMLSGIFLSYFWETPASATITMIFIAIFLVVNLLSFIRQK"
     gene            complement(12674..13393)
                     /locus_tag="TV188_001430"
     CDS             complement(12674..13393)
                     /locus_tag="TV188_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEL1534773.1"
                     /translation="MRYISVENLSFQYDSEPVLEGISYHLDSGEFVTLTGENGAAKST
                     LIKATLGILKPRAGQVTIAKQNIHGKKLRIAYLPQQVASFNAGFPSTVYEFVKSGRYP
                     RSGWFTRLSKHDEEHVRTSLESVGMWDSRHKRIGSLSGGQKQRVVIARMFASDPDIFV
                     LDEPTTGMDSGTTDTFYELMHHSAHRHGKAVLMITHDPEEVKAYADRNIHLIRNQRLP
                     WRCFNIHDAEADESKGGSFHA"
     gene            complement(13396..13839)
                     /locus_tag="TV188_001431"
     CDS             complement(13396..13839)
                     /locus_tag="TV188_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent MarR family transcriptional
                     regulator"
                     /protein_id="HEL1534774.1"
                     /translation="MTILEKKLDNLVNRILLKAENQHELLFGACQSDVKLTNTQEHIL
                     MLLSQEKLTNTDLAKRLNISQAAVTKAIKGLIKQEMLAGTKDTVDARVTYFELTDLAR
                     PIAKEHTHHHDKTLAVYHRLLAHFSAEEQVIVEKFITAFAEELEG"
     gene            complement(13909..14760)
                     /locus_tag="TV188_001432"
     CDS             complement(13909..14760)
                     /locus_tag="TV188_001432"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HEL1534775.1"
                     /translation="MTAIIERAPAKINLGLDIQGKRPDGYHDLSMVLVSVDLCDYITV
                     DHLEEDRILLTSNCPRLPINEHNDVYKAAYLLKERFQISTGVSIFLDKRVPVCAGMGG
                     GSSDAAAAIRALNQLWQLKLSPRQMIDIGMQIGSDVPYCLFAGCAQVTGKGEVVKPIN
                     GRLSSWVVLVKPEFGISTRTIFWDIDCETISRVPIEDLVSAIEAGDYQRLLATMGNSL
                     EDISIAKRPFIQKVKDKMLQSGADIALMTGSGPTVFALCQTEKQANRVVNSLKGFCKE
                     VYKVRTL"
     gene            complement(14975..15499)
                     /locus_tag="TV188_001433"
     CDS             complement(14975..15499)
                     /locus_tag="TV188_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HEL1534776.1"
                     /translation="MVEYWDIYTMNRLKTGRLMERGAAFVEGAYHLVVHACVFNDKGE
                     MLIQQRQKDKEGWPSYWDITVGGSALAGETSQEAVMRELKEELGLTLDLAGVRPHFSI
                     TFDNGFDDTFLILQAVDVRKLVLQTEEVQAVRWASRDEILAMIDAGIFIPYFKSKIDM
                     CFELVGQYGAIKWS"
     gene            complement(15993..>16280)
                     /locus_tag="TV188_001434"
     CDS             complement(15993..>16280)
                     /locus_tag="TV188_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1534777.1"
                     /translation="QSQRGEKGEQGKDTKPSAPKAPEQSPAPQVPKTSEQQSASPKVP
                     APKSAPSKSAAPAAQKGILPATGETNHPFFTLAALGVIASAGLLTLKRKNN"
BASE COUNT         4775 a         3981 c         3119 g         4405 t
ORIGIN      
        1 taaaattgca agcgcagcga tactagaata aataagtttt tttagtctca taatctactc
       61 ctttttaatc tctaaaatta aaacaaacaa tctttaccgg taatagttaa ttttactact
      121 aaaaataaac tcctttctgg taaaatgaac cacctaagaa acctacatgt acagaataac
      181 atatattttc cttaaaaata agactatatt ttaaaaaaac aaatgataaa attaaatttt
      241 ggaagctttt tttataataa aataatttat cgatttttcc actattaagt tatttttgat
      301 taacattttt aaaatagttt tgtctatcta catacaatat aaagactata tcactaatgc
      361 cattgaacta ccttattcta acgccaagtt tgaagcgact agcaaactga tcaaagacat
      421 caagcgcaat gcatttggat tcagaaacgt tgacaatttc aagaaactta tctatgcttg
      481 ctttgaacat gacaaaagag aagacgacct tcgtctcctc tcgtgcttag ttatcagtca
      541 cctactatag ttgacatgga gcccaattaa tctaatgatt ttagcatgat aaaaggagct
      601 aaggctagct ccttttattt cttattcctt aataattgct ggctcttctg tagcttcagc
      661 ttcttcgata acctcaacct cattgatagc ttgcggttca atgttacggt aacgaaccat
      721 accagtacct gctggaatga tcttaccaat gataacattt tccttaagcc ccaatagatg
      781 gtcttttttg cctcggatag cagcgtctgt cagcacgcga gtggtttcct ggaaggaagc
      841 tgctgatagg aatgagttag tctcaagtga ggcttttgtg attcccataa gcactggacg
      901 agaggtcgca ggaatacctc cagagataac aatctcctta ttggcatctg taaagtctgc
      961 aatatccatt aaggttcctg gcagaagatc tgtatcacct ggatccatga cacgtacctt
     1021 gcgaagcatt tgacgaacca taacctcaac gtgcttgtct ccgatttcta ccccttggct
     1081 gcggtaaacc ttttgaacct cagcaagcaa gtaggtctca actgacaagg tatcacgaac
     1141 ctcaaggagg tgcttaggct ggattgaccc ttctgtaagg gcagctccac gattgacctc
     1201 atcaccaacc tcaaccttca tacgcgctgt aaatggcaca acatattcac ccatgcctgt
     1261 tttaccttga acgtagacct tcttagtacg agttgatgcg tcctcttcaa tctcaataac
     1321 agtcccctta acctctgtga taactgcttc ccctttaggg ttgcgcgctt caaagatttc
     1381 ttggatacga ggaagaccct gtgtgatatc ggtattagag gcaacccctc ctgtgtggaa
     1441 ggtacgcatg gtcagctgag taccaggctc accaatagat tgggcagcga tagtaccaac
     1501 agcctcacca acctcaaccg catcacctgt cgctaggttg ataccgtaac agtgacgaca
     1561 cactccatga cgagtagcac aggtaaatac tgagcgaatg gtaacctctt caacaccagc
     1621 atcaacaatc ttgcgagcca tgtcctcagt gattaattgg tcagcaccaa tcaatacctc
     1681 accagtttca gggtgcttga ctgatttacg agtgtatcga ccctgcaagc gctcctcaag
     1741 tgtttcagtg acttccttgc catctgtgat agctcgaata agaaggcctc ggtctgtacc
     1801 acaatcgtcc tcacgaatga tgacatcttg cgcaacatca actaaacgac gtgtcagata
     1861 gcctgagtca gctgtcttaa gagccgtatc agtcataccc ttacgagcac catgagttga
     1921 gaagaacatt tccaaaacag acaagccttc gcggaagtta gacaggatag gaagctccat
     1981 aatacggcca ttaggagcag ccatcaagcc acgcataccg gcaagctgcg agaagttaga
     2041 gatgttacca cgcgctcctg agtccatcat cataacgatt gggttcttag gatcctgtgt
     2101 ttcaatcaga cgcttctcaa gggcttcttt tgcctcgcgc catgttgttg tgactgcaac
     2161 atagcgatca tcatcagtca tcaagcctcg acggaaggcc ttattaattt cctcaacacg
     2221 atggtgagca gcctcgatga tctcagcctt gttgtcaata accggaatat cagcgatccc
     2281 aaccgtcaag cccgcaaggg ttgaatgata gtagccaagg tccttcaagc ggtcaagaaa
     2341 ggccgatgtt tctgttgtac ggaaacgctt gaaggtttcc gcaatgatgt taccaagatt
     2401 tttcttcttg aagggcacat tgatcggtaa gctatcaata acctcctgaa tattctgacc
     2461 tggcttcaag aaatatttat ctggagtgcc ctctgtcaag ttagcattat ttggctcttg
     2521 gaggtaagga aggtcctctg gcatgatgtc attaaacaag atcttaccga ccgttgtcac
     2581 catgattttg tgtctttgac tatccttcca aagcttgctt ggcatactgt caacagcaat
     2641 accaacacga ctatgaaggt gaacatagcc attacggtaa gccattaccg cttcgtcctt
     2701 gtccttaaag accatacctt cgccttcacg accagcatct tccattgtta ggtagtagtt
     2761 tcctagcacc atatcctgag aaggtgttac aactggctta ccgtccttag ggttaagaat
     2821 atgctcagca gcaagcatca acaaacgagc ctctgcctgt gcttcctctg aaagcggcac
     2881 gtgaatagcc atttggtctc cgtcaaagtc ggcattgtag gcctcacaca caagcgggtg
     2941 aagacgaaga gccttaccat caataagcac cggctcaaag gcctgaatcc ctaatctgtg
     3001 aagggtaggt gcgcggttaa gcaggactgg atgctccttg ataacctctt ctagaatatc
     3061 ccagatacgc tcatcgccac gctcaaccat acgcttagct gctttgacgt tgccggcaaa
     3121 ttcgcgggca acaatctcac gtatcacaaa tggcttgaaa agctcaatag ccatctcacg
     3181 tggtacacca cattggtaca tttttagcgt tggacccaca gcaataactg aacgacctga
     3241 gaagtcaaca cgcttcccaa gcaggttttg acgaaaacgc ccttgttttc ctttaagcat
     3301 gtggctcaag gatttaagcg gacgactacc aggtcctgta ataggacgac cacgacgacc
     3361 attatcaatc aaagcatcaa ccgcctcttg cagcatacgc ttttcatttt gcacaatgat
     3421 accaggcgca ttaagctcca acaaacgtgc taaacgatta ttacggttaa tgacacgacg
     3481 gtaaaggtca ttcaagtctg aggctgcaaa gcggccaccg tccaattgca ccataggacg
     3541 aagatctggt ggaatgaccg gcaagatgtt caggatcatc cattctggct tattgcctga
     3601 tttatgaaag gcatcaagca catctaaccg acgaacagcc ttgatacgct tttggcctgt
     3661 tgctgttttt aattcttcct ttagctcagc aatttctgtg accaaatcaa cacgctttag
     3721 gaggtcttga atagcctctg cccccatttt agcaatgaat gagccatgtc catattcttg
     3781 gattttttca cgatattcac gctctgtcaa tagtgatttt ggctcaagcg gtgtgtcctt
     3841 tggatcaata accacataag ccgcaaaata gattacctcc tcaagagcac gaggactcat
     3901 atcaagagtc aagcccatac gagatgggat tcccttaaaa taccagatat gtgagacagg
     3961 tgccttcagc tcaatgtgtc ccatgcgttc acgacgaacc tttgcacgcg ttacctcgac
     4021 cccacaacgg tcacagacaa tgcccttata gcgaatacgt ttatatttgc cacacgcaca
     4081 ctcccaatcc ttggttggtc caaaaatgac ttcgtcaaaa agaccctcac gttctggttt
     4141 taatgtacgg tagttgattg tttcaggttt tttaacttca ccataggacc atgaacggac
     4201 cttacttggt gaagctaatg tgatttgcat acttttaaaa cgatttacgt caaccactag
     4261 ttttaccttt ctgcctttga tgacttacta gcagctaggg caaatagccc tagtctagtc
     4321 attatttctg ttacaaatgt ttatgattta gttgtcttca gttgattcag caatatcttg
     4381 agtttcctga gcctgctttt cacgcgcttt ttcaagatcg tcaacgtgca tcacgtcatc
     4441 gtcttcgcct tcatcaagat cacgaagctc aacttcatta tcgtcttcat caaggacacg
     4501 catatcaaga ccaagtgatt gcaattcttt cacaagaacg cggaaagatt ctggtacacc
     4561 aggctttgga attggcttac ctttggtaat cgcctcataa gctttcaagc gaccattcac
     4621 atcgtctgac ttataggtca agatttcctg aagaacgttt gaagcaccat aagcctcaag
     4681 agcccatacc tccatctcac caaaacgttg gccaccaaac tgagctttac ctccaagcgg
     4741 ctgttgggta accagtgagt atggtcctac agaacgcgcg tgaagcttat catcaaccat
     4801 gtggtgaagc ttaatcatat acatgacacc aactgacaca cgattatcaa acggctcacc
     4861 agtacggcca tcataaagaa cagtcttagc atcgctatcc atacctgctt cacgaacagt
     4921 ttcccaaagg tcctcagacg tagctccgtc aaagaccggt gttgcgatat ggatacccaa
     4981 attacgagca gccataccta ggtgaagctc cataacctgt ccaatgttca tacgagacgg
     5041 caccccaaga gggttcagca tgatgtcaac aggggttccg tctggcagat atggcatatc
     5101 ctcaaccggt acaatacgtg agacgacacc cttgttacca tgacgcccgg ccattttatc
     5161 tccgaccttg attttacgct tttgagcaat gtaaacacgc accagcatat taacacctga
     5221 ttgaagctca tcaccatttg cgcgtgtaaa gatcttcaca tcacgtacaa tcccgtcacc
     5281 accatgagga acacgtaacg aggtatcacg aacctcacgt gatttatcac caaagatagc
     5341 atgcaggaga cgttcttcag cagaaaggtc tttttcaccc ttaggagtta ccttaccaac
     5401 aagaatatcg ccttccttga cctctgcacc gatacggata atacccattt catcaaggtc
     5461 cttgagggct tcttcaccaa cgtttggcac ttcacgtgtg atttcctcag gtccaagctt
     5521 tgtgtcgcgt gtttctgatt caaactcctc caagtgaaca gaggtataaa cgtcctcctt
     5581 cacaagacgc tcactcatga taaccgcgtc ctcaaagttg tacccttccc aggtcatgta
     5641 agcaacgatt ggattttgac caagagccat ctcacctttt tccatagaag ggccatcagc
     5701 gataaagtca cccttttcaa caatatcacc tattttaaca agggttcgtt ggttgtaggc
     5761 agtaccagag tttgaacggc ggaattttgt gatgtggtaa acatcaagtg aaccgtcctc
     5821 acgacgcacc tctactcttt cagcatctga aaagacaacc ttaccattat gctgggcaat
     5881 taccgcagca cctgaatcat gagctgcttg atattccata cccgtaccaa cataaggagc
     5941 ctttggatca atcaatggca cagcctgacg ctgcatgtta gctcccatta gggcgcggtt
     6001 ggagtcatcg ttttcaagga aaggaataca tgctgtcgca acagcgacta cctgcttagg
     6061 agacacgtca acaaagtcaa cctgactagc aggaaactct tggttattac cttggtgacg
     6121 tcccatgaca atctcttcag caaaggtacc gtctggattg agcttagaat tagcctgagc
     6181 cactgtaaac tcatcctctt catcagcagt tagccaaaca atctcattag tcactcggcc
     6241 aatcacacga tcaaccttac ggtaaggggt ttgaataaag ccgtatttgt tcagatgtcc
     6301 aaatgaagac aggttattaa tcaaaccgat atttggccct tcaggtgttt caatcggaca
     6361 catacgacca tagtgagtgt agtgcacgtc acgcacctca tagccagcac gatcacgtgt
     6421 caaaccacca ggtcctaagg cagacaaacg acgtttgtgc gacaactcag acaatgggtt
     6481 gtgctgatcc atgaactgtg atagctgtga agaaccaaag aattctttga cagccgccgt
     6541 tacaggacga atgttaataa tctgttgtgg agtcaacaca tcgttatcct gtacagacat
     6601 acgctcgcgg acattgcgct ccatacgagc aagaccaata cggaattggt tagcaagcaa
     6661 ttcaccaact gcacggatac gacgattacc taagtggtca atgtcatcga cctttccaag
     6721 accttcagca aggttaagga aataagacat ctcagccaaa atatcagccg gagtaagggc
     6781 acgaacctta tcatctgggt tagcattacc aacgatcgtc accacacgat caggatcaac
     6841 tggtgaaacc accttgaatt tttgtaggat cacaggctct gtcaccaccg cataatcgtt
     6901 tggtgtgtag acaaacttgt tcaaatcccc atcaagctgc tcttcgattg actcaatcac
     6961 actacgagtc atctctgttc cagcctcaac cagaatctct ccagtctcac tatctattag
     7021 attttcagca ataatttgat tcaaaagacg tgtcttgatg ttcagctttt tattaatctt
     7081 ataacggcca actgctgcca agtcataacg gcgagcatca aagaaacgag ctgtcaaaag
     7141 gctgcgtgag ctatcagctg tctttggctc acctggtctt aagcgttcat aaatttcctt
     7201 aagagcctca tctgtacgtg aatcgctttg gtttttatga atatcctttt caatggtatt
     7261 gcgaacaagc tcactatcac caaaaatatc aataatttcg tcatcaccag aaaaaccaag
     7321 tgcacgcact agcgttgtaa atgggatttt acgcgtacgg tcaatacgag tataagcaat
     7381 atcctttgag tcagtttcta gctctagcca agcaccacga ttagggataa ctgttgagcc
     7441 ataaccaacc ttaccatttt tatcaacctt gtcattgaaa taaacaccag gagaccgaac
     7501 cagctgagaa acaataatac gctctccacc gttgatgata aaggttccca tttcagtcat
     7561 aatcggaaaa tcaccaaaaa agacctcttg tgttttgatt tcgccagttt ccttattaat
     7621 caggcggaag gtcacaaaga ttggtgcaga atagcttgca tcatggatac gagcctcttc
     7681 aagggtatat ttaggctcct taaattcgta accaacaaac tcaagctcca tcgtgtctgt
     7741 aaagtttgag attggaagca catcttcaaa tacttccttc aagcctgaat ctaagaaatc
     7801 ttggaatgaa tcagtttgaa tttcaatcaa atttggtaaa tcaagaacct ctttgattct
     7861 tgaaaaacta cgacgggtac gatgtttccc gtattgaacg tcatgtcctg ccaagttttt
     7921 agctcctttt tctttttaag ctttgctatc aagcaaacaa ttgcaacatc aatatttgtc
     7981 ttaagtggta tttttagaat ctttaaattt ttgttacaaa attgattttt atctaaaaat
     8041 aggcacaaaa agagcagcta aatcggacct tatcagtgtg atttaactgc tgttctttct
     8101 agctggacaa tatttcagct agattagacg acaaatagtt atagatatta tacactattt
     8161 gtctggaaaa tacaactaat ttcttctacc actaaaacct ccccaggctt tttgatagtc
     8221 tgcgtctgtt ccaccaatgg caaacctata ggtagttgct ccgggtccct tttgagccca
     8281 aaggctggtt gttagctctc caccgatgga gatggtttgg ccattgatcg tcactgtacc
     8341 cggctttaga ccagtggcct tcaagacaga agccttgata acaccaggat ccagtgaaaa
     8401 ccgctgacca aggccaaaaa gattgggatc agcctgactg atggcattaa ccaaataagc
     8461 catataattt gaattattat tgtatcccgt cagtggtgca agcgaggtat tgtcatcatg
     8521 gcctgcccaa ccacccaaag taacccttgg agtagctaag accagccaga catcggtata
     8581 attttcggtt gttcctgttt tacctatcca gtcagcacct gcaaggcttg ggttgatccc
     8641 tgctaatcgg cttttaaaag tggttgttgc cccagatgaa atcggccctc tcaagagctc
     8701 ctgtaaaatc gttgctgtcg gagctgagaa aatacgaacc ggcttggcct catgctgata
     8761 aacaacggat ccatcactag ctgtgatact agccaccata tattgctttt gataaagacc
     8821 attattagca atcatctgat aagcattggt ctgctgggct accgaggtct caatcccacc
     8881 accaagtggc agactttcaa tggaataatc agcaatccga tatcccattt tactcatata
     8941 gttttcaaca tcaacgccct tatcacgcag cagcttttga gtccaaaagg ctggaatatt
     9001 ccatgaggta ttaagcgcct cctgcagggg catcattgct gttccttcac tatcgacgtg
     9061 catgattttt tgaccgctgg aataggtcgt cggatagttg gataggacac tagcacttcc
     9121 cattaatccc tgatcaatgg caggtccata agcaataatc ggcttaatgc tagagcctgg
     9181 agagcgaaca gtattaaagg catgattgtt ttgattttga gcatagtctc tcccaccaat
     9241 aaagcccaaa acagcacctg tagcattgtc cgttaggaca ttgcccatct gcactgtccc
     9301 agtgccatca tctaacaagc caccaaactg agctgccgct ttttgcatca cctgatggat
     9361 tggcttattg attgttgttt tgacagtgta gccgccatgc tgcagctcag ttaaggctcg
     9421 ctcctcatag gcagccttag tctcatcatt ttttaaatct ttagcaggca ccttatctcg
     9481 cttaatcaga tagctataca tggccttttg tgcctctgcc aagacagaat agtagaggta
     9541 atcatgagta ttggcagtga ctgtttcagg tttgataaaa tcattgctaa taggatatgc
     9601 cttataatca cgatattctt tttctgtcag cacacctgtt cgatacatat tgtagaggac
     9661 attttgctgg cgcttaatcc cataggccat atcatcggct gattttaact gccctgtcgg
     9721 caaatacggc gaataaacaa tcgggctttg cggaagccct gccaaaaagg ccgcctgcgg
     9781 aaccgtcaaa tccttggcag agactccaaa aatgccacgc gcagcctcct ccacacctgc
     9841 aatgttttgt cccttattat tacgaccaaa aggcgacacg tttaaataat gtgataaaat
     9901 atcgtccttt gacatgtaac gctctaaggc cagtgcatag ataatttcct ttgattttcg
     9961 cctaaaggtc ggatcatcgc ccaagacttg ctgcttaatc aactgctgtg tcagcgtaga
    10021 gccaccactt gactccccaa agcccaaaac agaggccaga gtcgcacgaa aaatcgcctt
    10081 tggcacaatg ccattatggc gctgaaagtt gtcgtcctca gttgagacaa tagccttttt
    10141 gatattgtct gaaatcgcat cattagcaac cggtgtccta agcagatccg tatcaatgcc
    10201 tgaaatcaag ctattatctg aataggtaat ctgtgacatc atggtcaatg attcaacctg
    10261 cttgacaaga ctttccttac ttggaatttt taccgagtca atttgactgg ctaaatagcc
    10321 aaaggccata ccagcaccca gcatgccaaa taaaaagaca gctacataaa aaaagctcga
    10381 catgaatttt aatgtgcgca aaaagaccgt tccaaaatca actaattcta atcgctgatg
    10441 atttttgctt gtttgattct ttttccattt caccataacg tacctcaatc ttcattatac
    10501 caaactttga ttaagcttgc acagccacag tcatttttga tataatgatt cggaaatcat
    10561 aaagaaaatg gagaaagcct atgaatattt ttgaagaact caaagctcgt ggcttggtct
    10621 ttcagacgac cgatgaagaa gcccttgtca aagcattaac agaagggcaa gtatcctatt
    10681 acactggcta tgatccaaca gctgatagcc tgcatcttgg tcatctcgtt gccattttga
    10741 catcacgtcg cttgcagcta gcaggacaca agccctacgc tcttgtcggt ggggcaactg
    10801 ggctgattgg tgatccgtcc tttaaagacg ctgagcgtat cctacaaacc aaggaaaccg
    10861 ttcttgattg gagccaaaag attaaagaac aactctcttg ctttcttgac tttgacaacg
    10921 gtgaaaacaa ggctgagctt gtcaacaact atgactggtt ctcacagatt agctttattg
    10981 acttccttcg tgatgtcggc aagcacttca ctatcaatta catgatgagc aaggattcag
    11041 tgaaaaaacg tatcgaaacc ggaatttcct acaccgaatt tgcatatcag gtcatgcaag
    11101 gctacgattt ttacgagcta aatgctaagc acaatgtgac actgcaaatc ggcggctctg
    11161 accagtgggg taatatgaca gcaggtaccg aattgctccg caaaaaagct gacaagactg
    11221 gacatgtgat gacagtgcca ttgattacag atgcaacagg taaaaaattc ggcaagtcag
    11281 agggtaatgc gatttggctt gacgctaaaa aaacatctcc ttacgagatg taccagttct
    11341 ggttaaatgt tatggacgat gatgcggtac gcttcctgaa gatcttcacc ttcttatcac
    11401 ttgatgagat tgctgctatt gaggagcagt tcaacgcagc acgccatgag cgccttgctc
    11461 aaaagacact tgcgcgtgag gtggtgacac tggttcatgg agaggcagcc taccagcaag
    11521 ccctcaatat taccgaacag ctttttgcag gagctatcaa aaacctttca gcagctgagc
    11581 ttaagcaagg cttaagcaat gtccctaact atcaggttca agcagaagac agcctaaata
    11641 tcgtggatat gttagtcaca gcaggcattt caccatcaaa acgtcaggcg catgaggatt
    11701 tacaaaatgg cgcgatctac ctcaatggag aacgacttca ggatctggat tacagcttat
    11761 ctacagcaga tcgcattgac aatcagttga ccgtcattcg ccgcggcaag aaaaaatacg
    11821 ctgtactaac ctactaatca cagacagcta ggaaaatctt gctttggatg attatttttg
    11881 acgtataaag gacagcaggt taaccacaag gaagatcgca ataaaaatca tcgtaatggt
    11941 cgcacttgcc ggcgtttccc aaaaatagga caagaaaata ccagacagca tgcctgtaaa
    12001 gccaatcata atcccaagaa aaataactga tttaaagttt ttcccaagcc gcatagcaat
    12061 acttgctggc aaaaccataa tcgttgatac caaaagggcc cctgccgctg ggatcgttag
    12121 agcaatagca acacctgtca caatattaaa caagacagac atgacacgca ccggcaagcc
    12181 atcgacgtag gctgtgtcct catcgaaggt caagatatac attggacgaa taaataatat
    12241 cgtcaaggct aaaataatca aagcaatgac aaataaggca gcaacctgct ccgtactaat
    12301 agtaatgata gagccaaaaa ggtattgctc caagctcata ctagaagagc tagttgactt
    12361 actcatgata atcaaggaaa tagccagccc caaggacatt aggatagctg tcgaaatctc
    12421 catatagtgc ttataaacca ccctaagata ttctagcaag atggcagcta gcaccaccac
    12481 aataatcgtt gtgaaggttg gcgaaacacc aagaacaaca ccaaaggcca caccagccag
    12541 agaaacgtgg ctaagcgtat cactcaacaa gctttgacga cgcaaaatca aaaagatacc
    12601 caaaatcgga gcaaagatac tgatcgccac aacagccata acagcacgct gcataaaatc
    12661 ataagataaa atctcaagca tggaatgacc ctcctttgct ctcatcagcc tcagcatcat
    12721 gaatgttgaa gcaacgccaa ggaagccgtt gatttctaat caaatgaata ttgcgatcag
    12781 cataagcctt gacctcctct gggtcatgtg taatcatcaa aacagcctta ccatgtctat
    12841 gagcgctgtg gtgcatcaac tcataaaaag tatctgttgt tccactatcc attcctgtgg
    12901 tcggctcatc aagcacaaaa atatcggggt cagaagcaaa catacgcgca ataaccacac
    12961 gctgcttttg accacctgat agactcccta ttctcttatg ccgactatcc cacatgccaa
    13021 cagactccaa gcttgtccga acatgctcct catcgtgctt acttagtctg gtaaaccaac
    13081 cacttctagg atatctgcct gatttaacaa attcataaac agtcgacgga aagcctgcat
    13141 taaagctggc aacctgctgt ggcaagtaag caattctcag ctttttccca tgaatgttct
    13201 gtttagctat agtcacctgc ccagcccttg gctttaaaat ccccaaggtc gccttgatca
    13261 gggttgactt ggcagcacca ttttcaccag tcaatgtgac aaattctcca ctatccaaat
    13321 gatagctgat tccctctaaa acaggctcac tgtcatactg gaacgagaga ttttccaccg
    13381 atatgtatct cattattacc cttctaactc ctccgcaaaa gcagtgataa atttttcaac
    13441 aatcacctgc tcctccgcag aaaaatgtgc caacaaacga tgataaacag ctagtgtttt
    13501 atcgtgatga tgtgtatgct ccttagcgat tggccttgct agatcagtca gttcaaaata
    13561 ggttactcga gcatcaacgg tatcctttgt tcctgctagc atttcttgct tgatcaagcc
    13621 tttaatcgct ttagttactg ctgcttgact gatatttagc ctttttgcca aatctgtatt
    13681 ggttagcttt tcctgtgaca aaagcatcaa aatatgctcc tgagtatttg ttaatttgac
    13741 atcactctga caagccccaa agagcagctc atgctgattt tcagccttta acaaaatacg
    13801 attaaccaaa ttatcaagct ttttttctaa aattgtcatg atttccctct cctcattaac
    13861 cagttaatta taacatgacg ccccaaaaga cgcaacttca aggctgatct acagcgttct
    13921 aaccttgtag acttccttac aaaagccttt caggctattc accacacgat tggcctgctt
    13981 ttctgtttga catagggcaa ataccgttgg accacttcct gtcatcaggg caatgtctgc
    14041 tcctgactgc agcattttat ccttaacctt ttgaataaac ggccgtttag caatggaaat
    14101 atcctctaag gaatttccca tcgttgcaag caagcgctga taatcacctg cctcaatggc
    14161 tgaaaccaga tcctcaatcg gcactcgaga tatcgtctca caatcaatat cccaaaaaat
    14221 cgttctagta gaaatgccaa attctggctt cactagaacc acccaagagg acaagcggcc
    14281 attgattggc ttaaccacct cgcctttgcc agtcacttgg gcgcagcctg caaaaagaca
    14341 ataaggcaca tcgctaccaa tctgcatgcc aatgtcaatc atctgacggg gactaagctt
    14401 tagctgccac agctgattca atgctctgat tgctgcagcc gcatcacttg agccacctcc
    14461 cataccagca caaacaggta ccctcttatc caagaaaata gagacacctg ttgagatttg
    14521 aaatcgctct ttcagcaaat aagccgcctt gtaaacgtca ttgtgctcat taataggcaa
    14581 tctagggcaa ttagaggtca ataaaatcct atcctcctct aaatgatcca ctgtaatata
    14641 atcacaaaga tctacactaa ctagaaccat agataggtca tgatagccat ctggtcgctt
    14701 gccttgaata tctaagccta gatttatttt tgcaggagct ctctcaatga ttgcagtcat
    14761 aatactcctt tatttgatgt cattatagta tcaaatatac acaatcttca tgaaaaattc
    14821 aaataaatac agttagtatc taatgatgca tagacagcgt gtttgtatca aaacagccaa
    14881 ccatttgtcc ctactagcgt gaggcttcac cagatcagca gccaaaaaac gacaactact
    14941 agcatagcaa gcaaagctaa gacagcagca gtctctatga ccacttgatc gctccatatt
    15001 gccccactaa ctcaaagcac atatcaatct tgctcttaaa gtagggaata aaaataccag
    15061 catcaatcat ggctaaaatc tcatcacgac tagcccatcg aacagcctgt acctcctctg
    15121 tctgaagaac tagcttcctt acatcaacag cctgcaaaat caaaaaagta tcgtcaaagc
    15181 cattatcaaa ggtaattgaa aaatgaggcc ttacaccagc taaatcaaga gtaagtccta
    15241 gctcctcctt cagttctctc atcactgcct cttgtgacgt ctcacctgca agagcgctgc
    15301 cgcctaccgt tatatcccaa tagctgggcc aaccctcttt atccttttgc cgctgctgaa
    15361 tcagcatttc tcccttgtca ttaaagacac aggcgtgaac cactaaatga taagcaccct
    15421 ctacaaaagc agctccacgc tccatgagtc taccagtctt aagacgattc atcgtataaa
    15481 tgtcccaata ctcaaccata caaacacacc tcctgataca gctattacca gatccagtat
    15541 attaatcata tcacaataag catatccaaa acaaccaggt ccagacaaaa caacaattac
    15601 caacctagct taattctttt ttctacaatt ccctacctta aaatgcctcg catagaaaat
    15661 ggacaaaaag atctgttttc ccgagacgta tcaaaaagct caccacgcta acaaactggt
    15721 agttaagatc cccaagcgtc ttactcagtt aacgatatgg tgatacacac agctgacttg
    15781 cctcatcata ttagttacaa aaaaccttaa aggctcaacc caaaagcaca ccaactacat
    15841 caccccatga aagaggaaga caaaacatct actgctgcaa gcaaaaagag accccattag
    15901 ggcctctcta gtgctcatat cagcttttaa actaatcaat cgccttcaag ctaaaggcta
    15961 tcatttagta ggagaaagtt gcaaaagcta atttagttgt tttttctttt tagagttagc
    16021 aggcctgcgc tggcaatgac gccgagagct gcaagggtga agaatgggtg atttgtctct
    16081 cctgtagctg gtaatatacc cttttgagct gctggagccg ctgatttgct tggtgctgac
    16141 ttaggcgctg gtaccttagg actagctgac tgctgctctg aagtctttgg tacctgtgga
    16201 gcaggagatt gctccggggc ctttggagct gatggtttgg tatcctttcc ttgctcgccc
    16261 ttttcaccgc gttggctttg
//
LOCUS       DARYYD010000043        15892 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.044, whole genome shotgun sequence.
ACCESSION   DARYYD010000043 DARYYD010000000
VERSION     DARYYD010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15892
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.044"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(92..562)
                     /locus_tag="TV188_001435"
     CDS             complement(92..562)
                     /locus_tag="TV188_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEL1534778.1"
                     /translation="MLEVIKNWVNICVKEGDKILLLNRQHDDFPGWIQPGGKVNTSES
                     FFEAAVRELKEETGLTALNLQLKGISGFTNPDKPERYVYYDFLCEDFEGKLLTKSREG
                     LPQWHAIADLDKLDMQEDIRQRLPLYWRQGSFERLHYWSDKEKKVVKTITHLYD"
     gene            783..1633
                     /locus_tag="TV188_001436"
                     /pseudo
     CDS             783..1633
                     /locus_tag="TV188_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622164.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            1969..2259
                     /locus_tag="TV188_001437"
     CDS             1969..2259
                     /locus_tag="TV188_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009853345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HEL1534779.1"
                     /translation="MATLERHHKMLLLSMALGAASWLALGLISLPNLAGALGISTANA
                     NTTVNLLSAYSTVSSVVAIVGAVTGVGSIGAGIAATVLYLIKQKGKAAAALW"
     gene            2273..3412
                     /locus_tag="TV188_001438"
     CDS             2273..3412
                     /locus_tag="TV188_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534780.1"
                     /translation="MKHVFKYHKGDILGYLNIVGFTLLFYGSVIGMIMFRDYLTYDGA
                     GSLISTFILVSGTYHSVKSTFPYEGKRHPTFILTPYYLFKHLLLSVTKVYAFQIRVVT
                     IGIICLAIAFPEQLVWIALSVLAVFIYWLSLPLVAIFRVAGRLLNLLMIYGMYLNQEL
                     LVIACLCLNVVILVLSVTINVHYPYQWLAVRARKEEKTITLLKLVINTITDHLALMVL
                     FSIFCIAVTYFTQRLLLSFDYSSFSIPVFFLSASTYIALLEVMVGKNIKELELDRGLA
                     VLQFLNRDISVYKAYRNSQFLLSAHILAVIHTGCAIGLLPFLLNGQAALFLSNLVMIP
                     FIYFISFCYFVKSLKIVAGDLSVFRWVILVLYFILVVIAMVGSRL"
     gene            3409..3891
                     /locus_tag="TV188_001439"
     CDS             3409..3891
                     /locus_tag="TV188_001439"
                     /inference="COORDINATES: protein motif:HMM:NF014052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HEL1534781.1"
                     /translation="MIMRKFLRYYISFIIFSIAIGILIGLLITSDTVILSKPERGWDF
                     TLEVLKNNSNNFLSYIFLFFLSPALQLIDLVSVVIQITLGMRKSGFLITALGLFPHGL
                     LEIPNFLFYQGLSQYMLWTVLTEKSMTSFLERERRYVRYYLISYYVLLIAGIMEGLLG
                     "
     gene            3888..4475
                     /locus_tag="TV188_001440"
     CDS             3888..4475
                     /locus_tag="TV188_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1534782.1"
                     /translation="MKIVNESKSFSNRKILNHISFDFSKGLYKVEGNNGSGKTTFLRL
                     LAGLERFDSGHRLQHKGDILYLDTNAIGVVPLTIEDNLTLLWKTFNASPDEETLSVIN
                     QFFGERLLDHYLTASVGTKAKVGLSLLFVKDWDYIFIDEALSTLDGFSLDMVAGRLLA
                     LKEKATVFYVSHNLSHQQLLSESQVIYLNGKGEIY"
     gene            4472..4954
                     /locus_tag="TV188_001441"
     CDS             4472..4954
                     /locus_tag="TV188_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534783.1"
                     /translation="MKGNPFNRNLSWLIAYVLLLSCYVFILVDGGFLKNSVQELEVLL
                     GQTSLAIKLFLMVISIAFSIISLLVEYFLSKFLVLLFIEAGIVSLNDVLTAKSVTLVI
                     HLSALLLKLSPSPLFQFVVNALGIVIMYGLSIKRQGNRTTALLFCLPFTLDILATLLL
                     "
     gene            4979..5494
                     /locus_tag="TV188_001442"
     CDS             4979..5494
                     /locus_tag="TV188_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534784.1"
                     /translation="MKKILYLSVLLGTSILATLIKIYNTFFAKLKASSGHSTGNIEID
                     ALLSESRLVLERQHAFTTNGINKLFVMMMSLMLLLALYYLIKKDLKAVYSYLLYLVLT
                     LVHAIYSFFSLSPLAKLYSDDMLGATIQTGEKAKLIFSVVLFLLYLLIVVANNRVKSS
                     VEPASSIGIDV"
     gene            6128..7762
                     /locus_tag="TV188_001443"
     CDS             6128..7762
                     /locus_tag="TV188_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534785.1"
                     /translation="MTRFFQKKQAKSLAIGFVSLFAVLIGYGAFHYSKASRINAYLQA
                     RSSGSGQVLENIKEYLVWADTNEQLTNDQARYTSFKRYSKAELVSKRQQLQTATAADD
                     MYVKSVGRKFLIFPDYRIAVKPVALTIKTNVPNVDILLNHKKIAVSQSEDFSTTIERL
                     PAADYKASINGYYKDRKIKVSKAYDGKNHTLDLRVTFKTFTVTSNVRDGELYIDGERV
                     ETLKAGQLQLEEYPVTEIAKAYIKKTFPDGELTSSKHSLAPVAEGSQLEINIDHLLTE
                     EQAGQVLVAAFDQLLTYLNQGQDPAGLSTVFEQGANNAFYKGLKDSIKAKFQTDTRKA
                     SRLSIPSILLSKLTQIGKQSYLVDFTAVYDFVYDKETDPEKGTSGNVRQDLTGKLTLK
                     KSGDSYLVSQSGPKNITVASEKNQVKPSIFPEGLVGTWIGHRSDMTFTMILAKDGSIT
                     TTIGNKNGNGSQTTKSAKITKVEEKGDGLFLYTVAPDADIAALVPGGGLGGVNVKYAF
                     GVKWSGDVATIVVWQTANNAAFDYSKPMLGPDMKKQ"
     gene            complement(7903..8796)
                     /locus_tag="TV188_001444"
     CDS             complement(7903..8796)
                     /locus_tag="TV188_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEL1534786.1"
                     /translation="MTTANKPEMGFQISFINPYQATTVKELLEDRLLIPRKIRHFLRI
                     KKHVWVNDELINWQSPVKQGDHIKLQFDQEDYPDKGILMGKPGLVDCLYQDEHLIIVN
                     KPEGMKTHGNEPTELALLNHVSAYTGKTCYVVHRLDMETSGAILFAKNPFILPILNRL
                     LEHRDIKRDYWALIEGQLEQQTVTYRDPIGRHRHDRRKRVVDSKHGQEAITHLALLQA
                     FDQTCLVNCRLETGRTHQIRVHLAHHKHPLIGDPLYSRQKAERLMLHAHQLTLRHPLA
                     QEMIRVTAPSKSFKEGLQQLN"
     gene            complement(8780..8971)
                     /locus_tag="TV188_001445"
     CDS             complement(8780..8971)
                     /locus_tag="TV188_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534787.1"
                     /translation="MNKFQAFKETLSAESLKAVYDETRLEVASDEREGTEAFSVTLAT
                     QMAINLIEKYHDWLNDNSK"
     gene            9206..10960
                     /locus_tag="TV188_001446"
     CDS             9206..10960
                     /locus_tag="TV188_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein"
                     /protein_id="HEL1534788.1"
                     /translation="MNKPLIKSCLLALLTLAGLTSMAAQADVNTYNQGRTYNDTPYYS
                     AYHHYYDHTRDTADNGIDNWGRLTRYHYYRETYYQLEAERQQLVRTYLELKASYDDQV
                     ALSSQRLQQYQSGWSDLQSRFEQLRKTNPVVGGDYRIVELEGNFQSYQTLLQQLSMAD
                     FVSQYKDRLDTLTRLDTERARLIDTWWESDSNYSDLNTNLTLVNGYIKELNQALQELL
                     KDHQGKMTSDLQTLGDRQAELARRLTDIESRPKRQATSQPRGSQTHWRSAPRADVALW
                     NELRNEGDYASATTDNALPLQPYRADLTAVHDLEALQAQSDRAHRLRAKEIVFTLQRS
                     NISRQGDIDLSGAITAFIKEKLLVTPNARGVSSGFRWQMQTYDNERLTITLMPQYYMT
                     DDQYKEYYDHLKAWTAQHIQSTDTEVEKIDKIQDYIMTNYHYATGKVGGVTRTGISVQ
                     TPYAFIKDKEAVCQAYAQMFKDMGRLAGLDVHYIQGYGDPVGGLSSLHAWNIVKVDGQ
                     YYHIDLTWNDTIDSTNHNHTYTLRGNDFMSKTHLWNAAYAISDSDYAAYPRRSFLRYG
                     TYATNYSRNTFYPGYSYA"
     gene            11101..11481
                     /locus_tag="TV188_001447"
     CDS             11101..11481
                     /locus_tag="TV188_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEL1534789.1"
                     /translation="MKSIRRYDVNEEWAHTGLVEAGDFYFLNYCVGNVGQDIEAQING
                     AFDEMERRLGLVGLTLEVVVQMDCLFRDIWNVPVMEKIIKERFNGKYPARKFLQTAFA
                     HQGGPDGLLFQVDGVAYSKHISVS"
     gene            11519..13852
                     /locus_tag="TV188_001448"
     CDS             11519..13852
                     /locus_tag="TV188_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEL1534790.1"
                     /translation="MTFLELLQKKFFPKKYQEKQALKERAAQHMADKEATTQATATAL
                     ADQEAQAGQTERQSVLQRSKSYGVKRKNRPIWLQRLEAILPSQQGPIRRFLRRYHVGK
                     ILLILMGTFVLLLGSYLFYLSKTAKVSDLQDALKATTVIYDRKGEYAGSLSGQKGTYV
                     ELDAISDDLEKAVIATEDRTFYTNNGINFKRFLLAIVTAGRFGGGSTITQQLAKNAYL
                     SQEQSIKRKAREFFLALELTKKYSKNDILTMYLNNSYFGNGIWGVEDASQKYFGTSAA
                     NLTLDEAATLAGMLKGPEIYNPYYSIEKATNRRDTVLSAMVDAGKISKQQAQEAQAIG
                     MGNRLADTYVGKTDDYQYPSYFDAVINEAISRYGISEKDIVNDGYKIYTELDQNYQAG
                     MQTTFNEDSLFPVSEFDGSSAEAASVALDPKTGAVRGLVGRVNSTENQPFRSFNYATQ
                     AKRSPASTIKPLVVYTPAVAAGWSLEHELPNSVQDFGGYQPHNYGNYESETIPMYQAL
                     ANSYNIPAVSILDQLGVDKAFSYGEKFGLKMSETKKELGVALGSGVTTNPLEMAQAYA
                     VFANGGVKHIAHLITRIENAKGKVIKTFTDKTKRVISQSVADKMTSMMLGTFSNGTAV
                     NANVYGYTLAGKTGTTETDFNPDLSGDQWVIGYTPDVVISQWVGFNQTDEHHYLSDSS
                     AGTASAIFSTQASYILPYTKGSQFKVDNAYAQNGISAVYGINETNTQAGIDSQSIIDS
                     LRKSAEEASKSISEAVDQSGLREKAQSIWKSIVDYFR"
     gene            13901..14053
                     /gene="rpmG"
                     /locus_tag="TV188_001449"
     CDS             13901..14053
                     /gene="rpmG"
                     /locus_tag="TV188_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEL1534791.1"
                     /translation="MAQKKASLACVECGSRNYSIGISSTPRPTRLEVNKFCKYCKAYT
                     LHKETR"
     gene            14065..14241
                     /gene="secE"
                     /locus_tag="TV188_001450"
     CDS             14065..14241
                     /gene="secE"
                     /locus_tag="TV188_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002982348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEL1534792.1"
                     /translation="MGFISGIFKLLRDTTWPDRKQRWKDFISVLEYTAFFTVIIFIFD
                     QLLSKGILSLINLF"
     gene            14632..15177
                     /gene="nusG"
                     /locus_tag="TV188_001451"
     CDS             14632..15177
                     /gene="nusG"
                     /locus_tag="TV188_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEL1534793.1"
                     /translation="MLDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEI
                     PTQTVNVEKNGQVKEVEENRFPGYVLVEMVMTDDAWFVVRNTPNVTGFVGSHGNRSKP
                     TPLLEEEIRAILLSMGQTVDVFDTNIKEGDMVQIIDGAFIGQEGRVVEIENNKVKLML
                     NMFGSETLAEVELYQIAELSS"
BASE COUNT         4566 a         2904 c         3514 g         4908 t
ORIGIN      
        1 tcaaggcttt tgcaggagat ttatgaaaaa gaaaaattta ggatagtgta agtataagct
       61 agtttcctta agaaaagctt aactgaagca attaatcgta gagatgggtg attgttttga
      121 cgactttttt ctccttgtca gaccaataat gaaggcgttc aaaagatcct tgtcgccagt
      181 agagtggtag cctttgtcga atatcctctt gcatgtctag cttatctaga tcagcaatag
      241 catgccattg tggtaggccc tctcgtgatt tagttagcag cttgccttca aaatcttcgc
      301 aaagaaagtc ataataaaca tagcgctcag gcttatcagg attggtaaag cctgagattc
      361 cctttaattg cagatttaag gcggttaagc cggtctcctc ctttagctca cgcactgccg
      421 cttcaaaaaa ggattctgag gtgttaacct tgccacccgg ttggatccag ccaggaaaat
      481 cgtcatgctg gcggttgaga agtaggatct tgtcgccctc cttgacacag atattaaccc
      541 aatttttgat gacttcaagc attagttacc tcgtttttag ttttatttta tcaaaaaaag
      601 atcagtatga atagctgaga gatttattga tatggtcata atggcttcag atagttttac
      661 tgctgcttta gccatctgca taaataatat aaaaatacca tttcacatca ttatttaata
      721 gatttattat catattaatg gtataattat gtgaaattag aactatgtgt agagagagta
      781 taatgaatag tacagatttg atgagactgg gagagcttta taaggagctt cgtattgctc
      841 gtggacttag gctaaaggac gttgctagag acaatttatc agtttcacag ctatctaagt
      901 ttgaaaatgg ccagagcatg ctggcagctg acaaactact attagctatt tcaggaatcc
      961 atatgacatt cgctgaattt ggtcatgctg taaatgggta taaagtcagc gatttttttc
     1021 agttaggcac caaggttgcc gagctacaaa cagcatcaga tatagatgga ttgaaggagc
     1081 ttctgagcca atataagggt gatgacattt tttctgttta taatagatta aatgaattaa
     1141 tcattaaaag tgctatctac tcacttgatc caaatgttaa aattgaagaa tcagacaagc
     1201 aattgttgac agaatacctt tatagtattg aagagtggac ggagtatgag ctatacattt
     1261 ttggcggttg tttggctatt ttatctgatg aggatatgat ttttttggga aaagcattta
     1321 tcgaacgaga taagattttc ctttctcttc cacaacatag aaaggcagct cacatcactc
     1381 tcttaaatat tatcatgaca aggcagcttt ttatgttgat ttttttatta aaaagctgga
     1441 ggagttgatt atctatcaag atatgttcac tatagtgagc ttaaattttt ttaagaaaat
     1501 atatacctac ttaaatgaag aaagtaagca taagagcgac attgaagatt atattaatct
     1561 tgttaaacag cttggcaacc ctcagtttgc ccaaattcta catcggacgc tatcagtgat
     1621 tctagatagt taatactaaa aaagtagccc aatcgtttgg tggctacagt ggccaaggcc
     1681 accaaataga caaaagggct aataagaaaa taaaagcttt tcgcataata tctcacctcc
     1741 ttgataagga tattatacaa aggggaagct tcaatctcaa acattcgcaa atatgaaaat
     1801 attaacaaaa gcatcatcat atttgcgaat atcgagaata tgataattgt cgtgatataa
     1861 ttactgtgtt aatgatttag ctaggcatta ataaatctaa atatagacta caggcaggtc
     1921 gctcgttata ctagtttgag ggccaatggt ctgggtagga ggaagcgtat ggcgacatta
     1981 gagcgacatc ataaaatgtt attattgtca atggcattag gggcagcgag ctggttagca
     2041 ctcggattga ttagcttgcc aaatcttgca ggtgctttag gaataagtac tgctaatgcc
     2101 aatactacag ttaatttgtt gagtgcttat agtacagttt ctagcgttgt tgcaatcgtt
     2161 ggtgctgtta cgggtgtagg gtctattgga gctggaattg cagctaccgt tttatacctt
     2221 atcaaacaaa aaggaaaggc tgctgctgct ctctggtagt taattgtctg atatgaagca
     2281 tgttttcaaa tatcataaag gcgacatttt agggtatctc aatattgttg ggtttaccct
     2341 tttgttttat ggctcagtga taggtatgat aatgttcagg gattatttga cctatgatgg
     2401 agctggttct ctaatatcga cctttattct ggtatcagga acctatcatt ctgtgaaatc
     2461 aacatttcca tatgaaggga agcgtcatcc aacttttata ttaacaccct attatctatt
     2521 taagcatcta ttgctttcag ttacaaaggt ttatgctttc cagatccgag tggttactat
     2581 aggaatcatc tgtttagcaa tagcctttcc ggagcagctt gtttggatag ccttgtctgt
     2641 gctagcagta tttatatatt ggctatcgct tccgctagta gccatttttc gagtagctgg
     2701 acgactcctg aatcttctca tgatttatgg tatgtatctt aatcaggagc tgctggtcat
     2761 tgcttgtctt tgtttaaatg tggttattct tgtgcttagt gttacgatta atgtacatta
     2821 tccctaccaa tggctggcgg tgagagctag gaaggaagaa aaaacaatta ccttgttaaa
     2881 gcttgttatc aatacgataa cagatcattt agctttaatg gttctgttta gtattttctg
     2941 tatagctgtg acctatttca cgcaaaggct gctgctaagt tttgattatt ctagctttag
     3001 cataccagtt tttttcttat ctgcttctac ctatatcgcg ttactagagg ttatggtcgg
     3061 taaaaatatt aaggagcttg agttagaccg gggcttggct gttttacagt ttctgaatag
     3121 ggatatcagt gtttacaaag cttatcgcaa cagccaattc ttgctttctg ctcacatctt
     3181 agctgttatt catacaggat gtgccatagg cttactacca tttttactaa atggtcaagc
     3241 tgctcttttt ctgtctaacc tagtgatgat ccccttcatc tactttatat cattttgcta
     3301 tttcgtgaaa tcactaaaaa tagttgctgg tgatttgtca gtgtttaggt gggttattct
     3361 ggttttgtat tttatactag tggtcattgc aatggtaggt agtcgtttat gataatgagg
     3421 aaatttttaa gatattatat cagttttatt attttctcaa tagcaattgg gattttaatc
     3481 ggtttgctga tcaccagtga tactgtcata ttatctaagc cagagcgggg ctgggatttt
     3541 actctggagg ttttgaagaa taatagcaat aattttttgt cctatatttt cctcttcttt
     3601 ttgtccccag ccttgcaatt gattgatttg gtatcagttg ttatacaaat tactctagga
     3661 atgaggaagt ctggatttct aataactgcc ttgggtttgt ttccgcatgg tttgctggag
     3721 atccctaatt ttctctttta tcaaggcttg agtcaatata tgctatggac tgttttgact
     3781 gaaaaaagca tgacgtcctt cttagaaaga gaaagaagat atgtaaggta ctatcttata
     3841 tcgtattatg ttttgttaat tgctggtatt atggaagggt tactcggatg aaaatagtaa
     3901 atgaaagcaa gtcattttca aacagaaaaa tcttaaatca catatccttt gactttagta
     3961 aagggctgta taaggttgaa gggaataatg gtagtggtaa aaccactttt ttgcgcttgt
     4021 tagcaggctt agaacggttt gatagcggcc atcgcttaca gcataaggga gatattctat
     4081 atcttgatac taatgctatc ggtgtagttc ccttaactat tgaagacaat ctgacattat
     4141 tatggaaaac ctttaatgcc tctcctgatg aggagacctt gtctgtgatt aatcagttct
     4201 ttggagaacg gttactagat cattatctga cggcttctgt aggaacaaag gctaaggtgg
     4261 gcttatcctt gctttttgta aaggattggg attatatttt catagacgaa gccctatcaa
     4321 cgcttgatgg gtttagtctt gatatggttg caggaagatt attagcatta aaagaaaagg
     4381 ctactgtttt ttacgtttct cataatctat cacaccagca gctattgtca gaatcacagg
     4441 tgatttatct taatggaaaa ggagaaatct attgaaaggt aatcctttta atcgtaatct
     4501 ttcttggtta atagcctatg tgctattact ttcttgttat gtattcatat tagtagatgg
     4561 tggtttttta aaaaacagcg ttcaagaatt ggaagtcctg ctcggccaaa catcactagc
     4621 tataaagctg tttttgatgg tgatatcaat agcttttagc atcatatctt tactggttga
     4681 gtatttttta agcaaatttt tagtgctgct ttttattgaa gctggcatcg tttctttaaa
     4741 tgatgttctt actgctaaat cagtgacttt agtgatccat ttatctgctt tgctattgaa
     4801 gctatctccc tctccacttt ttcagtttgt agtgaatgct ttagggattg tgatcatgta
     4861 tggattgagt atcaagagac aaggaaatag gacaactgct cttttgtttt gtttaccctt
     4921 tacactggat attctagcaa cattgttgct ttagtgattt tgagttggag gaaaagtaat
     4981 gaaaaaaatc ttatatttat cagtactttt aggaacgtca attctagcaa cattgattaa
     5041 aatttataac actttttttg caaagctaaa ggcttcatca ggtcattcaa ctgggaatat
     5101 agagattgat gcccttttat ctgagtctag actagtgttg gaaaggcagc atgccttcac
     5161 aacaaatgga atcaacaagc tattcgttat gatgatgagt ctaatgctgt tattagcctt
     5221 atactatctg ataaaaaagg atttgaaggc cgtctatagt tatttgcttt acctggtgtt
     5281 aaccttggtt catgcaattt atagcttctt ttcgttaagt cccttggcaa agctttattc
     5341 tgatgatatg ctgggggcta caatccagac gggagagaaa gctaaattga ttttttcagt
     5401 ggttcttttt cttctttatc tgcttattgt tgtggccaat aatagagtaa aatctagtgt
     5461 agaacccgct tcatctattg ggatagatgt gtaatacctt tcatattatg acctttaaag
     5521 ccttttagct tctctaattt tcagagtaac taggaggctg tttgtgacgc tctgagcgtt
     5581 ttttcgtttc tatcaaagtt tagctgcgtt aatgctatct atttccgtag ctgagataca
     5641 agatattata atatgtgttg tcataccata aaaacacctt acaggatatt ttatgatcaa
     5701 tcctccttga attaagcttt ctttaagcaa gggtgtgtat actagccgta atcctaaata
     5761 attggttacc taatgataac taattttttc ataacctcct tcctaaaaac gatgtcaggg
     5821 cagtcaggat tgattgctgt tatggcatcg tttttgttgt actttgatag gggatctagc
     5881 tgtatgttaa atagcctatc aggattgagt ggcgaagatg atcaggagtc tcttggctct
     5941 aggttatgct gctgtttcat gagaaacagc tcttgatgat caatttaggt agtattagtg
     6001 gtggtcatct tagcctttta ggctttgagc tgctttatgt ttgctcattt ttaatatgtt
     6061 agtgtttaca caaataattc tcattttttg atataataga aaaggtaagg aagggtagga
     6121 gataaggatg acaagatttt ttcaaaaaaa acaggccaaa agcttagcca ttggttttgt
     6181 gagcttgttt gctgtgctca ttgggtatgg agcttttcac tattctaagg ccagtcgtat
     6241 caatgcctat ctacaagcaa ggtcatcagg ctctgggcag gtgcttgaaa atatcaagga
     6301 atacctcgtg tgggcagata ccaatgagca gctgaccaat gatcaagcaa gatacaccag
     6361 ctttaagaga tacagtaagg cagagctagt aagcaagcgt cagcagctgc aaacagcaac
     6421 tgcagctgat gatatgtatg tcaaatcggt tggtcgcaaa tttttgattt tccctgatta
     6481 tcgcatagca gtgaagcctg tagccttgac aatcaagacc aatgtgccaa atgttgatat
     6541 cttgttgaac cataaaaaga ttgctgtatc acagtcagag gattttagca caactattga
     6601 aagactgccg gctgctgatt ataaggcgag tattaatggc tattataagg atcgtaagat
     6661 taaagtcagc aaggcctatg atggcaagaa ccatacacta gatttgaggg ttacctttaa
     6721 gacatttacg gtaaccagca atgtcagaga tggcgagctt tatattgatg gcgagcgcgt
     6781 ggaaactttg aaggctgggc agcttcagct ggaagaatac cctgtgacag aaatcgcaaa
     6841 ggcctatatt aaaaagacct ttcctgatgg cgagctaacc tccagcaagc attcccttgc
     6901 tcctgttgct gagggctccc agctagagat taacattgat cacctcttga ctgaggaaca
     6961 ggcgggacag gtgttggtgg cagcctttga tcaattgctc acctatctca atcaagggca
     7021 ggatccagca ggtctttcaa ctgtttttga gcaaggggct aataatgctt tttacaaagg
     7081 cttgaaggat tccatcaaag caaaatttca aactgatacc agaaaggctt ctcggttaag
     7141 cattccgtct attttgttaa gtaagctaac tcaaattggt aagcagtctt atctagtgga
     7201 ctttacagct gtttatgatt ttgtttacga taaggaaact gatcctgaaa aaggcacctc
     7261 agggaatgtt cgtcaagact tgactggtaa gctgaccctg aaaaaatctg gggatagcta
     7321 ccttgttagt cagtctggtc ctaaaaatat tacagttgcc agcgaaaaaa atcaggtcaa
     7381 gccgtctatt ttcccagagg ggctagtggg aacctggata ggacatcgtt cggacatgac
     7441 ctttacgatg atattggcta aggacggcag catcacaaca accattggaa acaaaaatgg
     7501 gaatggctca cagaccacta agtctgctaa aattaccaag gtagaggaaa aaggagatgg
     7561 cttgttcctc tacactgtag ctccagatgc tgatatagca gctcttgttc caggaggtgg
     7621 attgggtggt gtcaatgtca aatacgcttt tggtgtcaaa tggagtggag atgtcgctac
     7681 gatagtggtt tggcagacag caaataatgc ggcatttgat tacagtaagc caatgcttgg
     7741 ccctgacatg aaaaagcaat aagtacttta ccctacaagt tggtctagca tttattgcta
     7801 ggaggaatca gcataaagaa aaagcctctc ttttaatctt ttgtggttaa gaagagaggc
     7861 tttttagtat agggctgact gtatgaggag caaccgatgt aatcaattta gctgctgtag
     7921 tccttcttta aagcttttag acggggcagt gaccctaatc atctcttgag ccaaggggtg
     7981 tctaagggtt agctgatgag cgtgcagcat gagacgctcc gctttttgcc tgctatagag
     8041 gggatcacca attagagggt gtttatgatg agcgagatgt actctgattt gatgtgttcg
     8101 tcctgtctct aggcgacagt tgactaggca ggtctgatca aaggcttgta ataaggctag
     8161 atgggtgatt gcctcttgcc catgcttact atcaaccaca cgcttgcgcc tatcgtggcg
     8221 gtgacgtccg attggatcgc gataggttac tgtttgctgc tctagctgac cttcgattag
     8281 ggcccaataa tctcgcttaa tgtctcgatg ctccaatagg cgatttaaga tcggaaggat
     8341 aaagggattt ttagcaaaga gaatcgctcc actagtctcc atgtctaagc gatgaaccac
     8401 atagcaggtc ttgccagtat aggcagagac atggttgagc aaggcgagct cagtgggctc
     8461 attgccatgt gttttcatgc cctcgggctt gttgacaatg atgaggtgtt cgtcctgata
     8521 caggcaatcc actaggccag gcttacccat taagatgcct ttatcagggt agtcttcttg
     8581 gtcaaattgt agcttgatgt gatcaccctg cttgacaggg ctctgccagt taatcagctc
     8641 atcattgacc caaacatgct ttttgatgcg caagaaatgt ctgattttac ggggaatcaa
     8701 tagcctatct tctaataact ccttgacagt tgtcgcttga taggggttaa tgaaggagat
     8761 ctgaaagccc atctcaggct tatttgctgt tgtcattgag ccagtcatgg tatttttcaa
     8821 tcaaattgat ggccatttgg gttgcaagag ttacagagaa agcctcggtt ccctcgcgct
     8881 cgtcactggc aacctctaag cgtgtctcat catagacagc cttgaggctc tctgctgaca
     8941 gggtttcttt aaaagcttga aatttgttca tgatcatgtc ctacctttct aaatgtttgt
     9001 gacaatgcta ttatagcata tttttcatca aagctaatca tttgctcgat gatttgtgct
     9061 gcgctaacag cgtgattctt ttgagaaaaa ataagattag ctattgtgaa attgtctgtc
     9121 ttttattata ctaagaatag tctgataaat atattattta aggacacgat aacattggga
     9181 ttatgaatca tttaggagaa tactattgaa caagccattg ataaaatcct gtttgcttgc
     9241 tctattgacc ttggccggct tgaccagtat ggcagcacag gctgatgtca acacttacaa
     9301 ccaaggtagg acatataacg atacacccta ttattctgct tatcatcact actatgacca
     9361 cacgagggat actgctgaca atggtattga taattggggt cgtctgacac gctatcacta
     9421 ttacagagag acctattatc agcttgaggc cgagcgtcag cagcttgtta ggacttactt
     9481 ggagttgaag gcttcatatg atgatcaggt ggctcttagc agtcaacgac tacagcagta
     9541 ccagtctggc tggtctgatc tccaatcacg ctttgagcag ctcaggaaaa ccaatcctgt
     9601 tgtaggcggt gattatcgga ttgttgagct agagggcaat tttcaaagct atcagacctt
     9661 gctgcagcag ctttctatgg ctgattttgt cagccagtac aaagataggc tggatacctt
     9721 gactagactt gatacagagc gagctaggct cattgacacc tggtgggaaa gtgatagcaa
     9781 ttactcagat ctcaatacca atctaacact agtcaatggc tatatcaagg agctgaatca
     9841 ggctttacag gagcttctta aggaccatca aggtaaaatg acatcagatc tgcagacctt
     9901 gggtgaccga caggccgagc ttgctagacg gctgacagat atagaaagca ggcctaagag
     9961 acaggctacc agtcaacctc gtggttcaca gacacattgg cgatcagccc ctagagctga
    10021 tgttgccttg tggaatgaat tgcgaaacga aggagattat gcttctgcta cgacagacaa
    10081 tgctttgcca ttgcagcctt atcgagcgga cttaacagct gttcatgatc tagaagcctt
    10141 gcaagcacaa tctgatagag cacaccgctt gcgggcaaag gaaattgtct ttacactgca
    10201 gcgttctaac attagtcgtc agggcgatat agatttgtca ggagccatta cagcatttat
    10261 caaagaaaag cttctcgtca ctccaaatgc gcgtggggta tcatctggct ttaggtggca
    10321 aatgcaaacc tatgacaatg agcgcttaac catcactcta atgcctcaat attatatgac
    10381 tgatgatcag tacaaggagt attacgacca tctcaaggct tggacagctc agcatatcca
    10441 gtctaccgat acagaggttg agaaaattga taagattcaa gactatatca tgacaaacta
    10501 ccactatgcg accggcaagg ttggaggagt gacccgtact ggcatttctg tgcagacgcc
    10561 atatgccttt atcaaggaca aggaggctgt ttgtcaggcc tatgcacaga tgtttaagga
    10621 catgggacga ctagctggac ttgatgttca ttatattcaa ggctatggag acccagttgg
    10681 cggcttatca agtctacatg cttggaatat cgtcaaggtt gatggtcaat attatcatat
    10741 tgacctgact tggaatgata ctattgacag caccaatcac aatcatacct acaccctgcg
    10801 aggcaatgat tttatgagca aaacacattt gtggaatgct gcctatgcga tctcagatag
    10861 tgactatgct gcttatccta ggaggagctt cctgagatat gggacctatg cgactaacta
    10921 ttcaagaaat acattttatc caggatacag ttatgcttaa taatagctaa taccatcaaa
    10981 agccctagaa agcttgcttg attctttcag ggctttttga tatgtcatgg tttttggtat
    11041 aggattttga aagaaattgt tataatagga taaaatgctt atgtaacagg agaaaataaa
    11101 atgaagagta ttagacgcta tgatgtcaat gaagagtggg cacatactgg cttagtagag
    11161 gcaggcgatt tttatttttt aaattattgt gtaggaaatg tcggtcaaga tattgaggct
    11221 caaattaacg gtgcctttga tgaaatggag cgtcgtttgg ggctggtagg gctgacgcta
    11281 gaggtcgttg ttcaaatgga ttgcttgttt agagacattt ggaatgtgcc agttatggaa
    11341 aaaatcatca aggagcgatt taatggcaaa tacccggctc gtaaatttct tcaaacagcc
    11401 tttgctcatc agggtggtcc ggacggcttg ctatttcagg tagatggggt tgcttattca
    11461 aagcatatct ccgtatccta aacaatatga cttggaggct tagtagtatc ataaggctat
    11521 gacattttta gaattattac aaaagaaatt ttttccaaaa aaataccaag aaaaacaggc
    11581 cttaaaggaa agggcagccc agcatatggc tgacaaagag gctactactc aggctactgc
    11641 cactgctttg gccgatcagg aggcacaggc agggcagact gagaggcaat cagtccttca
    11701 acgcagcaag tcctatgggg tcaaaaggaa aaatcggccg atctggcttc aaaggctgga
    11761 ggcgattttg ccatcgcagc aaggtcctat tcgccgcttt cttcgtcgtt accatgttgg
    11821 taaaatcctg ctgattttga tgggtacctt tgtcttgctg ctggggtctt acctttttta
    11881 cctttcaaag acagctaagg tttctgactt gcaggacgct cttaaggcga cgacagtcat
    11941 ctatgaccgc aagggagaat atgcaggcag tctttctggt caaaagggga cctatgtgga
    12001 gcttgacgct atttcagatg atttggaaaa ggcggttatt gccacagagg accgtacctt
    12061 ttataccaac aatggtatta atttcaagcg ctttttattg gctattgtga ccgcaggacg
    12121 ctttggtgga ggctcgacca ttactcagca gttggctaaa aatgcttatt tgtcccagga
    12181 gcagagcatt aaaagaaagg cgcgtgagtt tttcttagca cttgaattga ccaagaaata
    12241 cagtaaaaat gacattttga ccatgtatct caataattcc tattttggaa atggtatttg
    12301 gggtgttgag gacgccagtc aaaaatattt tggtacctca gcagctaatc taaccttgga
    12361 cgaggcagca acccttgccg gtatgctcaa gggacctgaa atttacaatc cctattactc
    12421 aatcgaaaag gcaaccaacc gtagagatac tgttttgtca gccatggttg acgctggaaa
    12481 aatcagcaag cagcaggcac aagaggccca agctattggt atggggaacc gtttagcaga
    12541 cacctatgtc ggcaagacag atgattatca gtacccatct tattttgatg ctgttatcaa
    12601 tgaggctatc tcgcgctatg gcatctcaga aaaggatatt gtcaatgatg gctacaagat
    12661 ttacacagag ttggaccaaa attaccaagc aggcatgcag accaccttta atgaggatag
    12721 cctatttcct gtgtctgagt ttgacggcag ctcagctgag gcggctagtg tggctctaga
    12781 tcctaaaacc ggagctgtca gggggcttgt tggtcgtgtc aatagcacag aaaaccagcc
    12841 ctttagaagc tttaactatg ctactcaagc caagcgtagc cctgcttcaa cgatcaagcc
    12901 cctagttgtt tatactcctg ctgttgcagc aggctggtca ctggagcacg aactgccaaa
    12961 cagcgttcag gattttggcg gttatcagcc gcataattat ggcaattacg aatcagaaac
    13021 aattcctatg tatcaggctt tggctaattc ctacaatatt cctgctgttt caattctgga
    13081 tcagttgggg gtggataagg cctttagcta tggtgaaaaa tttggtttga agatgagtga
    13141 aaccaaaaag gagcttggag tggcgcttgg tagtggtgtc accaccaatc cgcttgagat
    13201 ggcacaggcc tatgcagtct ttgccaatgg tggtgtcaag catattgccc acctgattac
    13261 cagaattgaa aatgctaagg gcaaggttat caagaccttt acagacaaaa ccaagcgggt
    13321 tatcagtcaa tcagtggctg ataagatgac tagcatgatg cttggaacct tttctaatgg
    13381 tacagctgtt aatgccaatg tctatggcta tactctggct ggtaaaacag ggaccacaga
    13441 aactgacttt aacccggacc tttccggtga tcagtgggtc attggctaca cgccagacgt
    13501 tgttatcagt caatgggttg gcttcaatca aaccgatgag catcattatt tatcagattc
    13561 aagtgcgggc actgcctcag caatttttag cacccaagcc tcttatatat tgccatatac
    13621 caaaggaagc caattcaagg tcgataacgc ttacgctcaa aacggtattt cagcggttta
    13681 tgggattaat gagaccaata cgcaagcagg tattgattct caatccatca ttgatagtct
    13741 tagaaagtca gccgaggaag cttcaaagtc tatttcagag gcagttgatc aatctggtct
    13801 cagagaaaag gcgcaaagta tctggaagag tattgttgac tactttagat agcttgcgaa
    13861 aatatctaaa tcgtgttaga ataatcacta cggaggcgtt atggcacaga aaaaagcaag
    13921 cctagcgtgt gtagaatgtg gcagccgcaa ttattctatc gggattagta gcacgcctag
    13981 accaacacga ctagaagtca ataagttttg caaatattgt aaagcataca ccttacacaa
    14041 agaaacacgt tagaggagag cctgatggga ttcattagtg ggatttttaa gcttttaagg
    14101 gatacaactt ggccggatcg taagcagcgc tggaaggact ttatttctgt ccttgagtat
    14161 acagcattct ttacggtaat catctttatc tttgaccagt tgctatcaaa aggcatttta
    14221 tcattgatta atttattcta agtcattgca atgatgagac ctgttatgat taaaattgct
    14281 tggaaaagcc taggctgaaa caatcgtttc ggcctttttg agtgcgatgg gcaggttgta
    14341 ctctgataga tgcaagacca atagaccacc tactatgcgg gtgcgtaaag gggttgatag
    14401 ctaccgatag ttaagggcta tagcaagtag aaaggcttgc agctcagctg atccgctgtt
    14461 atgactaaag gcattgacca gaaaggttcg ttggcagcca acaaagtgct cttaccctgc
    14521 tatgaggggc tattaatgcg ttgacagcca atccttcttc tattataatg aaagtgtgat
    14581 aacagcaatg caaaggccag cagaggcttt tttataatga aaggaagtaa catgttagat
    14641 tcttttgata agggctggtt tgtccttcaa acttactcag gctatgaaaa taaagtaaaa
    14701 gaaaaccttt tgcagcgtgc tcaaacctat aacatgctag acaatattct ccgcgttgag
    14761 attcctaccc aaacggtaaa tgttgaaaaa aatggtcagg tcaaagaggt tgaggaaaac
    14821 cgcttcccag gatatgtttt ggttgagatg gttatgactg atgacgcttg gtttgttgtt
    14881 cgtaacacac caaatgtgac aggctttgtc ggatcgcatg ggaaccgctc aaaaccaacc
    14941 cctctacttg aagaggagat tcgtgctatc ctgttgtcaa tgggacaaac tgttgatgtc
    15001 tttgatacca acattaaaga gggcgatatg gttcaaatca ttgatggcgc ctttatcggg
    15061 caagagggtc gtgtcgtaga aattgaaaac aacaaggtca agctcatgct taatatgttt
    15121 ggctcagaaa ccttagcaga ggtcgagctt taccaaatcg cagagctatc gtcctgatag
    15181 gctcctaaag ctattattca taccataaaa aataaaaggc tggcatcggc tctctaaaat
    15241 accgatgtta ggcctttttt gttggtcttc tacaaccaag actcaaatta accaaaccct
    15301 aaaaagagtc atttttcctt cgctttttaa gtctctaact gatcgcccta gcttattttt
    15361 aatctagtaa tcgcaacagg tcaagagtta aatgatatcg cgccgttatt gattggtata
    15421 gacaaaaata cgctcaaaaa aagaaaaaag gataggtaat atagtcctgg tttgcttgat
    15481 agatggtggt tggcaaccaa ccattcgagt actttcctta actataaact cctaatcaat
    15541 tctagcgttt aaaaaataag attattcttg gagggaagca aagagcttct ctcctttttg
    15601 agttgtagca ttcttgatcc tgatcttata agcagagtcc tgtttgccgg gctgttgaga
    15661 tgaataaggg catttctata gtgattatat agtgttgcag atgtgtgtat ggtttaaggt
    15721 ctaaataccc ttcaagctta gttcttgggt agtcagttcg gattggctgg ctgattttta
    15781 agcctttaat ggcttagtgg taagacaaac cagattacat ttgctaaaaa gtccctaagg
    15841 ctacaatcat tttttgtgac taatataaaa actagacctt ttgggatttg ta
//
LOCUS       DARYYD010000044        15670 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.045, whole genome shotgun sequence.
ACCESSION   DARYYD010000044 DARYYD010000000
VERSION     DARYYD010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15670)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15670)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15670
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.045"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(461..2872)
                     /locus_tag="TV188_001452"
     CDS             complement(461..2872)
                     /locus_tag="TV188_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEL1534794.1"
                     /translation="MKKKHIVLGSAVAILLATNAASYQFGMHKALNSSSKDNSIAYID
                     SKDGKKALPKEKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHFHFYNGKVPYDAIL
                     SEELLMTDPNYQFKQSDVVNEILDGYIIKVDGKYYVYLKPGSKRKNIRTKQQIAEQVE
                     KGTKEAKEKGLAKVAHLSKAEVAAVNEARSQGRYTTDDGYIFSPTDVIGDMGDAFLVP
                     HGSHFHYIPKKDLSPSELVAAQAYWNNKQGGKPSVIGGQPLPGQGDQPRPYDIPVNPI
                     HHPAGNLPSVGDPSLSFADKTFGELLDQLHGLDKKYRHVEEDGLIFEPTQVTLANAFG
                     YVIPHGDHYHIIPREQLSALEITLADRYLAGQTQGSPIAKPKPATQDQTAKEVTHQFL
                     GHQIKAYGKGLDGKPYDTSDHYVFSKASISSVDKAGITAKHEEHFHYMGFGELEQEEL
                     DQVAQWLQEHGQADEIARALVQSDGKDMSFDAKHVSRKVTNGGKVGYMMTKDGKEYFY
                     DREHLDLTQIAFAEQELMLKDKQHYIYDIVDTGVQPKLAVEVSSLPMHAGNATYDTWT
                     SFVIPHIDHIHVVPYSWLTKDQIATIKYVMQHPNTRPDVWSNPNHDEAGGVIANVTPA
                     DQRTSMENWQIIHSAEEVQAAIKAGRYAAPDGYIFDPKDVLAEGTFVWRNDSFSIPRV
                     GGRSLRTITKDELSHDEWQKVQELLGNKTSDAAESTIKPTKDQEPSAQDTAADGIEQT
                     KSLFDDIPNYGLDRATLERQINQLAEIAGIKPEYLIFVPEGVKFYDQKGHLMLYDVTT
                     LQQIK"
     gene            complement(2887..3810)
                     /locus_tag="TV188_001453"
     CDS             complement(2887..3810)
                     /locus_tag="TV188_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HEL1534795.1"
                     /translation="MKRKWIHLTLLLALFSGLVACSKPKEQSKQSRGMTIVTSFYPIY
                     AMTKAVSGELNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWADDLDPN
                     LKKSKVAVFEASKSLTLDRVTGLEDIEVTDGIDPATLYDPHTWTDPILAGEEALAIAK
                     ELSRLDPKHEAIYTENAQAFQKEAKELADEYTKKFKKTSSKTFVTQHTAFSYLAKRFG
                     LKQLGISGISPEQEPTPRQLTEIQDFVKEYKVKTIFAEDNVNPKIAKAIAKTAGAKVK
                     LLSPLEAAPKNNKSYLDNLRANLEALYQSLK"
     gene            complement(4137..5684)
                     /locus_tag="TV188_001454"
     CDS             complement(4137..5684)
                     /locus_tag="TV188_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1534796.1"
                     /translation="MKKQSLKKVSLLTVTVISSLALAANANTYTTYARDNVVTATSQA
                     AEGFDFVATILDSNGRALEGKTVVLLDTTANPAKQVASAVSNSNGQAIFTQLPLNINL
                     SVSVDGETKGYTVRTSLAGSKEAASFVAKGAGTKEPLYSKNVIDITVRNQDSEPLEGQ
                     TVTLKIRQGQLVGSLVSDKNGKVTFKDRLLDGTFYHYELNGKYIGQVMTKMSVNAYLD
                     TSSSSSSGTSPQSKDTPKQEDGKSSPLEEGFHFVVTALDKEDRVVAGKEVSLTALIDG
                     AKTTIASAKTNADGQAVFTKLPLSRNISVSIDGKLQGYTVRTSESNEHKAAAFYVDGK
                     GTKPVVYSKTPAIVTVYDANGNKLAGQEVVLKNRYGAIRAIGKTDQSGKATFVNQLMD
                     GMFYEIVINGVKIPKKASTGSDVSGFLTKAQIRTDNKLSESERHSKDTKPLGKEPKDP
                     EKDKNVAKPETKSSSNRNVAPKEGKKETKALPRSGESAAPMVAFMGVLLIGLAAVIGL
                     VTKRRSS"
     gene            complement(6309..7190)
                     /locus_tag="TV188_001455"
     CDS             complement(6309..7190)
                     /locus_tag="TV188_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEL1534797.1"
                     /translation="MKKALLIVNPSSGGEKAKEYEALAYDKLASYFDDVDVKHTEKGG
                     DAKRFAHEAAQQRLDSVFVMGGDGTVNEGISGLAEQDYRPKFGFFPLGTVNDLARALG
                     MSLDPEEAINQISFETTSPLDIGKVNDAYFMNVVAIGTLPEAINDVAPEEKTTFGKMA
                     YFMSGFKQLIKNKSYTFQLDIDGKTKEINSTTLLIGLTNSIGGFERILPEARVDDGLL
                     HLIYLKDSNLLETVKALPSLLKGVEASDQTLGYQTFKEATIAMKEGQLSINVDGDEGE
                     ALPITVKVLPQHLQVYR"
     gene            complement(7355..8356)
                     /locus_tag="TV188_001456"
     CDS             complement(7355..8356)
                     /locus_tag="TV188_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1534798.1"
                     /translation="MVTLKDIAALAKVSPATVSRVLNKDQSLSVGQETKHRILTIADE
                     LGYQKHLKATNSPKSKLKIAIVQWYSQEEELNDLYYYAIRIGIEKRAYELDYDIVRYF
                     NNDILRVSDDHAGIIAIGKFSACQIKELEALSQHLVFVDSDTLELGHPCVTTDFDNAV
                     LKVLDYFMSKGIYSIGMIAGEEKTTDGREALVDQRFRTYKNYASEHGIYQPRYVYIGP
                     FSAQSGYELMTQAIEELGDDLPKAFFIANDTLAIGALRALQERGLAVPERVELISFND
                     TPLTRQVFPALSSVTVFTEDMGRMAVDVLNRNILNPERVKTMTILATELTLRDSTIG"
     gene            8497..9669
                     /locus_tag="TV188_001457"
     CDS             8497..9669
                     /locus_tag="TV188_001457"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEL1534799.1"
                     /translation="MDIAQLKQSFTDVFGKEPDAVFFSPGRINLIGEHTDYNGGHVFP
                     AAISLGTYGLARKREDQQLRFFSANFEEAGIIEVDLNQLTFDQADLWANYPKGVLSFL
                     QKAGHLIDTGFELYVFGNIPNGSGLSSSASLELLTGIVAQELFGLDVERLDLIKIGQQ
                     AENHFIGVNSGIMDQFAIGMGADKQALYLDTNTLAYEAVPLDLGDHVIVIMNTNKRRE
                     LADSKYNERRAECEQALEELNALLDIKALGELDAQRFDEYSYLIKDGKRLKRARHAVL
                     ENQRTLQARQALEAGALEQFGRLMNASHVSLEHDYEVTGPELDTLVHTAWEQEGVLGA
                     RMTGAGFGGCGIAIVAKDKVDSFIETVGKAYTKVIGYAPAFYLAEIAQGARLLSRK"
     gene            9673..11157
                     /gene="galT"
                     /locus_tag="TV188_001458"
     CDS             9673..11157
                     /gene="galT"
                     /locus_tag="TV188_001458"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEL1534800.1"
                     /translation="MASLIDTFVRKVIEHSDYTSEDAIYIRNRVLALVGENHVWQETS
                     LTALIALKEALVELAAENGKIGRLPEEKDCLGAELMNMITPIPSVVNRRFWDTYAQSP
                     QQAISDFYQLSQLNDYIKTAAIAKNISFTVPSQYGDMAITINLSKPEKDPKAIAAAKK
                     AKASSYPKCQLCMENEGYQGRINHPARANHRIIRMSLGNEAWGFQYSPYAYFNEHSII
                     FNTEHVPMTISTSTFRQLLDIVDILPDYFVGSNADLPIVGGSILTHNHYQAGRHVFPM
                     EIAKQDKRFTFKGFPDIQAATLNWPMSVIRLRSSNKDQLVQLADTIRLAWRHYSDDSV
                     DIVAYTNQEPHHTITPIARKKEGQFELDLVLRDNHTSEQFPDGVYHPHADVQHIKKEN
                     IGLIEVMGLAILPPRLKEELVEVKKYILNQANQIADYHKDWADQITLRPDLSAITVDD
                     IIQEEVGSVFVRVLEDAGVYKRDQEGQAAFMRFLKSIGIEAIEE"
     gene            11167..12177
                     /gene="galE"
                     /locus_tag="TV188_001459"
     CDS             11167..12177
                     /gene="galE"
                     /locus_tag="TV188_001459"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEL1534801.1"
                     /translation="MTVLVLGGAGYIGSHTVDWLISQREEKVIVVDSLVTGHRKAVHP
                     EALFYKGDLADKAFMRQVFRDNPDIDTVIHFAASSLVAESMADPLKYFDNNTAGMIKL
                     LEVMREAKVKRIVFSSTAAVYGIPKTVPILESAPKCPINPYGQSKLMMETIMTWADKA
                     YGITFVALRYFNVAGAKPDGSIGEDHEPETHLLPIILQTAQGVREQVMIFGDDYDTPD
                     GTNVRDYVHPIDLADAHILAMAYLRQGKPSQVFNLGSQTGFSNRQLLEAARRVTGQAI
                     PAKKAARRPGDPDTLIASSEKARKVLNWKPSYDDIDKIIASAWAWHTKHPKGYDDKAS
                     GS"
     gene            12254..13297
                     /locus_tag="TV188_001460"
     CDS             12254..13297
                     /locus_tag="TV188_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEL1534802.1"
                     /translation="MNIYQDIIEYIDQVPVTQLRLINTNGVEAHLLTLGATLQAFLVS
                     NEKQPKNIILGHDRPSDYLKNPLCAGQTIGRVAGRIKRGSFQLEQQRVCVDTNENGHC
                     LHGGFKGFHKLHWPYDTRQTVDYLEVTFKRDILEADDHFPGDLTVSITYRLDNHNRLS
                     IHFKAHSMRGTSLFNPTNHVYFNLGQTQDLTNHNLYIAASHRIETDNELIPTGQKLAV
                     DQTVYDFRSIKSLYPAIVENNGFDTAFEIDQQAIGTTKPIAVLQDSVSHDQISIYSDR
                     NALVIYTMDSIQDGLYFGRDQGKEGLAREGIAMEAQTLPDAIHHNQFGDIILKEGGTK
                     SYTICLAYEHLPD"
     gene            13598..13741
                     /locus_tag="TV188_001461"
     CDS             13598..13741
                     /locus_tag="TV188_001461"
                     /inference="COORDINATES: protein motif:HMM:NF013921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1534803.1"
                     /translation="MIFDKDTNLKHKHRHQKFWYMGYYGDTAGKNLKTIAKYISNHYR
                     KIG"
     gene            14355..14516
                     /locus_tag="TV188_001462"
     CDS             14355..14516
                     /locus_tag="TV188_001462"
                     /inference="COORDINATES: protein motif:HMM:NF013753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1534804.1"
                     /translation="MPYSNAKLEPTNKTIKDMKEQAFGFRNFKNFKVKIPNALNITKE
                     ETKFISSRA"
     gene            complement(15108..15446)
                     /locus_tag="TV188_001463"
     CDS             complement(15108..15446)
                     /locus_tag="TV188_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1534805.1"
                     /translation="MAYDIYISNKAEQDLDEIYNYYLTEFSHSSAQKVIESLQSAISI
                     LEISPEGYVDFDDRVGRKLFPEGQLRMIPSKHFIVFYLIRQSRVDILRIRSTKTDYLN
                     DLENLFNNIL"
     gene            complement(15436..15669)
                     /locus_tag="TV188_001464"
     CDS             complement(15436..15669)
                     /locus_tag="TV188_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEL1534806.1"
                     /translation="MEEAKRILEAKNISVPDALNLFVERVVEEKDLPIKTAEQIRAES
                     FLNELISELDEGYQDILAGRTKPANEVFSKYGL"
BASE COUNT         4539 a         3507 c         3097 g         4527 t
ORIGIN      
        1 tagttttgga catttagttt cttctttctt gcgaatgggt acaattgtac ggctgctaac
       61 ctttttccta acccttttag acaccaaaaa actcccctta tcgtttttag tgattgtttt
      121 tcactgtcca ctttaaaggg gaggtctagc tattaaaggc taggcggttt tgactggagg
      181 actattaggt gtgaggttaa ttggtaaaaa ctctttctgt gctgccctcc ttaggtcata
      241 tagactttct tggaaccaaa acccacatat agcctacaga gatccaatgc tttaaaagct
      301 atgaggtgct aagctgctga tcaagtcagc ttctctgact gttgctgcaa gcaaaagcct
      361 actaagcgat cttaggctgt gaggcgtaag aacaggtcat cataccaata gctttttggg
      421 gataagctgt gatttgtatg ccttagctat tttatagtgt ttatttgatt tgttgcaatg
      481 ttgtcacatc ataaagcatt aggtgtcctt tttggtcata gaatttgaca ccctctggca
      541 cgaaaataag atactccggt ttaatgcctg ctatttcagc taactgattg atctgacgtt
      601 caagagttgc ccgatctaaa ccataattag gaatatcgtc aaataaagac ttggtctgct
      661 ctatgccatc tgcggcagta tcttgcgctg acggttcctg gtctttggtt ggcttaatag
      721 tgctttcagc tgcgtctgag gtcttattgc ctaataattc ttgaaccttt tgccattcat
      781 catgagataa ctcatcttta gtaatggttc ttaaagagcg tccaccaact ctaggaatgc
      841 taaaggaatc attacgccaa acaaaggttc cttcagcaag aacgtcctta ggatcaaaaa
      901 tatagccatc tggagctgcg taccgacctg ccttgatagc tgcttggacc tcttcggcag
      961 agtgaataat ttgccagttt tccattgaag tacgttgatc agctggtgtg acattagcaa
     1021 tgactcctcc agcttcatca tgatttgggt tagaccaaac atcaggacga gtattagggt
     1081 gctgcatgac atatttgatg gtcgcaatct gatccttagt tagccatgaa taaggtacaa
     1141 catggatatg atcgatgtga ggaatgacaa aagatgtcca tgtatcatag gttgcattac
     1201 cagcatgcat cggtaggctg gatacctcta cagctagctt tggctgaacg cctgtatcaa
     1261 caatgtcata aatatagtgt tgcttatcct taagcatgag ctcttgctct gcaaaggcaa
     1321 tttgtgttag gtctaaatgc tcacgatcat agaaatactc tttgccatct tttgtcatca
     1381 tgtaaccaac cttaccgcca ttggttacct tgcgactgac atgcttagcg tcaaaggaca
     1441 tgtctttacc gtctgattga actaatgccc ttgcaatctc atctgcttga ccatgctcct
     1501 gcagccattg tgcaacctgg tcaagctcct cttgctctag ctcaccaaag cccatgtaat
     1561 ggaaatgctc ctcatgctta gctgtgatgc ctgccttatc aacagaggaa atagatgcct
     1621 tactaaagac ataatgatca ctcgtgtcat aaggcttgcc atctaagcct ttaccataag
     1681 ccttaatctg atggccaagg aattgatgtg taacctcttt tgcagtctgg tcttgagtag
     1741 ctggctttgg cttagctatt ggactgccct gcgtttgacc tgctaggtaa cgatcagcca
     1801 aggttatttc aagggctgac aattgctcac gaggaataat atggtagtga tctccatgag
     1861 gaataacata gccaaaggca ttggcaaggg tcacctgagt tggctcaaaa atgagaccat
     1921 cttcctcgac gtgcctgtat ttcttatcca agccatgcaa ttgatccaac aattctccaa
     1981 aggttttatc tgcaaatgat aggcttggat ctcctactga cggcaaattc ccagctgggt
     2041 ggtgaatcgg gttaacagga atatcatatg gtctaggctg atctccttga cctggtaaag
     2101 gctgaccgcc aataacactt ggttttccgc cttgcttgtt attccaatag gcctgcgctg
     2161 ctactagctc acttggggat aagtcctttt taggaatata gtggaagtga ctgccatggg
     2221 gcactaaaaa ggcatctccc atgtctccaa taacatctgt cgggctaaag atatagccat
     2281 catcagttgt atagcgtcct tgacttcttg cttcgttaac agctgccacc tctgccttac
     2341 tcaagtgggc aaccttagcc aagccttttt ccttagcttc ctttgttccc ttttcaacct
     2401 gctcagcaat ttgctgcttg gtacgaatat ttttacgctt gcttcctggc tttagataaa
     2461 cataatactt gccatcaacc ttgataatat agccatctag aatctcgtta acaacatcag
     2521 actgtttaaa ctgataattg gggtccgtca ttaatagctc ttcactaaga atagcatcat
     2581 agggaacctt accattgtag aaatggaaat gatcaccatg tgaggttaca tagccttgat
     2641 ctgtgatttt aacaacgatt tgctctgcag agatcccctc ttctgcgctg atttgatcca
     2701 ttgttttttc tttggggagg gcttttttgc catcctttga atcaatatag gcaatgctat
     2761 tatctttaga tgaggaattt agagccttat gcattccaaa ctgatatgaa gcagcattag
     2821 tagccaataa aatggccaca gctgatccta aaacaatatg cttctttttc acgttttcat
     2881 ctccctttat tttaagcttt ggtaaagagc ttccaaatta gctctcaaat tgtctagata
     2941 ggacttgttg tttttgggcg ctgcctctag tggactgagc agcttgacct ttgctcctgc
     3001 tgttttagct atcgccttag caattttagg attaacatta tcctctgcaa aaatcgtttt
     3061 taccttatat tctttaacaa agtcttgaat ttcagttagt tggcgaggag taggctcttg
     3121 ctctggcgaa ataccagaaa tacctaactg ctttaagcca aagcgttttg ctagataaga
     3181 aaaggctgtg tgctgtgtga caaaggtttt agatgatgtc tttttaaact ttttagtgta
     3241 ctcatcagcc agctcttttg cttccttttg gaatgcttga gcattctcag tgtaaatggc
     3301 ctcatgctta ggatctaaac gactgagctc cttagcaata gcgagtgctt cttcacctgc
     3361 taaaatagga tctgtccagg tatgaggatc atacagggta gcagggtcaa tgccatctgt
     3421 cacctcaata tcctccaaac cagtaacacg atctaaggtt aaagatttgg aagcttcaaa
     3481 aacagcaacc tttgatttct tcaaattagg atccaaatca tcagcccagg cctctagggt
     3541 gtgagagtga taaacaaata aatcagcatc gtaaatggca gcaacgtcat ttacagatgg
     3601 ctcaaaggaa tgaatacctg cccctgactg aatcatccga acatcgttta gctcaccaga
     3661 taccgccttt gtcatggcgt aaataggata aaagctagtg acgatcgtca tgcctcttga
     3721 ctgcttgctt tgctccttgg gcttgctaca ggcaacaaga cctgaaaaaa gagcaagcaa
     3781 cagtgttaaa tgtatccatt ttcttttcat ataatctcct ttgctcatta accagttatg
     3841 aaccggttaa ttttaacagc tttagatgta tttgtcaaat tttttaataa aaaataaaag
     3901 ccattaaaac gatggcttaa tcagccccta acctgcttaa cctttataag aagccatagc
     3961 tctatgataa actgtggtct gtgacgcatg acctcactgt ctgttatctt actgttgcat
     4021 gatacgttta aaaaagattt agccttcttt ttttagattg tagaacggcg ctgaacaatc
     4081 acttaaccgt caaaaaaacg ccttgatagc tgcaagacgt ttttacttat ttggttttag
     4141 ctagagcgac gttttgtcac aagaccgatg acagctgcaa ggcctattaa tagaactccc
     4201 atgaacgcta ccatcggcgc tgctgattca ccagatcttg gcaaagcctt agtctctttt
     4261 ttaccttctt taggggctac attacggttt gacgaggact tggtttctgg cttagcgaca
     4321 ttcttatcct tttcaggatc ctttggctcc ttgcctaagg gctttgtgtc tttagaatgg
     4381 cgctcagact cgctgagttt attatcggtt ctgatttgag ctttggttaa aaagccgctg
     4441 acatcactac cggtagaggc ttttttaggt atcttgaccc cgttgataac aatctcataa
     4501 aacataccgt ccatgagctg attcacaaag gttgccttac ctgattgatc agttttgcct
     4561 attgccctga tagctccgta tcgatttttc agcacaacct cttgccctgc caacttattt
     4621 ccattggcat cataaacagt tactatggct ggtgtcttag agtaaacaac aggctttgtt
     4681 cctttaccgt cgacataaaa agcagcagcc ttatgctcat tagactcact cgtgcgaaca
     4741 gtatagccct gtagcttacc atcaattgag acactgatat tacgtgatag tggtagtttg
     4801 gtaaagactg cttgaccatc agcatttgtc tttgctgaag caattgtcgt cttagcaccg
     4861 tctatcagag cagtcaagct tacctccttg cctgcaacaa ccctatcctc tttatctagg
     4921 gcagtgacaa caaaatgaaa gccttcctct agcggacttg actttccatc ctcctgctta
     4981 ggagtgtcct tggactgagg tgacgtacct gatgacgagc ttgatgaggt atcaaggtaa
     5041 gcattaacag acatttttgt catgacctgc cctatatact taccattaag ctcataatga
     5101 taaaaggttc cgtccaacaa acgatccttg aaggttacct ttccattttt atctgagaca
     5161 agacttccca ccagttgacc ctgacgtatt tttagggtga ctgtttgccc ttctaagggc
     5221 tcactatctt gatttcggac cgtaatatca atgacatttt tactataaag aggctccttt
     5281 gtccctgctc ccttagcgac aaagcttgct gcctctttag atccagcaag actggttctc
     5341 actgtatagc ccttggtttc cccgtcaaca gaaacactca aattaatgtt taagggtaat
     5401 tgagtaaaaa tagcctgacc attgctgtta gagacagcag aagctacctg cttagcggga
     5461 ttagctgtcg tgtctaacaa gacaactgtt tttccttcaa gagcacgacc gttgctatca
     5521 agtatcgtgg caacaaaatc aaaaccctca gccgcttgcg acgtcgcagt gacaacgttg
     5581 tctctggcat aagtcgtata ggtattggca ttggctgcca aggccaagct agatataaca
     5641 gtaaccgtta aaagactgac ttttttcaat gactgtttct tcataaaaaa gctcctttat
     5701 tttgattaac tagcctagtt ttaatgggaa atatcccctt gatacccttt ctgaggtgat
     5761 aggaacagca gcaatctctc ttagcctatg atgcctaagc tttaaagcta agttttcaaa
     5821 gtccacctaa ggggctacat gccacaacaa aaagcatcag atgaacagac atctagaggc
     5881 aacagccgat ctaagataat agttagtagc cattttagct actctcaagg ctgtcgccgc
     5941 agtgatgatg tgattgtcta tgctttttaa taaaacttaa ctagttaaga tttttgtgct
     6001 gctatcctat caaataaccc ccgccaagtc aacaacaatg ctcataccac agcaagcaaa
     6061 gcattttgat gatgactgaa cagccaaatc agccaagccc caggcagcaa aaaagaggat
     6121 tcaaaccaaa tcctctctct actaagcctg ctgctgttaa cgtatcatgc taaaggcaaa
     6181 tggtatagcc acgctgatat gaaggtctga ttaacagcta cgacggacac gcttgttaag
     6241 gctaccattg ctaatcacac taggtcatat cctccaccgt ataagaatga ctaacttcat
     6301 tattcagatt aacgatatac ctgcaggtgc tgaggaagta ccttgacagt gattggtaag
     6361 gcctcaccct catcaccgtc cacattgata gatagctgtc cttccttcat ggcaatagtg
     6421 gcctccttga aggtttgata gccaagtgtt tgatctgaag cctcaactcc cttcaatagg
     6481 ctaggaaggg ccttcaccgt ttctaataga ttgctatcct tcagatagat aaggtgcagc
     6541 aaaccatcgt ccacacgtgc ctctggcaaa atccgctcaa agcccccgat tgaattggtc
     6601 aagccaatca agagtgttgt gctgttgatt tcttttgttt tgccatcaat atctagctgg
     6661 aaggtatagc ttttattttt gatcagctgc ttaaagcctg acataaaata agccattttc
     6721 ccaaaggtcg tcttctcctc aggggcaaca tcattgatcg cctctgggag cgtccctatg
     6781 gcaacaacat tcataaagta agcatcgttg accttaccaa tatccagagg actggttgtc
     6841 tcaaagctta tctgattaat cgcttcctct gggtctaacg acatgcccaa ggcacgtgcc
     6901 aaatcattga ctgttcctag aggaaaaaag ccaaacttag ggcgatagtc ctgctctgca
     6961 agcccgctga tcccttcatt gactgttcca tcacctccca tgacaaagac actgtccagc
     7021 cgctgctggg ctgcctcatg agcaaaccgt ttggcatctc ctcctttttc agtgtgctta
     7081 acgtcaacat catcaaaata cgaagctagt ttatcatagg ctaaggcttc atattccttg
     7141 gctttctcac cacctgagct agggttaaca atcaataggg cttttttcat ttatgatatc
     7201 ctacattttc tattatattt cacgactatt ataatcatta ttcaaaacat cgtcaaataa
     7261 tactcactat gtcattagtc agtcttaaag cttctaatat ggttgccgtc tagtgtttca
     7321 ttttactgaa ctctttaccc agctagctca atgcctaacc aatcgtgctg tctcttaagg
     7381 tcaactctgt cgccaatatc gtcatggtct tgacacgttc tgggttaagg atattcctat
     7441 taagcacatc aacagccata cgtcccatat cctctgtaaa tacagtcaca ctagaaagcg
     7501 caggaaagac ctgtcttgtt aaaggagtat cgttaaagga gataagctca acacgctcag
     7561 gcaccgcaag ccctctttct tggagagctc ttagagcacc tattgcaagg gtatcattag
     7621 caataaaaaa tgctttaggc aaatcatcac ctagctcctc aattgcctgt gtcataagct
     7681 catagccaga ttgtgctgaa aaaggaccga tatagacata cctcggctga taaatcccat
     7741 gctcagaggc ataattttta taggtgcgaa agcgctggtc cactaaagct tctctaccgt
     7801 cagttgtctt ttcctcacca gcaatcatgc caatgctata aatccctttg ctcataaaat
     7861 aatcaagaac tttcagcact gcattgtcaa agtcagttgt gacacagggg tggcccaatt
     7921 caagcgtgtc actatcaaca aacaccaaat gctgggataa ggcttcaagc tccttgattt
     7981 gacaagcgct aaactttcca atagcaataa tcccggcatg gtcatctgaa accctcaaaa
     8041 tgtcattgtt gaaataacga acaatatcat aatccaattc ataagctctt ttttcaatgc
     8101 caatgcggat cgcataatag tagaggtcat tgagctcctc ttcttgagaa taccattgaa
     8161 caatagctat ttttagcttt gatttagggc tattcgtcgc ttttaaatgc ttttggtagc
     8221 ccagctcatc agcaattgtg agaatgcggt gctttgtctc ttgaccaaca gacaagcttt
     8281 ggtccttatt taaaactcta gaaacagttg caggagaaac ctttgccaga gctgcaatat
     8341 ccttaagcgt taccatatca aaccttcttt ctgatttctt ctagtatatc acaagcattt
     8401 tcaaaagcaa tatttagtaa aattttagta aaaatgttga cgagcagctt agcgaagcgt
     8461 aaaatcaagc tatcaacatc gttaaaggag ccgctaatgg atatcgcgca acttaagcaa
     8521 agctttactg acgtttttgg caaggagcca gatgctgtct ttttctcacc gggtcgcatc
     8581 aacctcattg gtgagcacac tgattacaat ggtggacatg tctttccagc tgctatcagt
     8641 ctgggaacct atgggctggc ccgcaagcgt gaggatcagc agctgcgctt tttctcagca
     8701 aattttgaag aggctgggat tattgaggtt gacttaaatc agctgacctt tgatcaggct
     8761 gacctttggg ctaattaccc taagggagtt ctctcctttt tgcaaaaagc tgggcacctt
     8821 attgatacgg gctttgagct ttacgttttt ggcaacattc caaatgggtc tggtctgtcc
     8881 tcctcggcat cactggagct tttgacaggt attgtggcac aagagctgtt tgggcttgat
     8941 gtggaacggt tagatctgat taaaatcggt cagcaagctg aaaatcactt tatcggggtg
     9001 aattcaggta tcatggacca atttgccata ggcatgggag ctgataagca ggctctatac
     9061 cttgatacca acaccttagc ctatgaggct gttccgcttg accttggtga tcacgtgatt
     9121 gtcatcatga ataccaacaa gcgccgagag ctagccgatt caaagtataa tgaacgccga
     9181 gcagagtgtg aacaagccct tgaggaatta aatgcccttc tggatattaa agcactgggg
     9241 gaattagacg ctcagcgctt tgatgagtac agctacctta tcaaagatgg taaacgtctc
     9301 aaacgcgctc gccacgctgt tttggaaaat caacgaacac tccaagcaag acaggccctt
     9361 gaagcaggag cattggagca atttggtcgt ctgatgaatg cttctcatgt atccttggag
     9421 catgattatg aggtcacagg ccctgagctg gacacactgg tccacaccgc ttgggagcaa
     9481 gaaggggtcc taggggctcg catgacagga gcaggctttg gaggctgtgg cattgctatc
     9541 gtggctaagg ataaggtaga tagctttatc gaaacagttg gcaaggccta tactaaggtc
     9601 attggctatg ctccagcctt ttatctggct gagattgctc agggagcacg actactttca
     9661 aggaaataag atatggcaag cttaatagac acctttgtaa ggaaggtgat tgaacacagc
     9721 gactacacat cagaggacgc tatttatatc cgcaatcggg ttttagcatt ggttggtgag
     9781 aaccatgtct ggcaagaaac ctccttaaca gccttaatag ctctcaaaga agcattggtt
     9841 gagctagctg ctgaaaatgg caaaataggc aggcttcctg aagaaaagga ctgcttagga
     9901 gctgaattaa tgaacatgat aacccctatt ccaagtgtgg ttaatcgtcg cttctgggat
     9961 acctatgcac aatctcctca acaggctatc tcagattttt accagcttag tcagctaaat
    10021 gactacatca aaacagcagc aattgccaaa aacatctcct ttacagtgcc ttctcaatat
    10081 ggtgatatgg ctattaccat taacctatca aagcctgaaa aggaccctaa ggccattgca
    10141 gccgctaaga aggctaaggc atcctcttat ccaaaatgcc agctttgtat ggaaaacgaa
    10201 ggttatcaag gacggattaa ccacccagcc cgagctaatc atcgcattat ccgtatgagc
    10261 ttaggcaatg aggcttgggg attccagtat tcaccctacg cttattttaa tgagcacagt
    10321 attattttta atactgagca tgtgccaatg acaatcagta caagcacctt tagacagctc
    10381 cttgatattg ttgatatcct gccagactat tttgtcggct ctaatgctga tctgcctatt
    10441 gttggcggct ctattttgac ccacaaccat tatcaggccg gtcggcacgt ttttccgatg
    10501 gaaatcgcaa aacaagacaa acgctttacc tttaaaggat ttccagacat acaggctgcc
    10561 actctcaact ggcctatgtc agttatccga ctgcgcagca gcaacaaaga tcagctagtt
    10621 caattagcag acacgattcg actggcttgg cgtcattatt ctgacgacag tgttgatatc
    10681 gtcgcttata ccaaccaaga gcctcaccat accatcacac ctattgccag aaaaaaagaa
    10741 gggcagtttg aattagactt ggttctacgt gataaccata cctctgagca atttccagac
    10801 ggtgtttacc acccacatgc cgatgtgcaa cacattaaga aagaaaacat cggccttatt
    10861 gaggttatgg ggctagctat tttaccaccg cgcctcaaag aggaattggt tgaggtcaaa
    10921 aaatatatcc tcaatcaagc caatcaaatc gcagactacc acaaggactg ggctgatcag
    10981 atcacattac gaccagatct ctcagcgata actgttgatg acattatcca agaagaggtc
    11041 ggctctgtct ttgttcgtgt ccttgaggac gctggcgtct acaaacgtga tcaagaaggt
    11101 caagcagcct ttatgcgttt tcttaagagc attggcattg aagcaattga agaataggag
    11161 gaaaaaatga ctgttctagt tttaggcggt gcaggctaca ttggatcaca tacagtggac
    11221 tggctaatat cacagagaga agaaaaagtc attgttgttg atagcttggt gacagggcac
    11281 cgtaaagccg ttcacccaga ggctctgttt tacaaaggag acttagcaga caaagccttt
    11341 atgcgtcaag tctttaggga caatccagac atagacactg tgattcactt tgctgcctct
    11401 tccttggtcg cagaatcaat ggcagaccct ctgaaatact ttgacaataa cacagcaggt
    11461 atgattaagc tgcttgaggt catgagagaa gccaaggtta agcgcattgt cttttcatca
    11521 acagcagccg tctatggcat tccaaaaaca gtccccatct tagagtcagc gcctaaatgc
    11581 ccaatcaatc cttatggcca aagcaagctt atgatggaaa cgataatgac ctgggccgac
    11641 aaagcctatg gcatcacatt tgtggccctt cgctacttca atgttgccgg agcaaagcca
    11701 gatggctcca tcggtgaaga ccacgagcca gaaacacatt tattacccat tatcctacag
    11761 actgcacagg gagtgcgtga gcaggtgatg atttttggtg atgattatga cacaccagat
    11821 ggtactaacg ttcgagatta cgtccatcct atcgatttag ctgatgcaca cattttagcg
    11881 atggcatacc tgcgtcaggg caaaccatca caggtcttta atctagggtc tcaaacaggc
    11941 ttttccaatc gtcaactgct tgaagccgct cgtcgggtaa caggacaagc cataccagcc
    12001 aaaaaagctg caagacgtcc cggtgatcca gacaccttaa ttgcgtcatc agaaaaagca
    12061 cgcaaggttc tcaattggaa gccaagctat gacgatattg acaagataat cgcatcagcc
    12121 tgggcctggc ataccaagca tccaaaagga tatgacgata aagcaagtgg cagctagtcc
    12181 ctcaagacag ctaccacagc aagtagtcag cctcccttaa ttcatacacc tatactaata
    12241 ggagaaacaa actgtgaaca tttatcaaga catcattgaa tacatcgatc aagtgccagt
    12301 cacccagcta agactgatta atactaacgg tgttgaggct cacctattga cactaggagc
    12361 cactctacag gcctttctag tgtcaaatga aaagcagcca aaaaatatca ttttgggaca
    12421 tgaccgacca agtgactacc taaaaaatcc tctttgtgca gggcaaacca ttggccgagt
    12481 agcaggtcgc ataaagagag gaagctttca gctagagcag caaagggttt gtgttgacac
    12541 caatgaaaat gggcattgcc tgcatggagg cttcaagggc tttcataagc ttcattggcc
    12601 ttatgatacc cgccaaacag ttgattacct tgaagtaacc tttaaaaggg atattttaga
    12661 agcagatgac catttcccag gtgacctgac cgtaagcatt acctaccgtc tagacaacca
    12721 taatcgttta agcattcact ttaaggctca tagcatgaga ggcactagcc tattcaatcc
    12781 aaccaaccat gtttatttta atttagggca aacacaagac ttaaccaatc acaacctata
    12841 catcgcagca tcacatagga ttgaaacaga taatgagcta atcccaacag gtcaaaagct
    12901 agcagttgac cagacggtct atgattttag atcaataaag tccctctatc ctgctattgt
    12961 cgaaaataat ggctttgata ctgcctttga aattgatcag caggctattg gaacaaccaa
    13021 acctattgct gtcttacaag acagcgtcag ccatgaccaa atcagcatct actctgaccg
    13081 aaacgcactc gtcatttata ccatggacag tatccaagat ggcttgtatt ttggaagaga
    13141 tcagggcaag gagggactgg ctcgtgaggg gatcgctatg gaagcacaaa ccctgcctga
    13201 tgctattcac cacaaccagt ttggtgacat tatcctcaaa gaaggaggca ccaaaagcta
    13261 cactatctgc ctagcctatg agcatctgcc agattaacat aagtacagcc aagctttaat
    13321 gaaataacaa gaccttgatt tttttgaatt gcaccccaac cgttagccaa aaactctaac
    13381 aagcgaggat cagttcattc atcaaggtct tttcctcttt ttatctatag gcgttacaaa
    13441 gtagatatag gaacatcata ccaaatatgt ggaatgctaa gagcttatca tcacaaagcg
    13501 aatacatgtt ccgactacat ctatgcatta gtaagtcttt ttcctaaacg aagtgttgcc
    13561 agctttatga gatacttaaa agtataagag cagcctaatc atttttgaca aagacaccaa
    13621 ccttaagcat aaacataggc atcagaaatt ttggtatatg ggctattatg gagacacagc
    13681 tggtaaaaat ctaaaaacga tagccaaata tatttcaaat cactatagga agatagggta
    13741 gcaaaccaac tgacatcatt tgagaccatt gatccattta caggccaacc aaataagaaa
    13801 aagtaacctt ttgattgaac tcccgctcgg aaaagtggag cgcgagtatt caatgacctc
    13861 gttatcctcg accgatgaga gcagcttata gtcacagtat aaagaggctg gaacagacaa
    13921 cctcttttga ttgacaataa gtgtttgata gcattgtatg ggattacttt cacatcattc
    13981 agcacctggg tcgagctttg atgaccgcca gaattgatag ccattatgaa gggctttgag
    14041 cagccatttc tgctttatcg aaccataaaa tatcattgat gactgctcca aaaggacagt
    14101 cataaactgt ctgatcagcg cttctagtca cgaaccttta agcaaacctt aatactcaaa
    14161 aaaggtaagt cagaaaatac ttgatttctc agatgagctg tggaattacc acgaccttta
    14221 ccagctcttg ctctttcatt ttcaaaaagt gggtaaccga gtttttcggg ctgattgaag
    14281 agctttaagc ttggtcaatc atcacgtttt aaccgtcctc aaaatctttt tgaaatacaa
    14341 accctacatc acaaatgcct tattccaatg ctaaattgga gcccactaac aagactatta
    14401 aggacatgaa agagcaagcc tttggattta ggaactttaa gaacttcaaa gtcaagattc
    14461 ccaatgcttt aaacatcaca aaagaagaga caaaatttat ctcttctcgt gcttagctat
    14521 cagtcaccca ctgcagttga cattgagcca aattatagag ccattttcgt agaaagcaca
    14581 gaaaaaacac ccatgaggta aactcttgag tgctttgaaa cgttgatata atgcgatata
    14641 ttaacgtttt gaggcacgga gactgcgtct cctttgcagc cgtattcgta agcgactaaa
    14701 gccgcaacga ctacgtcaat tgcgtcgcca gttctttcaa aaaagaaaat accccatggt
    14761 aacccatgaa gtattgttct gctgtattgt agctggttct taacgttttg agaactgact
    14821 agctttacga gctttcttaa gacctggttt tgggtgacaa aaaccaaata tctgtaaaag
    14881 cttatcaaat caagctttca aaactcattt tcattaaata taagcacttt taacccaatc
    14941 ctacaaataa tagattacca ttagattacc aaaactcagt tttcggagct tatgtagttg
    15001 agaaaatctc gtatttactt tgcttttata tatccacttt atactatcat cccgtcataa
    15061 cagagcatga ttaaatagtt acataaaaaa caatacttac tctatcatta aaggatattg
    15121 ttaaaaagat tctctaaatc atttaaataa tcagttttag tacttctaat acgaagaata
    15181 tctacccttg actgacgaat taaataaaat actatgaaat gcttactagg aatcatcctt
    15241 agctggcctt caggaaatag tttacgtcct acacgatcgt caaaatcaac ataaccttca
    15301 ggggatatct caagaataga aatagctgac tgcaaagatt caataacttt ttgagcgctt
    15361 gagtgcgaaa attctgttaa atagtagtta tagatttcat ctaaatcttg ttctgcctta
    15421 tttgaaatat agatatcata agccatattt tgaaaatacc tcattagctg gcttcgtacg
    15481 tcctgctaaa atatcttgat acccttcatc aagctctgat atcagttcat ttaaaaatga
    15541 ttcagctcta atttgttctg cagttttaat aggtaaatct ttttcttcca ccacccgttc
    15601 aacaaataga ttaagagcat ctggaacact aatattttta gcttctaaaa tacgctttgc
    15661 ttcttccatc
//
LOCUS       DARYYD010000045        14647 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.046, whole genome shotgun sequence.
ACCESSION   DARYYD010000045 DARYYD010000000
VERSION     DARYYD010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14647
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.046"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..255
                     /locus_tag="TV188_001465"
     CDS             <1..255
                     /locus_tag="TV188_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HEL1534807.1"
                     /translation="QFTRAGIIENLIFKGFVERDKKNLIATHKGISLVAIVADNFKSA
                     ETTAKWEMELSDIAQGKSSKEEFLEAIENEIKEAVSTYSK"
     gene            339..518
                     /locus_tag="TV188_001466"
     CDS             339..518
                     /locus_tag="TV188_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HEL1534808.1"
                     /translation="MKDTFIDTAKVMSKGQVTIPKRIRELLNLENGDYVTFVVNKDRV
                     EIQNSNVFIEENIKK"
     gene            537..1964
                     /locus_tag="TV188_001467"
     CDS             537..1964
                     /locus_tag="TV188_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEL1534809.1"
                     /translation="MTIDEIKKLIQAGEKIDVEFKESKNALTKDVFDTVCSFNNRNGG
                     HILLGANDKREIVGVSEDKVDKVIKEFTTAINNPQKMYPPLYLLPETFEIEGKQVIYI
                     RVPEGYQVCRHNGRIWDRSYEGDINITDHSELVYKLYARKQGSYFVNKVYPNLDIDFL
                     DASVIDKAKKMAVFRNKNHVWENMSNEELLRSANLILTDPETKREGITLAAILLFGKD
                     NSIMSVLPQHKTDAIFRVENKDRYDDRDVVITNLIDSYDRLIEFGQKHLNDLFVLDGI
                     VNVNARDRILREIVSNTLAHRDYSSGFPAKMIIDDERITVENSNLAHGMGALDLQKFE
                     PFPKNPAISKVFREIGLADELGSGMRNTYKYTQLYSGQNPLFEEGDIFRTIIPLKKIA
                     TQKVGGDNVAHDVAQGVAHDVAHDKIALAEFIKEKVRSNDRITRKAIADEAGVSVKTI
                     ERAIKEIDNLKYVGSGNSGHWELNE"
     gene            2136..8966
                     /locus_tag="TV188_001468"
                     /pseudo
     CDS             2136..8966
                     /locus_tag="TV188_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365295.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
     gene            9476..11241
                     /locus_tag="TV188_001469"
                     /pseudo
     CDS             9476..11241
                     /locus_tag="TV188_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678622.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase"
     gene            11349..13259
                     /locus_tag="TV188_001470"
                     /pseudo
     CDS             11349..13259
                     /locus_tag="TV188_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989360.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            13303..13962
                     /locus_tag="TV188_001471"
     CDS             13303..13962
                     /locus_tag="TV188_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006627214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1534810.1"
                     /translation="MDYKTMRNQIEDMANDNHKDFVKAIISVEKGINDESALDKLYDA
                     YMDNDSLNLLHEEFDYMIEDLREQGQIKDLPYVQEEKDNLINIVGNIVGKVDVAEREN
                     KNGEAFKVANFSVVSKDDEGNKVYHNCSAYGEKSDIPKDFKQGDFVKLFGQIRTSIDD
                     NGKEHSNVRILSSKLLKAKEQMKGQEEKKESVLGAIKKYQSEDKEKPKEKRDASKEAE
                     R"
     gene            14112..14327
                     /locus_tag="TV188_001472"
     CDS             14112..14327
                     /locus_tag="TV188_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1534811.1"
                     /translation="MSKISYKKLFKKMIDLDMKNSELMEKAEVSRSTFYKMKNSENIT
                     TDVIVRICDSLNCGVNEIMELVDDENN"
     gene            14311..>14647
                     /locus_tag="TV188_001473"
     CDS             14311..>14647
                     /locus_tag="TV188_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HEL1534812.1"
                     /translation="MMKIIDYVIESTNKYIKQMPKEIRKKNGQFFTSKETALFMASLF
                     DLSSFSKEISILDPGAGSGILTAALIQRIIDTDKIEAIKITCYETNDDILELLNANLS
                     WISKNTSLKI"
BASE COUNT         5395 a         2109 c         3271 g         3872 t
ORIGIN      
        1 cagttcacaa gggcagggat tattgaaaac ttaatcttta agggatttgt agaaagagat
       61 aagaaaaacc ttatagccac acataaagga ataagccttg tagcgattgt agctgataac
      121 tttaagtcgg cagaaactac cgcaaaatgg gaaatggaat tatccgatat tgctcaaggg
      181 aaatcttcaa aggaagaatt tttagaagcg attgaaaatg agataaaaga agcggtttca
      241 acttatagta agtaagatga cactaatttc agagtagaaa aaatatctta aaagtgctat
      301 aatcttttgt aggaaaagta gggcgaaagg gattagtcat gaaagataca tttatagata
      361 ctgctaaagt tatgtcaaaa ggacaggtta ctattccaaa gaggattagg gaacttttga
      421 atttagaaaa tggagactat gttacttttg tagttaataa agatagagtt gaaattcaaa
      481 attccaatgt ttttatcgaa gaaaacatta agaaataaag gtggtgaaat aaacagatga
      541 cgatagatga aattaagaag ttaattcaag ccggagaaaa aatagatgtc gaatttaaag
      601 aatccaagaa cgctttaacc aaagatgtct ttgatacagt atgctctttc aacaatagaa
      661 atggcggaca tattttactt ggtgcaaatg ataaaagaga gatcgttggt gttagtgaag
      721 ataaagtaga taaagtgatt aaggaattta ctacggcaat caacaatccg caaaagatgt
      781 atccaccact ttatttgctg ccggaaactt ttgaaattga ggggaaacaa gttatttata
      841 taagagttcc tgaaggttat caggtatgca gacataacgg aagaatttgg gataggtctt
      901 atgaagggga catcaatatc acagatcatt cagagcttgt atataagcta tatgcaagaa
      961 aacaaggaag ctattttgtt aataaggtat atccgaatct tgatattgat tttcttgatg
     1021 cttctgtcat tgataaagct aagaaaatgg ctgttttccg aaataaaaat catgtttggg
     1081 aaaatatgag taatgaggag cttcttagaa gtgccaattt gatactgaca gatccggaaa
     1141 caaagcgtga aggaatcaca ttagctgcta ttttgttatt tggaaaagat aactctatta
     1201 tgtccgttct tccgcaacac aaaactgatg ctatattcag ggttgaaaat aaggatagat
     1261 atgatgatag agatgttgtc ataacaaatc tgattgacag ctatgacaga ctgatagaat
     1321 ttggacaaaa gcacttgaat gatttatttg tcttggacgg aattgtcaat gtcaatgcaa
     1381 gagacaggat actcagagaa atagtttcca atacgctggc tcatagagat tattcaagtg
     1441 gttttcctgc aaagatgatt attgacgatg agaggattac agttgaaaac agcaacttgg
     1501 ctcatgggat gggagcttta gatttacaga agtttgagcc atttcctaaa aatcctgcta
     1561 tatctaaagt ttttagagaa ataggtcttg cggatgaact tggttcagga atgcgaaata
     1621 cctacaaata cacacagctt tattcaggac aaaacccgct atttgaggag ggagatatat
     1681 tcagaacgat tattcctcta aagaagatag cgacacaaaa ggttggaggc gacaatgtcg
     1741 ctcacgatgt cgctcagggt gtcgctcacg atgtcgctca cgataagata gctctcgcag
     1801 agtttattaa agaaaaagtg agaagcaatg ataggattac aagaaaggct attgcagatg
     1861 aagctggagt tagcgtaaag actatcgaaa gagctataaa ggaaatagat aatctgaagt
     1921 atgtaggaag tggtaatagc ggacactggg aactgaatga ataaaattaa gttgcaaaac
     1981 aaagattttt ataaataaga gggtgctatg aataccataa aatgaggatt tgtagtagga
     2041 aatttaagtt gcagcaagtt gcaatacaca gaatcaaaag gtgattagag taaaatctaa
     2101 ccgccttttt tgtttggaaa aagaaggagg taaaaatgcg aataaatgat tttcataaca
     2161 ttttggagct tgtaaaacaa aatattttgc aaagtgaagc agaatacctg aagctcctaa
     2221 aggttgtcgg aaacaatcaa agatatgact ttagaagtca gttaagtatt tatgatagaa
     2281 attctgaagc gacagcctgt gccaagttcg actattggag ggaacgcttt aaccgtactg
     2341 ttatgagagg acaaaaaggt atccccattt tagaggacta cggcacatac aaaaaagtgg
     2401 catatatctt tgatataagt cagacggttt caagaaatag ggatgtcaat gaggtcaatc
     2461 tttggagatt tgataaagaa gctcataggg atgtcttaaa ggaaatgata aaaaacgagg
     2521 gctatgagga aagtgaaagc accttagaaa atatcttttc tttaagtaga ctctacggtg
     2581 atgaaaagat agacagcctt atgaatgagc ttagaatagc tgatgaggat agaatatctt
     2641 ttaccaagtt tgtgagggac tcagtgagtt atgcagtagc ttcaagattt aatgtagact
     2701 atcctatgga taatgagctt ctaaaggaaa actttgcaat gcttgatagc atttccctta
     2761 tgagtcttgg tgaaatcgta tcggatatta gtggaaagat tattgatgaa accattcaaa
     2821 aaagcaaaga gcttgagctt caaaaagaag ttttaagagg aaaagaagca ggatataata
     2881 ggattaaaga aaaaattgag aaaggagata atgatgtact tcgacgagat gatcaggaaa
     2941 gaaatgaaaa tgagcgagtt ctccgaaatg gagagtacgg acgagataat agagaaaatc
     3001 agggagaata cactaaacag cttggaggaa cagacggact tcataaggga gtatccgaat
     3061 ccgacctacg cagtaatgag gctggattac ctttcagaga gcgaggagca gagccacttc
     3121 gagatgttag tggatctata caaggagagg aagctaacag gacacctgat ggatattcag
     3181 aaacaggcga tagactttat gaggacagag aagccgaaat tgatggtagc ttggaagata
     3241 gaggacgaga acgatccgca gtatggggcg atgatttcag ctctgaagga aatgacaatc
     3301 aaggaagtat taaaaattta aaagataata ctgaggtaga gataagagaa gctgaaaagg
     3361 cttctttttc tttacccgaa aattcatatg gacagatgag acttaccatt ccattaactc
     3421 agagggatat agatactgtc cttattaacg gaggaaatca cgatggaagt agacttcctg
     3481 ttatcgctga gttttctaaa ggaaaaagta atgaagaatt aggagaatac ctaaaagata
     3541 tatttagagg cggtaatgga ttttacattg atgaaagaga agtatcttcc tggtattcgg
     3601 ataaaggcat tcatttagcc tacgggacat ctgcaagaga agatactacg caaattttaa
     3661 gctggagcga tgctgcaaag aggataaatg agcttcttga taatggtgag tttgctacaa
     3721 atgtagagat ttctgaggct cctgattatg aaagagataa gatttcagag tccttatggt
     3781 atctaatgca tgatttaagc gaagaaggac aaggatattt tgaactattg aaaacaagtg
     3841 gaagaggctt tccggaagaa acaaaaagat tgtctgaagc attaaaaaat cccgactacc
     3901 taaaggaaac gatcaaagaa tacagcaggt ttttagaagg atacaaagaa aacagaaatg
     3961 tattaaggtt tcactatcac aaggtagata gcctttgtca gaggttacag gaacttgagc
     4021 tgtcacgaaa ggaatatagt accaatctaa cagagcttcc gaaggtaaag tccttcatta
     4081 cagaagatga agtccttgaa agtctttcaa gaggaagagg cgtcgataga ggaaaagagc
     4141 gaattacaaa gtttttcaaa gaaaatcata ccttgcagga aaaagctaat ttcctaaaag
     4201 acgaatatgg cataggtggt agaagtcatg cagtatcggg ggcaatggga agtgatgaat
     4261 ggcatgatgc aaaggggctt aaattacaga agaataattg taatgatgtt tttcttactt
     4321 ggtcaagtgt ggcaaagcgt atagaggagc tgctttctaa aaatctgtat gaagaaaaga
     4381 aaatagaaag taagtcagag gtagaagaat caaaagagct acaatattat tctaaagata
     4441 atcctgaaaa cttaatgact gatgaaatgc ttgaaagagt gcctgagctt tacgcacagg
     4501 aagatgtagc tttagcggat aaagaggttc atgcagcata tattattcct ttccgttcta
     4561 actggacttg gtatatgacg gaatatgata gggaaagcgg tgatgccttt ggacttgtgt
     4621 taggatttga acctgaatgg ggatatttca atcttgaaga attgaaagaa ttaaatgctc
     4681 aaaggcttat tttagaggat tttccaaaga cttttagaga gcttaaagat acagaacttg
     4741 caaagcagat ggatgaacag gaacttcaat cagtctttaa cggagaactt agctttgaag
     4801 ataaagaaga acttgaaata tctgaagaag tggaagaaag agtagctgca acacctgttc
     4861 aggaaacact atttgattat ctgaaggaga aggaagaagt agagcttaac gaagaaaaga
     4921 aaagtatttc agatgaattt gcagttaaag agggcgatac cgtctatttt aatcatgaag
     4981 aatatactgt aagggaaatt gctgaaaata aaatcacaga aagatatgac ttatggcttg
     5041 atccgggaag aagtggaaac catcaaatcc ctattgtagc ctttacagat aatgaagatt
     5101 tattaagaca agtaagccct gaaagacctg cgtttatcgt tggagatgaa attaaataca
     5161 aggataaaga ctataccatc acacgctttg acgatatggg aaataatcta aagacggtaa
     5221 cggttaagga taataccgaa tatcttggcg gtatgataac aggctcagat gtaattcctt
     5281 atcgtcttga aagcgatctt gagagggtat ttgaaaatct gacatataaa aagcctgaaa
     5341 ctattgctaa agaaagtgaa ataaagaaag cagaagctca taacttcaag attacggaag
     5401 aaacattacc tgacaagtta tctccaagtg aaaggctaaa taataacctt gaagccatct
     5461 ctatgctgag tcgcatcgaa agtggacaaa gagagtttga cagtacagct caggaagttt
     5521 tagcaaggta tgtaggctgg ggtggacttg ctgatgtatt cgatgaagaa aaaggcggac
     5581 agtggaaaga agcgaggagc tttctaaagg aaaacttatc tcaggcagaa tatgaagctg
     5641 caagagaatc taccctaacg agcttttaca caccgaaaac tgttattgac ggcgtatata
     5701 agacactttc cgatatggga tttaagagcg gaaatatcct tgagccatca atgggcatcg
     5761 gaaactttat aggaaatctt cctgatgaaa tgaacaagtc aaagttttat ggtgtagagc
     5821 ttgacagtat aagcggtagg attggaaaac ttttataccc tgaaagtgat atacagatta
     5881 aaggacttga agaaacttct ttttccaata acttttttga tgttgcaatc ggcaatgttc
     5941 cctttggaga atacaaagta aatgacaggg aatacaatcg taataacttc cttattcatg
     6001 actatttctt tgccaagtcc attgataagg ttagaaacgg cggggttatc gcctttatta
     6061 catcaagtgg aacaatggat aaaaaggatg aaagtgtaag acgctatctt gcagcaagag
     6121 cagagttttt aggagctatc agacttccta atgacacctt taagggtact gccggcacag
     6181 aagtaacctc agatattatc ttcttaaaga aaagagatag cgtattagag cgtgatgaag
     6241 attggataca ccttgcggaa gatgaaaacg gtcttgtata taacaaatac tttgttgatc
     6301 atcctgaaca ggtacttggc tcaatgcgtg aagtaagcgg aagatttgga aaaactctaa
     6361 cttgtgaacc gatatcttat ttaggcacag agctaaatat ggcttcatta aaggatcgta
     6421 tcgagattgc aggagaaaga atttcaaaag atgccaagta tgaagaaata gagcttttag
     6481 atgatgaaat cacttcaatc cctgcaacgg atgatgttaa gaacttttcc tataccatta
     6541 ttgatgatga agtctattac agagaaaact cactgtttat caaaaaggaa gtaaccgata
     6601 aaaacaaaga aaaaatcaag gattatcttg agctgaatgc tgccttaaaa aatgtgattt
     6661 acaagcagaa agaaggtttt agtgaggaag aaatcaaggc ttcacaggaa aaactaaatg
     6721 aagtctatga ccgtttttct aataagcatg gctttgtaaa taatttaagc aatacaagag
     6781 ctttaaaaga ggatagcaac ttcccgcttg tttcctccat tgaaatcctt gatgaagaaa
     6841 actttaaggc aaagggagat attttctcca aaagaactat tacaaaggct aaagtcatag
     6901 atcatgtgga tacttcttta gaagcccttg tcttatcggt atctgaaaaa ggatatgtgg
     6961 actttgacta tatggaaggt cttacaggaa aagacagacc gactttgatt gaggagcttc
     7021 gaggggaaat ctacttaaat attagggaag aacaaaactt ttatagacct ctatccttta
     7081 accccgaaga tggagatttg ccttttgcct gtgccaatgg cagtaattcc tacaaatacg
     7141 gctatgtaac aaaggatgaa tatttaagtg ggaatatcag ggacaagatt gccatagtag
     7201 atagctatct atcaaagctc agacagacgg aaagagagtt acctcatctt ggctatgcag
     7261 aagatggtaa agaaaaagag ctgattagct atgagatgaa tcgtttggaa taccaaaagg
     7321 ctgagcttac aaaagttcta ccaaaggagc ttgaagcaag tgagataagt gttcgtcttg
     7381 gtgcgacttg gataccgatt aaagatattg aaaaatttat ttttgaaacg ctgaaaactc
     7441 cgggatatgc aagatgggat attaaggtta agttttcaaa cctgacaagt gagtggaata
     7501 tagaaggtaa aagtagggat agaggaaatg acctcgctga aatgacttac ggtacatcaa
     7561 gggtaaatgc ctataagctg attgaagatg ccttaaacct gaaagaaaca aaggtatttg
     7621 accagattgt aaatccggac ggctctaaaa cttctgtact aaataaaaaa gaaaccatgc
     7681 ttgcagggca aaagcaggaa ctactaaaag aagaatttaa gaactggata tttaatgatc
     7741 aggagagaag aaaccgtctt gtaaaactgt ataatgagcg ttttaactct atccgaaaca
     7801 gagaatatga cggaagtaat ctttcctttg agggaatgaa tactaaaata gatttaagac
     7861 ctcatcagag aaatgccata gcaagaagtc tttatggagg caacaccctg cttgctcatg
     7921 tggtgggcag tggaaagacc tttgaaatgg tggcttccgc aatggaaagt aaaagacttg
     7981 gaatgtgtag taagtccttg tttgttgtac ccaatcactt aacaggacaa atcggtcgtg
     8041 agtttatgca gctatatccg tcggcaaata tcatggtggc agataagaaa gattttgagc
     8101 cgaagaaccg taagcgtttt atcggtcgaa ttgccacagg agaatacgat gccgttgtta
     8161 tcgggcatac gcagtttgaa aaaattccta tgtctaagga atatcaggag aagcatatcc
     8221 aagatcagat tgatgaaatc gtaaactatg tagaagaata caagcatgac agaaatcaga
     8281 actttacagt aaaacagctt gaaaagacaa agaaaaaact ggaaacaagg cttgagaaat
     8341 taaatgacga ttttaagaaa gatgatgtca ttacctttga ggaattagga gttgataagc
     8401 tctttgttga tgaagcacac aactacaaaa atctctatct ttatacaaaa atgcgtaatg
     8461 ttgcaggaat cggtcaaagt gaagccttta agtcctccga tatgtttatg aagtgtcgct
     8521 atatggatga aatgacaaac ggaaaaggca ttgtctttgc aacgggaacg cctgtatcaa
     8581 actccatgac tgagctttac actatgcagc gttatcttca gtatgagagc ttaaagaaaa
     8641 ataatctgga gcattttgat agctgggctt ctacttttgg ggaaacgcag tctgcttttg
     8701 agctttctcc ggagggaaca ggatacagag taaagacaag attttccaag ttctataact
     8761 tgcctgaact aatgtctatg tttaaggaag tcgctgacat tcaaacagcg gatatgttaa
     8821 atcttccaac acctgaggca cattatgaag taattaagac cttgccaagt gaggagcaaa
     8881 aggaaattct aaagagcctt tctgaaagag cagatgatgt gagaaatagg gtggtagagc
     8941 ctgacaaaga taatatgcta aaaattgtgc gctgttaagc gtaaaaatgt atctccctca
     9001 cagagggata ttattgaaag taaataatag gaacaactaa ctaacctagc ggggaaaccc
     9061 aaaggggaca atagcatgtt agtaaagcgg ataaggagtg agttacaacg ctttgatgtg
     9121 ccgcaagttc cgtaacctat ggttaaggct aaactgcttg aacctcaatt ctgactaggt
     9181 gcaaagcatc gcccatcgga aagtaactga gaccgatgtt actgtatatt cgttgttgtg
     9241 attttggacg aataactttc tacagtaaaa gagcatacga taagtatgaa taaaggaatg
     9301 agtgaggaac ctaagggtta ctagaacgta catttttaac gaatagcagg attgcctaag
     9361 aggggggacc cttatggtaa cggagtcacc gtagtagtcc gagcaaggga aatccttgta
     9421 catggcgaag ggtgacaggt aatttcgatt agttagaaag gattaggtgc gtgggatgcg
     9481 tacagccaaa actattttaa cggtcattca tgaacgtgga aaacaagata aaccactcga
     9541 aagggtttat aagttactat ttaatcgtga actctatctg atagcctatg caaagttata
     9601 cccgaataat ggagcaatga caaagggtgt tacagaggaa acgattgatg gaatgtctat
     9661 tcaaaaaata gatatgatta ttgaacaatt aagacaagaa acctattact ggagaccagc
     9721 taggagagag tacattccta aaaagaatgg aaaacaccgt cctttgggaa taccagtatg
     9781 gagtgataaa cttcttcagg aagtgattcg catgatatta gaagcctatt atgagccaca
     9841 atttagtgaa cattctcatg gttttagacc aaaaagaggg tgtcatacag ctttacaaga
     9901 aattcagact tggaaaggga cacgttggtt catagaagga gatatctcta gttattttga
     9961 cacgattgac cacgatgtat taatcactat gttgtctaga caaattcagg atggtcggtt
    10021 tattaggctt atcaaaaata tgcttgaggc aggatatctt gatgattgga agtttcacaa
    10081 gactattagt ggaacaccgc aaggtggagt tattagtcct ttattagcta atatctattt
    10141 acatcaattt gataagtggg tcggtgaaga gctgatacct caatatacaa gaggtaaaaa
    10201 gcagaaagca aactcagcct ataatcgttt gagtagaaga attaaatgct atcaggataa
    10261 aggagattat aaaaaagctc atcagttaat tgttgagaga agaaatctcc cttcagttga
    10321 tacttatgat accagctatc ggagattaag atatgttcgg tatgcggatg actttattct
    10381 aggctttaca ggttcaaaag ctgaggcaaa ggctataaag aagcaaattg gagacttttt
    10441 aaatactaag ttatctttgg aactttctca agaaaagact ttgattaccc atgcgactgg
    10501 agaatcagct aaatttctgg gatatgagat aaaagcacaa cgtgtcaatg attatattga
    10561 taacaaaggg agacagagtg ccaatggtgt tatcgcatta tttgtacctg catcagttat
    10621 tgaaagcaaa tgccgccaat acatgaaaaa tggtaaagct attcatcgta ataacttatt
    10681 gcatgatgat gactttagta tcgttcaaac ttaccaacaa gaatatagag ggctagttca
    10741 atattatata ttggcacaaa atttgtcatg gttctcaaaa gtctattggt atatggaaac
    10801 atcactcctt aaaacattag catttaaaca tgagtcatcc attaataaaa tgttagctaa
    10861 atataagact accacaacta gcacgaatgg ccgaacggtg ccgtgtttac aggtagttgt
    10921 gtctcgagaa gataaacctc ctctagttgc aacgtggggt ggcataaaaa gaaagctgta
    10981 atagaagatg ctccgtatca agtttatggt ggtcgaacag agcttatcaa gcgattactc
    11041 gcaaataagt gtgagctatg tggaagtgag gagaacatag aggtacatca tatcagaaaa
    11101 ttagcagact tgaacaaaca caatgggaaa ttagttccaa agtggaaaga aatcatgtca
    11161 gcaagacgtc gaaaaatgct agtgacttgt cgggattgtc accatgcaat acataatggt
    11221 tcaataaata cacgtttatg aaatgaaatt actggagagc cggatgatgc gaaagtatca
    11281 tgtccggttc ggtgggggga taatggaaaa ggggtcgcaa tgactacctc gctagtatcc
    11341 taccctacac taatgatggt aaaaaacttg ccttagatca gcgtttaatt aatcctctgc
    11401 tacctgacaa tcctgacagt aaggtcaatg tctgtgtgaa aaatgtcttt agtatatggg
    11461 ataagacaaa agaagataag tcaacacagc tactattttc tgatatgtct acaccaaaag
    11521 gcgatggaga atttaacatc tatgatgata ttagagaaaa acttgtagca atgggaatac
    11581 caaaagaaga aatcgccttt atccacgaag cgaattccga taaacaaaag gacgaactct
    11641 ttgcaaaggt gcgtaaagga gatgtgagga tattacttgg ttctactcag aaaatgggag
    11701 ccggcacgaa tgtacaaaac aaactgattg cccttcatga tttggatgtt ccttggcgtc
    11761 ctgccgattt agagcagcgt gcgggcagaa ttgtaagaca gggcaatgaa aacaaggaag
    11821 taaatatcta tcgttatgtt acggagaaca cctttgatgc gtatttgtgg cagacaatag
    11881 agaataagca gaagttcatt tctcagatta tgacaagtaa aacacctgtc agagtggcag
    11941 aagatgtgga tgaaagttca cttaactatg cagaaattaa agcccttgcc acaggtgatc
    12001 cgaagattaa agaaaagatg gatttggata atgaggttac gaaacttaaa atgcttgaag
    12061 caaactataa gtccaaccgt tacagattag aggataaagt ggcgaaaaac tatcctgaag
    12121 aaatcgcaag aactgaaaag ctcatagaag ctgtcaagaa agatatatct gatgtagagc
    12181 ctaaagcgga cggagaggaa aagtttactt ctattactat cgcaggagca aagattaccg
    12241 ataagaaatt agcaggagaa agattgcttg aagctatttc aaaggttaaa atcaatgaaa
    12301 gtaaggtaat cggtaagtac agaaatatgg acttggaagc aagttataac ttctttacta
    12361 attctcataa tttcagctta aacggtgttg caaagcattc aggagagctt ggcacaagtg
    12421 ctgacggtaa tattacaaga cttgataacg ctcttgagaa aatgcctgag aaattaaaga
    12481 ggcttgaaga aaagctcata agcaccaaag agcagcttga aaatgccaaa gaggaattaa
    12541 aaaagccgtt tgaaaaagct gatgaattaa agagtaaggt gcttcgcttg gctgaactaa
    12601 ataagctact tgatatgggt gatgtggaag aaaagagaaa tgataatccc cttgtagaag
    12661 atgttaaaag ggcaattatt gatttctgta acagagaata tgaagaaaat catagctacg
    12721 atgagtttga tgctctatat cctgacttaa agcatatagg aattgcctat accaacacgc
    12781 cggatgaaag acacagcatt caatatgagc ttaatttaga ggataagata tggacacagt
    12841 atattgatga tatatctata aaaactgaga gctttgacta tgagaacaaa ggagagaatg
    12901 aaactctaag aaatatgaaa aatgagattg agctatcctc ttttgaagat ctggtttatg
    12961 tggattcaga agatttgaaa gcagcaacgg gacttgatat tgatgacgaa ggtaacttct
    13021 atgatccgct ttctaaagac cttgataatg acggaattac tgaccgttac gataatgact
    13081 ttaaggacag cgactatttt gaatcaacat atgatgtgga ggataatttt catagcaaag
    13141 aagaaagttc acaaaaatca gaggataagc catctatttt aggacagata agagcctatc
    13201 aggaagaaag taaaacagaa gaaaaacaaa ctacaaaaga acaggaattt ttaagataag
    13261 gggagggtaa cctccctttt actatgaaag gagataaaaa acatggatta caaaacaatg
    13321 agaaatcaaa tagaagatat ggcaaatgat aaccacaagg actttgtaaa agcgattata
    13381 agcgtggaga aaggtatcaa tgatgaaagt gctttggaca agctctatga cgcttatatg
    13441 gacaatgaca gtctgaattt actgcatgag gaatttgact acatgattga agatttacga
    13501 gaacaggggc aaataaaaga cctgccctat gttcaggaag agaaagataa tcttatcaat
    13561 atcgttggaa atattgtagg aaaggttgat gtagctgaaa gagaaaacaa gaatggagaa
    13621 gcctttaagg tggcaaattt ctctgttgta tctaaagatg atgagggaaa taaggtttat
    13681 cataattgct ccgcttatgg agaaaagagt gatattccaa aagactttaa gcagggagat
    13741 tttgtaaagc tctttggaca aatcagaact tccattgatg ataatggcaa ggagcatagc
    13801 aatgtaagga tactttcttc aaagctctta aaggcaaagg aacaaatgaa aggacaagaa
    13861 gaaaagaaag aatctgttct tggagctatc aagaaatatc agtctgaaga taaggaaaaa
    13921 ccaaaagaaa agagagacgc aagcaaagaa gctgagagat aaatatatgg tcggtgtggt
    13981 cttaggactg caccgactct tttttgtcta tctaaatgtc gtgtgtttgt gtaaaaggaa
    14041 gtttgtagtg aaaaaagtga ataaatatga tataatgata aaaacaaaat catatgcatg
    14101 ggaggacaat cgtgtcgaaa ataagttata aaaagctatt taaaaaaatg atagatttag
    14161 atatgaaaaa ttctgagcta atggaaaaag cagaagttag ccggagtact ttttataaaa
    14221 tgaagaacag tgagaatatt actactgatg tgattgtcag aatatgtgat agtttgaact
    14281 gtggtgtaaa tgaaattatg gagttggtgg atgatgaaaa taattgatta tgtaattgaa
    14341 tctacaaata aatatattaa acagatgcca aaagaaattc gcaagaaaaa tgggcaattt
    14401 ttcacaagta aagaaacagc tcttttcatg gcatcattat ttgatttatc atcattttca
    14461 aaagaaattt ctatactcga tccgggagcg ggttcaggaa tacttacggc agctcttatt
    14521 caaagaatta ttgatactga taagattgaa gccataaaaa ttacttgtta tgaaaccaat
    14581 gatgatattt tagagctgtt aaatgcaaat ttatcgtgga taagtaagaa tacatcacta
    14641 aaaattg
//
LOCUS       DARYYD010000046        14450 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.047, whole genome shotgun sequence.
ACCESSION   DARYYD010000046 DARYYD010000000
VERSION     DARYYD010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14450
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.047"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..1209
                     /locus_tag="TV188_001474"
     CDS             <1..1209
                     /locus_tag="TV188_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1534813.1"
                     /translation="LCLTFGGQFTIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVE
                     KIDDKKTEVKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKAYTSDT
                     IYTYEDYNLETKGMRLKDYEGHFFRGVPVNEYANNEERTGAYESVLDNIDAYDLSQSE
                     LANFQQDSVNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNP
                     NPNGVKPQAYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYK
                     LMASDNYREKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQND
                     NEIVTAAQNLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDAS
                     GQEEPTAEKP"
     gene            1169..2614
                     /locus_tag="TV188_001475"
     CDS             1169..2614
                     /locus_tag="TV188_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEL1534814.1"
                     /translation="MLVVKKNQRQKSLNYWQKRQKDILSYLDRTDLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEKDPELLK
                     RLNEQYVSARATRMDALNLELVYRAGILKGVLDSAFENHLKKAASYAYKKAMGGRSGT
                     INGPVLEELVRTPFDGYNYSEQLWGNTDNLVKNLQKKLKQGFVRGEHPRAIARDLAKQ
                     FNVANHRAETLIRTDGTMVINNATARRYLDAGLKYYRDLVRLDDRTTEICRKIAKENK
                     RKLLSELKPGINAAPYHFSCRTTLIPDEDELSIEVEPIDDKSTKYFKDVTSDWIDGNG
                     HKPQLSLLNEYVKNGTPYKVDGHNVVLDHSNYEYRVANWLSKKTGLQVDMVPRVNSPE
                     HINTPDYLVDGVPFDLKEITGSGKNVIDGNLRKAKKQATNIIFDITKTPLSFEEIMGQ
                     LEQIYMIDRRGLDISIIKNKDEVLAVLEKEG"
     gene            2645..2833
                     /locus_tag="TV188_001476"
     CDS             2645..2833
                     /locus_tag="TV188_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534815.1"
                     /translation="MGVRPSSFFISIIHHPIKTIKEENMFIWQMVLVALGVLVLILIV
                     GIAAIAVKSIIAELKKVG"
     gene            2836..3102
                     /locus_tag="TV188_001477"
     CDS             2836..3102
                     /locus_tag="TV188_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534816.1"
                     /translation="MNKRIKKKRKLETAVVMLVAENAMQAEAIKNQNKEIMELKSIVQ
                     RNALATNEEFASVKAATLDNQAAITNIAIDVNYIKKNYKRKWGK"
     gene            3258..3827
                     /locus_tag="TV188_001478"
     CDS             3258..3827
                     /locus_tag="TV188_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEL1534817.1"
                     /translation="MAEENVTTETTEQVDTQKEAVEHPKQEHERTFTRADISKMMAAE
                     RTKWESEQSEAIEKARTEGERLAKLSKDERAKEEEQKRLDAIAEREKAVAEREMRIET
                     HSLLVEKGLPLDFIDIVLATTAEEVKTNIDNLQTIFDKAVEKRVNDRLTQKPPRTGNG
                     SVGMTKADIMAIEDDDERMRLIAENRNLF"
     gene            3840..4727
                     /locus_tag="TV188_001479"
     CDS             3840..4727
                     /locus_tag="TV188_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEL1534818.1"
                     /translation="MAEKNLNTMADLGDIKSIDFVNKFSKNINDLLKLLGVTRRETLT
                     NDLKIQTYKWEVTLDQTDPGEGETIPLSKVTRTKDKDYTVKWFKKRRATTAEAIARHG
                     AARAITEADKRIMRELQNGIKDAFFTFLKTKPTKVKGVGLQKALSASWAKLATFNEFE
                     GSPLVSFVSPLDVANYLGDTKVGADASNVFGMTLLKNFLGMQNVIVMPSVPEGKIYST
                     AVENLVFASLNVKGGDLGGLFADFTDETGLIAAARNRQLSNLTYESVFFGANVLFAEI
                     PEGVVEATIEAAAVPGIGG"
     gene            4739..5095
                     /locus_tag="TV188_001480"
     CDS             4739..5095
                     /locus_tag="TV188_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HEL1534819.1"
                     /translation="MGDKQLIDDIKLFIGISKGDGAQDELITLAISESKERVLAKLNE
                     YSETEITKIPDRLRFIVRDVAIKRFNRINSEGTVEDSEEGKTFKWDSYLKEYESTLRS
                     AAIGKVYSGKGVARFI"
     gene            5106..5384
                     /locus_tag="TV188_001481"
     CDS             5106..5384
                     /locus_tag="TV188_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534820.1"
                     /translation="MIYKDRVILVYVDEQDDFLDKRTVEKPSGKIPCMENTFTKSEQM
                     GLFGKYDLNAFKLHLQGHYDGFSKIIYKGKPRLIKGLAHHKNSTVIYV"
     gene            5381..5725
                     /locus_tag="TV188_001482"
     CDS             5381..5725
                     /locus_tag="TV188_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEL1534821.1"
                     /translation="MSLIYRMRGLDRFLRSVERKQKSVRIAVDKELSKSAARIERQAK
                     ILAPVDTGWLRAQIYNEQQQLLHYRVVSPALYSVYIELGTRKMEAQPFLDPALRKEWP
                     VLMANLKKMFKR"
     gene            5729..6088
                     /locus_tag="TV188_001483"
     CDS             5729..6088
                     /locus_tag="TV188_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534822.1"
                     /translation="MDYSPETLYLKKVKNRLGVLDIPIYFKLPKSDVLEPFIVVGTNI
                     SDLSKTAQTGAVIDDFSLNIDAFLPGDSRLDAEEIKARMLRLLGRNNQIKAQILVDNS
                     IGREVYRVAINITETLF"
     gene            6100..6699
                     /locus_tag="TV188_001484"
     CDS             6100..6699
                     /locus_tag="TV188_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail protein, TP901-1 family"
                     /protein_id="HEL1534823.1"
                     /translation="MANTKEGTTIEITTGKPIVGKKIFYFIQSVDAKKGSKALLPAYR
                     TDGTTTMGGEYIDEQTQQGRVIEKATDEHSIDLTTYFVPTDPSVAVIEEAKKTGKSIK
                     IWEVIADESVKEQIQIPESSGPKKDVYPAKFGYAKIDEIERGTGISDLVEMSYTANIV
                     GALQDGKFPLTKEEIEMLENVYGYQNPGDTTGDYDNITK"
     gene            6753..7208
                     /locus_tag="TV188_001485"
     CDS             6753..7208
                     /locus_tag="TV188_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534824.1"
                     /translation="MEFTAAKRNIDIKFDFKTMFKINNKLGTINPETGERNADGVGAL
                     FFNILERNESAIVDLVRLSAGSGKKALTEDEILDAIAEAVDEEGTTEGLFAEIEKEMV
                     DSGFFRAKILKYIENMEKSARYLKAKDDTDATQIQIIEDMIGRMSNAVS"
     gene            7283..7516
                     /locus_tag="TV188_001486"
     CDS             7283..7516
                     /locus_tag="TV188_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534825.1"
                     /translation="MEGLEYKQVAERENLSELSLKLRYTLNAKKVDVGKLKYDKHRLT
                     IKRSYQKASRSQADSDSSIVERIQMLNNHFQNR"
     gene            7531..11688
                     /locus_tag="TV188_001487"
     CDS             7531..11688
                     /locus_tag="TV188_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEL1534826.1"
                     /translation="MPGTFDGSIFADVGANTKDYEQAMARIVSTTQNAFRKAQDTAVN
                     SSNKMVQIIGQIMAQLANNGESLGKRLGSAYATGLKLSIGEIQRIAASIGEKIPEPIK
                     NGFNKAFSIIQNSVQKLSSAIPHPIKSAFTSATSAVVSFSSKITSAVSAAFNSVSSKA
                     STVADKISSSFGGRITSAVTNLATKLSTGLSNGFSRMSSSAATSLNGISQKFANTSSA
                     GERLKSTVMSIVQAFSLMAVAQKAMHALTGAIGGAVSRVDTMNRFPKTMALFGYSAEQ
                     SKASIDKLSKGIEGLPTPLDSAVKSAQQLAITTGSLDKGTSLALAFNNAMIGYGATTE
                     GAEQALRQFNQSLGSGKIQAEEFNSVSEAAPGLMSKMAEAFGFGKNGVQDLKSALSDG
                     KITAQEFADKMIELNDAQGGFAEMAQSSAGGIRTAWKNVHTAVVKGVAGMISAFDEAA
                     KANGMKTIAETLLSLKPAITSVFDTINSLIPNAVAAFARLKQSINIDFSPLGASVKEV
                     FALINTVLGDFAHTGELSGQTFDKLKAKIASLAPKVIALWAVMNPASAIATIMPLLSL
                     FGKVGLALGSLGTSVGAFGGIISSGIASASGVVGAFAATLSGLPGVFATAAGRGLSVL
                     GTMTSAMSSLVSLALAAIGPAAILGLVVAGFGLINSQFGAQIDQLLNTAVTKGPGIIQ
                     GLVKGITSKIPALIASGTQLIAKFANAITVLLPVIIQAGVQLITSLVKGIGQNATSLI
                     SSAIKIIDSFVGSIMSALPQLISVGMELLLNVVNGIVQNIPLIIQQGQQIIDSFGNSL
                     RANLPSIISNGIAILVNLVQGITQMLPTVLQTATQVITSFVSGIVQFLPQLLQGGIQI
                     IISLVQGIIQNLPQIVQSAVQIIQSLVSGLTQALPQIIAAGIQLVVQLAVALIKGLPQ
                     IISAGIQLITGLGKAMLEAIPNALSGAWEGIKSGFSSMWDQITGKSSTSTAKVSADAT
                     AMALNVGTQTTAMANQANTDTTSMLNSISQNTELANINATSNATQMANNVNAQTGTMS
                     LQGLNDSMSLASGISANMSVANINATTQAQEMASGVNGATSSMNLDAINHTLSLASGV
                     GANMGTASTSATSQAQAMSSGVSNSLASMQSNSTKAASGLSNSVTSEMSSAATSATSS
                     ANRLSSAVESGFNKAKTSATTSMNGIANAVKTGFSSINSTAKQSMANLVSAVASGMSR
                     ATAVSNNACQKILSIFRALAGQMSSAGAYAGQGFANGLASSAGTIYAIANSIAANVAA
                     TIRRALDIHSPSRVTKTLGAFTGEGFALGMAEWIGEINSLGKAYATAVTDQNWGVNST
                     VSTSAKVNNSGINTSLDNLSEEVRQSQLSEPIFEVHNEIVGDKIYTAVKEKESREQSK
                     DSYFVFA"
     gene            11700..12542
                     /locus_tag="TV188_001488"
     CDS             11700..12542
                     /locus_tag="TV188_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1534827.1"
                     /translation="MDLLIEKESQATRLSDFGIYNIAIEDSAPLLSVSHRAVKGRSGY
                     IYDGATFTTKTLKVKGRVTVSDVEGVLDKQDELNALLVVDEPFYVTKMYPENSDLFNF
                     ELPGESTGDLQLIGSPHKPWKYRFKVILDDTITYEFIGKTSQGLKYNLSFTLRTAELP
                     FGETKPKDITLSGGSFAYGGTAKASQLEWPFIIELTPSGGQTNFYIEIDGRRFEFKQN
                     SQLQNSDKLLLTGIATTLNGNYVNAKTNYEYFIFNPNPNKRITYKTDFLGTIRILNFV
                     ELYK"
     gene            12552..>14450
                     /locus_tag="TV188_001489"
     CDS             12552..>14450
                     /locus_tag="TV188_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEL1534828.1"
                     /translation="MITFLDHRDIEYGAISVIRHTNAVNGERSVSGEIYTNSDVLNNI
                     DRGWRLRFEDEYYVVIYAKPVDVGQKTQVSFDAIHQFFWDFSKSSIYEGLGDGSHTID
                     TYLETVFKGSGYRYKLEVGVNAFRKQSFNYKSRLDLFNEIIKATGLEFSVSGKVVRLL
                     KNIGTDLSTVVRKNFNMNDLTIEKNIDSFITYQKGFGAWTDPEDHSKGRLEAEYESPL
                     AKEYGRLEGAPLTDERFTVADNLKEALKSNVENSYKISVKIDMEDLTRAGYRCERPVA
                     GDYIMAINETLGFQERIRIVSFTSYYDATGALVKHEVTCNDIGSVKKQSVGSLSINSR
                     INQIDADIASAIEVATQALVSADGKNTVYGGTEMPKDEPKGTLKKGDILFLKVGDTTR
                     MYFWNGAEWEEPEVVNDPERWREDLEKQISEAIEKAKKAQEEINQRTDKELEEFRAAL
                     KNLALPEEAIKKITEAIKVDDIPSIKQSFDDLKNRVSETSEESRLTAEILGNNGKTRY
                     NKNLLVGEPNRVKKIDEDFIEVEANDGGFKRGETYTISFSQTCEPLKKVAITLIQANN
                     KGVKLVLTPTKAKMEPETFTLIKDTEVINVYPLSYSVTLSGDWYKSKQVDLNASEVRN
                     MALGMSYRD"
BASE COUNT         4710 a         2562 c         3232 g         3946 t
ORIGIN      
        1 ttatgtctaa cttttggggg gcagttcact attgacctta tgtcggtcag aaacaatgag
       61 gactaccaca acgtcaaaat aaaaacagat ttatcaattt atggaagagc ctacgagctg
      121 ttaactgttg agaaaataga tgacaaaaaa accgaagtaa aactctacca gctcccggcc
      181 gagcaaactt ttgttatcta tgatgataca taccagcgaa attcgttgat ggccgttcat
      241 ttctacgaca tagattacgg ctcaggtaaa cgtaaacaga ttatcaaagc atatacttcc
      301 gacacaattt atacctacga agactataac cttgaaacaa aaggtatgcg attaaaagat
      361 tatgaaggac atttttttag aggtgtacca gtcaacgaat acgctaataa cgaggagcga
      421 acgggggctt atgagtctgt acttgataat attgacgcct atgatttatc tcaatcagag
      481 cttgctaact ttcaacaaga ttcagtcaat gcgttgcttg taatagctgg taatgcttac
      541 acaggagctg atgagaatga ctacttagat gatggccgat taaatcctaa tggtcgttta
      601 gcgatctcaa ttgggtttaa aaaagcccaa gtgttaattt tagacgataa tcctaatcca
      661 aatggcgtta aaccgcaagc gtactttctc aaaaaagagt atgataccgc cggtagcgaa
      721 gcctacaaaa atagattagt tgcagacatt ttgaggttta cttttacgcc agatacacaa
      781 gatatgaaat tttcaggagt tcaatctggt gaatcaatga agtataagct tatggcttct
      841 gacaactatc gcgagaagca agagaggttg tttaaaaaag gattaatgcg acgcttacgc
      901 ttagcagcta atatctgggc catcaaaggg aatgaagcaa ctacatatag ccttgtaaat
      961 gatacgagta tagttttcac acctaatctt cctcaaaacg ataatgaaat tgttacagct
     1021 gcacaaaatc tttatggcat tgttagcgat cagactatct ttgaaatctt aaatactgtc
     1081 acaggagtag atgctgaagc agagcttgaa cgcttgaaag aagaagctga taaaaagcaa
     1141 tctttaccgg agcctagatt ggtaggtgat gctagtggtc aagaagaacc aacggcagaa
     1201 aagccttaat tactggcaaa agcgtcaaaa agatattcta agttatttag acagaactga
     1261 tttagatgtc ttttcagaac tgcagaagtt atataatgaa caggcttttg agttacaaaa
     1321 ggaattgttt gatttttata ctaagtattc tgaagagaac aaaatgactt atcaggatgt
     1381 cgttaaaaaa ctacgtcatg aagatttatc agattacgta gctaatgcta acaagtatcg
     1441 taaacaagct gagaaagatc ctgagctgct aaaacgactt aatgagcagt atgtatcagc
     1501 aagagctaca aggatggatg cattaaatct tgaacttgtt tatcgcgcag ggatactaaa
     1561 aggtgtactt gattcagcat ttgaaaatca tttaaaaaaa gctgcctcat atgcttataa
     1621 aaaagcaatg ggtggacggt cagggacaat caatggtcca gttttagaag aactggttag
     1681 aaccccgttt gatggttata actactcaga acagttgtgg ggcaatactg acaatcttgt
     1741 caagaatctc caaaagaaat taaaacaagg ttttgttcgt ggcgagcatc ctagagcgat
     1801 agccagagat ttagctaagc aatttaatgt tgctaatcac agggctgaaa cactaatcag
     1861 aactgatgga actatggtga ttaataatgc taccgctagg cgctacttgg atgcaggact
     1921 taagtattat cgtgatttag ttaggcttga tgacaggaca actgagatat gtcgtaaaat
     1981 cgctaaagaa aacaaaagaa agctattatc tgagctaaag cctggaatta atgcagcacc
     2041 ttatcatttc agctgcagaa caacccttat tcctgatgaa gatgagctaa gcattgaagt
     2101 agaaccaatt gatgataaaa gcactaagta ttttaaggat gtcacctcag attggataga
     2161 tggaaatggg cataaaccac aactgtcact actaaatgag tatgtaaaaa atggcactcc
     2221 ttacaaagta gatggccata atgttgttct tgatcactcg aattatgaat atagagttgc
     2281 taattggtta tctaaaaaga caggattgca agttgacatg gtgccaagag ttaattcccc
     2341 tgaacatatc aatactcctg attatttagt tgatggagtt ccttttgatc taaaagaaat
     2401 cacaggttcg ggtaaaaacg tcattgatgg caatctacga aaagcaaaaa agcaggcaac
     2461 taatatcatt tttgatataa caaaaacccc tttatcattt gaagagataa tggggcagtt
     2521 agaacaaatt tatatgatag atcgtagggg tcttgatata tcaattatca aaaataaaga
     2581 tgaggtatta gctgtattag aaaaagaagg atgatgaccc accgcctcca cagtaaactg
     2641 cttcgtgggc gttagaccat catccttctt tatctcaatt atacatcacc ctattaaaac
     2701 tatcaaggag gaaaatatgt ttatttggca aatggtatta gtggcactag gtgtattggt
     2761 gctcatattg attgttggca ttgcagcaat agcggttaag tcaattattg cagaattgaa
     2821 aaaggtagga taaacatgaa taagcgcatt aagaaaaaac gtaagttgga aacagcggtt
     2881 gtgatgcttg ttgcagagaa tgccatgcaa gcagaagcaa ttaaaaatca aaacaaagaa
     2941 atcatggagt tgaaatcaat tgttcagcgg aacgctctgg caacaaacga agagtttgcg
     3001 tctgttaaag ctgctacttt agataatcaa gcagctatta caaacattgc aattgatgtt
     3061 aactacatta agaaaaatta taagcgtaag tggggaaaat aaattttaaa cgaattcgac
     3121 ccctttagaa atcaaagtcg tagcaatacg gcttttattg tgtccaaact ttgttgatga
     3181 cactaaaagc tacactgttt cgtcgcagga cgtaaagcta gactatcggt tggtggcgta
     3241 accactagga gaaagttatg gcagaagaga atgtaacaac agaaacaact gagcaagtcg
     3301 acactcaaaa agaagctgtt gaacatccta agcaggaaca tgagcgaact tttactcgcg
     3361 cagacatctc aaaaatgatg gctgccgaac gcactaaatg ggaatctgaa caatcagaag
     3421 ctattgaaaa agctcgtaca gagggtgaac gtttggccaa gttgtcaaaa gatgagcgcg
     3481 ctaaagagga ggaacaaaaa cgtctagatg ctatcgcaga gcgtgaaaaa gcagtagcag
     3541 agcgcgagat gcgcattgag acgcattccc tgcttgtgga gaaaggattg ccattggatt
     3601 ttattgatat tgttttagcc actactgcag aagaggttaa gaccaatatt gataatttac
     3661 aaactatttt tgataaagct gttgaaaaac gtgttaacga tcgtttaacc cagaagccac
     3721 cacgaactgg aaatggctcg gtcggcatga ccaaggctga catcatggca atagaggatg
     3781 atgacgaacg tatgcgttta attgctgaga atcgtaactt attttaagag aggaatatta
     3841 tggctgaaaa aaatttaaac actatggcgg acttaggaga tattaaatca attgattttg
     3901 ttaacaagtt ttccaaaaat attaatgatt tactaaaatt gctaggggtc actcgtcgtg
     3961 aaacattaac taacgatcta aaaattcaga cctataagtg ggaagtgact ttagatcaaa
     4021 ctgatcctgg agaaggggaa accatccctc tgtctaaggt tactcgaact aaagataaag
     4081 actatacagt gaagtggttc aagaaacgtc gtgcaactac agctgaggca attgctcgcc
     4141 atggcgcagc tcgtgctatt actgaagcag ataagcgcat tatgcgtgag cttcagaatg
     4201 gaattaagga tgcattcttt acattcctca aaacaaaacc aacaaaagtt aaaggcgttg
     4261 gccttcaaaa agcgctgtct gcatcatggg ctaagctagc tacttttaat gagtttgagg
     4321 gttccccgct tgtttctttt gtctctcctt tagacgtagc caactatctt ggagatacta
     4381 aagtaggtgc ggatgcctct aatgtttttg gaatgacatt gcttaagaac tttttgggta
     4441 tgcaaaatgt gattgttatg ccatctgtgc cagagggtaa aatctactca acggctgtag
     4501 agaatctagt ttttgcgtct ttaaatgtta aaggcggaga cttgggcggc ttgtttgctg
     4561 attttactga tgagacaggt ttaattgctg cagctcgtaa tcgtcagctt tctaatctta
     4621 cctatgaatc tgttttcttt ggggcgaatg tgctgtttgc tgaaattcct gaaggggttg
     4681 tagaggcaac aatcgaagct gctgctgtac ccggcattgg tggttaaagg ctatttatat
     4741 gggcgataaa caacttattg acgatatcaa actctttata ggtatttcca agggggatgg
     4801 tgcgcaagat gagctcatca cccttgctat atctgaaagt aaagagcgtg tgctagctaa
     4861 acttaatgaa tactcagaga ctgaaattac caaaattcct gatagattga ggtttattgt
     4921 ccgtgatgtt gccattaaac ggtttaatag gattaattca gaaggaaccg ttgaggatag
     4981 cgaagaagga aagactttta agtgggacag ttaccttaaa gagtatgaat caacactcag
     5041 aagcgctgct attgggaagg tatattcagg caaaggggta gcaagattta tttaggagat
     5101 acacaatgat ctataaagat agagtaatct tagtgtatgt cgatgagcag gacgattttc
     5161 tagataaaag aactgttgaa aaacctagcg ggaaaatccc ctgcatggaa aatactttca
     5221 caaaatctga acagatgggg ctatttggta aatatgattt gaatgctttt aagttgcact
     5281 tgcaaggcca ttacgacggc tttagcaaga ttatctacaa gggaaaaccg aggttgataa
     5341 agggactagc acaccataaa aatagcacgg ttatttatgt atgagtctta tttatcggat
     5401 gagaggctta gataggtttt tacgcagcgt tgagcgcaag cagaagtcag tacgaatcgc
     5461 tgtagataaa gagcttagca aatcagctgc tagaattgag agacaggcta aaatactagc
     5521 cccggttgat actggatggc tgagagctca aatctacaac gagcaacaac aactcttaca
     5581 ctatagagtg gtttctcctg ctttatattc tgtttatatt gaattaggta ctcgtaaaat
     5641 ggaagctcaa ccgtttttag accctgctct gagaaaagaa tggcctgtgc taatggctaa
     5701 tctcaaaaaa atgtttaaga ggtgatgcat ggattactca ccagaaacac tatatttaaa
     5761 aaaggtaaaa aatagattgg gagttttgga cataccaatc tattttaaat tgcctaaatc
     5821 agacgtttta gagcctttta ttgttgtggg tacaaatata tcagacttgt caaaaacagc
     5881 tcaaactgga gcagttattg acgattttag cctgaatatc gatgctttct tacctggcga
     5941 tagtcgtttg gatgcagaag agataaaagc tcgcatgctt agactgcttg ggcggaataa
     6001 ccaaataaag gctcagattt tggtagataa ttcaatagga cgagaagtct atagagttgc
     6061 tatcaacatt acagaaacac tattttaaag gagacctaaa tggcaaacac taaagaagga
     6121 acaactattg aaattacaac aggtaaaccg attgtaggga aaaagatttt ttatttcatc
     6181 caatcagttg acgctaaaaa agggagtaag gctttgctgc cagcctatcg taccgatggt
     6241 actacaacca tgggcggtga atacattgat gagcaaaccc aacaaggccg cgttattgag
     6301 aaggctacgg atgaacactc tattgatttg acaacgtact ttgtaccgac agatccatct
     6361 gttgctgtca tcgaggaagc taagaaaacg ggtaaatcta tcaaaatttg ggaagttatt
     6421 gccgacgaaa gcgtcaaaga acaaatccaa attcctgaat cgagtggtcc caagaaagat
     6481 gtttaccctg ctaagtttgg gtacgccaag attgacgaaa tcgaacgtgg tactggtatt
     6541 tcagacttag tagaaatgtc ctacaccgct aacattgtag gggccttaca agatggtaaa
     6601 ttccctctca cgaaagaaga aattgaaatg ctagaaaatg tatacggcta tcaaaatccg
     6661 ggtgatacta ctggcgacta cgataatatc actaagtagt acacaggggc ggcgactgct
     6721 gccccatttt gatttaaaaa ggagataaaa taatggaatt tacagcagcg aaacgaaata
     6781 tcgatattaa atttgatttt aaaactatgt ttaagatcaa taataaacta ggaacaatta
     6841 acccagaaac aggagagcgc aatgcagatg gtgttggtgc tttgtttttc aatatcttag
     6901 agcgtaatga aagcgccatt gttgaccttg tgcgtttatc tgcgggaagc ggaaaaaaag
     6961 cgctaactga agatgaaatt ctagatgcaa ttgcagaagc tgttgatgaa gaaggaacaa
     7021 cagaagggtt gtttgctgaa atagagaaag aaatggttga ttctggtttt ttcagagcga
     7081 agattttgaa atatatcgaa aacatggaga aatcagctcg ctatctcaaa gcgaaggacg
     7141 atacggacgc aactcaaatc caaattatcg aagacatgat tggaagaatg agcaacgcag
     7201 tatcttagta aattgcgcac ggttagggct cacagacatt gatactatct ataaatgtac
     7261 taagtgggag ctagaggcta ttatggaggg gcttgagtat aagcaggttg ctgagcgcga
     7321 gaacctctct gaattgtctc taaaacttag atatacatta aatgctaaaa aggttgatgt
     7381 aggtaagctc aaatatgata agcataggct aactatcaaa agatcgtatc aaaaagctag
     7441 ccgtagccaa gccgatagtg atagcagtat tgttgagaga atacaaatgc ttaataatca
     7501 ttttcaaaat agatagataa ggaggagtag atgccaggaa catttgatgg ttctattttc
     7561 gctgatgttg gtgccaacac aaaggactat gagcaggcca tggctcgtat tgttagtacg
     7621 actcagaatg ctttcagaaa agcccaagat acagcggtta acagtagtaa taaaatggtt
     7681 caaatcattg gacaaatcat ggcccaatta gcgaacaacg gcgaatcgct cggaaagaga
     7741 cttggttccg cctacgctac tggtttaaaa ctgagcattg gtgaaattca acgtatagca
     7801 gcttccattg gcgaaaaaat tcccgaaccc ataaagaatg gtttcaataa agctttttca
     7861 attatccaaa atagcgtaca gaagttatct agcgccatcc ctcaccccat aaaatccgca
     7921 ttcacaagtg caacaagtgc agtagttagc ttttcgtcta agatcacaag tgccgtctca
     7981 gcagctttca actctgttag ttctaaagcg agtactgttg cagataaaat cagtagtagt
     8041 tttgggggta gaatcacttc agcggttact aatttagcga ctaagttaag tacaggtctt
     8101 agcaatggtt ttagcagaat gtctagttct gcggctactt ccttgaatgg aatcagccag
     8161 aaattcgcca acacctcttc tgctggagag agactcaaaa gtacagtgat gagcatcgtg
     8221 caggccttta gtttaatggc tgttgctcaa aaagctatgc acgctcttac tggggcaata
     8281 ggcggggcgg ttagtcgggt tgataccatg aaccgctttc cgaaaacgat ggcactattt
     8341 gggtattctg ctgaacaatc taaggcatca attgataagt tgtcaaaagg aattgaaggt
     8401 ctgccaactc ccctagatag cgctgtgaaa agtgctcagc agctcgccat aaccacagga
     8461 agtttagata aaggaactag tttagccctc gccttcaata atgcaatgat cggttacggt
     8521 gcaacaactg aaggggctga gcaagcactc aggcagttta accagtcgtt ggggtctgga
     8581 aaaattcaag ctgaagagtt taactctgta tcagaagctg cgccgggttt aatgtctaaa
     8641 atggcggaag ccttcggttt tggtaaaaat ggcgtacaag atttaaaatc agccttatct
     8701 gatggcaaaa tcactgcaca agagttcgca gataaaatga ttgagcttaa cgatgcccaa
     8761 ggcggatttg cagagatggc ccaatcatcg gctggtggaa tccgaactgc gtggaagaac
     8821 gtacataccg ccgttgtaaa aggcgtagca ggtatgattt cagcctttga tgaagcggct
     8881 aaagctaatg gtatgaagac cattgctgaa acacttctta gcctgaagcc cgcaataacc
     8941 agcgtttttg atacgattaa ttctcttatt ccaaatgcag ttgcagcatt cgctaggcta
     9001 aaacagtcta tcaatattga ctttagccca ttaggcgcca gcgttaaaga ggtgtttgct
     9061 cttattaata ctgttcttgg agattttgca catactggtg aattatcagg acagactttt
     9121 gataagttaa aagcaaaaat tgcttcttta gcccctaaag tcattgccct ttgggcagtg
     9181 atgaaccctg ctagcgctat agcaacgata atgcctttgc tttctctatt cggaaaagtt
     9241 ggtctagctt taggaagttt agggacttct gtcggggcgt ttggtggcat aatttctagt
     9301 gggatagcta gtgccagcgg cgttgttggt gcctttgcgg caactctaag cggattacct
     9361 ggcgtttttg ctaccgcagc agggcgtggg ctatctgtgc ttggaactat gacaagcgca
     9421 atgtctagtc ttgtgagttt agcactggcg gccataggac cggccgctat tctaggtctt
     9481 gtggtggcag gatttggttt gattaatagt cagtttggcg cacaaatcga ccagctactt
     9541 aacaccgcag ttacaaaagg tcccggtatt attcaaggcc ttgtaaaagg gattacttct
     9601 aaaataccag ctttaatagc tagtggtact caattgattg ctaaatttgc aaatgctatc
     9661 acagtgttat taccagttat aattcaagcc ggcgttcagc taattaccag cctcgtcaaa
     9721 ggtattggac aaaacgcaac aagtttaatt agttcagcaa taaaaatcat tgatagtttt
     9781 gttggctcaa ttatgagtgc cttgccgcaa cttatttctg ttggaatgga gctattatta
     9841 aatgttgtca acggcatagt tcaaaatata cctcttatta tccagcaagg ccaacaaatc
     9901 attgatagtt ttgggaacag cttacgggct aaccttccta gtattattag caacggtata
     9961 gctattttgg tgaatcttgt acagggaatt actcaaatgt tgccaactgt tctgcagaca
    10021 gctactcaag ttattacgag ttttgtatct ggaattgtac agtttttacc gcagttactt
    10081 caaggtggca ttcaaatcat tattagcctt gtgcagggga ttattcaaaa tctaccccag
    10141 attgtacaat ctgctgtaca gattatacag tctttagttt ctggactgac gcaagctctg
    10201 cctcagatta tcgcagcggg cattcagctt gttgtacaac tagccgtagc cttgataaag
    10261 ggacttccac agattatttc tgcgggtatt caattaatta cgggactcgg taaagccatg
    10321 ttagaggcta tcccaaatgc tctttcagga gcttgggaag gtattaagag cggattcagt
    10381 tcgatgtggg atcaaatcac aggtaagagt tccacaagta cagctaaagt ctctgcggac
    10441 gccacggcca tggccttgaa tgttggtact caaacaacag ctatggctaa tcaagccaat
    10501 acagatacga catctatgct taatagcatt agtcaaaata cagagcttgc taatataaac
    10561 gctacatcaa atgctacaca gatggctaat aatgttaatg ctcagacagg aacgatgagt
    10621 cttcaggggt tgaatgattc aatgtctctt gcgagtggca ttagcgctaa tatgtctgtg
    10681 gctaatatta acgctactac tcaggctcaa gaaatggctt caggggttaa tggtgcgact
    10741 tcttcaatga atctagacgc cattaatcat acgctcagct tagctagtgg tgttggtgca
    10801 aacatgggaa ccgctagcac aagtgcaact tctcaggcgc aagctatgag ctcaggagtg
    10861 agtaacagtc tggcatcaat gcagtcaaac tcaactaaag cagcctctgg tctgtctaat
    10921 agcgtgacaa gtgaaatgtc ttctgcagca acctctgcaa cctcaagcgc caataggttg
    10981 tcctcggcgg tcgagtctgg cttcaataag gcgaagactt cagcaacaac ctcaatgaat
    11041 gggatagcca atgcggttaa aacaggattt agtagcatta acagtactgc aaagcaatct
    11101 atggcaaacc ttgtaagtgc agtggcttct gggatgtctc gtgcaaccgc ggtgtctaat
    11161 aatgcttgtc agaagatcct ctcaatattc agggctttgg cagggcagat gtcttctgca
    11221 ggagcttatg caggtcaagg ttttgctaat ggtctagcta gtagcgcagg cacaatctac
    11281 gcaatagcta acagcattgc cgctaacgta gcagcaacaa ttagacgcgc tctggatatt
    11341 cactcgccat ctcgtgtcac taaaacacta ggagcattta ctggagaggg gtttgccctc
    11401 ggtatggcag agtggatagg tgagatcaat agtctaggta aagcatacgc aacagcagtt
    11461 actgatcaaa actggggggt aaatagtact gtttcaacat ctgctaaagt taataatagt
    11521 ggaatcaata cctctcttga taatcttagc gaagaggtta ggcagtctca attgtcagag
    11581 cctatctttg aagtgcataa tgagattgtt ggagataaaa tttacacggc tgttaaagaa
    11641 aaagaatcaa gagagcaatc taaagattct tattttgttt ttgcctagaa gggagtattt
    11701 tggatttatt aatagaaaaa gagagtcagg caactagatt gtctgacttt ggtatttata
    11761 atattgctat tgaagatagt gctcctctac tatctgtatc acaccgagca gtcaaaggaa
    11821 ggagtggtta catctacgat ggggctactt ttacgactaa aacgcttaag gtcaaaggaa
    11881 gagtgacggt aagcgatgta gaaggagttt tggacaaaca ggacgaacta aacgctctgc
    11941 ttgttgttga cgaacctttc tacgtgacta agatgtaccc tgaaaactca gatctattta
    12001 actttgagct tccaggggaa agcacaggag acctgcaact tattggctct cctcataaac
    12061 cttggaaata tagatttaaa gtcatcttag acgacactat cacttatgaa tttataggaa
    12121 aaaccagtca aggactaaaa tataatcttt ccttcacact aagaactgct gaattacctt
    12181 tcggtgagac aaaaccaaag gacataactc tatcaggggg cagttttgcc tatggaggaa
    12241 ccgctaaagc aagtcagtta gagtggcctt ttattataga gcttactccc tctggaggtc
    12301 agactaattt ttatattgaa attgatggca ggcgctttga gtttaagcag aatagccagc
    12361 tacaaaatag tgataaatta cttttgacag gcatagctac cacactaaac ggaaattatg
    12421 tcaatgctaa aacgaactat gagtatttta tcttcaatcc taatcctaac aagagaatta
    12481 cttacaaaac ggattttctt ggcacgatta ggattttaaa ttttgtagag ttgtataaat
    12541 aggagggtct aatgattact tttttggatc atcgtgacat tgagtatggg gccattagtg
    12601 tcattaggca tactaatgct gttaatggtg agcgctcagt gagcggggaa atttatacaa
    12661 acagtgatgt cctcaataat atcgatagag ggtggcgact tagatttgaa gatgagtatt
    12721 acgttgttat ttacgcaaag cctgttgatg ttggtcaaaa aacgcaagtt tcgtttgatg
    12781 ccatacacca atttttttgg gacttcagca agagtagtat ctatgagggt ctcggagatg
    12841 ggtctcatac cattgatacc tatctagaga cagtatttaa aggtagtggg taccgctata
    12901 agctagaagt aggtgtgaac gcatttagaa aacaatcttt taattataag tccaggttag
    12961 atttattcaa tgagattatt aaagcgaccg gacttgaatt ttcagtcagc gggaaagttg
    13021 ttcggctatt aaaaaacata ggtactgatc tgtcaacagt ggtacgaaaa aatttcaaca
    13081 tgaatgacct taccattgaa aagaatattg atagctttat tacctatcag aaaggctttg
    13141 gtgcatggac cgacccagag gaccactcta aggggagact tgaggcggaa tacgaaagtc
    13201 ctcttgccaa ggagtacggt cgacttgaag gggcgcctct gacggatgag cgcttcacgg
    13261 tggcagataa tctaaaagaa gctttaaaaa gtaatgttga aaattcttat aagatatcag
    13321 taaaaattga tatggaagat ttaacgagag ctgggtatag atgtgagagg ccggttgctg
    13381 gtgactacat tatggcgata aatgagactt taggttttca agagcgtata cggatagttt
    13441 cttttacaag ctactacgac gcaactggag ctttagtaaa acatgaagtc acttgtaatg
    13501 atatcggatc tgtgaaaaaa caaagcgtag gaagtctgtc tataaacagt agaatcaatc
    13561 agatagatgc agatattgct tctgcaattg aagtagcaac acaagcacta gtatctgctg
    13621 acgggaaaaa tactgtttac ggtggcacag aaatgcccaa agatgaacca aaaggaacct
    13681 taaaaaaagg agacatatta ttcctaaaag ttggcgatac tactagaatg tatttctgga
    13741 atggtgctga gtgggaagaa cctgaggttg tgaacgaccc agaacgatgg cgtgaagacc
    13801 tcgaaaaaca aatctctgag gcgatcgaaa aagccaaaaa agcacaggaa gaaatcaacc
    13861 aacgcaccga taaagagctt gaagaattta gagccgccct caaaaaccta gcgttaccag
    13921 aggaagcgat taaaaaaatc acagaggcta taaaagttga tgacatcccg tctattaaac
    13981 aaagctttga tgacctcaaa aatagagtga gtgagacaag cgaagaatct cgtttaactg
    14041 ccgaaatttt agggaacaac ggtaagacac gctacaacaa aaatttgctg gtcggtgagc
    14101 ctaatcgtgt taaaaaaatt gatgaggatt ttatcgaggt agaagctaat gatggtggtt
    14161 tcaagcgtgg cgagacttac acaatcagct ttagtcagac atgtgagccg ctcaaaaaag
    14221 tggctatcac gctgatccaa gctaataata agggagttaa actggtactg acacctacta
    14281 aggcaaaaat ggagcctgag acttttactc taattaagga cacagaggtc atcaacgtct
    14341 atcctttgag ctactcagtc actttaagtg gtgactggta caaatctaag caagtagatt
    14401 taaatgcgtc ggaggtgcga aatatggctc tggggatgag ttatagagat
//
LOCUS       DARYYD010000047        14062 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.048, whole genome shotgun sequence.
ACCESSION   DARYYD010000047 DARYYD010000000
VERSION     DARYYD010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14062
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.048"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(81..1361)
                     /locus_tag="TV188_001490"
     CDS             complement(81..1361)
                     /locus_tag="TV188_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEL1534829.1"
                     /translation="MKIDKRHLLNYSILLPYLILSVIGLIMVYSTTSVSLIQAQANPF
                     RSVANQGLFWVVSLVAITFIYKLKLNFLTNTKVLTIVMLLEILLLIAARFFTTAINGA
                     HGWIVLGPLRFQPAEYLKIIMVWYLALTFSKMQEKIHQYDYQALTRRKWWPTEWGDLR
                     DWRVYSLIMIVLVAAQPDLGNASIIVLTAIIMFLVSGIGYRWFSAILVLITGLSTAFL
                     GMIAVIGVEKVAKIPVFGYVAKRFSAFFNPFRDLTDSGHQLANSYYAMSNGGWFGRGL
                     GNSIEKRGYLPEAQTDFVFSVVIEELGLIGAGLILALVFFLILRIMNVGIKAKNPFNA
                     MMALGVGGMMLMQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVGVGFVLNIDAN
                     EKKEDILKEAELSYRKSVREENSNSKIININQFQ"
     gene            complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TV188_001491"
     CDS             complement(1569..4352)
                     /gene="ppc"
                     /locus_tag="TV188_001491"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015055932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEL1534830.1"
                     /translation="MSVKKLESYNNQEIIAEEVAILKEILESITRRMIGDEAFARIEE
                     IIDLSEKQDYVLLEQLIAKISNKDMEFISRYFSILPLLINISEDVDLAYEINRQNNTN
                     QDYLGKLALTIASAAEKENAKELLERVTVVPVLTAHPTQVQRKTVLELTNSIHNLLRR
                     YRDVKAGVMNQNKWYSELYRYIDILMQTDIIREKKLKVKNEITNVMQYYNSSLIQAIT
                     ALTSKYKTLAKDKGILLDNPKPINMGMWIGGDRDGNPFVTAETLRLSATVQSEVILRF
                     YIDKLSALYQTFSLSSALTKTSPEVERLASLSSDQSIYRENEPYRRAFHYIQARLTQT
                     LQELIGQPASDQLASRMPATVGSLQSGVTRIVTNSSDQQAPAYKTAAAFKADLVMIEQ
                     SLIAAGDSSLVEGDLQEVLQAVDIFGFFLASIDLRQDSSVQEACVAELLKNAGIVENY
                     SALSEEQKCEVLLKELTEDPRTLSSAAVEKSELLEKELAIYTAARELKDKLGEEVIKQ
                     HIISHTESVSDMFELAIMLKEVGLVDQRQARVQIVPLFETIEDLDNARAIMTQYLSYD
                     IVKSWIATNAGYQEIMLGYSDSNKDGGYLASGWTLYKAQNELTKIGEDNGISITFFHG
                     RGGTVGRGGGPSYEAITSQPFGSIKDRIRLTEQGEIIENKYGNQDVAYYNLEMLISAS
                     INRMVTRMLTNPDEIDGFRKIMDEIVEDSNRIYRELVFDNPHFYDYFFEASPIKEVSS
                     LNIGSRPAARKTITDISGLRAIPWVFSWSQNRIMLPGWYAVGSAFKRFIDKEEGNLAK
                     LQHMYDKWPFFHSLLSNVDMVLSKSNMNIAFQYAQLAESKEVCEVFHTILDEWQLTKN
                     VILAIAQHDELLEETPSLKQSLDFRLPYFNVLNYIQIELIKRLRHEQLDEDYEKLIHT
                     TINGIATGLRNSG"
     gene            4550..6349
                     /gene="pepF"
                     /locus_tag="TV188_001492"
     CDS             4550..6349
                     /gene="pepF"
                     /locus_tag="TV188_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEL1534831.1"
                     /translation="MELKKRSEFPENELWDLTALYKDREDFLLAIEKALQDVGLFQRN
                     YEGKLTTAQDFTQALMEIEQIYIQMSHISTYAFMPQTTDFSDEAFAQIAQAGDDFMTK
                     ASVALSFFDTALANADLAVLDELEKNPYFSATIRMAKIQKEHLLSPDVEKALTNLREV
                     INAPYDIYTKMRAGDFEMEDFEVDGKVYKNSFVSYENFYQNHENAAIRDKAFRSFSNG
                     LRKHQNAAAAAYLAKVKSEKLLADMKGYASVFDYLLAEQEVDRSMFDRQIDLIMTEFG
                     PVAQKFLKHVARVNGLDKMTFADWKLDIDNALNPEVSIDGAYDLVMASLAPLGPAYTK
                     EVERYQTERWVDFAANANKDSGGYAADPYKVHPYVLMSWTGRMSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNTHMSTYYVEAPSTFNELMLSDYLEAQFDTPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGGTFGAEQLNAMMKDVLTEFWGDAVEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLNLKNNPNGANEWLDFLKSGGSRTPLETALLIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYTEEIGHD"
     gene            6342..6845
                     /locus_tag="TV188_001493"
     CDS             6342..6845
                     /locus_tag="TV188_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEL1534832.1"
                     /translation="MTSIYDFSVKRQDGTDCSLEQYQGKVLLVVNTATKCGLTPQYQA
                     LQELYDTYREQGFEILDFPCNQFLHQAPGDATEINAFCSLTYQTTFPRFAKIKVNGKE
                     TEPLFTWLKEQKSGPLGKCIEWNFAKFLIDQKGQVVERYASKTDPKMIEKALQQLLSQ
                     EPIDQSD"
     gene            7344..8537
                     /locus_tag="TV188_001494"
     CDS             7344..8537
                     /locus_tag="TV188_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1534833.1"
                     /translation="MRFQGLTSNFYNLIFSRSSRNIADSFYMIALSVGLLKVYNINAG
                     ELSFLTLVGLLPNMLSFAYGSLIHNLKNDKKWLIVFQMIQLIVIISIIICLSYQLPVV
                     VMYVLNLAFNLVTTVLNTIQMKIVPRTLDDDSDLIEKSVDIQYATSNVLDIVSNFVGS
                     VLLGFVSYLVLLQLSLPFFIGAIAFIFRIQLSPSKLSTTTNDEIEKPASVTESLRAFR
                     ESTFTSFIILVEAFLSGGTDLLLALLPLYLLSEGISIEYIGLVLAAHRAADLLGALVA
                     PRIKVSPRSFFFIDYILSGSSFLLCFMIPYPMVKLLLFFITFTIIGISGNVFEKMIYS
                     EYNHNKLALIYTTNATLYAVFGVLFLLIPFVYSNIRVIGIVINSLTIMIGFGLLIVHL
                     QQERK"
     gene            complement(8736..9200)
                     /locus_tag="TV188_001495"
     CDS             complement(8736..9200)
                     /locus_tag="TV188_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534834.1"
                     /translation="MLRLAFSGFLIGQPVMALLLIYLLYVNVAEAILAMTGYVLLLAC
                     FFGFGPWLFWQMACYSMVLVLWGYFLNPLSDRLSQHRLINQALMAGVCTFCYHILLDS
                     CFAYLYSISWWSYIWAGMLFTVTNALATMGYFLVVLLLLKRLSGKKDPKLSA"
     gene            9468..10316
                     /locus_tag="TV188_001496"
     CDS             9468..10316
                     /locus_tag="TV188_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEL1534835.1"
                     /translation="MRRRIKPIVVVVFFTLIATLLIIGKAHSDNLKSKELKLAKASIP
                     TNTSTSNKSTTSTSETTEFLLNPIIDVSGWQLPSDIDYDLLASNISAAIVRVYGGSQI
                     TAHNNAAFTTGIDKSFKKHITEFQKRHIPVAVYSYALGRSAKEMRAEARTFYKNASPF
                     NPTYYWIDVEEATMTDMNKGVKAFREELKRLGAENVGLYIGTYFMAEQDISTEGFDAI
                     WIPTYGGDSGYYEAAPDTSLDYDLHQYTSQGYLNGFNNPLDLNQIAVTKDTKKTFEKL
                     FGKVKP"
     regulatory      10725..10821
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            10868..11431
                     /gene="thiT"
                     /locus_tag="TV188_001497"
     CDS             10868..11431
                     /gene="thiT"
                     /locus_tag="TV188_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HEL1534836.1"
                     /translation="MSNKTTVTVLIEAAIFAALAMALSFIPDFAGWFSPSYGAIPLVL
                     FSLRRGLRYGLLTGLIWGLLHFILAKIYYLSLSQVIIEYILAFTSMGLAGLFSKPLTN
                     SLGTNKRSFSLLIASAAAFLAIGVRYIWHFIAGVIFWGSYAPKGTSAIWYSFTVNGTA
                     GLLTFIVTLIALLIILPTQPQFFKPSK"
     gene            11592..12071
                     /locus_tag="TV188_001498"
     CDS             11592..12071
                     /locus_tag="TV188_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEL1534837.1"
                     /translation="MAKKVKVKKTLVEQILDKAGIPYQALRINALQGDFPDTINPSDI
                     YKTLALTGDKTGPLIGIIPLTEHLSEKKLAGLSGNKKVSMIPQKELQKITGYVHGANN
                     PVGIRQRHNYPIYIDQSALAKQEIIVSAGELGRSIQINSQALADFVGASFADIKENK"
     gene            12068..12433
                     /locus_tag="TV188_001499"
     CDS             12068..12433
                     /locus_tag="TV188_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HEL1534838.1"
                     /translation="MRLIGNMIWFIFSGFWAWISWSIVGLILCLTIIGIPFGIQCFKI
                     GALGLFPFGKAIEIGQGAGSLLLNIIWIVCCGWSLAIMHLTSALLLCLTIVGIPFARQ
                     SLKLAKISLFPFGAIIYDI"
     gene            12452..13096
                     /locus_tag="TV188_001500"
     CDS             12452..13096
                     /locus_tag="TV188_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEL1534839.1"
                     /translation="MKLYFVRHGKTLWNLEGRFQGANGDSPLLESSKDDLRQLARELW
                     DISFDAIYSSDLKRAVDTARIIVDEANCKTDISYTKQLREWNLGTLEGTKIATVSAIY
                     PSQMSAFYHNLAKFKPSQFKAESLYESTQRLYQLIKSLEDKAYQQVLMVGHGAHLTAS
                     IRALLGFEPGMLRAQGGLDNASLTVIETLDFKHFHCLRWNDTSFLQKKTTRLTP"
     gene            complement(13527..13694)
                     /locus_tag="TV188_001501"
                     /pseudo
     CDS             complement(13527..13694)
                     /locus_tag="TV188_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270424.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
BASE COUNT         4228 a         3073 c         2663 g         4098 t
ORIGIN      
        1 caactttttg ggggcagtac acctggtcct ctctaaatgt ttgttataag ccacccgcta
       61 cagttgacaa ggagcttttt ttactgaaat tgattaatat taataatctt actattacta
      121 ttttcttccc ggacagactt ccggtaagat agctctgctt cttttaaaat atcctctttc
      181 ttctcattgg catcaatatt gaggacaaag ccaaccccta cagacaagac cagcaggctg
      241 tttcctccct gtgataagaa tggaaaggta acccctgttg aaggaatgag gccagaaatg
      301 ccaccaatgt taacaaatac ctgcatcagc atcatgccac caacaccaag agccatcatg
      361 gcgttaaagg gatttttggc cttaatcccg acattcatga ttctcaaaat aagaaagaaa
      421 acaagcgcaa ggatcaatcc tgccccaatc agccctaact cctcaatcac gacagaaaag
      481 acaaaatctg tctgtgcctc tgggagatag ccccgctttt caatcgaatt tccaagccct
      541 ctgccaaacc agccaccatt gctcatggcg taataagaat tagccagctg atgtcccgaa
      601 tctgtcaaat cacgaaaagg attgaaaaaa gcactaaagc gcttggcaac gtaaccaaaa
      661 actggaatct tagccacctt ttcaacacca atgacagcaa tcattcccaa aaaagcagtt
      721 gacaaaccag taattagcac taaaatggca gaaaaccaac ggtagcctat accactgacc
      781 aaaaacatga taatagctgt caacacgata atagaggcat tgcccaaatc aggctgcgca
      841 gcaaccagca caatcataat caaggaataa acacgccaat cacgcaggtc accccactct
      901 gttggccacc atttgcgacg cgtcaaggcc tgataatcat actgatgaat cttttcctgc
      961 atctttgaaa aggtgagtgc cagataccaa accatgatga tcttcagata ctctgctggc
     1021 tgaaacctca gaggcccaag gacaatccag ccatgcgcgc cattaatcgc tgtcgtaaaa
     1081 aagcgagcag caatcaacag cagtatttca agcagcataa caattgttaa aaccttggta
     1141 ttggtcaaaa aatttagctt tagcttgtaa ataaaggtaa tagcaactaa gctgacaacc
     1201 caaaagagcc cttgattggc aactgaccga aatggattgg cctgagcctg aatcaagcta
     1261 acactggttg tggaataaac catgatcagc ccaatcacag ataaaatcag ataaggtagt
     1321 aatatggagt aatttagcaa atgcctttta tcaattttca tcatttcccc tataatcttg
     1381 agataatcat tagcattata tcatctttca ttggtaaaac aaaggaaaaa tacattgcaa
     1441 gcacctagcc aagcatggct ctagacaaag cttgctgtat ccttggaatc gctcaatcta
     1501 aaaaacacag acaagccatt ataacctagt agcctgtctg tgtgagctgc tgattgatct
     1561 tcaacggctt agccggaatt acgaagtcct gtagcaatac cattaatagt tgtgtggatc
     1621 agcttttcat agtcctcatc tagctgctca tgacgaagac gcttaatcag ctcaatctga
     1681 atgtagttta acacattaaa atatgggagg cggaaatcca agctttgctt caaggacggg
     1741 gtttcctcaa gaagctcatc atgctgtgcg atagcaagaa taacgttctt agtcagctgc
     1801 cactcatcaa gaatggtatg aaagacctca cagacctcct tgctttctgc taactgcgca
     1861 tattgaaagg caatgttcat gtttgatttt gataatacca tatcaacatt agacagcaag
     1921 gaatgaaaga acggccattt gtcatacata tgctgtaatt tggctaaatt tccctcttct
     1981 ttatcaataa aacgcttaaa ggcagagcct actgcatacc agcctggaag catgatccgg
     2041 ttttgtgacc aagaaaatac ccaaggaatg gcacgcaggc ctgagatatc tgtaatggtt
     2101 ttacgagcag cagggcgaga accaatattt aagcttgata cctccttgat cggactggct
     2161 tcaaagaaat aatcatagaa atgcggattg tcaaaaacca gctctcgata aatgcgatta
     2221 ctgtcttcaa caatttcatc catgattttc ctaaagccat caatctcatc aggatttgtc
     2281 agcatacgag tcaccatgcg attgatagaa gcagaaatca gcatttccaa attgtagtaa
     2341 gccacatctt gattgccata tttattttca ataatctcac cctgttccgt caagcggatt
     2401 cggtctttaa tagagccaaa tggctgtgag gtgatcgcct cataggatgg accgccacca
     2461 cgtccaacag tcccaccacg tccatgaaag aaggtgatgc tgataccatt gtcctcccca
     2521 attttggtca gctcattttg cgccttgtaa agtgtccagc cagacgctaa atagccaccg
     2581 tctttgttgc tatctgaata cccaagcata atctcttgat agccagcatt tgtagcaatc
     2641 caagacttga caatatcata gctaaggtat tgtgtcatga tcgctctagc attatccaaa
     2701 tcctcaatcg tttcaaataa aggcacaatc tgcacacgcg cctgacgctg gtcaacgaga
     2761 ccaacctcct ttagcatgat agccagctca aacatatcag aaacactctc tgtatgtgaa
     2821 atgatgtgct gcttaatcac ctcttcacca agcttatcct tgagctcacg tgccgctgta
     2881 tagatagcaa gctccttttc taacagctct gacttttcaa cagctgccga tgagagggtg
     2941 cgagggtctt ctgtcagctc ctttaagagg acctcacatt tttgctcctc tgacaaagca
     3001 ctgtaattct caacaatacc agcatttttc aaaagctcag caacacaggc ctcctgcaca
     3061 ctagaatcct gccgcagatc aatactggct aaaaagaaac caaaaatatc aaccgcttgt
     3121 aggacctctt gcaaatcccc ctcaaccaag gaggaatccc cagctgcaat gagagattgc
     3181 tcaatcatga ccagatcagc cttaaaagct gctgctgtct tataggctgg tgcttgctgg
     3241 tcactgctat tggtcacaat tcttgtaacg cccgactgaa gcgagcctac cgtagcaggc
     3301 attctagatg ctagctggtc tgaggccggc tgaccaatta gctcctgcaa ggtttgggtt
     3361 agacgagcct gaatatagtg aaaagctctg cggtagggct cattctcacg ataaatggac
     3421 tgatcactag atagactggc cagacgctcc acctcaggac tggtctttgt caaggctgac
     3481 gacagcgaaa aggtttgata aagagctgac aatttgtcaa tgtaaaagcg caggataacc
     3541 tcactttgga ctgttgcaga cagcctcagt gtctctgctg tgacaaaagg attgccatct
     3601 cggtcccctc cgatccacat gcccatgtta atcggctttg gattgtccag caagatcccc
     3661 ttgtccttgg ccagcgtctt atacttgctt gtcagcgctg tgatcgcctg tatcagagag
     3721 ctattgtaat actgcatgac attggtaatc tcatttttga ccttgagctt tttctcacga
     3781 atgatatccg tctgcatgag aatatcaatg taacggtaca gctcactata ccatttgttt
     3841 tgattcatga cacccgcctt gacatcacga tagcgacgaa gaaggttatg aatgctattg
     3901 gtcaactcta gaactgtctt tcgctgaacc tgtgttgggt gagctgtcaa gactggaacc
     3961 accgtcaccc tttccaacag ttccttggca ttttcctttt cagcagcaga agcaatggtc
     4021 agagcaagct ttcccagata gtcttgattt gtattgtttt gacgattgat ttcataagcc
     4081 aaatcaacgt cctctgaaat attaatcaac agcggaagaa tcgaaaaata tcgtgaaata
     4141 aattccatat ctttattgct aatcttagcg atcaattgct ctagaagcac ataatcctgt
     4201 ttttcagata ggtctataat ttcctcaatc cttgcaaagg cctcatcacc aatcatgcga
     4261 cgcgtaatgc tctcaagtat ttcctttagg atagcaacct cttcagcaat aatctcctga
     4321 ttattatagc tctctaattt tttgactgac aaatgacgga cttcccttct tatgctagtt
     4381 ttcctcctat cataccactt tttgctaaaa atgtaagcct attggctagg aatgtttgtt
     4441 ttccttgaca tataagattc attggtacaa aaatgtttgt aaagctttta caggctatcg
     4501 cttctaattt ttgttatact ataggtaatt actcatgaag gagaacatta tggaattaaa
     4561 aaaacgttca gaattccctg aaaatgagct ttgggaccta actgccctct acaaagacag
     4621 ggaagatttt ctattggcca ttgaaaaagc cttacaagat gtcggcctat tccaacgcaa
     4681 ttacgaaggc aaattaacaa ctgctcagga ttttacacag gccttgatgg agattgagca
     4741 gatttatatt caaatgagtc atattagcac ctatgccttt atgccacaga ccactgattt
     4801 ttcagatgaa gcatttgctc aaattgccca ggctggtgat gattttatga ccaaggctag
     4861 cgtagccctc agcttctttg atacagccct agctaatgca gaccttgctg ttcttgatga
     4921 attggaaaaa aatccctatt tcagcgcaac tatccgcatg gcgaaaatcc aaaaagagca
     4981 tttgctaagc cctgatgttg aaaaggcact gaccaatcta cgagaagtga tcaacgctcc
     5041 ttacgacatt tacaccaaaa tgcgggctgg agattttgag atggaggatt ttgaagttga
     5101 tggtaaagtc tacaaaaata gctttgtttc ctatgaaaac ttttatcaaa accatgaaaa
     5161 tgctgccatt cgtgacaagg cctttcgttc cttctcaaac ggactgcgta agcaccaaaa
     5221 tgcagcagcc gcagcctatc ttgctaaggt caaatcagaa aagctcttag ctgatatgaa
     5281 gggctatgcg tctgtttttg attacctgct ggctgagcag gaggtggacc gcagcatgtt
     5341 tgaccgtcaa atcgacctca tcatgaccga atttggtcca gttgctcaaa aattcttaaa
     5401 gcatgtggca agggtaaatg gcttagacaa gatgactttt gcagactgga agctagatat
     5461 tgataacgcc ctcaatccag aggtctctat tgatggagct tatgacttgg tgatggcatc
     5521 attagcacca cttggtccag cctatacgaa agaagttgaa cgctaccaaa cagagcgctg
     5581 ggtggacttt gctgcaaatg ccaataagga ttctggtggc tacgctgctg acccttacaa
     5641 ggttcaccct tatgtgctga tgagctggac aggccgtatg tctgacgttt acacgctgat
     5701 ccatgagatt ggccattctg gtcagtttat cttctctgac aatcaccaaa gctacttcaa
     5761 cacacacatg tcaacctatt acgttgaagc accttcaacc ttcaatgagc tgatgctaag
     5821 tgattatttg gaggcacaat ttgacacgcc tcgtcaaaaa cgctttgcac tggcgcaccg
     5881 cttgacagat acttatttcc acaacttcat cacgcatttg ttagaggctg cctttcagcg
     5941 taaggtttat accctcatcg aagagggggg cacctttggt gcagagcagc ttaatgccat
     6001 gatgaaggac gttttaacag agttctgggg cgatgctgtt gagattgatg atgacgctgc
     6061 ccttacctgg atgaggcagg ctcattatta catggggctt tatagctata cctattctgc
     6121 agggcttgtg atttcgactg ccggctacct caatctaaag aataacccaa atggtgccaa
     6181 cgaatggctt gatttcttaa agtctggtgg cagtcgtacc ccgcttgaga cagccctact
     6241 catcggagct gacatctcaa cagacaagcc gcttcgcgat accattcaat tcttgagcga
     6301 tacggttgat cagatcattg cctatacaga ggaaattggt catgactagc atttatgact
     6361 ttagcgttaa aagacaagat ggcactgatt gttcactgga gcaataccaa ggaaaggtcc
     6421 tattagtggt caacaccgcc actaaatgcg gattaactcc tcaatatcaa gcattacaag
     6481 agctttatga cacctacagg gaacaaggct ttgaaatcct tgatttcccc tgcaatcaat
     6541 ttttacatca ggcaccgggt gatgctacag aaatcaatgc cttttgcagc ttaacttacc
     6601 agaccacctt cccacgcttt gccaaaatca aggtcaacgg caaggagaca gagccattat
     6661 tcacttggct caaagaacaa aaaagtggcc cactcggcaa gtgcatcgaa tggaacttcg
     6721 caaaattttt aattgatcaa aaggggcagg ttgttgagcg ctatgcctca aaaacagacc
     6781 ccaaaatgat tgaaaaagcc ctacagcaat tgctttccca agagccaatt gaccaatcag
     6841 actaacgaag tcctatcaaa aaacaagcca agatccttat ttcttggctt gtttttatat
     6901 ctaaagcttc ttgctttgcc gaggagccgc taaaggtcgg ctatttgctt gtctattctt
     6961 caaagaactt ttttgaaggg gaccttgtcc tcacacctaa gcttactttt ttcaatcaaa
     7021 tcattcaagc tgcttcctgt aaggactggt gcacttgagc aatgataact tatgctagcc
     7081 tttttatgtt tatcaaaaag tacctgttca catgatttaa ggacatttac ttcagtcatc
     7141 aacagtaaaa agcattgacg catgtgatta ggattgttaa aatcatctta taaaattaag
     7201 aaaaacacat gactattgaa tgatctaagc tgtgctgcca aaagccctta cccttaatcc
     7261 tatcacagtg gacagcatgc aaatgacctc aggagtttca aatgacattc aaatagattg
     7321 tactgattgg agagtttatc agcatgagat ttcaagggtt aacaagtaac ttttataacc
     7381 tcatttttag taggtcaagt cgcaatatcg cagacagttt ttacatgatt gctttgtctg
     7441 ttggtttact taaggtttac aacattaacg cgggagaact ttcttttttg acattggttg
     7501 gtttattgcc aaatatgctg tcttttgctt atggttcttt aatccataac ttaaaaaatg
     7561 ataaaaaatg gttaattgtc tttcagatga tacagctcat tgtcatcatc agtattatca
     7621 tctgcttaag ctatcagcta ccggttgttg tcatgtatgt gctcaacctt gcctttaact
     7681 tggtcacaac cgtattaaat accattcaaa tgaaaatcgt tcccagaaca ctagacgatg
     7741 attcagacct cattgaaaaa tcagtagata ttcaatatgc tacatcaaac gttctagata
     7801 ttgttagcaa ttttgtgggc tctgttcttc ttggctttgt ttcctatctc gttttactgc
     7861 aattgagcct gcctttcttt ataggagcca tagcttttat ttttaggatt cagcttagcc
     7921 cgtctaagct tagcaccacg actaatgacg agattgaaaa acctgcttct gtaacagaat
     7981 cactacgtgc atttagagag tcgaccttta cttcctttat catcttggta gaagcctttc
     8041 tcagtggagg aaccgattta ttactagcac tccttccatt gtatctactg tctgagggca
     8101 tttcaatcga atacattggc cttgttttag cagctcacag agcagcagat ttattagggg
     8161 ctctggttgc acctcgcatt aaggtatctc cacgaagctt ctttttcatt gattatatcc
     8221 tgtctggaag cagcttcttg ctttgcttta tgattcccta tccgatggta aaattacttt
     8281 tgtttttcat taccttcacg attattggca tatcgggcaa tgtatttgaa aaaatgattt
     8341 atagtgagta taaccacaac aagctcgcct tgatctacac gaccaatgca accttatacg
     8401 ctgtctttgg tgtcctattt ttactgattc cctttgttta tagcaacata agggttatag
     8461 gaatcgtgat caacagcctg acaataatga taggatttgg attactcatc gtccatttac
     8521 agcaagaaag aaaatagctt agttctaaaa ccagcaaaat ggataaagcc cttcaacaaa
     8581 ataagcttcc ttacaaaaag gaatcagaag tcactattaa ataatcaaaa actatcaatc
     8641 gatataagaa gatttaagga gcaaaaaaaa gaaattactg atcggcaaca actgcactac
     8701 taccgggttg ctgcgtcaaa gccagcatta agaccctaag ctgacagctt agggtctttt
     8761 ttgccagata gccttttaag caataaaagc actaccagga aataacccat agtggctaag
     8821 gcattagtca ctgtaaaaag cattcctgcc catatatagc tccaccaaga gatactatag
     8881 aggtaagcaa aacaactatc tagcagtata tgatagcaaa aggtacagac tcctgccatt
     8941 aaggcttgat tgatcaaccg gtgctgcgat agcctgtctg ataagggatt caagaaatac
     9001 ccccacaaaa ccaataccat tgaataacaa gccatttgcc aaaagagcca aggaccaaag
     9061 ccaaaaaagc aggctaataa gagcacatag cccgtcatcg ctaaaatagc ctctgctaca
     9121 ttaacataga gtaggtaaat caacaaaaga gccatgactg gctggccaat gagaaagccg
     9181 ctaaaggcta ggcgcagcaa gaagcaacat acagaaacga tagctagtcg actaataact
     9241 ttggtagaca taatccctct ttgagtgttt tttatctatt atgacagatt ttgcatctct
     9301 tgaccagcat caacagcttt ttgatagatg attacaagac aggtagacta aaatcaaacg
     9361 aaaatagata ggacctgatc tgccaaagct gtcctaagga gctaaaaacc taagaaaatc
     9421 gtaagaccac tttgattttt tgaagcattt aaggtacaat aagactgatg agaagaagaa
     9481 taaaacctat tgttgttgtg gtcttcttta cgctgattgc tactttgtta atcattggaa
     9541 aggctcattc tgataatctc aaaagtaaag agctaaagct tgctaaagca agcattccca
     9601 ctaacactag cacgtccaat aagtcgacta caagcacatc tgaaactact gaatttctac
     9661 taaaccccat tattgatgtt tctggctggc agctgccaag tgacattgat tatgaccttt
     9721 tagcatctaa tatttctgca gcaattgttc gtgtttatgg cggatcacaa attactgccc
     9781 ataataacgc tgcctttact accgggattg ataaatcatt caaaaagcat attactgaat
     9841 ttcaaaaacg acatatccca gttgctgtct atagctatgc tctaggtcgt agtgccaagg
     9901 aaatgcgagc tgaagcaaga accttttaca aaaacgcttc tccttttaac ccaacctatt
     9961 attggattga tgttgaagaa gctaccatga cagacatgaa taaaggggtc aaggcgttta
    10021 gagaggagct aaaacggtta ggtgcagaaa atgttggcct gtatatcggt acttatttta
    10081 tggccgagca ggacatttca acagaaggct ttgacgccat ctggattcct acctacggtg
    10141 gtgattctgg ctattatgag gcagcgccag ataccagcct agattacgac ctgcatcaat
    10201 atacctcaca aggctacctc aatggcttta acaatccatt agatttaaat caaatcgctg
    10261 tcacaaaaga cactaaaaaa acctttgaaa agctttttgg gaaagtaaag ccttaaaggc
    10321 atcgaagcaa gtcgtcaaaa cctttgaatg tcagtcattc cgaatgcctt aaaccctaag
    10381 ctcaaagccc aggtaagcca atcctaaaga aggttgctcc tattcttatt tctttaagaa
    10441 taaagaccct ttcatcaatc taagaaggct aaagattgct ggctgttaaa aaatgctata
    10501 ttgattcctt ctgacgtcaa tttgagcatt aaggacaact gtatttagaa gctgatattg
    10561 ataacaccaa tcactgcttg tttttggttt aaaggctggc tgttagctca gccttttttg
    10621 gtgtgatcag tttttgacta taccgctatg ccaactttgt ctcatgattt caaggccaaa
    10681 ttcttgacat tgctgccatc tcattttata atatagaaaa tataattatc acaaaggagt
    10741 gctttggctg agatcgcgta tgcgaaatcc taaggacctg atcttgttaa tacaagcgta
    10801 gggattgtga ccaatatcat tagcattgga aaacgattct ctttttgtgt gcaaaaggag
    10861 tttttttatg tcaaacaaga caactgttac tgttctgatt gaggctgcta tttttgctgc
    10921 tcttgctatg gctttatcat ttataccaga ttttgccggc tggtttagcc cctcttatgg
    10981 tgctattcct ctcgtcttat tttcgcttag gcgtggcctc aggtatggcc tgctaactgg
    11041 cttgatttgg gggctgctcc attttatttt agcaaagatt tactacctca gtctatctca
    11101 ggttattatt gaatatatcc ttgcctttac ctcaatgggc ttagctggcc tgttttctaa
    11161 gcccttgact aatagtctag gtaccaataa aagatccttc agccttctaa ttgctagcgc
    11221 agctgccttt ttagcgattg gggttcgtta tatctggcat tttatcgctg gtgttatttt
    11281 ctgggggagc tatgctccta agggcacctc tgctatttgg tattccttta ctgtcaatgg
    11341 cacagcaggt cttctaacct ttatcgtgac acttattgcc ctgctcatta tcctaccgac
    11401 acaaccacaa ttttttaagc ctagtaaata agacaagagt tcgaatcgga aaatcataaa
    11461 gctgaggcag gtctgtaaag gcctgctctt tctaagccta gaaaaaggat caaaaaagac
    11521 tttttttcag tctaatggta tactactact gttagactgt ttttgatatt gacacataag
    11581 gaagttaaca aatggctaaa aaggtaaaag taaagaaaac gctggtggag caaatcctag
    11641 acaaggcagg tatcccctat caagcgctta ggatcaatgc cttacaaggt gatttcccag
    11701 acacaatcaa cccatcagat atttataaaa ccctagcact gactggcgat aagacaggcc
    11761 ccttgattgg gattattcct ttgacagagc atttatctga aaagaagcta gcaggccttt
    11821 ctggaaacaa aaaggtctcc atgattcctc aaaaggagct gcaaaaaata accggctatg
    11881 ttcatggtgc aaacaatcca gttggtattc gacaaaggca caattaccct atttacatcg
    11941 accagtctgc actagccaag caagaaatta tcgtatcagc tggtgagctt ggtcgatcca
    12001 tacagatcaa tagtcaagcc ctagcagatt ttgttggggc tagctttgct gacataaagg
    12061 agaacaaatg agacttattg gaaatatgat ttggtttatt ttttcaggct tttgggcctg
    12121 gatttcttgg tctattgttg ggcttatcct atgcttaaca attatcggga ttccttttgg
    12181 gatacaatgc ttcaagatag gcgctttggg tctttttcct tttggaaaag ccatcgaaat
    12241 tggccaagga gcaggcagcc tgctgctcaa tatcatctgg attgtctgct gtggctggag
    12301 cttagcgatc atgcatttga cttctgccct tctcttgtgc ctcacgattg ttggcattcc
    12361 atttgcccgg caatctctaa aattggccaa gattagcctc tttccttttg gagccatcat
    12421 ttatgacatt taattaggaa gcaaaagact tatgaaattg tattttgtca gacatggtaa
    12481 aaccttgtgg aacctagagg gccgttttca gggagctaac ggagattcgc ccttgcttga
    12541 aagctctaag gacgatttgc gccagctagc aagagagctg tgggacattt cttttgatgc
    12601 gatctactcc agcgacctaa aaagagctgt tgatactgct cgcattattg tggacgaagc
    12661 taactgcaag actgatatta gttataccaa gcagctgaga gaatggaacc taggcaccct
    12721 ggaaggaacc aaaatagcaa ctgtatccgc catctacccc agtcagatgt cagcctttta
    12781 tcacaattta gccaaattca agcccagtca atttaaggct gaatcccttt atgaaagcac
    12841 acaaaggctt tatcagctca ttaaaagttt ggaagataag gcctatcagc aggttttaat
    12901 ggtaggacat ggcgcccatt tgacagcttc tattcgtgct cttttaggct ttgagccagg
    12961 tatgcttcgg gcacagggag gactggataa tgccagccta accgttatag aaaccttgga
    13021 tttcaaacac tttcattgtc taaggtggaa tgatacatca tttttacaaa aaaagactac
    13081 tagattaaca ccctagtagc tcttaagcac aaagctccaa gacagctaaa ctgtactcca
    13141 ttggttagag aacacatctc attttttgag ggacgcttta ttagctgtag gaagttatga
    13201 aaagctaaat acacgagagg actaaattgg acaagctcaa aagtttgaca atgtatttca
    13261 aaaaaggatt gaattctgta tcgaacagga ctcagtcctt tttatcattt atcaagccga
    13321 ccaaggcttt caaccacgac aaacgcgcaa aacagttatt tcctgatgat agtagagact
    13381 acagcagata ttttcaatga ttttcttgta gtaacatcta tacaaaacaa tacagctcat
    13441 tgaaatatag gaacattaaa attcagaaag atttcttttc ttgctaaaaa tctttcatcc
    13501 atttcaaact ggttttcatt tgtcctctcc tttttcagtt ctgctttttc tccataagct
    13561 gcacagttga tgtactcctt gcctttaccg tacttcttta caaatgtaaa atttacaact
    13621 tatacttctt ctccttctct ttcaaaactt gagtaaattg attctgctac taaatttgcg
    13681 ttaatattaa tcatttttta tccataattt ttctcctttt ttaatttaaa attcccatta
    13741 aaaaagcgac tggacttttt ccaatcgctg atacttctac tattttattt ttatttcggt
    13801 agaacttcta atccttatca tctatatcct cctttttaaa cacaaaaaag acggtagatt
    13861 ttttcttttt ccattgtctc ttataactta tatttaattt ttgaatagta tgcaaacatt
    13921 taaggaaaca actacttgct ttccaataaa aagtcaatca catttttgtg aataattcca
    13981 ttttgactaa aatccacttt atccatggat aagacaaatt taggataatt atctctaaca
    14041 aaatcataca caccaaactc tc
//
LOCUS       DARYYD010000048        13928 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.049, whole genome shotgun sequence.
ACCESSION   DARYYD010000048 DARYYD010000000
VERSION     DARYYD010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13928)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13928)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13928
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.049"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            102..1115
                     /gene="pfkA"
                     /locus_tag="TV188_001502"
     CDS             102..1115
                     /gene="pfkA"
                     /locus_tag="TV188_001502"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEL1534840.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGM
                     VDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSH
                     GRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIHKVVSTIKDDFENRGKNHHI
                     IVLAEGVMSGEAFAQQLKEAGDESDLRVTNLGHILRGGSPTARDRVIASWMGAHAVEL
                     LKEGKGGLAVGIHNEELVESPILGSAEDGALFSLTDEGNIVVNNPHKARLDYAALNRS
                     LAQ"
     gene            1177..2679
                     /gene="pyk"
                     /locus_tag="TV188_001503"
     CDS             1177..2679
                     /gene="pyk"
                     /locus_tag="TV188_001503"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018366040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEL1534841.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEQSAKKIAE
                     LIEAGANVFRFNFSHGDHKEQGDRMATVRLAEKLARQKVGFLLDTKGPEMRTELFADD
                     AKEYSYVTGERIRVATAQGIQSTRDMIALNVAGALDIYDEVEVGHTILIDDGKLGLKV
                     IEKDIAKREFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIA
                     ISFVRTAKDVEEVREICRETGNEHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPVEAVRTMATIDKNAQTLLNEYGRLDSSAFPRTNKTDVIASAVK
                     DATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAE
                     RPASTDDMFEVAERVALETGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK"
     gene            2808..3365
                     /gene="lepB"
                     /locus_tag="TV188_001504"
     CDS             2808..3365
                     /gene="lepB"
                     /locus_tag="TV188_001504"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEL1534842.1"
                     /translation="MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNK
                     GDLITIKKNIEPKYKDFVVYTVDKKDYVSRVVAVAGDRVTYMDDIFYLNNMVESQSYL
                     ESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
                     DVSQIKGLVTFRVLPLKDFGFVEVE"
     gene            3542..5353
                     /gene="glmS"
                     /locus_tag="TV188_001505"
     CDS             3542..5353
                     /gene="glmS"
                     /locus_tag="TV188_001505"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019804802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEL1534843.1"
                     /translation="MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNL
                     VKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVI
                     ENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
                     IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDS
                     ARVTDYAGNPIDRQSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQ
                     MMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLEHLTDTPVELGVASEWGYNMPL
                     LSKKPMFILLSQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREATYTMLLHAGP
                     EIAVASTKAYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKEL
                     IAEKVQTLLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLI
                     EDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIINKVHPFL
                     APIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE"
     gene            5537..5872
                     /locus_tag="TV188_001506"
     CDS             5537..5872
                     /locus_tag="TV188_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEL1534844.1"
                     /translation="MTLPNCLQCDSEYVYEDGHLLICPMCSFEWTRGEEEPEEEGLVV
                     LDSNGTRLADGDTVTIIKDLKVKGAPKDLKQGTRVKHIRLVEGDHNIDCKIDGFGAMK
                     LKSEFVKKI"
     gene            5979..6620
                     /locus_tag="TV188_001507"
     CDS             5979..6620
                     /locus_tag="TV188_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEL1534845.1"
                     /translation="MTYIMQVLPSLLDGALITLQVFFIVIVLSIPLGALLAFLMRVDF
                     KPLQWLLTLYIWVMRGTPLLLQLIFFYYVLPSVGVTFDRMPAAILAFTLNYAAYFAEI
                     FRGGIETIPNGQYEAAKVLKLSPVQTVRYVILPQVFKIVLPSVFNEVINLVKDSSLVY
                     VLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTILSKQVEKRFNYYQ"
     gene            6630..7259
                     /locus_tag="TV188_001508"
     CDS             6630..7259
                     /locus_tag="TV188_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEL1534846.1"
                     /translation="MLELNNISKRFGHKQIFDGFHLTVEDGEVLSLVGPSGGGKTTLL
                     RMLAGLEPIDSGNISYNGESVPIDHLEKRSLLGFVFQDFQLFPHLTVLDNLILSPTIT
                     MAMPRPDAKQKAMELLERLGLKEHAAAYPYALSGGQKQRVALARAMMIDPQIVGYDEP
                     TSALDSELRQEVEKLILQNREMGITQIVVTHDLQFAQTISDRIIKINPK"
     gene            7276..8112
                     /locus_tag="TV188_001509"
     CDS             7276..8112
                     /locus_tag="TV188_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1534847.1"
                     /translation="MTLKKTLLVALFAATATLLVACGASNKQTSSDAWDSYKQKKTIT
                     LGFDNTFVPMGYKDESGKNTGFDIELAKAVFDQYGINVKYQAINWDLKETELNNGKID
                     LIWNGYSVTKERQAKVAFTEPYMKNEQVLVTQKSSQISSFADMKNKTLGAQSGSSGYD
                     AFTSHPKVLKDLVKGNDATQYETFTQAFIDLKNKRIDGLLIDRVYANYYLQQEGELDR
                     YNIIASEFEGEDFAVGVRKADKTLQKKITQALKSLYQDGTFQKISKKWFGEDVATVQL
                     KS"
     gene            complement(8208..9446)
                     /locus_tag="TV188_001510"
     CDS             complement(8208..9446)
                     /locus_tag="TV188_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEL1534848.1"
                     /translation="MPNNPVENLRLAKRGPIVSIVTYLALSITKLLAGYLLNASSLIA
                     DGFNNLSDIVGNVTLLIGLHLASQPADANHRFGHWKIEDLSSLITSFIMFIVGFQVLL
                     QTIQQMISGKQSAIDPLGAIVGIASALVMLGVYAFNKALSKKVRSSALVAASKDNLSD
                     AVTSIGTSIAIIAASLKLPIIDRLAALIITFFILKTAFDIFMASAFSLSDGFDSTQLK
                     AYEKAILKIPKIIAVKSQRGRTYGSNVYLDIVLEMHPDLSVYESHAITEQVEQLLSEQ
                     FAVYDIDIHVEPAKLPKDDNCEYVYKKLYKNEKIMLSQIPDYQELIAKTFTFIDRDGQ
                     AYNAKQFLEQQRSSSNQLEAFCMQSISHNTKLVTYQLQGNQHTSIWRRHEAWHLIYHQ
                     ITPITNSIAIKKHYHIKRIS"
     gene            complement(9549..10883)
                     /locus_tag="TV188_001511"
     CDS             complement(9549..10883)
                     /locus_tag="TV188_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEL1534849.1"
                     /translation="MIAAAKWIDDLVWGAPLLLLLLGTGIYLTSRLSLLQVIKLPKAF
                     RLIFAKNEGQGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGM
                     ATKYSEGVLAIKYRTKDANGQISGGPMYYILNGMGQKWRPLANLFAVSGILVALFGIG
                     TFAQVNAITSSLHHSLGISSPLISVLLAAVVAMIIFGGIQAIAKVAETVVPFMAIFYI
                     GASLTVIAVHYTKLLPMLVLIFKSAITPTAAIGGFAGSLVKDAIQKGIARGVFSNESG
                     LGSAPIAAAAAKTKEPVEQGLISMTGTFIDTIIICTLTGLAILVTGQWTSALEGAPLT
                     QSAFASIFGHMGTYALTLSLVLFAFTTILGWSYYGERCFIFLFGTTHLSYFRLIFVIM
                     VGLGGFLKLELIWILADIVNGLMALPNLIALLALSPVVIFETRAYFKRQSTK"
     regulatory      complement(11012..11098)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            11363..13654
                     /gene="pcrA"
                     /locus_tag="TV188_001512"
     CDS             11363..13654
                     /gene="pcrA"
                     /locus_tag="TV188_001512"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEL1534850.1"
                     /translation="MNPLLDGMNDKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKYVNPWNILAITFTNKAAREMRERALALSPATKDTLIATFHSMCVRILRREADHI
                     GYNRNFTIVDPGEQRTLMKRIVKALNLDPKKWSERSILATISNAKNDLLDERAYELGA
                     SDLYSQTVARCYKAYQEELRRSEAMDFDDLIMMTLRLFDQNPDVLAYYQQRYQYIHVD
                     EYQDTNHAQYQLVTLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDARVVL
                     LEENYRSTKKILQAANEVIQHNRHRRPKKLWTQNADGEQIVYYRANDERDEAVFVAST
                     ISNMCLELGKSFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDVIA
                     YLTVVANPSDNLSFERIVNEPKRGVGPGTLDKLRQFAYGQGQSLLEAASSLEQSPLKG
                     KAAQAMLALASLLSDLRADLDQLSITALAEALLEKTGYLDMLRVQNTLESQARIENIE
                     EFLSVTKSFDDLSAQQQEHEAGIDRLGRFLNDLALIADSDDGNAETAEVTLMTLHAAK
                     GLEFPVVFLIGMEEGVFPLARAAEDQDELEEERRLAYVGITRAEECLFLTNANTRTLF
                     GKSSYNRPTRFLKEMSENLLSFQGLARPAHASFGVTFSQQGQRQFGTGMSLSEAIQSR
                     KSMAQPARAASTSTPLPFGPNAATSKQAVDWQIGDIAHHKKWGAGTVLEVKGSGKTME
                     LTISFPDVGLKKLLASVAPIEKK"
BASE COUNT         4068 a         2601 c         3254 g         4005 t
ORIGIN      
        1 gttgaaaacg gtttttcgat aaaaatagcg aattagtgaa gtaatttgca aacgaatgtg
       61 ctataataaa aacgttaaat taattaaagg agtaccaaaa aatgaaacgt attgctgttt
      121 taaccagtgg tggtgacgcc cctggtatga atgctgctat tcgtgcagtt gttcgtaaag
      181 caatttcaga aggaatggaa gtctatggta ttaaccgcgg ctatgctggt atggttgatg
      241 gtgatatctt tccactaggc tcaaaagagg ttggtgataa gatttctcgc ggcgggacct
      301 tcctttattc agctcgctac ccagagtttg ctcagcttga ggggcaattg gctggtattg
      361 agcagctaaa aaagcatggc attgaagggg tagttgtcat tggtggtgat ggttcttacc
      421 atggtgcgat gcgcttgact gagcatggct tccctgcagt aggtatccca gggacgattg
      481 ataacgatat tgctggaaca gactatacta tcggatttga cactgcggtc aatactgcgg
      541 tagaggctat tgataagctt cgcgatacct catcaagtca tggacggacc tttgttgttg
      601 aagtgatggg acgcaatgca ggtgatatcg cactttgggc aggtattgca agtggagcag
      661 atcaaatcat cgttcctgaa gaggaatttg acattcataa agtggtctca acaattaaag
      721 acgattttga aaatagagga aaaaatcacc atattatcgt tttagctgag ggtgttatga
      781 gtggcgaggc ctttgcgcag cagctaaaag aagctggaga tgaaagtgac cttcgtgtga
      841 caaaccttgg tcatatcctt cgcggtggct ctccaactgc gcgtgatcgt gtgattgcgt
      901 catggatggg agcgcacgct gttgagttgc tcaaggaagg caaaggtggc ttggctgttg
      961 gtattcataa tgaagagctt gttgaaagtc cgattcttgg aagtgcagag gacggtgcct
     1021 tgttcagcct tactgatgag ggtaacattg ttgttaataa cccgcacaag gctcgcttag
     1081 actatgctgc tttgaaccgt tcattagcac aataggataa gtaagatctg gtaatctttg
     1141 ttaatcaact aaaaaataag ggagtttcat aataaaatga ataaacgtgt aaaaattgtt
     1201 gcaacacttg gtcctgcggt tgaaattcgc ggtggtaaaa aatatggtga ggacggctat
     1261 tgggctggtc agttggacgt tgaacaatca gctaaaaaga tcgctgaatt gattgaagca
     1321 ggtgctaatg ttttccgctt taacttctca catggtgacc acaaagagca gggtgaccgt
     1381 atggctactg ttcgtcttgc tgaaaagctg gcacgtcaaa aggttggttt ccttttggat
     1441 acaaaaggac cagaaatgcg tacagaattg tttgctgacg atgccaaaga atatagctat
     1501 gtgactggtg agcgtattcg tgttgcgaca gcacaaggca ttcaatcaac tcgtgatatg
     1561 attgccttga atgtagctgg tgctcttgat atttatgatg aggttgaggt tggccacact
     1621 attcttattg acgatggaaa gcttggctta aaggttatcg agaaggacat tgcaaagcgt
     1681 gagttcatcg ttgaggttga aaatgatggc atcattgcaa agcaaaaggg tgttaatatc
     1741 cctaatacca agattccttt cccagcctta gcagaacgtg ataatgctga tattcgtttt
     1801 ggtcttgagc aaggtcttaa ctttattgct atttcatttg ttcgtactgc caaggacgtt
     1861 gaagaggttc gtgagatttg tcgtgaaaca ggcaatgagc atgttcaatt atttgctaaa
     1921 atcgaaaacc aacaaggtat tgataacctt gatgaaatca tcgaagctgc agatggtatc
     1981 atgattgctc gtggtgatat ggggattgag gtgccatttg aaatggttcc agtcttccaa
     2041 aaaatgatta tcaccaaggt aaatgcagca ggtaaagcag tcatcaccgc aactaacatg
     2101 cttgaaacaa tgactgaaaa accacgtgca actcgttcag aggtatctga cgttttcaac
     2161 gcggttattg acggtacaga tgcgacaatg ctttctggtg aatcagcaaa tggtaaatac
     2221 cctgttgaag cagttcgtac aatggctaca attgataaaa atgcacaaac tcttcttaat
     2281 gagtatggtc gtttagattc atctgccttc ccacgtacca ataaaactga cgtgattgct
     2341 tcagctgtta aagatgcaac acactcaatg gatatcaagc ttgttgtgac catcactgaa
     2401 acaggaaaca cagctcgtgc catttctaag ttccgtcctg atgctgacat cttggctgtg
     2461 acctttgatg aaaaggttca acgtgccttg atgattaact ggggtgtgat tccagtgctt
     2521 gctgaaagac cagcatcaac agatgatatg tttgaggtag cagagcgtgt agctcttgag
     2581 actggtttgg tgcaatcagg agataatatc gttattgttg caggtgtgcc agttggtaca
     2641 ggtggtacaa atacaatgcg tgttcgcact gtaaaataat agctttccat aagctttagc
     2701 tattttgctc tatcagataa tttaaggcaa acaatgatac ttaaaaattg tttgcttttt
     2761 ttattagtca tatcatgtta taatgagact atagactagg agttattatg gtaaagcgag
     2821 attttataag aaatatattg ttgttattga ttcttattgt gggagctgtc cttcttagaa
     2881 tatttgtttt ttcgacctat cgagtcacgt cagaggcttc aaatgcctat ttgaataagg
     2941 gcgatttaat caccattaag aaaaatattg agcctaaata taaggatttt gtggtttata
     3001 cggttgacaa aaaggattat gtgagccggg ttgtagcagt agcaggtgat cgtgttacct
     3061 atatggacga tattttttac ctgaacaata tggttgaatc ccaatcctac cttgagagta
     3121 tgaaggcaaa gtatctcaat catgccccta ttggtacgct ttatacggag gattttacga
     3181 tttcgacggt tacttctgga aaatacgata gcattcccaa ggggaaatac cttttgctaa
     3241 atgataacag aaaaaaccat catgatagcc gtcagtttgg cttaattgac gtgtcacaaa
     3301 ttaagggatt agtaacattt agagtgcttc ctttgaaaga ctttggattt gtagaggtag
     3361 agtagcttta aggctgctct attttgtttc tcaaaatatg actataccaa ttttcttgtt
     3421 gacaagattt ttctgaagtt atatactcta aatataacgt tttagtcggt ttatatctga
     3481 ctataccaat tatattgatc attaaagaaa gtagtaagct agcttactga ggtgttaagt
     3541 tatgtgtgga attgttggag ttgtaggtag tcgtaatgcg actgacatct tgatgcaggg
     3601 attggaaaaa ttagagtatc gtggttatga ttcagctggt atttttgtgt cagatggcag
     3661 gacgtccaat ttggtaaaat ctgttggacg cattgcagat ttacgctcta agattggcat
     3721 tgatgttgtt ggaacgaccg gtattggtca tacacgttgg gcaacgcatg gtcaagcaac
     3781 agaggaaaat gctcaccctc atacctctca gacaggtcgc tttgttcttg ttcataatgg
     3841 tgtgattgaa aattacctcc agatgaagga gcagtacctt gctggacaca cgtttaaagg
     3901 acaaacagac accgaaattg cagttcattt gattggagca tttgttgaag aaggctgttc
     3961 agtcttagag gcttttaaaa aggctttatc aatcattgaa ggctcctatg cctttgcttt
     4021 gattgataca gaggatatgg atacgatcta tgtcgctaag aataaatccc cattgctgat
     4081 tggccttggt gagggctata acatggtttg ttcagacgct atggccatga ttcgtgaaac
     4141 cagcgaattt atggaaatcc atgacaagga gctggttatc ctgacaaagg attcagcaag
     4201 ggtgacagat tatgctggca atccgattga tcgtcagtca tatacagcag agcttgatct
     4261 ttcagatatt ggcaagggga cctatccatt ttatatgcta aaggaaattg acgagcagcc
     4321 aacagtgatg cgtcgcttga tttcaaccta tgcagacgcc aagggacaga tgatgattga
     4381 tccagctatc ataaggtctg tccaagaggc tgatcgtatc tatattcttg cagctgggac
     4441 ctcttatcat gctggctttg cttctaagtc aatgctggag catttgactg atacacctgt
     4501 tgaattaggg gttgcttctg agtggggcta caatatgccg ctattgagca aaaagccaat
     4561 gtttatcctc ttgagccagt ccggtgagac agcagatagc cgtcaggttt tggtcaaggc
     4621 aaatgagatg gggattccaa gcctaacagt gacaaatgtt cctggctcaa ccctatcacg
     4681 tgaagcaacc tacactatgc tgctccatgc aggtccagaa attgcagttg catcaactaa
     4741 agcctacaca gcacaggtcg ctgcacttgc ctttctagct aaggcagttg gtgaggctaa
     4801 tggcaagaag gaagctatta gctttgattt ggttcatgaa ttgtcattgg tcgctcagtc
     4861 tattgaggcc accttatctg acaaggagct gattgctgag aaggtgcaga ccttattggc
     4921 aacaacacgc aatgcgtttt acattggtcg tggcaatgat tattatgttg ctatggaggc
     4981 tgcactaaaa ttaaaagaaa tttcatacat tcagtgtgaa gggtttgcag ctggtgagct
     5041 aaagcatggg actatttcac tgattgagga tggcacacct gttattggac ttatttcttc
     5101 aagtgagctg gttgctgcac atacacgtgg caatatccaa gaggtggctg cacgtggcgc
     5161 tcatgtgttg acagttgttg aggagggctt agagcgtgag ggagatgaca ttattattaa
     5221 taaggtgcac ccattcttag cgccgattgc tatggttatt ccgactcaat taattgctta
     5281 ctatgcttcc ttgcagcgtg gtttagatgt agataagcct cgtaatttag ccaaggctgt
     5341 tacagttgag taatagttgc ctgcttaaaa tgaggcagca gggtcctgaa gcctatttga
     5401 aacgagcttg acatgatgtt atgtcaggct cgttttttag tgcttgcctg gtcttatgat
     5461 aacgtattca tcttgtcaaa taagcatttc tgaagtaaaa tattaacgtt aagactaaga
     5521 agcttaggag agtaagatga cgttaccaaa ttgtttacaa tgcgattcag aatatgttta
     5581 tgaggacggg catttgctca tttgtccgat gtgttccttt gaatggacac gtggtgagga
     5641 ggagcctgag gaggaggggc ttgtcgtttt agatagtaat ggaactagat tagctgatgg
     5701 agacactgtt acgatcatta aggacctgaa ggtcaaggga gcgccgaagg atctcaagca
     5761 gggaactcgt gttaagcata ttcgtcttgt tgaaggtgat cacaatattg attgtaagat
     5821 tgatggcttt ggtgcaatga agctaaaatc agaattcgtc aagaagattt aataacaata
     5881 agcaaccaga tgactggttg tatttttata gaaaagtact tttcaatcca tcagaaaatt
     5941 tggtataatg gataaactat ttatatctag gagacaacat gacgtatatt atgcaggttt
     6001 tacccagctt gctggatggt gccttaatca ctttacaggt tttctttatt gtaattgtat
     6061 tatccattcc cttaggggct cttttagctt ttttgatgag ggttgacttt aagcccttgc
     6121 agtggctatt gacgctctat atttgggtca tgaggggaac acccttattg ttacagctca
     6181 tcttttttta ttatgttttg ccaagtgtgg gtgttacctt tgatcgtatg ccggcagcga
     6241 ttttggcttt taccttaaac tatgctgctt attttgccga gatttttcgt ggcgggatag
     6301 agactattcc aaatgggcaa tatgaggctg caaaggtgct gaagcttagt ccggtacaaa
     6361 ctgttcgcta tgttatcttg cctcaggtgt tcaagattgt tttaccaagt gttttcaatg
     6421 aggtgattaa cttagttaag gattcttcct tggtatatgt gttaggagta ggggatttgc
     6481 tattagcaag caagactgcg gcaaatagag atgcaacctt agcaccgatg tttattgcag
     6541 gtttgattta tttgctctta attggtttgg tcaccatttt atcgaagcag gttgaaaaaa
     6601 gatttaatta ttatcagtaa gggggtcata tgttagaact gaacaatatt tcaaagcgat
     6661 ttggtcacaa gcagatcttt gatggctttc atttgaccgt tgaagatggt gaggttttat
     6721 ctttggtagg gccatctggt ggtggcaaga ctactctgct ccgaatgctg gctggcttag
     6781 agcctattga ttcgggaaat attagctata atggcgagtc tgttcctatt gatcatttag
     6841 aaaaaagaag cctgcttggt tttgtttttc aggatttcca attgtttcca catttgacgg
     6901 tgctggataa tctcatcttg tctcctacca ttaccatggc tatgccaagg cctgatgcaa
     6961 agcaaaaggc tatggagctg ctggagcgcc taggtctcaa agagcatgca gctgcttatc
     7021 cttatgcgct atctggtggg caaaagcaaa gagttgcctt ggctagagcg atgatgattg
     7081 acccacagat tgtaggctat gatgagccga caagtgcctt agactctgaa ttacgtcagg
     7141 aggttgagaa attgattttg caaaatcgtg agatgggcat tacccagatt gttgtcaccc
     7201 atgatttgca gtttgctcag accatttctg atcgtatcat caagatcaat cctaaataga
     7261 agaagaggta gtgctatgac gttaaaaaag acccttctag tagccctatt tgctgctaca
     7321 gctacgcttt tagtagcttg tggcgctagt aataaacaga ctagctcaga tgcttgggat
     7381 tcctacaagc agaaaaagac gattacgctt ggctttgata atacttttgt gccaatgggc
     7441 tataaggacg agtcaggaaa aaataccggc tttgatattg agctagcaaa ggctgttttt
     7501 gaccaatatg gtatcaatgt taagtatcaa gccattaact gggatctcaa agaaactgag
     7561 ttgaacaatg gtaaaattga cctgatttgg aatggctatt ctgtgacaaa agagcgccaa
     7621 gctaaggtgg cctttacaga gccttatatg aaaaatgagc aagtcttagt gacgcaaaaa
     7681 tcatcgcaaa taagctcatt tgctgatatg aaaaataaga ccttaggtgc ccagtctggc
     7741 tcatctggct atgatgcctt tacgagtcat cctaaggtgc taaaggatct tgtcaaggga
     7801 aatgacgcta cccaatatga aacctttaca caagccttta tcgatttaaa aaacaagcgt
     7861 attgatggcc ttttgattga tagggtttat gccaattatt accttcagca agaaggtgag
     7921 ctagaccgct ataacattat cgcgagtgag tttgaaggtg aggattttgc agttggtgtc
     7981 cgaaaagcgg ataaaaccct acaaaaaaag attacacaag ccttaaaatc gctttatcag
     8041 gacggtacct tccaaaaaat ctctaaaaaa tggtttggtg aagatgtcgc aacagttcag
     8101 ttgaaatcat aagacgcaag caagacctaa tcagctcaga ggggttgaga ctagatacat
     8161 ttaaaagact taccttctaa aggcaagtct ttttatacgg cttattatta gctgatacgc
     8221 ttgatatgat agtgtttttt aattgctatg gagtttgtta ttggtgtgat ttgatgatat
     8281 atcaggtgcc aagcttcgtg tcgtctccag atactggtat gctgattgcc ctgtagctga
     8341 taggtgacta gcttggtgtt gtggctgatg gattgcatac aaaaggcttc aagctgattg
     8401 gaagaagaac gctgctgctc taaaaattgc ttggcattgt aagcttgtcc atcgcgatca
     8461 ataaaggtaa aggtcttggc aatgagctct tgataatctg ggatttgact tagcatgatt
     8521 ttctcgtttt tgtagagctt tttgtaaaca tattcacagt tgtcatcttt aggaagcttt
     8581 gcaggctcaa catgaatatc aatatcataa acagcaaatt gctcactcaa gagctgttcg
     8641 acctgctcgg ttatggcgtg actttcataa acagaaaggt cagggtgcat ctcaaggaca
     8701 atatctaaat agacattgct tccgtaagtg cggccgcgct gtgatttgac agcaatgatt
     8761 ttgggaattt tcaatatggc cttttcatat gctttgagct gcgtgctgtc aaagccatct
     8821 gataagctaa aggcgcttgc cataaaaata tcaaaggctg tttttagaat gaaaaaggta
     8881 atgataaggg cagccagcct atcaataata ggtagcttta aggaagcggc gataatagca
     8941 atagaggttc caatagaggt cacagcatca gaaagattat ctttagaggc tgcaaccaag
     9001 gcactggatc ttaccttttt tgataacgct ttattaaaag catatactcc aagcatcaca
     9061 agggctgaag cgatcccaac aatagcacct aatggatcga tagcagactg cttaccacta
     9121 atcatctgtt gaatagtttg caggagaacc tgaaagccaa caatgaacat gataaaggag
     9181 gttattaagc ttgaaaggtc ttcgattttc cagtggccaa agcggtgatt ggcgtctgct
     9241 ggctggctgg ccagatgaag tccgatgagc agagtgacat taccaacgat atcagacagg
     9301 ttgttgaagc catcggcaat caaggagctg gcatttaaaa gatagccagc aagaagcttt
     9361 gtgatgctaa gggccaaata ggtaacaatg ctaacaatgg gccctctttt tgctaaccga
     9421 aggttttcta ctggattgtt tggcataaaa actcctttgt aactgatgct ttcattatat
     9481 cataaaagct aagacaagct aaaagcctag agctatccta aatagggtat tccaggcttt
     9541 tcgatagctt atttggtgct ttggcgctta aaatatgccc ttgtctcaaa aatgacaaca
     9601 ggagataagg ctagtagggc gataagattt ggcagagcca tcaggccatt gacaatatct
     9661 gccagtatcc aaatcaactc cagcttaaga aagccaccaa gtcctaccat gataacaaag
     9721 atcaggcgaa aatagctgag gtgtgtcgtg ccaaataaaa agataaagca gcgctcacca
     9781 taatagctcc agccgagaat agtcgtaaaa gcaaaaagaa caagcgacag ggtcaaggca
     9841 taggtgccca tatgcccaaa gatagaagca aaggcagact gtgttaaggg tgctccctct
     9901 agtgcgctag tccactgacc agttaccaaa atggccagac cagtcagagt gcagatgatg
     9961 atcgtgtcaa taaaggttcc ggtcatagaa atcaggccct gttctactgg ctccttggtt
    10021 ttagcggcag cagcagcgat cggagcagag cctagtcctg attcgttaga aaaaacccca
    10081 cgtgcaatac ccttttgaat ggcgtcctta accaagcttc cggcaaagcc ccctatagct
    10141 gctgtagggg taatagcgga cttaaagata aggacaagca taggaagaag cttagtatag
    10201 tgaacagcaa taaccgttaa gcttgctcca atataaaaga tagccatgaa aggaacgact
    10261 gtttcagcca ccttggcaat agcttgaatg cctccaaaaa taatcatggc cacaacagca
    10321 gctagcaaga cactgattaa tggcgaagag atcccaaggc tatggtgtag ggatgaggta
    10381 atcgcattga cctgagcaaa tgtcccgatt ccaaacaaag ccactaaaat accagagaca
    10441 gcaaataagt tggctagagg cctccatttt tgccccatac catttaaaat gtagtacata
    10501 ggtccgcctg aaatctgacc attagcgtcc ttagtacggt atttaatggc taaaacgccc
    10561 tcggaatatt tggttgccat accaaagaag gcagcaaccc acatccaaaa aagtgcccca
    10621 ggtccaccag actttatagc ggttgcgaca ccaacaatat taccagtacc aactgtagca
    10681 gctagggctg ttgctagagc agcaaatgat gaaatatctc cttgcccctc attcttagca
    10741 aaaatgagcc taaaggcctt aggcaacttg atgacttgga gaaggctaag tctgctggtg
    10801 aggtaaatgc cagtaccaag cagcagtagc aacaagggtg ctccccaaac caaatcgtct
    10861 atccattttg cagcagctat catgcttaat tcctcaactc tcttaaccaa tgctgccaaa
    10921 agaaaaagcc acccctgcgg atagcctctg aagcatatga caaaacagca agcacaaaaa
    10981 atgctaagga agcatgatca tacggcttga tattttatct tctgtccttt tgcctgagag
    11041 attgagcagt cttgccttgc cccttcggcg cctaataggt ctctccagaa gcccgtccgt
    11101 caagcagtcc cgtccaacac ctgaacacct gagagtataa ctccttcggc gaaatccatt
    11161 cttctcctgc atgacatcat tcggtttatt aaattatgtc tatgataccc aaaaagccta
    11221 gtgatgtcaa caagcaattt aactgatggc taactccttg tttttatggt aacatcattg
    11281 tcctcttttt tctttttgac tgaaacatga tataatcgta aggttaataa aagtcactta
    11341 ttagacgata tgaggagaaa gcatgaatcc tttattagat ggaatgaatg ataaacaagc
    11401 agaggcagtt caaacgactg agggcccctt gttaattatg gctggtgccg gttctgggaa
    11461 aacgagggta ttaacccacc gcattgccta cttgattgat gaaaagtatg ttaatccctg
    11521 gaatattttg gcgattacct ttactaataa ggctgcgcgt gagatgcgag aaagggcatt
    11581 ggccttaagc ccagccacca aggatacctt gattgcgacc tttcactcaa tgtgtgttcg
    11641 tattttacgc cgtgaggcag atcatattgg ctacaatcgg aatttcacga ttgttgatcc
    11701 aggagaacag cggaccttaa tgaagagaat agtaaaagct ctaaatctgg atcctaagaa
    11761 atggagcgag cggtcgattt tagccaccat ttcaaatgct aaaaatgatc tcttagatga
    11821 aagagcctat gagctaggag cctctgattt gtatagccag acagttgccc gctgctacaa
    11881 ggcctatcag gaggagctca gacgaagtga ggctatggat tttgatgatt tgattatgat
    11941 gaccttacgc ctatttgatc aaaatcctga cgttctagcc tattatcagc agcgttatca
    12001 atatatacat gtcgatgaat accaagacac aaaccacgct caatatcagc tagtgactct
    12061 tttagcctca cgctttaaaa atatttgtgt tgtcggtgat gcagaccagt ccatttatgg
    12121 ctggcgtggt gctgatatgc aaaatatttt agattttgaa aaggattacc ctgatgcaag
    12181 ggtggttttg ctggaagaaa attatcgctc caccaagaaa atccttcagg cagctaacga
    12241 ggtgattcag cataatcgtc atcgtcgtcc gaaaaaattg tggactcaaa acgcagacgg
    12301 tgagcagatt gtttattata gggcaaatga tgagcgtgac gaggctgttt ttgttgcctc
    12361 aaccatcagc aatatgtgtc tagagctagg aaagagcttt aaagactttg ctgttttata
    12421 tcgtaccaat gctcagtccc gtacgattga agaagccttg ttaaaatcaa atattcccta
    12481 cacgatggtc ggaggaacca aattctacag cagaaaggaa attcgtgatg tgattgccta
    12541 tttgactgtg gttgctaatc cgtcagataa tctctccttt gaacgaattg tgaatgagcc
    12601 taaacgaggg gtagggccag gaaccctaga taagctccgc caatttgctt atgggcaagg
    12661 acagtcattg ttagaggccg cttcaagcct tgagcaatca ccgctaaaag gaaaggctgc
    12721 ccaagccatg ctggccttag cgagtctctt aagtgatttg agagctgatt tagaccagct
    12781 gagcattaca gccctggccg aggccttgct ggagaaaacc ggctatctgg atatgctgcg
    12841 cgtccaaaat accttagaaa gtcaagctag gattgaaaat attgaagaat tcctgtctgt
    12901 taccaaaagc tttgatgacc tatcagcaca gcagcaggag catgaagcag gtattgatcg
    12961 cttaggaaga tttctcaatg accttgcttt gattgctgat agtgatgatg gcaatgcaga
    13021 aaccgctgag gtaactttga tgactctgca tgcagctaag gggctagaat ttcctgttgt
    13081 ttttctcata ggtatggagg agggagtctt tcctttagcc cgagcagccg aggatcaaga
    13141 tgagctagaa gaagaaaggc gactagccta tgttggcatt accagagccg aggaatgctt
    13201 gtttttaacg aatgccaata cacgtaccct atttggtaaa agcagctata atcgcccaac
    13261 aaggttttta aaagagatgt cagagaacct tttaagcttc caaggcttgg caagacctgc
    13321 tcatgcttcc tttggtgtga cattttcgca gcagggtcaa cgacaatttg gcacaggaat
    13381 gagtctatca gaggctatcc agtccagaaa atcaatggca cagcctgcca gagcagcctc
    13441 aacatctaca ccgctgccct ttggaccgaa tgcagctact tcaaagcaag ccgttgattg
    13501 gcagattggt gatattgccc atcataaaaa atggggtgct ggaacggttt tagaggtcaa
    13561 gggatctggt aagaccatgg aattaaccat tagttttcct gatgtcggat taaaaaaact
    13621 ccttgccagc gttgctccta ttgaaaaaaa ataaaaggta cagcttatgg gcaatttgca
    13681 tagtcacttg gataagggct ttgcaattgc ggtttagttc tgcgatttaa gaaaagaagt
    13741 aagcaaggat tttatcagtt aaccacatac caagcttttg atggccttga tgccggagag
    13801 agcttggtat ttttttattt ttaaaaaaat cacaaaaaat gatttattct gagcataatc
    13861 cttgcaaatt aaaatgagaa gcgtataatg gcaatataaa ttaaataaca agtggtcact
    13921 tttgttaa
//
LOCUS       DARYYD010000049        13214 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.050, whole genome shotgun sequence.
ACCESSION   DARYYD010000049 DARYYD010000000
VERSION     DARYYD010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13214
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.050"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(241..489)
                     /locus_tag="TV188_001513"
     CDS             complement(241..489)
                     /locus_tag="TV188_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEL1534851.1"
                     /translation="MEVKTLANIKSAIKRAELNVKANEKNSAQKSAMRTAIKAFEANP
                     SEELFRAASSSIDKAQSKGLIHKNKASRDKARLAAKLS"
     gene            complement(543..1463)
                     /locus_tag="TV188_001514"
     CDS             complement(543..1463)
                     /locus_tag="TV188_001514"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEL1534852.1"
                     /translation="MSNEFITFEKISRKSWKQLHQKSKPLLTQEELTSITSLNDNIDI
                     NDVVEVYLPLIHLIQVYKIAQENLSFSKSLFLKKDIQQRPFIIGISGSVAVGKSTTSR
                     LLQLLLARTHKTSTVELVTTDGFLYPNSTLIKNNMLNRKGFPESYNMELLLNFLDTVK
                     GGQTASAPVYSHEIYDIVPDQQQTFTNPDFLIIEGINVFQNQQNNRLYMSDYFDFSIY
                     IDADSHHIEQWYLERFLSLLELAKHDPANYYTRYTSLPQNEAIAFAKKVWKTINLENL
                     EKFIEPTRNRAELILHKAADHKIDEIYLKK"
     gene            1697..2326
                     /locus_tag="TV188_001515"
     CDS             1697..2326
                     /locus_tag="TV188_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1534853.1"
                     /translation="MKKHRKKIGKHMTKMYYDENPDSAHDIHQLTVNLLGQSFTFLTD
                     SGVFSKRMVDFGSQVLLNTLDFQEGDRLLDLGCGYGPLGLSLAKAQGVEATLVDINHR
                     AVGLAKQNAESNQVEATIFQSNLYDGVTGTFEHIISNPPIRAGKKVVHEIIEKSIDFL
                     TKGGDLTVVIQKKQGAPSAKDKMEAVFGNVTILKREKGYYILRSIKERN"
     gene            2425..3702
                     /locus_tag="TV188_001516"
     CDS             2425..3702
                     /locus_tag="TV188_001516"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEL1534854.1"
                     /translation="MRAVDLIQKKRDGKELSTEEIQWLINGYANGTVPDYQMSAFAMA
                     IYFKGMSTRETRDLTMSMVETGEQIDLSAIAGIKTDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTLDKLESIKGFQIGRTQEEFIKQVQEIGLSVIGQSDKLVKA
                     DKLLYALRDVTATVDIVPLIASSVMSKKIAAGADSILLDVTVGDGAFMKTIEDAEKLS
                     RLMVDLGKEVGRQTVAVITDMSQPLGRAIGNRLEVLEAIDIMKGKGRKDITHFICELA
                     QIMLELAGAQHSLEDIHHHLVGGAALKKLEEMVVYQGGDLEDLYRPSQAAVQTEVFAS
                     EDGYITALPALEFGLFAMRLGAGRAVKTDSLDYETGIVFDKKVGDAVAKGERIAVVFS
                     QEALDEKMLTEFEKNVKIGAEHLEANEIIKIIS"
     gene            3716..4378
                     /gene="deoC"
                     /locus_tag="TV188_001517"
     CDS             3716..4378
                     /gene="deoC"
                     /locus_tag="TV188_001517"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEL1534855.1"
                     /translation="MNINKYIDHTLLKADSVQSQLDQLIEEAKAYDFASVCVNPCWVA
                     YAAKALKGTDVKVCTVVGFPLGATTSATKAFETKDAIENGADEIDMVINIGLLKQGDY
                     QAVEDDMRAVVEASGDKLVKVIIEACLLTDDEKVKACQLAVNAGVDFVKTSTGFSTGG
                     ATVSDVKLMRQTVGPDIGVKAAGGARSLEDALAFVEAGATRIGTSAGVTIMKGEVANG
                     GY"
     gene            4365..4754
                     /locus_tag="TV188_001518"
     CDS             4365..4754
                     /locus_tag="TV188_001518"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEL1534856.1"
                     /translation="MEATDLVSLAIEASKRAYVPYSHFPIGAALKTKDGTIYTGNNIE
                     NASFGLTNCGERTAIFKAVSEGHQQLLEIAIYGETDEPISPCGACRQVMAEFFEATAP
                     VTLIAKDGRTMRTTVGELLPYSFTDLS"
     gene            4845..5897
                     /locus_tag="TV188_001519"
     CDS             4845..5897
                     /locus_tag="TV188_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003058857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEL1534857.1"
                     /translation="MNKKFIGVGLASVALLGLVGCGNRNASKGSGDAKTDLKVAVVTD
                     TGGVDDKSFNQSAWEGLQAWGKDNGLTKGSGFDYFQSTNESEYATNIDTAVSSGYEVV
                     YGIGFALKDAISKAADDNNKVQFVIIDDVIEGKDNVASVTFADNEAAYLAGIAAAMTT
                     KTKTVGFVGGMEGTVVTRFEKGFEAGVKSVDDSIKIKVDYAGSFGDAAKGKTIAAAQY
                     AAGADVIYQVAGGTGAGVFNEARTINEKRDEADKVWVIGVDRDQNEEGKYTSKDGKSS
                     NFVLASTIKGVGKAVQLINKQAADKKFPAGKTTVYGLKDGGVEIATTNLSKDVIKAIE
                     EAKEKIKSGDVKVPEK"
     gene            6024..7556
                     /locus_tag="TV188_001520"
     CDS             6024..7556
                     /locus_tag="TV188_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534858.1"
                     /translation="MAQHVIEMKEITKKFGDFVANDHINLNVRKGEIHALLGENGAGK
                     STLMNMLAGLLEPTSGNIVINGQPVVIDSPSKSARLGIGMVHQHFMLVEAFTVAENII
                     LGNEVVKNGCLDLKKASKDIKELSEKYGLAVDPTAKIADISVGAQQRVEILKTLYRGA
                     DILIFDEPTAVLTPAEIQELMEIMRNLVKEGKSIILITHKLDEIRAVADRVTVIRRGK
                     SIQTVDVAGATSQDLAEMMVGRSVSFTTAKKAAEPKGVVLSIKNLEVDENRGIPAVKG
                     LSLDVRAGEIVGIAGIDGNGQSGLIQAITGLRKTRSGSITIKGQEVVHLSSRKITELS
                     VGHVPEDRHRDGLVLDLSLAENTALQTYYKEPLSKNGILNYNTINDYARRLMKEFDVR
                     GANELVPARGFSGGNQQKAIIAREVDRNPDLLIVSQPTRGLDVGAIEYIHKRLIEERD
                     KGKAILVVSFELDEILNLSDRIAVIHDGKIQGIVLPQDTNKQELGILMAGGSIDKEES
                     HV"
     gene            7549..8613
                     /locus_tag="TV188_001521"
     CDS             7549..8613
                     /locus_tag="TV188_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1534859.1"
                     /translation="MSKNAQKIAVPMISILLGFLLGAIVMFIFGYDPIWGYEGLFQVA
                     FGSIKNIGEIFRAMGPLILIALGFTVASRAGFFNVGLSGQALAGWIAAGWFALVNPNM
                     PRPLLILMTVLIGMVAGGIAGAIPGILRAYLGTSEVIVTIMMNYIILYVGNAIIQRGY
                     PESVKQSIDSTIQVSDNASYQSQWLSDLTNNSRINIGIFFALIAIAVIWFLLNKTTLG
                     FEIRSVGLNPHASEYAGMSLKRTIILSMIISGALAGLGGVVEGLGTFENVFVQGSSLA
                     IGFDGMAVSLLAANSPIGIFFSSFLFGVLSIGAPGMNIAGIPPELVKVVTASIIFFVG
                     AHYLIERYIIRPKKLVKGGK"
     gene            8615..9571
                     /locus_tag="TV188_001522"
     CDS             8615..9571
                     /locus_tag="TV188_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002268043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1534860.1"
                     /translation="MSLVTIFALLVSSMLIYATPLIFTSIGGTFSERAGVVNVGLEGI
                     MVMGGGSGIVFNLEFAHIFGKATPWLAVLVGGVVGLIFSLIHALATINFRADHIVSGT
                     VLNLLAPSLAIFLVKVMYGKGQTDNIQQSFGKFDFPILSKIPVLGDIFFRNTSLVGYL
                     AVAFSFLAWFVLYKTRFGLRLRSVGEHPQAADTLGINVYLMKYYGVMISGFLGGIGGA
                     VYAQSISVNFAVTTILGPGFIALAAMIFGKWNPVGAMLSSLFFGLSQSLAVIGAQLPV
                     LEKIPTVYLQIAPYLLTIIILAAFFGQAVAPKADGVNYIKSK"
     gene            complement(9609..10865)
                     /locus_tag="TV188_001523"
     CDS             complement(9609..10865)
                     /locus_tag="TV188_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEL1534861.1"
                     /translation="MEHLNNTTQLIGIKDKHITLTKAIQHDTHIEVIATLDYNPPKCK
                     LCAGKQIKYDFQKPSKIPFIEIGGFPSLIRLKKRRFQCKSCRKVTVSETTLVKKNCQI
                     SEIVRQKIAQLLLNRKALTHIASKLAISTSTVYRKLKQYHFREDYANLPEVLSWDEFS
                     YQKGKLAFIAQDFNTKKIITILDNRRQTTIRNHFFKYSKEARNKVKVVTVDMSGSYIP
                     LIKILFPKAKIVLDRFHIVQHINRALKQIRSDIMKPFDKKSLKYRALKYYWKLIQKDS
                     RKRSLKPFYSRTFRQTLTPRECLNKIFSLVPELNSYYDLYQLLLFHLQEKNAKHFFGL
                     IHDTLPHLNQTFKTALNTFSRYQDYITNAIQLPYSNAKLEATNKLIKDIKRNAFGFRN
                     FDNFKKRIYLALNITKEKTTFVFSRA"
     gene            complement(11385..13100)
                     /locus_tag="TV188_001524"
     CDS             complement(11385..13100)
                     /locus_tag="TV188_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEL1534862.1"
                     /translation="MTYTENYQKWLDIPDLPAYLRDELLSMDEKTKEDAFYTNLEFGT
                     AGMRGYIGAGTNRINIFVVRQATEGLAALVESKGEAAKKAGVAIAYDSRHFSPEFAFE
                     SAQVLAAHGIKSYVFESLRPTPELSFAVRHLGAFAGIMVTASHNPAPFNGYKVYGSDG
                     GQMPPADADALTDYIRAIDNPFAIRLADLEKAKANGLIEVIGEAVDLAYLEEVKKVNI
                     NQDLINDYGRDMKIVYTPLHGTGEMLARRALAQAGFKSVQVVEVQAKPDPDFSTVKSP
                     NPESQEAFTLAEELGRQVDADVLVATDPDADRLGVEIRQADGSYRNLSGNQIGALIAK
                     YILEAHQQAGTLPNNAALAKSIVSTELVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNYTYMFGFEESFGYLIKPFVRDKDAIQAVLLVAEIAAYYRSRGLTLADGIDDIYKE
                     YGYFAEKTISVTLSGVDGAAEIKQIMDKFRKHAPAQFNHTDIVLTEDFLSQTATHKAG
                     QTQLTTPPSNVLKYTLADDSWFAVRPSGTEPKIKFYIATVGDTLALAEEKIANIESEI
                     NAFVS"
BASE COUNT         3781 a         2330 c         3062 g         4041 t
ORIGIN      
        1 gcgatcaaga cgcagaacag gggctatagc agcctgatgt gagacaggaa ggacttactg
       61 tcctaccagc tacagtcact acactgctag agcttgcggt gtgagcagca gtaagaggca
      121 aaggcgttac cccagaggga ttgatggatc accatcacta gtttggagcc attagctgtg
      181 ccaaaggttt tctaaagcca aaaagaaaaa actccgattg gagttttcat tggttatgta
      241 ttagctaagc tttgcagcaa gacgtgcttt atcgcggctt gctttatttt tatgaatcaa
      301 accttttgat tgggctttat caatgcttga agaagcagcg cggaaaagct cttcagatgg
      361 gttagcttca aatgccttga tagcagtacg catagctgat ttttgtgctg aatttttttc
      421 gtttgcttta acgttaagct cagcgcgttt aatagctgat ttaatatttg ccaatgtttt
      481 cacctccaaa ttaatctaac tacaccatta tatagaaaat ataggtgttt ggcaagcact
      541 tatcactttt tgagataaat ttcatcaatt ttatggtctg cagctttatg aagaatgagc
      601 tcagctcgat tgcgtgtagg ctcaataaac ttttccagat tttctaggtt aattgttttc
      661 cagacttttt ttgcaaaggc aatggcttca ttttgtggca atgaggtata tctagtgtaa
      721 tagttagccg gatcatgctt agccagctct aaaaggctta agaaccgttc caaataccat
      781 tgctcaatat gatggctatc tgcgtcaata taaattgaaa aatcaaaata atcactcata
      841 tacaatcgat tattctgttg attttgaaaa acattaatcc cttcgatgat gaggaagtca
      901 ggattggtaa aggtttgctg ctgatcagga acgatatcat aaatctcatg cgagtaaaca
      961 ggggctgatg cggtttgtcc tcccttgaca gtatccagaa agtttaacaa tagctccata
     1021 ttataggatt ctgggaagcc ctttcgattc agcatattgt ttttgatcag tgtgctatta
     1081 gggtacaaaa aaccatctgt tgtgaccaac tcaacagtgc tggtcttgtg tgtgcgcgcc
     1141 aaaagaagct gcaataacct gctagttgtg gacttaccga cggcaactga gccagaaatc
     1201 ccaataataa agggtctttg ctgaatatct ttttttagaa agaggctttt agaaaaagac
     1261 aggttttctt gagcgatttt atagacttga atgagatgaa tcaagggaag gtaaacctca
     1321 acaacgtcgt tgatatcaat attatcattc aaactggtga tgctagtaag ctcctcttga
     1381 gtcaataagg gcttgctttt ttgatgtaat tgcttccagg attttctgga aattttttca
     1441 aaagtaataa attcgtttga catagttact cctactaatt ggcagtgctt acattataac
     1501 atgtcaataa aaaaattgaa aaatgtttcg tctgaaattc ttaaaaaaac actgaaaaac
     1561 cctataaaaa tcgaacaatt ttagcctaac aattggctaa tataaagtta atcggtcaat
     1621 gttcggaata tatggttcga taaacgaaaa accaagaaaa acaaacgtct tgtaaaccat
     1681 ttcaaagtgt gatagaatga aaaagcatcg aaaaaagata ggaaaacaca tgacaaaaat
     1741 gtattatgat gaaaatccag atagtgctca tgatatccat caattgacgg tcaatttgtt
     1801 aggacagtcc tttacttttt tgacagattc tggtgttttc tcaaaaagaa tggttgattt
     1861 tggaagtcag gtcctgctca acacattaga ttttcaagaa ggtgatcgtc tgcttgactt
     1921 gggctgcggc tatgggccgc taggacttag cttggcaaag gctcaaggtg ttgaggcgac
     1981 tctagtagat attaatcatc gcgctgttgg cttagctaag cagaatgctg agagtaatca
     2041 ggttgaggcg accatttttc aatcaaacct ctatgacggt gtgacaggga catttgagca
     2101 catcattagt aacccaccta ttagggcagg gaaaaaagtg gttcatgaga ttattgaaaa
     2161 gagtattgat tttttaacta aaggcggtga tttgacagtc gttatccaaa agaagcaggg
     2221 agcaccaagt gctaaagaca aaatggaggc cgtttttggg aatgtgacta ttctcaaaag
     2281 agaaaagggt tactacattt taagaagtat taaggaaagg aattgagctc aagtgtaaaa
     2341 agtggtatta aaaagcatag cggtatttta gtaagagttg ccttctaata tcactatttt
     2401 ctcagagctt ttggtatctt gttgatgaga gcagttgatt taatccaaaa aaagcgtgat
     2461 ggtaaagagc tatctaccga agagatccag tggctgatta atggttatgc caatggtact
     2521 gtgccagatt atcaaatgtc ggcttttgca atggcgatct atttcaaggg aatgtctaca
     2581 cgagaaactc gcgatttgac catgagtatg gttgagacag gtgagcagat tgatttgtca
     2641 gctatagctg gtatcaagac ggacaagcac tcaacaggtg gtgttggtga taaggtgaca
     2701 ctcatcttag ctcctctagt tgctagcttt ggcgttcctg tagcgaaaat gagtggacgc
     2761 ggcttaggcc acaccggtgg aacgcttgat aagctagaat ctatcaaggg ctttcagatt
     2821 ggtcggaccc aagaggaatt tatcaagcag gtacaagaga tcggactttc agttattgga
     2881 caatcagata agcttgtgaa ggcagataag ctgctttatg ctcttcgtga tgtgacggca
     2941 accgttgata ttgttccttt gattgcaagc tctgttatga gtaagaaaat tgctgctggc
     3001 gctgatagta ttttgctaga tgttaccgtt ggtgacggtg cctttatgaa gactattgaa
     3061 gatgctgaga agctgtctag actgatggtt gaccttggta aggaggttgg gcgtcagaca
     3121 gtggctgtca ttacagatat gagtcagcct cttggtcgtg ctatcggtaa tcgcttagag
     3181 gtgctagagg caattgatat catgaaaggc aagggacgca aggatattac tcactttatt
     3241 tgtgagctag ctcagattat gctggagctt gctggtgctc aacactctct tgaggatatt
     3301 caccatcatt tggttggcgg agcagcctta aaaaaattag aagagatggt tgtttatcaa
     3361 ggaggtgatc ttgaggacct ttatcgtcca tcacaggcgg ctgttcaaac agaggttttt
     3421 gcgtcagaag atggttacat cacagcattg cctgctcttg agtttggatt gtttgcaatg
     3481 aggctgggtg ctggtagagc agtcaaaaca gatagtctgg attatgaaac agggattgtc
     3541 tttgacaaga aggttggtga cgctgtcgct aagggagagc gcattgcagt tgtcttttca
     3601 caggaagccc tagacgaaaa aatgcttaca gaatttgaaa aaaatgttaa aataggggcg
     3661 gaacacctag aggctaacga aattatcaaa atcatttcct aaggaggagt ataacatgaa
     3721 tattaacaag tatattgacc acacactact aaaagctgac agcgttcaat cgcagcttga
     3781 ccaattaatt gaggaggcta aagcctatga ctttgctagc gtttgcgtca acccttgctg
     3841 ggtagcctat gctgcaaagg ctttaaaggg aacagatgtt aaggtttgta cagttgttgg
     3901 ttttccttta ggtgcaacta cctcagcaac aaaggccttt gaaacaaagg acgctattga
     3961 aaatggtgct gatgagattg atatggttat caatattggt ctgttaaagc agggtgacta
     4021 ccaagctgtt gaagatgata tgcgtgcagt ggtagaggct agcggagaca aattagtcaa
     4081 ggtgattatc gaggcttgcc tcttgactga tgatgaaaag gttaaggctt gtcagttggc
     4141 ggtaaatgca ggtgttgact ttgtgaagac ctctactggt ttttcaactg gcggtgcaac
     4201 cgtttctgat gtcaagctaa tgcgtcaaac agttggtcca gacattggcg taaaggcagc
     4261 tggtggtgct cgttctctag aggacgcttt agcttttgtc gaagcaggag ctacacgtat
     4321 tggaacttct gcaggggtaa ctattatgaa aggtgaagtt gccaatggag gctactgatt
     4381 tagtttcgtt agccattgaa gctagtaaaa gggcttatgt gccttactca catttcccga
     4441 tcggagctgc tttaaagaca aaggacggaa caatctatac tggcaataat atcgagaatg
     4501 ccagctttgg cttgaccaat tgtggggagc gaacagctat ttttaaggct gtttctgagg
     4561 gacatcagca gcttttagaa attgccattt atggagagac tgatgagcca atctctcctt
     4621 gtggagcctg tcgtcaggtc atggcagaat tttttgaagc cactgctcca gtaacgctaa
     4681 ttgctaagga cggtcgtacc atgcgcacaa ctgttggcga gttacttcct tattcgttta
     4741 cagatttatc gtaatctggc ttaattttgt tatctagcca ttaggcttta tatttacttt
     4801 cggcaattgg tttgctagaa atatttttag gagggttcat attcatgaac aagaaattta
     4861 ttggtgttgg tttagcttct gtagctttat taggtttagt tggttgtggt aatcgtaacg
     4921 cttcaaaggg atctggtgat gctaaaacag atttgaaggt agcagtggtt actgacactg
     4981 gtggtgttga tgataagtca tttaaccaat cagcttggga aggcttgcag gcttggggta
     5041 aggacaatgg actaacaaag ggttcaggct ttgattactt ccaatctaca aacgagtctg
     5101 aatatgcaac taacattgat acagcagttt ctagtggtta tgaggttgtt tatggtatcg
     5161 gatttgcctt gaaggatgca atcagtaagg ctgctgatga caacaacaaa gtacaatttg
     5221 ttatcattga tgatgttatc gaaggcaaag acaatgttgc tagcgtaaca tttgctgata
     5281 acgaagctgc ttaccttgca ggtattgcgg cagctatgac tacaaaaaca aaaacagttg
     5341 gttttgtagg tggtatggaa ggaacagttg ttacacgctt tgaaaaaggc tttgaggcag
     5401 gcgttaagtc tgttgatgac tcaatcaaga tcaaggtgga ctacgctgga tcatttggag
     5461 atgccgctaa gggtaagaca attgcagcag cgcaatacgc agcaggtgct gatgttatct
     5521 atcaggtagc tggtggaaca ggtgcgggtg tcttcaacga agcaagaaca attaacgaaa
     5581 aacgtgacga agctgataag gtttgggtaa ttggtgttga ccgcgaccaa aacgaagaag
     5641 gtaaatatac atctaaggat ggcaaatcat ctaactttgt acttgcatct actataaaag
     5701 gtgttggtaa ggctgttcaa ttgatcaata agcaggcagc agataagaaa ttccctgcag
     5761 gtaaaacaac tgtttatggt ctgaaggacg gtggtgttga gattgccaca acaaatcttt
     5821 ctaaagacgt tatcaaagcc atcgaagaag cgaaagaaaa aattaaatct ggtgacgtaa
     5881 aagttcctga aaagtagtta ctggaaaaga gcgaccttcg tcggtcgccc tttttagagt
     5941 ggaacacctt ttgcttcagt aaaggttgtg acaaatggct ggctttactg aaacaaaaga
     6001 ttaaattgaa aggaaataat cctatggcac agcatgtcat tgaaatgaaa gagattacaa
     6061 aaaaatttgg tgattttgtt gcgaatgacc atattaattt gaatgtcaga aaaggcgaaa
     6121 ttcatgcatt gttaggagag aatggtgcag gtaaatcaac gttaatgaat atgttagctg
     6181 ggcttttaga gccaactagt ggaaacattg tcattaacgg tcagcctgtt gttattgact
     6241 ctccttccaa atctgctaga ttgggtattg gaatggtaca ccagcacttt atgctagtag
     6301 aagcttttac agttgctgag aatatcattt taggaaatga agttgtcaaa aacggttgtc
     6361 ttgatttaaa aaaggccagc aaggacatta aagagctttc tgagaaatat ggtttagctg
     6421 ttgatcctac tgccaagatt gctgatattt ctgtaggggc acagcagcgt gttgaaatct
     6481 taaagacctt atatcgtggt gcagatattc ttatttttga tgagccaaca gctgttttaa
     6541 cgcctgctga aatacaagag ctcatggaaa tcatgcgtaa ccttgttaag gaaggcaaat
     6601 ccattatttt gattactcat aagctggacg aaattagagc agttgctgat agagtcactg
     6661 ttattcgacg tgggaaaagt attcaaacag tagatgtagc aggtgcaacc tctcaggact
     6721 tggctgaaat gatggttggg cgttcagttt cctttacaac agctaaaaag gcagcagagc
     6781 caaaaggggt ggtgctgtcg atcaagaatt tagaggtcga tgaaaatcgt ggaatcccag
     6841 cagtaaaggg gctttctctt gacgttagag ctggtgaaat tgtggggatt gcagggattg
     6901 atggtaatgg tcagtcaggg ctgattcagg ccattacagg cttgagaaag actagatctg
     6961 gtagcattac aatcaaaggt caggaggttg ttcatttaag ctcccgtaaa atcacagagc
     7021 tatcagtggg gcatgtgcct gaggaccgtc atagagatgg cttagtgctg gacctttcct
     7081 tggctgaaaa tactgccctt cagacctatt ataaagagcc actaagtaag aacggtattt
     7141 taaattacaa tacaatcaat gattatgctc gtagactgat gaaggaattt gacgttcgtg
     7201 gtgccaatga attggttcca gctcgtggat tttctggcgg taaccaacaa aaggctatca
     7261 ttgcacgtga ggttgaccgt aaccctgatt tattgattgt cagtcagcca actcgcggct
     7321 tggacgttgg tgctattgag tacattcata agcgtttgat tgaagagcgt gacaaaggca
     7381 aggccatcct cgttgttagc tttgagcttg acgaaatctt gaatttatct gaccgtattg
     7441 cagttattca tgacggtaaa attcaaggca ttgtgttgcc tcaagatacc aataagcaag
     7501 aattgggaat tttgatggct ggtggttcca ttgataagga ggagagtcat gtctaaaaat
     7561 gcacaaaaga ttgctgtgcc aatgatttct atcttgttag gattcttact tggcgctatt
     7621 gtcatgttta tctttggcta tgatccaatt tggggctatg agggcctatt tcaggtagcc
     7681 tttggtagta tcaaaaatat tggtgaaatc ttcagagcga tgggaccact aatcctgatt
     7741 gcacttggtt ttaccgttgc tagccgtgcc ggcttcttta atgtcgggct gtcaggtcaa
     7801 gctttggctg gttggattgc tgcgggctgg tttgctcttg tcaatcctaa tatgcctcgt
     7861 ccgcttttaa ttctgatgac tgtcttgatt ggtatggttg ccggcggaat tgctggcgct
     7921 attccaggta ttttgcgagc ttatcttggt acgagtgaag ttattgttac cattatgatg
     7981 aattatatta ttctgtatgt cggtaacgct atcattcaaa gaggctaccc tgaaagtgtt
     8041 aagcaaagta ttgattcaac catacaggtc agtgataatg ccagctatca aagtcaatgg
     8101 ctgtcagatt taaccaataa ttctcgtatt aatatcggta tcttttttgc gcttattgca
     8161 attgcagtta tttggttctt actaaacaaa acaaccctcg gatttgaaat tcgttcagta
     8221 ggtcttaatc cacatgcttc agaatatgca ggtatgtcct taaagcgtac gattatccta
     8281 tcaatgatca tttcaggtgc tttagcaggc ttgggaggag ttgttgaagg cttgggaacc
     8341 tttgagaatg tttttgtaca gggaagctct ctagcaattg gttttgacgg tatggctgtt
     8401 agcttgcttg ctgccaattc accgattggt atcttcttct catcattcct atttggggtg
     8461 ttgagcatag gtgctcctgg tatgaatatc gcaggaattc caccagaatt ggtaaaagta
     8521 gtgactgcct caattatctt ctttgtaggt gctcactacc ttatcgaacg ctatattatc
     8581 aggcctaaaa aactagtaaa gggaggtaaa taagatgagt ttagttacta tttttgcttt
     8641 attggtttca tcaatgctta tctatgctac acctcttatt tttacaagta ttggtggtac
     8701 cttctcagaa cgagctggtg ttgtcaatgt cggccttgaa ggcattatgg tcatgggggg
     8761 gggttcaggc attgtcttta atcttgaatt tgctcatatc tttggtaaag ctactccctg
     8821 gcttgcagtt ttggtgggag gagttgttgg attgatcttt tcattgatcc atgcgcttgc
     8881 aacgattaac tttagggcag atcacattgt cagtggtaca gtgctaaatc tgctggcacc
     8941 atcgcttgcc attttcttag ttaaggtgat gtacggtaag gggcaaactg ataatatcca
     9001 gcaatcattc ggtaagtttg attttccgat tctctcaaaa attccagttc ttggagatat
     9061 attctttaga aatactagct tagttgggta tttagctgtt gccttttctt tcctagcttg
     9121 gtttgtgctt tacaaaacaa gatttgggtt gcgtttgcgc tctgtaggtg aacaccctca
     9181 agcagctgat acacttggta ttaacgttta cctcatgaaa tattatgggg ttatgatctc
     9241 tggttttctt gggggtattg gtggagctgt ctatgcacaa tccatctctg ttaacttcgc
     9301 agtgacaacc attttaggac ctggatttat tgcccttgcc gctatgattt ttggtaagtg
     9361 gaatccggta ggtgctatgc tatctagctt gttctttgga ttatcacaaa gcttagcagt
     9421 tattggggca caattaccag tattggaaaa aatcccaacg gtttaccttc aaattgcgcc
     9481 atacctattg accatcatca ttttggctgc tttctttgga caagcagtgg ctccaaaggc
     9541 agacggtgtt aattacatca aatcaaaata aaaaaagctc aatgtcaact gtagtgggtg
     9601 actgatagct aagcacgaga gaagacgaat gtcgtcttct cttttgtgat attcaaagcg
     9661 aggtagatac gttttttaaa gttgtcaaag ttccgaaatc cgaaagcatt gcgcttgata
     9721 tctttgataa gtttgttagt ggcttctaac ttagcgttag aataaggcag ttgaatggca
     9781 ttggtgatgt aatcttggta gcgactaaag gtatttagag ctgttttaaa agtctgatta
     9841 agatgtggta gtgtgtcatg aattaaacca aagaaatgct tggcattctt ttcttgcagg
     9901 tgaaaaagga gcagctggta caggtcataa taagagttta actcaggcac tagtgagaag
     9961 atcttattga gacattctct aggagttaag gtttgtctga aggtgcggga atagaaaggc
    10021 ttaagagacc gttttctgct atccttttga ataagcttcc agtagtactt aagagctcta
    10081 tatttaagag acttcttgtc aaatggtttc atgatgtcac tacgtatttg cttgagagct
    10141 ctattgatgt gctggacaat gtgaaaacga tcgagaacga ttttagcctt aggaaataga
    10201 attttaatga gaggaatata acttccagac atatcgacag tgacgacttt caccttgttt
    10261 ctagcctctt tagagtactt aaagaaatga tttcggatgg ttgtttgacg tctattatca
    10321 agaatggtaa tgattttctt agtgttaaaa tcctgagcaa tgaaggctaa tttacctttc
    10381 tgataagaga actcatccca agagagaact tctggcaaat tggcgtaatc ctctcggaaa
    10441 tgatactgct taagcttgcg atagacggta gaagtggaga tagcgagctt agaagcgata
    10501 tgggtgagag cctttctgtt gagtaaaagc tgagcgattt tctgtctcac tatctcagaa
    10561 atttggcaat ttttcttaac cagggtagtt tcagatacag tgacttttcg acaggatttg
    10621 cattgaaacc ttcttttttt caaacgaatg agactaggaa agcctccaat ttcgataaag
    10681 ggaattttag agggcttctg gaagtcgtat ttgatttgtt ttcccgcaca cagtttacat
    10741 ttaggagggt tatagtctag tgtagcgatg acttcaatat gagtatcatg ctggatagct
    10801 ttagtcaagg tgatatgttt gtctttgatt ccaatgagtt gtgtggtatt attgaggtgt
    10861 tccataagat accttctaaa tgatagttta gtcgcttttc atgataagtc ttatgggact
    10921 tttttgatac tcaaaaagcc ctataatctc cacagtagcc ttacccacta cagaaattat
    10981 agagccatct tagaacactg gacttgttcg ctttttaatg aattaaattt agtagatcct
    11041 ttaaaggcat gctatcaagc tttttatcct tgacttttgt ttagcaagtg aagtgttcac
    11101 aaaagctagc taaaacactg agctgacaat gtagagaatg gctcgttttg acaaggttag
    11161 agtgcttttt gctgtatggt ttttaatcca cgcacctgaa aaagaaagga caggacctgt
    11221 gcgagcttac ttgtggttag taggtttcaa ttcatgctcc caaaaaggaa gcaacgcaac
    11281 tctgagaaag gtcttagacc actttcccag tttgcctcac agctaatggt gtaaaacaaa
    11341 tagaccaccc tgtaacaggt ggtcatggtt agatatcagc tcatttaaga gacaaaggcg
    11401 ttgatttcag attcaatatt ggcaattttt tcttcggcaa gcgcaagggt gtcaccaaca
    11461 gttgcgatat aaaatttaat ttttggctct gttcctgatg gtcttacagc aaaccatgaa
    11521 tcatcagcta gggtatattt taagacattg cttggaggag tggttagctg ggtttgacca
    11581 gctttatgag ttgccgtctg actgaggaaa tcctctgtta acacaatatc agtgtgatta
    11641 aactgcgcag gggcatgctt gcggaattta tccataatct gtttgatttc agctgcgcca
    11701 tcaacaccag acagtgtaac agaaatggtt ttttctgcaa agtagccgta ttctttgtaa
    11761 atgtcatcaa taccatcagc aagggttagt ccacgagagc ggtagtaggc agcaatctca
    11821 gccaccaata gcaccgcttg aatagcgtcc ttatcacgta caaatggttt aatgagataa
    11881 ccaaagctct cctcaaagcc aaacatatag gtgtaattgt gcttttcttc aaattcttga
    11941 attttttcag caatgaactt gaagcctgtt aagacattaa acatggttgc cccgtagctc
    12001 tctgcaattt tagtcactaa ttcagtagag acaatggatt tggcaagagc ggcattgtta
    12061 ggtagggttc cagcctgctg atgtgcttct aaaatatact tagcaattaa agcaccaatt
    12121 tggttgcctg ataggttgcg atagctgcca tctgcctgcc gaatttcaac cccaagacgg
    12181 tcagcatctg gatcagtagc aacaagaaca tcagcatcaa cctgacgtcc aagctcctca
    12241 gcaagagtaa atgcctcttg actttcagga ttaggagatt tgacggtaga aaaatctgga
    12301 tctggcttag cctgcacctc aaccacctga acggacttaa agcctgcttg tgccaaggca
    12361 cgacgtgcta gcatttcacc tgttccatga agaggtgtat agacaatttt catgtcacga
    12421 ccatagtcat tgatgaggtc ttggttgata ttgacctttt tgacctcttc taaataagca
    12481 aggtcaacag cttcaccaat aacctcgatg agcccattag ctttggcttt ctctaaatca
    12541 gcaagcctaa tggcaaaggg gttatcaatc gcacgaatgt aatctgttag agcgtcggcg
    12601 tcagctggag gcatttgacc gccgtcagac ccataaacct tatagccgtt gaatggtgca
    12661 gggttgtgac tggcagtaac catgataccg gcaaaagcac ccaaatgtcg cacagcaaag
    12721 gaaagctcag gtgttggccg aaggctttca aaaacgtatg atttaatgcc atgagctgct
    12781 agtacctgtg cagattcaaa ggcaaattct ggagaaaaat gacgagaatc ataggcgata
    12841 gcgacaccgg ccttcttagc agcttctccc tttgactcaa ctaatgctgc caagccctca
    12901 gttgcttggc gaacaacaaa aatattgata cgattcgttc cagcgccaat atagccacgc
    12961 ataccagctg ttccaaattc aagattggtg tagaaggcat cttcctttgt tttttcgtcc
    13021 atgctaagta attcatctct taaataggct ggtagatctg gaatatcaag ccatttttga
    13081 tagttttctg tgtaagtcat agtattctcc tttatatttt taaccgcttt cattatatca
    13141 tgttgaaaag gaaaaatcac ttattttctg taatagcttc caatcatttt ttcacataag
    13201 gatcaatttc cttg
//
LOCUS       DARYYD010000050        12984 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.051, whole genome shotgun sequence.
ACCESSION   DARYYD010000050 DARYYD010000000
VERSION     DARYYD010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12984
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.051"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(22..1071)
                     /gene="citC"
                     /locus_tag="TV188_001525"
     CDS             complement(22..1071)
                     /gene="citC"
                     /locus_tag="TV188_001525"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HEL1534863.1"
                     /translation="MTQHLIQHIFPFDKQQKAKIDRLLQRQHIRRDPHLDYTCAIIDE
                     QGEPIATGSLYGNSLRCLAVDQAYQGEGLLNHIVSHLIEEAYSRGHHHLFIYTKIAAA
                     PLLLSLGFHVIAMVDDTLCFLENKKRGFEHYLSQLEKPQISPQKTAAIVLNANPFTLG
                     HLHLIEKACADNELVHLFMVSQDSSLIPYHIRKELIIKGTAHLANIIYHDSGPYMISQ
                     ATFPAYFQKDELAVIDSQAKLDIVIFRHIAEKLQIKSRYVGEEPTSMVTQHYNTVMLK
                     QLPCYSIDVQVIPRKTFAEGKIISASLARQAIKDDDYALLELLLPKTSLDFFRSEAAQ
                     PTITKIKAATDLKHY"
     gene            1338..2401
                     /locus_tag="TV188_001526"
                     /pseudo
     CDS             1338..2401
                     /locus_tag="TV188_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004347311.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
     gene            complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TV188_001527"
     CDS             complement(2487..3371)
                     /gene="citG"
                     /locus_tag="TV188_001527"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HEL1534864.1"
                     /translation="MTKKVFDDISRLALKALLYEVSLSPKPGLVDQLDNGAHDDMSFL
                     TFVDSALALAPFFKIYLDIGFYHAKEDPGLIFERLRASGIEAEQAMFSATKGVNTHKG
                     VNFSLALLLGATGMYLADQPQLLDHVTAFTEEDSLAICQLVKPLTAHLLETDFGSLDL
                     KKELTYGEKLFLDYGIKGPRGEASEGYPTIAHKALPFLRKSLRSTDQETAQLQLLVYL
                     MSIVEDGNLIHRGGIKAWRQVKQDMLLLHNSSLSTADLKAALSAYNDKLIQKHLSPGG
                     TADLLVLSLYFAFLENQL"
     gene            complement(3364..4059)
                     /locus_tag="TV188_001528"
     CDS             complement(3364..4059)
                     /locus_tag="TV188_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1534865.1"
                     /translation="MNPIIEAVKNNLDLSRNIPLKIAFYNALKKTIILRQIPAGSRIN
                     EKEFSIALNISRTPIRYALGLLSEEHLVEHIPKKGIIVKGVSIQDACEIFEIRKALET
                     LATSTAMYLMTEEDFQVMHDLLADCETFIEDDDLNRILDNFNSFNNLIYSYSQMVRLK
                     EIVTELQTYLVYFRKISISSLERRKRALSEHWMIYRGMKNRDHEQITLITHEHLNSSL
                     EFILQEMSRRQDD"
     gene            complement(4212..5615)
                     /locus_tag="TV188_001529"
     CDS             complement(4212..5615)
                     /locus_tag="TV188_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003088270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HEL1534866.1"
                     /translation="MLLTVLAYAMIIIFMYVVMKKKMTPFTALVMIPLIMTIAVILTG
                     SADFTSDAKFVAFVGEDGLAKNLTAIGPMIMYGINNTAKTGIMLLFAILFFSIMLDAG
                     LFDPITEKMIRFAKGDPMKVLMATAIVAAAVSLNGDGTTTTLICCSAFLPIYKKLNMR
                     IMNLGVLIILQNTIMNLLPWGGPTARAMSVLSVGPEILGYLAPGMVLSLLYVICWVAP
                     SMGRKERARLGVVDLTEEEMRKLTDITDPDTLSIRRPKNFAFNAILTIGLITWLVAGS
                     FYKAIAMAPLLLFAVGTCIALIVNYPVLKDQTKRIGDNAGDAVQVVILVFAAGIFMGL
                     FQGSGMASALAQSFATIIPKQLAGFWGLVIALISAPGTFFISNDGFYYGILPVLAEAG
                     AEYGFSNMAMALASLMGQAFHLLSPLVAFIYLLLRLTGLDMGEWQKEAAKYAIIIFII
                     FVVTIIAMGQMPLYIPQ"
     gene            5997..6341
                     /locus_tag="TV188_001530"
     CDS             5997..6341
                     /locus_tag="TV188_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534867.1"
                     /translation="MQFFQNMFRRSKKEAATSHQDRENKPEFPLDDWEPVPSYIAADK
                     KDYQTVSLIASAIAAGEQASSQFKVKRILQRNPEALTVSLIASSIAAGVYPESQFLVR
                     SIYSKKVNVSHK"
     gene            6359..6754
                     /locus_tag="TV188_001531"
     CDS             6359..6754
                     /locus_tag="TV188_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HEL1534868.1"
                     /translation="MLRKFKITIDGKEYLVEMEEIGAPSQAPVVPPVQPAVAPAPVAE
                     KKAAEAPQAPAAPVSAGADAMPSPMPGIILKVLVNVGDVVHENQPLLILEAMKMENEI
                     VASTAGTVTGIHVTAGQVVNPGEGLITIS"
     gene            6804..7925
                     /locus_tag="TV188_001532"
     CDS             6804..7925
                     /locus_tag="TV188_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ion-translocating decarboxylase subunit
                     beta"
                     /protein_id="HEL1534869.1"
                     /translation="METLIAGVTSITIPQIIMMLIGAVLMYLGIKKEYEPTLLVPMGL
                     GTILVNFPGTGVLTQVVNGVEQEGVFDALFNFGIGTELFPLLIFIGIGAMIDFGPLLQ
                     NPFMLLFGAAAQFGIFFVVVVAVLAGFDIKEAASIGIIGAADGPTSIFVANQLAKDLL
                     GPITVAAYSYMALVPIIQPFAIKLVTTKKERRIRMTYKAENVSQLTKILFPIVITLVA
                     GFIAPISLPLVGFLMFGNLLRECGVLDRLSQTAQNELVNIISILLGLTISIKMQAELF
                     LNVQTLLIIIFGLLAFIMDSIGGVMFAKFLNLFRKEKINPMIGAAGISAFPMSSRVIQ
                     KMATDEDPQNFILMYAVGANVSGQIASVIAGGLLLAYFS"
     gene            8107..8415
                     /gene="citD"
                     /locus_tag="TV188_001533"
     CDS             8107..8415
                     /gene="citD"
                     /locus_tag="TV188_001533"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HEL1534870.1"
                     /translation="MEIKQIAVAGSLESSDMMITISPNDGQGIVLELDSSVEKQFGNH
                     IRALIKTTLARLGVESATIEAVDKGALDCTIQARTIAAVHRAAGVEHYNWKEIDSWNA
                     "
     gene            8403..9290
                     /gene="citE"
                     /locus_tag="TV188_001534"
     CDS             8403..9290
                     /gene="citE"
                     /locus_tag="TV188_001534"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HEL1534871.1"
                     /translation="MERLRRTMMFVPGANAAMLRDAPLFGADSIMFDLEDSVSLKEKD
                     TSRALVHFALKTFDYSNVETVVRVNSLDSCGALDIEAVVLAGVDVIRLPKTETAQDII
                     DVEAVIERVERDNGIAVGRTRMMAAIESAEGVLKAREIAKASNRLIGIALGAEDYVTN
                     MKTRRYPDGQELFFARSMILHAARAAGIAAIDTVYSDVNNTEGFQAEVRHIKQLGFDG
                     KSVINPRQIPLVNEIYTPTEKEISHAKQVIWAIREAESKGSGVISLNGKMVDKPIVER
                     AQRVIALATAAGVLTEEDI"
     gene            9292..10824
                     /gene="citF"
                     /locus_tag="TV188_001535"
     CDS             9292..10824
                     /gene="citF"
                     /locus_tag="TV188_001535"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HEL1534872.1"
                     /translation="MVKNKLGRDIPQEYADHYGVFEGELARITSYNESSRRIKPVKPG
                     DSKLLGSIREAIEKTGLKDGMTISFHHHFREGDFVMNMVLDEIASMGIKDLAIAPSSI
                     ANVHEPLIEHIKNGVVTSITSSGLRDKVGAAISSGIMEKPVVIRSHGGRARAIASGDI
                     HIDVAFLGAPSSDEYGNVNGTIGKATCGSLGYAMIDAKYADQVVVLTDHLVDYPNTPI
                     SIPQTDVDYVVTVDAIGDPQGIAKGATRFTKNPKELLIAEYAAKVITQSPYFKNGFSF
                     QTGTGGASLAVTRFMREAMLQENIKASFALGGITNAMVELLEEGLVEKILDVQDFDYP
                     SAVSLGKNAQHYEIDANMYASPLSKGSVINQLDTCILSALEVDTNFNVNVMTGSDGVI
                     RGASGGHCDTAFAAKMSLVISPLIRGRIPTFVDEVNTVITPGTSVDVVVTEIGIAINP
                     NRPDLIEHFKDLKVPQFSIEELKEKAYSIVGTPDRIQYGDKVVALIEYRDGSLIDVVY
                     NV"
     gene            10817..11377
                     /gene="citX"
                     /locus_tag="TV188_001536"
     CDS             10817..11377
                     /gene="citX"
                     /locus_tag="TV188_001536"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HEL1534873.1"
                     /translation="MSKELIFKGKAVTLADMLRAREDRSLRQGKLLTEFSNESLLSVT
                     MNIPGPIKTSPALLEVFDSVIKAILEKLSGNQISYQLRLLPKTGYEYYLVTALDSQAL
                     KLKMIELETDLPIGRLMDLDVLVLTNQLPTPISRTALGFPPRSCYLCSKEAKACSRNR
                     SHSVADMQTALVHLLQSFFDGGNQLS"
     gene            11408..12799
                     /locus_tag="TV188_001537"
     CDS             11408..12799
                     /locus_tag="TV188_001537"
                     /EC_number="4.1.1.112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxaloacetate decarboxylase subunit alpha"
                     /protein_id="HEL1534874.1"
                     /translation="MTKIRITETVLRDGQQSQIATRMTTKEMIPILETLDNAGYHALE
                     MWGGATFDSCLRFLNEDPWERLRTIRKVVKKTKLQMLLRGQNLLGYRNYADDVVRSFI
                     QKSIENGIDIVRIFDALNDPRNLETAVSATKEFGGHAQVAISYTTSPVHTIDYFVALA
                     KAYQAIGADSICIKDMAGVLTPETGYQLVKRIKESIALPLEVHTHATSGISEMTYLKV
                     VEAGADIIDTAISSFAGGTSQPATESMVIALEDLGIDTGVDMTRLTKIAEYFNTIRDH
                     YRAEGILNPKVKDTEPKTLLYQVPGGMLSNLLSQLKEQGLSDKYEEVLAEVPKVRADL
                     GYPPLVTPLSQMVGTQALMNVISGERYKVVPNEIKDYVRGLYGQPPAPLGEGIKEKII
                     GDEAVITCRPADLIEPQLPLLRQEIAGYACCEEDVLSYASFPQQAKDFLGRREDPFYD
                     IPVQYVTVDIAMD"
BASE COUNT         3802 a         2590 c         2874 g         3718 t
ORIGIN      
        1 tagagagggg gtagttgttg gttaataatg cttaaggtct gttgctgctt tgatcttagt
       61 tatcgtgggc tgagcagcct cgctcctaaa aaagtcaagt gaggtcttag gaaggagtag
      121 ctctaagaga gcataatcat cgtccttgat ggcctgtctg gcaagagagg cgctgatgat
      181 tttgccttct gcaaaggttt ttctagggat aacctgcaca tcaatgctat agcaaggcag
      241 ctgcttgagc atgacagtgt tgtaatgctg tgtgaccatg ctagtaggct cttcgccaac
      301 ataacgactc ttgatttgga gtttttctgc aatgtgacgg aaaatgacaa tatccaattt
      361 agcttgacta tcaataactg ctagctcatc tttttgaaaa taagcaggaa aggttgcctg
      421 actaatcatg taaggtccac tatcgtggta tatgatattt gctaggtgtg cagttccttt
      481 gatgattaat tcctttcgga tatggtaggg gatcaggcta ctgtcttgac tgaccataaa
      541 gagatgaacg agctcgttgt cagcgcaggc cttttcaatc agatgcagat gaccaagggt
      601 aaatggatta gcatttaaaa cgattgctgc ggtcttttga ggactgatct ggggcttttc
      661 tagctgtgac aggtagtgct caaagcccct ttttttattt tctaaaaaac aaagagtatc
      721 atcaaccatt gcaatgacat gaaagccaag acttagcaat agaggggcag ctgctatttt
      781 agtgtagata aacagatgat gatgcccacg tgagtaggcc tcctcaatca gatgtgagac
      841 aatgtgatta agtaagcctt ctccttggta ggcttgatca acagctaagc agcgcaggct
      901 attgccgtac aaagagccag tagcaatagg ctcgccttgc tcgtcaataa tagcacaggt
      961 ataatctaaa tgagggtctc ttctaatgtg ctgtctttgt aacaaacgat caatttttgc
     1021 tttttgctgc ttgtcaaagg gaaaaatatg ctgtatcaag tgctgcgtca tatgctcacc
     1081 tcttattacg aaattatcct cttgccttta ttatagcacg ctatagggct tattcttaag
     1141 catcttagct ggtttatgaa aagaatgcac aaaaaagaca tcaatgacct attgtctctg
     1201 atgtcattat gatatgatta ggacttttag ataaatgatt aaggtatgga ggatttaagc
     1261 ctgcaaaagg tggcaataat aattctgact tatgctataa tagagctatt gatattaagg
     1321 gggataaagg ggctggtatg ctttcgattc taatgacttt atttgttggg acgctgggag
     1381 ggcttgttgc taagcggctg agtattcctg ccccttttat gattggcagt atggtagctg
     1441 ttgccctagc ttctatcctg acaaagcagg tagaggctat taaccccatg aagatttttg
     1501 ctcagattat tagtggtgcc tatattggcc aaagcgtcag caaatctgac ctgcttaatc
     1561 tgcccaagct agccaagtct attattagtc tcatgtcctt gttcacgctg aatatgtttc
     1621 ttcttggtgg ggtatttgtt tactgctttg atcttgatcc tgtaacagcc ttgttgagct
     1681 gtttacctgg tggcattatg gacgtttctc ttatggcagt tgatatggga gcaaaggctg
     1741 atatagttgc gacattacag tcggctcgac tggtcggtat gctcttgttt cttcctgttt
     1801 gggtgacgtt ttgggtcaat cgctttgacc caaaagcaaa agctactaaa aaaaaaagat
     1861 agtcaaaagc gctagctccc aagatacaag accttctagg aaagagcagc tatggaataa
     1921 tgtccaggtt ttaagcattg ctaccattgg aggtttgatc ggtttagggc taaagatacc
     1981 tgtaggcgct ctgattgttt ctttgctttt ttcaacagca ctgaaggtgc ttcggcaaac
     2041 aagtcaaatg ccaagtacac ttcgttatat agcgcaggtt tttgctggct ctattattgg
     2101 aacaagcttt actcaggata gtttgcttca aatgggacgt ctgattgttc ctattctttt
     2161 acttttgagt agctatctga tcatcaatct cttttttggc tatatcatgt ataaaaaagg
     2221 tatcttggat ttgcaatcgg cactctttgc ctcatcgcct gctggtgcga cagacatttc
     2281 actattggct ggtgagcttg gcggagatat gcctaaaatc gctggtattc aaatcagtcg
     2341 aaccctctat actgttgtca tcatgccctt gttggttaaa tggctcatta gtatatggta
     2401 aacagaaaag cccctcagag cataaaccag agatacctag tcattaccaa ataacatatc
     2461 aaggatcttg ttcaggcttg gagctgctat aattgatttt ctaaaaaagc aaagtagagg
     2521 cttagcacta gcagatcagc agtccctcca ggactgagat gcttttggat cagcttgtcg
     2581 ttgtaggctg acaaggcagc ctttaagtca gcagtgctca aagagctgtt gtgcaatagc
     2641 agcatgtcct gtttgacttg ccgccaagct ttgatgcctc ctcggtgaat caggttgcca
     2701 tcttccacaa tagacatgag gtaaaccagc agttgcagtt gagcggtctc ctgatcagtg
     2761 ctgcgaaggc tcttgcgcaa aaaaggcagc gccttgtgag caattgtagg atagccctcg
     2821 ctggcttctc ctctagggcc ctttataccg taatctagaa agagcttctc accataggtg
     2881 agctcttttt ttaggtctaa gctaccaaaa tcagtctcaa ggagatgagc tgttagaggc
     2941 ttgacaagct gacaaatagc cagactatcc tcctcagtaa aggctgttac atggtccaag
     3001 agctgtggtt gatcggcaag atacattccc gttgccccaa gcagaagtgc taaggaaaaa
     3061 ttgactccct tatgggtatt gactccctta gttgcgctga acatggcttg ctcagcctca
     3121 atgcctgagg cacgcaagcg ctcaaagatc agaccaggat cttccttagc atggtaaaaa
     3181 ccaatgtcta aataaatctt aaaaaagggg gctaaggcca gagcgctatc aacaaaggtt
     3241 aagaagctca tgtcatcatg agccccgtta tcaagctgat ccacaagccc aggcttagga
     3301 gataaggaca cttcgtaaag taaagccttt agagcaagcc tgctaatatc atcaaatacc
     3361 ttcttagtca tcctgacgcc tgctcatttc ctgtaggata aattctagtg agctgttgag
     3421 gtgctcatgc gtaataaggg tgatttgctc gtggtcacga tttttcatgc cacgataaat
     3481 catccaatgc tcagataaag cgcgttttcg tctttctagg gaagagatcg aaatttttct
     3541 aaagtaaaca aggtaggtct gcaattcagt gacaatttct tttaatctga ccatctgact
     3601 atagctgtaa atcagattat taaagctgtt gaaattatct agaattctgt tgagatcgtc
     3661 atcttctata aaggtttcac aatcagccaa caaatcatgc atgacctgaa aatcttcctc
     3721 tgtcatcaaa tacatagcgg tgcttgttgc cagtgtttca agcgcttttc tgatttcaaa
     3781 gatttcacaa gcatcttgaa tactaacacc cttgacaata atgccttttt taggaatatg
     3841 ctctaccaaa tgctcctctg ataacaatcc tagagcgtac ctgattggtg ttctgctaat
     3901 atttagggca atggaaaatt ctttttcgtt gatacgactg ccagcaggaa tttgtcttaa
     3961 aataatagtt ttctttaggg cgttataaaa agctattttc aaagggatat tgcgggatag
     4021 gtcaagatta ttctttactg cttcgataat aggattcata taatctcctt aatgttcata
     4081 tcatgatatt attatactga aaatcattac taatgaaaat aataattagc ctcctaaaag
     4141 gcgaaagcca tgctcgtgaa agaacatggc tttcattagc ccacactaca gtcctaataa
     4201 tagctcgtga cctattgtgg aatgtaaagc ggcatttgtc ccattgcaat aatggttaca
     4261 acaaagataa taaagataat aatcgcgtat ttagcagctt ctttttgcca ttctcccata
     4321 tcaagcccag taagacgaag aagcaggtaa ataaaggcca ccaatggact gagcaaatgg
     4381 aaggcttgtc ccatcagaga agcaagagcc atcgccatgt tgctaaagcc atattcagct
     4441 ccagcctccg ctaagactgg caaaatacca tagtagaagc catcatttga gataaagaaa
     4501 gtaccaggag ctgaaatcag ggcaataaca agtccccaga agccagccaa ttgctttgga
     4561 ataatcgttg caaagctttg agcaagagca ctagccatac cagagccttg gaaaagtccc
     4621 atgaagatac cagcagcaaa aaccagaata acaacctgaa cagcatcacc ggcattatca
     4681 ccaatacgct ttgtttggtc ctttaggaca ggatagttaa caataagggc aatacaggtt
     4741 cccactgcaa ataaaagaag tggtgccata gcaatagcct tatagaaaga gccagcaacc
     4801 agccaagtga ttaagccgat ggttaagata gcattaaagg caaagttttt aggacgacgg
     4861 atagaaagcg tatctggatc tgtaatgtct gttagcttac gcatttcctc ttcggtcaaa
     4921 tcaacaacac caagtcttgc acgctccttg cgtcccatgc ttggcgcaac ccaacaaatg
     4981 acataaagaa gagacaaaac cataccaggt gcaaggtatc caaggatttc aggtcccaca
     5041 ctaagcacag acatggcacg cgcagttgga ccaccccaag gaagcaggtt catgatagtg
     5101 ttttgcagga taatcaagac accaagattc atgatgcgca tgtttaattt cttatagatt
     5161 ggtaaaaaag cagagcagca aatcaaggtt gttgttgtac catcaccatt aagtgaaaca
     5221 gctgctgcaa caattgcagt tgccatcaag accttcatcg ggtctccctt agcaaagcga
     5281 atcatttttt cagtaatcgg gtcaaacaag ccagcatcta gcataatgga aaagaacagg
     5341 atcgcaaaaa gcagcataat acctgtctta gcagtgttat taataccgta catgatcata
     5401 ggaccaatag ctgtcagatt tttagcaagc ccatcctcac caacaaaggc aacaaatttg
     5461 gcgtctgatg taaaatcagc agagcctgtt aatataacag caattgtcat tatcaacgga
     5521 atcatgacca gagctgtaaa aggggtcatt tttttcttca tgacgacata catgaagata
     5581 ataatcatag cataagctag aactgttaat aacatattgt tatctccttt ttgattttat
     5641 gacttcagta taaatgaaag cgttcgcaaa agaaatacct ccatgtacgg aaaaacacaa
     5701 aaaaaacatt ttgaaagcag atcctgaaaa aataaatggt tacattaatg tttttcaaca
     5761 gcagttagtt gctcttatct tcagtaatcg cagtgtgttt cagcattttt taaaatcagt
     5821 catatttatt ttagttaact gtttttataa aaatggttaa ctaaaataag aaaatccttg
     5881 aaaatgtgaa agcgctctta gaaagaacac aaaaaagcca ttccaaaagg atgaggtggt
     5941 atataataag catagaagct tcccatttgt gggcaaacta agaaaggagg tagcttatgc
     6001 agttttttca aaacatgttt agacgctcta aaaaagaggc agccacaagc catcaagaca
     6061 gagaaaataa gcctgaattt ccgttagatg actgggagcc agtgcctagc tacattgctg
     6121 cagataaaaa ggattatcag acagttagtc tgattgccag tgccattgca gctggcgagc
     6181 aagctagcag tcagtttaag gtaaaacgaa tcctacagcg caatcctgag gccttaaccg
     6241 tatccttaat agcatcaagc attgcagctg gtgtttatcc agagagtcaa tttctggtta
     6301 ggtccattta tagtaagaaa gtaaacgtta gccacaaata gtaaaaggag aaaagattat
     6361 gttgcgtaag tttaaaatta ccattgacgg aaaagagtac ctagttgaaa tggaagaaat
     6421 cggtgctccc tcccaagccc cagtagtacc tcctgttcaa ccagcagtag ctccagcccc
     6481 tgtagccgaa aaaaaggcag cagaagctcc gcaagctcca gcagcacctg tatcagcagg
     6541 ggcagatgca atgccctcac ctatgcctgg tattatctta aaggttttag ttaatgttgg
     6601 tgatgtcgta catgaaaatc agcctctatt gattttagag gctatgaaaa tggaaaatga
     6661 gattgtcgcc tcaacagctg gtacagtcac agggattcat gttactgcag gtcaggtggt
     6721 caaccctggt gaaggcttaa tcaccattag ctaatcctaa gtcgtgtctt gatttaaaat
     6781 gttgtagaaa aggaagtaca tttgtggaaa cattaattgc aggagtaacc tccatcacta
     6841 ttcctcaaat cattatgatg cttatcggtg ctgtcttaat gtatctagga ataaaaaaag
     6901 aatacgaacc aaccttacta gttcccatgg gactgggtac tattttagtc aactttcccg
     6961 gcacaggagt cttaacacag gttgttaatg gtgttgagca agaaggggtc tttgatgcct
     7021 tattcaattt tggaatcggt acagagctgt ttccattact tatttttatc ggtattggtg
     7081 ccatgattga ctttggtcct ttacttcaaa atcctttcat gctattattc ggtgcggcag
     7141 ctcaatttgg gattttcttt gttgtcgttg tagccgtatt agctggcttt gatattaagg
     7201 aagcagcttc aattggtatc attggtgctg ctgacggtcc aacatcaatt tttgtagcaa
     7261 accaattggc aaaggatttg ctagggccta tcacagtggc agcttattct tacatggctt
     7321 tggttccgat cattcagccc tttgcgatca agctagttac taccaaaaaa gagcgtcgta
     7381 ttcgtatgac ctataaggct gagaatgtgt cacaattaac gaagatcctc tttcctattg
     7441 tgatcacact tgtagccggc tttattgctc caatttcgtt accattggtt ggttttttga
     7501 tgtttgggaa cctgcttcgt gaatgtggtg tcttggaccg attgtcacag accgctcaaa
     7561 acgaattggt caatatcatc agtattttac taggactaac catctctatc aaaatgcagg
     7621 ccgagctttt cttgaatgtg caaaccctgc ttattatcat ttttggtctg ttggccttta
     7681 tcatggattc gattggtggt gtgatgtttg ccaaattctt gaatttattc cgtaaggaaa
     7741 aaatcaaccc aatgatcgga gctgctggaa tttcagcctt tccaatgtca agtcgtgtga
     7801 ttcaaaaaat ggccactgat gaggatccgc agaatttcat cttgatgtat gctgtgggtg
     7861 ctaatgtatc tggtcaaatc gcctcagtta ttgcaggtgg cttgctgctt gcttacttta
     7921 gctaagaaag gacgtgctta tgacaatcaa tatagaccat ttgatccaat cctttgagct
     7981 aatggcactt ggaatggcag gagtatttgt tgtattagga attctctata ttgtagcaga
     8041 ggctctgatt aagctatttc cagtagaaaa ataatagaat atgatctaaa caaggaggtc
     8101 aatcaaatgg agatcaaaca aattgctgtt gctggttcgc ttgaatctag cgacatgatg
     8161 ataacaatat cacctaatga tggtcaggga atcgttttgg aattggattc aagcgttgaa
     8221 aaacaatttg gcaatcatat cagagcatta atcaagacaa cacttgccag gctgggcgtt
     8281 gagtcagcaa cgatcgaagc tgttgataag ggagccttgg attgtaccat tcaggcaaga
     8341 acaattgcag cagtccatcg tgctgctgga gttgagcatt acaactggaa ggagatcgac
     8401 tcatggaacg cttaagaaga acgatgatgt ttgttccggg cgctaatgcg gctatgctaa
     8461 gagatgcacc cttgtttgga gcggactcta tcatgtttga tttagaggat tcagtttcct
     8521 taaaagaaaa agacacctct cgcgcccttg ttcattttgc cctaaaaacc tttgattatt
     8581 caaatgttga gacagttgtg cgcgttaata gcctagactc ttgtggtgct ctggatattg
     8641 aggcagttgt gttagcaggt gttgatgtta ttcgcttgcc aaagacagaa actgcccagg
     8701 atattattga tgttgaggca gtcattgagc gtgttgagcg tgacaatggg attgctgttg
     8761 gtcgtacacg catgatggca gctatcgagt ctgcagaagg ggtcttaaaa gctcgtgaga
     8821 ttgcaaaggc ctcaaatcgt ctcattggta ttgccctcgg cgcagaggat tatgtgacta
     8881 atatgaaaac acgtcgctac ccagatggac aagaattatt ctttgcccgc agcatgattc
     8941 ttcacgcagc acgtgctgct gggattgcag caattgatac cgtttattca gatgtcaaca
     9001 atacagaagg cttccaagct gaggtgcgtc atatcaagca attaggcttt gatggtaaat
     9061 ctgtcatcaa ccctcgtcag attccattgg taaatgagat ttatacacca accgaaaaag
     9121 agattagtca cgccaagcaa gtgatctggg ccattcgtga ggctgaaagt aagggatcag
     9181 gtgtcatttc attaaatgga aaaatggtag ataagccaat cgtagagcgt gcacagcgtg
     9241 ttatcgcttt ggcaacagct gctggggtat taacagagga ggacatttag catggttaaa
     9301 aataaacttg gtcgtgatat tcctcaggag tatgctgatc actatggagt atttgaagga
     9361 gagctagcac gtatcactag ctacaatgaa tcaagccgcc gcattaagcc tgtaaagcca
     9421 ggtgacagta aattgcttgg ctctattcgt gaagctattg aaaagacagg cctaaaagat
     9481 ggcatgacca tttcatttca ccatcatttt cgtgaggggg acttcgtcat gaatatggtt
     9541 cttgatgaga tagccagcat gggaatcaaa gatttagcta ttgctccaag ctctattgcc
     9601 aatgtgcatg agccattaat tgagcacatt aaaaacggag tggttacaag cattacctca
     9661 tcaggtttac gtgataaggt tggggcagct atttcatcag ggattatgga aaagcctgtt
     9721 gtgattcgtt ctcatggagg acgtgctcgt gcgattgcta gtggtgatat tcatattgac
     9781 gttgcctttt taggagcacc aagctcagat gaatatggta atgtcaacgg tacgattggt
     9841 aaggctacct gcggctcact tggctatgct atgatcgatg ccaagtacgc agatcaggtg
     9901 gtggtgctga cagatcacct agttgattat cctaacaccc caattagcat tccgcaaact
     9961 gatgttgatt atgtcgtgac agttgatgct attggtgatc cacaaggaat cgctaaggga
    10021 gcaacgcggt tcaccaaaaa tcctaaggag ctcctaattg ccgaatatgc cgctaaggtt
    10081 atcacacagt cgccttactt taaaaatggc ttttccttcc aaacaggtac aggaggagct
    10141 tccttagcag tgactaggtt catgcgtgag gccatgcttc aagaaaatat caaggcaagc
    10201 tttgcccttg gaggcattac aaacgctatg gtagaattgc tcgaagaagg attagttgag
    10261 aaaatcctag atgtacagga ttttgattac ccttcagcag tttcgcttgg taaaaatgct
    10321 cagcattacg aaattgatgc taacatgtat gcctcaccac taagcaaggg atcggttatc
    10381 aatcaattag acacctgtat tttatcagcg cttgaggttg acactaattt caatgttaat
    10441 gtcatgacag gttctgacgg tgttattcgt ggggcttccg gagggcattg tgacacagcc
    10501 tttgctgcca aaatgagtct ggtgatttca ccccttatcc gcggacgcat tccaaccttt
    10561 gtagatgagg taaatacagt aattacacct ggaacaagcg ttgatgtggt tgtcacagaa
    10621 ataggtattg ctatcaatcc aaaccgtcca gatttgatag agcatttcaa ggacttgaag
    10681 gttcctcaat ttagtatcga agaattaaaa gaaaaggctt actcgattgt tggaacacct
    10741 gatcgtatcc aatacggtga taaggttgta gctcttattg agtatcgtga tggcagcctg
    10801 attgacgttg tctacaatgt ctaaggaatt gattttcaag gggaaagctg ttaccctagc
    10861 tgatatgcta agggcacgcg aggacagaag ccttcgtcaa ggaaagcttt taacagaatt
    10921 ctcaaacgaa agcctgcttt ctgtgaccat gaatattcca ggccccatta aaacgtcacc
    10981 tgctttactt gaggtatttg atagtgttat caaggcaatc ctagaaaagc tgtctggcaa
    11041 tcagatcagc tatcagcttc gtttgctgcc aaaaacgggt tatgaatatt accttgtgac
    11101 agccttagat agtcaggcat taaagctcaa aatgattgag cttgagactg atttaccgat
    11161 tggcaggcta atggatttgg acgttttagt gctgacaaat cagctgccaa cccctatcag
    11221 tcgaacagcc ttaggctttc ctcctcgcag ctgctatctt tgctcaaaag aggctaaggc
    11281 ttgtagtaga aatcgcagtc actcggtagc agacatgcag acagcccttg tacacttact
    11341 ccaatcattt tttgacggag gcaatcagct cagttagact caacggtatt cttataagga
    11401 gaatgatatg acaaaaatcc gtataacaga aacagttttg cgtgatggtc agcaaagtca
    11461 aattgctacc cgcatgacta caaaggaaat gattccgatt ttagaaacac tagataatgc
    11521 tggctatcat gccctagaaa tgtggggagg agctaccttt gattcttgcc tacgtttctt
    11581 aaatgaagac ccttgggagc gtctaagaac cattcgtaaa gtagtcaaga aaactaaatt
    11641 acaaatgctc ctgcgtgggc aaaatctttt gggctatcgt aattatgctg acgatgtcgt
    11701 ccgcagcttt atccaaaaat caattgaaaa cggtattgat attgtgcgca tttttgatgc
    11761 cctaaatgat ccacgtaatc tagagacagc tgtttcagca acaaaagaat tcggtggcca
    11821 tgcacaggtt gctatttctt acacaacaag tccagttcat actatcgatt attttgtagc
    11881 cttagcaaaa gcctatcagg ctattggtgc agattcgatt tgtatcaagg atatggctgg
    11941 tgtgttaacc ccggagaccg gttatcaatt agtgaagcgt atcaaggaaa gcattgctct
    12001 accacttgag gttcacacgc atgctaccag tggtatttct gaaatgacct atctcaaggt
    12061 cgtagaggct ggtgcagata ttattgatac tgccatatcc tcatttgccg gcgggacaag
    12121 ccagccagca acagaatcga tggttattgc tttagaggac ttggggattg ataccggagt
    12181 agacatgaca aggctgacaa aaattgccga gtattttaat actatccgag atcactacag
    12241 ggcagagggc attttaaatc ccaaggttaa agacactgag cctaagacct tgctttatca
    12301 ggttcctggc ggcatgctgt ccaatttgct aagtcagctt aaggaacagg gactctctga
    12361 caaatatgaa gaggttctgg ctgaggttcc aaaggttaga gctgatttag gctacccccc
    12421 actggtgact ccgctatcgc aaatggttgg cacacaggcc ttaatgaatg ttatttcagg
    12481 tgaacgctac aaggttgtcc caaacgaaat caaagactat gtcagaggac tttatggcca
    12541 acctcctgcg ccactaggtg aaggtattaa agagaaaatc attggtgatg aagctgttat
    12601 cacttgtcgt ccagcagatt tgattgagcc acaattgccc ttgcttcgtc aagaaattgc
    12661 aggctatgcc tgctgtgagg aggatgtgct gagctatgcc tctttccctc agcaggcaaa
    12721 ggatttccta ggacgcagag aggatccctt ttatgatatc ccagttcagt acgtcaccgt
    12781 tgatatagca atggattaat caaaagaata aaaagcaaga taactaataa aatcaatctc
    12841 ctaattatta gtcaaagcta cctaccaata aactccttaa tcagaaccac ccgtctaatg
    12901 aggtgccccc aaaaggttag tccaaaactt taggctccat gtcaactgta gtgggtagtt
    12961 gacaagctaa catctggaga ggac
//
LOCUS       DARYYD010000051        12846 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.052, whole genome shotgun sequence.
ACCESSION   DARYYD010000051 DARYYD010000000
VERSION     DARYYD010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12846
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.052"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            51..917
                     /locus_tag="TV188_001538"
     CDS             51..917
                     /locus_tag="TV188_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HEL1534875.1"
                     /translation="MKSKKKFFLLSLLALSAFFLSACSSWIDKGESITAVGSTALQPL
                     VEAAADEFGSNNLGKSVNVQGGGSGTGLSQVQSGAVQVGNSDVFAEEKDGIDAAKLVD
                     HQVAVAGLAVIANPKVKVSNLTSKQLQKIFSGEYTNWKQVGGQDLAISVINRAASSGS
                     RATFDSVIMKGVTAKQSQEQDSNGMVKSIVSQTPGAISYLSFAYVDSSVKSLRLNGFK
                     ANAKNVATNDWPIWSYEHMYTKGKPDGLTKEFLDYVLSDEVQKTIVTHMGYIAITDMK
                     VVKSYDGKVTDK"
     gene            928..1863
                     /gene="pstC"
                     /locus_tag="TV188_001539"
     CDS             928..1863
                     /gene="pstC"
                     /locus_tag="TV188_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEL1534876.1"
                     /translation="MKNQELAKQLASPSKNSRLEAFGRTITFFCLALIVFIVAMILLF
                     VAQKGLSTFFVNKVNLFDFLFGTEWQPSVKNAAGVPYLGALPMIAGSFLVTILSALVA
                     TPFAIGAAVFMTEISPKYGAKLLQPAVELLVGIPSVVYGFIGLQVVVPFIRSIFGGTG
                     FGILSGVCVLFVMILPTVTFMTTDSLRAVPRHYREASMAMGATRWQTIWRVVLNAARP
                     GIFTAVIFGMARAFGEALAIQMVVGNSAVMPASLTTPAATLTSVLTMGIGNTVMGTVQ
                     NNVLWSLALVLLLMSLAFNSLVKLITKERKRNYER"
     gene            1853..2740
                     /gene="pstA"
                     /locus_tag="TV188_001540"
     CDS             1853..2740
                     /gene="pstA"
                     /locus_tag="TV188_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008088954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEL1534877.1"
                     /translation="MNAKKVDKVATGSLYTIAGIIVAILASLILFILVRGLPHISWSF
                     LTGKSSSYEAGGGIGIQLYNSFFLLVVTLIISIPLSTGAGIYLAEYAKKGPVTNVIRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLLHVH
                     HTQREAGLALGLSRWETVFHVVIPEALPSIVTGIVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNPLSVTSPISIFRQSETLAVHIWKVNSEGTIPDATLVSAGSAAVLLIFILIF
                     NLSARFIGKRIHAKMTAAK"
     gene            2757..3560
                     /gene="pstB"
                     /locus_tag="TV188_001541"
     CDS             2757..3560
                     /gene="pstB"
                     /locus_tag="TV188_001541"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1534878.1"
                     /translation="MTEYNWNERHIITFPEETIALATKDLHVYYGSKEAIKGIDMQFE
                     KNKITALIGPSGCGKSTYLRSLNRMNDTIDIARVTGEILYQGIDVNRKDMNVYEIRKH
                     LGMVFQRPNPFAKSIYKNITFAHERAGVRDKRVLDEIVETSLKQAALWDQVKDDLHKS
                     AFTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKDYTIIIV
                     THNMQQAARASDYTAFFYLGDLIEYDKTRNIFQNATCQSTNDYVSGHFG"
     gene            3574..4332
                     /gene="pstB"
                     /locus_tag="TV188_001542"
     CDS             3574..4332
                     /gene="pstB"
                     /locus_tag="TV188_001542"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEL1534879.1"
                     /translation="MAEPILQIRDLSVYYNKKKTLKDVSLDFYPNEITALIGPSGSGK
                     STLLRSINRMNDLNPEVTITGSIVYNGHNIYSPRTDTVDLRKEIGMVFQQPNPFPMSI
                     YENVVYGLRLKGIRDKAVLDHAVESSLKGASIWSEVKDRLHDSAVGLSGGQQQRVCIA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLFSLKKDYTMVIVTRSMQQASRLSDRTG
                     FFLEGDLLEFGPTKAMFMNPKRKETEDYISGKFG"
     gene            4403..5056
                     /gene="phoU"
                     /locus_tag="TV188_001543"
     CDS             4403..5056
                     /gene="phoU"
                     /locus_tag="TV188_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEL1534880.1"
                     /translation="MLRTKFEEELDKLHNQFYSMGTEVLSQINKTVRAFVSHDRELAK
                     EVIEEDDTINGFETKLEKKSLEIIALQQPVSNDLRTVITVLKASSDIERMGDHAASIA
                     KATIRMKGEERIPIVEEHINLMGKAVKQMVEEALNAYINADDAKAYEIAASDEIIDNY
                     FREIQSLAVEEIRKTPDAVFAGKEYFQVLMYLERIGDYARNICEWIVYLKTGKIIEL"
     gene            5290..7827
                     /locus_tag="TV188_001544"
     CDS             5290..7827
                     /locus_tag="TV188_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEL1534881.1"
                     /translation="MKKVEHLIEKFIPENYNIFLDINRSTKTFTGNVAINGEALDNQV
                     SFHQKDLAINAILLDNEAVSYHVDDDNELVRVELPETGMMTLVIEFSGNITDNMTGIY
                     PSYYTKDGEKQEVISTQFESHFAREAFPCIDEPEAKATFDLSLTFDQAEGEIALSNMP
                     EVNAERRKETGLWTFETTPRMSSYLLAFALGDLHGKTTKSKNGTTVGVYATKAHPLTS
                     LDFSLDIAVRVIDFYEDYFGVRYPIPQSLNIALPDFSSGAMENWGLITYREIYLLVDG
                     NSTARSRQNVALVVAHEIAHQWFGNLVTMKWWDDLWLNESFANMMEYVAINAIEPSWR
                     IFEDFQTTGVPLALKRDATDGVQSVHVAVNHPDEINTLFDPAIVYAKGSRLMHMLRRW
                     IGDKDFAAGLRLYFEKHQYRNTVGRDLWQALSEASGKDVAAFMDAWLEQPGYPVLTAR
                     VDNDQLILSQKQFFIGEASDQKRLWPIPLNANWKGLPDVLTEESIVISGFSQLAAQNK
                     GTLRFNTENTAHYITDYQGQLFHSLVDDLKHLDNTSALQVIQERRLLADSGLISYAEL
                     VDLIAQLDDKKSYMVAAAVQQVIRGLEQFIDEGTSAEQSFNRLISSIFQEDFRQLGFE
                     KRANESDEDEMVRQIALHHLLVGGNRDVIKQAKTIFEAYANRIEAIPAAIRRSVLVSQ
                     IKYFEIADLVDAYFDAYVATKDNNLRADLSAALATTANPSTLKRIQYSLKDKDIIKPQ
                     DLAAWYSFLLDQASAQESIWRWARENWKWIKASLGGDMSFDKFIIYPANHFKTAERLA
                     EYKAFFEPQLDDMAISRNISMGINEISARVALIDSEKEAIANALSQY"
     gene            8246..8920
                     /locus_tag="TV188_001545"
     CDS             8246..8920
                     /locus_tag="TV188_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1534882.1"
                     /translation="MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGI
                     YDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTAKESIDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQAIELLGKELDLLIY
                     ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGY
                     ILKANE"
     gene            8913..10223
                     /locus_tag="TV188_001546"
     CDS             8913..10223
                     /locus_tag="TV188_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEL1534883.1"
                     /translation="MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYS
                     TVDSSLISVSQNASNYANRTMARISSFYFDAENNLIQALPELEASKSLGSSTTNMDII
                     LFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
                     PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAK
                     QKMFVENASHELRTPLAVLQNRLESLFRKPNETILDNSEHIASSLDEVRNMRILTTNL
                     LNLARSDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISVNQINRPLKTDKALLK
                     QLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVD
                     KARARQKGGFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL"
     gene            10608..11027
                     /locus_tag="TV188_001547"
     CDS             10608..11027
                     /locus_tag="TV188_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534884.1"
                     /translation="MIVYLKQHKNYWKLVSIAALIIILGGILTMNWLNGEELKKKKYR
                     QEQDRVVKYIGEHIELCNGQPITKIEFIEFQLETATTGTWSITTIVNEKYLIHFSEDR
                     LGEEIRTSYYSPKEFKQYSEKMRNNMTNVETIYYEEK"
     gene            11024..12217
                     /locus_tag="TV188_001548"
     CDS             11024..12217
                     /locus_tag="TV188_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534885.1"
                     /translation="MMIDRDYKNISEDVYKVDSGKERDPIQEGYPVANGKYRVLEAED
                     NPDNGMQAMAVVPIKDGKEDRSHIVIAYAGTNSSDIRDIDTDIQSVVFGDDQYLCTHE
                     EPDSFKVVKSQLSTAKAFSDYIRTSYPNAAISYTGHSLGGYLALITAAHAKQPATVFN
                     APSSVNNLSKEAIDFVKANKGLYHSYRINNDYIGNLGTYFGDDELGISRWVDGKAGIG
                     RHSLAAYRFNSKGQVIDRKGRPAAAQAPALATLSSKLTEYRLLKKKYVASNGISSSEE
                     FYLDQFQARAVAQALEQTTQLAQEEIIARRKEAVAEAEALHQKTRDMPFFVSELSWAE
                     LEEAYAQAGVTYDSLVGQTKRHFDDKVTQARGLATKFKTVKEQLEEGVERTAAIDQKL
                     GCDFS"
     gene            12214..12606
                     /locus_tag="TV188_001549"
     CDS             12214..12606
                     /locus_tag="TV188_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534886.1"
                     /translation="MTALEKIRTAIRQKEEELEEQQEHYHQERLQMAAAHDELRGNYN
                     QLQQLYASSYQAVSSYLRHYDASLITDQYTVLTRLIDDYQHRTEQCYHEQGRKMSQQE
                     EAIDHHYRSQRQAIEKDITALRRQWREG"
     gene            12626..>12846
                     /locus_tag="TV188_001550"
     CDS             12626..>12846
                     /locus_tag="TV188_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534887.1"
                     /translation="MIAIEMILTGQEPIRTLKKELDRRLVQSICAPLTLGRLHALQRR
                     YDSEVSRIATDTADHIQTIVNQLDSSIRG"
BASE COUNT         3817 a         2422 c         2874 g         3733 t
ORIGIN      
        1 agcttaattc ttcgctataa acctttattt ttatgaatag gaatagaata atgaaatcga
       61 aaaagaaatt ctttttgtta agtcttttag ccttgtcggc tttctttttg tcagcctgct
      121 caagctggat tgataaggga gaatccataa cagcggtagg ctcaacagca ttacagccct
      181 tagtagaagc cgcagctgat gagtttggaa gcaataacct cggaaaatct gttaatgttc
      241 aaggaggcgg ctctggcact ggcttatcac aggtgcagtc aggtgctgtt caggtaggca
      301 atagtgatgt ctttgcagaa gaaaaggacg ggattgatgc tgctaagctt gttgatcacc
      361 aggttgccgt agcaggactt gctgtcattg ccaatcctaa ggtcaaggta tctaatctca
      421 caagcaagca gctacaaaag attttctcag gtgaatatac caactggaag caggttggtg
      481 gacaggatct tgctatttca gtgattaatc gagcggcaag ctcaggctca cgtgctacct
      541 ttgatagtgt catcatgaag ggtgttactg ctaagcaaag tcaagagcag gattctaacg
      601 gtatggttaa atcaattgtg tctcagacac cgggggccat ttcttactta tcctttgcct
      661 atgtggattc gtctgtaaaa tcattacgat tgaatggctt taaggccaat gccaaaaatg
      721 tagcaaccaa tgattggccc atctggtcct atgagcatat gtataccaaa ggcaagccag
      781 acggcttaac caaggaattt ttggattatg tgctatcaga tgaggtccaa aaaaccattg
      841 tgacacatat gggttatatt gctatcactg atatgaaggt cgtcaaatcc tatgatggaa
      901 aagttacaga taaataatgg gggaattatg aaaaatcagg aattagctaa gcaattagcc
      961 tcaccatcaa aaaattcacg acttgaagca tttggtcgta cgattacctt tttttgcctc
     1021 gccttaattg tttttatcgt tgcaatgatt ttactttttg tggctcaaaa gggcttgtct
     1081 accttttttg taaacaaggt taatcttttt gatttcctat ttggtacaga gtggcagcct
     1141 agcgttaaaa atgctgccgg tgttccttat cttggagctc ttccgatgat tgctggatcg
     1201 tttttagtca cgattttatc agccttggtg gcaacaccat ttgccattgg ggcagcagta
     1261 tttatgactg aaatttcacc caagtacggg gcaaaactat tacagccagc agttgaattg
     1321 cttgtaggta tcccgtcagt tgtttatggc tttattggct tgcaggttgt tgttcctttt
     1381 attcgttcta tttttggtgg aacaggcttt ggtatcctat caggggtctg tgtcttgttt
     1441 gtcatgattt taccgacggt tacctttatg acaacagata gtctgcgcgc tgttcctcgt
     1501 cattatcgtg aggcttctat ggctatgggg gctacacgtt ggcaaaccat ttggcgagtg
     1561 gttttaaatg cggctcgtcc tggtattttt actgctgtta tttttggtat ggctagagcc
     1621 tttggtgagg ccttagccat tcaaatggtt gtgggaaatt cagcagtcat gccggcttca
     1681 ctaaccactc cagcggctac attgacctct gtattgacta tgggaattgg taatacagtt
     1741 atgggaactg ttcaaaataa tgtgctatgg tcattagccc ttgtcttatt gctgatgagt
     1801 ctagctttta attcccttgt caaattaatt acgaaagaga gaaagagaaa ttatgaacgc
     1861 taaaaaggtt gataaagtag caactggtag cttgtatact attgctggaa ttattgtagc
     1921 tattttagct tccctaattc tgtttattct tgtgcgtggc ctacctcaca tcagctggtc
     1981 gtttttaaca gggaaatcat cgtcctatga agctggtgga ggtattggga ttcagcttta
     2041 taattcattt ttcttgctgg tagtaacctt gattatttcc attcccctat caacaggtgc
     2101 tggcatttat ttggccgaat acgctaaaaa aggacctgtg acaaatgtga ttagaacctg
     2161 tattgaaatc ctatcctcat tgccatctgt tgtggttgga ttgtttggct accttatttt
     2221 tgttgtacag tttgaatatg gcttttctat tatatcaggt gcccttgctt tgacggtatt
     2281 taatcttccg caaatgacaa gaaacgttga ggatagcttg ctgcatgtgc atcatactca
     2341 aagagaggca gggctagccc ttgggctttc acgctgggaa acggtttttc atgtggttat
     2401 tccagaggcc ttgccaagta ttgtgacagg tattgttttg gcttcaggtc gtatctttgg
     2461 tgaagcagct gctcttatct atactgcggg tcagtctgcc ccagcgcttg attggtcaaa
     2521 ttggaaccct ttgagcgtga caagccctat ttcaattttc cgtcaatctg aaaccctagc
     2581 tgttcatatt tggaaggtca atagtgaagg gacaatccct gatgcaacac ttgtttctgc
     2641 tggtagtgca gcggtgttgt tgatttttat ccttattttc aatctatcag ctcgctttat
     2701 tggcaagcgt attcatgcta agatgacagc agcaaaataa gacattggag agattcatga
     2761 cagaatataa ttggaacgaa cgtcatatca ttacatttcc agaagaaacg attgccctag
     2821 ctactaagga tctgcatgtt tattatggta gcaaggaggc aatcaagggg attgatatgc
     2881 aattcgaaaa aaataaaatt acagccctaa ttggaccctc aggctgtggc aagtcaacct
     2941 atctgcgcag cctcaatcgc atgaatgaca ccattgatat tgctagagta acaggtgaaa
     3001 ttttgtatca aggcattgat gtcaatcgaa aggacatgaa tgtgtatgaa atccgtaagc
     3061 acctaggaat ggtctttcaa aggccaaatc catttgccaa gtctatttat aaaaacatca
     3121 cctttgctca tgaaagagca ggagtgagag ataaaagggt tttagatgag attgtcgaaa
     3181 cctccctcaa gcaggctgca ctatgggatc aggtcaagga cgatcttcat aaatcagcct
     3241 ttaccctttc aggaggtcag cagcagcgct tgtgtattgc tagggctatt tcggttaagc
     3301 cggatatctt gttgatggac gaaccagctt cagcccttga tcctattgca accatgcagc
     3361 tagaagaaac catgtttgag ttgaagaagg attacaccat tattatcgtt actcataaca
     3421 tgcagcaggc cgctagagca agtgattaca ctgctttctt ctatttgggt gacttaattg
     3481 aatacgataa aacgcgtaac attttccaaa acgctacctg tcagtccaca aatgattacg
     3541 tctcagggca ctttggttag aaagaaggat atgatggcag aacctatttt acaaatcaga
     3601 gatctttctg tttactataa taaaaagaaa accttaaagg acgtgtcctt agatttttac
     3661 ccaaatgaaa tcacagcact cattggccct tcagggtctg ggaaatcaac acttttgcgt
     3721 tccatcaatc gcatgaatga cctgaatcca gaggtaacca ttacggggtc aatcgtttat
     3781 aatggacata acatttacag tccaagaaca gacactgttg atttgcgaaa agaaattggt
     3841 atggtctttc agcagcccaa tccctttcca atgtctatct atgaaaacgt tgtctatggc
     3901 ttgcgcctaa agggcattag agataaggct gttttagatc acgctgttga atcctctctc
     3961 aaaggagcct ccatctggag tgaggtcaag gataggcttc atgattcagc tgttggacta
     4021 tcaggaggtc aacagcagcg tgtctgcata gcaagggttc tggcaaccag ccctaaaatc
     4081 attttgttag atgagccaac atcggcttta gatcccattt cagccggcaa aatcgaagag
     4141 accctgttct cactaaaaaa ggattatacg atggttatcg ttacccgctc catgcagcag
     4201 gcctcgcgct tgtcagaccg gacaggcttc ttcttagagg gagaccttct tgagtttggt
     4261 cctactaagg caatgtttat gaaccctaag aggaaggaaa cagaagatta tatttcgggt
     4321 aaatttggct aagggatctt gtttgtagtc taggtatccg ctctgtttag gataataaat
     4381 gaatcaatag aaagaaaaaa tgatgttaag aactaaattt gaagaagaat tagacaagct
     4441 acacaatcag ttttactcta tgggaacaga agtcttgtct caaatcaata aaaccgttcg
     4501 tgcctttgtc agtcatgacc gcgaattggc caaagaggtg attgaggaag acgataccat
     4561 caatggattt gaaacaaaat tagaaaaaaa gtctcttgaa attatcgcct tacagcagcc
     4621 tgtttcaaac gatttgcgaa cagttattac tgttttgaag gcctcaagtg atattgagcg
     4681 tatgggagat cacgctgcct ctatcgctaa agcaaccatt cgcatgaaag gagaagagcg
     4741 tatcccgatt gttgaggagc atatcaactt gatggggaag gcagtcaagc agatggttga
     4801 agaggcgcta aatgcttata ttaatgcaga tgatgccaag gcctatgaaa ttgctgcttc
     4861 agacgaaatc attgataatt atttccgcga aatccaatct ctagctgtcg aagaaattcg
     4921 caagacacca gatgccgtct ttgctggcaa ggaatacttc caggttctca tgtatttaga
     4981 gcgtatcggt gactatgctc gtaatatttg tgaatggatt gtctatttaa aaactggaaa
     5041 aattattgaa ttataagaaa gtatggtata atgggggctg ggtgaacttc tcagttcctc
     5101 gttttattat agcgattaaa aggttttaga ggctggagct tcagctgagc tgactatcag
     5161 ctgtcaagct tctagacaaa atgaaagata acaataagct agtcgtctaa gggactagac
     5221 ggcaggattg attatattaa gaatgtgacc ttgtcccatc actaatttaa tgacatatta
     5281 aggagttgta tgaaaaaagt agaacatctt attgaaaagt ttattcctga aaattataat
     5341 attttcttag acattaatcg cagcacaaaa accttcacag gtaatgttgc aatcaatggt
     5401 gaagcattag ataatcaagt gtcatttcac caaaaggact tggcaatcaa tgccatttta
     5461 cttgacaatg aagctgttag ctatcatgtt gacgatgaca atgagcttgt gcgtgttgag
     5521 ctgccagaga ctggtatgat gacgcttgtc attgaatttt caggtaatat tactgacaat
     5581 atgactggta tttacccgtc ctattacaca aaagatggtg aaaaacagga ggttatttca
     5641 acgcagtttg aaagccattt tgcgcgtgag gcctttccat gtattgacga gcctgaagca
     5701 aaggctacct ttgacttaag cttgacattt gaccaagcag agggcgagat tgctctatca
     5761 aatatgcctg aggtcaatgc tgagcgccgc aaggagaccg gtctttggac ctttgagaca
     5821 actcctagaa tgtcttctta tctgctggcc tttgccttag gagacttgca tggcaaaaca
     5881 acaaaaagta aaaacgggac aacagttggt gtttatgcaa ccaaggctca cccactgacc
     5941 tcgctagatt tttcattgga tattgctgta cgtgtcattg atttttacga agactacttt
     6001 ggggttcgct atcctattcc gcaatctcta aatattgctc ttcctgattt ttcatctgga
     6061 gcgatggaaa actggggctt gattacctat cgtgaaattt acctgttggt tgatggcaat
     6121 tcaacagccc gcagcagaca aaatgttgct cttgttgtgg cacacgagat tgcccatcaa
     6181 tggtttggta atcttgtaac catgaaatgg tgggacgatc tttggctaaa tgaaagcttt
     6241 gccaatatga tggaatatgt agccatcaat gctattgagc cgtcatggcg tatttttgag
     6301 gatttccaaa caacaggtgt gccgctggct cttaagcgtg atgcaacaga cggtgttcaa
     6361 tcagtccatg ttgctgttaa tcacccagat gagattaata ccctgtttga tccagctatt
     6421 gtctatgcca aaggtagccg cttaatgcat atgcttcgtc gctggattgg cgataaggat
     6481 tttgcggcag gtctgcgcct ttactttgaa aagcatcaat accgtaatac tgtaggacgt
     6541 gatttgtggc aggctctttc agaagcttct ggtaaagatg ttgctgcgtt tatggacgct
     6601 tggctagagc agccaggcta tcctgtctta acggccagag ttgacaatga tcagttgatt
     6661 ctcagccaaa agcagttctt tattggtgag gcaagcgacc aaaagagact atggccaatt
     6721 ccactaaatg cgaactggaa aggtcttcct gacgtactga cagaggagtc catcgttatt
     6781 tcaggcttta gtcaattagc cgcccaaaat aaaggaacac ttcgctttaa tacagaaaat
     6841 acagcgcatt acattacaga ttatcaggga cagctctttc atagcttagt tgatgatttg
     6901 aagcatcttg acaacacctc tgcccttcaa gtgattcaag agcgccgctt gctggctgat
     6961 agcggtctga tttcttatgc agagctggtt gacttaatcg ctcagctaga tgacaaaaaa
     7021 tcctatatgg ttgctgcagc tgttcagcag gttattagag gcttagagca gttcattgat
     7081 gaaggaacct cagcagagca gtccttcaat cgattgattt cttctatttt ccaagaggac
     7141 ttcaggcagc ttggatttga aaagagggca aatgaatctg atgaagatga aatggttcgt
     7201 caaattgctt tacatcacct gttggttgga ggcaatcgtg atgtgatcaa gcaggccaag
     7261 actatctttg aagcttatgc aaatcgtatc gaagccattc cagcagccat tcgccgctcg
     7321 gtattggtga gtcagatcaa gtattttgaa atagctgact tggttgatgc ttattttgat
     7381 gcttatgttg caaccaagga caacaatctt cgagctgatt tgagcgccgc cttagcaaca
     7441 acagctaatc catcaactct taagcgcatt cagtacagct taaaggataa ggatattatt
     7501 aagccacagg acttagcagc ttggtacagc tttttgcttg atcaggcctc tgcacaagaa
     7561 agcatttggc gttgggctag agaaaattgg aagtggatta aggcttcact gggtggtgat
     7621 atgagctttg acaagtttat tatttaccct gctaaccatt ttaaaacagc agagcgttta
     7681 gctgaatata aggccttctt tgagccacag cttgatgata tggcgattag tcgcaatatt
     7741 tcgatgggga taaatgaaat ttcagctcga gttgccctca ttgatagtga aaaggaagct
     7801 atcgctaatg ctttaagtca gtactaatga tatcacaaag gagctgggga ccatcctcaa
     7861 ctcctttatt ggtgtcaaag ctactatctt taagtaacat ttagatcaaa gggtaattgc
     7921 tgtagcttag tggcactgcc tgtcagcttt tggcaaatga ggaggcttca atcataagca
     7981 gtggttaatc ttagcgccgt aaattactag ttgatcagag tcagagctta ggacggatag
     8041 gtcatagaga caattctttg tctgtcagtt ttataactta agtaggtctc cagactaact
     8101 gtatgcttat gacctgtcat gagcaatagt ttagcaaagc ttaagctttt tgtgttatcg
     8161 ttagattaga gaattcattt agtaaggtaa tccctaaaga ctacttgagc gaggctgtta
     8221 gtctttagag aattgaggta tcataatgat aaaactatta ttagtagaag acgatttaag
     8281 cttgtcaaat tctatctttg attttttaga tgactttgct gatgtgacgc aggtttttga
     8341 tggtgacgaa ggactctatg aggcagaaag cggtatttat gatttgattc tgttagattt
     8401 gatgctgcct gaaaaggatg gctttcaagt gttaaaagcc ttacgtgaaa aagacatcaa
     8461 aattcccgtc ttgatcatga ctgccaaaga aagcatcgat gacaaagggc atggctttga
     8521 gcttggtgct gatgactatt taaccaagcc cttttaccta gaagaattaa aaatgcggat
     8581 tcaggccttg cttaagcgcg taggaaagtt taatgacaag agccttaaat ttggcaacct
     8641 gactgtagat actacccgta aagaggtaca ggtcaatggg caggccatag agctattagg
     8701 caaggagctt gatttactaa tctatatcct tcaaaatcaa aatgttattt tgccaaaatc
     8761 acaaattttt gatcgtatct ggggctttga tagtgatacc actatctctg ttgtagaggt
     8821 ctatgtctct aaaattcgta agaagcttaa ggggacagac tttgttaatc atcttcaaac
     8881 cttgagaagt gtaggatata tcttaaaagc taatgaataa actaaaaaaa ggattattgt
     8941 ccgataatta tacgcatttt tttcatttct ttgctatttt tacaggcatt tttgttgtca
     9001 tgaccatcat tattttacaa atcatgaggt ttagtgtcta ttccacagta gacagcagtc
     9061 tcatttcggt cagtcaaaat gccagcaact atgctaatag gaccatggcg agaatatctt
     9121 ccttttattt tgatgcagaa aataacctta ttcaggctct tcctgaactg gaagcgtcaa
     9181 aatcacttgg ctcctccacc actaatatgg atattatttt atttagtgct aatgggacga
     9241 tattgaactc ctttgacgct ttctctaatt accaaagctt tcgtttagac aaaagccagc
     9301 tcaataacat tgtcaccaca cagctgatga atttttatgg gcaaaaggag aaataccata
     9361 ccctaaccgt taaggttcac attaaaaact atccagcagt ggcttatatg atggcagtgg
     9421 ttaatgttca gcagctggat actgctaatg agcgctatga acagattatt atcatggtta
     9481 tgattgtctt ttggttaatt tcgattttgg ccagtattta tttggctaag tggagcagaa
     9541 agccaattat ggagagctat gccaagcaaa aaatgtttgt agaaaatgcc agtcatgagc
     9601 ttaggactcc tttagcggtg ctgcaaaatc gtttggaatc gctgtttaga aagcctaacg
     9661 aaaccatttt agacaatagc gagcatattg cgtcaagcct agatgaggtt cgtaatatga
     9721 gaatattaac aactaatctg ttaaatttag ccagaagtga tgatgggatc aagccgcagc
     9781 tagttgatgt tgatgcagcc ttttttgata ctgtttttga aaattatcaa ttagttgcag
     9841 aagagtcagg caagcagttt atctcagtta atcagatcaa taggccctta aagacggata
     9901 aggctttgct caagcagctg atgaccattt tgtttgataa tgcgatcaaa tacactgatc
     9961 ataacggtgt ggttgaggtc aaggttagaa cgaccgataa gcatttattg atttctgtta
    10021 ttgataatgg cccagggatc aaggatgatg ataagaaaaa gatttttgat cgcttttacc
    10081 gagtggataa ggcaagggca cgccaaaaag gagggtttgg actcggattg gccttagcgc
    10141 agcagatcgt tacctcatta aaaggaacga ttaccgtcag tgataataag cctaccggcg
    10201 ccatctttga agtaaaatta tagcactgag ttcttgctag cccataatca gtatgaaaat
    10261 aacagtcact agatcaagaa gtctagtgac tttttttatt gtcttctttt tgctgttgac
    10321 caagcagttg acaagaaaat tccaatagat agtttaaagc caataaaacc attattaggc
    10381 ttgcattaca ggcaggtatc aaacaaagat atagaaaaat ataccataaa aaatctcata
    10441 aaagtgtcaa aatggtaaaa aattgccaac aatatgtcga tattatacca ttattatagt
    10501 ataatattta taatcgtatc ataatattaa aatatctggt gtctagctgt ttttgtaaaa
    10561 gcaaaaaact tgcaacacct tatgataaag cataaaggaa tacaagcatg atagtctacc
    10621 taaagcaaca caaaaattac tggaaattag tcagcatagc cgctttaatc attattttag
    10681 gaggaatact aacaatgaat tggcttaatg gcgaagagct aaaaaagaaa aagtacagac
    10741 aagagcagga tagggtagtg aaatacatag gagagcatat agagctatgt aatggtcagc
    10801 ctataacaaa aattgagttt atagaatttc agttagaaac tgcaaccacc ggaacttggt
    10861 caataacaac aattgttaat gagaaatatc tgattcattt ttcagaagat agattaggtg
    10921 aagaaatacg gacttcctat tattctccaa aagaatttaa gcaatacagt gaaaagatga
    10981 ggaataatat gactaatgtt gaaacaattt attacgagga gaaatgatga ttgatagaga
    11041 ttataaaaat atttcagagg atgtgtataa ggttgattct ggtaaagaaa gagatccgat
    11101 tcaagaagga tatccggttg ccaatggaaa ataccgcgtt cttgaagccg aagataaccc
    11161 cgacaatggt atgcaggcta tggctgttgt gccaataaaa gatggcaaag aggatagaag
    11221 tcatatcgtc attgcctatg ccgggacaaa tagcagtgat atacgcgata ttgacaccga
    11281 tattcaatcc gttgtttttg gagatgatca atacctgtgt acccatgagg agcctgattc
    11341 ttttaaagtg gtcaagagtc agctaagtac tgctaaagcc ttttccgact acattaggac
    11401 aagctaccct aacgctgcca tctcctacac cggacactct ctgggaggct atctggcact
    11461 catcacagct gcccatgcca agcagcctgc cactgtcttt aatgcgccaa gctctgttaa
    11521 taacctctcc aaggaggcta ttgactttgt taaagccaac aagggactct accacagcta
    11581 ccgcattaac aatgactaca ttggaaatct gggcacttac tttggagatg atgagctagg
    11641 gatttcaaga tgggttgacg gtaaggcggg aataggacgt catagcttag ccgcttatcg
    11701 cttcaactca aagggtcagg tgattgaccg taagggtcgt cctgccgctg ctcaagcacc
    11761 tgctcttgct accctaagct caaagctaac cgaataccgc ctgctaaaga aaaagtatgt
    11821 agcctctaac ggtattagca gctcagagga gttttacctt gatcagtttc aggctcgagc
    11881 agtcgcacag gctttggagc agaccactca gcttgcccaa gaggagatca ttgctcgccg
    11941 gaaggaggcg gttgcagagg cagaggcact tcaccaaaag acaagagaca tgcccttttt
    12001 tgtgagtgaa ttgagctggg cggagctaga ggaggcttat gcccaggcag gagtgaccta
    12061 tgacagcctt gtgggtcaga ccaagaggca ttttgatgac aaggttactc aagctagagg
    12121 actggccaca aagttcaaga ccgtaaagga gcagctagag gagggggttg agagaacagc
    12181 tgctattgat caaaagctag gatgcgactt ttcatgacag cattagaaaa gatcagaact
    12241 gctatccgtc aaaaggaaga ggagctagag gagcagcagg agcactatca tcaagagcgg
    12301 ctccaaatgg cagcagccca tgacgagtta agaggcaact ataaccagct acagcagctc
    12361 tatgcctcta gctatcaggc cgttagcagc tacctcagac attatgatgc tagtctgata
    12421 acagaccaat ataccgttct aacgaggctg attgatgact accagcaccg aacagagcag
    12481 tgctatcatg agcaaggtcg caagatgtcg cagcaggagg aagcaattga ccatcactat
    12541 cgcagccagc gacaggcgat agaaaaggac atcacagcgc tgaggcgtca gtggcgtgaa
    12601 ggttaaggaa aaggagataa gaaagatgat tgctatagag atgatcttaa ccggacaaga
    12661 gccgatcagg actttaaaga aagagctgga taggagatta gttcagtcca tatgtgctcc
    12721 cttgacctta ggtcgccttc atgcccttca aaggcgctat gacagtgagg tatctcggat
    12781 tgccacagac accgcagatc atattcagac cattgtcaat cagctagata gcagcattag
    12841 agggca
//
LOCUS       DARYYD010000052        12843 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.053, whole genome shotgun sequence.
ACCESSION   DARYYD010000052 DARYYD010000000
VERSION     DARYYD010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12843
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.053"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(56..1075)
                     /locus_tag="TV188_001551"
     CDS             complement(56..1075)
                     /locus_tag="TV188_001551"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEL1534888.1"
                     /translation="MPKQKVAILGPGSWGTALAQVLNDNGHEVRLWGNIPEQINEINT
                     RHTNSHYFKDIVLDEAIKATLDLKEALADIDAILFVVPTKVTRLVAKQVAQVLDHKAI
                     VMHASKGLEPGTHERLSTILEEEIPAQLRSEVVVVSGPSHAEETIVRDITLITAASKD
                     ITAARYVQTLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGYGDNAKAAVI
                     TRGLAEITRLGVKLGADPLTYSGLSGVGDLIVTGTSVHSRNWRAGAALGRGEKLKDIE
                     NNMGMVIEGISTTKVAYEIAQELGVYMPITSAIYKSIYEGADIKESILGMMSNEFRSE
                     NEWHT"
     gene            1285..1734
                     /locus_tag="TV188_001552"
     CDS             1285..1734
                     /locus_tag="TV188_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEL1534889.1"
                     /translation="MPRIIAELRELTHQVEQISEEIAKKYDLQHLAGPQGHVLVFLHC
                     HQDRDIFVKDIEKELQISKSVTSNLVKRMEKNGFIRVVASATDKRCKQVVLTSAGRAK
                     LPVLKECRRDIERYFFKEISREELLTVKKVIDQLKQNIRAYKGDTDA"
     gene            1727..3436
                     /locus_tag="TV188_001553"
     CDS             1727..3436
                     /locus_tag="TV188_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003045509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534890.1"
                     /translation="MLRNAVMKYKWYAALSLVMISGVVASALLQPHYLKDVLAAIMEN
                     DQTRIAEVGFWLLVIAGIGLVSGAVNTILSAKIAQGVSADIREQTFRKIQSFSYANVE
                     AFNAGNLVVRMTNDINQIQNFVMMLFQILLRLPILFVGAFILAVQALPSLWWVLVLVV
                     VMTMVVIGLVMSQMGPRFGIFQRLMDRINQIAKENLRGVRVVKSFVQEKSQYDTFKEA
                     SNDLLGLNLFIGYGFSIMQPILMLVSYMAIYLSLYLVSGLVKTDPAVIGNMASFMTYM
                     GQISFAITMVGFMGMQASRALTSIGRIREILETEPAMTFVNHEQEELTGSIVFDDVSF
                     TYPNDSEATLKHISFEVEPGQMVGIVGATGAGKSTLAQLIPRLFDPQEGQILIGGKAL
                     PSISQETLRDTVSIVLQKAILFSGTIADNLRQGNPYADQLALENAARIAQAKEFIDRM
                     DAGYQSEVEERGNNFSGGQKQRMSIARGVINNPKILVLDDSTSALDAKSEKLVQEALN
                     KELKETTTVIIAQKISSVVKADKILVLDNGRLIGEGTHAELVASNPIYREIYETQKGR
                     EEN"
     gene            3436..5232
                     /locus_tag="TV188_001554"
     CDS             3436..5232
                     /locus_tag="TV188_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534891.1"
                     /translation="MKILRFFWFYFKRYKLSFVVIFFAIVLATYLQVKAPVFLGDSLA
                     ELGEWVQRYYKAQALSKMTGQPLVEPSMAPFRTVMGKLLLAYLFTAVANLIYSLLFTR
                     VISHSTNRMRKGLFGKLERLTVGFFDSHKDGAILSRFTSDLDNIQNSMNQSLIQVLTN
                     IALYIGLVLMMFRQDSRLALVTIASTPVALILLVVIITMARKYTDLQQKEVSALNAYM
                     DEKISGQKAIIVQGVQQDAIDGFIEHNERVRAATFKGRLFAGLLFPVMNGMSLLNTAI
                     VIFAGSTIVLGDKSMSTAAALGLVVTFVQYSQQYYQPIMQIASSWGELQLAFTGAGRI
                     QEMFDEKEEVRPEHAPVFTALKEGVEIKHVDFGYLPGQKILSDVSISASKGKMVAVVG
                     PTGSGKTTIMNLINRFYDVDAGSITFDGRDIREYDLDSLRQRVGIVLQESVLFSGTIA
                     DNIRFGNQTISQKEVETAARATHIHEFIMSLPDGYQTQVSDDENVFSTGQKQLISIAR
                     TLLTDPQVLILDEATSNVDTVTESKIQKAMEAIVAGRTSFVIAHRLKTILNADEIIVL
                     KDGKVIEQGSHHELLRQKGFYAELYHNQFVFE"
     gene            5394..6161
                     /locus_tag="TV188_001555"
     CDS             5394..6161
                     /locus_tag="TV188_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HEL1534892.1"
                     /translation="MIDLQEILARMNPNQKINYDRVMQQMTKVWARESIRPRILMHVC
                     CAPCSTYTLEYLTQYADITVYFANSNIHPKDEYHRRAYVTQKFVAEFNDKTGNSVQFI
                     EADYVPNEFVKTVRGLEKESEGGDRCRVCFDYRLDKTAQKAVELGFDYFASALTISPH
                     KNSQTINDVGIDVQKVYTTKYLPSDFKKNNGYRRSVEMCEEYDIYRQCYCGCVYAANI
                     QGIDLVQVKKDAKAFMADKDLEADFPRIRFSYAGKEI"
     gene            6363..6809
                     /locus_tag="TV188_001556"
     CDS             6363..6809
                     /locus_tag="TV188_001556"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEL1534893.1"
                     /translation="MTRIRGFELVSGFTDTDLLPKRETAHAAGYDLSVAEETSIAPGE
                     IVLVPTGVKAYMQDGEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPANEGHIFAQ
                     MKNITDQTITLSAGERIVQGVFMPFLIADGDQAGGERTGGFGSTGG"
     gene            6876..8237
                     /gene="radA"
                     /locus_tag="TV188_001557"
     CDS             6876..8237
                     /gene="radA"
                     /locus_tag="TV188_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEL1534894.1"
                     /translation="MAKKKARFICGECGYQSPKYLGRCPNCSAWSSFVEETEVKDVKN
                     ARISLTGEKSKPIKLKHINGVRYQRIQTEMNEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSIQLADKGTVLYVSGEESAEQIKMRSDRLGQTDNDFYLYAETNMQAIRAEIE
                     AIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELLQLAKSNHIATFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFDMQSGGLVEVLNP
                     SQVFLEERLDGATGSAVVVTMEGSRPILAEVQALVTPTVFGNARRTTTGLDFNRVSLI
                     MAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTNPQEAFLGE
                     IGLTGDIRRVTRIEQRINEAAKLGFTKLYAPKSSLQGIDLPKGIEVVGVTTVGEVLKA
                     VFT"
     gene            complement(8398..8676)
                     /locus_tag="TV188_001558"
     CDS             complement(8398..8676)
                     /locus_tag="TV188_001558"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534895.1"
                     /translation="MKQTKIICLLAAAAVLTLGPISTGQTQPQTVYASQVSGDSCIDL
                     GNGWFKCPKDIGGWDILFNQDYQAPSRSPFFTWISGWFNFIWQWFKSF"
     gene            9059..9565
                     /locus_tag="TV188_001559"
     CDS             9059..9565
                     /locus_tag="TV188_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEL1534896.1"
                     /translation="MSYFERFLSANEAYVALHGTAHLPLKPKTKVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRITDDMLRSLVISQQQLGTREIVVLHHTDCGAQTFTNEAF
                     TAQLHDTLGVDVSDCDFLPFTDVEASVREDMAILQQSPLIPKDVVISGAVYDVATGRM
                     SQVAMPKS"
     gene            9693..10406
                     /locus_tag="TV188_001560"
     CDS             9693..10406
                     /locus_tag="TV188_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00266 family protein"
                     /protein_id="HEL1534897.1"
                     /translation="MAYNRMTYTIDSSMQFPLVEIDLDMGESVFLQKGSMVYHTPSIS
                     LNTKLNGRGSGLGKLVGAIGRSMVSGESMFITQAIANDVSGKLALAPSMPGQVIALEL
                     GVDQYRLNDGAFLALDGSAHYTMKRQKLGKALFSGQGGFFVMSTQGEGTLLVNAFGSI
                     KKITLHGDSMTIDNSHVVAWSQDLDYDIHLENGFMQSIGTGEGVVNTFSGYGDVYVQS
                     LNLQQFAGVLQSYIVTGGH"
     gene            11008..12453
                     /locus_tag="TV188_001561"
     CDS             11008..12453
                     /locus_tag="TV188_001561"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEL1534898.1"
                     /translation="MSKPIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGDFIIRIE
                     DTDRKRHVEDGERSQLENLKWLGIDWDESPETHERYRQSERLALYQQYIDQLLAEGKA
                     YKSYVTEEELAAERERQEAAGETPRYVNEYLGMSAYEKAAYIAEREAAGIVPTVRLAV
                     NEAGVYKWTDMVKGDIVFEGGNVGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPVFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYM
                     PEAVFNFIALLGWNPGGEAEIFSREQLIALFDEIRLSKSPAAFDQKKMDWMSNEYFKH
                     ADLGAVYALCKPFLEAAGRLTEKAEKLVELYQPQLSSADEIVPLTDLFFSDFPELTAK
                     EKEVMAAETVPTVLKAFKEKLEAMSDEDFKPENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPNTIYLLGREQSIEHIANML"
BASE COUNT         3366 a         2509 c         3221 g         3747 t
ORIGIN      
        1 tgggataatg gcttttctga cctttgtcat gagttcctcc ttgatttgtg gttccttatg
       61 tgtgccattc attttctgag cgaaattcat ttgacatcat gcccagaatg ctttctttaa
      121 tgtcagcacc ttcatagata gatttgtaaa tcgcgctggt aattggcata taaaccccta
      181 gctcttgggc aatttcgtag gctaccttgg ttgtggaaat gccttcaatc accatgccca
      241 tattgttttc gatgtccttg agcttttcgc cgcgaccaag agcagcacca gctcgccagt
      301 tgcgtgaatg cacagatgtt cctgtgacaa tcaaatcacc aacaccagat aggccgctat
      361 aggtcagagg gtctgcccca agcttgaccc ctagtcgtgt gatttccgca agaccgcgtg
      421 tgatgacagc agccttggca ttgtcaccat agccaaggcc atgcagagca ccggctccaa
      481 cagcaatgat gttcttgaga gcgccagcgg tttcaacacc gatcacatca gtattggtgt
      541 agagacggaa gtagtggttg ctaaagaggg tctgaacata cctagcagct gtgatgtcct
      601 ttgaggctgc agtgattagg gtaatgtcac gaacgatggt ctcctcggca tggctaggcc
      661 cagacacaac cacgacctca ctgcgcagct gggcagggat ctcctcttcg aggatcgttg
      721 agaggcgctc atgggttcca ggctctaatc cctttgaggc gtgcatgaca atagccttgt
      781 ggtctaggac ctgagcgacc tgcttggcaa caagccgagt caccttggta ggcacaacaa
      841 acaatatagc atcaatatca gccaatgctt ccttcaaatc aagggttgcc ttgatggctt
      901 catctaggac aatgtcctta aaataatgac tattagtatg gcgtgtgttg atttcgttga
      961 tttgttcagg gatatttccc catagtcgga cctcatgtcc gttgtcattt aggacctgtg
     1021 ccagggctgt gccccaagag ccaggtccca aaatggctac cttttgtttt ggcattttta
     1081 ttctccttta agagctaatc accttattat atcataagac aaggcctaac tctaatagaa
     1141 aaggtctgct ggcctagcct gtcagctcag tggtgctagc aaagggtaag tagcagggaa
     1201 gatagtcaga tcgtaagcct ttttggttga caatagttcc caagagaact aaaatggtta
     1261 tcatgagaac taaggaggaa ggaaatgcca agaatcattg ctgagcttcg tgaattgacc
     1321 catcaggttg agcaaattag cgaagagatt gctaaaaagt atgacctcca gcatcttgct
     1381 ggtccacaag ggcatgttct tgtctttttg cattgccatc aagacagaga catttttgtc
     1441 aaggacattg aaaaggagct tcaaatctca aaatcggtta cgagtaatct ggtgaagcgt
     1501 atggaaaaaa atggctttat tcgagttgtt gcctcggcta cagataagcg ctgcaagcag
     1561 gttgtcttga cctcggctgg tagggctaag ctgccggtat taaaggagtg ccgcagagat
     1621 attgagcgct attttttcaa ggaaatttca agagaagagc tgctgacggt aaaaaaggtt
     1681 atcgatcagc tgaaacaaaa tatacgagct tataaaggag atacagatgc ttagaaatgc
     1741 tgtgatgaag tataaatggt atgcggctct gtccctagtg atgatttctg gggtcgtagc
     1801 cagtgccctg ctccagccac attacctcaa agatgttcta gctgctatta tggaaaatga
     1861 tcagacaagg attgcagagg tgggtttttg gctgttagtg atagcaggga ttggcttggt
     1921 gtcaggtgcg gtcaatacca tcttgtctgc caagattgct caaggggtat ctgctgatat
     1981 tcgtgagcag acctttagaa agatccaatc cttttcttat gccaatgtgg aagccttcaa
     2041 tgctggaaat cttgtcgtta gaatgacaaa tgatattaat caaatccaaa actttgtgat
     2101 gatgcttttt cagatattgt tgcgcttgcc gattttattt gtcggtgcct ttattttagc
     2161 ggtgcaggcc ttaccgagcc tttggtgggt cttggtgctt gtggttgtga tgacaatggt
     2221 agtcattggg ctggtgatga gccagatggg tcctcgcttt gggatcttcc agcgcttgat
     2281 ggataggatc aatcagattg ctaaggaaaa cctacgcggt gtgcgtgtgg tcaagtcctt
     2341 tgttcaggaa aaaagccagt atgacacatt taaggaggct tcaaatgacc tactgggctt
     2401 gaatttgttt atcggctatg gcttttcaat catgcagcct attttgatgt tggtgtctta
     2461 catggccatt tatttgtcct tgtatctggt ttcagggctg gtcaaaacag atcctgctgt
     2521 tattggaaat atggcttcct ttatgaccta tatgggacaa atcagctttg cgatcacgat
     2581 ggttggtttt atgggaatgc aggcaagtcg tgccttgacc tcgattggtc ggatcaggga
     2641 gattttagaa acagagcctg ctatgacctt tgttaaccat gagcaggagg agctgacagg
     2701 cagtattgtc tttgatgatg tgagctttac ctatccaaat gacagtgaag ccactctaaa
     2761 gcatatttcg tttgaggttg agcccggtca aatggttggt attgtcggtg cgacaggtgc
     2821 tggcaagtcg acccttgcgc agctgattcc gcgtttgttt gacccacagg aagggcaaat
     2881 cctgattggt ggtaaggctc tgccaagcat cagtcaagag actctgcgcg acaccgtctc
     2941 tattgtgctg caaaaggcta ttcttttttc tgggactatt gcggataatc tgcgtcaggg
     3001 caatccctat gctgaccaat tggctttaga aaatgcagca cgcattgcgc aggccaagga
     3061 atttatcgac cgtatggacg ctggctacca gagtgaggta gaagagcgtg gcaataattt
     3121 ttctggcggt caaaagcaga gaatgtcaat tgctcgtggt gtgattaaca atcctaagat
     3181 tttggtgctt gatgattcga catcagctct agatgccaaa tctgaaaagc ttgttcagga
     3241 ggccttgaat aaggagctca aagagacaac aacagtcatc atcgcacaaa aaatatcgtc
     3301 agttgtcaag gcagataaga ttcttgttct tgataatggt cgattgattg gagaagggac
     3361 gcatgctgag ctggttgctt ccaatccgat ttatcgtgaa atttacgaaa ctcaaaaggg
     3421 aagagaggag aactaatgaa gatcctgcga tttttctggt tttattttaa acgttataag
     3481 ctctcttttg ttgtgatatt ctttgctatt gtcctggcaa cctacctgca ggttaaggcc
     3541 cctgtctttt tgggagactc tctagctgag ctgggagaat gggtgcagcg ctattacaag
     3601 gctcaggcgc ttagcaaaat gacgggtcag cccttagttg agccctctat ggcgcctttt
     3661 aggacggtta tgggaaagct attgttggct tatctcttta cagcagtggc taatcttatt
     3721 tatagtctcc tctttacaag ggttatttcg cattcgacca atcgcatgcg taagggctta
     3781 tttggcaaat tggagcgctt gacagttggc ttttttgata gtcacaagga cggtgctatt
     3841 ctatcacgct ttaccagtga tcttgataat attcaaaact ccatgaacca atctctgatt
     3901 caggtcttga caaatattgc tttgtatatt ggtctagtgc tgatgatgtt taggcaggat
     3961 agtcgcttgg ccttggtaac gatagcctca acccctgtgg cgcttattct tctcgttgtc
     4021 atcattacaa tggcccgcaa atatactgat ttgcagcaaa aggaggtcag tgctttaaat
     4081 gcttacatgg acgagaagat ttctggccag aaggctatta ttgttcaagg ggtgcaacag
     4141 gatgctattg atggctttat tgagcacaat gagagggtgc gtgcagcaac ctttaaggga
     4201 cgcctttttg ctggtctgct gtttcctgtg atgaatggga tgagtctttt gaatacagct
     4261 attgtcatct ttgctggctc aaccattgtc cttggtgaca agtccatgtc aacagctgct
     4321 gctcttggct tggtggtgac ctttgttcag tattcacagc agtattatca accgattatg
     4381 cagattgcct ctagctgggg tgaattgcag ctggccttta caggtgctgg tcgtatccaa
     4441 gaaatgttcg atgaaaaaga agaggttcgc cctgagcatg ctcctgtctt tacagcatta
     4501 aaagaagggg ttgagattaa gcatgttgac tttggttatc tgccgggaca aaaaattctg
     4561 tcagatgtgt cgatttcagc ttcaaagggg aaaatggttg ctgttgttgg accgacaggg
     4621 tctggcaaga ccacgatcat gaatctgatt aatcgttttt atgatgttga tgctggctct
     4681 attacctttg atggtcgtga tattagggaa tatgacttgg atagtctgcg tcagcgggtt
     4741 ggtattgtcc tacaggagtc agtcttgttt tctgggacta ttgctgataa tatccgcttt
     4801 ggtaatcaga caatcagcca aaaagaggtt gagacagcag cgcgtgcaac gcatattcat
     4861 gagtttatca tgtccttgcc tgatggctac caaactcagg tgtcagatga tgagaatgtc
     4921 ttttcaactg gtcaaaagca gcttatttca attgctcgta cgctgttaac cgatcctcag
     4981 gtcttgattt tggacgaggc aacatcaaat gttgatactg ttactgaaag taagattcaa
     5041 aaggctatgg aggctatcgt ggcaggtcgc acaagcttcg tgattgccca ccgcctaaaa
     5101 accattttaa atgctgatga aatcatcgtt ctaaaggacg gtaaggttat tgagcaggga
     5161 agtcaccatg agctgctaag gcaaaagggc ttttatgccg agctttatca caatcagttt
     5221 gtgtttgagt agcttctaaa aatgatcatt acataagctg ctgttgttat tcttaaaaac
     5281 catcaaaaca gcttttgccg atcgactccg ctttggcgga gttttttgat gcaaagcatg
     5341 tcaaggcaat gtgctataat aaaagagaca gacaatagaa ggtagaagat gtaatgattg
     5401 acttacaaga gattctagct agaatgaatc caaaccagaa aataaactat gatcgggtca
     5461 tgcagcagat gaccaaggtc tgggcgaggg agtctatacg tcctcgcatt ttgatgcatg
     5521 tttgctgtgc tccctgctca acctacacgc tggaatattt aacccagtac gctgatatta
     5581 cggtttattt tgctaattca aatattcacc caaaggacga ataccaccgc agggcctatg
     5641 ttactcagaa atttgtagca gagttcaacg ataaaacagg taatagcgtg cagtttatcg
     5701 aggcagatta tgtgccaaat gaatttgtca agactgtccg aggcttggag aaagagtctg
     5761 agggcgggga tcgttgtcgt gtttgctttg attatcgctt ggacaagacg gcacaaaagg
     5821 ctgtggagct gggctttgat tattttgcta gtgccttgac catcagccct cataaaaact
     5881 cacagacgat taacgatgta ggcattgatg tgcaaaaggt ttacaccact aagtatttgc
     5941 ctagtgattt caagaaaaat aatggctatc gcaggtcggt cgaaatgtgt gaggaatatg
     6001 atatttaccg ccagtgctat tgcggctgcg tctatgctgc aaacatacaa gggattgatc
     6061 tggttcaggt gaaaaaggac gccaaggctt ttatggcaga taaggatttg gaggctgatt
     6121 ttccaaggat tcggtttagc tatgccggca aggagattta gccctcttgc attttgttgc
     6181 gttatagagg ggggcagtcg gtgatttttg gggtgcagcc cctacttttt tgctattcct
     6241 ttacgaatat tttataataa gaggactaaa aaaagaaaag ggataagagt gcttttgtct
     6301 gctgtcctgg caggtgattt tacagctgct gcaggcactg acaagggctc ttgaggttaa
     6361 tcatgacaag gattcgaggc tttgagcttg tgtcaggctt tactgatact gatttattac
     6421 caaaacgtga gacagctcat gcagcaggct atgacttatc tgttgcagag gagaccagca
     6481 ttgcaccagg tgagattgta cttgtgccaa caggggtcaa ggcgtatatg caagacggtg
     6541 aggtgcttta tctctatgat cgctccagca atcctcgtaa aaagggactg gttctgatca
     6601 attctgtggg tgttattgat ggtgactact atggtaaccc tgcgaatgaa gggcatattt
     6661 ttgctcagat gaaaaatatt acggatcaaa ccattacctt gtcagctggt gagcgcattg
     6721 ttcagggcgt atttatgcct tttttgattg ctgatggtga tcaggctggt ggtgagcgga
     6781 caggtggttt tggttcgaca ggaggataag gtattagcag gctgcttcac gtgcttgtag
     6841 ccagttgatg cttagattca aggaggaaat gtgttatagc taagaaaaag gcgaggttta
     6901 tctgtggaga atgtggctat cagtcaccca aatatctggg gcgctgccct aattgctctg
     6961 cctggtcttc ctttgtagag gagacagagg tcaaggacgt caaaaatgcc cgtattagcc
     7021 tgactggaga aaaaagtaag cccatcaagc taaagcatat caatggcgtt cgctaccagc
     7081 gtatccagac agagatgaat gagttcaatc gtgtgctggg cggtggtgtt gtgccgggga
     7141 gcttggtttt gattggtggt gatcctggta ttggtaagtc aacgctgctc ttgcaggttt
     7201 ctatccagct tgcggataag ggaactgttt tatatgtctc tggagaggaa tcggcagagc
     7261 agatcaagat gcgcagtgat cgtttgggac agaccgacaa tgatttttac ctctatgcgg
     7321 agaccaatat gcaggctatt cgagcagaga ttgaagccat tcagccggat tttttgatta
     7381 ttgattctat tcagacgatc atgagtccgg agatttcggg tgttcagggc tcggtcagtc
     7441 aggttcgaga ggtcactgct gagctgctcc agctagctaa gtctaatcat attgcaacct
     7501 ttattgtagg acatgtcacc aaggagggca ccctagcagg gcctcgcatg ctggagcata
     7561 tggttgatac ggtcctttat tttgagggtg agaggcatca tacctttcgt atcttgcgag
     7621 cggttaaaaa tcgttttggc tcaaccaatg agattggtat ttttgacatg caatcaggtg
     7681 ggctagtgga ggtcctcaat cccagtcagg tgttcttaga ggaacgatta gacggcgcaa
     7741 caggctctgc tgtggttgtc accatggagg ggagcagacc gattttagct gaggtgcagg
     7801 ccttggtgac accgactgtt tttggtaatg ctagacgaac gacaactggg ttggacttta
     7861 atcgcgtcag tctgattatg gctgtcttgg aaaagcgatg tgggctgctg ctacaaaatc
     7921 aagatgccta cctcaagtca gcaggcggtg tgaagctaga tgagcctgct attgacttgg
     7981 cagttgctgt ggccattgcc tctagctaca aggaaaaacc aaccaaccct caggaggcct
     8041 ttttaggaga gattggcttg actggtgata ttcggcgtgt gacccgtatt gagcagcgga
     8101 ttaatgaagc cgctaagctt ggctttacca agctttacgc tccgaaaagc tcattgcagg
     8161 ggattgatct gccaaaaggg attgaggttg ttggtgtgac gacagtagga gaggtcttaa
     8221 aggctgtctt tacttaggtt gttgttttta acatgaggac taggggagct attcctagtc
     8281 ttttttattt taagaccagt agtattggaa ggtccttata gtgttccgta gaaccaaaaa
     8341 gcccttagag agctagcctc taagagcctt atgatatgga tagcgtatta gtagatctta
     8401 gaagctttta aaccactgcc atataaagtt aaaccagcct gaaatccaag tgaaaaatgg
     8461 cgatcgtgaa ggcgcttggt aatcttgatt aaaaagaatg tcccatcctc caatatcctt
     8521 aggacattta aaccatccat tacctagatc gatacagctg tctccactaa cctgactggc
     8581 atatacggtc tgtggttgtg tctggcctgt gctgatagga cctagggtta ggacagcagc
     8641 agcagccaat aagcagatta tttttgtttg tttcattgct attctcctta atttagtatt
     8701 attggcttag cagctagcga ctgccaaggc cttctgagaa gagtttagca tactggctga
     8761 tagcgagaaa tagcaattta tcagtttgtc tccgtagttt cgttttttaa ttaaaatgac
     8821 aattaactga ttttgtcacg ttcttgctgc ccttacttta gcggctcaaa gggcgggctg
     8881 ctaagcttgc ttccaatgtc aaggctggct cacctacctc tggtttcagt taggctagtg
     8941 ctatctgctt gtgttaaaaa gcagttcagc attcagacat ttcaggcaaa agatgataag
     9001 atagacagac agctcaaggc tgagatagct tagagattag tctgggagga ccgtattcat
     9061 gtcatatttt gaacgctttt tatctgccaa tgaagcctat gtcgccttac atgggactgc
     9121 tcatttgccc ctaaagccca aaactaaggt agctattgtg acctgtatgg actcaagact
     9181 gcatgtggcg caggccttgg gtttagcgct tggtgatgcc catattttac gcaatgctgg
     9241 tggacggata acagatgaca tgcttcggtc tcttgtgatt tcgcagcagc agctgggaac
     9301 gcgtgagatc gttgttcttc atcatacgga ttgtggggcg caaaccttta ccaatgaagc
     9361 ctttacagcg cagcttcatg atactctggg agtagatgtg tctgactgtg attttctccc
     9421 ctttactgat gtggaagcaa gtgttcgtga ggatatggct atattgcagc aatcaccgtt
     9481 gattccaaaa gacgtggtca ttagtggtgc ggtctatgat gttgccactg gacgtatgtc
     9541 tcaggtggcg atgccgaaat cctgacagct gatcggtttg tagtatggct ttgagactgg
     9601 ttaggaatgg cggcgacagt agctagtgga caatgctgcc aaaaaagact atacttgatt
     9661 gtatcaacaa aatcatacaa aggagtggtg ttatggccta taatcgaatg acctatacta
     9721 ttgacagcag catgcagttt cctcttgttg aaattgattt ggacatgggg gagtctgtct
     9781 ttctacaaaa aggcagtatg gtttaccaca caccgtcaat cagcttaaac accaagctca
     9841 atgggcgtgg ctcaggtctt ggcaagctgg ttggtgccat tggccgttca atggtttcag
     9901 gagaatccat gtttatcaca caggcgattg ctaatgatgt tagtggcaag ctagcgcttg
     9961 ccccttcaat gcctggtcag gttattgctc ttgagctagg ggtagatcaa taccgtttga
    10021 atgacggagc cttcttggct ttagatggct cagctcacta caccatgaag cgccaaaaac
    10081 ttggtaaggc cttatttagc ggtcagggtg gcttctttgt gatgtcaaca caaggagaag
    10141 gaaccctatt ggtcaatgct tttggttcga ttaaaaaaat cacgcttcat ggcgacagca
    10201 tgacgattga taatagccat gtggtggctt ggagtcagga tttggattat gatattcatt
    10261 tggaaaatgg ctttatgcag tctattggta caggtgaggg agtggtcaat acctttagcg
    10321 gatacggaga tgtctatgtg caaagcctga accttcagca atttgctgga gttttacaga
    10381 gctatattgt cacaggcggc cattaagcag ttggaagtaa accaagcctt gccaattgat
    10441 ggattgaaat ggatatgaca ggttcgtggt tgccagagta tattgtcgct ttctttgctg
    10501 gggtgtagct tgacatcaat gcaggtcaat agcctgacta atatctatag ctaggcatgc
    10561 tatgaagcta ttgaaagagg cagcactgct tgccaatgag ctgcttatag agctatccta
    10621 gctctaggcc acgccaaacg cataaggatc tttacgtttt tgatagcgat tttctcatca
    10681 gtggtatggt ctttttcaaa tcaattcagg ctacaattaa gctgaatgtg aacagctgat
    10741 gatatcaaaa tatcagaagt agatgaaaac aatgcatgta gctagaaaat ggttacatgc
    10801 attttcgtta tgcagctgtt ctaagttgat ttttgtcgcc caatgcttga agttgtgcta
    10861 taataggagc gattgaaatc tttagatttc caagggatta gctgtatttt tgttccttat
    10921 cgaccatttt ctcatagagc aagcctaccg taggaacggt ttatagccca ggatcccttc
    10981 tttcaatgaa accataggag aaaaagaatg tctaaaccaa ttcgtgtgcg ctatgcacca
    11041 agcccaacag gccttttaca tatcggaaat gcgcggacag cgctctttaa ctatctttat
    11101 gctcgtcatc atggcggtga ctttattatt cgtattgaag atactgatcg taagcgtcat
    11161 gtcgaggacg gcgagcgttc tcagctggaa aatttaaaat ggcttggtat agattgggac
    11221 gaaagtcctg agacgcacga gcgttatcgt cagtcagagc gtctagccct ttatcaacaa
    11281 tacattgacc aattattggc agaaggcaag gcttacaagt cttatgtgac tgaggaggag
    11341 ctggcagcag agcgtgagcg tcaagaggca gctggtgaaa cacctcgcta tgtcaatgaa
    11401 taccttggca tgtcagcata tgaaaaggcg gcctatattg cagagcgtga agcagcaggt
    11461 attgtgccta cggttcgttt agcggtcaat gaggctggtg tttacaaatg gacagacatg
    11521 gtaaaaggcg atatcgtatt tgagggtggc aatgtcggtg gtgactgggt aatccagaaa
    11581 aaagacggct atccaaccta caattttgct gttgttattg atgatcacga tatgcaaatc
    11641 tcacacgtta tccgcggaga tgaccatatt gccaatacgc caaagcagtt gatggtttac
    11701 gaggcgcttg gctgggaagc acccgtcttt ggtcatatga cccttatcat taattctgag
    11761 acaggtaaaa agctatcaaa gcgtgatacc aataccctgc agtttattga ggattaccgc
    11821 aaaaaaggct atatgccaga ggcagtcttt aattttattg cccttttagg ctggaatcct
    11881 ggcggggagg ctgagatctt ttctcgtgag caattgattg ccttatttga tgagattcgt
    11941 cttagcaagt cgccagcagc ctttgatcag aaaaaaatgg actggatgag caatgagtac
    12001 tttaagcatg ctgatcttgg cgctgtatat gcgctttgta agccatttct tgaagcagca
    12061 ggccgcttga ctgaaaaagc agagaagcta gttgagctct atcagcctca attaagctct
    12121 gctgatgaga ttgttccatt gactgattta tttttctcag atttcccaga gctgaccgca
    12181 aaagaaaaag aagtgatggc agctgagact gttccaacag ttctgaaggc cttcaaggaa
    12241 aagctagagg cgatgtcaga tgaggacttt aagccagaaa acattttccc acaaatcaag
    12301 gctgtccaaa aagaaaccgg cattaagggc aagaacctct ttatgccaat tcgtattgct
    12361 gtttctggag aaatgcatgg cccagagctg ccaaatacca tttacctcct tggacgtgaa
    12421 caatcgattg agcatattgc caatatgctt taaacactat cgcagctagt agtttggtct
    12481 aggctggacg atgatcataa ataacatcat gaatgaagca gagatgagat atctgatgtt
    12541 tgcttcattc ttttttagtg tgcttgagct agcgacacga cgcccagtag cgcatagcta
    12601 gatgtcataa tccagcaggc ttatctgctt aatttttgat gagcgtggaa gatattatta
    12661 aaataaatat taaattgtca ctggttttct tagattattt gttatacaat atttttccct
    12721 agataaggta aggctggtca gatattttaa tttgctttaa tgattgacat ctgatttgca
    12781 aacgctgtca caaaccagct atggactgtt tttgcgcttg ctgaattata taaaaaattc
    12841 ata
//
LOCUS       DARYYD010000053        12532 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.054, whole genome shotgun sequence.
ACCESSION   DARYYD010000053 DARYYD010000000
VERSION     DARYYD010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12532
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.054"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            1059..1129
                     /locus_tag="TV188_001562"
     tRNA            1059..1129
                     /locus_tag="TV188_001562"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1091..1093,aa:Thr,seq:ggt)
     gene            1657..1911
                     /locus_tag="TV188_001563"
     CDS             1657..1911
                     /locus_tag="TV188_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008087830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEL1534899.1"
                     /translation="MSYEQDFLRDFEDWVKAQIQVNQLAMATSRQIAKEDNDQRARDA
                     FIRYESKLDAYEFLLGKFDNYNKGKAFHEVPDSLFGSRHY"
     gene            1933..2433
                     /locus_tag="TV188_001564"
     CDS             1933..2433
                     /locus_tag="TV188_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1534900.1"
                     /translation="MARRYNRKKQYKLQLKRQGLLKAVINQVEQTVEKVVDKTKEAVH
                     TASQMVTASKTETADLQDKQSIAEKAAQPKADVASSSLADSSEVSSEKEASKASSEVL
                     SRDAFAELAEVSELRADIVTVLFEAGIRSAAAFSQWTEAELLALKGIGPATISKLKEN
                     GVNFKK"
     gene            2693..3277
                     /locus_tag="TV188_001565"
     CDS             2693..3277
                     /locus_tag="TV188_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEL1534901.1"
                     /translation="MIEIMGSVENNRLPDVKTSRLLLRQRTLADVEAIFAYASRPEVS
                     YPAGFPPVKTLEEEEHYIANTMPKRWLLQQLPAGYGIALKGDNRIIGSVDFNNRHADD
                     VFEMGYLLHPDYWHQGIMTEAASALLEVAFTLLKLHKVEISCYDYNMGSRRIAEKLDF
                     TLEATIRDRKDAKGNRCADLRYGLLKREWERQCR"
     gene            3477..4040
                     /locus_tag="TV188_001566"
     CDS             3477..4040
                     /locus_tag="TV188_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEL1534902.1"
                     /translation="MNIILIGAQASGKMTIGQELEKLTDLTLFHNHESIDFVTKFIPM
                     SSEARELIDELRLLFFKTFAKRQQSIIFTVVIDFNAPEDIAFLETLQSVFHDFDREVL
                     FVELEIDLKERLRRNKTENRLYHKPIKRHLEWSEKDILDTAKFANFNPAKVPENLKYY
                     CKINNTSLSAQETAQFIVQKMKELEVS"
     gene            4053..6704
                     /locus_tag="TV188_001567"
     CDS             4053..6704
                     /locus_tag="TV188_001567"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEL1534903.1"
                     /translation="MSKELSPKYNPAEVEAGRYQAWLDQDVFKPSGDKKAKPYAIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLREQG
                     ISRYDLGRDKFLDKVWEWKDEYAATIKEQWGKLGLSLDYARDRFTLDEGLSKAVRKVF
                     VELYKKGWIYRGEFIINWDSAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALQVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGQHVVLPIVNKLIPIVGDEHADPAFGTGVVKIT
                     PAHDPNDFEVGGRHNLPQVNVMNDDGTMNELAGEFAGMDRFEARKAVVAKLEEIGALV
                     EIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTDDKVDFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNEAGDMYVGEEAPAGDGWKQDEDVLDTWFSS
                     ALWPFSTMGWPDVDSEDFQRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRKPFSNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIEKYGADSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLEQASANVEQVASGAAGNVTDCWILHNLNETIGKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDEKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTADYPTVDPAFENEAAHKGVESLKDLIRTVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPERLKIASSIVTPELAMSA
                     VITGAEIFLPLADLLNVTEELARLEKELAKWQKELDLVSKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVERIKEMEKLVR"
     gene            6917..7405
                     /locus_tag="TV188_001568"
     CDS             6917..7405
                     /locus_tag="TV188_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013642832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HEL1534904.1"
                     /translation="MTTAATKASVPHKEKMESKEPETSHQPEAYPDLASYQELAVHVS
                     IADQVMTIIGDGKVIFKTSVSTGAKESPTPTGTFVIEPERGDFFFNQASEEGAYYWVS
                     FKDHGIYLFHSLPTDQYGNEIPEEAERLGQPASHGCVRMSRADAKWFYDNIPEGISVT
                     IE"
     gene            complement(7608..8408)
                     /locus_tag="TV188_001569"
     CDS             complement(7608..8408)
                     /locus_tag="TV188_001569"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534905.1"
                     /translation="MKKKLVMSLIVNLPLLSLICFNEVSANSDYENSPVLGQGYYGYD
                     DYTEAPQIGDQKVIGFRRDWENARDFGVKPIKNNDKEIVVKTSPGSLIRIFKVEEDDK
                     ETELVQVQKKSNGDLTNNRYYPIAKWDGKIVFSLESARTQKTNSKEETYVPYNKIASN
                     GDKFRVHITSDGFVLGSEIWIVGESKPQDIIEQEQKKAQKELEEQKKQENLRQQIKKE
                     REHSQKRVVENIYLKEIRENAHKSWHKRLNEKIQEQWSKFTVFLNKYY"
     gene            8919..9155
                     /locus_tag="TV188_001570"
     CDS             8919..9155
                     /locus_tag="TV188_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEL1534906.1"
                     /translation="MTFEEILPGLKAKKKYVRKGWGGAENYVQLFDSIEQNGVALEVT
                     PYFLINVSGAGEGFSMWAPTPCDVLATDWVEVYD"
     gene            9148..9846
                     /locus_tag="TV188_001571"
     CDS             9148..9846
                     /locus_tag="TV188_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEL1534907.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLRNGFTVYGVDKAKKPDLSGDF
                     QFLQLDITGDLAELFEAVPRVDVLCHTAGVLDAYKPLLDTTQADFEALFQVNFFAAVR
                     ITRHYLAQMLTAQSGIIINMCSIASFMAGGGGAAYTSSKHALAGFTRQLALDYAKAGI
                     QVFGIAPGAVQTAMTATDFEPGGLAQWVADETPIGRWLRAEEIAELTMFLASGKASAM
                     QGEIVKIDGGWSLK"
     gene            10046..10504
                     /locus_tag="TV188_001572"
                     /pseudo
     CDS             10046..10504
                     /locus_tag="TV188_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623303.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
     gene            10505..11479
                     /locus_tag="TV188_001573"
     CDS             10505..11479
                     /locus_tag="TV188_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEL1534908.1"
                     /translation="MKLALVGTGMIVKEVLPVLKEIKSIDLMAIVSTPRSLETAEALA
                     DAFGIQQASCQLAEVLKNEEVDTVYVATPNHLHFEVAKQALEAGKHVICEKPFTMTAK
                     ELDALSSIARAKQLILLEAITNQYLPNTQFIKDHLTELGEIKLVECNYSQYSSRYDAF
                     KRGEIAPAFDPKKGGGALRDLNIYNIHLLVGLFGKPQTVQYLANMERQVDTSGVLLMD
                     YERFKAVCIGAKDCSAEIVSTIQGNKGFLSVLGAPNAVPELLLAIRGEQARTVNFNHP
                     SHRMYDEFIAFSDIISNKDMERAEQALEHSKAVMAVLEQAAASLESDS"
     gene            11835..>12532
                     /locus_tag="TV188_001574"
     CDS             11835..>12532
                     /locus_tag="TV188_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEL1534909.1"
                     /translation="MPNYAIILAAGKGTRMKSGLPKVLHKVSGLSMLEHVLNSVSALA
                     PQKQLTVIGHQAEQVRAVLGDQSLTVVQEEQLGTGHAVMMAEEELSGLEGQTLVIAGD
                     TPLIRGESLKALLDYHIREKNVATILTANAKDPFGYGRIIRNVAGEVVNIVEQKDANE
                     AEQEVKEINTGTYIFDNKRLFEALKHLTTDNAQGEYYLTDVISIFKAGQERVGAYLLK
                     DFDESLGVNDRLALA"
BASE COUNT         3616 a         2398 c         2942 g         3576 t
ORIGIN      
        1 cgattttata tctattggct cccagattag ctttttcagt aacaggtgta ttatttcctg
       61 atgtttttga taatttattc ttggtttata atattttaat gacacttgct ttttggcttg
      121 cgatttattc tgttgacctc ccagaaaaat agttgcggga cttgtttagt agttggttaa
      181 caaagggtag atgatcagtt aaaggtgaag cgtctgagct atgttggcca ttatgcgtac
      241 agctggcaaa atgcttttga tccaatcggt taaacctcaa gctattctct ttgggataac
      301 aaatacccca tctgtctcag acaaagaatg gcaacgccta aataggatta acatctgcaa
      361 gtgctcttgg gactgccaat gctcttagta gcataggtga tttttcagcg ctagagactt
      421 ttcagcagat gagaaatagt cgcaataaac gaagacaaaa agacttggct tgagctcgta
      481 tttggcctta aaatagtagt cagtcgagct taaaaaaaag tcattgcagc ttatgaaggt
      541 tatcgtatcc ttatttcaac tgagctaggt aagctaggga gtttccttta ggtgtaacga
      601 tagaagcgat caaataatta cttcatttaa agataaggat tgtaataagc atagaaaaga
      661 gcagttactt gacataacta ctcaatgtaa aaccgtttca ggcggtggct tttgttatta
      721 gataaaaaat aatcgtcatc attcggccaa agttagaacg gttatgtttt atgctcatct
      781 ttgaagatgt tatagcacaa gccaataggg agactaaagc ttaaaaagag tttgagtagc
      841 ttcaaaggct gctagctttt tggcctcctc cattttgtta gctgttgatg aatcgcccat
      901 aggcaccacc acccactcag aacgagcagc cacctgtctt aattttttta ctctaccact
      961 gtagcatgcc acaagaaaaa atcagaacac taatgacatt ttaaaaaaaa aaaaaaagac
     1021 ttgcacacca aaacaagtta tagtatcata gaaaggtagc cgctatagtt aaatggtata
     1081 ataaagcaat ggtaatgctt cgttccgagt tcgattctcg gtggtggcat ctgagtactg
     1141 tcctaagtct tattaggacg gtttttttat tgctaggtga accaatagta gtcatctgtg
     1201 aatcattacc atagtggctt ctgttcgccc aagcatagca aagctgctgt cagaatgaac
     1261 ccagccaaca atgtcaatag aagcagcacc agacaagcct ttagtcaccc atgctttaaa
     1321 gattttacgg ctgtaatgtt agtaactgtt acctgttttg ttcaagttgt ctgtgacatc
     1381 aaatcacttg atgctaccag tactgtcaat acattagctg tcacttggca gttgttctga
     1441 ctactactaa aaatagcagc tatcagcgtt gcaatcaaaa aagaatgcga atcaagctct
     1501 cctgatcagc ttaacttttt gaaagagttt gtacgggtca agcatcagca agtcagactg
     1561 ccttatttgt ttttatcata agcttctaag aaaatagcac aataagccag gctgtggtat
     1621 aatggtaagg attaagtcag aaagaggggg gcagacatgt cttatgagca agactttttg
     1681 agagattttg aagactgggt gaaggctcaa attcaggtca accagctagc tatggcaacg
     1741 agccggcaaa ttgcaaagga agataatgat caaagagcca gagatgcctt tattcgttat
     1801 gagagtaagc tagatgctta tgagttttta ttaggaaaat ttgataatta taataaaggt
     1861 aaagcttttc atgaggtgcc agacagccta tttggtagcc gtcattatta gaggaaggga
     1921 taagcagtaa tcatggcaag acgatacaat cgtaaaaaac aatacaagct acagcttaag
     1981 cgtcaaggac tgctcaaggc agtaatcaat caagtggagc agactgtgga aaaggtggtt
     2041 gataagacta aagaagcagt gcataccgct tcacaaatgg taacagcatc aaagacagag
     2101 actgctgatc tacaggataa gcagagcatt gctgaaaaag cagctcagcc taaagcagat
     2161 gtagcttcta gtagcttggc tgacagttct gaggtttcaa gtgaaaaaga ggcctcaaag
     2221 gctagcagtg aagtcttatc acgcgatgct tttgcagagt tggctgaggt ttcagagctt
     2281 cgggcagata ttgttacggt gctttttgag gctggtatta ggtcagctgc tgcttttagc
     2341 caatggacag aggcagagct tttggcgctt aagggaattg gaccagcgac tatcagcaag
     2401 ctaaaggaaa atggtgtcaa ctttaaaaag tagtctgatt tttattgctt aataagtata
     2461 aatttgttag aatgttagca atcagaggta tcttgagttt gtctgttaca gagagcggtg
     2521 gtgttgagaa atccgcacag atgtcaagtt atgtagctga ggcttacaat ggaaaaatga
     2581 taaagcagca gattaagtgt aatctgaaac agtggtggta ccgcggatta ttagtgaatt
     2641 cgtccctgtc tagtcgattg actaggcggg gttatttttt ggaggacttg ctatgattga
     2701 gataatgggt tctgttgaga ataatagatt accagatgtc aaaactagtc gtttgctgct
     2761 gcggcagcgt actttagctg atgttgaagc gatttttgct tatgctagcc gacctgaggt
     2821 tagttaccca gcaggctttc cacctgtgaa aacccttgaa gaagaggagc attacatcgc
     2881 aaacacgatg cctaagcgct ggcttttgca acagctgccg gcaggctatg gcattgccct
     2941 aaagggtgac aataggatta ttgggtctgt tgattttaac aaccgtcacg cagatgatgt
     3001 ctttgaaatg ggctatctgc tccaccctga ttattggcat caggggatta tgactgaggc
     3061 agcgagtgcc ctgctagagg ttgcctttac tctgcttaag cttcataagg ttgaaatcag
     3121 ctgttacgat tacaatatgg ggagtcgtcg gatcgcagaa aagctagact tcactcttga
     3181 ggcgaccatt cgtgatcgca aggacgctaa aggcaatcgc tgcgcagact tgcgctatgg
     3241 actgttgaaa agagaatggg agaggcagtg tagataagga gtagactctc taaaatatgc
     3301 gttaatctgt caaaagcatt tcataagaag tcctcaaact caaagcgctt atgactacca
     3361 aaactggtta gcgcttcgcc aaccagtgtc atcagtttct ggtagtctgc cttgagcagc
     3421 aagtgttatg ttaagtgagg tgagaagagg taagagagat cggaaagagg tttggtatga
     3481 atattatctt aattggagca caggcgtctg gtaagatgac aattggacag gaattagaaa
     3541 aactgactga cctgacttta tttcataatc atgaatcgat tgattttgtg actaagttta
     3601 taccaatgtc atcggaagct agagaactaa ttgatgagct acgattgcta ttttttaaaa
     3661 catttgcaaa acgtcagcaa tcaattattt ttactgttgt cattgatttt aatgcacctg
     3721 aagatatagc gtttttggaa acactacaga gtgtgtttca tgatttcgac agagaggttt
     3781 tattcgttga attagaaata gatttaaaag aacgcttaag gcgaaataaa actgaaaatc
     3841 gactttacca caaaccgata aagcgtcatt tggagtggtc tgagaaagat attttggata
     3901 ctgctaaatt tgctaacttt aaccctgcaa aggtaccaga aaatcttaaa tattattgta
     3961 aaatcaataa tacgagtctt tctgctcaag aaacagcgca gtttatcgtc caaaaaatga
     4021 aagagttaga agtaagctag aaaggacacc atatgtcaaa agaactttca cccaaataca
     4081 atccagctga ggttgaggct gggcgttatc aagcttggct ggaccaagat gttttcaagc
     4141 catcaggcga caagaaggct aagccgtatg ctatcgtgat tccaccgcca aacgttacag
     4201 ggaagctgca ccttggtcat gcttgggaca cgacccttca agatattatt attcgtcaaa
     4261 agcgcatgca gggctttgat actctctggt tgcctggtat ggatcatgca ggtatcgcca
     4321 ctcaggctaa ggtcgaggag cgcttgcgcg agcaggggat ttcccgttac gatctcggtc
     4381 gtgacaagtt cttagacaag gtttgggaat ggaaggacga gtatgcagca accatcaagg
     4441 agcagtgggg taagcttggg ctttcactag actatgcgcg agatcgcttc actcttgatg
     4501 aggggctctc aaaggctgtt cgcaaggttt ttgttgagct ttacaagaaa ggctggattt
     4561 accgcggtga gttcatcatc aactgggact cggcagctag gacagctctt tcagatatcg
     4621 aggttatcca taaggacgtt gagggtgcct tctaccacat gaactatatg ctagaagatg
     4681 gttcgcgcgc ccttcaagta gcaaccacac gtcctgaaac catgtttgga gatgtggctg
     4741 tcgctgtcaa tccagaagat cctcgttaca aggacttgat tggtcaacat gttgttctgc
     4801 caatcgtgaa taagctgatc ccaatcgttg gagacgagca tgcggatccg gcattcggaa
     4861 caggggttgt taaaatcaca ccagcccatg acccgaacga ctttgaggtt ggtgggcgtc
     4921 ataatctccc acaggttaat gtcatgaatg atgatggtac catgaatgag cttgcaggtg
     4981 aatttgcagg tatggatcga tttgaagctc gtaaggctgt tgtggctaag ctagaagaaa
     5041 tcggtgccct tgttgagatt gaaaagcgtg ttcattcagt aggtcattca gagcgtacag
     5101 gtgttgtggt tgagcctcgc ttgtcaacac agtggttcgt gaagatggac caattggcta
     5161 aaaatgctat tgccaaccaa gacacagatg acaaggttga cttctaccca ccacgcttca
     5221 acgatacctt cttgcaatgg atggaaaatg tccacgactg ggtaatctct cgtcagcttt
     5281 ggtggggaca tcagatccct gcatggtaca acgaagcagg tgacatgtat gttggtgagg
     5341 aagcgccagc aggtgatggc tggaagcagg acgaggatgt ccttgacacc tggttcagct
     5401 ctgcgctttg gccattttca actatgggct ggcctgatgt agactcagaa gatttccaac
     5461 gttacttccc aacgtcaaca ttggtaacag gttacgacat catcttcttc tgggtgtctc
     5521 gtatgatttt ccaatcgctt gaatttactg ggcgtaagcc tttctctaac gttcttattc
     5581 atggtctgat tcgtgacgaa gagggacgca agatgtctaa gtcgcttgga aatggcattg
     5641 atccaatgga cgttatcgaa aaatatggtg cagatagcct acgctggttc ctatcaaatg
     5701 gctcagcccc tggtcaggac gtgcgcttct cctatgaaaa aatggatgcg tcctggaatt
     5761 tcattaacaa gatttggaac atttcacgtt acattctcat gaataatgag ggcttgacac
     5821 ttgagcaagc aagtgcaaat gttgagcaag ttgcgtctgg cgctgctgga aacgtgacag
     5881 actgttggat cctccacaat ctcaatgaaa caatcggtaa ggtcacagag aactttgata
     5941 agtttgagtt cggtgtggca ggtcatatcc tctacaattt tatctgggaa gaatttgcca
     6001 actggtatgt ggagctgacc aaggaggttc tgtacagcga caacgaagac gagaaggtta
     6061 tcactcgctc tgttctcctc tacacgctgg ataaaatcct gcgtctcctt cacccaatca
     6121 tgccgtttgt gacggaagaa atctttggtc aatacgctga aggttctatc gtgacagcgg
     6181 actatccaac ggttgatcct gcttttgaaa atgaagctgc gcacaaaggc gtggaaagtt
     6241 tgaaggactt gattcgtacg gtgcgaaatg cgcgtgcgga ggttaatgta gcaccaagta
     6301 aaccaatcac tatccttgtc aaaacaagcg atagcgacct ggaagccttc ttcaacagca
     6361 atgtcaacta catcaaacgc ttcacaaatc cagagaggct taagattgct tcaagcattg
     6421 tgactcctga gttggccatg tcggctgtta ttacaggtgc agaaatcttc cttcccctag
     6481 ctgatctgct caatgtcaca gaagaattag ctcgccttga aaaagaatta gctaagtggc
     6541 aaaaagagct tgacctggtc agtaaaaagc tcagcaatga acgcttcgtt gctaatgcca
     6601 agccagaagt cgttcaaaaa gaacgcgaca aacaggctga ttaccaagct aaatacgatg
     6661 caaccgtaga gcgcatcaag gaaatggaga agttagtaag gtaggatagt gatcatctaa
     6721 gagccaattg gctctttttt tgatatactg tcaaggagta atcatcacaa ttatctatat
     6781 aagtcaaagg agtgtctcat gaaaaaaaga gtcattggtt ggttaggtgt gctggtaata
     6841 gggcttatgc ttggtctgat atggtggaaa tggttagtgg cagatcggcc actaacccaa
     6901 gcaggtcaag gaagtcatga ccacagcagc gacaaaggcc tcagtgccgc ataaggaaaa
     6961 aatggaatca aaagagcctg agacatcaca tcagccagaa gcctatcctg atcttgctag
     7021 ctatcaggaa ttggctgttc atgtgtcgat tgcagaccaa gtcatgacca ttataggaga
     7081 tggtaaggtt atttttaaga ccagcgtgtc aacaggagca aaggaaagtc caacaccgac
     7141 agggaccttt gtcattgagc ctgagcgagg agactttttc ttcaatcagg catcagaaga
     7201 gggagcttat tattgggtgt cctttaagga ccatgggatt tatctgtttc acagcctacc
     7261 aacagaccaa tatggcaatg agattccaga ggaggcagag agactgggac agccagcctc
     7321 acatggctgt gtccgcatga gcagagcaga cgccaaatgg ttttatgaca atatcccaga
     7381 aggcatcagc gtcacaatag aatagcccta atctccctca gaatagcctg agcagataga
     7441 ggaagagcct gttaatatta gcaggctttt aaagctcctt aaaaggctgc aaaaaggaac
     7501 gaaaaaagac ctgaaacagg tccattgatc taagagaaga caagtaacta gccttctagc
     7561 aaagtgtttt aaaaatgcgt tagtttagta gcttcgtgat aatacaatta ataatattta
     7621 tttaaaaaaa ctgtaaattt cgaccactgt tcctggattt tttcatttaa acgtttatgc
     7681 catgacttat gagcattctc tctaatttct tttaggtata tattttctac tacccttttt
     7741 tgactatgtt ctcgctcttt ttttatttgc tgtcttaaat tctcttgttt tttctgttct
     7801 tctaactctt tttgagcttt cttctgttct tgctctatta tgtcttgagg tttagattct
     7861 cctacaatcc atatttctga acctaagaca aaaccatctg aggtaatatg aactctaaat
     7921 ttatcaccat tagaagcaat tttattatat ggaacatatg tttcttcttt ggaatttgtt
     7981 ttttgtgttc tcgctgattc taaagagaac acaatttttc catcccactt tgcaattgga
     8041 tagtaccggt tatttgttaa gtcaccattg cttttttttt ggacttgtac taattcagtt
     8101 tccttatcat cttcttcgac tttaaatatt ctaatcaaag atcctggact agtttttact
     8161 actatttctt tgtcattatt tttgattggt ttaacgccaa agtctcgagc gttttcccaa
     8221 tctcttctaa atcctattac cttttggtca ccaatttgtg gtgcttctgt ataatcatca
     8281 taaccataat agccttgccc taaaactgga gaattttcat aatcactatt tgcacttact
     8341 tcgttgaaac atattaaact tagtaaaggt aaattaacga ttaaactcat cactaacttc
     8401 ttcttcattt tttcttccta acctccatta cttatgttta tttaataata gctagggtta
     8461 gtataaatga gatgttgtgt aaggtaaaga tgtttattaa aagtgactaa aagtaaagaa
     8521 ataatcctaa tagtagtttg gggatatttt gatttataca aaaaataatg tcattgaaca
     8581 cgctttatct aaaatagtct aacattctaa cgaaaataat tccaattatt ttcatatact
     8641 ggctagacat gctgtattag cttaatcaag aattacagcc gcagttttaa agacactcag
     8701 gttagtgtat tataaaaagc tggtgtgggt tacaaaggat ttcatatcac ttagattatg
     8761 tcataattag ttaagatgat gaatccttat ctaaaaacaa agcaaacttg tacgtttgcg
     8821 actttcgtga tctttaagct tacaaaagct gagtaaattg gtataatgat cattaaaaga
     8881 gctcatgcta tgatgtagac ctataaaagg agaaaaccat gacatttgaa gagattttgc
     8941 caggcttgaa ggccaagaaa aaatacgttc gtaagggctg gggaggcgct gaaaactatg
     9001 ttcagctgtt tgatagcatt gaacaaaatg gtgtggcact tgaggtgacg ccttactttt
     9061 tgattaacgt gtcaggagct ggcgagggct tttccatgtg ggcaccgact ccctgcgacg
     9121 ttcttgctac tgactgggta gaggtctatg actaagcggg tgctgatcac tggtgtgtca
     9181 tcgggcatag gactggcaca ggcgcgcctg tttttgagaa atggctttac tgtttatggg
     9241 gttgacaagg caaaaaagcc tgatttatca ggagattttc agtttttaca gttagatatt
     9301 acaggtgatt tagctgagct ttttgaggct gtgcctaggg ttgatgtgtt gtgtcatact
     9361 gcgggcgttc ttgatgccta taagcccttg cttgatacca cacaggctga ttttgaggct
     9421 ctctttcagg tcaatttctt tgcagctgtc cgcatcacgc gtcactattt ggcacagatg
     9481 ctgacagctc aatcaggtat tatcatcaat atgtgctcta ttgctagctt catggcaggt
     9541 ggcggcggag ctgcctatac ctccagcaag catgctctgg ctggttttac cagacagcta
     9601 gcgcttgatt atgccaaggc aggcattcag gtttttggca ttgcccctgg cgcagtgcaa
     9661 acagcaatga cagccacaga ctttgagcca ggtggcttag cccagtgggt ggctgatgag
     9721 actcctatcg gtcgttggct tagggctgaa gaaatagccg agctgaccat gtttttggca
     9781 tctggaaaag ctagcgccat gcagggagaa attgttaaaa ttgatggcgg ttggagctta
     9841 aagtgaaaca gcacatcgac ataaggccta gcaagatctg gcttgtctgt acagagggtg
     9901 acagttgata gctgtatcaa gcaatcttgt cacaggctaa gagggagctg atgaagtttt
     9961 ttccatgaag cctagtgcct agtaggtttg cttaatacag caggagccta cctgtctaga
    10021 ggattcgatc aatagaggtg ataacatgac tgcagaagaa ttatggtctc aataccagca
    10081 aatcaatcct ggtgttggtg atctagctga ggcctgggcc tttggagctg agcctgattt
    10141 attagcgcaa ttagtgctag aaggcactaa aacagctaca gcctctgcct atgactgata
    10201 tgagcctgat catgagccgc tttccaaaga gggcagctat gacgtgattt tggatagtag
    10261 ggatcaggcg atctgtatta tccagattac taaggttagt cttgttccct tcaaggacgt
    10321 gccagcagag catgcctata aggaaggaga gggtgataaa agcttggaag aatggcggct
    10381 gcttcatgag gcctttttca gaccttattt tgaagaggta ggcttacgct ttaccgagga
    10441 tagccttatt gtgttagagg agtttcagag ggtttaccct gaagctgcta aaaaggagaa
    10501 ataaatgaaa ttagcccttg ttggtacagg catgattgtc aaagaggttt tgcctgtttt
    10561 aaaggagatc aaaagcatag acttaatggc gattgtttca acgcctcgta gtcttgaaac
    10621 cgcagaggcg cttgctgacg cctttggcat tcaacaggcc agctgtcagc tagccgaggt
    10681 cctaaaaaat gaagaggtgg atacggttta tgttgccacc ccaaatcatt tgcattttga
    10741 agtggctaag caagcccttg aggctggtaa gcatgtcatt tgtgaaaagc catttaccat
    10801 gacagccaag gagcttgatg ctttaagcag cattgcaaga gctaagcagc tgatattatt
    10861 agaagctatt accaaccaat atttgccaaa cacccaattt attaaggatc acttgactga
    10921 gttaggagag attaagcttg tggagtgcaa ttattctcaa tattcctctc gttatgatgc
    10981 ctttaagcgt ggggagattg caccagcctt tgatcctaaa aagggtggag gggccttgcg
    11041 tgatttgaat atttataata tccatctgct cgttggctta tttggcaagc cccaaacggt
    11101 tcagtaccta gctaatatgg agcggcaggt tgacacctct ggtgttttgc tgatggatta
    11161 tgagcgattt aaggctgttt gtattggggc taaggattgc agtgcagaga ttgtctctac
    11221 gattcagggg aataaaggct ttctttctgt tttaggtgct cctaatgctg taccagagct
    11281 tttactagcc attcgaggtg agcaagcaag gaccgtcaac tttaaccacc cgtctcatcg
    11341 catgtacgat gaatttattg ccttttcaga tattatctct aataaggaca tggaaagggc
    11401 agagcaggcc ttggagcaca gcaaggcagt catggctgtt ttagagcagg cagcagcttc
    11461 gctagaaagc gatagctaag agtagctagt ggctacaagc taagtcatct tttttgctag
    11521 ctgtcttaag aagtgatgac ccttcttgtt ctatcagata caggtcttgt tcctgatgac
    11581 tcggagtctt tcaatcgcgg agcctaactg cttttttcat agtgaggggt ctaatttgca
    11641 gcttgctttg tttacgacat ctttgatact tagcgatgac aggcagctct agctagctgc
    11701 tttaaaaaag gagtcaaggt aggtaaggga gtttgtctga agctaaggac tattgcagca
    11761 ttcttgtttt ttctgcaaat taaggccatt tgtgctataa tgagatgatc tatgtacaaa
    11821 cggaggaagt cattatgcca aactacgcca ttatcctagc agctggaaag ggaacccgca
    11881 tgaaatcagg gcttcccaag gtgctgcaca aggtatcagg cttaagcatg ctggagcatg
    11941 tcctcaatag cgtctcagcc ctagctcctc aaaagcaact cacagtgatc ggtcatcagg
    12001 cagagcaggt acgtgccgtc ctaggtgatc aatcactgac agtggtgcaa gaggagcagc
    12061 taggaacagg ccatgcagtc atgatggcag aagaggagct atctggctta gagggacaaa
    12121 ccctagtgat tgcaggtgac acccccttga tcagaggaga aagtctcaag gctctgctag
    12181 actatcatat cagagaaaag aatgtggcaa ccattctcac agccaatgcc aaggatccct
    12241 ttggctatgg acgaatcatt cgcaatgtag caggagaggt ggtcaatatc gttgagcaaa
    12301 aggacgctaa tgaggcagag caagaggtca aggagatcaa cacagggact tatatctttg
    12361 acaataagcg cctctttgag gctctaaagc atctcacgac tgataatgcc caaggggagt
    12421 actacctaac cgatgtgatc agtattttca aggctggcca agaaagggtt ggcgcttacc
    12481 tgctgaagga ttttgatgag agcctagggg ttaatgatcg cctagcccta gc
//
LOCUS       DARYYD010000054        12428 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.055, whole genome shotgun sequence.
ACCESSION   DARYYD010000054 DARYYD010000000
VERSION     DARYYD010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12428
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.055"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(60..869)
                     /locus_tag="TV188_001575"
     CDS             complement(60..869)
                     /locus_tag="TV188_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1534910.1"
                     /translation="MDKLILGRYIPGNSIIHRLDPRSKLLAMIIYIIIIFWANNVVTN
                     LLLLAFTLLLIFLSQIKWSFFFNGVKPMIGIILFTTLFQVFFTQGGSVLFQLGIIKIT
                     SLGLSQAILIFMRFVLIIFFSTLLTLTTTPLSLSDAVEALLKPLVRFKVPAHEIGLML
                     SLSLRFVPTLMDDTTRIMNAQKARGVDFGEGNLIQKVKSIIPILIPLFASSFKRADAL
                     AIAMEARGYQGGDSRTKYRLLSWQLKDTLAIILVVILGIFLFCLKSPSRLT"
     gene            complement(862..1704)
                     /locus_tag="TV188_001576"
     CDS             complement(862..1704)
                     /locus_tag="TV188_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1534911.1"
                     /translation="MSIHFQNVSYTYQAGTPFEGRALFDVNLDIVDGSYTAFIGHTGS
                     GKSTIMQLLNGLHLPTTGKVTVAGKEITSQSKNKDIKPIRKQVGLVFQFPESQLFEET
                     VLKDVAFGPQNFGVSQKEAEALAREKLTLVGISEELFGKNPFELSGGQMRRVAIAGIL
                     AMQPDILVLDEPTAGLDPKGRKELMSLFKSLHQSGMTIVLVTHLMDDVANYADFVYVL
                     EAGKIILSGQPKAIFQHIDLLKEKQLGVPKVTAFAQRLAKQGFDLPYLPITLEELREV
                     LKHG"
     gene            complement(1680..2519)
                     /locus_tag="TV188_001577"
     CDS             complement(1680..2519)
                     /locus_tag="TV188_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEL1534912.1"
                     /translation="MSNIIEVKNLTFKYKQDQERYTLDDVTFHVKQGEWLSIIGHNGS
                     GKSTVVRLIDGLLKAEAGQIFVDGDLLTEDNVWDIRHKIGMVFQNPDNQFVGATVEDD
                     VAFGLENKGVSHQEMIERVHQALQLVGMEAFKDKEPSRLSGGQKQRVAIAGAVAMRPM
                     IIILDEATSMLDPKGRLELIRTIQSIRQEYQLTVISITHDLDEVALSDRALVMNNGRV
                     ESVSTPQELFARGNQLINLGLDIPFTTSVVNMLKKDGYPIQGIYLTEKELEEQLCQFI
                     SKM"
     gene            complement(2522..3064)
                     /gene="pgsA"
                     /locus_tag="TV188_001578"
     CDS             complement(2522..3064)
                     /gene="pgsA"
                     /locus_tag="TV188_001578"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003090075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEL1534913.1"
                     /translation="MIKKENIPNLLTLARIVMIPLFLLITSFSKTVGWHTFAAIIFAV
                     ASLTDYLDGYLARKWQVVTNFGKFADPLADKMLVMSAFIMLVGLELVPAWVSAVIICR
                     ELAVTGLRLLLVETGDKVLAAAMPGKIKTVAQMLSIIFLLCHWTVLGTVLLYIALLFT
                     IYSGYDYFKGASFLFKDTFK"
     gene            complement(3077..4081)
                     /locus_tag="TV188_001579"
     CDS             complement(3077..4081)
                     /locus_tag="TV188_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1534914.1"
                     /translation="MRETSLGELLRETRVGKNITLDEIEAKTGISSHYLLAMELDQFK
                     IIPEEKFGHFLKQYADIVGLDFDSLKRLYQLQVSFKKETGTPSVTQIVEEKLSKKRLQ
                     ENSYSEKIAQPEPSRTQPETLVIPVKTSLSSSKSAPTASHFKATDHRRTRETSASRLS
                     RYGNSAKTKKSAFPSALLGLIAVAIVGVIGFAVWKQFDKGQKAKEAEMSFLKSSQSSH
                     STASSSSEPKTVITTEGAENYLIANITKSKEAVDVTVSLTDAESSWISLTNSEIGEAG
                     MTLTKDNPTYSTTLPAETTESLLTLGVTKGVSVAIDGQPLDLSAMTSTDISYITLKIQ
                     "
     gene            complement(4131..5414)
                     /locus_tag="TV188_001580"
     CDS             complement(4131..5414)
                     /locus_tag="TV188_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1534915.1"
                     /translation="MTSLLKKDYPSIKETLHYGQLANGLRVYLIKKEGYSEKTAMLTA
                     RFGSLDTSFTVNCQRFDLPSGVAHFLEHKLFEDKDGNDIALTFTQLGSETNAFTTFDK
                     TSYFFSTVNEWQESLRLLQEFVAAPSFTEESVNREKHIITQEIEMYQDDPDYQAYSGI
                     LQNLFPNTSLAVDIAGTKESIRDITGSLLADSHAYFYHPSNMVLTIIGDIDIEEAFTA
                     IEAFQDSQPSQTQYDVQIAPLTYYPVIKSRSIDMDVATAKLAVGFRGQLMSSEYSLLT
                     YQVALRLLLAVLLGWTSKTYQDWYEKGKIDDSFDIEVDIQRDFQFVLISSDTSQPIAM
                     SNSIRKKISDFRCSRDVNEEHLELVKKEMYGDFMQSLDAIDQLASQFSLHLSEQETYF
                     DIPRIIETLALKDIIEIGSLFFEHAATSDFTVFPK"
     gene            complement(5416..6660)
                     /locus_tag="TV188_001581"
     CDS             complement(5416..6660)
                     /locus_tag="TV188_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEL1534916.1"
                     /translation="MKLIQGVQLHLIKNKTFKTNQITFRFSGDLNQKTVAKRVLVAQM
                     LATANDTYPTAKQFREKLAQMYGASLSTHVSTKGLVHIVDIDITFIQDQYAFYGEKLL
                     DEMIQFLKDILFSPLLSVAQYQPKLFDIEKRHLMTYVEADKEDSFYYSALKAKQLFYA
                     NDSLKLSKYGNTELIAKETAYTSYQEFHKMLNEDQIDIFILGDFDDYRMVQLLHQFPF
                     EGRRKKLDFFYLQQPVNVVNELVEQKQLNQSVLELAYHFPLVYGQAEYYALVVLNGLL
                     GAFTHSRFFTQIREKEGLAYSIGSRFDVYTGLFEAYAGIDRQHRTRALQLMVKELNDI
                     KMGRFSSSLVKKTKLMLKNNALLSEDNSKALIELEYMRSYIDPSYTLSSWLDEIDKVS
                     KLDIVRTANLLKLQAVYFLEGK"
     gene            6875..7288
                     /gene="yaaA"
                     /locus_tag="TV188_001582"
     CDS             6875..7288
                     /gene="yaaA"
                     /locus_tag="TV188_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEL1534917.1"
                     /translation="MTYTLFTDFITLQALLKEQGIIQSGGAIKGFLAQTEVFLNGQEE
                     QRRGKKLRVGDVITIPSQHIKIELVAPSQAEKTAYEAEKAEKERVAKMVKQMNQQAKK
                     AQTKQAATTKSKRGQATSAVKAKSNHQKPIRFPGL"
     gene            7290..8399
                     /gene="recF"
                     /locus_tag="TV188_001583"
     CDS             7290..8399
                     /gene="recF"
                     /locus_tag="TV188_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEL1534918.1"
                     /translation="MWIKELNLTHYRNYQQASAAFSPGLNVFIGDNAQGKTNFLEAIY
                     FLSVTRSHRTKSDKDLIYFDERDCSISGTLERLSGRVQLEILLSDKGRITKINTLKQA
                     KLSDYIGAMMVVLFAPEDLQLVKGSPNLRRKFMDIDLGQIKPVYLSDLSHYNHVLKQR
                     NAYLKSVHQLDNDFLSVLDEQLVTYGSRVMAHRLAFVQSLAKEANKHHQAISNGLEKL
                     SISYQASVSFEHQQEIYQQFMNQLKTTHQRDFLRKNTGVGPHRDDLVFYINDMNANFA
                     SQGQHRSLILSLKMAEVSLMKQLTGDNPILLLDDVMSELDNTRQTKLLGAVKKENVQT
                     FITTTSLEHLSQLPKDISLFKVNKGTIERDSIMID"
     gene            complement(8464..9327)
                     /locus_tag="TV188_001584"
     CDS             complement(8464..9327)
                     /locus_tag="TV188_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GRP family sugar transporter"
                     /protein_id="HEL1534919.1"
                     /translation="MEGILFALVPMFAWGSIGFVSNKIGGKPSQQTFGMTIGALLFAL
                     VVWLVVRPEMSMKLWIFGILGGIIWSVGQTGQFHAMQYMGVSVANPLSSGSQLVLGSL
                     IGVLVFHEWTKPIQFVVGTIALLLLIVGFYFSSKQDETNAASNQLHDFSKGFRALTYS
                     TTGYVMYAVLFNNIMKFDVLSVILPMAVGMVLGAAMFMSFKVSFDQYVIKNSVVGLLW
                     GVGNIFMLLAASKAGLAIAFSFSQLGAIISIVGGILFLGETKTKKEMRWVITGILCFI
                     VGAILLGIVKS"
     gene            complement(9498..11927)
                     /locus_tag="TV188_001585"
     CDS             complement(9498..11927)
                     /locus_tag="TV188_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEL1534920.1"
                     /translation="MMILTDEQRQRIAEEEYEKHTVGSPVLIDDDNSEFSIGYVSQIE
                     DSISGFQAYVVTDVKLPPHPTKADYAQVKHVTMLYRGSTGPDQWQKHPVDVVADWVGN
                     DLPMAMRILLPDQTPTKGTAQLRKAATFTNKTLKQYPNATFEFYGHSLGSMTVQYGVT
                     SVSDKNLSRISGVYIYNGPNTYRVLNEYQRKRAKLLHDRIYNYVDPHDIIGMGFDQKE
                     GAVGQVFVVNTKKVNDIVLQHMWHGYQYDQYGNMTDVNGRFVHANVLLPIDIDSDNRL
                     DTKVEELYLGFRNYFDSSTSARYGVLSDKQTIVINAGVLTNLAQNLQSSISGDLQTIR
                     HITEKCQAKNDAIKDSFEERKKRVSENIKALLATNGLTDTFNSLQSSLERLVGQQDLF
                     DMLSHSASLDYPFSYDEIPYVNNNRLNLAMYDSELASLNTKSLQLASSAQHEKSGWID
                     SIIGRSTLLKSWQIIDEASRQLLKESDKTFEGTGLRESKVDGISDSLKEVFSVELQDI
                     IELEKMIINTSELILGVSQNVTATDNWLGNSLKNGQFQGSADVVCVPSSYDAYLERTG
                     LLDDVRDILQAFDEQVEQKSRDYSRKVASVYASTFSRLFDTLDYWTTEVNIFKNIVTV
                     LERRFSDRVYVERTEIKDETSTTTRSYWGNLGALYPCRIRSGIASARAEVCPLVPALT
                     DTIQRVNTARHRLQNLHGDLSRLIEKGVYSALDLDDIITSQKMVGRLLDKIIVELSFV
                     KATIEASMSGQAASAMVNHLALLLKRLGYFSQLVADCFGTQVTKVPNKAPARASHKVK
                     RFSLNNPLALQ"
     gene            12149..12232
                     /locus_tag="TV188_001586"
                     /pseudo
     CDS             12149..12232
                     /locus_tag="TV188_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002932394.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12260..>12428
                     /locus_tag="TV188_001587"
     CDS             12260..>12428
                     /locus_tag="TV188_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEL1534921.1"
                     /translation="MIRLIDRYGLAIVQKGKNSYYSPELKQEIIDKVLIDGQSQKQTS
                     LDYALPNSSMLS"
BASE COUNT         3839 a         2660 c         2323 g         3606 t
ORIGIN      
        1 ttgttattat taataaattc tagttgctac agcctaacaa aggggctgct gtaatatagc
       61 taggtgagcc ttgagggact ttttagacag aaaaggaaaa tccccaaaat gactaccaaa
      121 ataatggcta gagtgtcttt taattgccag cttagcaggc ggtattttgt tcgactgtca
      181 ccgccttgat agcctctagc ctccatagcg atcgctaaag cgtcagctct tttaaagctt
      241 gaagcaaaaa gaggaatcaa aatagggata atcgacttta ccttttgaat aagattgcct
      301 tctccaaaat caacacctcg cgctttttgc gcattcataa tacgagttgt atcgtccatc
      361 aaggttggaa caaaccgtaa gctcaaagat aacatcaaac cgatctcatg ggcaggtacc
      421 ttaaacctaa ctaaaggctt caacagcgct tcaacagcat cagataagct tagtggggtg
      481 gtggttaggg ttaacagcgt ggaaaagaaa ataatcaaaa caaatcgcat gaaaatcaaa
      541 atggcttgac ttaatcccaa gcttgttatc ttaattattc caagctgaaa aagaactgat
      601 cctccctgtg taaaaaaaac ttgaaaaagc gttgtaaata ggataatacc aatcataggc
      661 ttaacaccat tgaaaaagaa agaccatttt atctgtgaca agaaaatcag cagcaaggta
      721 aatgctaaca gcaaaagatt agttaccaca ttattggccc aaaaaataat gataatatag
      781 ataatcatag caagcagctt gcttcttgga tcaagccgat gaataattga attcccagga
      841 atatagcgac caagaatgag tttatccatg ctttaatacc tctcttaatt cctccaaagt
      901 aatgggtaaa tagggtaaat caaagccttg cttagccagg cgttgggcaa aggctgtcac
      961 cttagggaca cctaattgtt tttcttttag caaatcaatg tgttgaaaaa tagcctttgg
     1021 ctgacctgat aagatgattt taccagcttc aaggacataa acaaaatcag cataattagc
     1081 aacatcgtcc atcagatgtg tcaccagtac aatggtcatg cctgattgat ggagcgattt
     1141 aaaaagactc attaattcct ttcgcccttt gggatcaagc ccagcagtag gctcatctaa
     1201 caccaaaata tccggctgca tcgcaagaat acccgcaata gcaaccctgc gcatctgccc
     1261 accagaaagc tcaaatggat ttttaccaaa tagttcctct gaaatcccta ctagggttaa
     1321 tttttcacgc gctaaagctt ccgcctcttt ctgagaaaca ccaaaatttt gtggtccaaa
     1381 ggcaacatcc ttcaaaaccg tttcctcaaa aagctggctc tcaggaaatt gaaagactag
     1441 accaacctgc ttacgaatag gcttaatatc tttatttttt gactgactag ttatctcctt
     1501 gcctgctacc gtaaccttgc cggtggtcgg cagatgcaag ccatttaaga gctgcataat
     1561 cgttgacttg cctgagccag tatgaccaat aaaagccgta taagagccgt ctacaatatc
     1621 aagattaacg tcaaaaaggg cacgcccctc aaagggtgtc cctgcttgat acgtgtagct
     1681 tacattttgg aaatgaattg acatagctgt tcctctaatt ccttttctgt gagatagatt
     1741 ccctgtatag ggtagccgtc tttttttagc atattaacaa cagaggttgt aaaaggaata
     1801 tctaaaccta gattgatcaa ttgattgccc ctagcaaata gctcctgtgg agtcgagaca
     1861 gactcaacac gcccattgtt catcaccaaa gctcgatcac taagagccac ctcatcaaga
     1921 tcatgtgtaa tagatataac agttagttgg tattcttgtc taatagattg aattgtccga
     1981 atcaactcca gacgcccctt tggatccagc atactggttg cttcatctaa aatgatgatc
     2041 attggccgca tggcaacagc acctgcaata gcaacccgct gcttttgacc acctgataat
     2101 ctggaaggct ccttatcctt aaaagcctcc ataccgacca gctgcaacgc ctgatgaaca
     2161 cgctctatca tctcctgatg ggaaacacct ttgttttcaa gaccaaaagc aacgtcatct
     2221 tcgacagttg caccaacaaa ttggttatca ggattttgaa ataccatgcc aattttatga
     2281 cgaatgtccc agacattgtc ctctgtaaga agatcaccat caacaaaaat ctggccggct
     2341 tctgctttca atagcccatc aattaaccta acaacggttg acttgcctga gccattatgc
     2401 ccaatgatag acaaccactc gccttgtttc acatgaaacg tcacatcatc tagggtatat
     2461 cgctcctggt cctgcttata cttaaatgta agattcttaa cttcaataat atttgacatt
     2521 gttatttaaa ggtatcctta aaaagaaagc ttgctccttt gaaataatcg taacctgaat
     2581 aaatcgtaaa caatagagca atatacagca aaacagtgcc taaaacagtc caatgacaca
     2641 gtaaaaagat gatggaaagc atctgtgcta ctgttttgat cttaccaggc atagcagctg
     2701 ctaggacctt atctccagtc tcaaccaata gcaaacgaag tcctgtaaca gctagctcac
     2761 gacagataat aaccgctgac acccaagccg gtaccagctc taagcccact aacataataa
     2821 aagcactcat gacaagcatc ttgtctgcca atggatcagc aaatttacca aaattagtaa
     2881 caacctgcca cttacgtgca aggtaaccat ctaaataatc ggtcaggctt gccactgcaa
     2941 aaataatcgc tgcaaaggta tgccaaccga ctgtctttga aaaagaggtg atcaacaaaa
     3001 acaatggaat catgacgata cgggcgagag ttaacaaatt gggaatattt tcttttttga
     3061 tcatgcttat accttattat tgtatcttca gtgtgatata gctgatatca gtacttgtca
     3121 ttgctgataa atctaggggc tgaccatcaa ttgctactga aacacccttt gttacgccta
     3181 gtgtcaacaa ggattctgtt gtctcagcag gcaaggtagt agaataagtc ggattgtcct
     3241 ttgttagggt cataccagcc tcaccaattt ccgaattagt gagggaaatc caactgctct
     3301 cagcatcagt cagtgacact gtaacatcaa cagcttcttt tgatttagta atattagcaa
     3361 tcaagtaatt ctctgcgccc tctgttgtga tcaccgtctt aggctcagat gagctggacg
     3421 ctgttgagtg actgctttgt gatgacttaa gaaaagacat ctcagcctct tttgcttttt
     3481 gacctttatc aaattgcttc caaacagcaa aaccaataac accaacaata gccacagcaa
     3541 taagacctag taaggctgat ggaaaggctg attttttcgt tttagcacta tttccataac
     3601 gacttagcct tgaagcactg gtctctctag tccgtctatg gtcagtagcc ttaaagtgac
     3661 tagctgtagg agctgatttg cttgaggata gtgacgtctt gacaggaatc actagggttt
     3721 ctggttgagt ccttgaaggc tctggttgag ctattttttc agaatagcta ttctcttgta
     3781 gccttttttt gctgagcttt tcttcaacga tttgtgtgac tgatggtgta cctgtttcct
     3841 ttttaaagct cacctgcagc tgatacaagc gttttaagct atcaaagtct aagccaacaa
     3901 tatcagcata ttgctttaga aaatgaccaa acttttcttc tggaatgatt ttgaactggt
     3961 caagctccat tgccaataga taatgcgagg aaatgccagt tttagcttca atttcgtcta
     4021 atgttatgtt ttttccgaca cgtgtttctc ttaataattc accgagactt gtttctctca
     4081 tacgagtacc tcaaaaatat tgtaataaga ccattataac agattttaag ctatttggga
     4141 aagactgtaa aatctgaagt agctgcatgc tcaaaaaaca agcttcctat ttcgataata
     4201 tcctttaaag ctagggtctc aataatccta ggaatatcaa aataggtctc ttgctctgat
     4261 aaatgaaggc taaattggct tgccagctga tcaatagcgt ctaagctttg cataaaatcc
     4321 ccatacattt cctttttcac tagctctaag tgctcctcat taacgtctct tgagcatcta
     4381 aaatcggaaa tcttttttct aatgctgtta gacattgcaa taggctgact agtatctgaa
     4441 gaaatcaata caaattggaa atccctttga atgtcaacct ctatatcaaa ggagtcgtct
     4501 atcttgccct tttcatacca atcctgatag gtttttgacg tccagccaag gagcaccgct
     4561 aggagcagtc taagagctac ctgataggtg agtagagaat actcgcttga cattagctga
     4621 ccgcgaaagc cgactgctaa tttggcagtc gcaacgtcca tatcaataga tctagacttg
     4681 atcacagggt agtaggtcaa tggagctatc tgtacatcat actgcgtctg acttggttga
     4741 ctatcttgaa aggcttcaat agctgtaaag gcttcttcaa tgtcaatatc gccaataatc
     4801 gttaagacca tgttagaagg gtgataaaaa taagcatggc tgtcagccaa taaagagcct
     4861 gtaatgtccc tgatagactc cttggtccca gcaatatcaa cagctaagct ggtattggga
     4921 aagaggttct gtaagatacc actgtaagcc tgataatcag gatcgtcctg atacatctca
     4981 atttcttgag tgataatatg tttttcacga ttaaccgact cctctgtaaa gctaggagct
     5041 gctacaaatt cctgcaaaag tctcagactt tcttgccatt cattgacagt tgaaaagaaa
     5101 tagctcgttt tatcaaaggt tgtaaaggca tttgtttctg atcctaactg tgtaaatgta
     5161 agagcaatat cattaccatc tttatcctca aatagcttgt gctctaagaa atgagcaaca
     5221 cctgacggca agtcaaacct ttgacaattg actgtaaagc ttgtgtcaag agaaccaaaa
     5281 cgagcagtca gcatagctgt tttctcagaa tagccctctt tctttatcaa ataaaccctt
     5341 aaaccatttg ccaattgacc gtagtgtaag gtctctttaa tgctgggata gtcttttttc
     5401 agtagtgacg tcatcttatt ttccctctaa aaaatataca gcttgcagct tgagtagatt
     5461 agctgtcctg acaatatcta gcttgctaac cttgtcaatc tcgtcaagcc aacttgacaa
     5521 agtataggaa ggatctatat aagatctcat gtattccagc tcaatcaagg ctttactatt
     5581 atcctcagat agcaaggcgt tattttttag cattagcttt gttttcttga caaggctgct
     5641 tgaaaagcgc cccatcttga tgtcattgag ctctttaacc attagctgca gggctcttgt
     5701 ccggtgctgt ctatctatgc cagcataagc ctcaaataag cctgtgtaaa catcaaatcg
     5761 actaccaata ctataggcca gcccctcctt ctcacgaatt tgggtaaaga agcgagagtg
     5821 tgtaaaggct cctaatagac catttaacac aactaaggca taatactctg cttgcccata
     5881 aaccagcgga aaatgatagg ctagctctaa aacagactga ttaagctgct tttgctcgac
     5941 caattcgttg acaacattga caggctgctg taaataaaag aaatctagct ttttcctgcg
     6001 tccctcaaag ggaaattggt gtaacaattg taccatacga taatcatcaa aatcaccaag
     6061 aataaaaata tcaatctgat cctcattcaa cattttatga aattcttgat agcttgtgta
     6121 ggctgtttct ttagcaatta actcagtatt accatatttt gacagcttca ggctatcatt
     6181 agcataaaat aattgcttgg cttttagggc actataataa aaggaatcct ccttatctgc
     6241 ctcgacatag gtcatcaaat gtcttttttc gatgtcaaat agtttgggct ggtactgagc
     6301 cactgataac aaaggagaaa aaaggatatc ctttagaaat tgaatcattt cgtctagaag
     6361 cttctctcca taaaaagcat actgatcctg aataaaggta atgtcaatat ccacaatatg
     6421 aaccaaaccc ttggttgaca catgagttga caggcttgct ccatacattt gtgctaattt
     6481 ttctctaaat tgcttggcag taggataggt atcgttagcc gttgctaaca tttgagctac
     6541 taagactcgc tttgctaccg ttttttgatt caaatcacct gaaaagcgaa acgttatctg
     6601 attcgtttta aatgttttgt tttttatcag atgaagctga actccctgaa taagtttcat
     6661 aatatttcct tattaataaa tgtgtgatct ctagaattat accattttta tcgctattcg
     6721 ttgagtgtta acatcagtct ggtagcctat tttgactctt tatcaaaatg ctatcctgtg
     6781 gctatagtct agactttaga aggtcagcat ttcagcatta ttatttagtg gctttttatg
     6841 ctataatgac ttgaatgaca aattggagat gactatgaca tacacactat ttactgactt
     6901 tattacccta caagctttat taaaggagca aggtattatc caaagtggtg gtgccattaa
     6961 aggtttttta gctcaaacag aggttttttt aaatggtcaa gaggaacaac gacgtggcaa
     7021 gaagctaaga gtcggtgacg tcatcaccat tccatcacag cacatcaaga ttgagcttgt
     7081 agcgcctagt caggccgaaa aaacagccta tgaagctgaa aaggcagaaa aagagcgagt
     7141 tgctaagatg gttaaacaaa tgaatcaaca ggctaaaaaa gcacagacca agcaagcagc
     7201 tactaccaaa agcaagcgtg gtcaagctac ctcagctgta aaagctaagt ctaatcacca
     7261 aaagcctatt cgcttcccag gattgtagca tgtggatcaa agaactaaac ctcacccatt
     7321 accgtaatta tcaacaagcc tcagcagcct tttcaccggg cttgaatgtt ttcattggtg
     7381 acaatgcgca gggcaagaca aattttcttg aagctattta ttttttgtca gtaacaagaa
     7441 gtcatcgcac caaatctgat aaggacttaa tctactttga cgaaagggat tgctctatat
     7501 ctggaactct tgagcgcctt agtggtcgtg ttcagctaga aatactgctg tctgataagg
     7561 gacggatcac caagattaac accctaaagc aagcaaagct ttctgattat atcggagcaa
     7621 tgatggtggt cctctttgct cctgaggatc tacagctggt caaaggctct cctaatctta
     7681 gacgaaaatt tatggacatt gacttaggtc agataaagcc tgtttactta tcagatttgt
     7741 cacattacaa tcatgtccta aagcagcgaa atgcctatct caaaagtgtt catcagcttg
     7801 ataatgactt tttatctgtg ttagatgagc agctggttac ctacgggagt cgtgtaatgg
     7861 cgcatcggtt ggcgtttgtt caatcactag caaaagaggc aaacaagcat catcaagcta
     7921 tctctaatgg cctagagaag ctttcgatct cctatcaagc ctctgtgagc tttgagcacc
     7981 agcaagagat ttatcagcaa ttcatgaacc agctcaaaac cactcatcaa agagatttct
     8041 tgagaaaaaa tactggtgtt ggcccccacc gcgatgatct ggttttttat attaatgaca
     8101 tgaacgctaa ttttgctagt caaggccagc atcgtagcct gattttatca ctgaaaatgg
     8161 cagaggttag tctgatgaag caattaacag gtgacaaccc tattcttcta cttgatgatg
     8221 ttatgagtga gttagacaat accagacaaa caaagcttct gggagctgtc aagaaagaaa
     8281 atgttcaaac ctttatcaca acaactagct tagagcattt gtctcagcta cctaaggaca
     8341 ttagtctctt taaggttaat aaaggaacaa tagaacgaga ttctatcatg attgattaac
     8401 tgagcaaact aaaaaaaggg caccttaata gtgacccttt ttacggttaa attagttgat
     8461 actctatgat ttgacgatac ctaagaggat agcgccaaca ataaagcaaa ggatacctgt
     8521 aatgacccag cgcatctctt ttttggtttt tgtctcacct aagaataaaa tacctccgac
     8581 aatagagata atagcgccca attgtgaaaa gctaaaagca atcgccagac cagcctttga
     8641 ggctgctagc agcatgaaga tatttccaac tccccaaagc aagccaacaa cactattttt
     8701 gataacatac tggtcaaacg ataccttaaa cgacataaac atggctgcac caagcaccat
     8761 tcccactgcc atcggtaaaa taaccgacaa cacatcaaat ttcataatgt tattgaacag
     8821 cacagcatac atcacatagc cggttgtcga gtaggttaag gctctaaagc cctttgaaaa
     8881 atcatgcaat tgattacttg ctgcattcgt ctcgtcctgc ttgcttgaaa aataaaaacc
     8941 aacaatcaaa agaagtaagg caatcgtacc aacgacaaat tgaataggct tggtccactc
     9001 atgaaagacc agcacaccaa tcaggctacc taaaactagc tgagaaccac tagacaaggg
     9061 atttgctact gaaacaccca tatactgcat ggcatgaaat tgcccagtct gaccaacaga
     9121 ccagataata ccacctaaaa tcccaaaaat ccagagcttc atagacatct caggtctgac
     9181 tactaaccaa acaactagag caaatagtaa agctcctatg gtcattccaa aggtctgctg
     9241 tgagggttta ccgccaattt tattactaac aaagccaata cttccccatg caaacattgg
     9301 gacaagtgca aataaaatac cttccaaatt tacatctcct ttacaataag ttgacacatg
     9361 atgttaacga taaaagtgct ttcatacgga gaattattat agcctatttc cttagaaaat
     9421 acaataacat gatgtaaaaa atcatctgct cacacgcttc tccctaaaaa ggtgtcaaag
     9481 tagctgacag agcttattta ctgcaatgct agaggattat ttaatgaaaa ccgtttgacc
     9541 ttatggctgg ctctagctgg agctttgtta gggacttttg tgacctgagt tccaaagcaa
     9601 tcagcaacta gctgactgaa atagcctaag cgtttgagga gtagagcaag atgattaacc
     9661 atagcactag ctgcttgacc ggacatgctt gcttctatgg tagctttgac aaaggatagc
     9721 tcaacgatga ttttatccag cagtctgcca accatctttt gactagtgat gatgtcatct
     9781 aaatcaagag cgctgtaaac tcctttttcg atcaatcgac tgagatctcc atgcaagttt
     9841 tgaagccgat gccttgcggt attgactcgc tgtatcgtat cagtcaatgc cggtactaga
     9901 ggacatacct cagctctggc agaagcaata ccggatctta tgcggcaagg atataaagca
     9961 cccagatttc cccaatagct ccttgtcgtt gtagaggttt catctttgat ttctgttcgt
    10021 tcaacataaa ccctatctga aaaacgtctc tctaatactg tcacgatatt cttaaagata
    10081 ttcacctcag tagtccaata atcaagtgta tcaaatagcc ttgaaaaggt tgacgcataa
    10141 acagaggcaa cctttctgga atagtcccga ctcttttgtt ccacctgctc atcaaaggct
    10201 tggagaatat ctctgacatc atctaaaaga cctgttcttt ctaggtaagc atcatagctg
    10261 cttgggacac agacgacatc agcacttcct tgaaattgac cattttttag gctgttgcct
    10321 agccagttat ctgtagctgt gacattttgt gataccccta ggatcagctc actggtattg
    10381 attatcattt tttccagctc tatgatatcc tgtaattcca cgctaaatac ctcttttaag
    10441 gaatcgctaa taccgtcaac tttactttca cgtaaacccg ttccttcaaa ggtcttatca
    10501 ctctccttca atagctgacg actggcctca tcaataatct gccaagattt caaaagtgtc
    10561 gagcgaccga taatactatc aatccagcct gacttttcat gctgagcaga tgaggcaagc
    10621 tgaagcgatt ttgtgtttaa gctcgctaat tctgaatcat acatggccag attgaggcga
    10681 ttattattca catatgggat ctcatcatag gaaaagggat agtctaggct agccgaatga
    10741 gacagcatat caaacaagtc ctgctgacca actaatctct ccaaagaact ttgcaggcta
    10801 ttaaaagtat cggttaggcc atttgtagca agcagggctt tgatgttttc tgaaactcgc
    10861 tttttcctct cttcaaagga gtcttttatg gcatcatttt ttgcctgaca tttttcagta
    10921 atgtggcgaa tcgtttgcag gtcgcctgat atagaggatt gaaggttttg tgcaaggtta
    10981 gtcaggacac cagcattgat gacaatcgtt tgcttatcag aaagcacacc gtaccgagcc
    11041 gatgttgacg aatcaaagta atttctaaag cctaagtaca gctcctctac cttagtgtct
    11101 aatcggttat cgctgtcaat atcaataggc aacaggacat tagcatgaac aaaccggcca
    11161 tttacgtctg tcatgttgcc atattgatca tactgatagc catgccacat atgctgtaag
    11221 actatatcat tgaccttttt tgtattgaca acaaagacct gaccgactgc tccctccttt
    11281 tggtcaaagc ccataccaat gatgtcatgc ggatccacat agttgtaaat gcggtcatgc
    11341 aagagctttg cacgttttct ttgatactca ttaagcacac gataggtgtt ggggccattg
    11401 tagatataga ctccagagat acgagataag tttttatcac taacagaggt aacaccgtac
    11461 tgaactgtca tggagcctag cgaatgacca taaaactcaa atgttgcgtt agggtattgc
    11521 tttaatgtct tattggtaaa ggttgctgcc tttcggagct gagctgtccc tttagttggt
    11581 gtctggtccg gtaaaagaat gcgcatagcc ataggcaaat cattgcctac ccaatctgca
    11641 accacatcta ctgggtgttt ctgccactgg tctgggccag tagagccccg gtacagcatg
    11701 gtgacatgct tgacctgagc atagtctgcc ttggtaggat gagggggaag cttgacatct
    11761 gtcacgacat aggcttgaaa acctgatatc gaatcctcta tctgagacac ataaccgatg
    11821 gaaaactcag aattatcatc atcaattaaa actggtgaac ctactgtatg tttttcatac
    11881 tcttcctcag caatccgttg tctctgttcg tctgtcagga tcatcatttt cactctcctt
    11941 ttagtagttt ttctaacttt tctgagcgat aattactagc gatctctaaa tttctttcta
    12001 aatcatatct actaaggcga acccttaaat aagtatctgg atcatcattg ataatcaggt
    12061 gaatagaaaa acctcccctg gcttgaatga actgtgaact gccccccaaa agttagacat
    12121 aaaatctaac aattgggggg ctatttttat gacattgagt tatgaagaca aggttcaaat
    12181 ctatgagcta cggcacattg gaaagtccat taaatgctta tcagaaaagt ttagtattgt
    12241 agaatctgac ctcaaataca tgattcgcct gattgacagg tatgggttag ccattgtcca
    12301 aaaaggtaag aatagttatt attctccaga actgaagcaa gagataatag ataaagttct
    12361 gattgatggt caatctcaaa aacagacgtc cttagactat gctttaccaa attctagtat
    12421 gctttcaa
//
LOCUS       DARYYD010000055        12358 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.056, whole genome shotgun sequence.
ACCESSION   DARYYD010000055 DARYYD010000000
VERSION     DARYYD010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12358
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.056"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(43..2631)
                     /gene="hylB"
                     /locus_tag="TV188_001588"
     CDS             complement(43..2631)
                     /gene="hylB"
                     /locus_tag="TV188_001588"
                     /EC_number="4.2.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192884538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HEL1534922.1"
                     /translation="MATGTEKKHQEKLYIPKLKVNQIKLELFYEAGHGQVVFDNLSLR
                     EAGDKPSDDIKIASHYLEEQIVLPLNKHYLMEMADYHYQIAAESSNIVRVENGLLIPL
                     AQGKTLLEVLDQEGQRVATVPVEILAAEAPQTTSLITKWCEVILGAENFDRSSPAMVA
                     LNQKLDDSVTKNLADLTKDQKSTYLWSDLADLHQSSHMTATCRRLEEMAKQVSSLASR
                     YYQDKELIRLIKDKLAWLTLNYYHPQKDIEGKANWWDFEIGTPRAIVNTLAFIYPYVT
                     QEEIKRYTKGISHFVPNPRQFRLTLVNPFKAIGGNLVDMGRVKIIEALLKHDKKALQD
                     SIAALDTLFAFQPKGSRGEGFYEDGSYIDHTNVAYTGAYGNVLIDGLSQLVPLLQLLA
                     TSLDQQKLEVMTHWIEQAFLPLMVHGELMDMSRGRSISRENASSRQAALEALRGMLRL
                     AEALPEQAKIRIKGKIKAVLAFHNQETILESLSSYYDMKLFKELLEDTTIQASPVKSY
                     LSLFNQMDKLAYYNAEKDFAFALSMHSNKTLNFEAMNDENTRGWYTGDGMFYLYNSDL
                     GHYSDHFWPTVNPLKMAGTTEAEVRREDVTVAYLKKLTNDYKEKAKEKAGMSTLPSSF
                     VGAIKAGDKTALAVMDFQNWDRTVSAKKSWTILDDQIVFLGTAITSQTHQAVTTTIDQ
                     RKENPDNSYTLFINGQETALTEEILYRDDVTSLLLLSKDGQANIGYLFAKPTALALSR
                     KVQSGCWSEINTNSNNKDLISQSFITISQTHSQASDSYAYTLLPNISKADFDKVCSEA
                     RIEVLRNDSKLQLIHDKKQGLLAVVKYNQAKEVVNGQLSLEKSGLYLYQKVGNDFKQL
                     SFKALS"
     gene            complement(2577..3230)
                     /locus_tag="TV188_001589"
     CDS             complement(2577..3230)
                     /locus_tag="TV188_001589"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534923.1"
                     /translation="MKQRKKLSSSVCSSIILACLFRAPTVLAEEKTAAKAISKELQRV
                     KKAPLKTEEASQESSPDTQDASSVATESSLGEQLILTGDNLLKNPQFDQTSPAQEHQS
                     TSLWSKESANDWKDYKDASKSQGCPKIAVSDNKLTMTSDGNQRFRGCVHQTVAINPDK
                     QYLLTFDIETKDKTGQAFARIIEEIKQGSGAAKEQRLWLRWQQELRKNTKKSFISLS"
     gene            complement(3270..3899)
                     /locus_tag="TV188_001590"
     CDS             complement(3270..3899)
                     /locus_tag="TV188_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEL1534924.1"
                     /translation="MRKSEIMLRLKANKLALVVRGASKKEAMACSLAGIEGGIKTIEV
                     AYTNPFASQVIAGLREAVGNDPEILIGAGTVLDDVTARLAILAGAQFIVSPSFSRQTS
                     RLCHRYAIAYIPGCMTIEEVVTALESGAEMVKVFPGATVGMSFIKAIKSPLPQVDVMV
                     TGGVTVTNVSDWFAAGAQVLGVGGEFNQLAAQGQFQAITARAADYMSSC"
     gene            complement(3901..4902)
                     /locus_tag="TV188_001591"
     CDS             complement(3901..4902)
                     /locus_tag="TV188_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEL1534925.1"
                     /translation="MTKVLLVGEPLIRISPSHFQTLGHACQAQLYYGGSEVNIARTLS
                     GFRAESSLLTALPDNQVGRSVEAFLKQSGVATEHVQWCGDRVGIYYLENGFGCRPSQV
                     AYDRSASSFSLLGPKDLDYGKLFEEVTHFHFSGITLALGKVSQDLVEQLAIEAMKRQV
                     CVSFDLNFRSSMISVREAKTLFSHFAQYADLIFGMEPLMCNQADHAMFDRAKAGQGAV
                     KERLAALYEAYHLKAIFHTERHIDDQGINHYLAYAYDGQLHRSIELSTPVLQRVGSGD
                     AFVAGCLYQLMRGQAIAAALDFAAATASLKCTVADDQLFVPVSQVDRVMKGNREVRR"
     gene            complement(4935..5576)
                     /locus_tag="TV188_001592"
     CDS             complement(4935..5576)
                     /locus_tag="TV188_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEL1534926.1"
                     /translation="MKIALINENSQAAKNSIIYETLVSVTNKHGYEVFNYGMYGKEGE
                     SQLTYVQNGLLASILLTSKAADFVVTGCGTGVGAMLALNSFPGVTCGFASEPTEAYLF
                     AQINGGNALSIPFAKGFGWGAELNLTLMFERLFAEPMGGGYPKERAIPEQRNARILSE
                     LKAVTYRSLLEVLKEIDQDFLKETISGEHFQHYFFANAEPSDLVDYLREVLQQ"
     gene            complement(5611..6405)
                     /locus_tag="TV188_001593"
     CDS             complement(5611..6405)
                     /locus_tag="TV188_001593"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEL1534927.1"
                     /translation="MEHFFSLEGKIALITGASYGIGFEIAKAYAMAGAKIVFNDIKQD
                     LVDQGLAAYREFGIKAHGYVCDVTDEVGIQEMVAQIEKEVGIIDILVNNAGIIKRTPM
                     LEMTAKDFRQVVDIDLNAPFIVSKAVLPSMIKKGHGKIINICSMMSELGRETVSAYAA
                     AKGGLKMLTKNIASEFGEANIQCNGIGPGYIATPQTAPLRERQADGSRHPFDQFIIAK
                     TPAARWGTPADLAGPAIFLASEASNFVNGHILYVDGGILAYIGKQP"
     gene            6714..7148
                     /locus_tag="TV188_001594"
     CDS             6714..7148
                     /locus_tag="TV188_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEL1534928.1"
                     /translation="MISIIVIGHGHFASGIVSSLELIAGKQEGITAIDFTAEMTAADV
                     HERLSVVLQSKTQALMLCDLLGGTPFKVAATLMEELSESTLDVLSGLNLAMLIEAVFA
                     RQEQLDLEQIVAKLLTTAKEGISNWKSLSGEADEADLDEGGI"
     gene            7148..8347
                     /locus_tag="TV188_001595"
     CDS             7148..8347
                     /locus_tag="TV188_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEL1534929.1"
                     /translation="MTRQIKEVTLEPLIQAEVYSQQPYLTKADIEAAILLALKQIRLN
                     MDYFGTDFPRPATKDNCYPIMDNTEWTNGFWTGCLWLAYEYTGNDTIKSLAQANDLSF
                     LERVTKDIELDHHDLGFLYSPSCMAEWKLLKTPEARQAALKAADKLIERYQEKGGFIQ
                     AWGQLGKAEDYRLIIDCLLNIQLLFFASQETGDDRYRQMAINHFYASANNVIRDDASA
                     YHTFYFDPETGDPIKGVTRQGYSDDSAWARGQAWGIYGIPLTYRFLKDPQLIALFKGM
                     THYFLNRLPKDQVSYWDLIFEDGSGQSKDSSATAIAVCGIHEMLKHLPENDPDKKAYQ
                     AAMHCMLRSLIDSYANKDIKPGAPLLRHGVYSWHSGKGVDEGNIWGDYYYLEALLRFY
                     KDWTPYW"
     gene            8393..8881
                     /locus_tag="TV188_001596"
     CDS             8393..8881
                     /locus_tag="TV188_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEL1534930.1"
                     /translation="MTPPNIIMTRVDERLIHGQGQLWIKFLNCNTVIVANDAVAEDKI
                     QQSLMKPVVPSSIAMRFFSIQKVIDVIHKASPAQTIFIVVKDLEDIKRLVEGGVPIKE
                     VNLGNIHKTDDKIAITQFISLGDKDKAIIRTLTHDHHIVFNTKTTPAGNGASEVNILD
                     YI"
     gene            8896..9675
                     /locus_tag="TV188_001597"
     CDS             8896..9675
                     /locus_tag="TV188_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEL1534931.1"
                     /translation="MDINLLQALLIGLWTAFCFSGMLLGIYTNRCIILSFGVGIILGD
                     LPTALSMGAISELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVTPEAALALST
                     PIAVAIQFLQTFTYTAFAGAPETAKKQLQKGNIKGFTFAANGTIWAFAVIGLGLGLLG
                     ALSMDTLLHLVDYIPPVLLNGLTVAGKMLPAIGFAMILSVMAKKELIPFVLIGYVCAA
                     YLQIPTIGIAIIGIIFALNEYYNKPKHATTAEQGGQQDDWI"
     gene            9662..10483
                     /locus_tag="TV188_001598"
     CDS             9662..10483
                     /locus_tag="TV188_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEL1534932.1"
                     /translation="MTGSNKLTKRDYLKTALRAFFLQNGFNYSNYQGIGYANVVYPAL
                     KKHFGNDKTGLYKALENNCAFYNTNPHFLPFITSLHLVMLENNRPEEETRNIKMALMG
                     PLAGIGDTLTQFCLAPLFSTIAASLASDGLILGPILFFLAMNIILTAIKIGSGLYGYK
                     VGTSFIDKLSEQMAIVSRMANIVGVTVIAGLAATSVKISVPITFAAGKVDAANAAQKF
                     VTIQGMLDKIAPALLPALFTLLMYYLIKTKKWTTYKLVILTVIIGIVGSWLGVLA"
     gene            10883..11884
                     /locus_tag="TV188_001599"
     CDS             10883..11884
                     /locus_tag="TV188_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEL1534933.1"
                     /translation="MQRKVTINDIADLAKTSKTTVSFYLNGRFDKMSQETKSRIKEAI
                     EATNYKPSIAARSLNAKATKLIGVVIGDITNSFSNQIVKGIESKAQEFGYQIIIGNSN
                     YDPSREDELIEKMLNLGVDGFIIQPTSNFRKYSRIIEVKKKRMVFFDSQLYEHRTNWV
                     KTNNYDAVYDTIQQCITKGYQSFIMVTGNPNLLSTRIERASGFIDVLEANQLQYRQMI
                     IDENQTSSQEIAQFLQGAFDKERHNLVFVPNCWALPKVFTAMKALKVSLPETGLVGFD
                     NIEWTRLSSPSITTIIQPAYEEGEQATSILIDDIEGHSKEAKQQIFDCQVNWQESTF"
BASE COUNT         3477 a         2845 c         2448 g         3588 t
ORIGIN      
        1 gctcaggggg gattttaact tattactaat gtgcttgaat ggctatgata aggccttaaa
       61 agatagctgc ttaaagtcat ttcccacctt ttgatagagg tataagcctg atttttcaag
      121 actcaattga ccattaacca cctccttagc ctgattgtat ttgaccaccg ccaacaggcc
      181 ttgtttctta tcatggatca gctgaagctt actgtcattt cgaagcacct caatacgtgc
      241 ttcgctgcac accttgtcaa agtctgcttt gctgatattt ggaagtaggg tgtaggcata
      301 gctatcacta gcctgagaat gagtttgact gattgtgata aagctttggg agatgaggtc
      361 tttattgtta ctatttgtat taatctcaga ccaacagcct gactgcacct ttcgcgatag
      421 cgctaatgcg gttggcttgg caaaaaggta accaatatta gcttgaccgt ctttagaaag
      481 tagtaaaaga ctggtcacat catctcgata caggatctcc tctgttagcg ctgtctcctg
      541 cccattgata aaaagagtgt agctgttgtc tgggttttct ttgcgttgat caatggtagt
      601 agtcactgcc tgatgtgtct gactagtgat ggcggtgcca agaaaaacaa tttggtcatc
      661 taagatcgtc caagacttct tggcactcac tgtcctatcc caattttgaa aatccataac
      721 agctaaagct gttttgtctc ccgccttgat cgctccaaca aaggacgatg gcagggtaga
      781 catgcctgct ttttctttgg ccttttcttt ataatcattg gttagctttt ttaaataggc
      841 tactgtcacg tcctctcgcc tgacctctgc ttccgttgtt ccagccatct ttaaaggatt
      901 aacagtcggc caaaagtggt ctgagtaatg acccaaatca ctgttataaa ggtaaaacat
      961 gccatctcct gtataccaac cacgtgtatt ttcatcgttc atggcttcaa aattcagagt
     1021 tttgttggaa tgcatggata aagcaaaggc aaaatccttt tccgcattgt agtaggccaa
     1081 tttatccatc tggttaaaaa gagataggta gctcttaact ggactggctt ggattgtggt
     1141 atcctccaag agctctttga atagcttcat gtcatagtag cttgataggc tctctaaaat
     1201 agtctcctga ttatggaagg ccaaaacagc cttgatctta cccttgatcc tgattttagc
     1261 ttgctctggc aatgcctcag ccagtcttag cattcctctt agtgcttcta aggctgcctg
     1321 ccttgaggag gcattttcac gactgatgga gcgcccacga ctcatatcca tgagctcccc
     1381 atgaaccatc aagggcaaga aggcttgctc aatccaatga gtcatgacct ctagcttttg
     1441 ctggtctagg ctagtagcta atagctgaag taatggtacc agctgagaca agccatcaat
     1501 aaggacattg ccataggctc cagtgtaggc gacattggta tggtcaatat aagagccatc
     1561 ttcataaaag ccctcacccc ttgatccctt tggctgaaaa gcaaataagg tatctagggc
     1621 tgctatactg tcttgaagcg ctttcttatc atgctttaac agagcttcaa taatcttcac
     1681 tcgtcccata tcaacaaggt tacccccaat ggccttaaaa ggattcacaa gggttaagcg
     1741 aaattgtcta ggattaggaa caaagtgaga aattccttta gtatagcgct tgatctcctc
     1801 ttgagtgaca taagggtaaa tgaaggctag ggtattgaca atagctcttg gggtaccaat
     1861 ttcaaaatcc caccaattag ccttgccttc aatatccttt tgcggatgat agtaattaag
     1921 tgtcagccag gctaatttat ccttgatcag tcttatcagc tccttatcct gataatacct
     1981 agaggctagg ctactcacct gcttggccat ttcctctaaa cgcctacagg tagctgtcat
     2041 atgagacgat tgatgaagat ccgccaaatc actccaaagg tatgtgcttt tctgatcctt
     2101 ggtcagatca gctagattct tggtcacgct gtcgtccagt ttttggttta atgccaccat
     2161 ggctggactt gatcggtcaa agttttctgc tcccaaaatc acctcacacc actttgtgat
     2221 caaggaggtt gtttgagggg cttctgctgc taaaatctca actggtaccg ttgctactct
     2281 ttgcccctct tgatccaaca cctctaaaag cgttttcccc tgcgccaaag gaattaaaag
     2341 accattttcc acgcgcacaa tgttgctgga ctccgctgca atctgataat gatagtcagc
     2401 catttccatg aggtagtgct tatttaaagg caggacgatt tgctcctcta agtaatgtga
     2461 agcaatcttg atgtcatcac ttggcttatc accagcctct ctcaaagaaa ggttatcaaa
     2521 gaccacctgt ccatgaccgg cctcataaaa gagctctagc ttgatttgat taacctttag
     2581 cttagggata taaagctttt cttggtgttt tttctcagtt cctgttgcca tcgaagccac
     2641 aagcgttgct cttttgcagc accagaacct tgctttattt cttcaatgat acgcgcaaaa
     2701 gcctgacctg ttttatcctt tgtctcaatg tcaaaggtca gcaaatactg cttgtctgga
     2761 ttgatggcaa cggtttggtg cacacagcct ctaaatctct gattgccatc gctagtcatt
     2821 gtcagcttgt tatcagagac agcaatttta ggacagccct gactcttact agcgtcctta
     2881 taatccttcc aatcatttgc agactccttg ctccaaaggc ttgtactttg atgctcttga
     2941 gcaggactgg tctgatcaaa ttgaggattt ttaagcaggt tatcacctgt gagaatgagc
     3001 tgctccccaa gactggattc cgtagctact gacgacgcgt cttgagtgtc tggggagctt
     3061 tcttgagaag cctcctcagt ttttagtggt gctttcttta ccctctgaag ctccttggaa
     3121 atggcttttg ctgctgtttt ttcttctgct aagactgttg gtgcccgaaa taaacaagct
     3181 agtatgatac tagagcaaac agaagatgat agtttttttc tttgcttcat ctgatacctc
     3241 cttgcttttt taatgtttta tgaccgactt taacagctac tcatgtaatc tgcagccctt
     3301 gctgtgattg cctgaaattg accctgagct gccaattgat taaattctcc tccaactccc
     3361 agcacctgag cacctgcggc aaaccagtct gacacatttg tgacagttac gccacctgtt
     3421 accatgacat caacctgcgg caaaggagat ttgattgcct taataaagga catgccaact
     3481 gtggcacctg gaaagacctt gaccatctct gcacctgatt ccaaggcagt cacgacctcc
     3541 tcaatagtca tacagcccgg aatataagca atagcatatc gatgacatag gcggcttgtc
     3601 tgcctgctaa agctaggaga cacaataaat tgagcacccg ctaaaatagc tagccttgct
     3661 gtgacatcat caagaaccgt cccagccccg atcaggatct ctggatcatt gccaactgct
     3721 tcacgcaggc ctgcaataac ctgactggca aagggattag tataggccac ctcaatggtt
     3781 ttgatcccac cttcaatacc tgctaggctg caagccattg cttctttttt agaagctccc
     3841 cgaacgacta aggctaattt attggctttt agccttaaca tgatttctga ttttctcata
     3901 ttaccttctt acctctcggt ttcccttcat caccctatca acctgactaa caggaacaaa
     3961 gagctgatca tcagcaactg tacacttaag actagctgtc gcagcagcaa aatcaagcgc
     4021 agcagcaata gcctgtcctc tcatcaattg atataagcag cctgcaacaa aggcatcacc
     4081 actgccaact cgttgcaaaa caggcgttga tagctcaatg gagcgatgta actgcccatc
     4141 ataggcatag gctaggtaat gattgattcc ttggtcatcg atgtgacgtt ccgtgtgaaa
     4201 aatggctttt aagtgatatg cctcatataa ggcagccaag cgctccttga cagcaccttg
     4261 acctgcctta gctctatcaa acatggcatg atcagcttga ttacacatta agggctccat
     4321 accaaagatc aggtctgcat actgtgcaaa atgagagaac aatgtctttg cctccctgac
     4381 tgaaatcatc gagctgcgaa aattcaaatc aaaggaaaca cagacctgcc gcttcattgc
     4441 ctcaatagcc agctgctcaa caaggtcctg actgactttt cctaaagcca aggtaatgcc
     4501 actaaaatga aaatgagtaa cttcctcaaa tagtttacca taatccagat cttttgggcc
     4561 caataaacta aagctagagg cagagcgatc ataagcgacc tgactaggac ggcagccaaa
     4621 gccattttcc aaataataaa taccaacccg atcaccacac cattgcacat gctctgtggc
     4681 aacaccgctt tgcttcaaaa aggcctcaac gcttcgtcca acctgattat caggaagggc
     4741 agtcagcagg ctactctctg ctctaaagcc actaagcgtt cttgcaatat taacctctga
     4801 gccaccataa tacagctgtg cttgacaggc atgtcctaac gtctgaaaat gactgggact
     4861 gatgcgaatc agcggctctc ccaccaataa taccttggtc ataggggtat cctttctata
     4921 gctgcagata agacttattg ctgaaggact tctcttaggt agtcgacaag gtctgatggc
     4981 tcggcattag caaagaaata atgctggaag tgctctccag aaatggtttc cttcaagaaa
     5041 tcttgatcaa tctcctttaa cacctccaac aaagaacgat aagtcacagc cttcaattcg
     5101 ctcaaaattc tagcgttacg ttgctctggg atggcccgct ctttgggata gccgcccccc
     5161 atcggctcag caaataagcg ctcaaacatc agggtcaggt taagctctgc cccccaacca
     5221 aagccctttg caaatggaat agacaaggca ttgccaccat taatctgagc aaaaaggtag
     5281 gcttctgttg gctcactagc aaagccacag gtcacacctg gaaagctatt taaggccagc
     5341 atagcaccca caccagtccc acagcccgtt acaacaaaat cagctgcctt acttgtcaat
     5401 aaaatagaag ctagtagccc gttttgcaca taggtcagct gactttcgcc ctccttgcca
     5461 tacataccat agttaaagac ctcatagcca tgcttattag taacagagac taaggtctcg
     5521 taaataatac tgtttttagc tgcttgactg ttttcattaa ttaatgcaat tttcatcttc
     5581 tgtaatctcc tttgatgctt ttttgtttct ttacggttgt ttgccaatgt aagctaaaat
     5641 gcctccatca acataaagga tatgcccatt gacaaagtta ctcgcctcac tagccaaaaa
     5701 tatagctgga ccagccagat ctgctggtgt tccccaacgc gctgccggag tcttagcaat
     5761 aataaactga tcaaaggggt gacggctgcc atcagcctga cgctctctta aaggtgctgt
     5821 ctgaggcgtt gcaatatagc caggcccaat gccattgcac tggatattgg cttctccaaa
     5881 ttctgaagcg atgtttttgg ttaacatctt aagaccaccc ttagctgccg cataagcact
     5941 aaccgtttca cgaccaagct cactcatcat cgaacagata ttgatgattt tcccatgccc
     6001 ttttttaatc attgatggca gaactgcctt tgaaacaata aatggcgcat tcaggtctat
     6061 atctaccacc tgacgaaaat ccttagccgt catctcaagc atcggtgtcc gtttaatgat
     6121 acctgcatta ttcacaagaa tatcaataat accaacctct ttttcaatct gagccaccat
     6181 ctcttgaatc cctacttcat cagtgacatc acaaacatag ccatgagctt taatgccaaa
     6241 ctctcgataa gctgctaatc cttgatccac taaatcctgc ttgatgtcat taaagacgat
     6301 ctttgctcca gccatggcat aggccttagc aatctcaaag ccaatcccat acgaggctcc
     6361 cgttatcaag gcaattttgc cctctaaaga aaagaaatgt tccattgttt tacctctcaa
     6421 tctcaatatt taagtaaacc tgtttatcaa aactatagca agactaatcc attttgtcaa
     6481 tcattttagt aaaaacacaa aaaagagcta aagtttttct tattgtcatt atcgaggaag
     6541 gcttcttagc tatatttttc ttgctcttac tcgctttact tcctataagg atcccaaaaa
     6601 ttaggccata ttgatcgctt attttgataa aataacaaaa aagtgttgac aaacattttt
     6661 gaaagcgcta taatttttct gagtaaaccg gtaaactaaa aaggagctta ttcatgattt
     6721 ctattattgt tattggtcat gggcattttg ccagtggtat tgtctcgtct ttagagttaa
     6781 ttgcaggcaa gcaagagggc ataactgcta ttgattttac tgctgagatg accgctgctg
     6841 atgtgcatga gcgcctatca gtagtcttac agtcaaagac tcaggcactt atgctttgtg
     6901 acttattagg cggcacccca tttaaggtag cagctacctt gatggaggag ctttctgaga
     6961 gcacacttga tgtcctgtct ggactcaatc tagccatgct aatagaagca gtctttgcta
     7021 ggcaagagca gcttgatcta gaacaaattg tcgctaagct attaaccaca gccaaggaag
     7081 ggatcagtaa ttggaaatcc ctctctggtg aggctgatga agcagacctt gatgaaggag
     7141 ggatttaatg actagacaga tcaaagaggt tacccttgag cctctcatac aagcagaggt
     7201 ctatagccag cagccatatc taacaaaagc tgatattgag gcagctattt tattagccct
     7261 taagcaaatc cgattaaaca tggattattt tggtactgat ttccctaggc cagccactaa
     7321 ggacaattgc tacccaatta tggataatac cgagtggacc aatggctttt ggaccggctg
     7381 cctatggctg gcctacgaat acactggtaa tgacactatc aagtcactag cacaggcaaa
     7441 tgacctgtcc ttcttagaac gcgtcaccaa agacattgag cttgaccatc atgatttagg
     7501 atttctttat tcaccctctt gcatggctga gtggaagctt ttaaaaacac ctgaagccag
     7561 acaggcagcc ttaaaggcag cagataaatt gattgagcgc tatcaggaaa aaggcggctt
     7621 tattcaagcc tggggacaac tcgggaaagc agaagattac cgcttaatta ttgattgtct
     7681 tttaaatatc cagctactct tttttgccag tcaagaaaca ggagatgaca ggtatcgtca
     7741 aatggctatc aatcactttt atgcctcagc caacaatgtg attcgtgatg acgcctctgc
     7801 ttatcatacc ttctactttg accctgaaac aggtgatcca atcaaaggag ttacacgcca
     7861 aggctacagt gatgactccg cctgggccag aggacaagct tggggaatct atggaattcc
     7921 cttgacctat cgcttcttga aggatccaca gctaattgcc ttatttaaag gaatgacgca
     7981 ctatttcctc aatcgcttgc ccaaggatca ggtatcctat tgggatttga tctttgaaga
     8041 tggcagtggt cagtctaagg acagctccgc aactgctatt gctgtttgtg gtattcacga
     8101 gatgttaaaa catttaccag agaatgatcc tgacaagaaa gcttatcaag ctgccatgca
     8161 ctgtatgctc agatcattaa ttgatagcta tgccaacaag gacatcaagc ctggtgctcc
     8221 acttttacgt catggcgttt actcttggca ctctggcaag ggcgttgatg agggaaatat
     8281 ctggggagat tactactatt tagaagccct gctgcgcttt tacaaggact ggacccctta
     8341 ttggtaggct gatagcattt agcctacaaa gactattgtt aaaggagata ttatgacacc
     8401 accaaacatt atcatgacca gagttgatga gcgtttgatt catggtcaag gccagctatg
     8461 gatcaaattt ttaaattgca acactgtcat tgtggctaat gatgccgttg ctgaagacaa
     8521 aatccaacag tctctgatga aacctgtcgt tccatcaagc attgccatgc gctttttttc
     8581 cattcaaaag gtgattgacg tgattcacaa agcaagccct gctcagacaa tctttattgt
     8641 tgttaaggat ttagaagaca tcaagcgctt ggttgaagga ggggtgccca ttaaagaggt
     8701 caatcttgga aacattcata aaacagacga taaaatcgcc attacccaat tcatttcgct
     8761 aggcgacaag gacaaggcta ttattcggac attgactcac gatcatcata ttgtctttaa
     8821 cactaaaaca actccagctg gcaatggtgc ctctgaggtt aatattttag attatattta
     8881 agaaaggaaa ttgatatgga tatcaatttg ttacaagcac ttttaatcgg tctttggaca
     8941 gccttttgtt tcagcggaat gttacttggt atctacacca atcgctgtat cattctgtct
     9001 tttggtgtcg gcattatctt gggggacttg ccaacagcac ttagcatggg agctatatct
     9061 gaattagctt atatgggatt tggtgtcggt gctggtggta ctgtgccacc caacccaatc
     9121 ggacctggta tctttggtac cttgatggct attaccagtg ctggtaaagt tactccggaa
     9181 gctgccttag ctctttcgac accaattgcc gttgctattc aatttcttca aacctttacc
     9241 tatacagctt ttgctggtgc tcctgaaaca gctaaaaaac agcttcaaaa agggaatatt
     9301 aaaggcttta catttgccgc caatggtacc atctgggctt ttgctgtgat tggcttagga
     9361 cttggtttat taggcgcctt gtcaatggat actttacttc atttggttga ttatatccca
     9421 cctgtcctcc taaatggatt aaccgttgct ggtaaaatgc ttcctgctat cggttttgct
     9481 atgattctat ctgttatggc taaaaaagag ctgattcctt ttgtcttaat tggttatgtc
     9541 tgtgcagctt acctgcaaat tccaaccatc ggtattgcca tcataggcat tatcttcgcc
     9601 ctaaatgaat actacaacaa accaaagcat gcaacaacag ctgaacaagg aggtcaacaa
     9661 gatgactgga tctaataagc tcacaaagcg tgattatctg aaaactgctc ttagagcctt
     9721 tttcctgcaa aatggcttta actatagcaa ttatcaagga ataggctatg ccaatgtcgt
     9781 ttacccagcc ctaaaaaagc attttggcaa tgacaaaaca ggcctttaca aagcactaga
     9841 gaacaattgt gcattttaca atacaaaccc tcatttccta ccttttatca ccagcctaca
     9901 cctggtcatg ctagaaaata atcggcctga agaagaaacc cgcaatatca agatggcact
     9961 catgggacct ctagcaggca tcggggatac ccttacgcaa ttttgtttag caccactctt
    10021 ttcgaccatt gctgcttcct tagcaagtga cggcctgatt ttggggccaa ttctcttttt
    10081 cctagccatg aatattattc taacagctat taaaattggc tctggactct atggctacaa
    10141 ggtggggaca agctttattg ataaattaag cgaacaaatg gcaattgtat ctcgcatggc
    10201 aaatattgtc ggagttacag tgattgctgg tctagctgct acttctgtta agatatctgt
    10261 tcccatcaca tttgcagcag gcaaggtcga cgctgcaaat gcagcccaaa aatttgtgac
    10321 cattcaggga atgctggata agattgcacc agctcttctg ccagccctct tcactctctt
    10381 gatgtattac ctcattaaaa cgaaaaaatg gacaacctat aaattagtta ttctaacagt
    10441 tattattggt attgttggca gctggttagg ggtgttagcc tagcagtctt agagattctg
    10501 ttaatcagta ttggagggtc tccattagcg atgagcaggt ctcttttcta ttgggcaaag
    10561 ctaagcattg acaccatcaa ctctcgtagc ctcagtcagg tcttttgccc tgtagagcct
    10621 ttaagcacaa gcctttactg ctagctgtga tgaaggcgtc ctccttctac tggcttctgg
    10681 cacaattaat cctttatatc tctacaagca catgatttag cggctgattg cgcgccaatc
    10741 ttacagaagg tcgcaactta agaaagagta ggatcatttt tgacctcttc aaaggtcata
    10801 ttcttggact gaaatattaa aacaattacc attccatatg ttataataaa actactaatg
    10861 atgacaaaaa ggggtctatg caatgcagcg caaagtaacc atcaatgata ttgctgactt
    10921 agctaaaact tcaaaaacaa ctgtttcttt ctacctcaac ggtcgatttg ataaaatgtc
    10981 tcaggagaca aaaagccgga tcaaggaggc tattgaagcc accaactaca agcctagcat
    11041 tgcagctcgc agtctcaatg ccaaggctac caaattgatc ggtgtggtta tcggtgacat
    11101 caccaatagc ttttccaacc agattgtcaa aggtattgaa agcaaggcgc aagaatttgg
    11161 ttatcagatt atcatcggca acagcaacta tgatccttca cgtgaggacg aattgattga
    11221 aaaaatgctt aacctaggtg tagatggttt tatcattcaa ccaacctcta actttagaaa
    11281 gtattcacgc atcatcgaag tgaaaaaaaa gcgcatggtt ttctttgaca gtcagctcta
    11341 tgagcatcgt acaaactggg tcaagaccaa caattatgac gctgtttatg acaccattca
    11401 gcaatgcatc accaaaggct atcaaagctt tatcatggtt actggcaatc ctaatttgct
    11461 gagcacacgc atcgagcgtg cctctggttt tattgatgtt ttagaggcta accagctcca
    11521 gtatcgtcaa atgatcatcg atgaaaacca aaccagctct caagaaattg ctcagtttct
    11581 acaaggcgca tttgataagg aacgtcacaa tctggtattt gtcccaaact gctgggctct
    11641 gcctaaggtt tttactgcca tgaaggcact aaaggtatca ttgcccgaaa ctggtctagt
    11701 tggctttgat aacatcgaat ggactcgctt gtcatcacca agtattacca ctattatcca
    11761 gcctgcttac gaagaagggg agcaagcaac cagcattttg attgatgata tcgaagggca
    11821 tagcaaggaa gccaagcaac aaatttttga ttgtcaggtt aattggcaag aatcaacctt
    11881 ctaacaggat tttttcgcct tctagacctt aaaaaatcag ccattctaat aacgatgaca
    11941 aagtaacacg aggcttaacg cttgtttgct agcatcagaa aaaacacata aatcagcctg
    12001 aactacccgg ttgatgaaac aataaaccat taagcaacgg tcttattcct cataccaaga
    12061 ggagcaaggc cgttttgacg tttttgacaa tggtcgttat tgtaaacgta acggtagtgt
    12121 attactgaca ggctcttcaa aaaagctgtc gtccttaggt catacgaggc cttcttttac
    12181 aagcgactgc tacttcttca ctactagtgt gatcttttag ccaatttctg agaacatcat
    12241 cagtaaaatc tcgcacctgc caataatggc aagcaagctt ttttgaccag caagttaatc
    12301 atgtatcact tgtgacttca actcttaact gtttgtcctt tcaagtctac tataagag
//
LOCUS       DARYYD010000056        12157 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.057, whole genome shotgun sequence.
ACCESSION   DARYYD010000056 DARYYD010000000
VERSION     DARYYD010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12157
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.057"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(152..433)
                     /locus_tag="TV188_001600"
     CDS             complement(152..433)
                     /locus_tag="TV188_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEL1534934.1"
                     /translation="MTTQKAYMYVLECADKTLYTGYTTDLDKRLKAHNAGKGAKYTRC
                     RLPVSLLYYESFDSKQAAMRAEALFKKRNTRQQKLTYIAEQQNKKAKPD"
     gene            complement(466..1233)
                     /locus_tag="TV188_001601"
     CDS             complement(466..1233)
                     /locus_tag="TV188_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEL1534935.1"
                     /translation="MLHSILKDGERIDQLFSSDVQIIQNKEVFSYSIDSVLLSRFPKL
                     PSRGLIVDLCSGNGAVGLFDSTQTKASIVEIELQPRLADMGQRSIRLNQLEDQVTMIC
                     DDLTNLLQHVPRSGVDIILYNPPYFKSSQTSKKNLSEHYLLARHEITTNLAKICQIAR
                     HALKSNGRLAMVHRPDRFLEILDTLKINGLAPKRLQFVYPKLGKEANMLLIEAIKDGS
                     MEGLKILPPLIVHKDNGDYTDTIKEIYFGAKDKAFKN"
     gene            1352..2092
                     /locus_tag="TV188_001602"
     CDS             1352..2092
                     /locus_tag="TV188_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEL1534936.1"
                     /translation="MFYVYLRGLVVFLLWVVNGNAHYHNEDRILDKSENYILVAPHRT
                     FWDPVYMAFAARPKQFIFMAKKELFTNRLFAWWIKMCGAFPIDREKPSPDAIRYPVNM
                     LKKSNRSLVMFPSGSRHATDVKGGVAVIAKMAKVKIMPAAYQGPMTLKGLLAGERVDM
                     NFGHAIDVSDIKRMNDEEIEEVARRIQAEFDRLDQEMAPFKSNQRRSMLTYLYRIPLG
                     ILLVLILALTMLFSYLASFVWDPDKHRS"
     gene            2411..3091
                     /locus_tag="TV188_001603"
                     /pseudo
     CDS             2411..3091
                     /locus_tag="TV188_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184716.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
     gene            3072..5315
                     /locus_tag="TV188_001604"
     CDS             3072..5315
                     /locus_tag="TV188_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEL1534937.1"
                     /translation="MRFPLTKYFPIAPIQFALLVLVLHYLIYRPSWLTAGLLAGLLVL
                     LGYRFVLKQVLKTLLLLGLFGCLFAYQKGQLEANQINQPDRLSTVELIPDSIMVNGDH
                     LSFIGRHSGHHYQLAYRMTSKEEADFFKQQSQFLKLKADIRLEEAAGLRNFKGFNHQA
                     YLAYQGIFRVGKIKSLQSLKTISPRSVSDRISQWRRQAIVWCQSRFPQPMSHYMTGLL
                     FGYLDKSFGQMTELYSQLGIIHLFALSGMQVGFFLTYLRRGLVWLHIPIDKIKLLEVV
                     CSFCYSGLTGHSISVIRSLLQAQLRHIGLTGLDNLAMTFLMMFLINGHFLMSIGGVLS
                     FAYAFIIATVRFEELSGNKQRLLKALAISFGIVPLLAYYFSVFNPISVVLTALLAYLF
                     DGLILPGLAILFFFSPLAVVTAVNPFFLYLEKGIGMIGSYFSAPLVLGSPTALQLCLC
                     MACLAIVYDYRGNRGLQLVAGGLLLLTLFTVKWPMTNEVTLVDVGQGDSIFIRDKQNH
                     TMLIDVGGVPAPQEKEQWRRKYQACNAHKTLIPYLRSRGVDTIDQLVLTHTDTDHVGD
                     MEAVVKAFRVKQIYVSQGSLTNASFVKRLQGLAAKVKAISAGDHLPIMGSFLEVLYPW
                     EIGDGKNNDSLVLYGRLLDKSFLFTGDLEAEGEERLIARYPKLKADVLKAAHHGSKGS
                     SIPAFLDHIQPQLSLISAGRNNQYQHPNPETLARFEARHIPYYSTASKGAIRLTGQAH
                     WQLESCR"
     gene            5428..6489
                     /locus_tag="TV188_001605"
     CDS             5428..6489
                     /locus_tag="TV188_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEL1534938.1"
                     /translation="MIAIEKIDALSKESLGLITVVTGEDIGQYSHMKALLLKKIAFDP
                     ADLTYSYFDMSEALYQTAEMDLVSMPFFADQKVVIFDHLLDITTSKKSYLKEKELKAF
                     EDYLENPVETTRLVIFAPGKLDGKRRLVKILKRDALIFEASPLKAAEKRTYFQKYSHQ
                     LDLSFASGAFDQLLLKSNDDFSQIMKNMTFLKAYKKSGPITVEDIAQAIPKSLQDNVF
                     DLTRLVLQGKIDAARELVHDLRLSGEDDIKLIAIMLGQFRLFLQLATLVRSGKTEQQL
                     VTSLSDLLGRRVNPYQVKYALKDSRALSLSYLQLAVKTLIETDYHIKTGVYTKDYLFD
                     LALLKLVAHSQGNTDLSDL"
     gene            6567..7172
                     /locus_tag="TV188_001606"
     CDS             6567..7172
                     /locus_tag="TV188_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEL1534939.1"
                     /translation="MTITLPDLPYAYDALEPYFDTETMTLHHDKHHATYVANTNTALE
                     KYPELGENLEELLADVSSIPADIRQAVINNGGGHLNHALFWELLSPEKQEVSADVAAA
                     IDDAFGSFAAFKEQFTAAATGRFGSGWAWLVVNKAGQLEITSTANQDTPISEGKQPIL
                     ALDVWEHAYYLNYRNVRPNYIKAFFEIINWKKVSEFYQAAK"
     gene            complement(7423..8637)
                     /locus_tag="TV188_001607"
     CDS             complement(7423..8637)
                     /locus_tag="TV188_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1534940.1"
                     /translation="MKYIHSGLMFLLFVLFVVSFAKHEQARLAFEQSHQAYKDMVISF
                     EKRHIKQQPSSLSDQFQLRKDLLHYAKKLAQDGWSYEAIEKGYLGHLKPKQASYNFEQ
                     LYQSLQIIGSPAFHRMWERQPRAQHKLEAKRDLSLLLSYVKMPEELSGQSAETKQLLK
                     QFSPSLSPTDAFWDQLASLIQLYYDHLEHIPYQTFNRKLYQLRYVLSVQQIEWVRNNY
                     GRAGKTDADALARYLATLDESDYSLNESARYHNKVASHLDTANQLQITYPDNFPQANY
                     KILIHFHSEFILSEAGHFLAALDPQQPSQNGLINGSSFNYANQNNDLHRLLDIEPIEL
                     FEPDFIETAMINLDSPFIVPDLEQQNDQQHPIFSRDGKSSKQLTKAAAKAFKKLLRHY
                     QQAHQSFPSKTP"
     gene            complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TV188_001608"
     CDS             complement(8647..9675)
                     /gene="queA"
                     /locus_tag="TV188_001608"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEL1534941.1"
                     /translation="MNTNDFDFELPEELIAQTPLEQRDRSKLLIIDHQEHTMTDSHFD
                     HIIDQLEPGDALVMNNTRVLPARLYGEKMETHGHVELLLLKNIQGDQWEVLAKPAKRL
                     KAGAQISFGDGRLKARVIQELEHGGRIVEFSYDGIFLEILETLGEMPLPPYIHEKLAD
                     AERYQTVYAKENGSAAAPTAGLHFTQELLQKIEAKGVHLVYLTLHVGLGTFRPVSVDN
                     IDEHDMHSEFYLLSEEAAQTLRKVKAAGGRIIAVGTTSIRTLETIGSKFQGQILADSG
                     WTNIFIKPGYQFKVVDAFSTNFHLPKSTLVMLVSAFAGRDFVLEAYKHAIDEHYRFFS
                     FGDAMFVK"
     gene            9943..10647
                     /gene="nagB"
                     /locus_tag="TV188_001609"
     CDS             9943..10647
                     /gene="nagB"
                     /locus_tag="TV188_001609"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEL1534942.1"
                     /translation="MKIIRVQDQLEGGKVAFSLLKESLAKGATTLGLATGSTPITFYQ
                     ELVNSDLDCSALTSINLDEYVGLPVENDQSYDYFMRDQLFNAKPFKESFLPNGLADDL
                     EAEVKRYDQVIAEHPIDFQILGIGRNGHIGFNEPGTSFAEKTHVVDLQASTIEANSRF
                     FASIDDVPKQAISMGIASIMASKMIVLLAFGKEKAAAIKGMVSGPVTEALPASVLQQH
                     GNVVVIIDEAAASELD"
     gene            10819..11535
                     /locus_tag="TV188_001610"
     CDS             10819..11535
                     /locus_tag="TV188_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEL1534943.1"
                     /translation="MRLDKLLEVTGFGSRNQVKQLIKGRSVLIDGQPARAGCQSVDSG
                     LQVIMVNGRQIKAFAHRYYLLHKPAGVVSACSDRKHQTVIDLIRKEDRVANLYPIGRL
                     DRDTTGLVLLTDNGPLGFRMLHPKHHVNKTYLVTVNGSLAADAVPFFENGVTFLDGTR
                     CKSAALRIIKADQMESQAEVTLSEGKYHQIKKMFLSYGLKVTQLKRIGFAEIALGDLA
                     EGAYRQLTVKEKKLIKTYLT"
     gene            11627..>12157
                     /locus_tag="TV188_001611"
     CDS             11627..>12157
                     /locus_tag="TV188_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEL1534944.1"
                     /translation="MLTALDQDQRVISLTDGSSPSRKQAFTCPACGAAVRLKKGRIIR
                     PHFAHISLSHCQYLTENESHEHLRLKADLYRSLSRSETAEVEAYLPDLNQIADLLVNK
                     HLALEIQCSQLPIKRLEQRSRAYQANGYQVRWLLGRKLWLQKRLTGLQRQCLYFSWQL
                     GFHLWELDVEHHLIRLK"
BASE COUNT         3303 a         2348 c         2832 g         3674 t
ORIGIN      
        1 aagtccttgg aggttttgtt ttgctgcttt tttggtcttg gtctttagta gccttgggca
       61 agcggagctt tgacctagtg tgggtctgtc tcaactgttg tcagctagtc ccatagtggt
      121 gcttggccgc ggcttaggag gcgtcaggag cttagtctgg cttcgctttt ttattttgct
      181 gctctgcaat ataggtgagc ttttgctgtc tggtgtttcg ttttttaaac aaggcttcgg
      241 ctctcatcgc agcctgcttg ctatcaaagc tttcataata cagcaggctg acaggtaagc
      301 gacagcgtgt gtattttgct cctttaccag cattatgggc tttgagacgc ttgtctaaat
      361 ctgttgtata gccagtatag agggttttgt ctgcacattc taaaacgtac atgtaagcct
      421 tttgagttgt catgatgaaa aaacctcttg atgcagaaga gcctgctagt tcttaaaagc
      481 cttgtccttg gctccgaaat aaatctcctt aattgtatcg gtatagtctc cgttgtcttt
      541 atggacaata agtggtggca ggattttcaa gccttccata gaaccatcct tgatggcctc
      601 aatcaagagc atgttagcct ccttaccaag ctttgggtag acaaattgca gccgctttgg
      661 agcaagaccg tttattttta aggtatcaag aatctctaaa aagcgatcag gtcgatggac
      721 catagctaga cgaccattgg acttgagcgc atggcgtgct atctgacaga tcttagccag
      781 atttgttgtg atttcgtgtc tggctaggag ataatgctca gataggtttt tctttgaggt
      841 ctgactgctt ttaaagtaag gaggattata aagaatgatg tcaacacctg agcgaggcac
      901 atgctgaagc aggttagtca aatcatcaca aatcatcgtc acctgatcct ccaactgatt
      961 gagcctgata gagcgctgtc ccatatcggc taagcgtggc tgaagctcaa tttcaacaat
     1021 agaggccttg gtttgtgtac tgtcaaataa gcccactgcc ccatttcctg aacacaaatc
     1081 tacaatgagc ccacgtgatg gaagctttgg aaagcgagaa agcaagacac tatcaataga
     1141 gtagctaaag acctctttgt tttgaataat ctgaacgtcg cttgagaaaa gctggtcaat
     1201 ccgttcacca tcttttaata tcgaatgtag catatcatta ttatagcaaa aataatccta
     1261 tcagagtagg gggtgctgat tgagctttcc ctttaatatt aaaatatttc atggtacaat
     1321 gagtaggatt ataagtgaaa aggagactga tgtgttttac gtctatttac gtggcttagt
     1381 tgtcttttta ttgtgggttg ttaatggtaa tgcccactac cataatgagg ataggattct
     1441 tgataagtct gaaaattata ttctagttgc tccgcatagg accttttggg atcctgttta
     1501 catggcattt gccgcacgtc caaagcagtt tattttcatg gccaaaaaag agctcttcac
     1561 caatcgttta tttgcctggt ggattaagat gtgtggagcc tttccgattg atcgcgaaaa
     1621 gcctagtcca gatgccatta gatatcctgt taatatgctg aaaaaaagca atcgctcttt
     1681 ggtgatgttc ccaagtggga gccgtcatgc gacagatgtc aaggggggcg ttgctgttat
     1741 tgccaagatg gccaaggtca aaatcatgcc agcagcctat cagggtccta tgaccttaaa
     1801 gggcttatta gcaggtgagc gtgttgatat gaactttggt catgcgattg atgtttccga
     1861 cattaagcgt atgaatgatg aggagattga ggaggtagct aggcgtattc aggctgaatt
     1921 tgaccgctta gaccaagaaa tggctccctt taagtctaat caaaggcgct ctatgctgac
     1981 ctatctttac cgtattccat taggaatact tctggtgctt attttggctt taaccatgct
     2041 attttcttat ttagcaagct ttgtttggga tccagacaag caccgctctt aggtcgtgtt
     2101 atggattagc gctgaaggcg cgcaaaaatc agggctttgt tgctactcta ctgagactgg
     2161 cttgcagtta cccttctgac atgttatgtc taggatacga atgctactgg ttactcaagg
     2221 ctacaagaaa gccagcactt tccacagtaa ggggattagg taagccaagg taggttatgc
     2281 ttgtagtgta gctgtatgtt acaatttgat gaggttgaag aggtagtcca ttttggactg
     2341 ctttttttaa tatgctagaa aataggacaa ttttaaaggc ttttatcgaa taatatattg
     2401 aggtgaaaac atgttagaag aattgttctt aaagagtaaa gagatgataa agtcccctta
     2461 ttttctgtca cgttgtgtta ctggtgtgct gtctgtaggg cttttgctgg tgctgtggat
     2521 tgccttgact ggcaaggaaa aagcaagaga ggagtcagct ccatttcctg accattctca
     2581 ggttcagcag tcagaaaagc cagctcagct agaagctagt gagcaagaaa tggcggcagc
     2641 tgaggatatc gtagtggata ttaagggagc tgttcataag gagggtgtct ataagcttgc
     2701 taagggaagt cgtatcacag atctgattga gctagcaggt ggcttgacag accaagctga
     2761 taaaaatgct attaatctag ctgaaaagct atctgatgaa aaggtcgttt atgttgctaa
     2821 gctgggtgag aatatatcag tcattaaagg atcttcagct gaggctcaat cagcgtctgc
     2881 tgatcatcag aagcctgaaa aggttcattt gaacagagct agtcttgctg atttgcaaag
     2941 cattccaggc attggtgcaa agagagcata ggatattatt gatgtacgag aaagcctggg
     3001 tggctttaaa tctctagaag atctgagaaa ggtatcaggt attggtgcta aaacactgga
     3061 gaagctaaag catgagattt cccttgacta agtattttcc aattgctccg atacaatttg
     3121 cccttttagt gcttgttttg cattatttga tttatcgacc tagctggtta acggctggtt
     3181 tgttagctgg cttgttggta ttattaggct atcgctttgt cctcaagcag gtcttaaaga
     3241 cgcttctttt gctagggctt tttggctgtc tttttgctta tcaaaagggt cagctagagg
     3301 ctaatcagat caatcagcct gatcgcttat caacggttga gctgattcca gattcgataa
     3361 tggtgaatgg tgatcaccta tcctttatcg gtcggcactc ggggcatcat tatcagttgg
     3421 cttatcgcat gacctcaaaa gaagaggcag atttttttaa gcagcagagc caatttctaa
     3481 agctaaaggc tgacatcagg ctagaggaag cagcagggct tagaaatttt aagggcttta
     3541 accatcaggc ctatttagct tatcagggaa tctttagagt aggaaaaatc aaaagcttgc
     3601 agtcattgaa gactatctct cctaggtctg ttagtgatcg tattagccaa tggcgacgtc
     3661 aggccatcgt ttggtgccaa tctaggtttc cacagccgat gagtcattat atgacaggat
     3721 tgttatttgg ctatcttgat aagtcctttg ggcaaatgac agagctatac agccagctcg
     3781 gtattatcca tctgtttgct ttatctggta tgcaggtcgg cttttttctg acctacctgc
     3841 gtcgtggctt ggtctggtta catattccaa tagacaagat taagctactg gaggtggtat
     3901 gttcattttg ctattctggt ttgactggtc atagtatttc tgtgatacgt agcttgctgc
     3961 aggcccagct gcgtcatatt ggtttgacag gactagataa tctagcaatg acttttttga
     4021 tgatgttttt gattaatggt cactttctga tgtctattgg tggtgtcttg tcctttgctt
     4081 atgcttttat cattgctacg gtcagatttg aagagctttc tggcaacaaa cagaggcttt
     4141 tgaaagcctt agccatttcc tttggcattg tgcccttgct ggcctactat ttctcggttt
     4201 ttaatccgat ctcggtagta ttgacagcct tattagccta tttgtttgat ggtcttattc
     4261 taccaggtct agcgatcttg tttttcttct cgccccttgc tgttgtgact gccgtcaatc
     4321 cattcttttt atatttagaa aaggggatcg gcatgattgg aagctatttt agtgctccct
     4381 tggtgttagg aagtcctaca gccttacagc tttgcctttg tatggcttgc ttggctatag
     4441 tgtatgatta tcgagggaat cgaggcttac agttggttgc aggtggtttg ttgttgctga
     4501 cgctatttac ggtaaaatgg cccatgacta atgaggtaac gcttgtagat gttgggcaag
     4561 gagacagtat ttttattagg gataagcaaa atcataccat gctgattgat gtcggaggag
     4621 tgcctgctcc tcaggaaaag gagcaatggc ggaggaaata ccaagcctgt aatgcccaca
     4681 aaacactcat tccctatctt agaagccgag gagtagatac gattgatcaa ttggtgctaa
     4741 cccacaccga tactgatcat gtgggggata tggaggctgt tgtgaaggcc tttagagtta
     4801 agcaaatata tgttagtcag gggagtttaa ccaatgctag ctttgtcaag cgattacaag
     4861 gattagctgc caaggttaag gccattagtg ctggtgatca cttgcccatt atgggaagct
     4921 ttttagaggt gctctatcct tgggagatag gagatggtaa aaacaatgat tctttagtcc
     4981 tttatggcag gctattggat aaaagctttt tatttacagg tgatttggag gcagaaggag
     5041 aagaaaggct gattgctcgt tatcctaagc ttaaggctga tgttttaaag gcagctcatc
     5101 atggttctaa gggctcttct ataccagcat ttttagacca tatccagcct cagctaagct
     5161 tgatttcagc aggaaggaac aaccagtatc agcaccctaa ccccgaaacc ttggcacgct
     5221 ttgaagcgag acacattcct tactacagca ccgcaagcaa gggcgctatt cgcttaacag
     5281 gtcaagctca ctggcaatta gaatcctgta gataggctca ttgaaccaga gatatatgca
     5341 agggcctagg tctgggaatg aagtagagaa tgaaaaagat cagctttagc aaggtcatat
     5401 ttagtaagaa aatgctataa taaaaccatg attgcgatag aaaaaataga tgccttaagc
     5461 aaagaaagct taggcttgat tacggtcgta actggtgagg atattgggca atatagccat
     5521 atgaaggcgc tgctactaaa aaaaatagcc tttgatccgg ctgacttgac ttattcttat
     5581 tttgatatgt ctgaggcttt gtatcaaaca gctgagatgg accttgtaag catgcccttt
     5641 tttgctgacc aaaaggtggt tatttttgat catctgctgg acattaccac tagtaaaaaa
     5701 agctacctaa aggaaaaaga gctaaaggca tttgaggact atttggaaaa tcctgtagag
     5761 accacacgtt tggttatctt tgcaccagga aagcttgatg gcaagcgtcg tttggtcaag
     5821 attctcaagc gtgatgccct tatttttgaa gccagtcctt taaaggctgc tgaaaaaagg
     5881 acctattttc aaaaatacag tcaccagctg gacttgagct ttgctagtgg tgcttttgat
     5941 caattgctgt tgaagtcaaa tgatgatttt agtcaaatca tgaagaatat gaccttcttg
     6001 aaggcctata aaaaaagtgg tcctatcaca gtagaggaca ttgctcaagc gattcccaag
     6061 agcttgcagg ataatgtctt tgacttgaca agattggtgt tacaaggaaa gattgatgct
     6121 gctcgggagc tggttcatga tttgcgccta tctggcgagg acgatattaa gcttattgcc
     6181 attatgctgg ggcagtttcg tctgtttttg cagctggcaa ccttggtgcg gtctggaaaa
     6241 acagaacagc agctagtcac tagcctatca gacctgttag gcagacgtgt taatccctat
     6301 caggtgaaat atgcactcaa ggattctaga gccttgtctc tctcttattt gcagctggct
     6361 gtaaagacct taattgaaac agattatcac attaaaacag gtgtttacac aaaggattat
     6421 ctttttgacc ttgctctctt aaagctagta gcgcattctc agggaaatac tgacctctca
     6481 gacctatgag catcaatcaa attagttgaa agcctctatt ttttgagata agatagactt
     6541 atcataaagg aaaagaggaa agagacatga ccattacatt accggatctt ccgtacgcat
     6601 atgatgccct tgagccttat tttgacacag aaacaatgac gcttcatcat gataagcacc
     6661 atgccaccta tgtggctaat accaacactg ctttggaaaa atacccagag ctaggagaaa
     6721 atttagagga attattagca gatgtaagca gcattcctgc tgacattcgt caggctgtga
     6781 ttaataatgg cggtggccat ttgaaccatg cgcttttctg ggagctgctt tctccagaaa
     6841 agcaagaggt ttctgctgat gtcgcagcag ctattgatga cgcttttggt tcctttgctg
     6901 cctttaaaga gcaattcaca gcagcagcta cgggtcgttt tggctcaggt tgggcctggc
     6961 tggttgtgaa taaggctggt cagcttgaaa tcacatcaac tgctaatcag gacacaccaa
     7021 tctcagaggg caagcagcct attttagcac ttgatgtttg ggagcatgct tattacctca
     7081 attaccgcaa tgttcgtcca aattatatca aggccttctt tgaaatcatt aattggaaaa
     7141 aggtctcaga gttttaccaa gctgcaaaat aatagaagtc agttaccaat ctcagaagta
     7201 gattggtttt ttaagtgtgc taataaacta ctagtgttgg tggtaaaagc ctccaagtct
     7261 tttgaaaata ttctctaacg tgatagacaa tacgtgtaac gttcagagtg tatttgatag
     7321 cttagaagct ttataaaaag ccctgccatc tctctagcga atttacccac tagagagatg
     7381 atagagctgt tttttggtta ttggatctac ctcatacctc agctaggggg tcttgctggg
     7441 aaagctttga tgagcttgtt gataatggcg aagtaatttt ttaaaggctt tagccgctgc
     7501 tttcgttaat tgcttggagg atttgccatc tcggctaaaa atagggtgct gttgatcatt
     7561 ttgctgctct aaatctggta ctataaatgg actatcaagg tttatcattg ctgtttcaat
     7621 gaaatcaggc tcaaatagct caatgggttc aatatcaagc aatctatgca gatcattgtt
     7681 ttgattggca tagttaaagg aagacccatt gatgagacca ttttgacttg gctgttgagg
     7741 atctagggca gccaagaaat gaccagcctc tgataaaata aattctgagt gaaaatgaat
     7801 taaaatctta taattggctt gggggaaatt gtctgggtat gtgatttgga gctgattggc
     7861 tgtgtctaaa tgactagcta ccttattgtg gtatctggct gattcattaa gactataatc
     7921 agattcgtct agggtagcta ggtatctagc caaggcatca gcatctgttt ttcctgctct
     7981 cccataattg tttctaaccc attctatttg ctgcactgac aggacatagc gcagctgata
     8041 gagcttgcga ttgaaggtct gataaggaat atgctccaaa tgatcataat aaagctgaat
     8101 taatgatgct aattggtccc aaaaggcatc tgtcgggctt aaggacggac tgaattgctt
     8161 gagtaattgc tttgtttcag cgctttgccc acttaattcc tcgggcattt ttacatagct
     8221 caaaagtaag ctgaggtctc ttttagcttc aagcttatgt tgagcccttg gctgcctttc
     8281 ccacatgcga tgaaaagcag gagacccaat gatctgcagg ctctgataaa gctgctcaaa
     8341 gttatagctt gcttgcttag gcttgagatg gcctaggtag cccttttcaa tggcctcata
     8401 ggaccacccg tcctgtgcta gctttttggc ataatgcagc agatctttcc tgagctgaaa
     8461 ctgatcagat aggcttgagg gctgttgttt tatatgccgc ttttcaaagg aaataaccat
     8521 gtccttgtaa gcttggtggc tctgctcaaa ggccagcctt gcttgctcat gctttgcaaa
     8581 gctaacaaca aacagcacaa ataataaaaa catgagcccg ctgtgaatgt atttcatcat
     8641 taggctttac ttaacaaaca tggcatcacc aaagctaaag aagcggtaat gctcatcaat
     8701 ggcatgctta taggcttcaa ggacaaagtc acgacctgca aaagcagaaa ctagcatgac
     8761 aagcgttgac ttgggcagat ggaagttcgt tgaaaaagca tcaacaacct taaattggta
     8821 gcctggctta ataaaaatat tagtccaacc agaatctgct agaatttgcc cttggaattt
     8881 gctgccaatc gtttctagtg tgcgaataga agtagtacca acagcaataa tgcgtccacc
     8941 agcggcctta accttcctaa gggtttgggc ggcctcttca gatagcaggt agaattcaga
     9001 gtgcatgtca tgctcatcga tattatcgac agaaactggt ctaaaggttc ctaggccaac
     9061 atggagggtc aggtagacga ggtgtactcc tttggcttct attttttgca gaagttcctg
     9121 agtaaagtgt agtccggctg taggagcagc tgctgagcca ttttccttgg cgtaaacggt
     9181 ctggtagcgc tcagcgtctg ctagcttttc atggatatag ggcggaagag gcatttcgcc
     9241 tagagtctct aaaatctcta ggaaaatacc atcgtatgaa aactcaacga ttcgaccgcc
     9301 atgctctagc tcttgaatga cccttgcctt taggcgtcca tcaccaaagc tgatctgtgc
     9361 accggcttta agccgctttg cgggcttggc taaaacctcc cattggtctc cctgaatgtt
     9421 tttaagcagc aaaagctcaa catgcccatg tgtttccatt ttttcaccgt ataagcgggc
     9481 aggaaggacc cgagtattgt tcatgaccag tgcatctcct ggctctagtt gatcaatgat
     9541 atggtcaaag tggctatctg tcatggtgtg ctcttgatgg tcgataatca agagcttcga
     9601 gcgatccctt tgttcaagtg gtgtttgtgc aatcagctcc tctggtagct caaaatcaaa
     9661 atcgttggta ttcatcttaa ctcctttacc cttcttgtga ggctatttac aatcagccta
     9721 tttatcctta gagataaatc ctttctatta tatcacttgt ccctggctac gtcacctgtc
     9781 atggttatga gacacataga gatgattgat ggccttttac tccttattag ctagtgcttc
     9841 ttagctgacg acaggggata tgagattatg gcttgacaat aattggtata taccatataa
     9901 tagaatcaca aaaggtctat accaatcaaa aaggagaatc agatgaaaat tattcgtgta
     9961 caggatcagt tagagggtgg caaggttgct tttagcctat taaaggaaag cttggcaaaa
    10021 ggggctacaa ccttaggatt ggcaacaggc agcacaccga ttacctttta tcaggagctg
    10081 gttaatagtg atttagactg ttcagccttg accagtatca acttagacga atatgtcggg
    10141 ctgccggttg aaaatgatca gagctatgac tattttatgc gtgaccagct gtttaacgct
    10201 aagcccttta aggaaagctt tttaccaaac ggcttagctg atgacttaga ggcagaggtt
    10261 aagcgctatg atcaagttat cgcagagcac cctattgatt ttcagattct tggaattggg
    10321 cgcaatggtc atatcggctt taacgagcca ggaacctctt ttgcagaaaa gacgcatgtg
    10381 gtggatttgc aggcttcgac aattgaggct aatagtcgct tctttgctag tattgatgat
    10441 gtgccaaagc aggctatttc aatgggaatt gcttctatca tggcatcaaa aatgattgtc
    10501 ctattggcct ttggtaagga aaaggctgcc gctattaagg gcatggtatc aggtccagtt
    10561 actgaggctt tgccagcaag tgtattacag cagcacggta atgttgtggt tattattgat
    10621 gaggctgccg cttcagagct ggattagact attgctgatg gctaacagct agtctgctat
    10681 ccgttgtgct cttttgatac agtgtaggta tctggctaaa ggtttcttgc tgactttagc
    10741 aaaaaatctg atcagttatt aaaagaggct ctttggcctc ttttttagaa ttaaggtata
    10801 ttgtgataaa ctaatgctat gcgtttagat aaattattag aagtgacagg ctttggttct
    10861 agaaatcaag tgaaacaact catcaaagga aggtctgtct tgattgatgg gcaaccagct
    10921 agagctggtt gtcagagtgt tgattcaggt cttcaagtga taatggtaaa tggcaggcaa
    10981 ataaaggcat ttgctcatcg ctattacctg cttcataagc cagcaggggt tgtgtcagct
    11041 tgctctgata ggaagcacca aactgtcatt gatttgattc gtaaggagga tagagtggcc
    11101 aatctttacc ctataggccg cttagataga gatacaacag ggcttgtcct cttgacggat
    11161 aatggtccat tagggtttcg tatgcttcac ccgaagcacc atgtgaacaa gacctacctt
    11221 gtgactgtca atggctcttt ggctgctgat gcggtgcctt tctttgaaaa tggtgttacc
    11281 tttcttgatg gtactcgctg caagtctgcc gccttgcgga ttataaaggc tgatcaaatg
    11341 gagtcacaag cagaagtaac actctctgaa ggaaaatacc atcagatcaa gaaaatgttt
    11401 ttaagctatg gcttaaaggt cacacagctc aagcgaattg gttttgcaga aatagcgcta
    11461 ggggatttag ctgagggagc ttatcgtcag ctaacagtaa aagaaaaaaa gctcatcaag
    11521 acctatttaa cataaaatat tgttagattt gaagttgact gacaggttaa gtccagtgtt
    11581 tttcggatat atgctataga gagaacgata acaactggag acccctatgc taactgcctt
    11641 agaccaagat caaagagtca tctcgcttac agatggctct tccccctcac gcaagcaagc
    11701 ctttacctgt cctgcttgtg gagctgctgt acgcttgaaa aaaggaagaa ttatccgacc
    11761 ccactttgcc catattagcc taagtcattg ccaatacctg actgaaaatg aatcacatga
    11821 acatctcagg ctaaaggctg atctgtaccg tagcctatct cgctctgaga cagcagaggt
    11881 tgaggcctac ctgcctgatc taaatcaaat tgcagacctt ctggttaata agcacttagc
    11941 cttagaaatc cagtgtagtc agctaccaat caaaaggctg gagcaacgca gtagggctta
    12001 tcaggctaat ggctatcagg tgcgttggct cttaggaaga aagctttggc tgcaaaagcg
    12061 tctgacaggt ttacaaaggc aatgccttta tttttcttgg cagcttggct ttcatctttg
    12121 ggagctcgat gtggaacacc acctgatacg attgaaa
//
LOCUS       DARYYD010000057        12092 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.058, whole genome shotgun sequence.
ACCESSION   DARYYD010000057 DARYYD010000000
VERSION     DARYYD010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12092)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12092)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12092
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.058"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..10364
                     /locus_tag="TV188_001612"
     CDS             <1..10364
                     /locus_tag="TV188_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1534945.1"
                     /translation="DIEKLEMLSNVSSMQDIDRLLFFTSNNVKRILMDISREISKVEE
                     REKISEIQKREQTNSIAERYTNVTDEINGNTEIIENEKERNEGGLEDERNRSIGEEGV
                     HPRKRDLYTDRKRESIRETGRDLQIGENGGWSGSISSEYENAGENKRKQTEPIWQGET
                     EISQRGETRGISDYADGRNFNGSFDRYSGTSGGFPEYRRAEDERSLENDHRNAGSGLS
                     EIHRTEEELGYDTNKNGYGTDHLGIDEYRKENIQKIEQNHVENEEKEVERTSFSFAQN
                     VGVQGRFELPMQQEEIGAVLIHGGNEDNLHLKVLAEYSKEKSMEELADFLQKTFQGGN
                     GYELNGNKVCAWYEMDGIHLSNDVSSRENPMQILPWKDAAIRIGELIDYGKYSTNVEV
                     AEAFSFERAELSEKLWFLKGDLSDEVKNQFLPILNEKQRNGYPEKTEYLTKKLEDKEF
                     RVNLKEEYIEFFKAYKENSNVLRFHNHDLDDISKRLDDLELPRKEFTSTLIELPAIQG
                     FITEDEIDRYLSSGSNVSGGKERIYNFFREAHTTEERANFLKDEYGTGGQTHALSRAR
                     GSSEWHDAKGIKLEKENCKDIILKWNQVVKKIDNLIENGKYIQEDVYTEQESIKTEEE
                     YFDEDTYTEQNSKENEQDWQREQEILLIQDEREVSYEEAEEIYERQAEIEHNAFATGV
                     ENNISSTQSNKDYWIVEFNEGSNLIEKNYAGEVVTKKLLDEIKVLDEKIRVHNKTVGE
                     DEYGEMTDEWVGYSKFYFDHIVDGKVEEHFRMDIGDGNEVNQRDFQYLYEQIEPEKEN
                     KEYGMDSIDSVIKDILEKESMTVVSSKDDYIKLFPYFRNFVYTDGLRLDEYNPFEDDE
                     NISDLIRLTFFQNNDGEYRVVYNNADSLLYSSNVDYFLEKIEAEKVRLEDNIAEIPNE
                     DKIAVKVGNYYAVVEKERVKDISLEETGVRVYPKENNFEGKIYPLYRGSTFEESAKID
                     KLFDEIAIGMKEVNLTDLNDVFYLENQGLYEISSDRVTEEKAGYDFEVASFNEQFPDY
                     YNDIYVYNRNLKIDGANQNIAYINRENEIHFNVNLPEEEKAKVLEIRDKKEVLSTLIF
                     KDVKEVGEYQFHPQSEEFILNELSISEEKLKAPEHITDKIDKKEGYEAELVLDMKNKE
                     LRQHLRYNGYMLSSNVAVSYDSYKAILKNLSYLLDDNHRNIMLTGYVNEQIEKDKAKE
                     ERKEPVYQEGMNVRYQGKEYIISEIQDYKTYKTIKLDDSEGYLNGFITGSEIIPFRNE
                     RELDLEIISTTEKLQEQSINGEDLILLDIEEYNKKGLSVIFQNKEYEITGNNFNPVGM
                     SRLQLVSNTEKLMTEISYTPQRPVANLYAKKDLLERFNLNEKNSEKSIEAKQMSLTDI
                     FEEQDTTKGKEEISSEKERVPVNIGAKVIYQGEEYTVSAFEYNNILEKNDIWLNPVSK
                     NNHQIPIVSFSDREELNEKLIVIDTNLNLGEDKSELLHHSLDVINDKGSVIANQFIVK
                     VDNQNRELTVYSEQNPNSHREFELSFDYLNGLGQIDGDGNNLKLTKHKKETIDKKLKS
                     YHSWKEDGEKRGIPGIAGSSITSPITDEMFWQMKEYEEKLKEEERYAPDDKYLGGIPP
                     INYKITKEDEILPPSERLKNNIEAIKVLKEIEERHSHATKEEQDILSRYVGWGGLSDV
                     FDEEKGGQWKDAREFLKENLSPSEYDAARESTLTAFYTPKIVIDSIYQAVLNMGFESG
                     NILEPSMGTGRFIGNLPDSMKGSKFYGVELDSISGRIASRLYPNAKIQIKGFEETTFS
                     NNLFDVAVGNVPFGEYKIVDREYEKNNFLIHDFFFAKTLDKVRSGGVVAFISSSGTMD
                     KKSEDIRRYISERAEFLGAIRLPNNTFKGEAGTEVTSDIIFLKKRDRLVKLDEEWVKL
                     GTDERGLTYNKYFVDNPDMVLGNMEEISSRFGTSLACVADENSTLKEQLDTAIKNIKG
                     SYEKIELNNEFEVETIPADDSVKNYSYAVIDDKVYFRENSVMQKLNLNKNDEEKVRAY
                     LGIEKALRQVIAYQKEDYSDTEIKEKQGELNRIYDEFSKKYGILNSKANKKLFREDAN
                     YSLLSTLEKLDKEGNFIEKSDIFTKRTIKKAVAIEHTDNLTEALILSISQKGKVNFEY
                     MEKLTEKTRGEIIEGLKGEIFLNLDGFDPSDTTPFSSAIDLGDFSRSYVTADEYLSGN
                     IRDKIEVIDSYIKNVEHEFEQNEQLENIDADVLKQGSETLKKELSSLNYQRQKLLEVM
                     PKELEASEITVRMGATWIPEKDYKSFMFHLLKTSASNRWNIDIKYTNFTGEYRVEGKS
                     IDKGNDLANFTYGTSRVSAYKLIEDTLNLRDTNVYDQVIDENGKKSSVLNQKETMLAR
                     SKQEIIKEEFKNWIFDDIDRRTRLVKEYNEKFNSIRLREYDGSNLTFDGMNPEIELRP
                     HQRDAIARGLFGGNTLLAHEVGAGKTFEMIGIAMESKRLGMSNKSMFVVPNHIVEQFG
                     REFNELYPAANILCATEKDFTPDKRKRFCSRIATGDYDAVIIGHSQFEKIPISKQRQE
                     YELQSQIDEIIDFIEEYKRNRDQKFTVKQLEKTKKGLEAKLKKLNDDYRKDDVVTFEE
                     LGIDKLFVDEVHAFKNLYVFTKMRNVAGITTTDSQKSSDMLMKCRYMDEITGNKGIVF
                     ATGTPVSNSMAELYTMQRYLQYDELKKMHLQHFDSWASTFGETVTAIELNPEGNGYRS
                     KTRFAKFYNLPELMNMVKQFMDIKTADVLNLPVPNAHYETIKTKPTEEQKQILETFSE
                     RADKVRGKQVDSSVDNMLLITNDGKKMALDQRLINPLLPDDPNSKVNTCVNNIFSIWD
                     KYRDEKSTQLVFCDMSTPSSEFNIYDDIKEKLTKMGIPKNETEFIHNAKNNKEKDKIF
                     DKVRKGEIRVLLGSTQKMGAGTNAQNKLIATHDLDVPWRPADLEQRKGRIVRQGNEND
                     DVHIFRYITENTFDAYLFQTLETKQTYISQIMNSKTPVRVAEDIDEATLNYAEIKALA
                     TGNPLIREKMDLDVEVSKLKMLESNFKSNLYKMEDKVVKVYPKEIKSLKEKIENLKKD
                     IEKVEPYREEKLEKYDQTTLENMGENEKQVGIKADKEAISKFTSLTLNGKKYTDKKQA
                     GEFLINKIKGIKKLDDFRSEEVKIGEYRNFDLFAYYDRFSNQYKFNLKGEENHYGEFG
                     TDEIGNITRMDNVLDRMPERLEQTLGKLKDTENQLETAKLEIKKKFPQAELLKEKTLR
                     LAEVNNLLDMGQKGDLKEEKNPLLEEVKEELIHFLNKEYDEAHSIEDFDTMFPDLTDI
                     GLAYTTTPDEKHEIQTSLDLINYKMNTYVDNTLIDSFQYTYDPLNASDTKELIQIKTN
                     IGFWDFNELVYVDEEKLKASLGLEIDDDGNFYDPLSKDMDLDGVMDRYDADFRDSKVQ
                     SFGDLDKKEKASVMDRLGYFKEKIKKGGLQNENIDRKIECKEEVR"
     gene            10845..11804
                     /locus_tag="TV188_001613"
     CDS             10845..11804
                     /locus_tag="TV188_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1534946.1"
                     /translation="MKLEKGDIVKTALSENTTVLDVKDNQAVLFSGTQFVLATGIKEN
                     KESGKFEWDNGRYANDLKSISDIQNNNFETMKETLSFLAEYNHSDFVKGILSLETGIE
                     NEDTLDAAYDNYMNDKIMGLVDEKFYHYIDENEIEAPDLESEIQDKNSVLSDEENVKE
                     DNNTTSEKSNENKEKANTVNINGNIASDIDIKNLTSKDGRDFTVASFAVAENDKEGNV
                     KYTNCLAYNDKVSSVENLKKGDFVHVFGKEKISQGKDGKEYTSLKVYSAKLLKAKEQS
                     KTNQNAKDVKKPSALGKLKEYKEKAGEKSKEQVSVKKDKNIER"
BASE COUNT         4900 a         1440 c         2537 g         3215 t
ORIGIN      
        1 gtgatataga aaaattagag atgctttcaa atgtttcaag tatgcaggat attgacagat
       61 tacttttctt tacttcaaac aatgtaaaaa gaatacttat ggatataagt agagaaattt
      121 caaaagtgga agaaagagaa aaaatttcag aaattcaaaa aagggagcag acaaatagta
      181 ttgcggagcg ttatactaat gttacagatg aaattaacgg aaataccgaa attatagaaa
      241 atgaaaaaga aagaaatgaa ggaggtttgg aagatgaaag aaaccgtagt attggcgaag
      301 aaggagtaca tcctagaaaa cgagatttat acaccgatcg taaaagagag tccattcgag
      361 agacagggag ggacttacag attggagaaa atggaggatg gagcggaagt attagttccg
      421 aatatgaaaa tgccggagaa aataaacgca agcaaactga accgatttgg caaggagaga
      481 ctgaaatatc tcaaagagga gaaacaagag gaatatcaga ttatgctgat ggaagaaact
      541 ttaatggatc atttgataga tattcaggaa caagtggagg atttcctgaa tatagaagag
      601 ccgaggatga aagaagcttg gaaaatgacc acagaaatgc aggatcagga ctttctgaaa
      661 tacacaggac tgaagaagaa cttggatatg acactaacaa aaatggctat ggaacagatc
      721 atttgggtat agatgagtat cgtaaagaaa atatacagaa gatagaacaa aatcatgtag
      781 aaaatgagga aaaagaagtc gagaggactt ctttttcttt tgctcaaaat gtaggagttc
      841 aaggaagatt tgaattacca atgcagcaag aagagattgg tgctgtttta attcatggag
      901 gaaatgagga taatttacat ttaaaggttt tagccgaata ttctaaagaa aaaagcatgg
      961 aagaattagc tgattttctt caaaaaactt ttcaaggagg aaatggatat gaactaaatg
     1021 gaaataaggt ttgtgcttgg tatgaaatgg acgggataca tttatccaat gatgtttcct
     1081 caagagaaaa tcctatgcag attttaccat ggaaagatgc agcaatacgc ataggagaat
     1141 tgattgatta tggaaaatac agtacaaatg tggaggtagc agaagccttt tcttttgaaa
     1201 gagcagaact ttctgaaaag ctgtggtttt taaaaggaga tctaagtgat gaggtaaaaa
     1261 atcagttttt gccaattcta aatgaaaaac aaagaaacgg atatcctgaa aaaacagagt
     1321 atcttacaaa aaaattggaa gataaagagt ttagagtgaa cttaaaagag gagtatatag
     1381 agttttttaa ggcgtataag gagaactcga atgttttaag atttcataat catgatttag
     1441 atgatatatc aaaacgatta gatgatttgg aactgccaag aaaagaattt acctcaacac
     1501 ttatagaatt accagcaata cagggattta tcacagaaga tgaaattgat agatatttaa
     1561 gcagcggtag caatgtatcc ggcggaaaag aaagaatata taactttttt agggaagccc
     1621 atactaccga agaacgagca aattttttaa aagacgagta cggaacagga ggacagactc
     1681 atgctttatc aagggcaaga ggaagtagtg agtggcacga tgctaagggg ataaaacttg
     1741 aaaaagaaaa ttgtaaggat attattttga aatggaatca ggttgtaaaa aaaatagata
     1801 accttattga aaatggaaaa tatattcaag aagatgtata tacagagcaa gaaagcataa
     1861 aaactgagga agaatatttt gatgaagata cctatacgga acaaaactct aaagaaaatg
     1921 aacaagattg gcaaagagaa caggaaattt tgctgattca agatgaaaga gaagtatctt
     1981 atgaagaggc ggaggaaata tatgaaaggc aagcagaaat agaacataat gcctttgcaa
     2041 ccggtgtaga gaataacata tcgtcaactc aaagtaacaa ggattattgg attgtagaat
     2101 ttaatgaagg ctcaaatctg atagaaaaaa attatgccgg agaagttgtt acgaaaaaat
     2161 tgcttgatga aatcaaggtg cttgacgaaa aaattagagt tcataataag actgtcggtg
     2221 aagatgaata cggagaaatg acagatgaat gggtaggtta ttctaaattc tattttgacc
     2281 atattgtaga cgggaaagta gaagaacact tcagaatgga tatcggggat ggaaatgagg
     2341 taaaccaaag agattttcaa tatctttatg agcagattga accggaaaaa gaaaataaag
     2401 aatacgggat ggatagtata gatagtgtca taaaagatat tttagaaaaa gaatctatga
     2461 ctgtggtatc aagcaaagat gattatataa agttatttcc atattttaga aactttgtat
     2521 ataccgatgg tctaaggctt gatgaatata atccgtttga agatgatgaa aatatttcgg
     2581 atttaattcg actgactttt ttccaaaata atgatggaga atatagggta gtctataaca
     2641 atgcggacag tttactgtat tcaagcaatg ttgactattt tttggagaaa atagaggctg
     2701 aaaaggtaag gttagaagat aatatagctg agataccgaa tgaagataaa attgccgtta
     2761 aggttgggaa ttactatgct gttgtagaaa aagaaagagt aaaggatata tccttagaag
     2821 aaacaggagt tcgtgtttat ccgaaagaaa ataactttga gggaaaaatt tacccattgt
     2881 atcgtggcag cacctttgaa gaaagtgcaa aaatagataa acttttcgat gagattgcaa
     2941 taggcatgaa agaggtcaat ttgaccgatt taaatgatgt tttttatctt gaaaatcaag
     3001 gactttatga aatttcatcg gatagggtaa cggaagaaaa agccggatac gattttgaag
     3061 tggcaagttt taatgaacag tttcctgatt actataatga catttatgta tataacagaa
     3121 atttaaaaat agatggtgct aatcaaaaca ttgcatatat caatagagaa aatgaaatac
     3181 attttaatgt aaatctaccg gaagaagaaa aagcaaaggt gcttgaaatt agagataaga
     3241 aagaagtctt atcaactctt atttttaaag atgtaaagga ggtcggcgaa tatcagtttc
     3301 atccacaaag cgaagaattt atcttaaatg aattgagtat atctgaagaa aaattaaaag
     3361 caccggaaca tataacagat aagattgata agaaagaagg ctatgaggct gaacttgttt
     3421 tggatatgaa aaacaaggag ttaaggcagc atttaagata taacggatat atgttaagta
     3481 gcaatgtggc ggtttcctat gatagttata aagcaatact taaaaatctt tcttatctgc
     3541 ttgatgataa tcatagaaat attatgctta ccggctatgt caacgaacag attgaaaagg
     3601 ataaagcaaa ggaagaaaga aaagaacctg tatatcaaga gggaatgaat gtaaggtatc
     3661 aaggcaaaga atatatcatt tcagaaattc aagactataa aacatataaa acaataaagc
     3721 tagatgattc agaaggatat ttaaacggct ttataacggg cagtgaaatt attcctttta
     3781 gaaatgaaag agaacttgat ttggaaatca tatctacaac agagaagtta caagaacaaa
     3841 gtataaatgg tgaagatctt attctgttag atattgaaga atataacaaa aaaggacttt
     3901 ccgttatctt tcaaaataaa gagtatgaaa ttacaggaaa taattttaat cctgtaggaa
     3961 tgagcaggtt acaacttgtc tcgaatacag aaaaactgat gacagaaatt tcatatacac
     4021 ctcaaagacc ggtcgcaaat ctttatgcaa aaaaagatct ccttgaaagg tttaatttaa
     4081 atgagaaaaa tagtgaaaaa agtattgaag caaagcaaat gtctttaaca gatatatttg
     4141 aggaacagga tacaacaaag ggaaaagaag aaatttcaag tgagaaagaa cgtgtacctg
     4201 tcaatatagg ggcaaaggta atctatcagg gagaagaata tacagtaagt gcctttgagt
     4261 ataataatat tttagagaaa aatgatatat ggctaaatcc tgtatcaaaa aataatcatc
     4321 aaattccgat tgtaagtttt tctgacagag aagagctaaa tgaaaagctc attgttatag
     4381 ataccaatct taacttagga gaagacaagt cggaactgtt acatcatagt ttagatgtaa
     4441 taaatgataa aggttctgtg attgccaatc agtttattgt aaaagtcgat aatcaaaaca
     4501 gggaacttac agtatatagt gaacaaaatc ctaatagtca tagagaattt gaactttctt
     4561 ttgattatct aaacgggctt gggcaaattg acggagatgg aaataatcta aaacttacaa
     4621 agcataaaaa agaaaccatt gataaaaaat tgaaaagtta tcattcttgg aaagaagatg
     4681 gggaaaaaag aggaattccg ggaatagcag gttcttctat tacttcacct attactgatg
     4741 aaatgttttg gcagatgaaa gaatatgaag aaaaattaaa agaggaggaa agatacgccc
     4801 ctgatgataa gtatttggga ggtattcctc caatcaatta caaaatcaca aaagaagatg
     4861 aaatcttgcc gccgtccgaa aggcttaaaa ataacataga agccatcaag gtattaaaag
     4921 aaattgagga aagacatagt catgcaacaa aggaagaaca ggatattttg agtagatatg
     4981 tcggctgggg tggactttct gatgtctttg atgaagaaaa gggaggacaa tggaaagatg
     5041 caagagaatt cttaaaagaa aatctatcac cgtctgagta cgatgcagca agggaaagta
     5101 cccttacagc cttttataca ccgaagattg taatagacag tatctatcaa gccgtattaa
     5161 atatgggatt tgaaagtggg aatatcttgg aaccaagtat gggaactggc agatttatag
     5221 gcaatcttcc agacagcatg aaaggcagta aattttatgg tgtagaactt gacagtataa
     5281 gtggtaggat agcaagtagg ctatatccta atgctaaaat acagatcaaa ggttttgaag
     5341 aaacgacttt ttcaaataat ctgtttgatg tagcggtggg aaatgtaccg tttggagaat
     5401 ataagatagt tgatcgtgag tatgagaaaa acaattttct tattcacgat tttttctttg
     5461 ccaaaacctt ggataaagta cgttccggtg gagtagtagc ctttataagt tcaagtggaa
     5521 ctatggataa aaagagtgaa gatatcagaa gatatatttc agaaagagca gagtttttag
     5581 gagcaattag actacctaat aatactttta aaggcgaggc gggtacggaa gtaacaagtg
     5641 atattatttt tcttaaaaag agagatcgac tggtaaaact tgatgaagaa tgggtaaaac
     5701 ttggcactga cgaaagagga ctgacatata acaaatactt tgtagataac cctgatatgg
     5761 tacttggaaa tatggaagaa atatcaagca gatttggaac aagtcttgcc tgtgttgcag
     5821 atgaaaatag tactctgaaa gaacagctgg ataccgccat taaaaacatt aaaggaagtt
     5881 atgagaagat agaattaaat aatgaatttg aagtggaaac cattccggct gatgacagtg
     5941 tgaaaaatta ttcttatgca gtaattgatg ataaggtata ttttagagaa aattccgtta
     6001 tgcaaaaatt gaatttaaat aaaaatgatg aggaaaaagt aagggcatat cttggaatag
     6061 aaaaagcatt aagacaggta attgcttatc aaaaagaaga ttattccgat acggaaatta
     6121 aggagaagca aggggagtta aatcgtattt atgatgagtt ttccaagaaa tacggaattt
     6181 taaacagtaa ggcgaataaa aaactgtttc gtgaagacgc taattattct ttactgtcca
     6241 ctttggaaaa gctggataaa gaaggaaact ttatagaaaa atccgatatc tttacaaaaa
     6301 gaacaataaa aaaagcagta gccatagagc ataccgacaa tctgacagaa gcacttatcc
     6361 tatctatttc tcaaaaaggg aaagtcaatt tcgagtatat ggaaaagctc actgaaaaaa
     6421 caagaggaga aatcattgaa ggattaaagg gagaaatatt cttaaattta gatggatttg
     6481 atccaagtga tacgactcct ttttcttcag ccatagactt gggagatttt tcaagatctt
     6541 acgtaactgc tgatgaatat ttatctggaa atatcagaga taaaatagaa gtaatagatt
     6601 cgtatataaa gaatgtagaa catgaatttg aacaaaatga acagcttgaa aatattgatg
     6661 cagatgtact gaaacagggt agtgagactt taaaaaaaga actgtccagt ttaaattacc
     6721 aaagacaaaa gctgctagaa gtaatgccaa aggagcttga ggcaagtgaa ataaccgtta
     6781 gaatgggagc aacttggata cctgagaaag attataagag ctttatgttc catcttctaa
     6841 aaacatcggc atctaataga tggaatattg atattaaata taccaatttt acaggggagt
     6901 acagagttga aggtaaaagt atagataaag gaaacgacct tgccaatttc acatacggaa
     6961 caagcagagt aagtgcatat aaactgattg aagatacatt aaaccttaga gataccaatg
     7021 tatatgatca agtcattgat gaaaacggaa agaaaagttc tgtactaaat caaaaagaaa
     7081 cgatgcttgc aagaagtaaa caggaaatta tcaaagaaga gtttaaaaat tggattttcg
     7141 atgatataga cagaagaaca aggcttgtaa aagaatacaa tgagaaattc aattcgataa
     7201 ggcttagaga atatgatgga agtaatttaa cttttgacgg aatgaatcct gaaatagagc
     7261 ttagacctca tcaaagagat gcgattgcta gaggactttt cggtggaaac accctacttg
     7321 cacatgaagt tggagctgga aagacttttg agatgatagg aattgctatg gagtctaaaa
     7381 ggcttggaat gagtaacaag tcaatgtttg tagttccaaa ccatattgta gaacagtttg
     7441 gtagagagtt taatgaactg tatccggcag caaatattct ttgtgcaaca gaaaaagact
     7501 ttacaccaga taaaagaaaa agattttgct caaggattgc aaccggtgat tatgatgcgg
     7561 taattatagg gcattcgcag tttgaaaaga ttccaatttc aaagcagcga caggagtatg
     7621 aacttcaaag tcagattgat gaaattatag attttatcga agaatataaa aggaatagag
     7681 atcagaaatt caccgttaag cagcttgaaa aaacgaaaaa aggactggag gcaaaactaa
     7741 agaaattaaa tgatgattat agaaaagatg atgtcgtaac ctttgaagaa ttggggatag
     7801 acaagctatt tgtagacgaa gttcatgctt ttaaaaattt gtacgttttt acaaaaatgc
     7861 gtaatgtagc aggaattaca accacagatt ctcaaaaatc aagtgatatg ctgatgaagt
     7921 gcagatatat ggatgaaatt accggtaata agggtattgt atttgcgaca ggaacccctg
     7981 tgagcaattc tatggcagag ctttatacca tgcagcgtta tctccaatat gacgaactta
     8041 aaaaaatgca cttgcaacac tttgattctt gggcatctac ttttggagaa actgttacag
     8101 caattgaact taatcctgaa gggaacggat atcgaagcaa gacaagattt gcaaaatttt
     8161 ataaccttcc ggaactgatg aatatggtca agcagtttat ggatataaag actgctgatg
     8221 tattaaatct tcccgttcca aatgctcatt atgaaacgat aaaaaccaaa ccgacagaag
     8281 aacaaaaaca aatccttgaa actttttctg agagagctga taaggttaga ggaaaacagg
     8341 tggattcctc tgtcgataat atgcttctga ttactaatga cggaaagaaa atggcacttg
     8401 accaaaggtt aattaatcca ttacttcctg atgatccgaa cagtaaagta aatacctgtg
     8461 taaataatat attcagtatt tgggataaat atagggatga gaagtccaca caattagttt
     8521 tttgtgatat gtcaacacca tcaagtgaat ttaatattta tgatgatata aaggagaagc
     8581 tgacaaaaat ggggattcct aaaaatgaaa cagagtttat tcataacgca aagaacaaca
     8641 aagaaaaaga taagattttc gataaggtac gaaagggtga aattcgtgtg cttctcggtt
     8701 caacgcagaa aatgggagca gggacaaatg ctcaaaataa attgattgct acccatgatc
     8761 tcgatgtacc ctggaggcct gcggatttgg agcagagaaa aggaagaatt gtaaggcaag
     8821 gtaatgaaaa tgatgatgtt catatctttc gttatattac ggaaaatacc tttgatgcgt
     8881 atcttttcca aacacttgaa accaagcaaa cttatatatc tcaaataatg aattcaaaga
     8941 cacctgtaag agtagcggag gatattgatg aagctacatt aaattatgcg gagattaaag
     9001 cacttgcaac aggaaatccg cttattcgtg aaaaaatgga ccttgatgtt gaggtaagta
     9061 aacttaaaat gctggagtcc aattttaaat ccaacctata taaaatggaa gataaggttg
     9121 taaaagtata tccaaaagaa attaaaagtc taaaagaaaa aatagaaaat ttgaaaaagg
     9181 atatagaaaa agtggaaccg tatagggagg aaaaactaga aaaatatgat cagactactt
     9241 tagaaaatat gggtgaaaat gaaaaacaag tggggataaa agcagataaa gaagcaatat
     9301 caaaattcac atctttaact ttaaatggga aaaaatatac cgataaaaag caagccggag
     9361 agttcttaat aaacaagata aaaggaataa aaaaattaga tgattttcgt tctgaggaag
     9421 taaaaatcgg agaatataga aatttcgatt tgttcgcata ttatgacagg ttctccaatc
     9481 agtataaatt caatctgaag ggagaagaaa atcattatgg ggagtttgga acggatgaaa
     9541 tcggaaatat cacccgaatg gataatgtac ttgataggat gcctgagaga ttggagcaga
     9601 cacttggaaa acttaaagat accgagaatc aacttgaaac ggcgaagctt gaaataaaaa
     9661 agaaatttcc acaggcagag cttttaaaag aaaagacgtt aagacttgct gaggtaaata
     9721 atttgcttga tatgggacaa aaaggagatt taaaagagga gaaaaatcca cttttggaag
     9781 aagtgaagga agaactgatt cattttctaa ataaagaata tgatgaagca cacagtatag
     9841 aagatttcga tacaatgttt cctgacttga cagatatagg tttggcatat acgactacac
     9901 cggatgaaaa gcatgagata cagacaagtc ttgatttaat caattacaag atgaacactt
     9961 atgtagacaa tactttaatt gacagttttc agtatactta cgatccactt aatgcaagtg
    10021 atacgaagga acttatacaa atcaaaacga acataggttt ttgggatttt aatgagctgg
    10081 tatatgtgga tgaagaaaag ttaaaagcat cacttggact tgaaattgat gacgatggta
    10141 atttctatga tccgctttca aaggatatgg atttagatgg agtaatggac aggtatgatg
    10201 cagactttag agatagtaaa gtacaaagtt ttggagattt ggataaaaaa gaaaaagcat
    10261 ccgtaatgga taggcttgga tacttcaaag aaaagataaa gaaaggaggc ctacaaaatg
    10321 aaaatattga tagaaagata gagtgtaagg aggaggttag atagttggaa tatcacaaaa
    10381 atattagagc aacggataga gaaatgcaga aactttttga aaatgaggag tataactatt
    10441 ccgtaagata ttttgaaaaa atagaagaaa acttatttaa aacgataatt cgcacaccgg
    10501 agaatataga gtttccaaaa tccaaaacct tgtctataaa cacgataaaa aaactcttag
    10561 aaacagatgt aaatattaac tctatgtata tcagagatga attcactaaa atgaaaaata
    10621 aggtatacga atttaatcaa aaaaaatatc cgggttatga ggatatggat ataaaactaa
    10681 caatatctac tattaagggt atcgaggatt tcgataccct taatgatttt tatgatagtt
    10741 tgaaaaggaa gggatattta gaagcgataa aagaaagtat taaaaatatt attgataaag
    10801 aattagaaga aaacatacaa gtaaaagtac aggaggtaaa aaatatgaaa ttagaaaaag
    10861 gcgatattgt aaaaacagca ttaagtgaaa acacaacagt tttggatgtg aaagataatc
    10921 aggcggtact gttttcaggt actcagtttg tacttgcaac agggattaaa gaaaacaagg
    10981 aaagcggaaa atttgaatgg gataatgggc gatatgcaaa tgatttaaaa agcatttccg
    11041 atatacaaaa caataatttt gaaacgatga aagagacctt atctttttta gcagagtata
    11101 atcatagcga ttttgtcaaa ggaattctgt ctcttgaaac aggaatagaa aatgaggata
    11161 ctcttgatgc tgcttatgat aattatatga atgataaaat tatgggtttg gttgatgaaa
    11221 aattttatca ttatatagat gaaaatgaga ttgaagcacc tgatttagaa agcgaaatac
    11281 aggataagaa tagtgtttta tccgatgagg aaaatgtaaa ggaggacaat aatactacga
    11341 gtgagaagtc aaatgaaaat aaggaaaaag caaatactgt aaatatcaat ggcaatattg
    11401 cttcagatat agacattaaa aatttgacat cgaaagatgg tagagatttt actgttgcaa
    11461 gttttgcagt tgctgaaaat gacaaggagg gaaatgtaaa atataccaac tgtttagcct
    11521 ataacgataa ggtaagtagt gtagaaaatt tgaaaaaagg agattttgtt catgtattcg
    11581 gaaaagaaaa aatcagtcag ggaaaggacg gaaaggaata tacatctctt aaagtttatt
    11641 ctgcaaagct gttaaaagcc aaagaacaga gcaaaacaaa tcaaaatgca aaggatgtaa
    11701 agaaaccgtc agcacttggc aagttaaaag agtataagga aaaggcaggc gaaaaatcaa
    11761 aggaacaggt cagtgtcaaa aaagataaaa atatagagag ataaaattat aaaaatagtg
    11821 ggtaaatagc tgatagggct gtttatccac tatttttctt tgttttttta ttagaaatgg
    11881 aaaaataaag gtttgataaa ctataacagg agcgttatat tataagaaaa agaagattat
    11941 tttgatagag aggtgaatga tatgattgga ttggttattc tttttatagc cttaattata
    12001 ctatatttgg gagtcattct atttgcagga gcaacatttg taaaaattag cctgtttgca
    12061 ctggataaac ttgtggtatt tatagcaagc tg
//
LOCUS       DARYYD010000058        11315 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.059, whole genome shotgun sequence.
ACCESSION   DARYYD010000058 DARYYD010000000
VERSION     DARYYD010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11315
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.059"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            160..747
                     /locus_tag="TV188_001614"
     CDS             160..747
                     /locus_tag="TV188_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534947.1"
                     /translation="MIDKIKNILFDVRLSANKIENEIIFYNGFPEDSVSLSFAGNKCI
                     IEEIHRDNRIRLMETTSEYHAILYCVAILDQIFNTSKNIKITREIKEYIQEGNIIAAE
                     QLLSEKLDPTLFSLGSVEKDKLTLVKENNAYSLIFNDVQILTDLSSLRAYIVLFNYTK
                     KLERAKELYARALHDLPDCKLEFNQFVEYYLIGRN"
     gene            1183..1602
                     /locus_tag="TV188_001615"
     CDS             1183..1602
                     /locus_tag="TV188_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622467.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1534948.1"
                     /translation="MVDNLGNPITEQVTLKAGQIIDRYGSSSGRFTSPIENGVTLPFN
                     KRGLPYPEGYQDYYKYELVMDLTKKNIVNAYYQSEEIIRKQISVEMKKWNLSFDDLAN
                     IQKGEITKVFGQGGGIQIKFPTGVGIYKKMGLLKEIN"
     gene            1603..1926
                     /locus_tag="TV188_001616"
     CDS             1603..1926
                     /locus_tag="TV188_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534949.1"
                     /translation="MDNTNILNWKKDIEEAIKNRGFESLHYVLFDEEKRLPWAFHLYQ
                     KNGKFYVEGRDERSYIIGHSREYRKFDDAKHELLKKLELVIESNRLKKQLGEPTEYPS
                     PLWNE"
     gene            2185..2814
                     /locus_tag="TV188_001617"
     CDS             2185..2814
                     /locus_tag="TV188_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534950.1"
                     /translation="MTTLAGMSPEDSQRYIQWHKYAKAGLSPSDRVRILEISEKAPKI
                     EYLPGKTSDSILAISKGDRPNVEKVYSPDYIGFHRKQFDNGATRFQKFKPNVDYQDGL
                     VGDDLGNSFWLSTKDADIIQEIGKGNNRLYETLLGFDEGYLEDGPLYRLDVSPEVVSQ
                     KGVSIPSGNEKGANSWWRPGGRTYPGNIPEGVMQGISTKKGDHTWHAVN"
     gene            2796..3218
                     /locus_tag="TV188_001618"
     CDS             2796..3218
                     /locus_tag="TV188_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534951.1"
                     /translation="MARSQLEWEDVSQYEEVKGYGQRVWKHQGKYYFVAEEGGIAVQR
                     VVYELPYDLFELLESGERSLGDVHSKLQDGNWPPTEEEKKQSHRKFVIDTPTALIADP
                     TSVSLFSEEELSKLVPIAEQQWIDWKGKLPDDYVSPLK"
     gene            3477..3881
                     /locus_tag="TV188_001619"
     CDS             3477..3881
                     /locus_tag="TV188_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534952.1"
                     /translation="MSKNYTEADVAKLTELTTHNAKTKTALLGYYEANSVTSYEQIAH
                     QNKLTYFDAGSDGWNAMSRVDSKLAQRVNREFLIKQIEKRKTFILTSNPYTAQSIADV
                     SGIGKSYAKEIQILAENGYNIEKFERFWRAYK"
     gene            3878..4306
                     /locus_tag="TV188_001620"
     CDS             3878..4306
                     /locus_tag="TV188_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534953.1"
                     /translation="MSEEQYLPVKESLGYRNLKIALMNVFSIDLDKFTIIEGEFENFG
                     FHLNYNNKEIIIWITSTGKNRQFEYGEGGQLMISLPNPKYPDRSFLDRVTLESLLTDT
                     EKIEAVDYAFGRYEHRLEIALAILKDYLDSDEAKVLLKNE"
     gene            4299..4712
                     /locus_tag="TV188_001621"
     CDS             4299..4712
                     /locus_tag="TV188_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534954.1"
                     /translation="MSEQYLSIKESLGYKNVKQALWTIFSANLDEISIHEGEDENFNF
                     VFTYKNCEMMMGIYDTGKNIQFQAGEGGLFSVSLPNPKYPEQSFQKIVSLSYLISDKN
                     VSENIRWCLGLDLKSVEYVMRVLKDYLDQKCEEEQ"
     gene            4975..5367
                     /locus_tag="TV188_001622"
     CDS             4975..5367
                     /locus_tag="TV188_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623140.1"
                     /note="This protein contains a domain related to
                     Tuberculosis Necrotizing Toxin, which is the C-terminal
                     effector domain of outer membrane channel protein CpnT,
                     and which has a lethal NAD+-glycohydrolase activity;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycohydrolase toxin TNT-related protein"
                     /protein_id="HEL1534955.1"
                     /translation="MTPAFLKTGDLLDRYGESGGTFTSPIVDRKVIPFNKRGLPYPED
                     YQNYHQYKVLKDINMENVEKGYHNLSDSRKKELNLLMNRFDFSLVDIATPQKGMIDLV
                     FGSGGGIQIKLGTSVSWYEKLGLIKEIK"
     gene            5368..5691
                     /locus_tag="TV188_001623"
     CDS             5368..5691
                     /locus_tag="TV188_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534956.1"
                     /translation="MKNLDHQKAELLEAVHQLGYDSLRYSIFSKERPGEWETVIEYDN
                     SQGLYVVYATMDRASYNKKLTFETFQEAKEKFLEKLRLDIQINRYYVEEGMPVNYDSP
                     LWSKN"
     gene            6004..6474
                     /locus_tag="TV188_001624"
     CDS             6004..6474
                     /locus_tag="TV188_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEL1534957.1"
                     /translation="MAYSKEIIAYLVRSGVAKELARDISQDVLLKMLESDLALPPEKI
                     RAWMYRVAVRKYIDRYRRDKAYLDILQRDFFHQERVVEFDHPNYEPLYTAVNELPEKY
                     RWVLSFYYFQDLSVKEMASLLHWSVSSVKVNLMRGRRCLKEKLKKAGYTYDDFN"
     gene            6458..7551
                     /locus_tag="TV188_001625"
                     /pseudo
     CDS             6458..7551
                     /locus_tag="TV188_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623137.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
     gene            complement(7845..10991)
                     /locus_tag="TV188_001626"
     CDS             complement(7845..10991)
                     /locus_tag="TV188_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534958.1"
                     /translation="MKLKKIIALACVGILTLHQLSPAIVYATTDTSDGIAATVNAGDT
                     AAPSAEAKLSQLMTDTQALFTDNSCSKLASGVTQEKIDTLKQKATDSTEPEKEQILGL
                     LDKAASLLQQFTLQGLGNGVFAQLYFYADGSYTASLVTKRGQPHSYFSTNYATITILN
                     NKKETVYSKEYAGNVSQVAQTEELELKEGYYLIINKQEPNRFYTNHNDALKQNNTNPY
                     TYVVRDGQLERIDDSNRTLRFLGLGNAEYATLRVDYNASTLTLKTKQTKPHVYFSGSY
                     EKLEVLDTENQVIYTKDFIGTQVLEAKTETIPFKVGYKIRLTGSEHHTRVKFYDDYAV
                     EAPLTLSKNQATLKLLDHSLELMRSKTGSELESEVLTLFTDESTSKLASGVTQEKIDA
                     LRKKATDSTEPEKEQILSLLDKAASLLQQFTLQGLGNGIFAQLYFYADGSYTASLVTK
                     KGQPHSYIANNYATLTILNEKKETVYAKEYVGNVSQTAKTESLTLKEGYYLVITKQEP
                     NRFYTNHNDALKQNNTNPYTYVVRNGQLERIDDSNRTLRFLGLGNAEYATLKVDYNAS
                     TLTLKTKKAKPHVYFSGTYEKLEVLDLKDKVVYTQDFIGNQALTAKTETIPFKVGYKI
                     RLTGSEHHTRVKAYDEENKAVSLSLPKNKAEIRITKGGLASVFALEAKATNTLVQAVE
                     KRLTKEKIEDFKKQDDKHKAFIDWLLKDNEAMQLYLGAGYAHSAAQGGMSSYQFKNTY
                     NLTNELEALELWFKIWDKYETSHQGIQLKMAIAVALEFNKPVGAWYNESRKIDPLERF
                     ATFAEAEQGNILFEDFYSLTVEQIRNVVNAKITDEDMKWLRQYVETNKPAMINRNDIT
                     KGYSLISYVMTNPETGVSVQSSGFYGPNPTIKEVIKYGGVCGAMSKLSSVLAQAYGVP
                     AFPIGQPGHCAYIYLNADHTYQLGYDVSGWTGCGNYNTTLPYVQIHNVYSLNIDAYNA
                     SEYERYKAEAATDKETKLNHLDAALKAEPLNYKAWNDKLALVASDQTAYQSTLNDMKS
                     ALKDYPVIINNLEKDTKQ"
BASE COUNT         3581 a         1890 c         2429 g         3415 t
ORIGIN      
        1 tcagaggata ctatgtttat ttgagtatat gctggtgagg tttcagatca atttgtgaag
       61 tataaaccta atggagttga taaatatagt attcaagagc taatggatat ggttttttag
      121 atgacataac tgatttggtg aagaaaggag aaattagaat tgattgataa aataaaaaac
      181 attctttttg atgttaggct gagcgcaaat aaaatagaaa atgaaataat attttataat
      241 ggctttcctg aagatagtgt atctttatca tttgcgggta ataaatgtat cattgaagaa
      301 attcatagag ataatagaat caggttaatg gaaacaactt cagaatatca tgctatttta
      361 tattgtgttg caattttgga ccagatcttt aatactagta aaaatatcaa gattacaaga
      421 gaaatcaaag agtatataca ggaaggaaat attatagcag ctgagcagtt gctctcagaa
      481 aaattggatc ctactctttt ttcattaggg tctgtggaaa aagataaatt aacccttgta
      541 aaagaaaata atgcctatag tttaatattt aatgatgtgc aaattctaac tgatttaagt
      601 tcattacgtg cttacattgt tttatttaat tacactaaaa aacttgagag agcaaaagaa
      661 ttatatgcta gagcactaca tgacttgcct gattgtaagt tagaatttaa tcagtttgta
      721 gaatattatt tgataggaag gaattaataa aagaactatt gaaataccat atggcatttt
      781 gagttcagat gcccagtcat ggcaggaggc agcgaacaag atgctcagcg agctacatta
      841 gtaggcaata tcctaggagg attcgccgcc tcaagcgtcg ccagacggtt cagcttgaat
      901 gagccaatag cagctagggt gacgaaaccg acctacagcc gccggcagct tttgaagaac
      961 cttgagaaca gcaggctggc aagagaaagc tcgaggtttg atgattatct tcgaagagaa
     1021 taccggttaa agggaaggta ttttgcagaa agaaccacta tttcaaatgg aaagataggt
     1081 tatctttcat ctgactattt tgaaggcaag caaattccgg ttcgctctag agcttttgtt
     1141 gacgaagcag gccatattaa atggccaaat gccgatggct ttatggtgga taatttaggt
     1201 aatcctataa cggagcaggt cactctcaaa gcaggtcaaa tcattgatcg atatggatca
     1261 agtagtggtc gatttaccag tccgatagaa aatggggtga cattaccatt taataaacgt
     1321 ggattaccct acccagaagg atatcaagac tattataagt acgaattagt aatggatttg
     1381 acgaagaaaa atattgttaa tgcgtattat caatctgaag agattataag aaaacaaata
     1441 tctgtagaaa tgaaaaaatg gaatctttcc tttgatgatt tagctaatat tcagaagggt
     1501 gagattacca aagtatttgg gcaaggtgga ggaattcaga ttaaatttcc gacaggtgtt
     1561 ggtatttaca agaaaatggg tttattaaag gagattaact agatggataa tacaaatata
     1621 ttgaattgga aaaaagatat tgaagaagca attaaaaatc gaggttttga gagtttacat
     1681 tatgttttat ttgatgaaga aaagcgactt ccttgggcat ttcatcttta tcaaaaaaat
     1741 ggaaaattct atgttgaagg aagagatgag cgatcatata tcattggtca tagcagggaa
     1801 tatcgtaaat ttgatgatgc caagcatgaa ttgcttaaaa aattagaatt agttatagaa
     1861 tctaatcggt taaaaaagca gttaggtgaa cctacagaat atccctcacc actatggaat
     1921 gaatgagttt catgtattgt atgccatggc accaagcttt taggaggcag cgagcaagac
     1981 gcccaaagag caacattagt tgggaatatc ctaggaggac ttgccgcctc aagcgccgct
     2041 agaaggttca gcttgaatga gccaatagca actagggtga cgaaaccgac ccacaaccgc
     2101 cagcagcttt tgaagaacct tgagaacagc agactggcaa gagaaagctc aaggtttaag
     2161 aattatgtag caagagaaaa attcatgaca acccttgcag gcatgagtcc tgaggatagt
     2221 cagcgctata ttcaatggca caaatacgca aaggctggac ttagtccgtc agatcgagta
     2281 aggattctag aaatatctga gaaggcaccg aagatagagt atcttccggg aaaaacatca
     2341 gatagtatat tggcaatatc caagggtgat cgtccaaatg tggagaaagt ctacagtcca
     2401 gattatattg gatttcatag aaaacaattt gataacggtg caactagatt tcagaaattt
     2461 aagcccaatg tagattacca agacggttta gttggtgacg atttaggcaa tagtttttgg
     2521 ttaagtacca aggacgcgga tattatccag gagataggaa agggaaataa ccgtctttat
     2581 gagacactct taggctttga tgaagggtat ttagaagatg gtcccctcta tcgcttagat
     2641 gtttcaccag aagttgtttc acaaaaaggt gtttcaatac caagtggtaa tgaaaaaggg
     2701 gcaaatagct ggtggcgtcc tggaggtcgt acttatccgg ggaatatacc agagggagtt
     2761 atgcaaggta tcagtacaaa gaaaggagat cacacatggc acgcagtcaa ttagagtggg
     2821 aagatgttag tcaatatgag gaggtaaagg gctatggtca aagggtgtgg aagcatcaag
     2881 ggaaatatta ctttgttgcc gaagaaggtg gcattgctgt tcaacgagta gtatatgagt
     2941 taccgtatga cttatttgaa ttgttggaaa gtggagaacg tagtcttgga gatgttcatt
     3001 caaagctaca agatggtaat tggccaccaa cagaagagga aaagaagcaa agtcatagaa
     3061 aatttgttat tgacacacca actgcgctga ttgcagaccc tactagtgtg tctctgttct
     3121 cagaagaaga attatcaaaa ttagtgccaa tcgctgaaca acagtggata gattggaagg
     3181 gaaagctgcc agatgattat gtcagtcctt tgaaataatg tttaagatag cggagccgag
     3241 attagctctg ctattttaaa gcatgttctt aataattagc ctgcgacagc ttatcaggga
     3301 gtagctcgtc accttgaagc caatgccaag cgtctccaag cgccgccaga aggttcagct
     3361 tgaatgagcc gatagcagct aaagtgacga aatcagcgaa aataaccctt tctgaaaagg
     3421 tactagacac aaaggttcgg tttgatgagt ctcgcattgt ggcttacgca gaaagtatga
     3481 gtaagaacta tacagaagct gacgtggcca aattaaccga gctgaccacc cacaatgcaa
     3541 aaaccaaaac agctttgctg ggatattacg aagcaaacag cgttacttcg tatgaacaaa
     3601 ttgcacatca aaataagtta acttactttg atgccggaag tgatggttgg aatgcgatgt
     3661 cgagagtgga ttctaagcta gctcaaaggg ttaatcgtga atttttgata aaacaaattg
     3721 agaaaagaaa aacatttata ttaacgtcta atccatatac tgctcaatca atcgcagatg
     3781 ttagtggtat cgggaagtct tatgctaaag aaattcagat tttagcagaa aatggatata
     3841 atattgaaaa atttgaaagg ttttggaggg catataaatg agtgaagaac agtatttacc
     3901 agtaaaggaa agcttaggat atcgtaactt aaaaatagct ttaatgaatg ttttttcaat
     3961 agatttggat aagtttacaa ttattgaagg agaatttgaa aattttggtt ttcatttaaa
     4021 ttataacaat aaagaaatca taatctggat tacatcaact ggtaagaata gacaatttga
     4081 atatggagaa ggaggacaat tgatgatttc acttcctaat ccaaagtatc ctgatagatc
     4141 ctttcttgat agggtaacct tagaaagtct tttaacagac accgaaaaaa tagaagcagt
     4201 tgactatgct tttggaagat acgagcatcg tctcgaaata gcgttggcca ttctaaaaga
     4261 ttatttagat tcagacgaag caaaggtttt attgaaaaat gagtgagcaa tatttatcaa
     4321 taaaagaaag cttaggttat aagaacgtta aacaggcttt atggactatt ttttcagcca
     4381 accttgatga aatttctata catgaaggag aagatgagaa ttttaacttt gtctttacat
     4441 ataaaaattg tgaaatgatg atgggaattt atgatactgg taagaatatt caattccaag
     4501 ctggagaagg tggtttattc agtgtaagtt tacctaatcc taaatatccg gagcagtcat
     4561 ttcaaaaaat tgtatcactt tcttatttaa tttctgataa aaatgtaagt gaaaatataa
     4621 gatggtgctt aggactggat ctgaaatctg ttgaatatgt tatgcgtgtt ttgaaggatt
     4681 atctggatca aaaatgtgaa gaggaacaat aattctaatc acttctggag ggcatataga
     4741 tgagtgaaga acagtattta ccaatacctt cgaagagaat accagttaaa gggaaggtat
     4801 tttgcagaaa gaatcaccat gccagatgga aaatatgctt atctgtccaa tgacattgat
     4861 aaagctaccg gaacaccaat tcctgtccga tatagaaatt accttaaggc tgatggttct
     4921 attaattggc caaactataa tggctttagt cttgatgtaa agggaaggcc tatcatgact
     4981 ccagctttcc taaaaacagg tgatttactt gatagatatg gagaatctgg aggaacattc
     5041 acaagtccaa tcgttgaccg taaggttata ccatttaaca agcgaggctt accataccca
     5101 gaggactatc aaaattatca tcaatataag gttcttaagg atattaatat ggaaaatgtt
     5161 gaaaagggtt accataattt atctgatagt agaaaaaaag agttaaatct attaatgaat
     5221 agatttgatt tttcactggt agacatagca actccacaaa aaggaatgat tgatcttgtc
     5281 tttggctctg gtggaggtat ccaaataaag ttaggaactt ctgtaagttg gtatgaaaaa
     5341 ttgggtttaa ttaaggagat aaagtagatg aaaaatttag atcatcaaaa ggcagaacta
     5401 ttagaagcag tccatcaatt aggttatgat agtctaaggt attccatttt ttctaaagag
     5461 agaccaggag aatgggaaac tgtcattgaa tatgataata gtcaaggctt atatgttgtg
     5521 tatgcaacta tggatagagc tagttataat aagaaattaa catttgaaac atttcaagag
     5581 gctaaagaaa aatttcttga aaaacttcgg ttagatatcc aaatcaacag gtactatgtg
     5641 gaagagggca tgcctgtaaa ttacgattct cctttgtggt caaaaaatta atacaagtaa
     5701 aggagaatat acatggcatg tagtcaatta gagtgggaag ataaatgaaa taatggtcct
     5761 aggaaatgtc ccgactggaa actatcttat gaactctttt atggaaaagt gttgcactta
     5821 atttgaattt tgtcatataa aaaagcccta taatctccat ggtggactta cccactacag
     5881 aaatgataga gctaaaaatc tccatttggg gatttttttg taaccaaatg aagcagtcgt
     5941 tcgttatata ggtgaagaag ggaggggaga attatcaggc tagatgctta tgaaagagag
     6001 ctagtggctt attctaagga aattattgcc tacctagtga gatcaggtgt tgctaaggag
     6061 ctagcgcgtg atattagtca agacgttttg ttaaaaatgc ttgagagtga ccttgctctg
     6121 cctcctgaaa aaatacgtgc ctggatgtat cgggttgctg ttagaaaata cattgaccga
     6181 tataggcggg ataaggctta cttggatatt ctccaaaggg atttttttca tcaagaaagg
     6241 gttgttgaat ttgaccaccc caattatgag ccgctttata cagcagtcaa tgaattgcca
     6301 gaaaaatacc gctgggtctt gtcgttttat tactttcagg acctatcagt caaggaaatg
     6361 gcgtctctgc tccattggtc agttagcagc gtcaaggtca acttgatgcg gggaagacga
     6421 tgccttaaag aaaaactaaa gaaagcaggt tatacctatg acgatttcaa ctgattttga
     6481 agccattgct aagcgccata aaaggaggct gacccttaaa tatgtagtgc tgagtgctgg
     6541 cttagcctta gtagctcttg tactgggcta tatgggatta aatcgattga caagcatgaa
     6601 cggtcagtat ttaatggctt attacaacaa tcgtatacaa attgcttatc ccaatattga
     6661 tgttaatagc ttcttttaca atgccaattc gcagtttact ggtgagcttc attctgagcg
     6721 gaccaaggat attgctggga tttcggtacc gtttgagccc tatagagctc cttattcctt
     6781 gcctttaccc agagagagat ggactatacc aatgaatacc ttgtttcagg tgatgatgga
     6841 cggtcaacct acacaagagg tacacattat aaaatgcctc gcttcttcaa cactaaggcc
     6901 aagatcacag aaagcaacta tgacaagcca acgcaggacc tagactttat tgctgacatg
     6961 tcaggacagg cgattgaggt agccattacc tttgataagc cttatttatt atcggacata
     7021 gtcaagctgg ttccagacca gctaaagctg aattggatct ggattggcac agaaagcagc
     7081 tatgacacct cagggctttt ccctgctaat ttatatggct ttaagccaaa ctggaaggct
     7141 aatatgacgt acaaggagca aaagcagtta gataaaaaaa taaacgatat cctaaaaaag
     7201 gacagcgagg ctgatttgtc taagcttaat gctgcttacg ataagccagt cagtccaacg
     7261 gtggctctgc aaaattccta tgataccttc aggcactatc tacaagaggc agctgacaat
     7321 cattggatta atagtaccta tggcggcgct aatggatctc atttaagtga gcaggaggat
     7381 gtggccttat ttctaaaaaa caatcgcaat gtcaaaacag ctaagtttgc tggcattatt
     7441 ttaaccggca aggctgagca gtttgcctcc ttaaaaacag ctgattggat ttatgcctca
     7501 aatattggtc agtctgttgc cattcagccc tatcatcagc taaccaagta aataaaaagc
     7561 ttgtgctgct aatcaagcgc atcaggcaaa ggataaaaag cctaaaagag attagattaa
     7621 gtaaatcgat gcttaaaaaa gctccagctt aggtcaaaag acgtcaaaag gctcttggag
     7681 gtcagtgttt gatcactgct tctggggctt tttgctttgc tgcaatcaaa aaagcttgaa
     7741 gcagctctct caattgagca tgtccttcaa gctgagactc ttatatttta tagtatttgt
     7801 aagtatagtt ttagctagcc ttcttttaag cccaagggct tagcttactg tttagtatct
     7861 ttttctaaat tattgataat aactggataa tccttcaatg cagacttcat gtcatttaga
     7921 gtgctttgat atgctgtttg gtctgaggct accaatgcta gcttgtcatt ccatgcttta
     7981 tagtttaatg gctctgcctt tagagcagca tctaaatgat taagcttagt ctccttgtca
     8041 gtagctgctt cagccttata tcgttcatat tctgaggcat tataagcgtc tatattaaga
     8101 gagtagacgt tatgaatttg gacataagga agtgttgtgt tgtagttacc acagcctgtc
     8161 cagcctgaga catcatagcc gagctgatag gtatggtcag catttaagta gatataagca
     8221 cagtgacctg gttgtccaat aggaaaggct ggtacaccat aagcctgtgc tagcacacta
     8281 cttaatttag acatagcacc gcagacacca ccatatttga tgacttcctt gatggttgga
     8341 tttggtccgt aaaagccaga gctttggacg ctcacacctg tttctgggtt ggtcatgaca
     8401 tagctgatca gtgaatagcc cttagtaata tcattacggt taatcatagc aggcttattg
     8461 gtttcaacgt attgtcttaa ccatttcatg tcctcatcag taattttagc attgacgaca
     8521 tttcggattt gctcaacagt taagctgtaa aaatcttcaa ataggatatt gccctgctca
     8581 gcctctgcaa aggttgcaaa tctttcaagt ggatcaatct tgcggctttc attgtaccaa
     8641 gcacctacag gcttgttaaa ttccaaggca accgcaatgg ccattttgag ctgaatacct
     8701 tgatgtgagg tttcgtattt atcccaaatc ttaaaccaca attccaatgc ttctagctca
     8761 ttggtgaggt tataggtgtt tttgaattgg tatgatgaca tgccaccctg tgctgcagaa
     8821 tgggcatagc ctgcaccaag atataattgc attgcttcat tatctttgag caaccaatca
     8881 ataaaggctt tatgcttgtc gtcttgcttc ttgaagtcct cgattttttc cttggttagt
     8941 cttttttcaa cggcttgtac gagtgtatta gtagctttag cctctagtgc aaatacagaa
     9001 gccaaaccac ccttggtgat tcgaatctct gccttatttt tagggaggct aagagaaaca
     9061 gccttgtttt cttcatcata ggctttgact ctagtatggt gctcactacc agttaggcgg
     9121 atcttgtagc ccaccttgaa gggaatagtc tctgttttgg ctgttagagc ttggtttcca
     9181 ataaagtctt gtgtgtagac aaccttgtct tttaggtcta agacctcaag cttttcgtaa
     9241 gtcccactga agtaaacatg tggcttagcc tttttggttt tgagagttaa ggtagaggca
     9301 ttgtagtcaa cctttaaggt tgcgtattct gcattgccta agccaaggaa gcgcagcgtt
     9361 ctattactat catcaatacg ctcaagctgc ccgtttctca ccacataagt gtaagggttg
     9421 gtattgtttt gctttagagc gtcattgtgg ttagtgtaga agcggttagg ctcctgctta
     9481 gtgatgacta ggtaatagcc ttccttgaga gtaaggcttt ctgttttagc tgtttgggaa
     9541 acattaccca cgtattcctt agcataaacg gtttcttttt tctcattgag aatggttagg
     9601 gtagcgtaat tgttagcgat gtaagagtga ggctgtcctt ttttagtgac taagcttgca
     9661 gtgtaactgc cgtcagcata gaagtagagc tgagcaaata taccatttcc tagcccttgt
     9721 agagtaaatt gctgtagcag gctagctgcc ttatcaagta aacttaggat ttgctctttt
     9781 tcaggctctg ttgagtcagt cgcctttttc ctaagagcat ctattttttc ttgtgtgaca
     9841 ccacttgcta gcttacttgt agactcatct gtaaatagag tcagtacctc agactcaagc
     9901 tctgagcctg ttttagacct cattagctct agtgagtggt caagaagctt taaggttgct
     9961 tgatttttag agagtgttaa tggcgcttct accgcataat catcgtagaa tttcactctg
    10021 gtatggtgct cactacctgt caagcggatc ttgtagccta ctttaaaagg aatagtctct
    10081 gttttagctt cgaggacttg agttccaata aagtcctttg tgtagattac ttgattttct
    10141 gtatccagca cctcaagctt ttcataagat ccactgaagt aaacatgtgg cttggtctgc
    10201 ttggttttga gggttagggt agaggcattg taatcaaccc ttaaggttgc atactctgca
    10261 ttgcctaagc caaggaagcg cagcgttcta ttactatcat caatacgctc aagctgccca
    10321 tctctcacca cataagtata agggttggta ttgttttgct ttagagcgtc attatggtta
    10381 gtgtagaagc ggttaggctc ctgtttattg atgatgaggt aatagccttc ttttagctca
    10441 agctcttctg tttgtgctac ctgagaaaca ttgccggcgt attcttttga atagacggtt
    10501 tccttcttgt tattaagaat ggttatcgta gcgtaattag tagagaaata agagtgaggc
    10561 tggccccttt tagtgaccaa acttgcagtg tagctgccat cagcatagaa gtaaagttga
    10621 gcaaagacac cattgcctaa cccttgtagg gtaaactgct gtaataggct agctgcctta
    10681 tctagtagac ctaggatttg ctctttttca ggctctgttg agtcagtcgc cttttgcttt
    10741 aaggtatcta ttttttcttg tgtgacacca cttgccagct tactgcagga gttatctgta
    10801 aataaggctt gggtatcagt catcagttgt gatagcttag cctcggcaga aggagcagct
    10861 gtatcacctg cattaactgt agcggctatt ccatcagaag tatcagtagt tgcataaaca
    10921 attgctggag agagctgatg taatgttaat attccaacac atgctagtgc tattattttc
    10981 tttagtttca tcgttataaa gtccttttac aataaaataa agtgattcaa aactctggga
    11041 aaagaatagc tagccttaaa actatactcg caaatactat aaaatagaaa gactatttac
    11101 cctccttagc tcttgatgct gtggtgatga tattgttacg gtgctaaaaa tcctatccct
    11161 cctttttgac tattttgtct ctcttattcc ataatattaa aaaatcagaa tatgtcaata
    11221 tatattttct ttaatcctag aaatgataaa taggtttgga aaattcttaa tcattgatag
    11281 ccttaaaacg ttattataac agtgttttgt gattt
//
LOCUS       DARYYD010000059        11298 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.060, whole genome shotgun sequence.
ACCESSION   DARYYD010000059 DARYYD010000000
VERSION     DARYYD010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11298
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.060"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(72..2753)
                     /locus_tag="TV188_001627"
     CDS             complement(72..2753)
                     /locus_tag="TV188_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEL1534959.1"
                     /translation="MSKEQRHEAFYTQSEETVLAQLESSRKGLTSTEAQQRLAAYGRN
                     ELDEGEKRSLFMKFLDQFKDLMIIILVAAAFLSVVTEGMEGLTDAIIILAVVILNAAF
                     GVYQEGQAEAAIEALKSMSSPLARVRRDGHVIEVDSKELVPGDIVLLEAGDVVPADMR
                     LLEVNSLKIEEAALTGESVPVEKDLSREVSADAGIGDRVNMGYQNSNVTYGRGMGVVT
                     NTGMYTEVGHIAGMLANADETDTPLKQNLDNLSKILTYAILVIAAVTFAVGVFLRGQR
                     PLEGLMTSVALAVAAIPEGLPAIVTVVLSLGTQVLAKRNAIIRKLPAVETLGSTEIIA
                     SDKTGTLTMNQMTVEKVYTNGALQESSADIAFDNNTLRVMNFANDTKVDPAGKLIGDP
                     TETALVQFGLDHRFDVREALVSEPRVAELPFDSDRKLMSTIHKQADGRYFIAVKGAPD
                     QLLKRVTQIEENGDIRPITEADKQTILATNKDLAKQALRVLMMAYKYTEVIPVLETEV
                     VEAELIFSGLVGMIDPERPEAAQAVKVAKEAGIRPIMITGDHQDTAEAIAKRLGIIEE
                     DGVDHVFTGAELNELSDEAFQKVFRQYSVYARVSPEHKVRIVKAWQNEGKVVAMTGDG
                     VNDAPSLKTADIGIGMGITGTEVSKGASDMVLADDNFATIIVAVEEGRKVFSNIQKTI
                     QYLLSANMAEVFTIFLATLFGWDVLQPVHLLWINLVTDTLPAIALGVEPAEPGVMKHK
                     PRGRQSSFFDGGVKEAILYQGALQTILVLGVYGFALMFPEHTSYHDVHADALTMAYVT
                     LGLIQLVHAYNVKSVYQSIFTVGLFKNKLFNYSIPVAFVALMATVVVPGFNKFFHVTH
                     LTLTQWLVVIVGSLLMVVLVELVKAIQRSLGQDDKAI"
     gene            complement(3101..3487)
                     /locus_tag="TV188_001628"
     CDS             complement(3101..3487)
                     /locus_tag="TV188_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEL1534960.1"
                     /translation="MKIEINNKISYGQETELIKEIHTGDLRQKADATYLIYQNNNNER
                     VVIKFNAAELTMSRFSKPQSVMRFLANKKALIAIPTPVGIQQFLTDTSHFHLDHGQQT
                     VTLDYALLQPSTETAFAHYHLEIKWY"
     gene            3568..4869
                     /locus_tag="TV188_001629"
     CDS             3568..4869
                     /locus_tag="TV188_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003050030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEL1534961.1"
                     /translation="MNEKVFRDPVHNYIHVNHQLIYELINTKEFQRLRRIKQVPTTAF
                     TFHGAEHSRFSHCLGVYEIARRVTEIFEEKYADLWHKEESLVTMTAALLHDIGHGAYS
                     HTFETLFDTDHEAVTQDIITSPETEINAILTRYSPDFPDKVASVINHTYPNKQVVQLI
                     SSQIDCDRMDYLLRDSYFSAANYGQFDLMRILRVIRPVKDGIAFDLSGMHAVEDYIVS
                     RFQMYMQVYFHPASRAVELILQNLLKRAKALYPSQQDYFQKTAPGLIPFFEKSFTLAD
                     YLCLDDGVLNTYFQQWITSEDHILSDLSSRFINRKILKSVTFDQESQQDLERLRKLVE
                     SVGFDPDYYTGIHVNFDLPYDIYRPELENPRTQIEMIQKDGSRAELSQLSAIVKALTG
                     TSYGDRRFYFPKEMLELDDLFTSDKEAFISYISNGHFHFNN"
     gene            5094..5903
                     /gene="yidA"
                     /locus_tag="TV188_001630"
     CDS             5094..5903
                     /gene="yidA"
                     /locus_tag="TV188_001630"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEL1534962.1"
                     /translation="MSIKLVAIDIDGTLLTDDRRVTNDVFDAIQEAKAQGVHIVIATG
                     RPITGVISLLEQLQLNQKGDHVITFNGGLIQDTATGEEVVKELMTYDDYLDIEYLSRR
                     LGVHMHAITTEGIYTANRNIGKYTVREARLVDMPVFYRTPEEMADKEIVKMMMIDEPN
                     LLDEAIKQIPQAFYDTYNIVKSTPFYLELTPKTVSKGTAIGHLAKKLGIDMSQTMAIG
                     DAENDRAMLEAVANPVVMENGAPELKKLAKYITKSNNDSGVAHAIRKWVLN"
     gene            5903..7117
                     /locus_tag="TV188_001631"
     CDS             5903..7117
                     /locus_tag="TV188_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase FemX"
                     /protein_id="HEL1534963.1"
                     /translation="MYTYKIGISAKEHDQFVLSHPQVNLLQSAHWAQVKDNWEHELIG
                     FYQDDKQVAAAACLIKRLPLGMTMIYIPRGPIMDYSDFELVNFVMTSLKAYGKSKRAL
                     MIKYDPSLFISQALIGEERKDNDFTLSIIDFLKTIGVEWTGRTKELEQTIQPRFQANI
                     YAKDFKLQSLSKKARQSIRTAQNKGVEIIIGSTELLEDFSALMKKTEERKHISLRGIS
                     YYDKLMTTYANQAYITMARLNLPKQKALIQQQLEEALSNQQAFTQHSKPGKVAENQNT
                     IKRLEKELAFLDKEIQAGKSLVPLAATLTLIYGQTSENLYAGMDNDFRQYQAALLTWY
                     HTAEEAFKRGCQWHNLGGVENQLDGGLFQFKARLNPAIEEFAGEFSIPVGPISKVAMI
                     AYNLRKKLRSNP"
     gene            7117..8352
                     /locus_tag="TV188_001632"
     CDS             7117..8352
                     /locus_tag="TV188_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1534964.1"
                     /translation="MALDIIDKETFGSFCSQMKYKSFIQSIEMAELLQKRGYQTQYLA
                     ISDQKNIKIAAILYSIPMTGGLRMEINSGPVVADTTYTTAFYKALQDYAKQQGALELV
                     IKPYDTYQTFTSDGHPNDDEKPELIKTLTELNFTHDGLLTGYHNGEGDWHYVKDLSGL
                     TSANVINSFSKKGKALLKKAKTFGIKLHKLNRDELTQFKEITAATSSRRDYTDKSLSY
                     YQDFYDSFGDSCEFMVATLNFDDYLTNLEHSQDKLKQRISKLEADLVKKPKSEKKQNQ
                     LRELSSQFDTFQVRIAEAQELIVKYGKKDIPLAGSLFVYTPQEAVYLFSGSYPEFNRF
                     YAPALLQEHVMLRAIEKKISCYNFLGIMGEFDGSDGVLRFKQNFNGYITRKMGTFRYY
                     PKPFKYKAIQAIKTMLGRS"
     gene            complement(8561..9319)
                     /locus_tag="TV188_001633"
     CDS             complement(8561..9319)
                     /locus_tag="TV188_001633"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEL1534965.1"
                     /translation="MSRKPIIAGNWKMNKNPQEAKAFVKAVVSKLPSNDLVDVAVAAP
                     AVDLVTTIEAAKDSVLKVAAQNCYFENSGAYTGETSPKVLADMGADYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGLTPIICCGESLETYEAGKAVAFVGAQVSAALEGLSAEQV
                     ASLVLAYEPIWAIGTGKSATQEDAQSMCKAVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NIKEYMACPDVDGALVGGASLEADSFLALLDFVN"
     gene            complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TV188_001634"
     CDS             complement(9585..10781)
                     /gene="tuf"
                     /locus_tag="TV188_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEL1534966.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETATRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMELMDTVDSYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGTVRVNDEIEIVGIRDEIKKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGI
                     VSEIEA"
BASE COUNT         3394 a         2572 c         2251 g         3081 t
ORIGIN      
        1 ttatttttta actatgaacg tcagaccttt ttgttagttt gaaagtgttc ttatcttttt
       61 gctaatgacg cttaaatcgc tttgtcatct tgaccaagtg agcgctgaat agccttgaca
      121 agctcaacaa gcacaaccat caagagactt ccaacaataa caactagcca ttgtgtaagg
      181 gtcaaatgag tcacatgaaa gaatttgtta aagccaggga caacaactgt agccatcaag
      241 gcaacaaagg ctactgggat agaatagtta aataatttat tcttaaataa tccaactgta
      301 aagatagact gataaacgga cttaacatta taagcatgca ccagctgaat gagaccaagt
      361 gttacataag ccatcgttaa agcatcggca tgcacgtcat ggtagcttgt atgctctggg
      421 aacatcaagg caaagccata aacaccaagc actaggattg tctgaagggc accctgatac
      481 agaatagctt cttttacacc accgtcaaag aagcttgatt ggcgtccacg aggcttgtgc
      541 ttcatgacac caggctcagc aggctcaaca ccaagagcga tcgctggcag cgtatctgtt
      601 accagattaa tccaaagcag gtgaaccggc tgaagcacgt cccagccaaa taaggtagca
      661 agaaagatcg taaagacctc agccatgttg gcagaaagca ggtactgaat tgttttttga
      721 atgtttgaaa agaccttacg tccttcttca acggcaacaa taatagttgc aaagttatca
      781 tcggcaagga ccatatcaga agctccctta gaaacctctg tacctgtaat ccccatacca
      841 ataccaatat cagctgtttt aagagacggc gcatcattga caccatcacc agtcatagca
      901 acaaccttac cttcattttg ccaagcctta acgatacgaa ccttatgctc tggagataca
      961 cgcgcataaa cagaatattg tctaaagacc ttttggaagg cttcgtcaga cagctcattg
     1021 agctcagcac ccgtaaagac atggtcaaca ccatcttctt cgataatgcc aagacgcttg
     1081 gcaatagctt ccgctgtatc ctggtggtca ccagtaatca tgatcggacg aataccagcc
     1141 tccttagcca ccttaacagc ctgagccgct tcagggcgct ctgggtcaat catgccaaca
     1201 agccctgaga aaatcagctc tgcttcgacc acctctgttt caagtactgg aatcacttct
     1261 gtgtatttgt aagccatcat caagacacga agggcttgct tagccaagtc cttattagta
     1321 gccagaatcg tttgcttatc agcctctgta atcggacgaa tatctccatt ttcttcaatt
     1381 tgagtgacac gttttaacag ctggtcagga gcacccttaa cagcgatgaa gtatctgcca
     1441 tcagcttgct tgtgaatggt tgacatcagc ttacggtcag aatcaaatgg taattctgcc
     1501 acacgaggtt ctgaaacaag agcctcacgc acatcaaagc gatgatctaa gccaaattgc
     1561 accaaggcag tctctgtagg atcaccaatc agcttacctg ctggatcaac cttagtatca
     1621 ttggcaaaat tcatcacacg aagggtattg ttgtcaaagg caatatcagc tgatgactct
     1681 tgaagtgccc cgttagtata aaccttttca actgtcatct ggttcatggt caaggtacca
     1741 gttttatctg aggcgataat ttcagttgaa ccaagggttt cgaccgcagg caatttacgg
     1801 ataatagcgt tacgctttgc tagcacctgt gttccaagag aaagcacaac cgtaacaata
     1861 gctggaagcc cctctggaat ggcagcaacc gcaagcgcca ctgatgtcat caagccttca
     1921 agtgggcgct gaccacgtaa aaagacacca actgcaaagg tcacagctgc aatcacaaga
     1981 atagcatagg ttaaaatctt agatagattg tcaaggtttt gctttagcgg tgtgtctgtc
     2041 tcatcagcat tagccagcat gccagcgata tggcctacct cagtgtacat accggtgttt
     2101 gtgacaaccc ccataccgcg tccataggta acgtttgagt tttggtagcc catgttaaca
     2161 cgatcaccaa taccagcatc agcagaaacc tctcttgaca ggtccttttc aactggaact
     2221 gactcaccag taagagcagc ttcctcaatt tttaaggaat tgacctctaa caaacgcata
     2281 tcagctggca ccacatctcc tgcctctagc aggacaatgt cgccagggac aagctcttta
     2341 gagtcaacct caatcacatg accatcacga cgcacacgtg ctaagggact agacatggat
     2401 tttaaggcct caatcgctgc ctctgcctgc ccttcctgat aaaccccgaa ggctgcattt
     2461 aagataacaa cagctaaaat aatgatggca tctgtcaagc cctccatccc ttctgttacc
     2521 acagaaagaa aggccgctgc aaccaaaata ataatcatca aatccttaaa ctgatcaagg
     2581 aatttcatga acaggctgcg cttttcaccc tcgtcaagct cattacgccc ataagctgct
     2641 aggcgctgct gtgcctctgt actcgttagc cccttacgac tagactctaa ttgagctaat
     2701 actgtttctt cactttgcgt atagaacgct tcatgtcttt gttctttcga caaattggtc
     2761 cctccttggt ctttttatgc tttattcaac taaaaagacc tgtttatttt tcttaaacaa
     2821 gtctcgctgt ttcagattgt accggaaatc gaaattccgt attgacgaca caatcacggc
     2881 taaccgtctg ctactccctt gatatagtca ctattataat aaaatgatga ccaaaaaaca
     2941 agaaaaaaac aaggaaatat tttttaaaag ccccaaatca tctgatgatt ttcagagcaa
     3001 aggtaactga tgaccaagct tagactatca ttaccgagat acagacagca gacacaggct
     3061 gtcatcttag gagactaaca aaggacttcc tctgctgaga tcaataccac ttgatctcca
     3121 aatgataatg agcaaaggcc gtctcagtgc tgggctgtaa taaagcataa tctagggtca
     3181 ctgtctgctg gccatgatcc aagtgaaaat ggctcgtatc tgtcaaaaat tgctggatcc
     3241 ctacaggcgt cggaatagcg atcaaggctt ttttgttagc aagaaacctc atcacagact
     3301 gaggctttga aaagcgactc atcgttagct cagcagcatt gaacttaatc actacccttt
     3361 cgttgttatt attttgataa attagatagg tagcatctgc cttttgtctc aaatccccag
     3421 tatgaatctc cttgattagc tctgtttcct gaccatagct gatcttgtta ttaatttcaa
     3481 tcttcatgat atcttctttc tcttgagttt tgctcgtcta ttctaccaat ttctgaccat
     3541 tttcgcaatt tctgctataa tagaagcatg aatgaaaaag tatttcgtga ccctgttcac
     3601 aactatatcc acgttaatca tcagctcatt tacgagctaa tcaataccaa ggaatttcaa
     3661 cgactaaggc gaattaagca ggtgccaaca acagccttta cctttcatgg tgccgagcat
     3721 agccgctttt cacactgtct tggtgtctat gagattgctc gccgtgtcac agagattttt
     3781 gaagaaaagt atgcagacct ttggcataag gaggagagtc ttgtaaccat gactgctgcg
     3841 ctcctgcatg atattggcca tggtgcttac tcgcacacct ttgagaccct atttgatact
     3901 gatcacgaag ctgttactca agatatcatt accagtccag aaacggaaat taatgcgatt
     3961 ttgacgcgct actctcctga ttttcctgac aaggtagcta gtgttatcaa ccacacttac
     4021 cccaataaac aggtagtgca gctgatctct agtcaaatcg actgcgatcg catggattat
     4081 ctgctgcgcg actcttactt ttctgcggct aattatgggc aatttgacct aatgcgcatt
     4141 cttagggtta ttcgacctgt gaaagatggc atagcttttg atctcagcgg tatgcatgcc
     4201 gtagaggatt acattgtcag ccgctttcaa atgtatatgc aggtttattt tcaccctgcc
     4261 agtcgagccg tcgagctgat cctacaaaac ttgctgaagc gtgctaaggc tctctatcct
     4321 agccagcagg actatttcca aaagacagcc cctggtctca ttccattttt tgaaaaaagt
     4381 ttcacgcttg ctgattatct ttgcttagat gatggtgtgc tcaataccta tttccagcaa
     4441 tggattacta gtgaggacca tatcctgtca gacctgtcta gtcggtttat caatcgaaaa
     4501 attttaaaat ctgtcacctt tgaccaagaa tcacaacagg atttagagcg cttgcgaaag
     4561 cttgttgagt cagttggttt tgatcctgat tattatacag gtatccatgt caattttgac
     4621 cttccttatg atatttaccg tcctgagctg gaaaatccaa gaacccaaat tgaaatgatt
     4681 caaaaagatg gcagcagggc tgagctatcc cagctctctg cgattgtcaa agctctcaca
     4741 ggcacaagct atggtgatag acgcttttat ttcccaaagg aaatgttaga gcttgatgac
     4801 ctctttacat cagataagga agcctttatc agctatatct ctaacggaca ctttcatttt
     4861 aacaactaag gaccagccaa ggtccttttg gctttttcat cacgctctag atttaaaatg
     4921 gtatattacc cgataaggac agctagagct ctgacaagca caagccacca aacacagcag
     4981 agcctttaat attgccaaaa tctcttttgt tttcatgaca aaagaaccta tttttagtaa
     5041 gatagaaggt ggcaaatcat tgattacaaa tcagaacaac caaggagaat tccatgtcta
     5101 tcaaacttgt tgccattgat attgatggca ccttactcac tgacgatcga cgcgttacta
     5161 atgacgtttt tgatgccata caggaggcca aggcccaagg agtgcatatc gtcattgcta
     5221 cgggacgtcc cattactggg gtcatctcat tattagagca attgcaatta aatcaaaagg
     5281 gagatcatgt catcaccttc aatggtggac tgattcagga cactgcaacc ggtgaagagg
     5341 tggttaaaga gctgatgacc tacgatgatt acctcgacat agaatattta agccgcaggc
     5401 taggcgttca catgcatgcc atcacaacag agggcatcta tactgctaac cgaaatatcg
     5461 gcaaatacac tgtacgagaa gcaaggcttg tggacatgcc tgttttttat cgaacacctg
     5521 aggagatggc tgacaaagag atcgtcaaaa tgatgatgat tgatgagcca aaccttttag
     5581 atgaggccat caaacagatt cctcaagcct tctatgacac ctacaatatt gtcaaatcaa
     5641 caccttttta tctcgaatta acaccaaaaa ctgtcagcaa gggcactgct attggtcacc
     5701 ttgccaaaaa gcttggcatt gacatgtccc aaacgatggc aatcggcgat gctgaaaacg
     5761 atcgagccat gcttgaagcg gttgctaacc ctgttgtcat ggaaaatggg gctcccgagc
     5821 tgaaaaagct ggccaaatac atcaccaaat caaacaatga cagcggcgta gcgcatgcta
     5881 ttcggaagtg ggtattaaac taatgtatac atataaaatc ggaatttcag ctaaagagca
     5941 cgatcagttt gtcctatcac atcctcaggt caatctgctg caaagcgctc attgggctca
     6001 ggtaaaggat aactgggagc atgagctcat tggtttttac caggatgaca agcaagtcgc
     6061 tgctgctgct tgccttatca agagactccc cctaggcatg accatgattt acattcctcg
     6121 agggccgatt atggattatt ctgactttga gttggttaac ttcgtcatga ctagcctaaa
     6181 ggcttatggt aaatccaagc gagctctcat gattaaatac gatccttcct tgtttatcag
     6241 tcaggcctta ataggtgaag aaagaaagga caatgacttc accctctcca ttattgattt
     6301 tttaaagacc atcggtgttg aatggactgg caggaccaag gagcttgagc aaacgattca
     6361 gccccgcttt caggccaaca tttacgccaa ggactttaag ctccaaagct tatcaaaaaa
     6421 agccagacag tctatccgaa ctgctcaaaa taagggagtc gagattatta ttggctcaac
     6481 agagctactt gaagacttct cagcactgat gaaaaagact gaggagcgaa aacacatttc
     6541 tttgcgtggc atttcctatt atgacaaatt aatgaccact tacgctaatc aggcttacat
     6601 taccatggct agattgaacc ttcccaagca aaaagcgctc atacagcagc aattagagga
     6661 agccttgagc aatcagcagg cctttaccca gcacagtaag ccaggtaagg tcgcagaaaa
     6721 ccaaaatacc attaaaaggc ttgaaaagga attggctttt ctagataagg aaatacaagc
     6781 aggtaaaagc cttgtacctc tagcagctac cctgacactg atctatggac agacctctga
     6841 aaacctatac gcaggtatgg ataatgactt tcgccaatat caggcagccc tcttaacctg
     6901 gtatcatacc gcagaagagg cctttaagcg cggttgtcaa tggcacaatt tagggggcgt
     6961 tgaaaaccaa ttagatggtg ggctgtttca gtttaaagca agactaaacc cagctatcga
     7021 agaatttgca ggagaattca gcattccagt tggacctatc tcaaaggtgg ccatgatagc
     7081 ctacaatttg agaaaaaaac taaggagtaa cccttaatgg ctttagatat cattgacaaa
     7141 gaaacgtttg gctcattttg cagtcaaatg aagtataaat ccttcattca atctatagaa
     7201 atggcagagc tgctgcaaaa gcgtggttat cagacacaat accttgcaat cagtgaccag
     7261 aaaaacatta agattgcagc cattctctac agtataccaa tgaccggcgg cttacgcatg
     7321 gaaatcaact caggtccagt agtggctgat acgacctaca caacagcctt ttacaaagcc
     7381 ttacaggact atgccaagca gcagggagca cttgagctag tcatcaagcc ctacgatacc
     7441 tatcagacct ttaccagcga tggtcaccca aacgatgatg aaaagccaga gctgatcaag
     7501 accttgacag agctcaattt tacacatgat ggcctgctaa caggctacca taatggtgaa
     7561 ggagattggc attatgttaa agatttaagc ggattgacct ctgctaatgt catcaattcc
     7621 ttcagtaaaa agggcaaggc cctgctaaaa aaagccaaaa cctttggcat taagctacat
     7681 aagctcaatc gtgatgagct aacacaattc aaggaaatta ctgctgctac atctagtcga
     7741 agagattata ccgacaagtc tttatcttat tatcaggatt tctatgatag ctttggggat
     7801 agctgtgaat ttatggttgc aaccctcaat tttgatgact acctgaccaa tctagagcac
     7861 agtcaagaca agctaaagca gcgcattagc aaattagagg cagacctagt taaaaaacca
     7921 aaatcagaaa aaaaacaaaa tcaactacgg gaactctcca gccaatttga tacctttcaa
     7981 gttcggatag ctgaagcaca ggagttaatt gtcaagtatg gcaaaaagga cattcctcta
     8041 gctggtagtc tctttgttta caccccgcag gaggctgtct atctcttttc tggctcctat
     8101 ccagaattta acaggttcta cgcgccagcc ctattacagg aacatgtcat gctaagagcg
     8161 attgaaaaga aaatcagctg ctataatttt cttggtatca tgggcgaatt tgatggctct
     8221 gatggtgttt tacgctttaa gcaaaacttt aacggctata tcacacgaaa gatgggaacc
     8281 tttaggtatt atccaaagcc cttcaagtac aaagccatac aggccatcaa gacaatgctt
     8341 ggtcgcagct aagtcaagct agtggctaag cagcccttta agccttccaa tggctattga
     8401 ccacaataat aaatccttga ttgtcttact cagaacccct ttagtaaact ttccaaccta
     8461 aaaataaggt ataggtgatc ccatgctcaa gaaggctatc aagcaaacca aaagctcaag
     8521 gaattaaccc ttgagctttt tagctatatt ataattgtca ttagttgaca aaatcaagca
     8581 aggcaaggaa gctatctgct tctagtgatg caccaccgac aagagctccg tcaacatccg
     8641 gacaagccat gtactcctta atgttttcag gcttcacaga accaccatac tgtacacgaa
     8701 ccttgtctgc cacctcttga ccaaagtcag cagcaaccac atcgcgaaca gccttacaca
     8761 tgctttgagc atcttcttga gtggcagatt taccagtacc gatagcccag attggctcat
     8821 atgccaatac caatgaagca acctgctcag cagatagccc ctctagagcc gcagacacct
     8881 gtgcaccaac aaaggctact gccttgccag cctcataggt ctcaagagac tcaccgcagc
     8941 agataattgg tgttaagcca ttagcaaaga tggcttttgc ttttttatta atatcttcgt
     9001 ctgtttcgtg gaagtaatca cgacgctcag agtgaccaat caccacataa tcagctccca
     9061 tgtcagcaag aaccttagga gaggtttcgc ctgtataagc gcctgaattt tcaaaataac
     9121 agttttgcgc agcaacctta aggacagagt ccttagcagc ctcaattgta gtgaccaagt
     9181 caacagctgg tgctgctact gcaacgtcaa caagatcgtt tgaaggtaat ttgcttacta
     9241 ctgccttaac aaaggctttt gcctcttgag gatttttgtt cattttccag ttaccggcaa
     9301 taattggttt acgtgacatt tcacatacct cttctttttt tatttacatc tactattcta
     9361 gcacaatttc tatgctaata aaagaaaatg gctgactttt aggaatattt tcacaaagaa
     9421 aagagtattt tctgaaacca ttttcaaacg ataaggctta tcgattagct aagcagaccc
     9481 gctaagtcct catctttata aacagagcaa aaagagccct taaaacaagg gctctcacaa
     9541 ttaagctgtc tgactttaat cgttatctgg gaacttaatc aaaattaagc ttcgatttct
     9601 gaaacgatac ctgaaccaac agtacgtcca ccttcacgaa ttgagaatgt agtaccttgt
     9661 tctacggcga ttgggtggat caactcaacg tcaatagtca cgttatcacc aggcataacc
     9721 atttctgtac ctgctggaag ctcgattgaa cctgttacgt cagtagtacg gaagtagaat
     9781 tgtggacgat agttgttgaa gaatggtgtg tgacgtccac cttcttcttt agtaaggata
     9841 tatacttcac ctttaaattt agtgtgtggg ttgatagaac ctggcttagc aataacttga
     9901 ccacgttcga tttcatcacg ttgtacacca cgaagaagaa caccaacgtt gtcccctgca
     9961 agaccttcgt caagctgttt acggaacatt tcgacaccag taacaactgc ttttttgatc
    10021 tcgtctctga taccaacgat ttcgatttcg tcgttaacac gaacagtacc gcggtcgata
    10081 cgtcctgaag caacagtacc acgtccagtg attgagaata cgtcctcgac tggaagaagc
    10141 aatggcttgt ctgtgtcacg ttctggttct ggaatgtatg aatcaacagt atccatcaat
    10201 tccatgatga tatcttcgta tttgctgtcg ccttcaagag ccttaagcgc tgaaccttgg
    10261 ataactggaa ggtcatcacc tgggaaatca tattctgaaa gaaggtcacg aatttccatt
    10321 tcaacaagct caagcaattc ttcatcgtca acaaggtcaa ccttgttcat gaacacgata
    10381 aggtgcttaa caccaacctg acgtgaaaga aggatgtgct cacgagtttg tggcattggt
    10441 ccgtcagttg aagcaactac aaggatagct ccgtccattt gagcggcacc agtgatcatg
    10501 tttttaacgt agtccgcgtg tcctggtgcg tcgatgtgcg catagtgacg tgtagcagtt
    10561 tcgtactcaa cgtgtgcagt gttgatagtg attccgcgtt cgcgttcttc tggagcagca
    10621 tcgattgaag cgtagtcttt tggttggtta actgagcttg gtagacgacg tgcaagaaca
    10681 gttgtgattg cagctgttaa agtagtttta ccatggtcaa cgtgtccaat tgtaccaatg
    10741 ttaacgtggg gtttactacg atcgtatttt tcttttgcca ttttaggaaa agcctccaat
    10801 aaaatatatt ttatagatag acggtaggca atacagtcta actttacctt actattgtag
    10861 caaattataa ggaaattgca agcagtaagt gaggaacttt aacggattta tcgttatccc
    10921 tgatttcaac aaccctagca tacaaaaaag gaaagagttt tcgtcttctc ccaggcaatc
    10981 cgctctttac cgttttttgc ttttcaaggc tctaggcatt tgcatacttt tggaggagag
    11041 ttgaattgtt aagagataat gcattcggag atctataaat cataggcagg acataccgat
    11101 ccaaaactaa gatagtggag acttgatggt ccatgacaga cgcgcgaaac agctatttcc
    11161 gaatgataat atagatgaga gtagacactt tcaacgttct tcctatagta aaagctatgc
    11221 aaaatcctac atattcttga aatagctgaa cattgaaata caggaagctt tattttattg
    11281 ctaaaaatct ttcatgtg
//
LOCUS       DARYYD010000060        10996 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.061, whole genome shotgun sequence.
ACCESSION   DARYYD010000060 DARYYD010000000
VERSION     DARYYD010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10996
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.061"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(32..1213)
                     /locus_tag="TV188_001635"
     CDS             complement(32..1213)
                     /locus_tag="TV188_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1534967.1"
                     /translation="MTKRLLLFVLVCLCFLGISQVHAEDVMEITRKAGYTVSEVNRPK
                     ASIVVDAKTSEILWQDNIDMPRDPASMSKMFTLYILFEELAKGKVTLDTTITATETDQ
                     AISKIYEISNNNIVAGVAYPIRDLIIMTVVPSSNAATVMIANYLSNNDASAFIDRINK
                     TAKELGMTNTHFSNASGAIAQAFQGYYLPEKYDLTASNITTARDFATLIYYFLTNYPS
                     ILDFTNQTVVRTMVGTPYEEEFHSYNHSLPDGKFGIEGVDGMKTGSSPSAAFNAVVTA
                     KRGNTRLITVVLGVGDWSDQNGEFYRHPFINALTEKAFKDSKTLTKAKRSKLKRLAAK
                     PASTAAAAKKQLPQATTDQSFLEKIEQFVDDHRPLVLICLAIFILIVLLLALMAFMMG
                     R"
     gene            complement(1297..2532)
                     /locus_tag="TV188_001636"
     CDS             complement(1297..2532)
                     /locus_tag="TV188_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012680094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1534968.1"
                     /translation="MKKLIVTLAALMCLITNTSFAENFSVNSRQAIAVEMTTGKILYA
                     KEAQQKAPIASLTKLLTVYLVLKEIKAGRLQWDSQVTLSEYALQLATDPDISNPAFEQ
                     RPYTIKELVESSLIISANSSAVALAEHIAGSEPTFVDMMKKQLEAWGIRDYLLVNASG
                     LNNSMLKGHLYPGSQPDDENQMTARDLALIAQQLIQDFPELLTISSQPQLKWGEKALP
                     SSNLLLAGREMGRAGVDGLKTGTTSQAGQTMIATAVQDNMRVISVILHADQSDTDERA
                     RFVETNRLLDYCFNSYALEKLVAQNQVLPERLIVKQAAKQRLRVKASQTLTVVRPKDQ
                     TELSYSLRIKDKALKAPIRQNKKVGTLIYQDPKLIDSGYLAAPPAVAIVSAKSIPEKG
                     KLSKLFDFFQKVIGILINP"
     gene            complement(2854..4092)
                     /locus_tag="TV188_001637"
     CDS             complement(2854..4092)
                     /locus_tag="TV188_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEL1534969.1"
                     /translation="MKKVLIALTILAISCLAYPAQADHYDISAKHAIAVELDSGKILY
                     EKDADKTVSVASLSKVLTAYLVYKEVQAGKLKWDSSVTISNYPYKLTTNYTISNVPLD
                     ARKYTVKELLKALIVTNANSPAIALAEKIGGTEAKFVDKMIAQLKDWGITGAKVVNAS
                     GLPNHILGEHIYPGSSLDDDNQFSAADLALVTSHLLKEFPEVLKLSSQVQAEFNHQQI
                     FSYNYMLKGMPNYRDGVDGLFVSYSEKGGSSFLATSVENNMRIITVVLNADHAQDNDT
                     AVFTATNQLLQYVLTHFKKVVVLEKGKPDQLKALPVLDSPQKKIQLVPKKKLTMIKAL
                     DDKSKTTFQVSDTKNPLVAPIQKGQTLAKATLNDHSLIGKGYLGQAPSVELVAQKKVP
                     KSFFLKVWWNHFVRYVNQYL"
     gene            4400..6376
                     /locus_tag="TV188_001638"
     CDS             4400..6376
                     /locus_tag="TV188_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003102586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEL1534970.1"
                     /translation="MKKSKWLATLGVAALSVSILAACGNSSSKSSESKIYSYVYSSDP
                     STLDYISTSKATTNDITTNAVDGLLENDQYGNLIPSLAKDWKVSKDGLTYTYTLRDGI
                     KWYTSDGEEYADVTAEDFVAGVKHAADVNSDALYIIQDSIKGLSDYLNGKTKDFSTVG
                     VKALDKKTVQYTLNQPESFWNSKLTYSVLAPVNADFLKSKGKDFGKATDPSSILYNGP
                     FLITALTSKSSIELVKNENYWDAKNVHLDGVQLTFYDGQDQESLFRNFDDGAYSAARL
                     FPTTPSYKTVKKKYGDSITYGQQNATLYYAAFNLNRTSYNHTKKTSDSQKSDTQKAIL
                     NKDFRQAMTFAFDRIAYQAQSAGEDAANKSLRSTLVPPTFVKIGDKNFGDVVEEHLVT
                     YGSQWENVNLDDAQDGLYNPEKAKASFEKAKAALQAEGVQFPIHLDYPMDQTATVLLQ
                     QARSMKQSIEKTLGTDNVVIDIIELQKDVYENISYLAETPAQNDWDISTASGWGPDYV
                     DPSSYLDIFNPTLANSQTKSIGLEPGKDLAIASAAGLDEFTKLVTEAGKITDDLNARY
                     TLYAKAQAALTDSAIYIPTISLGGTPRVTKVVPFSGAFAWAGTKNDFYYKYVKLQDKP
                     VTAKQYDKALAEWKKEKKKSNEKYNNSLEKHIEK"
     gene            6440..7939
                     /locus_tag="TV188_001639"
     CDS             6440..7939
                     /locus_tag="TV188_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1534971.1"
                     /translation="MKKYIFERILRSLVSILLVTALTYTIVFTLVPKSLIFKQDPNYN
                     KMVTTPDKKTNYLNTVFENMGYISYYSSKELQNKASKLDPSVTTAPTKANEKIYQKYI
                     ASVGNGWKLGRFTESKGFYAVREIPIYERVWNFFSHLVVIDHPWKIKDPKNPNLERYV
                     RPEIDPAVGPALVGSGTKHKYLIYFNKQFPFIHQNIVTFDLGVSYPTYANIPVVQVIT
                     QGQGRTLQKEVTFPTGKTKLSSIDIYSRTYKTPSSLDSKDIANFGKGDAYTNTQNNYA
                     EPSMIANSFKIGIVGVLLSYLFGLPIGMLMAYYKNGWFDRFSTAATTFMLALPSIALI
                     YIVRFVGSYLGLPDTFPLLGAGDVRSYVLPALILGILGTPSTVVWFRRYIVDLQGSDF
                     VRFARAKGLSEFEISKNHLFKQAMVPIVNGIPQAIVGTIAGATLTETVFAFPGMGKML
                     IDSIKAANNSMVVGLVFIFAVLSILALLVGDILMTILDPRIKLSGKGGK"
     gene            7939..8865
                     /locus_tag="TV188_001640"
     CDS             7939..8865
                     /locus_tag="TV188_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1534972.1"
                     /translation="MAAIDKNKFTFVELDSYASEVIDAPAYSYWKSVFRQFFSRKSTI
                     LMLVILIAIILMSFIYPMFANYDFGNVSNINDFSKRYIAPNAEYWFGTDQNGQSLFDG
                     VWYGARNSILISVIATIINMIIGVIVGGIWGVSKAVDKVMIEVYNIISNLPQMLIIIV
                     LTYSIGAGFWNLIFAFCVTGWIGIAYSIRVQILRYRDLEYNLASQTLGTPTHKIVIKN
                     LLPQLVSVIVSMVSLLLPSYISSEAFLSFFGLGLPITEPSLGRLISNYSNNLTTNAYL
                     FWIPLTTLILVSLPLYIVGQNLADASDPRTHR"
     gene            8874..9944
                     /locus_tag="TV188_001641"
     CDS             8874..9944
                     /locus_tag="TV188_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534973.1"
                     /translation="MTEKQEIILSAKNIVVEFDVRDRVLTAIRDVSLDLYKGEVLAVV
                     GESGSGKSVLTKTFTGMLEANGRVASGTITYAGQELTELKNHKDWEAIRGSKIATIFQ
                     DPMTSLDPIQTIGSQITEVIVKHQKKSRSEAKALAIDYMTRVGIPEPEKRFGEYPFQY
                     SGGMRQRIVIAIALACKPDILICDEPTTALDVTIQAQIIDLLKTLQKEYHFTIIFITH
                     DLGVVASIADKVAVMYAGEIIEYGKVEEIFYDPRHPYTWSLLSSLPQLADEKGVLFSI
                     PGAPPSLYKPIVGDAFAPRSQYAMAIDFEETVPRFTISDTHWAKTWLLHPDAPKVQKP
                     AVIQDLHQKILKKMSRQEEGNV"
     gene            9937..10860
                     /locus_tag="TV188_001642"
     CDS             9937..10860
                     /locus_tag="TV188_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534974.1"
                     /translation="MSEKLVEVKDLEISFGEGKKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNETSSGEIRYDGKIINGKKSKSEANELIRKIQMIFQDPAASLNE
                     RATVDYIISEGLYNFNLFKTEDERKEKIKQMMSEVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMDPEFVIADEPISALDVSVRAQVLNLLKKIQSEKGLTYLFIAHDLSVVRFIS
                     DRIAVIHKGVIVEVAETEELFVNPVHPYTKSLLSAVPIPDPILERQKKLVVYHPEQHD
                     YSVDKPSMVEIKPNHFVWANQVEAERYRKEL"
BASE COUNT         3259 a         2144 c         2282 g         3311 t
ORIGIN      
        1 taccaagaag tctttttaat cagcaatgag cttaacgtcc catcataaag gccatcagag
       61 caagtagtaa aacaataagg ataaaaatgg ctaagcaaat caagacaagg ggacgatgat
      121 catcgacaaa ttgttctatt ttttcaagaa atgattgatc agttgtggct tgtggcaact
      181 gctttttggc agctgctgct gtgctggctg gtttagcagc aagcctttta agcttgcttc
      241 gttttgcttt ggtgagtgtt ttactatctt taaaggcttt ttcagtcaaa gcattaatga
      301 atgggtgacg gtaaaattct ccattttggt cagaccaatc accaactcct aggacaactg
      361 taatcagtct ggtatttcct cgttttgctg ttacgaccgc attgaaagca gcacttgggc
      421 tggatcctgt tttcatacca tcaacaccct ctattccaaa cttaccatca ggcagagagt
      481 ggttgtagga atggaactct tcctcataag gggttccaac catggtgcgg acgacagttt
      541 gattggtaaa atcaagaata ctaggataat tggtcaaaaa ataataaatt aaggttgcaa
      601 aatcacgtgc tgttgtgata ttagaagctg ttaaatcata tttttctggg agatagtagc
      661 cttgaaaggc ttgtgcgatt gctccgctag catttgaaaa atgcgtatta gtcatgccga
      721 gctctttggc tgttttgttg atccgatcaa taaaggctga cgcatcgttg ttggataggt
      781 agttggcaat catcactgtt gcagcatttg atgacggaac cactgtcata atgattaaat
      841 cacgaatagg gtacgcaact cctgcaacaa tattattatt gctgatttcg taaattttac
      901 taatcgcctg atcagtctct gttgctgtaa tggtggtatc aagtgttacc tttcctttgg
      961 ccaattcctc aaagaggata taaagcgtaa acatctttga catactagca gggtctctag
     1021 gcatgtcaat gttatcctgc cataagatct ctgaggtctt tgcgtcaaca acaatggagg
     1081 cttttggcct attaacctca ctaacggtat agccagcctt gcgggtaatt tccatgacat
     1141 cttcggcgtg aacctgagaa atgcctagaa agcacaggca caccaaaacg aatagtagca
     1201 atcttttagt caattcaaag ctccttaatg taaaaaaata atgtaagctt attatatcat
     1261 ttcaataata caaatgaaat atattttttg aaaatattaa gggttaatga gaatgccaat
     1321 gactttttga aaaaagtcaa ataatttgct aagtttccct ttttcaggaa tgcttttagc
     1381 tgagacaata gcaacagctg gcggtgctgc tagatagcca ctgtcaatga gcttaggatc
     1441 ctgatagata agggtaccga cctttttatt ttgacgaatt ggggccttga gtgctttgtc
     1501 tttgattcgt agcgagtaag acagctctgt ctggtcctta ggccgaacaa ccgttaaggt
     1561 ttgactagcc ttgaccctta gcctttgctt tgctgcttgt ttaacaatca gtctttcagg
     1621 caaaacttgg ttttgagcaa caagcttttc caaggcatag ctattaaagc aataatcaag
     1681 caggcgattg gtctcaacaa agcgagctcg ctcatcagtg tcagattgat cagcatggag
     1741 aatgacagaa ataactcgca tattatcctg cacagctgtt gcaatcattg tttgtccggc
     1801 ttggctggta gtgcctgttt taaggccatc aaccccagct ctgcccatct cgcgaccggc
     1861 taatagtaga ttagaactag gcaaggcctt ttcaccccat ttcaattggg gctgtgagga
     1921 gatggtgaga agctcaggaa agtcttgaat caactgctgt gcaatcagtg ccagatctct
     1981 agctgtcatc tgattttcat catctggctg tgagcctgga tatagatgcc cctttagcat
     2041 actgttgttt agccctgaag cattgacaag aagatagtct ctaatccccc aagcctccag
     2101 ctgttttttc atcatgtcta caaatgtagg ctctgagcca gcgatatgct ctgctagagc
     2161 tacagcagag ctattagcac taataatcag gctagattca acaagctctt tgatagtgta
     2221 aggtctttgc tcaaatgctg ggttgctgat atcaggatca gtggctaatt gcagagcata
     2281 ttcagatagg gttacctgac tatcccactg gagccgtcct gccttaattt ccttcaggac
     2341 taggtagacg gttagtagct ttgttagaga agcaatgggc gccttttgct gggcctcttt
     2401 ggcatatagg atttttccag ttgtcatttc aaccgcaatg gcttgacgac tattaacaga
     2461 gaagttctca gcaaaggaag tatttgtgat cagacacatg agcgcagcaa gtgtcacaat
     2521 aagttttttc ataccatcat tgtagcaagg aaatagtgat cggtcaaaag gtcattgagt
     2581 acctttaaag aaggctaagt caagactctg agtgagatga cgtccccaaa aatcaagcct
     2641 caaaaaaacc gtctgacatc aacagactaa agctgtcaat tcatacggtt ttgctgtttg
     2701 cagagctttt gtaggcctta gagcttgcta ggagctcttt tagctacctt cttggagagc
     2761 ttgacacaat ggtcaatttt tgcgagataa gcctaatgaa gccctgagtg aggccttggc
     2821 actaatgagg acataaggca taaaagctag tcattagaga tattggttaa cataacgaac
     2881 aaaatgattc caccagacct ttaaaaagaa gctttttggc accttttttt gagccaccag
     2941 ctcaacgctt ggcgcttgac ctagatagcc ttttccgatt aagctatgat cattaagtgt
     3001 ggcctttgcg agtgtttgtc ctttttggat aggcgctact aagggatttt tggtatcgct
     3061 tacttgaaaa gtcgttttgg acttgtcgtc aagcgctttt atcatagtga gcttcttttt
     3121 tggcactagc tggatcttct tttgaggact atctaaaaca ggaagcgctt taagctgatc
     3181 tggtttaccc ttttcaagga caacaacctt tttaaaatgc gtcaaaacat actgcagcaa
     3241 ttggtttgtc gctgtaaaga cggccgtatc gttgtcctgg gcatggtcag cattgaggac
     3301 aactgtaata atacgcatat tgttttcgac actagtggct aaaaaagaag agcctccctt
     3361 ttcagaatag ctaacaaaaa gcccatcaac accatcacga tagttaggca ttccctttag
     3421 catatagttg tatgaaaaaa tctgttgatg attaaactca gcttgaacct gacttgatag
     3481 ctttaaaacc tcaggaaatt cctttaaaag atggctagtg acaagagcaa gatcggctgc
     3541 actaaattga ttatcatcat caagactaga tcccggatag atatgctctc ctagtatgtg
     3601 gttaggcagg ccactagcat tgacgacctt ggcacctgta atgccccagt ctttcaattg
     3661 agcgatcatt ttatcaacaa acttagcctc tgttcccccg attttttctg ccagggcaat
     3721 agcagggcta ttagcattgg tgacaataag agcctttaac agctctttaa cagtatattt
     3781 tctagcatct aagggcacat tgcttatggt gtagttggtg gttagtttgt aagggtagtt
     3841 agagatcgtt acggagctat cccattttaa ctttcctgct tgcacctctt tgtacaccaa
     3901 ataagctgtt aaaaccttgc ttagagaagc cacagaaaca gtcttgtcgg cgtccttttc
     3961 gtatagaatc ttaccgctat caagctcaac agcaatcgca tgcttggcgc taatatcata
     4021 atgatcagcc tgtgctggat aggccagaca agatatggct aatatggtca aagctattaa
     4081 aacctttttc atttgaataa tccttctagt cgttttttta attataccat aatttttcaa
     4141 gaagcttgac taaacctctc agagaagaga gatcattatg agaaaatgct agctgttatg
     4201 atagcgataa cgaactgtat aaaaatagca aataatgtat cttaaacgtc atcagatcgt
     4261 caacagaaaa aatcttgcaa aatattcaga taattttgcg atcgctattt ccatcagcta
     4321 aaatttgtgg tataatagct ccaattaacc aatttcattt atgctgataa atgaaaaata
     4381 acgtttaggg gtgacttcta tgaagaaaag taaatggttg gcaacgctgg gtgtcgcagc
     4441 gctgtcggtg tccatcctgg cagcctgtgg aaacagctca agtaaaagca gtgaatcaaa
     4501 gatttatagc tatgtctatt ctagtgatcc aagtacttta gactatatca gtacaagtaa
     4561 agcaacaaca aatgacataa caacaaatgc tgttgatggg cttttggaaa atgaccaata
     4621 tgggaattta atcccctctc ttgctaagga ttggaaggtc tcaaaggacg gcttgaccta
     4681 tacctacacg cttcgtgatg ggattaagtg gtacacatct gatggagaag agtatgcaga
     4741 tgtgacagct gaggattttg tagctggagt aaagcacgca gcagatgtta actctgatgc
     4801 cctatatatc attcaggact ctattaaagg cttaagcgat tacttgaacg gtaagaccaa
     4861 ggacttttca accgtaggtg tcaaagcgct tgacaaaaaa acagttcagt acacccttaa
     4921 tcaaccagaa agcttctgga attcaaagct aacctatagt gtcctagctc cggtaaatgc
     4981 tgacttctta aaatcaaagg gcaaggattt tggtaaggca acagatccat catctatcct
     5041 gtataatggt ccatttctta tcacagcttt gacaagcaaa tcctctatcg agcttgtcaa
     5101 aaacgaaaat tattgggacg ctaagaatgt tcaccttgat ggtgttcaat tgacctttta
     5161 cgatggacag gatcaggagt cattgtttag aaactttgat gacggtgctt actcagcagc
     5221 gagattattc ccaacaacac cttcttataa aactgttaag aaaaaatatg gagacagtat
     5281 cacttacgga caacaaaatg ctactctcta ctatgcggcg tttaacctaa atcgtacgtc
     5341 ttacaaccac actaagaaga cctcagatag ccaaaaatca gatacccaaa aggctatctt
     5401 aaacaaggat ttccgtcagg ctatgacatt tgcctttgat agaattgctt atcaggcgca
     5461 atcagcaggt gaagatgcag ctaacaaatc gcttcgtagc acacttgtgc caccgacatt
     5521 tgtgaaaatt ggcgacaaaa actttggtga tgttgttgag gagcacttgg tgacctatgg
     5581 tagccagtgg gaaaatgtaa atctagatga tgcacaggat ggcttgtaca atcctgaaaa
     5641 ggcaaaagca tcatttgaaa aagcaaaagc agccctacaa gctgagggtg tacagttccc
     5701 aatccatctt gattacccaa tggatcaaac tgcaacggtg ctcttacagc aggctcgctc
     5761 tatgaagcag tcaattgaga aaacattagg aactgacaat gttgtgattg atattattga
     5821 gcttcagaaa gatgtttatg aaaatattag ttatctcgcc gaaactcctg ctcaaaatga
     5881 ctgggatatt tcaacggctt ctggctgggg acctgattat gtcgacccat cgtcatatct
     5941 tgatattttc aacccaacgc ttgcaaactc acaaacaaaa tcaattggac ttgagccagg
     6001 taaggatttg gccattgcta gtgcagctgg cttagacgaa tttacaaagc tagtgacaga
     6061 ggcaggcaag attactgatg atctcaacgc ccgctacacg ctctatgcta aggctcaagc
     6121 ggcattgaca gactctgcta tttacatccc gactatttca cttggtggaa caccacgtgt
     6181 aactaaagtg gtaccgtttt caggcgcctt tgcttgggct ggtactaaaa atgactttta
     6241 ttacaaatac gtcaagctac aagataagcc tgtaactgct aaacaatatg acaaagcatt
     6301 agccgagtgg aaaaaagaaa agaaaaaatc taacgaaaaa tataataatt ccctcgagaa
     6361 gcatattgaa aaataaattg atgttcatta agaactttct cttagaggag gaagttcttt
     6421 tgaactgctg gggactagaa tgaaaaaata catatttgaa cgcatattga ggtcgcttgt
     6481 ttcaatcctg ctggtaaccg cactaaccta tactattgtc tttaccttag tgccaaaaag
     6541 cttgattttt aagcaagacc ctaattacaa taaaatggtg acaacacctg ataagaaaac
     6601 caattatcta aatactgttt ttgaaaatat gggctatatt tcctattaca gcagtaaaga
     6661 actgcagaat aaggcttcaa agcttgatcc ttctgtaaca actgcaccaa ccaaggccaa
     6721 tgaaaaaata tatcaaaaat atattgcttc tgtcggtaat ggttggaagc ttgggcgctt
     6781 tacagaaagt aagggatttt atgccgttag agagattcca atctatgagc gcgtgtggaa
     6841 tttctttagc catttggttg tgattgatca cccatggaaa atcaaggatc caaaaaatcc
     6901 aaatctagag cgttatgtgc gaccagaaat tgaccctgct gttggtccag ccttagttgg
     6961 ctctggtact aagcacaaat acttgattta cttcaacaag caatttccat ttatccatca
     7021 aaatatcgta acctttgatt tgggagtgtc ctatccaacc tatgccaata ttccagttgt
     7081 tcaggttatc actcaaggac aaggaagaac acttcaaaaa gaggtcacct tcccaacagg
     7141 caaaacaaag ctgtcttcaa tcgatattta ctctcgaacc tataaaacac caagctcttt
     7201 agatagcaag gatattgcca attttggtaa gggtgatgct tataccaata cacaaaataa
     7261 ctatgcagag ccatctatga ttgcaaattc ctttaagatt ggtattgtcg gtgtcttgtt
     7321 gtcctatctt tttggtttgc caattggtat gctgatggct tattataaga atggctggtt
     7381 tgaccgcttt tcaacggctg ccacaacctt tatgttagcc ctgccaagca ttgcgcttat
     7441 ctatattgtt cgatttgtcg gttcttattt gggcttgcca gatacctttc cgctgctagg
     7501 agcaggagat gttaggtctt atgtgctgcc tgctcttata ttaggaattc ttggtacacc
     7561 aagtacagta gtttggttcc gacgctatat tgtggacttg caaggcagtg attttgttcg
     7621 ctttgcacga gcaaaggggc tttcagaatt tgagatttca aaaaatcatc tctttaagca
     7681 ggctatggtg cctattgtta acggtattcc acaagccatt gtcggaacaa ttgccggtgc
     7741 aaccttgaca gaaaccgtct ttgctttccc aggaatgggt aaaatgctga ttgattccat
     7801 aaaagctgct aataactcta tggttgttgg tcttgtcttt atttttgctg ttttatcaat
     7861 attagccttg ctagtaggtg atattcttat gacaatttta gatccacgta ttaaattatc
     7921 aggtaaagga ggtaagtaat ggcagcaatt gacaaaaata aattcacctt tgttgaatta
     7981 gatagctatg catcagaagt cattgatgcc cctgcttact cttattggaa atctgtattt
     8041 agacaatttt tctcacgtaa atcaactatt ttgatgctgg ttattttgat tgctattatt
     8101 ttgatgagct tcatctaccc tatgtttgcc aactatgact ttggtaacgt gagcaatatt
     8161 aatgattttt caaaacgtta tatagcacct aatgcagagt attggtttgg tacggatcaa
     8221 aatggtcaat cgctctttga tggcgtttgg tatggtgcta gaaattcaat cttaatttca
     8281 gttattgcaa ccatcatcaa tatgattatc ggagtcattg tcggtggtat ttggggtgtt
     8341 tccaaagcag ttgataaggt aatgattgag gtgtataata tcatctctaa cctgccgcaa
     8401 atgctcatta tcattgtgtt gacttattct atcggagcag gcttttggaa cttgattttt
     8461 gctttttgtg tgacaggctg gattgggatt gcttattcga ttcgtgtaca aattttgcgt
     8521 tatcgtgatt tagaatacaa tttagcaagt cagaccttag gaacacccac ccataaaatt
     8581 gtcattaaaa atcttttacc tcaattggtt tcggtgatcg tttcgatggt ttccttgcta
     8641 ttgccgtcct atatttcatc agaggccttc ttatccttct ttggcttggg attaccaatc
     8701 acagaaccaa gcttgggtcg attgatttca aattattcaa acaatttaac aacaaatgcc
     8761 tatttattct ggattccatt gacaactctt attcttgttt ccctaccttt atacattgta
     8821 ggacaaaact tagcagatgc tagtgatcca aggacgcata gataggagaa gtcatgactg
     8881 aaaaacaaga aattatatta agtgctaaaa atattgttgt agagtttgat gtgcgtgatc
     8941 gtgtactgac cgctattcgt gatgtttctc ttgatttgta taagggagag gtattggctg
     9001 ttgttggtga gtcaggctct ggcaagtctg ttttaactaa gacatttaca ggaatgctgg
     9061 aggcaaatgg acgtgttgct tcagggacga taacctatgc aggtcaagaa ctaacagagc
     9121 ttaaaaatca taaggactgg gaagctattc gcggctctaa aattgccact atctttcagg
     9181 acccaatgac tagtctagat ccgattcaaa cgattggcag ccagattact gaggttattg
     9241 ttaagcatca gaaaaaatct agatcagagg ctaaggcttt agcaatcgac tatatgacaa
     9301 gggtcggtat tcctgagcca gaaaagcgtt ttggagagta tcctttccaa tattctggcg
     9361 gtatgagaca gcgtattgtt attgccattg ccctagcttg taagccagat attctgatct
     9421 gtgatgagcc gacaacagct cttgacgtta ccatccaggc tcagattatt gacctattaa
     9481 agacgcttca aaaagagtat cacttcacca ttatctttat cacgcatgac ctaggagtgg
     9541 ttgcaagtat tgctgataag gttgctgtta tgtacgcagg ggagattatt gaatacggaa
     9601 aggttgagga aatcttctat gatcctcgtc acccctacac atggagctta ttatctagcc
     9661 taccgcaatt ggcagatgaa aagggcgttc tgttttcaat tccaggggca cctccgtccc
     9721 tatacaagcc aattgttggt gatgcctttg cgccacgctc tcagtatgct atggccattg
     9781 attttgaaga aacagttcct cgttttacga tcagtgacac gcactgggca aaaacctggc
     9841 tcctacaccc agatgctcct aaggttcaaa aaccagctgt tattcaggat ttacaccaaa
     9901 aaatattgaa aaaaatgtca cgccaggagg aaggaaatgt ctgaaaaatt agttgaagta
     9961 aaagacctgg agatttcctt tggagaggga aagaaaaagt ttgttgccgt taaaaatgcc
    10021 aatttcttta tcaataaagg agaaaccttt tctcttgttg gagaatcagg cagtggaaag
    10081 acaacaatcg gtcgtgccat cattggttta aatgagacaa gttcaggcga aatccgctat
    10141 gatggtaaga ttattaatgg taaaaaatca aaatctgaag ctaatgaact gattagaaaa
    10201 atccaaatga tttttcagga tccagcagcc agcctgaatg agcgtgcaac ggttgattat
    10261 atcatctcag aaggccttta taattttaac ctattcaaga cagaagatga acgtaaagaa
    10321 aaaattaaac agatgatgtc agaggtgggc ttgcttgcag agcacctgac acgctaccct
    10381 catgagtttt caggtgggca gcgtcagcgt ataggcattg caagagcgct tgtaatggat
    10441 ccggagtttg ttattgctga tgagccgatt tcagctcttg atgtatctgt tcgtgcccaa
    10501 gtcttgaatc tgttgaagaa aatacagtct gaaaaaggct tgacctattt attcattgct
    10561 catgatttat cggttgtgcg ttttatttca gatcgtattg ctgttattca caaaggagta
    10621 attgttgaag tcgccgaaac agaagagctt tttgttaacc ctgttcaccc ttataccaaa
    10681 tctctgctgt cagcagtacc aattccagat cccattttag agcgtcaaaa gaaattggtg
    10741 gtttatcatc cagagcagca tgactattct gttgacaagc catcaatggt ggaaatcaaa
    10801 ccaaatcact tcgtctgggc taaccaggtg gaagcggagc gttaccgcaa agagctttaa
    10861 gattagttat catcacataa cagaatttag cctcagctag attctgtttt tgccttcctt
    10921 gggtagtctt ttttgttctg acaaggatag aaatatccag cattttccat ctatttacaa
    10981 aaaacctgtc aaaacc
//
LOCUS       DARYYD010000061        10712 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.062, whole genome shotgun sequence.
ACCESSION   DARYYD010000061 DARYYD010000000
VERSION     DARYYD010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10712
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.062"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(885..1901)
                     /gene="adhP"
                     /locus_tag="TV188_001643"
     CDS             complement(885..1901)
                     /gene="adhP"
                     /locus_tag="TV188_001643"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEL1534975.1"
                     /translation="MKAVVVNQTSSGVEVVEHDVPSIGHGEALVKVEYCGVCHTDLHV
                     AHGDFGQVPGRILGHEGIGIVEKLGEGVTSLKVGDRVSIAWFFEGCGHCEYCTTGRET
                     LCRSVKNAGYSVDGGMSEYAVVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAGA
                     APGQWIVIFGAGGLGNLAVQYAKKVFNAHVVAVDINNDKLELAKEVGADIVVNGKEIE
                     DVAGYIQEKTGGAHGVVVTAVSKVAFNQAIDSVRAGGTVVAVGLPSEYMELSIVKTVL
                     DGIKVVGSLVGTRKDLEEAFAFGAEGLVVPVVEKVPVETAPEVFDEMERGLIQGRKVL
                     DFTL"
     gene            complement(2104..3156)
                     /locus_tag="TV188_001644"
     CDS             complement(2104..3156)
                     /locus_tag="TV188_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEL1534976.1"
                     /translation="MKAATYVAPGQLELIDQPKPEILAPTDAVVRLLKTTICGTDLHI
                     LGGDVPETTHGTILGHEGIGIVESVGSAVNNFKVGDKVIISCITACNTCYYCKKGIPA
                     HCESGGWILGHLINGTQAEYVHIPQADGSLYHAPKTVEDDALVMLSDIFPTSYEIGVQ
                     SAKVKPGDTVCIVGAGPIGLAALLTAQFYSPAKLIMVDLSESRLEAAKRFGATDTICS
                     GDLDDIVKKVHELTDGRGVDVAIECVGYPATFDICQKIIAIGGHVSNVGVHGKPVSLD
                     LQDLWIKNITMSTGLVNANTTEMLLNVLKSGKIDATKMVTHHFKLSEVEKAYEVFKNA
                     GSNNALKVIIENDITA"
     gene            complement(3651..6293)
                     /gene="adhE"
                     /locus_tag="TV188_001645"
                     /gene_synonym="adhC"
     CDS             complement(3651..6293)
                     /gene="adhE"
                     /locus_tag="TV188_001645"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEL1534977.1"
                     /translation="MTEKNSTVETTSVAATIDALVQKGLVALDKMRQLTQEQVDYIVA
                     KASVAALDAHGELAKHAYEETGRGVFEDKATKNLFACEHVVNNMRHQKTVGIIEEDDV
                     TGLTLIAEPVGVICGITPTTNPTSTAIFKSLISLKTRNPIIFAFHPSAQESSAHAARI
                     VRDAAIAAGAPEDCVQWIETPSLEATNALMNHDGIATILATGGNAMVKAAYSCGKPAL
                     GVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVSEFKS
                     YHTYFVNKKEKALLEEFCFGAKANSKNCAGAKLNPNIVGKPAAWIAEQAGFTVPEGTN
                     ILAAECKEVSENEPLTREKLSPVIAVLKAESRTDGVEKARQMVEFNGLGHSAAIHTAD
                     ADLAKEFGTKIRAIRVIWNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVSAVN
                     LLNIKKVGRRRNNMQWFKVPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGFLDR
                     IIEQLDLRRNKVVYQIFADVEPDPDITTVMKGTELMRTFKPDTIIALGGGSPMDAAKV
                     MWLFYEQPEVDFHDLVQKFMDIRKRAFKFPELGKKTKFVAIPTTSGTGSEVTPFAVIS
                     DKANNRKYPIADYSLTPTVAIVDPALVLTVPGFIAADTGMDVLTHATEAYVSQMANDF
                     TDGLALQAIKIVFENLEKSVKEADFESREKMHNASTMAGMAFANAFLGISHSMAHKIG
                     AQFHTVHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIAKLLGLPASTP
                     EEGVESYAKAVYDLGCRLGIKMNFRDQGIDEEEWKAHTRELAYLAYEDQCSPANPRLP
                     MVEHMEEIMNDAYYGYAERPGRRK"
     gene            complement(6713..8494)
                     /locus_tag="TV188_001646"
     CDS             complement(6713..8494)
                     /locus_tag="TV188_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010921782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEL1534978.1"
                     /translation="MRIKWFSFIRVTGLLLVLLYHFFKHTFSGGFVGVDIFFTFSGYL
                     ITALLIDEYVSKQTIDVVAFFRRRFYRIVPPLVLLILLTIPFTFLVKSDFIAGIGQQI
                     AAALGFTTNSYELLTGSSYESQFIPHLFVHTWSLAIEVHFYLLWGLLVWLLAKKGYSQ
                     KKFRGILFLISSAVFTLSYFSMFIRAFFVSDFSSVYFSTLSHSFPFFLGAMFATMTGI
                     KDTTVRFQKNVKLWPRLHVIGVMAGAFALLLFLTLVLDFNHIFTYLFGFVLASLFASV
                     MIYAARVLSDQTPTWQEPLLVTYLADISYGIYLFHWPFYIIFTQLMSNWLAVILTVFF
                     SVVFSTLSYYIIEPLIQGKTPQLFGLAIDCNPYKKWLSGLALGLFLLMVGTCLTAPRV
                     GNFETQLLVDSLQQSQSNLNKTHTLAAGDAHALSDVSIIGDSVALRSSDAFSKLMPTA
                     QLDAAVSRNFSEAFELFENHIQSKSLSKTTVLAVGVNSLYNYAQDIQGFIYALPKGHR
                     LVIVSPYDAKNAAQVAEAREHLLQLAKKYSYVTVADWYKAAVENPNIWYGSDGVHYNN
                     DAKLKGADLYVSTIQAAVERAAKKDAK"
     gene            complement(8491..8892)
                     /locus_tag="TV188_001647"
     CDS             complement(8491..8892)
                     /locus_tag="TV188_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1534979.1"
                     /translation="MKAIINNIQKWQITRTKLEIISVLVIIVCGLSVFTLTISSKASL
                     TYDNGQIKYTGYVLNHRMNGKGKLVYPNGDTYVGDFNKGVFDGEGTFTASTGWSYSGQ
                     FKKGQADGKGTLKAKDSKVYKGTFKQGIFQK"
     gene            complement(8898..9356)
                     /locus_tag="TV188_001648"
     CDS             complement(8898..9356)
                     /locus_tag="TV188_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEL1534980.1"
                     /translation="MKKVCFVCLGNICRSPMAEFVMKSMASPDELQVESRATSGWEHG
                     NPIHHGTQSLLQQYQISYDTKKTSQQITSFDFEAFDYIIGMDSHNIRDLKQMSKHQWD
                     SKIHLFIEGGVPDPWYTGDFEETYRLVKAGCQHWLSQISAEHESHVEIDE"
     gene            complement(9597..10604)
                     /gene="ruvB"
                     /locus_tag="TV188_001649"
     CDS             complement(9597..10604)
                     /gene="ruvB"
                     /locus_tag="TV188_001649"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEL1534981.1"
                     /translation="MTRILDNDLIGDEGSVERTLRPQYLREYIGQDRVKDQLMIFIEA
                     AKRREESLDHVLLFGSPGLGKTTMAFVIANELGVHLKQTSGPAIEKAGDLVAILNDLE
                     PGDVLFIDEIHRMPMAVEEILYSAMEDFYIDIMIGAGDTSRSVHLELPPFTLIGATTR
                     AGMLSNPLRARFGITGHMEYYQTADLTEIVERTADIFDMTIKHEAAYELARRSRGTPR
                     IANRLLKRVRDYAQIMGDGMITTQITDKALTMLDVDQEGLDYVDQKILRTMIEVYQGG
                     PVGLGTLSVNIAEERDTVEDMYEPYLIQKGFIMRTRTGRVVTEKAYQHLGYPYEKTIK
                     T"
     gene            complement(10638..>10712)
                     /locus_tag="TV188_001650"
     CDS             complement(10638..>10712)
                     /locus_tag="TV188_001650"
                     /inference="COORDINATES: protein motif:HMM:NF038244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system DWW-type pheromone"
                     /protein_id="HEL1534982.1"
                     /translation="LFLAALFLLHSAQLLSDIDWWRVG"
BASE COUNT         3282 a         2396 c         1881 g         3153 t
ORIGIN      
        1 tacatacaca cactactatc tgaaacaata attcactact tgaattagat atactatcta
       61 gtatttttcc cagttgaata gaaaataagg tcattaaaaa tgcactgatt acactaaaaa
      121 aagctactat tacatataac aatctatgac ttcttacaat ttctttcata aatccaccta
      181 aaagatttta taaataaatt ataatgtaca agtatcgtat cctaaaaaac ttcccttatt
      241 cgggacacaa catttttcat ctatatttta aatcatacta ccttgttact aaaaacgtag
      301 ataataattt agcttataac ccatgttttt agcaatatgt tatgtcatta ttcttttttc
      361 ctacagtgct tcctaaaatt tgtgaagacg aattgtcaaa ttaagtgcaa cgcttttcca
      421 taaaagagtt tataaggtag tttccagtta ggacatcttc tagaacgatc atttcattta
      481 tcttcccact cttatatgat agagctctca atatcagtca agtcagttcc tttaggaaac
      541 tactctttga ttaacccatt ggtattttca tttgtcctac gttatcaagg ggtgtgagga
      601 gcagagaaat aaacttctag attgagttcc tgtgttaatc tctaatattg ttcaaaccca
      661 gtatctctat cagaggttac aatatgtcca actttctctg gtactgtctt tcaaggggca
      721 atcatggtat taataactag ctggctcttt tacatcttta gataccaagc tttttttacc
      781 agttagtttc accaaaaaag cccttagaaa attaattcta aggactttat tcatcatttg
      841 ggacaatcag cttgtctggc tgctgacttt ttctgaaatc agccttaaag cgtgaaatcc
      901 aatacctttc ttccttgaat gagaccacgt tccatttcgt caaagacttc tggagcagtc
      961 tcaactggaa ccttttctac aactggcaca accagacctt ctgcaccaaa ggcaaaggct
     1021 tcttccaagt ctttacgagt tcccacaagt gatccgacta ccttgattcc gtctaggaca
     1081 gtctttacga tagataattc catgtattct gatggaagtc ctacagcaac aacagttcct
     1141 cctgcacgca cactatcaat agcttggtta aaggctactt tagaaacagc ggttaccaca
     1201 acgccatgag caccacctgt tttttcttgg atatagccgg caacatcttc gatttcttta
     1261 ccattgacaa cgatatctgc tccaacctcc ttggccagct ctagcttatc attgttaatg
     1321 tccactgcta cgacatgagc attgaaaacc tttttagcat actgaacagc taggttacca
     1381 agtccaccgg caccaaagat aacaatccat tgtcctggag cggcacctgc ttctttgata
     1441 gccttatagg ttgtaacgcc tgcacaggta attgatgatg cttgagctgg gtcaagacca
     1501 tctggcactt tcacagcata gtcagctgta acaactgcat actcactcat cccaccatca
     1561 actgaatagc cagcattttt gactgaacgg catagagtct cgcgacctgt tgtacaatat
     1621 tcacaatgac cgcagccttc aaagaaccaa gcaattgata cacgatcacc aacctttaag
     1681 gaggtaacgc cttcacctag cttttcgaca ataccgatac cttcatgacc gaggatacgc
     1741 cctggaacct gaccaaaatc accatgcgca acatgcaagt cagtatgaca tacgccacaa
     1801 tattctactt taacaagagc ttctccatga ccgattgatg gtacatcatg ctctacaacc
     1861 tctacaccac tgctggtttg gttaacaact acagccttca taggatgcct ccaatttcta
     1921 agtctcggtt tatctatttt tgcaaccgtt tacaatttgt attgtatact ttttcacaag
     1981 gtttgtcaac caatttcttg aaagttttct gaaaataaac ttaaccagtt aagttggcta
     2041 aaaaacagca tctagaccat tccaaatgct gttgtcactt ttatctattt ataccttatt
     2101 cctttaggct gtaatgtcat tttcaataat cactttaagg gcgttattac tgccggcatt
     2161 tttaaagacc tcataggctt tttcaacctc tgacagctta aagtgatgtg ttaccatctt
     2221 agttgcatca atcttaccag atttcaacac attcaatagc atttctgttg tattagcgtt
     2281 tactaggcca gttgacattg taatgttttt gatccatagg tcctgtaggt ccaaactaac
     2341 tggttttcca tggacaccaa cgttagaaac atgcccgcca atagcaataa tcttttggca
     2401 aatatcaaag gtagcaggat agcctacaca ctcaatggca acatcaacac ctcgaccatc
     2461 agttaattca tggacttttt tgacaatatc atcaaggtca ccagagcaaa tcgtatctgt
     2521 tgctccaaag cgcttagctg cttctaaacg tgattctgac aagtcaacca tgatcagctt
     2581 agctggtgaa taaaattgtg ctgttaaaag agctgctagt ccgataggac ctgctccaac
     2641 gatacacact gtatcacccg gctttacctt tgcagactga acgcctattt cataggaagt
     2701 tgggaaaatg tctgacagca taaccaaggc atcatcctca acggttttag gagcatgata
     2761 aagactgcca tctgcttgag gaatatgaac atactctgct tgtgtcccat taatcaaatg
     2821 ccctagaatc cagccaccgc tttcacaatg agcaggaatt ccttttttac aataatagca
     2881 ggtattacag gctgtgatac aggaaataat aaccttatca cctaccttaa agttgttcac
     2941 tgcagagccg actgactcga caataccaat accttcatga cctaaaatgg taccatgagt
     3001 agtctctggg acatctccac ctaaaatatg taagtctgtt ccacagattg ttgttttcaa
     3061 taaacgaacc acagcatctg tcggagcaag aatctctggt tttggttgat caataagctc
     3121 cagctgacct ggagcaacat atgtagctgc tttcataaaa cgtctccaaa tttagtctag
     3181 aaaatgtaat cgattacatt tttagtataa ttttttacac cctctttgtc aattaataaa
     3241 gggtaatttt agaaaaagtc tgacaatacc attattttgg tttttgtttg atatataaag
     3301 gtttttaacg ctattaacat cattaaaaaa gcaatcactc cttgttttat tagaaaataa
     3361 agctcatcag atagacgcaa catgttattt tcttcagcta attgctaagt gcagctaagt
     3421 cgtaactatc agccacttta tgaatatggc aaatgaagct tccccctctg atggaatgct
     3481 ctgtaaaacc attgtcttaa aagctttata tgatatctga gaaactaccc ctgagttaag
     3541 ctatctcaac acaaggcact gccgactttt tcatctaaca cagccctttt catagctaga
     3601 taaaaaaata gaagccaagc agctcctatt tttactatta atgattgata ttatttccga
     3661 cgtcctggac gctctgcgta accataataa gcatcattca tgatttcttc catgtgctca
     3721 accattggca agcgtgggtt agcaggtgag cattgatcct cgtaggcaag ataagcaagc
     3781 tcacgagtgt gtgccttcca ttcttcctca tcaattcctt gatctctgaa attcatctta
     3841 atgcctaagc gacagccaag atcataaaca gctttagcat aagattcaac accttcttct
     3901 ggagtagatg ccggaagtcc tagcaactta gcaatgtctt gatatttttc atcggcgcga
     3961 tagtaattgt acttaggcca tgttgctgtt ttagcaggac gggtaccatt gtaacgaata
     4021 acgtatggaa gcaagatagc attggtacgt ccatgaacag tatggaattg tgcaccaatc
     4081 ttatgagcca ttgagtgaga aatacccagg aaggcattag caaaggccat acctgccatt
     4141 gttgaggcat tatgcatttt ttcacgtgac tcaaagtcag cttccttaac agatttttca
     4201 aggttttcaa agacaatctt aatggcttga agggccaaac catctgtaaa gtcattagcc
     4261 atttgtgata cgtaagcctc ggttgcgtgg gtcaacacgt ccatacctgt atcagctgca
     4321 atgaagcctg gtactgtaag caccaacgcc gggtcaacaa tggctaccgt tggtgtcaat
     4381 gaatagtcag caattgggta cttgcggttg ttggccttat ctgagataac agcaaacggt
     4441 gtaacctctg atcctgtacc tgaggttgtt ggaatagcca caaattttgt tttcttacca
     4501 agctcaggga acttgaaggc acgtttacga atatccatga atttttgaac aagatcatgg
     4561 aagtcaacct ctggttgctc atagaataac cacattacct ttgcagcgtc cattggagaa
     4621 ccaccgccaa gagcgataat cgtatctggc ttgaaggtac gcatcagctc agtacctttc
     4681 ataaccgttg tgatatcagg atctggctca acatctgcaa aaatttgata aacaacctta
     4741 ttacgacgaa ggtcaagctg ctcgatgata cgatctaaga agccaagctc aaccatagcg
     4801 tggtcggtaa caatcatcac acgctcaacg tcacgacatt tttgaaggta ttgaattgaa
     4861 tcacgctcga agtatgtttt tgaaggaact ttaaaccatt gcatattatt tctacgtctt
     4921 cctacttttt tgatgttcaa gagatttaca gcactaacat tatcaccaac tgagttacgt
     4981 ccataagaac cacagcccaa tgttaatgac ggtaggaagg cattataaac atcaccgata
     5041 ccaccaaatg tagaaggtga attccaaatc acacgaatag cacgaatttt tgttccaaat
     5101 tccttagcta agtctgcatc agcagtatga atagcggctg agtgaccaag tccgttaaat
     5161 tcaaccattt gacgagcctt ttcaacacca tctgtgcgag attcagcctt caaaacagcg
     5221 ataactggtg acaatttttc acgtgttaat ggctcatttt cagaaacttc cttacattct
     5281 gctgcaagga tattcgttcc ttctggtact gtaaagcctg cctgctcagc aatccaagct
     5341 gctggcttac caacaatatt agggttcagc ttagcacctg cacagttttt actgttagcc
     5401 ttagcaccaa agcagaattc ctctaacaga gccttttcct ttttgttgac aaagtaagtg
     5461 tggtaagact taaattcact aacaaactcg tcataaatct ccttgtcgat aataacagcc
     5521 tgctcagaag cacaaaccat accattgtca aatgatttag acatgacaat atcgtgtgct
     5581 gcctgacgaa tgttagcgga tttttcaaca taggcaggca cgttaccagc accaacccca
     5641 agagctggct taccacatga gtaggctgcc ttaaccatag cattaccacc agttgcaagg
     5701 attgttgcaa taccatcatg attcatcaga gcgttagttg cttctagtga tggggtttca
     5761 atccattgaa cacagtcctc aggagctcct gctgcaatgg ctgcatcacg aacaatgcgt
     5821 gctgcatgag ctgatgattc ttgagctgat gggtggaagg caaaaataat agggttacgt
     5881 gtttttaagg agattaaaga tttaaaaata gctgttgacg ttgggttagt tgttggggta
     5941 atcccacaaa taacacctac tggctcagca attaaggtca aacctgttac atcgtcttct
     6001 tcaatgatac ctactgtttt ttggtgacgc atgttattaa caacgtgctc acatgcgaaa
     6061 aggtttttgg tagccttatc ttcaaaaact ccgcgaccag tttcttcata ggcatgctta
     6121 gctaactcac catgtgcgtc caaagcagca acagaggcct tcgctacaat gtagtcaacc
     6181 tgttcttgag ttaactgacg cattttatca agcgctacta aacctttttg aacaagagcg
     6241 tcaattgttg cggcaacaga tgttgtttca acagtactat ttttttcagt catttgagac
     6301 tcctttacct tgttaaaagt ttcacaattt tgtttacaaa aatattatat cattttttgg
     6361 cattttgtaa atcatttcac aataaaattg tgatgttttt tcaatcaatt tccgaaactc
     6421 tttgataaca aggggtttgg cttggtggat tttttctgaa ataatggctg acgcattcac
     6481 tttgttccga aagcgctttc ttttttagat caggctaaat tatttaatga tccgttttta
     6541 aaagcacgtc accgtcagca ataacagcca ataatgacac tgtctaacag gtggagcttt
     6601 atctcgcgct aaagggcgca agacgatcta aaaatcacat catgaaaagg cttgatctgt
     6661 ttgtaagacc aagccttcgt tattaattct taacaaattg ttgttagcac cactatttag
     6721 catctttttt tgctgctcgc tcaacagccg cctgaatcgt tgagacatat aagtcagcac
     6781 cttttaattt ggcgtcgtta ttgtagtgga ccccatcact accataccag atattgggat
     6841 tttcgactgc cgccttgtac cagtcagcaa ctgttacata gctatatttt ttagctagct
     6901 gcaacaaatg ctctctagcc tctgctacct gtgctgcatt cttagcatca tagggcgaca
     6961 caatcaccaa gcgatgcccc tttggtagtg cataaataaa gccttgaata tcctgcgcat
     7021 aattataaag agaattaaca ccaacagcta aaaccgttgt ttttgataag ctcttggatt
     7081 ggatatgatt ttcaaaaagc tcaaaggctt cactgaaatt gcggctgaca gcagcgtcta
     7141 gttgagcagt cggcattaat tttgaaaaag cgtcactaga cctcaaggca actgagtcac
     7201 caataatgct aacatcacta agagcatgcg catctcctgc tgccaaagta tgtgtcttat
     7261 tgagattact ttgagattgc tgcaaggaat ctactaaaag ctgggtctca aaattaccga
     7321 cccttggtgc tgtcaaacag gtaccaacca tcaacaaaaa gagtcctaaa gcaagccctg
     7381 ataaccattt cttataggga ttacaatcaa ttgctaaacc aaaaagctgt ggtgtcttgc
     7441 cttgaatcaa aggctcaata atgtaataag aaagcgttga aaacactact gaaaagaaaa
     7501 ccgttaagat cactgccagc cagttagaca tcagctgtgt aaaaataatg taaaatggcc
     7561 aatggaataa ataaatccca tagctaatat ccgcaagata ggtcacaagc agtggttcct
     7621 gccaggttgg tgtttgatcg ctcaaaacac gcgcagcata aatcattacc gaagcaaaaa
     7681 gactggctaa gacaaaaccg aaaagatagg taaagatatg gttaaaatct aacacaagcg
     7741 ttagaaacaa caacagagca aaagcgccag ccatcactcc aataacatgt agccttggcc
     7801 acagcttaac attcttttga aagcgaacag tcgtgtcctt aattcccgtc atggttgcaa
     7861 acatcgctcc taaaaagaaa ggaaagctgt gtgaaagcgt tgaaaagtaa acagaagaaa
     7921 aatctgatac aaagaaggct ctgataaaca tgctgaagta gctaagcgtg aacactgcgg
     7981 aagaaattaa aaacagaatg cctctaaatt tcttctgact gtagcctttt ttagctaata
     8041 accaaaccaa cagcccccaa agcaaataaa aatgcacctc aatggccaag ctccaggtat
     8101 gcacaaacag atgcggaatg aattgacttt catagctact gcctgtcagt agctcataac
     8161 tatttgttgt aaaccctagg gcagctgcta tttgctgacc gataccagca atgaagtcac
     8221 ttttgactaa aaaagtaaag ggaattgtca agagaattaa caagacaagc ggcggtacaa
     8281 tacgataaaa acgccttcta aaaaaagcaa ccacatcaat ggtttgtttt gagacatatt
     8341 catcaatcaa caaggctgta atcaaatagc ctgaaaaagt aaagaagatg tcaacgccaa
     8401 caaagcctcc tgaaaaagta tgcttaaaaa agtgatagag caacaccagc aaaagacctg
     8461 ttaccctaat aaacgaaaac cattttatcc tcatttttga aatatcccct gcttaaaggt
     8521 tcctttgtaa acctttgaat ccttcgcctt caaagtaccc ttgccatcag cctgaccttt
     8581 tttaaattgt ccgctgtaag accaccctgt actagctgta aacgttcctt ctccatcaaa
     8641 gacaccttta ttaaaatccc caacataggt atcgccatta gggtaaacca atttcccttt
     8701 accattcatt ctatgattaa ggacatagcc ggtgtacttg atttgcccat tgtcataggt
     8761 caagcttgct tttgaggata tggtcaaggt aaaaaccgac aatccacaga caataatcac
     8821 aaggactgaa ataatctcta gctttgtccg agtgatctgc catttttgaa tgttatttat
     8881 tattgctttc attactatta ctcatctatt tccacatgtg attcatgttc agcgctgatt
     8941 tgactcaacc aatgctgaca gcccgcttta accaagcggt aggtttcttc aaaatctcct
     9001 gtataccaag gatccggaac gcctccttca ataaaaagat ggatcttgga atcccactga
     9061 tgcttggaca tttgcttcaa atctctgata ttatggctat ccattccgat aatatagtca
     9121 aaggcttcaa agtcaaagct ggtgatttgc tgagaggttt tcttggtatc atagctaatc
     9181 tgatattgct gtaatagcga ttgtgtccca tgatgaattg gattgccatg ctcccagcca
     9241 gaggttgcac gactctccac ctgtagctca tcaggactgg ccatactttt catgacaaat
     9301 tcggccatag gactacgaca aatatttcca agacaaacaa agcatacttt tttcatgaaa
     9361 aactcctttt acctattata gcaaaattat agggccaaaa ggagaaatcg ctcttataat
     9421 tttcgttcaa ttgatctaaa aatgtttttt aatgctttgt ctagtgaaag cacctctgct
     9481 tccctgacca atcacccctc acctcacatc gttttacttt tttactcagt aagctattga
     9541 caatacaaaa gacttgacac cggtaaaaac aaaggaatca agtcttacat agctatttat
     9601 gtcttaatgg ttttttcata gggatagcct aagtgctgat aggctttttc ggtgacaact
     9661 cggcctgttc tggtacgcat gataaaaccc ttttgaatta aataaggctc gtacatgtct
     9721 tctactgtat ctcgctcctc tgctatattg acagatagag tcccaagacc aaccggccct
     9781 ccttggtaca cctcaatcat ggtacgaaga atcttttggt ccacataatc taaaccttct
     9841 tgatccacat ctaacatcgt tagagcctta tctgtgattt gagtcgtaat cattccatca
     9901 cccataattt gagcataatc acgcaccctt tttaacagcc gattagcaat acgaggggtt
     9961 ccacgactcc tgcgtgccag ttcataagcg gcctcatgct tgattgtcat gtcaaaaata
    10021 tcagctgtac gctccacaat ctctgttaaa tcagctgtct gataatattc catatgccca
    10081 gtaatcccaa aacgagccct caaaggattt gacagcatgc ctgcacgagt cgttgctcca
    10141 attaatgtaa agggaggcag ctccaaatgc acactccggc tagtgtctcc agcgccaatc
    10201 atgatatcaa tgtaaaaatc ctccatggca ctgtacaaga tttcctcaac agccatcggc
    10261 atacgatgaa tttcatcaat aaagaggaca tctcctggct ctaaatcatt caaaattgcc
    10321 accaaatcac cagctttttc aatggctggg ccagaggtct gcttgagatg aactcccaat
    10381 tcattggcaa tgacaaaggc catcgttgtt ttacccaagc ctggggaacc aaataacagg
    10441 acatgatcca aggattcctc acgcctcttg gctgcctcaa taaaaatcat cagctggtct
    10501 ttaaccctat cctgaccaat atactcacgt aaatactgtg gacgtagtgt cctctcaaca
    10561 gatccttcat cgcctatcag atcattatct aaaattcttg tcatagagct attatagcat
    10621 aaatagatga tttagcttta accaacacgc caccagtcaa tatcactaag taattgggca
    10681 gaatgaagta gaaataaagc agctaaaaac ag
//
LOCUS       DARYYD010000062        10357 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.063, whole genome shotgun sequence.
ACCESSION   DARYYD010000062 DARYYD010000000
VERSION     DARYYD010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10357
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.063"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..191)
                     /locus_tag="TV188_001651"
     CDS             complement(<1..191)
                     /locus_tag="TV188_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEL1534983.1"
                     /translation="MSQTYERIMVAIDGSHGSELAFHKGVNVALRNGAALILTHVVDT
                     RALQSVATFDSYIYDKLEQ"
     gene            478..1692
                     /locus_tag="TV188_001652"
     CDS             478..1692
                     /locus_tag="TV188_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1534984.1"
                     /translation="MKIIEKSSKLEHVAYDIRGPVLDEANRMIANGEKILRLNTGNPA
                     AFGFEAPDEVIRDLILNARSSEGYSDSKGIFSARKAIMQYCQLKGFPDVDIDDIYLGN
                     GVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGHAVHYLCDEEAEWYPDIAD
                     IKAKITERTKAIVIINPNNPTGALYPREVLEEIVAIAREHQLIIFADEIYDRLVMDGG
                     EHIAIASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKRHVRGYIEGLNMLANMRL
                     CSNVLAQQVVQTSLGGRQSVDELLLPGGRIFEQRNFIYQAINAIPGLSAVKPKAGLYL
                     FPKIDRNMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKEPDHFRVVYLPTVEELADVQ
                     EKITHVLKQYKR"
     gene            1864..2646
                     /gene="codY"
                     /locus_tag="TV188_001653"
     CDS             1864..2646
                     /gene="codY"
                     /locus_tag="TV188_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001133183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEL1534985.1"
                     /translation="MPNLLEKTRKITSILQRSVDSLETELPYNTMASRLADIIDCNAC
                     IINGGGSLLGYAMKYKTNTDRVEEFFETRQFPDAYVKAASRVYDTEANLSVENELTIF
                     PIESKDIYPDGLTTIAPIYGGGMRLGTLIIWRNDNEFSDDDLVLVEISSTVVGIQLLN
                     LQTENLEETIRKQTVVNMAINTLSYSEMKAVAAILSELDGNEGRLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVINEGIFDKLKEF"
     gene            3263..3820
                     /locus_tag="TV188_001654"
     CDS             3263..3820
                     /locus_tag="TV188_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEL1534986.1"
                     /translation="MKALISIDYTNDFVADDGSLTAGAPAQVISEAMASVVEAAFEAG
                     YYIFFAIDAHEEGDSFHPEAALFPPHNIIGTRGRDLYGPLMTVYTRYQQDQRVFWLDK
                     RHYSAFSGTDLDIRLRERGVTTLVLTGVLTDICVLHTAIDAYKLGYKLEIITSAVASN
                     STENHQWALNHCRTVLGAKLLDRLS"
     gene            4294..4596
                     /gene="gatC"
                     /locus_tag="TV188_001655"
     CDS             4294..4596
                     /gene="gatC"
                     /locus_tag="TV188_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008086915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEL1534987.1"
                     /translation="MKISEEEVRHVAALSKLSFSESETTEFATTLSKIVDMVELLNEV
                     DTTGVAITTTMADKKNIMRADIAEAGVDRKLLFQNVPEKENHFIKVPAILDDGGDA"
     gene            4596..6062
                     /gene="gatA"
                     /locus_tag="TV188_001656"
     CDS             4596..6062
                     /gene="gatA"
                     /locus_tag="TV188_001656"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEL1534988.1"
                     /translation="MSFNHHTIEELHELLVAKDISAVELTKATLEDIKAREEAVGSFI
                     TIACEAALKQAAALDAKGIDPDNVMSGIPLAVKDNISTKGILTTAASKMLYNYEPIFD
                     ATAVANAYDKDMIVIGKTNMDEFAMGGSTETSYFKKTKNAWDHSRVPGGSSGGSATAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGVVGLKPTYGAVSRYGLIAFGSSLDQIGPFAPTV
                     RENAQLLSVIAGSDRKDSTSAPVQIADYTIKIGQDIKGMKIALPKEYLGEGIDPKIKE
                     TVLAAAKHFEKLGAIIEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGFRAADA
                     KSLEDIYVKTRSQGFGDEVKRRIMLGTFSLSSGYYDAYFKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPTAAFELDTLNHDPVAMYLADLLTIPVNLAGLPAISIPAGFADGLPVG
                     LQLIGPKYSEEVIYQVAVAFEATTDYHKQQPMIFGGDR"
     gene            6062..7501
                     /gene="gatB"
                     /locus_tag="TV188_001657"
     CDS             6062..7501
                     /gene="gatB"
                     /locus_tag="TV188_001657"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEL1534989.1"
                     /translation="MNFETIIGLEVHVELNTNSKIFSPSSAHFGEDPNASTNVIDWSF
                     PGVLPVMNKGVIDAGIKAALALNMSIHQHMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIDITLEDGSTKKIRIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEIIQYTGISDVKMEEGSMRVDANISLRPYGQEAFGTKTELKNLNS
                     FSNVRKGLEFEVERQAKILRSGGVIRQETRRYDEASKGTILMRVKEGAADYRYFPEPD
                     LPLFEIDDAWIEDMRAELPRFPADRRASYINALGLSAYDAGQLTATKALSDFFEQAVA
                     LGGDPKQVSNWLQGEMAQFLNAEGKTIDQIALTPENLVEMIAIITDGTISSKIAKKVF
                     VHLAKHGGSARAYVEKAGLVQISDPAVLIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQIAQQLLAQELQKLLD"
     gene            7730..8674
                     /locus_tag="TV188_001658"
     CDS             7730..8674
                     /locus_tag="TV188_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEL1534990.1"
                     /translation="MSRNGKGSTMILLAGIAWGLSGVSGQYLIAHGVGINALTSLRLI
                     ISGLVLSAMAYVRQREAVISLLKDKRLLRELLIYSLFGLTLNQYAYLLAIRYSNAGTA
                     TVLQYLSPILVLVYLSFKSRRLPAVGESCAICLAILGTVIMACHGDLSHLAINPIGLF
                     WGLFAAVTYAYCVIKPAKLIADWGSLLIVGLAMLMGGVIFPILTRAWQYPLAMTYGNL
                     RALFGIIGIGTIFAYTFFLKGASIIGPIKATLLASIEPVASVCFAIILMKEIFHPIDL
                     LGMALILIAVLVISLRDLLLTKRKKQLALNIKRPPSSD"
     gene            8725..8964
                     /locus_tag="TV188_001659"
     CDS             8725..8964
                     /locus_tag="TV188_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1534991.1"
                     /translation="MVWSLIVGAIIGMVAGRITEKSHSMGCFTMTAAGLIGSAVGQKL
                     FGDWGIQLAGMAVFPSILGAAIVIIVASALFGKKQ"
     gene            9161..10276
                     /locus_tag="TV188_001660"
     CDS             9161..10276
                     /locus_tag="TV188_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KxYKxGKxW signal peptide domain-containing
                     protein"
                     /protein_id="HEL1534992.1"
                     /translation="MRKTEGRFRTWKSKKQWLFAGAVVTSLLLGAALVFGGLLGSLGG
                     SSHQARPKEQPVSSIGDDDKSHKSSSDSMVSRPPKKDNLQPKPSDQPTNHQHQATSPS
                     QPTAKSSGHHGNQPQSLSVNSQGNSSGQASEPQAIPNQGPSQPLGLRGGNSSGSGHHH
                     QPQGKPQHLDLGKDNSSPQPQPKPQGNSPKLPEKGLNGENQKEPEQGERGEAGPPLSG
                     LSGNNQGRPSLPGLNGENQKEPEQGERGEAGPPSTPNLEGNNRKNPLKGLDGENKPKE
                     DLDGKGLSGENDESPKLKDEHPYNHGRRDGYRVGYEDGYGGKKHKGDYPKRFDESSPK
                     EYNDYSQGYNDNYGNGYLDGLADRGGKRGYGYSYNPD"
BASE COUNT         2825 a         2076 c         2516 g         2940 t
ORIGIN      
        1 tcctgctcca acttgtcata aatgtagcta tcaaaggttg caacgctttg cagcgcacgt
       61 gtatcaacaa catgggtcaa aatcaaggca gcaccattac gcaaagcgac attaaccccc
      121 ttgtgaaagg ctaattcgga gccatgagag ccatcaatag cgaccatgat acgttcatat
      181 gtttgtgaca tcggtttatc ctcctttgaa ctttatctct atagctatta tacctttttt
      241 gaggagaaat tgaaaacgtt ttaatgattt tctgagctat tgttcaccaa atagcccagc
      301 tattccctga ggtgaggata ccttgagcta gaagctagct tagatagcct tattaatagc
      361 tgctgcttag cttgcttaga gctttggttg agcttttggc attctttaag ctcatagaaa
      421 agtgctttct attttaattg ttttggttta taatatgggt tacgaggtaa tgagactatg
      481 aaaataattg aaaaatcatc aaaattagaa cacgtagcct acgatattcg aggtccagtc
      541 ctggacgagg ctaatcgtat gatagctaat ggtgaaaaga tccttcgatt aaatacaggt
      601 aacccagcag cctttggctt tgaggctcca gatgaggtta ttcgtgattt gattctcaat
      661 gctcgctcca gcgagggcta ttctgatagc aaggggattt tttcagctcg taaggccatc
      721 atgcaatatt gtcagctaaa gggctttcct gatgttgaca ttgatgatat ttatttggga
      781 aatggtgtct cagagctgat ttcgatgtct cttcaagcct tgctcgataa tggtgatgag
      841 gtgctggtgc caatgcctga ctatcccctt tggacagcct gtgtcagcct aggtggtggg
      901 catgcggtgc attacctgtg tgatgaagag gctgaatggt atcctgatat tgctgacata
      961 aaagccaaga tcactgagcg cacaaaagct atcgtcatta tcaatcccaa taacccaaca
     1021 ggtgctctct accctcgaga ggtcttagag gagattgttg caattgccag agagcatcag
     1081 cttatcattt ttgcagatga gatttatgat cgtttggtca tggacggtgg ggagcatatc
     1141 gcaattgcca gccttgcacc tgatgttttt tgcgtgtcaa tgaatgggct gtcaaaatca
     1201 caccgtattg ccggctttcg agtgggctgg atggtcttgt caggccctaa aagacatgtc
     1261 agaggttaca ttgaaggctt gaacatgctg gcaaacatgc gcttgtgctc caatgtctta
     1321 gcgcagcagg tggtgcagac ctccttagga ggacgtcagt ctgttgatga gctcttgctt
     1381 ccgggtggtc gcatctttga gcaacgtaac ttcatttacc aggccattaa tgccattcca
     1441 ggcctatcag ctgtaaagcc taaggcaggc ctctatttgt ttccgaaaat tgatcgaaat
     1501 atgtaccgca ttgatgacga cgaggaattt gtcctacagc ttttgaagca agaaaaggtc
     1561 atgctggtac atgggcgtgg cttcaactgg aaggagcctg atcattttcg cgtggtctat
     1621 ctgccaacag tagaagagct agctgacgtg caagaaaaga tcacgcatgt tctcaagcaa
     1681 tacaagcgct aatatgattc tcatacaaaa attggatcgc gagatccttt ttgtttttca
     1741 gcaaaataag gctctggcct catccgaatt gtaggtataa tagccaattt tctgataatt
     1801 ccttgcaaaa gctagggtcc tttgatataa ttgtaacgca aataattaaa aggaaaagaa
     1861 aaaatgccaa atttattaga aaaaacccgt aagattactt ctattttgca acgttctgta
     1921 gacagcttgg aaacagaact cccctataac actatggctt cacgcttagc agatattatt
     1981 gattgtaatg cttgtatcat caatggtggc ggcagcttac ttggctatgc gatgaagtac
     2041 aagaccaaca cagaccgcgt cgaggaattt tttgaaacaa gacagttccc agatgcttat
     2101 gtcaaggcag ctagtcgtgt ttatgacact gaagcaaacc tttctgtgga aaatgaacta
     2161 acgatttttc ctattgagtc aaaggatatc tatcctgatg gtttaaccac gattgcccct
     2221 atctatggtg gcggcatgcg cttaggtacc ttgatcatct ggcgtaacga caatgaattc
     2281 agtgatgatg accttgtttt agttgaaatc tcaagcactg tggtcggtat tcagctgtta
     2341 aatcttcaaa cagaaaacct agaagaaacc attcgtaagc agacagttgt taatatggca
     2401 atcaacactc tatcttactc tgaaatgaag gctgttgcag ctatccttag tgagctagat
     2461 ggcaatgaag gacgcctgac cgcttcagtg attgcagatc gtattggaat cacacgatct
     2521 gtcatcgtga atgcccttag aaagctagag agtgcaggta tcattgagag tcgctctcta
     2581 ggaatgaaag gcacttatct caaggtgatt aacgaaggca tctttgacaa gctaaaggaa
     2641 ttttaatagc tcagatgcga tcgtctgcta agcccaaggc ttgcctttag ctttgctagc
     2701 tgtgattagt cagagcaggt agtgaaagtg ttagctatga tcaaagtctt gctgcttata
     2761 gagcagccat tcattagcca gagccctgct tggtaagggc tagacttggt ctttatgacg
     2821 gcttatcgga gtttcttagc agctgtggag gacttcacac attattatag cgtcccctca
     2881 aaggttctag cattggctgg cttttgaggg gtattttttg tattttcgct gtgattcagc
     2941 atgagatgaa catgacagat gcatgaaaga tttttagcaa gaaaataagg ctttctgtat
     3001 ttcaatgttc agctatttca ggaatatatc ttattttcat atagaaaaac gttgaaagtg
     3061 tctacttaaa tctatactat agttcagaaa taactgtttt tcgcctttat cgtgtataaa
     3121 tcaatccgct gtcttgacag ctgtcgtgtt tagtggtaaa ctataagtgt ctaatcatac
     3181 tgaatattaa aagcaggctt agttcttatg gcttgctgtc atgcagctaa gagagcataa
     3241 gctttttggg gagggataag ctgtgaaggc cttgatttct attgattaca cgaatgactt
     3301 tgtagctgat gatggtagcc tgacggcagg agcacctgct caggtgattt cagaggcgat
     3361 ggctagcgtt gttgaggctg cctttgaggc cggctactat atcttttttg cgattgatgc
     3421 ccacgaggag ggagatagct ttcatccgga ggcagccttg tttccgccgc ataatattat
     3481 cgggacaagg ggtcgggacc tgtatggtcc tttgatgacc gtatatacca gataccagca
     3541 agatcagcgg gtcttttggc tggataagcg gcattattct gccttttcgg ggactgattt
     3601 ggatattcgt cttcgtgagc gtggcgtcac gacgctggtc ttgacaggtg tgctgacgga
     3661 tatttgtgtc cttcatacag cgattgatgc ctataaattg ggctacaagc ttgagattat
     3721 cacatcagca gtggcgagca attcaacaga aaatcaccag tgggcgctga accactgtag
     3781 gactgtccta ggagcaaagc ttcttgatcg gctttcttag gcgatcgttc gatcagctgg
     3841 gataggctaa tcaagtaagg cagtattagc tgctgcttgg ctcagcgctg atcttaaggg
     3901 cttcttagtg agatcttttg gtcttggcta ggaggctttt tgttattaag tttttcgcta
     3961 atcccagcta cgcatacacg tgaataaaat gcaggtagct atgctctagc cacattgccc
     4021 ttttaacctc atcaattgct caaatgcagt ttagttatag cctggctgtt cttgaaaaaa
     4081 gcaggttgag cttatgaaaa acgttatcag aaaacgtcag ttgccacatg catttgacgt
     4141 gaaatcccag cagtccgcta tggtaaataa agctaattat gatataatgg ttaagactat
     4201 gtaaaattgg gttattcagg ctattatcaa gcgtttgaaa cagcaaggcc ttgtggctga
     4261 tgatggtctg ctttaccttg gataggagaa ttcatgaaaa tttctgaaga agaggttcgc
     4321 cacgttgcgg ccctatcaaa gctatccttt tcagaaagtg aaacaactga gtttgcgaca
     4381 acattatcaa aaatcgttga catggttgaa ttgctaaatg aagtggatac gacaggtgtt
     4441 gccattacca ccacaatggc agacaagaaa aatatcatgc gagctgatat cgctgaggct
     4501 ggagtggatc gcaagctcct gtttcaaaat gttcctgaaa aagaaaatca tttcatcaag
     4561 gtaccagcta ttcttgatga cggaggagat gcctaatgtc ttttaatcat catactatag
     4621 aagaattaca tgagcttctt gttgcaaagg acatttctgc agttgagcta acaaaggcaa
     4681 cccttgagga tatcaaggcg cgtgaggagg ctgtgggttc tttcattacc attgcttgcg
     4741 aggctgcttt aaagcaggct gctgcacttg atgctaaggg gattgatcct gacaatgtga
     4801 tgtcaggaat accactagct gtcaaggaca atatctcaac caaggggatt ctgacaactg
     4861 ctgcttctaa gatgctttat aattatgagc cgatttttga tgcgacagcg gtagctaatg
     4921 cctacgacaa ggatatgatt gttattggta agaccaatat ggacgagttt gctatgggtg
     4981 gctcaacaga aacgtcttat ttcaagaaaa ccaaaaacgc ttgggatcat agcagggttc
     5041 ctggtggttc atcaggtggc tctgcaacag cagtagcttc aggtcaggtt cgcttatctc
     5101 ttggctcaga cactggcggc tctattcgtc agccagcagc ctttaatggt gttgttgggc
     5161 ttaagccgac ctatggggct gtttctcgct atggcttgat tgcctttggc agctcgctag
     5221 atcagatagg gccttttgcg ccaacggtaa gagaaaatgc ccagctgcta tcggtcattg
     5281 cagggagtga ccgcaaggac tcaacctcag cacctgtaca gatcgctgac tacacaatta
     5341 agatcggtca agacatcaag ggcatgaaga ttgcactacc taaggaatac cttggcgaag
     5401 gcattgatcc taagattaag gagacggttt tggctgctgc taagcatttt gagaagctag
     5461 gagctatcat tgaggaggtc agtctgccac atagcaagta tggggtggct gtctattata
     5521 tcatcgcttc atctgaggcc tcatcaaacc tacagcgctt tgatggtatt cgctatggct
     5581 ttcgtgctgc tgatgccaag agccttgagg acatctatgt caagacgcgt agtcagggct
     5641 ttggtgatga ggttaagcgt cgtatcatgc ttggtacctt tagcttatca tcaggctatt
     5701 acgatgctta tttcaaaaag gcaggtcagg ttcggacgct gatcattcaa gactttgaga
     5761 aggtttttgc tgattatgac ttgattttag gaccaacagc accaacagca gcctttgagc
     5821 ttgatacgtt gaatcatgat cctgttgcca tgtatttggc tgatcttttg accattccgg
     5881 tgaatctagc gggcttgcct gcaatctcta ttccagcagg ctttgcagat ggcttgcctg
     5941 ttgggcttca attgatcggt ccaaaatata gcgaagaggt catctatcag gtagcggtag
     6001 cctttgaagc gactactgac taccacaagc agcagcctat gatttttgga ggtgacaggt
     6061 aatgaatttt gaaaccatta ttggacttga ggtccatgtg gagttgaata ccaattctaa
     6121 gattttctca ccttcatcag ctcattttgg agaggatcca aatgccagca ctaatgtgat
     6181 tgactggtct ttcccaggtg tccttccagt gatgaacaag ggagtcattg atgcgggaat
     6241 caaagcagca cttgctctta acatgtctat tcatcagcac atgcactttg accgtaagaa
     6301 ttatttctac ccagacaatc ccaaggccta tcagatttca cagtttgatg agccgattgg
     6361 ctacaatggc tggattgata ttactcttga ggacggctca accaagaaaa tccgtattga
     6421 gcgtgctcac ctagaagagg atgccggcaa aaatacgcat ggtacagatg gttattccta
     6481 tgttgacctc aatcgtcagg gagtgccctt gattgagatc gtctcagagg ctgacatgcg
     6541 ctctccagag gaggcctatg cttacctgac tgccctaaag gaaatcattc agtatactgg
     6601 tatttctgat gtcaagatgg aagaggggtc catgcgtgtg gacgccaata tctccttgcg
     6661 accatacgga caagaggcct ttggtacaaa aacagaattg aaaaacctga actcatttag
     6721 caatgtgcgt aaggggcttg agtttgaggt ggagcgtcaa gccaaaatcc tacgctctgg
     6781 cggtgttatt cgtcaggaga cacgtcgtta tgacgaggca agtaagggaa cgattctcat
     6841 gcgtgtcaag gagggagcag cagactaccg ctatttccca gagccagatt tgccattgtt
     6901 tgagattgat gacgcatgga ttgaggatat gcgtgcagag cttccaagat ttccggcaga
     6961 caggcgagct agctacatta atgctcttgg cttgtcagcc tatgatgcag gtcagctgac
     7021 agcaacaaag gctttgtctg atttctttga gcaggctgtg gcacttggtg gtgatcctaa
     7081 gcaggtgtct aattggcttc agggtgagat ggctcaattc ttaaatgctg agggcaagac
     7141 gattgatcag attgccttga ccccagaaaa tctcgtggaa atgattgcga tcatcactga
     7201 tggcacgatt tcatcaaaaa tcgccaagaa ggtttttgtt catttggcaa agcatggcgg
     7261 ctcagcgcgt gcttatgtgg aaaaggccgg cttggttcaa atttcagacc cagctgtctt
     7321 gattccaatc attcatcagg tgtttgctga caatgaggct gctgtggcag atttcaaatc
     7381 aggcaagcgc aatgctgaca aggcctttac tggttttctg atgaaggcca caaaggggca
     7441 agccaaccca cagatagctc agcaattgtt agcccaagaa ttgcaaaaat tgctggatta
     7501 aggagtcgtt atgactggca ttgagtctga aacagagttt tcaggctctt tatgatggta
     7561 ggctctttag gacaattctg tgataatacc tcgctatccg aagctgtaag aggtagctta
     7621 tcggtctgtt gttaatgact gttaagcagg cttggtgaag tctaggctag agctatcaag
     7681 gtattatgag tggccttatc atggcatgga ttaaaaagag gaagataata tgtcaagaaa
     7741 tggaaaaggc agtaccatga ttttactagc cggaatcgcc tggggtctct caggggtgtc
     7801 agggcaatat ttaattgctc atggggtcgg catcaatgcc ttgacctcac taaggctcat
     7861 tatttcaggg cttgtgctgt cagctatggc ttatgtgcgg caaagagagg ctgtcatcag
     7921 cttactcaag gacaaaaggc ttttaagaga gctgttgatt tacagtctat ttggtctcac
     7981 acttaatcaa tatgcctatc tgcttgctat tcgttactct aatgctggta cagccacagt
     8041 cctgcaatac ctttccccca ttttggtgct ggtctaccta tcgttcaaat caagacgcct
     8101 gccggctgtg ggagagagct gtgctatttg cctagcgatc ctaggaacgg ttatcatggc
     8161 ctgtcatggt gatctttccc atctggcaat caatcctatt ggacttttct gggggctttt
     8221 tgcagcggtg acctatgctt actgtgtcat caagcctgct aagctgattg ccgactgggg
     8281 gagcttgctg attgttggtc ttgccatgct gatgggagga gtgatttttc cgatcctgac
     8341 aagagcatgg cagtacccat tggcaatgac ttatgggaat ctacgggccc tgtttggcat
     8401 tatcggtatt gggacaattt ttgcctacac cttttttcta aagggggctt caatcattgg
     8461 accgatcaag gctaccttgc tggcttcaat tgagccggtt gcctctgtct gctttgcgat
     8521 tatcctgatg aaagagattt ttcaccctat tgatctgtta ggaatggcct tgattttaat
     8581 agcagtgctt gtgatatcgc tgagagactt attgcttact aagagaaaaa agcagcttgc
     8641 tcttaatatc aagcgaccac catcatctga ctgatataag gcaagggtat ggtataataa
     8701 gacaaaacat aaaggagatt tgcgatggtt tggtcattaa ttgttggagc tattatcggc
     8761 atggttgcag gtaggataac agaaaaaagc cattcgatgg gctgtttcac aatgactgct
     8821 gctggtttga taggctctgc agttggtcaa aagctgtttg gcgactgggg tattcagctg
     8881 gcaggcatgg ctgttttccc ttcaattcta ggagcagcta ttgtgataat tgttgcttca
     8941 gcgctctttg gcaaaaaaca ataagccagg agtacttgtg acgttcaaat atataaaaat
     9001 ccttgtatca gtatgatacg aggatttttt ggttatcaga tttgtaaaaa caatcgaata
     9061 tatcagatga taaaaattta aaagaaatat gataaagtct tgactatata tactatttct
     9121 tggtattttt accaaaaaat atggagagag ttaaaaaagt atgagaaaaa cagaaggacg
     9181 ttttcgcaca tggaagtcca aaaaacaatg gctatttgcc ggtgcagtgg tgaccagctt
     9241 gctgctggga gctgcacttg tctttggagg tttattagga agtcttggtg gctcatccca
     9301 tcaagcgagg ccaaaggagc agccagtcag ctcgattgga gatgacgata agtcgcacaa
     9361 gagctcatca gattcaatgg tcagtcggcc accgaaaaag gataacttgc agcctaagcc
     9421 ttcagatcag cctactaatc atcagcatca ggctactagc ccgtcccagc cgacagcaaa
     9481 gagctcaggt catcatggga atcaacctca gtctctcagt gtgaacagcc aaggaaatag
     9541 tagtggacag gcctcagagc ctcaggctat tcctaatcaa gggccttccc agccactggg
     9601 gctgagagga ggtaacagct ctggttcagg tcatcaccat cagccacaag gaaagccaca
     9661 gcacttagat ctaggtaagg ataattctag cccgcagcct caaccaaagc ctcagggcaa
     9721 tagtcccaag ctgccagaaa aaggcttgaa tggtgaaaat cagaaggaac cggagcaagg
     9781 tgaacgaggt gaggctggtc ccccactttc agggttgagt ggtaataatc aaggccgtcc
     9841 ttcgcttcca ggcttgaatg gtgagaatca gaaggaacca gagcaaggtg aacgaggtga
     9901 agccggtccc ccatcaactc cgaatttaga aggaaataat cgtaaaaatc ctttaaaagg
     9961 attagatgga gagaataagc caaaggaaga tttagacggt aaaggcttaa gcggagaaaa
    10021 tgatgaatca ccaaaactta aagacgaaca cccctacaat catggtcgtc gtgatggtta
    10081 ccgagttggc tatgaggatg gatatggtgg caaaaagcac aaaggagatt atcctaagcg
    10141 gtttgatgag tctagtccaa aggaatataa tgactatagt caagggtata atgataatta
    10201 tggaaatggc tatttagatg gtctagctga tagaggtggt aagagaggat acggctattc
    10261 ttacaatccc gactaatctt ctgctatccc ttaattaacc tacaaaaaag ctgggcttcc
    10321 ttagacccag cttttttggc agcttcaaac gtcttat
//
LOCUS       DARYYD010000063        10267 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.064, whole genome shotgun sequence.
ACCESSION   DARYYD010000063 DARYYD010000000
VERSION     DARYYD010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10267
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.064"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            6..596
                     /locus_tag="TV188_001661"
     CDS             6..596
                     /locus_tag="TV188_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1534993.1"
                     /translation="MEGITKSYGAKLILKDFSYTFEQGKKYLIKGASGRGKSTLLHII
                     KGTAVDSGKIAFITKDNHSFESYQANIGMVSQAPFLFNGTLEENICLNQEFSKENILA
                     VLDQVHLLEELPAGLGFQIENNGTNISGGQRVRIELARFLLRQKDILLLDEVTAALDK
                     DNARRVRELIFSLPITIIEVAHHVDQAIAYDDMIEL"
     gene            606..2168
                     /locus_tag="TV188_001662"
     CDS             606..2168
                     /locus_tag="TV188_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1534994.1"
                     /translation="MFKYFNKYLVTLTLVACALNSLVFLIEPLITSKIFDLTFLNNHQ
                     DTLSFLGYGLTLYVVLYSVMFIANLLINHIMTIGCGRIRLRLYQNLILNYREMSHDKK
                     ISMLTQDVEYYLWNHISPSILLVSHVSNVLLLSAYLLSKNMLIGLIFIACAFVFLVVQ
                     HVIGQKAEQKGSELAVARQKLLGLLSDVVAGHSTLIQNQALFASLKQVKKQSEHYESS
                     RQAFEIFRSFFTLLAHLMLFISQFLPIFLGLALTLLGVKLRTTDLIAMFIAATRLEQP
                     LKNIVDDMFRLNGAKAIAKHFETLLEQPIPKYQSHAMTGDPFECLDGHHLAKSFAGRT
                     LFSDLSFHFEKGKKYLIKGSSGSGKSTLFKLILQEMSPDEGTLDMVLTGGQTTDNYHH
                     RIGLIAQSPYLFNDSIRYNLTLGEAFSDELLLEKLEQVGLTDEFDDILNHQIVNNGEN
                     ISGGQKTRLEIARSLIRQKDVLLADEVTAPLDVKNAKTIRQLLFSLPVTVIEIAHHID
                     DTFIYDGDIDLS"
     gene            2551..3652
                     /gene="prfB"
                     /locus_tag="TV188_001663"
     CDS             join(2551..2622,2624..3652)
                     /gene="prfB"
                     /locus_tag="TV188_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658142.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEL1534995.1"
                     /translation="MEVAEMRQQIVENKEKLTSFRRSLDLERLEEDIALLENKMTEPD
                     FWNDNMAAQKTSQELNELKLTYQTFHDMQELSDETELYLEMLDEDDSVKEELEASLIK
                     LSQMLASYEMTLLLSEPYDHSNAILEIHPGSGGTEAQDWADMLFRMYTRFGNAKGFKV
                     ETLDYQAGDEAGIKSVTLSIEGPNAYGFLKSEMGVHRLVRISPFDSAKRRHTSFVSVE
                     VMPELDDTIEVEIRDDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVASTVDRT
                     QYGNRDRAMKMLQAKLYQLEQEKKAEEVNALKGDKKEITWGSQIRSYVFTPYTMVKDH
                     RTNFEVAQVDKVMDGDIEGFIDAYLKWRMGED"
     gene            3703..4395
                     /gene="ftsE"
                     /locus_tag="TV188_001664"
     CDS             3703..4395
                     /gene="ftsE"
                     /locus_tag="TV188_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014294955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEL1534996.1"
                     /translation="MALIEMKGVSKKYRRSTTALRDINVSVNQGEFVYIVGPSGAGKS
                     TFIKLLYREEKLSSGSLKVGEFDLTKLRGREVPILRRSIGVVFQDYKLLPKKTVFENV
                     AYAMEVIGERRRHIKKRVPEVLDLVGLKHKMRSFPNQLSGGEQQRVAIARAIVNNPKL
                     LIADEPTGNLDPEISWEIMHLLERINLQGTTILMATHNSHIVNTLRHRVVAIENGRIV
                     RDEEKGDYGYDD"
     gene            4388..5317
                     /locus_tag="TV188_001665"
     CDS             4388..5317
                     /locus_tag="TV188_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003059499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1534997.1"
                     /translation="MIRHFFRHIWESIKNLRRNLLMTFASVSMVTVTLTLLGVFAATL
                     LNIQRVASGVENNIQINAYLQVDSTDAAKMVQSINGEQINNENYHKIYDQIAGLKGVE
                     RIIFSSKDEQLQKLQDSLGDVWGMYNEDSNPLQDIYIVETKTPKQVKSVTKAIKKIQG
                     IEDADYGGINSDKLFKFSKLIQTWGIIGTLLLLFIAIFLISNTIRMTIMSRQRDIAIM
                     RLVGAKNSYIRGPFFFEGAWVGLFGAILPSLIIYYGYEFAYKHFTPELQHNSLSMYPI
                     NPYVYYLIGMLFVIGIIIGSLGSVLSMRRYLKF"
     gene            complement(5707..6348)
                     /locus_tag="TV188_001666"
     CDS             complement(5707..6348)
                     /locus_tag="TV188_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1534998.1"
                     /translation="MTIMTLMNPVAGENTYLLVNDEAILVIDPGSKGQAILSQIHAIN
                     KPVAAILLTHTHYDHIMSLELVRESCQHPPVYVAKEEADWLYKPEMNLSGLIRHADLP
                     DIICKPAEKLFQYQTPYQLAGFHFSVVPTPGHSAGGVSFIFEQEEAVFTGDALFRESI
                     GRTDLPTGNLEQLLASIRDKLLTLPNHYQIYPGHGSATTISHEKNSNPFLRQR"
     gene            6685..9156
                     /locus_tag="TV188_001667"
     CDS             6685..9156
                     /locus_tag="TV188_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEL1534999.1"
                     /translation="MINEFSQKYAVIDLEATSPGPTASIIQVGIVIVEGKEIVDSYQT
                     DINPHEPLSDHIKALTGITDQQLAQAPDFSQVARTIFELIEDCVFVAHNVTFDANLLA
                     EALFLEGYDLLTPRVDTVELAQIFYPSLEKYSLSHLSEVLDLNLSDAHTAIADAQATA
                     NLFIKLLHKIESLPRECLETLLLYADSLLYETAMIVRQALAVSRPYSTSDYIKINQIL
                     LKKPDQLTKPYQLSQSFEINAALLGLEERPKQLSFAKIVEETLFQTEPAFIEAQAGIG
                     KTYGYLLPLLAQKHQTQILVSVPTKLLQDQIMANEVRAIQEQFHIDCHSIKGPANYIK
                     LDSFQESLNQLDDNRLVNRYKMQLLVWLLETRTGDLDEIKQKQRFAAYFDQIKHDGSI
                     QQTSPFYAYDFWQQSYQRAKSARLLITNHAYFLHRIQDDKAFAKGKILVFDEAQALML
                     QLEELAHQRLNIADTLQELQEQLAVPSSLLEQRLLEGIAFELNQLSSHYHQEEEKQQA
                     QASQHLLRLQEHVKELGAAASQSLKQLFKQQEMDYWVSSEQQADKRQTFLNGSSRTVL
                     QFKALLPEIFKAYFVSATLQISPSISLADLLGFDTYSYHQLAKEKSTQQLVVIDQDMP
                     LIKDLTDEAYTQTIAARLLVLHQQQQVPILVLFNAKKHMLMVSDYLEANQVQHLTQGK
                     NGTAYHIKKRFDRGEQSMLLGLAAFWEGVDFVHADRMIEVITRLPFDNPEDIATQKMQ
                     RYLQAAGKQPFNDYFLPMTILRLKQAIGRTLRRKEQKSAVLILDRRILTMSYGQTILH
                     SLEEEFLISQQNFQDSLAEIGDFLI"
     gene            complement(9330..>10267)
                     /locus_tag="TV188_001668"
     CDS             complement(9330..>10267)
                     /locus_tag="TV188_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEL1535000.1"
                     /translation="MYVDNRLKTGSWKPDTEANKEAIYKTHFKKYLGKTKMKDISRIE
                     YENHINGMRKNYSKNTLRLIHSVLNAMLNHAVTNKMLDDNPIDGITIGDSEIIPVNKR
                     ISLEEFKEWDSWAKKSLIQYDYTIVRMTYFGARSSEVVAIKIGNLTKLENGRYRILLD
                     ESRTYHRPNGGGMKTPGSERFMEVDLETSHYIDDVVVESKRIAKKYNRILSKEDYLFL
                     TNFKNAKKELLGMPISIRRVYKLFNTVNEKSGMHVTPHMMRHFFATQGQIAGVPIEHM
                     AAALGHSTSYMTSKYTHIKEEVAGSVTDRFMSALN"
BASE COUNT         2909 a         2018 c         2278 g         3062 t
ORIGIN      
        1 tggctttgga agggatcaca aagtcctatg gcgccaagct gatccttaag gatttttcct
       61 atacctttga acaggggaaa aaatatttga taaagggtgc cagtggtaga ggtaagtcga
      121 ctctgttaca cattattaag ggaactgctg ttgactcagg taaaatagcg tttatcacca
      181 aagacaatca ctcatttgaa agctatcaag ctaacattgg catggtgagt caggcacctt
      241 ttctctttaa tggcaccttg gaagagaata tctgtctgaa tcaggagttt tccaaggaga
      301 atatccttgc tgtcttggac caagttcacc tgttggagga attaccagct ggtctaggct
      361 ttcagataga aaataatggg accaacattt cgggcggcca gcgagtgcgc atagaattgg
      421 ctcgattttt gctacgtcag aaggatattt tattgcttga tgaggtcaca gcagccttgg
      481 acaaggacaa tgctcggcga gtaagggagc tgattttttc tcttcctatt accatcattg
      541 aggtggctca tcatgtggat caagctatag cttatgatga tatgatagaa ttgtaggtga
      601 ttaagatgtt taagtatttt aataaatatc tagtgacact aacgcttgtt gcatgtgcct
      661 taaacagtct tgtctttctg attgaaccct tgatcactag taagattttt gatttaacgt
      721 tcttaaataa tcatcaagac accttgtcct ttttaggcta tggtctgacc ttatacgtgg
      781 tcttatattc tgttatgttc attgctaatc ttctgatcaa ccatatcatg acgattgggt
      841 gtggtagaat caggttgcgt ctctatcaga atttaatctt aaattatcgg gagatgagtc
      901 atgacaagaa aatttctatg ctgactcaag atgtagaata ttatctatgg aatcacatca
      961 gccctagcat tcttctcgta tcacacgtga gtaatgtcct tttgctcagt gcttacctgt
     1021 tatcaaaaaa catgctaatt ggtcttattt ttattgcatg tgcttttgta tttttagtgg
     1081 ttcagcatgt gattggtcaa aaggcagagc aaaaaggtag tgagctggca gtagcgagac
     1141 aaaagctgct tggcttatta agtgatgtgg ttgcggggca ttcgacatta attcaaaatc
     1201 aagctctttt tgctagcctc aaacaggtaa aaaaacagtc agagcattat gagagctcac
     1261 gtcaagcatt tgagatattt aggtctttct ttaccctatt ggcacatctg atgctgttta
     1321 tttctcaatt cttgcccatt tttttaggct tagccttaac cttattaggt gttaagctga
     1381 gaacaactga tcttattgcc atgtttattg cagcaacgcg cttagaacag ccactcaaaa
     1441 atattgttga tgatatgttt aggcttaatg gtgcaaaagc cattgctaag cattttgaga
     1501 cacttttaga gcagcctatt ccaaaatacc agtcgcatgc tatgacaggt gatccttttg
     1561 aatgcttaga tggtcatcat ctggcgaaat catttgcagg taggacctta ttttccgatc
     1621 tctcttttca ttttgagaag ggaaagaaat acctgattaa gggatcaagt ggatctggta
     1681 aatccacact ctttaagctt atcttacagg agatgagtcc tgatgagggg acactagata
     1741 tggtattgac tggaggtcag acgactgata attatcacca tcgcataggg ctgattgcgc
     1801 agtcgcctta tctttttaac gatagcattc ggtataattt gaccttgggg gaggcgtttt
     1861 ctgatgagtt gcttttagaa aagctagaac aggttggctt gactgatgaa tttgacgata
     1921 ttttaaacca ccaaattgtt aataacggag aaaatatctc aggtggtcaa aagacacgtc
     1981 ttgaaatcgc aagaagcctc attagacaaa aagatgttct tctagcagat gaagtgacgg
     2041 ctccacttga tgtcaaaaat gctaaaacta tccgacagct actatttagt ttaccggtaa
     2101 cagttattga aattgctcat catattgatg acacctttat ctatgacggt gatattgatt
     2161 tatcgtagaa aatatcatca cattgcttag aaataataat tgatgcttat gaaattgtca
     2221 ttcacacagt gaatggcttt ttcttaggct aaattttcca tgtggagctt gatctgatag
     2281 gctatctgag aaaaaaagct aacaacagcc atgttttttg gggctatgac tgttctaata
     2341 cgagctgcct ctagctgctg gtatataaga ggtgacatga ttgtcacaat tcgtcatcat
     2401 tttgtcgtta aatttttaca tagatttctt atgctagtca tggcagagct ccttacccta
     2461 aaaagaaggg aatttagctg atgggaaata gcaattctaa agcctttatg ataaaatgaa
     2521 aaaagacact ataatagaag aggtaactgt atggaagtgg cagaaatgcg ccagcaaata
     2581 gtagaaaaca aagagaagtt gactagcttc aggaggtctc tttgacttag agcgtttgga
     2641 ggaggatata gctctcttag aaaataagat gacagagcct gatttttgga atgataatat
     2701 ggcagctcaa aaaacctctc aggaattaaa cgagctcaag ctcacctatc aaacctttca
     2761 tgatatgcag gagctatctg atgagacaga gctttattta gaaatgcttg acgaggacga
     2821 tagcgtcaag gaagagctag aagcaagcct gattaagctc agccagatgc tagcaagcta
     2881 tgaaatgacg ctgcttttgt ctgagcccta tgatcatagc aatgcaatcc tagaaattca
     2941 cccaggttca ggtggcactg aagcacaaga ctgggcagac atgctttttc gcatgtacac
     3001 tcgctttgga aatgccaagg gctttaaggt agaaactctg gactatcaag caggagacga
     3061 ggcaggaatt aagtctgtga ccctttctat tgaagggcca aatgcttatg gcttcttaaa
     3121 atcagaaatg ggagtacatc gtctggtgcg tatttctcct tttgactctg ctaagcgtcg
     3181 tcacacctcc tttgtttcag ttgaagtcat gccagagctt gatgatacca tcgaggtgga
     3241 gatacgtgat gatgacatta agatggacac cttccgctca ggtggtgctg gtgggcaaaa
     3301 tgtcaacaag gtctcaactg gggtacgctt gacccatatc ccaacaggaa tcgtagtggc
     3361 gtcaacagtt gaccgcaccc aatatggcaa ccgtgatcgc gctatgaaaa tgcttcaagc
     3421 caagctttat cagttagagc aggagaaaaa ggcagaagag gtcaatgccc tcaaggggga
     3481 taaaaaggag atcacctggg gcagtcagat caggtcctat gtctttacgc cttatacgat
     3541 ggtgaaggat catcgtacca attttgaggt ggctcaggtt gataaggtga tggacggaga
     3601 tattgagggt tttattgacg cttatctcaa atggcgcatg ggtgaggatt aaagtgatcc
     3661 ccactcagat aaacactaac agcttagaga aggaagaata agatggcatt aattgaaatg
     3721 aagggtgttt ctaagaaata ccgtcgctcg acaacagctc tgagagacat taatgtctca
     3781 gtcaatcaag gggaatttgt ctatattgtt ggtccatcag gagctggtaa atcaaccttt
     3841 atcaagcttc tttatcgcga agaaaagcta agctcaggca gcctaaaggt gggtgagttt
     3901 gacttaacca agctaagagg acgtgaggtt ccaattttac gtcgcagcat tggtgttgtt
     3961 tttcaggatt ataagttgct ccctaaaaaa acggtctttg aaaatgttgc ctatgctatg
     4021 gaggttatcg gagagagacg tcgccatatc aaaaagcgtg ttcctgaggt tctagacctt
     4081 gtcgggttaa agcataagat gcgctccttt cccaatcaat tgtcaggtgg tgagcagcag
     4141 cgtgttgcga ttgcacgcgc tattgtgaac aatcccaagc tcctcattgc agatgagcct
     4201 acaggcaatt tggatccgga aatttcttgg gaaatcatgc acctgcttga gcgtatcaat
     4261 ctacagggga caacgatatt aatggcaacg cataacagtc atatcgttaa tactcttcgc
     4321 catcgcgtgg ttgcgattga aaatgggcgt attgtccgcg atgaggagaa aggagactat
     4381 ggttacgatg attagacatt ttttccgtca tatctgggaa tctatcaaaa atttaaggcg
     4441 taatctcctc atgacctttg cgtcagtcag tatggtgacc gtcaccttaa ccctgcttgg
     4501 ggtctttgct gcaaccctgc tgaacattca acgtgtcgct tctggcgtgg aaaacaacat
     4561 tcaaatcaat gcttacttac aggttgattc gacagatgct gctaagatgg ttcagtcgat
     4621 taatggagag cagataaata acgagaatta ccataagatt tatgatcaga ttgcagggct
     4681 aaagggtgtt gagaggatta ttttctcaag caaggacgag cagctgcaaa agctacagga
     4741 tagtctgggc gatgtctggg gcatgtataa tgaggatagt aatcctctgc aagacatcta
     4801 tatcgtagag accaagaccc ctaagcaggt caaatcagtt accaaggcca tcaaaaagat
     4861 tcaagggatt gaagatgcgg actatggtgg tattaattct gataagcttt ttaagttttc
     4921 aaaactgatt caaacatggg ggattatcgg aacgctgttg ctcctgttta ttgcgatctt
     4981 tctgatttca aataccattc gcatgaccat catgtctcgt cagcgcgata ttgcgatcat
     5041 gcgtctggtt ggtgcgaaaa attcttatat tcgtggccca ttcttttttg aaggggcttg
     5101 ggttggtctg tttggtgcga tattgccatc gttgattatt tattatggct acgagtttgc
     5161 ctacaagcat ttcaccccgg aattacagca taatagcctg tctatgtacc ctatcaatcc
     5221 atatgtttat tatttaattg gcatgctttt tgtgattggt attatcattg ggtcactagg
     5281 atcagtctta tctatgagac gttaccttaa gttttaattg aaagagcttc tagcctgtgt
     5341 gcctggactg gtaccctgcg gttagggctc tttttgcttt tggggcaatg cttgctagat
     5401 aagcaaacaa tagcttaagc ccataccatt aagtattggg cttaagctat tgttatagtt
     5461 gtttaggtaa tagaagcagc cggaacttga ggtgtcctat ctaggtcttg agctatagct
     5521 tttctggcta gttggtgttt cttcacgtaa cagcgatttg tcgaacgata aggtgctctt
     5581 cttgtgatag ctggcttgta gtgatcgaca ggtgctaagt caaattagcc atcctgatgg
     5641 actggagtca tagcttttgc tgctgcgcct ggttgggcat agactgggca tctcggtagc
     5701 ttgagcttat cgctgcctca gaaagggatt gctatttttt tcatggctaa tggtggtagc
     5761 tgagccatgc cccggataaa tctgataatg gttaggaagt gttagcagct tatcacgaat
     5821 gctagcaagc agctgttcaa gatttccagt cggcaaatct gttctaccga tgctttctct
     5881 aaacagagca tcgccagtaa acaccgcctc ctcctgctca aagataaagg aaacgccacc
     5941 ggcagagtgt cctggtgttg gcactactga aaagtgaaat ccagctagct gataaggtgt
     6001 ctgatactga aagagctttt ctgctggttt gcagatgata tcaggcagat cagcgtgacg
     6061 tatcagtcct gacaggttca tttctggttt ataaagccag tccgcctcct ccttggcaac
     6121 atagacagga gggtgctggc agctctctct caccagctct aggctcataa tgtgatcata
     6181 atgcgtatgg gtcagtagga tagcagcaac aggcttgttg atggcatgga tttgtgataa
     6241 aatagcctgc cccttgcttc ctgggtcaat gactaaaata gcctcgtcat tgacaagaag
     6301 gtaagtgttt tcacccgcaa cgggattcat cagtgtcata atagtcatac ccttagttta
     6361 ccaaaatctg actcaaaaga cagctcaaaa ccacctcttt tgataaaagt gatctgttta
     6421 atggttttga tggctaagcc aagatagctc cagcttaaag gctgcttttt ttaattaata
     6481 ggagcaaaaa ggagctgcct cagcgctaac agctaatcag agtattagct ctctagtgtc
     6541 atagcaagga agtaggctgg ggcgattaaa aggcttgata actagctttt tatgatactg
     6601 actagcccta ttgagctgag ctaagactgg tattgtcaga tttaggcaaa gcctgtcaga
     6661 aaacgtgcta taatagatag tactatgatc aatgagtttt cacaaaaata tgctgtgatt
     6721 gacctggaag ccactagccc aggtccaaca gcgtctatta ttcaggttgg cattgtgatc
     6781 gttgaaggaa aagaaatcgt tgattcgtat caaactgata ttaatcctca tgagcccttg
     6841 tcagaccata tcaaagcact cacaggtatt acagaccagc agctagctca ggcaccggat
     6901 ttttcacagg tagcaaggac catttttgag ctgattgagg actgtgtttt tgttgctcat
     6961 aatgtcacct ttgacgccaa tttgttggca gaagccttat ttttggaggg ctatgatctc
     7021 ctcactccta gagtggatac tgttgagctg gctcagattt tttaccccag cctagaaaaa
     7081 tacagcctta gccacctatc agaggtgcta gacctaaacc tatctgatgc tcataccgct
     7141 attgctgatg ctcaggcgac tgctaactta tttatcaagc tgcttcacaa gatagagagc
     7201 ttgccaagag aatgcttgga gactcttttg ctgtatgctg atagtctgtt atatgagaca
     7261 gctatgattg tgagacaagc ccttgcagtc agtcggcctt attctacgag tgactacatc
     7321 aagattaatc agatcttgct aaaaaagccg gatcagctaa caaagcccta tcaattatcc
     7381 cagtcctttg agattaatgc agccctctta ggtcttgagg agcgccccaa gcagctcagc
     7441 tttgcaaaga ttgttgagga gactcttttt cagaccgagc cagcctttat cgaggctcag
     7501 gcaggcattg gtaaaaccta tggctattta ctgcctctcc ttgcacagaa acatcagacc
     7561 caaatcttgg ttagtgtgcc aaccaagctg ctacaggacc aaatcatggc taatgaggtg
     7621 agggctattc aggagcagtt tcacatcgat tgccatagta tcaaggggcc tgctaattac
     7681 atcaagctag acagctttca agagagcctc aatcagcttg atgacaaccg cttggttaat
     7741 cgctataaaa tgcaattgct ggtttggctt ttggaaacaa ggactggtga tttagatgaa
     7801 atcaagcaaa agcaacggtt tgcagcttac tttgaccaga tcaagcatga tggcagtatc
     7861 cagcagacct cgccctttta cgcttatgat ttttggcaac aaagctatca aagggctaag
     7921 tcagctcgct tgctgatcac caatcatgcc tattttttac accggattca ggacgataag
     7981 gcatttgcca agggtaagat tctagtcttt gatgaagctc aggccttaat gctgcagcta
     8041 gaggagctag ctcatcagcg actaaatata gctgatacgc tccaagagct tcaagagcag
     8101 ctagctgtgc caagcagctt gcttgagcaa cgcttgctag agggcattgc ctttgagctc
     8161 aatcagttaa gcagtcatta tcatcaggag gaggagaagc agcaagctca agcctcacag
     8221 catttgctgc ggctccaaga gcatgtcaag gagctaggtg ctgcagcctc tcagagcctc
     8281 aagcagctgt tcaagcagca ggaaatggat tattgggtga gcagtgagca gcaggctgac
     8341 aagcgccaaa cctttttaaa tggcagcagc aggacggtcc ttcagtttaa agcattgcta
     8401 ccggagattt ttaaggccta ctttgtctca gctactctac agattagccc tagcattagc
     8461 ttggctgatt tattgggctt tgacacttat tcttatcatc agctggctaa ggagaaaagc
     8521 actcagcaat tggttgtcat tgaccaagac atgcccttga ttaaggactt gactgacgag
     8581 gcttacacac agaccatagc agcaaggcta ttagtgcttc atcagcaaca gcaggtacct
     8641 atcttagtgc tctttaatgc taaaaagcac atgctcatgg tttctgacta tttagaggct
     8701 aatcaggtgc agcacttgac acaaggcaaa aacggtacag cctatcacat caaaaagcgc
     8761 tttgatcgtg gtgagcaatc aatgctgctg gggcttgcag ccttttggga gggagttgac
     8821 tttgttcatg ctgatcgcat gatagaggtc attacccgcc tgccctttga taatccagaa
     8881 gatattgcca ctcaaaaaat gcagcgctac ctacaggcag caggtaagca gccctttaat
     8941 gattattttc tgccgatgac gatcttaaga ttaaagcagg cgattggtcg aaccctgcgt
     9001 cgaaaagagc agaaatcagc agttttgatc ttagatcgtc gcattctgac catgtcctat
     9061 ggtcagacca ttttgcacag cctagaagag gaatttctga tatcacaaca aaatttccaa
     9121 gatagtctag cagaaatagg cgattttttg atataatgaa aaatagtaat ttttatttag
     9181 ttattttaat ttatttattt tgcaaatgtt tatttatagg catttgcttt tttgtttaat
     9241 tgataccaaa taataaaaat ctataaattg tcggggaata tatcggggga tttgttaatt
     9301 taagcatttg tataaatttc cccgactaac tagtttaaag cgctcataaa tctatcagta
     9361 acactaccag caacctcctc ctttatgtga gtatatttgc tagtcatgta acttgtagaa
     9421 tgacctagtg ctgcggccat atgttcaatt gggacacctg ctatctgccc ttgggtggcg
     9481 aaaaagtggc gcatcatgtg tggggtaaca tgcataccag atttttcatt gacagtatta
     9541 aaaagtttat agactcgcct aatagagatc ggcattccta aaagttcttt tttcgcattc
     9601 ttaaagttag tcaaaaatag gtaatcctct tttgataata tacgattata cttctttgca
     9661 atccttttag actcaacaac aacatcatca atataatgcg atgtttcaag atcaacttcc
     9721 ataaaccgct ctgatcctgg cgttttcatt cctccaccgt ttggacgatg gtacgtccta
     9781 gactcatcta gcaatattcg atatctacca ttttcaagct ttgttaaatt gccaattttt
     9841 atggcaacaa cttcgctact acgagctccg aagtaagtca tacggacaat agtataatca
     9901 tattgaatca atgacttctt ggcccatgaa tcccactctt tgaattcttc aagcgatatt
     9961 cttttgttaa cgggtataat ctcactatcg ccaatagtta tcccatcaat tggattgtca
    10021 tctagcattt tattggtgac tgcatgatta agcattgcgt tgagtactga atggatcaag
    10081 cgtaaagtgt tctttgaata attcttacgc ataccattaa tatgattttc atactcaatt
    10141 ctagaaatat ctttcatttt agtcttgcct aaatattttt tgaagtgagt tttgtatata
    10201 gcttctttat ttgcttcggt atcaggtttc catgatccgg tctttaggcg attatctaca
    10261 tacatat
//
LOCUS       DARYYD010000064        10182 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.065, whole genome shotgun sequence.
ACCESSION   DARYYD010000064 DARYYD010000000
VERSION     DARYYD010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10182
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.065"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(484..2061)
                     /gene="cls"
                     /locus_tag="TV188_001669"
     CDS             complement(484..2061)
                     /gene="cls"
                     /locus_tag="TV188_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEL1535001.1"
                     /translation="MTIKKNKKVRYLLHKGKKGLLRGIFSRTTIIAALIVLQIFFLCQ
                     SYAWMEQYRVLIAIIERIFSISIVLYLVNSDMDAISRVTWLILIMIAPLLGSLFLIYT
                     KLDWGYRDLKQRINHLVDLSSPYLRDDDAILQALKGHTSTTYHLVQYLERSRGNFPIY
                     RKTQATYFPIGEAFFEGLKTQLLLAKSYIFLEFFIIAEGQMWGEILGILEKKVQEGVE
                     VRVLFDGMLELSTLSADYAARLERIGIKAKSFLPISPFISTYYNYRDHRKIVVIDGEV
                     AFTGGINLADEYINEVKRFGHWKDAGLMLKGEAVDSFLIMFLQMWSITEKRLIVEPYL
                     SQHTEEVASDGYVIPYADSPLDTDKIGRNVYIDILNHAKEYVYIMTPYLILDSETEHA
                     LRFAAERGVDIRIIMPGKPDKAVPYALAKTYYKGLITSGVKIYEYSPGFVHSKVFISD
                     DSKAVVGTINLDYRSLYHHFECATYLYRSSVIADIVQDFKETQASSKLVTESQLRQRP
                     WYQKLVGLLVKTIAPLL"
     gene            complement(2277..5617)
                     /locus_tag="TV188_001670"
                     /pseudo
     CDS             complement(2277..5617)
                     /locus_tag="TV188_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677995.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
     gene            complement(5931..7601)
                     /locus_tag="TV188_001671"
     CDS             complement(5931..7601)
                     /locus_tag="TV188_001671"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018375545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEL1535002.1"
                     /translation="MKSDIEIAQSVPLKPITEIVKKVGIDADDLELYGNYKAKLSFEK
                     IKSVEDNKPGKLILVTAINPTPAGEGKSTMSIGLADALTKIGKKTMLALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTAHNALSALIDNHLQQGNELGIDPRR
                     IIWKRVLDLNDRSLRQVIVGLGSPVNGVPREDGFDITVASEVMAILCLATDLKDLKAR
                     LANIVIAYRYDKSPVYVRDLKVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATSTALRLADYTVTEAGFGADLGAEKFLNIKTPNLPKAPDAVVIVATLRAL
                     KMHGGVAKADLTFENTAAVRSGFANLKRHVENIRKFNIPIVVAINEFVTDTKAEIQVL
                     KELCAEIAVPVELASVWAKGADGGIALANAVVKAITEESAAYKRLYADKDSLEEKLKA
                     IVTEIYGGRAVQFGPKAKNQLKQFAQFGWDQLPVCMAKTQYSFSDDPSLLGAPDQFDI
                     TIRELVPKTGAGFIVALTGDVMTMPGLPKIPAAMKMDVTEDGTAVGLF"
     gene            7799..8491
                     /locus_tag="TV188_001672"
     CDS             7799..8491
                     /locus_tag="TV188_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEL1535003.1"
                     /translation="MAMKLLITSGGTTEAIDAVRGITNHSTGQLGKIVAETFLAKGFD
                     VTLVTTKTSVKPAQQPHLTIREVTNVDQLMAILKEEVPKHDLLIHSMAVSDYSPVYMT
                     DFDTVAAADHLQTFLTASNKEAKISSAADYQVLFLKKTPKVISYIKEWNPNIRLVGFK
                     LLVNAPAEELISVARDSLHKNKADYIVANDLADIKANQHKAFLVNDKTVCSASTKEEL
                     AQLIYERIIAND"
     gene            8484..9029
                     /gene="coaC"
                     /locus_tag="TV188_001673"
     CDS             8484..9029
                     /gene="coaC"
                     /locus_tag="TV188_001673"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEL1535004.1"
                     /translation="MTKRITLAVSGSISAYKAADLTSQLTKKGYEVTVLMTQAATAFI
                     TPLTLQVLSKNPVHLDVMAEHDVKIVNHIELAKATDLFVLAPASANTIAHLAYGFADN
                     MVTSVALALPEATPKLIAPAMNTNMYLNPITQGNIKRLADLGFREIPPKTALLACGDR
                     GPGALADIDDMVTAISQQLAR"
     gene            9086..9658
                     /locus_tag="TV188_001674"
     CDS             9086..9658
                     /locus_tag="TV188_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1535005.1"
                     /translation="MNHNKSSEISRIAIFFAVMLVIHFISSWFFYIWPVPIKPTLVHI
                     PVIVASIMYGPRTGAILGGLMGIVSVITNTLVLLPTSHLFSPFVTNGNLASLMIAMLP
                     RILIGITPYYCYKLIKNELGLVLAGLVGSLTNTIFVLSGIFIFFPTASGDNVKTFLTT
                     IVSGNAITEMIVSAIVTITLIPALSKLKKS"
     gene            complement(9882..>10182)
                     /locus_tag="TV188_001675"
     CDS             complement(9882..>10182)
                     /locus_tag="TV188_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS1634 family transposase"
                     /protein_id="HEL1535006.1"
                     /translation="RPVYVWTEKHIQAHFLTCFIALVHLRLLQHQIDWQMSPERIITA
                     LNSAKVTPLQDNYYRLQESLDMQELNRLLGIEWAKGIVKFEELKHYAKNPYTTLK"
BASE COUNT         2972 a         2256 c         1918 g         3036 t
ORIGIN      
        1 tgacagagtg tttcctgaat ttttatattt ttcctctata aacttttctt gaaaaatttc
       61 ttttctgcaa ctatcgctat ggctttccta tttttcagaa caagttttcg catttcagaa
      121 atatcttgga aattttttct tcatgcgttt gtcgtagcta gaagcttatg gtatgacagt
      181 caatagataa gtttttcaca tcagtgctat tgttccatga taacataccc ccttagaaaa
      241 ggcagttatg ctatggatac gatgagactc acacctaaca cagtgagatg actaaacatc
      301 acaacaaaaa aagctgagag aaactctcag ctctcagggg cattcgtatc acgaatgtga
      361 taaaaaggtt cacacaaatt atcaaagtcg gctcctgcct taatgacctc cccagcacaa
      421 ctgtgattta aaaatcacaa tcgactcatc gcataggcct attatagcaa acatatcatc
      481 tctttacaag aggggggcta ttgttttaac caataaacca acgagctttt gataccaagg
      541 cctttgcctt agctgacttt ctgtgactag cttagagctt gcctgggttt ctttgaaatc
      601 ctgaacaatg tctgcaataa cagaggaacg gtaaaggtag gtggcgcatt caaaatgatg
      661 atagaggctg cgataatcca gattaatggt tccaacgact gccttagaat catctgaaat
      721 aaagacctta gaatgcacaa atcccggact atattcgtag attttaactc ctgaggtgat
      781 caagccttta tagtaggttt tagcaagggc ataaggaaca gccttgtcag gcttacctgg
      841 cataataatc cgaatatcca cccctcgctc tgctgcaaat ctgagggcat gctctgtttc
      901 gctatccaaa atcaggtatg gagtcatgat ataaacatat tccttagcgt gattcaagat
      961 atcaatatag acatttctgc caattttgtc agtatcaagt ggtgagtctg cataaggaat
     1021 gacatagcca tctgaggcga cctcctctgt atgctgggac agataaggct ccacgatcag
     1081 ccttttttcg gtaattgacc acatttgtaa aaacatgatc aaaaagctat caacagcctc
     1141 accctttagc ataagacctg cgtccttcca atgcccaaag cgtttgacct cattaatgta
     1201 ctcatcagct aggttaatac cgcctgtaaa ggccacctct ccatcaatca ccacaatttt
     1261 acgatgatcc cgataattgt agtaggttga aataaaaggc gagatcggca aaaaagactt
     1321 tgctttgata ccaatgcgtt caagtctggc agcataatcc gctgataagg tcgacagctc
     1381 tagcatgcca tcaaaaagaa cgcgaacctc tactccctct tgcaccttct tttctaaaat
     1441 tcctaaaatt tctccccaca tctgcccctc tgcaatgata aaaaattcta gaaaaatata
     1501 ggacttagcc aataaaagct gagtttttaa accttcaaaa aaggcttctc cgatgggaaa
     1561 gtaggtggct tgagtcttgc gataaatggg aaaattccca cgactacgct ctaaatactg
     1621 aacgaggtga taggtcgttg aggtatgccc cttcaacgcc tgtaaaatag cgtcatcatc
     1681 tctcaagtaa ggagaggaca aatcaactaa atggttaatt cgctgcttta ggtcacgata
     1741 accccagtct aatttagtgt aaataagaaa taaagagcct agtaaagggg ctatcataat
     1801 gagaatcagc caggtcaccc ttgaaatagc gtccatatcg ctattcacca agtacaagac
     1861 aattgaaatc gaaaaaatac gctcaataat agcaattaaa acacgatact gctccatcca
     1921 agcataggat tggcataaaa agaagatttg cagaacgatc aaagcagcaa taatggttgt
     1981 tctgctgaaa atccccctca gcaagccttt tttcccttta tggagcaggt atcttacttt
     2041 tttattcttt ttgatagtca accctccagc tttatttttt cttattatat cataaaactg
     2101 gaggtcatga tttaagtcgc tgctaaaagt ttcagcaatt ggtgcaagca ttaaaaaaag
     2161 acctcaatac ttcttttaca acttgtaatc ctcacaaaac ctactgcttt aacaaccaaa
     2221 aaaagattga aggagacatg cttccccttc aatccaagtc tcatcaggtg atgagattaa
     2281 ttatctgatt tctttttaaa taagcctaga gataggctag ctagtagcat acctaagcct
     2341 gctaataacg atgagcccta tgcctgctct gaggttttag gaagctcatg gctatgtgct
     2401 ggagccattg gtttgctgct atctggtgtc atggctagtg actgctgatc tgctttgcta
     2461 ttatcagaag actgatcttg atcagtagaa ccattgccct taggctgctg ctctggcatt
     2521 ggtgtctcag gctgtttgtc gtctttaatc tctggttcct tttggtttaa aaggtctgta
     2581 agagcaatcg cgttaaagtt gccaaattca tcttcaacaa ttaatgtcaa ggcagcaata
     2641 ttaacctcta cctcctcacc tgacagctct gacatcaccg ttgctggaat gctaaatgag
     2701 ccgtcctcag ccattgggaa gtagttcacc acaatatctg cttcctctcc ttctccaatc
     2761 tcgacaatat ggccaacctg aatacggtag gctgagaatt tagcagtgtc gatcttaagt
     2821 gttctggtag attcgtcata ggaagctgat tttggtagct ctggtaggct tgttttcact
     2881 tgaaccttaa agtcttgctt ttgagcctca gcaccatctg ctacaggagt ataccaaacg
     2941 cgataggtat agctaccatc tgctacaggc tgatcattgg cgtcttttcc actccatttt
     3001 gtatgctcaa agcgatacgg taacacaaca ccctcttgat agtatttctg ggctgaagaa
     3061 acaccacttt cccaaacgat ttgtccattg tgatcaagaa cctgagcttt aatatcctta
     3121 acgcttctta ggaatacccc ttggaagaga ataaaatcct tattaccatc atcatttgga
     3181 gaaatcaaga aggttctatc tgcctctttt gctattaaat ccttttgatc agctgactcc
     3241 tgtgttccta aaataatata tctttctgcc tcagggccta actcattgac cgttccattt
     3301 tttgtatcct gtgccaagaa atatgggctg acctgaccaa tcaaagcagt tagcttgctg
     3361 aatttctctg gtaatatgta tttacctgtt tcaggatctt gctcaagctt ttgataaaag
     3421 gcaccctgct caagcgtctc ataaatagga gtatctaagg ctggcaagtt agcaaaatca
     3481 cccctaaagc cactaaatgg aatactcatc aattcttcct tagtgtctaa attgtctgtg
     3541 aaacggacaa agccttcaag gaagtagcca tttggcattg cttttaacaa ttcagcagcg
     3601 taagccttag cgtcaacaga aacttgaata tgctgctggt cctcggtgat attaatttcc
     3661 tgccactctg aatcctttaa tgcttttggc tgcaaggtga agtgaccatc tttagtttga
     3721 tcagtgatta ggttgacttg gaaataaagc tttttaggcc cttgattttt cgatagggca
     3781 ttaacattta gattaatgac aaattcatct gcaatgttcc ccagattgat tttagggttt
     3841 tgcttctgat cagtaaggta atagctggct gctagtgcct tttgaccatc tacctcacca
     3901 gcaccctgct ggcgtggaga aatataagcc ttgttttctg tgctataaag tgttcttgct
     3961 gagctcatca acacagctct aacaagctga gaaagctcct tatcagaaag ctctgggaat
     4021 ttctctttgt aagctttatg tagcatggcc acaagccctg acaccatagg tgttgacatg
     4081 cttgtaccag tcttgtaatc atattggtta ccatgaactg cagagtagac attgacacca
     4141 ggtgctgaaa tatctggctt gatacgacct tctgctgtca caccccagct ggattggctg
     4201 ataacgcggc caccagcatt gctaagcatt ttctcatagg ccttattaaa tctaaagctt
     4261 tgaccttcct taagagcttg agcgtccttg tagctcataa agccaacagg aatgtgagct
     4321 tcctttggaa tagaggcctt ttcaatcgta aagcttcctt caagcgcatt gttattgtag
     4381 ataatcacac cgctagcacc agctttaaca gcattttcaa tcttttgata aaagctaagt
     4441 gagccgccac gttcaatcaa agcaaccttg cctttaatat caagaccagt aaagtgagag
     4501 gcttcaccga atttggcatc agccacaaag taatcctgat cagcatcaaa tgagtcgccc
     4561 tctgacataa agatcgctag tttttgacta ccgtctgcgg tcttagcatt aacagactgg
     4621 ctaatagcgt aaacaggatt ggaagccgca acactgataa cctcttcaaa aatagctgga
     4681 ctattaaggg taccaaaatc aggatttgct gctagaggct ctcgagttcc cataccaact
     4741 gcactctcat taccagctcc agcaaccaac aaaacaccct tttcttgagc ataggctata
     4801 gcctttttaa cgtcctcatg aaccgttgat aaggaatccg ctgtttttcc aaagctcatg
     4861 ctaatcactg tagctcctag attaaccgcg tctgtgatcg ccttagcata ggattttgca
     4921 aattgatccc tttctggggc accagtcacc ttcatcagca taagagaagc atttggtgca
     4981 atcccctcaa cacgaaggcc atttcctgct ggtgttttcc cattacctgc tgctatagcg
     5041 gcagtatggt taccatgacc attatcagcg gtcaagccgc caatatcatc tgattgcttg
     5101 gtgtaatcgt aggcaaaaat aattttttcg ttgtaccact taccgtatgt gattttctga
     5161 tcctgctttt tagcaagaaa tgcctcttta gcaggaatag tatcgctatt ttttaagtcc
     5221 gaatcaagct taaaggcgtc atgctcagga tcaaaggaaa catcaataac agcaataacc
     5281 gctccgcttc ccttttgtgt ttactcttgt agggctttag cgttgaccga gtcattcagt
     5341 gataaattgg tcggtgctgt gctctctggg ccttctgcaa aggctgatat ttctttttct
     5401 gttttagctt ctgtttctga agtcgcctgg ctgcttgaga attgtcatcc gtagcagtag
     5461 cttcaacagc tgcaactgga ttcacttgtg atacagaagc gtctaagtcc tgctgctcct
     5521 cagcaaatac agtctgacta tgaagcaata aaatacttgt tgtagccaat gttaactggc
     5581 ataataaact tttctttgag tgatattttt tagtcactaa taaaacctcc atttgtacct
     5641 gactataata atataacaat atctctttat taacaataga tttgtgaaaa attaatttta
     5701 tcatttaata ttaaaagtca gattattaaa aaatatccct accaaagcag aattaaagca
     5761 ttaatgattg tcaatatgac acctatactg gtaaaaaaag attgtgaata acgattaaaa
     5821 tagtaaaata tgagctattg ttatcagctt atccttagac attaaaaaag attgaagaaa
     5881 ccccctttct gaagctttct tcaatcctga ttctggctat aacaaataaa tcaaaacaat
     5941 cctactgctg taccgtcttc ggtgacgtcc atcttcatag ctgcaggaat ctttggcaag
     6001 cctggcattg tcatcacatc tccagttaag gcgacgataa agccggcacc ggtcttaggc
     6061 actaattcac gaatggtaat gtcaaactga tctggcgcgc ctaggagcga tggatcgtct
     6121 gaaaagctat actgggtttt ggccatgcaa acaggcaatt gatcccaacc aaactgggca
     6181 aattgcttga gctgattttt agctttaggt ccgaattgca cagccctacc accataaatt
     6241 tcagtcacaa ttgccttaag tttctcctct aagctatcct tgtctgcata tagacgctta
     6301 taggctgcgc tttcctctgt aatagccttg acaacagcgt tggcaagagc aataccgcca
     6361 tcagccccct tggcccacac gcttgccaat tcaaccggaa cagctatttc tgcacacaat
     6421 tcttttaaga cttgaatttc tgctttagta tctgtcacaa attcgttgat agctacaaca
     6481 atcggaatat tgaattttcg aatattctca acatgacgct ttaaattagc aaagccagac
     6541 cggaccgcag ctgtattttc aaaggttaaa tccgccttag caacaccgcc atgcatcttc
     6601 aaggcacgaa gtgttgcgac aataacaact gcatcaggag ccttaggtag attcggtgtt
     6661 ttgatgttaa ggaatttttc tgctccaaga tccgctccaa agcctgcctc tgtaacagta
     6721 taatctgcca accgcaaagc tgttgatgtc gccagaacag aattacagcc atgagcaata
     6781 ttggcaaagg gtccaccatg cacaaaggct ggtgtaccat agattgtttg aacaaggtta
     6841 ggcttgatgg cgtccttcaa aatcaaggct aatgcccctt ctacctttaa atcacgcaca
     6901 tatacaggtg atttatcgta acgataggca atcacaatat tagctaaacg agccttcaag
     6961 tccttaagat cagtcgccaa gcaaaggata gccatcactt cagaggctac tgtaatatca
     7021 aaaccgtctt ctcttgggac accattgaca ggactcccca agccaacaat gacctgccta
     7081 agagaacggt cattcaaatc aaggacacgc ttccagatga tacgacgcgg gtcaatacca
     7141 agctcattgc cctgctgaag gtgattatca ataagggctg ataaagcatt atgagctgtg
     7201 gtaatagcat gcatgtcccc ggtaaaatga aggttaatat cttccatcgg aagaacctga
     7261 gcgtagccgc cacctgcagc accacctttg atccccataa ccggtcctaa agagggctca
     7321 cgcaaggcca gcatggtttt tttaccgatt ttagtcaagg catctgccaa accaatagac
     7381 atggttgatt tgccttcacc tgctggcgtt ggattaatag cagtcactaa aatgagctta
     7441 ccaggcttat tgtcctctac tgatttgatt ttttcaaagg ataatttggc tttgtagtta
     7501 ccgtaaagct ccaaatcatc agcatcaatc cccacctttt taacgatttc tgtaatcggc
     7561 tttaagggga cactttgagc aatttcgata tctgatttca tgaaaactcc ttgactctta
     7621 cttgatagtg ttattatatc acacttcatc tcaaacgtac attgatttgt tctatataca
     7681 aaaatgttcg tttttataat ggttctgaaa ggaaaaaagc ttagtagcgt cagcattgtc
     7741 agtaaaaata attttaatta gtgattttat ttactattct tgctttttct gataaaatat
     7801 ggctatgaaa ttattaatca catcaggcgg aacgaccgaa gcaatagacg ccgttagagg
     7861 gattaccaat cattccactg gccagctagg aaagatagta gctgagacct ttctagcaaa
     7921 gggatttgac gttactctag tgacaacaaa aacttcagta aaaccagcac agcagcctca
     7981 tttgaccatt cgtgaggtga ccaatgttga tcagctgatg gctatcttaa aagaggaggt
     8041 tcctaagcac gaccttctca ttcacagcat ggctgtttca gattatagcc cagtgtacat
     8101 gacagacttt gatacagttg cagctgctga tcatttacag acctttttaa cagcaagcaa
     8161 taaggaagcc aaaatctcat cggcagctga ttatcaggtg ctctttctta aaaaaacacc
     8221 taaagtcata tcctatatta aggaatggaa tcctaatata aggctagtcg gctttaagct
     8281 attggtcaat gctccagctg aggagctaat ttcagtggca cgagatagcc tgcataaaaa
     8341 caaagcagac tatatagtag ccaatgacct agcagatatt aaggccaatc agcacaaggc
     8401 ttttcttgtc aatgacaaaa cagtctgctc tgccagcacc aaagaggagc ttgcacaatt
     8461 aatctatgaa aggataatag ccaatgacta agcgaataac acttgcggtc tcaggtagta
     8521 tttctgccta taaggcagct gatctcacca gccaattaac caaaaaaggc tatgaggtta
     8581 ctgtgttgat gacgcaagca gctactgcct ttatcactcc gttgacccta caggtcttat
     8641 cgaaaaatcc tgtccatcta gatgtcatgg cagagcacga tgtcaaaatt gtcaatcata
     8701 ttgagctagc taaagcaaca gatctatttg tccttgctcc tgcaagtgcc aataccattg
     8761 ctcatttagc ctacggcttt gctgataata tggttaccag tgtcgcccta gccctgcctg
     8821 aggcaacacc caaactcatc gctcctgcta tgaatactaa catgtacctt aacccaatta
     8881 ctcagggaaa catcaaacgc ttagctgatc ttggctttcg agaaatacca cctaagacag
     8941 cactccttgc ctgcggcgac agaggacctg gggccttagc agatattgat gatatggtta
     9001 cagcaattag tcagcagcta gcaagatagc tggtcaccga ttagcaattg ctgtattata
     9061 atataaaaat ttaatggaga atgcaatgaa tcataacaaa tcttctgaaa tctctcgtat
     9121 tgccatcttt tttgcagtca tgctggttat tcacttcatt agtagctggt ttttttatat
     9181 ctggcctgtc ccaattaaac caacactcgt ccatattcca gttattgttg cttctatcat
     9241 gtatggtccg cgcactggag ctatcttagg aggcttgatg gggattgtca gtgtgatcac
     9301 aaataccttg gttttacttc caacaagcca tcttttctca ccatttgtca caaatggtaa
     9361 tctggcttcc ttgatgatcg ctatgctgcc tcgtatcctg attgggatca ctccttatta
     9421 ctgttataag cttatcaaaa acgagcttgg gcttgtccta gctggtcttg ttggctcgct
     9481 gacaaacacc atttttgttc tctcaggaat atttatcttt ttcccaacag cctctggtga
     9541 caatgtcaaa acgtttctaa ctaccattgt atctggcaat gctattactg aaatgattgt
     9601 ttcagctatc gttaccatta ctcttatccc agctttatcc aagctcaaaa aatcataata
     9661 ttgctcaagc tatgaagcat gctgtctgat aaggatagca tgctttaatg atatgtgaca
     9721 agcaaggaaa ttgatcctta tgtgaaaaaa tgattggaag ctattacaga aaataagtga
     9781 tttttccttt tcaacatgat ataatcccga ctttatcact taaaaacaag taaagaccag
     9841 ctaacccctt gtgtcccaag ggattttgct ggtctttaaa tttattttag tgttgtatat
     9901 ggatttttag cgtaatgttt gagctcttca aacttaacga ttcccttcgc ccattcaatt
     9961 cctagcagtc tgtttaactc ttgcatatca aggctttctt gaagtctgta gtagttatct
    10021 tgtaacggtg ttaccttggc actgtttaag gcagtaatga tacgttcagg actcatctgc
    10081 caatctatct gatgttgaag gaggcgtaga tgaactaaag caatgaaaca ggttagaaag
    10141 tgagcttgaa tgtgtttttc cgtccaaacg taaacaggac ga
//
LOCUS       DARYYD010000065         9942 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.066, whole genome shotgun sequence.
ACCESSION   DARYYD010000065 DARYYD010000000
VERSION     DARYYD010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9942
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.066"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            13..468
                     /locus_tag="TV188_001676"
     CDS             13..468
                     /locus_tag="TV188_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEL1535007.1"
                     /translation="MEYDKLPSWKDLPDLELYLDQVLLYVNQVTQLSQATDHKLLTAS
                     MINNYVKHGYIDKPIKKKYQKKQVARLIAISILKNVFPIQDISQVLTSLQAASSSEVL
                     YDTFVNYWNNGLTQSTPEIISYACQTVKDYQHTMKLSREMEDTKHEPNL"
     gene            452..1102
                     /locus_tag="TV188_001677"
     CDS             452..1102
                     /locus_tag="TV188_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEL1535008.1"
                     /translation="MNQTFKQSLPLSVNEEVANSVTHAIGAAAMLILLPITAIYSYQT
                     YDLKAAVGASIFIISLFLMFLSSTIYHSMSYGTTHKYILRIIDHSMIYIAIAGSYTPV
                     ALSLVEGLLGYVIIILQWGITLFGILYKIFAKTINEKFSLALYIIMGWLVVFILPVII
                     QKASLPFGILMLLGGLSYTVGAGFYAKKKPYYHMIWHLFILLASALQVIAIIFYML"
     gene            1212..2116
                     /locus_tag="TV188_001678"
                     /pseudo
     CDS             1212..2116
                     /locus_tag="TV188_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515585.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            complement(2469..2744)
                     /locus_tag="TV188_001679"
     CDS             complement(2469..2744)
                     /locus_tag="TV188_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535009.1"
                     /translation="MKKSYGIGLGLLLGSAAIAVTYLSLSSAKKKELLKEGSETIEEL
                     NHYIQEKGGQLIETASDKVEASKVAANACGHSAAKAIKGTLEEAIKI"
     gene            complement(3167..4717)
                     /locus_tag="TV188_001680"
     CDS             complement(3167..4717)
                     /locus_tag="TV188_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007893974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEL1535010.1"
                     /translation="MSILEVKQLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGHLQPDAGKIEWSKYVTAGYLDQHTVLEPGQTVRDVLRTAFDELFKTEERIN
                     AIYMSMAEETADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMETEVT
                     SLSGGQRTKILLAKLLLEKPDILLLDEPTNYLDAEHIEWLKRYLQHYDNAFVLISHDI
                     PFLNDVINIVYHVDNRNLVRYSGNYDQFKEVYEMKKAQLEAAYERQQKEIAELQDFVN
                     RNKARVATRNMAMSRQKKLDKMEIIELQAEKPKPSFEFKEARTPSRFIFQTRELVIGY
                     DRPLTKDPLNLTFERHQKVAIIGANGIGKSTLLKSLLGIIQPLSGEVETGDFVELGYF
                     EQETAGVKRQTPLEAVWDAFPALNQAEVRAALARCGLTSKHIESQIQGLSGGEQAKVR
                     FCLLMNREHNVLILDEPTNHLDVDAKEELKRALQVYKGSILMVCHEPEFYEGWVTDIW
                     DFNQLTSL"
     gene            complement(5388..5948)
                     /locus_tag="TV188_001681"
     CDS             complement(5388..5948)
                     /locus_tag="TV188_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEL1535011.1"
                     /translation="MTSKRLTDQIELSLFAALIFISVELLRIPVGAQFIHLGNALVVV
                     AVLLYGARRAALVAAIGLGLFDMINGYAAVVWITVLEALVVCYLLHVIYEKLLKSVDK
                     PMIIVAIGLLAAAAKLVMNLVKYSLIAYFGAQLPLSVALWAALGKIGGSLGTALVTVI
                     AVPLLYPVFKQLRQAVKKQEASNRLG"
     gene            complement(5926..6795)
                     /locus_tag="TV188_001682"
     CDS             complement(5926..6795)
                     /locus_tag="TV188_001682"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HEL1535012.1"
                     /translation="MLKRVIVANDIVGVGKVALSASIPIMAACQIEQAILPTCLLSSH
                     TAIAKTPYIQSTSEGLKPFLTTWSQAGLAFDGFFSGYLYRPDDALIILDYIKKQQLPF
                     VLDPIMADKGSMYAQLTSQHLSAMRLLAQAAQLILPNVTEACLLADVPYFGETYSRED
                     LERLLSKLATLGPREIVLTGISFDDQHIGFAYYQKATETVSYHFGKRYPYHFYGTGDL
                     VSAIVSAGYFHRLAIDELLDMVISFLDKSLAATVALNRELSLGIAYEVELGSLGAAFR
                     GLLEEKDDIKTID"
     gene            6887..8158
                     /locus_tag="TV188_001683"
     CDS             6887..8158
                     /locus_tag="TV188_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEL1535013.1"
                     /translation="MTSKYQQIIADLELAMQSNQFKKGEKLPSIRQLSQQYHCSKDTV
                     QRALLALQYKRLIYAIPKSGYYVLGKIEEKQHSFELSLEDYNQLAYEDFRLCLNEALD
                     GKDSDLFNYYHKAEGLEELREALLPYLADNGIYANKNQLLITSGTQQALYILAQMRFP
                     NGRHHILLETPTYHRMEQLATSLGLPYQTIERDVNGINLHQLESIFKTGQIAFFYTIS
                     RFSNPLGLSYSKKEKESIVRLAEQYQVYIVEDDYLGDFASHSELPLHYYDTQHRVIYL
                     KSFSMSVFPALRIGALLLPDDLKEGFLLQKSMIDLDTNLIMQKALALYLANGMFQKNL
                     KQMRQFFNNRAHNLLDFLQKHLPNLAYQLTPQALIIQLDKAFNRKKLLKPHHTQIIST
                     RKARYMLLTISPDMPSKLLDLFSVTHEKTQE"
     gene            complement(8194..8532)
                     /locus_tag="TV188_001684"
     CDS             complement(8194..8532)
                     /locus_tag="TV188_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535014.1"
                     /translation="MQIIKRDGQLADFDPDKIYQALIKAARTVYVIDDSWRQHLAQVT
                     KKVVIDLEEVQAERPTINMIQSLVENRLIDAGYMTIAEHYIAYRLQRDLERNGYGDSI
                     SVHLRFEQIK"
     gene            complement(8632..9720)
                     /locus_tag="TV188_001685"
     CDS             complement(8632..9720)
                     /locus_tag="TV188_001685"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEL1535015.1"
                     /translation="MGYTVAVVGATGAVGQQMIKMLEESSLPISAIKLLASARSAGKI
                     LSFKGEDFVVEELTKAAFQGIDLALFSAGGNVSAKYAPYAVAAGAVVVDNTSYFRQHP
                     AVPLVVPEVNAHALDTHQGLVACPNCSTIQMMIALEPIRQRWGLERIIVSTYQAVSGA
                     GQSAIRETLAQYDQVINQGLSPKEVEASVLPSAGDKRHYPIAFNALPQIDRFTENDYT
                     YEEMKMTNETKKIMEDDTIKVSATCVRIPVLSAHSESIYIETKAVATIEAVKEAIAQF
                     PGAVLEDDTGVQRYPQAVNAVGSRETFVGRLRKDLDVEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPAQDNLFDPSVSFD"
BASE COUNT         3010 a         2233 c         1794 g         2905 t
ORIGIN      
        1 gaggttttag taatggaata tgataagctg cccagctgga aggatttacc tgatttggag
       61 ttatacttag atcaagtgtt actctatgtc aatcaggtca cacaattgag tcaagccaca
      121 gaccataagc tactgactgc ttcaatgatc aataactatg tcaaacatgg ctatattgat
      181 aaacctatta agaaaaaata tcaaaaaaag caggttgccc gcttaattgc tattagcatt
      241 ttgaaaaatg tatttcctat tcaagatatt agtcaggtct tgacgagcct acaagcagcc
      301 tccagctcag aggtcttgta cgataccttt gtcaactatt ggaataatgg ccttacccaa
      361 tcaacgcctg aaattattag ctatgcttgt caaaccgtca aggactatca gcacacaatg
      421 aagctttcaa gagaaatgga ggataccaag catgaaccaa acctttaaac aaagtctccc
      481 actatcagtt aatgaagagg tcgcaaatag tgtgacacac gctattggag cagctgctat
      541 gctgatactg ctacccatca ctgctattta ctcttaccag acttatgatc tcaaggctgc
      601 cgttggagca tctattttta tcatcagctt atttctcatg tttttatcat caacgattta
      661 ccattccatg tcctatggaa caactcacaa atacatttta cgtatcattg atcatagcat
      721 gatttatatt gctattgctg gtagctatac acctgttgcc ttatccttgg ttgagggctt
      781 gttgggctat gtgattatca tactccagtg gggaatcaca ctttttggga ttttgtataa
      841 aatttttgct aaaacgatta atgaaaagtt cagtcttgcg ctttacatta ttatgggctg
      901 gttggtcgtt tttatcctgc cggtgattat ccaaaaggcc agtctgccat ttggaatctt
      961 gatgctacta ggtggcttat cctatactgt cggcgcaggc ttttatgcta aaaagaagcc
     1021 ctattatcac atgatctggc acctttttat ccttttagcc tctgctttac aggttattgc
     1081 cattattttc tatatgctgt aaaaagtagc tgttgctact ttttaaacgc gagcgcttgc
     1141 ttacccccag acacctggct tgattcatgc tataataaag ggcagtaaat agttgaaggg
     1201 atcaaagcaa tatgaaaacg gtacatattt tttacaatcc taattcagga aaaccagaaa
     1261 atgacctggc tgaaaaggtc aagcattatc tgattcaaaa tggtttttct gaagacaagg
     1321 ttcagattat tacccccaaa aatgctgatc aagcctttca attagccaaa aaatcctcac
     1381 aggatcatat tgatctagtc attcctctag gcggagatgg gacacttaat aaaattattg
     1441 gaggtgttta tgaaggtggt gctcattctg ttattggact cgtaccgtcg ggcactgtca
     1501 ataactttgc aaaggcctta aacattccac tccagctaac tgaggcactt gagacgattt
     1561 tatctggcac gattaaaaaa gtagatattt gcaaggtaaa caagggctat atgatttcta
     1621 gcctaacctt gggtctgctt gctgatattg cggctaatgt gactacagaa gaaaaacgaa
     1681 aatttggccc ttggcctttt taaaggatag tattaagata ctaaaacgaa accgcacata
     1741 tgcaattagc ttaattagcc atcatcatgt tcttcacttg aaaaccaaat tcttattgat
     1801 taccacaacc aatactatag caggtcttcc atcgttttca ccaggtgcac aagctgacga
     1861 tggcttgtgt caagtttaca cgatgagcca gctatcattt ctgaaatgct tgcgccatat
     1921 tagagacttt agacgggggg atttttccaa ggtaaaggag attagccatt ttcaagctga
     1981 ttctctaaag ctattgccac aatatcagcg tcaatcagcc attcctagaa ctcgcattga
     2041 tggcgataag gctgatgatc tccctgttga attgaaggtt attccaaaag cgatttccat
     2101 tattgttagc cagtaaaaaa gtgccctagg gcactttttg atatagattc atctccaagc
     2161 tgagttttag aaaactaagc tatagctata acgttagctg tggcttcttc ttgctggctt
     2221 gcagtactct tttcttgtct taacagctag ctctttcata atatcggctt taacaaagaa
     2281 gctatctgac tagtccgatc ttctattctc aggacaaaca gcgagaaagg ggattttctt
     2341 tgaatcctag agaaccttag ctatctctgt gtctcattgt aagtgcagct ctattgactg
     2401 atgccagcta tagcaataag cccagtcgca tattataaag gattatcagg cgatttagct
     2461 tgacactctt atatctttat tgcttcttct aaggttcctt taatagcttt agctgctgaa
     2521 tgaccacagg cattagcagc aaccttagag gcttctacct tatcagaggc tgtctcaata
     2581 agttgtccac ccttttcttg gatataatgg ttcaactcct caatagtttc agagccttcc
     2641 tttaagagct ctttcttttt ggctgaggat aagcttaaat atgtcacagc aattgctgct
     2701 gaaccaagaa gtaatcctaa gccgattcca tagctttttt tcatcatcaa ccctactttc
     2761 tatgaccttc cttaatcatc tttttagcta attttacagc tggtactact aaaagcacca
     2821 attgtaaaag atccatatac ttgatttttc gtcgtttttt caccatgtgc tatttccttt
     2881 ttcttgtttg caccatacaa tcgtctttta ttgcgcagtg ccagagactg cctgattagg
     2941 cagcgtaagc taagaactat cagcgtgtca gactagtcta gatacagcta agcactagct
     3001 tgattacgat aatacttacc gctaggccat aagctcagct atcatcaaat ctaaagtgac
     3061 aacgcttttt atttattata ttgtcatttt actaaaatac acaattatcg tcaatgcttt
     3121 tgctttaggc agcaaaaatg cccaagataa agaccttgga catctgctac aatgacgtta
     3181 attgattgaa atcccaaata tcagttaccc agccctcata aaactccggc tcatggcaaa
     3241 ccatcaaaat agagccttta tagacttgca aggcgcgttt taactcctcc ttagcatcta
     3301 catctaaatg attggttggc tcatctagga ttaaaacatt gtgctcacga ttcattaaga
     3361 gacaaaaacg aaccttggct tgctcaccac ccgagagccc ctgaatctgg ctttcaatat
     3421 gcttagaggt tagaccgcaa cgagctaagg ctgcccgaac ctctgcttga tttaaagcag
     3481 gaaaagcgtc ccatactgct tctagtggcg tttgacgctt aacacctgca gtttcttgct
     3541 caaaataacc aagctccacg aaatctcctg tttccacctc tcctgacagt ggctgaataa
     3601 tgccaagcag gctctttagg agggttgact taccaatacc attagcaccg ataattgcaa
     3661 ctttttgatg acgctcaaat gttaagttca agggatcttt tgttaggggt ctgtcatagc
     3721 cgatgacaag ctcccttgtt tggaaaataa agcggcttgg tgttcttgct tccttaaact
     3781 caaagcttgg ctttggtttt tctgcctgaa gctcaatgat ttccatttta tcaagcttct
     3841 tttgacggga catagccata ttgcgagtag ctactctggc cttattacga ttgacaaaat
     3901 cctgtagctc tgcaatctct ttttgctgac gctcataggc tgcctctagc tgagcttttt
     3961 tcatctcata gacttcctta aactgatcgt aatttccaga atacctaacc aaattccgat
     4021 tatcaacatg ataaacaata ttaatgacat catttaaaaa aggaatatca tgtgaaatga
     4081 gcacaaaggc attgtcataa tgctgtaaat agcgctttaa ccactcaata tgctcagcat
     4141 caagataatt ggtcggctcg tccagcagca aaatatctgg cttctccagt aacagcttgg
     4201 ccagcagaat cttggttctt tgccctccag ataaggaggt cacttctgtt tccatcccaa
     4261 aatccataac tcctaaggca cgcgcaacct catcaatctt agcatctagg gtataaaagt
     4321 ccctgctttc aagacggtcc tgtagctctc cgacctcctc cattaaggcg tcgacatcag
     4381 ctgtctcctc tgccatagac atgtaaatgg cattgatacg ctcctctgtt ttgaatagct
     4441 catcaaaggc tgtcctaaga acatcacgca cagtttgacc aggttctaaa acggtatgct
     4501 gatccaaata gcctgctgta acatactttg accattcaat cttaccagca tcaggctgca
     4561 agtgaccagt aacaatactc ataaaggtgg acttgccttc tccatttgct cctactaatc
     4621 caatatgctc gccctttaaa agacgaaagg aaacatcttc aaaaatggca cgatcaccaa
     4681 atccatgact taactgctta acttctaata tgctcatgat tactttcctt tattgtcatc
     4741 aaaaaagccg ttaaaacggc ttacactctc tcaattatgg caaaaatgca gccttttgtc
     4801 aatgaaggct gaaaaagcct acgtcatacg catgaaagat ttttagcaag aacagaaggt
     4861 tttttgcatt ttaatgttca gctatttcaa atatgtctta ttattttata aattttacta
     4921 tagggaaagc cttgaaagtg cctgctttaa tttatactat cattcggaaa gaactgtttc
     4981 gctcgtttgt tgtggaaagc cgctcacaac aaagacatag agagtctatg acaacaagag
     5041 ctacacttta gcaagtcttg accgacatgc tttattgccc agtctaattc attaaaaagc
     5101 gaacaggtct agctttcgga atttcagaaa actaggcctg ttcatttgtt ctattttgag
     5161 gcagcctttt gtttcggcct cgtctgtttc aaggttttca gatcgaactt aaggacaaaa
     5221 aacactctcc tgtatcagct aaccttatca ttcattataa aggaaaatga tttctaatac
     5281 aaggaaatac cgttatttca ttaaaaataa ctaaaaatag tttgtcaaat cattagttat
     5341 taataggctt agataacaaa aatgatgata ctgctagcaa ggttagctca accaagccta
     5401 ttactcgctt cttgcttttt tactgcctgc cttaattgct taaaaacagg gtataagaga
     5461 ggcacagcaa taacggtcac aagggcagta ccaagactgc caccaatttt gccaagtgct
     5521 gcccacaaag caacagacag gggtaactgg gcgccaaaat aagcaatcaa gctatatttc
     5581 acaagattca tgactaattt tgctgctgct gctaataagc caattgctac aataatcatc
     5641 ggtttatcaa ctgatttcag aagtttctca taaatcacat gaagcaggta acaaaccact
     5701 aaggcttcaa gcactgttat ccagaccaca gccgcatagc cattaatcat atcaaacagt
     5761 cctagaccaa tggctgccac caaagctgcc cttctagcac catacaataa aacagccacc
     5821 accactaagg cattccctag gtgaataaat tgggctccaa ctggaatacg cagcagctca
     5881 accgatataa aaataagagc agcaaatagg ctaagctcga tctgatcagt caatcgtttt
     5941 gatgtcatct ttttcctcca ataatcctct aaacgcggct cccaagctgc ccaattctac
     6001 ttcgtaggca attccaagtg aaagctctcg atttagcgca acagtagccg ctaatgactt
     6061 gtctaagaag ctaataacca tatccaacaa ctcatcaata gcaagcctgt gaaaataccc
     6121 agcgctaaca atagcagaga caagatcacc tgtcccatag aaatgataag ggtaccgttt
     6181 tccaaaatga tagctaaccg tctctgttgc cttttgataa taagcaaagc cgatgtgctg
     6241 atcatcaaag gatataccag taaggacaat ctctctaggt cctagtgtag ctagcttaga
     6301 caatagcctc tccaaatcct ctctgctata ggtctcccca aaataaggaa catcagctaa
     6361 caaacaagct tccgtcacat ttggcaatat cagctgtgca gcttgagcga gcaatctcat
     6421 tgccgataag tgctgcgagg ttaactgcgc atacatgctt cccttgtcag ccataatagg
     6481 atctagcaca aagggaagct gttgcttttt gatgtaatca agaataatca aagcatcatc
     6541 aggacggtac aaataaccgg aaaaaaagcc atcaaaggca agacccgctt gagaccaagt
     6601 cgtcaaaaat ggctttagtc cctctgacgt gctctgaata taaggcgtct tagcaattgc
     6661 agtgtggctt gataacaaac aggttggaag aatggcctgt tcaatctggc aagccgccat
     6721 aatgggaata ctagcagaca gagcaacctt gccaactccg acaatatcat ttgcaacaat
     6781 aacacgtttt aacaaccaat aagctccttc atttcttttt ttactattgt aagaaaatcc
     6841 ttgatgagat acaataagga tagatttcat ctgtatgggg acacttatga caagtaaata
     6901 tcaacaaatc attgcagacc tagagttggc catgcaatca aaccaattca aaaagggaga
     6961 gaaactccct tctattagac aattaagtca acagtatcac tgcagcaagg atacagtgca
     7021 aagagcactt ttagccttac aatacaagcg cctcatttat gctattccaa aaagtggcta
     7081 ttatgtgctt ggtaaaattg aggaaaagca gcattccttt gagctaagcc ttgaggatta
     7141 taatcagttg gcctatgagg actttcggct ctgtctaaat gaagccctag acggtaaaga
     7201 ttctgattta tttaactact atcataaggc tgagggactt gaggagctgc gagaggcttt
     7261 gctgccttat ttggctgata atgggattta cgctaacaaa aatcagctgc taattacctc
     7321 gggtacacaa caggcccttt acattttagc tcaaatgaga tttcccaatg gccgccatca
     7381 cattctcctt gagacaccga cctatcaccg aatggagcag ctagcgactt ccttaggctt
     7441 accctatcaa accattgaac gtgatgtcaa cggtatcaat cttcatcagc ttgaaagcat
     7501 ctttaaaacc ggacaaatcg cttttttcta tactatttct cgattttcaa accctcttgg
     7561 cctctcctac agcaaaaaag aaaaggaaag cattgttcgg ctggcagagc aataccaggt
     7621 ttacatcgta gaggacgatt atctagggga ctttgcatcg catagtgagc ttccgctaca
     7681 ctactacgac actcaacacc gggtcattta tctgaaatca ttttcaatga gcgtctttcc
     7741 tgccctgcgc attggagcct tgcttttacc tgatgatctc aaggaaggct ttttgttaca
     7801 aaagtcaatg attgaccttg ataccaacct gatcatgcaa aaggcactag cattatattt
     7861 agcaaatggt atgtttcaaa aaaacctaaa gcaaatgagg caatttttca acaatagagc
     7921 gcataactta ctagattttc tacaaaaaca ccttcctaac ctagcttatc agctcactcc
     7981 tcaagcactg attattcaat tagataaagc attcaatcgc aaaaagcttc ttaaaccaca
     8041 ccacacccaa atcatctcaa caagaaaagc aaggtatatg cttctaacaa tcagtcctga
     8101 tatgccatct aagctgctcg acttgttttc agtgacacat gaaaagaccc aagaatagct
     8161 cattgggtct cagtgtcaca aaaatgtcaa tagctatttg atttgctcga atcgtaaatg
     8221 aacactaatg ctatcgccgt aaccgtttct ctccaaatct ctttggagcc ggtaagcaat
     8281 ataatgctct gcaatagtca tgtagcctgc gtcaatcaga cgattttcaa caagtgattg
     8341 aatcatatta atcgtcggac gctccgcctg cacctcttct agatcaataa caaccttttt
     8401 agttacctga gctagatgct gtctccagct gtcatcaatc acataaactg ttcttgctgc
     8461 cttgatcaaa gcctgataaa tcttatccgg atcaaagtct gccagctgac cgtcacgctt
     8521 aataatttgc ataagagcgc ctcttttcat ttagtttcat tgcttacatt cattatgcaa
     8581 atgttttcat catttgtcaa gctattaggc tcctatgcct cttagggatt atcagtcaaa
     8641 agaaacacta ggatcaaata aattgtcctg tgctggtcgg acaagcccac gctcgtgcaa
     8701 ggtctctgca atctgaacag aattccaggc tgcgcccttg agcagattgt cagataccac
     8761 ccacatgtga atgccctttt caacatctaa atccttacga agccttccta caaaggtctc
     8821 acgactgcca acagcattaa cggcctgtgg gtatcgttgc actccggtat cgtcctctaa
     8881 aacagcaccc ggaaattgtg caatcgcctc cttaacagct tcgatagtag ctactgcctt
     8941 ggtttcaatg tagatagatt ctgaatgggc tgataaaacg ggtatacgaa cacaggtcgc
     9001 agacacctta atcgtatcgt cctccatgat ttttttcgtt tcatttgtca ttttcatctc
     9061 ttcataggtg tagtcatttt cagtgaaacg atcaatctgt ggtaaagcat taaaagcaat
     9121 tggataatgt ctcttgtcac cagctgacgg taaaacactt gcctccacct ccttaggaga
     9181 caagccctgg ttaataacct ggtcatactg agctagggtc tcacgaatcg ctgattgacc
     9241 agcacctgaa acagcctgat aggtggaaac aataatacgc tcaagacccc acctttgacg
     9301 aataggctcc agcgctatca tcatttgaat cgtagagcaa ttagggcaag caacaaggcc
     9361 ttgatgtgta tcaagagcgt gagcatttac ctcaggaaca acaagtggaa cagctgggtg
     9421 ctgacgaaaa taagaggtat tgtcaaccac aacagcacct gccgcaacag cataaggggc
     9481 atattttgca gaaacattgc ctcctgctga aaaaagggct agatcaatgc cttggaaggc
     9541 tgcttttgtt agctcctcaa caacaaaatc ctctccctta aatgagagga tttttcctgc
     9601 tgaacgtgca gacgctaata atttaatagc tgaaataggc agacttgact cctccagcat
     9661 cttaatcatt tgctgaccga cagcgcctgt cgctccaacc actgctactg tataccccat
     9721 agatcgacct cactttaact gatgatattg caaaaaatga tattggacct attatagcct
     9781 atttcatcac aaaagaaaag caagctagaa gccagaacaa acgcatgaag aaaatcattt
     9841 attgaaaaag ttgtgaaaat agcaaaatat ccattttaga gtattttgac agagtgtttc
     9901 ctgaattttt atatttttcc tctataaact tttcttgaaa aa
//
LOCUS       DARYYD010000066         9565 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.067, whole genome shotgun sequence.
ACCESSION   DARYYD010000066 DARYYD010000000
VERSION     DARYYD010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9565
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.067"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(116..538)
                     /locus_tag="TV188_001686"
     CDS             complement(116..538)
                     /locus_tag="TV188_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535016.1"
                     /translation="MEHSQLEWEDVSQYEEVKGYGQQVWKRQGTYYLVTNEGGIAEQR
                     VVYELPYDLFELLEQGKRNLGEIAFKLRYDCWPPTEEEKIASDKAFLQRSPIALIADP
                     TSWELFTQEELRKLIPIAEQKWIDWKGKLPDDYVSPLK"
     gene            complement(861..1121)
                     /locus_tag="TV188_001687"
     CDS             complement(861..1121)
                     /locus_tag="TV188_001687"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535017.1"
                     /translation="MDNNNCFQYTQRLRELIELEYPKQKNYSGILRDLYVLTNDIDNN
                     RIVGNINFSSLARQFVDDTTQYDSPILKTLKDLEVCLNRKRR"
     gene            complement(1136..2944)
                     /locus_tag="TV188_001688"
     CDS             complement(1136..2944)
                     /locus_tag="TV188_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535018.1"
                     /translation="MSYNIKYDEITSLQQSTQTTISAWGDGITSIQTALSALIGDSRL
                     QGQTASSIKSYLSEVHGTLLQTLQSLMNDYSASLLLYKDGYYQIDSNSHAQLPGQVFK
                     TLQSELRLSQAHLKDQLELLQNTRAKLSDLVHYSGVSHAKTVVDYSELITDIHRLDEA
                     IIQYESNHASQDLAAFKELLASTKALIAEYSSKPKRAGSYQVGDIGQLNTIKRFATAY
                     QGVARHLETNAKRLQAAQERDHARFEAVAAEDRAKQGWIDLALSLVTIAVGVAAIVMT
                     AGAATPLVVGAFVVGSGTVAYGASNLYEAGHNIYLGSVGDGLTVATNPLRDTLFMGND
                     RLYHQIGGLFTTASAALILIGQTKSVAKGLTEFTIGEVGGFIGGQASYHGTKLLGGSE
                     QDAQRATLVGNILAGYAASSAARRFSLNEPIAARVTKPTYNHQQLLKNLENSRLARES
                     SNFGGYIKKESVTKYPTQIDSKVTVGAKENLPGWIADSFTDSHYRTVITGEEITLYRT
                     FGGASDAGGGFVTTVPATNRIQAKIDTALLPEWKNTRQYEAVIKIPKGSQLNIGKVAP
                     QTVKSSGTTLIGGGDQVLLPNRWPLEWIQEIRIVPN"
     gene            complement(3585..4484)
                     /locus_tag="TV188_001689"
     CDS             complement(3585..4484)
                     /locus_tag="TV188_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEL1535019.1"
                     /translation="MVLFTGKTVEEAIEKGLQELGLSRLKAHIKVISKEKKGFLGFGK
                     KPAQVDIEGINEKTVYKADKKAVRSVPEEINRQNAPVINPDEVELEEMKAVRSQDRRA
                     AESDAHQPTGPLSTAQSAPTQSKAQPVSSAAGASQLDPAAADMSKDIELAAQEISDYV
                     TKIIYEMDIEASIERTNNRRQINLQIETPEAGRVIGYHGKVLKSLQLLAQNFLHDRYS
                     KNFSVSLNVHDYVEHRTETLIDFTKKVSKRVLESGQDYTMDPMSNSERKIVHKTVSAI
                     DGVESYSEGNDPNRYVVVSLIHD"
     gene            complement(4496..5305)
                     /locus_tag="TV188_001690"
     CDS             complement(4496..5305)
                     /locus_tag="TV188_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002267318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEL1535020.1"
                     /translation="MKKRVKTAALVPLVLLLVACGRGEVTAQSSSSWEQLVYFFAKAI
                     QWLSFDGSTGIGIILFTIMIRLLLLPLFNMQIKSGQKMQDIQPELKALQKKYAAKDTA
                     TRMKLAEESQALYKKYGVNPYMSLLPLLIQMPVMFALFQSLTRVAFLREGTFLWVELA
                     RHDHLFILPILAAVFTFLSTWLTNLAAREKTAMITIMTYVMPVFIFFMGFNLASGVVL
                     YWAVSNAFQVVQLLLFNNPFKVIAERQRLADEEKERRAKERRARKRAMKRK"
     gene            complement(5289..5648)
                     /gene="rnpA"
                     /locus_tag="TV188_001691"
     CDS             complement(5289..5648)
                     /gene="rnpA"
                     /locus_tag="TV188_001691"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEL1535021.1"
                     /translation="MKKSYRVKREKDFQAIFKLGQSMANRKFVIYHLKGEHKHFRAGI
                     SVGKKLGNAVTRNAVKRKIRHVLMELGDHLKSEDFVVIARRGAEELDYQAVKQNLHHV
                     LKLAKLLEEGFEIEKKS"
     gene            complement(6140..6880)
                     /locus_tag="TV188_001692"
     CDS             complement(6140..6880)
                     /locus_tag="TV188_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1535022.1"
                     /translation="MLNIFILEDNLIQQSRIEAIVASILEEGRIPHNQLEVFSNPQKL
                     FDSIQERGDHQLYFLDIEIGDKSRSGLELASDIRQKDPNAVLVFVTTHSEFAPISFRY
                     KVSALDFIDKAVDSQQFKERIEECIRYTYEMMSSRQVEEMFLFETPQTRLKLPYKDIL
                     YFATATTPHKVCLWTQTERLEFYGNLSEIHAVAPKLFLCHRSYLVNLDNVVRIDKAKQ
                     LVYFENGDSCMVSRLRMKQLFEKWKSFR"
     gene            complement(6884..8182)
                     /locus_tag="TV188_001693"
     CDS             complement(6884..8182)
                     /locus_tag="TV188_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1535023.1"
                     /translation="MLGMSFFYALIFVNSWVIFSTFSGIKLAVRSLLLVGACFVVANL
                     LLDHVLLVDQLVFVAVSVGFAPHKKASEHLFNGLFAIMIVELLFRIIGSFLLPAVLGY
                     SIHQINNDIGLLMVCHALVLPAFYLFSYIFSVDLTLIKFISEDKLKKWVFWMNAALLF
                     YYVMVHCMINIQGDFFKIYFRYRSVMIFLYLMLLIWVIVKLDRFAKDQLSQRLALAQK
                     ERVAYLEKHNQYIERLCREIRAIKHDSENILISLKDSIDSGDIAAISKVYQTVIQESA
                     SSIRQLTPELSALDNVQDSVIRSLLHAKLLEAKLQGIAVYIDIPETLASSSVRLLDVI
                     VLFKVVIDNAILSAKGSSRPFLSIAYFNQDGKRFFIIENSTRLKRVDIAKQFDASRLE
                     LGSHAHKRLLQFSAVLERYPHITFSTKSDHYRLRQLLEMR"
     gene            complement(8194..9540)
                     /locus_tag="TV188_001694"
     CDS             complement(8194..9540)
                     /locus_tag="TV188_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1535024.1"
                     /translation="MTDIYYLFLLLSLMIYYVTEISIFSFLSDIKLALWKQIFVLTAA
                     LFLNQFALLPPLIIDPLLLLAVLALEKRPCFSLKALFLAFVPGVFVDLLSRFILAIVL
                     PYIFSVNGSYVRHLVLDFIAYVMIFPSFALINYFVGKDYKQIVKADRFDKASSFYSLF
                     LLFSLAYYIDLFMILGFTDPFLDLKSPIMMSTSYKVLFLIFTLLLIYLLSYFNHQSKE
                     FLKQELKKEQQAYIANLETYGKHLEKLYKGVKVFQLVYLKRLERLGQAIDSGSVSDVQ
                     TVYAQTVDEATDYWDDKHYNISKLSKISVSSIKSLLSSKIIKAEKAGIALSLEVPDRI
                     RDSYISELDLLLLVSIFCDNAIEAALETAQPAVAIAYFLSDDQQIFTVTNTTKDERVM
                     ISRIFEEGYSSKGSGRGIGLSNAKRILQKYPELSLRTRSHDYQFSQTLIMPKIEKE"
BASE COUNT         2917 a         2219 c         1709 g         2720 t
ORIGIN      
        1 acgcttggca ttggcttcaa ggtgacgagc tactccctga taagctgtcg caggctaatt
       61 attaagaaca tgctttaaaa tagcagagct aatctcggct ccgctatctt aaacattatt
      121 tcaaaggact gacataatca tctggcagtt ttcccttcca atctatccat ttttgctctg
      181 cgattggaat cagttttctt agctcttctt gggtaaaaag ttcccaactt gttggatctg
      241 caattaaggc tattggggat ctttgtaaaa atgctttatc actagctatt ttctcttctt
      301 ccgttggtgg ccaacaatca tatcgcaatt taaaagcaat ctcccctaaa ttccgttttc
      361 cttgctccaa taattcaaat aaatcatacg gcagctcata tactactcgc tgctcagcta
      421 taccaccttc attagtcact agatagtaag ttccctgacg cttccacacc tgttgaccat
      481 aacccttgac ttcctcatat tgactaacat cttcccactc taattgacta tgttccatgt
      541 atgttctcct ttacttgtac tgatatcttt cataactccc tctggcatat cacccggata
      601 agtacgacct ccaggtcgcc accagctatt agcacccttt tcattaccac ttggaataga
      661 aatccctttc tccgaaacaa cctctggtga aacatctaag cgatagagcg gatcattgcc
      721 aagataaccc tcgtcgaagc cgagtaagct ttcataaaag attgatgcat agtcagctta
      781 ctcttgttcc tcctttcttc agttttttat cataatttca tcttaaaatt taatcaattc
      841 gagcaatcta atctcactca tcatctcctt ttcctattta ggcatacttc taagtccttc
      901 aaagttttta aaattggact atcatactgt gttgtatcat caacaaattg tctagctaaa
      961 cttgaaaaat taatattccc aacaatccga ttattatcaa tatcattagt caaaacataa
     1021 agatctctta atattcctga atagtttttt tgcttgggat actcaagttc tattaactct
     1081 ctaagccttt gtgtatattg aaaacagtta ttattatcca taaatttctc cttttttagt
     1141 taggaacgat ccttatttct tgaatccact ccaatggcca ccgattggga agtaagacct
     1201 gatctccacc tccaattaag gttgttcctg aagatttaac cgtctgtggg gcaaccttgc
     1261 caatattcaa ttgactcccc tttggtattt taattacagc ctcatattgt ctagtatttt
     1321 tccattctgg aagtaaagct gtatctattt ttgcttgtat acgattagtt gcaggcaccg
     1381 ttgtgacaaa accgcctcca gcatctgacg cccctccaaa agtcctataa agtgttattt
     1441 cctcacctgt aataactgtt ctatagtgac tatctgtaaa tgaatctgca atccaaccag
     1501 gaagattttc cttagcccca actgttactt tactatctat ttgagttgga tattttgtaa
     1561 cactttcttt ttttatatag cctccgaaat tagaactctc tctcgccagc ctgctgttct
     1621 caaggttctt caaaagctgc tggtgattgt aggtcggttt cgtcactcta gctgctattg
     1681 gctcattcaa gctgaacctt ctggcggcac ttgaggcggc atagcctgct aggatattcc
     1741 ctaccaaggt agctctttgg gcatcttgct cactgccgcc taagagcttg gtgccatgat
     1801 agctggcctg accaccgata aagccgccaa cctcaccgat cgtaaactct gtcaagccct
     1861 tggcaacact cttggtctga ccaatcagaa ttagtgctgc actggctgtt gtgaacagcc
     1921 cgccgatctg gtgataaagc ctgtcattcc ccatgaacaa ggtatcccga aggggattgg
     1981 tagccactgt aagcccatcg ccaacgctac ctagataaat gttgtgccca gcctcataca
     2041 ggttcgacgc cccataagca actgtaccac tgccaacaac aaaggcccca accaccaagg
     2101 gagtcgctgc ccctgctgtc atgacgatag ccgcaacccc aaccgctatt gtcacaaggc
     2161 tgagtgctag atctatccag ccctgcttgg ccctgtcctc tgcagctact gcctcaaaac
     2221 gggcatgatc ccgctcctgc gctgcttgga gacgcttggc attggtctca agatgacgag
     2281 ccaccccctg ataagctgtc gcaaagcgtt ttatggtgtt gagctgtcct atatccccaa
     2341 cctgatagct cccagcccgc ttgggcttac tgctgtactc tgctatcaag gccttggtcg
     2401 aagccaaaag ctccttgaag gcggccaagt cctgactggc atgattgctt tcgtattgaa
     2461 tgatggcctc gtccaagcga tggatatcag tgatcagctc actataatcc actactgtct
     2521 tggcatgact gacaccagag tagtgaacca ggtctgataa cttagctctg gtattctgta
     2581 gtagctcaag ctgatccttg aggtgggcct gcgagagccg aagctctgac tgcagggtct
     2641 taaagacctg accgggtaac tgggcatgac tattactgtc tatctggtaa tagccgtcct
     2701 tatacagcaa gaggctagct gagtaatcat tcatcaggct ttgcagggtt tgtaaaagtg
     2761 tcccatgcac ctcactcaga tagctcttga ttgagctagc ggtctgaccc tgaaggcgac
     2821 tgtctccaat caaggctgac agggcggtct ggatactcgt tatcccatct ccccaagcac
     2881 tgatcgtggt ttgggtgctt tgttgaaggg aggtaatctc atcatatttg atattatagc
     2941 tcatttcttc ccctaacgtt ttcaatgcga tatcaaaatg tttcaccaat aatagcaata
     3001 catttcttta atatacctct tttattatat caaaaaaaac ttaatgatta tcacaccaag
     3061 ctaagagcat tgatgggtaa taacatatag cttatccaac cttgttagca ggagtattac
     3121 aaataatgta ttgccaagag gaaaagctga tataaatagg tgggacaaac gtggtcaaga
     3181 aaacctttaa caccaagaaa accatgataa ttcttgataa catcaaatag tgcctcagct
     3241 aaatgattat gatgaccttt accaaatcat tctttattat ctgcaagaaa agaacagtga
     3301 catctcttcg atccgattac gaatataaat caagcttcaa aaccgctctt agtaccttta
     3361 ttcgttgcca aaaatatctc attgaactct cttattcaaa cgctaagcta gaagcaacca
     3421 ataaactgag caaaaacata aagcggcaag ctttggcttt aggaacttca aagctaagat
     3481 tcccaatact tttaacatca caaaagagag caccaagctg gtcctctcta gatattagtt
     3541 attagtcacc ccactacagt tgacattgag cctctttgat gacactagtc gtgaattagt
     3601 gagacaacaa catagcgatt agggtcgttg ccctctgaat agctctcaac cccatcaata
     3661 gcagaaactg ttttatgaac aatctttcgc tcgctgttac tcataggatc catggtataa
     3721 tcttgaccag actcaagcac acgcttggat acctttttgg taaagtcaat cagggtttct
     3781 gtccgatgct ctacataatc atgaacattc aaggagacag aaaaattctt agaatagcgg
     3841 tcatgtaaga aattttgggc cagcaattgc agtgatttca aaaccttacc atgatagcca
     3901 ataacacgac ctgcctctgg tgtctctatc tgaagattga tctgacgacg attgttggtc
     3961 ctctcaatag aggcttcaat atccatctca tagataatct tggtcacata gtcagaaatc
     4021 tcctgtgcag ctagctcaat atccttactc atgtccgctg cagctggatc cagctgactc
     4081 gcaccagcag ctgacgacac aggctgtgcc tttgactgag taggagctga ctgagctgtg
     4141 cttaatggac ctgttggctg atgagcatca gactcagcag cccttctgtc ttgtgatcga
     4201 acagccttca tctcctcaag ctccacctca tcggggttaa taaccggtgc attttgacgg
     4261 ttgatctcct ctggaacact acgtacggct tttttatcag ccttatagac tgttttttca
     4321 ttaatgcctt caatatcaac ctgagctggc tttttaccaa agcccaaaaa gccctttttc
     4381 tcctttgaaa tcaccttgat gtgtgctttt agacgtgaca accccaactc ttgaagtcct
     4441 ttttcaattg cttcttcaac agtcttacct gtaaacaata ccatatccta aactcctatt
     4501 ttcttttcat tgctctctta cgagcgcgac gttccttagc tcgacgctct ttttcttcat
     4561 ctgctaaacg ttgcctttcg gcaataacct taaagggatt attaaacagc aagagctgaa
     4621 caacctgaaa ggcattggaa actgcccaat aaagcaccac accactggcc agattaaagc
     4681 ccataaagaa gatgaacaca ggcatcacgt aggtcatgat cgttatcatg gccgtctttt
     4741 ctctagccgc tagattggtt agccatgttg ataaaaaggt aaagacagcc gctaaaatag
     4801 gcagaataaa gagatgatca tgtcgcgcca gctcaaccca taaaaaggtg ccttctctta
     4861 agaaagccac acgagtcaga gactgaaaca aggcaaacat caccggcatc tgaatcagca
     4921 agggcaaaag gctcatgtaa ggattgacac catacttttt gtacagagct tgactttctt
     4981 cagctagctt catacgagtt gctgtgtctt tagcagcata ttttttttgc agggccttta
     5041 gctctggttg aatgtcctgc attttctgcc ctgacttgat ttgcatgtta aacaatggca
     5101 gtaaaagcaa gcgaatcatt atcgtaaata ggataatccc aatcccagtc gatccatcaa
     5161 aggacaacca ttggatcgcc ttggcaaaaa aataaaccaa ttgctcccag ctactagatg
     5221 attgtgctgt cacctctcca cgcccacagg ctactagtag caagacaagc ggcactaggg
     5281 ctgctgtttt aactcttttt ttcaatctca aaaccttcct caagcaattt tgctagcttt
     5341 aaaacatgat gtaaattttg tttgactgct tgataatcta attcctctgc acctctccta
     5401 gcaataacaa cgaaatcctc agacttgagg tgatcaccca gctccattaa aacatgtcgt
     5461 atcttgcgct ttaccgcatt tcgagtaaca gcatttccta gctttttgcc aacagaaatc
     5521 cctgctcgaa aatgcttgtg ctcccctttc aaatggtaaa tgacaaattt tcgatttgcc
     5581 atgctctgac caagcttaaa aatcgcctgg aaatctttct ctcgcttgac acgatagctt
     5641 ttcttcaaaa cttaactccc atatctaaat tattaccatt ataccataaa acattaaaaa
     5701 gcctcaaccc ttatcaatgg gcctataata agagattgga cccactatct aaaggatcag
     5761 aacaaaaaat gcttttagtg aatcacggta gctgtcaagt cttgatagcc ttatcaatca
     5821 tactagcaaa gaaacaaaaa aataaagccc ggtaaaccga gctttatctc cgctgacttg
     5881 agcatcagca aatatgatat ccaaacaaag acaactgaaa caatcatttt aataacaagc
     5941 agccatatca aaaatactat ttgtttatgg agagagagag aaaacaatat tttgattgaa
     6001 ttggggatgg accactccat tacctaatga tttcgtaaat ctttattcat actagacatt
     6061 atagcgaaaa atcactaaaa aagatgacaa tttcctgaaa tgttcatttt tcgtcctaaa
     6121 atgtcattca acttaatttt tagcgaaaag acttccactt ttcaaaaagc tgtttcattc
     6181 tcaaacgaga gaccatacaa gaatcaccat tttcaaaata caccaattgc ttagccttat
     6241 caattcgaac aacattgtca agattgacca agtaagaacg gtggcataaa aacagcttag
     6301 gagctaccgc atgaatctca gataagttcc cataaaattc taagcgctct gtttgcgtcc
     6361 acaggcacac cttgtgaggc gttgttgcag ttgcaaaata aagaatgtcc ttataaggca
     6421 gctttaggcg ggtctgcggg gtctcaaaca aaaacatctc ttctacttga cgactcgaca
     6481 tcatctcata ggtgtagcga atacattcct caatgcgctc tttaaattgc tgactatcaa
     6541 ccgctttatc aataaaatcc aaggcagaca ccttgtacct aaaggaaata ggggcgaact
     6601 ctgaatgcgt cgtgacaaaa acaagcacag cattgggatc cttctggcga atatctgagg
     6661 ctagctctag cccacttctt gatttgtcac caatttcaat atctaaaaaa tacagctgat
     6721 gatctcctct ctcctgaatg ctatcaaaca gcttttgagg atttgaaaac acctctaatt
     6781 gattatgagg aatcctaccc tcttctaata tggacgccac aatggcctca atacgacttt
     6841 gttgaatcag attgtcttcc agaataaaaa tgtttagcat ggcttatctc atttctaaca
     6901 attgtctcaa acggtagtga tcacttttgg ttgaaaaggt gatgtgggga tagcgctcta
     6961 acacagccga gaactgtagc aggcgcttat gagcatggct tcctagctcc aatcggctag
     7021 catcaaattg cttggcaata tcaacccgct tgagccttgt actattttca atgataaaaa
     7081 atcgcttgcc atcttgatta aaataggcaa tggataaaaa aggacgagag ctgcctttag
     7141 ctgacaaaat agcattatca ataactacct tgaaaagaac gatgacatct aacagcctga
     7201 cagaagagct agcaagcgtt tcaggaatat cgatgtaaac agcaatgccc tgcagctttg
     7261 cttctaatag cttggcatgc aataggctgc gaatcaccga atcctgaaca ttatcaaggg
     7321 ctgataattc aggtgttagc tgcctgatag agcttgctga ttcttggata actgtttgat
     7381 agaccttaga aatagcagct atatctccac tatcaatact atcctttaga ctaattagaa
     7441 tattttctga atcatgctta atagccctga tctcacgaca aagccgctca atatactgat
     7501 tgtgcttttc aaggtaagca acacgctcct tttgtgccag agccaatctt tgagatagct
     7561 gatccttagc aaagcggtcc agcttgacaa tgacccagat gagcagcatg aggtaaagaa
     7621 aaatcatgac agagcggtaa cgaaaataaa tcttgaaaaa atctccttgg atattgatca
     7681 tgcagtgaac catcacatag tagaaaagta aggctgcatt catccaaaag acccacttct
     7741 ttagcttgtc ctcactgata aacttaatca aggtcaaatc aacgctaaaa atatagctaa
     7801 acaggtaaaa ggccggcaaa accaatgcat gacagaccat caatagacct atgtcattat
     7861 tgatttgatg aatgctgtag cctaaaaccg ctggcaaaag gaaagagcca ataatacgaa
     7921 agagcagctc aacaatcata atcgcaaaca agccattaaa cagatgctca gaagcctttt
     7981 tatgaggtgc aaagccaaca ctgacagcaa caaacaccag ctgatcaact agcagcacat
     8041 gatccagcag cagattagca acaacaaagc aggcaccaac caaaagcaat gatctaacag
     8101 ctagcttaat gcctgaaaat gtcgaaaaga tgacccagct attcacaaag atcagagcat
     8161 aaaagaatga catacctagc ataaaataaa actctactct ttctctattt ttggcatgat
     8221 tagggtctga ctaaactgat aatcatgact cctggtgcgc aaggatagct caggatattt
     8281 ctgcaaaatc cgcttggcat tagacaagcc tatccctcga ccgctcccct ttgaggaata
     8341 gccctcttca aaaatcctac taatcatgac cctttcgtcc ttggtcgtat tggttacggt
     8401 gaaaatctgc tgatcatcag ataaaaagta ggctatcgcc actgctggct gggctgtctc
     8461 tagagcagcc tcaatagcat tgtcacaaaa aatagataca agcagcaata aatcaagctc
     8521 tgagatatag ctatcccgaa tccgatctgg aacttctagg cttaaggcga ttcctgcctt
     8581 ctcagcctta atgatttttg atgatagcaa gctttttatc gaggatacac tgattttact
     8641 gagctttgaa atattgtaat gcttatcgtc ccaataatcc gtcgcctcat ctaccgtttg
     8701 ggcatagaca gtctgtacat ctgacacaga gccagagtca atagcctgcc ccagcctttc
     8761 tagcctcttg aggtaaacta gctgaaatac cttaacaccc ttataaagct tttctagatg
     8821 ctttccatag gtttccagat tagcaatata agcctgctgt tcctttttta attcctgttt
     8881 taagaattcc tttgattgat gattaaaata agacagtaaa taaatcaaca atagggtaaa
     8941 gatgagaaac agcaccttat aagacgttga catcattatc ggggatttaa ggtcaagaaa
     9001 gggatcagta aatcctaaaa tcataaagag atcaatatag taggccaaac taaagagcaa
     9061 aaacaagcta taaaagctac tggccttatc aaacctgtca gctttaacaa tctgcttgta
     9121 atcctttccc acaaaataat taatcaaagc aaagcttggg aaaatcatca cataagcaat
     9181 aaagtctagg acaaggtgtc tgacatagct gccattaact gaaaaaatat agggaagtac
     9241 aatcgctaaa ataaagcgtg ataacaaatc aacaaacact ccgggaacaa aggccaagaa
     9301 tagagccttt aagctaaagc agggccgctt ttctaaggct aatacagcta gcagcaataa
     9361 aggatcaatt atcaagggcg gcaataaagc aaactgattc aaaaagagag ctgctgtcag
     9421 gacaaaaatc tgcttccaaa gtgccagttt aatgtctgat aaaaaggaaa aaatactaat
     9481 ttctgtcaca taataaatca tcagtgatag taataaaaag agataataaa tatcagtcat
     9541 tctgcctcct taccaacttt attat
//
LOCUS       DARYYD010000067         9313 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.068, whole genome shotgun sequence.
ACCESSION   DARYYD010000067 DARYYD010000000
VERSION     DARYYD010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9313
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.068"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(7..369)
                     /locus_tag="TV188_001695"
     CDS             complement(7..369)
                     /locus_tag="TV188_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1535025.1"
                     /translation="MHFKRRVKAGVLLYALLMASVFLLLLQAYLSHISQLHQEYQAQM
                     DYAKAQLIAEMVYQEQPSGDGQIAFNCGQVSYKSHKQRFIIEIKLPHQQLYQFSYPEV
                     QQASQTSKKQSELKQSLP"
     gene            complement(347..781)
                     /locus_tag="TV188_001696"
     CDS             complement(347..781)
                     /locus_tag="TV188_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1535026.1"
                     /translation="MKDSRLKAFTLIECLIALLVISGSLLVYQALTKSLMANERYLAA
                     NDQNNWLLFSQQLRAELSGTTLQGVRNNRLYVEKDKKALSFGQVKGHDFRKAASNGQG
                     YQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG"
     gene            complement(768..1058)
                     /locus_tag="TV188_001697"
     CDS             complement(768..1058)
                     /locus_tag="TV188_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComG"
                     /protein_id="HEL1535027.1"
                     /translation="MVIIKKQVKAYIALEGLIATGLILVIVTLILSALRYSQQELSAC
                     RQKQELLNTAVMAMQTKQRALSLNGCHIKLLSHQKGIAIVEKDQTIIRIERQ"
     gene            complement(1015..1440)
                     /locus_tag="TV188_001698"
     CDS             complement(1015..1440)
                     /locus_tag="TV188_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEL1535028.1"
                     /translation="MKLRSSIKAFTLLEGLLTLFLISFMLLYLSLPVSDSYARVEEHL
                     FFMRFEQAYRHLQKLSILRQKEHVLVLKPHYIKAEEAILPLPKQVKLKSTQTLTIDKL
                     GGNHSLARVVFENRDRQITYQFYLGSGNYQKTSQSLHRS"
     gene            complement(1418..1741)
                     /locus_tag="TV188_001699"
     CDS             complement(1418..1741)
                     /locus_tag="TV188_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HEL1535029.1"
                     /translation="MKMRLSILKDQGVQAFTLLEMLLVLLIISVLMLLFVPNLSKQKD
                     KVTDTGNAAVVKLVENQAELYELSHGEKPSLKQLQEDGSISDKQQKAYQDYYAKHKDE
                     AKKLN"
     gene            complement(1742..2728)
                     /locus_tag="TV188_001700"
     CDS             complement(1742..2728)
                     /locus_tag="TV188_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEL1535030.1"
                     /translation="MKKLSSKQQEKLIQLLYNLLSNGFNLTEVIAFLRKSQLLLPVYV
                     TSMEASLLKGNGLADMLAALGYSDAVMTQINLADKHGNIKLTLEKIQDYLSQFRQIKR
                     KTIEAVTYPIILLGFLVVIMLGLRHYLIPQLESQNTLTDLLLHLPHYFLGFCLLVLLL
                     IGSFYLYAKSCSRLKLFSQLSYYPIIGSLLRQYLTAYYAREWGNLIGQGLELITILEM
                     MSNEKSQLMRELAKDIKQSLLAGQSFHQRVAAYPFFKKELSLMIEYGDIKSKLGQELD
                     IYSQESWETFFSQLNRATQWIQPIIFLVVAVVIVMIYAAILLPIYQQMGDVF"
     gene            complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TV188_001701"
     CDS             complement(2709..3647)
                     /gene="tadA"
                     /locus_tag="TV188_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HEL1535031.1"
                     /translation="MIQELAKRLIRQAEELQAQDIYILPRGTGYELLMRVGDDRRLID
                     VCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYDLDDTKVSLRLSAVGDYQGQESL
                     VIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
                     VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVI
                     RASLTGAMVFSTVHAKSISGVYARLLELGISRAELDNSLAMVAYQRFISGGALIDCAQ
                     KEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ"
     gene            complement(3829..4476)
                     /locus_tag="TV188_001702"
     CDS             complement(3829..4476)
                     /locus_tag="TV188_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1535032.1"
                     /translation="MIRLEKVSKCFGDRVLFSDLSMTFESGKVYALIGSSGSGKTTLM
                     NMLAALEDYQGEIFFRGKNLKTYRSSDFFRHELGYLFQHFGLLESQTIADNLKLGLIG
                     QKISKEEGRQRELEALRAVGLDYLSLEKPVFELSGGEYQRVALAKVMLKDPPFILADE
                     PTASIDPEASKAIMAILLSLRHKNRTIIIATHSPSIWEMADEVISVDQLSSLTRL"
     gene            complement(4478..6481)
                     /locus_tag="TV188_001703"
     CDS             complement(4478..6481)
                     /locus_tag="TV188_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEL1535033.1"
                     /translation="MKRLFIILSNILVSLFLVWVFTIWSDTFVSHYYPSVVVLDASPK
                     ASYNQVEAGLTRLADETDSLIAMQHQEPGPEGTPIVTYTLFGKGKLPGGLAEKVIEEP
                     SRLSVENNYFILKGGLTVERLRDTLAGLGMTKMTALKPSFLGTLVLIFSSGSQALGIV
                     IFCLTFGALTLIGHIRTLRAVGIRLISGERRWQIFLYPIRSDVCYCCLGLLLGLSLAA
                     IMSQLMSFSPLVLYLIGIGLVCYNLLLIAIALFFAGLFVIGIKRVHLMQVIKGQIPVR
                     GIISLILIAQLLAVLVVSFGASRTLLYVQAERQQKQGQAAWLQEDRLVTLLIGRDGLD
                     IGNTKEAIAKQKTWFHVMDQAVSEHGAILSRHYLVERDLQSGLSMLTASSSWNDYSPQ
                     GNVLLVTPQYVKHQKVEVAPDISEKINQLSLGEFVLLLPEHLKTQAAQYQSVFESAVT
                     GLASGEGHQPMTATVSYTKTGQERFLYNTTPISYQQFLRDPIIVVLTPKSTGEQAYAF
                     WEVALQNYFLFDQLADTQTLIKQNGIENWVGELKTGYRIYETLLNNLRREIWLMIAGA
                     ILGIATSMLMFNTMNLLYFEEFRRDIFIKRVSGLRFFELHRRYLLSQLLVFFVGLVIS
                     ALLTQNPLMCLLVFFLFLGNAILLLYRQMRIENKMSLLILKGA"
     gene            complement(7018..7383)
                     /locus_tag="TV188_001704"
     CDS             complement(7018..7383)
                     /locus_tag="TV188_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEL1535034.1"
                     /translation="MYQVIEMYGDWEPWWFIDGWQDDIVQEKSFDSWPAALAYFEEEW
                     QRMKKSYPSYHSQKSLLATFWREDERRWCEDCDEELQQYHSLLLLKDRDIVPKHHYQS
                     YFEQRNDCPQASLSCKLSI"
     gene            complement(7444..8490)
                     /locus_tag="TV188_001705"
     CDS             complement(7444..8490)
                     /locus_tag="TV188_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001868451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEL1535035.1"
                     /translation="MTKESQKVTDSLNTSVVSLLQYCFAIMVIVIHSGRLFQYEPLHF
                     FLKSFLGRMAVPYFLICTAFFLRGRLREANREKQYFKQILKTYLLWSLIYLPYAYAFF
                     ESLRLPKHYLPLGLCLALSYFGMCYHLWYIPALWLGWVLVQLSLKTFGKKVTLIIVAG
                     LYLLGSMETYSHFLSSTPFEPLLTGYMHIFQTSRNGIFYTPAYLCAGCLLYDHFSSSL
                     FSQRYMRKAAVCLILLALESLLIYHHQGLDKNFFLLSALFTTFLFNASVRISLLSKYS
                     LAKLKKLSYYYFFLHPMFIECSLFLLRPYQLAPATKGKLVFLMTLLATHLCSEALMLL
                     VRSQAHAKAYLKRQ"
     gene            complement(9054..>9313)
                     /locus_tag="TV188_001706"
     CDS             complement(9054..>9313)
                     /locus_tag="TV188_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535036.1"
                     /translation="NKIVFTWKGYDLYLDSTNANRLSALGWGSTALSGLIPDPIVSKV
                     LAAALGVVSASISYANAAGRGVIVAFVGTFPRGVIHWVASQ"
BASE COUNT         2942 a         2113 c         1702 g         2556 t
ORIGIN      
        1 ccttagttat gggagtgatt gcttaagctc agactgcttt ttagaagtct gagaggcctg
       61 ctgaacttca ggatagctaa attgatatag ctgctgatgt ggtaatttga tctcaattat
      121 aaaacgctgc ttatgcgact tatagctaac ctgaccacaa ttaaaggcaa tctgaccatc
      181 gccagaaggc tgctcctgat aaaccatttc tgctattagc tgagcctttg cgtagtccat
      241 ctgagcctga tattcctgat gtagctggct aatatgacta agataagcct gtaacagtaa
      301 taaaaagacc gatgccatca gcaaagcata caaaagcact cctgccttaa cccttctctt
      361 gaaatgcata aataaaggtc ctttctaagc cgctttgcca tttcagcttg atggtcacct
      421 gctgacctac tgctgttatt tggctacttg acaagccaaa cagcatgggc tgatagcctt
      481 gaccattgct agctgctttt ctaaaatcat ggcccttgac ctgtccaaag gacaaagcct
      541 tcttgtcctt ttcaacatat agcctattat tgcggacacc ctgtagggta gtacctgaaa
      601 gctctgctcg caattgctgg gaaaacaaaa gccagttgtt ctgatcattt gctgctagat
      661 acctctcatt tgccataagg ctcttggtta aggcctgata aactaataaa gagcctgaga
      721 tgacaagcaa ggcaataagg cactctatca aggtgaaagc ctttagccta ctgtctttca
      781 atcctaataa tcgtttggtc tttttcaaca atagcgatac ccttctgatg tgataatagc
      841 ttaatatgac aaccattaag gcttaatgcc ctttgttttg tctgcatagc catcacagct
      901 gtattcaaca gctcttgctt ttggcgacag gccgacagct cctgttggct ataacgcagg
      961 gctgacagta tcagtgttac aataacaaga ataagtcctg tcgctatcaa gccttcaaga
     1021 gcgatgtagg ctttgacttg ttttttgata attaccactc cctaaataaa attgataagt
     1081 aatctgccga tctctatttt caaagacaac tcttgccagc gaatggttgc cgcccagttt
     1141 atcaatggtt aaggtctggg tagattttag cttgacctgc tttggtagag gcaaaatagc
     1201 ttcttcggcc ttaatataat gtggctttaa gaccagcaca tgctcttttt gacgtaatat
     1261 cgatagcttc tgtaggtgcc tataagcctg ttcaaagcgc atgaaaaaga gatgctcctc
     1321 aaccctagca tagctatctg ataccggtag tgacaagtac agcagcataa agctaatcag
     1381 aaaaagtgtc agtaaaccct ctaagagggt aaaagcttta attgagcttc ttagcttcat
     1441 ctttatgctt tgcataataa tcctgataag ccttttgctg cttgtcactg atacttccat
     1501 cctcttgcag ctgcttcagg cttggctttt ccccatgtga taattcataa agctctgcct
     1561 gattttcaac cagctttacc accgcagcat tgcctgtgtc tgtcacctta tccttttgtt
     1621 tacttaaatt tggaacaaat aacagcatca aaacactaat gattaacaaa accagaagca
     1681 tttccagtaa agtgaaggcc tgaacacctt gatcttttaa gattgataat ctcattttca
     1741 tttaaaaaac atctcccatc tgttgataaa ttggtaataa aatagcagca taaatcatca
     1801 caataaccac agcaaccact aaaaaaataa tcggctggat ccattgtgtt gcccgattaa
     1861 gctgactaaa aaaggtctcc cagctttctt gggaatagat atctaattcc tgaccaagct
     1921 ttgatttgat gtcaccatat tcaatcatta ggcttagctc ctttttaaaa aagggataag
     1981 ctgcaaccct ttgatgaaag gattggccag ctagtagact ctgcttgata tccttggcaa
     2041 gctctcgcat gagctgtgac ttttcgtttg acatcatctc taaaatggtg attaattcta
     2101 agccttgtcc gatgaggttg ccccattctc tagcatagta ggctgtcaaa tattgccgca
     2161 ataaggaccc aatgatagga taatagctca gctgactaaa tagttttagc cgactacagg
     2221 acttggcata taggtaaaaa gagccaatta gcaacagcac aagcaaacaa aaacctaaga
     2281 aataatgagg caaatgaagc aacaagtcag tcaaggtatt ttgactctct agctgaggga
     2341 ttaggtaatg acgcaagcct agcatgataa ccactagaaa acccaaaagt ataatcggat
     2401 aagtgactgc ctcgatggtc tttcgcttga tttggcgaaa ttgactcaga tagtcctgaa
     2461 ttttttccaa ggttagcttg atattgccat gcttatctgc cagattaatt tgtgtcataa
     2521 cagcatcaga gtaacctaag gctgctagca tgtcagcaag gccgttgccc tttaataggc
     2581 ttgcttccat acttgtaaca tagactggca gtagcagctg gctttttctc aaaaaagcaa
     2641 tgacctctgt caaattaaag ccgttagaca ataggttata gagcaattgg ataagctttt
     2701 cctgctgctt actggataat tttttcaagc cttgcctgcc tggtattgag atgtccctcc
     2761 gcaagaagct gatcaatctg ctgattccac cggttggctt gatgatgttc aaattccttt
     2821 tgtgcacaat caattaaagc acctccacta ataaatcgct ggtaagcaac cattgctaga
     2881 ctattatcca attctgccct agaaatgcct aattctagca gtctagcgta aacgcctgaa
     2941 atactctttg catggacggt tgaaaagacc attgctcctg ttaggctagc cctaataacc
     3001 gctctagcag tctgtgtatc tctaatttct ccgataatca acacatctgg acgatgacgc
     3061 aaggaaagct taatcagatt atcgtatgtc atgccaatgc tatcgttaac ctgtaattgc
     3121 aggagctggt cattttttat ttccacagga tcctcaatac tgatcacctg aagctccttg
     3181 caatagtcag agactagctg atacatcagg gttgtcttac ctgatcccac cggtccagaa
     3241 aagaggtaaa ggcctctagc tccaatagct gatgtgactc gctctaaacc atcaaaccaa
     3301 tacctgagct ggcgttgatg atgatacaag agacgaataa ccaagctctc ctgtccctga
     3361 taatcaccca cagctgataa tcgtagagac accttagtgt catcaaggtc gtagtcacaa
     3421 gcaccgagct gacagcgtct tttttcgccc acattcattc ctgcaacgaa cttaaagtga
     3481 ctaataagat tagccatccg atcactttca caaacatcta ttagcctcct atcatcacct
     3541 accctcatca aaagctcata gcctgtcccc cttggtagta tataaatatc ctgagcctgc
     3601 aattcttcag cctgcctgat aagccgcttg gctaattctt gaatcattct tacctcctca
     3661 ctaagactat tcgaaaaata aaaaaaatag cctcaagaaa aaggccattt tttgataaat
     3721 gtttaacatc aagtaaggaa ttcagcacgc tacaaacagc gcagaatcct tttgcgatgc
     3781 tatgatgaca aggtcaagcc ttaatcactt agctagtcca ggctttattt agagcctggt
     3841 gaggctgcta agctgatcaa cagagatgac ctcatctgcc atttcccaaa tgcttgggct
     3901 gtgggttgcg atgataattg tccgattttt atgccgaagt gacagcaaaa tagccataat
     3961 tgccttagaa gcctctggat caatagaagc cgtaggctca tcagctaaaa taaagggagg
     4021 atcttttagc atcaccttag ctagggcaac acgctggtat tcaccaccag acaattcaaa
     4081 aacaggcttt tctaagctca gataatccaa gccaactgcc cttagggctt ctaattccct
     4141 ttgccggcct tcctccttgc ttattttttg accaattagc cctagcttca aattatcagc
     4201 aatcgtctga ctctccaaca gcccaaaatg ctgaaatagg tagcccaatt cgtgacggaa
     4261 aaaatcgctg gatctgtatg ttttcaagtt ttttccacga aagaaaatct caccctgata
     4321 atcctcaaga gctgccagca tattcatcaa ggttgtctta ccactaccgc ttgacccaat
     4381 cagggcataa acctttccag actcaaaggt cattgacaaa tcagaaaata agacacgatc
     4441 accaaagcat ttactaacct tttctaatcg aatcatacta agctcctttc aaaatcagca
     4501 gcgacatctt attttctatt ctcatttgcc gatatagtag caatatggca ttccctagaa
     4561 ataggaagaa aaccagcagg cacataagag gattctgtgt taacagggca ctaatcacca
     4621 atccaacaaa gaaaacaagc agctgcgaca gcaaataacg acgatgcagc tcaaaaaatc
     4681 taagaccaga gacgcgctta atgaaaatat cccgtctaaa ttcttcaaag tagagaaggt
     4741 tcattgtgtt aaacatcaac atagaggtcg ctatccctaa tatagctcct gcaatcatca
     4801 accaaatctc cctacgaaga ttgttcaaca atgtctcata aatgcgatag ccagttttta
     4861 gctctcctac ccagttctca ataccgtttt gcttgatgag cgtttgagta tctgccaact
     4921 gatcgaaaag gaaataattt tgtaaagcaa cctcccaaaa ggcataggct tgttcgccag
     4981 ttgacttagg cgtcaaaaca acaataatgg gatcccttaa aaactgctga taggatatcg
     5041 gtgttgtgtt ataaagaaag cgttcctggc ctgtctttgt ataagaaaca gtagcagtca
     5101 tcggctgatg accctcacct gaagcaagcc cagttacagc tgattcaaag accgattggt
     5161 actgtgcagc ctgtgttttc aaatgctctg gtaaaagaag gacaaattct ccaagggaca
     5221 gctgattgat tttttcacta atatcaggtg ccacctcaac tttttggtgc ttcacatatt
     5281 gaggcgttac aagcagcaca ttcccttgtg gactgtaatc attccaacta gaagaggctg
     5341 ttagcataga gaggcctgat tgcaggtcgc gctcgactag gtaatgacga gacaggatcg
     5401 ctccatgctc tgaaacagcc tgatccataa catgaaacca agtcttttgt ttggcaatag
     5461 cttccttcgt atttccaata tctaagccat cacgtcctat taaaagagta accagcctat
     5521 cctcttgtag ccaagcagcc tgcccctgct tctgctgtct ttcagcctgg acataaagaa
     5581 gggtccggct agcgccaaag gaaacaacca gcactgccaa caattgggca attaaaatca
     5641 agctaatgat acctctgaca ggtatctgac ctttaatcac ctgcatcaaa tgcactcttt
     5701 taatcccaat tacaaataaa ccagcaaaga aaagggcaat agctatcagc aaaagattat
     5761 agcaaacaag acctatccca atcaggtaaa gaacaagcgg tgaaaaagac ataagctgac
     5821 tcataatagc cgccaggcta aggccaagta gtaggcctag acagcaatag cacacatcag
     5881 acctgattgg ataaagaaag atctgccagc gacgttcacc tgaaatcaag cggataccca
     5941 ctgctcgcag cgtgcgaata tggccaatca aggtcaaagc cccaaaggtt agacagaata
     6001 tcacaatccc taaagcctga gaaccactgc taaaaatcaa aacgagagtc cctaaaaatg
     6061 aaggcttcag cgctgtcatt ttggtcatac cgagcccagc taatgtgtct cttagtcgct
     6121 ctacagtcaa gccgccttta agaataaagt aattattctc cacactaagc cttgatggtt
     6181 cctcaataac cttttcagct agtccaccag gtagctttcc cttgccaaat aaggtatagg
     6241 tcacaatagg tgtaccttct ggccctggct cctggtgctg cattgcaatt aagctgtctg
     6301 tttcatctgc tagacgggtt aagcctgctt caacctgatt atagcttgcc ttaggcgaag
     6361 catctaaaac aacaacagac ggataataat gagaaacaaa ggtatctgac cagatcgtaa
     6421 atacccaaac caaaaagagg ctaactagta tattagacaa tatgataaac agtctcttca
     6481 taacccactc cttaccttaa aagggacgga gtctctccgc ccctaataaa cacacactga
     6541 cctgcctatt tccctgcatc aaaggtcacg tgctctccaa aattagtatt gataaaagca
     6601 taggagtagt aaccagcacc agaccatgca cgcctctgat tatcacgtcc tgagctctcc
     6661 acaaaggacc ggtgagaaga ggtcagaagg tcacctattg aaaacgcctt caatcataaa
     6721 ggacatggcg attaccacaa taccactcaa atcattaact atttaacaaa aatataccat
     6781 attctgttaa cgtttacaat gttatattta atccattttt ataaaaaaat aacattatat
     6841 catgcctcaa atgattttat cataatgagg ctcgctatgt tgttttctct atcccaatca
     6901 ggcactgcta gattagacat ctttccagac aacaaaaata gcctaaggtc agctctctaa
     6961 ttagctgatc ttaggctatt tgagtgataa tagatttgac tgatagctgt aagcctctca
     7021 gatgcttaat ttacagctaa gggaggcttg tgggcagtca tttctttgct caaaatatga
     7081 ctgataatga tgctttggca caatgtctct atcctttagc aataaaagag agtgatactg
     7141 ctgcagctcc tcatcgcaat cctcacacca tcttcgctca tcttccctcc aaaaggtagc
     7201 caataagctt ttttgactgt ggtagctggg atagctcttt ttcatgcgct gccattcttc
     7261 ctcaaaataa gccagtgcag caggccagct gtcaaacgat ttctcctgaa caatatcgtc
     7321 ttgccaacca tctataaacc accaaggctc ccagtctcca tacatttcaa tcacttgata
     7381 catgttctca tttcctctat tgcctattat agccgaagaa agatattttt aaaaaacatc
     7441 tgctcactgc cttttaagat aggccttggc atgagcttga gaacgtacca gcagcataag
     7501 ggcctctgag caaagatgag tagctagcag ggtcatgaga aagaccagtt tcccttttgt
     7561 ggccggggca agctggtagg gccttagcag aaatagcgaa cattcgataa acattgggtg
     7621 caagaaaaaa taataatagc ttagcttttt taatttagct aaagaatatt tagacagaag
     7681 gctgatacgg acactggcat tgaataaaaa ggtagtaaac agcgcagaaa gcaagaagaa
     7741 atttttatcc agaccctgat gatggtaaat aagcaggctt tccaaggcca ataagatcag
     7801 gcaaacagcc gcctttctca tatacctctg agaaaaaagc gacgatgaaa agtgatcata
     7861 gagcaagcag cccgcacaaa gataagcagg ggtgtaaaaa ataccattgc gacttgtttg
     7921 aaaaatgtgc atgtagcctg tcagcaaagg ctcaaaaggc gtcgagctta aaaaatgaga
     7981 ataggtttcc atactcccta gtaaatacaa gcccgccact atgatgagcg ttaccttctt
     8041 accaaaggtc ttcagagaaa gctgaacaag cacccacccc agccataaag caggaatata
     8101 ccacagatga tagcacatcc caaaataact aagggctaaa cacaagccaa ggggaagata
     8161 atgcttaggc agacgaagcg actcaaaaaa ggcataagca taagggaggt aaatcagaga
     8221 ccaaagcaaa taggttttta gtatttgctt gaagtactgc ttttcccgat tcgcctctct
     8281 aaggcggcct cttagaaaaa aggcggtaca aatgagaaaa taaggcaccg ccattcttcc
     8341 taaaaagctt ttcaaaaaga aatgcagcgg ctcatactga aacagcctac cgctatgaat
     8401 aacaataacc attatggcaa aacagtattg taacaggctt accacagagg tattgaggct
     8461 gtcagtgact ttctggctct cttttgtcat caattcaatc actttctttt aagagattaa
     8521 tatacgtata acttttagta tttatcgcat ttgtctctca ttttgattaa tattgttttt
     8581 atcatagcgt aatataacca attaatctaa tgattttagc ataacaaaag gagctaaggc
     8641 tagctcctga acatcacaaa agagcagacg aacttcatct cctctcgtgc ttagatataa
     8701 gccacccact acagttaaca tggagccata aaacgaagga attaactcct tcgttttctt
     8761 tcaatttttc ttggaatatt tttatagact tttcttacgg atatagtaag aataactacc
     8821 agcaataatg acataattca ataaaagaca taattaatca caacttgatt gtctttctaa
     8881 caaatccatt ccctgcctgg atcattagta tacgaaaaaa atgataggta aaactatacc
     8941 caataggcag aaaaaaactt tccaaaaaat agtattattt ttaaataatt tatcaacaaa
     9001 caccaataat atcaaattaa ttgctaaaca cagtattttt aaatataatg ctatcattga
     9061 gaagccaccc aatgtatcac acctcttgga aaagttccta caaaggcaac aattactcct
     9121 cttcctgcag cattagcata agatattgat gcagacacaa ctcctaaagc ggctgcaagt
     9181 accttagata ctatagggtc tggaataaga cctgacaaag cagttgatcc ccagcctagt
     9241 gcagataatc tattcgcatt ggtactatct aaataaagat catagccttt ccaagtaaaa
     9301 acaattttat tta
//
LOCUS       DARYYD010000068         9170 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.069, whole genome shotgun sequence.
ACCESSION   DARYYD010000068 DARYYD010000000
VERSION     DARYYD010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9170)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9170)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9170
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.069"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            101..1027
                     /locus_tag="TV188_001707"
     CDS             101..1027
                     /locus_tag="TV188_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1535037.1"
                     /translation="MEKIIITATAESIDQVKSLLAAGVDRIYVGEADYGLRLPHAFSY
                     DDLRQIAALVHKAGKELTVACNALMHQGMMDRIKPFLDLMKEIAVDYLVVGDAGVFYV
                     NKRDGYDFKLIYDTSVFVTSSRQVNFWGQHGAVESVLAREIPSEELFALADNLDYPAE
                     ILVYGASVIHHSKRPLLENYYHFTKIDDEVSRERGLFLAEPGDPDSHYSIYEDNHGTH
                     IFINNDIDMMTKLGELYEHGLTHWKLDGVYCPGENFVAITKLFIKAKALLESGQFTTE
                     LAQQLDAEVQGLHPVGRGLDTGFYDFDPKTVK"
     gene            1135..2421
                     /locus_tag="TV188_001708"
     CDS             1135..2421
                     /locus_tag="TV188_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEL1535038.1"
                     /translation="MSNVKKRPEVLSPAGTLEKLKVAIDYGADAVFVGGQAYGLRSRA
                     GNFSMEELQEGIDYAHKYGAKVYVAANMVTHEGNELGAGEWFRQLRDMGLDAVIVSDP
                     ALIVICSTEAPGLEIHLSTQASSTNYETFEFWKELGLTRVVLAREVNMAELAEIRKRT
                     EVEIEAFVHGAMCISYSGRCVLSNHMSHRDANRGGCSQSCRWKYDLYDMPFGSERRSL
                     KGEIPEEYSMSSVDMCMLEHIPDLIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     MESPEAFYAIKDDLIDELWKVAQRELATGFYYHIPTENEQLFGARRKIPQYKFVGEVV
                     SFDDDSMTATIRQRNVIVEGDRVEFYGPGFRHFETVIKDLHDADGNKIDRAPNPMELL
                     TISLPQAVKPGDMIRACKEGLVNLYQKDGTSKTIRA"
     gene            complement(2517..2842)
                     /locus_tag="TV188_001709"
                     /pseudo
     CDS             complement(2517..2842)
                     /locus_tag="TV188_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677676.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2977..3189
                     /locus_tag="TV188_001710"
     CDS             2977..3189
                     /locus_tag="TV188_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003049995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEL1535039.1"
                     /translation="MSEFTFKIEEHLLTLSESDKGWTKELNRVSFNGAEPKWDIRTWS
                     PDHTKMGKGITLTNEEFKTILDAFRR"
     gene            complement(4085..4225)
                     /locus_tag="TV188_001711"
     CDS             complement(4085..4225)
                     /locus_tag="TV188_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535040.1"
                     /translation="MKKEYISYLSAAIFILYALLSLKWIFFVLGVILLIIGLADRFRS
                     KP"
     gene            complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TV188_001712"
     CDS             complement(4588..6081)
                     /gene="lysS"
                     /locus_tag="TV188_001712"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014411828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEL1535041.1"
                     /translation="MSNQHIEELNDQQIVRREKMAALAEQGIDPFGKRFDRTTNSGEL
                     KEKYSDKTKEDLQELQATAIIAGRLMTKRGKGKVGFAHLQDRQGQIQIYVRKDSVGDD
                     NYDIFKKADLGDFIGVEGDIMCTDMGELSIKATKLTHLSKSLRPLPEKFHGLTDIETI
                     YRKRHLDLISNRSSFERFITRSKMISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFI
                     THHNAQDIDMVLRIAPELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYE
                     AYADYLDMMTLTEGIIQHAAKAVKGEGPIDYQGTEIKLHEPFRRVHMVDAIKEVTGID
                     FWPEMTFEEATALANEKHVPVEKHFTSVGHIINAFFEAFVEDTLIQPTFVYGHPVEVS
                     PLAKKNPEDSRFTDRFELFIMTKEYANAFTELNDPIDQLSRFKAQAAAKELGDDEATG
                     IDYDFVEALEYGMPPTGGLGIGIDRLCMLLTNTTTIRDVLLFPTMKP"
     gene            6424..7901
                     /locus_tag="TV188_001713"
                     /pseudo
     CDS             6424..7901
                     /locus_tag="TV188_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677680.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
     gene            8213..9118
                     /locus_tag="TV188_001714"
     CDS             8213..9118
                     /locus_tag="TV188_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEL1535042.1"
                     /translation="MISAIVFDVDDTIYDQQAPYRIAMEKCFPDFDMSLINRAYIRFR
                     HYSDVGFPRVMSGEWTTEYFRFWRCRETLLEFGYRDIDQATGVHFQEVYEHELQHITM
                     LDEMRMTLDFLKSKNVPMGIITNGPTEHQLRKVRKLGLYDYVDPKRVIVSQATGFQKP
                     EKEIFNLAAEQFDMNPATTLYVGDSYDNDVMGAKNGGWHAMWFNHRGRSLKPGTRPIY
                     DVAIDNFEQLFGAVKVLFDLPDNKVIFDINDKKNPVLQLGLNNGLMMAAERLLESNMS
                     IDKVVILLRLNKQQERVLRMKYANR"
BASE COUNT         2533 a         1730 c         2097 g         2810 t
ORIGIN      
        1 ttttttttga aggcttctcg ttataggcct tggtataggc gttaagattt tgaatgaatc
       61 atttttgaaa gcctaagaaa tttggtataa tatcccttgt atggaaaaaa taattattac
      121 agccacagca gaaagcattg accaagtcaa atcgctttta gctgcaggtg ttgatcgtat
      181 ttatgtaggc gaagctgatt atggcttgcg tcttcctcat gctttttctt atgatgactt
      241 gaggcagatt gcagcgcttg ttcacaaggc gggcaaggag ctaacagttg cttgtaacgc
      301 tctgatgcat cagggcatga tggatcgtat aaagcccttt ttggacctta tgaaggagat
      361 tgctgtcgat taccttgttg ttggtgatgc cggtgttttt tatgtgaata aacgagatgg
      421 ctacgacttt aagctgattt atgatacttc ggtttttgtt acctcaagcc gtcaggttaa
      481 tttttggggg cagcatggcg ctgttgaaag tgttttagct agagagattc cctcggagga
      541 attatttgcc ttggctgaca atcttgacta cccagcagaa atattggttt acggggcctc
      601 tgttattcat cattctaaga gaccgctcct tgaaaattat tatcatttta ccaaaattga
      661 tgacgaggtc agtcgagagc gtgggctttt cttagcagag ccaggcgatc ctgatagtca
      721 ttattctatc tatgaggaca atcatggaac tcatattttt attaacaatg acattgatat
      781 gatgactaag ctaggcgagc tatatgagca tggcctgaca cattggaagc tagatggtgt
      841 ttactgtcct ggtgagaatt ttgtggccat taccaagctg tttataaaag caaaggcttt
      901 gctggagtct gggcaattta ccacagagct agctcagcag cttgatgcag aagtgcaagg
      961 gcttcaccct gtagggcgtg gtctggatac aggcttttat gattttgatc ctaaaacagt
     1021 caaataagct ataacttgac ttgtcctgat taaggttact atttcaaggc atgacaagtt
     1081 aatcattcaa agatgttaca tcttacctat cttgaaaata gaaagaataa caacatgtca
     1141 aatgtaaaaa aacgtcctga ggtgctgtcg cccgcaggaa cacttgaaaa attaaaggtt
     1201 gccattgatt atggcgctga tgcggttttt gttggtggac aggcctacgg gctaagaagt
     1261 cgcgcaggaa acttctctat ggaggaatta caagagggga ttgactatgc tcacaagtat
     1321 ggggctaagg tctatgttgc tgccaatatg gttacccatg agggcaacga gcttggggct
     1381 ggtgagtggt tccgtcaatt gcgtgatatg gggcttgatg cggtcatcgt ttcagacccg
     1441 gcccttattg tgatctgctc aacagaagca ccaggacttg agattcatct atcaactcaa
     1501 gcatcatcaa cgaactatga aacctttgaa ttttggaagg aattaggcct aacgcgtgtc
     1561 gtgctagcac gtgaggtcaa tatggcagaa ttggctgaga ttcgaaagcg cacagaggtt
     1621 gagattgagg cctttgtaca tggtgccatg tgtatttcct attcagggcg ctgtgttctc
     1681 tctaatcaca tgagtcaccg agatgccaat cgcggaggct gctcacaatc ctgccgctgg
     1741 aagtatgatt tgtatgatat gccttttggc tcagagcgtc gttccttaaa aggagagatt
     1801 ccagaggaat actccatgtc ctcggttgac atgtgcatgc tggagcatat ccctgatttg
     1861 attgaaaatg gagttgatag cttgaaaatc gaagggcgca tgaagtctat ccattatgtg
     1921 tcaacagtga ccaattgcta taaagcagct gttgatgctt atatggaaag tccagaggca
     1981 ttttatgcta ttaaggacga ccttattgat gagctttgga aagtggctca gcgtgagcta
     2041 gcaactggct tttactacca tattccaact gagaatgaac agcttttcgg tgcgcggcgt
     2101 aagattccgc aatacaaatt tgttggggag gtggtttcct ttgatgatga cagcatgaca
     2161 gccactattc gccaacgtaa cgtcattgtt gaaggagaca gggttgagtt ttacggaccg
     2221 ggcttccgtc attttgaaac agtgatcaag gatttacatg acgctgacgg caataaaatt
     2281 gaccgtgcgc caaacccaat ggagctctta accatctcct tgccacaggc tgtcaagcca
     2341 ggagatatga ttagggcctg taaagaagga cttgttaacc tctatcaaaa ggacggaacc
     2401 agtaagacca taagagccta gcaccactag actaagcaat aggatttgac caattacttt
     2461 tgacacagag aagtgataag gttaggtctc ctttactcct gattagggta ctgagtctat
     2521 ggcttttctt tggtgctggt gcgtgtatga ggtactaagc tagccttatc aatatctgct
     2581 aaaaaaataa tgcagtcagg ttttgattgg tattttttaa gaccaattga ccggttagct
     2641 gatcgtattt tttaatgtgc ccagtgaagc ttttggcttg atagatcaca tgaattggaa
     2701 tctccttgac ctgtgcctct ttgatggtgg taatgatctg gttggccttg aggttaacgg
     2761 gagaagcctt ggcttttttg ggaggctgat tgtcaataaa gccgatcaag gctgattgca
     2821 gctgcttcat cattgatttc atagctattg tcctcaaaca ttgatagaat agtttgatag
     2881 tattttacct taaactatga tttttaaaaa gaatttactg ttttgcattc aatttttaat
     2941 attattttcg aatagataga tgaggaggaa aatataatgt cagaatttac atttaagatt
     3001 gaggagcatt tgctaaccct gtcagaaagc gataaggggt ggacaaaaga gctaaaccgc
     3061 gttagcttca atggagcaga gccaaaatgg gatatccgca cctggagccc tgatcacaca
     3121 aagatgggta agggcattac tctgaccaat gaagaattta agacaattct tgatgccttt
     3181 cgtcgttaag ccttagctta gtcatcaata acttcaatgt gagaagaacc ttttctaacg
     3241 aacagtatca accatcagtt actttgttct tgtaggaagg ttcttttgtt atctcttcaa
     3301 gtgagttttt aagagcaagg taaaagacta tcgtctagaa cccccttagc attcatagct
     3361 gctaccgcaa cgataaaagt taaaaaacaa actaactggg gatctggtat ctagaaagtt
     3421 aatctagtcc tcttagagct tttagtaact gttagtcact atttattggt gagaggaata
     3481 tatcacaatg ctccaatcga gccttggttt gggtgtttta agtccggatg ctatgagcta
     3541 aagtcatacc agacttgtga agagcctatc actgatagta atcgctatct ctacttttac
     3601 aatgatagtc atctttaaaa gcacatgaaa ggccctgccc ctcctttaag gaggaacaag
     3661 gcttctgttt aatcattatg agattagtat tcgcttaata ggaagtcact caagctcagc
     3721 gtctattttg agactgatgc ttctgtccta gccttaggct gctcatattc tgctctaaaa
     3781 tcatacggat tgtcctgatt tgctttagaa tagcatactt gttgagtcta ggtcccaagg
     3841 atcttgaatg actgacgttg aaggtgttta gctcctgtta tcttggtata agaaggtatg
     3901 accttttggt aattggattg tctattgtat ggttccaaga tgatgattgg catgcttggt
     3961 tgttgactgc aagctgatag ccttgtggga ggctttgctt tcataaggct taagggctat
     4021 ttttacttta atgtaaggct ccttggctgg cagctatcga gacttggaga tgatagaggg
     4081 ctagctaagg ctttgacctg aaacgatcgg ctagaccaat aatcaagagg atcaccccta
     4141 aaacaaagaa aatccatttc aagctgagta aggcataaag gataaaaata gcagctgaga
     4201 ggtaactaat gtattctttt ttcataagat gctccctatc tttttatact attgtagcat
     4261 aaaaatcagt ttaaatgctg atgaaatcaa tggctatttt ggctttcatt ggcctagtaa
     4321 aaaccgttta gcctagcagc atgtcatcat tgcaaacaaa aaagattgaa gaatcaagtc
     4381 taagagatga ttcttcaatc ctagtataca gacaagctaa ggacatcact tcaaaagtga
     4441 ggcttttaga gaagctaaag gcaactaatg actattagct aggcctagct atggaagtga
     4501 ttggtcatag tgatcattcg atctggataa gaggcttagg atcagctaga gaaagctgct
     4561 ttttaaacac tggtagctag tcgcttttta tggcttcatt gttgggaata acaaaacatc
     4621 gcgaatagtg gttgtatttg tcagcagcat gcagaggcgg tcaataccga ttccaagccc
     4681 gcctgttggt ggcataccgt attcaagagc ctcaacgaag tcgtagtcaa taccggttgc
     4741 ttcatcgtct ccaagctcct tggctgctgc ctgtgcctta aagcgtgaca gctgatcaat
     4801 tggatcattt agctcggtaa aggcattagc atattccttt gtcatgataa agagctcaaa
     4861 gcggtctgtg aagcgactgt cctcagggtt tttcttagca agcggtgaaa cctctacagg
     4921 gtgcccatag acaaaggttg gctgaattag ggtgtcctcg acaaatgcct caaagaaggc
     4981 attgatgata tgaccaacag aggtaaaatg cttttcaact ggcacatgct tttcgttagc
     5041 aagagctgtt gcttcctcaa aagtcatctc aggccagaag tcaataccag ttacctcctt
     5101 gatggcatca accatatgca cgcgtctgaa tggttcatga agcttgattt cagtcccctg
     5161 ataatcaatt ggtccctctc ccttgactgc tttagcagcg tgctgaatga ttccttcagt
     5221 tagagtcatc atatctaaat agtctgcata ggcttcatag acctcaatag aggtaaattc
     5281 tgggttatgt gtagcgtcca tcccttcatt acgaaagatc cgtccaattt catagacacg
     5341 ctccatgcca ccgacgatga ggcgcttgag atgcagctct ggtgcaatgc gaagcaccat
     5401 atcgatatct tgtgcattgt ggtgagtgat aaagggacga gcagcagcac caccagcttc
     5461 attatgaagg acaggtgtct ccacttctaa aaagccaagg ccatcgaggt aacgacgaat
     5521 ttcagaaatc atttttgaac gtgtgatgaa ccgttcaaag ctgctgcggt ttgaaatcaa
     5581 atccagatga cgcttgcgat aaatggtttc gatatcagtt aagccatgaa atttctctgg
     5641 tagcggacgt agagatttgg atagatgggt cagttttgtg gccttgatag acaactcacc
     5701 catatcagta cacataatgt cgccttcgac cccgataaaa tcaccaaggt cagctttttt
     5761 gaaaatgtca tagttgtcat caccaactga atccttacga acatagattt ggatttgccc
     5821 ttggcgatcc tgaagatgag caaagccgac ctttccttta ccacgcttgg tcatcagacg
     5881 accagcaata atcgcagtgg cttgaagctc ttgtaaatcc tctttggttt tgtctgagta
     5941 tttttccttt aattcaccag aattagttgt tcggtcgaag cgtttgccaa atggatcaat
     6001 gccttgctca gctaaggctg ccattttttc acgacggaca atttgttgat catttaattc
     6061 ttcgatgtgt tgatttgaca tgttttcctc caatactttt ccttcctatt gtaacataaa
     6121 agattataga atacacctat atttcgtggg aattctatca tcgaagcctc agatgatagg
     6181 cctttgactt gtatagataa attggttttg tctgagttgg tttttctgta taaataagct
     6241 attatttgtg agatcttact tgaattgaag gcttttgcta gttccaatag attatttttg
     6301 atgatatttg acaaaaaaac ttaaattgtg aaaaaatatt aatcgaaaaa atcaaaaaac
     6361 tctcaacgct aaggctagtc tttgtgcagt tgagggtttt tatcaggaaa ggatcataaa
     6421 gaaatggaaa cttatgatat acacgggaag ccttatcatc gaacgctgat gattatattg
     6481 ctgttggtgg gaacctttgc aggggtttta aaccaaacaa gcttggggac agctatacca
     6541 acattgatgg aaaattttaa ggtacctttg tcaacaactc agcaggcaac cacttggttt
     6601 ttgcttgcta atggcattat gatccctgtt tcggcctttt tagcaacgcg attttccact
     6661 aaaagactct acatgacagc ttatgctatt cttgtgagtg gcttgttact agcagctctg
     6721 gctccgactg ctcattgggg agttttttaa cagcacgtat cgttcaggct tgtgcagtgg
     6781 gcattaccat gcctttgatg caggtggtga tgatcaacgt ttttcctgca gagcagcgtg
     6841 gtgcagcaat gggaatcaat ggcttggtgg ttgggctagc tccggctgtt ggaccaacct
     6901 tgtcaggctg gattttgaaa aaggattttt cagtattagg catttattta ggctggcggg
     6961 ccatttttat cttgccttta gtgattttgc tgttggtttt aagcctgtcg cccttcatgc
     7021 tccgagatgt tatccctcag caggctgtta agcttgattc aacatctcta ggcttatcta
     7081 tcttagggct gggtgctttt ctctggggct ttacaaatgt tgcagcttat ggctggctag
     7141 atatggtgta cgtgatttta cctattttag tcggtattgg tggaatttac ctcttttcca
     7201 agcgtcagct acaattagag aagccctttt tagatattag agtctttcgc aacaagcaat
     7261 ttaccttgac aacaatagca attgccctaa cgatgatggc tatgatcggt gttgagatga
     7321 tgctgccgct gtatctgcaa aatgtcagag gcttatctcc attaaattcc ggaatggttt
     7381 tgttgccggg tgctttgatt atggggctga tcagtccagt ttctggccga atttatgaca
     7441 agatcggtgc tcgttatctg gcgctattag gctttaccat tttagctgcg gcgactctac
     7501 catttgtatt tctaaatgaa aatacctcac gctttttgat tactgttttg tatgccatta
     7561 gaatgtttgg catatcaatg attttaatgc ctttaactgc aagtgctatg aatgccttgc
     7621 catcgcatga atcggcgcat ggaacggcag ctaataatac tgtacgccag atctcctctt
     7681 ctattgttgt ggcggtgtta tcgagtgtga cacaaaacat tatcagcagc aaacagccgc
     7741 ctaaaatgct cctatccata caccctgagc aatacgctaa gaagcttcta gaagccaatt
     7801 taaatggctt tcatgcctct tttttccttg gctttatgtt tgcagtggta ggctttattg
     7861 ttgtgctttt cctacataag ggaaaggtta tcgagaaata gctcctgatt agtgtggtta
     7921 aaacaaatag gctaaaggcc tcacgccaaa cgcatgaaaa aacagctgtt tttgatagct
     7981 tttctgatta atgcactctt tttcaagaaa acttatggca caatgaagct aaatgtgagc
     8041 agttgatgat gtcaaaataa tggaaaatct attgaaaaat gtttgagtct agaaaattgt
     8101 tacctgcatt ttctttgtgt ctctagcatg ctaaaagcat gggctggttt gaaaagtcga
     8161 tgacaaaata gtataatgat aagcatatca acctagaaaa gaaaagagac tcatgatttc
     8221 tgcaattgtt tttgatgtag atgatacgat ttatgaccag caggcgcctt accgtatcgc
     8281 aatggaaaag tgctttccag attttgatat gtcattgatc aatcgagcct atattcgttt
     8341 tcgccattat tctgacgttg gatttccaag agtgatgtca ggtgagtgga cgacagaata
     8401 ttttcgattt tggcggtgtc gggagaccct gcttgagttt ggctatcgtg acattgatca
     8461 ggcgacagga gtgcattttc aagaggtcta tgagcatgag ctgcagcata ttaccatgct
     8521 tgatgagatg cgcatgacac ttgatttctt gaagtcaaaa aacgttccga tggggattat
     8581 cacaaatgga cctactgagc accagctaag gaaggtgcgt aagctagggc tatacgatta
     8641 tgttgatcct aagcgcgtga ttgtcagtca ggcgacaggc tttcaaaagc cagaaaaaga
     8701 gatattcaac ctagcagcag agcagtttga catgaaccct gcaacaaccc tctatgtcgg
     8761 cgactcttat gacaatgatg ttatgggagc taaaaatggt ggctggcatg ccatgtggtt
     8821 taaccacaga gggagaagtc taaagcctgg gacaaggcct atctatgatg tggccattga
     8881 taactttgag cagctgtttg gtgctgttaa ggtcttgttt gatctgccag acaacaaggt
     8941 tatttttgat atcaacgaca agaaaaaccc ggtgctgcaa ttaggactta acaatggttt
     9001 gatgatggca gcagagcgct tgctagaaag taacatgagt attgataagg ttgttatcct
     9061 gttacgcttg aataagcagc aagaaagagt gctgcgcatg aagtacgcta atagatagca
     9121 gttattgatt gaaaagcatg ctatgtttaa ttggcactcc aaaggctaga
//
LOCUS       DARYYD010000069         9093 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.070, whole genome shotgun sequence.
ACCESSION   DARYYD010000069 DARYYD010000000
VERSION     DARYYD010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9093)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9093)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9093
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.070"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TV188_001715"
     CDS             complement(380..2554)
                     /gene="nrdE"
                     /locus_tag="TV188_001715"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEL1535043.1"
                     /translation="MSQKESYLSLNALTRFKRADGTYHFDSDKEAVQRYLEEHVYPQS
                     LSFDSLEEKWRYLVAHDYYDQEILKAYSAECITEAFTYAYQQKFSFLSLMGAMKFYQS
                     YALKTLDGSQYLEHFEDRAVMNALFLANGDPDLVRDLIDQILSGRFQPATPTFLNAGK
                     KRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREVGSPIKGIENQ
                     ATGIVPVMKLLEDSFSYANQLGQRQGAGAVYLNVHHPEILTFLDTKRENADEKIRIKS
                     LALGVVIPDITFQLARENKDMALFSPYDIKRVYGKDMSDIAITEEYDRLVANPAIKKT
                     YISARKLFQLIAELHFESGYPYLLFDDTVNKRNPHPQKGRIVMSNLCSEIAQVSTAST
                     FEEDLTFKQIGEDICCNLGSINIAEAMKHAVGFEQLIATSVRALDHVSRASDVSCAPS
                     VEKGNAANHAVGLGAMNLHGFLATNHIFYDSAEAVDFTDLFFHTMAYYAFKASSQLAK
                     EKGAFAGFEQSTYADGSYFARYLTKEAKPKTAKVAALLERYGLRVPSVADWQELVATI
                     QETGLANAHLMAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGHLGRIYVPAYQISDDN
                     YAYYERGAYEVGPEPIINIVAAAQKHVDQAISLTLFMTDQATTRDLNRAYIHAFKLKC
                     ASIYYVRVRQDVLEGSEQYEEDTIVALTDTNASGEACQSCML"
     gene            complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TV188_001716"
     CDS             complement(2601..3008)
                     /gene="nrdI"
                     /locus_tag="TV188_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEL1535044.1"
                     /translation="MAARVMLVYFSSRSNNTHRFVQKLDVRALRIPVTGEPLLVDEDY
                     ILIVPTYAAGGSDSKGAVPKQVIHFLNKANNRRHCKGVISSGNTNFGDTFAIAGPIIA
                     QKLQVPLLHQFELLGTQRDVIKVQAILAGDEAL"
     gene            complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TV188_001717"
     CDS             complement(3010..4023)
                     /gene="nrdF"
                     /locus_tag="TV188_001717"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEL1535045.1"
                     /translation="MTQYYYDRSQSPIDYALSQTKKSLRSVNWNQLNDDKDLEVWNRV
                     TQNFWLPEKVPVSNDLNSWRSLGEDWQRLITRTYTGLTLLDTVQATVGDVAQIQHSLT
                     DHEQVIYTNFAFMVAIHARSYGTIFSTLCSSQQIEEAHDWVVSTESLQERARVLIPYY
                     TGDDPLKSKVAAAMMPGFLLYGGFYLPFYLSARGKMPNTSDIIRLILRDKVIHNYYSG
                     YKYQQKVAALSPEKQAEMKAFVFDLLYQLIDLEKAYLRELYDGFDLADDAIRFSVYNA
                     GKFLQNLGYDSPFTEEETRISPEVFAQLSARADENHDFFSGNGSSYVMGVTEETIDDD
                     WEF"
     gene            complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TV188_001718"
     CDS             complement(4704..6707)
                     /gene="metG"
                     /locus_tag="TV188_001718"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003006062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEL1535046.1"
                     /translation="MTKKKPFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRMLGYD
                     VFYLTGLDEHGQKIQDKAQEAGLSPQAYVDGMAEEVKALWKLLDISYDKFIRTTGDYH
                     EEVVAAVFERLLAQDDIYLGTYSGWYSVSDEEFFTESQLAEVYRDEAGKVIGGVAPSG
                     HEVEWVSEESYFLRLSKYADRLVAFFKAQPDFIQPDGRMNEMLKNFIEPGLEDLAVSR
                     TTFTWGVPVPSNPKHVVYVWIDALLNYATALGYGQKDHANFDKFWSGRVFHMVGKDIL
                     RFHSIYWPILLMMLDLPMPERLIAHGWFVMKDGKMSKSKGNVIYPEMLVERFGLDPLR
                     YYLMRSLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVAMINKYFDGRVPAYVRNV
                     TAFDADLEQVVADHISEYHKQMEAVDYPRALEAVWTIISRTNKYIDETAPWVLAKAAD
                     SKEQLASVMAHLAASLRVVAHLIQPFMMTTSAAIMEQLGLGAKYHLEELDLADLPTGV
                     TVVAKGEPIFPRLDMEAEIDYIKEQMTMSIAKPQEADWDPEKVALKSEKDTITFEAFD
                     AVEIRVAEVKEVSRVEGSEKLLRFRLDAGDGSDRQILSGIAAYYPNEQELVGKKVQIV
                     ANLKPRKMMKKYISQGMLLSAEHDGKLTVLTVDPAVPNGTIIG"
     gene            complement(6925..7623)
                     /locus_tag="TV188_001719"
     CDS             complement(6925..7623)
                     /locus_tag="TV188_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEL1535047.1"
                     /translation="MSKRKRKTYQVYEGLRCAMMLCFISGYVNAFTYMTQGRRFAGVQ
                     TGNLLSFAIRLSERQFDQALQFLLPIIVFMIGQAFTYFMHCWANKHGLHWYLLSSFIL
                     TLIALVTAILTPLLSSFFTVSALAFFASIQVDTFKTLRGASYANVMMTGNIKNAAYLL
                     TKGLYENNKELVHIGRNTLIIILSFALGVVCSTLLSLSYGEYALSPMLIPLCYVNYLL
                     AQEFYHHQVSLKND"
     gene            complement(8009..9030)
                     /locus_tag="TV188_001720"
                     /pseudo
     CDS             complement(8009..9030)
                     /locus_tag="TV188_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515161.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
BASE COUNT         2679 a         2155 c         1779 g         2480 t
ORIGIN      
        1 aatattttag aaatactata ggttattttg aatcttctga ttgttttgac agttacaaga
       61 aatcccagtg attaacacgg agacaagccc cagtaattat cgattgaaga gggagctttt
      121 ttcttgattc tccttaagca aatcagcaag cattggctta tccaagccaa atgtccttac
      181 aacaagcacc ggtagcccac ttcatttgac aaggggcttg tcagcaagca ttgatcacaa
      241 atcaggctga gctgcattaa gctcaagaga gcttgccatc agcctgttgg atcaagcgat
      301 actataagcc tattaacaaa ctggctagac agagcatgaa ggctgattgg tgctgcctat
      361 ttttaaggct aaaaaagatc taaagcatgc aggattggca tgcctcgcct gaagcattgg
      421 tatcggtaag cgctacaatc gtatcttcct catactgctc acttccttcc agaacgtcct
      481 gtctgacgcg aacataataa atggacgcac actttaactt aaaggcgtgt atataggcac
      541 ggttgagatc acgtgttgtt gcttggtctg tcataaatag ggttaaggaa attgcctgat
      601 caacgtgctt ttgagccgct gctacgatat taataatagg ctcaggccca acctcatagg
      661 caccacgctc gtaataagca tagttatcat cgcttatctg ataagcaggc acataaatcc
      721 ttcctaagtg cccctccttt cgcacctcaa ctggtgcaac aacaggctgt aagctcggcg
      781 tacatgagga caagtagctg atcgagccgg ttggtgcaac tgccatcaag tgagcattgg
      841 caaggcctgt ctcttgaatc gtcgcaacta attcctgcca atcagccaca ctaggcactc
      901 gaagcccgta gcgctcaagc aaggccgcaa ccttagctgt cttaggctta gcctcttttg
      961 tcaaatagcg ggcaaagtag ctgccatctg cataggttga ctgctcaaag ccagcaaatg
     1021 ctcccttttc cttagctaat tgactagaag ccttaaaggc ataataggcc attgtgtgga
     1081 aaaagagatc agtaaaatct actgcttcag ctgaatcata aaagatgtga ttggtcgcca
     1141 aaaagccatg taaattcatc gcgccaagac caacagcatg attagcagca ttcccctttt
     1201 caacagaagg agcgcagctg acgtctgagg cccttgacac atggtccaag gccctaacac
     1261 tagttgcaat caattgctca aagccaaccg catgcttcat ggcttcagca atattaatag
     1321 agccaaggtt acagcaaatg tcctcgccga tttgcttaaa ggtcaaatcc tcttcaaagg
     1381 tgcttgctgt gctgacctga gcgatttcag agcaaaggtt tgacatgaca atccgcccct
     1441 tttgtgggtg tggattgcgc ttattaaccg tatcatcaaa caagagataa gggtagccag
     1501 attcaaaatg aagctctgca ataagctgaa agagcttacg ggcactgata taggtctttt
     1561 taatggctgg gttggccact aggcggtcat actcctcggt aatggcaata tctgacatgt
     1621 ccttgccata aactcgctta atgtcatagg gagaaaatag cgccatgtcc ttattttccc
     1681 gcgccagctg aaaggtaata tcaggaatga caacgcctaa cgccagtgac ttgatacgga
     1741 ttttttcgtc tgcattttct ctcttcgtat ctaaaaaggt cagaatctct gggtgatgca
     1801 cattgaggta aaccgcacct gctccctgtc tttgccctag ctgattggca taggaaaagg
     1861 aatcctccag tagcttcatc actggcacaa tgcctgtcgc ttgattttca atgcctttta
     1921 tgggagagcc aacctctctt agattggtta aacacaaagc aacgccgccg cctcgttttg
     1981 agagctgcaa gctcgtacca atcgcacgcg aaatagattc catgttgtct tcgattcgca
     2041 gcaaataaca ggaaatatat tcgcctcgac gctttttacc tgcatttaaa aaggtagggg
     2101 tcgccggttg aaagcgcccg ctaagtatct gatcaatcaa atcccgcacc aaatcaggat
     2161 caccattagc caaaaacaag gcattcataa cagcacgatc ctcaaaatgc tctaggtatt
     2221 gtgacccatc tagggtttta agcgcatagg actggtaaaa tttcatggct cccattaagc
     2281 tcaaaaatga gaacttttgc tggtaagcgt aggtaaaggc ttcagtgata cattcagccg
     2341 aataagcctt taaaatctct tgatcataat aatcatgcgc caccaaataa cgccatttct
     2401 cctccaaact atcaaaggat aggctttgtg ggtagacatg ctcctctaaa tagcgctgaa
     2461 cagcttcctt atcactgtca aagtgatagg taccatctgc tcgtttaaag cgtgtaaggg
     2521 catttaatga gaggtaggac tctttttgtg acattctttt ttcctttcgt tacaatgtgt
     2581 gatcgttttt ctatcattag ttataaggct tcatcacctg ctaaaatagc ctgcaccttg
     2641 atgacatctc tttgtgtccc cagcaattca aattggtgca aaagcggcac ctgcaatttt
     2701 tgtgcaatga ttggtcctgc aatggcaaag gtatcaccaa agttagtatt gccagaggaa
     2761 ataaccccct tacagtgcct tcgattgtta gccttgttta gaaaatgaat cacctgcttg
     2821 ggaacagctc ccttgctgtc tgagccacca gcagcatagg tagggacaat caaaatataa
     2881 tcctcatcaa ctaatagagg ctcaccagtg actggaattc ttagagctct tacatctagc
     2941 ttttgcacaa agcggtgagt gttgttagat cgcgatgaaa aataaacaag cattaccctt
     3001 gcagccatct taaaactccc aatcatcatc aatggtttcc tcagtaactc ccatcacgta
     3061 agaagagcca tttcctgaga aaaagtcatg gttctcatct gctcgcgctg atagctgagc
     3121 aaatacctca ggggaaatac gtgtttcctc ctcagtaaag ggagaatcat accctagatt
     3181 ttgcaaaaat tttccagcat tatagacgct aaagcgaatc gcatcgtcag caagatcaaa
     3241 gccgtcatac aattccctca ggtaagcctt ctccaaatca atcagctgat aaagcagatc
     3301 aaacacaaag gccttcatct cagcctgctt ttcaggactt agggctgcca ccttttgttg
     3361 atacttgtag ccactgtaat aattgtgaat gaccttatct ctcaggatta agcgaataat
     3421 atctgaggta ttgggcattt tgcctctagc tgacaggtaa aaaggcaggt aaaagccacc
     3481 atatagcaaa aatcctggca tcatagctgc tgcgacctta gacttcagag ggtcatcacc
     3541 agtataatac ggaatcaaca cacgcgctcg ctcctgtaag ctctctgttg acaccaccca
     3601 atcgtgggcc tcctcgatct gctgactgct gcacagggtc gaaaagattg tcccatagga
     3661 cctagcgtga atagcaacca taaaggcaaa attagtataa atcacctgct catgatcggt
     3721 caaagaatgt tgaatttgtg ccacatctcc aactgttgct tgaaccgtat ctagcaaggt
     3781 caagccggta taggttcttg tgatgagcct ttgccaatcc tcccccaaag aacgccaaga
     3841 attaaggtca ttagaaacag gaaccttctc aggcagccaa aaattttgcg tcacacggtt
     3901 ccagacctcc aggtccttgt cgtcattaag ctgattccaa ttgacagagc gcaaactttt
     3961 tttggtttga gacaaggcat agtcaatggg tgactgtgat cggtcgtaat aatattgggt
     4021 catgttttct ccttcaagct tgatagtcgc aatatcaatc cttcagctgc caagccttct
     4081 acagctttag gactagggaa gactgctaag tgccacattt agacaacaca aaaagacttg
     4141 ctctaaaggg caatcctaca ggctaatgat aatttcttgc tgatgatccc taaccagtca
     4201 gcaactgctt tgtaagcaag gctaagcccg cttttttccc cggctgaatt aagtatactt
     4261 aattcttatg tttgttataa taacacaata tatagtgctt tgcaatcttt ttgatacaat
     4321 atatagatta atttatgaaa aagaaatcat aaaaggagct agcagcacct taacgaaagc
     4381 cctgtctgta tgctcaccaa tccctcatct gccaacttgc ttttcaaata agatcaatac
     4441 atatcaattc acacccccat gaagggagcg actagagcgt gagataaaga aacaaaaatg
     4501 atgtattttc aatactcaga gctttcactg ctgttattgc ctattaggct gctagactag
     4561 tgcttctttc ttgttcaaag tttacaaagc tcccacaaga agtctaggtc tcttgtcttt
     4621 ttaagacact aaaaatcccg tatgctcctg ctaatcaatc tattagcaag acccatacgg
     4681 gatattgtca tctaaaagcc caatcagcca ataatcgtac catttggcac tgccggatca
     4741 accgtcagca ctgtcagctt gccatcatgt tctgctgaca aaagcatgcc ctgactgata
     4801 tattttttca tcatttttcg cggcttgagg ttggcaacaa tttgcacctt cttgccaacg
     4861 agctcttgtt catttgggta ataggctgca atacctgata agatttgacg atcagagcca
     4921 tcacctgcat ctaatctaaa gcgcagcagt ttttcagagc cttcaactcg tgacacctct
     4981 ttgacctctg ccacacgaat ctcaactgca tcaaaagcct caaaagtaat cgtgtccttt
     5041 tcagacttaa gggctacctt ttcaggatcc cagtctgctt cttgtggctt agctatgctc
     5101 attgtcattt gctctttgat atagtcaatc tctgcttcca tatcaagacg agggaagatt
     5161 ggctctcctt tggcaacaac cgtcacacct gtcggaagat ctgctaaatc aagctcttcc
     5221 agatgatatt tggcaccgag acctagctgc tccataatag cagctgaggt tgtcatcata
     5281 aatggctgaa tcaaatgagc caccacgcgc agacttgcag ctaaatgtgc catcacactg
     5341 gctagctgct ccttactatc agctgctttg gcaagcaccc aaggagcagt ttcatcaatg
     5401 tatttgttcg tgcgtgaaat aatcgtccat acggcctcca aggcacgtgg gtaatcaaca
     5461 gcctccattt gcttgtggta ttcggaaata tgatcagcca caacctgctc cagatccgca
     5521 tcaaaagctg taacgtttct gacataagca ggaaccctgc cgtcaaagta tttattaatc
     5581 atggcaactg tacgattcaa aaggttacca aggtcattag ccagctcata attgatacga
     5641 ccaacataat cctctggggt aaaggtacca tcagagccaa ccggcaagga acgcatgagg
     5701 taataacgca gaggatcaag accaaagcgc tcaaccagca tttcaggata gatcacattc
     5761 ccctttgatt tagacatttt accgtccttc atgacaaacc agccatgagc aatcaaacgc
     5821 tctggcattg gtaaatcaag catcatcaac aaaattggcc aataaatgct gtggaaacgc
     5881 aaaatatcct taccaaccat atggaaaacc ctaccactcc agaacttatc gaagttagca
     5941 tgatccttct gaccgtagcc tagtgctgtt gcatagttta agagagcatc gatccagaca
     6001 taaacaacgt gtttaggatt tgacggcaca gggacccccc aggtaaaggt tgttcggcta
     6061 accgctagat cctccagacc tggctcgatg aagtttttaa gcatttcatt catacgaccg
     6121 tccggctgaa taaaatcagg ctgagcctta aagaaggcaa ccaatctatc cgcatacttg
     6181 ctcaggcgca aaaaataaga ttcttcagag acccattcga cctcatgccc tgatggtgcc
     6241 acaccaccaa tgaccttgcc agcttcatcg cgataaacct cagctaactg actttctgta
     6301 aaaaattcct catctgaaac agaataccag cctgaatagg tccctaaata aatatcatcc
     6361 tgcgccagca acctctcaaa tacagcagca accacctcct catgatagtc gccagtggtg
     6421 cggataaact tatcataaga gatatcaagg agcttccata gtgccttgac ttcctcagcc
     6481 atgccatcaa cataagcttg aggggataag ccggcttctt gtgccttatc ctgaatcttt
     6541 tgaccatgct catcaagacc agtcaaataa aaaacgtcat aacccaacat acgcttatag
     6601 cgagcaagaa catcacaggc aatcgtagta taggcagagc caatatgaag cttccctgac
     6661 gggtagtaaa tcggtgttgt aatataaaat ggttttttct tagtcatctt acgtcctttc
     6721 aaggctaatg aaacctttgt aatcagggac tagggcaata cccattccca agctgagtcc
     6781 tgtcagctat caactgacat tataccataa ttttagcata aaaaaatgat cactcagcct
     6841 attaactgat acctccccca taatagacaa tgacaaacaa gcagtcatca aaaattatag
     6901 gaggaggata tcaattagta gacttcaatc atttttcaat gatacctgat gatggtaaaa
     6961 ttcctgtgcc aagaggtagt tcacgtagca caatgggatc agcatgggag ataaggcata
     7021 ctcaccatag gatagtgata aaagagtaga acagaccact ccaagggcaa aggagaggat
     7081 aataatcaag gtattgcgac caatatggac tagctctttg ttgttctcat atagtccctt
     7141 tgtcaatagg taggcagcat ttttaatatt accagtcatc atcacattgg catagctcgc
     7201 accgcgcaag gttttaaagg tatctacctg aatcgaagca aaaaaagcta gagctgaaac
     7261 cgtaaaaaat gacgacaata agggtgtgag gattgctgtc acaagagcaa tcagggtcaa
     7321 gataaagcta gacaaaaggt accaatgcag accatgctta ttggcccagc agtgcataaa
     7381 gtaggtaaag gcctgcccaa tcataaaaac aatgataggc aataaaaatt gcagggcttg
     7441 gtcaaactgg cgctcagaca gacgaatcgc aaaggataag agattgcctg tctgaacccc
     7501 tgcaaagcgc ctgccttgcg tcatgtaggt aaaggcattg acataaccac tgataaagca
     7561 aagcatcatg gcgcacctta agccctcata tacctgatac gtttttcgtt tcctctttga
     7621 catacttgcc ttccttaatg tgattccaaa agaaaaatac tgacaaacag tatttgatgt
     7681 gattattagg aggataagct aagctcaatt gcccttgatc acagatagtc accaaagcaa
     7741 gttctgcagc tagactcggt aagtccccca aatacagctt tagtatagca taggcagtct
     7801 cttttatcaa gatgctttgc aggatcaact agcaccataa gactaaccat tagccaaaaa
     7861 gtactcaccc tctatgagga ccagcaggta aacctgataa aaaaactaaa aagccaccat
     7921 ttctgatgac ttcttagtcg gcctcttcaa caacttgtag cttacacaag ctatagcgct
     7981 aaggacagcc tttcattgga gcacaacatt agtcttcctt gcgttttgtt gacacaacaa
     8041 ccacacctgc acttgccatc actgcaagag ctgccgctgt gaagaatgga tgtgtcgctt
     8101 cacctgttga tggaagcttc ttagcttctt gcttaggtgc tggtttcttc tcttccttct
     8161 tagcttcagg ttttggttct ggcttaggct caggttttgg ttctggttta ggctcaggtt
     8221 taacctcttc atacacataa accacacgaa gatcgccttc tagggttgta ccagtttcgc
     8281 taggtgagcc ctcttgaagc ttcttgaact tgtagacctt accatctttt tcaatcttat
     8341 caagacgaag tgaggtagta tcgtacgctt cacccggcaa gccttgtgat accgcaacag
     8401 tttcacctaa aacattacct tctgtatcca cataagatac aagaacatta gcattaaacg
     8461 gaacaaattc ccaatcacca attaaagtaa tatctccatc acctggtgct gtatagccct
     8521 ctgtaagttt agtttcacca tcatttgtgt aacgtgacca accagtaaat ctccactcac
     8581 cagttgcagt tctgacattt tagcaacatc aagaagctcc tgtggtaaag tcataccttg
     8641 cttgctaccg aaaatgtaga taactgtact cttctcttta cgaagagctt cattagctgc
     8701 ttcttcttcg gcacgttttg atctttctgc ttctgcctta accgctatag tttgttcagc
     8761 ctcagctaag attttgttaa tatcgtcaac ttgaattaaa tttgaatcgt taattttcga
     8821 ttcaaaacct gcgattgttg aagccaattc cggatgctgt tgtttaagag tagttagacg
     8881 agctgtagcc tcagctttag ttgcatactt ctgccctctc attgttacct gtgccgatac
     8941 agaagctgta ccaactaaca aggtgcagaa tactgaagct agtccgaaag ccgacttacg
     9001 aagatagtac ttcatttctt tttttgccat ttttattccc ctttaaatat aatggacata
     9061 atgtctccta attatcaatg acagataatt aca
//
LOCUS       DARYYD010000070         9018 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.071, whole genome shotgun sequence.
ACCESSION   DARYYD010000070 DARYYD010000000
VERSION     DARYYD010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9018
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.071"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            27..272
                     /locus_tag="TV188_001721"
     CDS             27..272
                     /locus_tag="TV188_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEL1535048.1"
                     /translation="MGIIWTLIVGALIGAIAGALTKKGGSMGWIANIAAGLIGSYVGQ
                     ALFGSWGLTLAGMALFPSIIGAVIVVIITSFVLNKSN"
     gene            320..901
                     /gene="amaP"
                     /locus_tag="TV188_001722"
     CDS             320..901
                     /gene="amaP"
                     /locus_tag="TV188_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEL1535049.1"
                     /translation="MSKFLKISYSLIGLVLLTVFGGVIAITGDYIRLPIGYQWLHWDM
                     NWLPKFLNPALYYYYFWAAIALFLITVLILLVIIFYPRTYTEIQLAKDKGTLLLKGSA
                     IEGYVAAAIKAAGLMSSPRVTAKLYKRKFKVNVSGQLASRVAVTEQLNGIKEGIETGL
                     TEFFGINRPVHFKVYVKDIADAKQKHSSKRRVE"
     gene            911..1099
                     /locus_tag="TV188_001723"
     CDS             911..1099
                     /locus_tag="TV188_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEL1535050.1"
                     /translation="MAFYERFKYPIIGGLIGLIAAVLLMTFGLFKTLLAIIFIILGVY
                     GGLYAKKTGIIDQLIKRN"
     gene            1112..1651
                     /locus_tag="TV188_001724"
     CDS             1112..1651
                     /locus_tag="TV188_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015632041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1535051.1"
                     /translation="MTETYIKNTTHKEPTSAVRGELTYDDKVIEKIVGLALENIDGLL
                     GVNGGFLANLKDKLVNSDSVRDGVNVEVGKKEVAVDLDIVAEYQKHVPTIFDAIKSVV
                     ENEVKRMTDLEVIEVNVKVVDIKTKEQFEADKVSLQDKVTEVARSTSEFTSKQVDNVK
                     ASVGAGVEKVQEQTEPRVK"
     gene            1689..1886
                     /locus_tag="TV188_001725"
     CDS             1689..1886
                     /locus_tag="TV188_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011528688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEL1535052.1"
                     /translation="MSEEKVNAKLEQAGGKIKEAFGKVTGDKSLETEGKVDQAASKIK
                     EVAADAKDAVKGFVKGLKQDK"
     gene            1896..2384
                     /locus_tag="TV188_001726"
     CDS             1896..2384
                     /locus_tag="TV188_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1535053.1"
                     /translation="MKAKDIKSTLTYDDKVIEKIVGHALEKVSGLLAVNGGFFSNIKN
                     NLVNSDSVRDGVSVEVGSKEVAVDLDIVVEYGKDIPAIVESIKAIVFQNVDSMTHLRV
                     VEVNVNVVDIRTKEEHEAASVTVQDRLTDAASATSQFVAEQADKVKETVSKTTDNNET
                     VE"
     gene            2540..3181
                     /locus_tag="TV188_001727"
     CDS             2540..3181
                     /locus_tag="TV188_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1535054.1"
                     /translation="MTSNKREITNSKYQKIAISVAERIANGEYEVGEKLKSRTTIAST
                     FKVSPETARKGLNILADLKILTLKHGSGAIVLSKEKAIDFLNQYESTHSIAVIKENIR
                     HNIREQEKAMEHLTVLVNEFLMQSQSISKQYPLAPYEIICSQDSEHFGQSIGDLNIWH
                     QTGATIVAIEHDGQFIVSPGPYAVIEKGDHIYFVGNEDVISRMKTFFNVRKGL"
     gene            complement(3298..3846)
                     /locus_tag="TV188_001728"
     CDS             complement(3298..3846)
                     /locus_tag="TV188_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEL1535055.1"
                     /translation="MTTRHTPTKAYLKQALVSLLTEKSFETITVSDLTKKAGVNRGTF
                     YLHYRDKHDMMTHLINDTLDDLYQLLNDPHIFTDTRLVLKEALAYIIDNLPFIAAMAN
                     SSYLNFSQILKDFIYQFLTTIDGFQEIITKHYQIPYHYALEVYLASIESLISYWISHD
                     CQETTDDMTAIILKTVGFEKVI"
     gene            3969..4670
                     /locus_tag="TV188_001729"
     CDS             3969..4670
                     /locus_tag="TV188_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1535056.1"
                     /translation="MSYIEMRSSSKTYQIGETTVKANDEVSFEIERGELVIILGASGA
                     GKSTVLNILGGMDSNDQGQVIIDGKDISTYSKKALTSYRRYEVGFVFQFYNLVPNLTA
                     KENVELAADIVADALDPTTVLNEVGLGGRLEHFPAQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDYQTGKQILRLLQDMAHDKGRTVIVVTHNTALAPIADRVIYMHDGRVTK
                     TVLNKQPLDIDRITY"
     gene            4682..7321
                     /locus_tag="TV188_001730"
     CDS             4682..7321
                     /locus_tag="TV188_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEL1535057.1"
                     /translation="MKQKTLWKDSFRAIKASKGRFLSLLFLMALGSFALVGLKVAGPN
                     MEKTASHYLEEHQVMDLSILASHGFSDRDKQELASLKNARLEYASFVDGAFDHQRKAI
                     RLYSMPQSLSQASLVKGDYPSKASDILLSEALSSRYRLGQIITISLKTKGLLKHRSYR
                     VVGFAHSPEIWSKTNLGVSSAGDGNLYAYAYLHPSAFQQGHNLLRIRYDDLRGLNAFS
                     TQYNERLLQHQAELDQILQDNGQERYEEMLNDLNRSLKDSKVKLEEQRTVLKASEDQL
                     ALLSGHALEQAQTQLKQGQEELAKKEASLLELAEKQRAAMIKPTYTSYSRSTLPGGEG
                     YQTYATSTQSISHVGNIFPVVLYLVAALVTFTTMARYVDEERTNSGLLKAIGYSDWDI
                     TKKFLLYGALAALLGTGLGVLGGTYFLSRLISAILTDALTIGSTQLYFYWSYSVVAVL
                     LALLSAVLTAYMVVRRELFLRPSQLLLPKPPSSGARIWLEHVSFIWRRLSFTYKVTFR
                     NIFRYKQRMLMTVIGVAGSVALLFSGLGIQSSLANSLSYQFGKLTAYDMLVVEAPTAE
                     AHDRQELAQYLKADQIASKKEIYYANLSLKIKDLDNKQTVSLISSDQSTLSPYFSLIG
                     AADRKKLDLPSTGVLISKKLADYYQAHAGDQLELEASNGKRYQLRVSQVIDMTVGHYL
                     FMSKSYYQQVFRDMEASPSYLVTTAKASPSAVKDVASQLLAMPAVQAVSQHSSIVATV
                     TGIVASLDQVMTLLVLLSVLLALVILYHLTNINIAERVRELSTIRVLGFYDKEVTLYI
                     YRETMLLSAVGILIGLWGGSYLHAYIMKVIANDSMSFGRTVDAYVYLVPVGAIVLLLI
                     VLGYMVSYRLRKIDMLEALKSVD"
     gene            7397..7993
                     /locus_tag="TV188_001731"
     CDS             7397..7993
                     /locus_tag="TV188_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEL1535058.1"
                     /translation="MEAMIAAYLADHREKIPLGQVVDCFKGKAVSRKAEAGEFGLINL
                     SDMGQLGIDYHQVRAFHMDRRQLLRYILEDGDVLIASKGTVQKVCVFHKQEREMVASS
                     NITVLRPQRVLRGYYIKFFLESAIGQALLKAADHGKDVINLSTKALLDIPVPVIPLVK
                     QDYLINQYLRGLHDYQRKVNRAEQEWQFIQNEIQKGLG"
     gene            8003..8965
                     /locus_tag="TV188_001732"
     CDS             8003..8965
                     /locus_tag="TV188_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEL1535059.1"
                     /translation="MSLIERTIKMLLATMAAIFLASQLQLSYAISAGIIALLGVLDTR
                     KSSLIVARKRLLSFFLAFAVAVSLFALFGFGLLSIGLYLALTIPLLYQLKIEAGLVPI
                     TVLVTHLMSEQRIDLSILFNELLLFLIGTGLALLVNGYMGSQEHRLRLYHQKIEDSLK
                     AILYRFESFLLEGQGQNEGQMIKELELSLDEALKLVYRERHNTLFYHTNYQVHYFEMR
                     RHQNRLLAQMALNVTQLTSQSRESLLLSHLFHETARQLSEKNSALTLIDDIEQLLEVF
                     RQRELPQTREEFERRAILFQLLQDLERFILLKVEFYRDYKEEQA"
BASE COUNT         2597 a         1565 c         2121 g         2735 t
ORIGIN      
        1 gttttattga attgaggaga tttattatgg gaattatttg gacattaatt gtgggtgcac
       61 ttatcggtgc tattgccggt gcgcttacta aaaaaggcgg atcaatgggc tggattgcca
      121 atatcgctgc aggacttatt ggatcatacg ttggtcaagc tttgtttggc agctggggtc
      181 taacattagc tggcatggca cttttcccat caatcattgg tgctgttatc gttgttatca
      241 ttacttcttt tgtactaaat aaatcaaact aagggcattt ctatcattat agagatggtt
      301 gagtaggaaa gaggttttta tgtcgaaatt tttaaaaatt agctatagtc tcattggctt
      361 agtcctattg acggtctttg gtggcgtgat agccataact ggagattata ttaggctacc
      421 tattggctat caatggcttc actgggatat gaattggctt cctaaattcc taaatccggc
      481 cttatattac tattactttt gggcagctat cgctttattt ctaataacag tgctgatcct
      541 tcttgtgatt atcttttatc cacgcaccta tactgagatt cagctggcta aggataaagg
      601 aaccctgctt ttgaaagggt ctgctattga aggctatgta gcagctgcta ttaaagcagc
      661 agggcttatg tcaagcccaa gagttaccgc taagctgtac aagcgtaaat ttaaggttaa
      721 tgtcagtgga caattagctt ctcgcgtagc tgtcactgag cagctaaatg gcattaaaga
      781 aggaattgag actggtttaa cagaattctt tggtattaat cgacctgtcc atttcaaggt
      841 ttatgtcaag gatattgctg atgctaagca aaagcatagc tctaagagac gtgtagaata
      901 ggagattatc atggcatttt atgaacggtt taaataccct attattggtg gtctgatagg
      961 gctgatagct gctgtattac tgatgacctt tgggttattt aaaacactgc tggcaattat
     1021 tttcattatt ttaggagtat atggcggcct gtatgccaaa aagacaggta ttatcgatca
     1081 attgatcaaa cgtaactaaa ggagatttat catgactgaa acttacatta aaaacacaac
     1141 tcataaagaa ccaacttcag ctgttcgtgg cgaattgacc tatgatgaca aggtcattga
     1201 aaagatcgtt ggcttggctc ttgaaaacat tgatggccta ctaggtgtta atggtggctt
     1261 tttggccaat ctaaaagaca agcttgttaa tagtgattct gttcgtgatg gggttaatgt
     1321 tgaggttggt aaaaaagagg ttgctgttga tttagacatt gtagcagaat accaaaagca
     1381 tgttccaacc atttttgatg cgattaaatc tgtcgtagaa aatgaagtca agagaatgac
     1441 agatttagag gtgattgagg ttaatgttaa ggttgttgac attaaaacca aggagcaatt
     1501 tgaagctgat aaggtcagcc tacaggataa ggtgactgag gtagctcgct caacctctga
     1561 atttacaagc aagcaggtag acaatgttaa ggcatctgta ggtgcaggtg tagaaaaggt
     1621 tcaagagcaa actgagccac gcgttaagta agctaggctg tcaaacgata gaaatagagg
     1681 aaatcataat gtcagaagaa aaggtaaatg caaaattgga gcaagcaggc ggtaaaatca
     1741 aagaagcctt tggaaaggtg actggtgata aatccttaga aaccgaaggt aaggttgatc
     1801 aagcagccag caaaatcaaa gaagtagctg ctgatgctaa ggacgctgtc aagggctttg
     1861 ttaagggcct taagcaagat aaataaggag ttgtaatgaa agcaaaggac ataaaaagta
     1921 cgttgaccta cgatgataag gtcattgaaa aaatcgttgg acatgcttta gagaaggtca
     1981 gtggcttatt agcagtcaat ggtggctttt tctcaaatat caaaaataac ctagtgaata
     2041 gtgactctgt tcgtgatggg gtgtctgttg aggttggcag caaggaagtg gctgttgact
     2101 tagatattgt tgttgaatat ggtaaggata ttccagcaat tgttgagtct atcaaggcta
     2161 ttgtttttca aaatgtcgat agcatgacac atttgagggt cgttgaagta aatgtgaacg
     2221 ttgttgatat tagaaccaaa gaagagcatg aggctgctag cgtcactgtt caagacaggc
     2281 taacagacgc ggcctcagca acctctcaat ttgtagctga gcaagcagac aaggtaaaag
     2341 aaactgtctc taaaaccaca gataataacg agacagtaga ataaaacaca acaactaaaa
     2401 ctcctgttaa tgacatattg tgggctggtg tgatgaccag ctctttttat cagtgcttga
     2461 acaatgttat gctattgtat tctctgtgaa aatgtgattt aatgggaatg gtatcatttg
     2521 ttaaaaagga gtaattatca tgactagtaa taagagagag attactaatt ccaagtatca
     2581 aaagattgcc atttcagttg ctgaaaggat tgccaatggc gaatatgaag tgggagaaaa
     2641 gctaaagtct aggacaacca ttgcttcgac ctttaaagtt tcgcctgaaa ctgctagaaa
     2701 gggtctgaat attttagctg atctgaagat tttgacctta aagcatggga gtggcgccat
     2761 tgtcttgtct aaggaaaagg ctattgattt tctgaaccaa tacgaatcca cccattctat
     2821 cgctgtcatc aaagaaaata ttcgccataa tattcgtgag caggaaaagg caatggagca
     2881 tttaacagtg cttgttaatg agtttctgat gcaaagccaa tcaatcagca agcaataccc
     2941 gctggcacct tacgaaatta tttgtagtca ggattcagag cattttggcc aatccattgg
     3001 tgatttgaac atttggcatc aaacgggagc gacgattgta gctattgagc atgatggcca
     3061 attcattgtt tctcccggtc cttacgctgt tatcgaaaaa ggtgatcata tttactttgt
     3121 cggtaatgag gacgtgattt ctagaatgaa aacctttttt aatgttagaa agggtctgta
     3181 atcacaaaaa aacacagagc tgctttaagg tgatggtgat atcacgatga agtgtctctg
     3241 tgtttttgtg ttatcaggct aaggcttcta agtagcttat agctctgatt gaagccccta
     3301 gattactttt tcaaagccaa cagttttcag gataatagct gtcatgtcat cggttgtttc
     3361 ttgacagtca tgactaatcc agtagctaat cagactttca atactggcta gataaacctc
     3421 aagcgcgtag tgataaggga tctgatagtg cttggtgatg atttcttgaa agccatcaat
     3481 agtggtcaaa aattgataaa taaaatcctt gagtatttgt gaaaaattca aataactgga
     3541 gttagccata gcagcaataa agggaagatt atcaatgata taagcgaggg cttcctttag
     3601 aacgagtcta gtatctgtaa aaatatgagg gtcatttagg agctggtata aatcgtctaa
     3661 ggtgtcattt atgagatgag tcatcatatc atgtttatcc ctgtaatgca gataaaaggt
     3721 gcctctattg acaccagctt ttttggttaa gtcagaaacg gtaatggtct caaagctctt
     3781 ttctgtcaaa agactgacaa gtgcctgctt caaataggcc ttggttggtg tgtgtcttgt
     3841 tgtcatcgac tcatctcctt aagtcaacaa atgctgctta tctgttcttg ttaaagtctt
     3901 gaggacatta tataataagg ctagtataaa atcaacaagg tgttgatata aaggaggtga
     3961 catgatcagt gtcctatatt gaaatgaggt cctcttcaaa gacctaccag attggagaaa
     4021 caactgttaa ggctaatgat gaggtatcct ttgagattga aagaggggag cttgtgatca
     4081 ttttaggagc ctctggtgca ggcaagtcca cagtgcttaa tattttaggc ggcatggata
     4141 gcaatgacca aggtcaggtc ataatagacg gcaaggacat ctcgacctat agtaaaaagg
     4201 cattgaccag ctaccgtcgt tacgaggttg gctttgtttt tcaattttac aatctggtgc
     4261 caaatctgac agcaaaggaa aatgttgagc tggcggctga tattgtggca gatgcacttg
     4321 atccgactac tgtcttaaat gaggtggggc taggaggacg tttggagcat ttcccagcac
     4381 agctatcagg aggtgagcag caaagggtgt ctattgctcg tgccttggct aaaaatccta
     4441 agttgttgct ttgtgatgag ccaacagggg ctttagatta tcaaaccggc aagcaaattt
     4501 taagattgct tcaagatatg gcgcacgaca agggcaggac agttattgtg gtgacgcata
     4561 atactgctct agcgcctatt gctgatcggg tcatttatat gcatgacggt cgtgtgacca
     4621 agacagtgct taataagcag ccgcttgata ttgataggat aacgtattga gaggtgccta
     4681 gatgaaacaa aaaaccttat ggaaggatag ttttcgagca ataaaagcta gtaaggggcg
     4741 ttttttgtcc ttgctatttt taatggctct aggctccttt gccttggttg gcttaaaggt
     4801 ggctggtccc aatatggaaa aaactgctag tcactatcta gaggagcatc aggttatgga
     4861 ccttagtatc ctagcctcgc atggcttttc tgatagagat aagcaagaat tagcctctct
     4921 taaaaatgca agactagagt atgcgagctt tgttgatggt gcttttgatc accagaggaa
     4981 ggctattagg ctttattcta tgccacaaag cctatctcag gccagcttgg tcaagggaga
     5041 ttaccctagc aaggctagcg acattttgct atctgaagct ttatcaagcc gctatcggct
     5101 tgggcaaata atcacgataa gcctaaaaac aaagggattg ctaaagcata gatcctatcg
     5161 tgttgtcggc tttgctcatt ctccagaaat atggtccaaa acaaacttag gtgtttcctc
     5221 agcaggggat ggtaatctct atgcctatgc ctaccttcac cctagtgcct ttcagcaagg
     5281 gcacaatctc ttacgcattc ggtatgatga tttaagaggg ttgaatgcct tttcaactca
     5341 atacaatgaa cgattgctac aacaccaagc agagcttgat cagatcttgc aggacaatgg
     5401 tcaagagcgt tatgaagaaa tgctcaatga ccttaatcgc agcttgaaag atagtaaagt
     5461 taagctcgaa gagcaaagga ctgttcttaa ggcaagtgaa gaccagctgg ctttgctaag
     5521 tggtcatgcc ttagagcaag cgcagactca gctaaagcaa gggcaggaag agttagctaa
     5581 aaaagaagca agcttgctag agttagctga aaagcaaagg gcagcgatga tcaagccaac
     5641 ctatactagc tatagtcgct caacgctgcc aggtggtgag ggttatcaaa cctatgccac
     5701 ctcaacacag tccatatcgc atgttggaaa tatctttcct gttgttttgt atttggttgc
     5761 ggccttagtt acttttacaa caatggctcg ctatgttgac gaagaacgaa cgaactcagg
     5821 cttactaaag gcaataggct attctgattg ggatattacc aaaaaatttc tgctatatgg
     5881 tgccttagct gccttgttgg gcactggatt aggagtttta ggagggactt attttttatc
     5941 tcggctcatc tcagctatcc taacagatgc attgactatc ggctctactc agctttattt
     6001 ttattggagc tatagtgtgg ttgcagtgct tttagccttg ttatctgctg ttttgacagc
     6061 ttatatggtg gtgagacgtg agctttttct cagaccctca caactgttgc tgcctaagcc
     6121 tcctagtagc ggggcaagga tttggctgga gcatgtctcc tttatctggc ggcgtttatc
     6181 ctttacctat aaggttactt ttcgaaatat ctttcgatat aagcaaagaa tgctgatgac
     6241 agtaattgga gtagcaggtt ctgttgcgct cttattttcc ggcttgggca ttcaatcctc
     6301 acttgctaat agcctaagct atcaatttgg caagctgaca gcctatgaca tgctcgtggt
     6361 agaagctcca acagcagaag ctcatgatag gcaggagctg gcacaatatt tgaaggcaga
     6421 tcagattgct agtaagaaag agatttatta cgctaactta tcactaaaga taaaagactt
     6481 agacaacaag caaacagtgt cgttgatttc tagcgatcag agcactctat ctccctattt
     6541 tagcttgatt ggtgctgctg accgaaaaaa gctagacctt ccaagtactg gagtgcttat
     6601 ctcaaaaaag cttgctgact attatcaggc tcatgcagga gatcagcttg agcttgaagc
     6661 tagtaacggt aaacgctatc agttaagagt gagtcaggtt attgacatga ctgttggtca
     6721 ttacttgttc atgtctaaat cttattatca gcaggtattt cgggatatgg aggcttcacc
     6781 atcctatttg gtaacaacag caaaggctag tccatctgct gtaaaggacg tagctagtca
     6841 gctcttagca atgcctgcgg ttcaggctgt gtcacaacac agtagtattg ttgctactgt
     6901 gacagggatt gtggcgtctt tggatcaggt tatgacgctt ttagtacttc tatcagttct
     6961 actagccttg gtcattttgt atcatttgac caatatcaat attgctgaga gggttaggga
     7021 attatcaacg ataagagtct tgggctttta tgacaaggag gttaccttat acatttaccg
     7081 ggaaaccatg cttttgtctg ctgttggtat tttgatcggt ctctggggtg gcagctattt
     7141 gcacgcctat atcatgaagg tgattgctaa tgattctatg agctttggta ggacagttga
     7201 tgcttatgtt tacctagtac ctgttggggc tattgtgctt ttgttgattg tgcttggcta
     7261 tatggttagc taccggctaa gaaagattga tatgctagag gctctaaagt ctgttgatta
     7321 gggtaaaata gtacttgaaa atcgcttaat aatatgctag tattaaaata ctataattta
     7381 atagaaggat acttttatgg aagcgatgat agctgcctat ttggctgatc atagagaaaa
     7441 gataccactt ggtcaggttg ttgattgctt taaggggaag gctgtttctc gtaaggctga
     7501 ggctggtgaa tttggtttga ttaatctgtc tgatatggga cagctaggaa ttgactatca
     7561 tcaggttaga gcctttcata tggatagacg acaactattg cgctatatct tagaggatgg
     7621 agatgtcttg attgcctcaa aggggactgt tcagaaggtt tgtgtttttc ataagcaaga
     7681 aagggaaatg gtagcgtcct ctaatatcac agtgctgcgt cctcagaggg ttttgcgagg
     7741 ctattatatt aagttctttt tggagtctgc tattggtcaa gccttgttaa aggcggcgga
     7801 tcatggaaag gacgtgatta acctatcgac caaggcttta cttgatatcc ctgtaccagt
     7861 gattcctttg gttaagcagg attatttgat taatcaatat ttgcgaggcc tgcatgacta
     7921 tcaacggaaa gtaaacagag ctgagcagga gtggcagttt attcaaaatg aaattcaaaa
     7981 aggcttgggc tagaggtaaa atgtgagctt aattgaacga acaataaaaa tgctattagc
     8041 aacgatggct gcaatctttc ttgcctctca gctacagctg tcttatgcca tatcagcggg
     8101 aattattgcc ctgttaggtg tgctagacac tagaaaatct agcttaattg ttgctagaaa
     8161 gcgtctgctg tcttttttct tagcctttgc tgtggcggtt agtctatttg ccttatttgg
     8221 ctttggtctg ctttccattg gcttgtatct agcgctaacc attcctttgc tttatcagct
     8281 gaaaatagag gcaggtcttg ttcctatcac tgtcttggtg actcacctga tgtctgagca
     8341 gcgtattgat ttgtcaattc tttttaatga gctgttgctg tttttgattg ggacgggtct
     8401 tgcccttctt gttaacgggt atatggggtc tcaggagcat cgcctacgct tgtaccacca
     8461 aaagatagaa gatagcttaa aggctatctt gtaccgtttt gaatcctttt tgttagaagg
     8521 ccaaggacaa aacgagggac agatgattaa ggaattagag cttagcttag atgaggcgct
     8581 aaagctggtt tatcgcgaaa ggcacaatac cctcttttat cataccaatt atcaggtgca
     8641 ttattttgag atgagacgtc atcaaaatag attgttggcg caaatggcct taaatgtcac
     8701 tcagctaaca tctcaaagca gagaaagtct cctgctctcc catctttttc atgagacagc
     8761 tcgtcagctg agtgagaaga attctgcttt gacattgatt gatgatattg agcaattgct
     8821 tgaggtcttt aggcaaagag agctgcctca gactagagag gaatttgaaa gacgggcgat
     8881 tctgtttcag ctgttgcagg atttggagcg ctttattcta ctgaaggtag aattttatcg
     8941 tgattacaag gaagagcagg catagtagct gcttgctgct gtgattaaga gtctggaaaa
     9001 atcattttct aggctttt
//
LOCUS       DARYYD010000071         8640 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.072, whole genome shotgun sequence.
ACCESSION   DARYYD010000071 DARYYD010000000
VERSION     DARYYD010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8640
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.072"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(171..461)
                     /locus_tag="TV188_001733"
     CDS             complement(171..461)
                     /locus_tag="TV188_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535060.1"
                     /translation="MLIPITEYYIEEEYAYALRLMRQMLERQRIATVARLANSQGEAI
                     KKTFKDQIKATASQTKESLQIMEGQLDTAIKGAVRDQLEQVVKKKLPKYNKL"
     gene            complement(442..834)
                     /locus_tag="TV188_001734"
     CDS             complement(442..834)
                     /locus_tag="TV188_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535061.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKKGYQKREDSLSERRH
                     VLDDLINSEYQKMSVFLKRLDLSANAASDFFKELDRLKDQSNAEFHLQRAALEEERAQ
                     STKTFRQEQDQRETELLDMRRAYANTNN"
     gene            complement(816..2105)
                     /locus_tag="TV188_001735"
     CDS             complement(816..2105)
                     /locus_tag="TV188_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535062.1"
                     /translation="MMISDSSYKKLSEQVYNVEPSKAKSNDAPIVLKGNRLIDDKTGK
                     QYRVLLVQDNNNDAHKINDNGMQAMAVAPIVQGDVDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNLDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKRMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKVAREGADEALDHK
                     TVADAKLMEVWSAIDFNAFHELPYYEVQALFASYGITYDRFVRDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDQQLAGEFRAWQTEL"
     gene            complement(2107..2538)
                     /locus_tag="TV188_001736"
     CDS             complement(2107..2538)
                     /locus_tag="TV188_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535063.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKRTEEQQKKDLETSIAKL
                     LVHDYEDVKEVKFTGWGRSRETGSWGTIVVINGENEIGFSFDGLSGLADISGRSYHPD
                     TFKLVEKNSLEEMGPVKYRIKDIEKVSLEGVSITYSREKRS"
     gene            complement(2759..3193)
                     /locus_tag="TV188_001737"
     CDS             complement(2759..3193)
                     /locus_tag="TV188_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535064.1"
                     /translation="MKKSTKAFIALMILIGGLLMVFSLNGKITEEQQKKDLETSIAKL
                     LVHDYEGVKTIKFQGWGHSRETGSWGTTVIINESNQMSFSFSSIKTLEDIGSTRYNPN
                     TFKLVEKPETDSKPRIMDRMNEINATSLAGVTVIYSNNNQED"
     gene            3532..3618
                     /locus_tag="TV188_001738"
     CDS             3532..3618
                     /locus_tag="TV188_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014868551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HEL1535065.1"
                     /translation="MQLMLGFGSFLLSLIGLVVIIVKMSNKK"
     gene            complement(3966..6407)
                     /locus_tag="TV188_001739"
     CDS             complement(3966..6407)
                     /locus_tag="TV188_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011185037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEL1535066.1"
                     /translation="MMIYSLKMQDIFNQAQFQAERFDSPYLETWHILLAMVAVDHSLA
                     AMVLSEFERKIRAEEYEAAAILAMGKSPKEVTSVQFKPQSKALSEILAFAHAICQVIN
                     EHEVGSEHVLFAILLNPDIMASRLLELAGYRLKDSGKGEPRFADLRKAIELNAGYSKE
                     TIKAIHELRKPKKSKSVGTFSEMMKPQSTAGELSDFTRDLTEMARQGLLEPVIGREKE
                     VSRMVQVLCRKTKNNPVLVGDAGVGKTALAYGLAQRIANGAIPYELQDMRVLELDMMS
                     VVAGTRFRGDFEERMNQLIDDIEADGKIILFVDELHTIMGSGSGIDSTLDAANILKPA
                     LSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPSVEDAYQILLGLKPSYEQY
                     HNVTISDTAVHTAVKLARRYLTSKQLPDSAIDLLDEASAMVQSMVKKTQPDFITPLDQ
                     ALLDGDMSKVSALLVKEDKQPKLKPTAVTEDDMLHTLSKLSGIPLEKLTQADSKKYLN
                     LEKELHKRVVGQEMAVSAIARAIRRNQSGIRTGRRPIGSFMFLGPTGVGKTELAKALA
                     ELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTEKVRNKPYAVLLFD
                     EVEKAHPDIFNILLQVLDDGMLTDSRGCKVDFSNTIIIMTSNLGATALRDDKTVGFGA
                     KAIGHDHQAMEKRILEELKKAYRPEFINRIDEKVVFHSLTQENMRDVVKIMVKPLIAA
                     LAEKHISLKFQPSALKYLSEAGYDVEMGARPLRRTLQTEVEDRLAELMLSGELSSGQS
                     LKIGVSRGKLAFDIA"
     gene            complement(6407..6868)
                     /locus_tag="TV188_001740"
     CDS             complement(6407..6868)
                     /locus_tag="TV188_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEL1535067.1"
                     /translation="MPTKNTSDSIEEYIKELLAQSGIAEIKRSMLADSFQVVPSQINY
                     VIKTRFTESRGYEVESKRGGGGYIRIAKVHFSDKHHLIGTLIASIDDCLSEQAFTDSI
                     QLLFDEQLLTEREGNIILAVASNDVLGHQAPEIRARMLYRLLQRIDRKGSN"
     gene            complement(7038..7241)
                     /locus_tag="TV188_001741"
     CDS             complement(7038..7241)
                     /locus_tag="TV188_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HEL1535068.1"
                     /translation="MAQGTVKWFNAEKGFGFISTENGQDVFAHFSAIQSDGFRSLDEG
                     QRVTFDVEDGQRGPQAVNITKLS"
     gene            complement(7493..7705)
                     /locus_tag="TV188_001742"
     CDS             complement(7493..7705)
                     /locus_tag="TV188_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1535069.1"
                     /translation="MLTYDEFKQAVDDGYITGDTVAIVRKNGQIFDYVLPGEKVQPWE
                     VVTEEKVENVLRELDWRSVKSRSKLL"
     gene            complement(7901..8416)
                     /locus_tag="TV188_001743"
     CDS             complement(7901..8416)
                     /locus_tag="TV188_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535070.1"
                     /translation="MKSKKLVFGQIDLNMCRDFDLVQALDYDFKEKKLYNKGRGFAIV
                     LVSIQNLTFAIPLRSNIPKKYQLKYKLRDSKKYGCVEGLDIGKALVVEDPKYILNRTF
                     KLREQVDYFKIVDNDILIVNKLIKAIIDYNQAVANSDQHKLTDPKRFKFSTFPNYTDR
                     LKSITDADYLR"
BASE COUNT         2473 a         1973 c         1504 g         2690 t
ORIGIN      
        1 tcagtacact ggtcctctct cgtctttagc tatcggtcac tctgtataca attatcccct
       61 tttaaaaata acaggacaaa agctctggag gctgatcgcc ttttttgatc atacttgctt
      121 ggtaggtatt gattgaaccc ctacggtctc ttataaatga caccatttga ctatagcttg
      181 ttgtattttg gcagcttctt ctttacgacc tgctccagct gatctctgac cgctcctttt
      241 atggccgtat ctagctgccc ttccatgatc tgaaggcttt ccttagtttg gctggcagtc
      301 gctttgatct ggtctttaaa cgtttttttg atcgcttcac cttggctgtt cgcaagccta
      361 gccactgtgg caatcctttg acgctccagc atttgacgca ttagcctcag ggcataggcg
      421 tattcttctt cgatataata ctcagttatt ggtattagca taagctctcc tcatatctaa
      481 taactctgtc tctctttgat cctgctcttg acgaaaagtc ttggttgact gtgctcgctc
      541 ctcttcaaga gctgcccgct ggaggtgaaa ctctgcgttg gattgatcct ttaagcgatc
      601 tagttccttg aaaaaatctg acgcagcatt ggcagatagg tctaaacgct tcaaaaaaac
      661 actcatcttc tggtactcag agttgatcaa atcatctaag acatgtcttc tttcggataa
      721 gctgtcttca cgcttctgat agcctttttt ctggcgcaga aagtcctgct cggcatcatc
      781 catctcccgc agcttacgat agatagccac ttcctctaca attctgtctg ccatgctcta
      841 aactctcctg ctaactgttg atccgtttca agcttgctat caataactgt ctgaatatct
      901 ctattcaggt tttcaaagtc tgtggccaag gctgacagct tgctgacctt ggattgagta
      961 tagtcctgaa agtctcggac gaagcggtca taagtgatcc cataagaagc aaacaaggct
     1021 tgcacctcat aatagggcag ctcatgaaaa gcgttaaaat caatcgccga ccacacttcc
     1081 ataagctttg cgtcggcaac cgttttatga tccagtgcct catcagcccc ctctcgagca
     1141 accttagcca tggacgagcc taggatcatt ccctgtgccg catctaaaaa gagctcctca
     1201 gaactactga tccccttacc ggtagactgc cagtgttttt tgagctgatt gtagcttgac
     1261 atacgctttt ttgaggcaag gacagttaaa taggcccgac tcacaaggta ttgtgttcca
     1321 atgagcttac cgtctctatc tacaatctga cccttttgat taaaacgata agctcctaaa
     1381 tcgtgataat acaaggggtt ggctgataag agcatagcat cgacattccg agaaatagcc
     1441 aaatcatcag ttccaaaata ggcaccaaaa ttgccaatgc catcaaaatt aatgcggaaa
     1501 ttattgtaca tattgctatt agccttaacc catgtgatag cttcagctga catgccgcga
     1561 acagggtctg gaccattaaa ggttgttgct gggatcttat gttctgcggc gactattagt
     1621 gctagataag ctccgagaga gtgacctgtg gttgttaagg cagaatgagg gtactttctt
     1681 ttgacttgtt gataaaactt ttgagcagat cgtaattggt tttcggcaat aacaaaattg
     1741 ccgccatcaa gattgccgct gactaaatca tcttgattgc cccgaatgag cagctgccaa
     1801 tccgtatcaa gatctctgga atccgcagca tttgtccctg cataggcaat cacaacctgg
     1861 gaggtatcga catcaccttg aacaataggg gctacagcca ttgcttgcat accgttgtca
     1921 ttgattttat gggcatcgtt gttattatcc tgaactaaga ggactcggta ttgcttaccc
     1981 gtcttatcat cgataagacg atttcccttt aaaacaatag gggcatcatt tgacttagct
     2041 ttactaggtt cgacattata gacctgttct gacaacttct tataactact atcggatatc
     2101 atcatattaa ctccttttct cacgagaata cgtaattgac actccctcta aagaaacttt
     2161 ttcaatgtct ttaattctat atttcacagg ccccatttct tccagactat ttttctcaac
     2221 taacttaaaa gtatctggat gataagagcg cccactaata tccgctaatc ctgacaaacc
     2281 atcaaacgaa aagcctattt cattttctcc atttataact actatcgttc cccacgaacc
     2341 tgtttcccga gaacgtcccc agcctgtaaa cttaacttct ttgacatctt catagtcatg
     2401 aaccagcagt ttagcaatac tagtttctaa atcctttttt tgttgttcct ctgttctttt
     2461 gccattcaaa ctaaaaacca taagcagccc tcctattaga atcattaaag caataaaagc
     2521 tttggtcgac tttttcatga aagttctcct ttcaatttct aataatagta tacaataaaa
     2581 atgagtaaaa aataaagcta aacagttttt ctataatgtt atctgttata agttaaattc
     2641 tcctgctaat aatctttcca ttaaaacaat agggacatca ttaaatttag ctttccttag
     2701 ttcgatatta taggtctgtc ttgctaactc attatagcta ctatcggata tcgccatatt
     2761 aatcctcctg attgttattt gaatagataa cagtaacacc tgcaagagag gtcgcattaa
     2821 tctcgttcat cctatccata attcttggtt tagaatcagt ttcaggtttt tctaccaatt
     2881 taaaagtatt gggattatat cttgtgcttc ctatatcttc taaagttttt atactagaaa
     2941 aagaaaaact catttgatta ctctcattaa taatcaccgt cgttccccac gaacccgttt
     3001 cacgagaatg tccccatcct tgaaatttaa tggttttaac cccttcatag tcatgaacaa
     3061 gcagcttagc aatgctggtt tccaaatcct ttttttgttg ttcttctgtg attttaccat
     3121 tcaaactaaa taccataagc aaccctccta tgagaatcat taaagcaata aaagctttgg
     3181 tcgacttttt catgaaagtt ctcctttcaa tttctaataa tagtatacaa taaatcagaa
     3241 gtcatagaat aaccatattc aatttttatg tcgtattcga taaaaaatat accatctcaa
     3301 caaacaatcg cttaaaaacg attttagggt atatttcttc cctgcaagca aaggacacaa
     3361 aaaagccatc tgaattttca acatcagaca gctatttcgt atgactatgg tataatggtt
     3421 tctgcagaaa agttaaggcg gtggctctaa tttctgaaag gtggtggtgc ttatgactgt
     3481 aagtgctaaa atccaaagag aaaggagcga atattgtccg tttacgaggc aatgcaactc
     3541 atgcttgggt tcggtagttt tctactttca ctcattggct tagttgttat tatcgtaaaa
     3601 atgagcaata aaaaataacc gtctaacttt agcgagtaac ggttattttt taactaaaaa
     3661 caagctaccg tcttaaacgg ttctgcattg ggtagttgtt ttgagcaact gtcctttttc
     3721 tattttcatt atatctcagc taagaaaaat agtcaaatga gatactattt tggcagctaa
     3781 attggtagct aaatcttcaa aatacctatt tttcgctaaa ttcgattaaa attaaatcct
     3841 atctgtctgc tacgctttaa actctcactc tagtacttca tcaccatacg acaaaaagag
     3901 cctgagaaac tttttgtctc agactctctc aaagctctta gcttaatatc aagcaaagtc
     3961 atgcattaag cgatatcaaa agctagtttt ccacgtgata caccaatctt gaggctttga
     4021 ccgcttgata actctcctga cagcattaat tctgctaacc tgtcctcaac ctctgtttgc
     4081 aaggtgcgac gaagtgggcg agcgcccatt tcaacatcgt aaccagcttc agacaagtac
     4141 ttgagagctg atggctggaa cttaaggcta atatgctttt ctgccaaggc tgcaatcagc
     4201 ggcttaacca taattttcac cacatcacgc atgttttcct gtgttaggct atggaagacc
     4261 accttttcat caattctgtt gataaattca ggccgataag cctttttcaa ttcctctaaa
     4321 atacgctttt ccattgcttg atggtcatga ccgatcgctt tagcgccaaa tccaaccgtc
     4381 ttatcatctc ttagagcagt tgctcctagg ttgctcgtca tgataataat cgtgtttgaa
     4441 aaatcaacct tacatccacg actatctgtt aacataccat catcaaggac ctgcagcagg
     4501 atattaaaga tgtctgggtg agccttttca acctcatcaa aaagaagaac ggcataaggc
     4561 ttatttctaa ccttttcggt tagctctcct ccctcatcat agccaacata gccaggagga
     4621 gccccattaa gacgggaggc tgcaaatttt tccatgtact cagacatatc aaaacgaata
     4681 agggctgact catcatcaaa gagtaattcg gccaaggcct ttgctagctc tgtttttccg
     4741 acaccagttg gaccaagaaa cataaaggag ccaatcggac gcctgcctgt gcgaatgcct
     4801 gactggttac gacgaatggc tcgtgcaata gcagaaacag ccatttcctg accaacaaca
     4861 cgcttatgca attccttttc cagattcagg tattttttac tatccgcctg agttagtttt
     4921 tctaggggaa tacctgatag cttgcttaag gtgtgtaaca tatcatcttc agtaactgct
     4981 gttggtttta gctttggttg cttatcctct ttgactaaaa gggctgacac cttgctcata
     5041 tcaccatcaa gcagggcttg atcaagcggt gttataaagt caggctgcgt ctttttaacc
     5101 atactttgca ccatcgcact ggcttcatca agcagatcaa tcgctgagtc tggaagctgc
     5161 ttacttgtca aatagcgccg agccagcttc acagcagtat ggacagctgt atcagagatt
     5221 gttacattat ggtactgttc ataggaaggc ttcaagccaa gcaaaatctg ataagcgtcc
     5281 tcaacactag gctcctcaat caatatcttg gcaaagcgac gagaaagggc tgcgtccttt
     5341 tcaatgtgct tttgatattc ctcttgagtt gtagcgccaa ccatatgcag ggtaccgcga
     5401 gaaagggctg gctttagaat attagcggca tcaagtgtgc tgtcaatacc acttcctgat
     5461 cccataatgg tatgtagctc atcgacaaac aaaatgatct taccatctgc ttcaatatcg
     5521 tcaatgagtt gattcatgcg ctcttcaaaa tccccacgaa aacgggtacc tgcaaccaca
     5581 ctcatcatgt caagctccaa gacacgcatg tcttgtaatt cataaggaat ggctccatta
     5641 gcaattcgct gcgctaagcc ataagctaga gcagtttttc cgacacccgc atcaccaaca
     5701 agaacaggat tatttttcgt cttacgacaa agcacctgaa ccatacgtga cacctctttt
     5761 tctcgtccga tgactggctc taataagccc tgtcttgcca tctctgtcag gtctcttgta
     5821 aagtctgata gctcaccagc tgtactctgt ggcttcatca tttcagaaaa ggtgcctact
     5881 gatttactct ttttaggctt acgcaactca tgaatcgcct taatagtttc cttgctatag
     5941 ccggcattta gctcaatagc cttacgtaaa tccgcaaacc taggctctcc cttgccagaa
     6001 tccttgagcc tgtagcctgc caattctaac agacgactgg ccataatatc cggattgagc
     6061 aaaatagcaa agagtacatg ctctgagcca acctcatgct cattgataac ctgacagata
     6121 gcatgagcaa atgctagtat ttctgataag gccttggatt gtggcttgaa ttggacagaa
     6181 gtcacctctt tgggactttt tcccatggct aaaatagcag cagcctcata ctcttcagcc
     6241 ctaatctttc gttcaaattc gcttaacacc atggccgcta aggaatggtc aacagctacc
     6301 atagctaata aaatatgcca ggtctcaagg taaggactat caaagcgctc tgcttgaaat
     6361 tgagcctgat taaaaatgtc ttgcatcttt aatgaataaa tcatcactaa ttgcttccct
     6421 ttctatcaat tcgttgcaat aggcgataaa gcatacgagc acgaatttct ggtgcttgat
     6481 gtcccaaaac atcattagaa gctacagcta agataatgtt tccttcgcgc tctgttaaca
     6541 gttgctcatc aaaaagcagc tgaatcgaat ctgtaaaggc ctgctcgctt aaacaatcat
     6601 caatagaagc gatcaacgta ccaatcaggt ggtgcttatc cgaaaaatga accttagcaa
     6661 tacgaatgta gccaccacca ccacgcttac tttctacctc atagcctctg ctttctgtaa
     6721 aacgggtctt gatcacataa ttaatctggc ttggtactac ttgaaaggaa tccgccagca
     6781 tggagcgctt gatctctgcg attcctgatt gggctaacaa ttctttgata tattcttcga
     6841 tactatcgga agtatttttt gttggcatgc cgtcactcct ttgctaaaac gattcatttg
     6901 ctgctttaag cctttatttg actaaaactg actaacatta tatcaaatag cagtcactaa
     6961 aagcaaatgg aaatcactag aatgtaaaag gacaggtgct atcaacaaca cccatcccct
     7021 attatctgct cactagatta agacaattta gtgatattta ctgcctgagg accgcgctgt
     7081 ccgtcttcaa catcaaacgt caccctttgt ccctcgtcta acgatctaaa gccgtcagac
     7141 tggattgctg aaaaatgtgc aaaaacatct tgaccatttt cagttgaaat aaagccaaag
     7201 cccttttcag cattaaacca cttgactgta ccttgtgcca tagtcatcca cttcctttct
     7261 ataacgcatt tgtaaacata gagagaaata aagatgccaa aacacaacta ctaattcaaa
     7321 aactaattta ctcgctcagt gtaacacgaa tggcagccac tgtcaacaca tacccctcac
     7381 aatgacagct tttctactcc acctgctaaa atgtaaaaaa gcaaagtcat gctgaccttg
     7441 ctttaacaat ctaaggcggt agacggattt tagatgcatt gatatcagtg ctttagagta
     7501 actttgaccg acttttgacc gaccgccaat ctaactccct cagcacattt tctacttttt
     7561 cctcggtcac cacttcccaa ggctgcactt tctcccctgg caacacataa tcaaatatct
     7621 gtccgttttt acgcacaatc gctactgtgt ctcctgttat atatccgtca tcgactgctt
     7681 gcttaaactc gtcgtatgtt aacataaata cctcctacct tattattcgt aaaaagtcta
     7741 gtttaatgga ctaattttaa caagtccgtt ataacggata tgccaatgtg tgaatacatg
     7801 tgtgtgaaac acaaaaaacc gcccagaaat aatctgagcg gttgattttt attttggcta
     7861 attcttacta tggtaattgg ttcatgattg tgcgagggtg tcaacgaaga taatcggcat
     7921 cggtaatgct ttttaatctg tcggtatagt ttgggaatgt agagaatttg aaacgtttag
     7981 gatctgttaa tttatgttga tcactattag ctacagcttg attataatct atgatagcct
     8041 ttatcaactt gttaacaata agtatatcat tatcaacaat cttaaaataa tcaacctgct
     8101 ctcgtaattt gaacgttctg tttaaaatat attttggatc ttcaaccact agagctttgc
     8161 caatatcaag cccctctacg catccgtatt ttttagagtc tcttaattta tattttagtt
     8221 gatatttttt aggaatatta cttctcaaag ggattgcaaa agttagattt tggatactta
     8281 ccaacacaat ggcaaaacct cggcctttgt tatatagctt cttctcttta aaatcatagt
     8341 ctaaagcttg taccaaatcg aaatctcgac acatgtttaa atcaatctga ccgaatacta
     8401 attttttact cttcattatt tgccttctaa aaataaaaaa tcctaccaac tgggtattgg
     8461 taggacgcat tgccaacggg atacttctgt taacgagcgc gtccctccgc cccctcattg
     8521 ccaaaatggc gagagtttaa cgacatggaa aggtcggaac atagagataa tgcttttact
     8581 atttatgttc atttacatta ttacataata tgttgcattc gtcaaatata gaatctttaa
//
LOCUS       DARYYD010000072         8607 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.073, whole genome shotgun sequence.
ACCESSION   DARYYD010000072 DARYYD010000000
VERSION     DARYYD010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8607
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.073"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(262..465)
                     /locus_tag="TV188_001744"
     CDS             complement(262..465)
                     /locus_tag="TV188_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin BlpN"
                     /protein_id="HEL1535071.1"
                     /translation="MTHYYQIKEEELNDICGGNPAGAAVVGGLTCAVGGIKLGSRIGP
                     WGAVIGGVGSAAVCGYLAYKASS"
     gene            complement(482..736)
                     /locus_tag="TV188_001745"
     CDS             complement(482..736)
                     /locus_tag="TV188_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1535072.1"
                     /translation="MNTTLMKQFNIIDADKLAHIEGGKNNWQANVWEGGTAAVSGWGL
                     GTAICAASGAGAPFMGACGYIGAKFGVSLWAGVTGATGGF"
     gene            complement(1478..1774)
                     /locus_tag="TV188_001746"
     CDS             complement(1478..1774)
                     /locus_tag="TV188_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1535073.1"
                     /translation="MLTQEEILNKVYNLILDPTLTSEERVILVRFKDRVGESSNFDRE
                     VMMLSESLRQLAVKQIRVETMSVEMAKFYKEISTYKECDKQLGRGLISLGVIRR"
     gene            complement(1781..2029)
                     /locus_tag="TV188_001747"
     CDS             complement(1781..2029)
                     /locus_tag="TV188_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="garvicin Q family class II bacteriocin"
                     /protein_id="HEL1535074.1"
                     /translation="MNMTLMKQFNIIDADKLAHIEGGGKGICKFVMSGSNGYACRYSN
                     GEWGYIVTKSNFEATKDVIVNGWISSLGGGYFHPGYRG"
     gene            2289..4445
                     /locus_tag="TV188_001748"
     CDS             2289..4445
                     /locus_tag="TV188_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEL1535075.1"
                     /translation="MTLFYKRTFVSQIDARDCGVAALASIARYYGSDYSLAHLRELAK
                     TNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMADVPYPLIVHVNKEGKLQHYYVVY
                     KSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
                     LIFKQRTLIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYI
                     LQQLMSFSRDYLLTVLSQRLTIDVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSI
                     IDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYTIIICAFIKPFEQMN
                     HDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQ
                     ATLKQGAQLILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQ
                     AAKVANNRLNEVYLVESEFKASQALYDLSLLQGDIQFEAVSYRYGFGKDTLSDITLTI
                     KQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQYINYLPQ
                     QAYVFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSG
                     GQKQRIALARALLTQAPILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIA
                     ERTDQIVVLNQGQIIETGSHQELMKQGGFYYHLFSE"
     gene            4456..5814
                     /locus_tag="TV188_001749"
     CDS             4456..5814
                     /locus_tag="TV188_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEL1535076.1"
                     /translation="MNPNMFKSAEFYQRRYHHLTTFLTIPLALLLTFLILFSCFVYKE
                     ITVTSYGEITPTQVIATVQSISNNPIIANHLTNNQPIKQGDSIIQYAKDLEESQKQVL
                     EKQLATYEKQKSSLNTLLLSLKQGQNLFQNDDQFGYVNTFNHFMSQAQDIDLGFSKIK
                     AETSQQAQLIQDSIVAINQQINSLSQQISDYEELRSAIINQSDSLSSNNPHQATLDAY
                     LSQSQANQETATNQLLFQIDQNLLNLKTSIDSLYRQRANLHQSTSYDNSLNTKLEILR
                     TQFLITASQQLTDVNHHITELKAQLEQATLQVNNLVIKASKSGIVQLNSAFEGKISIP
                     IGHDIAYIYPSLKQTKQALLTYYVSSESVSLLKKNQVVRLALDRHGNQPIVITGTIKT
                     IDELATKTKQGNLFKVTAKLTLSEKESTTIQYGQQGRVISVIAKKTFFDFYKDKLFKV
                     TE"
     gene            5914..6045
                     /locus_tag="TV188_001750"
     CDS             5914..6045
                     /locus_tag="TV188_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1535077.1"
                     /translation="MDKPTRQPKFQELTPSQLTQITGGGWLEGLQKVFNVSKPKLLK"
     gene            complement(6167..7501)
                     /locus_tag="TV188_001751"
     CDS             complement(6167..7501)
                     /locus_tag="TV188_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HEL1535078.1"
                     /translation="MKLILFFLEMTTSIGLSLVLFSKISGRQLTWLEVAFSTFLRIGF
                     AVFFTIANHVADISLLNYWSLPIYMVVISWLLLRPLSKTLLIFYGLFPITLWSLWYRL
                     LGFFILPLFKLDYHLTNDGFWGIFTDIVSTLMVFLFLRWLRYDFRALRINLLSDRDKR
                     ILGVTNWSMVSYYFLIQLLAYLEYELAVDTYAYRQCMMLGYWIIFMGTVSRLDRSLRD
                     TLQERLTFQRELQLANIESYSRQIEELYREVRGFRHDYSNLIATLKFGIDNDSMSIVR
                     SVYQSVFKDSNKRFRKQKYDVGRLIHVTDTALKSLLAAKFSQALESGISVSLEVPEDI
                     SPQGMELIDFLTIVSILCDNAIEAAVEASSSKITISYFTLDNKQLFMIENTTKEEKID
                     LSFLYDFGVSTKGDNRGVGLYNAMEIINRYPNVMIKTISQNHVFGQTLELRL"
     gene            complement(7501..8250)
                     /locus_tag="TV188_001752"
     CDS             complement(7501..8250)
                     /locus_tag="TV188_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1535079.1"
                     /translation="MRVVILEDDMIQQRYLEKLIKELEVKHQLLFQGLDCFGRPHQLL
                     SAIKKNCGQQLFFLDIEIKNENKKGLEVARQIRQINPDAMIVFVTTHSEFMPLAFQYQ
                     VSALDYIDKELPQTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
                     IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINHRNVVRVDKIERV
                     VYFRNGSSCLIARSKMNSVLTTIENLHRGDN"
BASE COUNT         2911 a         1880 c         1308 g         2508 t
ORIGIN      
        1 atatgacagg ctacaggagt atcattcttt aaatgttaac aattgctaaa atttcgatat
       61 taggtctatc aatatcataa tataaaggat aaaaagaaac attaagttgt catgagctaa
      121 aaataacaaa aaaaagctat ttatcgttga tatatcaaca atgtcattat ttttatctaa
      181 acctctcaca gatctataga taaaataaat ttgaaaggtg aaaataacta tagtaaatat
      241 atatttcaga ttcatatcat attatgatga agccttatag gctaaataac cacaaacagc
      301 tgcacttcca actcctccga taacagctcc ccaaggtcca atcctacttc ccaactttat
      361 acctccaaca gcacaggtca aaccacctac tactgctgca ccggcagggt tccctccaca
      421 aatgtcgtta agttcttctt ctttgatttg ataataatga gtcataaaaa acctctcttg
      481 attaaaatcc acctgttgct cctgttactc ctgcccacaa tgatacgcca aatttggctc
      541 caatgtaacc acatgctccc ataaatggag caccggcacc acttgcagca caaatagctg
      601 tccctaaccc ccagccacta acagcagcgg taccaccttc ccaaacatta gcttgccaat
      661 tattctttcc accttcaatg tgagcaagct tgtcagcgtc tataatatta aattgtttca
      721 ttaatgtcgt attcatcgtg aatacctcct atatttattt tttgtctgct gcaactgaca
      781 aacccagtat agcagataaa caatcgcttt cagtatttaa gtcttaaaat gtcgtcgaaa
      841 cgtcttgaat ggtaatacga aaaccgttaa caccaattca gtgaaaattc ctaataccca
      901 taacaaatat gagaaagctg tcttaattgc ttcaaaagct gagtttcctc ctttgacggc
      961 tgaaggctct atgctgtaat gacaaatagc ccaatcttaa atgactattt tatttttcca
     1021 gatagcaata catcatcaac agctgatgaa aataatacat ttgtggcctc agcttactaa
     1081 cttaagcctc tagaaataag gaaaagcaac tgatttgata gctaatagcg cagataatat
     1141 ttcttttcca agctcaataa gactcaaaaa taagttcttt gtaagaaaaa ataaatcact
     1201 aaccaaatga gataagctta ttgcccttgc aattatctca agctacttct tgtccgaaac
     1261 caccctagat agttaactac cacaaaacaa taggtatcag ctttaaactg atacccattg
     1321 ttatatcctg cgattagcca atcaactcaa tcgttactta ctttaccttc agctagccat
     1381 ctcacaaaat agcattgaca accttttcat gtcatttggc ctattgtgac tcaacaaaac
     1441 aataacgcca atacaacgat aaggtatgag cgttttatta tcgcctaata actcccaatg
     1501 atattaggcc tctacctagc tgtttatcac attctttgta agtagagatt tctttataga
     1561 atttagccat ttctacactc attgtttcaa ctcttatctg cttaacagct aattgacgca
     1621 gagattcaga tagcatcatc acttctctgt caaagttact tgactcccct actctatctt
     1681 taaatcttac cagaatgact cgctcttctg atgttaaggt tggatctaaa attaaattat
     1741 aaaccttatt tagtatctct tcttgcgtca acatacccaa ctaccctcta taccctggat
     1801 ggaaataacc acctcctaaa gaggatatcc aaccattaac aataacatct ttagttgctt
     1861 caaaattact tttagtaaca atatagcccc attcgccatt gctatatcgg caggcatacc
     1921 cattagaacc agacattaca aacttacaaa ttcctttgcc gccaccctca atgtgagcaa
     1981 gcttgtcagc gtctataata ttaaattgtt tcattaatgt catattcatc gtgaatatct
     2041 cctatattta ttttttacct gttgcaagca acaaacccag tatagcagat aaataactgc
     2101 tttcagtatt taagtcttaa aatgtcgtcg aaacgtcttg aatggtaatg tcgcaactga
     2161 ttaaaaaaga gtgttaatat cattattccc atttaagacg tttcaacgac tattcaagac
     2221 tagctcagtt tttttctgag cttttgtggc acaatagagt cgttacaaca gagaaaggaa
     2281 gccaaccaat gacactcttt tataaaagaa cctttgtatc acaaatagat gccagagatt
     2341 gtggcgtagc tgctctagcc tcaatcgcaa ggtattatgg ttcagattat tcattagctc
     2401 atttgagaga attagcaaaa accaataagg aagggacaac agccctcggt attgtcatgg
     2461 ctgctaagga aatgggattt gaaaccagac ccattcaagc ggatatgacc ctctttgaca
     2521 tggcagacgt gccctatcca ttgatcgtcc atgtcaataa agaaggaaag ctacagcact
     2581 actatgtggt ctacaaatct aaaaaagact atcttatcat tggtgatccc gatccaatgg
     2641 tcaaggtcac aaaaatgtcc aaggaacgct ttgcttcaga atggacaggt gtcaccatat
     2701 gtcttgctcc taagccaaat tataaaccac ataaagacca aaaaaatgga ctattaggct
     2761 tctttccgct tatttttaaa cagcgaaccc ttatatttta tatcgtgtta gcttctgtct
     2821 tggtaacggt cattaatatt gctggttcat actatctcca ggggatttta gacgagtata
     2881 ttccaaatca gctgaaatct accttaggga ttgtatcaat tggtctcatc attacctata
     2941 tactccagca gctaatgagc ttttctagag attatctttt aactgtcctt agccaacgtc
     3001 ttacgattga tgtgattctg tcctatatcc gccatatttt cgaattgccg atgtcctttt
     3061 ttgcaacacg tcgaacaggt gaggtaacct cgcgctttac agatgctaac tctattattg
     3121 atgcactcgc ttcaaccatt ttatccctct ttctagacct ctctatatta gctattgtcg
     3181 gaagtgttct tttggtgcaa aatagcaggc tttttctgct atctctgatt tctatcccag
     3241 tatataccat tatcatatgt gcctttataa agccgtttga acaaatgaat catgatgtga
     3301 tgcaaagcaa tgccatgcta agctctgcta ttatcgaaga tatcaacggg atcgaaacca
     3361 taaaatcact aaccagtgaa gaaaaccgtt accaaaaaat tgacagcgac tttgtggatt
     3421 accttgataa gtcttttaag cttagtaaat ataccatctt acaagccaca cttaagcaag
     3481 gagcgcagct aattctgaat atcatcattc tttggtttgg ggctcaactg gtcattaatg
     3541 gtaaaatttc aatcgggcaa ttaattacct ttaacacact tcttgcctat tttacaaccc
     3601 ctttagaaaa tatcattaat cttcaaacca agctccaagc agctaaggtt gccaataatc
     3661 gtctcaatga ggtctatctt gtagagtccg aatttaaagc ctcgcaagcc ttatacgatt
     3721 tatcgctctt acagggtgac attcagtttg aagctgtttc ctacaggtat ggctttggca
     3781 aggatacatt atcagatatt acattaacca ttaagcaggg agcaaaagta acccttgttg
     3841 gtgtcagcgg ctcaggaaaa acaaccctag ccaagatgct cgtcaatttc tttgaacctt
     3901 ataaaggacg tataaccatc aaccaaaacg atctcaagac cattgataaa aagaatcttc
     3961 gacaatacat caactacctt ccacaacaag cctatgtgtt taatggatct atcttagaaa
     4021 atctaacctt gggagccaag caaggcatca gccaggaaga cattcttaac gcctgtgaga
     4081 ttgctgacat tcgtcacgac atcgagcaaa tgccaatggg ataccaaacc gagctctctg
     4141 atggggctgg cttatctggc ggacaaaaac agagaattgc acttgctaga gcattactaa
     4201 cccaagctcc tatactagtt cttgatgaag caaccagcgg acttgacata ctgacagaaa
     4261 agaaaatcat tgaccgtctc atgaacatga cagacaaaac gattattttc gttgcccacc
     4321 ggcttagtat cgcagagcgc actgatcaga ttgttgttct taatcaaggg caaatcattg
     4381 aaacaggcag ccaccaggaa ttaatgaaac aaggtggatt ttattaccac ctatttagtg
     4441 aataaggaga caatcatgaa tcccaatatg tttaaaagtg cggaattcta ccaaagacgc
     4501 tatcatcatt tgacaacatt cttaacaatt cccttagccc tcttgttgac ttttcttatc
     4561 cttttttctt gctttgttta taaagaaata acggtaacgt cctacggaga aatcactccc
     4621 actcaagtca ttgcaacagt ccaatctatt agcaataatc ctataattgc gaaccatctc
     4681 accaataacc agccaatcaa acaaggagac tctattattc aatatgctaa agacctagaa
     4741 gagtctcaaa agcaggtact tgagaaacaa ttagctacct acgaaaagca aaaaagcagc
     4801 cttaatactc tattgttaag cttaaaacaa ggccagaacc tttttcagaa cgatgatcaa
     4861 tttggttacg tcaatacctt taatcatttc atgagccaag cccaagatat tgaccttggt
     4921 ttctcaaaaa taaaggcaga gaccagccag caggcccagc tgattcagga ctctattgtt
     4981 gctatcaatc agcaaataaa tagtctttct caacaaatat cagactatga agagcttcga
     5041 tctgcgatca ttaaccaatc cgatagtcta tcctccaata acccacatca agccaccctt
     5101 gatgcctatc tctctcaatc tcaagcaaac caagagactg ccaccaatca gcttctattt
     5161 caaatagacc aaaatctttt aaacctaaaa acctctatag atagcctcta taggcaacgt
     5221 gctaatctac atcaatctac cagctatgat aatagcctca acacaaagct agaaatactc
     5281 cgaacacagt ttttgataac agcctctcag cagttaacag atgtcaatca tcatattact
     5341 gagctcaagg cgcaattgga gcaagccact cttcaggtaa acaatctggt gatcaaagcc
     5401 tcaaaaagtg gcattgttca gctcaatagt gcttttgaag gcaaaattag tatcccaatc
     5461 ggtcacgata ttgcctacat ttatcctagc ctcaaacaaa caaaacaagc cttgctcact
     5521 tactatgtca gctctgaatc tgtttctctc cttaagaaga accaggttgt caggctagct
     5581 ctagatagac atggaaatca accgatagtc attacgggaa ccattaaaac cattgatgag
     5641 ctagcgacca aaaccaagca gggaaatctt tttaaggtta cagccaaact aacactttct
     5701 gaaaaagaaa gcactactat tcaatatggt cagcagggac gagtgataag tgttattgcc
     5761 aaaaaaacat tctttgactt ttataaggac aagctcttta aagtgacaga ataaccattt
     5821 agcgcttttc aacgaccatt taggacatag agtacaacaa agagtcaaga taagctataa
     5881 taacatagac agtatttaaa aggagctttc aatatggata aaccaactag acaaccaaag
     5941 tttcaggaac taacgccttc tcagttaact cagattactg gaggaggctg gcttgaaggt
     6001 cttcaaaaag ttttcaatgt ctctaagcca aaactactaa aatagtaaca ttctccattt
     6061 tcaaaacacc actacctaaa ggtactgaga cactatcgga atgatgtgat cctaaacatc
     6121 aaatctgata ggtgcaagac agttttcctt tactagtggt gtttttttat aacctaagct
     6181 caagtgtttg accaaataca tgattttgac ttatagtctt aatcatcaca ttgggataac
     6241 gattgataat ttccatagca ttataaagtc ccacacctct attatccccc ttggtgctta
     6301 ctccgaaatc atatagaaag gatagatcaa tcttctcttc cttagttgta ttttcaatca
     6361 taaatagttg cttattgtcc aaagtaaaat aagaaatcgt tatcttagac gaagaagctt
     6421 caacagcagc ctctatagca ttatcacata aaatagacac aatagtaaga aaatcaatca
     6481 gctccatgcc ttgcggactg atatcctctg gaacctctaa agatactgaa atcccacttt
     6541 ctaaagcctg actaaatttt gcagctaaaa gacttttcaa ggctgtgtca gtgacatgga
     6601 taagacgccc aacatcatat ttttgcttgc gaaatcgttt atttgaatcc ttaaagaccg
     6661 attgataaac tgacctaaca atagacatgc tatcattatc tataccaaac tttaacgtgg
     6721 caatcagatt gctatagtca tgacgaaatc ctcgaacctc tctgtaaagc tcctctatct
     6781 gacgactata gctctcaata tttgccagct gcagctctct ttgaaaggtc agtctttctt
     6841 gcagtgtatc tcttagcgac cggtccagtc tcgacacagt tcccataaat ataatccaat
     6901 agccaagcat catgcattga cgataggcat aagtatcaac agctagctca tactctaaat
     6961 aagcaagcaa ttggatcaaa aaataatagc taaccataga ccagttggtc acacctaaaa
     7021 ttcttttatc cctatcagat aaaagattaa ttcttaatgc tctgaaatca tatcgtagcc
     7081 accgcaaaaa gagaaaaacc atcaaagtag atactatatc tgtaaaaatt ccccaaaatc
     7141 catcatttgt taaatgataa tcaagtttaa aaagaggtaa gataaaaaaa ccaagcagtc
     7201 ggtaccaaag gctccacagg gtaataggaa atagcccata aaatatcaat aatgtttttg
     7261 ataagggtcg cagcaatagc catgatatca ctaccatata aattggaaga ctccaataat
     7321 tgagaagtga aatgtcggca acatgattag ctatagtgaa aaaaacagca aatcctattc
     7381 ttaaaaaagt actgaaagca acttcaagcc aggttaattg acgtccactg attttggaaa
     7441 agagcactaa cgataagcct atacttgtcg tcatttctaa gaaaaataaa ataagcttca
     7501 ttaattatct cctctatgta ggttctcaat tgttgttaaa acactgttca ttttactacg
     7561 agcaattaag cagctagagc catttcgaaa ataaaccact cgctcaatct tatctaccct
     7621 aacgacattc ctatgattaa tcaaaaaaga acgatgacat tgcaaaaaac gagactcttg
     7681 cttcaaaata tccgtcaaag tccccgtaaa ttgcattctc tccttttttg tatacaaatt
     7741 gacacgatgc gctcgtgacg atgtctcaat atacaggata tcattaaaag gcacctgtac
     7801 ctgagcataa cgagatgtaa aataaaaagc actttccgct atcgtttcac tattttgccg
     7861 cacagcatat aataaagcag tctctacccg ttgaacaaac tcagtttgag gcagctcttt
     7921 atcgatatag tccaaagcag atacctgata ctgaaaagcc aagggcataa attccgagtg
     7981 agtcgttaca aaaacaatca tcgcatctgg atttatctga cgaatttgcc tagcaacctc
     8041 aagccctttt ttgttctcat tttttatctc aatatctaaa aagaatagct gctgaccaca
     8101 gttcttcttg atagcactta atagctgatg aggccttcca aaacagtcaa gtccttgaaa
     8161 taatagctgg tgcttaacct caagctcttt aatgagcttt tctaaatatc tctgctgaat
     8221 catatcatct tctaaaataa ctactctcac ctaaactcag tcccctatcc aatctgcaga
     8281 agcattagca ctactaccgt ttcaacaaaa taataagcac aataacaaaa ataaatccat
     8341 taaaaacaac tgcatcaaaa ctcataaaaa taatattttg tacttatttt agcataaaat
     8401 accatttttg aatacactaa tctctaataa actaatgcta tctagtctta gctagcaata
     8461 acctagtgct tctaacaaca ataatcagct caacaatttt tagcagctac ctttttaaaa
     8521 aaactgggat aaaaagattt ctcaggtaag aaaaatagag attcaccaaa cagtgaatct
     8581 ctattttttg aactgaaact ccttttg
//
LOCUS       DARYYD010000073         8597 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.074, whole genome shotgun sequence.
ACCESSION   DARYYD010000073 DARYYD010000000
VERSION     DARYYD010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8597
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.074"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            26..217
                     /locus_tag="TV188_001753"
     CDS             26..217
                     /locus_tag="TV188_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535080.1"
                     /translation="MSLQLAEAVQEKPIQAVTVEDLTRHGIAESLKAYLQTMGLTNEE
                     AMKQYEEVLSDEIIQYFSS"
     gene            complement(339..1553)
                     /gene="thiI"
                     /locus_tag="TV188_001754"
     CDS             complement(339..1553)
                     /gene="thiI"
                     /locus_tag="TV188_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEL1535081.1"
                     /translation="MKYSEIMVRHGELSTKGKNRMRFINRLKANIQDVLSAYSEVTVR
                     STRDRTHVLLNGADDRSVIEALKPVFGIQGLSPVYKVEKSVPVLIAAVQEIMSSLYRE
                     GLTFKISSKRSDHQFELDSRDLNHTLGAAVFEALPHIKAQMKNPDVTLKVEIRDEAAY
                     LSHEDIKGAGGLPVGASGKGMLMLSGGIDSPVAGYLSLKRGVEIEAVHFASPPYTSPG
                     ALRKAKDLTQRLTRFGGNIQFIEVPFTEIQEEIKHKAPEAYLMTLTRRFMLRITDAIR
                     EKRKALVIINGESLGQVASQTLESMQAINAVTSTPIIRPVVAMDKLEIIDIAQQIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKLANVERYESRFDVDGLVERAVAGIRVTEITPEIE
                     TDSLSTLIEELL"
     gene            complement(1555..2697)
                     /locus_tag="TV188_001755"
     CDS             complement(1555..2697)
                     /locus_tag="TV188_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012766813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEL1535082.1"
                     /translation="MIYFDNAATTKPYEEALKTYQEVASKIYGNPSSLHQLGANASRI
                     LEASRRQIAALLDVEAKEIFFTSGGTESDNWAIKGIAFEKSHFGKHIIVSAIEHPAVR
                     ESAKWLESQGFELSYAPVTDKGVVDVKKLAALIRKDTILVSIMAVNNEIGSIQPIAAI
                     SELLADKPTITFHVDAVQAIGKLPVEAYLTARVDLASFSGHKFHAVRGVGFLYKKSGK
                     RITPLLVGGGQEDELRSTTENVAAIASMAKALRIITERQDRSQARIAAMKKVIYQALQ
                     AYEDTILFSEIDDFAPHILTFGIKGVRGEVIVHAFEKHEIYISTTSACSSKVGKSAGT
                     LVSMGIPAALAQTAVRISLDDDNDMGQVEQFLTIFKQIYEKTQKVR"
     gene            2937..3377
                     /locus_tag="TV188_001756"
     CDS             2937..3377
                     /locus_tag="TV188_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535083.1"
                     /translation="MSSHYSRQQKPKKSASIPTKHIKTGFTALQKTIALVGSVLSIVV
                     ATITINRALQPSNEQPKSDSSPSSTSTIVKIIEKESSHSNKEETDKTETNSDSSGTQA
                     THTTPSSADPATKDTEKQQNTETEAPAANQPTANEPAPNSTSNP"
     gene            complement(3447..4799)
                     /gene="gorA"
                     /locus_tag="TV188_001757"
     CDS             complement(3447..4799)
                     /gene="gorA"
                     /locus_tag="TV188_001757"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEL1535084.1"
                     /translation="MAIQYDYIVIGGGSAGIASANRAAMYGAKVLLAEGKAIGGTCVN
                     LGCVPKKVMWYGAQVAETIHTYAKDYGFTVLEDRFDFKTLKSNRQAYIDRIHASYEKG
                     FEHNGVDRIYDYARFIDQHTVDIAGKTYTAPHILIATGGQPIFPDIEGAELGISSDGF
                     FALDDIPKRTAVVGAGYIAVEIAGVLNALGSQTDLLVRYDRPLRTFDQDIIQVLVDEM
                     KVSGPRLHTNADVTKVTKANDGSLQVHLSDGRRLEVDQVIWAIGRKPNVTGFGLEHTG
                     VELDKKGYIAVDAYENTSVDGIYAVGDVNGKLALTPVAVAAGRRLAERLFHNKPNEKL
                     DYNKVATVVFSHPPIGSIGLTEEAAIQAYGQAAVRVYQSQFTSMYTAITSHRQPCLMK
                     LIVAGEEETIVGLHGIGYGVDEMIQGFAVAIKMGATKADFDNTVAIHPTGAEEFVTMR
                     "
     gene            complement(4993..5334)
                     /locus_tag="TV188_001758"
     CDS             complement(4993..5334)
                     /locus_tag="TV188_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEL1535085.1"
                     /translation="MSQDIYDYANKLERAVRALPEYRKALEAREEIKADEAASQLFDE
                     FVAVQEKLQGLMQTGQLPTETEQADIQALSQKIEANDLLKGYFNAQQALSVYVNDIER
                     IVFAPLKDLAK"
     gene            complement(5395..6561)
                     /gene="aroC"
                     /locus_tag="TV188_001759"
     CDS             complement(5395..6561)
                     /gene="aroC"
                     /locus_tag="TV188_001759"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014735687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEL1535086.1"
                     /translation="MRYLTAGESHGQALTAIIEGIPAGLALSAELINKELKRRQGGYG
                     RGARMRIESDRVHISSGVRHGKTTGAPITLTIQNKDHQKWLDIMAVEAVEEQIKFKRK
                     ITRPRPGHADLVGGIKYRFDDLRNALERSSARETAMRVAVGAIAKAILTELGIETANH
                     VLVFGGIEVAVPEAMSFADIKKVAESSDLSIVNPKQEATIKAHIDQVKKEGDTLGGII
                     ETLIHGLPAGLGSYVQWDRKLDAKIAQAVLSINAFKGVEFGMGFDMGYQKGSQVMDDI
                     IWHETSGYSRRTNRLGGFEAGMTTGQPIVVKGVMKPIPTLYKPLMSVDTETHEPYKAT
                     VERSDPTALPAAGVVMENVVATVITKEILEQFPSDNMTDLKQAFFAYRDYVHHF"
     gene            complement(6674..7354)
                     /locus_tag="TV188_001760"
     CDS             complement(6674..7354)
                     /locus_tag="TV188_001760"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEL1535087.1"
                     /translation="MKIVAPVMPRNVEEAQSIDVSKYQDVNLIEWRADFLPKEDIVSV
                     APAIFEKFAGREIIFTLRTSQEGGHITLSDQEYVDLIKEINAIYNPDYIDFEYFSHKA
                     VFHEMLDFPNLVLSYHNFDETPENLMEAFSEMTKLAPRVVKIAVMPQSEQDVLDLMNY
                     TRGFKTLNPEQEFATMSMGKLGRLSRLAGDVVGSSWTFVSLDQASAPGQVSLADMKRI
                     LHVLESED"
     gene            complement(7351..8514)
                     /locus_tag="TV188_001761"
     CDS             complement(7351..8514)
                     /locus_tag="TV188_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEL1535088.1"
                     /translation="MNKVCINPLVERKIAAGIQLLDEKDFDGTIWDYQLVQLVNSSHQ
                     LIGTAYLSKQHKGVGWYLGRSVKKLSVSYFVTLFKTAKKKREHFAASEWTNAYRLFNQ
                     DGDDFGGLTIDLYKDFALFSWYNVFVYQEKELIIQAFREVFPEVRGAYEKIRFKGPDK
                     ETAHLYGAFAPDTFTILENGVAYQVFLNDGLMTGIFLDQHEVRRGLVDGLALGKTVLN
                     LFSYTAAFSVAAAMGGAVETTSVDLAKRSRELSKAHFVQNQLDLSSHQLVVMDVFDYF
                     KYAKRKQLSFDLIIIDPPSFARNKKQTFSVSKDYHQLIAEALDLLAPKGTIIASTNAA
                     NMTVNQFKKQIIKGLGGRPLAQMTLEQLPSDFTINKADERSNYLKVFTIRVRE"
BASE COUNT         2517 a         2054 c         1604 g         2422 t
ORIGIN      
        1 tctcttatta actggctgtc actcattgtc tttgcagcta gctgaggctg ttcaggaaaa
       61 gcctattcaa gcggttacgg tagaggattt gaccagacat ggcattgccg aatccttgaa
      121 agcctaccta cagacgatgg gcttaaccaa tgaagaggct atgaaacaat acgaggaggt
      181 cctttctgat gagattatcc agtattttag cagctaaata agagaatttg agcaaaatca
      241 gctaaaaaca aaagccagag cctttaataa ctaataggtc tggctttttt tgactgttta
      301 gatagactgc ttatgttgta gggctaggtg cgcacctcct acaacaattc ctcaataagc
      361 gttgataagc tgtcagtttc gatttcagga gtgatctcag ttactctgat ccctgccact
      421 gctcgctcga ccaatccgtc gacatcaaag cgagactcat atcgttcaac atttgctagc
      481 ttgggattgg ttttgggacg atcaggagca aaaatagtac agcagtcttc aaagggctga
      541 atggaaatat caaaggtgtc aatttgctga gcgatatcaa tgatttctag cttatccatt
      601 gccacaactg gtctgataat cggagttgaa gtgactgcat taatagcctg catgctctct
      661 aaggtctggc ttgcaacctg tcctaagctt tcaccgttaa taatcactaa agcctttcgc
      721 ttctcacgaa tagcatctgt gatccgcagc atgaagcgtc tagtaagtgt catcaaatag
      781 gcttcgggtg ccttatgctt gatctcctct tgaatctcgg taaatggaac ctcgataaac
      841 tgtatattac ctccaaaacg tgttaagcgc tgcgttagat ccttggcttt tcttagcgca
      901 ccaggactgg tatagggtgg gcttgcaaaa tgcactgcct caatctcaac acctcgtttc
      961 agggatagat agcccgcaac cggtgaatca ataccacctg atagcatcag cattcccttt
     1021 cctgaagctc caaccggcag ccctccagct ccctttatat cttcgtgaga cagataagca
     1081 gcctcatcac gaatttcgac ctttagggta acatcaggat ttttcatctg tgccttgata
     1141 tgcggcaaag cctcaaagac ggctgctcct aaggtgtggt tgaggtcgcg gctatctagc
     1201 tcaaactgat ggtcactacg cttgctggat attttaaagg ttagcccttc gcgatacaag
     1261 gagctcataa tctcctgaac tgctgctatc agtacaggga cacttttttc aactttatag
     1321 acaggagata agccctgaat accaaacacc ggctttaagg cttcaatcac agacctatca
     1381 tctgcaccat taagtaaaac atgggtcctg tctcgagttg atctgactgt cacctcagaa
     1441 taggcagaaa gaacatcttg aatattagct tttagccgat taataaaccg catacggttt
     1501 tttcccttgg tcgataactc cccatgacga accattattt ctgaatattt catattatct
     1561 aaccttttgt gttttttcat aaatctgttt aaaaatcgtt aaaaattgct caacctgtcc
     1621 catatcatta tcatcatcta ggctgatacg gactgctgtt tgagccaatg ctgctggaat
     1681 tcccattgag actaaggttc ctgccgactt tccaaccttt gatgagcagg cactcgttgt
     1741 tgatatataa atctcatgct tttcaaatgc gtgcacaata acctctccac gaacgccctt
     1801 tataccaaag gtcagaatat gaggagcaaa atcatctatc tcagaaaaga gaatggtatc
     1861 ctcataggcc tgcaaggctt gataaataac ctttttcatg gctgctatcc ttgcttgaga
     1921 tctatcctgt ctttctgtga tgatccttaa agccttggcc atacttgcaa tagctgccac
     1981 gttttcagtt gtcgaacgta gctcatcttc ttgaccgcca ccgaccaata agggagtgat
     2041 tcgctttcct gattttttat aaagaaagcc aacaccacga acagcatgaa atttatgacc
     2101 agaaaaagaa gctaagtcaa cacgcgcggt taagtaagcc tcaacaggaa gcttcccaat
     2161 agcctgaaca gcatcgacat gaaaggtaat ggtgggctta tcagccaaaa gctctgatat
     2221 ggctgcaatc ggctgaattg acccaatctc attgttaacc gccataatgg aaactaatat
     2281 ggtatctttt cggattaagg cagctagctt tttgacatca acaactccct tatctgtgac
     2341 aggagcataa gacagctcaa agccttgact ttctagccat ttggcgcttt ctctgacagc
     2401 tgggtgctca atggctgaga caatgatgtg cttaccaaag tgagattttt caaaggcaat
     2461 ccccttgata gcccaattgt cgctttccgt tccgccagag gtaaagaaaa tctctttggc
     2521 ctctacatca agtaaggccg ctatttgcct gcgcgaagcc tccaatatac gactggcatt
     2581 ggctcctagc tgatggagac tagagggatt gccgtaaatc ttactggcca cttcctgata
     2641 cgttttaagt gcctcttcgt aaggcttggt agtggctgca ttatcaaaat aaatcatgtg
     2701 tcaccttcat ttttattcaa tactttattg tatcacaaat ttgatgaaat gaaaaaatag
     2761 atctttttgc aggataggac aactctatcc tagacaataa ggtaaaccgt tgacttgatt
     2821 tttgttctag attatactgg tagatgatag agctaagtct gaaatgcctg ttagccatta
     2881 aagacctaaa gcatttgact ttagctagcc tatgactcgt taaaggagat attctcatgt
     2941 catcacatta ttcacgtcaa caaaagccta aaaaatcagc aagtattccc acaaagcata
     3001 ttaaaactgg ctttaccgcc cttcaaaaaa ccattgcctt agttggtagt gttctgagta
     3061 ttgttgtagc gacaatcact attaatcgag ctctacaacc atcaaatgag caacccaaaa
     3121 gcgattcctc tccgtcatca acatcaacga ttgtgaaaat tattgaaaag gagtcgtcac
     3181 actcaaataa ggaagagact gacaagacag aaactaattc tgattctagc ggtactcagg
     3241 cgacacatac tactcctagc tcagctgatc ctgctactaa ggatacagaa aaacaacaga
     3301 ataccgaaac ggaagcaccg gctgctaatc aacccacagc taatgagcca gctcctaaca
     3361 gtacaagcaa tccataacac aaaacacgat aacaggcaat tcagataagc tctgaattgt
     3421 ctgctatcgt gttttatcat gtgctgttat ctcatggtaa caaactcttc agcacctgta
     3481 gggtgaatgg caacagtatt gtcaaaatca gccttagtag cccccatttt aatggcaaca
     3541 gcaaagcctt gaatcatctc atcaacacca taaccaatac catgcagacc aacgatggtc
     3601 tcttcttctc ctgcaacgat caatttcatt aggcagggct ggcgatgact agtaatagct
     3661 gtatacatgg acgtaaattg tgattgatag acacgaacag ccgcttgccc ataggcttga
     3721 atagctgcct cttctgttaa gccgatcgag ccaattggcg gatggctaaa gacaactgtc
     3781 gcaaccttgt tataatcaag cttttcattg ggcttattat gaaacaagcg ctctgccaag
     3841 cgacgacctg ctgcgacagc gactggggtc aaagcaagct ttccattaac atcaccaaca
     3901 gcatagatgc catcaacaga tgtgttttca taagcgtcaa cagcaatata gcccttctta
     3961 tccagctcaa ctcctgtatg ctccaagcca aagcctgtca catttggctt gcggccaatt
     4021 gcccaaatca cttggtccac ttcaagccta cgaccatcgg acaaatgcac ttgaagagag
     4081 ccatcattag ccttggtaac cttagtaaca tcggcattgg tatgcagcct tggtccagat
     4141 accttcatct catcgaccag aacctggata atatcctgat caaaggtcct cagtggcctg
     4201 tcatagcgaa ccagcaaatc cgtctgagaa cctagggcat tgagcactcc tgcaatctca
     4261 acagcaatat agccagcacc gacaactgct gttcgttttg gaatatcatc taaagcaaag
     4321 aaaccatctg agctaatccc cagctcagct ccttcaatgt caggaaaaat aggctgacca
     4381 ccagtagcga ttaaaatatg gggggctgta taggtcttac ctgcaatgtc aaccgtatgc
     4441 tgatcaataa atcgtgcata atcataaata cgatcaaccc cgttatgctc aaagcccttc
     4501 tcataagagg catgaatacg atcaatatag gcctgacgat tgctttttaa ggttttaaaa
     4561 tcaaacctat cctctaacac cgtaaacccg taatccttcg cataggtatg aatcgtttct
     4621 gctacctgtg cgccatacca catgaccttt ttaggcacgc agcccaaatt aacacaggtc
     4681 cctccaatag ccttgccctc agctaatagg accttagcac cgtacattgc tgcacgattc
     4741 gccgaggcaa tcccagcgct cccaccacca atcacaatat aatcatactg aattgccatt
     4801 aatttaccac ctttactctt aatgcttgcc tcaatagatt tgttattaag ctatcattat
     4861 tgctttattt taatctactg tcatttgact ataacataaa ataacttgtg tctcaaatcc
     4921 ctgctacgac aaaaaaagat tgtgataagc atcaacaatc ctttcttctc ttaatcctaa
     4981 gccagcttag ctctacttgg ccaaatcctt caatggtgca aatacaatcc gttcaatatc
     5041 attaacatag acggaaagag cctgctgagc gttaaaatac ccttttaata ggtcattggc
     5101 ctcaattttt tggctgagag cctgaatatc tgcctgctct gtctctgttg gcagctgacc
     5161 ggtctgcatg agtccttgca atttttcttg cacagcaaca aactcatcaa atagctgact
     5221 ggcagcctca tctgccttaa tctcttctct ggcttccaag gccttgcgat actctgggag
     5281 cgcacgaaca gctcgctcaa gcttattggc ataatcataa atatcttggg acatctggat
     5341 ctccttttat catttattat ccttatcata tcacaatatc aagccatttg tcgcttaaaa
     5401 atgatgaaca tagtcacgat aggcaaaaaa agcctgcttt aaatcggtca tattgtctga
     5461 tggaaattgt tccaaaatct cttttgtgat gacagttgct acaacatttt ccatcacgac
     5521 accggcagcc ggcagagccg taggatcaga acgctcaaca gtagccttgt aaggctcgtg
     5581 cgtctcagta tccacagaca ttaggggctt gtagagggtg ggaatcggct tcatcacccc
     5641 tttgacaaca ataggctgac cagtagtcat acctgcctca aagccaccta gtcggtttgt
     5701 tcgacgactg tagccgcttg tctcatgcca aatgatgtcg tccatgacct gcgagccttt
     5761 ttggtagccc atgtcaaagc ccataccaaa ttcgacccct ttaaaggcgt tgatagacag
     5821 gacagcctgc gcgattttgg cgtctaattt acgatcccac tgaacatatg aacctaagcc
     5881 tgctggtaag ccatgaatga gtgtttcaat aataccacca agcgtatctc cttctttttt
     5941 gacttgatca atatgggcct tgatagtcgc ctcttgcttg ggattgacaa tagataaatc
     6001 agaagactct gctacttttt tgatatctgc aaaggacatc gcctcaggca cagctacctc
     6061 gataccacca aaaactagga catgattagc agtttcgatc ccaagctcag taaggattgc
     6121 cttagcaatt gcaccaacgg ccacacgcat cgctgtttct ctggcagagg agcgctcaag
     6181 cgcatttctt aaatcatcaa aacgatattt gatcccccca accaagtcag catgaccagg
     6241 gcgtggacga gtgattttac gcttgaactt gatttgctct tcaacagcct caacagccat
     6301 aatgtctagc catttttgat ggtccttgtt ttgaatggtt aaagtaattg gtgctcctgt
     6361 tgttttgcca tgacgaacac ctgaagagat atgcacacga tctgattcaa tgcgcatgcg
     6421 tgcgccacga ccatatcccc cctgccgacg cttcagttcc ttgttaataa gctcagctga
     6481 taatgctaag cctgcaggaa ttccctctat aatggccgtc aaagcttgtc catgtgactc
     6541 acctgctgtt aaatacctca ttattcctcc atttatcaat catagacata aaaagcaaac
     6601 ctgccctcct ctagacaact aaaagacatt attctaagct atccaagaga ataatgtctg
     6661 ttaccgtatc ttatcaatcc tcagattcca aaacatgaag aatccttttc atatcagcca
     6721 aggaaacctg ccctggtgca ctggcttgat ctaaggacac aaaagtccac gaggacccta
     6781 caacatcacc tgccaagcgt gatagtctgc ctagctttcc cattgacatg gttgcaaatt
     6841 cctgctctgg gttaagtgtt ttaaagcctc tggtataatt catcaaatcc aaaacgtcct
     6901 gctcgctctg tggcatgaca gcaatcttga caacgcgagg agctagctta gtcatctccg
     6961 aaaaagcctc catcagattt tcaggcgtct catcaaaatt gtgataagac aagacaagat
     7021 tcggaaagtc aagcatttca tgaaagacag ccttgtgact aaagtattca aagtcaatat
     7081 agtcaggatt ataaatcgca ttgatctcct tgatcaaatc aacgtattcc tgatcagaaa
     7141 gtgtaatatg ccctccttct tgacttgtac gaagggtaaa aataatctct ctacctgcaa
     7201 atttttcaaa aatagctggc gctacagaaa caatatcctc cttaggaaga aagtctgctc
     7261 gccactcgat taaattaaca tcttgatatt tagaaacgtc gatagattga gcctcttcaa
     7321 catttcttgg catgactggt gctacaattt tcattctcgt acccttatag taaatacctt
     7381 taaataatta cttctttcat ctgctttatt gatagtaaaa tcacttggaa gctgctcaag
     7441 tgtcatctga gctaatggcc tgcctcccaa tcctttgata atttgctttt taaactggtt
     7501 aacagtcata ttggcagcat ttgttgaagc gataattgtt cccttggggg ccaataggtc
     7561 tagagcctca gcgattaatt gatggtaatc cttactcact gaaaacgtct gctttttgtt
     7621 tctggcaaag cttggtggat caataataat aagatcaaaa gaaagttgct ttcgcttagc
     7681 atacttaaaa tagtcaaaaa cgtccataac cacaagctga tgactggata ggtccaactg
     7741 attttgaaca aaatgagcct ttgataactc tctggagcgc tttgccaaat caacagaggt
     7801 tgtctcaact gcaccgccca ttgctgcagc tacagaaaaa gctgctgtat atgagaacag
     7861 gtttaaaaca gtctttccaa gcgccaagcc gtccaccaga cctcgtctaa cctcatgctg
     7921 atcaagaaaa atccctgtca tcaagccatc atttaaaaat acctgatagg ctacgccatt
     7981 ttctaaaatg gtaaaggtat caggagcaaa cgcgccatac aaatgagccg tctccttatc
     8041 tggtccctta aagcgaatct tttcataagc tcccctgacc tcaggaaaaa cctctcgaaa
     8101 agcctgaata ataagctcct tttcttgata aacaaagaca ttataccaag aaaataaagc
     8161 aaagtcctta tagaggtcta tggttagtcc tccaaaatca tcaccgtctt ggttaaaaag
     8221 acggtaagca tttgtccatt cagacgcggc aaaatgctct cttttcttct tagctgtctt
     8281 aaataaggtc acaaaataag aaaccgacaa tttcttaaca gaccttccta gataccagcc
     8341 tactccctta tgttgctttg aaaggtaagc tgtgccgatg agctgatgag atgaattcac
     8401 aagctgcact aactggtagt cccaaatggt gccatcaaaa tccttttcat ctagtaattg
     8461 tatccctgct gctatcttgc gttcaacaag gggattaata cagaccttat tcatagtttc
     8521 tattataaca aaaactatta aaaaatcata ctagatttaa acttattgca agcattagct
     8581 ccatattttt ggtataa
//
LOCUS       DARYYD010000074         8115 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.075, whole genome shotgun sequence.
ACCESSION   DARYYD010000074 DARYYD010000000
VERSION     DARYYD010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8115
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.075"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(2..2005)
                     /locus_tag="TV188_001762"
     CDS             complement(2..2005)
                     /locus_tag="TV188_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HEL1535089.1"
                     /translation="MSNAHHDAFDKATKAGFIIALGIVYGDIGTSPLYTMQSLVDNQG
                     GLSQVSEAFILGSVSLIIWTLTLVTTIKYVLIALKADNHHEGGIFSLFTLVRRMSRWL
                     IIPAMLGGATLLSDGALTPAVTVTSAIEGLKAVPELSSIYQNQTNVILTTLLILMVLF
                     GLQRFGTGVIGKLFGPVMLVWFSVLGISGLLNSLQHLEILKAINPYYALHLLVSPENH
                     RGIFILGSIFLATTGAEALYSDLGHVGRGNIYASWPFVKVCIILSYCGQAAWILAHKD
                     SGIALNPFFASVPEGLRVYLVILATLAAIIASQALISGSFTLVSEAMRLKIFPLFKIT
                     YPGANLGQLYIPVINWSLFAVTSCTVLYFRTSAHMEAAYGLAITITMLMTTILLAYYL
                     IKEGVKPLLASLLMAFFAFIEFIFFLASAVKFMHGGYVVVVLALAIVFVMVIWHAGTM
                     IVAKYVKSLSLNDYKHQIKLLRDDLRFDLYQTNVVYLTNRMKKDLIDRSILYSILDKR
                     PKRAQVYWFVNVRVTDEPYTATYKVDMLETDYIVCVELYLGFRMPQTVPRYLRTIVQD
                     LMESGRLPKQAQDYTITPGREVGDFRFVIIEERVSHARQLSTLERFVMQTKASIKHVT
                     ASPMRWFGLQYSEATVEVVPLLLSDVLKLPIKEIKACTKDEKA"
     gene            complement(2132..3748)
                     /locus_tag="TV188_001763"
     CDS             complement(2132..3748)
                     /locus_tag="TV188_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEL1535090.1"
                     /translation="MKFTAFNLSEDIQSAVVTAGFEKASPIQELTIPLALEGRDVIGQ
                     AQTGTGKTAAFGLPTLNKIRTADNTIQALVIAPTRELAVQSQEELFRFGRDKGVKVRS
                     VYGGSSIEKQIKALKSGAHVVVGTPGRLLDLIKRKALRLDHVETLILDEADECLNMGF
                     LEDIEAIISRVPDDRQTLLFSATMPAPIKEIGVKFMKDPEHVQVKNKELTNVNVDQYY
                     VRVKEQEKFDTMTRLMDVQQPELSIVFGRTKRRVDEITRGLKLRGFRAEGIHGDLDQN
                     KRLRVIRDFKNDQLDILVATDVAARGLDISGVTHVYNYDITQDPESYVHRIGRTGRAG
                     KSGESITFVSPNEMGYLTMIEHLTKKRMKPLKPATAEEAFQAKKKVALKKIERDFADD
                     AIRSNFEKFKGDAMKLAAEFTPEELALYILSLTVQDPDTLPEVEIAREKPLPFKYVGG
                     GHGNKNGKTGRGNRSRSGRDNRRGGYRHEKRNVYDGDRRPRRDKRDSHDSSGSYDFKR
                     KQKRSNKDLHKKGKAVEAKTSGFIIRHKGN"
     gene            complement(4164..5708)
                     /locus_tag="TV188_001764"
     CDS             complement(4164..5708)
                     /locus_tag="TV188_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEL1535091.1"
                     /translation="MSITEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKSGQFAKSDWMDFEKQRGISVTSSVMQFDYAGKRINILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRNIPVFTFINKLDRDGREPLELLEELEEVLG
                     IASYPMNWPIGMGRAFEGLYDLHNKRLELYKGEQRFADLEEGARIFASNPFYEQVLED
                     IELLEEAGNDFSEQAILDGQLTPVFFGSALTNFGVQTFLDTFLAFAPEPHGHKTTTDQ
                     MIDPLNQDFSGFVFKIQANMDPKHRDRIAFVRIVSGEFQKGMAVKLSRTGKSVKLSNV
                     TQFMAESRENVQNAVAGDIIGVYDTGTYQVGDTLSVSKNLFEFEPLPTFTPEIFMKVA
                     PKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VIMTPMGKKTVRWISEEDLDQRMSSSRNILARDRFDQPVFLFENDFALRWFADKYPDV
                     KLEAKM"
     gene            complement(5877..6572)
                     /locus_tag="TV188_001765"
     CDS             complement(5877..6572)
                     /locus_tag="TV188_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEL1535092.1"
                     /translation="MNFFAIEPIGLPHVSLLFYLLSVMIAPFLVFMTLQLYQLKSYRY
                     IFLGLQLVQLVGLYSWYALRGFPLTEALPLYHCRMAMLAIFFLPDRSSLKQLFMVLGI
                     GGTFLALLSPDLYPYQLWHVANISFYLGHYALLVNGLVYLLRFYNPSQLKPVLVCRYL
                     ATINFVLVLINLATKGNYGFVMDIPIIHTHHLLMNFVIVTMGLTGLIKLIELIYVRFS
                     EANQLELKLSKER"
     gene            complement(6656..8041)
                     /locus_tag="TV188_001766"
     CDS             complement(6656..8041)
                     /locus_tag="TV188_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEL1535093.1"
                     /translation="MKLTLHEVARVVDAQNSLSDLDDVPLNQIEFDSRNITKGDLFLP
                     LQGERDGHDFIDLAFENGAVATFSERAISGRPYILVENCLAAFQKLAQYYIDKLRVDV
                     IAVTGSNGKTSTKDMIEAVLAKAYKTYKTQGNYNNDIGLPYTVLHMPEDTEKIVLEMG
                     QDHMGDIQLLSRIARPHIALLTLIGEAHLAYFGSREKIAEGKMQIVDGMDSNGILIAP
                     GDPILDPYLPDSQMVIRFGDHQELVVEDIKECKDSLTFRTNVLPRPVTLPLTGKYNAT
                     NAMIAAYVGKLLAVPDEDIIEALETVKLTRHRTEWVKAANGADLLADVYNANPTAMRL
                     ILETFAAIPANPNGKKIAVLADMKELGADSVALHSQLITSLDPKRIDQLVFYGDDIQA
                     LAKLASQDYPSGRVSFFKKNNREDQYEDMCQYLLTILEPNDQMLLKGSHSMLLANVVD
                     RLTAPHAGKSS"
BASE COUNT         2468 a         1932 c         1519 g         2196 t
ORIGIN      
        1 cctaggcctt ttcatctttt gtacacgctt tgatttcctt gattggaagc tttaagacat
       61 ctgataagag taaaggaaca acctcaactg ttgcctcaga atattgcagg ccaaaccaac
      121 gcatagggct tgctgtcaca tgcttgatac tagcctttgt ctgcatgaca aaacgttcca
      181 gagtactcag ctgccttgca tgcgacacgc gctcctcaat gatcacaaac ctaaagtcac
      241 caacctctcg acctggtgta atcgtgtaat cctgagcttg cttaggcaga cgaccactct
      301 ccatcaaatc ctgaacaatc gttctaaggt aacgtggaac agtctgtggc attctaaagc
      361 caaggtagag ctctacacaa acgatatagt ctgtttctaa catatccacc ttgtaggtcg
      421 ccgtataagg ctcatctgtc acacgaacat taacaaacca ataaacctgt gcgcgcttag
      481 gacgcttatc taaaatagaa tacaggattg agcgatcaat cagatctttt ttcatgcgat
      541 tggtcaagta aacaacattg gtctgataca aatcaaagcg aagatcatct ctgaggagct
      601 tgatttgatg cttgtaatca tttaggctca aggacttaac atatttagca acaatcatgg
      661 ttccagcatg ccaaatcacc ataacaaaga caatggcaag agctaaaaca acaacaacat
      721 agcccccatg cataaactta actgcagacg ctaaaaagaa aataaactca ataaaggcaa
      781 aaaaagccat gagcagacta gccaggagcg gctttacccc ctccttaata aggtaatagg
      841 ctaagagaat cgttgtcatc agcatggtaa tcgtgatggc aaggccatag gcagcctcca
      901 tatgcgctga tgttctaaaa tacagcaccg tacaagacgt taccgcaaac aagctccagt
      961 taatgacagg gatgtatagt tggcctaggt tggcacctgg ataggtaatc ttaaacaacg
     1021 gaaaaatctt caagcgcata gcctcagaaa ccaaggtaaa ggaacctgag attaaagcct
     1081 gcgaagcaat aatggctgct agagttgcta gaataacaag ataaacccgt aatccctctg
     1141 gaacactagc aaagaaggga ttaagcgcaa tgcctgagtc cttatgcgct aaaatccaag
     1201 ctgcctgacc acaataggat aagatgatac aaaccttaac aaagggccag ctagcataaa
     1261 tatttcctcg accgacatga cctaaatcag aataaagagc ttcagcacca gttgtcgcta
     1321 aaaaaataga gcctaaaatg aaaatacccc gatgattttc cggactaacc aataagtgca
     1381 gcgcataata gggattgata gcctttagga tttccaaatg ctgtaagcta ttcaagagac
     1441 cactgatccc caaaacgcta aaccaaacca gcatgactgg cccaaataat ttaccaataa
     1501 cacccgttcc aaagcgctgc aggccaaaca agaccatcaa tatcagcaag gtcgttagga
     1561 tcacattggt ctgattctgg taaatactgc tgagctcagg aacagccttt aagccttcaa
     1621 tggctgatgt gaccgtaaca gctggtgtca aggcaccatc tgataagagc gttgctcccc
     1681 caagcatagc tggaatgatt aaccaccttg acatccttct aactaaggta aagagtgaaa
     1741 aaatccctcc ctcatgatga ttatcagcct ttaaagcaat caaaacatac ttgattgtcg
     1801 ttaccaaggt tagagtccaa ataatcaagg atactgagcc taaaataaaa gcttcagaca
     1861 cctgtgaaag gccgccttga ttgtcaacca acgactgcat ggtatacagt ggacttgtgc
     1921 caatatcacc atagacaatt cctagtgcaa taataaaacc tgcctttgtt gctttatcaa
     1981 aggcatcatg atgggcatta gacatcccaa tgttcctcct aagacttaat catgccaaat
     2041 ggactgagac cattatagca aaatctataa caaaatcaat attttcagaa aattaaaaag
     2101 agagctgaca atcatcagct ctcttgaaac tttagttccc tttatgacgg ataataaatc
     2161 cagacgtctt agcttcgaca gccttgccct tcttgtgcag gtccttgtta gagcgttttt
     2221 gctttcgctt aaagtcatag ctaccactgc tatcatgact gtcacgttta tcacgccttg
     2281 gacggcggtc accatcataa acatttcttt tctcatgacg atagccacct cgacggttat
     2341 cacgaccgct acgactacga ttgccacgac ctgtcttgcc atttttattg ccatgaccac
     2401 caccaacata cttaaacggt aatggctttt cacgcgctat ctcaacctct ggtaaggtat
     2461 ctggatcttg gacggtcaag ctaaggatat agagcgctag ctcctctggg gtaaactctg
     2521 ctgccaattt catcgcatcg cccttaaatt tctcaaagtt tgagcgaata gcatcatctg
     2581 caaaatcacg ctcaattttt ttgagggcaa cctttttctt agcctgaaag gcttcctctg
     2641 ccgtagctgg cttgagtggc ttcatgcgct tcttagtcag gtgctcaatc atggtcagat
     2701 agcccatctc atttggtgag acaaaggtaa tggattcccc tgacttacct gcacgaccgg
     2761 tccggccaat acggtgcaca tagctttctg gatcctgtgt aatatcgtaa ttgtacacat
     2821 gagtaacgcc tgaaatatca agcccacgcg cagcaacatc ggttgccact aaaatatcaa
     2881 gttgatcatt tttaaagtcg cgtatgacac gaaggcgctt attttggtca aggtcaccat
     2941 gtatcccttc tgcgcgaaaa ccacgcaatt ttaagccgcg cgtgatttca tcaacacgac
     3001 gctttgtgcg accaaataca attgatagct ctggctgctg aacgtccatc agacgtgtca
     3061 tggtatcaaa tttttcttgc tccttaacac gcacatagta ttgatcaaca ttcacatttg
     3121 ttaattcctt gtttttaacc tgaacatgct caggatcctt cataaacttg acaccaattt
     3181 ccttgattgg agctggcatt gttgctgaaa ataacagggt ttgacgatcg tcagggacac
     3241 gactaataat cgcttcaatg tcctctaaaa atcccatatt caagcattca tcagcttcat
     3301 ctaaaatgag tgtctcaaca tggtctagcc tcaaggcctt acgcttaatc aaatctaaca
     3361 gacgtcctgg cgttccaaca acgacatgcg ccccagactt tagggcctta atttgcttct
     3421 caatgcttga gccaccatat actgagcgaa ccttgacgcc tttatcacga ccaaaacgga
     3481 acagctcttc ctgactttgg acagccagct cacgcgtcgg agcaatcacc aatgcctgaa
     3541 tggtgttatc ggctgtacga atcttattca gagttggtag accaaaggct gctgtttttc
     3601 ctgttcctgt ctgagcctgt ccgataacat ctcgtccctc caaggctaac ggaatggtca
     3661 gctcctgaat aggagaggct ttttcaaagc ctgctgtaac aacagctgac tgaatatctt
     3721 ctgataagtt aaatgctgta aatttcaatt gtttctcttt tctaaaaagg cagtgcgaag
     3781 ctgccttata aaccttttaa tattgtcgtt cgattaacaa cctatttagt gtaacataat
     3841 taatattaaa aagataggaa ataagccatg aaagtgtttt tatctcaaaa tgattaacac
     3901 tatcaggcag ctaaattgat aaaagcgtca ctccttattg ctgattggct aacagcctca
     3961 aaaaggcctc gtcggacttg cttacctatg ctttttatct actctgctaa aaagactcgg
     4021 cacagagacg agccttcgcg attccatcac caatcttcaa agacagcaat taggattcct
     4081 gaaagctcct tatgccaata gcctgccttt tcttagcagc agaagtgcaa aaacggacta
     4141 ggttccccta atccgcttag ctgctacatt tttgcttcta gcttaacatc tgggtattta
     4201 tctgcaaacc aacgaagcgc aaagtcattt tcaaagagaa aaacaggctg atcaaagcga
     4261 tcccttgcca aaatgtttcg gcttgaggac atgcgttggt ccaaatcctc ctctgagatc
     4321 caacgaacag tctttttgcc cattggtgtc atgatgacct ctgcattgta ctcaccctcc
     4381 atacggtgct tgaaaacctc aaactgcagc tgaccaactg cgcccagcat gtattcacct
     4441 gtctgataat tcttataaag ctgaacagcc ccctcctgta caagctgctc aatacctttg
     4501 tggaaagatt tttgcttcat gacattctta ggtgcaacct tcataaaaat ctctggggta
     4561 aaggtcggca atggctcaaa ttcaaacagg tttttactaa cgctcaaggt atctccaacc
     4621 tgataagtcc ctgtatcgta gaccccaata atatcaccgg caactgcatt ttggacattt
     4681 tcacgagact cagccataaa ctgagtaaca tttgatagct taacgctttt acctgtacga
     4741 gacagcttta cagccattcc cttttgaaac tctccagaga caatacgcac aaaggcaatg
     4801 cggtcacgat gcttagggtc catgttagcc tgaatcttaa agacaaagcc tgaaaaatcc
     4861 tgattgaggg gatcaatcat ctggtccgtt gtcgtcttat gcccatgagg ctctggtgca
     4921 aaggctaaaa aggtatctaa aaaggtttgt accccaaaat ttgttaaggc agagccaaag
     4981 aataccggag tcagctgacc atctaaaata gcctgctctg aaaagtcatt acctgcctcc
     5041 tccaagagct caatatcttc aagcacctgc tcataaaaag ggttgctggc aaaaatcctt
     5101 gccccctcct ctaaatcagc aaacctctgc tcccccttat aaagctccaa gcgtttgttg
     5161 tgcaaatcat acagaccttc aaaggctcgt cccataccaa ttggccagtt catggggtaa
     5221 gaagcaatcc caagaacctc ttctagctcc tccaacaact ccaaaggctc acgtccatca
     5281 cgatctaatt tattaataaa cgtaaaaaca ggtatgttac gatgcttaac aacctcaaag
     5341 agctttttcg tctgtgcttc gatcccttta gccgaatcaa caaccatcac agcagcatca
     5401 actgccatta aggtacgata agtatcctct gaaaagtcct cgtgaccagg tgtatctaaa
     5461 atattgatac gcttaccagc ataatcaaac tgcatgactg atgatgtgac tgaaatccca
     5521 cgttgctttt caaaatccat ccaatctgac ttagcaaatt gaccagattt ttttccttta
     5581 acggtcccag cctcacgaat ctcaccacca aaataaagta actgttctgt aatagttgtt
     5641 ttaccagcat ctgggtgact gataatcgca aaggttcgac gctttttaat ttcttctgta
     5701 attgacattc ttttttcctt atttgttcac attgcagagc aagactctga ttaatagctt
     5761 caagtcacac gtcacagtta tgtctacatg atctcactcc taaatactga tatgataaaa
     5821 agagctgcta gagcagctcc tttattatag ctgattcgaa gcgctttttc aacgccctat
     5881 ctttctttag agagcttcag ctctaactga ttggcctcac taaatctcac atagataagt
     5941 tcaatcagct taattaaacc agtcaacccc attgtcacaa tgacaaaatt cataagcagg
     6001 tgatgcgtat gaataatcgg aatatccatc acaaagccgt aatttccctt tgttgccaaa
     6061 ttgatcaata ctaaaacaaa attaatggtt gccaagtaac ggcaaacaag gactggcttt
     6121 agctgacttg gattgtaaaa ccgcagcagg taaaccaagc cattgaccaa aagagcataa
     6181 tgccccaggt aaaaagaaat attagccaca tgccatagct gataagggta taaatcaggt
     6241 gataacaggg ccaaaaaggt cccaccaatc cctaaaacca taaaaagctg ctttaagcta
     6301 ctgcgatccg gtaagaaaaa gatagctagc atggccattc ggcaatggta aagcggcaaa
     6361 gcctctgtca acggaaagcc tcgcaaggca taccagctat acaaaccaac caattggacc
     6421 aactgaagcc ctaagaagat atagcgatac gactttagct gatagagctg cagggtcata
     6481 aaaaccaaaa acggcgctat catcaccgac aatagataaa atagcaagga cacatgcggt
     6541 agcccaatag gttcaattgc aaaaaaattc ataaacatcc ctttctacat tttttcatta
     6601 taccttaatc ttaatgagag gacaagatgt ttcatgtgtt ttttctgaaa aagtgttagg
     6661 aggacttccc agcatgagga gctgtcaggc gatcaaccac atttgctagc agcatggagt
     6721 ggctgccctt tagcagcatc tggtcattag gctcaagaat agtcaacagg tactggcaca
     6781 tgtcctcgta ttgatcctct cgattattct ttttaaagaa gctaactctg ccacttggat
     6841 aatcttgact agctagcttg gccaaggctt gaatatcatc accgtaaaag accaattgat
     6901 caatacgctt gggatctaag ctggtaatca gctgagaatg caaagcaact gagtcagcac
     6961 ctaattcctt catatcagct aaaacagcta tttttttgcc attagggttg gccggaatgg
     7021 cagcaaaggt ttccaaaatt aaccgcatag cagttggatt ggcattgtac acatctgcca
     7081 aaaggtcggc gccattagcc gccttgaccc actcggttcg gtggcgtgtc agcttgacgg
     7141 tttctaaagc ttctataata tcctcatcag gcacagccaa gagtttacca acataagctg
     7201 ctatcatagc attggttgca ttgtattttc cagttaaggg aagagtgacc ggtcttggta
     7261 agacattagt cctaaaggtc aaggagtcct tgcactcttt gatatcctca accaccagct
     7321 cttgatgatc gccaaagcga atgaccatct gactatccgg caaatatgga tcaaggatag
     7381 gatcaccagg agcaattaaa atcccgttag agtccatccc atcaacgatt tgcattttcc
     7441 cttcggcaat cttctcgcga gagccaaagt aggctaagtg agcctcacca ataagggtta
     7501 gcaatgcaat atgaggtctg gcaattctag agagcagctg aatgtctccc atatgatcct
     7561 gccccatctc taaaacaatc ttctcagtat cctctggcat gtgaagcacc gtataaggca
     7621 agccaatgtc attattataa ttgccctggg ttttgtaggt cttataagct tttgccagga
     7681 ccgcttcaat catatccttg gttgatgttt taccgtttga gcctgttaca gcaatgacat
     7741 cgacacgtag cttatcaata taatactggg ctaatttttg aaaggcagcc aagcaattct
     7801 caactagtat atagggtctg ccactgattg ctctttctga aaaggtagct acggccccat
     7861 tttcaaaggc taagtcaata aaatcatggc catctcgctc accctgtagc ggtaaaaaaa
     7921 gatcaccttt tgtgatgttt ctactgtcaa attcaatctg attcagagga acgtcgtcta
     7981 aatcagaaag actattttga gcatcaacaa ctcttgccac ttcatgtaat gttaatttca
     8041 tcttattttt cctcttaaaa cactggtttt taaagctttg cttatattat agcataacat
     8101 attaggaata ttctt
//
LOCUS       DARYYD010000075         7813 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.076, whole genome shotgun sequence.
ACCESSION   DARYYD010000075 DARYYD010000000
VERSION     DARYYD010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7813
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.076"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            8..2059
                     /locus_tag="TV188_001767"
     CDS             8..2059
                     /locus_tag="TV188_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003034190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1535094.1"
                     /translation="MIDIKENIDDFNEIRNEYRQMLLNQSSKGNNGLSKSMYITFTIE
                     AEDLKQAKSRLERMEMDVLNNFKQMGVKAYVLDGEERLKTIHDILNPNDKLVFSFEDL
                     KYSGLTTKEYIVPPSFNFSKPTYFKTGEVFAEVNFLQLLASDIKDEMLSEFLALEENM
                     IVTFHIRAIDQMEAIKHVKRKITDLDKMKLEENKKAIRAGYDMDILPSDLVTYGAEAK
                     NLLSELQNHDEKMFLITILFMNTSKSKGKLDNTVFTLKSIANRHNCSLKNLNYRQEQG
                     LVASLPLGINEVEIERGLTTSAAAIFIPFTTEELFIKGESLYYGLNALSRNIIMADRK
                     KLKNPNGLILGTPGSGKSFAAKREITNAFLITDDDIIIADPEAEYSPLVEALKGQVIR
                     ISPISKDYVNPLDINIDYADEDNPLSLKSDFILSLFELVVGEKKLSAEEISVIDRCLP
                     ILYKTYFENPVPENMPILEDLYNLLQKQEEIVGKKLAVEMEIYVKGSLNVFNHRTNVD
                     TNNRVVCYDIKELGKQLKKIGMLVVQDQVWNRVTINRASKKATRYYVDEFHLLLKEPQ
                     TANYSIEIWKRFRKWGGMPTGLTQNIKDLLASPEIENIFDNTDFILMLNQAGTDRDIL
                     AKKLNISKHQLSYVTNSGEGEGLIFYGNTIVPFIDQFPKNTKLYSLITTKPEEVKKAG
                     E"
     gene            2061..3086
                     /locus_tag="TV188_001768"
     CDS             2061..3086
                     /locus_tag="TV188_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEL1535095.1"
                     /translation="MSVSRSKEEFIKENTNKIICSDALETLRKIPDESISCCITSPPY
                     YRLRNYHKEGQIGRESTVEEYLDRLLQVFREVRRALKKEGTCFIVIGDSYADSGGGKG
                     QYIDPKYPKARNGSNALATENISGYKSKDLMGIPWRLALLLREDGWYLRSDIIWHKEN
                     AMPEACRDRPTRSYEHIFLLTKSPKYYYDYDAMVEPMKEVSKKRYVRGRKSDNKYLKE
                     NSGAKLQKINEARKYGEYKGDNVPQFRNKRDIWTINTTSFRGNHYATFPPKLVEICMI
                     AGCPKNEIVLDPFIGSGTVGFVALRHNRKYIGIELNEEYVNLAKNRISEEVKKFNEEQ
                     KQEVQKE"
     gene            3052..5340
                     /locus_tag="TV188_001769"
     CDS             3052..5340
                     /locus_tag="TV188_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1535096.1"
                     /translation="MKNKNKRYKKNREKLLNQEIQSLQSQTQDNYETGSSKNQNETLL
                     KDETYDKKQFLSEKKLSNHLDNRHINNYSDRTISSYCLSDTGNINQNRSSFQAEKHKK
                     KMQKQINKFQKGEKEVYDPLSKDMDNDGVIDRYDVDFRDSKVSYRTLTDDEKYDNNQN
                     DKGKNYNDYVKNPKSKNKRYKNYVKDTFSKERMKSENQKKYVRSNFDDEEFTRNKDTK
                     NNLFQDVNNKRKTTDKNSSRKRKGKFENKEKKISKLQQKKQRQEQKLKNKGIDGKSQS
                     AKSAVIATGMAKRYLESGKEDNAGVGTAYKVTDQVENISRKIYYHGKKKNLKRQKKIT
                     KLGKSIDKQEKKLFFQKNMEEMKKSVDYQNTSRLRQFFKRRQYKNQIQKKYKDSVKNR
                     IKKSFIEGSKRFGEFVKGRGKKIIFLSLLAVGIFFMLFQAGSMMMNMGTGMVSNTVST
                     TYLSSEDTLKEINQRFSSLEQALQEEMDSVEENHPGYDEYIIKGKEKIGHNVHELLSY
                     ITARYGIVKNISEVESELKHLFQKMYTLTYKEEIEIRYRTVTSSYTDADGNEHTESHE
                     EPYEYRKLIVTLEKREMDGIIREAFKRYPNNLAHYETLFLTQGNMGEVFGNIDLINSN
                     GGIGGGKEYEASSEVQKKIVNAAYITPSPGAGWCAMWVSQVYQNAGLGFIGGNACDMY
                     RNYTFTSDRSKLKVGMLVAVESSSSGSSLGVTYGHVGIYIGDGKVMDNIGHIRVTTLD
                     DWIATFCKHHPVGFGFPPSVQK"
     gene            5353..5640
                     /locus_tag="TV188_001770"
     CDS             5353..5640
                     /locus_tag="TV188_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009530021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1535097.1"
                     /translation="MNKKYRKNIEKQKDIQKKIEELQLKQEMLKEEQEEMENIEVLKE
                     YRSIDISIDDFLEMMRRYKKEEKQEKMKLQEMRNTENHNNMEENHENQMEE"
     gene            5645..7081
                     /locus_tag="TV188_001771"
     CDS             5645..7081
                     /locus_tag="TV188_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014612398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HEL1535098.1"
                     /translation="MAITLSGVIFLILALLGTMLFNHQIVFAQGSLIPTLISPTEVLA
                     QTKVEVKIKYIFKDESVYKEEIIEVETGQVLDSGDLPMLEDNMKFIDEFLFYKVKGDG
                     TDEIIRKVEKITVKDKEIQTEEEKPKQDESTETEDKKTEDKGTQTELSKDDISKMEKE
                     AKELQDKLDKLNGEIRDKDKLSDKQKEKIKDLEAEIESLKEKMKKDKGNKDLSEDMKK
                     EIDKLTEKVKELEKKPTETNKAPVTSQSVTPISPISGIKTSSGISSQTPQSSGKGSSD
                     AVSSGNTTKDTGKTESKEKEKEVRYPNKLTPKAPANNSSQDSSMDGASSNVNTNKGVA
                     SAPSKARGTVTENKDNANNDYPIHHGDSSDNKEADKYSADARQFITFQTKSGKTFHLI
                     INHDEQSENVMLLTEVSEDDLLNMVEKKENPQEEIKKMEETVPESEVKKEEPKKEEGK
                     GSGSYIFLGIIVLAVVGAGYYFKIYKKK"
     gene            7334..>7813
                     /locus_tag="TV188_001772"
     CDS             7334..>7813
                     /locus_tag="TV188_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005956659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HEL1535099.1"
                     /translation="MNYENKIEKYLKQSGGIITTAYCKENNIPTIYLSRLLKDGRLSK
                     VRKGIYITKDGDYDEYYFFQHQYKKAIFSYETALYLLGQTDKIPWSIDVTVYNGYKFN
                     EKPNGFNVHYVKKSIYDLGVTQKPTMFGNKVKVYSYERTLCDFIAHKEEMDIEVYVKL
                     "
BASE COUNT         3176 a         1006 c         1619 g         2012 t
ORIGIN      
        1 caataaactg attgatatta aggaaaatat agatgatttt aatgaaatta gaaacgaata
       61 tagacaaatg ctcttaaatc aaagcagcaa agggaataat ggattatcaa agagtatgta
      121 cattaccttt accatagagg cggaggactt aaagcaggca aaaagtagat tagagcgaat
      181 ggaaatggat gtattaaaca actttaagca gatgggagtg aaagcctatg tgttagatgg
      241 agaggaaaga cttaaaacaa ttcatgacat tttaaatcca aatgataaac ttgttttttc
      301 ctttgaggat ttgaaataca gcggactgac gactaaggaa tacattgtac ctccgtcttt
      361 taacttttcc aagccgacgt attttaagac aggagaagtc tttgcggaag taaatttttt
      421 acagctttta gcatcagata ttaaagatga gatgttatca gagtttttgg cattggaaga
      481 aaatatgatt gttacttttc atatcagagc aatcgaccag atggaagcta ttaaacatgt
      541 aaaaagaaaa ataacggatt tggataagat gaagcttgag gaaaacaaaa aagctattcg
      601 tgcgggatat gatatggata tcttgccaag cgaccttgta acttatggtg cagaggcaaa
      661 gaacttgcta tcagaactac aaaaccatga tgaaaagatg tttctcataa caattttatt
      721 tatgaacacg agtaaaagta aggggaaact cgataatacg gtatttacct taaagtccat
      781 tgcaaataga cataattgta gtttgaaaaa cctaaattat agacaagaac aagggcttgt
      841 tgcaagcctt ccacttggga taaatgaagt ggagatagaa cgaggactta ccacaagtgc
      901 agcagctatt tttataccat ttacaacaga agaactcttt atcaagggag aaagcctata
      961 ttacggacta aatgcactaa gcagaaatat tattatggcg gacaggaaga aattaaagaa
     1021 cccaaatggt ctaatcttag gaacaccggg ttctggaaag tcctttgcag ccaaaagaga
     1081 gattactaat gcgtttttga ttacagatga tgatattatc attgcagatc cggaagcgga
     1141 atattctccg cttgtagagg cactaaaagg acaagttatc agaatttctc cgatttcaaa
     1201 agactatgtc aatccactgg acatcaatat tgactatgcg gatgaagata atcctttgtc
     1261 tttaaaatcc gactttattt tgtccctatt tgaattggtg gttggagaaa agaaattaag
     1321 tgcagaagaa atttctgtta tagaccgttg tttaccaatt ttatataaaa cctactttga
     1381 aaatcctgtg ccggaaaata tgccaatttt agaggattta tataatcttc ttcaaaaaca
     1441 ggaagaaata gtaggaaaaa agcttgcagt agaaatggag atctatgtaa aaggaagtct
     1501 taatgtattt aatcatagaa cgaatgtaga tacaaataac agagtggttt gctatgacat
     1561 caaagaactg ggaaaacagc ttaaaaagat aggaatgtta gttgtgcagg atcaagtttg
     1621 gaatagagtt acaattaaca gagcaagtaa aaaagcaacc agatattatg ttgatgaatt
     1681 tcatcttttg ttgaaagaac cgcaaacagc caattattcg attgaaatct ggaagcgttt
     1741 cagaaaatgg ggtggtatgc caacaggact tactcaaaat atcaaagacc ttcttgcaag
     1801 cccggagatt gaaaatattt ttgataatac ggattttatt ttaatgctta atcaagcagg
     1861 aacagatagg gatattttag ccaagaagct caatatctcc aagcatcagc tttcttatgt
     1921 aacaaattcg ggggaaggag aaggacttat cttttatgga aatacgattg ttccttttat
     1981 cgatcagttt ccaaaaaata caaaactata ttcactaatc acaaccaaac ctgaagaagt
     2041 aaaaaaggca ggtgaatagg atgagtgtga gcagaagtaa agaggaattc atcaaagaaa
     2101 atacaaataa aattatttgt tcggatgcac ttgaaacttt aagaaaaatt ccagacgaaa
     2161 gtataagctg ctgcattaca tctcccccat actacaggct cagaaactat cataaagaag
     2221 gtcagatagg aagagaatct acagtagaag aatacttgga tagattgtta caggtatttc
     2281 gtgaagtaag aagagcttta aaaaaagaag gtacttgctt tatcgtaatt ggagattctt
     2341 atgctgattc aggaggtgga aagggacaat acattgatcc taaatatcca aaggcaagaa
     2401 atggaagtaa cgctttagct acagaaaata tctcagggta caagtcaaaa gatttaatgg
     2461 gaataccttg gagattagcg ttacttctaa gagaggatgg ttggtatctg cgttctgata
     2521 ttatctggca taaggaaaat gctatgccgg aggcgtgtag agatagacct actcgttcct
     2581 atgaacatat ttttttactt acgaaatcac caaaatacta ttatgactat gatgctatgg
     2641 tagagccgat gaaagaagtc agtaaaaaaa gatatgtaag aggaagaaaa tcggataata
     2701 aatatctgaa agaaaattcc ggagcaaagt tgcaaaaaat caatgaagca agaaaatatg
     2761 gagaatataa gggcgataat gtcccgcagt ttcgtaataa aagagatatt tggactatca
     2821 ataccacatc ttttagaggc aatcattatg caacatttcc accgaaactt gttgagattt
     2881 gtatgattgc aggttgtcct aaaaatgaaa ttgtacttga tcctttcatt ggaagtggaa
     2941 cggtcggatt tgtggcactt cgtcataaca gaaagtacat tggaattgaa ttaaatgagg
     3001 agtatgtaaa tcttgcaaag aatagaatca gtgaggaggt gaaaaaattt aatgaagaac
     3061 aaaaacaaga ggtacaaaaa gaatagagaa aaactcttaa atcaagaaat acagtcttta
     3121 caatctcaaa ctcaagataa ttatgaaaca ggatcctcaa aaaatcagaa tgaaaccttg
     3181 ctgaaagacg aaacttacga taagaaacaa tttttatctg aaaagaagtt atccaatcat
     3241 ttggataata gacatataaa taattattcg gatagaacta tatcttctta ttgcttgtcg
     3301 gatacgggaa atataaatca aaataggtct tcctttcaag ctgaaaaaca taaaaaaaag
     3361 atgcaaaagc agataaataa atttcaaaag ggagaaaagg aagtctacga tcctttatca
     3421 aaagatatgg ataatgatgg tgtaatagac aggtatgatg tggattttag ggatagcaaa
     3481 gtatcatatc gaactcttac agatgatgaa aagtatgata ataaccaaaa tgataaagga
     3541 aaaaattata atgactatgt aaaaaatcca aaatctaaga ataagaggta taaaaattat
     3601 gtaaaagaca cattttctaa ggaaagaatg aaatcagaaa accagaagaa atatgtgagg
     3661 agcaactttg atgatgaaga gttcacaaga aataaggata cgaaaaataa tttatttcag
     3721 gacgtaaata ataaaagaaa aactaccgat aaaaattcat cacgaaaaag aaaaggaaaa
     3781 tttgaaaata aggaaaagaa aatatccaag ttacagcaga aaaagcaaag acaagagcaa
     3841 aaactgaaaa ataagggaat tgacgggaaa agtcaaagtg ctaaaagtgc agtaatagca
     3901 acgggtatgg caaagaggta tttggaaagt ggaaaagagg acaatgccgg agtaggtact
     3961 gcttataagg ttacagatca ggtcgaaaat atttcaagga aaatatatta tcatggaaaa
     4021 aagaaaaatt taaaaaggca aaaaaagata acaaaattag gtaaaagcat tgataaacag
     4081 gagaagaaac tcttttttca aaagaatatg gaagagatga aaaaaagcgt ggattaccaa
     4141 aatacctcaa ggctcagaca attctttaag agaaggcaat ataaaaatca gattcaaaag
     4201 aagtataaag atagtgtgaa aaacagaata aaaaaatcct ttatagaggg cagtaaaaga
     4261 tttggcgaat ttgtaaaggg cagagggaaa aagataatat ttctatcact tttagcggta
     4321 ggaatatttt ttatgttatt tcaggctggg agcatgatga tgaatatggg aacgggaatg
     4381 gtaagtaata ctgtttcaac cacctactta tcatcagaag acaccttaaa agaaatcaat
     4441 cagaggtttt catctttgga acaggctttg caagaagaaa tggacagtgt ggaggaaaat
     4501 catccgggct atgatgaata tattatcaaa ggaaaagaga aaattggtca taatgttcat
     4561 gaactcttgt catatatcac agcccgttat ggaattgtaa agaatatttc tgaagtagaa
     4621 agtgaactaa aacatctgtt tcaaaaaatg tatacgctga cttataaaga agagattgaa
     4681 atcagatata gaactgttac atccagctat acggatgctg atggcaatga acatactgaa
     4741 agtcatgaag agccgtatga gtataggaaa ctcattgtaa ccttagaaaa aagagagatg
     4801 gacggaatta ttagagaagc atttaagcgt tatcctaata atttggcaca ctatgaaact
     4861 ttatttttga cacaaggaaa tatgggagaa gtatttggaa atattgacct tataaattca
     4921 aatggtggaa ttggtggtgg taaagagtat gaagcatcaa gtgaagtgca aaagaaaata
     4981 gtgaatgccg cttatattac accatctcca ggagcaggtt ggtgtgccat gtgggtatca
     5041 caggtctatc aaaatgcagg acttggattt attggaggaa atgcttgtga tatgtatcga
     5101 aattatactt ttacttctga taggtcaaag ttaaaggttg gaatgcttgt tgcagttgaa
     5161 agtagcagta gtggtagcag tttaggtgtt acctatggtc atgtaggtat ttatatcgga
     5221 gatggaaaag taatggataa tatcggacac ataagagtaa ctaccctaga tgattggatt
     5281 gcaacatttt gcaaacatca ccctgtaggt tttggatttc caccatcagt acaaaaataa
     5341 ggagggaata ttttgaataa aaaatataga aaaaatatag aaaagcaaaa agatattcag
     5401 aaaaaaatag aagaactcca gttaaaacag gagatgttaa aagaagaaca ggaagagatg
     5461 gaaaatattg aggttttaaa ggaataccga agtattgaca tttctattga cgatttttta
     5521 gaaatgatga gacgttataa aaaagaggaa aaacaagaaa aaatgaagtt acaggaaatg
     5581 agaaatacag aaaatcataa taatatggag gaaaatcatg aaaatcaaat ggaagaataa
     5641 aaaaatggcg ataacattgt ccggagtaat ctttttgata cttgctttac ttggaacaat
     5701 gcttttcaat caccagattg tttttgcaca aggtagttta atcccgacac tgattagtcc
     5761 cacagaagtt ttagctcaaa ctaaagtgga ggttaagata aaatatatat ttaaggatga
     5821 gagtgtatat aaggaagaaa taattgaagt agaaaccggg caagttcttg acagtgggga
     5881 cctaccaatg ttagaggata atatgaaatt tattgacgaa tttttgttct ataaagtaaa
     5941 gggagacggt acagatgaga ttatccgtaa agtagaaaaa attacagtta aggataaaga
     6001 aattcagaca gaagaggaaa agccaaaaca ggacgaaagc actgagacgg aagataaaaa
     6061 aacagaagat aagggaacac agacagagct ttctaaagat gatatttcca aaatggaaaa
     6121 agaggcaaaa gagcttcagg ataaacttga taaattaaat ggtgaaatca gggataaaga
     6181 caaactaagc gataaacaga aagaaaaaat caaagacctt gaagctgaga ttgaaagtct
     6241 gaaagaaaaa atgaagaaag ataagggaaa taaagactta tcagaagata tgaaaaagga
     6301 aatagataag ctgacggaaa aggtgaaaga gcttgagaaa aagccaactg aaacaaacaa
     6361 agctcctgta acatcacagt ctgttacacc gattagtcct atttcaggga ttaagacaag
     6421 ctcaggtatt tcttctcaaa caccacagag ttccggtaaa ggttcatctg atgcagtaag
     6481 ctccggcaat actacaaaag atacaggtaa aactgaatca aaggagaaag aaaaggaagt
     6541 tcgctatccc aataagctga caccgaaagc tcctgctaat aacagtagtc aggattcatc
     6601 aatggacggt gcaagtagca atgtaaatac caataagggt gtggcttcag ctccgtcaaa
     6661 ggcaagagga actgttacag aaaataaaga taatgcgaat aatgattatc caattcatca
     6721 tggggatagc agcgataaca aagaagcaga taagtattca gcagatgcaa gacaatttat
     6781 tactttccag acaaaatccg gaaagacatt tcatttaatc atcaatcacg atgagcaaag
     6841 tgaaaatgta atgcttttga ctgaagtatc tgaagatgat cttctgaata tggtagagaa
     6901 gaaggaaaac ccgcaagaag aaatcaaaaa aatggaagaa acggtaccgg aaagcgaagt
     6961 aaaaaaagaa gagccgaaaa aggaagaagg taaaggtagc ggctcatata tttttttagg
     7021 aatcatcgtt cttgcagtag ttggagcagg atattacttt aaaatctaca agaaaaagta
     7081 ggaagatgat gattatgatg aagatgagga agaatatgat gaatttgaag atgagtatga
     7141 aaaagaggac gatacagaag atttggaaga aacagtagaa gaacagcata acatagatga
     7201 tatggcaatc gactcttatg atgaagaaga tgaggaataa agttataaaa agagaaatgt
     7261 aaaccctgat gttgcgttta cacttaaaaa atggtataat gcaagtgtaa acgcaacaaa
     7321 gggggtggat gggatgaatt atgaaaataa aattgaaaaa tatttgaagc aatcaggtgg
     7381 aattattaca acagcatact gtaaggaaaa taatataccg acgatatatc tcagtcgact
     7441 attgaaagat gggagattgt caaaagtaag aaaaggaatt tatataacga aagatgggga
     7501 ttacgatgag tattatttct ttcaacatca gtataaaaag gcgatatttt cttatgaaac
     7561 agcactttac ctgcttggac aaacagataa aattccttgg agtatcgatg taaccgttta
     7621 taacggatat aaatttaatg aaaaaccgaa cggtttcaat gttcattatg taaaaaaatc
     7681 aatttatgac ttaggggtaa cccaaaaacc tacaatgttt ggaaataaag ttaaggtata
     7741 ttcatatgag aggacactct gtgattttat tgctcataaa gaagaaatgg atatagaggt
     7801 ttatgtaaaa ctt
//
LOCUS       DARYYD010000076         7808 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.077, whole genome shotgun sequence.
ACCESSION   DARYYD010000076 DARYYD010000000
VERSION     DARYYD010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7808
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.077"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            32..724
                     /locus_tag="TV188_001773"
     CDS             32..724
                     /locus_tag="TV188_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1535100.1"
                     /translation="MFSGIQLKTARLSRHISQEQLGQLLGVNKMTISNWEKEKNRPNQ
                     KHFEELVSIFQLPAEYFYQENRLLLPYSQLSASNKEKVISYSESLLEQKEKIIALPAK
                     KKTLYPYRVYERLSAGTGYSYFGDGNFDVVFYDEQLDYDFASWVFGDSMEPTYLNGEV
                     VLIKQDSFDYDGAIYAVEWEEQTYIKKVYREENGLRLVSLNKKYPDKFASFDDNPRII
                     GKIIANFMPLDV"
     gene            complement(1100..1576)
                     /locus_tag="TV188_001774"
                     /pseudo
     CDS             complement(1100..1576)
                     /locus_tag="TV188_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515631.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1789..3351)
                     /gene="guaA"
                     /locus_tag="TV188_001775"
     CDS             complement(1789..3351)
                     /gene="guaA"
                     /locus_tag="TV188_001775"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEL1535101.1"
                     /translation="MTEISMLNDIQKIIVLDYGSQYNQLIARRIREFGVFSELKSHHI
                     TAQELRDINPIGIVLSGGPNSVYATDAFGIDPEIFELGIPILGICYGMQLITHTLGGK
                     VVPAGQAGHREYGQSSLRLRSASALFAGTPDEQLVLMSHGDAVTEIPEGFHLVGDSND
                     CPYAAMENTKKRLYGIQFHPEVRHSVYGNDILKNFAISICGGRGDWSMDNFIDMQIAK
                     IRETVGDRKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHGLLRKNEGDQVMEMLG
                     GRFGLNIIRVDASKRFLDLLAGVEDPEKKRKIIGNEFVYVFDDEASKLKGVDFLAQGT
                     LYTDIIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGTALGMPDEV
                     VWRQPFPGPGLAIRVMGEITAEKLETVRESDAILREEIAKAGLERDVWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAQLPWEVLKKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3638..4336
                     /locus_tag="TV188_001776"
     CDS             3638..4336
                     /locus_tag="TV188_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1535102.1"
                     /translation="MLPAYIKIHDAIKKDIEKEVWTIGSRLPSERDLAEHFEVSRMTL
                     RQAITLLVEEGILERRVGSGTYVASHRVQERMRGTTSFTEIVNSQGRKPSSKLISYQR
                     QLASDTEINQLHLEESDYVIRMERIRYADKVPLVYEVASIPEKFIKNVKKTDITEHFF
                     QTLTSNGYEIGKSQQTIYAKIASERVASYLEVAKGHAILALTQVSFFTDGRPFEYVRS
                     QYVGDRFEFYLENN"
     gene            4548..4880
                     /locus_tag="TV188_001777"
     CDS             4548..4880
                     /locus_tag="TV188_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEL1535103.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEAYEMKLHMYSDYIVRSEIFDDILAKYPSDHYLRDKISI
                     LTSIDNRD"
     gene            4895..6466
                     /gene="ffh"
                     /locus_tag="TV188_001778"
     CDS             4895..6466
                     /gene="ffh"
                     /locus_tag="TV188_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEL1535104.1"
                     /translation="MAFESLTQRLQDVFKHIRGKKTLSEADVQEVTKEIRLALLEADV
                     ALPVVKTFIKRIRERAVGHEIIDTLDPTQQILKIVNEELTGILGSETAELDKSPKIPT
                     VIMMVGLQGAGKTTFAGKLANKLIKEENARPLMIAADIYRPAAIDQLKTLGQQINVPV
                     FDMGTNHSAVDIVANGLAQAKENRHDYVLIDTAGRLQIDEKLMGELREVKALAKPNEI
                     LLVVDSMIGQEAANVAYEFNNQLDITGVVLTKIDGDTRGGAALSIREITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDLLTLIEKASQEYDEKKSLELAAKMRENTFDFNDF
                     IEQLDQVQNMGPMEDLLKMIPGMATNPALANIKVDDKQIARKRAIVSSMTPEEREQPE
                     LLTPSRRRRIAAGSGNSFVEVNKFIKDFNQAKAMMQGVMSGDMTKMMKQMGINPNNLP
                     KNMPNMPGGMPDMSALEGMMGQGGLPDMSALGGDMDMSQLFGGGLKGKIGQFAMKQAM
                     KRQANKIKKAKKKRK"
     gene            complement(6619..>7808)
                     /locus_tag="TV188_001779"
     CDS             complement(6619..>7808)
                     /locus_tag="TV188_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoacyltransferase"
                     /protein_id="HEL1535105.1"
                     /translation="SAQEHDQFVKQHQQVNLLQSSSWAAVKNQWQNERIGIFQGDNQV
                     ASMSLLIKPLPFGMTMIYIPRGPVMDYTNADLVAFTIKTLKAYGKKKRALLIKFDPMI
                     LLKQHQLGEKAPDNSKALTIIKHLKRFGAHWTGPTTKLSDTIQPRFQANCYTNADIEA
                     SFPKHTKRLMKDARQRGVIAYRGNQSDLHTFADLISLTEKRKGVALRNEAYFRQLMTT
                     YGDNAYLHLAKVNLPEKLKNYELQLKAVEQELAQTQAHQKKRLARLTDQKQSLQRYLS
                     EFKDFLDKYPDEVVIAGILSISYGNTMEMLYAGMNDDFKKFYPQYLLYPKVFMDAYHD
                     DIAWANMGGIDGSFKDGLTAFKSNFSPTIEEFIGEFNLAISPFYHLANLLYKIRKQLK
                     HRH"
BASE COUNT         2450 a         1526 c         1480 g         2352 t
ORIGIN      
        1 tagagtatac tgacaaagga gatttatgct gatgttttct ggtattcaat taaaaacagc
       61 acgtttatca aggcatatta gccaagaaca gctaggacag cttttaggag ttaataaaat
      121 gactatttcc aattgggaaa aggagaaaaa tagaccaaat caaaagcatt ttgaagagct
      181 tgtgagcatt tttcaattac ctgctgagta cttttatcaa gaaaatcgtc ttttacttcc
      241 ctatagtcag ttaagcgcct ctaataaaga aaaagttatc agctattctg agagcttact
      301 tgaacaaaaa gaaaaaataa ttgctttacc agctaagaaa aagacacttt acccttatcg
      361 tgtttatgaa aggttgtctg cagggactgg ctattcttac tttggtgatg gtaattttga
      421 tgttgtcttt tacgatgagc agttagatta tgattttgct tcatgggttt ttggtgactc
      481 catggagcca acctatttga atggcgaggt tgttctcatc aaacaggata gctttgatta
      541 tgacggtgct atctatgctg ttgagtggga agaacaaacc tatatcaaaa aagtatatcg
      601 tgaagaaaat ggtctgcgtt tggtttcatt gaacaaaaaa taccctgata aattcgcttc
      661 ctttgatgac aatccgcgta ttattggaaa aatcattgcc aactttatgc ccttagatgt
      721 ataagccttt gtattagctt aaaagcatga ctgttgtaca accaaactca ttgcatgaca
      781 ttggtgcatt atttttgaag tggcttctac ttctttgatt tacttttctg cattaaaaag
      841 cccattaaag gtttttgaaa cttattactt agacaaaggc tctattaaaa atcataacca
      901 accggtggtg gtttatttgt catgtacctt gcattttgtg acagacttca taaaacgaac
      961 aaaacacatc gctaaaagat tttaccatct taaagttatg tgttttttgt ataaaaactt
     1021 atctatatgc ttgattaacc aactgagata aatagattat tatttcatag agaagtttgt
     1081 tatctaatcc aaataatcgt attatcctct taagttcctc aacattataa ccatcacaat
     1141 ctgttggcag tttatttttt tcaagccact tatcaaccac tgctattccc aaagaaattg
     1201 aaaaatcttt ttctttatca aacttacaca attccactgc caaagtcaat acaaaattcc
     1261 tgtgaatatt atcgtaattt tcatcaaata attgcctttc caaacccaca atagatagcc
     1321 gactaaatat gtatctccct atttcttcgt caataccttc agtagcctta atagcttctt
     1381 ggacaacatt attccagaaa gcatttttat tacgctcttc tataaaagtt ttaagtttca
     1441 ttttgaaaat atcagtaatt tgaccaactg ctttatcaat aacctatgaa acaatattct
     1501 tcatcattat gattttctcc tcgtatacat aaataattgt atctttgcta tataattgtg
     1561 gtatctcttc aatcaaccaa tattgttctt aaactattcc ctcaaaagcc ttccaccaaa
     1621 acgatggaag gcttttaaac cattcaccta aattcaacaa ctcccttttg aacttgctat
     1681 tttagctttt tagtatcaaa gcagtatcac tcaagagttt tttgtttcca caaaccgcaa
     1741 aaacccactg ttttcaacac tttcatggca gtaatatatt tgcttctgtc actcccactc
     1801 aacggttgct ggtggtttgc tggtgatgtc gtagacaatg cgattaacgt ggtcgacttc
     1861 attgacaatt cgaactgaga ttttctttag aacttcccaa ggcaattggg caaagtctgc
     1921 tgtcatacca tcaattgagg tgatagcacg aatagcgatg gtatagtcat aggtgcgacc
     1981 atctcccata actccgacgg aacgaacacc tgtgttaact gtaaaatatt gccacacatc
     2041 acgctcaagt cctgctttag caatttcttc tcgaaggata gcatctgact cgcgaactgt
     2101 ttcaagcttt tctgctgtga tctctcccat gacgcgaatg gcaaggcctg ggcctgggaa
     2161 aggctgacgc cagacgactt catctggcat accaagggcc gtaccaagag cacgaacctc
     2221 atccttaaag agtgtattga ggggttcgat taattcaaac tgcatatcct ctggcagacc
     2281 accaacattg tggtgagatt ttatcgtttg agcagtttct gttccagatt caatgatgtc
     2341 tgtgtaaagc gttccttgtg caaggaagtc aacgccctta agcttgctag cctcgtcatc
     2401 aaagacgtaa acaaactcat taccgataat tttacgtttt ttctcaggat cctcaacgcc
     2461 tgcaagaaga tctaaaaagc gctttgaggc atcaacacga ataatattga gaccaaatct
     2521 tccaccaagc atttccataa cttggtcacc ttcattttta cgaagaagtc catggtcaac
     2581 aaagatacag gttaattgat ctccgatagc tttttgtaaa aggacaccaa caactgaaga
     2641 atcaacacca ccagacaaac ctagcaaaac cttacgatct ccgactgttt cgcgaatttt
     2701 agcaatttgc atgtcaataa aattatccat tgaccaatca ccacgtccac cacagataga
     2761 gatagcaaag ttcttcaaaa tatcattacc atagacagag tgtcttacct ctgggtggaa
     2821 ttggataccg tagagcctct tttttgtatt ttccatagca gcgtaagggc aatcgttaga
     2881 atctcctaca agatgaaagc cctctgggat ttctgtaaca gcatcaccat gactcatcaa
     2941 aacaagctgc tcatctggag tgcccgcaaa taatgctgat gcagaacgta aacgtaatga
     3001 tgattgacca tattctcggt gacctgcttg accagctggg actaccttac ctcctaaggt
     3061 atgtgtgatt agctgcatgc catagcaaat ccctaaaatt ggaatcccta attcaaagat
     3121 ttcaggatca ataccaaagg catcagttgc ataaacagaa tttggcccac cagacaggac
     3181 aatcccgatt ggattgatgt cacgaagctc ttgcgcagtg atgtgatggc ttttgagctc
     3241 agaaaaaaca ccaaactccc gaatacgtct tgcaatcagt tgattgtact gactaccata
     3301 atcaagaacg ataatttttt gaatatcatt caacattgaa atttcagtca ttataaccct
     3361 ttcattatat accagaacct tgttagctga tagttttcaa ttaattgtag catattttca
     3421 ctaaaaaggc attagctttt caggtgatgt gatgaaaaaa taagcttttt gcagagatat
     3481 taaaatgaat gacctcaact atcttatgta tgactactat tgtcagtctt agcatgaaaa
     3541 agctgattga tgatgagtgt ttttggtaat aattgggctg ctatttaggc tgaaaatatg
     3601 ataaaataaa accatcatca ccctcaagga gtaaagcatg ctgccagctt atataaaaat
     3661 tcatgacgct attaaaaaag acatcgaaaa agaagtttgg actattggta gtcgcctgcc
     3721 aagcgaacga gatttagcag aacattttga ggtcagtcgc atgacgttgc gtcaggcaat
     3781 aacactgctt gtagaggagg gaattctaga aaggcgtgtt ggtagtggta cttatgttgc
     3841 cagccatcgc gtacaagaga gaatgcgtgg gaccactagc tttacagaga tcgtgaattc
     3901 tcagggacgt aagccatctt caaaactgat ttcctatcaa cgtcagctag caagtgatac
     3961 agaaataaat caattgcact tagaagaatc agattacgtt attcgaatgg agcgcattcg
     4021 ttatgcagat aaggttccct tagtttacga ggtagcatct attcctgaga aatttattaa
     4081 aaatgtcaaa aaaactgata ttacagagca ctttttccaa accctaacct caaacggtta
     4141 tgaaatcggc aaaagtcaac aaaccattta cgcgaaaata gccagtgagc gtgtcgcctc
     4201 ttatctagag gtcgctaagg ggcatgctat tttagcattg actcaggttt ccttttttac
     4261 agacggtagg ccctttgaat atgtgcgtag ccaatatgta ggtgatcgct ttgaatttta
     4321 tttagaaaat aattaatcat aagcaatgat gtttaaataa cattgatagg aagtggctca
     4381 ccacttcttt ttttcaacac ttgtcaagta tatcaatatt tcaagaacag ttattaaaac
     4441 aagctactat tatcctcatt tttgctctaa gaaagcttcc tgataaaagg ctgatcgcta
     4501 tcatttacca ctgttaaaaa tgctcatgat gtgataaaat gaagattatg gaaattgaaa
     4561 aaacaaaccg aatgaatgct ctttttgaat tttatgctgc cttattgact gataaacaga
     4621 tgaactatat cgagctctat tacgctgatg attatagtct ggctgaaatt gctgaagaat
     4681 tcggtgtcag ccgccaagca gtttatgata atattaagcg cactgaaaaa attctggaag
     4741 cctatgaaat gaagcttcat atgtattcag attatattgt acgtagtgaa atatttgatg
     4801 atattcttgc aaaatatccc agtgaccact atttacgtga caaaatttcc attttaacta
     4861 gtattgacaa cagagattaa gaggagttat agctatggca tttgaaagcc taacccaacg
     4921 tttacaggac gtttttaagc acattcgtgg taaaaaaacc ttatctgaag ccgatgttca
     4981 ggaagtgacc aaggagattc gtctagcctt attagaggca gatgttgcac ttccagttgt
     5041 taagaccttt atcaagcgta tacgtgagcg agctgttggc cacgaaatta ttgataccct
     5101 tgatccaacg caacaaatac ttaaaattgt taatgaggaa ttaactggta tcttaggatc
     5161 agaaaccgcg gagcttgata aatcacctaa aatccctact gtcatcatga tggtgggctt
     5221 gcagggagct ggtaaaacga cctttgcagg aaaattagcc aataagctca tcaaggaaga
     5281 aaatgctcgt ccattgatga ttgcagcaga catctatcgt ccggctgcta ttgaccagtt
     5341 gaaaaccttg ggacagcaaa taaatgttcc tgtttttgat atggggacaa atcattcagc
     5401 agttgatatt gttgccaatg gtttggcaca ggcaaaagag aaccgtcatg actatgtttt
     5461 gattgatacg gcaggacggt tacaaattga tgagaaacta atgggcgagc ttcgtgaggt
     5521 taaagcacta gctaaaccaa acgaaatcct tcttgttgtt gacagcatga tcggacaaga
     5581 agctgccaac gttgcctatg aatttaacaa tcagctcgat atcactggag tagtgttaac
     5641 aaagattgac ggtgatactc gtggtggtgc ggccctttct atacgtgaaa taactggtaa
     5701 gccaatcaaa tttaccggaa ctggtgaaaa aatcaccgat attgaaacct tccatccaga
     5761 ccgtatgtca agtcgtatct tgggaatggg agaccttctt accttgatcg aaaaagcaag
     5821 tcaggaatat gatgagaaaa aatcattaga gcttgccgca aaaatgcgtg agaatacctt
     5881 tgattttaat gactttatcg agcaattaga ccaagtgcaa aacatggggc caatggaaga
     5941 tctgttaaaa atgattccag gtatggcaac taatcctgct ctagccaata ttaaggttga
     6001 cgacaagcaa attgctcgca agcgtgctat cgtttcttct atgacacctg aggagcgtga
     6061 gcagccagag cttttaacac caagtcgccg ccgtcgcatt gcagctggat caggtaatag
     6121 tttcgttgaa gtcaacaaat ttattaaaga ttttaaccaa gccaaagcca tgatgcaggg
     6181 tgtcatgtca ggtgatatga ctaaaatgat gaaacaaatg ggaatcaacc ctaataacct
     6241 ccctaaaaac atgccaaata tgccaggagg catgcctgat atgtctgccc ttgaaggaat
     6301 gatggggcaa ggtggtttac ctgacatgtc tgcattgggt ggtgatatgg atatgagcca
     6361 gctctttgga ggtggtctaa agggtaagat tggtcaattt gccatgaagc aggccatgaa
     6421 gcgtcaagct aataagatta aaaaggccaa gaaaaaacga aaatagacta aaagaatggt
     6481 tgccttgtat tctgcctcta atcgttagat gctattctaa tttggagtgc aggtcagtag
     6541 cgaccatctt ttttataaat acaatcacta gatctttggt tctaaccatt aaacatgata
     6601 tcatttcact attagctgtt agtgcctgtg ctttaattgc tttctgatct tatatagcaa
     6661 attagccaag tgataaaaag gactgattgc taggttgaat tctccaataa actcttcgat
     6721 agttggactg aaattggact taaatgctgt caatccgtcc ttgaaggagc catcaatgcc
     6781 gcccatattc gcccaagcta tatcatcatg ataggcatcc ataaagactt taggataaag
     6841 caggtactga ggataaaact ttttaaagtc atcattcatg ccagcataga gcatttccat
     6901 cgtgttgcca tatgaaatcg ataaaatgcc cgcaatgaca acctcatctg gatatttatc
     6961 caagaagtcc ttgaattctg atagataacg ctgaagcgat tgcttttgat ctgttagtct
     7021 agccagtcgc tttttttgat gcgcttgcgt ttgagcaagc tcttgttcaa cagctttcag
     7081 ctgaagctcg taattcttga gtttttctgg aagattaacc tttgctaaat gcaaataagc
     7141 attgtcgcca taagtcgtca tcagctgtct aaaataagct tcgtttctta gagcaactcc
     7201 ttttctcttt tcagttaaag agataaggtc agcaaatgta tggagatcag actgattacc
     7261 tcgataagct atcacgccac gttgcctagc atccttcatc aatcgcttgg tatgcttagg
     7321 aaaggacgct tcaatatcag cattagtgta acaatttgct tgaaaacgcg gctgaatagt
     7381 atcagatagc ttggttgttg ggcctgtcca atgggcacca aatcgcttta aatgcttaat
     7441 aatggtcaga gccttggaat tatcaggtgc tttctcacca agctgatgct gctttagcag
     7501 aatcatagga tcaaatttaa tcaaaagagc tctttttttc ttaccatatg ccttcaaggt
     7561 tttaatcgta aatgccacta gatcagcatt ggtatagtcc atcactggac ctcttggaat
     7621 ataaatcatc gtcataccaa acggcaaagg cttaatcagc aaggacatag aagccacctg
     7681 attatctccc tgaaaaatac cgatgcgttc attttgccac tgatttttaa cagctgccca
     7741 tgagctgctc tgcaagaggt taacctgctg gtgctgtttg acaaattggt catgctcttg
     7801 agctgaaa
//
LOCUS       DARYYD010000077         7801 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.078, whole genome shotgun sequence.
ACCESSION   DARYYD010000077 DARYYD010000000
VERSION     DARYYD010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7801
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.078"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..1037)
                     /locus_tag="TV188_001780"
     CDS             complement(<1..1037)
                     /locus_tag="TV188_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634-like element ISSeq4 family transposase"
                     /protein_id="HEL1535106.1"
                     /translation="MAFIKTTTNKEGRTHVYLVEGYRKDGKVKQRILKKFGLLDELEL
                     EEPGILERLKREAKEDTLNNPKVLQVSYDLLAPMNQPDQSYGWMVLDNLFESLGLTAF
                     LKGIKTKSEYDLVQVLKLLVFQRILRPDSKLATYASQADLFGHWDISLNAIYRSLNKL
                     NTLKDDLQHHLHKVVSQMIKREASLVFYDVTNYYFETDIPDNELVSENGEILQEGLRR
                     RGPSKEHRPKPIVQLGLFRDTNGIPISYKLFRGNQTDPVTYLPAVEEVKKQFGIERLI
                     VVADKAMNSMANVSEMLKQEDGWLFSQKHRGRRGAPKDIQEHILDSSDWQFNPELTFA
                     KKSYIRERKLG"
     gene            complement(1201..4311)
                     /locus_tag="TV188_001781"
     CDS             complement(1201..4311)
                     /locus_tag="TV188_001781"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEL1535107.1"
                     /translation="MFAQLDTKTVYSFMDSLIDLDHYFKQAKRLGYQAIGIMDQDNLY
                     GAYHFIKGCQRHGLQPILGLEVAITVKEQALTLKLVAKNDTGYQQLLKLSTEKMSGDL
                     DLDTLVQYLEGIAVIVPFSQSLRDLGLPFDYFIGIDEASDLSKIDSTERLIPLRTVRY
                     FDNAETETLQMLHAIRDNISLADTALVAKDQFLAPCQEMTAIFQEKCPEALVNLVNLT
                     ASIAYHFDTDLKLPRFNRDKPAKEELRELTESGLREKQLWKEPYQFRLAEELAIISDM
                     GFDDYFLIVWDLLRFGRSRGYYMGMGRGSAAGSLVAYSLRITGIDPVKNNLLFERFLN
                     KERYSMPDIDIDLPDIYRSEFLHYVRDRYGSEHSAQIVTFSTFGPKQAVRDVFKRFGV
                     PEYELTSLTKKIGFKDTLSTVYEKNIAFRQTINSRLEFQKAFEIAKRIEGNPRQTSIH
                     AAGIVMSDDHLTNHIPLKKGEDMMVTQYDASAVEANGLLKMDFLGLRNLTLVQKMQEK
                     VVNDYGLSIDIEAINLEDPETIALFARGDTKGIFQFEQHGAISLLKRIKPTSFEEIVA
                     TTSLNRPGASDYTQNFIKRRQGQENIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYA
                     GFTLGKADLLRRAMSKKNLVEMQRMQEDFLTGARALGRSEETARLLFARMEKFAGYGF
                     NRSHAFAYAALAFQLAYFKAHYPEVFFDVMMNYSSSDYITDALDFGFEAAQVTINTIP
                     FNDKIERHKIYMGLKNIKGLPREFSYWIIENRPFTSVESFLCSIPEKYQKTSFLEPLI
                     KIGLFDGFEKNRQKIINNLEGLLTFVNELGSLFADSSFSWVETEDYSAAEKYYFEQDL
                     LGVGMSKHPLLAVAEKSTVAVTPITKLVKDTEATLLVQIDAIRVIRTKSSGQQMAFLS
                     VTDTKQKLDVTLFPEQYAVYKQDLKEGHIYYINGRVKERDNRLQLVCHQLRLAQSQRY
                     WLLVENHQHDAAISDILTAFSGETPVIIHYQEGKETLELNHIRVDVSKDLEEAISPYV
                     LKTVFR"
     gene            4553..4924
                     /locus_tag="TV188_001782"
     CDS             4553..4924
                     /locus_tag="TV188_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEL1535108.1"
                     /translation="MSWKFDEKSPIYAQIAQHIMLQIVSQEIKSGDQLPTVREYAEIA
                     GVNPNTMQRALTELDREGIVYSQRTAGRFVTDNQELIARKRRELAINELKSFISNMIK
                     IGFERSEIIPVLSTFLEEGSN"
     gene            4924..5622
                     /locus_tag="TV188_001783"
     CDS             4924..5622
                     /locus_tag="TV188_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1535109.1"
                     /translation="MAQLLQLHHVSKSYKKQLAIDDLTITIPSGKIIGLLGPNGSGKT
                     TLIKLINGLLQPDKGDIVIDGFRPSVETKKIISYLPDTTYLNESMKIKDMLDFFGDFY
                     ADFDRDKATSLLKDLDLDAEERFKNLSKGNKEKAQLILVMSRKAKLYILDEPIGGVDP
                     AARDYILKTIINNYSEQASVIISTHLISDIEPVLDEAIFLKNGKLCLSGNADDLRVQH
                     QQSIDSLFREIYKV"
     gene            5632..6426
                     /locus_tag="TV188_001784"
     CDS             5632..6426
                     /locus_tag="TV188_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1535110.1"
                     /translation="MFGKLLKYEFRSIGKWYFALNAGVIAIAIVLSFTINTLTNNPDE
                     VGLTTSLANKMVPLTLSLTFGSLIAGSFLSTLLIIINRFNKNVFGREGYLTLTLPVTA
                     HQIILSKLLASFVCSIFNGINLLIGIFILIAPTVDFTYLLKVLKTIMKPENLVENASI
                     LIYMLLSTITSILLIYLAISIGQLFSNRRGLMAFCAYFILVIIIIVVMTYLNDAFFTV
                     NPNSSDSLLYFGDHTAISILNIEQLVEGIILYVATHFIIKNKLNIQ"
     gene            complement(6473..7084)
                     /locus_tag="TV188_001785"
     CDS             complement(6473..7084)
                     /locus_tag="TV188_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEL1535111.1"
                     /translation="MRNNELKPYVIWQKVIKLLGSLALVGSFLLAFWFYRLGILNDSN
                     ALKDLVHSHKVFGPLVFVGVQIVQIVFPIIPGGMTTIAGFLIFGPLLGFLYNYVGIFI
                     GSVILFLLVKTYGRRFILLFIEEQTFYKYERKLEMPYYERLFILCMLSPISPADIMVM
                     ITGLTEMSLKRFVTIILITKPLSIIGYSYLFIFGKDLILWFFH"
     gene            7175..7523
                     /gene="ssrA"
                     /locus_tag="TV188_001786"
     tmRNA           7175..7523
                     /gene="ssrA"
                     /locus_tag="TV188_001786"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
BASE COUNT         2392 a         1684 c         1398 g         2327 t
ORIGIN      
        1 ttccctaact tccgttcacg gatataagat ttcttagcga aggtaagttc tgggttaaat
       61 tgccaatccg atgaatcaag gatgtgttct tgaatatctt ttggagctcc tcggcgtccg
      121 cgatgtttct gtgagaagag ccagccatct tcttgcttga gcatttctga aacattagcc
      181 atactattca tcgccttatc ggcgactaca attaaccgct caattccaaa ttgttttttg
      241 acttcctcaa ccgctggaag ataggtaaca ggatcggttt gattacctcg aaacagttta
      301 tagctaatcg gaataccgtt ggtatcccta aagagtccta attgcacaat gggttttgga
      361 cggtgttcct tactcggacc acgtcttcga agcccttctt gtagtatctc tccattttct
      421 gaaaccaact cgttatctgg aatatctgtc tcaaaataat aattggtgac atcgtagaaa
      481 acgagactgg cttcacgttt gatcatctga ctcactacct tgtgaagatg atgttgaaga
      541 tcatctttca aggtgttcaa tttgttcaag gagcgataaa tggcatttaa gctgatgtcc
      601 caatggccaa ataagtctgc ttgagaggca taggtggcaa gtttactatc tggtcggaga
      661 attctctgaa aaactaatag ctttagcact tgcactaagt catactcaga cttcgttttg
      721 atacccttta aaaaggctgt gagccccaga gattcgaaga gattatccaa aaccatccaa
      781 ccataagatt gatccggttg gttcatgggg gcaaggaggt cataggaaac ctggagtacc
      841 ttagggttat ttaaagtatc ttctttagct tcgcgcttaa gacgctcaag aatccctggt
      901 tcttccaatt caagctcatc taagagacca aattttttaa ggatacgctg tttgacctta
      961 ccatctttac gatacccttc tacaaggtag acatgcgtcc taccttcttt attcgttgtt
     1021 gttttaataa aagccatagt ttattataac atatataacc atacacaaca agaaaaagcg
     1081 ttaaaattta ttaaaaaacc ttactctacc aagaggttga gtaaggtgtg gactaaaaca
     1141 agtgataaag tcgggattat agcacattcg tttgcaaatt acttcactaa ttcgctattt
     1201 ttatcgaaaa accgttttca acacgtaggg gctaatagcc tcctccaaat ccttactaac
     1261 atcaacccta atatggttta actctaaggt ttctttgcct tcttgataat ggataataac
     1321 aggagtctcc cctgaaaagg ctgttaatat gtcagaaata gcagcatcat gctgatggtt
     1381 ttcaaccaat agccaatacc tttgactctg agctaatcga agctggtgac agactagctg
     1441 caagcggtta tctctttctt ttaccctgcc attgatatag taaatatgcc cctcttttag
     1501 gtcttgctta tagacagcat attgctcagg aaaaagggta acatctaatt tctgtttggt
     1561 atcagtaaca ctcaaaaagg ccatctgctg tccgcttgat tttgtccgaa taaccctgat
     1621 cgcatctatt tgaaccagca aagtagcttc tgtatccttc actaactttg tgattggtgt
     1681 gactgctact gtgctttttt cagcgacagc tagcaagggg tgcttgctca tgccaacacc
     1741 aagcaaatcc tgctcaaagt aatatttctc agcagctgaa taatcctcag tctctaccca
     1801 gctaaaggag gaatccgcaa aaagtgatcc caattcattg acaaaggtta gcagtccttc
     1861 taagttgtta atgatttttt ggcgattttt ttcaaaccca tcaaacaggc ctattttgat
     1921 aaggggctct aagaagctgg ttttctggta tttttcagga atgctgcaca aaaagctttc
     1981 aacactggta aagggcctat tttcaatgat ccaatacgaa aattctctag gaagaccctt
     2041 gatgtttttt aagcccatat aaatcttatg acgctcaatc ttatcattga agggaatggt
     2101 gtttatcgtc acctgcgcgg cctcaaagcc aaaatctaac gcatctgtga tgtaatcact
     2161 gctagaataa ttcatcatga catcaaaaaa tacctcagga tagtgcgctt taaaataggc
     2221 tagctgaaag gctagggcag cataagcaaa ggcatggctg cggttaaagc cgtagcctgc
     2281 aaatttttcc atacgtgcaa acaatagtct ggctgtctcc tcagagcgac ccaaggctct
     2341 agcaccagtc agaaaatcct cctgcattct ttgcatctca acgaggtttt tcttagacat
     2401 agcacgccgt agcaaatcgg cctttccaag tgtaaagcct gcataaactt gagcaatctg
     2461 cataacctgc tcctgataaa gcatgatacc ataggttggc tctaatatcg gagcaatcac
     2521 cggatctatt agatcaatgt tttcctgtcc ctgccggcgc ttaataaaat tctgcgtgta
     2581 atcacttgct cccggtctat ttaagctggt tgtcgcaaca atttcctcaa agctagtcgg
     2641 cttgatccgt tttaacaggc taatcgcacc atgctgttca aattgaaaaa tgcccttggt
     2701 atcaccccta gcaaacaagg ctatcgtttc aggatcctct aggttaatag cttcaatgtc
     2761 aattgaaaga ccgtaatcgt tgaccacctt ttcctgcatt ttctgtacaa gcgtcaaatt
     2821 tctcagacca agaaaatcca ttttcagcaa gccattagct tcaacagcac tggcatcata
     2881 ctgagtcacc atcatatcct cccccttttt taagggaata tggttggtca gatggtcatc
     2941 actcatcacg ataccagcag cgtgaataga ggtctgtctt ggattgcctt caatgcgctt
     3001 agctatctca aatgcctttt gaaactctaa gcggctatta atggtctgtc tgaaggctat
     3061 atttttctca taaacagtgc tcagggtatc cttgaaccca atttttttag ttaggcttgt
     3121 tagctcgtat tctgggacac caaagcgttt gaacacatca cgaacagcct gcttaggacc
     3181 aaaagtcgaa aaggtaacaa tctgagctga gtgctcacta ccataccggt ctcgaacata
     3241 atgaagaaac tctgagcggt aaatatcagg caaatcaata tcaatatcag gcatgctgta
     3301 gcgttcttta ttcaaaaagc gttcaaacaa taaattgttt ttgacaggat caatcccagt
     3361 aatgcgcaac gaataagcca ctagactgcc tgctgctgaa ccacgcccca tgcccatata
     3421 atagcctcta ctccttccaa agcgcagcaa atcccagaca atgagaaaat aatcatcaaa
     3481 ccccatatct gaaataatag ccagctcctc tgccagacga aattggtaag gctccttcca
     3541 taattgcttt tctcttagac cagactcggt caattctctt agctcttctt ttgctggctt
     3601 atcgcggtta aatctcggaa gctttaaatc agtatcaaaa tgataagcaa tcgaagctgt
     3661 tagatttacg agattcacca aagcctcagg gcacttttcc tggaaaatag ccgtcatctc
     3721 ctgacaaggc gctaaaaact gatccttggc tactagagcc gtatctgcta agctaatatt
     3781 atcacgaatg gcatgcagca tttgcagagt ctcagtctca gcattatcaa aataacgtac
     3841 cgttctaagc ggaatcagtc tttctgtaga gtctatcttt gacaagtcgc ttgcctcatc
     3901 aatgccaatg aagtaatcaa aaggaagccc taaatcacgc aagctctgac taaaaggaac
     3961 gataactgct atcccttcta aatactgcac caatgtgtct aggtctaggt ctccagacat
     4021 tttttcagtc gaaagcttta agagctgctg atagcctgta tcatttttcg caacaagctt
     4081 cagcgtaaga gcctgctctt taactgtaat agccacctca agacctaaaa tcggctgaag
     4141 cccatgcctt tgacagccct taataaaatg atatgcccca tatagattat cctgatccat
     4201 aatccctatg gcttgatagc ctaatcgttt ggcttgttta aaataatggt ctaaatcaat
     4261 caaactatcc ataaaggaat aaactgtttt tgtatctaac tgagcaaaca tggacatctc
     4321 ctttagcgtt cttactacca ttatactatg aaaaagactt tactgcccag attttaagct
     4381 tttaatagca gtgatctgtc tttactgcac cactatcagc aggaatccca ctagcattgc
     4441 aagccagtat gtaactagag atgacacaca aggcttgaca agtcaatcgt ttttttgtat
     4501 catttaatta gtacaaatat taatcgcaga ttttagaaag aaaggagaca gtatgtcttg
     4561 gaaatttgat gagaaatctc ctatttacgc acagatagca cagcatatca tgctgcaaat
     4621 tgtcagccaa gagatcaaaa gtggagatca gctgccgact gtccgagaat atgctgaaat
     4681 tgccggcgtt aatcccaaca ccatgcaaag agcacttacc gaattagatc gtgaaggcat
     4741 agtttactcg caacgaactg ccggccggtt tgtaacagat aaccaagagc ttatcgcgcg
     4801 caaaagacga gagctggcca tcaacgagct caagtccttt attagcaata tgatcaaaat
     4861 aggttttgaa cgttcagaaa tcattcctgt tttaagtacc tttttagagg agggatcaaa
     4921 ctaatggcac aactattaca gctgcaccac gtctcaaaat cttacaaaaa acaattagct
     4981 attgatgatt taaccataac aatcccttct ggaaaaatta tcggcttact aggaccaaat
     5041 ggtagcggca aaactacact aattaagcta atcaacggac ttttacagcc agacaaggga
     5101 gacattgtta ttgacggctt tagaccatct gtagaaacta aaaaaatcat ttcttactta
     5161 ccagatacga cctatcttaa tgaaagtatg aaaatcaagg atatgctaga cttttttggt
     5221 gatttctatg ccgattttga cagagataaa gcgaccagtc tcctgaagga tttagactta
     5281 gatgctgaag agcgctttaa aaacctatca aagggaaata aggaaaaggc acagcttatc
     5341 ctcgtgatga gccgcaaagc aaagctctat atccttgatg agcctatcgg aggggttgac
     5401 ccggcagcaa gagattatat tcttaaaacc attattaata attactctga gcaagcctct
     5461 gttatcattt ctactcacct catctcagac attgagcctg tacttgatga agctattttc
     5521 ttaaaaaatg gtaagctctg cctttctgga aacgctgatg atttacgagt tcagcatcag
     5581 caatcgattg attcattatt tagagagatc tacaaggttt aggaggtagg catgtttgga
     5641 aaattattaa aatacgaatt tagatcaatt ggcaagtggt attttgcgct taatgccggt
     5701 gtcattgcta tcgcgatagt cctttctttt accatcaata cgcttacaaa caatcctgac
     5761 gaggttggtt taacaacaag tctggcaaac aaaatggttc ctctcacact ctcattaacg
     5821 tttggttctc tgattgccgg atcattctta tcaacgctat taatcatcat taatcgcttt
     5881 aacaaaaatg tctttgggcg cgagggatac ttaacactga cactaccagt aacagcacat
     5941 cagattatct tgtccaagct gttagcgtcc tttgtttgca gtatttttaa tggcattaac
     6001 ctattaatcg gtatctttat tttaatagcg ccaacagttg actttaccta tctactaaag
     6061 gtgctaaaga caattatgaa gccagaaaac ttagtcgaaa atgcttctat cctcatctac
     6121 atgcttttgt caaccataac aagtatacta ttgatttatc tagcaatctc aattggtcag
     6181 ctattttcaa atcgtcgtgg tttgatggca ttttgtgcct atttcatttt agttattatc
     6241 attattgtcg tcatgactta tttaaatgat gcgtttttca ccgtcaaccc aaatagctca
     6301 gactcgctac tctatttcgg tgatcataca gccatatcta ttttaaacat agagcaacta
     6361 gttgaaggca ttatccttta cgttgctact cacttcatca tcaaaaacaa gcttaatatc
     6421 caatgataac aaaaagtcta gccactgctt atcaggcaat gcctagactt ttttaatgga
     6481 aaaaccatag gatcaaatcc tttccaaaga taaaaagata gctgtagcca ataattgata
     6541 gtggcttcgt gattaaaata atggtcacaa aacgcttcaa cgacatctct gtcagcccag
     6601 taatcatgac cataatatct gctggtgaaa tcggagaaag catacagaga ataaacaatc
     6661 tctcataata tggcatctct aattttctct catacttgta aaaggtctgt tcctctataa
     6721 acagtaaaat aaagcgccta ccataggtct tcacaagtaa aaacagaatc acactaccaa
     6781 tgaagatacc aacatagtta taaagaaaac ccagcaaagg gccaaaaatc aaaaagcctg
     6841 caatagttgt cataccacct ggaataatag gaaaaacaat ctgaacaatt tgcacaccga
     6901 caaaaacaag ggggccaaaa accttgtgac tatgaacaag atccttgagt gcattgctgt
     6961 catttaaaat gccaagcctg taaaaccaaa aggctagcaa aaaagatccg actaaagcca
     7021 gacttcctaa tagcttaatc actttttgcc atatcacata aggcttcaac tcattatttc
     7081 tcatagcttc atcataccat aagcgctatt tttttgccat tttaaaaaaa ttttgctata
     7141 ctagcatccg taagtatctc atacgccttt ttatggggtt gttacggatt cgacaggcat
     7201 tatgaggcct attttgcaac tcatcggcag atgtaaaaat gccagttaaa tataactgca
     7261 aaaaataaca caacttacgc tttagctgcc taaaaaccag ccggcgtgac ttctatagga
     7321 ttgcttgtgt cttattagag gtctcaaaac agcaagctac gtttaggtga ttgtctagtc
     7381 acctaaaaag agaaccctag actcgcaggc tgatggcttg agttatgtgt ccttggtctg
     7441 ttaaagtaag acataaccta tggttgtaga caaataggtt agcaggtgtt tggacgtggg
     7501 ttcgactccc accagctcca tcaatactta ccgtaagtta ccataactta ctaaaacctt
     7561 gttaaatcaa ggttttttct ttttgtcctg ttcgtgggtt accgtaagtt tctatgaaag
     7621 tgatagcaaa aaaaaggcca aaaaatcctt taagaacagc ttgaattttc tctttagcta
     7681 atcttatatt tattttttta taatacttct tctacttgct tcattgacag cacattatca
     7741 aattttttcg gataattgcc ctgtattgcc tgttatatag acatcattta ctgctgcttt
     7801 a
//
LOCUS       DARYYD010000078         7495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.079, whole genome shotgun sequence.
ACCESSION   DARYYD010000078 DARYYD010000000
VERSION     DARYYD010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.079"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            436..975
                     /locus_tag="TV188_001787"
     CDS             436..975
                     /locus_tag="TV188_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535112.1"
                     /translation="MRQLIAAMVEKNQDLPRNILVAEMSLEKAVQPDDYRVKDYRNLR
                     QIRLTTSGLVLEVRLLKGLPARWLKKDTSAKPSKAVNSRALAEHSHVLSVNQAALQQF
                     LAETGDQNPLHQTAPYILPGALLMEEVSSWLTLDYRRLSLRFYAPAVVNAPIHLVMRE
                     KAISLYQAGELVAKGELHV"
     gene            972..2087
                     /locus_tag="TV188_001788"
     CDS             972..2087
                     /locus_tag="TV188_001788"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="HEL1535113.1"
                     /translation="MIDVYIQRGLRTPIGLAGKQFARVRPELLGAQLINALVKADKLA
                     IDEVICGNAVGTGGNIGRLMTLYSDLGETVPAITVDMQCASAGAALTMGYAKIKAGLA
                     TSLLAGGIESSSLQPQRIYAAADSRSGAYQVAQFSPDTSSQLAMIAGAERVAQAYQMT
                     PSQLNQWTLTSHQRAHIARQKHWLADIILAMPGMSDQGIRPRLSEKVLSKVPPILDKA
                     GLISAANTCLTHDAAAFLVLSNQRSAYQILDLVEVAGNPKTSPQMVVEASQVLLARNG
                     LAMTDMDAIEWNEAFAVIDLLFEHYFVEALDRYNIFGGALAYGHPFGASAAIIILHLM
                     QALALKQGKYGLAAIPAAGGQAFALLLEYHKDYSHAI"
     gene            2077..3339
                     /locus_tag="TV188_001789"
     CDS             2077..3339
                     /locus_tag="TV188_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1535114.1"
                     /translation="MLSRLLAWASQAPQRPAILTDQKTLTYQDLVEQILAYQPQESIS
                     YPTLIVKRDCFQQLIAFCYHLQHGNYPLICHPNLPEQEQRRLSSCDPPSDKAAFAVLS
                     SGSTGRPKVFWRSWASWSNFFEQQNQLFYFSEQTRLFSHGSLSFTGNLNLALAQLWAG
                     GCLVFSDQRSFKGWSSVWRRQKVTHLYLLPSLLQRLLPYFSADSYFAPYLLTSSQHLS
                     PELIRSYYQRFPRLELLMFYGASELSFISWCQGFEAMAIAGFVGRPFPQVKLELREGH
                     IFVQTPYAIEGIEQPYSVDDVGEMTAAGLILKGRTKDWVNQQGVKCHLPSLVQLVHQS
                     GVVQEAAAIKGGSSAADEHVILCLVLKKQGSLTAVKAYLEAHLSPAQRPKRYILLKEL
                     PLNDSGKLDSRRLSQLAHKSTKAAHNTK"
     gene            3385..4404
                     /locus_tag="TV188_001790"
     CDS             3385..4404
                     /locus_tag="TV188_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3114 domain-containing protein"
                     /protein_id="HEL1535115.1"
                     /translation="MVKKGGQLMKQDMLARYQALKPYVRAGLSSTSQQLLAAASAIDA
                     RLGSPTFLAIWQCEKQCRSPKELLGLVLDLVGMPIELSGRLEDTQALLSRFYPDLPPD
                     HCFWVELAQMVSLAFPDKELAQQSALAKGLHQLRYLISSQQAQYIRSHFRSEDMTDAQ
                     ALAIFLKDKKGPAFWRSQPDYTLMESARLHNKLKLVNGLASFPDHEISHNIKILLHFH
                     TEFILDSQGCFLNEIDGEVVTNKGIINGASFNYGTAGKRHWELDVAPISRHDPTFRKK
                     CLVGHQAPKWLKRSWLQLSPLDFDYSYFNAKGFFSLNSKSCFALVKRQARAFRWQIWR
                     SRFFK"
     gene            4603..5313
                     /locus_tag="TV188_001791"
     CDS             4603..5313
                     /locus_tag="TV188_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019321978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1535116.1"
                     /translation="MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEE
                     KPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSAKDSEFDKVIGLEIGADDYVTKP
                     FSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
                     LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSR
                     PEYILTRRGVGYYMKAYD"
     gene            5306..6658
                     /gene="vicK"
                     /locus_tag="TV188_001792"
     CDS             5306..6658
                     /gene="vicK"
                     /locus_tag="TV188_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEL1535117.1"
                     /translation="MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLM
                     SHKIRDLINGRYTDTINEKADIELMELSEQLNDLSDVFRLTHENLAQEKNRLASILAY
                     MTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
                     VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALKEDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVT
                     QLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITSIWLEIDNDKMTQVI
                     ENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKAR
                     SRAQGGAGLGLAIAKEIIKQRRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID
                     "
     gene            6662..7471
                     /locus_tag="TV188_001793"
     CDS             6662..7471
                     /locus_tag="TV188_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEL1535118.1"
                     /translation="MSEVGFKYSILASGSTGNCFYLETPKKRLLIDAGLTGKKITSLL
                     AEIDRRPEDLDAILITHEHSDHIKGVGIMARKYNLDVYANEKTWQMIDERHMIGNLDV
                     AQKHVFERGKTMTFGDIDIESFGVSHDAVDPQFYRIMKDNKSFVMLTDTGYVSDRLAG
                     IIENADGYLIESNHDVEILRAGSYPWSLKQRILSDLGHLSNEDGAGAMIRSLGNKTKK
                     IYLGHLSQENNIKELAHMTMVNQLAMADLGVGTDFTVHDTSPDTACPLTDI"
BASE COUNT         2020 a         1599 c         1798 g         2078 t
ORIGIN      
        1 cctcggcacg atagtcctga acccttgttt cagcctactt cttcactgtc ctaagatcgc
       61 ttttaggatg gccttgccaa gtctaggcct tagttggagt accgtaacat tcgcagcagc
      121 ctttatcagc taatgtctta gaatgataat aggtcatgcg acttatctag cgcgtgaatg
      181 accttgaagc ttgccttgtg tgctttcttc tgtctatttc aagtagagct gaatgactat
      241 cagttacctg taggcagagg ctgtagcagc cttgatttat taaatgatat tgaacatgat
      301 gtgatcagac aaaaaaggtt aggctaaagg ctcgcctttt tttgctaact aagccttgtt
      361 tttgctgttt tttcttttct tgtgttcagg tattcagtat aataaagtta acttgttcgc
      421 aaaaggatgg ttacaatgag acagctaatc gcagctatgg ttgagaaaaa tcaggattta
      481 ccaagaaaca tccttgtggc tgagatgagc ttggaaaaag ctgtgcagcc agatgattat
      541 cgcgtaaagg attatcgaaa tctgcggcag atcagattga ctacatcagg gcttgtgcta
      601 gaggttcgat tactaaaagg gctaccagcc aggtggctga aaaaggacac aagtgctaag
      661 ccttctaaag cagttaatag ccgagcatta gctgagcata gccatgtact gagcgttaat
      721 caggcggcct tacagcaatt tctagcagaa acaggagatc aaaatcctct tcatcaaaca
      781 gctccctata tcttaccggg agccctcttg atggaagagg ttagcagctg gcttacttta
      841 gattaccgta ggctaagcct gcgtttttat gccccagcgg ttgtgaatgc tcctattcac
      901 ctagtgatga gagaaaaagc tatcagcctc tatcaggcag gagaattagt cgcaaaagga
      961 gagcttcacg tatgattgat gtctacattc aaagagggct tagaacgcct attggtctag
     1021 ctggcaagca atttgctagg gtgcgtccag aactgcttgg tgctcagctg attaatgcct
     1081 tagtcaaagc agataagctg gctattgatg aggtgatctg cggtaatgct gttgggacag
     1141 gcggtaatat tggccggctg atgactctgt attctgactt gggagagacc gtacctgcca
     1201 taaccgttga catgcaatgt gcctcggctg gtgcagctct tactatgggc tatgctaaaa
     1261 tcaaggcagg tcttgccact agcttgttag caggagggat cgaaagcagc tctttgcagc
     1321 ctcagcgtat ctatgctgct gctgatagcc gatcaggtgc ttatcaggta gctcagtttt
     1381 caccagatac cagtagccag ctggctatga tagcaggagc agagcgggtg gctcaggcct
     1441 accaaatgac cccctcacag ctcaaccagt ggacccttac tagccaccag cgagcacaca
     1501 tagctaggca gaagcattgg ttagctgata ttatattagc aatgccagga atgtctgatc
     1561 aaggcattcg ccctcgcctg tcagaaaagg tcttgagcaa ggtgccgccg atacttgata
     1621 aggctggcct catcagtgct gctaatacct gcttgaccca tgacgcagca gcatttttag
     1681 tgctaagcaa tcaaagatca gcctatcaaa tccttgatct tgttgaggtt gctggcaatc
     1741 ctaaaaccag tcctcaaatg gtggttgagg ccagtcaggt cttattagct agaaacggcc
     1801 tagccatgac ggatatggat gcgatcgagt ggaatgaagc ttttgcagtg attgatctgc
     1861 tttttgagca ttattttgtg gaggcccttg atcgctacaa tatttttgga ggcgctcttg
     1921 cctacggtca tccctttggc gcgtcagcag ccattatcat tttgcatcta atgcaggctt
     1981 tggccttaaa gcaaggaaag tatggtttag cagccattcc agcagctggt ggtcaagcct
     2041 ttgccctgtt attggaatat cataaggact actcacatgc tatctagact gctagcttgg
     2101 gcaagccaag caccacaaag acctgctatc ctaacagacc aaaaaaccct aacctatcag
     2161 gatcttgtag agcagatctt ggcttatcag cctcaggagt ctatctccta tccgaccctg
     2221 attgtcaaaa gggattgctt ccagcagctg attgcttttt gctatcattt gcaacatgga
     2281 aactacccac ttatctgtca cccaaatcta ccagaacaag agcaaaggcg tctgtctagc
     2341 tgcgatcctc catcagacaa ggcggctttt gcggtgctta gctctggctc tactggccgt
     2401 cccaaggttt tttggcgctc ctgggcttct tggtctaatt tttttgagca gcaaaaccag
     2461 ctgttttatt tctcggagca aacaaggcta tttagccatg gaagcttgag ctttacaggc
     2521 aatttgaact tagctctggc gcagctctgg gccggaggct gtctggtctt tagtgatcag
     2581 cggtccttta agggctggtc ctctgtttgg cgcaggcaaa aggttactca tttatatctc
     2641 ttaccgagtc tgctacagcg gctactgcct tacttttctg ctgatagcta ttttgccccg
     2701 tatttattaa cctcatctca gcacttgtca ccagagctga ttcgcagcta ttaccaacgc
     2761 tttccgcggc ttgagttgtt gatgttttac ggtgccagtg agctttcctt tatcagctgg
     2821 tgtcagggct ttgaggctat ggcaatagct ggctttgtag ggcgtccctt tcctcaggta
     2881 aagctggagc tccgagaggg gcacattttt gttcagactc cctatgccat tgagggcatt
     2941 gagcagccct atagtgtcga tgatgtgggg gaaatgacag cagcaggctt gattctaaag
     3001 gggcgaacca aggactgggt gaatcagcaa ggtgtcaaat gccatcttcc tagccttgtt
     3061 cagctagtcc accagtcagg agttgttcaa gaagcagcag cgataaaggg tggcagcagt
     3121 gcagctgatg agcatgtgat cctgtgcttg gtgttgaaaa agcagggaag ccttaccgct
     3181 gttaaggcct atcttgaggc gcacctaagc ccagctcaga ggcctaaacg gtatatactc
     3241 ttaaaggagc taccacttaa tgacagtgga aagcttgata gcagaaggct tagccagctc
     3301 gcccacaaat caactaaagc tgctcataac accaaataag gaaaagtcac ctgagcccaa
     3361 agcatcagct caatatggta taatatggtc aaaaaaggag gtcagttgat gaagcaggat
     3421 atgttagcac gttatcaggc actcaagcct tacgtaagag caggtctttc ctcgacctct
     3481 cagcagctat tggcagctgc ctcagctatt gatgctcgct taggctcacc gaccttttta
     3541 gccatttggc agtgtgaaaa acagtgtcga tctcccaagg aattactagg gcttgttcta
     3601 gatcttgtcg gcatgccaat agagttatcc ggaaggctag aggatacgca ggctctgctg
     3661 agtcgctttt atcctgactt gccaccggat cattgctttt gggtggagct agcccagatg
     3721 gttagtcttg cttttccgga taaggagcta gcgcagcaga gcgcgttagc taagggtctt
     3781 catcagcttc gctatctcat ttcgagccag caggcacaat atattcgcag ccattttaga
     3841 tcagaggaca tgactgacgc tcaggcactg gctatctttc tcaaggataa aaaaggccca
     3901 gctttttggc gcagccagcc tgactacacg cttatggaat cggctcgtct gcataacaag
     3961 ctaaagcttg tcaatggatt agcaagcttt cctgatcatg agatttccca taatattaaa
     4021 attctgttgc atttccatac cgaatttatc ctcgatagtc aggggtgttt tcttaatgaa
     4081 atagatggtg aagtggtgac caacaaggga atcattaacg gagcctcctt caattatggc
     4141 acagcaggca agaggcattg ggagctagat gttgctccta tcagccgaca tgacccgacc
     4201 tttaggaaaa aatgcttagt aggccaccaa gctcctaagt ggctgaagcg ctcttggctt
     4261 cagttatcgc cactagattt tgactattct tattttaatg ctaagggctt ttttagcctc
     4321 aatagcaaaa gctgctttgc cttggttaag cgacaggcac gtgcctttag atggcagatc
     4381 tggcgtagca gattttttaa gtaatggatc agtagctggc ttgcttgatg aggtatttag
     4441 agagcgtttt tgtggctagt atagtggtca ttgtcaattt ctcctaaatt ttgatataat
     4501 caaaaggaca taataaaatg atcggtctcg tctctaaatc cttatggaat agggattagg
     4561 cagcgtagca attaatgaag agaaatgttc tgaggtataa gcatgaagaa aatactgatt
     4621 gttgatgatg aaaagccgat ttctgatatc attaaattta atctgacaaa ggaaggctat
     4681 gatacggtca cagcatttga tggcaaagag gccgttgcag tctttgaaga ggaaaagcca
     4741 gatttgatta ttttggattt gatgcttcct gaattagatg gccttgaggt agccaaggaa
     4801 atccgcaaga ccagccatat tcctatcatc atgctatctg ctaaggatag cgaatttgat
     4861 aaggtgattg gacttgaaat aggggccgat gattatgtga ctaagccctt ttcaaatcgt
     4921 gagctgctgg cgcgtgtcaa ggcacatttg cgtcggacag agactattga gacagcagta
     4981 gccgaagaaa atgcctcctc aggctctcag gagctaacca tcggcaatct acagatttta
     5041 ccagatgcct ttatcgctaa aaagcatggt caagaggttg agctgaccca tcgtgagttt
     5101 gaattgctgc atcatctggc aaaccatatc ggacaggtca tgacacgtga gcatttgctt
     5161 gagaccgtat ggggctacga ttattttggc gatgttcgaa ccgttgacgt tactatccgt
     5221 cgcctgcgcg aaaaaataga ggatacaccg agtcgtccag agtatatttt gacaagacgt
     5281 ggtgttgggt actacatgaa ggcttatgac taaggacatc attggaaacc tttctgcatt
     5341 tgagctagcc atactcttat tgcttgtttt tgttgctttt tatttcattc atttagccat
     5401 tcgtgattat cgcaatgctc ggatcattcg tctgatgagc cataagataa gagatttgat
     5461 caatggtcgc tatactgata cgatcaatga aaaggctgat attgaattga tggagctgtc
     5521 tgagcagctc aacgacctat cagatgtttt tcgtctgacc catgaaaacc ttgcccaaga
     5581 gaaaaatcgt cttgctagta ttttggctta tatgacagat ggggtccttg cgaccaatcg
     5641 ttccggcaag attatcatga ttaatgagac tgctcaaaag cagctcaatt taaatcgtga
     5701 gcaggcgctg gaaaaaaaca ttacagattt attagacagt gactcacctt acacctaccg
     5761 agagctggtc tcaaaaacac cgattgtgac cttaaatcgt cgtaatgaca caggagagtt
     5821 tgtttcgctg cggctgcgtt ttgcgcttaa taggcgagag agcggcttta tttcaggtct
     5881 agttgttgtg cttcatgaca cgactgagca ggaaaaggag gagcgtgagc gcagactctt
     5941 tgtctcaaat gttagccatg agcttcgcac acctttgacc tctgtcaagt catacctaga
     6001 ggctctagat gagggcgcgc taaaggagga catagcccca agctttataa aggtctcact
     6061 agacgaaacc aatcgcatga tgcgcatgat ttcagatttg ctcaatctat caagaattga
     6121 taatcatgtg acacagctgt ctgttgaaat gaccaacttt acagccttta tgacctctat
     6181 cttaaaccgc tttgatttgg tgaaaaatca gcacaccagt acaggaaaat cctatgaaat
     6241 tgtcagagat taccctatca cctctatttg gctagaaatt gataacgata aaatgacgca
     6301 ggtcattgaa aatattttaa acaatgccat caaatattca cctgatggtg ggaaaattat
     6361 cgtaaacatg aaaacaacag atacccagct aatcatttcg atttctgatg agggattggg
     6421 cataccaaag aaggacctgc ctttgatttt tgaccgtttt taccgagtgg ataaggctag
     6481 aagtcgggcg cagggggggg ccggcttagg gctggctatt gctaaagaaa ttattaagca
     6541 gcgccgcggc tttatctggg ctaagagtga ctatggcaag gggtcaacct ttaccattgt
     6601 gttaccttac gaaaaggatg ctgctatcta tgatgaatgg gaggatgata ttgattaatt
     6661 gatgagtgag gttggcttta aatatagtat tttagcatca ggatcgacag gtaactgctt
     6721 ttacttggaa acgcccaaga agcgactgtt gattgatgca ggactgactg gaaagaaaat
     6781 caccagtctt cttgctgaga ttgacagaag gcctgaggat ttggatgcta tcttgattac
     6841 ccacgagcat tccgaccata tcaagggtgt tggaatcatg gctcgaaaat ataacctaga
     6901 tgtctatgcc aatgaaaaga cttggcagat gattgatgag cgtcatatga ttggcaacct
     6961 agacgtcgca caaaagcatg tctttgaaag aggtaagacc atgacctttg gagacattga
     7021 cattgagagc tttggtgtta gtcatgacgc tgtagaccca cagttttacc gcattatgaa
     7081 ggataacaag tcctttgtca tgctgacgga tacaggatat gtgagcgacc gcttggctgg
     7141 gatcattgaa aatgctgacg gctacttgat tgagtcaaat cacgatgtgg agatattgcg
     7201 agccggctct tatccttgga gcctcaagca gcgaatctta tctgacctag ggcatttatc
     7261 caatgaagat ggtgctggcg ctatgattcg aagcttgggc aataaaacaa agaaaatcta
     7321 cctcggtcac ctaagccagg agaacaatat caaagaatta gcacacatga caatggtcaa
     7381 tcagctagca atggcagatt taggtgttgg aacagatttt actgttcatg acacctcacc
     7441 agataccgcc tgtcccttga cagacatcta gccttatgac ttcacccctg cttgt
//
LOCUS       DARYYD010000079         7048 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.080, whole genome shotgun sequence.
ACCESSION   DARYYD010000079 DARYYD010000000
VERSION     DARYYD010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7048
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.080"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(231..611)
                     /locus_tag="TV188_001794"
     CDS             complement(231..611)
                     /locus_tag="TV188_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HEL1535119.1"
                     /translation="MIKVFETRVTAIGSEAADMISAANMLILFDQGAPADLADFCYTI
                     DNKQVSGSISAGGQLVIDQMAYDITAVGAVVEKNLAQLGHITISFDGSTASSLPGTLH
                     VKGKGLPQVRQGSLVQIFAWLRCS"
     gene            complement(645..1637)
                     /locus_tag="TV188_001795"
     CDS             complement(645..1637)
                     /locus_tag="TV188_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002284531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HEL1535120.1"
                     /translation="MTYHSITVVKGSGGYGGPLTITPTEAKHKFIYITGGGKKPDIVD
                     KIAALTGMEAVNGFVTSIPDDEIALAIVDCGGTLRCGIYPKKGIPTINIVATGKSGPL
                     AQYITEDIYVSAVGLEQITASDAQAHVASAKESSVPKASSYDTSKKITEQRAESSFVA
                     RIGMGAGKVVAIFNQAAREAIQTLINTILPFMAFVSLLIGFIQGSGVGNWLAKLMVPL
                     AGNIWGLIIIGFICSLPFLSPLLGPGAVISQIIGTLIGVEIGKGTIPPQMALPALFAI
                     NTQNGCDFIPVALGLSEANAETVEVGVPSVLYSRFLNGVPRVVVAWIASIGLYQ"
     gene            complement(1653..2198)
                     /gene="srlA"
                     /locus_tag="TV188_001796"
     CDS             complement(1653..2198)
                     /gene="srlA"
                     /locus_tag="TV188_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677306.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HEL1535121.1"
                     /translation="MEMITRFAEGFMKLFQLGGETFVSWMTGIVPVVLMLLVAMNALI
                     GILGDQRVNQLAKISAKNPISRYMVLPFISAFMLGNPMAISMGRFMPEYYKPSYVAAQ
                     MQFCHTSNGVFPHINPGELFVWLGIASGIKTLGLSQMDLAIRYLLVGLIMNFVGGWVT
                     DFTTAYVAKQQGVTLSKMIEL"
     gene            complement(2334..2795)
                     /locus_tag="TV188_001797"
     CDS             complement(2334..2795)
                     /locus_tag="TV188_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019323881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HEL1535122.1"
                     /translation="MSFMVIFGLFVIVAYLFQLLLGLRQLKHFNAVYASLRRQGRVAI
                     GRRAGKIRAGTIVMFALDQSGKVLDARQMQGVTVAARFKPMPAYIGQDIHYFDRYNPL
                     IRRENKLLRLAIEDAREVFLRVEAGVYEDAPKYASAFDWTLQAKQLLARFK"
     gene            complement(2795..4567)
                     /locus_tag="TV188_001798"
     CDS             complement(2795..4567)
                     /locus_tag="TV188_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HEL1535123.1"
                     /translation="MSNAASSIGQLNDILDGDATITQQGAFLQLQVYDYARLETILAG
                     SLRKASDFNSASKRVAYLLKRLLQSSSALVIDDLADEIGVSRSTINKDLKAAKALART
                     YSVMIQGKPNHGIQAVGTELNLRLLYVHEVYKYFEPQGLCGDSLFFLDELYQTYQLPR
                     KIQELLTKSFAITIERMRQGRYLTDPIPYYSNEVDSSAFMEELVYHIELAYQLSLSQY
                     ERQFISFPLNIQYIEDLAYQEKPLQQSIVRLYSKMIEHIKTSLLVTIDQDKLFVALHT
                     HLKLLVNRLIFHVQANDIFHGEIRYKYPLAFDMAIVAAQVLAEEFDCAIELSECSYLA
                     LYFEMMMKDAEHVTEPTVKKIAVVCTTGRGTANMICRRLSKVLGPDLLISQFSEEQFN
                     PDDNDHYFAIFTTVPLKFGQLKSPVLQITNLFDDQWLQNEWRRVHHYHQKNLATITLH
                     FARLSKGKAYTDYLTEMAELLEEKQLVDRQFGQRLLEREALQSTLFGNRIAFPHTIND
                     KETKTVLLLGLLDEPYREHDCLVEFIFLVAISKRVEAQMEADLLKIYDDIFKIASDDK
                     LQAELRSLKSQAEFIAFTKEKGVF"
     gene            complement(4861..6210)
                     /locus_tag="TV188_001799"
     CDS             complement(4861..6210)
                     /locus_tag="TV188_001799"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEL1535124.1"
                     /translation="MSHITFDYSKVLEQFAGQHEIDFLQGQVTEADQALRQGTGPGSD
                     FLGWLELPENYDKEEFARILKAAEKIKADSDVLVVIGIGGSYLGAKAAIDFLNSHFAN
                     LQTAKERKAPQILYAGNSISSSYLADLVDYVQDKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDKVKGAVKVEADANHWETFVVPDNVGGRFSVLTAVGLL
                     PIAASGADITALMEGANAARKDLSSDKISENIAYQYAVVRNILYRKGYVTEILANYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGYRNLFETVIRVDK
                     PRQNVIIPEMAEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGGVPNMFITLPEQDEF
                     TLGYTIYFFELAIALSGYLNGVNPFDQPGVEAYKKNMFALLGKPGFEELGAALNARL"
     gene            complement(6386..>7048)
                     /gene="glmU"
                     /locus_tag="TV188_001800"
     CDS             complement(6386..>7048)
                     /gene="glmU"
                     /locus_tag="TV188_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015016740.1"
                     /note="forms a homotrimer; catalyzes the acetylation of
                     glucosamine-1-phosphate and uridylation of
                     N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc;
                     function in cell wall synthesis; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEL1535125.1"
                     /translation="ERINRQHMLNGVTLQNPAATYIESSVEIAPDVLIEANVTLKGQT
                     RIGSRSVITNGSYILDSRLGEGVVVSQSVIEDSVLADGVTVGPYAHIRPDSQLDESVH
                     IGNFVEVKGSHLGANTKAGHLTYLGNAEIGSEVNIGAGSITVNYDGQRKYQTVIGDHA
                     FIGSHSTLIAPVEVGENALTAAGSTIAQSVPADSVAIGRSRQVVKEGYAKRLPHHPDQ
                     PQ"
BASE COUNT         2022 a         1735 c         1409 g         1882 t
ORIGIN      
        1 aaaggataaa ttaattaaat aatcaactaa tgtacaagtt gtctttaagc tgaaaagagg
       61 ctatcaacag cctctttttt tgatgatata gataagccca atgcttcctt agaagagctc
      121 ttctgtgaga tgaccttatc acctgacatt agctgcttgg ctcatgccta cagctaaagg
      181 aaatgccctg caaggatagc agcacttagc ctgctggtct acggcgtgtc tcagctgcac
      241 ctaagccaag caaagatttg tactaggctg ccctgcctga cctgtggcag ccctttgccc
      301 ttgacatgca gagtaccggg aagagagctg gctgtggagc catcaaaaga aatggttata
      361 tgccctagct gagcaagatt tttttcaaca acagcaccta ctgctgtgat gtcatatgcc
      421 atttgatcaa tgactagctg accaccagca gagatagacc cagacacttg cttgttgtca
      481 atcgtatagc aaaagtctgc caagtctgcc ggtgctccct gatcaaaaag aataagcata
      541 ttggcagcac taatcatgtc tgccgcctcc gatccaatag cggtaactct tgtttcaaat
      601 acttttatca tacattctct ctcttcctat catacgatag ctccttactg atacaaacca
      661 atacttgcaa tccaagcaac aacaacccga ggaacaccat ttaaaaagcg tgaataaagc
      721 acagatggca ccccaacctc tactgtctca gcattagcct ctgataaacc aagcgctact
      781 ggaatgaaat cacagccatt ttgcgtatta atagcaaaaa gtgcaggaag agccatttgt
      841 ggtggaatag tgccttttcc aatctcaaca ccaatgagcg ttccgatgat ttgactaata
      901 accgcaccag gtcctaacag cggtgataaa aatggcaacg aacagataaa gccaatgata
      961 atcaagcccc aaatattacc agccagcggt accatgagct tggctagcca attaccaaca
     1021 ccagagcctt ggataaaacc aattaaaaga gagacaaatg ccatgaatgg caaaatcgta
     1081 ttgattaagg tctggatagc ctcacgcgcc gcttggttga agatagcaac taccttacct
     1141 gctcccatac caatgcgggc aacaaagctg ctttctgcgc gctgctcagt aatctttttg
     1201 ctagtatcat agctgctagc ctttggaact gatgactcct tagcactagc aacatgagcc
     1261 tgagcgtcac tggctgtgat ttgctcaaga cctacagcag acacgtaaat gtcctcggta
     1321 atgtactgtg ccaagggacc gcttttacct gtcgccacga tattaatggt tggaatgcct
     1381 tttttagggt aaataccgca gcgtagggtg ccgccacaat ccacaatagc tagggctatc
     1441 tcatcatcag ggattgaggt cacaaagcca ttgaccgcct ccatacctgt tagggcagca
     1501 attttatcga caatgtcagg cttttttcca ccgccagtaa tatagataaa tttgtgctta
     1561 gcttctgttg gtgtaatggt tagcggccca ccatagccac cgctcccctt aacaactgta
     1621 atactgtgat aagtcatcat gctacctctc ttctataatt caatcatctt acttaatgtc
     1681 acaccctgct gcttggccac gtaggctgtc gtaaagtcag ttacccagcc accaacaaag
     1741 ttcatgatta acccaaccaa gaggtaacga atcgccaagt ccatttggct caagcctagc
     1801 gtcttgatac ctgaggcaat acctaaccag acaaacaatt ctcccggatt aatgtgtgga
     1861 aagacaccgt ttgacgtatg acaaaattgc atttgagcgg caacatagct tggcttgtaa
     1921 tactcgggca taaagcgtcc catgctgatt gccatcggat tacccagcat aaaagctgaa
     1981 ataaaaggca ataccatgta gcgactgata gggtttttag cagagatttt tgccaattga
     2041 ttgacccttt gatctcctaa aataccaatt aaggcattca ttgcaaccag cagcatcaag
     2101 accaccggca caatgccagt catccagctg acaaaggttt caccaccaag ctggaagagc
     2161 ttcataaagc cttccgcaaa tcttgttatc atttccataa ataaactcct catatgatgt
     2221 acttacaagc aagacaatac aaatgtactg cctgcttgat aatagctgct tgagctggac
     2281 tcaaaacagc ttttatgttg acaaggcaag caatcaatcc tgcttttggc accttacttg
     2341 aagcgtgcca gcagctgctt ggcctgtagg gtccaatcaa aggctgaggc atattttggt
     2401 gcgtcctcat agacccctgc ctcaaccctc aagaagacct ctcttgcgtc ctcaatagcc
     2461 aagcgcagca atttattttc tcgtctaatc aagggattgt agcgatcaaa ataatgaata
     2521 tcctgaccga tataagctgg cattggctta aacctggctg ccactgtcac accctgcatt
     2581 tgcctagcat ctaatacctt acctgactga tccaaggcaa acatgacaat ggttccggcc
     2641 ctgattttcc cggctctacg gccaatagca acgcgcccct gtcgtctaag actggcataa
     2701 acagcattga agtgcttaag ctgtctcaga cctagcaata attgaaaaag gtaagcaact
     2761 atgacaaata gtccaaaaat aaccataaaa ctcattaaaa aactcctttt tccttggtaa
     2821 atgcaataaa ctcagcttga ctttttaggc tccttagctc cgcctgaagc ttatcatcgc
     2881 ttgctatttt gaaaatatca tcataaattt tcaagagatc agcctccatc tgcgcttcaa
     2941 ccctcttgga aatagccact agaaaaataa actccaccag acagtcatgc tcacgataag
     3001 gctcgtctaa tagacccagc agcaggacag tctttgtttc cttgtcatta atcgtatgtg
     3061 gaaaggcaat gcgattgcca aataaggttg attgcagggc ctcacgctct agcaggcgtt
     3121 gaccaaactg cctgtcaacc agctgctttt cctcaagcag ctccgccatt tcagtcaggt
     3181 agtcagtgta ggccttcccc tttgacagac gagcaaagtg tagggtgatg gtcgccaggt
     3241 ttttctggtg ataatgatgt accctgcgcc attcattttg cagccactgg tcatcaaaca
     3301 gatttgtgat ttggagaaca ggagatttta gctgaccaaa cttcagcggc acagtggtga
     3361 atatggcaaa atagtgatca ttgtcatcag gattgaattg ctcctcagag aattgtgaga
     3421 tcaacaaatc aggacctagc accttgctca agcgacgaca aatcatattg gcagtgccac
     3481 gacctgtcgt gcagacaacg gcaatttttt tcactgttgg ctctgtcaca tgctcagcgt
     3541 ctttcatcat catttcgaaa taaagggcca aatagctaca ctcagacaat tctatggcgc
     3601 agtcaaactc ctctgctaag acctgagctg cgacaatggc catatcaaag gccaaggggt
     3661 atttgtatct aatttctcca tgaaaaatat cattggcctg aacatgaaaa atcaaacgat
     3721 tcaccaagag cttcaaatgc gtatgcaaag caacaaaaag cttgtcttgg tcaatagtca
     3781 ccaagagact ggtcttgatg tgctcaatca tttttgaata aagcctgaca atgctctgtt
     3841 gcagaggctt ttcttgatag gctagatcct cgatgtattg gatattcaag ggaaagctaa
     3901 taaactggcg ctcgtattga ctcagtgaca gctgataggc tagctcaatg tgatagacca
     3961 gctcctccat aaaggcactg gaatcaacct cattgctata gtaaggaata ggatctgtca
     4021 gatacctgcc ctgacgcatt cgctcaatgg ttatcgcaaa gctcttggtc aaaagctctt
     4081 ggattttgcg aggaagctgg taggtctgat acagctcatc tagaaaaaac aagctatcac
     4141 cacacaagcc ctgcggctca aagtatttgt aaacctcatg aacataaagc agccgaaggt
     4201 tcaactcagt gccaacagcc tgtatgccat gattgggctt gccctgaatc atgaccgaat
     4261 aggtcctagc aagagccttg gctgccttta ggtctttatt gatcgtgctg cgactgacgc
     4321 caatctcatc agccaaatca tcaatgacta aagctgagga gctttgcagt agccttttta
     4381 gaagataagc tacccgcttg ctagcggaat taaagtcact agccttacgt aaactaccag
     4441 ctaatatcgt ctctaatcta gcataatcat agacctgcag ctgcaaaaag gcgccttgtt
     4501 gggtgatggt cgcatctcca tctaaaatgt cattgagctg accaatgcta cttgcagcgt
     4561 ttgacatcgt cttttcacaa agtcacagct tagaaagcta gcagaggaga caaaagcaag
     4621 accttatcag ctaacagcag catattaaac gaacagctag tgatactgat cctactaagc
     4681 atagagctcc aaaagcctgg cttaaatagt attcaaaata gaacaagagc tctcaagaac
     4741 aataacctag cgcactactt gccttgataa gcctaaccga ccttgaaaag aagcaaaaaa
     4801 aagagcctct cacgagactc tttgttatgt tttagcagac tagtctagct agctctgtca
     4861 ttacaagcgt gcgttgagcg ctgctcctag ctcttcaaag cctggcttac caagaagggc
     4921 aaacatgttt ttcttgtaag cctcaacacc tggctgatca aatggattta ccccattgag
     4981 gtagcctgaa agggcaatag caagctcaaa gaagtagatc gtatagccta gtgtaaattc
     5041 gtcttgctct ggaagcgtga taaacatatt tggcacacca ccgtctgtat gggcaagaag
     5101 gacaccatct gttgcttttt tgttgacaaa gtcaacgtct ttgccttgta ggtagccaag
     5161 gccatcaaga tcctcagcca tttctgggat aatcacattt tgacgtggct tatccacacg
     5221 aatcactgtc tcaaagaggt tacggtagcc ttcttggata aattgaccaa gagaatgcag
     5281 gtctgtcgag aaattagctg aagttgggta aatacccttt tggtcctttc cttcagactc
     5341 accagccagt tgcttccacc attcgctaaa atactgcaat gatggctcat agtttgccaa
     5401 aatttcagtt acatagcctt tgcgatagag gatattgcga actacagcat attggtaagc
     5461 gatgttttct gagattttat ctgatgacag gtccttacga gctgcatttg ccccctccat
     5521 cagcgcggta atatcagcac ccgatgctgc aattggcaac aagcccacag ctgtcagcac
     5581 tgaaaaacga ccaccaacat tatctggcac aacaaaggtt tcccaatgat ttgcatcagc
     5641 ctcaacctta acagcaccct tgaccttatc agtcgttgca tagatacgct tgttggcctc
     5701 ttcttgaccg tactttttaa caagtaattc tttaaagaca cgaaaggcga ttgcaggctc
     5761 tgttgttgta ccagacttag aaatcacgtt aacagagaaa tctttatctt gaacatagtc
     5821 cacaagatca gcaagatagc ttgatgagat ggagttccca gcataaagaa tttgtggtgc
     5881 tttgcgctct tttgctgttt gtaggttggc aaaatggctg ttcaaaaagt caatcgcagc
     5941 cttagcacca aggtaagagc caccaatacc aatcacaaca agaacgtcac tgtcagcctt
     6001 aatcttctca gctgctttaa ggatacgagc aaattcttct ttgtcatagt tttcaggtaa
     6061 ctcaagccag cccaagaaat ctgatccagg tccagtgccc tgacgtagtg cctgatcagc
     6121 ctctgttacc tgaccttgta aaaagtcaat ttcatgctgt ccggcaaatt gctcaagaac
     6181 ctttgaataa tcaaatgtaa tatgtgacat tattttactc ccttaacttt taaagtttca
     6241 ttagtatcat aaccttttct attcaatatt tcaatgtttt ttatttttgg ggagggtggc
     6301 ctgactttaa cgacatgagg atcatttctg tctaaaagca gctttgtgat gagcctagcg
     6361 cttccctatc tgcttctact atagcttact ggggctgatc cgggtgatgt ggtagcctct
     6421 tggcatagcc ttccttcacc acctgacggc tgcgccctat agccacactg tctgccggca
     6481 ctgactgggc tatcgtagac cctgcggctg ttaaagcatt ctccccaacc tctactggag
     6541 ctatcaaagt cgaatgactc ccaataaaag cgtgatcgcc aatcactgtc tggtatttcc
     6601 gttgaccatc ataattaacc gtaatgcttc ctgcaccaat attaacctct gagccaatct
     6661 cggcattccc caggtaagtc aaatgccctg ccttggtatt ggcccctaga tgagacccct
     6721 taacctctac aaagttccca atatgaacgc tctcatcgag ctgggagtct gggcgaatgt
     6781 gcgcataggg ccctactgtc acaccatctg ctaggactga atcctcaatc actgactggc
     6841 tcaccactac gccctcacca agcctcgaat caaggatata gctcccattg gttataacac
     6901 ttctgctgcc aattctagtc tgtcccttta aggtcacatt agcttcaatc aagacgtccg
     6961 gcgcaatctc tacactactt tcaatatagg tagctgctgg attttgcagg gtcaccccat
     7021 taagcatgtg ctgcctattg atccgctc
//
LOCUS       DARYYD010000080         6885 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.081, whole genome shotgun sequence.
ACCESSION   DARYYD010000080 DARYYD010000000
VERSION     DARYYD010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6885
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.081"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(25..486)
                     /locus_tag="TV188_001801"
     CDS             complement(25..486)
                     /locus_tag="TV188_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComE"
                     /protein_id="HEL1535126.1"
                     /translation="MTDRLSWQDYFMANAELISKRSTCDRAFVGAVLVKDNRIIATGY
                     NGGVSATDNCNEAGHYMEEGHCIRTVHAEMNALIQCAKEGISTAGTEIYVTHFPCINC
                     TKALLQAGICKITYKSHYRPHPFAIELMDKKGVAYVQHDVPQIILGGAVEP"
     gene            complement(530..1606)
                     /locus_tag="TV188_001802"
     CDS             complement(530..1606)
                     /locus_tag="TV188_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEL1535127.1"
                     /translation="MSSFLAQRLSNCQALLEKKGLEAILITNLTNIYYLTGFSGTSAT
                     VFISPKRRVFITDSRYTLIAKASIEGFDIIESRTPLAEIAAILQADKLSSLAFEDQVS
                     FSFSQSLQAAFSEVTLLPQSGFIEALRLIKDASEIDIIAKACSISDKAFCDVLDFIKP
                     GQTSELEVANFLDFRMRQYGASGISFDTIAASGYRSAMPHGRATDKIIQQGETLTLDF
                     GCYYQHYVSDMTRTIHIGQVTDQEREIYELVLAANQALIAKAGAGMTYREFDAIPRQL
                     ITEAGYGSHFTHGIGHGIGLDIHEDPFFAKTDQRLLAGMVVTDEPGIYLDGKYGVRIE
                     DDLVITETGCQVLTKAPKELIVLT"
     gene            complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TV188_001803"
     CDS             complement(1897..4719)
                     /gene="uvrA"
                     /locus_tag="TV188_001803"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEL1535128.1"
                     /translation="MQDKLIIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGLSPAISIDQKTTSKNPRSTVGTV
                     TEINDYLRLLYARVGTPYCINGHGAITASSVEQIVEQVLELPERTRMQILAPLVRRKK
                     GQHKTVFEKIQKDGYVRVRVDGEIFDVSEVPALSKSKMHNIEVVIDRLVNKDGIRSRL
                     FDSIEAALRLGDGYLMIDTMDGNELLFSEYYSCPVCGFTVPELEPRLFSFNAPFGSCP
                     TCDGLGIKLEVDLDLVVPDPSKTLREGALAPWNPISSNYYPTMLEQAMQSFGVDMDKP
                     FEQLSEQEKELILYGSGDQEFHFHYVNDFGGERSIDIPFEGVVTNINRRYHETNSDYT
                     RNVMRGYMNELTCASCHGYRLNDQALCVRVGGEYGLTIGQVSELSIADHLQLLDRLEL
                     SDNESTIAKPIIKEIHDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYVLDEPSIGLHQRDNDRLIDSLKKMRDLGNTLIVVEHDEDTMMQADWLIDVGPGA
                     GDFGGQIVASGTPQQVARHKRSITGQYLSGRKSIPVPLERRAGNGRYIDIKGAAQNNL
                     QNLDVRFPLEKFIAVTGVSGSGKSTLVNSILKKAVAQRLNRNSEKPGKHRSITGIDHL
                     ERLIDIDQSPIGRTPRSNPATYTGVFDDIRELFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVPCDVCHGRRYNSETLEVHYKGKNIAEILDMTVDDALV
                     FFSAIPKIARKIQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSLYIL
                     DEPTTGLHTDDIARLLKVLERFVDDGNTVLVIEHNLDVIKSADHIIDLGPEGGVGGGQ
                     LVATGTPEEVAAVEESYTGQYLKLKL"
     gene            4915..5859
                     /locus_tag="TV188_001804"
     CDS             4915..5859
                     /locus_tag="TV188_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003085337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEL1535129.1"
                     /translation="MKQMFLSSAIEFKEIETFEPGAWIKLVNPSQEESIAIADQFNID
                     ISDLRAPLDVEETSRIAVEDDYTLIIVDVPVYEERNNKSYYVTMPLGIIVTESAVITT
                     CLHDMTLFDQFHKRKVKNFYTFMKTRFVFQILYRNAELFLTALRTIDRQSERLEAQLE
                     AATRNEELIDMMELEKSIVYLKASLKFNERIVKKLSSSTSSLKKYIEDEDLLEDTLIE
                     TQQAIEMAGIYENVLNAMTETTASIINNNQNTIMKTLALMTMALDIPTVIFSAYGMNF
                     QDNWLPLNGLSHAFWYIVLLATLLSSFVVIYFIRKKWF"
     gene            6118..6768
                     /locus_tag="TV188_001805"
     CDS             6118..6768
                     /locus_tag="TV188_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013643410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HEL1535130.1"
                     /translation="MDLQQLTKKNQEFIHIATNQLIKDGKTDDDIKALLEEVIPTILE
                     NQKKGITARSLYGAPTAWAASFSKEANQKEATPKNTNPWLMWLDTSLLFIGIVGLLNS
                     IMTFFNTNTTVTGLVSLLALGFGGGASMYATYYFVYRHMGKDKSLRPSWFKVIGALTL
                     AMLAWITLYSATAFLPKALNPQLPPVALLITGALAIGLRYLLQRKYNIQNTMAPQR"
BASE COUNT         1998 a         1792 c         1334 g         1761 t
ORIGIN      
        1 ttatgaccat tatcagcctt cggcctaagg ctcaacagcg ccacccaaga taatctgagg
       61 cacatcatgc tgaacataag caaccccttt tttatccatt agctcaatgg caaaagggtg
      121 gggacgataa tgggatttat aggtgatctt gcaaataccg gcctgaagga gggccttagt
      181 gcaattgata caaggaaagt gcgtgacata aatctctgtt ccagcagttg aaatgccctc
      241 cttagcacat tgaatcaaag cattcatctc tgcatgaaca gttctgatac aatgcccttc
      301 ttccatataa tgaccggctt cattacagtt atcagtcgcc gacacgccac cgttatagcc
      361 tgtcgcaata atgcgattgt ccttgaccaa gactgcaccg acaaatgctc gatcgcaggt
      421 tgatcgctta gatatcagct ctgcatttgc cataaaataa tcttgccatg atagcctatc
      481 tgtcatgctt tgtctcctaa tcccttctaa ctcacagcag ctaacaagcc tacgttaaaa
      541 caatcaattc ctttggtgcc ttggttaaga cctgacagcc tgtttctgtg atgacaagat
      601 cgtcctcaat acgcacaccg tatttgccgt ctaaatagat acccggttca tctgtcacca
      661 ccataccagc tagaagcctt tgatctgtct tagcaaaaaa tggatcctca tgaatatcaa
      721 gtccgatccc atgaccaatg ccatgtgtaa agtgactgcc atatcctgcc tcagtaatga
      781 gctgacgagg aatagcatca aactcacgat aggtcatgcc tgcaccagcc tttgcaatca
      841 aagcctgatt agctgcaaga accagctcat aaatctcacg ctcctggtct gtcacctgtc
      901 cgatatgaat agtccttgtc atatcactca cataatgctg ataataacag ccaaagtcaa
      961 gcgtcaaagt ctctccctgc tgaatgattt tatctgtagc acgaccatga ggcatggcag
     1021 aacgatagcc tgaggctgca atggtgtcaa aggaaatgcc tgaggcaccg tattgacgca
     1081 tgcgaaaatc caagaaatta gccacttcaa gctcacttgt ctgccccggc ttaataaagt
     1141 ccaagacatc acagaaggcc ttgtctgaaa tcgagcaggc tttagcaata atgtcaatct
     1201 cagaagcgtc cttaatcaga cgaagcgctt caataaagcc tgattgcggc agcaaagtca
     1261 cctctgaaaa ggctgcctga aggctttgag aaaaggaaaa ggacacctga tcctcaaagg
     1321 ctagactgct aagcttgtcc gcctgtagga ttgcagcaat ttcagccagc ggtgtgcggc
     1381 tctcaatgat atcaaagccc tcaatactag ccttagcaat taaggtataa cgcgaatctg
     1441 taataaaaac acgccgcttt ggactgataa agaccgtagc tgaggtccct gaaaagcctg
     1501 tcaggtaata aatattagtc agattagtaa ttaaaatagc ctccaagcct tttttttcca
     1561 gtaatgcttg gcaattgctt aagcgctgtg ctaaaaatga tgacatggta atctccttta
     1621 tcgacaaaac taccttaagt ttaccatgat ttcaacgctt ttaaaagcaa gacccattaa
     1681 agacagccaa caaaaaaagc atttctgaca gtggaccaaa aggctaatca gcttagccgc
     1741 cactaccaaa aatacccttt aaatatcacc cacgcccccc gcgaagagag ctactggcta
     1801 tctattattt aaattaaaat cacccctcat ttcaatccat gccctatcat cgttcatacg
     1861 aagatcactc tgtcaattga tgtcaggcct gcaactttac aatttcagct tcaggtactg
     1921 ccctgtgtag ctttcctcaa cagcggcaac ctcttcagga gtcccagttg caaccagttg
     1981 acctccacca acaccgcctt ctggaccaag gtcaataata tggtctgccg acttgatgac
     2041 atctaaattg tgctcaatca ctaaaacagt attaccatca tcaacaaagc gctctaaaac
     2101 cttcagtaat cgcgcaatgt catctgtatg cagccccgtc gttggctcat ctaaaatata
     2161 caagctttta ccagttgaac gcttgtgcaa ttcactagcc agcttcatgc gctgggcctc
     2221 gccacctgat agggttgtcg ctggctgccc tagagtaaca tagccaagcc caacgtcctt
     2281 aatggtctga attttacgag caatctttgg aatagctgag aaaaatacca gagcatcatc
     2341 taccgtcata tccaagattt cagcaatgtt tttgccctta taatggacct ccaacgtctc
     2401 tgaattatag cgtctgccat gacaaacatc acatggaacg taaacatctg gtaaaaaatg
     2461 catctcaatc ttgataatcc catctccaga gcaggcttca cagcggcctc ccttcacatt
     2521 aaaggagaag cgcccttttt tgtagccacg aatcttggct tcattagtct gggcaaagag
     2581 ctctcgaata tcatcaaaaa caccggtata ggtggcagga ttagagcgcg gtgtccgccc
     2641 aattgggctt tgatcaatat caatcaaccg ttccaaatgg tcaatgccag tgatagacct
     2701 atgcttgcct ggcttttcag agttacggtt tagcctttga gccactgctt ttttgagaat
     2761 gctattaacc agcgttgatt ttcctgagcc agagacccca gtcactgcaa taaatttctc
     2821 cagaggaaac ctcacatcaa gattctgcag attgttttgg gctgctccct tgatatcaat
     2881 atagcgacca ttgccagcac gtcgctccaa aggaacgggt attgatttgc gtccagacag
     2941 gtattgacca gtgatagacc ttttatgccg agcaacctgc tgaggcgttc cagaggcaac
     3001 aatctgcccg ccaaagtccc cagcaccagg tcccacatca atcagccaat ctgcctgcat
     3061 catggtatcc tcatcgtgct caaccacaat caaggtattt cccaagtcac gcattttttt
     3121 caagctatca atcaagcgat cgttatctcg ctggtgcaga ccaatagaag gctcgtccaa
     3181 aacgtaaagg acacctgaca gattagagcc aatttgcgtt gccaaacgga tacgctgact
     3241 ctctccacca gacaaggtgc ctgccgagcg agacaaggtc agataattca gaccgacatt
     3301 attcaaaaag gtcagccgat catgaatttc cttgataatt ggctttgcaa tggtgctttc
     3361 attgtctgac agctcaagcc gatctagcag ctgcagatgg tctgcaatag atagctctga
     3421 cacctgaccg atcgtcaagc catactcacc accaacacgc acacacaggg cttgatcatt
     3481 gaggcgatag ccatgacagc tcgcacaggt caattcgttc atatagcctc gcatgacatt
     3541 gcgggtatag tcactgttag tctcatggta gcgacggtta atatttgtca caaccccttc
     3601 aaagggaata tcaatgctgc gctcgccacc aaaatcattg acatagtgaa aatggaactc
     3661 ctgatcacct gagccataca ggatcagctc cttttcctgc tcgctcaatt gctcaaaagg
     3721 cttgtccata tcaacaccaa agctctgcat tgcctgctca agcatggttg ggtaataatt
     3781 tgacgagata ggattccaag gagcaagagc cccctctctc aaggtcttgc tgggatcagg
     3841 aacaactaga tccaaatcca cctccagctt gatccctaag ccatcacagg tagggcaaga
     3901 gccaaagggc gcgttaaatg aaaaaagacg aggctctagc tctggcactg taaaaccaca
     3961 taccggacag gaataatact ctgaaaacag caactcattg ccgtccatcg tatcaatcat
     4021 cagatagcca tctcccaagc gaagcgcagc ctctatcgaa tcaaaaagac gactgcggat
     4081 cccgtcctta ttgaccaagc gatcaatgac gacctctata ttgtgcattt tgcttttgga
     4141 taatgctggt acctctgaca catcaaaaat ctctccatca acacgcacgc gcacataacc
     4201 gtccttttga attttctcaa acactgtctt gtgctgaccc tttttacgac ggacaagagg
     4261 cgccaaaatc tgcatacgcg tccgctcagg caactctagc acctgctcaa caatctgctc
     4321 caccgaggaa gccgtaatag ccccatgccc attgatacaa tagggagtcc ccacacgcgc
     4381 ataaagaagc ctgaggtaat cattgatttc tgtcaccgta ccaacggttg atctaggatt
     4441 cttgctggtt gttttttggt caatagaaat agcaggacta agcccgtcta tagaatccac
     4501 atcaggcttt tccatgttgc ctaaaaattg cctagcatag gctgacaggc tctccacata
     4561 gcgacgttgt ccctcagcat agatggtatc aaaggcaagg ctagattttc cagatcctga
     4621 taagccggtc accacaacga gcttatcacg tggaatctcc acatcaatat tttttaaatt
     4681 gtgggcacgc gccccacgaa taatcaattt atcttgcatg ctcttgtgcc cccaggcacc
     4741 ctcctcatcg agatttattc cattataaca aaaatttcta ataatcagtt gccccaaaca
     4801 ccatgaattt gtagtataat agacaggtat tgagtgtttt tcaaaaaggc ttcgtctacc
     4861 tgatgacaag aagctcactt caatactgac taatcacaaa aaggagggct tgtcatgaaa
     4921 caaatgtttc tttcatcggc aattgaattc aaagaaatcg aaacattcga gccaggtgct
     4981 tggatcaaat tggtcaaccc ctcccaggaa gagtctatcg ccattgccga tcaatttaac
     5041 attgatattt ctgacctgcg tgcccctttg gacgttgaag aaacctcacg tattgctgtt
     5101 gaggacgact acaccttgat tatcgtcgac gttccggtct atgaggagcg caacaacaaa
     5161 agctactatg tgaccatgcc tttgggaatt atcgtcactg aaagcgcggt aatcaccacc
     5221 tgcctgcatg acatgacact ttttgatcag tttcataagc gtaaggttaa aaacttttac
     5281 acctttatga agacacgttt tgtctttcaa attctctacc gcaatgccga gcttttccta
     5341 accgcactaa gaacaattga ccgacaaagc gaacgcttgg aggctcagct tgaggcagca
     5401 acccgaaacg aagaattaat cgacatgatg gagcttgaaa aatccatcgt ctacctaaag
     5461 gcctccctaa agttcaacga gcgcattgtc aaaaaattat ccagctcaac cagctcactc
     5521 aaaaaatata ttgaggacga ggacctgctt gaggatacac tgattgagac ccaacaggct
     5581 attgagatgg ctggcattta tgaaaatgtc ttaaatgcca tgaccgaaac aaccgcctca
     5641 atcattaaca acaatcagaa caccatcatg aaaacattgg ctctgatgac gatggctcta
     5701 gatattccga cagtgatctt ctcagcctac ggcatgaact ttcaggataa ttggctgccg
     5761 ctcaatggcc ttagccatgc cttctggtat attgtcctgc tggcaaccct gctcagcagc
     5821 tttgttgtta tttattttat tagaaaaaaa tggttttaat aaccccattt ccaactgaaa
     5881 aagctactcc tgagctctac ctgtagacag ctcatcagct aaagcaggca ctactactgc
     5941 taaagcaaac aatcgtccca gcaagtaacg gtagctacta ctgcttgatc gtatgatcaa
     6001 gcgcaacata tcagctgcca tactagctgg caaagcaagc cagcaaggcg cccttgaggc
     6061 attatcccag gctagccctg cttacaatca tcacatcata taggagaatc ccctgtcatg
     6121 gacttacaac agcttaccaa aaaaaatcaa gaatttattc atatcgccac caatcagctc
     6181 atcaaagatg gcaaaactga tgacgacatc aaggcacttc ttgaggaggt cattccgacc
     6241 atcttagaga accagaaaaa aggcatcact gcaagaagcc tatacggggc tccaactgcc
     6301 tgggcagctt cctttagtaa agaagcaaat caaaaagaag ccacacccaa aaacaccaat
     6361 ccatggctga tgtggcttga tacctcgctt ctatttatcg gtattgttgg ccttttaaac
     6421 agtatcatga ccttctttaa taccaacact accgttaccg ggcttgtgtc cttgcttgct
     6481 cttggctttg gagggggtgc ttccatgtac gccacctact attttgttta tcgccatatg
     6541 ggcaaggaca agagccttcg tccaagctgg tttaaggtta ttggtgctct gacacttgca
     6601 atgctggcct ggataaccct ctattctgct acagcctttt taccaaaggc gctcaaccca
     6661 caattacctc ctgtagcact tctcattacc ggtgccttag ctatcggact gcgttacctc
     6721 ttgcagcgca aatacaatat ccaaaacact atggcaccgc agcgctagca gcagctccac
     6781 tgcctgagga agcacttccc tattctctct tgagggcagt tagccttttc ataccatatt
     6841 gctggcaaca ccagacactg atctacaatc gacactcctc aatcc
//
LOCUS       DARYYD010000081         6840 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.082, whole genome shotgun sequence.
ACCESSION   DARYYD010000081 DARYYD010000000
VERSION     DARYYD010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6840)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6840)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6840
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.082"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(392..4108)
                     /locus_tag="TV188_001806"
     CDS             complement(392..4108)
                     /locus_tag="TV188_001806"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pullulanase"
                     /protein_id="HEL1535131.1"
                     /translation="MMKRLRENQALFEERQLFGIRKLKLGVASVAIATAFSLGTASGQ
                     ITAAAESLTSVEPADGAVMVKSEAADQGSNELPEATDISDIAGISDVTKVSAAVNADT
                     VKEVQPVAVPLVEDQAHEETTDQSQPSSSIVSVTTDSSLETPEATSSEEPIAEQTLRL
                     HFKTLPAQDLSSLGLWVWDDVETPSDQLGGWPTGATNFSLAKTDDYGYYMDVKLSANQ
                     ANKVSFLINNTKGDNLTGDRTIDLLSPKMNEVWIDGQELSYYRPLAQGYIRINYYRSD
                     GHYDNKSLWLWGSADASMTSQQGAWPDGIDFKQVGRYGAYIDVKLADTNELGFLLLDE
                     RQTGDAVKIQPNDYIFKDLKNHTQIFLKDEDPTIYTNPYFVNTVRLIGAQQVSPSSIE
                     ASFTTLADVDKESLLKELKISTDSKEAVAITDITLDEKTHKAVITGDFSQAVATYTVT
                     FHHESFQARPNWQYKDSLYAYDGELGARVREAGAKVDLTIWSPSADKVSLVLYDKADQ
                     TKVIGNLALAKGDKGEWSITLSADSGLGISDYRGYFYHYEITRNGKSVLVLDPYAKSL
                     AAWNSELAKTDPSYKVAKAAIVDPAAIGDKELAFADIKGFHKREDAIIYEAHVRDFTS
                     DQAIANDLKAQFGTFAAFVEKLDYLKELGITHVQLLPVMSYYFVNELANKERMLTYSS
                     SDNNYNWGYDPQSYFALTGMYSTDPTDPAKRIEEFKQLVNEIHKRGMGVILDVVYNHT
                     ANVDIFEDLEPNYYHFMNADGTARTSFGGGRLGTTHYMSRRVLVDSITYLVDEYKVDG
                     FRFDMMGDHDAAAIEKAFLAAKALNPNIIMLGEGWVTYQGDEHMPEQPADQSWMSQTD
                     TVASFSDDFRNQLKSGFPNEGSPAFITGGARDIMTIFHNIKAQPTNFLADDPGDVIQY
                     IAAHDNLTLFDIIAQSIKKDPSVAANAAEIHRRLRLGNLLVLTSQGTPFLHAGQEYGR
                     TKQFKDEAYKGKVADDKVPNKSHLLVNEDGTPFEYPYFIHDSYDSTDAINHFDWAKAT
                     DTERYPESTTSQAFTKGLIALRRSTDAFRLASKAEIDQKVKLITVPNEHGIKAQDLVI
                     AYQTTASNGDVYAVFVNADSNDRTIRLTGEFQALLAGEVIVDAKQAGTEALASPEGVV
                     LTKDGVKLSGLTATIIRLRASQSDKGTLGAMTDQAAHHQEKLVAAQTAGEVSQFSAKT
                     LPKTGTSQLDALLALAGSGILAGLGGLVSKSKRR"
     gene            4588..5133
                     /locus_tag="TV188_001807"
                     /pseudo
     CDS             4588..5133
                     /locus_tag="TV188_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003030066.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1595 family transposase"
     gene            5214..5669
                     /locus_tag="TV188_001808"
     CDS             5214..5669
                     /locus_tag="TV188_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535132.1"
                     /translation="MVKHAKTNLHFELERSISRKVDSKLIAYQVSLSDGFYDKYTKLW
                     DKTYSFDFVINHRAFYAQLTKRCVYDVLLQTLEKISRKAIAKQLAELEALVDVSESKE
                     DFQIFFEKKYKLSFPDLKNCVYPKKKELSDFDQNLWIALHYNPRKERDT"
     gene            5669..5956
                     /locus_tag="TV188_001809"
     CDS             5669..5956
                     /locus_tag="TV188_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535133.1"
                     /translation="MTTWYDYMVRASEHSGSDGDLWFRYLYKVIKDKETKLTTDDVEQ
                     LLKNPNLTPFQKVTLQDALTEGTHTREHVLQANRKSQPKDILKLFREGNYG"
     gene            5949..6497
                     /locus_tag="TV188_001810"
     CDS             5949..6497
                     /locus_tag="TV188_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="HEL1535134.1"
                     /translation="MDKKILFKALNTELAKENISLDIICVGGFVLEYYNLRGTQDIDA
                     FYQEGVNIRQMIKKVGDEFGVNEPDELWLNNSVANLNRIPPKTICETVFHYSNLIVLV
                     PPLSYILGMKLESGRDRDRQDAGDIIKLANIRSPKKLINTLEEYDFQPDISMILEVFE
                     IAYGMEWLANYMTEHPEEFRHY"
     gene            complement(6676..>6840)
                     /locus_tag="TV188_001811"
     CDS             complement(6676..>6840)
                     /locus_tag="TV188_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1535135.1"
                     /translation="KPEAQKGDKPAVPKAMEHKLPSTGEATAPFFTAAALAVLASLGV
                     AVVSRKRKKH"
BASE COUNT         2067 a         1524 c         1332 g         1917 t
ORIGIN      
        1 aacagcacag cttatttaca aacctataaa catcatcttt atattctaaa tatatgtcct
       61 caaattccaa cagcttgtct cctctcaata cacccttaac cattagaccg tccaatctgc
      121 caaaagttac agattaattt aatttttagt ataagctgtc atcaagtcag ataaatagta
      181 atgatctatc atcttattat tgactcaaac gacaaattat attgcatttt agtataagct
      241 gtcatcaagt caggtaaata acaaggacat atcatctaac atttgatcca gacaaaaaag
      301 acctgattct gtaatataca gaaccaagtc tttctcaata gacattgact agatgattga
      361 tttatagcga catagctaga taggctatga cttaccgtct tttggatttg gagacaagcc
      421 cgccaagacc tgccaagata ccactgccag caagagccaa taaagcatct agctgactag
      481 tgcctgtttt agggagagtc ttagctgaga actgagaaac ctctccagca gtctgagcag
      541 caactaattt ctcctgatga tgggctgctt gatcagtcat tgcacctaaa gtccccttat
      601 cagactggga cgccctaaga cggataatgg tagctgttaa gcctgatagc ttgaccccgt
      661 ccttggttag cacaaccccc tcaggacttg ccagcgcctc ggtgcctgct tgcttggcat
      721 cgacgataac ctcaccagca agaagagcct gaaactcacc agttagccta atggtacggt
      781 cattgctatc agcattgaca aagacagcat aaacatcacc attgcttgct gttgtctgat
      841 aagcaatcac caaatcctgt gccttgatcc catgctcatt tggaacagtg atcagcttga
      901 ccttctggtc tatctcagcc ttacttgcca agcgaaaggc atctgtcgaa cggcgcagcg
      961 caatcaatcc cttagtaaag gcctgacttg tcgtgctttc agggtagcgc tctgtatccg
     1021 ttgcctttgc ccagtcaaaa tgattaatgg catctgtcga atcataggaa tcatgaataa
     1081 agtatgggta ttcaaatggt gttccgtcct cattgaccaa gaggtgtgat ttatttggca
     1141 ccttgtcatc agcgaccttg cccttatagg cttcgtcctt aaattgcttt gtacgaccat
     1201 attcctgacc agcatgtagg aaaggggtgc cttgagaggt tagcaccaag aggttcccta
     1261 ggcgcaagcg acgatgaatc tctgccgcat ttgctgcaac agacggatcc tttttaatag
     1321 actgggcgat aatatcaaac aaggtcaggt tatcatgtgc agcgatatac tgaatcacat
     1381 cacccggatc atcagccaaa aagttagtcg gctgagcctt gatattatga aaaatggtca
     1441 tgatatccct agcaccgccc gtaataaagg ctggagagcc ttcatttgga aagcctgatt
     1501 tgagctgatt gcgaaaatca tctgagaagg aggcaacggt atctgtctgt gacatccagc
     1561 tttggtccgc aggctgctca ggcatgtgct catcaccctg ataggtgacc cagccctcac
     1621 caagcatgat gatattcgga ttaagtgcct tagctgctaa aaaggctttt tcaatagctg
     1681 ctgcatcatg gtcccccatc atgtcaaaac gaaaaccatc aaccttatac tcatccacca
     1741 gataagtaat cgaatccacc aaaacacgac gactcatgta atgcgttgtc ccaagtcgtc
     1801 caccaccaaa tgaggtccta gcagtgccat cagcattcat aaagtgataa taattcggct
     1861 ccaggtcctc aaaaatatca acattagctg tatgattgta gaccacatca aggataaccc
     1921 ccataccacg cttatggatt tcattaacaa gctgcttaaa ttcctcaatg cgcttagctg
     1981 ggtcggttgg atcagtcgaa tacataccag tcaaggcaaa atagctttgt ggatcatagc
     2041 cccagttgta attattatca cttgagctgt aggtcagcat acgctccttg ttggccaatt
     2101 cgttgacaaa ataatagctc atcacaggca gcagttgaac atgcgtaata ccaagctcct
     2161 tgagataatc caacttttca acaaaggcag caaaagtccc aaattgagcc tttagatcat
     2221 tagcaatcgc ctgatctgag gtaaaatcac gaacatgtgc ctcatagata atggcgtcct
     2281 cacgcttatg aaagccctta atatcagcaa aggccagctc cttatcccca atagcagcag
     2341 gatcaacaat ggccgcctta gccaccttat aggacgggtc tgtcttagca agctcgctgt
     2401 tccatgccgc taacgatttg gcataagggt ccagcacaag gacagacttg ccatttctag
     2461 taatctcata atgatagaaa tagcctctat aatctgaaat cccaagtccg ctatctgctg
     2521 atagagtgat tgaccactct cccttatcac cctttgctag agcgagatta ccaatcacct
     2581 tggtctgatc agccttatca tacaaaacaa gtgacacctt atcagcactt ggtgaccaaa
     2641 tcgtcagatc aaccttagca cctgcttctc tcacacgcgc tcctagctca ccgtcataag
     2701 catacaggct atccttgtat tgccaatttg gcctagcctg gaagctctca tgatgaaagg
     2761 tcaccgtata agtggccact gcttgactaa aatcacctgt gatgacagcc ttatgagtct
     2821 tttcatctaa ggtgatatca gtaatagcaa ctgcttcctt actgtcagtg ctgattttta
     2881 attcttttaa aaggctttcc ttatccacat ctgctagagt cgtaaagctc gcctcaatac
     2941 tgcttgggct gacctgctga gcaccgatta atctaactgt attaacaaaa taagggttcg
     3001 tataaatggt tggatcctcg tctttcaaga aaatttgggt gtgattcttt aaatctttaa
     3061 aaatataatc attgggctga attttaacag cgtcacctgt ctgacgctca tctagcaaga
     3121 gaaagcctag ctcattggta tcagctagct tgacatctat ataagcacca tatcgaccga
     3181 cctgcttaaa atcaatacca tctggccaag cgccctgctg actagtcatt gacgcatcag
     3241 cacttcccca aagccagagc gatttgttgt cataatggcc atcactgcga taataattga
     3301 tacggatata gccctgagcc agcggccgat agtaagacag ctcctggcca tcaatccaga
     3361 cctcattcat cttagggctg agaaggtcta tggttcgatc gcccgtcaga ttgtctccct
     3421 tagtgttatt gatcaaaaag ctaaccttat tggcttgatt ggctgaaagc ttaacgtcca
     3481 tgtaatagcc atagtcatct gtcttcgcta gactaaaatt ggtagcccca gtcggccagc
     3541 ctcccagctg atcagatggt gtctcaacat cgtcccacac ccaaagacca agcgaggata
     3601 ggtcttgagc tggcagggtc ttgaaatgca gccgcaaggt ctgctccgct atcggctcct
     3661 ctgagcttgt agcttctggt gtctctagag agctgtctgt cgtaacagac actatcgatg
     3721 atgaaggctg agactggtct gtagtttcct catgcgcctg atcctctaca agaggtacag
     3781 ctactggctg aacttccttg acagtatcag cattgacagc agctgacacc ttagtcacat
     3841 cagaaatacc agcaatatca ctaatgtcag tagcttctgg tagctcattt gagccttggt
     3901 cagcagcctc tgacttgacc atgaccgcac catcagcagg ctcaacactc gtcagactct
     3961 cagctgctgc tgtgatctgc ccactagctg tccccaaaga aaaagcggtt gcaatagcta
     4021 ccgaagccac tccaagctta agcttacgaa tgccaaataa ttgacgctct tcaaacagcg
     4081 cttgattttc ccttaacctt ttcatcattc ctccgtcctt atcctgatag ttattaacac
     4141 cttaagtata caaaagaaat cacaatagtg caatcgtttt ctttattgaa aacaatgata
     4201 tttatgaaca aattagacaa gaatcaacgc aagcgatttc cttactgata aatacctgct
     4261 cccctcacta agaccagccc actgcaaagc agaaaagtag cctaaagagc cttagtaaca
     4321 gataaatgag cttaatgttg cttcatcaac tagctggctg caaccgtttt gctctgatgt
     4381 ggtaacgtct tgtcatcatg actaagcttg acaaaaaacg ctgttagtta cataatcaac
     4441 ggtgcttggt agccttccat tactcctttg attgttatac cctaatgata cacaaaacct
     4501 cagtttttat agtagaatat tacactttgt tttgacaaag atgtttaatc ttgctaaaat
     4561 aaacttatca atgagggagt accaatgatg acattcgaat tcacatcgtt attcgattta
     4621 caaactgctt ttccaacaga gcaggcttgc ataaatcatt tagaaaatat cacttggggt
     4681 gacgtggtga tcagcccttt tgacgctacc tcaaaggtct ataaatgcaa gggaaataaa
     4741 taccgttgca agaatacagg gaagtatttc actgtcaaaa caggtactct ttttgataat
     4801 actaagatta agctacaaaa atggtttatg gcaatctggc ttgtgacttc tcacaagaga
     4861 ggaatctcct cagtgcaatt atcaaaagag attgcagtga cacaaaaaac agcatggttc
     4921 atgttacagc gtattcgtaa atgctttggc tctgaaaact gagatccact tggtgacgtc
     4981 gttgaagtag ataaaactga tattgatggt aaaaataaga accaccatga tcctaagaag
     5041 gcaaaaacgt tcaagaacca tccttctctg aaagataagt cggcagttat tggaatggtg
     5101 caacaaaaaa gtaaggccaa cgctcataca atactcgtga ttactctgat agtcggcgtt
     5161 ttatctttta tcagctaatg ctgatatgcg aacaacttat aaggagctga tcaatggtta
     5221 aacatgcaaa aactaaccta cactttgaat tagaaagatc tatctctcgc aaagttgata
     5281 gtaaattgat agcctatcaa gtcagtcttt cagatggctt ttatgacaaa tacaccaaat
     5341 tatgggataa aacctattca tttgattttg tcatcaacca tcgtgcgttt tatgctcagt
     5401 tgaccaaaag atgtgtttac gatgtccttt tgcaaacttt ggaaaaaatc agtagaaaag
     5461 ccattgcaaa gcaactagca gagcttgaag ccttggttga tgtttcggaa agtaaggaag
     5521 actttcagat atttttcgag aaaaaataca aactatcatt tcctgatttg aagaattgtg
     5581 tttatccaaa gaaaaaggaa ctttccgatt ttgatcaaaa cctctggata gctctacatt
     5641 ataaccctag aaaggagagg gatacataat gacaacatgg tatgattaca tggtaagagc
     5701 cagcgaacac tctggaagtg atggagacct ctggtttcgt tacctttaca aggttatcaa
     5761 agacaaagaa accaaactaa ctactgatga tgtggagcag ttattaaaaa atccgaatct
     5821 aactcctttt cagaaggtaa ctctgcaaga tgctttaaca gaaggtacgc atacaagaga
     5881 gcatgtttta caggcaaacc gtaaaagtca gccaaaggat attttgaaac tctttagaga
     5941 gggaaactat ggataaaaaa atcttattca aagctctgaa tacagaacta gctaaagaaa
     6001 atattagcct tgacattatc tgtgtcggtg gttttgtcct tgaatattac aatctgcgag
     6061 gaacacaaga tatcgatgcc ttttatcaag aaggtgttaa catcaggcag atgatcaaaa
     6121 aggtgggaga tgagtttggc gttaatgaac ctgatgagct ttggcttaat aattcagttg
     6181 ccaatcttaa tagaatacca cctaaaacga tttgtgagac agtatttcac tattctaacc
     6241 taattgtcct tgtcccaccc ttgtcttata ttcttggaat gaagctagaa agcggacgag
     6301 atagggatag acaagatgcc ggagacatta ttaagctagc taatatccgt tcccctaaaa
     6361 aacttatcaa tacacttgaa gagtatgatt ttcaacctga tatttcaatg attttagaag
     6421 tctttgaaat agcttatggc atggaatggt tagcaaacta tatgaccgaa cacccagaag
     6481 aatttaggca ttattaaaag acgatttctg tttggaagtc gccttttttg atgtttttga
     6541 aaacaccttg agattagtct aaactaatct ccataagcaa aaaacagctt agccccgtct
     6601 gggagtaagc tgtttttgct gtaatgtatg agataattag gctaacatca atcattacat
     6661 aaagggaata aagggttaat gtttcttgcg tttgcgtgat actacagcta cgcctagact
     6721 tgccaatacg gcaagggctg ctgctgtaaa gaatggagct gttgcttctc ctgttgacgg
     6781 aagcttgtgt tccattgctt taggtaccgc tggtttatct cctttctgtg cttctggttt
//
LOCUS       DARYYD010000082         6827 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.083, whole genome shotgun sequence.
ACCESSION   DARYYD010000082 DARYYD010000000
VERSION     DARYYD010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6827
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.083"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(54..371)
                     /locus_tag="TV188_001812"
     CDS             complement(54..371)
                     /locus_tag="TV188_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535136.1"
                     /translation="MADRIVEEVAIYRKLREMDDAEQDFLRQKRAYQKREDSLSERRH
                     VLNDLINSEYQKMSVFLKRLDLSANAASDFFNELGRLKDQSNAEFHLFLKLGKILNNK
                     SLG"
     gene            complement(353..1642)
                     /locus_tag="TV188_001813"
     CDS             complement(353..1642)
                     /locus_tag="TV188_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535137.1"
                     /translation="MAISDSSYNELAKQVYNVEPSKAKSNGDLVIVAGKTVKDPITKR
                     QYRVLLVQDNNNDAHKTNDNGMQAMAVAPIVKGDIDTSQVVIAYAGTNAADSRDLDTD
                     WQLLIRGNQDDLVSGNIDGGNFVIAENQLRSAQKFYQQVKRKYPHSALTTTGHSLGAY
                     LALIVAAEHKIPATTFNGPDPVRGMSAEAITWVKANSNMYNNFRINFDGIGNFGAYFG
                     TDDLAISRNVDAMLLSANPLYYHDLGAYRFNQKGQIVDRDGKLIGTQYLVSRAYLTVL
                     ASKKSMSSYNQLKKHWQSTGKGISSSEELFLDAAQGMILGSSMAKAAREGADEALDHK
                     TVADAKLMEVWSAIDFNSFHELPYYEVQALFASYGITYDRFVQDFQDYTQSKVSKLSA
                     LATDFENLNRDIQTVIDSKLETDRQLAGEFRAWQTEL"
     gene            complement(1644..2087)
                     /locus_tag="TV188_001814"
     CDS             complement(1644..2087)
                     /locus_tag="TV188_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535138.1"
                     /translation="MMTVKTNKQRLWLGLIIVIGAIIMVFRLNGKRTEEQQKRDLETS
                     IAKLLVHDYEGVKEVKFTGWGHSRETGSWGTIVIINGENEIGFSFDGLSSLEKIRGIV
                     TDDDTEKMEKPETDTKPRIMDRIDKINKTSLVGVTVIYSKDNQED"
     gene            complement(2452..6003)
                     /gene="smc"
                     /locus_tag="TV188_001815"
     CDS             complement(2452..6003)
                     /gene="smc"
                     /locus_tag="TV188_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEL1535139.1"
                     /translation="MFLKEIQMQGFKSFADKTKIIFDKGVTAVVGPNGSGKSNVTESL
                     RWALGEASAKSLRGGKMPDVIFAGTEHRSPLNYAEVAVVLDNSDAFIKNAQKEIRVER
                     HIYRNGDSDYLIDGKKVRLRDIHELFMDTGLGRDSFSIISQGRVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRKKETQTKLNQTQDNLDRLDDIIYELEHQAGPLERQAKTARQFLAL
                     DADRKQLQLDILVKDIEQDRMEQEAQEKALVALREDLAAYHRKRQSLEAENHRLKTKR
                     QKLSAVAEQTQADLLELTKVISDLERQIDLIKLDLSQKQEKKTEASQRRQQAQEQLLA
                     FQQEHQQKSRQLDEIHQALAEFNTKVSELSQELERFSSDPDQLLEALREDFVGLLQQE
                     ADVSNQLTAIVAQLDKESQAKASQAQEYQVLQEKVNQLSQDTQTALLAYQASQSRLEQ
                     LLADYQELAKTVEALEQDYHQGQTRLFDLLDQKKAKEARRASLVSIQKNHSQFYAGVR
                     AVLQAAGKLDGILGAVSEHLTFDSQYQTALEIALGASSQHIIVADEAAAKRAIAFLKA
                     NRQGRATFLPLTTIKARQLSEVTLKQLRACQGYLGTADSLVTYEPSLVAIVQSLLGVT
                     AIFDTIDHANQAAKQLHYKVRIVTLDGTELRPGGAFSGGTNRHNSTTFIKPELEQIEK
                     ELALLSEQIKESEKAVAAVQADLKAKKAAQADTKLAGEQARLVEQKTQLAYQQLAEKL
                     ADSKELLELLSNRQTGQSSERLLSEKARLEEALQLLADEKSALTSEIEQIKENKDTIK
                     QKKDQLSQELSQARLKERDLLNEKKFEAANQRRLETMIAQGQKELANLETVLSHQVSQ
                     EAIDQLPHLENQLTEANQDKIKTQERFIQLRFEGEDYDARLEELEAQLLKEAKKNEAF
                     IRQQARLEADLEQVIGRLRQHARSLSEELQLSLEEAKEQASPINDTDMAAARQKLQQV
                     QQSIRALGPINSDAIAQFDEVSERLAFLNGQRADLIKAKNLLVDTIGNMDHEVKARFR
                     VTFEAIRDSFKETFRQMFGGGSADLMLTETDLLSAGVDISVQPPGKKLQSLNVMSGGE
                     KALSALALLFAIIRIKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRK
                     GTMAAADSIYGITMQESGVSKVVSVKLKDTQDLTYLS"
     gene            complement(6004..6696)
                     /locus_tag="TV188_001816"
     CDS             complement(6004..6696)
                     /locus_tag="TV188_001816"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEL1535140.1"
                     /translation="MKKLEALLENSFNIRFDDKRLLETAFTHTSYANEHRLLNISHNE
                     RLEFLGDAVLQLIISEYLFAKYPKQTEGDMSKLRSTIVREESLAGFSRYCSFDAYIKL
                     GRGEEKSGGRHRDTILGDLFEAFLGALLLDKGIEEVRRFLNQVMIPQVEQGTFEKVKD
                     YKTCLQELLQAKGDVVIDYQVISETGPAHAKQFEVAVLVGEDHLSKGTGRSKKLAEQD
                     AAKNALAQLSEV"
BASE COUNT         1821 a         1697 c         1268 g         2041 t
ORIGIN      
        1 atttgaatta caagatgcta aattgcaagt aaaagttagt catcctatag aaattatccg
       61 agtgacttgt tgttcaaaat tttccccaat tttaaaaaga gatgaaactc tgcgttggat
      121 tgatccttta agcgacccaa ttcattgaaa aaatctgatg cagcattggc agataggtct
      181 aaacgcttca aaaaaacact catcttctgg tactcagagt tgatcaaatc atttaagaca
      241 tgtcttcttt cagataagct gtcttcacgc ttctgatagg ctcttttctg gcgtagaaag
      301 tcctgctcgg catcatccat ctcccgaagc ttacgataaa tagccacttc ctctacaatt
      361 ctgtctgcca tgctctaaac tctcctgcta actgacgatc cgtttcaagc ttgctatcaa
      421 taaccgtctg aatatctcta ttcaagtttt caaagtctgt ggccaaggct gacagcttgc
      481 tgaccttgga ttgagtatag tcctgaaagt cttggacaaa gcggtcatat gtgataccat
      541 aagaagcaaa taaggcctgc acctcatagt agggcagctc atgaaaagag ttgaagtcaa
      601 tcgccgacca cacttccata agctttgcgt ctgcaaccgt tttatgatcc agagcttcat
      661 cagccccctc tcgagcagcc ttagccatgg acgagcctag gatcattccc tgtgccgcat
      721 ctaaaaagag ctcctcagaa ctactgatcc ccttgccggt agactgccag tgttttttga
      781 gctgattgta gcttgacatg ctcttttttg aggcaaggac agttaaatag gcccgactca
      841 caaggtattg tgttccaatg agcttaccgt ctctatctac aatctgaccc ttttgattaa
      901 aacgataagc tcctaaatcg tgataataca aggggttggc tgataagagc atagcatcga
      961 cattccgaga aatagctaaa tcatcagttc caaaataggc accaaaattg ccaatgccat
     1021 caaaattaat gcggaaatta ttgtacatat tgctattagc cttaacccat gtgatagctt
     1081 cagctgacat gccgcgaaca gggtctggac cattaaaggt tgttgctggg atcttatgtt
     1141 ctgcggcaac tattagtgct agataagctc cgagagagtg acctgtggtt gttaaggcag
     1201 aatgagggta ctttcttttg acctgttgat aaaacttttg agcagatcgt aattggtttt
     1261 cggcaataac aaaattgcca ccatcaatat tgccgctgac taaatcatct tgattgcccc
     1321 gaatgagcag ctgccaatcc gtatcaagat ctctggaatc cgcagcattt gtccctgcat
     1381 aggcaatcac aacctgagag gtatcgatat cacctttaac aataggggct acagccattg
     1441 cctgcatacc gttgtcattg gttttatggg catcgttgtt attgtcctga actaagagga
     1501 ctcggtattg tcgtttagtg ataggatctt ttacagtttt accagcaaca ataacaaggt
     1561 ctccatttga tttagctttg ctaggttcga cattataaac ctgtttagcc aactcattat
     1621 aactactatc cgatatcgcc atattaatcc tcctgattgt cctttgaata aatgacagta
     1681 acacctacaa gagatgtttt attaatcttg tcaatcctat ccataattct tggtttggta
     1741 tcagtttcag gcttttccat cttttctgta tcatcatcag taacaattcc tcgtattttc
     1801 tcaagactag acaagccatc aaacgaaaag cctatttcat tttctccatt tataatcact
     1861 atcgttcccc acgaacctgt ttcccgagaa tgtccccagc ctgtaaactt aacttcttta
     1921 accccttcat agtcatgaac cagcagctta gcaatactgg tttccaagtc ccttttttgt
     1981 tgttcctctg ttcttttgcc attcaaacga aaaaccatta tgatcgctcc tattactatt
     2041 attaagccta gccatagcct ttgcttattg gtcttaactg tcatcatgtc ctcctttcac
     2101 tcttttgcta tgcgtccgtc actctaagga aggcagcatg actaattagg gtgaaatcaa
     2161 cgccaaatct tatttatatt attctcattt tgtaattaaa ttataatata cagacatcta
     2221 cttgtcaata tattatgtcc ttagttactt ttttggtata ttttaatcaa aacaagccgt
     2281 actaagttcc aggagcatgt caaaaacagc agcttactgc tagccaatcc ttgtgctttg
     2341 tcctttggaa agccaaaaaa cctaccatga cgataggttt ttttatagct tattcttggt
     2401 tatcatctgc tacatgtaga aatacagcta aaactaagct ctgtcctaga gttatgacaa
     2461 gtaagtcaga tcctgcgtat ccttgagctt aacagatact accttagaaa caccagattc
     2521 ttgcatggta atcccataaa tactgtctgc tgctgccatt gtccccttgc ggtgggtaac
     2581 cacgataaac tgactatcct tgtcaaaacg attgagataa tctccaaaac gcttgacatt
     2641 ggcctcatca agggccgcct caacctcatc taaaatcaca aagggaatgg tcttaatgcg
     2701 gataatagca aataaaaggg ctagcgctga taaggctttt tctccgccag acatcacatt
     2761 caaagattga agctttttac caggcggttg cactgaaata tctactccag cagaaagcag
     2821 atcagtctct gtcaacatca agtccgctga gcccccgcca aacatctgcc taaaggtctc
     2881 cttaaagcta tcacgaatag cctcaaaggt aaccctaaag cgtgccttaa cctcatggtc
     2941 catattgcca atcgtatcta ccaagagatt cttggccttg ataaggtcag ccctttgacc
     3001 atttaagaag gccaaacgct cactaacctc atcaaattga gcaatagcat cactattgat
     3061 tgggcctagg gcacgaatgc tttgctgaac ctgctgcaat ttctgtcttg ctgctgccat
     3121 gtcagtgtca ttgattgggc ttgcctgctc cttggcctcc tctaagctta gctgaagctc
     3181 ctctgatagg cttctagcgt gctgccgcaa acgaccaata acctgctcta agtcagcctc
     3241 cagtcttgcc tgctgacgaa tgaacgcttc atttttcttg gcttccttaa gcaattgagc
     3301 ctctagctcc tccagtctgg cgtcatagtc ctcaccttca aagcgcagct gaatgaagcg
     3361 ctcctgagtc ttgatcttgt cttgattagc ctctgtcagc tgattttcta ggtgaggcaa
     3421 ttggtcaatg gcctcctgac taacctgatg tgataaaaca gtctccaaat tagctaattc
     3481 cttctgaccc tgagcaatca tcgtctccaa gcgacgctgg ttagctgctt caaacttttt
     3541 ctcgttgagc aaatctcgct ctttaagacg agcctgagat aattcctggc taagctggtc
     3601 cttcttttgc ttaatcgtat ctttattttc cttaatttgc tcaatttctg acgttaaggc
     3661 tgatttttca tcagctagga gctgcaatgc ctcctccagc ctcgcttttt ctgataataa
     3721 gcgctcacta gactgaccag tctgacggtt gctgagaagc tctagcagct cttttgagtc
     3781 agccagcttt tctgctagct gctgataggc caattgtgtt ttttgctcga ccagtcttgc
     3841 ttgctcacca gccagcttag tatcagcctg cgcagccttt ttagccttca aatcagcctg
     3901 tacagcagct actgcttttt cagattcctt gatctgctca gaaagcaagg ctaattcctt
     3961 ctcaatctgc tctagctctg gcttgataaa ggttgtgcta ttgtgacgat tagtcccccc
     4021 tgaaaaggca ccaccgggac gcagctcggt accatcaagc gttacaatcc tgaccttata
     4081 atgcagctgc ttagctgcct gattagcatg atcaatggta tcaaaaatag ccgtcacacc
     4141 taacaggctt tgtacaatag cgaccaaaga gggctcatag gtcaccaaag aatcagctgt
     4201 gcctaaatag ccctgacaag ccctgagctg cttgagagtc acctcagaaa gctgacgggc
     4261 cttaatcgtt gtcagaggta aaaaggtcgc acgcccctga cgattagcct ttaaaaaggc
     4321 tatcgctcgc ttggctgctg cctcatctgc cacgataata tgctgactac tagctcccaa
     4381 agcaatctca agtgccgttt gatactgact atcaaaggtc aaatgctcac taactgctcc
     4441 taaaatacca tctagcttac cagcagcctg aagcactgcc ctaacacctg cgtaaaattg
     4501 actatgattt ttttggatag aaaccaaact agccctacga gcctccttgg cttttttctg
     4561 atccaacaaa tcaaaaagcc ttgtctgtcc ctgatgataa tcctgctcca aggcctcaac
     4621 tgtctttgct agctcttgat aatcagctag gagctgctca agtcttgatt gactagcttg
     4681 ataagccaaa agagcagtct gggtgtcctg actgagctga ttgaccttct cttgtaggac
     4741 ttggtattcc tgcgcctgac tggctttcgc ctgactttcc ttatccagct gcgctacaat
     4801 agcggttaat tggtttgaca catcagcctc ttgctggagc agaccaacaa aatcctcacg
     4861 aagagcctca agcagctgat ctggatcgct agaaaatcgc tcaagctcct gagaaagctc
     4921 gctgaccttg gtattaaact cagctaaggc ttgatggatt tcatctagct gacgactctt
     4981 ttgctgatgc tcctgttgaa aggcaagcaa ttgctcctga gcctgctgcc tgcgctgact
     5041 ggcttctgtt ttcttttcct gcttttgact aaggtccagc ttgatgaggt caatctgtcg
     5101 ctccagatct gatatgacct ttgtcaattc tagcaaatca gcctgcgtct gctcagctac
     5161 agcagagagc ttttgccgct tggtttttag acggtgattt tccgcctcta gactctgacg
     5221 cttcctatga taggccgcta gatcctcacg aagagctact aaggcctttt cttgagcctc
     5281 ctgctccatg cggtcttgct ctatatcctt gaccaaaata tccagctgca gctgcttacg
     5341 atcagcatct aaggctaaaa attgcctagc agttttcgcc tgtctttcta gaggaccagc
     5401 ttgatgctca agctcataga taatatcgtc taagcggtca agattatctt gagtttggtt
     5461 tagcttagtt tgcgtctcct tcttgcgggt cttgtatttc aaaactccag ctgcctcttc
     5521 aaagatggcc cgtctttcct ctggcttact attgaaaatc tcctcaacac gaccttgaga
     5581 aataatagag aacgaatcgc gccctagtcc tgtatccata aacagctcgt gaatatctct
     5641 tagcctaact tttttgccat caatcagata atcactgtcg ccattgcgat agatatgcct
     5701 ctccacacga atctctttct gagcattctt aataaaggca tctgaattat ccaagacaac
     5761 agccacctct gcataattca agggactccg atgctcagtt ccagcaaaga tcacatctgg
     5821 catcttgcca ccgcgcaggc ttttggcact ggcctcacca agtgcccaac gaaggctttc
     5881 tgtcacatta ctttttccag agccatttgg ccctacaaca gctgtgaccc ccttatcaaa
     5941 gataatcttg gtcttatctg caaaagactt aaagccctgc atttgtattt cttttaaaaa
     6001 catttagacc tcactaagtt gggccagggc atttttagca gcgtcctgct ctgccagttt
     6061 tttagatcta cctgtcccct tgctaagatg atcctcacca accaatacag ctacctcaaa
     6121 ttgcttagca tgagctggtc cagtctcgct aatcacctga taatcaatca caacatcacc
     6181 cttagcctgt aacaactcct gcaagcaggt tttataatcc ttgaccttct caaaagttcc
     6241 ctgctcaacc tgtggaatca taacctgatt taaaaagcga cgaacctctt caatgccttt
     6301 atccaaaaga agagcaccca aaaaagcctc gaacaaatcg cctaaaatcg tatcacgatg
     6361 acggcctcct gatttttcct cgcccctgcc aagcttaata taagcatcaa acgaacaata
     6421 gcgtgaaaag cctgctaagc tttcctctct gacaatcgtt gatctgagtt ttgacatatc
     6481 accctcagtc tgcttaggat acttggcaaa gaggtattct gaaataatta actgtagaac
     6541 ggcgtctcct aaaaattcca aacgctcatt atgtgaaatg tttaggaggc gatgctcatt
     6601 agcataagag gtatgtgtaa aggcagtctc tagtaatctt ttatcatcaa aacggatatt
     6661 aaaagagttt tccagcaggg cctcaagctt tttcatcatg acaaatctcc ttttctaatg
     6721 tccttataaa ccattctatt ataacaaaaa tccacttgaa aggcttatca caagtggatt
     6781 tttcagaaat attgtaccaa ataggcacga gctattgact gctgcta
//
LOCUS       DARYYD010000083         6476 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.084, whole genome shotgun sequence.
ACCESSION   DARYYD010000083 DARYYD010000000
VERSION     DARYYD010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6476
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.084"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..436)
                     /locus_tag="TV188_001817"
     CDS             complement(<1..436)
                     /locus_tag="TV188_001817"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535141.1"
                     /translation="MKKLVLASAAALVLAGATVSTGTVSANSSRYNYTGWNQGGYSWK
                     YLRLRNKNPYSRRTLTEDYSDQRKNEAKDSIKELSKLSDKEKKNFADRIDALTDTYAI
                     SSILSEAKNKNNDYLEFDKEYEALFNSNKYKLEIEKIKDRVYF"
     gene            complement(623..3124)
                     /locus_tag="TV188_001818"
     CDS             complement(623..3124)
                     /locus_tag="TV188_001818"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEL1535142.1"
                     /translation="MTFYNHKAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREINTTDPSYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLADLEEVDWPESIKD
                     MQRNWIGKSTGANVTFKVKDTDKDFTVFTTRPDTLFGATYAVLAPEHALVDSITTAEQ
                     AQAVAEYKRQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAIMAVPAHDERDWAFAKQFNLEIIPVLEGGNVDEAAYTEDGIHINSDFLDGLDKACA
                     IAKMVAWLEETGVGHEKVSYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPEQDLPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NDEQLADKDLLKQWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVDKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGARKFLDRVYRLITTKEIVAENSGALD
                     KAYHETVKAVTEQIEGMKFNTAIAQLMIFVNAANKEDELYVAYAKGFVQLLAPFAPHL
                     GEELWQILTASGQSISYVAWPTHDDSKLVENDVEIVVQIKGKVKAKLVVAKDLSREEL
                     EKVALAHDKIQAEIAGKEVAKVIVVPNKLVNIVVK"
     gene            complement(3713..4576)
                     /locus_tag="TV188_001819"
                     /pseudo
     CDS             complement(3713..4576)
                     /locus_tag="TV188_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514825.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(4858..6375)
                     /locus_tag="TV188_001820"
     CDS             complement(4858..6375)
                     /locus_tag="TV188_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1535143.1"
                     /translation="MSIENLFTKQQWRELELITLLSETKNPLYYKDACQMLDCSVLTL
                     QSCITNSVFMEDLGKLFYKDSQFHIHYNHQSGLKEVYRRALLESPSLQLMSALFFDDF
                     ASLDDLAEALFISLSTLKRLIRKTNLYLKEHFDIIISAKPIRVVGDEYNIRLFYIKYF
                     SEAYTFSEWPFASLLNENHHEQFVQLMASLIEVKIDFAIFRQLKLLSAVNLIRYLKGF
                     KIGKHKALSSLSLELLQDSQEMKKLSHLFVLKFSVPLDELVLSEMFSNYLDDDLVLEK
                     SLQVDKVKEEVPGPQSLLSWIDLLSEMEGATGIVLPNKYEVARYLHATVILGVEDISE
                     SFLIYDYKKDYLAFFKEHYTYVYFRFTDYVKRLFKDGDMELATNLLNNLVYSLLIAWE
                     NFFLTMCELMKKPKLLIIERSHGSTGSFLKKYIGEFFEITIFDKLTIEALCLQHDYDV
                     IITDTVIRGCEHADIFFFSRFVPTVIVAKLNHYLRKRMGSIFETKTTNKLGNIGY"
BASE COUNT         1825 a         1473 c         1203 g         1975 t
ORIGIN      
        1 caaagtacac acgatccttt attttctcta tttctaactt atacttattt gaattgaata
       61 aagcctcata ttctttatca aattctaaat agtcattatt cttattttta gcttctgata
      121 gaatagagct gattgcatag gtgtcagtca aagcatcaat tctatcagca aaattctttt
      181 tctctttatc actaagctta ctcaattctt taatactatc ttttgcttca ttctttcttt
      241 gatcagaata gtcttctgta agggtacgac gtgaataagg atttttattt cttaggcgca
      301 aatatttcca tgagtaccca ccttgattcc aaccggtata attatatctt gaactattcg
      361 cacttactgt tcctgtactt acagttgctc ctgctaatac aagtgctgct gcactggcta
      421 aaactaattt tttcacgttg aaaaatcctc catttattaa ataagtttag ggttttattt
      481 tactattatc ttcaagcttc ttcaatatca gttttaatag cgtgttacaa aacaagaata
      541 accactcatg taaacgagtg gttatcagct ttttatagta ttgggctcaa aattataagg
      601 aaggcatttt ttgctagggt ctttatttca ccacaatatt aacgagctta ttaggaacaa
      661 cgatgacctt tgccacttcc ttgcctgcaa tttcagcctg tattttatca tgtgctaggg
      721 ctactttttc tagctcttct cttgagaggt cttttgccac gacaagctta gccttgacct
      781 ttcctttaat ttgaacaacg atttcaacat cattttcaac gagcttacta tcgtcatggg
      841 ttggccatgc aacatacgag atggattgac ctgaagctgt caggatctgc cataattctt
      901 cacctaggtg tggggcaaat ggggctagca attgaacgaa gcctttggcg tatgccacat
      961 aaagctcgtc ctctttattg gctgcattga caaaaatcat gagctgggca atagcagtat
     1021 tgaatttcat gccttcgatt tgttctgtga ctgccttaac agtctcatgg taagccttat
     1081 ctaaagctcc gctattttct gcaacaattt cctttgtcgt gatcaaacgg taaacacgat
     1141 ctaggaactt gcgtgctccc tcaaggcctt cttcagacca agcaatggac gcatcaagtg
     1201 gccccataaa catttcatac acacgcaggg tatctgctcc gtactgctcc accacatcgt
     1261 ctgggttgac aacgtttttc agtgatttag acatcttagc aggggcctgc tcaagctcct
     1321 cgcctgtttc catgtggaag aagctaccat cacgcttgtc aaccttatcc gttgcgacca
     1381 aggccccacg atggtcgcga tagctggttc ccaaaatcat gccttgatta aagagctttt
     1441 ggaagggctc cttggttggc actacaccca gatcatagag taccttgtgc cagaagcgtg
     1501 cataaagcag atgaagcact gcgtgctcag caccaccaat gtaaatatct actggcagcc
     1561 attgctttaa caggtcctta tcagctaatt gctcatcatt gtgtgggtca atatagcgaa
     1621 ggtaatacca gcttgagcca gcccactgtg gcatggtgtt ggtctcacga cgccctttga
     1681 ccccatcctc gcgggtcacc tcaagccagt cagtcaagtt agctagtggt gattctcctg
     1741 taccagatgg gcgaatatcc ttggtcactg gcaaaacaag tggtaggtcc tgctcaggaa
     1801 ccgctgtcga ggtaccgtcc tcccaatgaa tgattgggat tggctcaccc cagtagcgct
     1861 gacgactgaa cagccagtca cgtaggcgat aagagacctt ttcatgaccg acaccagtct
     1921 cctccagcca cgccaccatt ttagcaatgg cacaagcctt atcaagacca tctaggaagt
     1981 cagaattaat gtgaataccg tcctctgtgt aggcagcctc atcaacattg cccccttcaa
     2041 gcactggaat aatctcaaga ttgaattgct ttgcaaatgc ccagtcacgc tcatcatgcg
     2101 ctggcactgc catgatagca cctgtaccgt agcttgcaag cacataatcc gcaatccaga
     2161 taggcatttc tttgccattg accgggttga tcgcataggc tcctgtccag acacctgttt
     2221 tttccttggc aagatcggta cgagcaaggt cagatttgag gctcgcttgg cgtttgtact
     2281 cagcaacagc ctgcgcttgc tctgctgtag taatgctatc tactaaggcg tgttctggtg
     2341 ccaaaacagc ataggttgca ccaaacaggg tatcaggtcg tgtggtaaag acggtgaagt
     2401 ctttatcggt atctttgacc ttgaaggtta cattagcccc tgttgattta ccaatccagt
     2461 tgcgctgcat atccttgatc gactctggcc aatccacttc ctccagatct gctagcaagc
     2521 gctctgcgta ggctgtgatt ttgagcatcc attggcgcat gggcttacgg acaactggat
     2581 agcctccacg ctctgatgtg ccatcaggga gaacctcctc attcgcaata gctgttccca
     2641 gctcttcaac ccagttaaca ggcacctcag cttcataggc taggcctttt tcatacaatt
     2701 ttgtgaaaat ccactgtgtc catttgtagt aactaggatc agttgtattg atctcacgat
     2761 cccagtcata cgagaagcca agagcattga tctgacgttt aaagttggca atgttttctg
     2821 ctgtaaactc agcagggtca ttaccagtat ccatcgcgta ttgctcagca ggcagaccaa
     2881 aggcatccca gcccattggg tggaggacat tataaccctg tgcacgcttg aagcggctta
     2941 aaatatcagt tgcagtgtaa ccctcaggat gcccaacatg aagacctgca ccggaaggat
     3001 aaggaaacat atctaaagca taaaatttag gctttgaggc atctgtcccc gttttaaagg
     3061 tatgattatc agcccaaaag gcctgccact taggctcaat ggctttgtga ttgtaaaatg
     3121 tcatgtgaat tctcccatgt aaaaagtcta gtcttcttat tatagcacga tatcagactt
     3181 ttaggaatgg gcaagcaata ttgctgccac gacgtcggca tcacaaaaat gcatgtaacc
     3241 attttctagc tgcatgcatt tttttaatct atgttcagcg gttttgcatt gcaatatcac
     3301 cagtttctcg attgctattt gactatttca taacatattg ccaaaaaaac tatactgatg
     3361 ataaaaactc gctatgagaa agtgtaactg tcttcatgcg tttgtcacga cattgctaaa
     3421 gccctttaga ctagatagcg cgtctctgcg acgcataagc tcaagcctta cgagccaact
     3481 cataaaacag ccaaatatcc gctatcatct cacttggttt tagatctggt ctagctctag
     3541 ttttaagctc tcaaagaggt attgagcttg accaaggagt gcttgctaag ctactaaaaa
     3601 gccccttatc cttgctatca gataagaagc tcaatagagt ttataggaat gccaatgtcc
     3661 attagtaaaa tgctataaaa caatagttaa aggggagaga attgagaata gcttaatttt
     3721 tttggcgttt tggcatgact gttactaggc ctgcacttgt cataatcgca actgcagcag
     3781 cagtgaaaaa tggatttgca gtagcttcac ctgttgatgg tagctggcct gctggttttg
     3841 cggctggctt acttgctttt tgctttgcaa ccgagttcga tgcctgagga gtcttagaac
     3901 gaggctgtgc ctgatcctta aacttgtcag caagctcctg cttcaagcgc tcaatgttag
     3961 cttgaagatc agcattgcta cgatcctttt gctcaagcag gctttgaagc tccttaacct
     4021 tagcctcaag ctctgccttg tctgccttaa ccacatcaag ctcggctgtt ttttcagcta
     4081 attgcgcttc aaggtcagcc actctattat tagctgctgc tacctcttgc ccaagatttg
     4141 atactcttgc attagcttca gcaagtgcct gatctgccgc agctttttcc tttgcaagct
     4201 tatcaacatt agccttagca cctgccagct cctcttgaag tgttgtgatg ttagcattag
     4261 cagtttcaag gtcagtctct gctttaacct tgtcctgtgt taattgatca atctcagcaa
     4321 gcttctctgt gagctcacgc ttagcagagt tagtcaatcg acccagacta tcaacagcct
     4381 gacttaaacg atctgcttct gcttgagcta ctgagagttt gttggcaaga tcggcagatt
     4441 cactgagagc attatcacga tctgatgtta cctcttccag tttagtgctt aattctttag
     4501 aagtaagttt ttctctttct atatcggctt tcaattgagt tgtttctgct ttcaaagtag
     4561 cttcagagtc gatgcgagtc tttaaattcg ctaaaagttt tgaggaaata aaattacttc
     4621 ctttgatacc aatagaagaa ttaatctttt tatctaaact agggttgatt tacaactctt
     4681 catgttgttt gtttctcctt tttatttttc tctttcccag accaaagcac ctactcccta
     4741 agggaattac acgttggcct atagctatat tctacctaat tttattggat taacaaagct
     4801 cactaatttt acaccatgac aagttgtggc tattttaatg aaatataccg atatctatca
     4861 atagccgatg ttcccaagct tgttagttgt tttcgtttca aagatactac ccattcgttt
     4921 tcttagataa tggttaagct tggcgactat aacggttggc acaaatcgac taaagaaaaa
     4981 gatatcagca tgctcacagc ccctaatgac cgtatcagta ataatgacgt catagtcatg
     5041 ctgtagacac aaggcttcta tggttaattt atcaaaaatg gtaatctcaa aaaattcacc
     5101 aatgtatttt ttcaaaaagc ttcccgtact gccatgactt ctttctataa tcaagagctt
     5161 tggttttttc atcaattcac acatggttaa aaagaaattc tcccaggcta tcagcaagga
     5221 ataaaccaaa ttgttgagca aattagtagc aagctccata tccccgtcct taaatagcct
     5281 cttcacataa tcggtaaacc taaaataaac ataggtataa tgctccttaa agaaggccaa
     5341 gtaatccttt ttataatcgt aaatcagaaa gctttcacta atatcctcca ctcctaaaat
     5401 aacagtggca tgaagatatc tggcaacctc atatttattt ggcaatacaa tacctgtagc
     5461 tccctccatt tcactaagca aatctatcca gctcagcaag gactgaggac ccggaacctc
     5521 ctccttaacc ttatctacct gcaaggattt ttctaatacc aaatcatcat ctaaataatt
     5581 ggaaaacatt tctgacaaga caagctcatc aagcggtact gaaaatttaa gcacaaacaa
     5641 atgcgacagc tttttcatct cctgagaatc ctgtaacaac tccaatgaaa gactactcag
     5701 tgctttatgc ttcccaattt taaagccttt gaggtagcga atgagattaa ccgcacttaa
     5761 tagcttgagt tgacgaaaaa tcgcaaaatc aatcttaacc tctatcaaag atgccattaa
     5821 ttgaacaaat tgctcatggt ggttttcatt aagtagagaa gcaaaaggcc attcagaaaa
     5881 ggtatatgct tctgaaaaat acttgatgta aaacagtcta atattgtatt catctccaac
     5941 tacacgaatg ggcttagccg aaatgataat atcaaaatgc tcttttaaat agagattggt
     6001 tttacgaatc aagcgcttta aggttgacaa gctaataaaa agtgcctctg caagatcatc
     6061 taatgacgca aaatcatcaa aaaacaaggc cgacatcaac tgaagagaag gagactctag
     6121 caaggctctc cgataaacct cctttaagcc actttgatga ttgtaatgaa tatgaaattg
     6181 agaatccttg tagaacagct tgcctaaatc ttccataaaa acagaattcg tgatacacga
     6241 ttgcagcgtt aaaaccgaac aatccagcat ctgacaagca tctttataat ataatggatt
     6301 tttcgtttca cttaataaag taatcaactc aagctctcgc cactgctgct tggtaaagag
     6361 attctctata gacatggtat ctagctccta aatatactct tcctgattaa aaacttacca
     6421 caacacaaca ctatttcatt aactcttaat gtcggttgta gaacagtatt acatta
//
LOCUS       DARYYD010000084         6474 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.085, whole genome shotgun sequence.
ACCESSION   DARYYD010000084 DARYYD010000000
VERSION     DARYYD010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6474
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.085"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            48..323
                     /locus_tag="TV188_001821"
     CDS             48..323
                     /locus_tag="TV188_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VRR-NUC domain-containing protein"
                     /protein_id="HEL1535144.1"
                     /translation="MRTEKDIENYLKKKTKGLCLKFTSPGTIGVPDRIVVMNTGTFFV
                     EVKAPGKKPRPSQVAMHKKIKEAGQHVWVVDSYESVDMALKEMENWV"
     gene            320..1642
                     /locus_tag="TV188_001822"
     CDS             320..1642
                     /locus_tag="TV188_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEL1535145.1"
                     /translation="MRLHEYQEYAKTWIVEHPYCGLLLDMGLGKTLTTLSAIDEIQNI
                     FSEDHKILIVAPKKVAEETWPTEIEKWHFDFTYSKVLGSEGKRIEALETEADIYLINR
                     ENVTWLVEYYKTKWPFTFVVIDELSSFKSSKSKRFRALRKVRPKVQRLVGLTGTPAPN
                     SLIDLWPQIYLMDRGDRLETSQTRFKDKYFVPDKRNGPIVYSWTLRDGAEAEIYNKIE
                     DICVSMKAKDYLKLPPRTNNVVSVKLSNMKAYKQLEADLVLEFKDKEISAANSAVLVN
                     KLLQMANGAIYDADKTTVAIHDDKLDALEDIVEESQGQPILVFYQYQHDLERLKKRFP
                     QAEELTSVDKWNSGRIPILLCHPQSAGHGLNLQKGGHIIVWFGLTWSLEYYQQANARL
                     DRQGQTEPVIVHHIVAENTVDEKVLRILQGKEKNQNALLEAVKAQLGV"
     gene            1643..1810
                     /locus_tag="TV188_001823"
     CDS             1643..1810
                     /locus_tag="TV188_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535146.1"
                     /translation="MKKEYVVRIYTGREKNFEAKPQFEEKTFTRKADMLRFWDSCEAA
                     VKEKYTREWKK"
     gene            1807..1980
                     /locus_tag="TV188_001824"
     CDS             1807..1980
                     /locus_tag="TV188_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003051736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535147.1"
                     /translation="MTKQELIEEIEDEINDIDLLIDDYQYEIDELERDIDELDTQKDI
                     LKRKLDNLLESVE"
     gene            1980..2249
                     /locus_tag="TV188_001825"
     CDS             1980..2249
                     /locus_tag="TV188_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535148.1"
                     /translation="MTEQQMIDCLLYELAKKDKAIKNKSIIIAVLTAVLCLVSVLSIA
                     LQNHYEPQITGLQSQLRRTQYQLKRASEDRARQTKRIAELTGNGG"
     gene            2452..2868
                     /locus_tag="TV188_001826"
     CDS             2452..2868
                     /locus_tag="TV188_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF722 domain-containing protein"
                     /protein_id="HEL1535149.1"
                     /translation="MSRLSNAQLKAFDEWLFDYRFIDNKIALRKLELQTDMNTEVDKN
                     IGGGRANFVSKVTEDVVARWDSDRELKGLSNFKEAVIATLNLLDEELTDIFNLRWGVG
                     SSNTWEEIAYTRHLSRKSIYRKRERILEIFSKKIGM"
     gene            2958..3410
                     /locus_tag="TV188_001827"
     CDS             2958..3410
                     /locus_tag="TV188_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEL1535150.1"
                     /translation="MLGGDGKLSKLTLKQKRFADEYIISANATAAAIKAGYSKKTARS
                     IGQENLTKPDIKAYIDERLEKLESEKIATQEEVLQYLTSIMRGDQQEKTLISVGEFGQ
                     KIVDIDVGAKDRIKAAELLGKRYRLFTDKVEMDVSSDVTINVGEWDDD"
     gene            3400..4677
                     /locus_tag="TV188_001828"
     CDS             3400..4677
                     /locus_tag="TV188_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1535151.1"
                     /translation="MTTKQRPKINIVIKHPSKVFNKHIYDKLYNYSNFTEVHYGGASS
                     GKSHGVFQKIILKALNPKFKHPRKILVLRKVGATVRDSVFADIMSNLSYFGILDKCKI
                     NMSAFRITLPNGSEFIFKGMDNPEKIKSIKGISDVVMEEASEFTLDDYTQLTLRLRDK
                     KHLEKQIYLMFNPVSKVNWVYKAFFVKTPKNTVVYQTTYKDNRFLDDVTRENIEELAD
                     RNEAYYKIYALGQFATLDKLIFPKYDKQILNKDKLSHLSSFFGLDYGFINDPSAFLHV
                     KIDDANKKLYVIEEYVRKNLTNDKIANAIKDLGYAKEEIRGDSAEKKSNQELRNLGIP
                     RMIDVTKGPGTVMQGIQYLLQYDWVVDERCVKTIEELENYTWKKDKKTNEYINEPVDS
                     YNHCIDAIRYAVQDRIYQSADRSKRMKNAKYYF"
     gene            4693..6225
                     /locus_tag="TV188_001829"
     CDS             4693..6225
                     /locus_tag="TV188_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012560651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEL1535152.1"
                     /translation="MEEKQFLAGTRFNENANKQFIMLQEDFEAIDYESKLWIDQLKNY
                     ISRFKAEQLERLKELKRYYLGDNNIKYRPAKTDKYAADNRIASDFAKYITVFEQGYML
                     GVPVEYKNENKDLQAAIDLMSVRNNEDYHNVKIKTDLSIYGRAYELLTVEEIDDKKTE
                     VKLYQLPAEQTFVIYDDTYQRNSLMAVHFYDIDYGSGKRKQIIKVYTSDTIYTYEDYN
                     LETKGTCLKEHEEHFFKGVPVNEYANNEERTGAYESVLDNIDAYDLSQSELANFQQDS
                     VNALLVIAGNAYTGADENDYLDDGRLNPNGRLAISIGFKKAQVLILDDNPNPNGVKPQ
                     AYFLKKEYDTAGSEAYKNRLVADILRFTFTPDTQDMKFSGVQSGESMKYKLMASDNYR
                     EKQERLFKKGLMRRLRLAANIWAIKGNEATTYSLVNDTSIVFTPNLPQNDNEIVTAAQ
                     NLYGIVSDQTIFEILNTVTGVDAEAELERLKEEADKKQSLPEPRLVGDASGQEEPTAE
                     KP"
     gene            6185..>6474
                     /locus_tag="TV188_001830"
     CDS             6185..>6474
                     /locus_tag="TV188_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HEL1535153.1"
                     /translation="MLVVKKNQQQKSLNYWQKRQEDILSYLDRADLDVFSELQKLYNE
                     QAFELQKELFDFYTKYSEENKMTYQDVVKKLRHEDLSDYVANANKYRKQAEK"
BASE COUNT         2275 a         1048 c         1413 g         1738 t
ORIGIN      
        1 gttgaaaaaa aacgtaaccc tgacctttat tgaccaaagg aggaaagatg aggactgaaa
       61 aagatattga aaattatttg aaaaagaaaa caaaagggct gtgtttaaaa tttaccagtc
      121 cagggacgat aggagtacct gacagaattg ttgtcatgaa tacgggaacc ttttttgtag
      181 aggtcaaagc gccaggcaaa aaaccaagac ccagccaagt tgccatgcac aaaaaaataa
      241 aagaggctgg gcagcacgtt tgggttgttg actcctacga atcagtggac atggccttaa
      301 aagaaatgga gaactgggtg tgagactgca cgagtaccaa gaatacgcta agacatggat
      361 agtagagcac ccttattgcg gccttttact tgacatgggc cttggtaaaa cgctgacaac
      421 actatcggcg atagatgaga ttcaaaatat tttttccgag gatcataaga ttttaatcgt
      481 agcccctaaa aaagtggcgg aagaaacgtg gcctacggag attgagaaat ggcattttga
      541 tttcacctac tctaaagttt tggggagcga gggaaaacga attgaggcgt tagaaacaga
      601 agctgatatc tatttgatta atcgtgagaa tgttacttgg cttgttgaat actacaagac
      661 taaatggccg tttacctttg ttgttattga tgagctgtca agctttaagt ctagtaagtc
      721 aaaacggttt agggctttgc gaaaagttag accgaaagtc caacgccttg taggactaac
      781 aggaacccca gcgcctaaca gtttgattga tttgtggccg cagatttatc tgatggacag
      841 aggcgacagg cttgagacta gccagactcg atttaaagac aagtattttg ttcctgataa
      901 gcgtaatggt ccaatcgtgt atagctggac acttagggat ggtgcagaag cagaaatcta
      961 taacaagatt gaggatatct gtgtcagcat gaaagctaaa gactatctca agttaccgcc
     1021 gcgaaccaac aacgttgtat cagttaagtt atctaatatg aaagcttaca aacagcttga
     1081 agctgatttg gtgttggagt ttaaggataa ggaaatatct gcggctaact ctgcggtttt
     1141 ggtcaataaa ttactccaaa tggccaatgg cgctatctat gatgctgata aaacgacagt
     1201 tgctatacac gatgacaaac ttgacgcgct tgaggacata gtagaagaaa gccaaggcca
     1261 gccaatctta gttttttatc agtatcaaca tgatcttgaa agacttaaga aacgattccc
     1321 tcaggctgaa gagttgacgt cagttgacaa gtggaattct ggaagaatac caattcttct
     1381 gtgtcaccct caatcagctg ggcatgggct taatctacaa aaaggcgggc atattattgt
     1441 ttggtttggg ctaacgtgga gtcttgaata ttatcagcaa gctaatgcca gattagatag
     1501 acaagggcag acagaacccg ttattgtgca ccacattgtt gcagaaaata cagttgatga
     1561 aaaagtactt aggattttac aaggcaaaga aaaaaatcag aacgccttac ttgaagcagt
     1621 taaggcgcag ttaggggtct agatgaaaaa agaatatgtc gttagaatct acacgggtag
     1681 agaaaagaat tttgaggcaa aacctcagtt tgaagagaaa acctttacgc gaaaagcaga
     1741 catgttgagg ttttgggatt cttgcgaagc agcagttaaa gaaaaatata ctagggagtg
     1801 gaaaaaatga caaaacaaga actaattgaa gaaatagaag atgaaatcaa tgacatagat
     1861 cttttgattg acgattacca atacgaaatt gacgaattag aacgagatat agacgaatta
     1921 gatactcaaa aagatatttt gaagcgtaaa ttagataacc tgttagaaag cgtggaatga
     1981 tgactgaaca acagatgatt gattgcctgc tttatgagtt agcaaaaaaa gacaaagcaa
     2041 tcaaaaataa aagcatcatt atcgctgtac taacagctgt gctgtgtctc gtgtctgttt
     2101 taagcatcgc actgcaaaac cactacgaac cacaaattac aggtttacag tcacaattac
     2161 gcaggacgca gtatcagctt aagcgagcta gcgaggatag agctagacag acaaaacgga
     2221 ttgcagaatt gactggaaat gggggatgat tatgttgcta attgacgaag taaaaaaatg
     2281 tgaatcatct tatgagatat ttagtaaacc agttgtacta agtagagatt tatatatttt
     2341 ttggaggata ggagatgagg atggacaata acacagcagc tgttttgaca ctgctaatac
     2401 tatttttacc ttttattatt ggaagtttta gagattaagc gaggtaacga gatgagtaga
     2461 ttatctaatg cacagctaaa ggcttttgat gaatggctgt ttgattatcg ctttattgat
     2521 aacaagattg cacttcgaaa acttgagcta caaactgaca tgaatacaga agtagataaa
     2581 aatatcggtg gaggaagagc aaattttgtt tcaaaagtta ctgaggatgt ggttgcaagg
     2641 tgggattcag atagggaact aaagggtcta tccaatttca aagaagcagt tattgcaacg
     2701 ctaaatcttt tggatgaaga actaactgat atttttaatc ttaggtgggg cgtcggttca
     2761 agtaacactt gggaagaaat tgcctataca agacatctgt cgcgtaagtc tatttaccgc
     2821 aaaagagagc ggattctaga aatattttcc aaaaaaatag gaatgtgaca caaaaatgta
     2881 tggaattgtc atctttttga tgataaattg gtagtatgag tttgaaggta aggcagatag
     2941 tgtcttgcct ttttgctatg cttggaggtg atggaaaatt gagtaaatta accctaaaac
     3001 agaagcgttt tgcagatgag tacatcatct cagctaacgc gacagcagcg gctattaaag
     3061 cagggtatag taaaaagaca gcaaggtcaa taggtcaaga aaacttgacc aaacctgaca
     3121 ttaaagctta tatagacgag cggcttgaaa aacttgaatc tgaaaagatt gctacgcaag
     3181 aagaagtcct acaatatctc acttcaatta tgcgaggaga ccaacaagaa aagacgctca
     3241 ttagcgttgg agagtttggc cagaagatag ttgacatcga tgttggtgcc aaggatagaa
     3301 tcaaggcagc tgagctacta ggcaaacggt acaggttatt tactgacaag gttgaaatgg
     3361 atgtcagctc agatgtaacc attaacgtag gtgagtggga tgacgactaa acagcgccct
     3421 aaaattaata tcgtgatcaa gcatcctagc aaagttttta acaaacatat ctacgacaaa
     3481 ctttacaact atagcaactt cacggaagtt cattatggtg gggcgtctag cggaaagtct
     3541 cacggtgttt ttcaaaagat aattttaaaa gcacttaacc ccaaattcaa acatcccaga
     3601 aagatattag ttctcagaaa agtcggtgca accgttagag actctgtatt tgctgatatc
     3661 atgtctaatt tgtcgtattt cggcatcttg gataaatgta agataaatat gtcggctttt
     3721 agaataacgc tcccgaatgg ctcggaattc atttttaagg gtatggataa ccctgagaag
     3781 attaagtcaa ttaaggggat atctgatgtc gtcatggaag aagctagtga atttacgctt
     3841 gatgattata cgcagttgac tttgcgttta agagataaga aacatctaga gaagcaaata
     3901 tacttgatgt ttaaccctgt gtcaaaagta aactgggttt ataaagcctt cttcgttaag
     3961 acacctaaga atacagttgt ctatcaaaca acttataaag acaaccgctt cttagatgat
     4021 gtcacgagag aaaatattga ggaactagcc gataggaatg aagcttacta caaaatatat
     4081 gctcttggcc agtttgctac acttgataaa ctaatttttc ccaaatatga caagcaaata
     4141 ttaaacaaag acaagttatc acacttgtct tctttttttg gtttggacta tgggtttatc
     4201 aatgaccctt cggcattttt gcatgttaaa atcgatgacg caaacaagaa gttatacgtc
     4261 atagaggaat atgtcagaaa gaatttgacc aatgacaaaa tagcaaatgc tataaaggac
     4321 ctcggctatg ccaaagaaga aatcagagga gattcggctg aaaagaaatc taaccaagag
     4381 ctgaggaatt taggtattcc tagaatgatt gatgttacca aagggcctgg aaccgttatg
     4441 caaggaattc agtacctgct tcagtatgat tgggttgttg atgaaaggtg tgtcaagact
     4501 attgaagaac tcgaaaatta cacttggaag aaagacaaga aaactaatga gtatatcaac
     4561 gaaccagttg acagttataa ccactgcatt gacgccataa gatatgccgt acaagacaga
     4621 atataccagt cggcggatag aagtaagcgc atgaaaaatg ctaaatatta tttttaggaa
     4681 tgaggtgaga ctttggaaga aaaacaattt ttagcaggaa ctcgttttaa tgagaatgct
     4741 aataagcaat ttattatgct gcaagaagac tttgaagcaa ttgactatga atcaaaactt
     4801 tggatagatc aacttaagaa ttacatttca aggtttaaag cagaacaatt agagcgtttg
     4861 aaagagttaa agcgatacta tcttggggat aataacatca agtatagacc tgctaaaaca
     4921 gataaatacg cagcggataa tcgtattgca agtgattttg ctaaatatat tacggtattt
     4981 gagcaaggtt atatgcttgg tgttcccgtt gagtacaaaa atgaaaataa agacctccag
     5041 gcggctattg accttatgtc ggtcagaaac aatgaggact accacaacgt caaaataaaa
     5101 acagatttat caatttatgg aagagcctac gagctgttaa ctgttgagga aatagatgac
     5161 aaaaaaaccg aagtaaaact ctaccagctc ccagccgagc aaacttttgt tatctatgat
     5221 gatacatacc agcgaaattc gttgatggcc gttcattttt acgacataga ttatggctca
     5281 ggtaaacgca aacagattat caaagtatat acttccgaca caatttacac ctacgaagac
     5341 tataatctcg aaacaaaagg tacgtgctta aaagagcatg aagaacattt ttttaaaggt
     5401 gtaccagtca atgaatatgc taataatgag gagcgtacag gggcttatga gtctgtactt
     5461 gataatattg atgcctatga tttatctcag tccgagcttg ctaattttca acaagattca
     5521 gtcaatgcgt tgcttgtaat agctggtaat gcttacacag gggctgatga gaatgactac
     5581 ttagatgacg gacgattaaa tcctaatggt cgcttagcga tctcaattgg gtttaaaaaa
     5641 gcccaagtgt taattttaga cgataatcct aatccaaatg gcgttaaacc acaagcgtac
     5701 tttctcaaaa aagagtatga taccgccggt agcgaagcct acaaaaatag actagttgca
     5761 gacattttga ggtttacttt tacgccagat acacaagata tgaaattttc aggagttcaa
     5821 tctggtgaat caatgaagta taagcttatg gcttctgaca actatcgcga gaagcaagag
     5881 aggttgttca aaaaaggctt aatgcggcgc ttacgcttag cagctaatat ctgggccatc
     5941 aaagggaatg aagcaactac atatagcctt gtaaatgata cgagtatagt tttcacacct
     6001 aatcttcctc aaaacgataa tgaaattgtt acagctgcac aaaatcttta tggcattgtt
     6061 agcgatcaga ctatctttga aatcttaaac actgtcacag gagtagacgc tgaagcagag
     6121 cttgaacgtt tgaaagaaga agctgataaa aagcaatctt taccggagcc tagattggta
     6181 ggtgatgcta gtggtcaaga agaaccaaca gcagaaaagc cttaattact ggcaaaagcg
     6241 tcaagaagat attctaagtt atttagacag agctgattta gatgtctttt cagaactgca
     6301 gaagttatat aatgaacagg cttttgagtt acaaaaggaa ttgtttgatt tttatactaa
     6361 gtattctgaa gagaacaaaa tgacttatca ggatgtcgtt aaaaagctac gtcatgaaga
     6421 tttatcagat tacgtagcta atgctaacaa gtatcgcaaa caagctgaga aaga
//
LOCUS       DARYYD010000085         6368 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.086, whole genome shotgun sequence.
ACCESSION   DARYYD010000085 DARYYD010000000
VERSION     DARYYD010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6368
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.086"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            62..1180
                     /locus_tag="TV188_001831"
     CDS             62..1180
                     /locus_tag="TV188_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_192934711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronoglucosaminidase"
                     /protein_id="HEL1535154.1"
                     /translation="MSKEVASARIQHRGMTKQEWESSSDILMEREIGIDMTTGYPKVG
                     DGKNKFKDLKDLRGPMGPQGPSGERGLTGPIGPRGPAGKPGTTDYNQLQNKPNLDAFA
                     QKKETNSKITKLESSKADKSAVYSKAESKIELDKKLSLTGGIVTGQLQFKPNKSGIKP
                     SSSVGGAINIDMSKSEGAGVVVYSNNDTSDGPLMSLRTGKETFNKSALFVDYKGTTNA
                     VNIVMRQPTTPNFSSALNITSDNENGSAMQLRGSEKALGTLKITHENPNVEAKYDENA
                     TALSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLSDDKFYVKSDGGFYAKET
                     SQIDGNLKLKDPTANDHAATKAYVDKAISELKKLILKK"
     gene            1195..3081
                     /locus_tag="TV188_001832"
     CDS             1195..3081
                     /locus_tag="TV188_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gp58-like family protein"
                     /protein_id="HEL1535155.1"
                     /translation="MSRDPTLILDESNLVIGKDGRVHYTFTAEDDNPKVRLASKCLGT
                     AHFNQLMIERGDQATSYVAPVVVEGTGNPTGLFKDLKEISLELTDTANSQLWSKIKLT
                     NRGMLQEYYDGKIKTEIVNSARGVATRISEDTDKKLALINDTIDGIRREYRDADRKLS
                     ASYQAGIEGLKATMANDKIGLQAEIKASAQGLSQKYDDELRKLSAKITTTSSGTTEAY
                     ESKLAGLRAEFTRSNQGTRTELESQISGLRAVQQSTASQISQEIRDREGAVSRVQQSL
                     ESYQRRMQDAEENYSSLTHTVRGLQSDVGSPTGKIQSRLTQLAGQIEQRVTRDGVMSI
                     ISGAGDSIKLAIQKAGGINAKMSGNEIISAINLNSYGVTIAGKHIALDGNTTVNGTFT
                     TKIAEAIKIRADQIIAGTIDAARIRVINLNASSIVGLDANFIKAKIGYAITDLLEGKV
                     IKARNGAMLIDLNTAKMDFNSDATINFNSKNNALVRKDGTHTAFVHFSNATPKGYTGS
                     ALYASIGITSSGDGVNSASSGRFAGLRSFRYATGYNHTAAVDQTELYGDNVLIADDFS
                     INRGFKFRPDKMQKMLDMNDLYAAVVALGRCWGHLANVGWNTAHSNFTSAVTNELNNH
                     INKI"
     gene            3093..3530
                     /locus_tag="TV188_001833"
     CDS             3093..3530
                     /locus_tag="TV188_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011106643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1535156.1"
                     /translation="MDLTLKNKDLNTLYSVLDKIKVTNMRANRGRAKLLAKVVDKFKE
                     YAKDEGDLIDLYAQKDKDGKFVIDEHKNIKLADPAKLDEFNGLLNELADEEIVIKGGE
                     YSKRFIDFLNFLEECEDEFTSSEIILIDNILEQFEESKKGEKP"
     gene            3527..4138
                     /locus_tag="TV188_001834"
     CDS             3527..4138
                     /locus_tag="TV188_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1535157.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHIIITAEDGSVISQPIKQGLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKISQETAKTAKTAQTAAGLAKVS
                     AERTQRMINLQTIHVLTSGGKVEPDIYKGMLELIEPAKQGEYQAYDVFTVVDESHEDQ
                     AGEGNLVFVHVNEPFTYDKQTLKELEEEDKVTVIKYADLVKQD"
     gene            4150..4422
                     /locus_tag="TV188_001835"
     CDS             4150..4422
                     /locus_tag="TV188_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535158.1"
                     /translation="MATELIFGLGGFILAIVTTYNIFNAKSIKHATDITLLQSEVEHL
                     KIVTRQNARRLEEHDEQNKTLITMTEQIKNLNREVRELKDIMRGEA"
     gene            4419..4646
                     /locus_tag="TV188_001836"
     CDS             4419..4646
                     /locus_tag="TV188_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEL1535159.1"
                     /translation="MINLKLRLQNKVTLMAILGAIFLLAQQLGIKLPSNIADIANTAV
                     TLLVLLGVVTDPTTKGLSDSEQALTYHEPKQ"
     gene            4763..6097
                     /locus_tag="TV188_001837"
     CDS             4763..6097
                     /locus_tag="TV188_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysin"
                     /protein_id="HEL1535160.1"
                     /translation="MATYQEYKSRSNGNAYDIDGSLGAQCWDGYADYCKYLGLPYANC
                     TNTGYARDIWEQRHKNGILNYFDEVETMQAGDVAIFMVVAGVTPYSHVAIFDSDAGSG
                     YGWFLGQNQGGANGAYNLVKIPYSTTYPTAFRPKVFKNAVTVIGNIGLNKGDYFIDVS
                     AYQQADLTATCQQAGTTKTIIKVSESLAWLSDRHQQQANTSDPIGYYHFGRFGGDSNL
                     AQREADLFLSNLPTKKVSYLVIDYEDSASADKEANTNAVIAFMDKIANAGYKPVYYSY
                     KPFTLNNIDYQQIIAKYPNSIWIAGYPDYEVRTEPLWEFFPSMDGVRWWQFTSVGVAG
                     GLDKNIVLLADDSSKVDIPKIDKPQSQLTFNQKLDTNTKLDNSNVPYYEATLSTDYYV
                     ESKPNASSADKEFIKAGTRVRVYEKVNGWSRINASQSDQWVEDKYLSNATQV"
BASE COUNT         2139 a         1185 c         1417 g         1627 t
ORIGIN      
        1 atttaatttt ggactgggcg gaaaacccag atattatttt tgacggaaac ggaggtattt
       61 aatgtcaaaa gaagttgcat cagcaaggat acagcataga ggcatgacca aacaagagtg
      121 ggaatcaagc tccgatatct taatggagcg agaaattgga attgatatga ctacgggtta
      181 cccaaaagtt ggtgatggca aaaataagtt caaggactta aaagacttgc gcggccctat
      241 gggacctcaa ggtccttcag gagaaagagg cctaactggc ccaattggtc ctcggggccc
      301 tgctggcaag cctggaacga cagattataa tcaactccaa aataaaccaa atctagatgc
      361 gtttgcacaa aaaaaagaaa ctaatagtaa aatcaccaaa ttagaatcaa gcaaagcaga
      421 taaaagcgct gtttactcaa aagcagagtc aaaaatagag ctagacaaaa aattgagttt
      481 gacaggcggc atagtgacag gacaactaca gtttaaacct aataaaagtg gtattaaacc
      541 ctcatcttcc gtaggaggag cgattaacat tgatatgtct aaatcggaag gtgctggtgt
      601 tgttgtctat tctaacaatg ataccagtga tgggccgtta atgagcttgc ggacgggtaa
      661 agagaccttc aataaatcag cgctttttgt cgattataag ggaacaacaa atgccgttaa
      721 tattgtgatg cgtcagccaa ccacccccaa tttttcatcg gcgcttaata ttactagcga
      781 caatgaaaat ggtagtgcaa tgcagctacg agggtcagaa aaagcgctag gaacgctcaa
      841 aatcacacac gaaaacccaa acgttgaggc aaaatacgat gaaaacgcta cagcgttatc
      901 tattgatatc gttaaaaaac agaaaggcgg aaaaggtact gctgctcaag gaatctacat
      961 taactcaaca tcaggcacga cagggaagtt gcttaggatt agaaacctta gtgatgataa
     1021 gttctacgtc aagtctgacg gtggttttta tgccaaggaa acttcgcaga ttgatggcaa
     1081 cctgaaactc aaggacccca cagcgaatga tcatgcggca accaaagctt atgtagataa
     1141 agcaatttct gagttaaaaa aactcatact aaaaaaatag attaaggagg ataaatgagc
     1201 agagacccaa cacttatttt agacgagtca aacctcgtta ttggtaagga tggacgtgtg
     1261 cattacacat ttaccgcaga ggacgacaac ccaaaagtca gactagctag caagtgtcta
     1321 ggcacagcgc attttaatca gctcatgatt gagcgaggag accaagctac tagctatgtt
     1381 gcgccagtag tagttgaggg tacaggtaat ccgactggac tatttaaaga cctcaaagag
     1441 attagcctag agctgacaga tactgctaat tcccagcttt ggtcaaaaat caagctgact
     1501 aaccgtggta tgttgcagga atactacgac ggtaagatca agaccgagat agtcaactcc
     1561 gccagaggtg tcgctacacg tatcagcgag gatactgata aaaagctagc gctcatcaat
     1621 gacaccattg atggtatcag gcgtgagtat cgagatgctg ataggaagct atccgcaagc
     1681 tatcaggcag gcatcgaggg gctaaaagcc acaatggcca atgataaaat cggtttacaa
     1741 gctgagatta aagcctcagc acaagggcta tcgcaaaagt atgatgatga gttgcgcaag
     1801 ctatcggcta agatcacaac aacctcaagc ggcactacag aggcctacga gagtaagctt
     1861 gcgggcttac gtgctgagtt tactcgctca aatcaaggca cgaggacaga gctcgagtca
     1921 caaattagcg ggctaagagc ggtacagcag tcaacagcta gccaaatctc tcaagagatt
     1981 agagaccgtg aaggtgctgt cagtcgtgtg cagcagagtt tggagagtta ccaaaggcgg
     2041 atgcaggacg cagaagaaaa ctatagtagc ttgacccata cggttagagg gctacagagc
     2101 gacgttggat ctccgactgg taaaatccaa tcgcgcctta ctcaactagc aggacaaatt
     2161 gagcagcggg ttactagaga tggtgtcatg agtattatta gtggcgctgg agacagcatt
     2221 aaattagcta tccaaaaggc tggcggcatt aatgccaaaa tgtctggtaa tgagattatc
     2281 tcagcaatta acctcaactc ctacggagta acaatcgcag gtaaacacat cgctctcgat
     2341 ggcaatacga ctgtcaacgg cacctttacc acaaagatag cagaggctat caagattagg
     2401 gctgatcaga ttattgcagg cacgattgac gctgctagga ttagagtgat taaccttaac
     2461 gcaagtagta tcgttggttt agacgctaac tttatcaaag ctaaaattgg ctatgctatc
     2521 actgatttgc tcgagggtaa ggtcattaag gctcgtaatg gagcgatgct tatcgactta
     2581 aatacagcta agatggactt taatagcgat gccacaatta attttaatag caaaaacaat
     2641 gccttagtac gtaaagatgg cacacatact gcctttgtac attttagtaa tgcgacgccc
     2701 aaaggttata cagggtcagc gttgtatgca tcgatcggga taacctcatc tggtgacggt
     2761 gttaactcgg cttcttccgg tcgttttgca gggctaaggt catttaggta cgctacggga
     2821 tataatcata ctgctgcagt cgaccaaacc gagctatacg gtgataatgt cttgattgca
     2881 gatgacttta gcatcaatcg aggatttaaa tttagaccag acaagatgca aaaaatgctt
     2941 gacatgaacg acttgtatgc ggctgtagta gccttaggcc gctgttgggg gcacttggct
     3001 aacgtcggct ggaatactgc tcatagcaat tttacaagtg cggtcactaa cgagttaaat
     3061 aatcatatca acaaaattta ataggagaaa caatggattt aacgcttaaa aacaaagatt
     3121 taaacacact atatagtgta ctagacaaaa tcaaagtcac gaacatgcga gcaaaccgcg
     3181 gacgtgctaa gctactcgca aaagtagtcg ataaattcaa agagtacgcc aaggatgagg
     3241 gtgaccttat tgatctgtat gctcaaaaag acaaagatgg caagtttgtc attgatgagc
     3301 acaaaaacat caagctagca gaccccgcta aactcgacga gttcaacggc ctactcaacg
     3361 agctagctga tgaagaaatt gtgattaaag ggggtgagta ctccaagcga tttattgact
     3421 ttttaaactt tttagaagag tgtgaagatg aatttacatc atctgaaatc attcttatcg
     3481 acaacatttt ggaacaattt gaagaaagta aaaaaggaga aaaaccatga gaaattggaa
     3541 agtgacagga aaatacccac aatttgacag cacaggagca gtcgcaagca cacatattat
     3601 tatcactgct gaggatggct cagtcatctc tcaaccaatc aagcagggct taacttcaac
     3661 taatgacaca gagattatca aagctacttt ggaagaattt aaaaaatctg aatacgtcga
     3721 aatcgctatg ggcgaagccg tgcaaaaagt agacgacctt gaaaaaatct cacaggaaac
     3781 cgctaagacc gctaaaacag cccaaacagc cgcaggatta gctaaggtgt ccgcagagcg
     3841 tacacagcgg atgattaact tgcaaaccat ccacgtattg acaagtggtg ggaaagttga
     3901 acccgatatc tacaaaggta tgttagagct tattgaacct gctaaacaag gcgagtatca
     3961 ggcttatgac gtgtttactg ttgtagatga gtcgcacgaa gatcaagcgg gagaaggtaa
     4021 tcttgtcttt gtacacgtta acgagccgtt tacttatgac aaacagacgc ttaaagagct
     4081 agaggaagag gataaagtca cagtcattaa gtatgcggac ttagttaagc aggattagcg
     4141 aggtaagcta tggcaacaga gttgatattt ggtcttggtg gctttatttt agctatcgtc
     4201 acgacttaca atatttttaa tgcaaaatcc atcaagcatg cgacagatat tactttgttg
     4261 cagtctgaag tagagcattt aaaaattgtt acacgccaaa atgctcggcg tcttgaggag
     4321 catgatgagc aaaacaaaac gctcatcaca atgacagagc aaattaaaaa cctcaatcgt
     4381 gaggtaagag aacttaaaga tattatgaga ggtgaagcat gatcaattta aaattacgac
     4441 tacaaaacaa agtaaccttg atggctattt taggagctat ctttttactg gcacagcaat
     4501 taggtattaa actaccatca aacatcgcgg atattgcaaa cacagctgta acgcttttgg
     4561 tattgctcgg tgttgtcaca gatccaacca cgaaaggcct gtcagacagt gagcaagctt
     4621 tgacttacca cgaaccaaaa caataggagg ggacatgcgg gcaatcacac gattagcatt
     4681 agttatagca atagcaatac tgtatgtgcc attatctgtt gttgctttga ttttaagccc
     4741 atttttagat aaggagggat aaatggctac atatcaggaa tataaaagtc gttcaaatgg
     4801 caatgcttac gatattgatg gatcgcttgg tgcgcaatgt tgggatggct acgcagacta
     4861 ctgtaagtat ctaggactgc catacgcaaa ctgtacaaat acaggatatg caagggatat
     4921 atgggaacaa cgtcacaaaa atggtatttt aaactacttt gacgaagtag agactatgca
     4981 agctggagat gtcgcaattt ttatggtagt tgcaggtgtt acaccgtata gccatgtggc
     5041 tatttttgat agtgatgcag gtagtggata cggatggttt ttaggtcaaa accagggtgg
     5101 agcaaacgga gcatataatt tagtaaaaat accatattca acgacttatc ctactgcatt
     5161 tagaccaaaa gtttttaaaa atgcagttac tgttataggt aatataggac taaataaagg
     5221 cgattatttt attgatgtat cagcttatca acaagcagac ttaaccgcta cttgtcagca
     5281 agctggcact actaaaacga ttatcaaagt atccgagtca ctcgcttggc tgtctgatag
     5341 gcatcagcaa caagctaata ctagtgaccc tattggttat tatcactttg gacgatttgg
     5401 aggagatagc aacttagcgc aacgagaagc agatttattt ctgtccaatt taccaaccaa
     5461 aaaagtctct tacttagtca ttgattatga agactctgca agtgccgaca aagaagctaa
     5521 cactaatgca gttattgcgt ttatggataa aattgcaaac gctggatata agcctgttta
     5581 ttacagctat aaaccattta cgcttaataa tattgattat cagcaaatta tcgctaagta
     5641 cccaaacagc atttggatag ctggttatcc agactacgaa gtacgaacag agccactttg
     5701 ggagttcttc ccttcaatgg atggtgtgcg ctggtggcag ttcacaagtg taggagtagc
     5761 aggtggttta gataaaaata ttgtattatt agcagatgat agtagcaaag tggatatacc
     5821 taagattgac aaaccacaaa gccagcttac ttttaatcaa aagctagata ctaacactaa
     5881 attagacaac tcgaatgtac cttactacga agcaaccctt agcacagact attatgtaga
     5941 gtctaagcca aacgcaagta gcgctgataa agaatttatc aaggcaggaa ctcgtgtaag
     6001 agtctatgaa aaagtgaatg gatggtcacg tattaacgct tctcagtctg accagtgggt
     6061 cgaagataag tatttatcta atgcaacaca agtataaaat aggaggtaaa gctcctttag
     6121 ataagacaaa tgccctcgct tttgcggggg ctgtttttgt tataaagatt ttaattgtta
     6181 tttaagcatt ttcgttgatt tttttctttt ttgtgctaaa atattttgtg atttcttatt
     6241 attaaagaag aatagggtac acttataagt gagaaaaatt gtaaatgtta attttaaaaa
     6301 gtttttaact tcatcttttc tattgtgggt atttatatca gctataattc caacgtgtta
     6361 cgcgtatg
//
LOCUS       DARYYD010000086         6324 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.087, whole genome shotgun sequence.
ACCESSION   DARYYD010000086 DARYYD010000000
VERSION     DARYYD010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6324
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.087"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..183
                     /locus_tag="TV188_001838"
     CDS             <1..183
                     /locus_tag="TV188_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1634 family transposase"
                     /protein_id="HEL1535161.1"
                     /translation="RIITALNSAKVTPLQDNYYRLQESLDMQELNRLLGIEWAKGIVK
                     FEELKHYAKNPYTTLK"
     gene            332..1582
                     /locus_tag="TV188_001839"
     CDS             332..1582
                     /locus_tag="TV188_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEL1535162.1"
                     /translation="MKELKCPHCHTLFTVNESDYSQILAQVRGQEFDKELAQRLESEM
                     KLQEARANNRFQEVLTKKEQAIQSLTNRLERIEQEQAYLRQQELAQKDKELLELHNQL
                     DKLELEQQSRLQSALTVVEKERDHLKNQLVLQEKESELSLASVRSDYEVQLKAVNEQV
                     EFYKNFKAQQSTKAIGESLELYAETEFNKVRSYAFPNASFTKDNQVSHRGSKGDYIYR
                     ELDNNGVEILSIMFEMKNEVDTTKTKHKNSDFFKELDKDRREKNCEYAVLVTMLEADN
                     DYYNAGIVDVSHDYDKMYVVRPQLFIHLIGLLRNAALNSLKYKQELALVREQHIDITH
                     FEEDLEHFKHAFAKNYQSASNNFKKAVDEIDKSIKRMEEVKRFLTTSENQLRLANNKL
                     DDVSVKKLTRNNPTMRDKFQAIKP"
     gene            1691..2572
                     /gene="truB"
                     /locus_tag="TV188_001840"
     CDS             1691..2572
                     /gene="truB"
                     /locus_tag="TV188_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002271102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEL1535163.1"
                     /translation="MINGIINLKKEAGMTSHDAVFKLRKLLQEKKIGHGGTLDPDVVG
                     VLPIAVGKATRVIEYMTEAGKTYEGEVTLGYSTTTEDASGEIVDQTVVPLSLTEAMVD
                     EAMTQFIGQMTQIPPMYSAVKVNGRKLYDYARAGEAVERPKRQVTIDQFERTSPLTFA
                     GGLCRFSFRVSCSKGTYIRTLAVDLGRMLGYASHMSWLVRTASSGLSLDQSYTLSEIA
                     ELLDKKDMSFLLPIEYGVSDLARVVVNDWELRELSFGRKIALSCEENLLAAFYQDSLI
                     AILEKQEGLYKPRKVFI"
     gene            2586..3518
                     /locus_tag="TV188_001841"
     CDS             2586..3518
                     /locus_tag="TV188_001841"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEL1535164.1"
                     /translation="MDIQHIKSYQEIDESADTVLVLGYFDGLHRGHKALFDKAKEISR
                     QESLKIVTLTFHESPQLAFTRFSPDFLRHITYPEKRYEKFAEYGVDKLYLLDFTTSFS
                     KLSSDDFIDHYIGRLRVRHIVVGFDYHFGCDHADSHYLAKRIKGTVYSISEVKEDQIK
                     ISSTRIRSLITAGDVAKANQLLGYELSTRGMVVHGDARGRTIGFPTANLAPIDRTYLP
                     ADGVYVTDVLVRGKRYRSMTSIGKNITFGGKELRLEANIFDFNEDIYGETLEIIWLDR
                     IREMNKFSDVSTFISQLKQDKEAAINWKKDSQGY"
     gene            3561..3965
                     /locus_tag="TV188_001842"
     CDS             3561..3965
                     /locus_tag="TV188_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEL1535165.1"
                     /translation="MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLA
                     ILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLIDLIAKNPSLLRRPIIMDSKRMQ
                     IGFNEDEIRAFLPRDYRKQELRQATIKAEIEG"
     gene            3967..4245
                     /locus_tag="TV188_001843"
     CDS             3967..4245
                     /locus_tag="TV188_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEL1535166.1"
                     /translation="MSDHYHYPLDVSWSTEEITSVLHFLNQVELAYEAKVGAEELLKS
                     YAAYKEIVRSKSQEKQIDREFQQASGYSTYQAVKKAREIEKGFFSLGR"
     gene            4235..5011
                     /locus_tag="TV188_001844"
     CDS             4235..5011
                     /locus_tag="TV188_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEL1535167.1"
                     /translation="MEDKYAFAKTIIKEAGLLIKDRMKDSLAIEIKTQHDDLVTNVDQ
                     ETQDFLIAKIKQAYPSDHMIAEEGGICHAITDGKVWVLDPIDGTVNFIVQKANFAIMM
                     AYYENGVGKFSLIYDVMADQLFSGGGDFAVTLNDQVLASYQDKPLDRSLIGCNAGMLS
                     RNDYNLHQLIDQTLGVRVYGGAGICMTKVLRQQLMAYFSYIQPWDYAAAAIMGESLGY
                     VLLTLEGKQPDFQSRQKVMFVPKSKLATIQSLLKTNENTQ"
     gene            5028..>6324
                     /locus_tag="TV188_001845"
     CDS             5028..>6324
                     /locus_tag="TV188_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEL1535168.1"
                     /translation="MQLPNDFIEKYQQLLGSEAKAFFESFDQPAISAYRINPLKHQSV
                     CLDPPIPDTPWGYYGRVSGKSPNHVSGVVYSQEPAAQMVAQVASPAKGTRVLDLAAAP
                     GGKSTQLLAYLENTGLLVSNEISTKRSKALVENIERFGARNVIVTNESADRLAAVFPE
                     YFDTIVFDGPCSGEGMFRKDPNAVSYWHKDYPAACASLQRSILAEAIPMLKPGGQLIY
                     STCTWSPEENEEVVRWLLESYDFLELEHIPKINGMAEGIGMPQAARMYPHRFKGEGQF
                     VAKLKDTRSTISSSSYKSPRSNLTQEQLRLWQDFEKNHLNITLSGLLQVFGDRLYLLP
                     DGLPCLRSLKIARNGLELGTFKKKRFEPSYALGLALRPEEVSLSVEINEEDFVTYASG
                     NTITLPESYATDWYQLVINGNGLGFAKIVGRTLKNSFPKG"
BASE COUNT         1943 a         1164 c         1477 g         1740 t
ORIGIN      
        1 cgtatcatta ctgccttaaa cagtgccaag gtaacaccgt tacaagataa ctactacaga
       61 cttcaagaaa gccttgatat gcaggagtta aacagactgc taggaattga atgggcgaag
      121 ggaatcgtta agtttgaaga gctcaaacat tacgctaaaa atccatatac aacactaaaa
      181 taaatttaaa gaccagcaaa atcccttggg acacaagggg ttagctggtc tttacttgtt
      241 tttaagtgat aaagtcggga gtctggaaaa atcattttct aggctttttt tgctataatg
      301 gcagtgagat aattgcaaga atggagaaat catgaaagaa ctaaaatgtc ctcattgcca
      361 taccttattt acggtcaatg agtctgacta tagtcagatt ttagcacagg tacgaggtca
      421 agagtttgac aaggagttgg cacagcgctt agaaagtgag atgaagctgc aagaagcaag
      481 ggccaataac cgcttccaag aggtgcttac taaaaaggag caggctattc aaagcctgac
      541 caaccgcttg gagcgtattg agcaggaaca ggcctatttg aggcaacagg agctagccca
      601 aaaggataaa gagctcctag agcttcacaa tcagctagat aagctagagc ttgagcagca
      661 atcaaggctc cagtctgccc ttacagttgt tgaaaaggaa cgtgatcacc taaaaaatca
      721 gctcgtgctg caggaaaaag aaagcgaact ttctctagcc tctgtgcgca gtgattatga
      781 ggtgcagtta aaggctgtca atgagcaggt tgagttttac aagaatttta aagcgcagca
      841 gtcaactaaa gctattggag agagcttaga gctgtatgcc gaaaccgagt ttaacaaggt
      901 tcgcagctat gcctttccaa atgccagttt taccaaggac aatcaagtgt ctcatcgagg
      961 ctcaaagggt gattatattt accgagagct agacaataat ggtgttgaaa ttctctcaat
     1021 catgtttgaa atgaaaaatg aggttgacac gaccaagacc aagcataaaa atagtgattt
     1081 ctttaaggaa ttagataagg atcgccggga aaagaattgt gaatatgctg ttcttgttac
     1141 catgcttgaa gcagacaatg attattacaa tgcaggaatt gttgatgtca gtcatgacta
     1201 tgacaaaatg tatgtggttc ggcctcagct ctttattcat ctcatcggat tgctgcgtaa
     1261 cgctgctctt aatagcttaa aatataagca agaactggcg cttgtcaggg agcagcacat
     1321 tgatattaca cattttgagg aggacctaga gcattttaag catgcttttg ctaaaaacta
     1381 ccagtctgca agcaataact ttaaaaaagc cgttgatgaa attgataagt ccatcaagcg
     1441 tatggaggag gtcaagcgct ttctaacaac tagcgaaaat cagctgcgtt tagccaataa
     1501 caagctagat gatgtctctg tcaaaaaact aaccagaaat aatccaacca tgcgcgataa
     1561 gtttcaagca atcaagccct aggattatct cagtcaggct tattgataga ggctttgttg
     1621 cttgtcaaaa gccttgtgaa atggttataa tagataggct aatgatcaaa acaataaacg
     1681 aaagtaacac atgataaacg gaataatcaa tttaaaaaaa gaagcaggca tgacatcaca
     1741 tgacgctgtt tttaagctta gaaagctatt acaagaaaaa aagattgggc atggagggac
     1801 gcttgatcct gacgtggtcg gtgttttgcc tatagcagtg gggaaggcaa cgcgagttat
     1861 tgaatacatg acagaagcag gtaaaaccta tgagggagag gttactcttg gctattcaac
     1921 gacaacagag gatgctagtg gagagattgt tgaccaaaca gtagtgccct tgagtttgac
     1981 tgaagcgatg gttgatgagg caatgacaca atttattggt caaatgactc agattccacc
     2041 gatgtattct gcggttaagg ttaatgggcg caagctttat gattatgcac gagctggtga
     2101 agcagtcgag cgccctaaaa gacaggtaac gattgaccag tttgagcgga caagtccctt
     2161 gacctttgca ggtggtcttt gccgatttag ctttagggtg agctgtagca aggggactta
     2221 tattaggacc ttggcggttg atctaggaag aatgcttggc tatgcaagtc atatgtcttg
     2281 gctggttcgg acagcttctt cgggtttaag tttggatcag tcctatacct tgtcagagat
     2341 tgctgagctg ctggataaaa aggacatgag ctttttattg cctattgaat atggtgttag
     2401 tgatttagcc agagtagtcg ttaatgactg ggagctgaga gagctttcct ttggtagaaa
     2461 aatcgctcta tcatgtgagg aaaatctgtt agcggctttt tatcaggaca gcttgatcgc
     2521 tattttagaa aagcaagaag ggctttacaa gccaagaaag gtttttattt agagaagatt
     2581 gatatatgga tatacaacac attaaaagct atcaggagat tgatgaatca gctgataccg
     2641 ttttagtctt aggctacttt gatggtctgc accgaggtca caaggctcta tttgataagg
     2701 caaaggaaat atcacgtcag gaaagcctaa aaatagtcac cttgaccttc catgagtccc
     2761 ctcagctggc ctttacacgc ttttctcctg attttttacg acacattacc tatccagaaa
     2821 aaaggtatga aaaatttgct gagtatggtg ttgataagct ttatttgctt gattttacca
     2881 cgtcattttc aaaactatcc tctgatgatt tcattgacca ctatattggg cgtttaaggg
     2941 taaggcatat cgttgtaggc tttgattatc actttgggtg tgatcacgca gatagtcatt
     3001 acttagctaa acggataaaa ggaaccgttt atagcatttc agaggtcaaa gaagaccaga
     3061 tcaaaatctc atcaacacgt atcagaagtc tgattacagc aggagatgtc gctaaggcta
     3121 atcagctgct tggctatgag ctttcaacaa gaggaatggt tgtgcatggt gatgcgcgtg
     3181 ggcgaaccat tggttttccg actgccaatc ttgcacctat tgataggacc tatctgccag
     3241 ctgatggtgt ttacgtgaca gatgtgctgg ttagaggaaa gcgctatcgg tctatgacga
     3301 gtatcggcaa gaacattacc tttggtggta aagagctgcg attagaggca aatatttttg
     3361 attttaatga ggacatttat ggagaaactc ttgaaattat ttggctagat aggattcgtg
     3421 agatgaataa atttagtgat gttagcacct ttatcagcca actaaagcag gataaagaag
     3481 ctgccataaa ttggaaaaaa gatagccaag gctattaaat ttttgtataa taaggtaagc
     3541 acaattaaca gaggaaaagt atgattacct tatttctatc accaagctgt actagctgcc
     3601 gtaaggccag agcctggctc accaagcatg acgttgactt tcaagagcat aatattatta
     3661 ccagcccact tagtcgtgag gagctgttag cgatcctatc ctttactgaa aatggaacag
     3721 aggatattat ttcaacacga tcaaaggttt ttcaaaaatt ggatattgat attgatgagc
     3781 tgtctatcat ggatttgatt gatttgatcg caaagaaccc tagccttctt cgtaggccaa
     3841 tcattatgga tagtaagcgc atgcaaattg gctttaatga agatgagatt agggcatttt
     3901 tgccaaggga ttatcgtaag caagagctgc gccaagcaac cataaaggca gaaatcgagg
     3961 gataacatgt cagatcatta tcattaccca cttgatgtaa gctggagcac tgaagagata
     4021 acatcagtgc ttcatttttt aaatcaggta gagttagcct atgaggctaa ggtaggagca
     4081 gaggagctac tcaaaagcta tgctgcctac aaggagattg taagaagcaa atcacaggaa
     4141 aagcagattg accgcgaatt ccaacaagcc agtggctatt caacctatca agctgtcaaa
     4201 aaagccagag aaattgagaa aggattcttt tcccttggaa gataaatacg catttgctaa
     4261 aacgatcatc aaagaggctg gccttctgat taaggataga atgaaagata gcttagccat
     4321 tgaaatcaag acgcagcatg atgatttagt gaccaatgta gatcaagaga cgcaggattt
     4381 cttaattgct aaaatcaaac aggcctatcc tagtgaccat atgattgctg aggagggcgg
     4441 tatctgtcat gctattacag atggcaaggt ttgggtgctg gatcctattg atggtacggt
     4501 gaattttatt gtacagaaag ccaattttgc gatcatgatg gcttattatg agaatggcgt
     4561 cggaaaattt agtctcattt atgatgtcat ggcagatcag cttttttcag gtggaggaga
     4621 ttttgctgtt actttaaatg atcaagtcct agcatcttat caggataagc cgcttgatcg
     4681 tagcttaatt ggctgcaatg caggtatgct ttcaaggaac gattacaacc tgcaccagtt
     4741 gattgatcaa accctaggag tgagggttta tggcggtgca ggcatttgca tgactaaggt
     4801 gttaaggcag cagctaatgg cttatttctc ttatattcaa ccttgggatt atgcagcggc
     4861 agccattatg ggcgaaagcc ttggctatgt cctgttgacc ttggagggaa agcagccaga
     4921 ctttcagtct agacagaagg tgatgtttgt tcccaagtct aaactagcca ccattcaatc
     4981 tctgctgaaa acaaacgaga atacccaata agattaaaat gaaaagcatg caattaccaa
     5041 acgattttat tgaaaaatac caacagctgc taggttcaga agcaaaagct ttttttgaga
     5101 gctttgatca gcctgccatc agtgcctaca ggataaatcc cttaaagcac caatcggtct
     5161 gccttgatcc tcctattcct gatacaccat ggggttacta cggcagggta tcaggaaagt
     5221 ctcctaacca cgtgtcaggt gtggtgtatt cccaagagcc tgctgctcaa atggttgctc
     5281 aggtggcctc acctgccaag ggaactagag tgttggattt ggcagcagcg ccaggtggca
     5341 agtcaactca gttacttgcc tatctagaga atacaggact tttagtgagt aatgagattt
     5401 cgaccaaacg cagcaaggcc ttagttgaaa atatagagcg ctttggtgct agaaatgtta
     5461 ttgtgacaaa tgagtcagct gacagactgg ctgctgtttt tccagaatat tttgacacta
     5521 ttgtctttga cgggccttgc tctggtgagg gcatgtttcg caaggatcca aatgctgtta
     5581 gctattggca caaggattac ccagcagcat gtgctagcct gcaaagatcc attttagcag
     5641 aggcgatacc tatgctaaag ccaggtggtc agctgattta ttcgacctgc acctggtcgc
     5701 ctgaagaaaa tgaagaggtt gttcgctggc tactagaaag ttatgatttt cttgagctgg
     5761 agcatatccc taagatcaat ggtatggcag aggggatcgg tatgccacag gcagctagaa
     5821 tgtaccctca tcgctttaaa ggagagggac agtttgttgc taagttaaag gatactagat
     5881 caacgatttc ctcttcaagc tacaaatctc caaggtctaa cctcactcaa gagcagctga
     5941 ggctgtggca ggattttgaa aaaaatcatt tgaacataac cttgtctggc ctattacagg
     6001 tctttggtga tcgtttgtac ttgttaccag atggcttacc ctgtcttcga tcgcttaaaa
     6061 tagcaagaaa tggtctggaa ttaggcactt ttaagaaaaa acgctttgag ccttcctatg
     6121 ctctgggctt ggcattaaga cctgaagagg tcagcttatc tgttgagatt aacgaagagg
     6181 actttgtcac atacgcctca ggaaatacca ttaccttacc agaatcttat gctacagatt
     6241 ggtatcagct ggtcattaac ggaaatggtc tgggctttgc taaaatagtt ggtcgcaccc
     6301 ttaaaaatag cttccctaag ggct
//
LOCUS       DARYYD010000087         6321 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.088, whole genome shotgun sequence.
ACCESSION   DARYYD010000087 DARYYD010000000
VERSION     DARYYD010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6321
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.088"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(3..1337)
                     /gene="trmFO"
                     /locus_tag="TV188_001846"
     CDS             complement(3..1337)
                     /gene="trmFO"
                     /locus_tag="TV188_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEL1535169.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQHK
                     TTHFAELVCSNSFRGDSLTNAVGLLKEELRRLDSIIMRAGEAHRVPAGGAMAVDREGY
                     AKAVTAELENHPLIEIIREEVIDIPSDAITVIATGPLTSDSLAEKIHALNGGAGFYFY
                     DAAAPIVDKSTINMDRVYLKSRYDKGEAAYLNCPMTKEEFMAFHEALTTAEEAPLNAF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYKGPRDGDFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLEHAEFVRYGVMHRNSYMDSPKLLTQG
                     FQSRANHRLFFAGQMTGVEGYVESAASGLVAGINAARLFKEEEPLVFPNTTAIGSLPY
                     YITHADSKHFQPMNVNFGIIKELDGPRIRDKKERYEAIAKRALADLAAYLTV"
     gene            complement(1719..2432)
                     /locus_tag="TV188_001847"
     CDS             complement(1719..2432)
                     /locus_tag="TV188_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3307 domain-containing protein"
                     /protein_id="HEL1535170.1"
                     /translation="MQGLSDYLYQHPILVLLVICHFLSDYHLQSQVIADKKEEQLAYL
                     GLHLLGVAAPLFLVVMCIPKLWLTAILIFSSHAVIDYFKPKWARIIKLDRSWVFVLDQ
                     LLHLFIILALVARVNQAEIPDWLHARQLLLVLFMVLITKPVNIIFKLCFNKFQPASDK
                     PMDTIVGAGAAIGNLERIVMGVCMVLGQFASIGLVLTAKSIARYNKISESPAFAEYYL
                     IGSLFSVLSVFIAAWMCFF"
     gene            complement(2453..3100)
                     /locus_tag="TV188_001848"
     CDS             complement(2453..3100)
                     /locus_tag="TV188_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1535171.1"
                     /translation="MLYIAVIGDLVHSKQIQSRSLVQESLKACLDQLNHDFSSYIVSN
                     LSVTLGDEFQGLLTNDAPVFQLIDLINQAMTGYPVRFGIGQGTILTDINPDISIGADG
                     PAYWRAREAIHYIHQKNDYGNTQVAIRTDKEHKDLVLNSLLAAGEAIKASWRASQLEV
                     FHALLDLGIYEEQFDQQLIGDTLDLQSSALSKRLKSSSVKVYLRSRHAALTYLQE"
     gene            complement(3215..5347)
                     /gene="topA"
                     /locus_tag="TV188_001849"
     CDS             complement(3215..5347)
                     /gene="topA"
                     /locus_tag="TV188_001849"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEL1535172.1"
                     /translation="MVTKTATKSKQETKRSATKKKSAAAKKNLVIVESPAKAKTIEKY
                     LGRQYKVVASVGHIRDLKKSSMSIDFDNHYEPQYINIRGKGPLINALKKEAKNAKKVY
                     LASDPDREGEAISWHLSHILGLDPDDNNRVVFNEITKDAVKEAFEGPRKIDMDLVDSQ
                     QARRVLDRIVGYSISPILWKKVKKGLSAGRVQSVALKLIIDREHEIKAFVPEEYWSID
                     GLFKKGTKKFQASFYGLNGKKMKLNTNDDVKLVLSRLSSDDFMVSKVEKKERRRHAPL
                     PYTTSSLQQDAANKINFRTRKTMMVAQQLYEGISLGPNGTQGLITYMRTDSTRISPVA
                     QNDAAGFIVERFGSQYSKHGNRVKNATGAQDAHEAIRPSNVNHTPEAIAKFLDKDQLK
                     LYTLIWNRFVASQMTAAVFDTVKVNLEQNSVLFVANGSQMKFDGYMAVYNDSDKSKML
                     PEMTEGEVVKKVTLTPEQHFTQPPARYSEASLIKTLEENGVGRPSTYAPTLDVIQRRY
                     YVKLAAKRFEPTELGEIVNQLIVEFFPDIVDVKFTADMEDKLDQIEIGKEAWQNVIDQ
                     FYKPFVKELTKAETEIEKIQIKDEPAGFDCELCGHPMVVKLGRFGKFYACSNFPECHH
                     TKAITKEIGVSCPACQQGQVIERKTKRNRIFYGCDRYPECDFTSWDLPVGRSCPKSGD
                     YLVEKKIRGGKQVVCSNEVCDYKEEIVK"
     gene            complement(5448..6293)
                     /gene="dprA"
                     /locus_tag="TV188_001850"
     CDS             complement(5448..6293)
                     /gene="dprA"
                     /locus_tag="TV188_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEL1535173.1"
                     /translation="MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDMAVVSCC
                     KNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYPLALREIYNPPVLLFYQGDLSLL
                     EKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
                     AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVL
                     VVEAKQRSGSLITCQLAMEEGRDIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILS
                     EYHYS"
BASE COUNT         1897 a         1468 c         1175 g         1781 t
ORIGIN      
        1 gattataccg ttaaataagc tgccagatca gctaaggcac gtttagcgat agcttcatag
       61 cgttcctttt tatctctgat acgaggtccg tcaagctctt taataatacc aaaattgaca
      121 ttcattggtt gaaaatgctt gctgtccgcg tgtgtaatat aataaggcag gctgccaatt
      181 gctgttgtat ttggaaaaac aagtggctct tcttccttga atagccgagc agcattaatg
      241 ccagccacaa gtccagaagc tgctgactcg acatagccct ccacaccggt catctgacct
      301 gcaaagaaaa gcctgtgatt agcgcgtgat tggaagcctt gtgtcagaag ctttggtgaa
      361 tccatatagg aattacggtg catcacaccg taacgcacaa actcagcatg ctcaaggcct
      421 ggaatcattt ggaaaacccg cttttgctct ccccatttta aatgtgtctg aaagcccacg
      481 atattataaa ggctgcctgc agcattatcc tgacgcagct gcacaacagc atagggcgtc
      541 ttgaaatcac cgtcacgtgg tcccttgtaa tcatctggat attccaagcc aaccggcttc
      601 attggaccat aaagcatagt cttaatccca cgctttgcca taacctcaat tggcatacag
      661 ccttcaaaat acttttcctt ttcaaaagca tttaaaggag cttcctctgc tgttgtcaaa
      721 gcctcgtgaa aggccataaa ctcttccttg gtcattggac agttcagata agcagcttct
      781 cccttatcat atcgcgattt taaataaacc ctatccatgt taatggttga cttatcgaca
      841 attggagctg ctgcgtcgta aaaataaaag ccagcaccac catttaaggc atgtattttt
      901 tcagcaaggc tgtcactggt caaggggcca gttgcaatta ctgtaatagc atcgctagga
      961 atgtcaataa cctcctcacg aatgatttca atcagagggt gattttcaag ctcagctgta
     1021 acagccttgg catagccttc gcgatctaca gccattgctc ctccggcagg gacacgatgg
     1081 gcttcgccag cacgcataat aatcgaatcc agacgacgca gctcttcctt taaaagccct
     1141 actgcgttgg ttaagctgtc accacgaaaa gagttggagc aaaccaattc tgcaaaatgg
     1201 gtggttttgt gttgcggtgt tgccttgaca ccacgcatct catatagctt aacaggaata
     1261 ccacgcttag caatttgata agctgcctct gatccagcta gaccagcacc aataacatta
     1321 atataagatt gagacaatag accaatacct ctttggggac ttatccatca ctgattgccc
     1381 cgcaactctt tctttcaagt aattaccctg cctattataa cagaaataag agcaaagcaa
     1441 aagaaggagc tgaacagcct cagtctttta tataaaggag ataagcccgt acctgcacgc
     1501 tctccacaaa gctagctgct tcaagcattt tagctttcgc ccaataccag ctatccacat
     1561 atcttgttca ctgcagtagt tactggaagg ctttttaagg cttatttttc aaaatctagc
     1621 caaaaatatt tcaccggacc tcatcatctt gctggtagca gctaaacaag ccttttccag
     1681 taaaaaaaaa gcaagcgaaa gcctgccctt gttcttgttt agaaaaaaca catccatgct
     1741 gcgataaaga cacttaagac actaaacagc gatccaatca aataatattc agcaaaggct
     1801 gggctttcag agattttatt gtagcgagca atagacttag cggtaagcac cagtccgatt
     1861 gaagcaaatt gtcccaacac catacaaacg cccataacaa tacgctctaa attaccaata
     1921 gccgcacccg cccctacaat ggtatccatt ggtttatcac tagctggctg gaatttattg
     1981 aagcagagct taaagataat attgacaggc ttggtgatca aaaccataaa aagcactaac
     2041 aataactgcc gagcatgtaa ccaatcaggg atctcagcct gattaacacg agcgactaaa
     2101 gccagaataa tgaaaagatg caagagctgg tccaacacaa agacccacga ccgatcaagc
     2161 ttaatgatac gagcccattt tggcttaaaa taatcaataa ccgcatggct actaaaaata
     2221 aggatcgctg ttagccaaag cttaggtata cacatcacca ctagaaacaa tggagcagct
     2281 acccctaata agtgcagccc cagataagca agctgctcct ccttcttatc agcaataacc
     2341 tgactctgaa ggtgataatc tgataaaaaa tgacaaatca ctagcagcac taaaatagga
     2401 tgctgataaa ggtaatcaga taagccctgc ataggtggct cctttcctct ttttattctt
     2461 gtaggtaggt caaagctgca tggcgacttc taagataaac ctttacactg ctgcttttta
     2521 agcgctttga caaggcactt gattggaggt ccaatgtatc gccaatgagc tgttggtcaa
     2581 attgttcttc atagatccct aagtctaaaa gcgcatgaaa cacctctaat tgactagcac
     2641 gccagctagc ttttatcgcc tcaccagctg ctaaaaggct attgagcacc agatccttgt
     2701 gctccttatc agtccgtata gctacctggg tattgccata atcatttttt tgatgaatgt
     2761 aatgaatagc ctctctggca cgccaatagg ctggaccgtc agcaccaata ctaatatcag
     2821 ggttaatatc agtcaaaata gtcccctgtc caataccaaa cctaacaggg tagcctgtca
     2881 tggcttgatt aattaaatca atgagttgaa aaacaggcgc atcattagtc aacaagcctt
     2941 gaaattcatc acccagagtc acagataagt tagagacgat ataggaagaa aaatcatggt
     3001 tgagctgatc cagacaggcc tttaaggact cttgcaccaa agaacgcgac tgaatttgct
     3061 tagaatggac caaatcccca ataacagcga tatatagcat gattttccct ccttttatga
     3121 cttccattat aacagacaaa aaccaaaaag tccattataa tggaaaatca tctatatttc
     3181 cgttataatg gacctctgct aaaatagttc aaacctactt tacaatctct tctttatagt
     3241 cacagacttc attgctacac acaacctgct tacctccacg aatttttttc tcaacaaggt
     3301 aatcgcctga cttcggacaa gaccgtccta ccggcaaatc ccacgaggta aagtcacact
     3361 cagggtagcg gtcgcagcca tagaaaatac ggttacgctt tgttttgcgc tcaatgactt
     3421 ggccttgctg acaagctgga caagaaactc caatttcctt tgtgatggcc tttgtatgat
     3481 ggcactcagg aaagttacta caagcataaa acttgccaaa tctacccagc ttaacaacca
     3541 tcgggtggcc gcacagctca caatcaaaac cagccggctc gtccttgatt tgaatttttt
     3601 cgatctccgt ttcagccttg gttaactcct taacaaatgg cttgtagaat tggtcaatca
     3661 cattctgcca ggcttctttg ccgatctcta tctgatcaag cttatcttcc atatcagctg
     3721 taaatttgac atcaacaata tcagggaaga attccacaat caattgatta acaatttcgc
     3781 ctaattccgt cggctcaaag cgtttagcag ccagcttaac ataataacga cgctgaatca
     3841 catcgagtgt tggagcatag gttgatggcc ttccaacacc gttttcttcc agtgttttaa
     3901 tcaggcttgc ttctgaataa cgagctggcg gttgagtaaa gtgctgttca ggtgttaagg
     3961 taaccttttt aaccacttct ccttctgtca tttcaggaag catcttgctt ttatcagaat
     4021 cattgtaaac agccatataa ccgtcaaatt tcatctgact gccattggca acaaaaagga
     4081 cactattttg ctctaggtta accttaacag tatcaaacac agcagctgtc atctgactag
     4141 cgacaaagcg gttccaaatc aaggtataga gctttagctg atccttatct aaaaatttag
     4201 caatagcctc tggcgtatgg ttcacattag atggtcgaat agcctcatga gcgtcttgag
     4261 caccagtagc atttttaact cgattgccat gcttagagta ctgactaccg aaacgttcaa
     4321 caataaagcc tgcggcatca ttttgagcaa ctgggctgat acgagtagag tccgtacgca
     4381 tgtaagtaat taacccttgt gttccattag gaccaagact aatcccctca taaagctgct
     4441 gagcaaccat cattgtttta cgagtccgaa agttaatctt attggctgcg tcctgctgca
     4501 atgaggaggt tgtataaggt aaaggagcat gacgcctgcg ttcttttttc tcaaccttac
     4561 taaccataaa atcatcgcta cttaatcgag acaaaacaag cttaacatca tcattggtat
     4621 tgagcttcat ctttttgcca ttgaggccgt aaaagcttgc ttggaatttt tttgtccctt
     4681 ttttaaagag accatcaatt gaccaatatt cttcaggaac aaaggcctta atctcatgct
     4741 ctctgtcaat gattagcttt agagcaaccg attgcacgcg ccctgctgaa agcccctttt
     4801 taaccttttt ccagagaatt ggcgaaatgg aataaccaac aatacgatcc agtacacgac
     4861 gtgcctgctg tgagtcaacc aaatccatat caatttttct tgggccttca aaagcttctt
     4921 tgacggcatc ctttgtgatt tcattgaaaa cgacacgatt gttatcatca ggatcaagtc
     4981 ccaaaatatg tgataaatgc catgaaatgg cctctccctc acgatccggg tcacttgcta
     5041 gataaacctt tttagcattc tttgcttctt tttttaaggc attaatcagc ggacccttac
     5101 cacgaatatt aatatactgt ggctcataat gattgtcaaa atcaatagac attgatgatt
     5161 ttttcaaatc acgaatatga ccaaccgagg caacgacctt atactgacgt cccaaatatt
     5221 tttcgatggt tttagcctta gcaggtgatt caacaatgac tagatttttt ttagcagctg
     5281 ctgatttttt ctttgtagca gatcttttcg tctcttgttt tgacttagtt gctgtttttg
     5341 ttaccaattg acacacttcc tataacagtt atggttaaag cttctagcat aatatcccat
     5401 tttttaagaa ctgtcaacaa aaaattttct ataaatagga agaaaagtta agaatagtgg
     5461 tattctgaaa gaatgtctct gccatgagtg acacagctgg caccatcttt gatcagcttc
     5521 aaacagcccg ccgatgtccc attaagaata ttgtcaggta cgacaaaaat atcacgtccc
     5581 tcttccatag ctagctgaca ggtaatcaaa gagccagagc gctgcttagc ctcaacaaca
     5641 aggacacctc gactaagacc tgcgataata cggtttcttt cagggaaatg ataagacaag
     5701 gcggcctctc cagccccata ttcactgagc acgagatgac gctgagataa aaactcctgt
     5761 agctggtgat tttcctttgg atagtagcga tctaggccag tcccgataac agctatggtt
     5821 tgcccacctg ctttcaagca agcgagatga gcactggtat caatacctct agcaagcccg
     5881 ctgacaatga caaagtgatt cttaagctct ttgatgattt tgtaaacaga ccgcgtccca
     5941 atttcactgg attctctaga gccaacgact gccagcttag gcttttctaa caggcttaaa
     6001 tcaccttgat aaaagagtaa aacaggagga ttatagattt ccctcagggc caatgggtat
     6061 tgcttatcta ggatagataa gctcggaaac tggttgaatt ccttttttaa caaggcgaca
     6121 tttaattgct tgtaggtctc aataaataaa actggatttt tgcagcaaga aaccactgcc
     6181 atatctctaa gggatagaga cttgttatta cgctgctggt agtcaatcag gttaagaata
     6241 tttaaattag ttagcccagc cttttttaat ttataaagtt caaaattatt catcactgta
     6301 cctctctaat gatttattcg t
//
LOCUS       DARYYD010000088         5644 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.089, whole genome shotgun sequence.
ACCESSION   DARYYD010000088 DARYYD010000000
VERSION     DARYYD010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5644
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.089"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            198..953
                     /locus_tag="TV188_001851"
     CDS             198..953
                     /locus_tag="TV188_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002962809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEL1535174.1"
                     /translation="MSQKEVGHQFLARLGKKRLRPGGVEATNWLVQQGEFSSDCKVLE
                     VACNRCTTSIELAQTYQCHITAVDLDTKVLAEARKAIEAAQMQDYIHLTQANALKLPF
                     ADNSFDIVINEAMLTMLNDAAKEKALKEYWRVLKPGGRLLTHDVSYEADETKAIIEQL
                     RDTINVNVSPLQLDAWRQLLVKSGFTAVNYSYGNMTLMSPLGMIKDEGVVAAIRIMLR
                     GMKKENRKQFLKMRHFFNKTGRKLCYIAAVSQK"
     gene            981..1319
                     /locus_tag="TV188_001852"
     CDS             981..1319
                     /locus_tag="TV188_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEL1535175.1"
                     /translation="MSLIRKIPTSTVIDLKAEVPIEEDQILSRTLVQRKDLGITLFSL
                     DKGQEIGRHSSPGDAMVNVLSGVVDITIGEACYEVAAGETIIMPANIPHSLFAKEAFQ
                     MLLVVVKPEA"
     gene            1321..1626
                     /locus_tag="TV188_001853"
     CDS             1321..1626
                     /locus_tag="TV188_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1535176.1"
                     /translation="MLADLLELVRYHDDQIASRSLHQSLGFKQSVVLYAMYQGETISN
                     ESSPEGKLLLVLEGRLLVSLTDQAHDMKAGGLISISAHQFYHLEAATNCKYLQIEMV"
     gene            2377..3114
                     /locus_tag="TV188_001854"
     CDS             2377..3114
                     /locus_tag="TV188_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1535177.1"
                     /translation="MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLL
                     ANVTERGRHQLFFLDIQIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQ
                     VSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFATAKAQVQVPFSSLLF
                     IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRL
                     LYFKNGQSCMVSRLKMKALEASIKALH"
     gene            3487..3687
                     /locus_tag="TV188_001855"
     CDS             3487..3687
                     /locus_tag="TV188_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComC/BlpC family leader-containing
                     pheromone/bacteriocin"
                     /protein_id="HEL1535178.1"
                     /translation="MNTKTIEQFSTMTADMLAGVEGGWGYRWRCTDGYTSAWHLLRDT
                     AQENADNHMILYPGTVCRVYNA"
     gene            3754..4608
                     /locus_tag="TV188_001856"
     CDS             3754..4608
                     /locus_tag="TV188_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1535179.1"
                     /translation="MLLILDNISKSYGSKKVLSRISAQFTPGLYGLLGANGTGKTTLL
                     NIISQFTVPDSGEISLNHQQQPKNFYQNIGFLPQQFNYYQQFSGLEFLLYMAALKNVK
                     RKKALVEADRLLKLVGLYDVRKKKIASYSGGMKQRLGIAQALINDPLLLILDEPTVGL
                     DPKERVKFRNIISDLSEQKIIILSTHIVSDVEAVAKEVILLKHGQFIEKGSVDQLVQT
                     MIGKVWEIPVATESAPAFLTDYAVVNEKIVKNNRILRVVSDESPCYQANPVSPTLEDL
                     YIYHFRKE"
     gene            4614..>5644
                     /locus_tag="TV188_001857"
     CDS             4614..>5644
                     /locus_tag="TV188_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1535180.1"
                     /translation="MASLIPFEFKKLLRRQSVFGAIVVVLLAVGGLFYQHFFNGQISG
                     SSADQVHGRAAVAINQQIAEKHTGYLSDDLISRILNDYAKNQSDLKKKGVYSVVSHYA
                     ISHLVPKSTDKLIAINSTDKSLTFDNVHLKSREELGSALPLKELKLGNFAPWNQLFDV
                     TNSTYLLVVMLCLYITAPLFSGESSKKMNSILLTTVFGRGKLTLAKLAVSIAVSTLVF
                     AIASGLVFAVFATYFGFSGWDTSLQLNLYWIDPVINIMAFPEKMTLGIAFVYLLVFQY
                     IGLIFMTGIHALVSSLTKSPLTTFGISALIVYAPVFLMGIFPEGLMNKLLTFVSVQTF
                     GTQELLLKLA"
BASE COUNT         1718 a          923 c         1205 g         1798 t
ORIGIN      
        1 gtcaaaaggt cgtatagcac aagaaatatg agccaattct atgatttatc ataaaaacaa
       61 tcatcagaaa tgcttaagct tcattgagga tatgctttaa gtgtgatata gttgtagtaa
      121 tcatttattg atcaatttgt taacagttag tttattctaa gtgatgatat atagcagagc
      181 aaataggagg gcatgtgatg tctcaaaaag aagttggtca ccagttttta gctcgactgg
      241 gaaagaaacg actacggcct ggcggtgttg aggcgacgaa ttggctggtt cagcaaggag
      301 agttttcgag tgattgcaag gtcttggaag tggcctgcaa ccgttgcacg acctccattg
      361 agctggcgca gacttatcag tgtcatatta cagcagtaga tttggatacc aaggtactgg
      421 cggaggcaag aaaggctatt gaggcagcac aaatgcaaga ctatattcac cttacccaag
      481 ctaatgcctt gaagctgcct tttgcagata atagctttga tatcgttatt aacgaagcta
      541 tgctaaccat gttgaatgat gctgcaaagg aaaaagcact taaggaatat tggcgtgttt
      601 taaagccggg tggtcgccta ctaacgcatg atgtttccta tgaagctgat gaaacaaagg
      661 ctattataga gcaactaaga gatacgatta atgtgaacgt atcgccattg cagttagatg
      721 cctggagaca attgctggta aagagtggct tcacagcagt caattactcc tatggtaata
      781 tgacgctcat gtccccgctt ggcatgatta aagatgaagg ggttgtcgct gcgattcgta
      841 ttatgctgcg cggcatgaaa aaagaaaatc gaaagcagtt tttaaagatg cgtcatttct
      901 tcaacaaaac tggaagaaag ctgtgttata ttgccgctgt aagtcaaaaa taactagaat
      961 aatggtaaag gagaagtgac atgtcattga ttcgtaaaat tccaacaagc acagtcattg
     1021 atttaaaggc agaagtgcca attgaagagg atcaaatatt aagtcgaaca ctagttcaaa
     1081 gaaaagattt gggcataacc ctgttttcat tagataaagg acaagaaatc ggtcgtcatt
     1141 catcaccggg agatgcaatg gttaacgtgt taagtggagt agttgacatt actattggag
     1201 aagcctgtta tgaggtagct gctggcgaga cgatcatcat gcctgctaat attcctcata
     1261 gcttatttgc taaggaagcc ttccagatgc ttttagttgt tgtaaagccg gaggcttagc
     1321 atgttggctg atttattaga attagtaagg tatcatgatg accaaatagc tagtcgttcg
     1381 cttcatcaaa gcctaggctt taagcaatct gttgttttat atgccatgta tcagggagag
     1441 acgattagta acgaatcaag ccctgaaggt aagctcctgc ttgtcttaga aggaaggttg
     1501 ctggttagtc ttacggatca ggctcatgac atgaaagcag gcggattgat cagtatctct
     1561 gctcatcagt tttatcattt agaggctgca acaaattgta aatacctgca aattgaaatg
     1621 gtctaaaagt atagagtgac tctcttgaat cttgccccct aggctggtgt tttagctgcc
     1681 ttagggggct ttttgtgttt agtgtcataa ggtttagctg aagatctagc ttacttcaaa
     1741 tcactcaaag tgattaataa taataacaat tacctgtttt gatgataaaa agattgtttt
     1801 tatgataaaa taaatgacag aatatcccgg atacctaatg tatttgttac caataattct
     1861 agaaacttat tgcttggaga aggtatagct acaagcagct aatcatcaga tagcctcagt
     1921 aacctgacta gccattgtta gttttcctta tttaccattt aagacataat cagtaccatt
     1981 taagatttta actccctgct ccctagcttt gtgttagaat gtctgtgcaa ggagatcagt
     2041 gtgtggattg atagctgatg acttgtcaaa caaaagtgat agtcgttaag agctctctct
     2101 caaagaggta tgacttgcgg ctcgtgctag tatattatct gtggtaaaaa aattgtttga
     2161 ggcgcgtgat tcgctaaggc ctattgaaaa cgctgcaatg acaagttggt tagaagtcat
     2221 tgacaacctt tagttaataa gcttaacggt catggtttta atggtgatgc taaaaagata
     2281 ctgttcatga aggagagcgt tctagctatc acttgttcaa aaagctgctt tagtctccta
     2341 aaaaaacgat aagctaaagc aataaggagg ttctaaatga atatttttat tctcgaagat
     2401 gatctaggcc aacagtttag gcttgagatg aagattcaag agatattgga taagcatcac
     2461 tggacttgtg atcgttttga agtttatgga aagccctacc agcttctggc aaatgttaca
     2521 gagagaggca ggcatcagct tttctttctc gatattcaaa ttcgaaatga tgagaaaaag
     2581 ggcttagctg ttgctcgtga gatcagaaag cgtgaccctt atgccctcat tgtttttgtc
     2641 accacacatt ctgagcttat gccagtttct tttcgttatc aggtgtctgc tctagatttt
     2701 atcgataagg aattgtcaat gaaacatttc tcagatagga ttgaaagagc cattatatat
     2761 gcttatgaag agcaagaaaa tgtaacctca gagggcttat ttatttttgc aacggctaag
     2821 gctcaggtgc aggttccttt ttcaagccta ttgttcattg agacctctag tactcctcac
     2881 aagttgattt tgcattctca aaacgagcga atagaatttt atggctttct ttcagaggtt
     2941 cttaagcaag attccagact agtccaatgt catcgttctt atgttatcaa tccttacaat
     3001 gtttcgtttc ttgatcgtga taagcgttta ctctatttca agaatgggca gtcttgcatg
     3061 gtttcaagac taaaaatgaa agcacttgag gcgtctatta aggctttgca ttgacagtaa
     3121 aagaatgcca tgtggaagcc atcatttgtt ttttaatcaa cctcgttgat accatttacc
     3181 ttaagggata tttattataa atatatttag tcaaaactaa gaaaaagggg taacagttgg
     3241 tttctaatga tgctcagaga tatgatgtac atgcaaaaat caattatatc ataagaaaag
     3301 agagaaaaag atatagctcg tgaaaggtat ccatatgatc ttaactggta atttcagaag
     3361 aaaaattgac cattcacgac aaaataagaa ccattcaaga tttttgagtg tcgttgcttt
     3421 aaaaagcgct acactaagtt tgtcgagact gtagctagat aaaatcatta taaggaggta
     3481 ttcgatatga atacaaaaac aattgaacaa tttagtacaa tgactgctga tatgcttgca
     3541 ggcgttgaag gtggttgggg ttataggtgg agatgcactg atggttatac aagtgcatgg
     3601 catctattaa gagatacagc acaagaaaat gctgataacc acatgattct ttatcctggt
     3661 accgtttgtc gagtatataa tgcttaatgg ttaatcatct ggggagcagc gaagtggtgc
     3721 tgttccctgg gtttttactt aggaggaatg acaatgttgt taatactaga taatatttct
     3781 aaatcttatg gaagtaaaaa ggtgttgagt cgtatttctg cacaatttac accaggcttg
     3841 tatgggttat tgggagcaaa tgggaccggt aaaacgactt tattaaacat cattagtcag
     3901 tttacagttc ctgatagtgg agaaattagt ttaaatcatc aacaacaacc aaaaaacttt
     3961 taccagaata ttggcttttt acctcaacag tttaattatt atcagcagtt ttccggttta
     4021 gaattccttc tttatatggc tgctttgaag aatgttaaac gtaaaaaggc tttagtagaa
     4081 gctgatcggt tattaaagct ggtaggtctt tatgatgtta gaaaaaagaa aattgcttct
     4141 tattctggcg gtatgaagca gcgattgggt attgctcagg cacttatcaa cgatccttta
     4201 ctgttaattt tagatgaacc aacagtcgga cttgatccaa aggaacgtgt aaaatttaga
     4261 aatattatca gtgatttatc agagcaaaaa attattatcc tatcaacaca tattgtatct
     4321 gatgtagaag cggttgcaaa ggaggtaatc cttctaaagc atggtcagtt tatagaaaaa
     4381 ggaagtgttg atcagttagt tcaaacaatg atcggcaagg tatgggagat tcctgttgct
     4441 acagagagtg caccagcatt tttgactgac tatgccgttg tcaatgaaaa aattgtaaaa
     4501 aataatcgta tcttacgtgt tgtgagcgat gagagtcctt gttatcaggc aaatcctgtg
     4561 tcaccaacat tagaggatct ctacatttat cattttagaa aggagtgaat tctatggcat
     4621 ctctcatacc ctttgagttt aaaaaattat taagacgaca gtcggtattt ggtgcgattg
     4681 tagtggtctt attggctgta ggtggtcttt tttaccagca tttttttaac ggtcagatca
     4741 gtggctcttc tgcagatcag gttcatggac gtgcagctgt agcaattaac caacaaattg
     4801 ctgagaagca tacaggttat ttatctgacg atctgattag tcgtatcctc aatgattatg
     4861 ctaaaaatca atcagaccta aaaaagaagg gtgtatatag tgtggtatca cattatgcta
     4921 tctctcattt agtgcctaag tctactgata agcttatcgc tattaatagc actgataagt
     4981 ctctgacatt tgacaatgtt catctcaaat cacgtgaaga gttggggtcc gctctgcctt
     5041 tgaaagagtt gaagttaggt aattttgctc cttggaatca gttgtttgat gtaaccaata
     5101 gtacttatct tcttgttgtt atgctttgtc tttatataac ggctccttta ttttcagggg
     5161 aatcatctaa aaagatgaac tctatcttat tgacgactgt ttttggacgt ggtaaattga
     5221 ctcttgctaa attagcagtt agcatagctg tcagtacttt ggtatttgca attgctagtg
     5281 gtctggtctt tgctgtcttt gcgacctatt ttggttttag cggctgggac actagcttac
     5341 aactcaattt gtattggatt gatccagtga taaacattat ggctttcccg gaaaagatga
     5401 ccttaggcat tgcgtttgtc tatttattgg tgtttcagta tattggcctg atatttatga
     5461 caggcattca tgcactagtt tcatctctaa ctaagtctcc tctaaccact tttggtatat
     5521 ctgctcttat tgtatatgca ccggtctttc taatgggaat ttttccagaa ggtttgatga
     5581 acaaactgtt aacatttgta tccgtacaaa cctttggtac acaagaatta ttattaaaat
     5641 tggc
//
LOCUS       DARYYD010000089         5578 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.090, whole genome shotgun sequence.
ACCESSION   DARYYD010000089 DARYYD010000000
VERSION     DARYYD010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5578)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5578)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5578
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.090"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..935
                     /locus_tag="TV188_001858"
     CDS             <1..935
                     /locus_tag="TV188_001858"
                     /inference="COORDINATES: protein motif:HMM:NF019104.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535181.1"
                     /translation="FSLNEPIAARVTKPTYNRQQLLKNLENSRLATESSRFKSYVARE
                     KLINTLRKQNADLNLITFREKAIEIFNRDLKGNSWVSIRQADEFVETLDDYAQLSVDN
                     GAVSTKADFYKMYSNKNYIYLDGFIKNIKQLYIKTGASSIVNGQDLYNAIEQYGTIGR
                     GKSGNFATSMAEDIALLYDSSGNLVSSGMIEAIKGVDEGKYLSGAFQYEYSPQFVKSF
                     DQIGEVRTVTGKTPGSSLLNIPGAKTWAGKNMALSQSELMMPSIDTSNLKLEDVLLSM
                     ESTGIYTLNNPTIVLKDGTKKIVEGQFIIRKLGN"
     gene            937..1443
                     /locus_tag="TV188_001859"
     CDS             937..1443
                     /locus_tag="TV188_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535182.1"
                     /translation="MTQTFFNNDVDERRRQLYLDARSKGHLEKCFRGDSGFKINAKDS
                     YFQSITDINVLIERCLYPLYDLGDSIIPHETERILSQFSTSKNVVELYQVVSYIFYQK
                     NNKLLKKNFSFYIDFNPMIPDLVFSVKRLSPENIVTDDEKAMVGFIKNMFQKIPQVQS
                     YLEAQNCK"
     gene            1587..2009
                     /locus_tag="TV188_001860"
                     /pseudo
     CDS             1587..2009
                     /locus_tag="TV188_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678587.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2538..3263
                     /locus_tag="TV188_001861"
     CDS             2538..3263
                     /locus_tag="TV188_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEL1535183.1"
                     /translation="MLEKPSKAELLTALKDGLIVSCQALPGEPLYSEAGGIMPLMAKA
                     AEEAGAVGIRANGVRDIKEIQAVTDLPIIGIIKKEYPPQAPFITPTMAEVDALAALDV
                     AVIALDCTQRERHDGLAIADFIRSIRKKYPEQLFMADISTLEEGLVAYEAGIDFVGTT
                     LSGYTPYSRQGTGPDMELISALCDAGVSVIAEGKIHSPEEARAVQALGVAGIVVGGAI
                     TRPKEIAERFVAALKKEEKSHGF"
     gene            3253..4764
                     /locus_tag="TV188_001862"
     CDS             3253..4764
                     /locus_tag="TV188_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEL1535184.1"
                     /translation="MDFKKFSKLGQAFMLPISILPVAGLLLGIGGALSNSNAIAQFPI
                     LNQAWLQAIFTIMSTAGNAVFANIALIFAIGVAVGLANGDKGTAGLSGAVAYLVFTAT
                     ISGYLTLFSAKDAQIDTGVLGALTVGLVVVSLHNKYRKIELPAFLGFFGGSRFIPIVS
                     SLAAIVIGSVFYVIWPPIQNLLVVFGEKIADMGSIGTFLYGFFLRLTGAVGLHHTIYP
                     MFWYTSLGGSEVVAGETIQGAQNIFFAQLADANHTDLFTYGTRFFAGRFATMMFGLPA
                     ACLAMYHAIPKANRKKVGSFYSSSALTSLLTGITEPIEFAFLFVAPWLYVVHAFLDGC
                     SFLVADLLKIRIGNSFSGGLIDFLIFGVFQGNDHTNWLLVIPVGIVWFMVYYFVFKFF
                     VSKFQVAVPGMVAQVEAEGQAETTNTQSSSLREVSLAIIEALGGQANIEDVTACATRL
                     RVSLSDSSLVNKNVLTSLGATAVLDVKNGIQAIYGGKAILYSQEINQLLGRED"
     gene            4766..5281
                     /locus_tag="TV188_001863"
     CDS             4766..5281
                     /locus_tag="TV188_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEL1535185.1"
                     /translation="MIKKWKQLLSAKKADALSDRILSVAKGQLVPITSVSDPVFSERL
                     MGDGFAIIPQEGAIYAPVTGRVMTVFPTKHAYGIVTPAGLEVLIHIGVDTVELGEAAF
                     SSDIVAGQEVVAGQLLAQVSLPVLEAAQKDSTVMVVFTNSQDIADMRLADAGAVAARA
                     EVGQVRLKATL"
BASE COUNT         1648 a          924 c         1305 g         1701 t
ORIGIN      
        1 ggtttagctt gaatgagcca atagcagcta gggtgacgaa accgacctac aaccgccagc
       61 agcttttgaa gaaccttgaa aacagcaggc tggcaacaga gagctcaagg tttaagagct
      121 atgtagcaag agaaaagtta attaatactt taagaaaaca gaatgctgat ctaaatctta
      181 tcacatttag ggagaaagcc atagaaattt ttaataggga tcttaaagga aatagttggg
      241 tttcgataag acaggctgat gaatttgtag aaacattaga tgattatgct caattatcag
      301 tagataacgg tgctgtttct acaaaagcag atttttataa gatgtattca aataagaact
      361 atatatattt agatggcttt ataaagaata taaaacagct ttatattaag acaggtgcat
      421 catcaattgt gaatggtcaa gatttgtata atgcaattga gcaatatggt accattggaa
      481 gaggtaaatc gggaaatttt gcaacaagta tggctgaaga tatagcatta ctttatgata
      541 gtagtggtaa tttagtttct tccggtatga tagaggctat caaaggggta gatgaaggta
      601 agtatttgtc tggtgcattt cagtatgaat atagtcctca gtttgttaaa tcttttgatc
      661 aaatcggtga agtgagaaca gttactggta aaactccagg ttcttcactt ttaaatattc
      721 caggggctaa aacttgggca ggtaaaaata tggctttgtc acagtctgaa ttaatgatgc
      781 catctattga tactagtaac ttaaaattgg aggatgtatt attaagtatg gaatcaacag
      841 gaatttatac cttgaataat cctacaatcg ttttgaaaga tggcactaaa aagattgttg
      901 aaggacaatt tataattaga aaattaggta attaatatga cacaaacatt ttttaacaat
      961 gacgttgatg aaagacgtcg acaactttac ttagatgctc gttcaaaggg acacttagag
     1021 aagtgcttta gaggggattc tgggtttaaa ataaatgcta aagactcata ttttcaatcg
     1081 atcacagata taaatgtgct tattgagcgc tgcttgtatc ccttgtatga tttaggagat
     1141 agcattatcc cacatgaaac tgaaagaata ctgtctcaat tctcaacttc aaaaaatgtt
     1201 gtagaattat atcaagttgt gtcatatatt ttctatcaaa agaacaacaa actactaaag
     1261 aagaactttt ccttttatat tgattttaat cctatgatcc ctgatttagt tttttctgtt
     1321 aaaaggttat ctcctgaaaa tatcgtgact gatgatgaaa aagcgatggt tggttttata
     1381 aaaaacatgt ttcaaaaaat tcctcaggta cagtcttatc ttgaagctca aaattgcaaa
     1441 tagtttagat gaatacttga aaaatggatt tgaaatagct taaataaaaa tagagtatgc
     1501 ttttcaatca gacgaggtaa gggtattatt ggaaaaagat tgagcagtat ttatcgatta
     1561 agctataaaa acgaaagata acacacatgg cacgcagtca attaacatgg gaagatgtta
     1621 gtcaatatga ggaaatcaag ggttatggcc aacaggtttg gaagcatcag ggagaatatt
     1681 atctagtcag agaagaagga ggaattgctg tacaacgagt agtgtataaa ctccctaatg
     1741 agcttttcca attactggaa agtgaccgaa aatttttatt agaaatagat ttttatgtca
     1801 aaaataactg ctggctgcca acagaagagg agaaaatagc tagtgataaa gcatttctac
     1861 aaagatcccc aatagcatta attgcagatc caaccagttg ggaactgttt acctaagaag
     1921 agctaagaaa actaattcca attgcggagc aaaaatggat agattggaag ggaaaactgc
     1981 cagatgatta tgtcagtcct ttgaaataat gtttaagata gcggatctga gggcagctat
     2041 gttaggggcc gttgttagct gtattaggta ggtgaaaagt ggttattttt gggtacaatc
     2101 aaaagttcta tatataaccc ttgcggtgga gttacccact acgggtattg tagagcttga
     2161 aaagctgggt gcgagagagg actggactgg ttctctcttt tttgtctctt tgtcaagctt
     2221 atcaagcaat aataggacct aaggtagttc ttgttgagac atattgccgt atttggcctt
     2281 agctggctgg caaaaaggct tttatggtaa gaaggtatgt cttgtaaggt tttgctgttg
     2341 ttgtatcaat tagtaaatag ctcaataggc tagctctttg ccatacttaa ggctattgaa
     2401 tatactttca gaaaacaagg atttttctct gaaaatgaaa gtacttccta aaagtgggct
     2461 gtctattgaa agtgttttaa tatctgctac aataaagatg tgaacgttct ctaaaattaa
     2521 taaaaggagt agaaagcatg cttgaaaaac caagcaaggc agagctactg acagctctga
     2581 aagacgggct gatcgtttcc tgtcaagctc tgccgggcga gcctctctat tcagaggcag
     2641 gaggtatcat gcctctgatg gcaaaggcag cagaggaagc aggagcagta gggataagag
     2701 ctaatggggt tcgagatatt aaggaaatcc aagcggtgac ggatctgcca atcataggga
     2761 tcatcaaaaa ggagtatcct ccgcaagcgc cctttatcac gccaaccatg gcagaggtag
     2821 acgccttagc ggccttagat gtagcggtga tagccttgga ttgtacgcaa agggagcgtc
     2881 atgatggctt agcgatagcg gactttattc gatcgataag gaagaagtac ccagagcagc
     2941 tgtttatggc agacatcagt acgcttgaag agggtctagt agcctatgag gctggtatag
     3001 attttgtagg gacgacctta tcagggtata cgccttatag tcgtcagggg acaggtccgg
     3061 atatggagct gataagtgcc ttgtgtgatg caggggtatc agtgatagct gagggcaaga
     3121 ttcatagtcc agaggaggcc agggctgttc aggctttggg agtagctggt attgtggttg
     3181 gtggtgctat taccagacca aaggaaattg cagagcgctt tgtggcggct ctcaagaagg
     3241 aggagaaatc acatggattt taagaaattt tcaaaattgg gtcaagcctt tatgctgccg
     3301 atctcaatct taccagttgc tggtttgttg ttggggattg gtggggccct gtcaaatagc
     3361 aatgccattg cacaatttcc gatattaaat caagcatggc tacaggctat ttttaccatt
     3421 atgagcacag caggtaacgc tgtttttgct aatattgcct tgatttttgc gattggtgtt
     3481 gctgttggct tagccaacgg agataaagga acagccggtc tttcaggtgc tgtggcttat
     3541 ttggtcttta cggcaaccat tagcggctat ctgactcttt tttcagcaaa ggacgctcag
     3601 attgatacgg gtgttttagg ggctttgacg gttggcttag ttgttgttag ccttcacaat
     3661 aagtaccgaa agatcgaact gccagccttt ttaggcttct ttggcggctc tcgttttatt
     3721 ccgattgttt cctcattggc agcgattgtg attggtagtg ttttctatgt catttggcca
     3781 cctattcaaa atctcctagt agtgtttggt gaaaaaattg cggatatggg gagcatcgga
     3841 acattcttgt acggtttctt tttacgtctg acaggagcag tagggctgca ccacaccatt
     3901 tacccaatgt tttggtatac atcacttggc ggtagtgagg ttgtagcagg tgagactatc
     3961 caaggagcac aaaatatctt ctttgcgcaa ttggctgatg ctaaccatac cgacttgttt
     4021 acttacggga cacgcttttt tgcaggacgt tttgcaacca tgatgtttgg actacctgct
     4081 gcctgtcttg ctatgtatca cgctattcca aaggctaatc gtaaaaaggt tggtagcttt
     4141 tattcaagta gtgccttgac ttccttacta acagggatca cagagcctat tgaatttgcc
     4201 tttttatttg tagccccttg gctctatgta gttcatgctt tcttagatgg ttgttctttc
     4261 ttagttgctg atttattaaa gattcgtatc ggtaattcct tctcaggtgg tttgattgac
     4321 tttttaatct ttggtgtgtt ccaaggaaat gatcatacca actggctact tgttatccct
     4381 gttggtatcg tgtggtttat ggtttattac tttgtcttta aattctttgt gagcaaattc
     4441 caggttgctg taccgggaat ggtagctcag gtagaagcag aaggacaagc agagactact
     4501 aatactcaaa gctcatcact tcgtgaggtg tcattagcta ttattgaggc tttgggagga
     4561 caagctaaca tcgaagatgt aaccgcttgc gcgactcgct tgagagtgtc tctgtcagat
     4621 agcagcttgg ttaacaagaa tgttttaacc tcactgggag caacagctgt attagatgtt
     4681 aaaaatggca ttcaggctat ttatggtggt aaggctatct tgtatagtca agaaatcaat
     4741 caactattag gtagagaaga ttaacatgat aaagaagtgg aagcaattat tatcagcaaa
     4801 aaaagctgat gcgttaagcg atcgtatttt atcagtggct aagggacaat tagttcctat
     4861 taccagtgtc agtgatcctg tcttttcaga aaggctaatg ggcgatggct ttgctattat
     4921 tcctcaggag ggcgctattt atgcacccgt aacaggaagg gtcatgacgg tttttccgac
     4981 caagcatgct tatggcatcg ttactccagc tggtcttgag gtcttgattc atatcggtgt
     5041 tgatactgtt gagctgggag aagctgcctt tagctctgat attgttgctg gtcaggaggt
     5101 agtagctggg cagttattgg ctcaggtctc tttgccagtg cttgaagctg ctcaaaaaga
     5161 cagcaccgtt atggttgtct ttacaaactc acaggacatt gctgatatgc gtcttgctga
     5221 tgctggagca gttgctgcta gggcagaagt cggccaagtt aggctaaagg ctactctcta
     5281 gctagaggct atcgatccag tccttgatga caactaaaag gtcatatgaa aaaactgcac
     5341 cccagcactt ggctaagtcg gtcaatgcct tggggtgctt ttattattgt cagcaatcag
     5401 caggctttga ttgtcctatc ttttaacctc tatttaaatg ttaacagctg tcgtatgtgc
     5461 cttgtggcaa ataaaagaaa agctcagcga cctgtttctc atattgctta gcacatttta
     5521 ttttaggggg gctattatat cctccccagt atacaagggc tgaaaaagga aaatagag
//
LOCUS       DARYYD010000090         5533 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.091, whole genome shotgun sequence.
ACCESSION   DARYYD010000090 DARYYD010000000
VERSION     DARYYD010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5533
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.091"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            32..874
                     /locus_tag="TV188_001864"
     CDS             32..874
                     /locus_tag="TV188_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HEL1535186.1"
                     /translation="MNKAKLTALCHKVSKEVGLSFNAVMLYYFLESILKKLAGSKYSE
                     RFIFKGGFLLSSVVGIDSRSTVDIDFLLRNMQLSEENIVQMLNETLKPEEFDDIFYEL
                     QNIVPIKEEDQYGGFRANILCKMENIRQIVPLDIATGDVITPHPIDYKYVSSFGEEEI
                     IIKAYPIETMLAEKIQTIYARGFLNSRSKDYYDLYIIYKLKDKDVNVEILREACRKTF
                     SYRKTEFDIGKIIDLLEKLKINEAFLKRWQAYSRKNLYAKDITFEEVLDNGIKMVEKI
                     KNEN"
     gene            1046..2758
                     /locus_tag="TV188_001865"
     CDS             1046..2758
                     /locus_tag="TV188_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HEL1535187.1"
                     /translation="MQTLVISEKPSVAISISKVLGATKKKDGYNEGNGYRVSWCVGHL
                     IQMANPDAYDEKYAKWDMADLPIIPKDYKYEVAKATKKQFNILKKLMNDKEIDTVINA
                     CDAGREGESIFRLVYNQVNCKKKMKRLWISSMEDSAIKEGFDHLKDGKKYDNLFESAQ
                     ARAIADWLVGMNISRLYSCLYNQNYSVGRVQTPTLAMIVKRDDEIANFKKEKYYTVEL
                     SMDGFILSTDRIDDKVAAEQLINLVGDKIEITDVIQNEKITKPDLPFDLTTLQRECNK
                     YFGYSAKQTLDYAQSLYEKKLITYPRTDSRCLTEDMITSMINNILGQNDFDTGRIKVI
                     FNSSKVTDHHAIIPTVSSMSEDLLSIPESEAKVYGLIFNKLHASVGYPLIENTTKIVV
                     TFDGFKFTSSGKVIKDEGFTKYLKEYKTKKNEDIELPNVNIGDSLKIKDKEIKEKYTQ
                     PPKHFTENTLLKSMETAGNDALKKGIEVERKGIGTPATRAGIIENLIYKGFIQRDKKN
                     LVATHKGISLITIVADNFKSAETTAKWEMELSDISQGKSSKEEFLRRVEAEIRNELSR
                     YKKD"
     gene            2762..3313
                     /locus_tag="TV188_001866"
     CDS             2762..3313
                     /locus_tag="TV188_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HEL1535188.1"
                     /translation="MFDTLIKFSKDREKLDFYATDKRAIHELLKREQFLSPIYEPACG
                     MGHIGKVLEEYGYKVKATDICYRGYGEEREVDFFTVTENILDIVTNPPYFCASEFLRH
                     ALEISGPKVKIAMLFRLAFLEGQSRYELFRKYPPKRVYVFSKRLNCAKNGEFEKYKSS
                     AIAFAWFIWEVGYKGITELRWIR"
     gene            3355..4101
                     /locus_tag="TV188_001867"
     CDS             3355..4101
                     /locus_tag="TV188_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1535189.1"
                     /translation="MDKNEVLQSQENQTKEVMQEIKEEYTKTADFLEEHINQQLVIAK
                     EMKEEMQNKDFDVNIKELKALKEEITGLKAEIKRLNEMENITFGSLIIRDIKSVGNTL
                     INLQEKAVGSIKHLYDNMKHQLSYNLTKAQEKFVQMKIGIVKGLVNSMQDFIKDQQKK
                     LDSCLAKLDNLSKEIQKDEEKLEKGNLNKEKTLIKKREQSIEEKESQKEKMEKKPSVL
                     KKLKENQQKIKQEEKNKDIKALKKDKGMEL"
     gene            4118..>5533
                     /locus_tag="TV188_001868"
     CDS             4118..>5533
                     /locus_tag="TV188_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEL1535190.1"
                     /translation="MNDLIKNYENIPDEMKKEKRWCLYKIIQRDGKNTKLPLMPNKEP
                     AKSNDKATWNSYEDCIMALKHNVGEGLGFFLGDGYIGIDIDKVSDDIMEYNTNHHVSS
                     MTADFLREVSTYAEISPSKTGLHFIGKGEVPGERKRYKNLEIYDKDRFFTVTGNVIKD
                     RDRSKIESIDSELKPLYEKYMPKTNKISAENKRSPTVTSYNGDQDILEKLFDRGYFSY
                     AGEDLRQIYYGNYERYFNSQSEADFFMLQRLLYYTGNVEMAISFMESSGLKREKWYKR
                     RGNTDYIHYIADKAISSINQFYDWEKVYTSKEKIEEKRYENKKKKEGDTVPRYEFDEV
                     KQILDFAKEEFKENIDRYETYLKVMGNNYKYPYFNQLSIYTVNENATACAEYDYWKSI
                     GRNVNRGEKGIPVLDIEREKIKYIFDASQTVSLNHNISEVKLWEYSNNKHVAALDTLI
                     DVFKEKNSNLIFSTEDKINTIV"
BASE COUNT         2252 a          653 c         1132 g         1496 t
ORIGIN      
        1 aataaagtaa gagaggttat ggaggtggct tatgaataaa gctaaattaa cggctctttg
       61 ccataaagtt agtaaagaag tcggtctttc gtttaatgct gttatgttat attatttttt
      121 agaaagtatt ttaaaaaaat tagcaggaag caaatatagt gaacgattta tttttaaggg
      181 cggctttttg ttatcaagtg tagttggaat tgattcaaga agtactgtag atatagactt
      241 tcttttgaga aatatgcaac tatcagaaga aaatattgtt caaatgctga acgaaacttt
      301 aaaaccggaa gaattcgacg atatttttta tgaattgcaa aacattgtgc caatcaaaga
      361 agaagatcaa tatggaggat ttcgtgcaaa tatcttatgt aaaatggaaa atataagaca
      421 gattgtacca cttgacattg caacaggaga tgttattaca cctcatccga tagattataa
      481 gtatgtgagt tcttttggag aagaagaaat aataatcaag gcttatccga tagaaactat
      541 gcttgcagaa aaaatacaaa ctatttatgc aagaggattt ttaaatagta gaagtaagga
      601 ttattacgat ctttatatta tttataaatt aaaggataaa gatgtaaatg tagagatatt
      661 aagagaggct tgcagaaaaa cttttagtta tagaaaaaca gaatttgaca taggtaaaat
      721 catagactta ctggaaaaat tgaaaataaa tgaagccttt ttgaaaagat ggcaagctta
      781 ttcaagaaaa aatctgtatg cgaaagatat aacttttgaa gaagtattgg acaacggaat
      841 aaaaatggtg gaaaaaataa agaatgaaaa ttagcatata acggttttac aatgaaaaga
      901 aggcgtcaaa catttttttg taagttagtt cccaaacagg aaaatggatt aaaaaataga
      961 aaatgaaata tataaaactt taaaagacaa ttggagaaat gcaaactctg attgtctttt
     1021 ttcatgtaga aaaaaggagg aatttatgca aacactggtg ataagtgaaa aaccgagtgt
     1081 tgcaataagc atatcaaagg tgcttggagc aacaaaaaag aaagacggat ataatgaggg
     1141 aaatggatat agggtaagtt ggtgtgttgg tcatttaatt cagatggcaa atccggatgc
     1201 ttatgatgaa aagtatgcca agtgggatat ggctgattta ccgattattc ccaaggacta
     1261 taagtatgaa gtagcaaagg caaccaagaa gcaattcaac atccttaaaa agctgatgaa
     1321 tgataaagaa attgatacgg ttataaatgc ttgcgatgca ggtcgtgagg gagagagcat
     1381 ttttagactt gtttataatc aagtgaattg taaaaagaaa atgaaacgcc tttggatttc
     1441 atctatggaa gatagtgcga ttaaagaggg ttttgatcat ctaaaagacg gaaagaaata
     1501 tgacaatctc tttgaatcgg cacaggcaag agccattgca gattggttag tcggaatgaa
     1561 tattagtaga ctttattcct gcttatataa tcaaaattac tctgtcggta gggtgcagac
     1621 gccaactctt gccatgattg taaaacgaga tgacgagata gcaaacttta aaaaagaaaa
     1681 atattatact gtagagctat ctatggacgg ttttatactt tccacagaca gaattgatga
     1741 taaggtagca gcagagcagc taatcaattt agttggtgat aagattgaaa ttaccgatgt
     1801 cattcaaaat gaaaagatta caaagccgga tttacctttt gacctgacaa cacttcaaag
     1861 agagtgcaat aaatattttg gatactcagc taagcagact cttgattatg ctcaaagtct
     1921 gtatgagaag aaacttatta cctatccaag aacagacagt agatgcctta ctgaagatat
     1981 gattacaagt atgataaata acatattggg acaaaatgac tttgatacag ggcgtattaa
     2041 ggtcattttt aattcaagca aggtaacgga tcatcatgct attataccga cagtaagttc
     2101 aatgagtgaa gatttattga gtattccgga gagtgaagca aaagtgtatg gacttatttt
     2161 taataagtta cacgcaagtg tgggctatcc tttaatcgag aatacaacaa agattgtagt
     2221 gacttttgac ggctttaaat ttacaagttc cggaaaagta attaaggatg aggggtttac
     2281 taagtattta aaggaatata agacgaaaaa gaatgaagat atagaacttc caaatgtaaa
     2341 tataggtgat agtcttaaaa tcaaggataa agaaatcaaa gaaaaatata cgcaacctcc
     2401 aaaacatttt acggaaaaca ccttattaaa aagcatggaa acagcaggaa atgacgcttt
     2461 aaaaaaaggt attgaggttg aaagaaaggg tattggcaca cccgcaactc gtgcagggat
     2521 tatagaaaat ctaatttaca aaggctttat tcaaagagat aagaaaaatc ttgtagctac
     2581 acataaagga attagtctta taacaattgt tgcagacaac tttaaatctg ctgaaacaac
     2641 tgcaaagtgg gaaatggagt tgtctgatat ttctcaaggg aaatcttcaa aggaagaatt
     2701 tttaagaaga gtagaagctg agataagaaa tgaattatcc cgttataaaa aggattagtc
     2761 tatgtttgat actctaataa aatttagtaa agacagagaa aaattggatt tttatgccac
     2821 agataaaagg gcaattcatg aacttttaaa aagagagcag tttctatctc ctatttatga
     2881 gccggcttgt ggaatggggc atatcggaaa agttctggaa gaatacggtt ataaggtaaa
     2941 agctacagat atttgttata ggggatatgg agaagaaaga gaagttgatt tttttacagt
     3001 aacagaaaat atattggata tagtaaccaa tccaccatat ttttgtgcaa gtgagttttt
     3061 aaggcacgct cttgaaatat caggacctaa agtaaagata gcaatgctat ttcggttggc
     3121 ttttttggaa ggtcaatcaa gatatgaatt atttaggaaa tatcctccaa agagagtata
     3181 tgtattttcc aaaaggctta attgtgcaaa aaacggagaa tttgagaaat acaaaagcag
     3241 tgctattgcc tttgcctggt ttatatggga ggtgggatac aaaggtatta cggagttaag
     3301 gtggattaga taaaaggatg gaataaaaca actgaaaaaa cgaaggagga tagtatggat
     3361 aagaatgaag tattacaatc acaggaaaat cagacaaagg aagttatgca ggagattaaa
     3421 gaggaatata ccaaaacagc tgacttttta gaagaacata taaatcagca gcttgtgatt
     3481 gctaaggaaa tgaaagaaga gatgcaaaat aaggactttg atgtaaatat caaagaattg
     3541 aaagcactca aagaagaaat caccggatta aaagctgaaa ttaaacgatt aaacgaaatg
     3601 gaaaatataa cttttggttc attgattata agagatatca aatctgtagg aaataccctt
     3661 atcaatttac aggaaaaagc ggtaggaagt attaaacatc tgtatgataa tatgaaacat
     3721 cagctttcct ataaccttac caaagcacag gaaaaatttg tacagatgaa aataggaatt
     3781 gtaaaaggat tggtaaattc catgcaggat tttatcaagg atcaacaaaa gaaactggat
     3841 agttgcttag caaaacttga taatctatct aaagaaattc aaaaagatga agaaaaactg
     3901 gaaaaaggca atctgaataa agagaaaacc ctgataaaaa aaagggaaca aagcatagag
     3961 gaaaaagaaa gtcaaaagga aaagatggag aaaaaaccgt ctgtgctaaa aaaattaaag
     4021 gaaaatcagc aaaaaatcaa gcaggaagaa aagaataaag atataaaggc acttaaaaaa
     4081 gataagggaa tggaactata aaaaagaggt ggtagttatg aatgacctca taaaaaacta
     4141 tgaaaatatt cctgatgaga tgaaaaaaga gaagcgttgg tgcctatata aaatcattca
     4201 aagagacggg aagaacacga aacttccact aatgccaaat aaagagccgg caaaatcaaa
     4261 tgataaagct acatggaata gctatgagga ttgtatcatg gcattaaaac ataatgttgg
     4321 cgaagggctt ggctttttct taggagatgg atacattgga atagatattg ataaagtaag
     4381 tgatgacatt atggagtaca atacgaatca tcatgtaagc tctatgacgg ctgatttttt
     4441 aagagaagtt tccacctatg ctgagatttc tccatcgaaa acaggactac attttattgg
     4501 aaaaggagag gtgccgggag aaagaaaaag atataaaaat cttgaaattt atgataagga
     4561 taggtttttt acagttaccg gtaatgttat aaaggataga gataggagca aaatagaaag
     4621 tattgacagt gagctaaagc ccttatatga aaaatatatg ccaaagacaa ataaaattag
     4681 tgctgaaaat aaaagaagtc caacggttac ttcttacaat ggggatcagg acatattaga
     4741 aaagttattt gacaggggat atttttcata tgcaggagaa gatttaagac aaatttacta
     4801 tggtaattat gaacgctatt ttaacagcca atcggaggct gattttttta tgctacaaag
     4861 gctgctttac tatacaggaa atgtagaaat ggcaatatca tttatggaaa gtagcggact
     4921 gaaaagagaa aaatggtata aaagacgagg caataccgat tatatccact atattgcaga
     4981 taaggcgata agctctatca atcaatttta tgattgggaa aaagtatata catcaaagga
     5041 aaaaatagaa gaaaaaagat atgaaaataa gaagaaaaag gagggagata cagtgccaag
     5101 atatgaattt gatgaagtca aacagattct tgattttgca aaagaagaat ttaaagaaaa
     5161 tatagacagg tatgaaactt atctcaaagt gatgggaaat aactataaat atccgtactt
     5221 taaccagctt agcatatata cggtaaatga aaatgcaact gcttgtgcag aatatgacta
     5281 ttggaaaagt ataggaagaa atgtaaatag aggagaaaaa ggaatacctg ttttagacat
     5341 tgaaagagag aagataaagt atatctttga tgcaagtcag acagtaagtt taaatcacaa
     5401 catttctgaa gtaaagttat gggaatatag caataataag catgtagctg ccttagatac
     5461 tcttatcgat gttttcaaag aaaaaaacag taaccttata ttttctactg aagataagat
     5521 aaatacaatc gtt
//
LOCUS       DARYYD010000091         5468 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.092, whole genome shotgun sequence.
ACCESSION   DARYYD010000091 DARYYD010000000
VERSION     DARYYD010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5468
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.092"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            227..1780
                     /locus_tag="TV188_001869"
     rRNA            227..1780
                     /locus_tag="TV188_001869"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2002..2074
                     /locus_tag="TV188_001870"
     tRNA            2002..2074
                     /locus_tag="TV188_001870"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2035..2037,aa:Ala,seq:tgc)
     gene            2382..5281
                     /locus_tag="TV188_001871"
     rRNA            2382..5281
                     /locus_tag="TV188_001871"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            5366..>5468
                     /gene="rrf"
                     /locus_tag="TV188_001872"
     rRNA            5366..>5468
                     /gene="rrf"
                     /locus_tag="TV188_001872"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1577 a         1102 c         1576 g         1213 t
ORIGIN      
        1 tcgtatacta gtgaagctgt cggcgagcac tagctcaagt taatgaaaaa aaggtaaaaa
       61 aagtagttga caaaggcagt ctaagctgat agaatgtaat agttgtctcg tgagacaaag
      121 acctttgaga actgaataag acgacctaaa cgtgcgggtt acggaagtaa cctgtcaata
      181 aagaaacaag tcagtaatga cgtcgagtta agagctcaaa cactgaatta acgagagttt
      241 gatcctggct caggacgaac gctggcggcg tgcctaatac atgcaagtgg aacgcacaga
      301 tgatacgtag cttgctacaa ttatctgtga gtcgcgaacg ggtgagtaac gcgtaggtaa
      361 cctagcttat agcgggggat aactattgga aacgatagct aataccgcat aaaagtggtt
      421 gacccatgtt aaccatttaa aaggagcaac agctccacta tgagatggac ctgcgttgta
      481 ttagctagtt ggtagggtaa aggcctacca aggcgacgat acatagccga cctgagaggg
      541 tgaacggcca cactgggact gagacacggc ccagactcct acgggaggca gcagtaggga
      601 atcttcggca atggggggaa ccctgaccga gcaacgccgc gtgagtgaag aaggttttcg
      661 gatcgtaaag ctctgttgtt agagaagaac agtgatggga gtggaaagtc catcatgtga
      721 cggtaactaa ccagaaaggg acggctaact acgtgccagc agccgcggta atacgtaggt
      781 cccgagcgtt gtccggattt attgggcgta aagcgagcgc aggcggtttg ataagtctga
      841 agttaaaggc agtggcttaa ccattgtatg ctttggaaac tgttaaactt gagtgcagaa
      901 ggggagagtg gaattccatg tgtagcggtg aaatgcgtag atatatggag gaacaccggt
      961 ggcgaaagcg gctctctggt ctgtaactga cgctgaggct cgaaagcgtg gggagcaaac
     1021 aggattagat accctggtag tccacgccgt aaacgctgag tgctaggtgt taggcccttt
     1081 ccggggctta gtgccggagc taacgcatta agcactccgc ctggggagta cgaccgcaag
     1141 gttgaaactc aaaggaattg acgggggccc gcacaagcgg tggagcatgt ggtttaattc
     1201 gaagcaacgc gaagaacctt accaggtctt gacatcccga tgctattctt agagataaga
     1261 agttacttcg gtacattgga gacaggtggt gcatggttgt cgtcagctcg tgtcgtgaga
     1321 tgttgggtta agtcccgcaa cgagcgcaac ccttattgtt agttgccatc attaagttgg
     1381 gcactctagc gagactgccg gtaataaacc ggaggaaggt ggggatgacg tcaaatcatc
     1441 atgcccctta tgacctgggc tacacacgtg ctacaatggt tggtacaacg agtcgcaagc
     1501 cggtgacggc aagctaatct ctgaaagcca atctcagttc ggattgtagg ctgcaactcg
     1561 cctacatgaa gtcggaatcg ctagtaatcg cggatcagca cgccgcggtg aatacgttcc
     1621 cgggccttgt acacaccgcc cgtcacacca cgagagtttg taacacccga agtcggtgag
     1681 gtaaccgtta aggagccagc cgcctaaggt gggatagatg attggggtga agtcgtaaca
     1741 aggtagccgt atcggaaggt gcggctggat cacctccttt ctaaggaaaa aggaagcacg
     1801 tttagcgtct tatttagttt tgagaggtct tgaaataagt catgagaacg ttaagaaacc
     1861 cgtatgacaa tagggaactg acgcagagtc gtaggactca aggaagtgat tctttttcac
     1921 tagggtttta gttcgaatac agtttggctt catacagacc attgataaga gtatacatat
     1981 acaagtacat ttatagtgta cggggcctta gctcagctgg gagagcgcct gctttgcacg
     2041 caggaggtca gcggttcgat cccgctaggc tccattatct aggatacaaa gagaagtttg
     2101 ggttacctaa ttttctgtat tctaagatat ataagatata gttcaagtaa ttgaacacga
     2161 cctcattttt taggaaaaaa gataaatctc ctcgtgtgta aagcacacat cgtcgatttc
     2221 ctatttttct acaaaaatgc ccaacaagtt gggacggtct tagtatctta atcttgtcca
     2281 ttgaaaattg aataactata tcatattccg caatcaaaaa agattgtaag aaagtaacaa
     2341 gaaataaacc gaaacgctgt gataacgagt ttaaaaaata aggttaagtt aataagggcg
     2401 cacggtggat gccttggcac tagaagccga agaaggacgt gacaaacgac gaaatgcttt
     2461 ggggagctgt aagtaagcaa agatccagag atgtccgaat gggggaaccc actagctaat
     2521 ggctagtatc cataactgtt aaggttatga gaaggaagac gcagtgaact gaaacatcta
     2581 agtagctgca ggaagagaaa gcaaacgcga ttgcctgagt agcggcgagc gaaaaggcag
     2641 gagggcaaac cgaagagttt actcttcggg gttgtaggac tgcgctgtgg gacgacaaga
     2701 ttatagaaga aggccttggg aagggtcgcc aaagagagta atagcctcgt attcgaaata
     2761 gtctttaacc ctagcagtat cctgagtacg gcgagacacg aggaatctcg tcggaatctg
     2821 ggaggaccat ctcctaaccc taaatactca ctagtgaccg atagtgaacc agtaccgtga
     2881 gggaaaggtg aaaagcaccc cgggagggga gtgaaagaga acctgaaacc gtgtgcctac
     2941 aagaagttcg agcccgttaa tgggtgagag cgtgcctttt gtagaatgaa ccggcgagtt
     3001 acgtttatgt gcgaggttaa gttgaagaga cggagccgaa gggaaaccga gtcttaatag
     3061 ggcgtaagta cgtggacgta gacccgaaac catgtgacct acccatgagc aggttgaagg
     3121 tgcggtaaga cgcactggag gaccgaacca gggcacgttg aaaagtgctt ggatgacttg
     3181 tgggtagcgg agaaattcca aacgaacttg gagatagctg gttctctccg aaatagcttt
     3241 agggctagcg tcgatatgaa gtctcttgga ggtagagcac tgtttgggtg aggggtccat
     3301 cccggattac caatctcaga taaactccga atgccaatga gatatgatcg gcagtcagac
     3361 tgcgagtgct aagatccgta gtcgaaaggg aaacagccca gaccaccagc taaggtcccc
     3421 aaataactgt taagtggaaa aggatgtggg gttgcacaga caactaggat gttagcttag
     3481 aagcagctat tcattcaaag agtgcgtaat agctcactag tcgagtgacc ctgcgccgaa
     3541 aatgtaccgg ggctaaaaca gtttaccgaa gctgtggatt accgttaagg taatggtagg
     3601 agagcgttct atgtgtgatg aaggtatact gtgaagagtg ctggaacgca tagaagtgag
     3661 aatgccggta tgagtagcga aagacaggtg agaatcctgt ccaccgtaag actaaggatt
     3721 ccaggggaag gctcgtccgc cctgggttag tcgggaccta aggagagacc gaagggtgta
     3781 tccgatggac aacaggttga tattcctgta ctagagtata tagtgatgga gggacgcagt
     3841 aggctaacta aaccggacga ctggaagagt ccggctaagc agtgaggtgt gatgtgagtc
     3901 aaatgcttac atctataaca ttgagctgtg aaggggagcg aagttaagta gcgaagttag
     3961 agacgtcaca ctgccaagaa aagcttctag cgatacgtat actctacccg taccgcaaac
     4021 cgacacaggt agtcgaggcg agtagcctca ggtgatcgag agaactctcg ttaaggaact
     4081 cggcaaaatg gccccgtaac ttcgggagaa ggggcgctga ctgaaggtca gccgcagtga
     4141 ataggcccaa gcaactgttt atcaaaaaca cagctctctg ctaaatcgta agatgatgta
     4201 tagggggtga cgcctgcccg gtgctggaag gttaagagga gtgcttagcg caagcgaagg
     4261 tatgaattga agccccagta aacggcggcc gtaactataa cggtcctaag gtagcgaaat
     4321 tccttgtcgg gtaagttccg acccgcacga aaggcgtaat gatttgggca ctgtctcaac
     4381 gagagactcg gtgaaatttt agtacctgtg aagatgcagg ttacccgcga caggacggaa
     4441 agaccccatg gagctttact gcagtttgat attgagtatc tgtaccacat gtacaggata
     4501 ggtaggagcc atagaagtcg ggacgccagt ttcgatggag gcgatgttgg gatactaccc
     4561 ttgtgttatg gctactctaa cccggatagg tgatccctat cggagacagt gtctgacggg
     4621 cagtttgact ggggcggtcg cctcctaaaa tgtaacggag gcgcccaaag gttccctcag
     4681 attggttgga aatcaatcgc agagtgtaaa ggtataaggg agcttgactg cgagagcaac
     4741 acctcgagca gggacgaaag tcgggcttag tgatccggtg gtaccgtatg gaagggccat
     4801 cgctcaacgg ataaaagcta ccctggggat aacaggctta tctcccccaa gagttcacat
     4861 cgacggggag gtttggcacc tcgatgtcgg ctcgtcgcat cctggggctg tagtcggtcc
     4921 caagggttgg gctgttcgcc cattaaagcg gcacgcgagc tgggttcaga acgtcgtgag
     4981 acagttcggt ccctatccgt cgcgggcgta ggaaatttga gaggatctgc tcctagtacg
     5041 agaggaccag agtggactta ccgctggtgt accagttgtc tcgccagagg catagctggg
     5101 tagctatgta gggaagggat aagcgctgaa agcatctaag tgcgaagccc tcctcaagat
     5161 gagatttccc ataacgttaa gttagtaaga gccctgagag atgatcaggt agataggtta
     5221 ggagtggacg tgtggtgaca catggagcgg actaatacta atagctcgag gacttatcca
     5281 aaagatgaaa ccagtcgcta ttgacagctt aaggaattct tgttagacta tagttattca
     5341 attttgagtg gagaagactc gtaagttaag tgacgatagc ctaggagata cacctgtacc
     5401 catgccgaac acagtagtta agccctagaa cgcctgaagt agttgggggt tgccccctgt
     5461 gagatacg
//
LOCUS       DARYYD010000092         5325 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.093, whole genome shotgun sequence.
ACCESSION   DARYYD010000092 DARYYD010000000
VERSION     DARYYD010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5325
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.093"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(150..389)
                     /locus_tag="TV188_001873"
     CDS             complement(150..389)
                     /locus_tag="TV188_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEL1535191.1"
                     /translation="MAQQRRGGFKRRKKVDFIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPYVNED"
     gene            complement(548..1036)
                     /locus_tag="TV188_001874"
     CDS             complement(548..1036)
                     /locus_tag="TV188_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEL1535192.1"
                     /translation="MINNVVLVGRMTKDAELRYTPSQVAVATFTLAVNRAFKSQNGER
                     EADFINCVIWRQQAENLANWAKKGALIGITGRIQTRNYENQQGQRVYVTEVVADNFQM
                     LESRATREANSSGSYGGGFNSSPATNSYSAPAQQTPNFGRDGSPFGGSNPMDISDDDL
                     PF"
     gene            complement(1055..1345)
                     /locus_tag="TV188_001875"
     CDS             complement(1055..1345)
                     /locus_tag="TV188_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEL1535193.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATIVESKDWE
                     KRRLAYEINDFREGLYHIVNLEATDAVALNEFDRLSKINGDILRHMIVKLDA"
     gene            2721..3869
                     /gene="mutY"
                     /locus_tag="TV188_001876"
     CDS             2721..3869
                     /gene="mutY"
                     /locus_tag="TV188_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEL1535194.1"
                     /translation="MIDLNDYGITMWDQDTIASFRRTLLAWYDQEKRDLPWRRTKDPY
                     HIWVSEIMLQQTQVVTVIPYYERFLDWFPTVEALACADEERLLKAWEGLGYYSRVRNM
                     QKAAQQIMTDFGGIFPSSHADITKLKGIGPYTAGAISSIAFDLPEPAVDGNVMRVMAR
                     LFEINYDIGDPKNRKIFQAVMEVLIDPERPGDFNQALMDLGTDIEAAKNPRPDESPVR
                     FFCAAYRHGTYDKYPIKEPKKKPRPIQVQAFVIRDSKGRLLLEKNTQGRLLGGFWAFP
                     LIETKLVSQQLTLFEDSPIVLETMSQTTLFEERYGLMPIWSQATFPQVKHTFSHQKWT
                     IELCEGFTDSMPLAPDRELVWVAIEDMAAYPMATPQKKMLEAYLKKQS"
     gene            4640..>5325
                     /locus_tag="TV188_001877"
     CDS             4640..>5325
                     /locus_tag="TV188_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface-anchored protein"
                     /protein_id="HEL1535195.1"
                     /translation="MNKKSARRRRKNLITKLAMTSALTLGVGAATTLAGQTEVRADNI
                     LRLDMTDKEAVEKFANELKNEVHKNYRGSNTWQKLTLILNGYQNLREQIETELKNSEQ
                     KVKELNDKVNSETQGKQELQNQLEKEKEELETLKKELEAEKAKGTGETEKLQKEIEAK
                     NAMISDLQKQLEETKQRVQEFEAEVGKLMAEKADLQTKLNEQEQLNAKLQKEIEDLKA
                     QIEKLKHCQDT"
BASE COUNT         1622 a         1165 c         1062 g         1476 t
ORIGIN      
        1 cttagatgag gagtttttct ttagccctat gcttcatcaa acaccaccag ataccacact
       61 ctcaatcaga tcacaggcta aggcttgacg acgctgctca gctgacttca gaccacataa
      121 aaaacagccc ttaaggactg tttcagatat tagtcttcgt ttacgtaagg cataagtgcc
      181 ataacacgag cacgtttgat agctgttgtt actttacgtt ggtttttagc tgatgttcct
      241 gttacacgac gaggaaggat tttcccacgt tctgaaacga aacggctaag aagctcagta
      301 tctttgtaat caacatattc aattttgtta gctgcgataa agtcaacttt tttacggcgc
      361 ttgaatccgc cacgacgttg ttgagccatg tgttatctcc tttatattat tcacatgata
      421 aatttgctgc ctaataagca aaccgacgcc agaaagaggc ctcaatcttt tgtgcttgaa
      481 agcaactcct ctgtctccca agctaccagc aaatctatgc aattcatgtc agtccacttt
      541 ccattgctta gaatggaaga tcgtcatctg aaatatccat tggatttgag ccgccaaatg
      601 gacttccatc tctgccaaag ttaggtgttt gctgagcagg cgctgaatag ctattggttg
      661 ccggtgagct attaaaacca ccaccatatg agccagacga gttcgcctca cgtgtagcac
      721 gactttccag catttggaaa ttatctgcaa caacctcggt tacatacaca cgctgcccct
      781 gttggttttc gtagttacga gtctgaatac gtcccgtaat cccaatcaag gcaccctttt
      841 tagcccagtt agctaaattt tcagcttgct gacgccagat cacacagtta atgaaatccg
      901 cttcgcgctc accattttgg ctcttaaagg cgcgattaac agcaagtgta aacgtagcaa
      961 ctgccacctg acttggagtg tatcgaagct ctgcgtcctt ggtcatacga ccaactagta
     1021 ctacattatt aatcataaac tacctacttt gcaattaagc gtcaagctta acgatcatgt
     1081 gacgaagaat gtcaccgttg atttttgaca gacggtcaaa ctcattaaga gctacagcgt
     1141 cagtcgcttc aaggtttacg atatggtaaa ggccttcgcg gaaatcattg atttcgtatg
     1201 caagacgacg cttttcccaa tcttttgatt caacaatagt tgcaccattg tcagtcaaga
     1261 tagagtcaaa acgtgctacc aaagcgtttt tagcttcttc ttcaatgttt ggacgaatga
     1321 tataaagaat ttcgtattta gccattgata gtttcctcct tttggtctaa tgactcgcta
     1381 cccttgtaac gagtaagtga ggtatgctca cagattaaca gtatacaata aacaaaggta
     1441 aaaagcaagc aaaatgttga cctttctgtt gaataaaaga ccttcttaga tcccttcgta
     1501 gctccataaa aagcaaagcc acttctatag aaatgacctt tagtcacctg acttgcaggt
     1561 cttagtggca aggtcaaatc cagacaccag caaaaaggac acccaaccgg gtgtccttat
     1621 catgtcttga gtgctattct cccttctatc tgccatttaa taaggagtca cctgtcaatt
     1681 gttcctctaa agaggaacac atacttatct gtctaatcag tcgtctcctt tctgtttaac
     1741 aaaatgaacg gttattaaaa gaatatgact gttcttgagt ttcgtttgtt agcactgtgc
     1801 tattttggct tacattggac tcactccttc agctattttt tgctgtcgtg ctcaatgtct
     1861 ccgtttttat atcttgcgat gtacataaga ccctcctatt agaaaagctc actagctatc
     1921 tgatgatagc tacctttcaa ataagctcaa tcctttaccc tgagtgccaa taacaatatc
     1981 aaggacgact agtgacacag caactagtct ccatttttat agcgtccttt attgaatctt
     2041 agcatagcat acgtcctttc aataacggga atttcaagct tatactgttt agagcgctcc
     2101 tttggccaaa gctggtaatc tcgataagcc ttcacatgtg atcacatatt aaattgtaaa
     2161 attggttttg cctaccgttt gttggagctc ttaatctcca tttttgtacc gcgcgacatg
     2221 tcttgttatc atcagatatc ctcctataac tccagtgtca tcggtcgtcc ttatctacat
     2281 ctttattata atgtaagcgg ttactaaagt caagcttttt gctccttttt tgataacata
     2341 tcagcaacta aaaccccacg ataggacaca agccttcagc aaagactgag aaccttttta
     2401 tacttgtcat ttacgttcaa gtgcctttgt caatacctca gagtcattaa ccttttcgcg
     2461 gtcagctaat ctaaccaacc actctgaaac ggtaacagtt ttacgaacag ctttattatt
     2521 tttgataaat ggtgttgaat cagcttgtag gaactggtaa attcagacca caatcaatat
     2581 aagcagcaag aacattttct aacatgtcat gagcagttgt cacagcctct ttataaggta
     2641 taaatcacaa agcatgcttt aacaaatcct atcggacgca gggttcaacc aattcagaca
     2701 atctgtgtta caataggatt atgatagatt taaatgatta tggcattacc atgtgggatc
     2761 aagataccat tgcctccttt cgtcgtacgc tgctagcttg gtacgatcag gaaaagcgag
     2821 acctgccttg gcgtcgcaca aaggaccctt atcatatctg ggtctcagag atcatgctcc
     2881 agcaaacgca ggtcgttacc gttattcctt attacgagcg atttttggat tggtttccaa
     2941 cggtagaggc cctcgcctgc gctgacgaag agcgcttact caaggcttgg gagggactgg
     3001 gctactactc tcgtgtacgc aatatgcaaa aggctgcgca gcaaatcatg actgactttg
     3061 gcgggatttt cccaagctca cacgctgata ttactaagtt aaagggcatt ggcccttata
     3121 cagctggcgc tatctcaagc attgcctttg atctgcctga gcctgcggtt gatggcaatg
     3181 tcatgcgagt catggccaga ctgtttgaga ttaattacga tattggagac cctaagaacc
     3241 gcaagatttt tcaggctgtt atggaggtgc ttatcgatcc ggagcgaccc ggagatttca
     3301 atcaagcctt gatggatctg gggactgata ttgaagcggc taaaaatccc agacctgacg
     3361 agtctcctgt gcgctttttc tgtgcagcct accgacatgg tacctatgac aaatacccca
     3421 tcaaggagcc aaagaaaaag ccccggccta ttcaggtgca ggcctttgtg attcgtgaca
     3481 gcaaggggcg gcttttgctc gaaaaaaata cccaagggcg cttgctaggt ggcttttggg
     3541 cctttcctct gatagagacc aagcttgtca gtcaacaact gaccctcttt gaggacagtc
     3601 ctatcgtgct tgagaccatg tctcagacaa ccctttttga ggagcgttac gggcttatgc
     3661 ctatctggtc tcaagctacc tttcctcagg tcaagcatac ctttagccac caaaaatgga
     3721 ccattgagct ttgcgagggc ttcacagaca gcatgcccct agcccctgac agagaacttg
     3781 tctgggtcgc aatagaggat atggctgctt acccaatggc aaccccacaa aagaaaatgc
     3841 tagaagccta cctaaaaaaa caaagctaag cggctcatag ctgtcagata aggtccttaa
     3901 ggcagagctt tagggacttt tttgcttgcc caaggagctt acttgtagcc tacttggtct
     3961 gatcagacaa gaaaaactcg atttcttgta acaaagtcag acgattaccc ttttcattaa
     4021 aaaaacgaaa ctacggagac aaattgggac actgctatgt cttgtcgtca gctgtcgtgc
     4081 tacactggcc ttagaaacta agcacagcca aaagctgtga aaactataac tatattatgg
     4141 aggagaaaac acaatgaagc tgacaaatgc cctatgccta gtagccgcta ctgcagccct
     4201 agccctagca ccaatcaaca caagcactgg acaaactaat accgttttgg caagtcaaaa
     4261 aagtacagga cattgtactc atactagaag tggatggttt aaatgccctg atggaggatc
     4321 atattacgac gaaagttacg atacacattc atcatggtta atttggcttt atggtgcttt
     4381 ttactctgca tgggaaatta taactagttg gttcaaataa attagtaaag caggtcaggt
     4441 tattatcggc ctgcttttct taatcagcct tgctaatgcc tgctgaattg ccagaaatca
     4501 gacaattagc cttttcatta aaaccaaaaa ccgaacgaat ctaggagaga aagtagcgga
     4561 caactatttc tctatcttga tgactgtgtt aaaatatctt cagtcaaaat taatatgtct
     4621 atcattaaag gagagagaaa tgaacaaaaa atcagcaaga cgcaggcgta agaatcttat
     4681 tacgaagctt gcgatgacaa gtgccttaac cctgggtgta ggcgcagcga ctaccctagc
     4741 aggacaaaca gaagtacggg ctgataatat cttacgctta gatatgacag ataaagaagc
     4801 agttgaaaaa ttcgctaacg agcttaaaaa tgaagtccat aaaaactatc gtggtagtaa
     4861 tacttggcaa aagcttaccc ttatacttaa tggttatcaa aaccttagag aacaaataga
     4921 gaccgagcta aaaaatagtg aacaaaaagt aaaagagctt aatgataagg ttaatagtga
     4981 aactcaagga aaacaagagt tacagaatca gcttgagaaa gaaaaagaag agttagaaac
     5041 actaaaaaaa gagcttgaag ctgagaaggc taaaggaact ggagaaacag agaagcttca
     5101 aaaggaaatt gaagcaaaaa atgcaatgat ttctgaccta caaaaacagc ttgaggaaac
     5161 taagcaaagg gttcaagagt ttgaagctga agtaggtaaa ttaatggccg aaaaggcaga
     5221 cctacaaaca aaattaaatg aacaagagca gcttaacgct aagcttcaaa aagaaattga
     5281 agacttaaag gctcagattg aaaagcttaa gcactgtcaa gatac
//
LOCUS       DARYYD010000093         4465 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.094, whole genome shotgun sequence.
ACCESSION   DARYYD010000093 DARYYD010000000
VERSION     DARYYD010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4465
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.094"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            20..796
                     /gene="recX"
                     /locus_tag="TV188_001878"
     CDS             20..796
                     /gene="recX"
                     /locus_tag="TV188_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEL1535196.1"
                     /translation="MKISQIEKKKHLYLIKLDNGDSLTVTEDTIVTFMLSKHMVIDSQ
                     QWEDIKSFAQFSYGKSKALGFIAFQQRSQKQVQDYLLKHQISPDLIPSIIDSLKQGKW
                     IDDQQYVDTYIRQNSLTGDKGPLLLKQKLMLKGIASQLIEPVLAQTDFSSIAQKAAEK
                     IYQKYQHKLPSKALTDKIIQGLLNKGFSYDLAKGIVSQLSLEQDSQHIEDLLDQEFDK
                     LLRKYSRRYDGYQLKQKLYQALYRKGYDSDDITTKLNDYF"
     gene            1029..1562
                     /locus_tag="TV188_001879"
     CDS             1029..1562
                     /locus_tag="TV188_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002949762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEL1535197.1"
                     /translation="MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYLMDAEALKYI
                     DYDLDVKVFADGEKRLLDVDEYEMHKQEMHYSPNLDFILKENVKLLVDWINKEKGPFS
                     KAYVSIWYKRYLELKNR"
     gene            1812..2123
                     /locus_tag="TV188_001880"
     CDS             1812..2123
                     /locus_tag="TV188_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEL1535198.1"
                     /translation="MAFQATKGRYASFGVAVSLPPELIDTFWEIIDHYLKGVFPLNTV
                     LTFRLIKNKKNLSYEYIDQQAGLRIVFDYNTPFNAFYPKTLYIVNQQGIETILLPHEM
                     Y"
     gene            3264..4465
                     /locus_tag="TV188_001881"
                     /pseudo
     CDS             3264..4465
                     /locus_tag="TV188_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISSeq1 family transposase"
BASE COUNT         1467 a          975 c          786 g         1237 t
ORIGIN      
        1 aaaacattat aatgagggta tgaaaatcag tcaaattgaa aagaaaaagc atttatacct
       61 cattaagcta gacaatggtg atagcctaac ggtcacagaa gatacgattg tcacatttat
      121 gctaagtaag cacatggtca tagacagcca acaatgggag gacatcaaaa gcttcgcaca
      181 attctcatat ggtaaaagca aggccttagg ttttattgcc ttccaacaaa ggagccaaaa
      241 gcaagtccaa gattacctgc taaagcatca gattagtcct gatctcattc caagcattat
      301 tgatagccta aaacaaggca aatggattga tgatcagcaa tacgttgaca cctatatacg
      361 ccaaaatagc cttactggag acaagggacc attacttctc aagcaaaagc taatgctcaa
      421 gggaatagcc tcacaactca ttgagcctgt cctagcacag actgattttt cctctatagc
      481 acaaaaggct gctgaaaaaa tctaccagaa atatcaacac aaattgccaa gtaaggcctt
      541 gaccgataaa atcatacaag gacttcttaa caagggcttt tcctatgacc ttgccaaagg
      601 cattgtcagt caactaagcc ttgagcagga tagtcagcac atcgaagacc tgcttgatca
      661 ggaattcgac aagctattac gaaaatacag tcgtcgctat gatggctatc agttgaagca
      721 aaagctttac caagcccttt accgcaaggg ctatgacagt gatgatatta ccactaagct
      781 aaatgactat ttctaattct accaaggctg ctgcaccgat ttgacgcaaa agcttttagt
      841 cagcaacaaa gtagtcctat tatgatcctg tagctttgat aatggtttag ctagctcctc
      901 aactgaacat cagatttcta aaaacttctt taagcatttg tcagatcata ttgtccaaaa
      961 cagtgattta ttttctcaat tatggtaaac tatagaggat aagtttaatt gtagaaagtt
     1021 ggtaaggcat gaaattacct aaagaaggcg actttattac aattcaaagt tataagcatg
     1081 atggtagatt gcaccgaacc tggcgcgata ctatggtact aaaaacaact gaaaatgctc
     1141 tgattggagt taatgatcac acacttgtta ctgaaagcga cggcaggcga tgggtgacac
     1201 gagagcctgc gattgtttat tttcataaaa aatactggtt caatattata gcaatgattc
     1261 gagataatgg tgtttcctat tattgcaacc ttgcaagtcc atacctgatg gacgcagaag
     1321 cgctcaagta tattgactat gatcttgatg tcaaagtctt tgcagatggt gaaaagagat
     1381 tgcttgatgt agacgaatat gaaatgcaca agcaagaaat gcattattca cctaatctgg
     1441 attttatttt aaaagagaat gtcaagctat tagtcgactg gatcaataaa gaaaaaggac
     1501 cattttcaaa agcctatgtc agtatttggt acaaacgtta tcttgaactg aagaatcgtt
     1561 agtcgttgtc tagcactcca ccgagggtgc tttatttaat cgctagtata gtatcacagc
     1621 tgtaaactgg actggcactt gcaatctatc agcatttgtt gtcaaattca tatcattaac
     1681 cactatagct tggcacaagc acagacagcc tataacacca agtagcaatc agtatttatc
     1741 atcagctgcc tagctagatc aggcattcaa atgacctcat tataacacca taacaataga
     1801 aaggattgac aatggcattt caagcaacaa aaggacgata cgcaagcttt ggcgttgcag
     1861 tcagccttcc acctgagctg attgatacct tctgggaaat cattgaccat tacctaaaag
     1921 gggtgtttcc cctcaatact gttctcacct tcaggctaat taaaaataaa aaaaaccttt
     1981 cttatgagta cattgatcaa caagctgggc ttcggattgt ttttgactat aacacaccat
     2041 ttaacgcctt ttaccccaaa acgctctata tcgtaaacca gcaaggaatt gaaacgattt
     2101 tattgcctca cgagatgtat tgataagacc tcggacatca gctataaagt ccttaccatt
     2161 cagttgtagc tcatcacatc tgctacaagc accaacatga gataatcttg tgtctttatc
     2221 ctagctctga atgctgtata gatattcagt cagccagata catagcaata aactaagctc
     2281 atgccggtag aaatagtcct aacatgagct tgacagtttt ttcattctgt aaatcattgc
     2341 taagcaaaca catcacctaa gccctatttc ctattctggg aaatggaaat cttgatagaa
     2401 catcccaata gtcccatcat attgagctat atctataggg tctgacattt tgatatgtta
     2461 tcatctcatt ttacgacaat cactataggc tttatgacaa ttggcatcat tgtcataacg
     2521 attaaattct atatgaccaa atggctagta ggaagctaat tgctttgtgt tagcctcaca
     2581 taggatcttc acataccccg taatcttaaa agtagtttta actgcacaaa acttatagaa
     2641 cctaaaaatc aacaaacaca ctttaaagta caaaaacttt gccctccctc aaaaagctct
     2701 ataatctctg tagtcggtaa gcccactgtg gaaattatag tttttttaat tgtacaaaaa
     2761 caagcccata tgacttatca tgaaatgcaa tcaaaccatc attagaaaga ctcataggaa
     2821 caccttaagc attactcagc atttaaaaaa caatatccaa ccgttgactg ttctaaaagc
     2881 tcacccccac atcgttatca atcctaagct tgattattca gttctcttat gccctcacta
     2941 caaaggaaac atgagcaaac aagacttcca aaaagcctct aaaatcccta tcttcgattg
     3001 ccaaagcttt ccaacactgc ttcaactcaa aaaacactgc tttcagtgga aagccagttc
     3061 taaagtgagc cttgctcaaa ctccttttgg ttttaacatc acaaaaaaga gcaccaatct
     3121 ggtcctcttt agacgttagt taggctcaat aatttctgta gtgggtaagt ccactgcagg
     3181 ggttataggg ctttatgagt atcaaaaaag tcccatatga cctataatga aaagcgacta
     3241 aactatcatt tagaaagact catatggaac aatcacatgt tatcacacaa ctactgggaa
     3301 ttaaagaccc tcatatcaca ttctccaaag aaatacacga catgaaaact cataaggaat
     3361 tgaaagctgt ccttgactac gatgccccac cttgccctaa ctgccaaagt cagatgggca
     3421 agtacgactt ccaacgggaa tccaaggtcc cttttctcga ttgcgcaggc tacaagactt
     3481 tgattcgcct caaaaagcgc cgtttcaaat gtcagttttg cggaaaaatt actgtcgctg
     3541 agacttctct agtccctaaa aaccatcaaa taccaaccat cgtcaaacag aaggtggccc
     3601 agcttctcat cgagaaagtc tccatgaccg ctatcgctga tagactatcc atctccacct
     3661 caaccgtcat gcgaaagctc aacgagttca cgttcaagtc tcatttgact tatttacccg
     3721 aacatatgtc ctgggatgaa tatgccttta agaagggcaa gatgagcttt attgctcagg
     3781 actttgacac caacaacatc atcgctattt tggatggacg gacgaaagct gtcattcgca
     3841 accacttcct gagatatcct cggcaggtca gaaacgacgt taaactcatc accatggata
     3901 tgtttacccc ctattacaac ctggctaaga tgcttttccc aaacgcttag attgtccttg
     3961 atcgtttcca cattgtgcaa catttgggac gtgccatgaa ccgtatccgt actcaaatca
     4021 tgaactcttt tgatcgaaaa tcccacgaat acaaggcttt gaaacgttac tggaagctga
     4081 ttcaacaaga tagtagcaaa cttagtgaca agcgttttta ccgcccgact tttcgcatgc
     4141 atttgacaaa caaggaggtg gtcgagcgtc ttttgagcta ctctgacgag cttagaaagc
     4201 attatgacct ttatcagctt ctgctttttc acttccagga aaagcaagct gaccactttt
     4261 tcggcctgat tgaggagcag atagacagta gcaatcctct ctttcagacc gttttcaaga
     4321 cctttttgaa agacagagac aagattgaga acgcactgga tttgccttat tctaacgcta
     4381 aactggaggc taccaataat ctcatcaaag tcatcaagcg caatgctttt ggatttcgga
     4441 actttgaaaa ctttaaaaga cggat
//
LOCUS       DARYYD010000094         4299 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.095, whole genome shotgun sequence.
ACCESSION   DARYYD010000094 DARYYD010000000
VERSION     DARYYD010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4299
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.095"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            104..286
                     /locus_tag="TV188_001882"
     CDS             104..286
                     /locus_tag="TV188_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1535199.1"
                     /translation="MLIYDEFKQAVDNGYITGDTVAIVRKNGQIFDYVLPHEEVRNGE
                     VVTDEKVEEVMRELDK"
     gene            484..873
                     /locus_tag="TV188_001883"
     CDS             484..873
                     /locus_tag="TV188_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEL1535200.1"
                     /translation="MFYLAVHDQFDKKSRLAEIAKSRAGVISIDHIDCYHGTQSYLSL
                     FGKNKAGNTIIVTIEEQSEQLLLSRPSNGISAKEAQEIAYHAGARTIEAVTFGIENHK
                     RIWEVAAQNGYYLIDFKTAKVIKKEVL"
     gene            870..2081
                     /locus_tag="TV188_001884"
     CDS             870..2081
                     /locus_tag="TV188_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEL1535201.1"
                     /translation="MTKLSRRVLAMEESVTLAAGARAKALKAQGRDILSLTLGEPDFI
                     TPQHIQEKAIEAITTGKASFYTVASGLPELKDAIADYMARSYGYIPTRQEIVVGTGAK
                     YVLYAFFMAVLNPGDQVLIPTPYWVSYADQIKMVDGVPVFVQGLEENQFKVTVEQLEA
                     ARTDQTKVVLINSPSNPTGMIYSRQELEAIGNWAVQHDILILADDIYGALVYNGNQFT
                     PISALSEAIRRQTITVNGVAKSYAMTGWRLGFAVGDTDIIAAMGKIIGQTTSNVTTAS
                     QYAAIEAFGGDQTSVEEMRQAFEERLNTIYPLLNQVPGFEAIKPQGAFYFFPNVKKAM
                     EMKGFTDVTAFTDAILEEVGLAVVSGAGFGAPENIRLSYATDLATLKEAIRRLNQFMT
                     TDSSHDNKENE"
     gene            2094..3440
                     /gene="asnS"
                     /locus_tag="TV188_001885"
     CDS             2094..3440
                     /gene="asnS"
                     /locus_tag="TV188_001885"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEL1535202.1"
                     /translation="MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSA
                     FFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITD
                     LEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
                     IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYPFLSHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTE
                     LLKRYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSPHETWISNYFGVPT
                     FVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAE
                     GLNPEDYDFYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP"
     gene            3740..>4299
                     /locus_tag="TV188_001886"
     CDS             3740..>4299
                     /locus_tag="TV188_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HEL1535203.1"
                     /translation="MMNRKKHTKLIRHYSICSAVAVLAAVSLGTGQDVQASEPNPYPD
                     VRRFLDEKYDGDVDKLSKQLQGYFGSLREYIEFELKNGKQGPAGPQGPKGDKGDPGEP
                     GPQGPVGPAGPKGDRGLDGRRGPAGQQGEAGPVGPQGPQGEQGPKGDRGEQGPKGERG
                     EQGPKGERGEQGPKGDRGEQGPKGERG"
BASE COUNT         1254 a          897 c         1072 g         1076 t
ORIGIN      
        1 tcacacacat gtattcacac attggcatat ccgttataac ggacttgtta aaattagtcc
       61 attaaactag actttttacg aataataagg taggaggtaa tttatgctaa tatacgacga
      121 gtttaagcag gcagttgata acggatatat cacaggagac acagtagcga ttgtgcgcaa
      181 aaacggacag atttttgatt atgtgttgcc gcatgaggaa gtaaggaacg gggaggttgt
      241 gacagacgaa aaagtggaag aggtgatgag agaattagac aaataaaaaa gacctcgtcc
      301 agaagtcggg gaattgtcgg ggacaacgtt tgtaaatgtt tctattccaa cataaaacat
      361 tttttgatat aataggaagg atcatatgca aaggagctga aattggacaa gcacaaaagg
      421 ctcaaaacag ttttatatca atgtgccagc ttggtcgtac tgctttgtct tggagtgatg
      481 agcatgtttt atcttgctgt tcatgatcaa tttgacaaga aatcaaggtt agccgagata
      541 gcaaaatcaa gagctggtgt catctcaatt gatcatattg attgctatca tggcactcag
      601 agctacctca gtctttttgg aaaaaacaag gcaggcaata ccatcatcgt cacaatagag
      661 gagcaatcag agcagctctt gcttagtcgc cctagcaatg gcattagtgc taaggaagca
      721 caggaaattg cctaccatgc cggagcaagg actattgaag cagtgacatt tgggattgaa
      781 aaccacaaga ggatttggga ggtggctgct caaaacggct actatctgat tgatttcaaa
      841 accgcaaaag tgatcaaaaa ggaggtttta tgaccaagct atcaaggcgc gtgttagcaa
      901 tggaagaaag cgtcacccta gcagcaggtg ctagagcaaa ggcactaaag gctcagggac
      961 gcgatatttt aagcctaact ctgggagagc cagattttat aacaccgcag catatccaag
     1021 aaaaggccat tgaggccatc accactggta aggcaagctt ttacactgtt gcttcggggt
     1081 tgccagagct caaggacgcc attgctgatt acatggcacg atcctatggt tatattccta
     1141 ccagacagga gattgtagtg gggacaggcg ccaaatacgt tttgtatgcc tttttcatgg
     1201 ctgttttaaa tcctggtgat caggtgttga ttccgactcc ttattgggtt tcttatgctg
     1261 atcagattaa aatggtagac ggggtaccgg tctttgtaca gggcttggag gaaaatcaat
     1321 ttaaggtcac agtagagcag ctagaggctg ccagaactga tcaaacaaag gttgttttga
     1381 tcaattctcc gtccaatcca actggcatga tttacagccg acaggagctt gaagccattg
     1441 gcaattgggc tgttcagcat gatattctga tcctggcaga tgatatctat ggtgcattgg
     1501 tctacaatgg caatcaattt actccaatat cagccttatc agaggctatt cgtagacaga
     1561 ccattactgt aaatggcgtt gccaagagct atgcgatgac aggctggcgt ttgggctttg
     1621 cggtcggaga cactgatatt atcgctgcta tgggtaagat tatcgggcaa accacctcta
     1681 atgtgacaac agcgtcccaa tatgcagcga ttgaggcctt tggcggtgac caaacgtcag
     1741 ttgaggagat gagacaggcc tttgaagagc gcctcaatac catttatccc ctgctcaatc
     1801 aagttcctgg ctttgaggct attaagcccc aaggagcctt ttatttcttt cccaatgtca
     1861 aaaaagctat ggagatgaag ggctttaccg atgtgacagc ctttactgat gcgatcctag
     1921 aagaggtagg actggctgtt gtcagcggag ctggctttgg tgctccagaa aatatcaggc
     1981 taagctatgc cactgatttg gcaaccctaa aagaagctat cagacgactc aatcagttca
     2041 tgacaactga cagcagccat gacaacaaag agaatgaata gaaaagagac attatgacca
     2101 aaaaatacgt ttccattatc gatgttaaag accatgtagg acaagaagtg acagttggtg
     2161 cttgggtcgc caacaagtca ggcaaaggga aaatagcctt tttgcaattg cgtgatggct
     2221 cagccttttt ccaggcagtt gcctttaagc caaacctgat ccaagccttt ggtgaggaag
     2281 caggagcagc taagtttgac acgattaggc atctcagcca agaaacctct gtcttagtaa
     2341 agggcattgt caaagaggac gctagatcaa aatttggcta tgagctagac attacggacc
     2401 tagaggttat tggggattcc aaggattatc caattactcc aaaggagcat gggacagact
     2461 ttctcatgga tcaccgtcac ctttggctgc gctctcgcag gcaggcagca atcatgcaaa
     2521 tccgtaatgc catcatctat gcttcctatg agttttttga tcaaaatggc tttatcaagt
     2581 ttgatagccc gattttatca ggcaatgctg ctgagaacac aacagagcta tttgagacag
     2641 attattttgg caatccagcc tttctcagcc aatcaggtca gctatacctt gaagctggta
     2701 tgatggcgct tggtcgcgtc tttgactttg gtccggtatt tcgtgccgaa aaatcaaaaa
     2761 cgcgccgcca tctgacagag ttttggatga tggacgcaga ataccccttc ttatcccatg
     2821 aggaatcctt agacctacag gaagcctatg ttaaggcgat gattcagggt gtgcttgatc
     2881 gtgctccaca ggcattggag cttctagagc gtgacacaga gctgctgaaa agatacattg
     2941 cagagccctt caagcgtgtc tcctacgacg atgcgatcag cctgcttcag gagcacagca
     3001 cagatgacga tgccgactat gagccaattc agcatggcga tgactttggc tcaccgcatg
     3061 aaacctggat ttccaattat tttggggtcc caacctttgt catcaactac ccagctagct
     3121 ttaaggcctt ttacatgaag ccggttcccg gcaatgaaga gcgcgtgcta tgtgcggacc
     3181 tgctagcacc agagggctac ggtgagatta tcggaggctc ggttcgtgag gataactatg
     3241 acaaattgtt ggcgaaaatc aaggctgaag gcctaaatcc tgaggattat gacttttacc
     3301 ttgaccttcg caaatatggc tcagtgccgc atgctggttt tggacttgga ctagagcgca
     3361 tggtgacctt tgttgcaggt accaagcaca ttcgtgaggc tattccattt ccacgcatgc
     3421 ttcatcgctt aaaaccataa tgaaccctat cagcgtccgc cattgggcgc ttttttgctg
     3481 cgctgagcag tacttagagc tcaagcctcc cagttagact tggcagagct gtggctcttt
     3541 gcttgagcta ttgtaggcaa aggtatcact ggatctgaaa acaacaaaat cagacaagtg
     3601 atatcaaaat taaaaaaaaa aaaaacgaaa cctaggagga tcggtgagct tattagtttg
     3661 gcactaatca tcattatgct ataattgtct tcacaaataa tttagaaata gctcatattt
     3721 ctatcattaa aggagagaga tgatgaatcg taaaaagcat accaaactca ttcgtcacta
     3781 cagtatctgc tcagcagtgg ctgtcctagc agcagttagc ttgggaacag gtcaggacgt
     3841 acaggcttcg gaacccaatc catatccaga tgtgaggcgt ttccttgatg agaagtacga
     3901 tggagatgtg gataaattat ctaaacaact tcaaggttat tttggtagtt taagagagta
     3961 tatagagttt gaacttaaaa atggcaaaca aggtcctgct ggccctcaag gcccaaaggg
     4021 tgataaagga gaccccggag agccaggtcc tcaaggtcca gtgggccccg ctggtccaaa
     4081 gggtgatcgt ggtttagacg gacgacgtgg cccagcaggt cagcaagggg aagccggccc
     4141 agttggtcct cagggtcctc aaggcgagca agggccaaaa ggcgaccgtg gcgaacaagg
     4201 accaaagggt gaacgcggtg agcaaggacc aaagggtgaa cgcggtgagc aagggccaaa
     4261 aggcgaccgt ggcgaacaag gaccaaaggg tgaacgcgg
//
LOCUS       DARYYD010000095         4222 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.096, whole genome shotgun sequence.
ACCESSION   DARYYD010000095 DARYYD010000000
VERSION     DARYYD010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4222
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.096"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            1..133
                     /locus_tag="TV188_001887"
                     /pseudo
     CDS             1..133
                     /locus_tag="TV188_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795769.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
     gene            415..1182
                     /locus_tag="TV188_001888"
     CDS             415..1182
                     /locus_tag="TV188_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HEL1535204.1"
                     /translation="MEQKLNHLAVGEFVLLLPEHLRSEEEHYKSVFEDDLTSRMSSQD
                     GRQQMIATVAYLESGQDRFVYNTTPISYQQFLKDPIIIVVTPQSTGPQSVMFWFDAVQ
                     NYVLFNQLSDAQELIQRQDIENWVSEMQSGYQNYITLLNNIQRERWIMLAGAVLGIAT
                     SILLFNTMNRLYFEEFRRAIVIKRIAGLRFLEIHRNYLLAQLGVFLLGFVASVFLQVE
                     IVIAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            1184..1816
                     /locus_tag="TV188_001889"
                     /pseudo
     CDS             1184..1816
                     /locus_tag="TV188_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            2409..3263
                     /gene="ylqF"
                     /locus_tag="TV188_001890"
     CDS             2409..3263
                     /gene="ylqF"
                     /locus_tag="TV188_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEL1535205.1"
                     /translation="MATIQWFPGHMSKARRQVQENIKHVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLMLLNKADLADNTHTKKWQQYYEKQGIKTLAINAKEQATVKRVTEAAK
                     ELMADKLRRLRERGIQKETLRTMIIGIPNAGKSTLMNRLAGKKIATVGNKPGVTKGQQ
                     WLKSNKELEILDTPGILWPKFEDELVGLKLALTGAIKDQLLPMDEVTIFGLNYFKKYY
                     PNRLLKRFKAIDLEADAPEIIMSLTRQLGFKEDYDRFYSLFIKDIRDGRLGQYTLDQV
                     GDDDSNDY"
     gene            3244..4026
                     /locus_tag="TV188_001891"
     CDS             3244..4026
                     /locus_tag="TV188_001891"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEL1535206.1"
                     /translation="MTAMTIKDIKARLEAVSSLSDPFFEELKADKRLGVQKAVSSRKR
                     ALEAILKEEARLEAMLTYEQALYQKGFQAIAGIDEVGRGPLAGPVVAACVILPKGCTI
                     KGLNDSKKIPKAKHEAIYQAIQKKALGIGLGIIDNHTIDRVNIYEATKLAMTAAINQL
                     EGSVSKPDYLLIDAMTLEVSIPQQAIIKGDASSMSIAAASIVAKVTRDRLMLDYDKAF
                     PGYGFAKNAGYGTKEHLQGLHQYGVTPIHRQSFEPIKSMILR"
BASE COUNT         1342 a          759 c          912 g         1209 t
ORIGIN      
        1 agctcaggag tttttattta aaacagttgg aatcccagga acaccaacaa tactatatct
       61 gaagaatggt caacctgttg ctggctgggc tggtggagga gtaacggctc aacagcttta
      121 taattatttt tattttgaga aacgtccaga atctccaaca aaagaagata acaagcaggc
      181 agaatcaact gaaaatatca ccgttgaaat gacagcattt aatagctcag aacagttaca
      241 agagcaagct aatctgaaaa acataggtgc tactcaagta ttgataacaa aggctaagac
      301 ttttccaaaa acttgacaac ttctacagaa tggcaagatt acagcccaaa tggcaatgtc
      361 cttattgtca caccgcaata cttggagcgt caaaacatcc ctgtagatac ggctattgaa
      421 caaaaactga atcacctcgc agtaggggaa tttgtcttgc tcttgcctga gcatctccgt
      481 tcagaggaag aacattacaa atctgttttt gaagacgact taactagtcg catgtctagt
      541 caagatggtc gacagcaaat gattgcgacg gtggcttatt tggaatcagg ccaagaccgt
      601 tttgtgtata atacgacacc tatttcctat caacagtttc tgaaagatcc gattatcatt
      661 gtcgtaacac cccagtcaac tggacctcag tccgtcatgt tttggtttga cgcggtacag
      721 aattatgtcc tctttaatca gttgtccgat gcccaggagc ttatccagag acaggacatt
      781 gaaaattggg tctcagaaat gcaatcagga taccagaact acatcacatt gttgaataat
      841 atccagaggg aacgttggat aatgcttgcg ggagctgtgc ttgggatagc aacctcaatc
      901 ttgttgttta acaccatgaa taggctctac tttgaagaat ttagacgtgc cattgtcatc
      961 aaacgtattg ctggactaag atttttagaa atccatcgga attacctcct ggctcaattg
     1021 ggtgtctttt tactcggatt tgttgcgagt gtattccttc aagtagagat agtgattgct
     1081 ttcttagtat tgttgctctt cactggccta tctcttttac aattacatgt tcaaatgcag
     1141 aaagaaaaca agatgtccat gcttgttttg aaaggaggtt aacatgattg aacttaaaca
     1201 agtgagtaaa tcttttggag aacgagagct attttctaat ctttcaatga catttgaggt
     1261 tggaaaagtc tatgctttga ttggttcaag cggtagcggg aaaacaacct tgatgaacat
     1321 gatggggaaa ttagaacctt atcatgggac tattttttac cgagacaaag acttagccag
     1381 ctataaatct agtgattttt tccgtcatga attgggttac ctattccaaa attttggttt
     1441 gattgaaaat caaacgattg aagaaaacct caaacttggt ctcattggtc aaaaattgaa
     1501 taaatctgag caaacgatga gacagaaaca ggccttagaa cgtgtaggtt tatcctatct
     1561 gaacctagat aaacgcattt ttgagctatc tgggggttag tcacaacgag ttgccttagc
     1621 aaagatcatc ttaaaaaatc cgccatttat tttggcagat gaaccaacgg cttcaataga
     1681 tccaaccacg tccaagttga ttatggagat tgtactgtct cttcgtgacg ctaacagatt
     1741 aatcatcgta gcaactcata atccagcaat atgggaaatg gctgatgaag tgatcactat
     1801 ggatagtttg cgataatgat tcataatttt tttggtattt ttagctatag agattatgtt
     1861 ttctcctaag ttaataggta aagcttgctt agaatacaat tttactcaca ttagtggaaa
     1921 gttggccaaa taacggtaaa atatgccgaa aagaagacta gaggggatca ttttggtctt
     1981 ctcttttttg gtctttataa cgattaatat cttcttttac aaaggataat ttagcagtaa
     2041 aataagggaa atcgtgctat aatagtttaa agtaatttat tctactacga ctattttgat
     2101 tttctttatc atataactgg taaaatggaa aatattacag tttcatatgt aaaagcaagg
     2161 tcaggagaca ggctgagcga gattacaggg taaaattgaa gaggcaatct attcagcaga
     2221 gaatagctat aagccagata ccattagaaa tcatttgata ttgttggcat taaaaataac
     2281 caaaacaagt tgcaattata tcgcttggtc tggagataat gcttaatatt tggtgatttt
     2341 ttggtgactc gcatgatttt taaaagacga ggggctaaaa acccttgata cgaaaggatt
     2401 ttacacacat ggctacgatt caatggtttc ctggacacat gtccaaggca aggagacagg
     2461 tacaggaaaa tattaagcat gttgattttg tgacgatttt agtagacgct aggctacctt
     2521 tatcaagtca aaatcctatg ctgaccaaaa ttgttggaga taagcccaag ctaatgcttc
     2581 ttaataaggc tgatctagca gataacacgc atactaagaa atggcaacaa tattatgaga
     2641 agcaagggat taagacatta gctatcaatg ctaaggaaca ggctacggtc aaaagggtca
     2701 ccgaggctgc taaggaattg atggcagata aactacgtcg cttaagagaa cgaggcattc
     2761 aaaaagaaac gctacgaacc atgattattg gcattccaaa tgctggcaaa tcaaccctga
     2821 tgaatcgctt ggcgggaaaa aaaattgcca cagtaggcaa taagccagga gtgaccaagg
     2881 gacagcaatg gctaaaatcc aataaagaac tagagatatt ggatactccg ggtatcttat
     2941 ggccaaagtt tgaagacgaa ttggttgggt taaaattagc cctgacaggg gctattaagg
     3001 atcagctgtt gccaatggac gaggtcacga tttttggatt gaattatttt aagaagtatt
     3061 atcctaatcg cctattaaag cgttttaagg ctattgatct agaggctgac gctccagaaa
     3121 tcatcatgtc cttgacacgt cagcttggct ttaaggaaga ctatgatcgt ttttacagct
     3181 tattcatcaa ggatattcgt gatggaagac ttggtcagta caccttagat caggttggtg
     3241 atgatgacag caatgactat taaagacatt aaagctcgtc tagaagctgt ttctagtctt
     3301 tctgatccat tttttgaaga gctaaaggcg gataagcggc ttggcgttca aaaggctgta
     3361 tctagcagaa aaagggcttt agaggctatc ttaaaagagg aagcccggct tgaggcgatg
     3421 ttgacgtatg aacaggcgct ttaccaaaaa ggctttcaag cgattgctgg tatagatgag
     3481 gttggtcgag gtcctctggc tggaccagtt gtagcagcct gtgttatact gccaaagggc
     3541 tgcaccatta aggggctaaa tgattctaaa aaaattccta aagctaagca tgaagcaatt
     3601 taccaagcca ttcaaaagaa agcgttggga atcggtcttg gaattattga caaccatacc
     3661 attgaccggg ttaatatcta tgaagcaaca aaattagcaa tgacagctgc cattaatcag
     3721 ctggagggct ctgtgagtaa gcctgattac ctgctcattg atgccatgac actagaggtt
     3781 tctattcctc aacaggctat tataaaaggc gatgcgagct ctatgtcaat cgctgcagcc
     3841 tctattgtgg ctaaggttac cagagatcga ttgatgcttg attacgataa ggcctttcca
     3901 ggctatggct ttgctaaaaa tgccggctat gggaccaagg agcacctgca gggattgcac
     3961 cagtatggtg tcacaccaat tcatcggcaa agctttgagc cgataaaatc aatgatctta
     4021 cgctaaaaat ctcattttga gaaaaggtag ctgccgaaag caaaaacgat agccactagg
     4081 tggatctaca attctggtat ttttcaatgg aatgctatgt gatgagctgc cctacaatgc
     4141 tcatacaaag gctaggaggc ctcgattttt ttgctggaat cctgtacagc tcctcaagag
     4201 tttgcaaaaa gctttgttta gt
//
LOCUS       DARYYD010000096         4069 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.097, whole genome shotgun sequence.
ACCESSION   DARYYD010000096 DARYYD010000000
VERSION     DARYYD010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4069
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.097"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            295..2097
                     /locus_tag="TV188_001892"
     CDS             295..2097
                     /locus_tag="TV188_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HEL1535207.1"
                     /translation="MEVRGAMGNRQMKLKKYFLRFLLLLFAAIYIYFSSFAYQHSYLG
                     ISADYVNHSWVVSNIHNGGEASSSGLAVGDKILEIDHKSSQDNPLLNKLLIVEQATSM
                     TVLHQGIQRQIVFQKTHGSKKIFLMFSLLSIILFALSYGYSRRHEISRTSQRYYIFTF
                     LTSLLLVSIIPSSMGNVVARLILVIYITLFPFFIDMFWRAGTLQQESVKFSKFSKLII
                     TYSAATLCLLLYSKWFSVPLVITIYLVRGIFYVSFTFLVALFLITLVKDIKNNAFPRL
                     NIVLLVILCLLPLFIGYVFPLPYDIPFMYTIPLLLLPILAIINNLIINRLTTFRFHLP
                     VPILYVFIAMLGTVMIICLYLISDFMPKWLMISYSFLLTLCSIPIVKDLIFLNIRTGY
                     QLSNKSIFLAVEAEREDISIYLHDTIIQDIIYYKKRLENMDAVSKKAASDILDDVIFE
                     LRELCSNIYPLMIQELGLKNAILDIISKFQKKESVIINDNIQVEQLDFGQPINNFILR
                     SIRELINNSILHGNAKEIDIHIYNAEQYVVIKIVDGGHFKTARQTEAPHFGLTVIAEK
                     LALLGGQLLVDKHPTTIVMLIPRKQVNYDKNSNH"
     gene            2075..2674
                     /locus_tag="TV188_001893"
     CDS             2075..2674
                     /locus_tag="TV188_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1535208.1"
                     /translation="MIKIAIIDDHELVLQGLYDRLKKETHFEVVGAFTSYQDLLFCLK
                     YKSVDVLIIDLMLKDIHGFDLIAQIQQKCQTVPKMILISGFYEPLLHKRALDLGIKAF
                     LPKECSYDELISTVYNVAKGNQVIPDDLLQREESHLLTESEIEILKLISDEYSNEKIS
                     KKLYISRRTVDTHVSNICAKLNVTSRVGAVREAIRLKLI"
     gene            2782..3708
                     /locus_tag="TV188_001894"
     CDS             2782..3708
                     /locus_tag="TV188_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="avirulence protein"
                     /protein_id="HEL1535209.1"
                     /translation="MVDVDTLLGDHKTRYFGDGHKRTSYSINHDQNNQAYGTITQSGV
                     WSNKSDKVIQPHLSTLDGIVLASLAAERYLKEQYEACEDFYLSQFSVKSGRKPIEDLN
                     RVPIVVQKSSFNGDKASFSVSVLDMTVNLVFKRIDTYTAKDNKPAAEAKDYLSNHLKD
                     IHHHIYDVNFLDALDIADKCSIFCKANKAIRHVSNYKGISSQLSSSYSLLELLIIFSQ
                     MAEMLAYYADDIDRRYSETLWMKNVSAELVEPIPDGELALLGKITKNKLLDMKGKDWK
                     LFEMSGTDTQNRVRISSKIAHQLPSSEMLNNA"
     gene            3701..>4069
                     /locus_tag="TV188_001895"
     CDS             3701..>4069
                     /locus_tag="TV188_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEL1535210.1"
                     /translation="MLNKEIRLVISGTYSTGKTTTATALSIATGIPLINALSAREILT
                     DLYPGRRFQDMNATELMALGLKRFEERVREEAILYLQHTNFISDGSVLNEWIYGTVRM
                     KVGLNPGSGFIHRAAKAILGL"
BASE COUNT         1256 a          754 c          786 g         1273 t
ORIGIN      
        1 gcctgtgccc taaccctctc acctagacgc aaaaagaatc aaaacaaccg ttaataggaa
       61 atcatgaaag ccttctatga cagtcattgt tcataggagg ttttttacac caaatagacc
      121 ttctattggc ttttcatttg attcttaatg gatttttact gctaatttct gactcaccat
      181 cgttgcattc gtctcattat ttacaaattt atttggctaa tattgaaaat atgttatgat
      241 taatgtatta ttttggtatt atttttaaaa aatattattt tagaatggta aaaaatggag
      301 gtgagaggag caatgggtaa ccgtcaaatg aagctgaaaa aatacttcct caggttttta
      361 ttgttattat ttgctgcaat ctacatttat ttttcctctt ttgcctatca gcattcctac
      421 cttgggataa gtgctgatta tgttaatcat agctgggttg tcagcaatat ccataatggc
      481 ggggaggcta gctcctcagg actagctgtt ggggataaga ttttagagat agaccataaa
      541 agcagccagg acaatccttt gttaaataag ctgttaattg ttgagcaagc aacctcaatg
      601 actgttttgc accaaggcat acaaagacag attgtatttc aaaaaacaca tgggtctaaa
      661 aagatatttt taatgtttag cctgttatcc attatcttat ttgccttatc ctatggctat
      721 tctagaaggc atgagatcag tcggaccagt cagaggtatt acatctttac ctttttaaca
      781 tcgttattac tggtttcgat tattccatca agcatgggaa atgttgttgc ccgcttgatt
      841 ttagtgattt acatcacttt gtttcccttt tttattgata tgttttggag agcaggtaca
      901 ttgcaacagg aatctgttaa attttcaaaa ttttcaaaac tgatcatcac ctattctgct
      961 gcaaccctct gcttattgct atattctaag tggttttcgg tcccactcgt cattaccatt
     1021 tatttggttc gaggaatttt ctatgttagc tttacctttt tagtggcttt atttttaatc
     1081 accttggtta aagatatcaa aaacaatgct tttccaagac tcaatattgt cctgttggtt
     1141 atcctgtgct tgctgccatt gtttatcggc tatgtgtttc ctttgcctta cgatatccct
     1201 tttatgtaca cgatacccct attgctgctg ccgattttgg cgatcattaa taacctaatc
     1261 attaacaggc tcacgacctt tcgctttcat ttgccagttc caatcctcta tgtgttcatt
     1321 gctatgctag gcactgtgat gatcatttgc ttgtatctca tatcagactt tatgcctaag
     1381 tggttaatga ttagttatag ctttttacta accctgtgct caataccaat cgtaaaagac
     1441 ctgatttttt taaatatcag aacaggctac cagctgagca acaagtctat tttcctagca
     1501 gttgaggctg aaagagagga tatttcgatc tacctgcatg atacgatcat acaagacatt
     1561 atttattaca aaaaaaggct ggaaaatatg gacgccgtct caaaaaaggc tgcttcagat
     1621 attcttgatg atgtaatctt tgaattaaga gagctgtgct caaatattta tcccttgatg
     1681 attcaagagc taggcttaaa gaatgctatt ttagacatta tctctaaatt tcaaaaaaaa
     1741 gaatcggtga ttatcaacga caatatccaa gtggaacagc ttgattttgg gcagcccatt
     1801 aataatttta tcctcagatc aatacgagag ctgattaata atagcattct tcatggtaat
     1861 gctaaggaaa tagatataca catctacaat gctgagcaat acgttgtgat caagattgtt
     1921 gatggcggac attttaagac tgctcgtcag acagaagcgc ctcactttgg cttaactgtt
     1981 atcgctgaaa agttagcatt gctgggtggt caattgcttg ttgacaaaca ccctacgact
     2041 attgtcatgc tcattcctag aaagcaggtg aattatgata aaaatagcaa tcattgacga
     2101 ccacgaattg gtcttacaag gcctatatga tcggttaaaa aaggaaacac attttgaggt
     2161 tgtcggcgct tttaccagct accaagattt gttattttgc ttgaaatata agtctgttga
     2221 cgttttgatt attgatctca tgctaaagga tattcatggc tttgacttaa ttgcacaaat
     2281 ccagcagaaa tgtcagaccg tgccaaaaat gattttaatt tcaggatttt atgagccctt
     2341 gctgcacaaa agagccttgg atctaggcat aaaggccttt cttccaaagg aatgctccta
     2401 cgacgaatta attagcactg tctacaatgt tgcaaaggga aatcaagtga ttccagatga
     2461 cttgctgcag agggaagaaa gtcatctgct aaccgagtca gaaattgaga tattgaaatt
     2521 aatctcagat gaatactcga acgaaaaaat ctccaaaaag ctctatatca gcagaaggac
     2581 tgttgatacc catgtttcaa atatatgtgc taagctcaat gtaacaagcc gagttggagc
     2641 ggtgcgggag gctatcaggc tgaagctgat ctaacaagtc aaccaaaaaa ggcagacaga
     2701 tattcgtaaa ttacggatgt ctgttttttg atagtgtttt atcataagcc ttggttataa
     2761 ataagaaaag gagagaaact aatggttgat gtcgatacat tacttggtga ccacaaaaca
     2821 aggtattttg gtgatggtca caaaagaaca agctacagta taaatcatga ccaaaataac
     2881 caagcttacg gaacaattac ccaatcgggt gtgtggtcaa ataaatctga taaggtgatt
     2941 cagccacacc taagcacctt agatggcatt gttctagcca gtctagcagc tgaaagatat
     3001 ctaaaagagc aatatgaagc atgtgaagat ttttatttat ctcagttttc ggtcaaatca
     3061 ggcaggaagc ctattgaaga tttaaacagg gttccaattg ttgtccaaaa aagctctttc
     3121 aatggggata aggcaagctt ttcggtgtca gtgctggata tgactgttaa tctagtattt
     3181 aaacgcattg acacctatac agcaaaagac aacaaaccag ctgcagaggc aaaggattac
     3241 ttgtcaaatc atctaaagga cattcaccat catatctacg atgttaactt tttagacgca
     3301 ttagatatag cagataagtg ctctattttt tgtaaggcta ataaggcaat ccgccacgtc
     3361 agcaattata agggcatatc ctctcagcta tcaagcagct attccttatt agagctcttg
     3421 attattttct cacagatggc tgaaatgttg gcatattatg ctgatgatat tgatagaaga
     3481 tacagtgaaa ccttgtggat gaaaaatgta tcagccgagc tcgttgaacc gatacctgat
     3541 ggtgagctgg cccttttagg taaaattacc aaaaacaaat tacttgatat gaagggcaag
     3601 gactggaagc tgtttgaaat gtcaggtact gacacacaaa atcgagtgag aatttcaagt
     3661 aaaatagccc atcaattacc tagttcggag atgcttaaca atgcttaata aagaaattag
     3721 acttgtcata tcaggcacct attctactgg taagacaaca acagcaacgg ctctgtctat
     3781 tgcgacaggc atacctttga ttaatgcact ttcagccaga gagatcctga ccgacctgta
     3841 tccaggcaga cgctttcagg acatgaatgc cactgagcta atggctctag gattaaaaag
     3901 atttgaggag cgggtgcgcg aggaagccat tttatacctc cagcatacca actttatctc
     3961 agatggctcc gtgctaaatg aatggatcta tggaacagta cgaatgaagg taggcttaaa
     4021 tccgggctct ggcttcattc atcgagctgc aaaggccatc cttggactt
//
LOCUS       DARYYD010000097         3909 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.098, whole genome shotgun sequence.
ACCESSION   DARYYD010000097 DARYYD010000000
VERSION     DARYYD010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3909
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.098"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..397
                     /locus_tag="TV188_001896"
     CDS             <1..397
                     /locus_tag="TV188_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1535211.1"
                     /translation="YVLTGGFLFTGFLLGLSFVLGAALIIYYKQYSEGYEDKKSYNIL
                     QEVGMSKQQVKKTINSQIVLVFFMPIAMAVLHFCVALVMLKQMLFLFGVLDTNLIYLV
                     SALTIAVIIVIYFTIYRITSKTYYNIIER"
     gene            441..1106
                     /locus_tag="TV188_001897"
     CDS             441..1106
                     /locus_tag="TV188_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEL1535212.1"
                     /translation="MIKAGKIYIVEDDAAILTPLKEHLSQNYQVLTVSNFRDIKQEVI
                     DYKPDIILMDITLPFFNGFYWTTEIRKTSTVPIVFISSSNDEMDTVMALNMGGDDFIS
                     KPFSLTILDAKIAAFLRRSQQFSSDDVTIDQFKLHFDGTLSNGTDSIHLSPTEHKILT
                     ILFTHPQQIVSKEDILARLWENESFIDQNTLNVNMTRLRKKISAIGFDCIHTVRGVGY
                     IIK"
     gene            1103..2080
                     /locus_tag="TV188_001898"
     CDS             1103..2080
                     /locus_tag="TV188_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEL1535213.1"
                     /translation="MIRAFFKEYYSWYIQYGVVMAGYLLIFWLYRLPLGYFKVTSLTI
                     LTLLILQGFGNYIRFKKKMKILQEFIYVKELDQLHSPSEQAYRSLIIKLKEAEAEVAL
                     YQLNNQKNTEALIKMWSHQMKLPLAAMSLMLQTNHIDIKDYQIQVLRLEHYLNNLLSY
                     LKFNQHSDDFRFQVCSVKQLVTSVIKKSSQTCIAKGISIAVDGDWQLSTDNKWLSFAL
                     TQIIDNAIKYSKPQGHIKVSIKEGSIFISDNGIGILEEDLPRLFEEGFTGYNGHEHQK
                     ATGLGLFMTKQILDKLNLNITISSQVDQGTLVVIQKKHSKQTKFSTSLL"
     gene            complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TV188_001899"
     CDS             complement(2180..3250)
                     /gene="xerS"
                     /locus_tag="TV188_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012658412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEL1535214.1"
                     /translation="MKRDLLLTKIEEYKNIMPWYVLDYYQSKLSVPYSFTTLYEYLKE
                     YKRFFEWLIDSDLSKAARIADVDLTTLEHLSKKDMEAFILYLRERPSLNIYSTKKGVS
                     QTTINRTLSALSSLYKYLTEEVENEHGEPYFYRNVMKKVATKKKRETLAARAENIKQK
                     LFLGDETMAFLDYVDKEYEYKLSNRAKASFRKNKERDLAIIALLLASGIRLSEAVNLD
                     LKDVNLNMMLVEVTRKGGKRDSVNVAAFAKPHLEAYLSVRKDRYQAEKQDVAFFLTAY
                     RGLPNRIDASSIEKMVGKYSEGFKIRVTPHKLRHTLATRLYDTTKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDKL"
     gene            complement(3407..3844)
                     /locus_tag="TV188_001900"
     CDS             complement(3407..3844)
                     /locus_tag="TV188_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEL1535215.1"
                     /translation="MLSKQKLSLEISHYLISGLLTTILYFVFRYVIYSWLHQATISAG
                     FANIIAIIAAFLMNDSYVFKQTSEKRLFRFAMFFLARVVTLGLDMLLAYLLVEKYPEV
                     IGSLVEHDSESINSVESILSQAIMISLNFIVSKYYIFKQHRSR"
BASE COUNT         1242 a          706 c          714 g         1247 t
ORIGIN      
        1 ctatgtccta accggtggct tcctttttac aggctttctt ttaggcttga gctttgtact
       61 tggggctgca ctgatcattt attacaagca atactctgaa ggctatgagg ataaaaaatc
      121 ttacaatatt cttcaagagg tcggcatgag caaacaacaa gtcaaaaaaa ccatcaattc
      181 ccaaattgta ttagtgttct ttatgcccat agctatggca gtcctacatt tttgtgtcgc
      241 tctggttatg cttaagcaaa tgctctttct ctttggcgtt ttagacacta atcttattta
      301 cctagttagt gcgctgacca ttgctgttat tatcgttatt tactttacta tttacaggat
      361 aacaagcaaa acctattaca atattattga aagataagac gagtggcgat ttttcgccac
      421 ttttttgata aaataatatt atgattaaag ctggaaaaat ttatattgtc gaagatgacg
      481 ctgctatctt aacaccctta aaagagcatc tgagtcagaa ctaccaggtt cttaccgtct
      541 ctaactttag agacattaag caagaggtga ttgattataa accggatatc atccttatgg
      601 acatcacctt accgtttttt aacggctttt actggacaac agaaattcgt aaaacgtcaa
      661 cagtgccaat tgtttttatc tcaagcagta atgatgagat ggatacggtc atggcactta
      721 atatgggggg agatgatttc atctctaaac ccttttctct aaccatttta gacgcaaaaa
      781 tcgcagcctt tttaagacgc tcacagcaat ttagcagtga tgatgtgacc atagatcaat
      841 ttaagctaca ttttgatggc accttatcta atggcacaga tagcattcat ttatcgccaa
      901 cagagcacaa aatcttaacg attttattta ctcacccgca gcaaattgtt tcaaaggagg
      961 atattctagc aaggctttgg gaaaacgaga gctttattga tcaaaacacg cttaatgtta
     1021 acatgacgcg tctacgcaaa aaaatatcag ctattggttt tgactgtatt cacacagtga
     1081 gaggagtagg ctatattatc aaatgataag agcatttttt aaggaatatt attcctggta
     1141 tatccagtat ggggttgtta tggctggtta tctgctgatc ttttggcttt ataggcttcc
     1201 tttaggctat tttaaagtga ctagcctaac catactaacc ttgctaatat tgcaaggttt
     1261 tggaaactat attaggttca aaaagaagat gaagatttta caagaattta tttatgtaaa
     1321 agaactagat cagctgcact cccctagcga acaagcctat aggtctttga ttattaagct
     1381 taaggaagca gaagcagagg tagcactgta ccaacttaac aaccaaaaga atacagaagc
     1441 actgattaaa atgtggtctc accaaatgaa gcttccccta gcggctatgt ccttaatgct
     1501 tcaaaccaat catattgata ttaaggatta tcagattcag gttctacgct tggagcatta
     1561 cctcaacaat ctattaagct atttgaagtt taaccagcat agtgatgatt ttcggtttca
     1621 ggtttgctct gtaaagcagc ttgtgacctc agttatcaaa aagtccagcc agacttgtat
     1681 cgctaagggg attagcattg cagttgatgg cgattggcaa ttgagcactg acaacaaatg
     1741 gctgtcattt gctctgacac aaatcattga caatgcaatc aaatattcta agccacaagg
     1801 ccacatcaaa gtcagcatta aggaaggcag tatttttata tcagataatg gtattggaat
     1861 actagaggaa gatttgccac gtctgtttga agaaggcttt actggctaca atggccatga
     1921 gcatcaaaag gcaactggtt taggcctctt tatgacaaag caaatccttg ataaattaaa
     1981 tttaaacata actatttcca gtcaagttga ccaaggaact ttagttgtaa ttcaaaaaaa
     2041 gcattctaaa cagaccaaat tctcgacttc tttgctgtaa aaaataacag ctataaatcc
     2101 ctataatagt gacaaagagg attaaaacat tgcaaaaaaa gactgaaagt acagattaca
     2161 taattttagt tatgtaaatt tataatttat ctagggcatt tttttgctca tcgttaacaa
     2221 tatgagtata gaggtctgta acttgggtcg aggcatgacc aagctgatga cttactagga
     2281 cctgtgactt tgtagtatca taaagtctcg ttgcaagcgt atggcgtagc ttatgaggag
     2341 ttacacgaat tttaaagcct tcagaatatt tacctaccat tttttcaatg cttgaggcat
     2401 ctatccgatt ggggagccca cgataggctg ttaaaaagaa ggctacatcc tgtttttctg
     2461 cttgatagcg gtcttttcga actgataaat aggcttctaa atgaggcttg gcaaaagcag
     2521 caacattgac cgaatctctc ttacctccct tacgggtaac ctcaaccagc atcatgttga
     2581 ggttgacatc cttaaggtct aggttaactg cctcggataa ccgaatacca gatgccagca
     2641 gtagggcgat aatggctagg tcgcgttctt tattttttcg gaaagaagcc tttgcccgat
     2701 ttgacagctt atattcatat tctttatcca catagtctaa aaatgccatc gtctcatcgc
     2761 ctaaaaaaag cttttgttta atattttcag ccctggctgc taaggtttct cttttctttt
     2821 tggttgccac ctttttcatg acatttcgat aaaaataagg ctctccatgc tcattttcaa
     2881 cctcctcagt aaggtattta tacaagctgg atagtgcaga aagggtacga ttaatggtgg
     2941 tttgcgatac ccccttttta gttgaataga tgttcaagga aggacgctca cgaagataga
     3001 gaataaaggc ttccatatcc tttttactca aatgctccag agtagtcaag tccacatcag
     3061 caatcctagc agcttttgat agatcagaat caattaacca ctcaaaaaag cgtttgtatt
     3121 ctttcaggta ttcgtacaag gtcgtaaagc tataaggaac agatagctta gattgataat
     3181 aatcaaggac ataccaaggc atgatgtttt tgtattcttc aattttagta agtagtaaat
     3241 cacgtttcat aataaattct cacaatgttt cgtcaacaaa tgaattatcc attggatatc
     3301 agactgatag tagtatatca catcttgggg tatttttcaa gaaaattata gtttttcgga
     3361 aagatataaa attatttaat agttattttg ctaagctaag gctgttttat ctgctacgat
     3421 gctgcttaaa aatatagtat ttactaacaa taaaattcaa gctaatcatt atggcttggc
     3481 tcaaaatgct ttcaacagaa ttaatgcttt cagaatcatg ttcaacaagg cttccaatga
     3541 cctctgggta tttttcgact aataaatagg ctaatagcat atctaagcct aatgttacta
     3601 ctctagctag gaaaaacatg gcaaatctaa acaagcgttt ttcagaagtt tgcttaaaaa
     3661 catagctatc gttcatcaag aaggcagcta tgatcgctat aatattggca aagcctgctg
     3721 atatggtggc ctgatgtaac catgaataga tgacataccg aaaaacaaaa taaagaatgg
     3781 ttgttagaag accagatatc aggtaatgac tgatttcaag tgataatttt tgtttgctaa
     3841 gcatttttct ttcctatgtg tatttatctt gactgttata ttttgatgga tctatataag
     3901 tataacatg
//
LOCUS       DARYYD010000098         3711 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.099, whole genome shotgun sequence.
ACCESSION   DARYYD010000098 DARYYD010000000
VERSION     DARYYD010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3711
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.099"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..405
                     /locus_tag="TV188_001901"
     CDS             <1..405
                     /locus_tag="TV188_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEL1535216.1"
                     /translation="GRGFYKKYMNAYGQVARLHSQQWYTDVVHLPVEFPMSADGHRPV
                     SERYRTLSDKEIREGFLSIGKTPELVSGSQVERLRKIINLYDLPVVVPIDEAVTQAEE
                     QIRTNREAVSKRIIEQYKEPSLKEKIKFISEF"
     gene            414..1085
                     /locus_tag="TV188_001902"
     CDS             414..1085
                     /locus_tag="TV188_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1535217.1"
                     /translation="MISFKNISKTYQVGDQEVKVLDDVSFTIEKGRFTVILGPSGSGK
                     STLLNLLGGMDRASKGTFIFEGKDITALNDKALSDYRKEVVGFVFQFYNLIPSLTALE
                     NISIAAQLTGNTAQSEVLLDKVGLSHRKNNFPSQLSGGEMQRVSIARALAKKPKLLLC
                     DEPTGALDSKTGQHIMQLLQEASKDEDVAVVLVTHNTEFKAFGDTIIYLKDGKISSID
                     HKQSV"
     gene            1102..3375
                     /locus_tag="TV188_001903"
     CDS             1102..3375
                     /locus_tag="TV188_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1535218.1"
                     /translation="MKYLNLKLRRDLKHHWQQFFSVFLMSLLSVLIFVGLQGAWHGLE
                     KSLDNYISTSHLPTVWVQATNLTKQDIEKIEALNQVSKVRPKIRVTAAIDSDSDLEHY
                     LTLDSLQSTSDQVTRVVAGEAFSTKETDKVWLNKEYADANHLSLGDKISLTLSGQSIS
                     VTLAGLVQSADRIYFTGSLEYIAPNYDNYAYGYISKKSLAKLLQTQLPDNMVDIYASS
                     DDLRDDIENILGNKLVSYYNQTTLTDVSEAVDRVGQIRNLSYLFSFIFILLAILSMFT
                     TIRRLIESQTKEIAIIKALGYSNIQVSGHYISFGLLVGTLGALSGLLVSPAMSWFVLE
                     TQKRMFSLPKWEIAYSLSSLVVALLVVMICVTSAYFASRKAIKGLPAVFLRGKNRDVK
                     HILLEKIKPLWRSISDEAKWAIRDALTHRIRILMGIIGVAGSMMLLIAGIGMPISMNH
                     LVDKAYNKDFSYSKRLTVSDYESANKAYKGQWVQINQAHFSKDDGYNRLLIIISKGSL
                     VNATTEDGDKIKEGGLYVTNSFAKLANIKVGDKLSVTPYQDKHQYTFSVKGILTSETN
                     QGAYIMADTFKKAGGAFHPHTLLVDKQVSASTIAQDQNVLTVIDKSSQESNAYDLVNS
                     LMSVFLMIIGFALLLVIVVLYNLGSLNFVERTRDYATLQVLGFSKRNLQNITMLENLM
                     TTSVGWLLGIPMGIWFLEQYVATFSTIRLEYTAYVTWQVLLAASVLVWLTSLMTTLFI
                     SRKIRTIDMVDALKGVD"
BASE COUNT         1108 a          762 c          776 g         1065 t
ORIGIN      
        1 ggaagaggct tttataaaaa atacatgaat gcctatgggc aggtggcaag gctgcattct
       61 cagcaatggt acaccgatgt cgttcatctt cctgttgaat ttcctatgtc agccgatggg
      121 cataggccag tctctgagag gtaccggaca ctatcagaca aagaaatcag agaaggcttt
      181 ctctccattg gaaaaacacc ggagcttgtc agtggcagtc aggtcgagag attgcgaaaa
      241 atcattaacc tatatgacct gccggttgtc gttccaattg acgaggcagt cactcaagca
      301 gaggagcaaa tcagaaccaa cagagaagct gtctccaagc ggattattga gcagtataaa
      361 gagccttcat taaaagaaaa aataaaattt atatcagaat tttaggagtg tagatgattt
      421 catttaagaa tattagcaag acataccaag tcggagacca agaggttaaa gtattagacg
      481 atgtttcctt tacgattgaa aagggaaggt ttactgttat tttaggcccc tctggttcag
      541 gaaagagcac gctcttaaat ttacttggag gaatggaccg ggcaagcaag ggaaccttta
      601 tctttgaggg taaggacatt acagccttaa atgataaagc attatctgat tatcgcaaag
      661 aggttgtagg ctttgtcttt cagttttaca atcttattcc aagcctaaca gccttagaaa
      721 atatcagtat cgccgcacag ctaaccggaa acacagcaca atcagaggta ttgttggata
      781 aggtggggtt atctcatcgg aaaaacaatt tccctagcca gctgtcaggc ggagaaatgc
      841 agcgcgtatc catagccaga gctctggcaa agaagccaaa attattgcta tgtgatgagc
      901 ctaccggtgc ccttgattcc aaaacagggc agcacattat gcagctactt caggaagcgt
      961 caaaggacga ggacgtagcg gttgtcttgg tgacacataa cactgaattt aaagcttttg
     1021 gcgataccat tatttaccta aaggacggaa agataagctc gattgatcat aaacaatcag
     1081 tttagaggat tggagctaaa catgaaatat cttaatttaa agctaaggcg agatttaaag
     1141 catcattggc agcaattctt ttcagtgttc ttgatgtcct tattaagtgt tttaatcttt
     1201 gttggtctac agggtgcttg gcatgggctg gaaaaaagct tagacaacta tatatctacc
     1261 tctcatttgc caaccgtttg ggtacaggct actaatctaa caaaacagga cattgaaaaa
     1321 atagaggcct taaatcaagt cagcaaggtt agacctaaga ttagggtcac tgctgctatt
     1381 gattctgaca gcgacctaga gcattactta acgctagatt cattacagtc tacctcagat
     1441 caggtgacac gtgttgtagc tggcgaggcc ttttcaacca aagaaaccga taaagtatgg
     1501 ttgaacaagg aatatgctga cgctaaccac ctatccctcg gtgataagat cagcttaaca
     1561 ctatcaggtc aatcaattag tgtgactctt gcgggtcttg tccagtcagc agacaggatc
     1621 tactttacag gcagcttaga gtatatagct cctaattatg ataactatgc ctacggctac
     1681 atctcaaaaa agagcttagc taagctcctt cagacgcagc tgcctgataa tatggttgac
     1741 atttacgcct cgtctgacga tcttcgagac gacatagaga acattttagg caataagctt
     1801 gtttcttatt acaatcaaac aaccctaact gacgtctctg aggcagttga tagagtagga
     1861 cagattagga atctctctta tttgttctcc tttatcttca tcttactagc tattctatcc
     1921 atgtttacca cgatcagacg tctcatcgaa agtcaaacaa aggaaattgc tatcatcaag
     1981 gccttaggct attctaacat acaggtcagt ggccactaca tttcctttgg cttgttggtt
     2041 ggaacattag gtgctctttc tggtcttctg gtatctcctg ctatgtcctg gtttgtccta
     2101 gagacccaaa agagaatgtt ctcacttcct aagtgggaaa ttgcttactc tctgtcttcc
     2161 ctagtagttg cattactggt ggttatgatt tgtgtgacat ctgcttactt tgcttctcga
     2221 aaagccatta aagggctgcc agcagtattc ttacgaggaa aaaacaggga cgtcaagcat
     2281 attttgctcg aaaaaatcaa gcccttatgg cgtagtattt ctgacgaagc taagtgggct
     2341 atacgtgatg ctttgacaca ccgcatcaga attttaatgg ggattatagg ggtagctggt
     2401 agtatgatgc ttttaattgc cggtattggc atgcctatct ctatgaatca ccttgttgat
     2461 aaggcctata acaaggactt tagctactcc aaacgcttga cggtttctga ctacgaatcg
     2521 gccaataagg cctataaagg ccaatgggtg caaatcaatc aagcccactt ctcaaaagat
     2581 gacggctaca atcgtctctt gattattatc agcaagggaa gccttgttaa cgccaccaca
     2641 gaagatggtg acaagataaa agagggtggt ctctatgtta ccaacagctt tgccaagcta
     2701 gccaatatca aggttggaga caagctatct gtcacaccct accaggataa gcatcagtat
     2761 acctttagtg ttaagggaat tctgaccagc gaaactaatc aaggtgccta tatcatggct
     2821 gataccttca aaaaagcagg cggagctttt cacccacaca cattgttagt agataagcaa
     2881 gtttctgctt ctacaatcgc tcaggatcag aatgttttaa ccgtcattga taagtccagc
     2941 caagaaagca atgcctatga ccttgtcaat agtctaatga gtgtcttttt gatgatcatt
     3001 ggctttgcct tgctgctagt catcgttgtg ctgtataatt taggctcttt aaattttgta
     3061 gagcgcacaa gagactacgc aacccttcag gttctaggat tttcaaaaag aaatctccaa
     3121 aacataacaa tgctcgaaaa tctcatgaca acctctgtgg gctggctctt gggaattcct
     3181 atggggattt ggtttttaga gcagtatgtc gccaccttct ctacgatacg tcttgaatat
     3241 acggcttatg tcacttggca ggttctgcta gcggcaagtg tccttgtctg gctaacatca
     3301 ttaatgacca ctcttttcat cagtagaaag attagaacaa ttgacatggt tgatgcctta
     3361 aagggagtcg actaacctca ctttatcaca tacctgactc tctctctttt atggttaagc
     3421 atcatcactg cactggttct gatatgatga ctgataaagc tgtaattgtg ctgtaacaag
     3481 cactgtcatt acatagcaac acccttaaaa acaagcatca gatttggtgc ttgtttttga
     3541 atttattgct aatgctaaac gcaacgatta tcacaaatca tgcagtacac gcttataaca
     3601 gcttaagcat gcccattatt caaaaaacgt tgatcaaaat gacttccctg aagtttagat
     3661 cattcctcaa tttattgata caaatgtgat aaagtcatac gatcttcttg t
//
LOCUS       DARYYD010000099         3507 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.100, whole genome shotgun sequence.
ACCESSION   DARYYD010000099 DARYYD010000000
VERSION     DARYYD010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3507
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.100"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(88..291)
                     /locus_tag="TV188_001904"
     CDS             complement(88..291)
                     /locus_tag="TV188_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class IIb bacteriocin, lactobin A/cerein 7B
                     family"
                     /protein_id="HEL1535219.1"
                     /translation="MKQYEDFQMLYELDLASVNGGKINWGSVAGHCAGGAIVTGAFSG
                     PLYVLGAGIGCIVGAGQAIINGL"
     gene            complement(308..565)
                     /locus_tag="TV188_001905"
     CDS             complement(308..565)
                     /locus_tag="TV188_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEL1535220.1"
                     /translation="MNTETINQFDVMNIEALATVEGGYSGKDCLKDMGGYMLIGAGSG
                     ALWGAPAGGIGVLPGAFVGAHVGAIGGGFACMGGMIGNRFN"
     gene            complement(886..2253)
                     /gene="rlmD"
                     /locus_tag="TV188_001906"
     CDS             complement(886..2253)
                     /gene="rlmD"
                     /locus_tag="TV188_001906"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEL1535221.1"
                     /translation="MNVKIKQKIPLKIKRMGINGEGIGFYKKTLVFVPGALKGEEVFC
                     QVTAVKRNFAEARLLVINKASKNRVKPACSIYETCGGCQIMHLAYPKQLYFKDDIIRQ
                     ALKKFKPKGYEEFEIRHTLGMAEPQHYRAKLQFQTRSFGGSVKAGLFSEGSHCLVAID
                     DCLVQDQLTQAIVNHVTQLLDRYRIPIYNERRVAGIRTVMVRRAQASDQVQLIFVSSK
                     EVRLAGLIAELTAAFPQIRTVALNINTSKTSDIYGAKTEILWGQETIQEEVLSHSFAL
                     SPRAFYQLNPTQTEVLYSQVVQALEPTAEEHIIDAYCGVGSIGLAVANKVRSVRGMDI
                     IPEAIADARKNAQALGFDNAYYETGKAEELIPSWYAEGYRADALIVDPPRTGLDDKLL
                     QTILHYQPAKMVYVSCNTSTLARDLVPLVQVYDVIYIQSVDMFPHTARTEAVVKLQKR
                     QKPQQ"
     gene            complement(2250..3218)
                     /locus_tag="TV188_001907"
     CDS             complement(2250..3218)
                     /locus_tag="TV188_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEL1535222.1"
                     /translation="MTEKDKKDRDKVVSLQHYRQADAEDDMLFGHETEFFSDDLEALL
                     NSMDNQLLSDLEHFAGDRAYDLIKYLAFDEDCQHQAWLASKPMGWVNLEERPYLSQKF
                     ELAMLYKQNGLYEKALHHLLEIHQYDEGDHLGTRYEILALYVLKSDFTMAEAFYDSKD
                     YHRGDLLMEVPLMVGALLAEREELADDILANLAETVPDFVAIVRQKAFPIDDILAAGA
                     LESYEPNSLSSIYLAFFNILPLLMTAQYYLQHYVQEFFEGAEGELTFLEELDLPLSKV
                     NLFNQYGIHTLEDFSAWTTQELLDIPGVGKQMIARLKRLGVIFSQE"
     gene            complement(3358..>3507)
                     /locus_tag="TV188_001908"
     CDS             complement(3358..>3507)
                     /locus_tag="TV188_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1535223.1"
                     /translation="DCDYITGDTVMIVRKNGRIFDYVLPNEEIRDWEVVIEERVEEVM
                     RELDK"
BASE COUNT         1024 a          881 c          557 g         1045 t
ORIGIN      
        1 attcttatca acgcttcttc ttttttaaca acaccaaata tcaatagtat aatcggaact
       61 aaaactaata ctactaataa tattgtttta taatccattg ataatggcct gtcctgcacc
      121 aacaatgcat cctattcctg cacccaatac atacaatgga ccagagaaag cacctgtaac
      181 gattgctcca cctgcacaat gccctgcaac agagccccaa ttaattttac cgccatttac
      241 acttgccaaa tcaagctcat ataacatctg aaaatcttcg tactgcttca tggtatatac
      301 tcctttctta gttaaatcta ttacctatca ttccacccat gcatgcaaaa cctcccccaa
      361 ttgcaccaac atgtgcacca acaaatgcac ctggaagtac gccaatccct cctgctgggg
      421 caccccacaa agccccactt ccagctccta ttaacatata tcctcccatg tctttaagac
      481 agtccttacc agaatatcca ccttcaacag ttgcaagagc ctctatattc ataacatcaa
      541 attgattaat cgtttctgta ttcattttga atacctccat aacatatttt ttctttatgt
      601 cgcgatcacg atttaagtat agcattctag tatcatattt tttctaaaag tcttaaacgg
      661 tcgttttttc atcgtaaacg gtcattttca atcgttttca accgttcaag acaaaattaa
      721 ctaccattca ggattttcat tggataaata gctatttttt ggctctttgc caacccacta
      781 aagctattaa taaaaaaata agacagtagt cacatttagg ctactgtctc ttttatctaa
      841 agccttgatc ggtaagaaaa gagccagtct tttccaacta atcgattatt gttgtggttt
      901 ttgtcgcttt tgtagcttca ctacagcctc ggtccttgct gtgtgtggaa acatgtcaac
      961 agattgaata tatatcacat catagacctg aaccaagggt accagatcac gagccaaggt
     1021 tgaggtatta caggagacat aaaccatttt agctggctga tagtgtaaaa tcgtttgtaa
     1081 tagcttgtca tctagtcctg ttcgaggtgg atctacaatc aaggcatcag ctcggtagcc
     1141 ttcagcgtac cagcttggga tcagttcctc tgccttgcca gtctcataat aagcattgtc
     1201 aaagcccaat gcctgcgcat ttttcctagc atcagcaatt gcctctggaa taatatccat
     1261 accacgaaca gatcttactt tgtttgcaac tgccagacca attgagccaa caccgcaata
     1321 agcatcaata atatgctcct cagctgtggg ctcaagcgcc tgaaccactt gactatataa
     1381 aacctctgtc tgtgtgggat taagctgata aaaggctctt ggcgacaggg caaagctatg
     1441 gctcaaaacc tcctcttgaa tggtctcctg accccagaga atctcagttt tggcgccata
     1501 aatatcactc gtttttgaag tattgatgtt taaagcaaca gtcctgattt gtggaaatgc
     1561 agcagtcagc tcagcaataa gacctgccag cctcacctct ttactgctta caaaaatcaa
     1621 ctgaacctga tcactggcct gtgccctacg aaccataact gtacgaattc cagctactct
     1681 gcgttcatta tagataggaa tcctataccg atcaagcagc tgagtcacat gattaacaat
     1741 cgcctgtgtt agctgatcct gaaccagaca atcatcaatg gcaaccaagc aatggctccc
     1801 ttctgaaaat aagcctgcct tgacggagcc accaaacgaa cgcgtctgaa actgtaattt
     1861 tgctcggtaa tgctgcggct ctgccattcc taaggtatga cgaatctcaa actcttcata
     1921 ccccttaggc ttaaactttt ttaaggcctg ccgaatgatg tcatccttaa agtagagctg
     1981 cttaggatag gccagatgca tgatttgaca gcctccacag gtctcataaa tggaacaggc
     2041 cggcttcacc cggtttttag aagccttatt aatcaccaag agccttgcct cagcaaaatt
     2101 gcgcttaaca gcagtcactt gacaaaaaac ctcttctccc ttcaaggctc cgggaacaaa
     2161 gaccaaggtc tttttataaa aaccaattcc ctcaccatta atccccattc gcttaatctt
     2221 aagcggtatt ttttgcttta ttttgacatt cattcctgac taaatattac tcctaatcgc
     2281 ttaagccttg ctatcatctg cttgccaaca cctggaatat caagaagctc ttgagttgtc
     2341 caggccgaaa aatcctccag agtatgaatc ccatactgat taaacaaatt gaccttactt
     2401 aaaggaagat caagctcctc tagaaatgtt agctcgcctt cagccccttc aaaaaattcc
     2461 tgaacataat gctgcaggta atattgtgca gtcatcaata gcggtaggat attaaaaaag
     2521 gcaaggtaaa tacttgataa gctgtttggc tcgtagctct ccagggcacc agcagctaaa
     2581 atatcatcta tcggaaaggc tttctgtctg acaattgcca caaagtctgg caccgtctca
     2641 gcaaggttag ccaaaatatc atcagctagc tcttctcttt cagctaatag cgctccaacc
     2701 atcaaaggaa cctccatcaa cagatctcct ctatgataat ccttactgtc ataaaaagcc
     2761 tctgccatcg taaaatcaga ctttaacaca taaagagcta agatttcata ccttgtccct
     2821 aagtgatccc cttcatcgta ttgatgaatt tctaagaggt gatgtaaagc tttttcataa
     2881 agaccatttt gcttatacag catcgccagc tcaaattttt gagacaagta aggtctctct
     2941 tcaagattca cccatcccat aggcttagaa gcaagccagg cctgatgctg acagtcttca
     3001 tcaaaggcca aatacttgat taagtcatag gctctatctc ctgcaaagtg ctccaagtcc
     3061 gacaacaact ggttatccat gctgtttaaa agagcctcta agtcatcact gaaaaactct
     3121 gtctcatgtc caaagagcat atcatcttct gcatcagctt ggcgatagtg ctgtaagcta
     3181 acaaccttat ctctatcttt tttatctttt tctgtcataa tgccctttca atctattgac
     3241 catttatact cttattttac catttttgtt ataatgaggg tatagataaa actcctaaaa
     3301 ttgtggcttt acaatgtcgt tccccgacaa ttccccgact tctggacgag gtctttttta
     3361 tttgtctaat tctctcatca cctcttccac tctttcctct atcacaacct cccaatctct
     3421 tatctcctca ttcggcaaca cataatcaaa aatccgtccg tttttgcgca caatcataac
     3481 tgtgtctcct gtgatatagt cacagtc
//
LOCUS       DARYYD010000100         3213 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.101, whole genome shotgun sequence.
ACCESSION   DARYYD010000100 DARYYD010000000
VERSION     DARYYD010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3213
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.101"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            204..923
                     /locus_tag="TV188_001909"
     CDS             204..923
                     /locus_tag="TV188_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1535224.1"
                     /translation="MPRFSKAFQYMGATTMLGLSLLAANVNANTNADTVTVDLTYTAY
                     SNLTNEQKAGIQKGTPNEVPIQDKLHYVLVYDKSCGVTASPKGMMSTPKANAKVLPKT
                     GGAADGLVGLAVGLGLLSVSGYLIYKNRKSGSYVLIALLVAGGATTAVSAVDVVRHLN
                     DIVTKTTVKGVSFTYTPEEKVDDYCYVGYIVTQENSPAPTPEPKPDPVPTPEPKPEPK
                     LDPVPTPEPTPDPEYFEAIPQ"
     gene            complement(1035..>3213)
                     /locus_tag="TV188_001910"
     CDS             complement(1035..>3213)
                     /locus_tag="TV188_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HEL1535225.1"
                     /translation="FKTFITSFINTRLGFVLTLLFCFWIKTLWAYHADFSLDLGNAYQ
                     VFLTIINPIPLALLLLGFTLYIKNTRAFYISSWIVYIILNLLLISNSIYYREFSDFIT
                     VSAMLASSKVSAGLGDSALNLLRIWDIVYVLDFIILISLSVTKTIKKDPRPFNKRASF
                     AVTALSCLLLSVNLFLAEIDRPELLTRGFSNTYIVRALGLPAFTIYSGNQTYQAQKER
                     NGATAEELVDVKQYVKNHYAAPDPQYFGIGKGKNVIVIHLESFQQFLIDYKLKDDDKD
                     YEVTPFINSLYHSNATLAFSNFFHQVKAGKTSDAETMMENSLFGLNSGSFMVNYGGEN
                     TQFATPSILAQNGGYTSAVFHGNVGTFWNRNNAYKQWGYHYFFDSSYFSKQTDKNSFQ
                     YGLNDKYMFRDSIKYLEQLQQPFYTKFITVSNHYPYTSLRGESSEEGFPLAKTDDETI
                     NGYFATANYLDSALKSFFDYLKATGLYDNSIFVLYGDHYGISNSRNVSLAELLGKDPE
                     TWSEYDNAMLQRVPYMIHIPGYTNGGIKETFGGEIDSLPTLLHILGIDTSKMVQLGQD
                     LLSPQNSQMVAQRTSGTYITPDYTSYSGRLYNTQTGLEITNPDEMTMAKVKEIRAAVA
                     QQLAASDAIQTGDLLRFDTDNGLKPVDPTTFIYTKQLKQLKEISEKLGSHSTSIYSKN
                     GNKSTQKLFKAPSYLELNPKEAEKPESTSSSDPKEESVKEQSQ"
BASE COUNT          955 a          581 c          706 g          971 t
ORIGIN      
        1 gtgtcaataa ggtgatttat tgttatgata tgcttaaagc tgctgagatt tggtcaatat
       61 ctattgatat gagtgtattt gaaattttta gatagtgctt acaaaaatca catttaccta
      121 taataatcat aagattgata tgataggaga tgccttttta gttattggtt ttattctaca
      181 aaacattaag gagaatagtt ataatgccac gtttttctaa agcgtttcaa tacatgggag
      241 ctacaacgat gttaggtcta tctttgctag cagctaatgt caatgccaac actaatgctg
      301 atacggtaac ggtagatttg acctatacag cctattctaa tctgacaaat gaacaaaaag
      361 caggcattca aaaaggcact ccaaatgaag tacctatcca agataaattg cattacgttc
      421 ttgtttacga caaaagctgt ggagtgacag catctccaaa aggaatgatg tctaccccta
      481 aggctaacgc taaggtcttg cctaaaacgg gtggtgcagc agatggtctg gttggtttgg
      541 cagtagggct aggcttacta agtgtttcag gctatcttat ttacaaaaat aggaaaagcg
      601 gtagctatgt gttgattgcc ttgttggtag ctggtggtgc gacaacagct gttagtgcag
      661 ttgatgtggt acgtcatctc aatgatatcg tcactaagac tacggttaag ggggtaagct
      721 ttacttacac tccagaagaa aaggttgatg attactgtta tgtgggttat attgtgacgc
      781 aagaaaatag cccagcaccg acacccgaac ctaagccaga tcctgtgcca acaccagaac
      841 cgaagcctga gcctaagcta gatcctgtgc caacacctga accgacacca gatccagaat
      901 actttgaggc cattcctcaa taaaagtgtc agaactaaaa agccctcatt aagttgtaac
      961 gctcaatgaa ggcttttagc ttgcttttag tcttctacga gagcgatcct agtgaggctt
     1021 gctttagaca tccactactg actttgttcc ttaacggatt cttctttagg gtcagaagac
     1081 gaagtagatt caggtttttc ggcttcttta ggatttaact ccagataaga aggtgcttta
     1141 aagagctttt gagttgattt gttgccattt ttactataaa tgctggttga atgtgatcct
     1201 aatttctctg atatctcttt gagttgtttt agctgcttgg tataaatgaa ggttgttggg
     1261 tcaacaggtt tcagaccatt atcggtatca aagcgtagta ggtctcctgt ttggatagcg
     1321 tcactagctg ctagctgctg agcaacggct gctcgtattt ctttgacctt agccattgtc
     1381 atctcatcag ggtttgtaat ttccaagcct gtttgagtgt tgtaaaggcg accgctatag
     1441 ctagtgtagt ctggcgtgat ataagttcca gaggttcttt gtgctaccat ttgactattt
     1501 tgtggcgaca agagatcctg tcctagttga accatcttgc tggtatcaat gcccaagata
     1561 tgcagtaagg ttggtaagga atcaatttct ccgccaaagg tttctttgat cccgccattg
     1621 gtatagcctg gaatatggat catatatggt acacgctgga gcattgcatt gtcatattcg
     1681 gaccaagttt cagggtcttt acctagtaat tctgccaagc tgacatttct ggaattagaa
     1741 ataccatagt ggtcaccata tagaacaaag atagaattgt cataaagtcc tgtcgccttg
     1801 agataatcaa aaaatgattt caaggctgaa tccagatagt tagctgtagc aaagtaacca
     1861 ttgatggttt catcatcggt tttggctagt ggaaagccct cttcactgct ttcgcctcta
     1921 aggctggtgt aagggtagtg gttgctgacg gtaataaact tagtgtagaa gggttgttga
     1981 agctgttcaa ggtacttgat agaatctcta aacatgtatt tgtcatttag gccatactgg
     2041 aaagagtttt tatcagtctg ttttgaaaaa tagcttgaat caaaaaagta atgatagccc
     2101 cattgcttat aagcattatt gcgattccag aaggttccta cattcccatg aaagacggca
     2161 ctagtatagc cgccattttg tgctaggatt gatggtgtgg cgaattgtgt gttttcgccg
     2221 ccataattta ccataaaaga accactgttt aagccaaata atgaattttc catcatggtc
     2281 tctgcatcag acgtttttcc agccttgacc tgatggaaaa agttagagaa ggctagtgtg
     2341 gcattggagt ggtagaggga attaataaaa ggtgtgacct catagtcctt gtcgtcatcc
     2401 ttgagcttgt aatcaataag aaattgttgg aagctttcca agtggatcac aatgacattt
     2461 tttcccttac cgattccaaa atattgagga tcaggtgcgg cgtagtggtt cttgacatat
     2521 tgcttaacat cgactaattc ttcagcggtt gctccgttac gctctttttg tgcttgatag
     2581 gtctggtttc cgctgtaaat ggtaaaagca ggcaatccaa gcgctctaac gatataggta
     2641 tttgaaaatc ctctagtcag aagctccggg cggtcaatct ctgcaagaaa cagattaaca
     2701 gataagagca agcaagacag tgctgtaaca gcaaaggaag cccgcttgtt aaaaggacgc
     2761 gggtcttttt tgatggtctt agttactgat aaactaatca gaatgatgaa atcaaggacg
     2821 taaacaatat cccaaatgcg caaaaggttt aaagcagagt ctcctaaacc agcagaaacc
     2881 ttactactgg ctagcatagc actaaccgta atgaaatctg aaaactctcg gtaataaata
     2941 gaatttgata ttaacaagag gttaaggata atatagacga tccaagagct gatataaaag
     3001 gccctagtat tcttgatata aagggtaaat cccaatagta acaaagctag agggattggg
     3061 ttaataattg ttagaaagac ctgataggca tttcccaaat ctagtgaaaa gtcagcatgg
     3121 taagcccata gggtttttat ccaaaagcag aagagaagcg ttagcacaaa gcctaatctt
     3181 gtattgataa agcttgtgat aaatgtttta aaa
//
LOCUS       DARYYD010000101         3098 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.102, whole genome shotgun sequence.
ACCESSION   DARYYD010000101 DARYYD010000000
VERSION     DARYYD010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3098
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.102"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..1398)
                     /locus_tag="TV188_001911"
     CDS             complement(<1..1398)
                     /locus_tag="TV188_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014622863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1535226.1"
                     /translation="MFYLKLAWNNLRKSLSVTAPFLLASTVLYMLNCIVLIIMMSPVS
                     ESMRHGFMLLGLAIFVLIIFATIMEIYSYNFLLKQRSREFGLYNILGMNKKQVGLVST
                     IELVFMYLGTVVVGSILSAIFSHVFYLIFANLVGAVHLELQINPVAFIYTTLIFAAIF
                     GLLEVVGLIKIRKTSPLMLFRHKEQGEKEPKGNLLLAALSIILLSIGYYISLSSTKLT
                     ALDTLYRFFIAVIIVIIGTYLFYISFMTWHLKRRRQNKAYFYQPEHFVSTSQMIFRMK
                     QNAVGLANITLLAVMAFVAIATTTALYANSEAMSNQLFPKNTHINFDNSEIDNQKEVF
                     NRLIVEKTNKPASDFLVYYSSMVSFEVSQKETIVVTKESLLNPSPVTTGYVYLVTQDD
                     FRALGNQLPELKDNQTAFFKQRGDSQLRQLDILGKSYTNVKNLTSLRSISDDKGIISD
                     GDTVIGHIETKKEYLR"
     gene            complement(1401..2153)
                     /locus_tag="TV188_001912"
     CDS             complement(1401..2153)
                     /locus_tag="TV188_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1535227.1"
                     /translation="MLLEINHLEKVFRTRFSKEETRALQDVDFKVDKGEFIAIMGESG
                     SGKTTLLNILATLEKPTKGSVLLNGTDITKIKEGDLANFRLQNLGFVFQDFNLLDTLS
                     IRDNIFLPLVLNRKPFKEMERRLNIIAPKLRIETLLDKRPFEISGGQKQRVAIARSLI
                     TNPQLLLADEPTAALDYRNSEDILNLFEAINLDGQTLLMVTHSANAASHAKRVLFIKD
                     GRIFHQIYRGNKTNLEFSKDISIAMAGLLGGE"
     gene            2484..2963
                     /locus_tag="TV188_001913"
     CDS             2484..2963
                     /locus_tag="TV188_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEL1535228.1"
                     /translation="MAKKIKKTLGTVGKLFSIIPDTTEIIGKTIDNTRPIIEKHMEQK
                     HEKEMQLTLLDDVINLPVDKAQKHLEQLGFVVALLPVKPSKKWIHASLNEVVSMSPKP
                     GKHKLGSLVKLYYVTVDVLEKSQAILDQETLKAVERNQKIADTIEAVKQIKLPFKKR"
BASE COUNT          996 a          570 c          578 g          954 t
ORIGIN      
        1 tcggaggtat tcctttttag tttcgatatg acctataaca gtatcaccat cactaatgat
       61 tcccttatca tcactaatac tcctaagaga tgttaaattt ttgacattgg tatatgattt
      121 gcccaaaata tccagctgtc gtaattgact atcccctctt tgcttaaaga aggcagtctg
      181 attgtccttt aattcaggca attgattgcc caaggcgcgg aaatcatctt gagtgactaa
      241 gtagacatag cctgtagtga ctggactagg atttagcaag gattctttgg ttactacaat
      301 ggtttctttt tgggatactt caaaagaaac catgctacta taatagacta gaaaatccga
      361 ggcaggctta ttggtctttt caacaataag tctgttaaaa acctcttttt gattgtcaat
      421 ctctgaatta tcaaaattaa tatgagtatt tttaggaaaa agctggttag acattgcctc
      481 gctattagca taaagcgcag ttgttgttgc tattgcaaca aaggccataa cagctaagag
      541 ggtaatattt gccaagccta cagcattttg cttcattcta aaaatcatct gagaggtgct
      601 gacaaaatgc tctggctggt aaaaataagc cttgttttga cgacgacgct ttaagtgcca
      661 agtcataaag gaaatgtaaa agagataggt cccgataata acgataataa ctgctataaa
      721 aaaccgatat aaagtgtcta atgctgtcag ctttgtcgat gataaggaga tgtaatagcc
      781 aatactaagc aatatgatgg ataaggctgc tagtaataaa ttaccctttg gctctttttc
      841 accctgttct ttatgacgaa agagcattaa gggagaggtc tttctgattt taatcaagcc
      901 aacaacctct aataaaccaa agatagcagc aaagattaaa gtggtgtaaa taaaagcaac
      961 gggattgatt tgtaattcta aatggactgc tccgaccaga ttagcgaaaa tcaaataaaa
     1021 gacgtgtgaa aaaatagctg ataggatact tcctacgact actgtcccta agtacataaa
     1081 aacaagctcg atcgttgaga ctaaaccaac ctgcttttta ttcattccca aaatattgta
     1141 cagaccaaat tctcgacttc tttgctttag taaaaaatta tagctataaa tctccataat
     1201 agtggcaaag atgattaaaa caaagattgc tagtcctaat agcataaacc catgtctcat
     1261 cgattctgat acggggctca tcatgataat caagacaata caattgagca tatataaaac
     1321 agtgcttgcc agtaaaaaag gagctgtgac ggataaggac tttcgtagat tattccaagc
     1381 tagtttgaga taaaacatct ttattcacct cctaaaagac cggccatggc aatcgagatg
     1441 tctttgctaa attctaaatt cgttttattt ccacgataga tttggtggaa aatacggccg
     1501 tccttgataa acagtactcg cttagcatgg ctagcagcat tggcagagtg tgttaccatc
     1561 aagagtgtct gaccgtctag gttaatggcc tcaaaaagat tgagaatatc ctctgaattg
     1621 cggtaatcaa gtgctgctgt tggttcgtca gctaataata attgcggatt ggtgattaag
     1681 cttcttgcaa tagcaaccct ttgcttttga ccaccagaaa tttcaaatgg acgtttatct
     1741 aaaagcgttt caatgcgcag cttaggggca atgatgttga gccgtctttc catttcttta
     1801 aatggcttac ggtttaaaac aaggggtaaa aagatattat ctctgatcga tagggtgtct
     1861 aggaggttaa aatcctgaaa aacaaagcct aggttttgaa gtcggaaatt agctaggtca
     1921 ccctccttaa tttttgtaat gtcagtgcca ttcaataaaa cagatccctt ggttggtttt
     1981 tccagagttg ccagaatatt taatagggtt gttttccctg agcctgactc tcccatgatg
     2041 gcaataaact cacccttgtc aaccttaaaa tcaacatctt gtaaggctct agtttcttcc
     2101 tttgaaaagc gtgtccgaaa aaccttctct aaatgattaa tttctaataa catatgaaac
     2161 tcctttgtgt ctattatact cttttagctt taaatatagc cactatcgtg acgtatttag
     2221 ctagtgatgc atttagtgcc ttttgtcagc cttaaccact ccttctttca tgaagcagcc
     2281 cagctctcaa caagaatcgt cttagctgac tgaacctatt gctctaaact cttttttctt
     2341 tacagcttat agtttaccct aattaatagt ctggttagct tacaagattt gatgggtgac
     2401 ttacagattt gtaagtttta taacatcatt tttcttatca ttttgatata atgaaaggag
     2461 aattctattt aggagaagcg tcaatggcta agaaaatcaa aaaaacgcta gggactgtcg
     2521 gaaagctgtt ttccattatc cctgatacca ctgaaattat aggaaaaacg atagataaca
     2581 cccgtcccat tatcgaaaag catatggaac aaaagcatga aaaggaaatg cagctaacgc
     2641 ttttagatga tgtgattaat ttacctgttg ataaagcgca aaagcatctg gaacagctag
     2701 gttttgttgt cgcactattg ccggtcaagc ctagtaaaaa atggatacat gctagcttaa
     2761 atgaggttgt ttccatgtca cctaagcctg gaaagcataa gctgggaagc ttagtaaagc
     2821 tttattatgt tactgtagat gtccttgaga aaagtcaggc tattttagat caagagaccc
     2881 taaaggctgt cgaacgaaat caaaaaatcg ctgataccat cgaagctgtt aagcaaatca
     2941 agcttccttt taaaaagaga taaggctata ctgtaaaaaa taagctgata ccgttaggat
     3001 cagtttattt tttatgttgt gactttaagt ctatctcgct tagcaggtgc caaacaaata
     3061 aaccacccgt tatgtaccga ccttcaatgg ttaaagtt
//
LOCUS       DARYYD010000102         3087 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.103, whole genome shotgun sequence.
ACCESSION   DARYYD010000102 DARYYD010000000
VERSION     DARYYD010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3087
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.103"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..1241
                     /locus_tag="TV188_001914"
     CDS             <1..1241
                     /locus_tag="TV188_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1535229.1"
                     /translation="ADKEKAETEAKKAKEEAKTAKEAAHQEQEKAKQLEQANQQANQR
                     ANLAEKSKKDLETQKEKLEQEIKEATEAKNKAEQKLKDLQDSASQGSELSKQLLKEKE
                     ELTTKLQELQKQAEEKTTEIEKLKQELEANKQNSGQLGQQEQKLQEQLNKVQKELKQK
                     EMELKQAQEQLKQEQKPHEGGGDSDASKARITELEKQVQTLTKEKADLSSTLESTKAQ
                     LSETQARLSEAQKQLTAAQEKLTTLEAEKTALQHQVETISKQLSETRDLSEKEKAALQ
                     EQINKLKAEIEQKTKEIEALKQGMQSHQGQEKPKDPKTPETPKDPKTPEKNDQPQAPE
                     KRSVPWTALTPAKPIDTTKAPKSSAPSPQTGAATPKKQLPATGDTATPSFFTAAAMAV
                     LASVGVLNLSPRRKKNQNNR"
     gene            1658..2500
                     /locus_tag="TV188_001915"
     CDS             1658..2500
                     /locus_tag="TV188_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002991650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEL1535230.1"
                     /translation="MVSVLSRVIKGIIIALGFILPGVSGGVLAAILGIYERIIAFLAH
                     IREHFVENVLFFLPVGVGGILGIALFSYPVDYLLKHYQVPVLWGFAGAIIGTVPSLIK
                     TSTKTSQRDQVDWLWLVLTFVLSGLGLYFLNDLVGTIPASFTAFVLAGALIALGILVP
                     GLSPSNLLLILGLYSPMLIGFKSLDLVGTFLPIAIGGLLTMLAFSKIMDFALKHYHSR
                     VYHFIIGIVLSSTLLILIPNSSNKEAISYAGAGLGTWLMALLLFGLGVWLGLWMSQLE
                     EKYK"
     gene            complement(2603..>3087)
                     /locus_tag="TV188_001916"
     CDS             complement(2603..>3087)
                     /locus_tag="TV188_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HEL1535231.1"
                     /translation="FKPGEVSFPSGRVEEGETYQQAAIRETVEELNIEPEQVHVWGEI
                     DYLVQPTRSIHCFVAELAIDDWRRLRVNEEVDSLFTVPLEELMAQAPVAYPLQMQSII
                     SSDFPLDRIPNGEQYRLRYMQDQVLLYEHLEKPIWGITAQLTNRFIEIVTEARQHDDI
                     "
BASE COUNT         1039 a          696 c          585 g          767 t
ORIGIN      
        1 cggctgataa agaaaaggca gagactgaag ctaaaaaagc gaaagaagaa gctaagaccg
       61 ctaaagaagc tgctcatcaa gaacaagaaa aagctaaaca attagaacaa gctaatcaac
      121 aggctaacca aagagctaat ctggcagaaa aatctaaaaa agatttagaa actcaaaaag
      181 aaaaacttga acaagagatt aaagaagcta cagaagctaa aaacaaagcc gagcaaaaat
      241 taaaagacct acaagattca gctagtcaag gcagtgaatt gtctaaacag ctgttaaaag
      301 aaaaagaaga attaacaaca aaacttcaag agcttcaaaa acaagctgag gaaaaaacaa
      361 ctgaaattga aaagctaaaa caagagcttg aagctaataa acaaaacagt ggtcagctag
      421 gtcaacagga acaaaagctt caagagcaat tgaataaggt tcaaaaagag ctgaaacaaa
      481 aggaaatgga gttaaaacaa gctcaagaac agctgaaaca agaacaaaaa cctcacgaag
      541 gtggcggaga ttctgacgct tccaaagcaa gaatcactga gctagaaaaa caagttcaaa
      601 cactaaccaa ggaaaaggca gatctgtcat caacccttga gtcaacaaaa gctcaattgt
      661 cagagactca agcaagacta tcagaagctc aaaaacaatt gactgctgct caagaaaagt
      721 taacaacact tgaagccgag aaaacagcgc ttcaacatca agttgagacc atttcaaaac
      781 agctatcaga aacacgtgac cttagcgaaa aggaaaaagc agcactccaa gagcaaatca
      841 ataagctaaa ggctgagatt gagcaaaaga ccaaggaaat tgaagcctta aagcaaggca
      901 tgcaatcaca tcaaggtcaa gaaaaaccaa aggatccaaa aactccggaa acaccaaagg
      961 atccaaagac tcctgagaaa aacgatcagc cacaagcgcc tgaaaaacgt agtgtccctt
     1021 ggactgctct tacaccagct aagccaattg acactaccaa agctcctaag agctcagcac
     1081 caagcccaca gactggggca gcaacaccta aaaaacaatt accagcaact ggtgatacag
     1141 cgacacctag cttctttacc gctgctgcta tggcagtatt ggctagcgtc ggtgtcctaa
     1201 atctctcacc tagacgcaaa aagaatcaaa acaaccgtta atgtagagac tctcatatct
     1261 ggattgaata acagcaaacc cgacatgagc aaaaacaaat gtctaaccaa aaatcactga
     1321 cattagtact ttaaccaaag cctttgagtc aagctaaaca ggctgtcctg cctattggct
     1381 tgactcgttt tgtgattgtg aaacacacca aggtcaaacc taccttgtcc tccattttaa
     1441 acctactctt ttctcccata cccactttag cttacgcaag aaggtgccta atcatcactt
     1501 ttggtagctt cgatgctcta tataaatgga tcaacaaaga taaatcatac aaaactgcga
     1561 gttgttccta tagtcacgat agctcttaca gatatgaaaa gtaaatacag ctattaaaaa
     1621 tatggtacaa taggggtacg atttttagga ggcatgtatg gtttcagttc tttcacgagt
     1681 gattaaggga ataattattg cgcttggctt tattttaccg ggagtatctg gaggagtatt
     1741 agccgctatc cttgggatct atgagcgtat cattgccttt ttagctcata tacgtgagca
     1801 ttttgttgag aatgttctct ttttcctgcc tgttggggtt ggtggtattt tagggattgc
     1861 cctcttttct taccctgttg actatctgct caagcactat caggtaccag tcttatgggg
     1921 cttcgctggg gccatcatag gaaccgtacc tagcctgata aagacttcga caaaaacatc
     1981 tcagcgtgac caagttgatt ggctctggct agtattaacc tttgtcctat caggactggg
     2041 actttatttc ttaaatgatc tcgttgggac aatacctgca agctttaccg cctttgtcct
     2101 agctggtgcc ttgattgctt taggtatttt ggtacctggt cttagcccgt ctaatctttt
     2161 attaatttta ggactttact cacccatgct gattggcttt aaatcacttg atttggtagg
     2221 aaccttttta cccattgcta ttggtggctt attaaccatg ctagcttttt ccaagattat
     2281 ggattttgct ctcaagcact accattcacg cgtttaccac tttattatcg gtatcgtcct
     2341 atccagcacc ctgcttattt taattccaaa tagcagtaat aaggaagcta tctcttacgc
     2401 cggtgcaggt cttggcacct ggctaatggc tctgctatta tttggccttg gtgtctggct
     2461 tggtctatgg atgagccagc ttgaggagaa atacaaataa cactcgatac accagcaagt
     2521 acctctaaca gcagcattaa gatcaaaaaa acgaatgact agctctcagc cttatcacca
     2581 gctgtgacta gcattcgttt ttttatatgt catcatgctg tcttgcctct gtcacgattt
     2641 ctataaaacg gttcgtcaat tgagcagtta taccccagat aggcttttct aaatgctcat
     2701 agagtaatac ctgatcttgc atgtacctca acctgtactg ctctccatta gggatacgat
     2761 ccaacggaaa gtctgacgag attatcgatt gcatttgtaa aggataagca acaggagctt
     2821 gcgccatgag ctcctccaaa ggcaccgtaa acaagctatc aacctcttca ttgaccctaa
     2881 gccttctcca atcatcaata gccagttccg caacaaagca atgaatgcta cgagtcggct
     2941 gaactaaata gtcaatctcc ccccaaacat gaacctgctc aggctctata ttgagctcct
     3001 ctaccgtctc acgaatagcc gcctgctgat aagtctcacc ctcctccacg cgcccactag
     3061 gaaaagaaac ctcccctggc ttgaatg
//
LOCUS       DARYYD010000103         3061 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.104, whole genome shotgun sequence.
ACCESSION   DARYYD010000103 DARYYD010000000
VERSION     DARYYD010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3061)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3061)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3061
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.104"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..310
                     /locus_tag="TV188_001917"
     CDS             <1..310
                     /locus_tag="TV188_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="4-phosphopantetheinyl transferase family
                     protein"
                     /protein_id="HEL1535232.1"
                     /translation="KELGIDIEKVNDGFAFEDILENCFTSREIKNIGSNIPMFYRYWT
                     AKEAYLKYEGYGLIRNPKEIEVIYIDNQRIKIEDKVKRSNKDLIAFSISSKYFGAICI
                     "
     gene            319..1902
                     /locus_tag="TV188_001918"
     CDS             319..1902
                     /locus_tag="TV188_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017767101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HEL1535233.1"
                     /translation="MNIELKENLEKNYDDNVWEHVTLGEFVANCAETYKDKTAIVDGE
                     LNLSYDELDKLSNKYANGLLKAGFKKGDKIVLQLPNCYEFIVISFAMFKTGIIPIMSL
                     PAHRKNELKGIIEKSEAVAYISKDKYLGFSYVDMVRDMKSELNTNLEIYILGESEEYK
                     NFSSLIENDCFYKYPDVDYRSIGLLLLSGGTTGIPKLIPRRHCDYIYVAKKTTDRCNV
                     NQESVYLASLPIAHNFPLGCPGIMGTFAKGGKVVLCNVTSPDEILPLIEEEKVTITGF
                     VPAIANICMDYLEYEEYDLSSLEVIQVGGSVLEPWLAEKIEKVFDVKLQQIFGIAEGL
                     ILTTNEEDNDKIRWQTQGKPISEHDEILIVDEQGKIVGIEEYGELIVRGPYTIYGYYN
                     LPEVNETCITQDCYFKTGDKARKLKDGNYQIVGRIKEIINRAGEKITPLELEEILLTH
                     ENINSVQVVGLPDRLQGESIAVFILNGDKELTLEEVRKFLISNNVADFKLPDTVKYID
                     AWPLTALGKIDRNKLKETF"
     gene            1917..>3061
                     /locus_tag="TV188_001919"
     CDS             1917..>3061
                     /locus_tag="TV188_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="HEL1535234.1"
                     /translation="MELNNIKERAKELVKDWLKSIFVEKVVSENENLIEKGLSSIQVM
                     QLSGKLKKTGIKISFAKLMEEPNLSKWYELIDKSRVKSDKNIESSIIQSDESKFDLTD
                     VQYSYLIGREDDQILGGVGCHAYLEIDGENIDEDKLKEAWNKLQYRHPMLRTKFTKDG
                     KQEILYKPYSEEIEVFDLSDLDEETLHLKLVEIREQKSHRKLNVNQGQVAGVALAKFS
                     DEKSRIFFDVDLLVSDVMSMSIMIKELAELYSGVELDNLNEYTFKDYMQNGIGESIND
                     ADKEFWEQKINSFEIERPNLPLRKQPEQIKETKFTRRKRIIKKSEWETIKDIAASYRS
                     TPSMVLLTAYALVLERWCNQDKFFINIPLFNRDLENENLKEMVADFT"
BASE COUNT         1172 a          346 c          646 g          897 t
ORIGIN      
        1 gaaagagctt ggaatagaca ttgaaaaagt gaatgatggc tttgcgtttg aagatatact
       61 tgaaaattgc tttacatcca gagagattaa gaatataggc agtaatatac caatgtttta
      121 tagatattgg acagcaaaag aagcctacct aaaatatgaa ggatatggtc ttataagaaa
      181 tccgaaagaa atagaagtta tttatatcga caatcagaga ataaaaattg aagataaggt
      241 aaaaaggagt aataaagatt tgatagcatt cagcatttca tcgaaatatt ttggagcaat
      301 ttgcatatag gaggaagtat gaatatagaa ttgaaagaaa atttagaaaa aaattatgat
      361 gacaatgttt gggaacatgt gaccttggga gagtttgttg cgaactgtgc ggaaacgtat
      421 aaagataaaa cagcgattgt agatggagaa ttaaacttat cttatgatga gcttgataaa
      481 ctttcgaata agtatgctaa tggactactt aaagcaggtt ttaaaaaagg agataagatt
      541 gtattacagc ttccaaattg ttatgaattt atagtgatat cttttgcaat gtttaaaaca
      601 ggaattattc cgattatgag tttgcctgca catcgaaaga atgaattaaa gggtattata
      661 gaaaagtctg aggcggtagc atatatttca aaggataaat atttaggttt ttcatatgtg
      721 gatatggttc gggatatgaa atctgaatta aatacgaact tggagattta tattcttgga
      781 gaaagtgaag aatataaaaa tttttcgtca cttattgaga atgattgttt ctataaatat
      841 ccggatgtcg attacaggag cataggatta ttgttattat ctggcggtac aacaggaata
      901 ccgaaactga ttccaagaag acattgcgat tatatctatg ttgcaaagaa aacgacggac
      961 cggtgtaacg taaatcagga aagtgtatat cttgcttctt tgccaatagc tcataatttt
     1021 cctttggggt gtccagggat aatgggtact tttgcaaaag gcggaaaggt ggttttgtgc
     1081 aatgtgacaa gccctgatga aattttacct ttaattgagg aagaaaaggt tacgataaca
     1141 ggatttgttc ctgcaattgc caatatttgt atggattatt tagagtatga agagtatgat
     1201 ctttcctctt tggaggttat acaagtcgga ggttcagttt tggaaccttg gttggcagaa
     1261 aaaattgaaa aagtttttga tgttaaacta caacagattt tcggaatcgc tgaaggattg
     1321 atcttgacaa caaatgaaga agataacgat aaaataagat ggcaaacaca aggcaaacca
     1381 atcagtgaac atgatgaaat actgattgtg gatgaacaag gaaaaattgt agggattgaa
     1441 gaatatggag aacttatcgt tagaggtcct tataccattt atggttatta taatcttcct
     1501 gaagtaaatg aaacatgtat aacacaagat tgttatttta agactggtga taaagcacga
     1561 aaactaaaag atggtaatta tcaaattgtc ggaaggatca aagaaatcat caatagagca
     1621 ggtgaaaaga taacaccact tgaattagaa gaaattttgc ttactcatga aaatatcaac
     1681 tcggtacaag ttgtagggct gccagatcgt ctgcaaggag aatccattgc tgtatttatt
     1741 ttaaatggag ataaggagct tacactggaa gaagttagaa aattcttgat ttctaataat
     1801 gtggcggatt ttaaattgcc ggatactgtt aaatatattg atgcgtggcc attaacagct
     1861 ttagggaaaa tagatagaaa taaattaaaa gaaacttttt aaaggaggat tttggaatgg
     1921 aacttaacaa tataaaagaa agagctaaag aattagtaaa ggattggttg aaaagtatat
     1981 ttgtagagaa agtagtttca gaaaatgaaa atttaattga aaaaggttta agttccattc
     2041 aagtcatgca actgtctgga aaattaaaga aaacggggat aaaaatttcg tttgcaaaac
     2101 ttatggaaga accgaatttg tccaagtggt atgaacttat tgataaatcc agagtgaaaa
     2161 gtgataagaa tatagagtca tcaattatcc aaagtgatga aagtaagttt gatttaacag
     2221 atgtccagta ctcctattta atcggaagag aagatgatca gattttaggt ggcgtgggtt
     2281 gccatgcata tcttgaaata gatggagaaa atattgatga ggataagtta aaagaggctt
     2341 ggaataagct tcaatacaga catcccatgc ttagaacaaa atttacgaaa gacgggaagc
     2401 aggaaatatt atacaaaccg tacagtgaag aaatagaagt ttttgattta tctgatcttg
     2461 atgaagaaac gctgcatcta aaattagtag aaattagaga acaaaaatct cataggaaat
     2521 taaatgtaaa tcaaggtcag gttgcaggag tagcactagc aaaattttca gatgagaagt
     2581 caaggatatt ttttgacgta gatttgcttg tatccgatgt aatgagcatg agtattatga
     2641 ttaaagaatt agctgaactt tattcaggag tagaacttga taatttgaat gagtatacgt
     2701 ttaaggatta tatgcaaaac ggaattggcg aatcaatcaa tgatgcagat aaggagtttt
     2761 gggaacaaaa aataaattcc tttgaaatag aaagaccgaa cttaccatta aggaaacagc
     2821 cggaacaaat taaagaaacg aagtttacaa gaagaaagag aattattaaa aaaagtgaat
     2881 gggaaaccat aaaagatata gcagcatcgt atcgaagtac accatctatg gttcttctaa
     2941 ctgcctatgc tcttgttctt gaaagatggt gtaatcagga taaatttttt atcaatatac
     3001 cgctatttaa tagagattta gaaaatgaaa atctaaaaga aatggttgct gattttacaa
     3061 a
//
LOCUS       DARYYD010000104         2983 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.105, whole genome shotgun sequence.
ACCESSION   DARYYD010000104 DARYYD010000000
VERSION     DARYYD010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2983
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.105"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            1..1152
                     /locus_tag="TV188_001920"
                     /pseudo
     CDS             1..1152
                     /locus_tag="TV188_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893534.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="Dam family site-specific
                     DNA-(adenine-N6)-methyltransferase"
     gene            complement(1173..2786)
                     /locus_tag="TV188_001921"
                     /pseudo
     CDS             complement(1173..2786)
                     /locus_tag="TV188_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677638.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
BASE COUNT         1023 a          590 c          395 g          975 t
ORIGIN      
        1 ggctttaaaa gcaatggaag atttaattgc taatattaat gctagtcata tcattctaag
       61 ttacaatacc gagggtatta tatccgaaga agatttaaca cttttacttc aacgatattc
      121 gttcaataat caaattgatg tgaaacggat tccttaccga aaatatcaat ctaagaaaaa
      181 atctcagaac aaagacttat acgaacttct tttttatatt caaagaaagc cgataaataa
      241 tcgcttcaaa tcacaaacta aaaaaaaggc agccatcatc agtcaaaaaa agtatataaa
      301 aagcccatta aattatatcg gtggaaaata tcgactgcta aatcaaatca ttccaatttt
      361 tccccgacat atcaatacat ttgttgatat gtttagtggg gggcaaacgt tggtatcaat
      421 gttcctgcta aaaaacacat ctttaatgat atgaactatc gcattaatga catgtttcga
      481 tattttcaat cacatgaccc acttgagata cttgaacaaa ttgagcatcg aatttcagaa
      541 tatcaactca gcaagaccaa tgaacaaggc tttttaacat tccgaaaaca ttataatact
      601 catccaaatc cactagactt atacgtacta tcgtcttata gctataacta tcaatttcgc
      661 tttaataact caatggaatt caataaccca ttcggcagaa atagaagtca ttttagtgaa
      721 aatatgaaat ccaatctact caattttgta gctcgactac accgtttaga tgccactttc
      781 tctgatcaat ttttctcaga ttttgatatt tctacattat caatagatga ttttgtttat
      841 cttgatcccc cctacctcat aacgactggc agctataatg atggaaatcg tggcttcaca
      901 aactggggcg aaaaacaaga aattgaaatg tatcaattaa taagagacct taacaagaaa
      961 caaattaagg ttgcacttag taatgttctt gttcataaag gaaagcacaa tgatttactt
     1021 gagcaatttg ttcaagatga aagtctatat ctcaccactt taaattacaa ttataaaaat
     1081 gcttcataca acacaagaaa agaagatagc attgaagtat tgattaccaa ttataaacca
     1141 aatccaaaat aataaaagca tagttgaatt agctatgctt ttacaaattc aatttcttta
     1201 ttttgaaaat aagatggtaa atcggaaata tgcagttgtc ctttaagaac caaatctgct
     1261 cccaaaagca attgctctac attgagggct gctcccttaa tttgtgtttc attagaggta
     1321 taatcaagct gctcttgaaa ttttccaatg aatttacttg acacccacat aaaataaaac
     1381 tcttcttgtg gaatcgtatc tggaaaagct tcccaccact ttatcggatt acgattttca
     1441 tctcgtcgct tattatcctc aatataccga atcatttcat cagcctgatt gatagattta
     1501 gaataacctt ttccataagc ctttgtatct acaatcacac caaaacgatc ttgatagagt
     1561 aaaccatctg gctttctgcc accacctaaa agcttagaat gcaatctata tacatttcta
     1621 aataattcca ttgtaacaat ttcaaaatct cgatttcgct taccatcgta agcaatatca
     1681 agcaattcaa tatatttcat tggtaaatta gtctctttta aaaattttgc cttacgcttt
     1741 tctgcctgct catcctttaa ttcttgtgta atttctagtt caggaataga aaaatcgttg
     1801 atcttatcct tcaaagaaac tctattgcta gaaatatcta tcctcaaacc aaaataattc
     1861 aatccttgaa tatctgataa gataatctcc agttcatcgt aaaaaccctt agcccttagt
     1921 ttatctaata gaatagccaa agaattagtt tcttggagaa acttgacgat ataagctctc
     1981 cgagtacgaa catactcgcg attattgcca tgagttgcaa aaaattccca catcacaaat
     2041 ttttcaagct tgctatgctt agaatccccc tgagcttgtc gtaaagcatg aagaccacga
     2101 ccattaattt tataaccttg aaatccatct ttttcaccat tagtaaaggt acgcttaatc
     2161 gtttgtgaat caaccaaacc aacatttttt agccaattac aaataccgcg tgcatattta
     2221 tcacttgttc cttctatatc agctttaata agttttttct ctgatttagt ggcagatcct
     2281 aaccaatcaa acataatatc ttcattatag gaagtaaagc ctttttcacc acgaaaacca
     2341 agctgctcac ctaaataata tttagtacaa taagtaccgc tatcagccaa taaagataag
     2401 atttgtgtag ctggcgggta tgacaacagt gcctttctta aaatagcagt ttcttcttcc
     2461 gaattaatta ttgccctaga aaaatgcaac cccttcgaag taattgaaaa catatccgtt
     2521 tctctatcta ccgacacaaa attcaggcta acagcccatc ttaaaaaacc atctgatgtc
     2581 caattatccg tccaagtttt acctgtattt tttgcctgtt gaggtacgat gctgatttga
     2641 atcaaagaat ctgccattgc atctgaacgc tttcggggag atttgttatt cttatccttt
     2701 gatgttccaa ctaattctaa atatgaaaat gattgaatcc cattaatcag tttgtttctg
     2761 agtgattctc gtggtacttc aaagaaatct gtacccaacc ataagttctt attttcataa
     2821 gagctcctta atcttatact tattatcttt attatagcat ataattaatc cttccagtta
     2881 gcattatcac aaagcaacaa catttcttat ttaatggggc tactatgtag ctattttaat
     2941 acatgttttt acctcacgaa aacaccccca cttgtcaagt ctg
//
LOCUS       DARYYD010000105         2968 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.106, whole genome shotgun sequence.
ACCESSION   DARYYD010000105 DARYYD010000000
VERSION     DARYYD010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2968
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.106"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(1..234)
                     /locus_tag="TV188_001922"
     CDS             complement(1..234)
                     /locus_tag="TV188_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HEL1535235.1"
                     /translation="MVFDYSKLSGRIVEKFGTQYNFALALGLSERSLSLKLNNKVDWR
                     SKEIAQACQELDINENDVGEYFFKQNVHIHEQN"
     gene            442..1209
                     /locus_tag="TV188_001923"
     CDS             442..1209
                     /locus_tag="TV188_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003052464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1535236.1"
                     /translation="MSERNLRQVDILEKSKPFQKQLGVKMGRSTLSQYVSGKSVPAQR
                     QLYLLSKTLNVSEAWLMGYDVAIERIPDEKRRATTEISNQPEIVSIYNQLEQPRQEKV
                     LSFANEQLEEQNKVVSTHEELFSVQGVTYAAAASGFGRGFEADEYDTYTVYTDEEPPR
                     YDYAIGIRGDSMLPKYEQGDMLYIVDRGMSTYNGQLCIVVHNGQTYFKKVYTEEDGLR
                     LVSLNKKYNDIFIDYPPAEDTYIKIYDVVGSFTPVEM"
     gene            1223..1453
                     /locus_tag="TV188_001924"
     CDS             1223..1453
                     /locus_tag="TV188_001924"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535237.1"
                     /translation="MTTFTLTIDEKNKYIADYFKRNNIDDSQLTFEQLLTVLEDAEDY
                     AAGMAVLMEQKDNPDYKTYTLQEVADELGITL"
     gene            1453..1740
                     /locus_tag="TV188_001925"
     CDS             1453..1740
                     /locus_tag="TV188_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEL1535238.1"
                     /translation="MYKIEFDPKVKKQLKKLDKTASSKIIRWLYANVDGTSLPRLHGK
                     ALTGDLAGLWRYRIGDYRVICDIQDDKLVILAVHIAHRKQVYKLKLPNNKR"
     gene            1753..2079
                     /locus_tag="TV188_001926"
     CDS             1753..2079
                     /locus_tag="TV188_001926"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535239.1"
                     /translation="MYFDEFKEYVENNSRAHDYFFERALDYQNAKNARRTPAHRRWKE
                     QKVLKEVETMWTNVVKQLYDNIKLNGKFRKRFMHQEEIDEWVSFMNEHEILESFADSM
                     AEIEFE"
     gene            2145..2570
                     /locus_tag="TV188_001927"
     CDS             2145..2570
                     /locus_tag="TV188_001927"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535240.1"
                     /translation="METEKINNVNILRSNNSRLSGYATSASYPLILPIIVEFELYNIK
                     QSKTYLFQITATKINDRRQNNHIKDLLSLSSNQTTVTISAERHNTFFPYEGYGTVATK
                     LDFSFNIDSPGDYCIALTLLDSEGSLLDKHSNYYIFGEE"
     gene            2672..2938
                     /locus_tag="TV188_001928"
     CDS             2672..2938
                     /locus_tag="TV188_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535241.1"
                     /translation="MSQEIYSKSEIDLKFENLETKIDSKFDLLMQKMDDGFEKQRLNT
                     EKMLSDFKLNLVTDQQKNKKEFMYWAIGIIIALAGIAFPIWFGK"
BASE COUNT         1059 a          503 c          556 g          850 t
ORIGIN      
        1 ttagttttgt tcatgaatat gaacattttg cttaaaaaaa tattctccta catcgttttc
       61 gttgatatct aactcttgac aagcttgcgc aatttctttg cttctccagt ctactttatt
      121 attaagtttt aaagatagcg agcgctcaga tagccctaaa gccaaggcaa agttgtactg
      181 tgtgccgaac ttctcaacga tccttccgct gagttttgaa taatcaaaaa ccataggaac
      241 ctcctttctt ttttgttcat gttcatgaac tttatgcttt tatgttacac tttgttttga
      301 actttgtcaa tacacaaagt tcattttttt gaattttttt attgaacttt tgttcaagat
      361 gttttataat taacctataa acatcgaaag gaatctactt ttatgcaatg tagttctact
      421 tcaaatagat taaaacaact gatgtcagaa agaaatttaa ggcaggttga tattttagaa
      481 aaatcaaaac cttttcagaa acaattgggg gtaaagatgg gcagaagtac tctttcgcaa
      541 tacgttagtg gcaaatctgt tccagctcaa cgacaactct atcttttatc taaaaccctt
      601 aacgtaagcg aggcatggct gatgggatat gatgtagcca tagagcgcat acctgatgaa
      661 aaacgtagag ctacgacaga aatatctaat caacctgaaa tagtgtccat ctacaaccaa
      721 ctagaacaac ctagacaaga aaaagtcctc agcttcgcta acgaacaatt ggaagaacaa
      781 aataaagttg tttctacgca tgaagaatta ttttcggttc aaggcgtaac ttacgcggca
      841 gccgcaagtg gctttggtcg tggatttgaa gcagatgaat atgacacata tactgtctac
      901 actgacgaag aacctcctcg ctacgactac gctattggaa ttcgaggaga cagcatgcta
      961 ccaaaatatg agcaagggga tatgctctat attgtagata gaggtatgtc aacatataac
     1021 ggtcaactgt gtatcgttgt tcacaacgga caaacctatt ttaagaaagt atatacagaa
     1081 gaagacggac ttagattagt atctctcaac aagaaatata acgatatttt tattgactac
     1141 ccaccagcag aagatactta tatcaaaatc tatgacgttg tcggcagttt tacacccgta
     1201 gaaatgtaaa ggaggagata ttgtgacaac atttacactt acgattgatg aaaaaaataa
     1261 atacatagct gactacttca agagaaataa tattgatgat agtcagctca cgttcgagca
     1321 gctccttact gtcctagaag atgcagaaga ctatgcggca ggtatggcag tgttgatgga
     1381 acaaaaagac aatcccgact ataaaaccta cacacttcaa gaagtagctg acgaattggg
     1441 tattactcta tgatgtacaa aatagaattc gaccctaaag tcaaaaagca gctaaaaaaa
     1501 ttagataaaa cggcatcttc aaaaattatc cgttggcttt atgctaatgt ggacggtact
     1561 tctctaccta gactgcacgg aaaagcgtta actggtgacc tagctggatt atggcgctac
     1621 cgtataggag attatagggt catctgtgat atacaagatg ataaacttgt tatcctagct
     1681 gttcacatag cccatagaaa gcaagtttac aaactcaaat tgccaaacaa taaacgatag
     1741 aggtttaaag taatgtattt tgacgaattt aaagagtatg tagaaaacaa tagccgtgct
     1801 catgattatt tctttgaaag ggcacttgat tatcaaaatg ctaaaaatgc taggcgaaca
     1861 cccgctcata ggcgatggaa agagcaaaag gtactcaaag aagttgagac tatgtggacc
     1921 aatgttgtca agcaacttta tgacaacatc aagttaaacg ggaagttcag gaaacggttc
     1981 atgcaccaag aagaaattga tgagtgggtt tccttcatga acgaacatga aattttggaa
     2041 tcattcgcag atagcatggc tgaaatagag tttgagtagg aacgtcgcta acggagcgtt
     2101 gatcaaagaa gaattagagt ttttaattag ttaaggagat aagcatggaa actgaaaaaa
     2161 taaataatgt aaatatttta cgaagtaata actcaagact ttcgggatac gcaacaagtg
     2221 cgagttatcc ccttatattg cccattatag ttgagtttga attgtataat attaagcaaa
     2281 gcaaaaccta tctatttcaa ataacagcaa ctaaaataaa cgatagaaga caaaataatc
     2341 atatcaaaga cttactatca ctatccagca atcagactac tgtcaccatc tccgcagaga
     2401 gacataatac attttttccg tatgaaggat acggaacagt ggcaacaaaa cttgatttct
     2461 cgtttaacat agacagtccg ggtgactatt gcattgcgct tacacttttg gatagcgagg
     2521 gatctttatt agataagcac tcaaattatt acatttttgg agaagagtaa ttatgagtga
     2581 atatcttaca ctatataaac ccgaaacctc caacattgat gccaaaaata atggtataat
     2641 agacttagaa aagagtcagg aggaatctat tatgtcacaa gaaatttata gcaaatcaga
     2701 aatagatttg aagtttgaaa atcttgaaac gaaaattgat agcaaattcg atttattgat
     2761 gcagaaaatg gatgatggtt ttgaaaaaca acgattaaat acagaaaaaa tgttgtcaga
     2821 tttcaagcta aatctagtga ctgatcaaca gaaaaataaa aaagaattta tgtattgggc
     2881 tatcggtatt attattgcct tagcaggtat tgcttttccg atttggttcg ggaaataaaa
     2941 aaagccccac gctctcaaag tttggcga
//
LOCUS       DARYYD010000106         2950 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.107, whole genome shotgun sequence.
ACCESSION   DARYYD010000106 DARYYD010000000
VERSION     DARYYD010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2950
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.107"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(64..1230)
                     /locus_tag="TV188_001929"
     CDS             complement(64..1230)
                     /locus_tag="TV188_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEL1535242.1"
                     /translation="MKYNKTKYPNIFTYDTKKGKRYYVRRGYYLKGKKKEATKSNLKT
                     LQEARAALTEIEQKIENNDFAYNKNLTVDQYWEIYVDNRLKAGVWSPDTYVERTNIFK
                     NHIGPKFGNKKMNAINRIEYENYINNLLNTNSRSTVKHIYDVFSIMLNHAVKNKMLDD
                     NIIKFIDIGDSEIKPINKRRSMQEFKAWDKIARKMLDDYDYAMVRITYLGLRRSEVAG
                     IKLGNITFNDKDCAVVKIDESRTRGRKDGGGLKTAYSERYVYLDFETSQLLKKAIDTS
                     IKIAVCNDRILNKADFLFLGDDEKVKPSFVGKPIGSHYIYCLFKKINKNCDVNFTPHM
                     MRHFFATQGQIAGVPIEHMAAALGHSNNYMTSQYTHIKDEVSENVTAAFMGSIK"
     gene            complement(1434..1976)
                     /locus_tag="TV188_001930"
     CDS             complement(1434..1976)
                     /locus_tag="TV188_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HEL1535243.1"
                     /translation="MNLDTVLQQMKECGAYDTWGTKKEVKALPEILSDDEIIQYATSG
                     FVNGNTVLVVLTQKRILFIDKGMLYGIRSTEIPLDMVNSVSYSKGLILGAIAVMNGAT
                     KIEISNIAKDTCPVLTEKIKDCVEQYKYNLYQHQSPQKTATVGSEDAVAEIRKFKKLY
                     DEGILTEEEFIAKKKIILGI"
     gene            complement(2002..2787)
                     /locus_tag="TV188_001931"
     CDS             complement(2002..2787)
                     /locus_tag="TV188_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEL1535244.1"
                     /translation="MNDKELALYIGSKIKELRKNKGLTQKELAILVNMGDTTIANYEK
                     GFRTPKKNTLFKLANALSVTIDELFPPINKKNKENIVHLKQQSNTTEINNKVALLDKE
                     LKEPRHSYWVKYGENLLSEQNTVGHSKNTVEEPQAAYYTYNYYDHAASAGTGQYLSDV
                     QVETIELPVDYDADFVIPVYGDSMEPEYHSGDYVFVKLSVELTDGDIGVFEYYGDAYI
                     KQLLINDEGAFLHSLNSKYEDIPVDRDSDFRIIGEVVGSYSEK"
BASE COUNT          817 a          543 c          484 g         1106 t
ORIGIN      
        1 gtcataaaaa gtaacaaaaa tcataaaaag taatattttg tcggggacta tgtcggggaa
       61 tttttatttt atactgccca taaaagctgc tgtgacattt tcacttacct cgtcttttat
      121 gtgggtgtat tggctagtca tgtaattatt tgaatgacct aaagccgctg ccatatgctc
      181 aattgggaca ccggctattt ggccctgtgt agcgaaaaaa tgcctcatca tgtgcggagt
      241 aaaattaacg tcgcaatttt tattgatttt tttaaataag cagtagatgt agtggctacc
      301 gattggtttt cctacaaaag atggctttac tttttcgtcg tctcctaaaa ataggaaatc
      361 agccttgttt aagatgcgat cgttgcacac ggctattttg atagatgtat caatggcttt
      421 ttttagcagt tgtgatgtct cgaaatctaa atacacatat cgttccgaat aagctgtctt
      481 taggcctccg ccatcttttc tacctctggt ccttgattcg tctatcttta cgactgcaca
      541 atctttatca ttaaaagtta tattccctaa ttttatgcca gctacctcgc ttctacgcaa
      601 tccaagatat gttatcctaa ccattgcgta gtcataatca tcaagcattt ttctggcaat
      661 tttatcccaa gctttaaact cttgcattga tctacgtttg ttgataggtt ttatttcgct
      721 atcgccaatg tcaataaatt tgatgatatt atcgtctagc attttatttt tgacagcatg
      781 atttaacata atactaaaaa catcatatat gtgctttact gtacttcttg agttggtatt
      841 gagcagattg ttaatgtagt tttcgtattc tatacggttt atagcattca tttttttatt
      901 gccaaacttt gggccgatgt gatttttaaa gatattagtg cgctcaacgt atgtgtcagg
      961 agaccacact ccagctttta atctattatc aacgtatatt tcccagtact gatcaactgt
     1021 caaatttttg ttataagcaa aatcattgtt ttctattttt tgctcaattt cagtaagtgc
     1081 agctctggct tcctgtagcg tttttaagtt gctttttgta gcctctttct ttttaccttt
     1141 taagtaataa cccctacgga cgtagtagcg tttacctttc tttgtatcgt aggtaaagat
     1201 atttgggtat tttgttttgt tgtatttcat tcttaaatcc tttcgttttt ttgacttttg
     1261 gacgaggtcg tttgaaagga tattggcatc accacctttg tgtgatataa ttttaggtac
     1321 aagaaaacga cctttttaat ggttgtttct tatacggttt cgcctcacgc tcagactcgc
     1381 caaagtttga gagcgtgggg ctttttttat tttttaacgg ttaactttac accttaaatt
     1441 cctaaaatta tttttttctt agctataaac tcttcctctg taagaatgcc ttcatcataa
     1501 agttttttaa acttacggat ttcagcaacg gcatcttccg agcctacagt tgctgttttc
     1561 tgaggcgatt gatgttggta cagattatat ttgtattgtt ctacacaatc ttttattttt
     1621 tcggtaagta cagggcaagt gtccttggca atattagata tttcaatttt tgtggctccg
     1681 ttcataacag ctattgcgcc aagaattaaa cctttagagt atgagacgct attaaccata
     1741 tcaagaggaa tttctgtcga tctaattcca tataacattc ccttatcgat aaataaaatt
     1801 cgtttttggg tcaatacaac aaggacagta ttgccgttta caaacccaga tgttgcgtat
     1861 tggataattt cgtcatctga caaaatttct ggcaaagcct ttacttcttt ctttgtcccc
     1921 caagtgtcgt aagccccaca ttccttcatt tgttgcaaaa cagtatctaa attcataata
     1981 aaactcctta taaaaatatt cttatttttc agaataactc cccacaactt caccaataat
     2041 tctaaagtcg ctatctctat ctacgggtat atcttcatac ttgctattta aactgtgcag
     2101 aaatgccccc tcgtcattta taagtagctg tttgatataa gcgtcaccat aatactcaaa
     2161 aacgcctata tcgccatctg ttagctctac ggatagctta acaaagacat agtccccaga
     2221 gtgatattcg ggttccatgg aatctccata aacaggaata acaaaatcag cgtcataatc
     2281 aactggtaat tcaattgttt ctacttgcac atcacttaaa tattgaccag taccagcaga
     2341 agcagcgtgg tcgtagtagt tgtaggtgta gtaggcggct tgtggttctt ctactgtatt
     2401 cttactgtgt cctactgtgt tttgttcaga taaaagattt tcaccgtatt ttacccaata
     2461 actatgacga ggttctttga gctctttgtc taataaagcg actttgttat taatttctgt
     2521 ggtgttagat tgctgtttaa gatgtacgat attttcttta ttttttttat ttataggagg
     2581 gaagagttca tctatagtaa cagatagggc attcgcaagt ttaaacaaag tatttttttt
     2641 aggcgttcta aacccctttt catagttagc aattgtagta tcccccatat taaccaagat
     2701 tgctaactct ttttgagtta gccctttatt ttttctcagt tccttgattt tagagccgat
     2761 atataaagct agctctttat cattcatttg aattcttctt tctttttatt taataatagt
     2821 ataacacata aattcacgtt ttgaaaagtt tttttgtttt ttcgaaaaaa aacagttgac
     2881 acttcacgaa aagtgaagta caatataatc aagcttaagg aattaagcaa aataaaaact
     2941 cccaagaggg
//
LOCUS       DARYYD010000107         2913 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.108, whole genome shotgun sequence.
ACCESSION   DARYYD010000107 DARYYD010000000
VERSION     DARYYD010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2913
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.108"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..162
                     /locus_tag="TV188_001932"
     CDS             <1..162
                     /locus_tag="TV188_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1535245.1"
                     /translation="GSYEANTDSQYTLYLLGKGGNLGISGTEMKGVRVIVSWEKPKDK
                     IDSWLVFND"
     gene            520..735
                     /locus_tag="TV188_001933"
     CDS             520..735
                     /locus_tag="TV188_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002838961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HEL1535246.1"
                     /translation="MDFFVQAVNVLKILVMAIGAGLGAWGVINLLEGYGSDNPGAKSQ
                     GIKQLMSGGGIVLIGLKLIPLLANVLR"
     gene            735..1598
                     /locus_tag="TV188_001934"
     CDS             735..1598
                     /locus_tag="TV188_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535247.1"
                     /translation="MFDLFGKIEEFFKDIMIDIIKDNLSAMLVDINDKVGTVAGEVGK
                     TPSSWNSEVFTFIKSINTNVVLPIAAIILTAILCIELIQVVMRKNSMHDTDTFEFFKY
                     IIKMWIAVWLVSHAFDFSMAVFDVAQSMIGKAAGVVGTSANITPGNFDAMVEALKTKE
                     LGTLIGIALETGLVKFSLTILSILITVILYGRMIEIYIYCSVAAIPFSTMGNKEWSNI
                     GTNYIKSLFALGLQGLFILIFFGIYAVLVKTVNFTDIHTSILQVLAYGLILGVMMMKS
                     GSIAKAILNSH"
     gene            1671..2165
                     /locus_tag="TV188_001935"
     CDS             1671..2165
                     /locus_tag="TV188_001935"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HEL1535248.1"
                     /translation="MNKINKKTRILIGAGSALSIGTIITVLLKKKTKKLSDLEEDDFD
                     FDFDEIEEDSCVNDKFATENDKDDTVKGEIDFLVDESKTENEKQEEFRDLSVKVMDLL
                     LKEVISMSETLNLVKRDIDRIGEVKALVEELENCKEEIISLWEHMEKLSDLREEITGK
                     KNRG"
     gene            2169..2579
                     /locus_tag="TV188_001936"
     CDS             2169..2579
                     /locus_tag="TV188_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009531364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HEL1535249.1"
                     /translation="MAYVKIPKDLTKVKTKVALNMTKRQLIGFSIAGLIGFPVYMLCK
                     NFLSTDISMIIMSIVVLPVLFVTLYEKDNLPFEKHLAYILRFHKSKKIRLYKARSIYH
                     TERAKKQDIGNKNKASGRRKKVEQRQKKKTGTTN"
     gene            2539..>2913
                     /locus_tag="TV188_001937"
     CDS             2539..>2913
                     /locus_tag="TV188_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HEL1535250.1"
                     /translation="MNKDKRKKQEQRIKKDELELRKNRKELSELKKTGKKKTKSKTKG
                     KSSKKNGWFPFFMKEEKKETVQDTIPYKRMLKDGICQIEKNKFNKTIRFLDINYRLME
                     EIDQEGIFSEFSSFLNFFDSSVE"
BASE COUNT         1125 a          343 c          597 g          848 t
ORIGIN      
        1 ggctcttatg aagcaaatac tgattcgcaa tatacattat atttattagg aaaaggcgga
       61 aatttaggca tttccggtac ggagatgaaa ggagtacgtg ttattgtaag ttgggaaaaa
      121 ccaaaagata aaatagatag ttggcttgta tttaatgatt aaaaatacaa tatttgtaat
      181 aaaagttgta aaataataat ttattgttag gggaggattt atactaatgt gtaaatcctc
      241 ttttttatat aaagcataaa ataatgaaag tgaaattaag ctataaaata ttatgaaaaa
      301 agatacttgg aagtgtaaat gtaagatgta tatttctaaa aataatagac attaatttaa
      361 aagagagatg ggataaataa aatgaaaaat ataataaaat caataaggat aagaagtcca
      421 actttaagaa aattgaatag caaaagttta acgattggaa gagaagattt ccagtcgttt
      481 ttttatgaaa ataagtaaaa taatgaggag gaataaatta tggatttttt tgtacaggca
      541 gtaaatgtgc ttaaaatttt ggttatggca atcggtgcag gacttggtgc atggggagtt
      601 atcaacttac ttgaaggata cggatcagat aatcccggtg ccaagtcgca aggaatcaag
      661 caattgatga gcggtggagg aattgtttta atagggctga aactaattcc gctacttgct
      721 aatgtcttga gataatgttt gatttatttg gaaagataga agagtttttc aaggatatta
      781 tgattgatat tattaaagat aatctttctg caatgcttgt ggatattaat gataaagtag
      841 gaaccgttgc aggagaagtg ggaaagactc cgagttcttg gaactcggag gtcttcacct
      901 tcattaaatc aatcaatacc aatgttgttt tacccatagc agcgataatt ctaaccgcaa
      961 tactttgcat agaactgatt caggtggtaa tgagaaaaaa ttctatgcac gatacggata
     1021 cctttgaatt ttttaagtac attattaaaa tgtggatagc tgtatggctt gtgtctcatg
     1081 cgtttgattt ttcaatggca gtctttgatg tggcacagtc catgatagga aaggcagcag
     1141 gtgttgtggg gacaagtgcg aatatcacac cgggaaattt tgatgctatg gtagaagccc
     1201 ttaaaacaaa ggaacttgga acactcattg ggattgcact ggagacggga ttagttaaat
     1261 tttctttaac gattctatca atcttaatca ctgtaatcct atatggaaga atgattgaga
     1321 tatatatcta ttgctctgtt gcggcaattc cattttctac gatgggaaat aaagaatggt
     1381 caaatatcgg aacaaactat ataaaaagtc tatttgccct tggacttcag ggacttttca
     1441 tcctaatatt ttttggaatt tacgcagtct tagtcaaaac cgtaaacttt acggatatcc
     1501 acacaagtat tttacaggta ttggcatatg gattgattct tggagtaatg atgatgaaat
     1561 ccggaagtat agcaaaggcg attttaaaca gtcactaaag gactttagtt caaaatgagc
     1621 aaaagttgat gaaataatca gaacaaaaaa tataattatt ggaggtaaga atgaataaaa
     1681 taaataaaaa aacaaggatt ttgataggag caggctcagc cctttctatc gggacaatta
     1741 ttacagtgct attaaaaaag aaaacgaaaa aattatccga tcttgaagaa gatgattttg
     1801 actttgattt tgatgaaata gaagaagatt cttgtgtcaa cgataaattt gctacagaaa
     1861 atgataaaga tgatacagta aaaggagaaa tagatttttt agtagatgaa tcaaagacgg
     1921 agaacgaaaa gcaagaagag tttagagatt tatcggtaaa ggtaatggat cttcttctaa
     1981 aagaagtaat ttcaatgagt gaaaccttaa atttggtaaa aagagatatt gatagaatag
     2041 gtgaagtaaa agcattggtt gaagaactgg aaaactgtaa agaagaaatt atctcacttt
     2101 gggagcacat ggaaaagtta tccgatttaa gagaagaaat taccggcaaa aagaatagag
     2161 gttaggctat ggcttatgta aagataccaa aagaccttac aaaagtaaaa accaaggtag
     2221 ccctgaatat gacaaaaagg cagcttatag gttttagcat agcagggctt atcggttttc
     2281 ctgtatatat gctgtgtaaa aattttctta gtacagatat ttccatgatt ataatgagta
     2341 tagtagttct acctgttctt tttgtaacgc tttatgaaaa ggacaattta ccttttgaaa
     2401 aacatttagc atatatcctc aggtttcata aaagtaaaaa gatcaggcta tataaagcga
     2461 ggagcattta tcatacagag agagcaaaaa agcaagatat aggaaataaa aataaggcaa
     2521 gcggaaggag gaaaaaagtt gaacaaagac aaaagaaaaa aacaggaaca acgaattaaa
     2581 aaggatgagt tggagcttag gaaaaataga aaggagctat ccgaacttaa aaaaacagga
     2641 aagaaaaaaa caaagtctaa aacaaaaggg aaatcatcga agaagaatgg gtggtttcct
     2701 ttttttatga aagaggagaa aaaagaaacc gtacaggata ccattccata taagcgaatg
     2761 ttaaaagacg ggatttgtca aattgaaaag aataagttta ataaaaccat tcgatttttg
     2821 gacattaact atcgcttaat ggaagaaata gaccaagagg gaatattttc ggaattttct
     2881 tcttttctaa atttctttga ctcatctgtg gaa
//
LOCUS       DARYYD010000108         2652 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.109, whole genome shotgun sequence.
ACCESSION   DARYYD010000108 DARYYD010000000
VERSION     DARYYD010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2652
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.109"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..509
                     /locus_tag="TV188_001938"
     CDS             <1..509
                     /locus_tag="TV188_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="SPASM domain-containing protein"
                     /protein_id="HEL1535251.1"
                     /translation="EVIDFCFKQGLLRIQLSSIFSSHNRLLVSDEKYAAHYNKLIEKF
                     SCLGVQFLTSPFCHPWSLAIKHGIEYHSPLYCPAQKTEFEIDMYGDVYPCPFLHDKIH
                     LMGNLISDDFETIWYSGVEQLNRRAWSSNDSCKNCKLFNDCGGGCYAMAFVSQLEYDK
                     RCILHANQ"
     gene            496..756
                     /locus_tag="TV188_001939"
     CDS             496..756
                     /locus_tag="TV188_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017649764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEL1535252.1"
                     /translation="MQISKNWFIRFEPNFQTTQNTILFNKVSGELFEVTEVYYDCINS
                     LRIGVDFQALLMEKYAVNAGDVIDVEDTILKNLISLGVILNE"
     gene            749..1648
                     /locus_tag="TV188_001940"
     CDS             749..1648
                     /locus_tag="TV188_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002900052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1535253.1"
                     /translation="MSDITIRHVKKSFHHQVVLDVPSFDVKRGEIVAIVGANGAGKST
                     LIKMISGLMLQDTGSVLVYHHKNTSAAIHRDVKFVLESGRGYYEYLTANQNIDYFLHL
                     NNLSRSQVKEELAELCQKLAFNPYTDRLVSELSQGTRQKLSLIIALLCQPKVLCLDEP
                     TNGLDVVAKKQFATLLLELSQKKQTIILMTTHDIFFVKELSARICVMSKGKIKKQGSF
                     SEIFGENNTWMKYRIGIPKFEKAIFDQLFPFLAYQVEDERLVVEVTDSQTKHHIFEHF
                     EIIFFEEVEKSIEELLYEVITDD"
     gene            1638..2378
                     /locus_tag="TV188_001941"
     CDS             1638..2378
                     /locus_tag="TV188_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002909393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1535254.1"
                     /translation="MMIKEIQRELKRQLQEMMQFKFNLFFANFGILIMVSSYLHYFED
                     TQSQFLLLCLLFTWYFTSHSLTHPIFFIEDDLYDRTLISVIQSSKSVFHVLMLKIIVQ
                     LLVDLVKAIPIVIMLSLLNNIDFPESSLRVMGSFVACFLTVISTYGLGFCLSSLCFVF
                     NRTSSVTALISYFMLYFTGILTPLDGSLGLIGKMFPYYALRNAIMSPSYQSVCWIVAY
                     GMIYWSVGTLLFSRALTMAKKRGSLFHV"
     gene            complement(2434..>2652)
                     /locus_tag="TV188_001942"
     CDS             complement(2434..>2652)
                     /locus_tag="TV188_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEL1535255.1"
                     /translation="MSRKGNSPDNGMMESFFGILKSEMFYGLETTYQSLNELEQAITD
                     YIFYYNNKRIKAKLKGLSPVQYRTKSFH"
BASE COUNT          810 a          391 c          527 g          924 t
ORIGIN      
        1 atgaggtcat agatttttgt tttaaacaag gattgttacg tatccaatta tcttctattt
       61 tttctagtca taatagatta ttagtatctg atgaaaaata tgctgcacat tataataaat
      121 tgatagagaa atttagttgt ttaggtgttc aatttttaac atcacctttt tgtcacccat
      181 ggtctcttgc aataaagcat ggaattgaat atcattcccc actttactgt ccagctcaaa
      241 aaacggaatt tgagattgat atgtatggag atgtctatcc ttgtccattc ttacacgata
      301 aaattcactt aatgggaaat ttaatttctg atgattttga aactatttgg tactctggag
      361 tagaacagtt aaatagaagg gcttggtcaa gtaatgatag ttgtaaaaat tgtaaattat
      421 ttaatgattg cggtggaggg tgctatgcca tggcatttgt ttcacagcta gaatatgata
      481 agaggtgtat attacatgca aatcagtaaa aattggttta ttagatttga acctaatttt
      541 caaacgacac aaaatacgat attatttaat aaagtaagcg gagagctgtt tgaggtaaca
      601 gaagtttact atgattgtat caattctctg agaattggtg tcgattttca agctcttctg
      661 atggaaaagt atgctgtcaa cgcaggggac gtgattgacg tagaagatac gattttaaaa
      721 aatctaatat cgctaggagt aattcttaat gagtgacatc actatacgcc atgtcaagaa
      781 aagctttcat catcaggtag tcttagatgt gcctagtttt gatgtaaagc gtggagaaat
      841 tgttgctatc gttggtgcaa atggtgcagg taaatcaact ttgatcaaaa tgatctctgg
      901 tttaatgctg caagacacag gatctgtttt ggtttatcat cataaaaata cttcagcagc
      961 tattcatcgt gatgtgaaat ttgtcttaga aagtggtagg ggctattacg agtatctgac
     1021 tgcaaatcaa aatattgatt actttttaca tttgaataac ctgtcacgta gccaagtcaa
     1081 agaagaattg gcagagttgt gccaaaaatt ggcttttaat ccctatactg atcggttggt
     1141 ttctgaatta tcccaaggca caagacaaaa attgtctttg attattgctc ttctttgtca
     1201 gcccaaggtt ctgtgcttag atgagccaac aaatggtcta gatgtggttg caaaaaagca
     1261 atttgcaacc ttgttgcttg agcttagtca aaaaaagcaa acgattatcc tgatgacgac
     1321 tcatgatatc ttttttgtaa aagagctatc agcaagaatt tgtgtcatga gtaaagggaa
     1381 gatcaaaaaa caggggagtt tttcagaaat tttcggagaa aacaatacgt ggatgaaata
     1441 tagaatcggt atccctaagt ttgagaaggc tatttttgat cagttatttc ctttcttagc
     1501 ttatcaggta gaagatgaga gattagtcgt cgaagtgaca gatagtcaga caaaacatca
     1561 tatctttgag cattttgaga ttatattttt tgaagaagtt gaaaaaagca tcgaagagct
     1621 attatatgag gttattactg atgattaaag aaatacaaag ggagttgaaa agacaattgc
     1681 aggagatgat gcaattcaaa ttcaatttat tttttgcaaa ctttggtatt ttgatcatgg
     1741 tgtcatctta tcttcactat tttgaagata cgcagagtca gttcttgtta ttatgtctat
     1801 tattcacttg gtattttacg agtcatagcc tcacacatcc aatctttttt attgaagatg
     1861 acctttatga tagaacgttg atcagtgtta ttcaaagcag caagagtgtt tttcatgtcc
     1921 tcatgcttaa aattattgtt caactattgg tggatttagt taaggcaata cctattgtta
     1981 ttatgttatc actccttaat aatattgact ttccagaaag tagcttgagg gtgatgggaa
     2041 gctttgttgc ctgttttttg acagtcatta gtacatacgg tcttggcttt tgcttatcca
     2101 gtctctgttt tgtgtttaat cgtacctcca gtgttactgc gttaatttct tatttcatgc
     2161 tatactttac cggcatacta acgccattag atggctcact tggtcttatt ggaaaaatgt
     2221 tcccttatta tgctttgaga aatgctatta tgtctccttc atatcagagc gtatgttgga
     2281 ttgtggctta cggtatgata tattggtcgg tcggtacgtt attgttttct agggcattga
     2341 caatggctaa aaaaagaggg agtctttttc atgtttagtg aaatgaaacg atatatgact
     2401 ttgtactgac ccccaaaagt tggacacgac atattagtga aaggatttag ttctgtattg
     2461 cacagggcta agtcctttta gctttgcttt aatgcgtttg ttgttgtagt aaaaaatgta
     2521 atctgtaata gcttgttcaa gctcattaag ggattgataa gttgtctcaa ggccgtaaaa
     2581 catctcagat ttgagaatac caaagaagga ctccatcatc ccattatctg gactatttcc
     2641 cttgcgagac at
//
LOCUS       DARYYD010000109         2637 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.110, whole genome shotgun sequence.
ACCESSION   DARYYD010000109 DARYYD010000000
VERSION     DARYYD010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2637
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.110"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(215..1729)
                     /locus_tag="TV188_001943"
     CDS             complement(215..1729)
                     /locus_tag="TV188_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEL1535256.1"
                     /translation="MLDYYLERDIVERKLILAVLLTEKEITLDSLCSQTSITPRKAKE
                     YLNQINALFDKDLSITVLKSGITCEFDPNNKEKYFHSIYASSDTLKMLKFLLTDNYRT
                     KCLTTFIRRQFISKSKAYHLVNKLKGYLQSIHLDIDDYRVIGDEYRIRYLIAMLHKEY
                     GFAVYEMTPKDMEIIHAFIFLTPTRLKPTVFLDKKFYLFDILLMLSWKRQNYDVSLPQ
                     LTLFDRLKELSIFEQISCYAKQEIETRTQVVFNSGDLDYLYLVYLTVDSSFLMHYWND
                     KQLRLVYNILEEDPLYKELVNRLEMLFGRQLHLRDQMYFLLPFFRRCLFQLHDLISFQ
                     DYYSKRYQGSQLLLEKVEEQIKDWLMVSYQSETLSPGHLHFMCLHLEQMLELSLPPVE
                     VIIVENKRALGDVLSYFVISSIPSYKVNITRINMLTDSLENYEQAPDFVITSDNILPF
                     LEEQQVFPDKSVLIGMSMDYIKEQGKTVVKSILNFHRKHYEQLLEQLLIGDRVE"
BASE COUNT          958 a          521 c          404 g          754 t
ORIGIN      
        1 tataacaaaa atccacttga aaggcttatc acaagtggat ttttcagaaa tattgtacca
       61 aataggcacg agctattgat tgctgctatt tagcataggt gttatcacga tcagcagtaa
      121 gccaatcaaa acaggtatcg ctaaagcaaa tcctcacaaa aaatggtcca aagaaaaacc
      181 tagcagcctt ataccacttg cttagcaaaa aaacttactc taccctatct ccaatcaaga
      241 gctgctctaa aagctgctcg taatgcttac gatgaaagtt cagaattgat tttaccactg
      301 tttttccctg ctccttaatg taatccatgc tcataccaat taagacgctc ttatctggaa
      361 atacctgctg ctcctcaaga aaaggcaaaa tattatcact cgtaatcaca aaatcaggag
      421 cctgctcata attttccaga ctatctgtta gcatgttgat acgagtaata ttaaccttat
      481 aagaaggaat acttgagata acaaagtaag acaagacatc acctaatgct ctcttgtttt
      541 caacgatgat gacctctaca ggcggcaagg acagctcaag catctgctcc aaatgaaggc
      601 acataaaatg caggtgccct ggtgagagcg tttctgactg gtagctaacc atcagccagt
      661 ccttgatttg ctcctcaacc ttttctagca gcagctgact gccttgatac ctctttgaat
      721 agtaatcctg aaagctaatc aaatcatgca attgaaagag acatcttctg aaaaagggaa
      781 gcaaaaaata catctgatcc cttaaatgaa gctgacgacc aaacaacatt tccaagcgat
      841 taacaagctc cttatacagc ggatcttctt ctaagatatt gtagacaaga cgtaattgct
      901 tgtcattcca ataatgcata agaaaagaac tatcaactgt aagataaacc aagtaaagat
      961 aatctaagtc accagaatta aacacaacct gagtacgtgt ctcaatttct tgcttagcat
     1021 agcaactgat ttgctcaaaa atagataatt cttttaaacg atcaaataaa gtaagctgtg
     1081 gtaaggatac atcataattc tgcctcttcc aagacagcat gagtaaaata tcaaaaagat
     1141 aaaatttctt gtccaagaaa acagtgggct ttaaccgcgt aggggttaaa aaaataaagg
     1201 catgaataat ttccatatcc ttaggtgtca tctcataaac agcaaaccca tactccttat
     1261 gaagcatggc aattaagtag cgaatccggt actcatcccc tataacccgg taatcatcga
     1321 tatccaaatg aatggattgc aggtagccct ttagcttatt gacaagatga taggcctttg
     1381 atttggaaat aaactgtctt ctgatgaaag ttgtcagaca ctttgtcctg taattatccg
     1441 tcaacagaaa cttcaacatt ttaagcgtat cagatgatgc ataaatactg tgaaaatact
     1501 tctccttgtt attaggatca aactcacagg taatgcctga cttcaataca gtaatagaca
     1561 ggtctttgtc aaatagtgca ttaatctgat taaggtattc cttagccttt cgaggggtta
     1621 ttgacgtctg cgagcacaat gaatcaagtg taatctcttt ttctgtcaat aagacagcca
     1681 atattagttt tcgctcaaca atatctcttt ctaaatagta atctaacaaa ataatctctc
     1741 tccttattag tttgtatgac catatacatt ttagttgata ggatttaaaa gtcaactaaa
     1801 aaaaatacac aaaaaataac gactgcttcc tttcaaggat catctgaaaa tgataaataa
     1861 aaaagactga aaatatttta taaaataacc tataagagta tacagtcaat agcttataaa
     1921 atcaagcctt atgataatac cttgacaaat tagccttttt tagacatttt atgagaatgt
     1981 cattttacta acataatcag aatattagta acttaattaa agataaaaaa accgaaataa
     2041 atgcaaaaac caagacaaaa atcgccacat gatactactg tcaacttaaa gactattctt
     2101 tgaaaaatta tctttataaa ttcattattt ttaataaaaa taagacaaaa gatgagaaaa
     2161 atagccaaaa agctactaat ctcagcagcc ttgcaaactg gcagcgacat tataggtaaa
     2221 atgataacgc tgagaaacaa gcccttctct ttttatacat attatacata atccctacaa
     2281 taacagtagt tatggtttta catcgtcaaa tcattagaga aaccatatat gctaaactgt
     2341 catagcctcc actactctct aggagatgat agagatgacc cgcttagtaa caagcctaaa
     2401 agtatcttgc aatagcttct aaagctttgc ttgcagtaaa aaaggtgagc gttctagcct
     2461 aaatgcttgt cacacataag caagcctcag acagcctcaa aataagcttt tccatagcaa
     2521 gtctgtcacg ctggacggga taggggtctt atatctcatt aatatataaa ataaatctct
     2581 cggccacata atacattgtt acctacagac gaattcctca atttagataa cctaagt
//
LOCUS       DARYYD010000110         2499 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.111, whole genome shotgun sequence.
ACCESSION   DARYYD010000110 DARYYD010000000
VERSION     DARYYD010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2499
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.111"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(45..1403)
                     /locus_tag="TV188_001944"
     CDS             complement(45..1403)
                     /locus_tag="TV188_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HEL1535257.1"
                     /translation="MILKSGIRNNHIKWIFTMLPLFVSVLPFISNIEKVFILILISIF
                     LLASNIIPAWYTSILFMTACMIGNIAEKQVILSGITSGAAWLVISGVIIGAAVKHTEL
                     DRLLARFFIPVCMGKYSKVLFGTILLGVVLIFLMPSAMGRVVLLLPILNALSLELGYE
                     KGSKEWEGIVMSGVLATYIPAFYVLPSNVPNNVFTGAILSLYSINISYSRYFLLYFPI
                     LGVGKILILYFTMRLFYRRCKDSICVSKKAIDITKEQKLLIVLLFITLSFWMTEHIHK
                     VPTGWTGMATALIVMLPNSNFMEKQPLRKINFEPFFYVAGIISLGNIAKSSGLANVIA
                     VHLINIVSLETASAFNVLTFFVVLCIILGFIVTLPGVPAVVTPLIDNISGVSNVSKTF
                     LCHIEVIGFSSVFFPFQAPPLMVVLQNENLSKARMTIYCSIVSAIGLLLLLPLALYWK
                     ML"
     gene            complement(1811..2041)
                     /locus_tag="TV188_001945"
     CDS             complement(1811..2041)
                     /locus_tag="TV188_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002846351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535258.1"
                     /translation="MKNIDEKILMTDGEIKQLQNKRKKPIIQSKQEERKKRDRRLYEK
                     GAVNQKILKIIEKREQTEENIEVQEEATDTEE"
     gene            complement(2135..>2499)
                     /locus_tag="TV188_001946"
     CDS             complement(2135..>2499)
                     /locus_tag="TV188_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535259.1"
                     /translation="LIACILFFKKDILQVFPRMDIAWVGFLVVAILLCVSGIWVFSIS
                     GKKQDWINETDERESLITAKANMVGYVIQTTLLGIVFFLLVFMGYLNKVSGFSIIGVV
                     LISGIVSWIYHLYLRKVE"
BASE COUNT          817 a          482 c          315 g          885 t
ORIGIN      
        1 cttctaacta gtatagtacg aggatataat taaatcttcg tcttttacaa cattttccaa
       61 tataacgcta gtggtaacaa caataataat ccaatagctg atacaatcga acaatatatt
      121 gtcattcttg cttttgataa attttcattt tgtaaaacca ccatcaaggg tggtgcctga
      181 aatgggaaaa atacacttga aaaacctata acttcaatat gacataaaaa tgtttttgaa
      241 acattactaa cgcctgaaat attatcaatc aaaggtgtaa ctactgccgg aacacccggt
      301 aaagttacta taaatcctaa tataatacac aatacaacga aaaaagttaa aacattaaat
      361 gcacttgctg tttccaaaga aacaatattg attaaatgca cagcaatgac atttgcaagt
      421 cctgaagatt ttgctatatt ccctaaactt atgattccag ctacataaaa aaatggctca
      481 aaatttattt ttcttaaagg ttgcttttcc ataaaatttg aatttggtaa cattacaatc
      541 aaggcagttg ccattcctgt ccaaccggtt ggtactttat gaatatgttc tgtcatccag
      601 aaagacagag ttataaataa caaaactatt aacaatttct gctcttttgt tatgtcaatg
      661 gcttttttgg acacgcaaat cgaatcttta catcttctat aaaataaccg cattgtaaaa
      721 tataaaatca atatttttcc aactcctaaa atagggaagt acaagagaaa gtatctgcta
      781 taggatatat ttatggagta aagacttaaa attgctccag taaaaacatt atttggaaca
      841 ttggaaggta atacataaaa tgcaggtata taggttgcta aaacccctga cataacaatt
      901 ccttcccatt ccttacttcc tttttcataa cctaattcta aagatagggc atttagaata
      961 ggtaaaagca aaactactct acccattgct gatggcatca aaaaaattag taccactcct
     1021 agcaaaatcg tcccaaataa cactttagaa tatttcccca tgcacaccgg aataaaaaat
     1081 ctcgcaagta atctatcaag ttcagtatgc tttactgccg cccctataat aacacctgaa
     1141 ataacaagcc atgctgcacc tgaagttatc cctgataaga tgacttgctt ctcagctata
     1201 ttccctatca tacaagctgt cataaataaa atgcttgtat accatgcagg aattatattg
     1261 cttgccaaaa ggaagataga tataagaatc aaaataaaaa ctttctctat atttgaaata
     1321 aatggtagta cagatacaaa caacggtaac attgtaaata tccactttat atgattattc
     1381 ctaattccag attttaaaat catcctccat ttttgacctc caactctaat ttatttcata
     1441 gtattatacc atatttattt tcattttata ggtctacctc ttgcttcttt gtctgtgtta
     1501 atcgcttttc ttgtttttat aactgctcta tacaagtctt aactttttct gcctgtttaa
     1561 ttttttctcg tatctctaat attttattgt gtaagctctt tttttctttc ttcatattgg
     1621 cgacttccga ttttcatttg ctaatgacta aggtcttgct ttcgcccaaa tgctctttta
     1681 gatatttctt ggcactctca aataaaataa tctctgctgt atcaacgtta gctgatatgc
     1741 cctctgcaag agccttcgga gaacgcacgc acctgttgag gtgtatatgt acactcttgt
     1801 aaacaaggga ctattcctct gtgtccgttg cttcctcttg cacttctatg ttttcttctg
     1861 tttgttctct tttctctatg atttttagga ttttttgatt gactgctccc ttttcataaa
     1921 ggcgtctatc tctctttttt ctctcttcct gtttcgactg aatgatgggc ttttttcttt
     1981 tgttttgtaa ctgcttgatt tctccatctg tcattaaaat tttttcatct atgtttttca
     2041 ttttctattt tcctctcttt ctgttttgag caacaaaaaa acagtaaacc atttttttga
     2101 tttactgttt tctaataaat attatcttag ttatctattc tacttttcgt aaatataaat
     2161 gataaatcca tgatacgata ccacttatca aaacaactcc aattatagaa aacccagaaa
     2221 ctttgtttaa atagcccata aaaactagaa gaaaaaaaac tattcccagt aaagttgttt
     2281 gaatcacata tcctaccata ttagccttag ctgttattaa ggactctctt tcatcggttt
     2341 catttatcca atcttgtttt ttacctgaaa ttgaaaatac ccatattcca ctaacacaca
     2401 gaagaatagc aacaacgaga aagcctaccc atgcaatatc cattcttgga aatacctgta
     2461 aaatatcttt tttaaaaaat aatatgcaag caatcaagg
//
LOCUS       DARYYD010000111         2473 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.112, whole genome shotgun sequence.
ACCESSION   DARYYD010000111 DARYYD010000000
VERSION     DARYYD010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2473)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2473)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2473
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.112"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            51..1004
                     /locus_tag="TV188_001947"
     CDS             51..1004
                     /locus_tag="TV188_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEL1535260.1"
                     /translation="MNFEKIEQAYELILENSQLIENDLKTHIYDAIVEQNSFYLGAQG
                     ASPQVAKNIETLKALQLTKEEWRQAYQFVLIKAGKTEPLQANHQFTPDAIGFIMLYIL
                     ETLSSQESLDVLEIGSGTGNLAQTILNHSHKSIDYLGIELDDLLIDLSASIAEIMGSS
                     AQFIQEDAIRPQLLKESDLIISDLPVGFYPNDDIASRYQVASSDEHTYAHHLLMEQAL
                     KYLKKDGFAIFLAPVNLLSSPQSHLLKQWLKGYAQVVALITLPEAVFGNPANAKSIIV
                     LCKQSNRFAETFVYPIRDLKSVDNVRDFMENFKNWKRDNVI"
     gene            1064..2263
                     /locus_tag="TV188_001948"
     CDS             1064..2263
                     /locus_tag="TV188_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEL1535261.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEEKVLAQGIIERIGLTDSISTV
                     KYDGKKEEHILDIPDHTEAVKRLLNDLIHFGIIGTYDEITGVGHRIVAGGEYFKESVV
                     VDDKVVEQVEELAALAPLHNPGAAAGIRAFRKILPDITSVCVFDTSFHTTMQKHTYLY
                     PIPQKYYTDYKVRKYGAHGTSHKYVAEEAAKMLGRPLDELKLITAHVGNGVSITANYH
                     GQSVDTSMGFTPLAGPMMGTRSGDIDPAIIPYLIAQDPELKDAADVVNMLNKQSGLGG
                     VSGISSDMRDIEAGLQANNPDAVLAYNIFIDRIKKFIGQYFAVLNGADALVFTAGMGE
                     NAPLMRQDVVNGLSWFGMEIDPEKNVFGYRGDISTAASKVKVLVISTDEELCIARDVE
                     RLKQTIS"
BASE COUNT          730 a          440 c          557 g          746 t
ORIGIN      
        1 tggctagtgg tattcttttc atttcagcct tattttgata tgatagacgt atgaattttg
       61 aaaagattga acaagcctat gagcttatat tagaaaatag ccagctgatt gaaaatgatt
      121 taaaaacgca tatctatgat gctattgttg agcagaattc tttttatctg ggagcccaag
      181 gagcaagccc tcaggttgct aaaaatattg agacgttgaa ggccttgcag ttaaccaagg
      241 aggagtggcg ccaggcttat cagtttgttt tgatcaaggc tgggaaaaca gagccattac
      301 aggccaacca ccaatttacc ccagacgcga tcggctttat catgctttat attttggaga
      361 ccttgagctc acaagagtca cttgatgtgc ttgagattgg cagtggaaca ggtaatttag
      421 ctcaaactat tttaaaccac tcacataaga gcattgatta tttaggcatt gagcttgatg
      481 atttactaat tgatctatca gctagtatcg ctgaaatcat ggggtcatca gcccagttta
      541 ttcaagagga tgctatcaga cctcagctgt taaaagaaag tgatctcatc attagcgatt
      601 tgccagttgg tttttatcct aacgacgata ttgctagcag gtatcaggtg gctagctcag
      661 atgagcatac ctatgcccat catttactga tggagcaagc cttaaagtac ctgaaaaaag
      721 atggctttgc tattttctta gcaccggtaa atcttttgag cagcccacaa agtcacctct
      781 taaaacaatg gctgaagggc tatgctcagg ttgtggcctt gattactttg cctgaggctg
      841 tgtttggaaa tccagctaat gcaaaatcga ttattgttct ttgtaagcaa tcgaatcgct
      901 ttgcagaaac ctttgtttac cccattaggg atttgaaatc tgttgataat gttcgtgatt
      961 ttatggaaaa cttcaaaaat tggaaacggg ataatgttat ttaagagaat tttttgatat
     1021 aatagaaaag cattgcagaa aacgatttca agagaggtaa aacatgtcaa agacaattgc
     1081 aattaatgca ggaagctcca gcttaaaatg gcagctatat caaatgccag aggaaaaggt
     1141 attagcacag ggaattatcg aacgtatcgg tctgacagac tcaatctcta ctgttaaata
     1201 cgatggcaaa aaagaagagc atattcttga tattccagat catacagagg ctgttaagcg
     1261 cttgttgaat gatttgattc attttggcat tattggtacg tatgacgaga tcacaggtgt
     1321 tgggcaccgt attgttgcag gtggtgaata cttcaaggaa tctgtggttg ttgatgataa
     1381 ggttgttgag caggttgagg agttagcagc cttggcaccc ttgcacaatc cgggggcagc
     1441 agcaggtatt cgtgcctttc gtaagatttt gccggacatt acgagtgttt gtgtgtttga
     1501 tacttcgttt cataccacaa tgcaaaagca tacctacctt tatccaattc ctcaaaaata
     1561 ttatacagat tataaggttc gcaagtacgg ggcgcatggg actagccata aatatgttgc
     1621 tgaggaagca gcaaaaatgc tgggtcgccc tctagacgaa ttaaagctca ttacagccca
     1681 tgttggtaat ggtgtgtcta tcacagccaa ttatcatggt cagtcagtgg atacctctat
     1741 gggctttaca ccgcttgctg gtccgatgat ggggacacgc tctggtgata ttgatcctgc
     1801 tattattcct tatttgattg ctcaggatcc tgagctaaag gacgcagcag atgtggtcaa
     1861 tatgcttaac aagcaatctg gattaggtgg tgtgtctggt atttccagtg atatgcgtga
     1921 tattgaggct ggcttgcagg ctaacaatcc agatgccgtc ttagcttaca atatctttat
     1981 cgatcgtatc aagaaattta tcggacaata ctttgcggta ttaaatggtg cagatgcctt
     2041 ggtctttacc gcaggtatgg gtgagaatgc tcccttgatg cgccaagatg tcgtcaatgg
     2101 cttgtcatgg tttggtatgg aaattgatcc agagaaaaat gtgtttggtt atcgtggtga
     2161 tatttcaaca gcagcttcaa aggtgaaggt gcttgtcatc tcaactgatg aagagctgtg
     2221 tattgcgcgt gacgttgaac gcttgaaaca gactatatca taatctgata atatactctt
     2281 agctcagctg atcagtttta aagagtccaa aaaatacttt taattggtac cgacctccaa
     2341 aagttagact taaaggttta acgattggag gtcggtatta ttatatagcc aaatattctc
     2401 aagacaaaga cagccaaaaa atgagacggt cgtaaccgtc tcaaaaaagt ttaatttaat
     2461 taaaaacatt cat
//
LOCUS       DARYYD010000112         2421 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.113, whole genome shotgun sequence.
ACCESSION   DARYYD010000112 DARYYD010000000
VERSION     DARYYD010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2421
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.113"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            67..260
                     /gene="ssrS"
                     /locus_tag="TV188_001949"
     ncRNA           67..260
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="TV188_001949"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            262..334
                     /locus_tag="TV188_001950"
     tRNA            262..334
                     /locus_tag="TV188_001950"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:295..297,aa:Lys,seq:ctt)
     gene            560..1054
                     /locus_tag="TV188_001951"
                     /pseudo
     CDS             560..1054
                     /locus_tag="TV188_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014623587.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(1418..2128)
                     /gene="speh"
                     /locus_tag="TV188_001952"
     CDS             complement(1418..2128)
                     /gene="speh"
                     /locus_tag="TV188_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeH"
                     /protein_id="HEL1535262.1"
                     /translation="MRYNCRYSHIDKKIYSMIICLSFLLYSNVVQANSYNTTNRHNLE
                     SLYKHDSNLIEADSIKNSPDIVTSHMLKYSVKDKNLSVFFEKDWISQEFKDKEVDIYA
                     LSAQEACECPGKRYEAFGGITLTNSEKKEIKVPINVWDKSKQHPPMFITVNKPKVTAQ
                     EVDIKVRKLLIKKYDIYNNREQKYSKGTVTLDLNSGKDIVFDLYYFGNGDFNSMLKIY
                     SNNERIDSTQFHVDVSIS"
     gene            complement(2154..>2421)
                     /gene="spei"
                     /locus_tag="TV188_001953"
     CDS             complement(2154..>2421)
                     /gene="spei"
                     /locus_tag="TV188_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047373492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeI"
                     /protein_id="HEL1535263.1"
                     /translation="VKSRYYLQKHFNIYGYGDVKDFGRSSRFQSGFEEGNIIFHLNSG
                     ERISYNLFDTGHGDRESMLKKYSDNKTAYSDQLHIDIYLVKFNK"
BASE COUNT          835 a          407 c          359 g          820 t
ORIGIN      
        1 atacgatctt tttttcattt tagggcttga aaaattttca aaaagtggta tcataagagc
       61 atagagttat tgctgtggca tacgaattca catctaagtg ttgaccgact atttttttgt
      121 attttaggga aacaaagtct atctctagta tgcaagccgt ttcacgtgga agcaatctga
      181 agagaagtat gttgcccacc tgcttatatc gtgcgggttc aatacaaaac gtgaatcacc
      241 ggtgccaata cagctttcct tacctcctta gctcagttgg tagagcagta gactcttaat
      301 ctatgggtca caggttcgag ccctgtaggg ggtatagtgt aaaaacgaca aaaagccttt
      361 attgcagggc ttttttgctt gcctaaagag ggtttgtccc accatttgtc cccgaaacaa
      421 ttttttatga tatgatgtta aataaagaat ttattacttt ttaaaaagag agctaacaca
      481 tgacaataat ataattaaca caaggtgata caatcggagt attttcacct ccatcacctg
      541 cgacggaatt tggagaaaaa tggctttttt taattattcg caggctttaa cagttggaca
      601 aatagatatt aaaaatgctc gcttaaaagc tggaaaaaca caaaaagaac tcgctaaatt
      661 aataggagtt actaagcaaa caattattaa tgacgaaaag gggactactg aaccttcatg
      721 ggataggctt caagagattg ctacagcctt aaatgttgat attgatacct tatttcccta
      781 caatatgtta ggagaaaaaa gagactttaa gtggatggag cacctagaga gactcgaaaa
      841 taattggctt tatagccgta tggccgagga agaagtatta cttcaaaaaa ttctagattt
      901 tgcaatattt caaaataaat tagataaaaa cactctaaca actaaagaac ttaatcttga
      961 agacaacaac actatgtcca aagaagataa aatttcactc atcatattga aatatgaaaa
     1021 agaaattcaa gaaaaaactc aaaaacttct tgagtttatt cccgaaaaaa cacaaggaac
     1081 aataatggtt acaaagtcga taataaaagc atttgttagt attaaaccgg tattgtatcg
     1141 acacaagaaa cgacaaaagt tctaaactta tgccccaatt ttgccccaat ggttctttct
     1201 tgattctttg gtgaactaaa attattcaga ctcagaaagt tctgccataa catcggatat
     1261 ccgctcgatt gtcacaacct cccaatctct tatctcctca tatattttat attaaaatat
     1321 caataaatat tagcataatt ttaaaacact aaaaatatat cttggtaatt tttactttat
     1381 ttatctattt ttaataaaca gcttcttaaa aatataatta gctgattgac acatctacat
     1441 gaaattgagt tgagtctatt ctctcgttat tggaatatat ttttagcatg ctattaaagt
     1501 ctccattgcc aaaataatac aaatcaaaaa caatatcttt acctgaattt aaatctaagg
     1561 taacagttcc tttagagtat ttttgttccc ggttattata gatatcgtat ttcttaatca
     1621 ataactttct aacttttata tccacttcct gagcggttac tttcggttta ttgactgtaa
     1681 taaacatagg cggatgttgt ttacttttat cccacacgtt tataggaact ttaatttctt
     1741 ttttttctga attagttaat gtaattccac caaacgcttc ataccttttt cctggacatt
     1801 cacaagcctc ttgtgcagat agagcataaa tatctacttc tttatctttg aattcctgtg
     1861 atatccaatc tttctcaaaa aaaactgaca aatttttatc cttgacacta tatttcaaca
     1921 tatggcttgt tacaatatct ggagaatttt ttatactatc ggcttcaatt aagttagaat
     1981 catgcttata aagcgattct agattatgtc tattggttgt attataagaa tttgcttgaa
     2041 caacattgga atataaaaga aatgacaaac atataatcat gctgtagatt ttcttatcaa
     2101 tatgtgagta gcgacaatta tatctcattt tttctcctta agaagtgaga gttttattta
     2161 ttaaatttaa ctaagtatat atcaatatga agttgatcag aataagcggt cttattatca
     2221 ctgtattttt ttagcatact ctctctgtca ccatgtcctg tatcaaaaag attataagaa
     2281 attctctctc cactattcaa atgaaaaata atatttcctt cctcaaagcc agattgaaat
     2341 ctagaggagc ggccaaaatc tttaacatca ccgtatccgt atatattaaa atgtttttga
     2401 agataatatc ttgatttcac a
//
LOCUS       DARYYD010000113         2324 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.114, whole genome shotgun sequence.
ACCESSION   DARYYD010000113 DARYYD010000000
VERSION     DARYYD010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2324
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.114"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(195..1181)
                     /locus_tag="TV188_001954"
     CDS             complement(195..1181)
                     /locus_tag="TV188_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012767009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HEL1535264.1"
                     /translation="MSKKLRNSLARIVVAAFASFAVMAIPTYHHSTVLAKTVSVNQTY
                     GEYKDYYTVIGESNIDQSAFPKIYKTTERVYKGQGTSEKRVTVSDVVYNPLDGYKRST
                     GAYGVVTKDMIDMSKGYREKWETNPEPSGWFRFYNRADNEEISEKEYDSRRTKSYKVT
                     NNVPVVLTTLKGKQYNSHLFVRSHLFADSLGGKSIRKNAITGTQMQNVGTRKGGMQYI
                     EKKVLSHITKNPDVYVFYSAIPEYQGTELLARSVLVSALSSDGVINETVRVFNTADGF
                     NINYEKGGLLTESPVSEIDNIEDSTTDEIENSVDDSEEIVYNDTTTEEEEEN"
     gene            1420..1599
                     /locus_tag="TV188_001955"
     CDS             1420..1599
                     /locus_tag="TV188_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1535265.1"
                     /translation="MLTYDEFKQAIDDGYITGDTVAIVRKNGQIFDYVLPHEEVRSWE
                     VSIEEIVEEVLRELE"
BASE COUNT          704 a          409 c          373 g          838 t
ORIGIN      
        1 ccactaaact gttgtagttg taatggcaat aagctaaaac acatagggaa tacatttctt
       61 aacaacggat attttttctt tttattgata atttgtgtct tgtgctttat gctaggtaac
      121 tattttaaat aaaaaaacaa ccgctcagat taatttctgg gcggtttttg tgtgtctaaa
      181 aattttttga aatcttagtt ttcttcttct tcttcggtag tagtatcgtt ataaactatt
      241 tcttctgaat catccacaga attttctatt tcgtctgttg tagaatcttc aatattatca
      301 atttcactta cagggctttc tgttaagagt ccaccctttt cataattaat attaaatcca
      361 tcagcggtgt tgaaaacacg aacagtttca ttaattactc catcggaaga taaagcagat
      421 actaaaactg atcttgctaa taactcagtc ccctgatatt cagggatggc gctgtagaat
      481 acataaacat caggattctt agtgatatgg cttaaaactt ttttctcaat atattgcatc
      541 ccacctttac gtgttcctac attttgcatt tgagttccag taatagcgtt tttccgtatg
      601 gactttcctc caaggctatc ggcaaagaga tggctacgta caaataagtg actgttgtat
      661 tgtttacctt ttaatgttgt taacactaca ggtacattgt tggtaacttt gtatgactta
      721 gtacgtcttg aatcatattc tttctcacta atttcttcat tatcggctct attataaaat
      781 ctgaaccaac cgcttggttc gggatttgtt tcccattttt cacggtatcc tttagacatg
      841 tcaatcatat cttttgtgac aacgccgtaa gcgcctgttg aacgtttata gccatctaat
      901 gggttataaa ctacatcaga tacggttact cttttttcgc ttgtaccttg tcctttatag
      961 actctctcgg ttgttttata tatcttagga aaagcagatt ggtcaatgtt tgactcacca
     1021 attacagtat aatagtcttt atattcacca taagtctgat ttactgagac tgttttagct
     1081 aagactgtac tgtgatgata agttggaatc gccatcacag caaatgatgc gaatgctgca
     1141 acaactattc tggcgagaga gtttctaagc tttttagaca tatccatgtc ctcctttaat
     1201 tatttacagg ttaagtatac cactttaaat taaaaaaact taaaattaat aaaattaatt
     1261 tgttgccaat attgtactaa aatttctttt tatctaatat tcgtcaatag ttaataagtt
     1321 agtttgtcat aaaatagatg ttatttaatt ttaaataagc tttaaattta attatattat
     1381 ttcctgtaaa atacgaataa taagataagg aggtgcttta tgctaacata cgacgaattt
     1441 aaacaggcaa ttgatgacgg atatatcaca ggagacacag tagcgatcgt gcgcaaaaac
     1501 ggacagattt ttgattatgt attgccgcat gaggaagtga ggtcgtggga ggtgtcaata
     1561 gaagaaatag tggaagaagt gctgcgggaa ttggagtaac attacccgtc aatcacccgt
     1621 ttatttttgt tttttcgtct ttttctatcc tttttatatt ctcaaaacac caacgtttaa
     1681 gtgttttgca aaggttgaaa acggtgaaat aaccaccagc aatcccctcc tctcctttta
     1741 tcctattggt atatcaaggg tttcggagtc ttcgcctgtt tttcacccgt caaatttgag
     1801 attttgaaaa atgcttttga cctgatggtc atttttttct tttaacttat ccaattggtg
     1861 aacatatatt ttaggctcta tcatttctgt agtggattta tccagtatgg aaatgatagg
     1921 gctttttgag tacaaaaaag tcccataaga cttatcatga gaagcactaa caatctcatt
     1981 agaaagtatc ttatggaaca tatcaataat atcacattct gcttcgctat tgtcgggtta
     2041 ataattttat cactttaatt ttttcaatac tttttgacta attagtaaaa ccactactcc
     2101 taaaaatata gtcccaataa agtcataaaa aggacttctt cctgtaaggg caaaccaaac
     2161 gaatcgcgaa ataataacaa gaaatgttat acaaatacta tatctttttg acattaaaac
     2221 cacatgcatc ttccaaagct ccaaattaat gatgctgcag ctgcagcagg ggctacattc
     2281 ttgatcccca ctttaagtat tagttttgcg atttcagctg ctgc
//
LOCUS       DARYYD010000114         2304 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.115, whole genome shotgun sequence.
ACCESSION   DARYYD010000114 DARYYD010000000
VERSION     DARYYD010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2304)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2304)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2304
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.115"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(40..588)
                     /gene="raiA"
                     /locus_tag="TV188_001956"
     CDS             complement(40..588)
                     /gene="raiA"
                     /locus_tag="TV188_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEL1535266.1"
                     /translation="MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNL
                     KVYREKTAKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHRE
                     KMSTSQVFTSEFEAEKAEETPEIKVVRTKNVTLKPMDVEEARLQMELLGHDFFIYTDA
                     EDGATNVLYRREDGDLGLIEAK"
     gene            complement(664..1245)
                     /locus_tag="TV188_001957"
     CDS             complement(664..1245)
                     /locus_tag="TV188_001957"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEL1535267.1"
                     /translation="MCDACQRHFCRITQPTCSNCYQYRHEGACQDCIAWKRQGYQVDH
                     QSLYQYNTAMKDYFSRYKFQGDYVLRSLFAQELAKHIKKYYKAYTLVPVPVSKQRYDE
                     RGFNQVTAILEYANLAYLDLFERIDDTRQSSKTKKERLQLNNRYRLKKGAALPPKILL
                     IDDIYTTGSTIMSLRQELVRHGCQDIKSLSIAR"
     gene            complement(1473..1658)
                     /locus_tag="TV188_001958"
     CDS             complement(1473..1658)
                     /locus_tag="TV188_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002988813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Paratox"
                     /protein_id="HEL1535268.1"
                     /translation="MLTYEEFKQAIDHGYITGDVVMIVRKNGQIFDYVLPGEEVQPWE
                     VVTVEAVADILNELQII"
     gene            complement(1780..>2304)
                     /gene="spel"
                     /locus_tag="TV188_001959"
     CDS             complement(1780..>2304)
                     /gene="spel"
                     /locus_tag="TV188_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeL"
                     /protein_id="HEL1535269.1"
                     /translation="QHKTKVWEFDDYNFIISSNLYPSVEGKFNVGDNVDVFGLALSAE
                     VFSKDQIHSINGGLVKVNERKGAGKTIYMNVFIDGHKKDETSKYKITFEKSPVTFQEV
                     DVRLRKSFMLNDEIKLYQYGSKVLSGNWEFHGSGENEEGADLFKYPDYRYNNLIDIDK
                     KSHIDVYLFTNKEN"
BASE COUNT          650 a          489 c          374 g          791 t
ORIGIN      
        1 gcaaaaaaac aagaggtgag atgcctcttg tttttcaaat tattttgctt cgataagtcc
       61 taagtcacca tcctcacgac gataaagaac atttgttgct ccgtcctcag catctgtata
      121 gatgaagaaa tcatgcccta gaagttccat ctgcaagcga gcttcctcaa cgtccattgg
      181 ctttagagtc acatttttcg tgcggaccac tttgatttct ggagtttctt cagctttttc
      241 tgcttcaaat tcactagtaa acacttgact agttgacatt ttttcacgat gctttttggc
      301 aatttttgtt ttattttttc taatttgacg ttcgatttta tcaacgacta aatcaataga
      361 accatacata tcctgtgaaa cgtcttctgc acgaagtgtc actgaaccaa gcggaatagt
      421 gacttcaacc tttgcagtct tttcacgata aacctttaaa ttaacacgcg catctatttc
      481 ttgctcttca acaaaatatt tttcaatctt agtaagcttt gattctacat aatcgcgaat
      541 agcctctgtc acttcgatgt tttctccacg aatactgaat ttaatcataa gagtacctct
      601 ttcttgcgtt taaaacgctt tctttagttc tactatagcc gttttcatga aaatttgcaa
      661 gttttatcgt gcaattgaga gacttttgat gtcctgacag ccatgcctga caagctcctg
      721 ccttagactc attatggtgc taccggttgt atagatatcg tcaattaata agattttcgg
      781 tggaagagct gctccctttt tgagtcgata gcggttattt agctgcaggc gttctttttt
      841 cgttttgctt gattgtctag tatcgtcgat tcgctcaaat aggtcaagat aggctaggtt
      901 ggcatattct aaaatagctg ttacttgatt aaagcccctt tcatcatacc tttgcttgct
      961 aacaggcaca ggaaccaaag tataggcttt ataatacttt ttaatgtgct tagctagctc
     1021 ctgcgcaaaa agactgcgta aaacataatc tccttgaaat ttgtaacggc tgaaataatc
     1081 cttcattgcg gtgttgtatt ggtaaaggct ctgatgatca acctgatagc cttgcctttt
     1141 ccaggcaata caatcctggc aggcgccctc atgacgatac tggtagcaat tagagcaggt
     1201 tggctgagta atcctacaaa aatgacgctg acaggcatca cacataagat ccttattagg
     1261 acttaacaac agaattgctg tgatagacaa gctatcttta ctatttattg tggcagagta
     1321 gacagttcat tttgataccc tttttgattc atgtccttta tctcccgcac tgccttgagc
     1381 atagcctggc taataccatc atgaaaaaat agcacctgtc cttcaggtct ttccaaagag
     1441 cgcccaacgc gacctgaaat ttgaattagc ggtcaaataa tttgtaattc gtttaaaata
     1501 tcagcaactg cctcgactgt caccacttcc caaggctgca cttcctcccc tggcaacaca
     1561 taatcaaata tctgtccgtt tttacgcacg atcatgacca cgtctcctgt gatatatcca
     1621 tgatcaatag cttgcttaaa ttcctcgtat gttagcataa attacctcct tatcttatta
     1681 ttcgtaaaaa tctggtattg gtatattgga cacatttata tgtaccgaac aaaaaaacgc
     1741 cctcaattaa gagggtattc cttggtttct tgatactaac taattttctt tgtttgtgaa
     1801 tagatagaca tcaatatgac tctttttgtc tatatctatc aaattattat atctataatc
     1861 tgggtattta aataagtcag caccttcctc gttctcgcct gagccgtgaa attcccagtt
     1921 tccagataga actttggaac catactgata aagttttatt tcatcgttca gcataaatga
     1981 ttttctcaat ctaacatcaa cctcctggaa ggtaacggga gatttttcaa aagttatttt
     2041 atatttcgag gtctcatctt tcttatgccc atcaataaaa acgttcatgt aaatcgtttt
     2101 tccagctcct tttctctcat taactttaac gagaccacca ttgattgaat gtatttgatc
     2161 ttttgaaaat acttcagccg ataatgcaag accaaaaaca tcgacattat ctccaacatt
     2221 aaatttacct tctacagatg ggtataggtt acttgatatt ataaaattat aatcatcaaa
     2281 ttcccatact ttagttttat gctg
//
LOCUS       DARYYD010000115         2299 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.116, whole genome shotgun sequence.
ACCESSION   DARYYD010000115 DARYYD010000000
VERSION     DARYYD010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2299
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.116"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            47..403
                     /locus_tag="TV188_001960"
     CDS             47..403
                     /locus_tag="TV188_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535270.1"
                     /translation="MEDTYMTQACKKFMVSTMAALALAGVCLTASTHISKADDYVYGD
                     VEYLLTPKQEGYDDLVSFLESLGLNHFDATLYSDSMADQDYKKLLADFKGKTRSEVIS
                     AVLSELAKFYNDYSPF"
     gene            927..1976
                     /locus_tag="TV188_001961"
     CDS             927..1976
                     /locus_tag="TV188_001961"
                     /EC_number="3.4.22.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012515503.1"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="HEL1535271.1"
                     /translation="MKTIAYPNKPHSLSAGLLTAIAIFSLASSNITYADDYQRNATEA
                     YAKEVPHQITSVWTKGVTPLTPEQFRYNNEDVIHAPYLAHQGWYDITKAFDGKDNLLC
                     GAATAGNMLHWWFDQNKTEIEAYLSKHPEKQKIIFNNQELFDLKAAIDTKDSQTNSQL
                     FNYFRDKAFPNLSARQLGVMPDLVLDMFINGYYLNVFKTQSTDVNRPYQDKDKRGGIF
                     DAVFTRGDQTTLLTARHDLKNKGLNDISTIIKQELTEGRALALSHTYANVSISHVINL
                     WGADFNAEGNLEAIYVTDSDANASIGMKKYFVGINAHRHVAISAKKIEGENIGAQVLG
                     LFTLSSGKDIWQKLS"
BASE COUNT          770 a          448 c          402 g          679 t
ORIGIN      
        1 aaggaaaata tcacaaaaat aacgacggac aaaggaaccg ttggaaatgg aggacactta
       61 tatgacacaa gcttgtaaga aatttatggt ttctacaatg gctgccctag ctttggcagg
      121 agtctgccta acagcttcaa cccacatcag caaagctgat gactatgttt atggtgacgt
      181 ggaatatctt ttgacgccta agcaagaagg atacgatgat ttggtgtcat tcttggagag
      241 tctaggcctt aaccattttg atgccactct ttattcggac tctatggctg atcaagatta
      301 caaaaagcta ctagctgact ttaagggtaa aactcgtagt gaagttattt ctgcagttct
      361 atctgaatta gctaaatttt ataacgacta ttcccctttt taatgaaata acccaataag
      421 ttatcataga tcaaaactgc tcagacaacc ttccgagcgg ttttaacttg atagagctat
      481 gcttctcttt gtcaatctgc ttagtaacca gaccatctcc taaatcgtcc gcctagctaa
      541 tcaagtaata actgcaccat tgtccttact atcctagcta atgccctgat ttgctgacta
      601 agcttggcta agattgtgca agaatcccaa taacatcaaa gcctacacta gctcttatta
      661 gtggtctcaa taataacagc tcatgtctaa ggcatgacac caacaatacc aaacggtatc
      721 atcattggta aaataggtaa cgctaacata aaccaagctg aaatatccat tatagagatc
      781 cagtctgcca gcatctctac tatctcatca ctatttacta ataaataaag cttatcaaaa
      841 gcattgtctc aacaaaatat tgtgataata tataaatgtc attaacatta tttaatgata
      901 atatcaccat aacaagaaag ggttatatga aaacaatagc ttatccaaat aaacctcact
      961 ccttatcagc tggtctctta actgctatag ctatttttag cctggcgagt tcaaacatta
     1021 cttatgctga cgattaccaa aggaatgcta cggaagctta tgccaaagaa gtaccacatc
     1081 agatcacttc tgtatggacc aaaggtgtta caccactaac acccgagcag tttcgatata
     1141 ataacgaaga tgtgatccat gcgccatatc ttgctcatca aggctggtac gatatcacca
     1201 aggccttcga tgggaaggat aatctcttgt gtggcgcagc aacggcaggt aatatgctgc
     1261 attggtggtt tgatcaaaat aaaacagaga ttgaagccta tttaagtaaa caccctgaaa
     1321 agcaaaaaat catttttaac aaccaagagc tatttgattt gaaagctgct atcgatacca
     1381 aggacagtca aaccaatagt cagcttttta attattttag agataaagcc tttccaaatc
     1441 tatcagcacg tcaactcggg gttatgcctg atcttgttct agacatgttt atcaatggtt
     1501 actacttaaa tgtgtttaaa acacagtcta ctgatgtcaa tcgaccttat caggacaagg
     1561 acaaacgagg tggtattttc gatgctgttt tcaccagagg agatcagaca acgctcttga
     1621 cagctcgtca tgatttaaaa aataaaggac taaatgacat cagcaccatt atcaagcaag
     1681 aactgactga aggaagagcc cttgctttat cacataccta cgccaatgtt agcattagcc
     1741 atgtgattaa cttgtgggga gctgatttta atgctgaagg aaaccttgag gccatctatg
     1801 tcacagactc agatgctaat gcgtctattg gtatgaaaaa atattttgtc ggcattaatg
     1861 ctcatagaca tgtcgccatt tctgccaaga aaatagaagg agaaaacatt ggcgctcaag
     1921 tattaggctt atttacgctt tccagtggca aggacatatg gcagaaactg agctaaccag
     1981 tcatcattag gaacagacca agtgcttatt ggtctgtttt ttcgtctaac aatagcccta
     2041 ttagctcact gtcattggtt aaagcttgtc atgaactctt taagctcttg ttttgttaaa
     2101 cattaatgtg cctgttgttc ttttctaaga taagtaaact agatacctga cataaaaaac
     2161 aaacgttatt atttatctta ataaaaaaat cattttttga acataaaata cgaatattat
     2221 actaaaaata aatccaaata gtttacaatt tatggttgtt ttcatataat tttcatgaaa
     2281 ggagggaaat atatgaaaa
//
LOCUS       DARYYD010000116         2217 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.117, whole genome shotgun sequence.
ACCESSION   DARYYD010000116 DARYYD010000000
VERSION     DARYYD010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2217
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.117"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(97..1722)
                     /gene="groL"
                     /locus_tag="TV188_001962"
     CDS             complement(97..1722)
                     /gene="groL"
                     /locus_tag="TV188_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880885.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEL1535272.1"
                     /translation="MAKDIKFSADARESMVRGVDILADTVKVTLGPKGRNVVLEKAFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPIGIRRGIEAATTTAVEALKAVAQPVSGKEAIAQVASVSSRSEKVGDYI
                     SEAMERVGNDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDNEKMVADLENPFI
                     LITDKKISNIQDILPLLEEVLKTSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAVLTGGTVITEDLGLELKDATMAALGQAAKVTVDKDNTVIVEGA
                     GSSEAISNRVSLIKSQLETTTSEFDREKLQERLAKLAGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALINVMDKVAALELDGDAATGRNIVLRALEEPVRQ
                     IAYNAGYEGSVIIDKLKNSAAGIGFNAATGEWVDMIATGIIDPVKVTRSALQNAASVA
                     GLILTTEAVVATKPEPAAPAMPQGMDPGMMGGF"
     gene            complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TV188_001963"
     CDS             complement(1790..2077)
                     /gene="groES"
                     /locus_tag="TV188_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012514806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEL1535273.1"
                     /translation="MLKPLGDRVVLKFEAEKEQTVGGFVLAASHKEATKVGTVVAVSE
                     TGIRTITGDIVPPSVAVGDKVLVEYGSGLEVKDGDQELVICREADILAVLA"
BASE COUNT          626 a          557 c          390 g          644 t
ORIGIN      
        1 agggataatc atatcacctt aacgtcaggg gagtctttat aagttatttt tatatcctat
       61 gacagacaca ctagtctatc ctaacaggcc ttcttgttag aagccaccca tcatgcctgg
      121 atccattcct tgcggcattg ctggtgcagc aggctctggc ttagtggcaa caacagcttc
      181 ggtggtcagg ataagacctg caacagaggc tgcattttga agtgctgaac gtgttacctt
      241 gactggatca atgatacctg tagcaatcat atcaacccat tcaccagttg ctgcattaaa
      301 accaatacca gcagcactat ttttcagctt atcaataatc actgaacctt catagccagc
      361 gttgtaagca atttgacgca caggctcttc aagcgcacga agcacgatat tgcgaccagt
      421 tgctgcatca ccatcaagct caagggctgc aaccttatcc atgacattga taagagcagt
      481 accaccacct gcaacgatgc cttcttcaac cgcagcgcgt gttgcattta gcgcatcctc
      541 aatacgaagc ttcatttctt ttagctcggt ttcagtagct gcacccacct tgataactgc
      601 aacaccacct gctaattttg ctaagcgctc ttgtaatttt tcacgatcaa attcagatgt
      661 ggttgtttct aattgtgatt tgatcaggct aacgcggttt gaaatagctt ctgagctgcc
      721 tgcaccttct acaatcactg tattatcctt gtcaacagtt actttagccg cttgtccgag
      781 ggcagccatt gtagcatcct tcaattcaag accaagatcc tcagtgatga ctgtaccacc
      841 agttaagaca gcaatgtctt caagcatcgc tttacgacga tctccaaagc caggcgcttt
      901 aaccgctaca acattgaagg taccacgaat tttattaagc actagggtcg gaagggcttc
      961 gccatcaaca tcatcagcaa tgatcaacaa tggacggcta gtcttaagca cctcctcaag
     1021 caatggaaga atgtcttgga tattagaaat tttcttatca gtaatcagga taaatgggtt
     1081 ttcaagatca gcaaccattt tttcattgtc agtgaccatg tattgtgaca aatagccgcg
     1141 gtcaaactgc attccctcaa caacctcaag ctctgtttcc ataccacgtg attcctcaat
     1201 agtaatcaca ccatcatttc ccacgcgctc catagcttca gaaatatagt caccaacctt
     1261 ttcagaacgt gatgacaccg aagctacttg agcaatagct tcttttccag atactggttg
     1321 agcaacagcc tttaaggcct cgacagctgt cgttgtcgct gcttcaatcc cacgacgaat
     1381 accaattggg ttagcacctg ctgttacatt tttaagccct tcacgcacaa tcgcttgggt
     1441 caaaacagta gctgttgttg tcccgtcacc agcaatatca tttgtttttg aagctacctc
     1501 tgatacaagc ttagccccca tattttcaaa atgatcttct aattcaatct ctttggcaat
     1561 cgttacacca tcatttgtga tcaaaggaga accaaaggcc ttttcaagga ctacattacg
     1621 ccctttaggg ccaagggtta ccttaacggt atccgccaaa atatcaacac cacgtaccat
     1681 gctttcacga gcatctgctg aaaattttat atcttttgcc atgttatttc ctctattcct
     1741 atttgaatgt atatctgtta atcctacctg aaatgatagg gattcacaat taagctaaaa
     1801 ctgcaagaat gtcagcttca cgacagatga caagctcttg atcgccatct ttaacctcta
     1861 agcctgatcc atattcaacc aaaaccttgt cacctacagc cacacttggt ggaacaatgt
     1921 ctccagtaat agtacgaata cctgtctcac taacagctac aactgtccct actttagtgg
     1981 cttctttgtg actagcagca agaacaaagc caccgacggt ctgctctttt tctgcttcaa
     2041 attttaggac cacacgatct cctaacggtt ttaacatgaa tagtacctcc aataatgact
     2101 agattatcta ttttgttagc actcttgttt tatgagtgct aactttcttc tctattttat
     2161 cacttggtca aaaatagtca agaaaaaaag tctaggaaaa aagaaaagac ccagctg
//
LOCUS       DARYYD010000117         2001 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.118, whole genome shotgun sequence.
ACCESSION   DARYYD010000117 DARYYD010000000
VERSION     DARYYD010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2001
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.118"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..902)
                     /locus_tag="TV188_001964"
     CDS             complement(<1..902)
                     /locus_tag="TV188_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004819958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEL1535274.1"
                     /translation="MSKLEEAKNILNELKVPPKQQSDLCGYVILAMADIKKNDEWANA
                     TNKWIRIHDVIAFIREFYEVSYAENSRETFRKQAMHHFRNAAFIEDNGKATNSPNYRY
                     RLTDEMLLLVKTFQSSLWEEQKNNFLKSHQNLIDLYSSKKAVRKMPVKINGDDFTFSP
                     GKHNQLQKFIIEEFAPRFAENSECLYVGDTIQKDLVKNEEKLKELGFEITLHDKMPDV
                     VLYSEDKNWIYFVESVTSVGAMEPKRIKEIEEMTENVSAGKIYVTAFLDFKTFKKFSE
                     SLAWETEVWIADMPDHMIHLNGDK"
     gene            complement(895..>2001)
                     /locus_tag="TV188_001965"
     CDS             complement(895..>2001)
                     /locus_tag="TV188_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Eco57I restriction-modification methylase
                     domain-containing protein"
                     /protein_id="HEL1535275.1"
                     /translation="NMLGVSTKPEKYDVIIGNPPYLKVGKMANEALSMPDICYGSPNL
                     YFLFMEMASFNLVDNGELVFIVPRSWTSGAYFKKFREKFLNEVVLKHIHLFVSRDKVF
                     DKESVLQETMIIKAKKELNKLKNITITTTNDNFDFGSKTVFEASYDMVVSGEHKYVFL
                     ITDKEEADTIKKVNEWNDTLPTLGLKMKTGLTVDFRNQEALRNDAEEKAVPLFYSQHI
                     KDGKVIFPVGKENEYLLTEKKGLLQENTNYLFVKRFTAKEEKRRLQCGIYLAKKFPTY
                     KAISTQNKINFITGLQGLSDCLVYGLYVVLNSTLYDNYYRILNGSTQVNATEINSMPI
                     PPLTCIEDMGKELIKLKDMSEENCDEILGRFIYV"
BASE COUNT          628 a          401 c          237 g          735 t
ORIGIN      
        1 aatttatcac catttaaatg aatcatatgg tcaggcatat ccgcaatcca tacttccgtt
       61 tcccaagcta aagactctga gaatttttta aatgttttaa agtctaaaaa tgctgttaca
      121 tatattttcc cagctgaaac attttccgtc atttcttcaa tttcttttat tcgctttggc
      181 tccattgcac ccacagaagt tacagactca acaaagtaga tccagttctt atcttctgaa
      241 tataaaacaa catccggcat tttatcatgg agtgttatct caaagccgag ttcttttagt
      301 ttctcctcat tcttcaccaa atccttttga attgtgtcac caacatacaa acattcagag
      361 ttctcagcga atcgtggagc aaattcttca ataataaatt tctgtaattg attgtgtttg
      421 ccgggagaaa atgtaaaatc atctccgttt attttaacag gcatttttct taccgccttt
      481 ttagagctat atagatcaat taagttctga tgagatttta agaaattatt cttctgttct
      541 tcccacagac ttgattgaaa tgtttttact aataacaaca tttcatcagt taatcgatac
      601 ctgtaattag ggctatttgt tgctttccca ttatcttcaa taaatgctgc attcctaaaa
      661 tgatgcattg cctgtttacg gaatgtttct ctactattct ctgcatatga aacctcataa
      721 aactctctaa taaaggcaat aacatcatga attcttatcc atttattagt tgcattagcc
      781 cattcatcat tctttttaat atctgccatt gccaaaataa catatccaca tagatccgac
      841 tgctgttttg gtggaacttt caactcattc aaaatattct ttgcttcttc taatttagac
      901 atatataaat ctccctaata tttcatcaca attttcttca gacatatcct ttaatttaat
      961 cagttccttt cccatatcct caatacaagt tagtggtgga attggcatcg agttaatttc
     1021 agtagcatta acttgagttg atccatttaa aattctgtaa taattatcat aaagcgtaga
     1081 gttcaataca acatacaaac cataaaccaa acaatctgat aatccttgta agcctgtaat
     1141 aaaatttatc ttattctgtg tgctaattgc cttatatgtt ggaaattttt tagctaaata
     1201 aattccacat tgtaatctac gcttttcttc ctttgccgta aatcttttca caaataaata
     1261 attagtgttc tcctgcaata atcctttttt ctccgttaat agatactcat tttcttttcc
     1321 aacaggaaaa atcactttac catcttttat atgttgcgaa taaaataaag gaactgcttt
     1381 ttcctctgca tcatttctta aagcctcttg atttctaaaa tcaactgtca aaccagtttt
     1441 cattttcaag ccaagagttg gcaaggtatc attccattca tttacctttt taatcgtatc
     1501 agcttcttct ttatcagtta tcaaaaaaac atatttgtgt tctccggaaa caaccatatc
     1561 gtaagaagct tcaaaaacag tcttgctgcc gaaatcaaaa ttatcattcg ttgtagttat
     1621 agtaatgttt tttaacttat ttaattcttt cttggcttta ataatcatag tttcttgcaa
     1681 aacagactct ttatcaaaga ctttgtctct gcttacaaat aaatgaatgt gcttcaaaac
     1741 cacttcattt aaaaacttct cacgaaactt tttaaagtac gctccagaag tccatgatct
     1801 tggaacgata aacaccaatt cgccattatc aaccaaattg aaacttgcca tctccataaa
     1861 aagaaaatat aaattcggtg atccataaca aatatcaggc atggataaag cttcattagc
     1921 catttttcca acctttaaat aaggtggatt tcctataatt acatcgtatt tttcaggttt
     1981 agtactcacc cccaacatat t
//
LOCUS       DARYYD010000118         1908 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.119, whole genome shotgun sequence.
ACCESSION   DARYYD010000118 DARYYD010000000
VERSION     DARYYD010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1908
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.119"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            38..343
                     /locus_tag="TV188_001966"
     CDS             38..343
                     /locus_tag="TV188_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535276.1"
                     /translation="MLAVSTLSFGSAATARVVSAATAHPAPYPIIDEWNYGVSDNYGY
                     SNDYVKSPNNIGSKSSVTNLWGTVKDRDSQKYGWANSSATKSWNDVRLNTHWNYFTF"
     gene            410..>1908
                     /locus_tag="TV188_001967"
     CDS             410..>1908
                     /locus_tag="TV188_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEL1535277.1"
                     /translation="MKLKLCIVGFFFCLIAAIGLVSINDTQKPIPLPIDGAFSIQGKS
                     NLSNEEVYQTISDLSKEKKVTIYKPVVQNSGQLTYIKFDNTNHEQLKSAPITGMYYTL
                     GKLDSNSLKPLTSTGLQVIYLAYPWQIGGMIQFTGPLRLLLMISIYLTLLVVLFVVRA
                     RQIKEGVIRRSLGLPVHDLRRDYFMSFTFELVMAALLMISYSSFLGSGFFTYSSKLFF
                     SMLLTNLIIFQIIDIITFVLFWLTIKVEKPIEIIKNKAKNSLIFIVWLAVISIIIVVS
                     GVFLRETKASQSKINMQIKHLKPWSAVKDWKRPEFLGIENESVTNGEEANDSGAKYVE
                     IAKALKKLDFIYIKSSSAYVPEYMAASDVTEDFSKQLKSDGITHPEVNKELVYINQTG
                     AKVQNKVNGTNYQSLDNKIATIYIPHKFKENKASIENTVVAEQFTGTNYTKDDLTVQV
                     IPDGQEFFYFNENGSSVPENKDNLPLESVTDSKDNIVVVLDTDKMIENN"
BASE COUNT          667 a          277 c          350 g          614 t
ORIGIN      
        1 agaactaata tgaaaaattg gtgacaaaac attagttttg cttgctgtaa gcactttaag
       61 ttttggatct gctgctacag ctagagttgt tagtgcagca acagcgcatc cagctccata
      121 tccaattatt gatgaatgga attatggtgt aagtgataac tatggttatt ctaatgacta
      181 tgttaagtct ccaaataata ttggttcaaa atcttcagta actaatctat ggggaacagt
      241 taaggataga gattctcaaa aatatggatg ggcaaactca agcgcaacaa aaagctggaa
      301 tgatgttcga ttaaatacac attggaatta ctttacattt taaaaatggt ttatgaaagc
      361 taaaggccca ataatgctat agggcctttt atgatatagg taggtgctta tgaaattaaa
      421 attatgcatt gttggattct tcttttgttt aattgctgcc attggtctgg ttagtattaa
      481 tgatactcaa aaaccaatac ctttaccaat tgatggtgcc ttctccattc aagggaaaag
      541 caatctttct aatgaagaag tgtatcaaac gattagtgac ctatcaaaag agaaaaaagt
      601 taccatttac aaaccggtag ttcaaaattc ggggcagttg acttatatca agtttgataa
      661 tactaatcat gaacaattaa agtctgcacc aatcacaggg atgtattata ccctagggaa
      721 attagattca aatagtttaa aaccgctcac atctacaggt cttcaagtca tatatctggc
      781 ttacccttgg cagatagggg gaatgataca atttactggt ccgttgagat tattgctaat
      841 gatttcaatt tacttaacct tattagttgt tctatttgtt gttagagcga gacagattaa
      901 agaaggagtg ataagacgtt ctttaggatt acctgtacac gacctaagaa gagattattt
      961 catgtcattt acttttgaac tggttatggc cgctttattg atgatttctt atagttcttt
     1021 tttgggtagt ggttttttca cctacagttc caagttattt ttttctatgc ttttaactaa
     1081 tttgatcata tttcaaatca ttgacatcat cacctttgtt ctattttggc taactattaa
     1141 ggttgaaaaa cctattgaaa ttataaaaaa taaggccaaa aatagcctca tttttatcgt
     1201 atggcttgcg gttatttcta tcataatagt tgtttcagga gtctttttac gggaaacaaa
     1261 ggctagtcaa tcaaagataa acatgcagat aaagcattta aaaccatgga gtgcagtaaa
     1321 agattggaaa agaccagagt ttttgggtat tgaaaatgaa tctgttacta atggagaaga
     1381 agcaaatgac tcaggagcta agtacgtaga gattgctaaa gccttaaaaa aactggattt
     1441 tatatatatc aaatcatctt cagcctatgt tccagaatat atggcagctt ctgatgttac
     1501 agaagatttt tctaagcaat taaaaagtga tggaataacg catccagaag ttaataagga
     1561 actggtttat attaatcaaa caggtgctaa ggtacaaaat aaagttaatg gaacgaacta
     1621 tcaatcatta gataataaaa tagcaaccat ctatattcct cataaattta aagagaataa
     1681 ggcatcaatc gagaatacag ttgtagcaga acaatttact ggtacaaact atacaaaaga
     1741 tgaccttacg gtgcaagtca ttcctgatgg gcaagaattt ttctatttca atgaaaatgg
     1801 tagtagtgtt cctgaaaata aagataatct acctttggaa agtgtgacag atagtaagga
     1861 taatatagtc gttgtgctag atactgataa aatgatagaa aataacga
//
LOCUS       DARYYD010000119         1881 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.120, whole genome shotgun sequence.
ACCESSION   DARYYD010000119 DARYYD010000000
VERSION     DARYYD010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1881
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.120"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            18..1097
                     /locus_tag="TV188_001968"
     CDS             18..1097
                     /locus_tag="TV188_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012516462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEL1535278.1"
                     /translation="MSNCGDSIYTLVLSWYVLETTNSTWYVGLLNFLIFIPNTFSFIF
                     GKKIDSYPKKNLLVILEWAQLLAVLGIILGMSLREIHASLSLTIIFSCVFLASMVGLN
                     TYTVQDALVPKLIPTKDLAKAEMYMSVAYNGTDYVFTAISGFLLSVISYIPLLFINIV
                     TFLGSILFFRRIAFKEIIEQTNERTDFLSGLRFIWHNKVVLAITLGGAIANFLFASLN
                     VYQLLIAREVGNSAFYGLLVSVSAIGTLVGTTFVANLVLQKLSVGKAFWLATTLLGTG
                     IGLTALVPNRFGLLLLWFLSCLFLGITHVTQKPILRTEIPDEHLGEVFSAFYTVTIPT
                     LALGSLILISLLYFSNKMLRQYDIC"
     gene            complement(1441..1524)
                     /locus_tag="TV188_001969"
     tRNA            complement(1441..1524)
                     /locus_tag="TV188_001969"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1488..1490),aa:Leu,seq:caa)
     gene            complement(1543..1614)
                     /locus_tag="TV188_001970"
     tRNA            complement(1543..1614)
                     /locus_tag="TV188_001970"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1580..1582),aa:Gln,seq:ttg)
     gene            complement(1623..1695)
                     /locus_tag="TV188_001971"
     tRNA            complement(1623..1695)
                     /locus_tag="TV188_001971"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1660..1662),aa:His,seq:gtg)
     gene            complement(1707..1777)
                     /locus_tag="TV188_001972"
     tRNA            complement(1707..1777)
                     /locus_tag="TV188_001972"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1743..1745),aa:Trp,seq:cca)
     gene            complement(1784..1864)
                     /locus_tag="TV188_001973"
     tRNA            complement(1784..1864)
                     /locus_tag="TV188_001973"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1828..1830),aa:Tyr,seq:gta)
BASE COUNT          534 a          406 c          361 g          580 t
ORIGIN      
        1 tatttctggg gcgactgatt agcaattgcg gtgactcgat ttatacccta gtgctgtcct
       61 ggtatgtact agaaaccact aatagtactt ggtatgttgg attattgaac tttctcattt
      121 ttattccaaa caccttctcc tttatctttg gaaaaaagat tgattcgtac cctaagaaga
      181 acctgctagt gattctggag tgggcccaat tattggctgt cttaggtatt attttaggaa
      241 tgtccttaag agagatacac gcaagtctta gcttaaccat tatttttagt tgtgtttttc
      301 tggcttctat ggttgggttg aatacctata ctgttcaaga tgctcttgta cctaaactca
      361 ttcctactaa agatctagct aaagcagaaa tgtatatgtc agtggcttat aatggaacag
      421 attatgtttt tactgccatc agtggctttt tgctttctgt gatcagctac attcctttgc
      481 ttttcattaa tatcgttacc ttcttaggtt caatcctatt ttttagaaga atagcattta
      541 aagaaataat tgaacaaaca aatgaacgaa cagacttttt aagtggcttg cgctttatct
      601 ggcacaataa agtggtgtta gccatcacat tgggaggtgc tatcgctaat ttcctttttg
      661 ccagcttaaa tgtctatcag ttattaatag caagagaggt agggaattca gctttttatg
      721 gcctcttagt atctgtaagt gctatcggaa ccctggtagg aacaaccttt gttgctaacc
      781 ttgtcttgca aaagttaagt gtaggaaaag ctttttggct agcaactacc cttttgggca
      841 ccggtattgg ccttacagca ttagtcccca accgttttgg tttgttgctt ctttggtttc
      901 tttcctgtct atttctcgga ataacgcatg ttacccaaaa acctatttta cgaactgaga
      961 ttcctgatga gcatcttggt gaagttttca gtgcttttta taccgtaacc atcccaacac
     1021 ttgccttggg ttcgcttatc ttaattagtc tgctttattt ctcaaacaag atgctaagac
     1081 aatacgatat ttgctaaagc gtcattaacc agagaacaca tgataactga tattgcgaca
     1141 ttaatcaaaa ccaaacgtaa agaaaaagct cacccacaaa gaattggcta aaagtcctag
     1201 tatccaaagc tcacatcaca catgccttgg agcaacctta ttccaaattc aaacgctaag
     1261 ctgcacgcca ctaacaggtg atcaaagaca tcaagcgcaa tgctttggat ttaggagctt
     1321 tgaagccaag attctcatta cctttaacat ctagagagga ccaatctgat cctctgacat
     1381 caagtcataa aacaaaaaaa caaggtttac aaaccttgtt ttttcaatat ttttaaacta
     1441 taccggcggc cggggtcgaa ccggcacgtc cttgcggaca ctggattttg agtccagcgc
     1501 gtctgccaat tccgccacgc cggctttaag tataaaacta aactggggta gctggattcg
     1561 aaccaacgca tgagggagtc aaagtccctt gccttaccgc ttggctatac cccaataaaa
     1621 taggcgagtg atgggaatcg aacccacgaa tgtcagagcc acaatctgat gtgttaacca
     1681 cttcaccaca cccgccatat tctgaacacg ggcagtagga atcgaaccca cactgaaggt
     1741 tttggagacc ttagttctac ctttaaacta tgcccgttca ggatggaaag agagggattc
     1801 gaacccccga acccgaagga gcggatttac agtccgccgc gtttagcctc ttcgctatct
     1861 ttccaaaaca tattaaatta c
//
LOCUS       DARYYD010000120         1715 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.121, whole genome shotgun sequence.
ACCESSION   DARYYD010000120 DARYYD010000000
VERSION     DARYYD010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1715
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.121"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(311..604)
                     /locus_tag="TV188_001974"
     CDS             complement(311..604)
                     /locus_tag="TV188_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEL1535279.1"
                     /translation="MNERDLVQLIEQTLKDEEVQNNVTYRNLLEESLQQLSLKKPVYL
                     VSTRLAGHISTYLMTNHYEAPKAIIVLAQSIASTPAKHRGLISIPFWLSNIFR"
     gene            complement(634..855)
                     /locus_tag="TV188_001975"
     CDS             complement(634..855)
                     /locus_tag="TV188_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009568291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEL1535280.1"
                     /translation="MDTKFTALTEEQLKSVEGGKNGVVKLPGGTGVYCWNTGKNSAKC
                     GMDWSVAGPYVGKIIVNGWVNHGPWASRP"
     gene            1070..1540
                     /locus_tag="TV188_001976"
                     /pseudo
     CDS             1070..1540
                     /locus_tag="TV188_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT          556 a          313 c          273 g          573 t
ORIGIN      
        1 acgataagat cattccaata gcgtagcaca tgacaacaac attaaggtaa aaataaatca
       61 ttatttgtaa tgtacttgac aaaatctcct ttataagaat gattgtaact aaaattggaa
      121 tcaaaattgt acttttaaaa tatagccaaa attgttttgc aatttgagag attgaaagaa
      181 cttcctttga ctgtttatag actaatgtaa aagttaggag ttcaagcaaa aaactccaaa
      241 aaatgtgtct tattttatga gtgcattgcc aatctacaac tccttctaaa tcctgatctg
      301 aaaatatttt ttaacgaaat atattactta accagaatgg tatagaaatt aaacctctat
      361 gtttagctgg ggttgatgcg atagattgag caagaactat aatcgctttt ggtgcctcat
      421 aatgatttgt cattagatag gttgaaatat gtcctgctaa cctggtacta actaaataca
      481 caggcttttt gagtgataat tgctggagac tttcttccaa aagattccta taagtgacat
      541 tattttgcac ctcttcatct tttagagtct gttctatcag ctgtactaaa tctctttcat
      601 tcatgatttc acacctctct atataaatta aaattatgga cgacttgccc aaggtccatg
      661 gttaacccaa ccattgacaa ttatcttacc aacatatggt cctgccacac tccagtccat
      721 accacatttt gcactatttt ttcctgtatt ccaacaatat acaccggtcc ctccaggtaa
      781 ttttacaact ccattttttc caccctcaac tgatttcaat tgctcttcag tcaacgctgt
      841 aaattttgta tccatgacga atacctcctt tatatgtgtt tttattttgt ccggttgcaa
      901 gcttgacaga cttagtataa cactttcggt taaaatttgt tctccatttc ctaaacagtc
      961 atcgaaacgt cctaaatggg aaaaatttac cgcttaagac ttaaattcaa ccgtttgaga
     1021 taatttgata gatttgtcag attaccattt aggacgtttc gataaccaat atctgcctca
     1081 acaagcttat atttttagtg gatcaatttt agaaaatctt actctcggtg caaaccaagc
     1141 gattactcaa gaggatatta tcaatgcctg tgatatggca gaaattagag aagatattga
     1201 acaaatgcct atgggctatc agacagaact atctgatggg gcaggatttt ctggtggaca
     1261 aaaacagaga attgcattag ctagagcatt attaaccaag tctcctattc taattctcga
     1321 tgaggcgaca agcggactag atgtcttaac ggagaaaaaa gtgattgata acctaatgtc
     1381 aatgaccgag aaaacgatta ttttcgttgc ccatcgtctt agtactgctg aacgtactag
     1441 ccaaattgtt gtacttgata aaggaaaaat aatcgagata ggttcgcata acgaattaat
     1501 gacgcatcaa ggcttctatc atcatttatt tagtaagtaa ggagatattc atgaatccaa
     1561 atctgtttag aagtgctgaa ttttatcagc gacgctatca taattttgcg ataattctta
     1621 ttataccatt aacattattc gtcatatttt tactttcatt ttcttttctt ggtcaaaaag
     1681 aagtaacggt atcgtcacga ggtgaaatta tgcct
//
LOCUS       DARYYD010000121         1695 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.122, whole genome shotgun sequence.
ACCESSION   DARYYD010000121 DARYYD010000000
VERSION     DARYYD010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1695
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.122"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..221
                     /locus_tag="TV188_001977"
     CDS             <1..221
                     /locus_tag="TV188_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1535281.1"
                     /translation="NAKLADVTKVTELNDFLDELANEPIVIKGHEYSKRFIDFLEYLA
                     ESEDEFTSEEIVLIDNVLEQYEANKKGE"
     gene            225..836
                     /locus_tag="TV188_001978"
     CDS             225..836
                     /locus_tag="TV188_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1535282.1"
                     /translation="MRNWKIIGKYPQPNALGVIEGTHVIITGDDGASIPQTIKKDLSS
                     TNDFEVIKMVLDEFKKSEYVEIAMGEAVQKVDDLEKLSQETAKTATTAQTAAGLARAA
                     AERTQKMINLQTIHVLTTSDKVEPDIYKGMLELIAPAKKGQYQEHDVFTVLDDKHEDL
                     AGEGNLVFVYVNEPFEYDKQTLKDLESEDKVTVIKYADLVKQD"
     gene            847..1137
                     /locus_tag="TV188_001979"
     CDS             847..1137
                     /locus_tag="TV188_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535283.1"
                     /translation="MIDFVQIGAFCGAALSILGVWGFIVNPFKKAMEANELAMAQLKD
                     SIKELAYELKNLDRDREITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            1140..1319
                     /locus_tag="TV188_001980"
     CDS             1140..1319
                     /locus_tag="TV188_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535284.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVTSTVIM
                     SGIVCVLMNVSDIKE"
     gene            1431..>1695
                     /locus_tag="TV188_001981"
     CDS             1431..>1695
                     /locus_tag="TV188_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1535285.1"
                     /translation="MTFLDKIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPYNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWEESI"
BASE COUNT          559 a          313 c          398 g          425 t
ORIGIN      
        1 gcaacgctaa attagctgat gtcacaaaag taactgagct taacgacttt ttagacgagt
       61 tagccaacga gcctatcgtc atcaaaggcc atgagtactc taagcgattt atcgattttt
      121 tggaatactt ggcagaatcg gaagacgaat ttacatcaga agaaatcgtc ttaatcgata
      181 atgtcttaga gcaatacgaa gcaaacaaaa aaggagagta aattatgcgc aattggaaaa
      241 tcatcggcaa atatccacaa ccaaacgcgc taggggttat tgagggtaca catgtcatca
      301 tcacaggtga tgacggtgca tctatcccgc aaacgataaa aaaagatctg tcatctacaa
      361 atgattttga ggtcattaaa atggtcctcg acgagtttaa aaaatcagag tatgtcgaaa
      421 tcgcaatggg cgaggcagtc caaaaagtgg acgacttgga aaaactatcg caagaaactg
      481 ctaagacagc aacaactgca caaacagccg ctggtttggc cagggcagct gcagagcgca
      541 cacaaaagat gattaacttg cagactatcc acgttttgac aaccagcgat aaagtcgagc
      601 ctgacatcta caaaggcatg cttgagctta ttgcgccggc caaaaaaggg caatatcaag
      661 agcatgatgt ctttacggtg ctagacgaca agcatgagga tcttgcaggc gagggcaatc
      721 tcgtctttgt gtatgtcaac gagccgtttg agtatgacaa acaaacgctc aaagacttgg
      781 agtctgagga caaagtcaca gtcattaaat atgcggattt ggtaaaacaa gattagaggt
      841 ggttagatga tagattttgt acaaattggt gctttttgtg gcgctgcttt gtctatcttg
      901 ggtgtttggg gatttatcgt caatcccttt aaaaaagcca tggaagctaa cgagctagcc
      961 atggcccaac tcaaagactc gatcaaggag ttagcctacg agctaaaaaa tcttgatcgc
     1021 gatagggaga taaccaaaaa gattatcgat cggcatgagg agcgtttagg acgtgtagag
     1081 gacgacatta ttgtcaataa agagcaaatc aaaacattat ttaaaaaagg agactaaaaa
     1141 tggataaatg gtttaaaaaa gtagcaatca aaacaattaa gacaatggcc caaaccgctg
     1201 taggggttat tggatcaagc gcattgatta ctgacgtcaa ctggcaggtg gtgacctcaa
     1261 cagttattat gtcaggtatt gtctgcgtct tgatgaatgt gtctgacatc aaggaatagc
     1321 attatgcgag caatcacacg attagcaata gtcatagcaa tcacaatact gtatttaccg
     1381 ctatctgtga ttgctctgat tgtttatccg tttttagata aggaggacag atgacctttt
     1441 tagataagat taagcaaggc tgcttagatg gctggaccaa gtacaaaatc ttgccatctt
     1501 taacagcagc acaggcaatc cttgagagcg gttggggtaa gtatgcccca tataacgctc
     1561 tatttggtat caaggcagat agctcttgga cgggtaagtc atttaacaca aaaactcagg
     1621 aggagtatca gccgggtgtt gtaacggata ttgtagatcg ttttagggcc tatgatagct
     1681 gggaggaatc catcg
//
LOCUS       DARYYD010000122         1661 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.123, whole genome shotgun sequence.
ACCESSION   DARYYD010000122 DARYYD010000000
VERSION     DARYYD010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1661
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.123"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..774
                     /locus_tag="TV188_001982"
     CDS             <1..774
                     /locus_tag="TV188_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="USG protein"
                     /protein_id="HEL1535286.1"
                     /translation="DEKNTRKHYCIMKRVQDADEDYEYKKARQELQIEDLNRYGIFTY
                     LVNKYDEITEILSTLVDRFRRKTIFISGSAYSYSAYSQKTGENFIHKLSFELSKNGYH
                     IVNGYGKGVGEFVLNGVADYCLTHKSKINDFLTLMPFPQNSSLGIDLDKLYKENREQM
                     IESCGIAIFLFGNKEAEDIASGVMDEYELSKKHGLVCLPIEYTGGASKEIYDQTTQEI
                     SDKNTISAIEQANKQCDGDIDMSVKNIVQAVKILNKEEF"
     gene            775..1272
                     /locus_tag="TV188_001983"
     CDS             775..1272
                     /locus_tag="TV188_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIR domain-containing protein"
                     /protein_id="HEL1535287.1"
                     /translation="MAKRQVFFSFHYDNDNWRAGQVRNMGKVDSSSTFSDNDWEEVKE
                     KTESKIKEWIDEQLNKRSCLVVLIGEKTANRKWINYEIRKAYELNKGIVGIYIHKLEN
                     SLGEQDDKGNNPFDYLTLEGEKLSKYVKCFDSNYSSSKYVYSDIKDNIEGLIEYGINH
                     KPSTW"
     gene            complement(1296..>1661)
                     /locus_tag="TV188_001984"
     CDS             complement(1296..>1661)
                     /locus_tag="TV188_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535288.1"
                     /translation="NLQDKIKAIDKEMQELSATMEQVHTVKKYRQYYKEYKASPSDKA
                     FFEEYKAQITLYENALSELKKSYSKLPNSKGILDRLDKLQEKKNTLMQEYSSSKSIMD
                     ELYKIRKNYGIYMGKEMER"
BASE COUNT          615 a          199 c          312 g          535 t
ORIGIN      
        1 gatgaaaaaa atacaagaaa acattattgt attatgaaaa gagtccaaga tgctgatgag
       61 gattatgaat acaaaaaagc aagacaggag ctacaaattg aagacctaaa tagatatggt
      121 atttttacat atttagtaaa taaatatgat gaaatcaccg aaatattgag cactcttgtc
      181 gatagattta gaaggaaaac aatatttata tctggtagtg cgtactccta ttcggcttat
      241 tctcagaaaa ctggcgaaaa ttttattcat aaactatctt ttgaactatc aaaaaatggt
      301 tatcatattg tgaatggata tggtaaagga gtcggtgaat ttgtattaaa tggagttgca
      361 gattattgtt tgactcacaa gtccaaaata aatgattttt taacacttat gccttttcct
      421 caaaatagtt cattaggtat tgatttagat aagctatata aagaaaatag agagcagatg
      481 attgaaagtt gtggtatagc tatatttctt tttggtaata aggaggcaga agatattgca
      541 agcggagtta tggacgaata tgagttatca aaaaagcatg gattagtatg tttgcctatt
      601 gaatatactg gcggtgcatc taaagaaata tatgatcaaa caactcaaga aatttcagat
      661 aaaaatacaa taagtgcaat tgaacaggca aataaacaat gcgatggcga tattgatatg
      721 tctgttaaaa acatagttca agcagttaaa atattaaata aggaggaatt ttaaatggca
      781 aaaagacagg tattttttag ctttcattac gacaatgata attggagggc aggacaggtt
      841 cgcaatatgg ggaaagtaga cagtagttct accttttctg ataatgactg ggaggaagta
      901 aaagaaaaaa ctgaaagtaa aattaaagaa tggattgatg aacagttaaa taagcgttca
      961 tgtttggttg ttttgattgg agaaaaaaca gcgaacagaa aatggataaa ttatgaaata
     1021 agaaaagcat atgagttaaa taaaggtatt gtgggaattt atattcacaa gttggagaat
     1081 tcactgggag agcaagatga taagggtaat aatccttttg attatttaac attagaaggt
     1141 gaaaaacttt caaagtatgt taaatgtttt gactccaact attcatcaag taaatatgtt
     1201 tatagcgata ttaaagataa tattgaaggt ttaattgagt atggaataaa ccataaacca
     1261 tcaacttggt aataaatgat gatggagaga aaaaattatc tctccatctc cttacccatg
     1321 taaattccat aattttttcg tatcttgtaa agttcgtcca taatagattt tgaggaagaa
     1381 tactcttgca taagggtatt ctttttttct tgcaatttat caagtctatc taaaataccc
     1441 ttagaatttg gcaacttgga atatgatttt ttaagctctg aaagggcatt ttcatataag
     1501 gtaatctgag ctttgtactc ttcaaaaaat gccttgtcag atggacttgc cttatattct
     1561 ttgtagtatt gcctgtattt tttaacagtg tgaacttgct ccatagtggc agaaagctcc
     1621 tgcatttcct tatcaatagc cttgatctta tcctgtaaat t
//
LOCUS       DARYYD010000123         1608 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.124, whole genome shotgun sequence.
ACCESSION   DARYYD010000123 DARYYD010000000
VERSION     DARYYD010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1608
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.124"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            91..648
                     /gene="efp"
                     /locus_tag="TV188_001985"
     CDS             91..648
                     /gene="efp"
                     /locus_tag="TV188_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEL1535289.1"
                     /translation="MIEASKLRAGMTFEAEGKLIRVLEASHHKPGKGNTIMRMKLRDV
                     RTGSTFDTTYRPDEKFEQAIIETVPAQYLYKMDETAYFMNTETYDQYEIPVANVEQEL
                     LYILENSDVKIQFYGTEVIGVQVPTTVELTVTETQPSIKGATVTGSGKPATLETGLVV
                     NVPDFIEVGQKLIINTAEGTYVSRA"
     gene            691..1080
                     /locus_tag="TV188_001986"
     CDS             691..1080
                     /locus_tag="TV188_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEL1535290.1"
                     /translation="MTTENIGEIVISPRVLEVITGIATMQVEGVHSLHNKNMADTFNK
                     ASLGKGVYLQTEENGTVNADIYVYLQYGVKVPAVSMAIQRAVKSAVYDMAEVTISYVN
                     IHVEGIVPEKTPKPEMKSLFDEDFLDD"
     gene            1073..1525
                     /gene="nusB"
                     /locus_tag="TV188_001987"
     CDS             1073..1525
                     /gene="nusB"
                     /locus_tag="TV188_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEL1535291.1"
                     /translation="MTKHFQHSRRDLRERAFQALFAMEMGGDFLPASQFAYDYDKEAA
                     DDKQPSELPVFLLNLVNGVMDHKAELDEVIKKNLKTSWSIERLTVVDKTMLRLGLFEM
                     TLFEETPDRVALNEIIEIAKKYSDDTSAKFINGLLSQFVSDESAAVTE"
BASE COUNT          483 a          289 c          375 g          461 t
ORIGIN      
        1 aagggctgat aatggtcata aaacatttga gcctacagct cttttgtggt aaaataagac
       61 gataactatt ttagtaagag gtaataacaa atgattgaag caagcaagct tagagcaggt
      121 atgacgtttg aagcagaagg aaagctaatt cgcgtacttg aagcaagcca tcataagcca
      181 ggtaagggaa acactatcat gcgtatgaaa ttgcgtgatg ttcgtactgg ctctacattc
      241 gacacaacct atcgtccaga cgaaaagttt gaacaggcta ttatcgaaac agtgccggct
      301 caataccttt acaagatgga cgagactgct tactttatga atactgaaac ctatgaccag
      361 tatgagattc cagtagccaa tgttgagcaa gagctattat atatccttga aaactctgat
      421 gtgaaaatcc agttttatgg aacagaggtg atcggagttc aggtaccgac tactgttgag
      481 ttgactgtta cagagaccca gccatcaatc aagggagcaa ctgttacagg ctctggtaag
      541 cctgcaaccc ttgaaacagg actcgtggta aacgttccag actttattga ggtaggacaa
      601 aagctaatca tcaatactgc tgaggggact tacgtttctc gcgcttaatt cgctttccgg
      661 aattagtcta agagaaagaa aggaaatgct atgacaactg aaaatatcgg tgaaattgtt
      721 atttcgccac gagttcttga ggttattacg ggaattgcta cgatgcaggt cgagggtgtt
      781 cactcgcttc acaataaaaa catggcagat acctttaata aagctagtct tggtaagggc
      841 gtctatcttc agacggaaga aaatggaaca gtcaatgcag acatctatgt ttacctgcaa
      901 tatggtgtaa aggttcctgc ggtgtcaatg gctattcaaa gggctgttaa gtcagctgtt
      961 tatgacatgg ctgaggttac catttcttat gttaatatcc atgttgaggg gattgttcct
     1021 gaaaagacac caaagccaga aatgaaatca ttgtttgatg aggatttttt ggatgactaa
     1081 gcattttcaa cattcgagaa gagatttgcg tgagcgtgct tttcaagctt tatttgctat
     1141 ggagatgggc ggagattttc tgcctgcctc acagtttgcc tatgactatg acaaggaagc
     1201 agctgatgac aagcagcctt ctgagcttcc tgtttttctg ttaaatcttg tcaatggcgt
     1261 tatggatcat aaggctgagc ttgatgaggt tatcaagaaa aaccttaaaa cgagctggtc
     1321 cattgagcgc ttgacagtgg tagacaagac gatgttgcgt cttgggctct ttgagatgac
     1381 cctgtttgag gagacacctg atcgtgtagc cttaaatgaa atcattgaaa ttgctaaaaa
     1441 atattctgat gatacctcag ctaagtttat taatggctta ctcagtcagt ttgtttctga
     1501 tgagtcagct gcagtgacag aataacaagc tggtgaaagc ttcttaagtt actaaagccc
     1561 tatagggctt tttgaatgct caaaaacgtc tcatctggtt ggctatgt
//
LOCUS       DARYYD010000124         1586 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.125, whole genome shotgun sequence.
ACCESSION   DARYYD010000124 DARYYD010000000
VERSION     DARYYD010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.125"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..>1586
                     /locus_tag="TV188_001988"
     CDS             <1..>1586
                     /locus_tag="TV188_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017643042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HEL1535292.1"
                     /translation="IVDGDLILCWDSVDELFPTGMLEDMMDSLYELIISLTQKEEWEK
                     KVDVLPEKQKSIRMQDVEGILPLQYPSETLYDGFLRNVKLNPDRVAIIDSETKEEITY
                     HKLYEISLKVADCLGKNGVKKGDYVGITLPRGSRQLYAIFGILFTGAAYVSIGIAQPN
                     DRRTKIYDQIGIKCIISDEKTVIDCKLNKNEVKIIDLDVAMANVAKLKQPVEISPYDS
                     AYIIMTSGTTGVPKGVEIMHTSAVNTCIDLNEKYNVNAEDTILMVSAIDFDLSVYDIF
                     GILHAGGTVITTSEDNYRNPDEWLNLVDEYKVTIWDSVPILFDMIVTMAEGKNRNLPF
                     RIVMLSGDWIAINLPERFYNISENINSIVVAMGGATEASIWSNHLNVPRKIPKDWISI
                     PYGRPLKNQVYRVVDEFGRICPNYVKGELLIGGVGVAKCYHGDEELTNKKYFEQDGMR
                     WYRTGDNGRTWNDGIIEFLGRKDTQVKVKGHRIELGEIENALIVFENIKKAIALIVKD
                     GNVNKLVGFAEIFDCKESNQ"
BASE COUNT          570 a          169 c          348 g          499 t
ORIGIN      
        1 tattgtagat ggagatttaa ttctttgctg ggatagcgtg gatgaacttt ttccaacagg
       61 aatgttagaa gacatgatgg attctttata tgaattgatc atatctttaa cacagaagga
      121 agaatgggaa aagaaagtag atgttttacc tgaaaagcaa aagtctatta gaatgcagga
      181 tgttgaggga attttaccac ttcaatatcc tagcgaaacg ttatatgacg gatttctcag
      241 aaatgtaaaa ctcaatccag atagagttgc gattatagat tctgaaacga aggaagagat
      301 aacatatcat aaactttatg aaatctcttt aaaagttgcg gattgtttag gtaaaaatgg
      361 tgttaaaaag ggagattatg taggaataac acttccaaga ggtagcagac aactttatgc
      421 tatttttggg attttattta ccggtgcagc atatgtatca attggtattg ctcagccaaa
      481 tgatagaaga actaaaattt atgatcaaat cggaataaag tgcattataa gtgatgaaaa
      541 gacagtgata gattgtaaat taaataaaaa tgaagttaaa attattgatt tggatgtagc
      601 tatggcaaat gtggctaaat taaagcaacc tgttgaaatt agcccttatg atagtgcgta
      661 tattattatg acgtctggaa caacaggtgt tcctaagggt gttgagatta tgcatacaag
      721 tgccgttaat acttgcattg atttaaatga aaaatacaat gtaaatgctg aagatacaat
      781 actgatggtg tcggcaatag actttgattt gtcggtttat gatatttttg gaatacttca
      841 tgctggagga acggttatta caacaagtga agataattat agaaatcctg atgaatggtt
      901 aaatttagtc gatgaatata aggttacaat atgggattct gtgccgattt tgtttgatat
      961 gattgttact atggctgaag gtaaaaatag aaacttacct tttagaattg tgatgctttc
     1021 aggggattgg attgctataa atttaccaga aagattctat aatattagtg aaaatataaa
     1081 ttctattgtt gtcgctatgg gtggagccac agaagcatct atttggtcaa accatttgaa
     1141 tgtaccaaga aaaataccga aagattggat ttccattcca tatggtagac ctttgaaaaa
     1201 tcaagtgtat agagttgtgg atgaatttgg taggatctgc cctaattatg ttaaaggtga
     1261 acttcttatc ggtggagttg gtgttgctaa atgttatcat ggtgacgaag aattaacgaa
     1321 taaaaagtac ttcgaacaag atgggatgag gtggtataga actggagata atggtagaac
     1381 atggaatgat gggattattg agtttcttgg aagaaaagat actcaggtaa aagttaaagg
     1441 acatagaata gaacttggag aaatagagaa tgctttaatt gtatttgaaa atataaaaaa
     1501 agcgatcgct ttaattgtta aagatggaaa tgttaataaa cttgtaggat ttgcggaaat
     1561 atttgattgc aaagaaagta atcaaa
//
LOCUS       DARYYD010000125         1579 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.126, whole genome shotgun sequence.
ACCESSION   DARYYD010000125 DARYYD010000000
VERSION     DARYYD010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1579
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.126"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            133..1269
                     /locus_tag="TV188_001989"
     CDS             133..1269
                     /locus_tag="TV188_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014636301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEL1535293.1"
                     /translation="MILEKNCNYIDDISRNNTFTVNPKMTYQFGHAFYLDSDLNYWNK
                     QWDMQRSISTSSRFWHKSSGEVTIGVIDSGITDNNTDISSKIISVQNFTEDPVTKAID
                     VNNVLDKTGHGTSVVGQMSSNGYYTGIAPGMKVRMYKVFEEGNAQDEWILKAIIQAAK
                     DDVDVINLSLGQYLLKASSNIDEDRTALINSYQRAINYAHKQGSVVVASVGDEGANLN
                     NQAELKNLVSALTGRAFSSVDGTIEDIPAQLDNVVTVGSVDGDGAISNFSNRGRNVVD
                     IFAAGGGSKKLALHGYDTWINNKLFEQDWVIIPTLEGKYTYGYGTSIAAPKVAAALGL
                     IIEKYDLKDKPDEAITILYSNSWSSLDDNGKPIRLLNITDFISK"
     gene            1306..>1579
                     /locus_tag="TV188_001990"
     CDS             1306..>1579
                     /locus_tag="TV188_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEL1535294.1"
                     /translation="MYKILVVDDDYEILKLMRTILEMKNYKVTTYQEVTFPINFRDFQ
                     GFDLILLDVMMPNVEGTQICQLIRDKVASPIIFVSAKDTEDDIIKGL"
BASE COUNT          543 a          208 c          326 g          502 t
ORIGIN      
        1 tataatattc ttataaaaga aagcttagat accaataagg taaaaaagca attaaatgat
       61 cagggaatga tagtgcttga tgaaattcct gaaattaatg ttttgacaat cgctgctgca
      121 aatgactcat ctatgatttt ggaaaagaat tgtaactata ttgatgacat ttcaaggaat
      181 aatactttta cagtaaatcc caaaatgaca tatcagtttg ggcatgcatt ttatttagat
      241 agtgatttaa attactggaa taaacaatgg gatatgcaaa gaagtattag tactagtagt
      301 aggttttggc ataagtcatc aggtgaggta accattggtg taatagattc tggtattact
      361 gataataata ctgacatttc ttcaaagatc atttctgttc aaaattttac ggaggatcca
      421 gtaactaagg caattgatgt taataatgtt ttggataaaa caggtcatgg tacatctgtt
      481 gttggacaaa tgtcttcaaa tggttattat acaggaattg ctccaggcat gaaggttaga
      541 atgtataagg tgtttgaaga gggaaacgct caagatgaat ggattttaaa agcaattatt
      601 caagcagcaa aggatgatgt tgatgtcata aatttgagtc ttggtcagta tttattaaag
      661 gcttcatcaa atattgatga agatagaact gctctaatca atagctatca acgggcaatc
      721 aattatgcac acaaacaagg ctcagtggta gttgcttctg ttggtgatga gggagctaac
      781 ttaaataatc aagctgagct taagaactta gtcagtgctc tcacaggaag agcgtttagt
      841 tcagtcgatg ggacaataga ggatattccc gcacagctag ataatgttgt gacagtagga
      901 tctgttgatg gtgatggtgc aatatctaac ttttccaatc gtggaaggaa tgtcgttgat
      961 atctttgcgg caggtggagg aagcaagaag ctagcgcttc atggctatga cacttggatt
     1021 aacaataaat tatttgagca agattgggtt attatcccaa cactagaagg gaaatatact
     1081 tatggctacg ggacctctat tgcagcccct aaagtagctg ctgccttagg tttaatcatc
     1141 gaaaaatatg atttaaaaga taaaccagat gaggccataa ctattttgta tagtaactct
     1201 tggagtagct tggatgataa tggaaaacca attagattgt taaatattac agattttatc
     1261 tcaaaatagt gtaaaataac agtgtaacta ttatgaggta agactatgta taagattcta
     1321 gttgttgatg atgattatga gattttaaaa cttatgcgga ccattcttga gatgaaaaat
     1381 tacaaggtaa caacctatca agaagtgact tttccaatca attttagaga ttttcaaggg
     1441 tttgacttga ttttattaga tgtcatgatg cctaatgttg aaggtacaca aatttgtcaa
     1501 ttaatccgag ataaagttgc ttctcctatt atctttgtta gtgctaaaga tactgaagac
     1561 gatattatta aaggattaa
//
LOCUS       DARYYD010000126         1577 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.127, whole genome shotgun sequence.
ACCESSION   DARYYD010000126 DARYYD010000000
VERSION     DARYYD010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1577
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.127"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(494..1360)
                     /locus_tag="TV188_001991"
     CDS             complement(494..1360)
                     /locus_tag="TV188_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="HEL1535295.1"
                     /translation="MQYMGEMFKLLRTSRHISLKEATGDDFSHSMLSRFENGESDITI
                     SKLLVGLSNIRTELNEFIYLANGFKPSPYAVLKQEIWEAISKKDLSSLHQLYTKELEQ
                     YHLYKKDIYFLNALMIKSQMLFLDENIKMTPDEQSFLYDYLFSVEIWGIYELQLFSDI
                     SPLLSLDVYLRYTREMLGRVDFFEELWQHRNLVHSILLNGLFKATQEKRLGIAAYFDK
                     MINNHFFEENDTYLRIVYMIADGQHLYCKGEKELGLKQINDAIHILKALNCDESAAYY
                     SDSLEKWLKEVE"
BASE COUNT          487 a          313 c          222 g          555 t
ORIGIN      
        1 ctggatgctc catgattgtc ttaactttct tttccacgta ggcttcaaag cttttttcaa
       61 agctacttga acactcacga gaatcttctt tatagataca tttttaagta atcattggtt
      121 ttctcatagc aatacatctc ctcagtctta ttagtataaa actaaaaacg ctcacattaa
      181 caggtctttt tgagcgtttt tagtaggact agttactaaa ttatggtttg tagattggac
      241 atttccaagt cacaacaaag cctttcactg gcgcaaagca tctactagcc tcgtatgcaa
      301 attgagtcat gtttgtgatc tcctttcatt cttgatgagt ctagtgtatc atcaaaaacc
      361 gtaccaaagc taaactgttc atatgttcaa atcatggttt tgacattaat caaaaaacag
      421 tagctcaaaa agccactgtt tgctactagc taagcatcta aaccattttg cttatcaatg
      481 ctttaagttg catttattca acttccttta accatttctc taaactatct gaataatagg
      541 ctgcactttc atcacaattt aatgccttta agatgtgtat ggcgtcattt atttgcttta
      601 agcctagttc cttttcccct ttacaatata ggtgctgacc atcagcaatc atataaacaa
      661 ttcttaagta ggtgtcattt tcttcaaaaa aatgattgtt aatcatttta tcaaaatatg
      721 cagctatacc tagccttttt tcctgagtag ctttaaacag cccatttaat aaaatgctgt
      781 gcactaaatt tcgatgctgc caaagctcct caaaaaagtc tactcttcct agcatttctc
      841 gagtataccg caaatacaca tccaaggata ataagggaga aatatctgaa aataattgta
      901 attcgtatat tccccaaatc tccactgaaa acaaataatc atataaaaag ctttgctcat
      961 ctggagtcat tttgatattc tcgtctaaaa agagcatttg gcttttaatc atcaaagcat
     1021 ttaaaaaata gatatccttt ttgtataaat gatactgctc cagctctttt gtatacaatt
     1081 gatgtaagct ggacaggtct ttttttgata tggcctccca gatctcttgc tttaggacag
     1141 catatgggga aggcttaaag ccatttgcta gatagataaa ttcattgagc tctgtccgaa
     1201 tattgctaag tccaaccaat agctttgaga ttgttatatc ggattcacca ttttcaaatc
     1261 tgcttaacat cgagtgagaa aagtcatctc ccgtcgcttc ctttaacgat atgtgtcgcg
     1321 atgtccgcag taatttaaac atttctccca tatattgcat atcaatacct cttcaatctt
     1381 tcattttagt atagtatata accttaaaaa tgtaaatcca gtcttgattg cataaacctt
     1441 taattcaacg tttgatgcta ctaaatatcc tatttttctg aagtagatcc tcatctttat
     1501 gctataagca cttgctgcgt tttagaaaat gggctaaatc agctatactc ctttttaata
     1561 acaaaaaagc cttattt
//
LOCUS       DARYYD010000127         1534 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.128, whole genome shotgun sequence.
ACCESSION   DARYYD010000127 DARYYD010000000
VERSION     DARYYD010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1534
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.128"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            210..650
                     /locus_tag="TV188_001992"
     CDS             210..650
                     /locus_tag="TV188_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535296.1"
                     /translation="MIPKFRAFNKKTKKIYGVDGFKVSERRIYRCSLADDEFRSGRLE
                     TFHFVEDNLDDYILMQSTGLKDKNGVEVFDGDIVKCCRLFNDSLSEYVGQVKFVDFGW
                     NIVDKADTHEPFYNYKDGCPDEIREIEVIGNIYQNSELLESVEE"
     gene            647..853
                     /locus_tag="TV188_001993"
     CDS             647..853
                     /locus_tag="TV188_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535297.1"
                     /translation="MTVKELIEKLQEYPDYLTVELVLEDVDLVEAAHEADNVLSANII
                     TYDEKTLGVEQVSIDKLIISATGC"
     gene            864..1091
                     /locus_tag="TV188_001994"
     CDS             864..1091
                     /locus_tag="TV188_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017771078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535298.1"
                     /translation="MTKDDFLTGFVLTLLAACIFAVGFVFGSDCSSEHYEQQITDLRM
                     QLVSTQQQLKRASEDRARRTKRIAELTGNGG"
     gene            1095..1238
                     /locus_tag="TV188_001995"
     CDS             1095..1238
                     /locus_tag="TV188_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535299.1"
                     /translation="MIDEILKRLNKEFDNDLYNYEQERYAGYMDAIGVAIEIVEEVKR
                     GTK"
     gene            1235..>1534
                     /locus_tag="TV188_001996"
     CDS             1235..>1534
                     /locus_tag="TV188_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEL1535300.1"
                     /translation="MNIEEAIKYFEDKRKDYIVSPSVIHVSTVEVINILKQIKLDKPK
                     PEIPQFVADYIDDMHKNARTLRYAFKYMESNIKMHKWCVFERQETFVNAFLYGYTI"
BASE COUNT          544 a          213 c          350 g          427 t
ORIGIN      
        1 acccacgcag ttactgataa aaatttattt acagagtata catttgcgac gcagcaagat
       61 gccgagaatt atatcagaga cttagagcta aacggatcta agtgtgccct ttgagtatta
      121 tgagaggaga tttgcaaaat gagtgacgag gtcatgatct atttaatcgc agtagtttgt
      181 attttagcat tgcacaggag gaaataacga tgataccaaa atttagagca tttaataaaa
      241 agaccaaaaa aatttatggc gttgacggat ttaaagtaag cgagcgcaga atatacagat
      301 gcagcttagc tgatgatgag tttcgctctg gtcgcttaga gacgtttcat tttgtcgagg
      361 ataaccttga tgattatatt ctcatgcaat caacaggcct aaaagacaaa aacggcgttg
      421 aggtgtttga tggggatatc gttaagtgtt gcagactttt taacgactct ttgtctgagt
      481 acgtaggaca agtaaaattt gtagattttg gttggaacat agttgataaa gcagatacac
      541 acgagccatt ttacaactac aaagacgggt gtccagacga aattcgggaa atcgaagtta
      601 tcggaaacat ataccagaac agtgaattac tagaaagcgt ggaagaatga cagtaaaaga
      661 attaattgaa aaattacagg aatatccaga ttatctgacg gttgagttag tgttagaaga
      721 tgttgatttg gtggaagctg cacacgaagc tgataatgtg cttagtgcga atatcataac
      781 atatgacgaa aaaacgcttg gtgtagagca agttagcata gataaattaa ttatttcagc
      841 aacgggttgt taggaggctg atcatgacta aagacgactt tttaacaggt tttgtactta
      901 cacttttagc tgcttgcatt tttgcagtgg gatttgtgtt tggatctgac tgtagtagtg
      961 agcactacga gcaacaaata acagacttgc gtatgcagct tgttagcacg cagcagcaac
     1021 ttaagcgtgc gagtgaggat agagcaaggc ggactaaaag gattgccgaa ttgacaggta
     1081 atgggggata gggtatgatc gacgaaattt taaaaagact taataaagaa tttgacaatg
     1141 atctgtataa ttacgaacaa gaaagatacg ctggttatat ggacgcaata ggtgtagcaa
     1201 ttgaaattgt tgaagaagtt aagcgaggta caaaatgaac atcgaagaag cgataaagta
     1261 ttttgaagat aagagaaaag attatattgt atcaccaagt gtaatacatg tatcgactgt
     1321 tgaggtcata aatattttaa aacaaattaa gttagataaa ccaaagccag aaattccaca
     1381 gtttgtcgct gactacatag atgatatgca caaaaacgca cgtacattga gatacgcttt
     1441 taaatacatg gaaagtaaca taaaaatgca caaatggtgt gtttttgaaa ggcaagaaac
     1501 gtttgttaat gcttttttat acggatatac aata
//
LOCUS       DARYYD010000128         1517 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.129, whole genome shotgun sequence.
ACCESSION   DARYYD010000128 DARYYD010000000
VERSION     DARYYD010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1517)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1517)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1517
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.129"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(16..537)
                     /locus_tag="TV188_001997"
     CDS             complement(16..537)
                     /locus_tag="TV188_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015986726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4065 domain-containing protein"
                     /protein_id="HEL1535301.1"
                     /translation="MHALFVANYIIEYSNKKGYPINNLKLQKLLYFVNVRNILENGAP
                     LFEESMEKWKYGPVVPDVYHEYKRFGAFSISTDEMIMEYVEFSHSPFADLEITEYNPE
                     NVENTGLIENTVAALNNRDPFELVNITHRHTPWKKDEDRIMEGIQGIKYTIEEIKDYF
                     GNHPEEKLWVQCH"
     gene            complement(690..>1517)
                     /locus_tag="TV188_001998"
     CDS             complement(690..>1517)
                     /locus_tag="TV188_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1535302.1"
                     /translation="ELLIQLIEQNDLQKWDAEALAKRKESQMISSQCREVIEFYINLA
                     NAGMGVDKDGAYGTQCADVPCYAAKHWFGVDLWGNAADLLDSASAQGWEVHRMPTDAN
                     PRAGAFFVMDAWFGGINYGHTGLVYVDSDGYTMQTIEQNIDGNADALYVGGPARFNTR
                     DFTNVAGWFYPPYQGDVAAQTVSTDPQTSDTIVETPKTGTFTLDVAEINIRRWPSLAS
                     EVVGSYKQGDTVNFDSEGYANGYYWISYVGGSGKRNYLAIGQTDKDGNRISLWGKLN"
BASE COUNT          426 a          358 c          259 g          474 t
ORIGIN      
        1 atgaatcaat aacttttaat ggcattgaac ccatagtttc tcctcgggat gatttccaaa
       61 ataatctttg atttcttcaa tagtatattt aattccttga ataccttcca ttattctatc
      121 ctcatccttt ttccaaggtg tgtgtctatg agtaatatta acaagttcaa atggatcacg
      181 attatttagg gcagccaccg tattctcaat caatccagta ttctcgacat tttctggatt
      241 gtattcggtt atttctaggt cagcaaatgg gctatggctg aattcaacat attccataat
      301 catctcgtct gtagagatgg aaaaagctcc aaaacgttta tattcatgat agacatcagg
      361 aacaactggt ccatacttcc acttttccat actttcttca aaaagaggag ctccattttc
      421 aagaatattt cttacattca cgaagtataa taatttttgc aatttaagat tattgattgg
      481 gtagcctttt ttatttgaat actcaattat ataatttgca acaaataatg catgcatctc
      541 aattacacct cctttttctt aattataaca tatttgtcaa gtactatatc ttgttagcta
      601 aaaaattagc taacactaca tattgatttt gataacaaaa atacccccgc aaaagcgagg
      661 gcatttgtct tatctcggag ctttacctcc taatttaatt tcccccaaag gctgatacgg
      721 tttccatctt tatcagtctg tccaatcgct aggtaattac gcttaccaga gccaccgaca
      781 tagctaatcc agtagtagcc attagcgtag ccctcgctgt caaagttaac ggtgtcacct
      841 tgcttatagc tgcctactac ttcgctggcg agacttggcc aacgtctaat gttaatctct
      901 gcaacatcta gcgtaaaagt acctgttttt ggagtctcta cgatcgtgtc tgaggtttgc
      961 gggtctgtgc tgaccgtttg tgcagcaaca tctccctgat aaggaggata aaaccagccg
     1021 gccacattag taaagtcacg agtattaaaa cgggccggac cccctacata caacgcatct
     1081 gcattaccat caatattttg ctcgatagtc tgcatagtgt aaccatctga gtcaacgtac
     1141 acaagacccg tatgaccata attgatacca ccaaaccaag cgtccatgac aaaaaatgcc
     1201 ccagctcgtg gatttgcatc tgtaggcatg cgatggactt cccagccctg cgcacttgcg
     1261 ctatctagta agtccgctgc gttgccccag agatcgacac caaaccagtg cttagctgcg
     1321 taacaaggga catctgcaca ttgcgtgcca taagccccgt ccttatcaac acccatacca
     1381 gcattagcca aattgatgta aaactcgata acctctcgac actgcgaact aatcatttgt
     1441 gactcctttc tttttgctag ggcttccgcg tcccattttt gtaggtcgtt ttgctctatt
     1501 agttggataa gcagctc
//
LOCUS       DARYYD010000129         1503 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.130, whole genome shotgun sequence.
ACCESSION   DARYYD010000129 DARYYD010000000
VERSION     DARYYD010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1503
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.130"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            71..1468
                     /locus_tag="TV188_001999"
     CDS             71..1468
                     /locus_tag="TV188_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HEL1535303.1"
                     /translation="MIESKKYLVIKAVCEGKKQKNRACVELGLSKRQVNRLILAYREK
                     GKSAFVHGNRSKRPTHAMSLETKRRIIEKYQSYGDLRPNVVHFCELLAEEENIAYSDT
                     TVRKLLYQAGFLSPKTQRATKRRLKQEAKQKKREAEKRGSKLPTASNFFEEPDKAHPS
                     RARKKFKGELIQMEASQFPWFGQQETHLHVAIDDASGDIVGAYFDTQETLNGYYHVLE
                     QILEVHGIPFQFLTDKRTVFTYASSQSKKIEEDTFTQFGYACHQLGIAIETSSIPQAK
                     GRVERLNQTLQSRLPIDLQRNQITSISQANRYLKRWIKRFNKQFGGLASESVFEKAPK
                     PAQRNLLLARISERVIDSGHHIRYQNNFYLPVEGDKKIYFTRKTKALVIEAFDGDIYL
                     NIADNIYATRKLPKHEKHSKEFEMVPKTKKERRKYIPPQSHPWKLASFKQYLHKIGKS
                     YEEFKRERNTSQPQL"
BASE COUNT          530 a          300 c          299 g          374 t
ORIGIN      
        1 gtcttagcta ggtcgaatgt gaaaatgtcc cgtctgttaa actagaaaga tgaggaaaat
       61 agaactaact atgatagagt caaagaaata cctagtcatc aaagctgttt gtgagggtaa
      121 aaaacagaaa aacagggctt gtgtagaatt agggttaagc aagaggcagg tgaaccgatt
      181 gatactagcc tatcgagaga aaggaaagtc agctttcgtt catggtaata gatcaaaaag
      241 accaactcat gccatgtctt tagaaacaaa gagaaggatt atcgagaaat atcaaagtta
      301 cggtgattta agaccaaatg ttgttcattt ctgcgaacta ctagcggaag aagaaaacat
      361 cgcctattca gatacaactg ttagaaaact actctaccaa gcagggtttc tatctccaaa
      421 gactcaacga gcaacgaaaa gacgattgaa acaagaagcc aaacaaaaga aaagggaggc
      481 agaaaaaaga ggatccaaac tcccaactgc ttccaacttc tttgaagaac ctgacaaagc
      541 tcatcccagc cgagcaagaa agaaattcaa aggggaactc attcaaatgg aggccagtca
      601 attcccttgg tttggacaac aggaaacaca tcttcatgtc gctattgacg atgcctccgg
      661 tgatattgtc ggggcttact ttgatactca ggagacgcta aacgggtatt atcatgtctt
      721 agaacagatt ctagaggtac atggtatccc tttccagttc cttactgata aaaggactgt
      781 attcacttat gcttccagtc agtctaaaaa gatcgaggaa gataccttta cacagtttgg
      841 atatgcttgc catcagcttg gtattgccat tgaaacgtct tctatccctc aagctaaagg
      901 gcgtgtagaa cgtcttaatc agacccttca atcgcgtcta ccaattgatt tacagaggaa
      961 tcaaattacc agcatctctc aagcgaatcg ttatcttaag agatggatta aacgatttaa
     1021 caagcagttt ggtggactgg ccagtgagtc tgtttttgag aaagcaccta aaccggccca
     1081 gcgaaaccta ctgttagcga gaatctctga aagagtaatt gatagtgggc atcatattcg
     1141 atatcaaaac aacttctact tgcccgtcga aggggataaa aaaatctatt ttacgcgtaa
     1201 gacaaaggca cttgtgattg aggcattcga tggagacatc taccttaata tcgcagacaa
     1261 tatttatgcc actagaaagt taccaaaaca cgagaagcac tccaaagaat tcgaaatggt
     1321 gcctaaaact aaaaaagaaa gacgcaagta tattccacca caatcccatc cgtggaaact
     1381 tgcatctttc aaacaatacc ttcataaaat cggaaaatct tatgaagaat tcaagcgtga
     1441 gaggaatacc tctcaaccac aattataaca gatttttctc ttatctaacc gattttttca
     1501 aga
//
LOCUS       DARYYD010000130         1502 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.131, whole genome shotgun sequence.
ACCESSION   DARYYD010000130 DARYYD010000000
VERSION     DARYYD010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1502
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.131"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..>1502
                     /locus_tag="TV188_002000"
     CDS             <1..>1502
                     /locus_tag="TV188_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535304.1"
                     /translation="KSFRNISIADSKDKLNDFENVKSMSLLTSKDISLIPFENVNKEK
                     VNGDYHVRGTEENINKFIEEINQNEKLKTEVVVNPDFIVSSEFTQKQAYLYMLTIFII
                     FVATVFCLIIYNGMLSKELSISILLGCDELTLAIAKVLNILAIPAIVGLVLTIGIIEY
                     LVAPSDILGFMISMKTILILVAFIIGGLISIEFILIYLKLKGINVIALLKGYRRSYHR
                     SSFFIKTGSIVMVLYLAIVSILGLTDYLSMRQYIPTWESSKYYANMACAWSWSYEKDD
                     DKFHEIVIPKLNNLWNSLDDSGAILFNAPNVRKEGMNDDEEYLNQQPFQGNYAYVNKN
                     YLHIANLLDKDTNKIEQYKIHENEWIVFVPEDVKITELDKEKIHEDHIFQNIKKQGTI
                     IETYVRLKDNQSVFSFDSGKRIDEANLKNYVLVAVNGKELLPDHGIKLSSLVNGQLHP
                     YVKEPSRAYESLKDIIEETESEPFILYISSVYDDIVSRIDEYKMEASIYV"
BASE COUNT          570 a          168 c          272 g          492 t
ORIGIN      
        1 gaaatctttt agaaatatat ctattgctga tagcaaagac aaattgaatg attttgagaa
       61 tgtaaaatca atgagtttgc tgacatcaaa agatataagc ttaattcctt ttgaaaacgt
      121 caacaaggaa aaagttaatg gggattatca tgtaagaggg acggaagaaa atattaataa
      181 gtttattgaa gaaataaatc aaaatgaaaa attaaaaaca gaagtcgtgg ttaatccgga
      241 ttttattgtt tctagtgaat tcacacagaa acaagcatat ctatatatgc ttacgatttt
      301 tattatattt gtagctactg tcttttgtct aattatttat aatgggatgc tttcaaagga
      361 attatcgata tcaattttac taggatgcga cgaattaact ttagctattg ctaaggtttt
      421 aaatattctt gcaataccag caatagtggg acttgtactg acgattggaa ttatagaata
      481 tttagttgct cctagtgata ttttaggatt tatgatatca atgaaaacaa tacttatttt
      541 agttgctttt ataataggag gtctaatatc aatagagttt atattgattt atctcaaatt
      601 aaaaggaatt aatgttattg ccttattgaa aggttataga agaagttatc atagaagttc
      661 tttttttata aaaacagggt cgattgttat ggttctttat ctagcaattg taagtatttt
      721 aggactcact gattacttga gtatgagaca atacattcca acttgggaaa gctcaaagta
      781 ttatgcaaat atggcttgtg catggtcttg gagttatgaa aaagatgatg ataagttcca
      841 tgaaattgtt attccaaagc tgaataactt atggaatagt ttggacgata gtggagcaat
      901 attatttaat gccccaaacg ttagaaaaga gggaatgaat gatgatgagg agtatctaaa
      961 tcaacaacct tttcaaggta attatgccta tgtaaataaa aattatttac atattgctaa
     1021 tctcttagat aaagatacga ataaaataga acaatataaa atacatgaaa atgagtggat
     1081 tgtttttgtt ccagaagatg ttaaaattac tgaacttgac aaagaaaaaa ttcacgaaga
     1141 tcatattttt caaaatataa aaaaacaagg tacaattata gaaacatatg taaggctgaa
     1201 agataatcaa agtgtatttt cttttgatag tggcaaaaga attgatgaag caaacttgaa
     1261 aaattatgtt ttggtagcag taaatgggaa agaattactc ccagatcacg gaatcaaact
     1321 atcatcttta gtaaatgggc agctacatcc atatgttaaa gagcctagta gggcatacga
     1381 gagtttgaag gacataattg aagaaacaga atctgagccg tttatactct atatcagctc
     1441 agtttacgat gatatagttt caagaataga cgaatataag atggaggcaa gtatatatgt
     1501 ta
//
LOCUS       DARYYD010000131         1471 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.132, whole genome shotgun sequence.
ACCESSION   DARYYD010000131 DARYYD010000000
VERSION     DARYYD010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1471
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.132"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..265)
                     /locus_tag="TV188_002001"
     CDS             complement(<1..265)
                     /locus_tag="TV188_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1535305.1"
                     /translation="MTFLDDIKQGCLDGWTKYKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWTGKSFNTKTQEEYQPGVVTDIVDRFRAYDSWDESI"
     gene            complement(382..753)
                     /locus_tag="TV188_002002"
     CDS             complement(382..753)
                     /locus_tag="TV188_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEL1535306.1"
                     /translation="MFIFLRQLIQTQDGKILFTLGAIAVAMMIDFLTGTVAAKINPNI
                     DFRSKEGINGILRKICSIALMIFFIPLSILLPNDTGVAFLYVMYVGYLLFELKSILEN
                     LNKMGIDVALFKQFIDMFSKK"
     gene            complement(765..1376)
                     /locus_tag="TV188_002003"
     CDS             complement(765..1376)
                     /locus_tag="TV188_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1366 domain-containing protein"
                     /protein_id="HEL1535307.1"
                     /translation="MRNWKVTGKYPQFDSTGAVASTHVIITAEDGSVISQPIKQDLTS
                     TNDTEIIKATLEEFKKSEYVEIAMGEAVQKVDDLEKLSQETAKTATTAQAAAGLAKVS
                     AERTQKMINLQTIHMLTSVDKIEPDIYKGMLELIEPAKKGQYQEHDVFTVLDDKHEDL
                     AGEGNLVFVYVNEAFTYDKQTLKDLESEDKVTVIKYADLVKGK"
     gene            complement(1380..>1471)
                     /locus_tag="TV188_002004"
     CDS             complement(1380..>1471)
                     /locus_tag="TV188_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1617 family protein"
                     /protein_id="HEL1535308.1"
                     /translation="AEAEDEFTGAEIILIDNILEQYEANKKGE"
BASE COUNT          384 a          341 c          281 g          465 t
ORIGIN      
        1 ggatcgactc gtcccagcta tcataggccc taaaacgatc tacaatatcc gttacaacac
       61 ccggctgata ctcctcctga gtttttgtat taaatgactt acccgtccaa gagctatctg
      121 ccttgatacc aaatagagcg ttatgtgggg cgtacttgcc ccaaccactc tcaaggattg
      181 cctgtgctgc ggtcaacgat ggcaagattt tatactttgt ccagccatct aagcagcctt
      241 gcttaatgtc atctaaaaag gtcatctgtc ctccttatct aaaaacggat aaacaatcag
      301 agcaatcaca gacagcggca catatagcac tgcgattgct aggactattg ctaatcgtgt
      361 gattgctcgc atgagatcct cctatttttt actaaacata tcaataaatt gcttaaacag
      421 tgcgacatca atccccattt tgtttagatt ttctaagatt gattttagct caaagagcag
      481 atagccaacg tacatgacat acaaaaaggc tactcctgta tcatttggca gtaaaatcga
      541 caaagggata aaaaagatca tcagggcaat tgagcaaatt ttgcgcaaaa taccattaat
      601 cccctctttg ctcctaaaat caatgttggg gttaattttt gctgcaacgg tacccgttaa
      661 aaaatcaatc atcattgcga ctgcaattgc tcctaaagta aataggattt taccatcttg
      721 ggtctggatt aattgtctca aaaaaataaa catggatcac ctcactattt gcctttaacc
      781 aaatcagcgt atttaatcac tgtgacttta tcctctgatt ccagatcttt gagggtttgc
      841 ttgtcatagg taaaggcctc attgacatac acaaagacaa gattgccctc accggccaaa
      901 tcctcgtgct tgtcgtctag cacagtaaaa acgtcgtgct cctgatactg accttttttg
      961 gctggctcga taagctctag catgcctttg taaatgtcag gctcgatctt atcgacgctg
     1021 gtcaacatgt ggatagtttg caagttaatc atcttttgcg tgcgctctgc ggacacttta
     1081 gccagaccag ctgccgcttg tgcagttgtt gctgtcttag cagtttcctg cgatagtttt
     1141 tccaagtcgt ccactttttg caccgcttcg cccatggcga tttccacgta ttcggatttt
     1201 ttaaattctt ccaaggtagc tttgatgatc tctgtgtcat tagttgaggt taagtcctgc
     1261 ttgattggtt gagagatgac tgagccatcc tctgctgtaa taataacgtg agtgcttgcg
     1321 actgctcctg tgctgtcaaa ttgtgggtat tttcctgtga ctttccaatt gcgcataatt
     1381 tactctcctt ttttatttgc ttcgtactgc tctaaaatgt tgtcgattaa gatgatttcg
     1441 gcccctgtaa actcatcttc ggcctcggcc a
//
LOCUS       DARYYD010000132         1316 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.133, whole genome shotgun sequence.
ACCESSION   DARYYD010000132 DARYYD010000000
VERSION     DARYYD010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1316)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1316)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1316
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.133"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            185..988
                     /locus_tag="TV188_002005"
     CDS             185..988
                     /locus_tag="TV188_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEL1535309.1"
                     /translation="MRYTLNKNKRARNYGLCSAAIALAAVASLGTAGSAKAEEAKTLD
                     QLPNPEEQILYNYWDTNDQKAREYLGDLYGFLKSYLGELEKKAKEPGPAGPKGEKGEK
                     GEKGETGPMGPQGLKGEDGKDGAPGEKGEKGDPGIQGPKGEKGDQGQKGEKGDQGQKG
                     EKGDQGQKGEKGDQGQKGEKGDQGQKGEKGDQGIQGQGEHGHKGHHGKDAKPSAPKAD
                     SKSTAKAMAPAAQKGTLPATGETNHPFFTLAALGVIASAGMLTLKGKKN"
BASE COUNT          498 a          264 c          292 g          262 t
ORIGIN      
        1 caatgtcaat aacatcaatc aaaaatcaga cgattaggat tttgattaaa aaaaaaaaaa
       61 acgaaaccaa agattgaaat tgatagatag ctattcccac tctaatagtg gacatgttag
      121 aatttccttt gggaaaggaa gttacaggaa actaagactg tttctaccac aaaaggagag
      181 aaagatgaga tacacattaa acaaaaacaa gcgtgctcgt aactacgggc tatgctcagc
      241 agctatcgct ctagcagcag tagccagcct aggaacagct ggcagcgcta aagctgagga
      301 agcaaaaaca ttagaccaac tacctaatcc agaagagcaa attctatata attattggga
      361 cacaaatgat cagaaagcaa gagaatatct tggagaccta tacggtttcc taaaatctta
      421 tttaggagag ttggaaaaaa aagctaaaga gcctggacct gctggaccta aaggtgaaaa
      481 aggcgaaaaa ggcgaaaaag gcgagaccgg tccgatgggg cctcaaggcc taaagggtga
      541 ggacggaaaa gacggcgcac ctggagaaaa aggagaaaaa ggtgatccgg gtatccaagg
      601 ccctaagggg gaaaagggtg accaaggcca aaaaggtgaa aagggcgacc aaggccaaaa
      661 aggtgaaaag ggcgaccaag gccaaaaagg tgaaaagggc gaccaaggcc aaaaaggtga
      721 aaagggcgac caaggccaaa aaggtgaaaa gggcgaccaa ggtatccaag gccaaggcga
      781 gcatggacat aagggtcacc atggaaaaga tgctaagcca tcagcaccta aagcagattc
      841 taaatcaaca gcaaaagcta tggcgccagc agctcaaaag ggcacactac cagctacagg
      901 ggagacaaat cacccattct tcacccttgc agcccttggt gttatcgcta gcgccggcat
      961 gctaacatta aaaggcaaga aaaactaaac cagccattgc acctttcccc ttaggcaatg
     1021 agctagtaac agcttttctc atctcttcag gcagcattgc cctaagaaga tgacctaagt
     1081 tcaaaaagag gctatcacca gcctctcaaa ttgaaaaaag tccttagaaa ataatttcca
     1141 agggcttttc tttgtataaa gtcgtacaat aaaagaaaag gattgtacag tgttatctat
     1201 atttcataaa gacaaactag actataatcg taactgatac gttttttcta tgcgctaatt
     1261 tcttcaacct ctttaacaag atagttatga tactatttct agatcatcaa atatca
//
LOCUS       DARYYD010000133         1262 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.134, whole genome shotgun sequence.
ACCESSION   DARYYD010000133 DARYYD010000000
VERSION     DARYYD010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1262
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.134"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(169..242)
                     /locus_tag="TV188_002006"
     tRNA            complement(169..242)
                     /locus_tag="TV188_002006"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Asn,seq:gtt)
     gene            complement(275..346)
                     /locus_tag="TV188_002007"
     tRNA            complement(275..346)
                     /locus_tag="TV188_002007"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(311..313),aa:Glu,seq:ttc)
     gene            complement(359..432)
                     /locus_tag="TV188_002008"
     tRNA            complement(359..432)
                     /locus_tag="TV188_002008"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(396..398),aa:Ile,seq:gat)
     gene            complement(462..532)
                     /locus_tag="TV188_002009"
     tRNA            complement(462..532)
                     /locus_tag="TV188_002009"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(498..500),aa:Gly,seq:tcc)
     gene            complement(538..610)
                     /locus_tag="TV188_002010"
     tRNA            complement(538..610)
                     /locus_tag="TV188_002010"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(575..577),aa:Phe,seq:gaa)
     gene            complement(635..708)
                     /locus_tag="TV188_002011"
     tRNA            complement(635..708)
                     /locus_tag="TV188_002011"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(672..674),aa:Met,seq:cat)
     gene            complement(720..809)
                     /locus_tag="TV188_002012"
     tRNA            complement(720..809)
                     /locus_tag="TV188_002012"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(771..773),aa:Ser,seq:tga)
     gene            complement(817..890)
                     /locus_tag="TV188_002013"
     tRNA            complement(817..890)
                     /locus_tag="TV188_002013"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(854..856),aa:Ile,seq:cat)
     gene            complement(911..984)
                     /locus_tag="TV188_002014"
     tRNA            complement(911..984)
                     /locus_tag="TV188_002014"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(948..950),aa:Met,seq:cat)
     gene            complement(995..1068)
                     /locus_tag="TV188_002015"
     tRNA            complement(995..1068)
                     /locus_tag="TV188_002015"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1032..1034),aa:Pro,seq:tgg)
     gene            complement(1075..1148)
                     /locus_tag="TV188_002016"
     tRNA            complement(1075..1148)
                     /locus_tag="TV188_002016"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1112..1114),aa:Arg,seq:acg)
     gene            complement(1163..1247)
                     /locus_tag="TV188_002017"
     tRNA            complement(1163..1247)
                     /locus_tag="TV188_002017"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1211..1213),aa:Leu,seq:taa)
BASE COUNT          361 a          359 c          272 g          270 t
ORIGIN      
        1 tatcctacca tactatcccc taaaaagcaa ggctctatac catctggaat aggtaagtcc
       61 actgtggaaa tcatagagct ttttgagtac acaaaaaaga gagcaccaaa ctgatcctct
      121 ctaaatgtcc gttgttagtc aacccactat agttgacata gagccaaact ccgccagtag
      181 gactcgaacc tacgacatca tgattaacag tcatgcgcta ctaccaactg agctatgccg
      241 gaaaataaaa aaattgccac aaagacaatt ctgatagtcc gtacgggatt cgaacccgtg
      301 ttaccgccgt gaaaaggcgg tgtcttaacc ccttgaccaa cggaccatca tatcttaatg
      361 ggcacgagtg gactcgaacc accgacctca cgcttatcag gcgtgcgctc taaccacctg
      421 agctacgcgc ccaagcacac tatagcttgg gaaaactata aagcgggtga cgagaatcga
      481 actcgcgaca acagcttgga aggctgtagt tttaccacta aactacaccc gctaaaatgg
      541 cgcgagacgg aatcgaaccg ccgacacatg gagcttcaat ccattgctct accaactgag
      601 ctaccgagcc aaccagcata tatcttttat ataattgcgg gagcaggatt tgaacctacg
      661 accttcgggt tatgagcccg acgagctacc taactgctcc atcccgcgat aatctttaaa
      721 ggaggatgtg ggattcgaac ccacgcacgc tgttacacgc ctgacggttt tcaagaccgt
      781 tcccttcagc cggacttggg taatcctcca ccattatgga ccttgtagga ctcgaaccta
      841 cgaccgctcg gttatgagcc gagtgctcta accagttgag ctaaaggtcc aaaacaatcc
      901 aaaaacaaaa tagcggcgaa ggggatcgaa cccccgacct cccgggtatg aaccggacgc
      961 tctagccagc tgagctacac cgccatcaaa ctaatcggga agacaggatt cgaacctgcg
     1021 acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgta actatgcacc
     1081 ctagaggagt cgaacctcta accgcctgat tcgtagtcag gtactctatc cagttgagct
     1141 aagggtgctt ttccttatgc tatgccgagg accggaatcg aaccggtacg atgttaacca
     1201 tcgcaggatt ttaagtcctg tgcgtctgcc agttccgcca ccccggctcc ccaaaagcga
     1261 ac
//
LOCUS       DARYYD010000134         1202 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.135, whole genome shotgun sequence.
ACCESSION   DARYYD010000134 DARYYD010000000
VERSION     DARYYD010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1202
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.135"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            236..1202
                     /locus_tag="TV188_002018"
                     /pseudo
     CDS             236..1202
                     /locus_tag="TV188_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371017.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
BASE COUNT          449 a          135 c          229 g          389 t
ORIGIN      
        1 aatcatcatt gtgattactc acaaccaaga tataaaaacg ttagaacaat tcgatgaagt
       61 catttgtttg taaatgaaag ggggtgatga acatgattat ggaagatttt gaagttttag
      121 aactagagtt tgtcgaagtt cgaaatgaac aaaccacaaa ttggtatttt gtttaatcac
      181 aaaggcatgc aatgagaatt tgcatgcctt tgtaaaatat agaaaggaca ataaaatgaa
      241 taattttttt ccaaaatgga atcaggatag gattgtatat tcatggcaaa atgataaatt
      301 aaggatagga gctgatgata atgatgttct agaaatcaaa ggaaactcaa ttttttggtc
      361 agattttatt tcttgttgtg acgggaataa tagtatcaaa gacattcaaa aactattgaa
      421 tataaaatat aatatttcag aagaaataat tacagagtat ttagataaat tctcaaatcg
      481 aaatttattg gaaatattgg ataatccaat aaatcaatta caggattata aatcaattga
      541 gtcgttagaa acatattatg ctagtgaagg aattggtggg attaaactat taaaaatgtt
      601 agggaatcta aagatttcta ttctgggatg tggtggtggt ggatctcata ttgcattaca
      661 attagctcaa ttaggagtgg gaagaattca tttggtggat tacgatattg ttgaagaaaa
      721 caatatcaac agacaatcca tgttcacatt taacgatgtc ggaaattaca aagttgattg
      781 tgtagccaaa aatattcagc aaagaaattc taaatgtttg gttaccaaaa gcacttctaa
      841 aatgattaat gtacctgatg taaaaaaaag aaatatctga aagcgattgg gtattctgtt
      901 gcatggatga acctccttat atagcacaga ggattgtaaa tagagcatgt tatttattaa
      961 aaattccaag tatatactgt tttagccaac gtagtgcggg gaaacttttg ttttgtaatc
     1021 ctaatattga agattctggc tgtattgatt gtttgttatc tgaacaagat aatgaaaact
     1081 ttcaaaagct ggtgacaacg ttcactacct ataataggaa attggtaact gcaaatatct
     1141 taccaaatat tttattattg acatcgtggg tggttaaacg atggttagat tgtgtaacag
     1201 at
//
LOCUS       DARYYD010000135         1192 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.136, whole genome shotgun sequence.
ACCESSION   DARYYD010000135 DARYYD010000000
VERSION     DARYYD010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1192
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.136"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..273
                     /locus_tag="TV188_002019"
     CDS             <1..273
                     /locus_tag="TV188_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535310.1"
                     /translation="TIHVLTSGGKIEPDIYKGMLELIEPAKKGQYQEHDVFTVLDDKH
                     EDLAGEGKLVFVYVNEAFEYDKQTLKDLESEDKVTVIKYADLVKGK"
     gene            286..576
                     /locus_tag="TV188_002020"
     CDS             286..576
                     /locus_tag="TV188_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535311.1"
                     /translation="MIDFVQIGTFCGAALSIFGVWGFIVNPFKKALEANELAMAQLKD
                     SIKELAYELKNLDRDGEITKKIIDRHEERLGRVEDDIIVNKEQIKTLFKKGD"
     gene            579..758
                     /locus_tag="TV188_002021"
     CDS             579..758
                     /locus_tag="TV188_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535312.1"
                     /translation="MDKWFKKVAIKTIKTMAQTAVGVIGSSALITDVNWQVVASTVIM
                     SGIVCVLMNVSDIKE"
     gene            870..>1192
                     /locus_tag="TV188_002022"
     CDS             870..>1192
                     /locus_tag="TV188_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HEL1535313.1"
                     /translation="MTFLDDIKSAVIAEWHNHKILPSLTAAQAILESGWGKYAPHNAL
                     FGIKADSSWSGKSFDTKTQEEYQPGVVTDLVDRFRAYDSWDESILDHGQFLVDNPRYK
                     SVIGET"
BASE COUNT          363 a          215 c          290 g          324 t
ORIGIN      
        1 actatccacg ttttgacaag tggtggcaag attgagcctg atatctataa aggcatgctt
       61 gagcttattg agccagctaa aaaaggtcag tatcaagagc atgatgtctt tactgtgcta
      121 gatgacaagc atgaggactt ggccggcgag ggtaaacttg tctttgtcta tgttaacgag
      181 gcctttgagt acgacaagca aaccctcaaa gatctggaat cagaggataa agtcacagtt
      241 atcaagtacg ctgatttggt taaaggcaaa tagtgaggtg attagatgat agattttgtg
      301 caaataggca ctttttgtgg cgctgctctg tctatctttg gtgtttgggg atttatcgtc
      361 aatcctttta aaaaagcgct ggaggctaac gagctagcca tggcccaact caaagactcg
      421 atcaaggagc tagcctacga gctaaaaaat cttgatcgtg atggagagat aaccaaaaag
      481 attatcgatc ggcatgagga gcgtttagga cgtgtagagg acgacattat tgtcaataaa
      541 gagcaaatca aaacattatt taaaaaagga gactaaaaat ggataaatgg tttaaaaaag
      601 tagcaatcaa aacaattaag acaatggccc aaaccgctgt aggggttatt ggatcaagcg
      661 cattgattac tgacgtcaac tggcaggtgg tggcctcaac agttattatg tcaggtattg
      721 tctgcgtctt gatgaatgtg tctgacatca aggaatagca ttatgcgagc aatcacacga
      781 ttagcaatag tcctagcaat cgcaatacta tatttaccgc tatctgtgat tgctcttatc
      841 ttttatccgt ttttaggtga ggaggacaga tgaccttttt agacgacata aaaagcgcag
      901 ttatcgcaga gtggcacaat cataagattt tgccatctct gacggctgct caagctattt
      961 tagagagcgg ttggggcaag tatgccccac ataacgcatt gtttggtatc aaggcagata
     1021 gctcatggtc tggtaaatct tttgatacca agacacaaga ggagtatcag ccaggtgtcg
     1081 tgacggatct cgtggaccgc tttagagcct atgacagttg ggacgagtca atccttgatc
     1141 atggccagtt tttagtggat aatccacgat acaaatcagt tatcggggag ac
//
LOCUS       DARYYD010000136         1174 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.137, whole genome shotgun sequence.
ACCESSION   DARYYD010000136 DARYYD010000000
VERSION     DARYYD010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1174
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.137"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..365
                     /locus_tag="TV188_002023"
     CDS             <1..365
                     /locus_tag="TV188_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HEL1535314.1"
                     /translation="NRTRNNGIYLMLSDDELEILNKKYELSGCKSLRQFIMKCILEKD
                     IFVLDMKVFKEMSTNIGRITGSINQIAKRVNSTAVIYKDDINDLKKLLEKQGKDIYFL
                     RKKLYELGNFGTSGTEEI"
     gene            365..>1174
                     /locus_tag="TV188_002024"
     CDS             365..>1174
                     /locus_tag="TV188_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014262108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEL1535315.1"
                     /translation="MAVTKIHPIEKTLYLALDYIMNEDKTDEKILISSFGCNPKTAHL
                     EFEHTKKECNSKAKILARHLIQAFAPGETTPEQAHQIGLDLCERVLRGKYEYVLTTHI
                     DKGHLHNHILFNNVSFETGKAYQSNKRSYHQIRTVSDDLCRENGLSVIDENYKKFKNR
                     YSTNGKTYMEYTEFKKGNSWKNKLQLTIDKAVLKSKTYEEFLKTMEDFGYEIKIGKYL
                     SFRHKDKRDKGRFTRAKASTLGEDYTKERIKERIEDSNKQNIYVNQEYHYEK"
BASE COUNT          481 a          172 c          213 g          308 t
ORIGIN      
        1 caaacagaac aagaaataat ggaatatacc ttatgctttc tgatgatgaa cttgaaattt
       61 tgaataaaaa atatgaactg tccggttgta aaagtttaag acagtttatt atgaagtgca
      121 tccttgaaaa agatattttt gtactggata tgaaagtgtt taaggagatg tctacaaata
      181 tcggaaggat tacaggtagc atcaatcaga ttgcaaaaag ggtaaattca actgctgtaa
      241 tttacaaaga tgacatcaat gatttgaaaa agctcttgga aaaacaagga aaagacatct
      301 actttcttcg taaaaagcta tatgaattag ggaattttgg aacaagtggt acggaggaaa
      361 tctaatggca gttacaaaaa ttcatccgat agaaaaaaca ctttatctag cattagacta
      421 tattatgaat gaagataaaa ccgatgaaaa aatccttatc tcctcttttg gctgcaatcc
      481 caaaacagcc catcttgaat ttgaacatac aaaaaaagaa tgtaattcca aagcaaaaat
      541 cttggcaagg catctaattc aagccttcgc tccaggagaa actacacctg agcaggcaca
      601 ccaaatcgga ctggatctat gtgagagagt cttgagggga aagtatgaat atgtccttac
      661 aacacatatc gacaaggggc atctacacaa tcatattctg tttaacaatg tcagctttga
      721 aacaggaaag gcatatcaaa gtaataagag aagttatcat caaatccgaa cggtcagtga
      781 tgatttatgt agagaaaatg gcttgtcagt tattgatgaa aactacaaaa aatttaaaaa
      841 cagatactct acaaatggta aaacctatat ggaatatacc gaatttaaga aaggaaactc
      901 ttggaagaat aaactacaac ttactattga taaagctgtt ttaaaatcca aaacttacga
      961 ggaatttcta aagacaatgg aggatttcgg ttatgaaatc aaaataggaa aatacctttc
     1021 cttccgacat aaagataaaa gagataaggg aagatttacc agagcgaaag catctacttt
     1081 aggggaagat tatacaaaag agagaatcaa ggaacgaatc gaagattcaa ataagcaaaa
     1141 tatttatgtt aatcaggaat atcattatga aaaa
//
LOCUS       DARYYD010000137         1146 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.138, whole genome shotgun sequence.
ACCESSION   DARYYD010000137 DARYYD010000000
VERSION     DARYYD010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1146
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.138"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..490
                     /locus_tag="TV188_002025"
     CDS             <1..490
                     /locus_tag="TV188_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEL1535316.1"
                     /translation="PVMWIMMPSLIALFTGVPYMMICNKVQKAGAILIMGTVTVLIYY
                     ATGQFTTVILATFAVGCILAEIIRAITRYTSFIGNTLSFALFSIGMIGSPLPIWLFKE
                     SFFAHISEVGMSQDYINALEKFTSPAILIGVIILTFICSLVGALIAKRMMNKHFKKAG
                     II"
     gene            492..>1146
                     /locus_tag="TV188_002026"
     CDS             492..>1146
                     /locus_tag="TV188_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEL1535317.1"
                     /translation="MREYRLKIDPRAGISLLFILNFTIFNVSTVYALFVLLIWNCVYA
                     MCNGYCRIAIKFIFTYWLLYLIEFLVLPKLPSLIAISFAILLTYILKMLPVALFGYVF
                     VKTTSLYELITALRKIHFPESIITGLSITLRYFPALREDFHKTYDAMKLKNMSVLEKI
                     SGLIITTMTRATLNIEELSQAASVRGIDNPVKKFSAAEINFKTSDAVVFIVSSVVYIF
                     "
BASE COUNT          371 a          142 c          206 g          427 t
ORIGIN      
        1 accagttatg tggattatga tgccttcact gatagcttta tttacagggg tgccatacat
       61 gatgatttgc aacaaagttc aaaaagctgg tgctatttta atcatgggaa cagttacagt
      121 tttgatatat tatgcaacag gacaatttac aacagttatt cttgcaactt ttgcagtagg
      181 ttgtatatta gctgaaatta ttagagcaat tactagatat acaagtttta tagggaatac
      241 tttatcattt gcactatttt caattggaat gataggatcg cctcttccta tttggttgtt
      301 taaagaatca ttttttgctc atatatcaga ggttggtatg tcgcaggatt acataaatgc
      361 cttggaaaag tttacttcgc cagcgatttt gataggagtt attattttga cttttatttg
      421 ttcgttagtt ggggctttga ttgcgaaaag aatgatgaat aaacatttta aaaaagcggg
      481 aattatataa aatgcgtgaa tatagattaa aaatagatcc gagagcaggg atttccctgc
      541 tttttatctt aaactttacg atatttaatg tatccacagt ttatgcatta tttgtgctat
      601 taatttggaa ctgtgtttat gcaatgtgta atggatattg taggatagca atcaaattca
      661 tttttactta ttggttgctt tatttgatag aatttttggt tttaccgaaa ctaccaagtt
      721 taattgctat ttcctttgct attctattaa cttatatttt aaagatgtta ccagtagcat
      781 tgtttggata tgtttttgtt aaaactacaa gtttgtatga gttaattacg gcacttagaa
      841 aaattcattt tccagaaagt ataataacgg gattatcaat aactcttaga tattttccgg
      901 cattaagaga agattttcat aaaacatatg atgctatgaa actaaaaaat atgtctgttt
      961 tagaaaaaat aagtggactg ataattacta caatgacaag agccacatta aatatagaag
     1021 aattatctca ggcagcaagt gtaagaggca tagataatcc tgtaaaaaaa ttttctgcgg
     1081 ctgaaataaa ttttaagaca agtgatgcgg tagtgtttat agtgtcttct gttgtctata
     1141 ttttta
//
LOCUS       DARYYD010000138         1094 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.139, whole genome shotgun sequence.
ACCESSION   DARYYD010000138 DARYYD010000000
VERSION     DARYYD010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1094
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.139"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(44..754)
                     /locus_tag="TV188_002027"
     CDS             complement(44..754)
                     /locus_tag="TV188_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HEL1535318.1"
                     /translation="MAKKKGKLTLISLFVLVACLGVYSSIRQSENTSDVSAETVSTSS
                     TQAFIEEIGATASVVAQERDLYASVMIAQAILESANGKSALSQAPYYNFFGIKGAYNG
                     SSVTMTTWEDDGAGNTYYIDQTFRAYPTVADSLYDYTNLLSSDIYAGARKSNTLSYQD
                     ATAALTGLYATDTSYNWKLNNIIETYGLTAYDIVNNQAQEALAAAPLTSVWNPYRKSY
                     TDTETLAIDKAWAQRMGY"
BASE COUNT          325 a          217 c          183 g          369 t
ORIGIN      
        1 gctagaactc aagccttgga gtgctaagtc atttttctat tctttagtag cccattcgtt
       61 gtgcccatgc cttatcaata gcaagggttt cagtgtctgt atagctcttg cgataaggat
      121 tccagacaga ggtcaaagga gccgcagcaa gcgcttcttg cgcctgatta tttactatat
      181 cataggccgt tagaccgtag gtctcaatga tgttgtttaa tttccagtta tagctagtat
      241 ctgtagcata caagcctgtt aaagctgctg tagcgtcctg ataagacaag gtatttgact
      301 ttctagcacc tgcataaata tctgagctaa gcaaattagt gtaatcatat aaggaatcag
      361 ccactgtcgg ataagctcta aaggtttgat cgatgtagta agtatttcca gccccatcgt
      421 cttcccatgt tgtcatcgtc actgatgacc cattataagc ccctttaatg ccaaaaaaat
      481 tataataagg tgcttgactt aaagctgatt taccgttagc tgactctaaa atagcttgag
      541 caatcataac cgaagcatac aagtctcttt cttgagcaac aacactagca gttgctccaa
      601 tctcttcaat aaaggcttgc gttgacgacg ttgacacagt ctctgctgag acatctgatg
      661 tattttctga ctgtctaatt gaactataaa cacctaagca ggctactaga acaaaaagac
      721 tgataagtgt gagcttacct ttcttttttg ccatttatca ttccctcttt ttttgataaa
      781 tagattatag cacagaatgc tcataaaaag acttatccac aaacaattta atcatattga
      841 taacttttgt ctttaaatcg aaatatttta atgtaaagaa ggcttaccaa gtccataaag
      901 cgaaggcttt tcataatctt ttacgcctta tttgctatat cgccttgtaa tagcttcaat
      961 acctttgaaa ggttattaca cctactattg ttctttatgc ctgtctgtta agtattttcc
     1021 atttaactgc ctttattttt taggtaaaga aaaaacagta aaccattaat ttactgtttc
     1081 ttaattgata ttta
//
LOCUS       DARYYD010000139         1072 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.140, whole genome shotgun sequence.
ACCESSION   DARYYD010000139 DARYYD010000000
VERSION     DARYYD010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1072
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.140"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            259..1072
                     /locus_tag="TV188_002028"
                     /pseudo
     CDS             259..1072
                     /locus_tag="TV188_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          380 a          179 c          233 g          280 t
ORIGIN      
        1 aatagtatag ccgtttttct tgtattgcgc tatccacctt gaaagcatac tagaatttgg
       61 taaagcatag tctaaggacg tctgtttttg agattgaccc gcaccccaaa agttagacag
      121 aaaatctacc aatggggtgc tttttatatg aaattaagtt acgatgataa attaagaata
      181 tatgaactaa gaaaaaatgg gatgtcttgt tcccgcattg gtcaacagta tgatattcag
      241 gtttctaatc tcaaatacat ggtaaagctt atggacagat atggagttga gattgttaga
      301 aagggtaaaa ataagtatta tcctccagaa ttaaaacaag aaataattga taaagttctt
      361 cttgaaggtc agtctcaact gtctgtctct cttgagtatg ctctcccaaa tgctggtatg
      421 cttcccaatt ggatagcgca atacaagaaa aacgggtata ctattcttga gaaacaaaga
      481 gggagaccaa cgaagatggg ccgtaaacca aagaaaactt gggaagaaat gacagagcta
      541 gagcgccttc aggaagagct agaatacctt agaacggaga atgcttatct aaaaaagttg
      601 agggagcttc gtttacagga cgaagccaga gaatgagaaa ggcagaaaca attagagaga
      661 tggtccaaga aggattccga ttaaacctcc tacttgagat cgctaagatg gctcgttcaa
      721 cctattatta tcaagtcaag caattggata agtcagataa agatgaagca atcaactctg
      781 aaatcaaagc gatttatgag gagcataagg gaaactatgg ttaccgtcgc attcatttag
      841 aactcaagaa tcgtgggttt atcgtcaatc acaagaaagt gcaacgcttg atgaaagaga
      901 tgagattagc tgctcgaatt cgtcgtaaac gcaggtattc ctcttacaaa ggcgagactg
      961 gtaagaaggc tgataatctg attcaacgcc agtttgaagc tgctaagcca tatgaaaaat
     1021 gttataccga tgtgacagag tttgctttac caaacaacga tgaaaaactt ta
//
LOCUS       DARYYD010000140         1038 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.141, whole genome shotgun sequence.
ACCESSION   DARYYD010000140 DARYYD010000000
VERSION     DARYYD010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1038
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.141"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            145..1038
                     /locus_tag="TV188_002029"
                     /pseudo
     CDS             145..1038
                     /locus_tag="TV188_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSeq3 family transposase"
BASE COUNT          355 a          190 c          221 g          272 t
ORIGIN      
        1 gacataaaat ctaacaattg gggggctatt tttatgacat tgagttatga agacaaggtt
       61 caaatctatg agctacggca cattggaaag tccattaaat gcttatcaga aaagtttagt
      121 attgcagaat ctgacctcaa atacatgatt cgcctgattg acaggtatgg gttagccatt
      181 gtccaaaaag gtaagaatag ttattattct ccagaactga agcaagagat aatagataaa
      241 gttctgattg atggtcaatc tcaaaaacag acgtccttag actatgcttt accaaattct
      301 agtatgcttt caaggtggat agcgcaatac aagaaaaacg gctatactat tcttgagaaa
      361 agaagaggga ggccaccaaa gatgggacgt caaccaaaga agactttaga acaaatgaca
      421 gagttggagc gactccaaaa agaattagac taccttagag cggagaatgc tgtgctaaaa
      481 aagctgagag aataccggtt gagggacgaa gcaaagctca aagagcaaca gaaatcatcc
      541 aagaattaat cggtcaattt tctctagcaa ctttgcttga aatccttgat ttatcgcggt
      601 caacctatta ttatcaagtc aagcaactag ctcaagaaga taaggacatg gacttaaagg
      661 agctcattca aggcatctat gatgaacatc atggcaatta tggctatcgt cgcattcatc
      721 tggaactaag aaatcgtggt tttatcgtca atcacaaaaa agtacaacgt ttgatgactg
      781 tcatgggctt aaaagctcgt atccgtcgta agcgcaagta ttcttcttac aaaggtgagg
      841 ttggcaaaaa ggctgataat ctgattaaac gtcagtttga aggttctaag ccctacgaga
      901 agtgctatac cgatgtgacg gaatttacct tacctgaggg gaaactctat ctatcgcctg
      961 ttcttgacgg ctataacagt gagattattg atttcaccct gtctcgatcg cctgacttga
     1021 agcaagtaca aaccatgc
//
LOCUS       DARYYD010000141         1024 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.142, whole genome shotgun sequence.
ACCESSION   DARYYD010000141 DARYYD010000000
VERSION     DARYYD010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1024
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.142"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            7..>1024
                     /locus_tag="TV188_002030"
     CDS             7..>1024
                     /locus_tag="TV188_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1535319.1"
                     /translation="MSNKNWINTILDFASDCKGKLILSVVMASIGVFFSIIPYWSVYK
                     LMAVFIEQKATGEDVLYYGAIGIIAYFIRYICHGVSTILSHISAYTILRNIRENLGEK
                     LLSISMGNASKKTIGEYKSIIVDKVETIEMPLAHIIPECVAALLLSLGIAIFMVFISW
                     EMALAMFITVPFALMAYKKLMGNFNQLYEAQMKSNKYMNSTIVEYISGIEVIKTFNQD
                     SNSYKKYKDAVNLYKDHTLNWFKSTWSIMNFASSILPSTFLGTLPVGMILYLNGTLTP
                     AEFCICLMLSLGIVIPLTQFTNYVNLLKSIEYAVKDINEILCIPNLISIDNNEHICTT
                     NIKFN"
BASE COUNT          367 a          128 c          171 g          358 t
ORIGIN      
        1 agttacatga gcaacaaaaa ctggataaat actatattag attttgcttc agattgtaaa
       61 ggaaagttga ttttatcagt agttatggct agtataggag tgttctttag cattatacct
      121 tattggtcag tatataaact tatggcagtc tttatagaac aaaaagcaac tggagaagat
      181 gtattgtatt atggagcgat tggtattatt gcatatttta tcagatatat ttgccatgga
      241 gtatcaacaa tattatctca tatatccgct tacacaatct taagaaatat aagagaaaat
      301 ttaggtgaaa aattgctcag tatttctatg ggaaatgcgt caaaaaagac aataggagaa
      361 tataagtcaa ttattgtaga caaagttgaa acaattgaga tgcctctagc acatatcata
      421 ccagagtgtg ttgctgcatt gcttttatca ctaggtattg caatatttat ggtcttcata
      481 agttgggaga tggctcttgc gatgtttatt acagtgcctt ttgctttgat ggcatataaa
      541 aaactaatgg gtaattttaa tcagctttat gaagctcaaa tgaaatctaa caagtatatg
      601 aattctacaa tagtagaata tattagtggt atagaagtta taaaaacttt taatcaggat
      661 agtaattcat ataaaaaata taaagatgca gtaaatttat acaaagatca tacattgaat
      721 tggtttaaat caacttggag tattatgaat tttgcaagtt ctattttgcc atcaacattt
      781 ttgggaacat tacctgtggg tatgattcta tatttaaacg gaacactgac acctgctgaa
      841 ttttgcatat gtctaatgct ttctcttgga atagtaattc ctctcactca atttacaaat
      901 tatgtcaatc tgttaaaaag tatagagtac gctgtaaaag atataaatga gattctatgt
      961 attcctaatc ttatttctat cgataataat gaacatattt gtacaacaaa tataaagttt
     1021 aata
//
LOCUS       DARYYD010000142          958 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.143, whole genome shotgun sequence.
ACCESSION   DARYYD010000142 DARYYD010000000
VERSION     DARYYD010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..958
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.143"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..>958
                     /locus_tag="TV188_002031"
     CDS             <1..>958
                     /locus_tag="TV188_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1535320.1"
                     /translation="QDNQKVRLASNCLGTTRFNQVMIERGDKATDYVAPVVVEGSGES
                     TGVFKSLEEMLSGLQSINLELTDTKNSNLWSKIKLTTNGMLREYHRDHIKTEIVESAD
                     GIAKRIADDTGQKLALINETIKGIKREYQDADRQLSASYQAGIDGLKTQLANDKIGLQ
                     AEIKLSAQGLSQKYDDELRKLYAKITTTSSGTTEAYENKLEGLRAEFTRSNQGMRTEL
                     ESQISGLRSVQQSTAKQISQEIRDRTGAVSRVQQDLASYQRRLQDAEKNYSSLTQTVK
                     GLQSTVSDPSGKIQSRFTQLQNQIDQRVTRDDVMSIINLSGD"
BASE COUNT          308 a          207 c          236 g          207 t
ORIGIN      
        1 gtcaagacaa tcaaaaagtc agattagcca gcaactgtct aggaacaact cgctttaatc
       61 aggttatgat tgagagaggc gacaaagcga ctgactatgt tgcgcctgtt gtcgttgagg
      121 gcagcggtga gtcgacaggt gtgtttaaaa gtcttgagga gatgcttagt ggtctacagt
      181 ctattaattt agagctgaca gataccaaaa actccaatct ttggtcaaaa atcaagctca
      241 cgacaaacgg tatgttacgc gagtatcatc gtgatcatat taaaacagag attgttgaga
      301 gcgcagatgg tattgccaag cggattgccg atgacactgg ccaaaagctg gcactaatca
      361 atgagaccat caaaggtatc aagcgtgagt accaagacgc agatagacag ctatccgcga
      421 gctaccaagc gggcattgat ggcctaaaaa ctcaactggc caatgacaaa atcggtctac
      481 aagctgagat taagctgtca gctcaaggct tgtcgcaaaa gtacgacgat gagctgcgca
      541 agctgtatgc taagattacc accacctcat caggcacgac cgaagcgtac gaaaacaagc
      601 ttgagggctt gcgtgctgag tttacccgta gcaaccaagg catgcgcact gagttagagt
      661 cgcagattag cgggttaagg tctgtgcagc agtcaactgc aaaacaaatc tcgcaggaga
      721 ttagagacag gacaggtgct gttagtcgtg tgcaacagga cttagccagc tatcaaagac
      781 gcttgcagga cgccgaaaaa aattacagca gtttaaccca gacggttaaa ggtctacaat
      841 caactgttag cgatccgtca ggtaaaatcc agtcgaggtt tacacaacta caaaatcaaa
      901 tcgaccaacg tgtgacaaga gatgacgtta tgtcaatcat caacctatcc ggagatag
//
LOCUS       DARYYD010000143          891 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.144, whole genome shotgun sequence.
ACCESSION   DARYYD010000143 DARYYD010000000
VERSION     DARYYD010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..891
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.144"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(54..803)
                     /locus_tag="TV188_002032"
     CDS             complement(54..803)
                     /locus_tag="TV188_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017645388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HEL1535321.1"
                     /translation="MGMWFEYVNKEMENTKASLFVFPFAGGGVSSFRRWGNQFKDINL
                     FVAQYPGRENRFSEKAISNIEELVKGLFEDLKMTFDFNSPYYFFGHSMGTKIAYELAL
                     KIKENGLPNPNGIIISAGRAPCYKEPNPIYHLDDEGFIEGLRRYDGTPNEILDNKDLI
                     GIFLPTLRADFIIDEDYQDTKGEKLNSKILGLMGDIDEEMELEELLKWQDYTTKEFSY
                     RYINGKHMFVNTSPESVIKAIEEFVYSNENI"
BASE COUNT          277 a          185 c           97 g          332 t
ORIGIN      
        1 acctacttat atcaattaaa cttcgtagtt cttttttatc tgaaatttct attctatata
       61 ttttcattgg aataaacaaa ttcttcaatt gcttttatca cactttcagg agatgtattt
      121 acaaacatat gcttgccatt aatatatctg taagagaatt ctttcgtcgt ataatcttgc
      181 cattttaaaa gttcttcaag ttccatttct tcatcaatat cacccatcag acctaaaatc
      241 ttgctattca atttttcccc ttttgtatcc tggtagtcct catcgataat aaaatcggct
      301 cttagtgttg gtaaaaaaat cccaatcaaa tctttattgt ctaatatctc atttggagta
      361 ccatcatatc ttcttaaccc ttcaataaat ccttcatcat ctaaatgata aatcggattc
      421 ggttccttat agcaaggggc tcgcccagct gatatgataa ttccattcgg atttggtaac
      481 ccattttctt taattttcag agccaattca taagcaatct tagttcccat actatgcccg
      541 aaaaaataat aaggtgagtt aaaatcaaaa gtcattttta agtcttcaaa caatcctttt
      601 acaagttctt ctatgttgct aattgctttt tcagaaaacc tgttttctct ccctggatac
      661 tgtgcaacga agagatttat atctttaaat tgattacccc atcttctgaa tgatgatact
      721 ccaccacctg caaatggaaa cacaaataaa ctagctttcg tgttttccat ttctttatta
      781 acgtattcga accacattcc catcaaaaca ccttccatct gattattaat atactactag
      841 aactattatt gttagataca tctaacaata atagtttaat ccttctaaca t
//
LOCUS       DARYYD010000144          853 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.146, whole genome shotgun sequence.
ACCESSION   DARYYD010000144 DARYYD010000000
VERSION     DARYYD010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..853
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.146"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..472
                     /locus_tag="TV188_002033"
     CDS             <1..472
                     /locus_tag="TV188_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009429246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1535322.1"
                     /translation="DTIENNIKFGNPNVSKEEIINAAKKSHCHEFIMNLPNGYETIVG
                     EGGDFLSGGEKQRISIARAMLKDAPIIILDEATSSIDPENEYLIQRAISNLSKGKTVI
                     IIAHRIVTIEEADQIIVLKEGEIAQIGKHTELMSQDGLYRDYMRIRGKTEDWKI"
     gene            492..>853
                     /locus_tag="TV188_002034"
     CDS             492..>853
                     /locus_tag="TV188_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase NADP-binding
                     domain-containing protein"
                     /protein_id="HEL1535323.1"
                     /translation="MYNIGVLGCNGNIGSLFMEKVSKWEDNYIYAVSRSHMNFIKKDN
                     IEYIFFDAENIEKLDKFCSKCDVIVNCTGIDKTNIMNICLKNDVNYVDPSFVDTDIMS
                     KKLMETNDNCIICSAGCNP"
BASE COUNT          339 a           81 c          173 g          260 t
ORIGIN      
        1 tgatacaatc gaaaacaata taaaatttgg taatccgaat gtaagtaagg aagaaataat
       61 aaatgcagcg aagaagtcac attgtcatga atttataatg aatttgccaa atggatatga
      121 aactattgtt ggtgaaggtg gtgatttttt atctggtgga gaaaaacaaa gaatatctat
      181 agcaagggca atgctaaaag atgctccaat tattattttg gatgaagcaa catcaagcat
      241 agatcctgaa aacgaatatt taattcaaag agcaatatcg aatttgagta aaggtaagac
      301 tgtaattatt attgctcata gaattgtaac aattgaagaa gcagatcaga taattgtttt
      361 gaaagaagga gagattgctc aaataggaaa gcatacagaa ctgatgagcc aagatggtct
      421 gtatagagat tatatgagaa tcaggggtaa aacagaggac tggaaaatat aatatagata
      481 ggaggaggtt tatgtataat ataggagttt taggttgcaa tggtaatata ggttcgcttt
      541 ttatggaaaa agtgtctaaa tgggaagata attatattta tgctgtatcg agaagtcata
      601 tgaattttat taagaaagat aacatagaat acatattttt tgatgcagag aacatagaaa
      661 aattagacaa attctgttct aaatgcgatg tgattgtaaa ttgtactgga atagataaaa
      721 ctaatattat gaatatatgt ttaaaaaatg atgttaatta cgtagatcca tcttttgttg
      781 acacagatat tatgtctaaa aaacttatgg aaacaaatga taactgtata atttgttcgg
      841 caggttgcaa tcc
//
LOCUS       DARYYD010000145          841 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.147, whole genome shotgun sequence.
ACCESSION   DARYYD010000145 DARYYD010000000
VERSION     DARYYD010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..841
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.147"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            101..>841
                     /locus_tag="TV188_002035"
     CDS             101..>841
                     /locus_tag="TV188_002035"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1535324.1"
                     /translation="MITKKQRKLKRHTTIRRLCHQALAATLITGSLMGTGLLGNKVVY
                     GDMKSDAKKVLATLQKGNHKQELKKVLRTIGDDSLLLLWLLVSGDSNLDESNKSFDYL
                     SIWNTGSRVGKVISPTEYFKQESKNTENRQAVYSEFKQRVEERSKKAKEATEALNQKA
                     QLEATVKNINEELEKTREGFKVVSENSNKLEKQLMAEKIKTRTAEETAKQAKTDKEKA
                     EAEAKKAKEEAKTAEGKVKQAETEKRNAE"
BASE COUNT          364 a          126 c          165 g          186 t
ORIGIN      
        1 gatgagcttt gtcgtttctc acttccaacc gccatgttaa aatcttctct gagaaagaat
       61 gttataaaaa ataatcattc tatcaccaaa ggagagaaaa atgataacta aaaaacagag
      121 aaaactaaaa agacacacaa caatcagacg cctgtgtcat caagccctag cagctaccct
      181 catcacagga agcctgatgg gaacaggact acttggaaat aaagtcgtgt atggggatat
      241 gaaaagcgat gccaaaaagg tattagcaac attgcaaaaa ggtaatcata aacaagagtt
      301 aaaaaaagtt cttagaacta ttggtgatga tagtttgcta ttattatggt tacttgtatc
      361 gggtgattcc aatttagatg aaagtaataa aagttttgat tatttatcaa tttggaatac
      421 tggatctaga gttggtaaag tgatatctcc tactgaatac tttaaacaag aatcaaaaaa
      481 cactgaaaat aggcaagctg tttatagtga atttaaacaa cgcgtagaag aacgatctaa
      541 aaaagccaag gaagccactg aagcactaaa ccaaaaagct caattggagg ctacagttaa
      601 aaatataaac gaagaacttg aaaaaactag agaaggtttt aaagttgtga gtgaaaactc
      661 aaacaaatta gaaaaacaat taatggctga gaaaataaaa acacgtacag ctgaagaaac
      721 tgccaaacaa gctaaaaccg ataaagaaaa agcagaggct gaagctaaaa aagcgaaaga
      781 ggaagctaag actgcggaag gaaaagttaa acaagcagaa actgagaaaa ggaatgcgga
      841 a
//
LOCUS       DARYYD010000146          804 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.148, whole genome shotgun sequence.
ACCESSION   DARYYD010000146 DARYYD010000000
VERSION     DARYYD010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..804
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.148"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            84..743
                     /locus_tag="TV188_002036"
                     /pseudo
     CDS             84..743
                     /locus_tag="TV188_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003037566.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
     gene            734..804
                     /locus_tag="TV188_002037"
                     /pseudo
     CDS             734..804
                     /locus_tag="TV188_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          324 a          115 c          174 g          191 t
ORIGIN      
        1 ataaatttaa ggtataatat aaggtattaa aaagggaaaa gacctgttta acaggataag
       61 atataaaaga ggcaggtgtc agaatggacg aaataaaatt gtatgaaaat aaagagatac
      121 gctccatttg ggacgaagaa aaagaagagt ggtatttttc agtagtcgat gtagttggag
      181 ttttgacaga acaagaaaac gtaagaggtg ctagtaccta ttgggctgta ctaaaaaaga
      241 gattaaaaga agaaggaaat gaactgctta caatttgtaa gcagttgaaa atgaaagcaa
      301 cagatggaaa aatgcgttta actgatgtag cagatatgca aggaatattc cgtattatcc
      361 agtccatccc atcccctaaa gcagaacctt ttaagttatg gcttgctgag gttggaaaag
      421 aacgaattga tgaaattatc gatcctgaac ttacgattga cagagcctta gaaacttatc
      481 taaagaaggg atatacacgt gagtggataa atcaaagact tcaagccatt caggtaagaa
      541 aagaactgac tgatgcttgg gatgaccatg ggatacaaaa aggcaaagaa tacgcaattc
      601 ttactgatga aatcaccaaa gcatggtccg gaatgacaac aagaggttat aaaaatctga
      661 agggtttgaa aaaggaaaat ctaagggata atatgaccac tcttgaaata gttcttaata
      721 tgcttgcaga agccacaaca acaaacgcat taaagcaaag ctaaaaggac ttagccctgt
      781 gcaatacaga actaaatcct ttca
//
LOCUS       DARYYD010000147          789 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.149, whole genome shotgun sequence.
ACCESSION   DARYYD010000147 DARYYD010000000
VERSION     DARYYD010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.149"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..420)
                     /gene="spek"
                     /locus_tag="TV188_002038"
     CDS             complement(<1..420)
                     /gene="spek"
                     /locus_tag="TV188_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptococcal pyrogenic exotoxin SpeK"
                     /protein_id="HEL1535325.1"
                     /translation="MRRKNEKNTLALLFLVCVSLTLCTTESVFSDTYNTNDVRNPRNI
                     YAPRYDKDEILDNRRLKEIYNKEIIEKNNISINAKQGTQLIFNTDENTTVWNDNTFKK
                     VISSNLSPSQERMFNVGDHVNIFAIVKSYHVVCKEQFN"
     gene            complement(532..>789)
                     /locus_tag="TV188_002039"
     CDS             complement(532..>789)
                     /locus_tag="TV188_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HEL1535326.1"
                     /translation="SKSGTFTLDAAEINVRRWPNLTSEVVDSYKQGQTVSFDSEGYAN
                     GYYWISYVGGSGKRNYMAIGPTDKDGNIISLWGKLGGKDPR"
BASE COUNT          246 a          152 c          108 g          283 t
ORIGIN      
        1 attgaattgt tccttgcata caacatgata tgactttact atagcaaaaa tattcacatg
       61 atcaccaaca ttaaacattc tttcctgtga aggagaaaga ttactagata tgactttctt
      121 aaaagtgtta tcattccaaa ctgtagtatt ttcatccgta ttaaaaatca attgcgttcc
      181 ttgtttggca tttatcgata tattattttt ttcaataatt tctttattat atatttcttt
      241 taatcttcta ttatctaaaa tttcgtcttt atcatatcta ggagcatata tgttccttgg
      301 atttctaaca tcatttgtat tgtacgtatc tgaaaagaca ctctcagtag tgcatagggt
      361 aagcgataca cacacaagga atagcaaagc caaggtattt ttttcatttt ttctcctaat
      421 attttttaaa tttaatcaat ttacttagca agtatactat atttaaataa taattcaact
      481 ataatttaaa aaaaacaaaa aaccgccctc aatcaagaga gcggttttgt cttatctcgg
      541 atctttacct cctaatttac cccaaagact gataatattc ccgtctttgt cagtaggacc
      601 aattgccata taattacgct tacctgagcc tccgacatag ctaatccagt agtagccatt
      661 ggcgtaaccc tcactatcaa agctaacggt ttggccttgc ttataactat ctactacctc
      721 actggttaaa ttcggccagc ggcggacgtt gatctctgcg gcgtcaagtg taaaagtacc
      781 tgattttga
//
LOCUS       DARYYD010000148          724 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.150, whole genome shotgun sequence.
ACCESSION   DARYYD010000148 DARYYD010000000
VERSION     DARYYD010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..724
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.150"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            61..>724
                     /locus_tag="TV188_002040"
     CDS             61..>724
                     /locus_tag="TV188_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HEL1535327.1"
                     /translation="MTTKEKQTKLMRRYGIFSVVVALTALAGLGAANEVKATAKKSLN
                     ELPNPVEIIQYNSTRTTDREARKYLNQLYEFLKPYLGSLEEEAQKGGPQGPVGPAGPR
                     GERGEPGPKGDRGPEGQRGEQGPAGPIGPQGPRGDKGETGEIGPRGEQGPTGPTGKPG
                     ERGPKGDRGERGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGEKGEQGQRGE
                     KGE"
BASE COUNT          256 a          135 c          208 g          125 t
ORIGIN      
        1 aaatcttctt tgggagaaaa tttagaaaaa aataatattt ctatcactaa ggagagaaag
       61 atgacaacta aagaaaaaca aacaaaacta atgcgcaggt atggcatttt ctcggtagtc
      121 gttgccctaa cagctctagc aggtctagga gcagctaatg aagttaaggc aactgctaaa
      181 aaatctttaa atgagttacc taatccagta gaaattattc aatataattc aacaagaact
      241 actgatagag aagctagaaa gtatcttaat caattatatg agtttttgaa accttattta
      301 ggaagtttag aagaagaagc tcaaaaagga gggccacaag gacctgtggg acctgctggt
      361 cctagaggtg aacgcggaga accaggacct aaaggagacc gaggtcctga gggccaaaga
      421 ggtgagcaag gcccagcggg gcctattgga ccccaagggc ctcgtggtga caagggtgaa
      481 actggagaaa ttggacctag gggagaacaa ggtccgaccg gtcctactgg taagccagga
      541 gagcgtggcc ctaagggtga cagaggcgaa cgcggcgaaa aaggcgagca aggccagcgt
      601 ggcgaaaaag gcgagcaagg ccaacgtggc gaaaaaggtg aacaaggcca acgcggtgaa
      661 aagggcgagc aaggccaacg tggcgaaaaa ggtgaacaag gccaacgcgg tgaaaagggc
      721 gagc
//
LOCUS       DARYYD010000149          700 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.151, whole genome shotgun sequence.
ACCESSION   DARYYD010000149 DARYYD010000000
VERSION     DARYYD010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 700)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 700)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..700
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.151"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            <1..>700
                     /locus_tag="TV188_002041"
     CDS             <1..>700
                     /locus_tag="TV188_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011527920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEL1535328.1"
                     /translation="SVVGETDYKKACHAIKAAGYATASDYAELLIQLIEENNLQKWDK
                     EALKTNKEVTMTTANEIVQYCVDLANSGMGVDKDGCFGTQCADLPCFIVKNWFGIDLW
                     GNAIDLLNSAAAQGLEVIYNAPGVNPKASDLFVMEVAGSPYGHTGAVIEDSDGYTIKT
                     VEQNIDGNWDSLQVGGPARFNTRDFTGVVGWIRLPVDHTNQTVDTAPQTSDTIVETSK
                     TGTFTLDAAEINVRR"
BASE COUNT          204 a          138 c          182 g          176 t
ORIGIN      
        1 atcagttgtc ggggagactg actataaaaa ggcttgtcat gcaataaaag cagccggtta
       61 tgccactgca agtgattatg cggagctgct tatccagttg attgaggaaa acaacttgca
      121 aaaatgggat aaggaagcct taaaaactaa taaggaggta acgatgacaa ccgcaaatga
      181 gattgtacaa tactgtgttg accttgccaa ctcaggtatg ggagttgata aagatggctg
      241 ttttgggacg cagtgtgcgg acttgccatg ttttatcgtc aaaaactggt tcgggattga
      301 cttatggggg aatgcgattg acctgttaaa cagtgcagca gcgcaaggtc tagaggttat
      361 ctataacgca cctggagtta atccaaaagc tagtgactta tttgtcatgg aggtagctgg
      421 cagtccttat ggacacacag gagctgttat tgaggacagt gatggctata ccattaaaac
      481 tgttgagcaa aacattgacg gcaactggga cagtttacaa gtaggtggcc ctgctcgctt
      541 taatactcgt gactttactg gcgttgtcgg ctggattagg ttacctgttg accatactaa
      601 ccagacagta gatacagcac cgcaaacgtc tgacaccatc gtggagacgt caaaaacggg
      661 tacttttaca cttgacgccg cagagatcaa cgtccgccgc
//
LOCUS       DARYYD010000150          671 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.152, whole genome shotgun sequence.
ACCESSION   DARYYD010000150 DARYYD010000000
VERSION     DARYYD010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..671
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.152"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..>671)
                     /locus_tag="TV188_002042"
     CDS             complement(<1..>671)
                     /locus_tag="TV188_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="HEL1535329.1"
                     /translation="REIETLKDIWKEIFGYDTKYRTSFFSNGGDSLIATKLSAKIEEK
                     FKISFSIKDVMENITIEAQAQVIKDRIAEQRFADKISVIEETITEEEFDLTDVQHAYY
                     VGRNKDMILGGVSTHCYFEIESSDIDVNKLEKAWNYLIKIHPMLRAIITENGKQKILQ
                     EVEYYKIMTSADSELIIRDIMSQQVLNLDKWPIFDIRISKREDKADIIHISFDNIILD
                     GWSMF"
BASE COUNT          203 a          140 c           65 g          263 t
ORIGIN      
        1 aaaaacatac tccatccatc caatattata ttatcaaaac taatatgaat tatatccgct
       61 ttatcctcac gcttgctaat tcttatgtca aatataggcc atttatccag attaagcacc
      121 tgttgtgaca taatgtcacg gataatgagt tctgaatctg cactagtcat tattttataa
      181 tattctacct cttgcagtat cttctgctta ccattttcag ttataattgc tcgtaacatc
      241 ggatgaattt ttattaaata attccacgct ttctccaact tatttacatc tatatcactt
      301 gattctattt caaaataaca atgagtagaa actcctccta aaatcatatc cttgtttctt
      361 ccaacataat aagcatgttg aacatccgtc aaatcaaact cttcctctgt aatagtttcc
      421 tctatcacgc taattttatc cgcaaaacgc tgctcagcaa ttctatcttt aatcacttgg
      481 gcttgtgctt caatagtaat attttccatt acatctttta tactaaaact tattttgaat
      541 ttttcctcta ttttagctga tagttttgtt gcaattagag aatctccacc atttgaaaaa
      601 aagctagttc tatactttgt atcatatcca aatatttctt tccatatatc ctttaaagtt
      661 tctatttctc t
//
LOCUS       DARYYD010000151          669 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.153, whole genome shotgun sequence.
ACCESSION   DARYYD010000151 DARYYD010000000
VERSION     DARYYD010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..669
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.153"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            79..462
                     /locus_tag="TV188_002043"
     CDS             79..462
                     /locus_tag="TV188_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEL1535330.1"
                     /translation="MKKALSLVLLTGLMLASSVPAFAAEETNLPYVEGLGYEVEVFEE
                     DYTQPKLFSYDSGWKSFLGGKWRHGVGSRYVWSKYDHNNKTHKTTVQGAGGQFSYSGW
                     TSAGSRAEASWEKALSGNRAWADVK"
BASE COUNT          229 a           73 c          154 g          213 t
ORIGIN      
        1 tgagtagagt tttgggaaac tttattcgga agaaaaattt tacaaaaaat ttaagtattt
       61 gagagaggag aatttatcat gaaaaaagca ttgtcattag tattattaac aggtttgatg
      121 ttagcatcat ctgtaccagc atttgcagca gaagaaacaa acttgccata tgttgaaggt
      181 cttggttatg aggtggaagt atttgaagaa gattatactc agccaaagtt gttcagttat
      241 gatagcggat ggaaaagttt tttaggtgga aaatggagac atggtgtagg tagtcgatat
      301 gtttggtcta aatacgatca caataataaa acacataaaa ctacagtaca aggtgctggt
      361 ggtcaattct cttattcggg ttggacaagc gctggaagta gagcagaagc ttcttgggaa
      421 aaagctttaa gtggtaatag ggcttgggct gatgttaaat aacaataaat aaaaaatagt
      481 tgaacgagtt tgagcggtgc cacgttgtta ttttagcatt gtggcattac tcatactcgc
      541 tatttttata aagttggaga tgatacagaa tgaaaaaaac agtgggtata ttggcaattt
      601 tactaattat agtgattggt ataggaaagt ttttctattc agacggcatg tttttaaata
      661 tattcataa
//
LOCUS       DARYYD010000152          623 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.154, whole genome shotgun sequence.
ACCESSION   DARYYD010000152 DARYYD010000000
VERSION     DARYYD010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..623
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.154"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            106..>623
                     /locus_tag="TV188_002044"
     CDS             106..>623
                     /locus_tag="TV188_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002922687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEL1535331.1"
                     /translation="MAIEVLNVTKKFGSKKIFTDLNLTFEAGKSYALIGGSGSGKSTL
                     LNIIGRLEKIDSGKVLVDEQDIWKTKERTFFKTIIGYVFQNYSLIENKTVYDNLRLIN
                     KDKKIIADVLEKVGLSNDYLNQKIYELSGGQVQRVAIARMLMKPRKIILADEPTGALD
                     SEIGKEIINLLL"
BASE COUNT          245 a           66 c          116 g          196 t
ORIGIN      
        1 attatatatt ggcattgctt ctttaatggt tttaattttt tcaacaataa tgagttttag
       61 aaaattatct gaaaaatata cacaaattct aaaaggagat gactaatggc aattgaagtt
      121 ttgaatgtta ccaaaaaatt cggctcaaaa aagatattca cagatttaaa tttaacgttt
      181 gaagctggaa aaagctacgc attgattgga ggctctggtt caggtaaaag tacactactt
      241 aatatcatag gaagactaga aaaaattgac agtggaaagg ttttagttga tgagcaggat
      301 atttggaaga caaaagaaag aactttcttt aaaactatta ttgggtatgt attccagaat
      361 tattctttaa tagaaaacaa aacagtatat gataatttga gactcatcaa taaagataaa
      421 aaaataatag ctgatgtact tgaaaaagta ggactttcta atgactattt aaatcagaaa
      481 atatatgaat tatctggagg acaggttcag cgtgtagcta ttgcaagaat gttaatgaag
      541 ccacgtaaaa ttattttagc ggatgaacct acaggagctt tggatagtga gattggaaaa
      601 gaaatcatta atttattgtt gag
//
LOCUS       DARYYD010000153          576 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.155, whole genome shotgun sequence.
ACCESSION   DARYYD010000153 DARYYD010000000
VERSION     DARYYD010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..576
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.155"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            42..>576
                     /locus_tag="TV188_002045"
     CDS             42..>576
                     /locus_tag="TV188_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012678941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEL1535332.1"
                     /translation="MISVKKNLCRLGVLSSSLLLLTAATTPSVIAFADIQTSAIKNNT
                     DDADGMYFVQSYEMSVEDKELLVRNVKANHPTVSEDFIREVIERQLVGDYTLPEEETL
                     FRSAWQGVTVDQLGAALDVAIGMALTGGAGSIAAGVLRVGKREAVGRVKSILIKYGLG
                     KMIAEIPVDYMLNLLSPG"
BASE COUNT          186 a           76 c          128 g          186 t
ORIGIN      
        1 gtctaaacat ttatttttaa agaagggcat ggtgaatcaa tatgatttct gtaaagaaaa
       61 atttatgtcg cttaggtgtt ttgtctagta gtttattact tttaacagct gcaacgactc
      121 catctgtcat tgcttttgcg gatattcaaa caagtgccat aaaaaataat acagatgacg
      181 cagatggtat gtattttgtt caaagttatg aaatgtctgt agaagataaa gaattgcttg
      241 ttcgaaatgt taaagcaaat catcctacag tttctgaaga ttttatcaga gaagttattg
      301 aaagacaatt agtaggtgat tatacattac ctgaagaaga gactcttttc cgctcagcat
      361 ggcaaggggt tacagtagat caattgggag cagctctaga tgtggctatt ggtatggcat
      421 taacaggtgg agctggatca attgctgctg gtgttttgag agtcggaaaa agagaagctg
      481 ttggtcgggt aaaatcaatt ctaattaaat atgggctagg taaaatgata gctgaaattc
      541 cagtcgatta catgttaaat ttattatcgc caggat
//
LOCUS       DARYYD010000154          575 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.156, whole genome shotgun sequence.
ACCESSION   DARYYD010000154 DARYYD010000000
VERSION     DARYYD010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..575
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.156"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..>575)
                     /locus_tag="TV188_002046"
     CDS             complement(<1..>575)
                     /locus_tag="TV188_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015898603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronidase"
                     /protein_id="HEL1535333.1"
                     /translation="AGGIDAKMSAKEIISAINLNGYGVRISGERIALDGNTTVNGAFG
                     AKLGEFIKLKADQIIGGTIDAAKIRVINLNASSIVGLDANFIRAKIEHTITSLLEGKV
                     IRARNGAMMIDLNSAKMDFNSNATINFNNKDNALVRKDGTHTAFVHFSNATPKNYTGS
                     ALYASIGITSSGDGINSASSGRFCGARFFRYA"
BASE COUNT          159 a          148 c          110 g          158 t
ORIGIN      
        1 gcatacctaa aaaacctagc accgcaaaaa cgaccgctcg acgcgctgtt aatcccgtca
       61 cctgacgagg ttatcccgat cgaggcgtaa agcgcactac ctgtataatt ttttggcgtg
      121 gcattgctaa aatgcacaaa ggctgtgtgg gtaccgtctt tacgtacaag cgcattgtcc
      181 ttgttgttaa agttaatggt agcattgcta ttaaaatcca ttttagccga gtttaaatca
      241 atcatcatcg ctccgttgcg agctctgata actttaccct caagcaaact tgtaatcgta
      301 tgttcaattt tagccctgat aaagttagca tctaagccga caatgctgct agcgttaaga
      361 ttgatcactc taatcttagc agcgtcaatc gtaccaccaa tgatttgatc agctttgagc
      421 ttaataaact caccgagctt agccccaaat gccccattga cggtcgtatt accgtccaga
      481 gcaatacgct cgccagagat ccgcacgcca tagccattaa gatttatcgc tgagataatc
      541 tctttagcgc tcatcttagc gtcaatacca ccggc
//
LOCUS       DARYYD010000155          546 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.157, whole genome shotgun sequence.
ACCESSION   DARYYD010000155 DARYYD010000000
VERSION     DARYYD010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..546
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.157"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            11..>546
                     /locus_tag="TV188_002047"
     CDS             11..>546
                     /locus_tag="TV188_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HEL1535334.1"
                     /translation="MFIIKGEVSRKDLIREIEKAIKSDELGAFIGAGLSIPAGFCSWK
                     ELLREPAEEIGLDVEKESDLVNLAQYYSNSKKRTSIDDLIKGQFSQLVKPTENHKLLS
                     QLPISTFWTTNYDKLIEKALENNMKKPYVKTKDEQLRGTNHNFDAIVYKLHGDVETPE
                     DAVITRSDYEEFGYNKRK"
BASE COUNT          222 a           58 c          110 g          156 t
ORIGIN      
        1 aagggaggag gtgtttatta ttaaaggtga agtatccaga aaagatttga ttagagaaat
       61 tgaaaaagct attaaaagtg atgaattagg agcatttatt ggagcaggat tatcaattcc
      121 tgccggattt tgtagttgga aagaacttct aagagaacct gcagaagaaa ttggattaga
      181 tgttgaaaaa gaaagtgatt tggttaactt ggctcagtat tattctaatt caaaaaagag
      241 aacatcaata gatgacttga tcaaaggtca attttctcaa ttagtaaagc ctactgaaaa
      301 tcataaatta ttgtcgcagc tgcccatttc aactttttgg acaacaaatt atgataagtt
      361 aatagaaaaa gctttagaaa ataatatgaa aaagccttat gtaaaaacaa aggatgaaca
      421 attaagaggt acaaatcata attttgatgc gatagtatat aagctgcatg gtgatgtaga
      481 aactcccgaa gatgcagtaa taacaagaag tgattatgaa gagtttggat ataacaaaag
      541 aaaatt
//
LOCUS       DARYYD010000156          495 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.denovo.158, whole genome shotgun sequence.
ACCESSION   DARYYD010000156 DARYYD010000000
VERSION     DARYYD010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..495
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.denovo.158"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            complement(<1..>495)
                     /locus_tag="TV188_002048"
     CDS             complement(<1..>495)
                     /locus_tag="TV188_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEL1535335.1"
                     /translation="FNKHIYDKLYDYDTFTEVHYGGASSGKSHGVIQKVVLKACQDWK
                     HPRKVLFLRKVGATVYDSIFEDVKQCLELWGLLDKCKVNNSAYRIELPNGATFIFKGL
                     DNPEKIKSIKGVSDVVMEEASEFTLDDYTQLTLRLRDRKHLKKQIFLMFNPVSKVNWV
                     YKAFF"
BASE COUNT          153 a          104 c           78 g          160 t
ORIGIN      
        1 gaagaaggct ttataaaccc agtttacttt tgataccggg ttaaacatta aaaaaatttg
       61 tttctttaaa tgtttacgat cacgcagacg aagagttagc tgagtataat catcaagcgt
      121 aaactcgcta gcctcttcca taacgacatc tgacacgcct ttaattgact tgattttctc
      181 agggttgtct aggcctttaa aaataaatgt cgccccattt ggcagctcaa tcctatatgc
      241 tgaattatta accttacact tgtctagtag accccataac tcaagacact gtttcacatc
      301 ttcgaatatt gagtcataaa cagttgcacc aactttgcgt aaaaaaagca cctttctagg
      361 gtgcttccag tcttggcatg cttttaatac tactttttga ataactccat gagatttacc
      421 agacgatgct ccgccgtaat ggacctctgt aaaagtgtca tagtcatata atttatcata
      481 aatatgctta ttaaa
//
LOCUS       DARYYD010000157        16664 bp    DNA     linear   BCT 04-DEC-2023
DEFINITION  TPA_asm: Streptococcus equi subsp. equi isolate Culture
            SAMN26611961-rid16723963.guided.042, whole genome shotgun sequence.
ACCESSION   DARYYD010000157 DARYYD010000000
VERSION     DARYYD010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN26611961
            Sequence Read Archive: SRR18311079
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus equi subsp. equi
  ORGANISM  Streptococcus equi subsp. equi
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001574808.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001574808.1
            Genome Coverage       :: 87x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/13/2023 00:13:35
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,060
            CDSs (total)                      :: 2,021
            Genes (coding)                    :: 1,937
            CDSs (with protein)               :: 1,937
            Genes (RNA)                       :: 39
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            partial rRNAs                     :: 1 (5S)
            tRNAs                             :: 32
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 84
            CDSs (without protein)            :: 84
            Pseudo Genes (ambiguous residues) :: 0 of 84
            Pseudo Genes (frameshifted)       :: 35 of 84
            Pseudo Genes (incomplete)         :: 31 of 84
            Pseudo Genes (internal stop)      :: 27 of 84
            Pseudo Genes (multiple problems)  :: 9 of 84
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16664
                     /organism="Streptococcus equi subsp. equi"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN26611961-rid16723963.guided.042"
                     /isolate="Culture"
                     /host="horse"
                     /sub_species="equi"
                     /db_xref="taxon:148942"
                     /country="USA: WA"
                     /collection_date="2020-08-19"
                     /collected_by="Washington State University Animal Disease
                     Diagnostic Laboratory, Pullman, WA"
     gene            215..595
                     /locus_tag="TV188_002049"
     CDS             215..595
                     /locus_tag="TV188_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEL1535336.1"
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLINKDV
                     ENKETAIVSVLQFVIVKEEFVISGVISQMVRILGRLVDKPSEFTQEEVESLAAPLLDM
                     VKRLTYEVTEIALDRPGINLEFKS"
     gene            595..1443
                     /locus_tag="TV188_002050"
     CDS             595..1443
                     /locus_tag="TV188_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEL1535337.1"
                     /translation="MKLAIITDNTAHLPEQLAEHADIFVLDIPVIIDGQSYVEGQNLT
                     IEAFYQSMRESQELPKTSQPSLSELDDLLGRLSTEHYTHVIGLFLASGISGFWQNIQF
                     LIEEHPELTIAFPDSKITSAPLGSMVRNALEWSQQGLSFAEIMDKLEEQIAGTTAFIM
                     VDDLNHLVKGGRLSNGSALLGNLLSIKPILRFDSEGKIVVYEKVRTEKKAMKRLVDIL
                     KELTASGQYEVSIIHARAQDKADILKQLLLDNGYTCPVEEVHFGAVIAAHLGEGAVAF
                     GITPLV"
     gene            1543..2754
                     /locus_tag="TV188_002051"
     CDS             1543..2754
                     /locus_tag="TV188_002051"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEL1535338.1"
                     /translation="MTLMTMPSEFQKALPIVKKIKQAGFEAYFVGGSVRDSLLNRPIH
                     DVDIAASCYPEETKAIFLRTIDVGIEHGTVLVLENGSEYEITTFRTEDVYVDYRRPSQ
                     VSFVRSLEEDLKRRDFTVNALALDEDGQVIDIFNGLEDLKHKLLRAVGRPQERFEEDA
                     LRIMRGFRFAASLDFDIEAETFEAMKSHAPLLEKISIERSFIELDKLLMAPKWRKGIL
                     AMVACQAFNYLPGLVGKEEALQKYLKTLAADYVFQDNHQAWAYLLVMLELDQPKAFLK
                     AWKTSNDFQRRVTMMASLYQIRQERQLEKWDIYSFGKDLALLVDDLRQAQGLVSEAKR
                     VESLYQELTIHDKHDIVVNGSYLIRELGMKPGPQLGMLLNQIEQAIVEGRLVNQREHI
                     EAFVRRELLNE"
     gene            2747..4614
                     /locus_tag="TV188_002052"
                     /pseudo
     CDS             2747..4614
                     /locus_tag="TV188_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009854406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
     gene            4719..6464
                     /locus_tag="TV188_002053"
     CDS             4719..6464
                     /locus_tag="TV188_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1535339.1"
                     /translation="MALIWSYLKTRPKWICFDIVGGLLFVLVNLGLPTILARMIDQGV
                     MQQDQRALYFWALMMFIIVLLGVIGRVILSYASGKLTTNMIKDLRNDMYSCLQDYSHS
                     EYEKIGIASLVTRITNDAFVLMQFAEMSLRLGVVTPLMMIFSVVMIFLTSPSLAWIVA
                     VAMPFLVIVVLYVAIKTRPLSEKQQESLDRINQLVRENLTGLRVIRAFAREDFQEERF
                     NKRNDHYSGISKRLFTLTGLTEPLFVQIIIAMIVGIVWFALDPLARGQFKIGDLVAFI
                     EYSFHALFSFLMFANLFTMYPKTAVSSKRIKEVLDMPISIPKNEDGITAFTTRGYLEF
                     DNVTFAYPGETESPVLHNISFKTRPGETIAFIGSTGSGKSSLVNLIPRFYDVTLGRIL
                     VDGIDVRDYQLKALRSKIGFIPQKALLFTGTIEENLKYGKSDASHSELEQATEVSQAK
                     DFITSREKGYQTHLAEAGSNLSGGQKQRLSIARAVVKQPDIYIFDDSFSALDYKTDAE
                     LRRRLKEVTQDATVLIVAQRVGTIMDADQIIVLDQGEIVGRGTHEELLTSNAIYREIA
                     NSQLNKEDMTKEEGD"
     gene            6464..8240
                     /locus_tag="TV188_002054"
                     /pseudo
     CDS             6464..8240
                     /locus_tag="TV188_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738789.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            8381..9730
                     /gene="gdhA"
                     /locus_tag="TV188_002055"
     CDS             8381..9730
                     /gene="gdhA"
                     /locus_tag="TV188_002055"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEL1535340.1"
                     /translation="MVSAKDYVASVFDKVKRDNPHETEFLQAVKEVFDSLIPVFEKYP
                     NYIEENLLERLVEPERVISFRVPWVDDQGRVQVNRGYRVQFSSAIGPYKGGLRFHPSV
                     NQSIVKFLGFEQIFKNALTGQPIGGGKGGSNFDPKGKSDLEIMRFTQSFMTELQRHIG
                     PDLDVPAGDIGVGAREIGYLFGQYKRLNGFKNGVLTGKGLAYGGSLARTEATGYGVVY
                     FAQQMLAAKGQDLAGKTAIVSGSGNVAIYATEKLQALGVKVLAVSDSSGYVYDDKGID
                     LETLKQIKEVKRERIKTYLESHPAAVFTPAGEGSIWTIKADLAFPCATQNELQEADAK
                     ALIEHGVKAVVEGANMPSTLEAIEQFQQAGVLFGPAKAANAGGVAVSALEMAQNSGRT
                     AWTFEEVDHRLYDIMKAIYQKAAAAAKECGQEGNLVVGANIAGFLKVAQAMSAQGIV"
     gene            9862..10272
                     /locus_tag="TV188_002056"
     CDS             9862..10272
                     /locus_tag="TV188_002056"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEL1535341.1"
                     /translation="MIKKIVKDTFFLQQKAQPATKKDLWIGQDLQDTLAYYRDSCLGL
                     AANMIGENKRVIIISMGFVDLVMFNPVLIAKREAFEAEESCLSLIGQRKTKRYQEIKV
                     DYLDAHWHKKSLRLTGLPAQICQHELDHLEGILI"
     gene            complement(10463..12469)
                     /locus_tag="TV188_002057"
     CDS             complement(10463..12469)
                     /locus_tag="TV188_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HEL1535342.1"
                     /translation="MKKHFVLKSSVLGVFAGVSMLVTGVQADQVDVQFLGVNDFHGAL
                     DTTGSAYMPEGKVSNAGTAAQLAAYLDDAEADFKQTSPDGTSIRVQPGDMVGASPANS
                     GLLQDEPTVKVFNQMGFEYGTLGNHEFDEGLAEFNRIMTGTAPAEDSAINDITKQYEH
                     EASNQTLVIANVVDKETNTIPFGWKPYAVKEVPVNDKSVKVGFIGVVTTEIPNLVLKQ
                     NYEQYDYLDSAETIVKYAKELQEQQVNAIVVLAHIPATSDNGVVHDEMAAVMEKVNQL
                     YPEHSVDIVFAGHNHQYTNGTIGTTRVVQAVSQGKAYADVRGTLDTDLNDFVATPEAK
                     VIAVAPGIKTGNADIQAIVDQANDIVKTVTELKIGTAATSSTISKTENEDKESPVGNL
                     ITTAQLTIGRKTFPHVDFAMTNNGGIRADLVVKEDQTITWGAAQAVQPFGNILQVVQM
                     TGQQIYDVLNQQYDEDQKYFLQMSGLKYTYTANEANDPSTPFKVVKAYKDNGEEIDPA
                     AQYTLIINDFLYGGGDGFSVFKDAKLLGAINPDTEVFIEYIKDLEAAGKTVSAGINGV
                     KTYVTASLEGSTQSDHTGKHEIINRVFKNREGKVLATELVSDLFTPAQNANPATSIKP
                     LAAKKQANAALPATGTSQHSAAAMTILGLLTLTGTSLFKKKEGQ"
     gene            12918..14639
                     /locus_tag="TV188_002058"
     CDS             12918..14639
                     /locus_tag="TV188_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEL1535343.1"
                     /translation="MLTLIVQHIKQKKWIYILIAMTLVIYDASLVIPTRVIQDLVDLM
                     SRHQLSSGALVRHVIILLATAVVSYGVAYLWHLHLFQEAVHFKFDIQQRAFRKLVFMR
                     TPFYEKFRSGDMITRFSTDVEALMDLIGYGLMIILYAGGMIAFIIPTMFLISWKMTLI
                     GIVPILLMMVMIYGVTKKQEHLVEEAREAISSLSDEVLETVEGIRVMRAYSKKDYLAL
                     HFAQKTQNLADKWNQVAKYRALYFPLYSVMIAISTVIILMVGLQLIASSEVTLGQVIA
                     LQLYLVSLVEPFGMLSDFILVYQTGKTSFGKINELIETSDDMEPDGQLELESFDQIAF
                     IDYSFTYANSSRPSLEKINLTLKKGQTLGIVGKTGSGKTTLVRQFLRQYPLGQGQLMI
                     NHRSVLDYKRQSLERQIGYVPQEHILFSKTVAQNIAMGKKAATTEEILEAIETAAFTR
                     DVQGMAKGLDTEIGERGLSISGGQKQRISIARAFLSQPDLLILDDSLSAVDARTETDI
                     IRHIQDERKGKTTLIVSHRLSAIQHADWVIVLDQGQIVEEGQPQQLLAQKGWYYEQYQ
                     RQQAQEV"
     gene            14641..15804
                     /locus_tag="TV188_002059"
                     /pseudo
     CDS             14641..15804
                     /locus_tag="TV188_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677880.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            15956..>16664
                     /locus_tag="TV188_002060"
     CDS             15956..>16664
                     /locus_tag="TV188_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012679638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HEL1535344.1"
                     /translation="MAEVITIANRKGGVGKTTTTLNLAYSLKELGKKVLVIDLDPQAN
                     LTRCFDMGNTENIKTIGHLLMVELEEEESYLVEGYTKSYDEIDIIPSSIFLSAVETQM
                     RAETGSERILSEIIRRVKENYDYILIDTSPSLSVLTINALCASDSVLIVADTQLFAVV
                     GINELLKTVQKIKKRVNPKLKVQGILLTMCENRTNLSKTLMEQVEEMFQKKIKVFQTK
                     IPKTVKVGEAIYSGQSIK"
BASE COUNT         4753 a         3034 c         3939 g         4938 t
ORIGIN      
        1 ctttcaataa ttattcgttc aactttttgg gggcagtaca ccttggggtg tttttttgtt
       61 gtaggagatt gattggttga tagaaggcag gtttatattt attgaagtga caaggtctgg
      121 aaaaaaatta tccaaaatac tggtttaagt ctactttaat attcgtcaaa tctatgctat
      181 aatgggtcat atcgccatta aggagaacga aatcatgcaa ttagtacgtg aaaaagaatt
      241 tgtcaatcag taccattatg acgccagaaa tttagaatgg gaaaaagaaa atggaacacc
      301 ggaaacaaac tttgaagtaa cctttcagtt gattaataaa gatgtggaaa ataaagagac
      361 ggctattgtt tctgttttac aatttgtcat tgtcaaggaa gagtttgtga ttagtggtgt
      421 gatttcacag atggttcgta ttttaggacg cttggtggat aagcctagtg aatttacaca
      481 agaggaggtc gaatccttgg ctgctccatt attagacatg gtgaagcgct tgacctacga
      541 agtgacagaa attgccttgg atcgtcctgg tattaatttg gagtttaaaa gttaatgaag
      601 ttagcaataa taactgataa tacagctcac cttccagagc agttagcgga gcatgccgat
      661 atttttgtat tagacatacc tgtaatcata gatggtcaaa gctatgtcga aggacaaaac
      721 ctgaccattg aagcctttta ccaaagcatg agagaatctc aagagctgcc aaaaaccagt
      781 cagcccagcc tctctgaatt agatgattta ctagggcgtc tgtcaactga gcactatact
      841 catgtgattg gcttgttctt ggctagtggt atttcaggat tttggcaaaa tattcaattt
      901 ctcatcgagg agcaccctga gttgaccatt gcttttccag atagtaaaat cacctcagca
      961 ccattaggca gcatggttag aaatgcttta gagtggtctc agcaaggctt gagctttgca
     1021 gagattatgg ataagctaga agagcaaatc gctggaacca cagcctttat catggttgat
     1081 gatttgaatc atttggtcaa gggaggacgc ttatcaaacg gttctgcttt gctgggaaat
     1141 ttgctcagca tcaagccaat tcttcgcttt gatagtgaag gaaagattgt cgtctatgaa
     1201 aaggttagaa cggaaaaaaa ggccatgaag cgcttggttg atatcttaaa ggaattgaca
     1261 gctagtggtc agtacgaggt atcaattatc catgctagag cgcaggataa ggctgatatc
     1321 ttaaagcagc tcttgttgga taatggctat acctgccctg ttgaggaggt tcattttggt
     1381 gcagtgattg cagcccatct tggagaagga gctgttgcct ttggcataac gcctcttgtc
     1441 taaagaggct tgcccatgac caatctgagc ttgatatgac agcctttaac gggaagcata
     1501 tgacaaggct ctaggagctt ttaggtggta gattaaaaca tgataacatt aatgacaatg
     1561 ccttctgaat ttcagaaggc tttaccaata gtgaaaaaaa tcaagcaggc tggctttgag
     1621 gcctattttg ttggtggaag tgtgagggat agcttattaa acaggcctat tcatgatgtt
     1681 gatatagctg ctagctgcta tccagaggag acaaaggcta ttttcttaag aacaattgat
     1741 gttgggattg agcatggcac agtgcttgtt ttagaaaatg gcagtgaata tgagatcaca
     1801 acgtttcgaa ctgaggacgt ttatgtggat tataggcgcc ctagtcaggt atcctttgtt
     1861 cggtccttgg aagaggattt aaaacgaagg gattttactg tcaatgctct tgccttagat
     1921 gaggacggac aggttattga tatctttaat ggcttagagg acctaaagca taagcttcta
     1981 agagctgttg gaaggcctca ggagcgcttt gaggaggatg ccctgcggat tatgcgaggc
     2041 tttcggtttg ctgccagctt agattttgat attgaggctg agacctttga agcaatgaaa
     2101 agccatgctc ccttgctgga gaagatttct attgagcgct cttttattga gcttgataag
     2161 cttttaatgg ccccaaaatg gcgtaaaggt atcttagcta tggtggcatg tcaggccttt
     2221 aactatttgc caggcttagt gggcaaggaa gaagccctgc aaaagtacct gaaaacctta
     2281 gcagcggatt atgtgtttca ggacaatcat caggcttggg cctatttgct ggttatgctg
     2341 gagcttgatc agcctaaagc ctttttaaag gcttggaaaa cctctaatga ttttcagcgt
     2401 agggttacga tgatggcctc tctttatcag attcgccaag aaagacagct agaaaaatgg
     2461 gatatttact cgtttggcaa ggacttggct ttactcgttg acgatttacg acaggcacag
     2521 ggcttggtca gtgaggccaa gcgtgttgag agcttgtatc aggagctgac gatccatgat
     2581 aagcatgata ttgtggtcaa tggctcttat ctgattcgtg agcttggaat gaagccagga
     2641 ccacagctgg gaatgctttt aaatcagatt gagcaggcca ttgtagaggg gcgtctcgtc
     2701 aatcaaagag aacacattga ggcttttgtt agaagggaac tactaaatga gtgattttat
     2761 cgttgaacat ctgacgaagt ctgttggaga taagaccgtt tttcaggata tttcctttat
     2821 tattcatgct ggtgatcgca ttggcattat tggtgtcaat gggacaggaa aaacaacctt
     2881 gcttgatgtt atttctgaaa aagtgggctt tgatggtgac cgctcacctt tttcaaaggc
     2941 aaatgactat cgtatatctt atttaacaca ggagccggac tttgatgatg atcagtctgt
     3001 tttagatact gttctgtccc tagaattaaa ggaaatgcag ctgattcgcc aatatgagct
     3061 gttgatggct gactattcag atagcaatca ggaaaagcta gcagaggtga tgactgagat
     3121 ggatcgatta gatgtttggt cgatcgaaag tgaggttaag acggtcttat caaagcttgg
     3181 tattgtcaat ctggatcaga gagtgggtga cctgtccggt ggtatgagac gtcgggtaca
     3241 gctggctcag gtcttgcttg gagccagtga tttgttgctg ctagatgagc cgaccaatca
     3301 tttggatatt gataccatcg cttggttaag tcattactta aggacctcta aaaggactgt
     3361 tctatttatt acacatgatc gctatttttt ggatagtata gccacacgta tctttgaatt
     3421 ggataaggct catgtgactg aatatcaggg caattaccag gattatgtgc gtctgaaggc
     3481 tgagcaagac gagcgcgaag cagctcattt gcataagaaa aagcagctct ataaacagga
     3541 gctggcttgg atgaggacac agccacaggc gcgtgcgacc aagcagcagg ccagaattaa
     3601 ccgctttgaa cagttaaaaa aggaccttca tcaggaaagg cctatagatc aattagatat
     3661 ggcctttgaa gccagtcgta ttggcaagaa ggtcattaat ttcaaggagg tttcctttgc
     3721 ttatggtgat caggccatta ttgagcattt taacctgatc attcaaaata aggaccgtat
     3781 cggcattgtt ggagctaacg gtgctggaaa gaccaccctg cttagcttga tgactggtga
     3841 cttaaaacca acagctggtc agctagagat tggcgagacg atccgtattg gttatttttc
     3901 acagcaaatc aaggatatgg acggcagcaa gcgcgtgatt agctatttgc aggaggtggc
     3961 agatgaggtc aagaccagtg ttggcaccac tagcatcagt gagcttttgg agcaatttct
     4021 ttttccgcgt tctagtcatg gctccttaat cgctaagcta tcaggcgggg agaaaaaaga
     4081 ctgtatttgc taaagctctt gatcgaaaag cccaacgtcc tgctgctgga tgagccgacc
     4141 aatgatttgg atattgcaac cttgacagtg ttggagcatt ttttagctca atttgctggt
     4201 ccggtcatta cagtgagtca tgatcggtat ttcttggata aggttgcaac aaaagtattg
     4261 gcttttgagc atggagctat cagagaatac tatggtaact atagcgacta tttagatgaa
     4321 aaggcttttg aagcagaggt catagagcct gctgtcagtg agcaaaaagc tggcactgac
     4381 catcaggtca cctctaaaaa gagaatgtcc tatcttgaga aaaaggaatg ggcagctatt
     4441 gaagaaaagc tagctgctat cgagcaacaa atagctacta ttgaggagca aatgctcaga
     4501 gcggcaagtg attacgacca attggcacaa tatcaaaagg agctggatca gcggaatctt
     4561 gagctgcttg aagcctatga gcgctttgat tacctaagcg aattagaaga ataattaatt
     4621 atgtgtcaat ttcatatttt tgtgttaaac tagttataga caaaaagaag tgctagcttg
     4681 cgcttctttt catatcacta ttatttggga ggaaatgaat ggctttaatt tggtcctatt
     4741 taaaaacaag acctaaatgg atttgtttcg atattgtggg tggcttgtta tttgttctgg
     4801 tcaatctggg gctaccaaca atattggctc gtatgattga tcaaggcgtt atgcagcagg
     4861 atcaaagggc tctttatttt tgggctctga tgatgtttat tatcgtactt ttaggtgtca
     4921 ttggacgggt gattttatcc tatgcttcgg gtaagctaac caccaacatg atcaaggatt
     4981 tacgtaatga catgtatagc tgcttgcagg attattcgca ttcggaatat gaaaaaattg
     5041 gcatagcctc cctggttact cggataacaa atgatgcctt tgttttgatg caatttgctg
     5101 aaatgtcctt gaggctgggt gtcgtaactc ctttgatgat gatcttttca gtggtgatga
     5161 tctttttaac cagtccatca ttggcttgga ttgtggctgt tgccatgcct tttttagtta
     5221 ttgtggtgct ttatgttgcg ataaagacaa gacccttatc agaaaagcag caggagagcc
     5281 ttgatcgtat taaccaattg gtgcgtgaaa acctgacagg tctgagagtt attcgagcct
     5341 ttgcaagaga agactttcaa gaagagcgct tcaataagcg caatgatcac tattctggaa
     5401 tctcaaagcg actatttacc ttgacaggct taacagagcc cttatttgtg caaattatca
     5461 ttgctatgat tgtggggatc gtctggtttg ccttggatcc cttggcaagg gggcagttta
     5521 agattggtga tttggtggcc tttatcgaat atagctttca tgctcttttt tcatttttaa
     5581 tgtttgccaa cctctttacc atgtacccta aaacagcagt gtcaagcaag cgtatcaagg
     5641 aagtgctgga tatgccgatt tcgattccta aaaatgaaga tggtataaca gcgttcacaa
     5701 cacgtggtta tctagaattt gataacgtga cctttgccta tccgggtgaa acggaaagtc
     5761 cagttttaca taacatctca tttaagacta ggcctggaga gaccattgct tttatcggct
     5821 cgacaggttc aggaaaatca tctttggtta atctgatccc acgattttat gacgtgacct
     5881 tagggagaat cttggttgat ggcattgatg tcagggatta tcaattaaaa gcgctgcgtt
     5941 ctaaaatcgg ctttattcct caaaaagccc tgctatttac aggaaccatt gaggaaaacc
     6001 taaaatatgg taagtcagat gccagccaca gtgagcttga gcaggcaaca gaggtttccc
     6061 aagcgaagga ctttattacc agtcgtgaaa agggctatca aacccatcta gctgaggccg
     6121 gcagtaatct atcaggaggg caaaagcagc gcctgtctat tgccagagca gtggtcaagc
     6181 agccagacat ctatatcttt gacgattcct tttctgccct agattacaag acagatgctg
     6241 aattacgcag acggctgaaa gaggtgacac aagatgcaac ggtcttaatt gtggctcaaa
     6301 gggtgggcac gattatggat gctgatcaaa tcattgtctt ggatcaggga gaaattgttg
     6361 gccgaggtac acatgaggaa ttgcttacaa gcaatgccat ctatcgtgaa attgccaatt
     6421 ctcagctaaa caaggaagac atgacaaaag aggaggggga ttaatgactg aaaagcatgt
     6481 gtttagaaga atttggacct accttagtgc ctataggctc tcactaataa ctgccattat
     6541 tttaaaaata gtcagtgctg tgatgagtgt cttagagccc tttgttcttg gcttggtgat
     6601 aacagagcta tctgcaaacc tattagacat agcaaaggga gtctctggtg caggcattaa
     6661 taaaacctat atcgcctttc ttttagctct ctatatcatt agggcccttg tttacgagtt
     6721 aggctcttat ggttcaaact attttatgac aagggctgtg caatcaagca tttgtgatct
     6781 tcgtcgagac ctcagtcaaa aaattaatcg tatccctgtg tcttattttg ataagcatca
     6841 gttcggcgat atgctaggcc ggtttacctc tgatgttgag acagtctcta atgccttaca
     6901 gcagtccttt ttacagattg ttaacgcctt ttttaccctt attttggtgg ttggcatggt
     6961 cttgtatatt aatgcccccc tagcctctgt tgtgattatc gctatcccgt tgatatatgc
     7021 tgcttctcga tttgttttaa aaaaatcaca gccttatttt aaagcgcagg ctaatatttt
     7081 gggagaaatg aatggctttg tgcaggaaaa tttgaccggc tttaatattt taaaactgta
     7141 tggtcgtgaa gaagcctcaa aggaggaatt tcaccagatc actgagcgat tacaagaagt
     7201 aggctttaag gccagcttta tttctgggat catgatgcca gttctgcatt ttatttcaga
     7261 ttctgtttac atgattgttg ccttaatcgc tggcttacag gtgatagcag gccgcctgac
     7321 aatcgggaac aaacatgcaa gcctttgttc agtacatttg gcaaatcagt cagcctattc
     7381 agaccataac acagctggct ggtccactgc aaagtgccaa gtcatcctta gaacgtatct
     7441 ttgcagtgct tgatgaggca gatgaattga ctattgccca agagcattta gaacatgatt
     7501 taacaggtca ggtgtccttt aatcaggttg attttagcta tacagcagac aatcctctga
     7561 ttagaaattt caatttagag gttaagcctg gtgagatggt agctatcgtt ggtccgacag
     7621 gagccggcaa gaccaccctg attaatttat taatgcggtt ttatgatgtg aatgagggct
     7681 ctatcacagt tgatggtcag gacattcgtc agttgtcacg tcaagcctat aggcgtcagt
     7741 ttggtatggt gctgcaggac gcttggctct ttgagggcag cattcaggaa aacttgcgct
     7801 ttggtcattt agaggcgact gatgaacaaa taattgaggc tgctaaggct gccaatgttg
     7861 atcatttcat taggacattg ccaggtggct atcatatggt gatgaatcag gaatctagca
     7921 atatttccct ggggcaaaag cagctgctga ccattgctcg agctctctta gcagatccaa
     7981 agctgctaat cctagatgag gccacctcgt ctgttgatac acgtttagag cttttgattc
     8041 aaaaggcgat gaagcgatta atggttggca ggactagctt tgttattgct caccgcttat
     8101 caaccattca agaggcggat aagattttag ttctaaaaga tggtcagatt atcgagcagg
     8161 ggaatcatga cagcctatta gctgctaagg gcttctatta tgagctttat catagccaat
     8221 ttaagaccag tcagtcttaa aaagcttagg gtcttggaat gaatcgttcc aaggctcttt
     8281 taatttgctt tagatcatag taaaagcttg acatcaaaat tcagaaaatt tataatattg
     8341 actatactta aaatagaatg aagaagcgag aggatatata atggtatcag caaaagacta
     8401 tgtagccagt gtttttgata aggtcaaaag ggataatccg catgagactg aatttcttca
     8461 ggcggtcaag gaggtatttg attccttgat tcctgttttt gaaaaatacc ctaattatat
     8521 tgaggaaaat ctattagagc gcttggttga gcctgagcgt gtgatttcct ttagggtgcc
     8581 ttgggttgat gaccagggca gggtccaagt taatcgtggc taccgcgtgc aattttcatc
     8641 agctatcggt ccatataagg gagggcttcg ctttcaccct tctgttaacc agtctatagt
     8701 taaatttctt ggctttgagc agattttcaa aaatgctctg actggtcagc ctattggagg
     8761 aggaaaagga ggatcaaatt ttgatcctaa aggcaaatca gacctagaaa tcatgcgctt
     8821 cacacaaagc tttatgacag agctgcaaag gcatattgga cctgaccttg atgttcctgc
     8881 tggtgatatt ggtgtagggg ctcgcgaaat tggctattta tttgggcaat ataagcgtct
     8941 taatggcttt aagaatggtg tgttgacagg aaaaggctta gcttatggtg gctctttggc
     9001 tcgcacagag gccacaggct atggtgtggt ttattttgct cagcaaatgc tggcggctaa
     9061 ggggcaggac ttggctggta aaacagctat tgtatctgga tcaggaaatg ttgccattta
     9121 cgcaacggaa aaattgcagg ccttaggtgt taaggtatta gcagtgtcgg attcctctgg
     9181 ttacgtttat gatgataagg gcattgatct tgagacccta aagcaaatca aggaagtgaa
     9241 gcgtgagcgt atcaagacct atctagagag tcacccggct gctgtgttta caccggctgg
     9301 tgagggatcc atctggacta ttaaggcaga ccttgccttt ccatgtgcga ctcaaaatga
     9361 gctacaagag gcagatgcta aagccttgat tgagcatggg gttaaagctg ttgtcgaagg
     9421 ggctaacatg ccctcaacct tagaggctat tgagcaattt cagcaggctg gggttctttt
     9481 tggacctgct aaagcagcaa atgctggcgg tgtagcagtt tctgcgctgg aaatggcaca
     9541 aaatagcgga cgtaccgcat ggacctttga agaggtggat catcgattgt atgacatcat
     9601 gaaggctatt tatcaaaaag cagccgctgc cgccaaggaa tgtggtcaag aaggcaacct
     9661 agtggtggga gctaatattg caggctttct caaagttgct caggccatgt cagcacaggg
     9721 aatcgtttaa gagctgtggc tggtatatgc tgaatatatc agtagggtta gcacattaat
     9781 cttagctcaa tgacgttaag atatacgatc ggtcatctag acaatgcatg ccgattagag
     9841 caatgaatca aggagaagct gatgatcaaa aaaatcgtga aggacacctt tttcttgcag
     9901 caaaaagcac agccagcaac gaaaaaggac ctttggattg gtcaagacct gcaggatacc
     9961 ttagcttatt atcgtgatag ctgcctgggg ctggctgcta atatgatagg ggaaaacaag
    10021 agggttatta ttattagcat gggctttgtg gatttggtga tgtttaatcc tgtattaatt
    10081 gctaagcgtg aagcgtttga ggcagaggaa tcctgcctat cactaatcgg ccaacgtaag
    10141 acaaagcgtt atcaggagat caaggttgat taccttgatg cacattggca caagaaatcc
    10201 ctgagattga caggcctgcc tgcacaaatc tgccagcatg agctggatca tctggagggc
    10261 atattgattt aaatcatgac cacccgttag tgaactgcac cccaaaagtt agacagaaaa
    10321 tctaacgaat gagggcagtc catagatggg tggtttattt gtcttgctca acaggtgcga
    10381 aacaaataaa cgtcacataa atcagaaaac cggctgtatg cttaagatac agtcggttat
    10441 tgctgttatg gctaggacga ttttattggc cttccttttt cttgaaaagg ctagtaccag
    10501 ttaaggttag tagtcctagg attgtcatgg cagcagcaga atgctggctt gttcctgttg
    10561 ctggtaaggc agcattagct tgctttttag ctgctagagg cttgatgctt gtggcaggat
    10621 tagcattttg agcaggcgta aataggtcag agacaagctc agtagcaagc accttgccct
    10681 cacgattctt aaagacgcgg ttgatgatct cgtgcttgcc ggtatgatca ctttgagtag
    10741 agccttcaag actggcagtg acataggttt tcacaccgtt aataccagca cttacagtct
    10801 ttccagctgc ttcaaggtcc ttgatgtatt cgataaagac ctcagtatca ggattaatgg
    10861 ctcctagtag cttagcgtcc ttaaagacgg agaagccatc accaccgcca tataggaagt
    10921 cgttgatgat tagggtgtat tgagctgctg gatcaatttc ttcaccatta tctttataag
    10981 cctttactac cttaaacggt gttgaaggat cgttagcctc attagctgta taagtgtatt
    11041 tgagtccaga catttgaagg aagtattttt ggtcttcatc gtattgttgg ttcaagacat
    11101 catagatttg ttggccagtc atttgaacga cctgaagaat attgccaaat ggttgaacag
    11161 cctgtgcagc tccccaggta atggtttgat cctctttgac caccaagtca gcgcgaatac
    11221 cgccattatt tgtcatggca aaatcaacat gagggaaggt ttttctacca atggttaatt
    11281 gggcagttgt tatcaaattg ccaacaggag attccttgtc ttcgttttct gttttagaaa
    11341 tcgttgaaga ggtagctgct gtaccgatct ttagctcggt aacggttttg acaatgtcat
    11401 tggcttgatc aacaatggct tgaatgtcgg cattgcctgt ttttatgcca ggagcaacgg
    11461 caatgacctt tgcttcagga gtggctacaa aatcattgag gtcagtgtct agtgttccac
    11521 gaacatctgc ataggctttc ccctgtgaaa cagcctgaac gacacgtgtt gtgccaatgg
    11581 taccgttggt gtattggtgg ttgtgaccag caaagacaat atccacacta tgctcaggat
    11641 aaagctggtt aaccttttcc ataactgctg ccatctcatc atgaactacc ccgttatcac
    11701 ttgttgctgg gatatgagct aggacaacaa tcgcattgac ctgctgctct tggagctctt
    11761 tagcatattt aacgatggtt tctgcagagt ctaggtaatc atattgttca taattttgtt
    11821 ttaggacaag gtttggaatt tctgttgtca caacaccgat aaagcccacc ttgactgact
    11881 tatcattaac tgggacttct ttgacagcat aaggcttcca gccaaaagga atcgtgttgg
    11941 tctccttgtc aacgacattt gcaatgacaa gggtttgatt tgaagcttca tgctcgtatt
    12001 gcttagtaat gtcgttgata gctgagtctt cagcaggtgc agtgcctgtc atgatacggt
    12061 tgaattcagc taagccctca tcgaattcgt gattcccaag ggttccgtat tcaaagccca
    12121 tctggttgaa taccttaacc gttggctcgt cctgtaatag tccagaatta gcaggactag
    12181 ctccgaccat atctcctggt tgaacacgaa tgcttgtccc atctgggctt gtttgcttaa
    12241 agtcagcctc tgcatcgtcc agataagcag ctaattgtgc tgcggtacca gcgttagata
    12301 cctttccttc tggcatgtag gcagagccgg ttgtgtctaa ggcaccatga aagtcattga
    12361 caccaagaaa ttgcacgtct acctgatcgg cctgcacgcc ggttactagc atagaaactc
    12421 cggcaaagac accaagaaca ctacttttta aaacaaaatg ctttttcata aacgctccta
    12481 aaagtttaaa gtattgtcac aagttaagtg tactattatt taaatgagaa ttcaacaaaa
    12541 attaataaaa aagctaacaa aaattcaacg atagcgtttg ctaatcactg aaaacgttta
    12601 aaatgcaaac attggaagcg ttttttgtaa aaaaatagaa gaactatcca aaaaaggctt
    12661 tacaagccca gtattctatg ataagatgtt aggcagatta aaagaaagga gaaattaata
    12721 atgatccgtt tcattcaact atttaaccat tattacgata gtctcctttc taaccaaaac
    12781 agttagtttc ttttagtttc actaaataga aatagtagag cccgcggtag gaaggatatc
    12841 ttattgcggg ctttttgtgt gcaaaaatcc tattttaaga cagcttgaaa taggttagtt
    12901 cagaaatgga ggatatgatg ctgaccttaa ttgttcaaca tattaagcaa aagaaatgga
    12961 tttatatcct tattgcaatg actttagtga tatatgatgc ctcacttgtg ataccaacaa
    13021 gggttattca agacttggtt gatttgatgt caaggcatca gctaagctca ggggcattgg
    13081 tgaggcatgt tatcattctt ttggctacgg cagtagtgtc ttatggggtt gcttatttgt
    13141 ggcatcttca tttatttcag gaggcagttc attttaagtt tgatattcag cagcgtgcct
    13201 ttcgaaagct tgtttttatg agaacgcctt tttatgagaa atttcgctca ggtgacatga
    13261 tcacgcgttt ttcaacagat gtcgaagcac ttatggacct tatcggctat ggcttgatga
    13321 ttatcctata tgctggtggt atgattgctt ttattattcc gaccatgttt ttgatttctt
    13381 ggaaaatgac cttgatagga atagtaccga ttttgcttat gatggtgatg atctatggtg
    13441 tgacgaaaaa gcaagagcat ttggttgaag aggcgcgtga ggcgatttca agccttagtg
    13501 atgaggtact agaaaccgtt gagggcatta gagtgatgcg tgcttacagt aaaaaagatt
    13561 atttggcact tcattttgct caaaagactc agaatttggc agataaatgg aatcaggtgg
    13621 ccaagtatcg tgccttgtac tttcctcttt acagcgtcat gattgccatt agtacagtaa
    13681 tcattttaat ggtaggccta cagctcatag caagctcaga ggtaacactt ggtcaagtca
    13741 ttgcgctgca gctttatctg gtgtctttgg tggagccctt tggcatgctg tcagacttta
    13801 ttttggttta tcagacagga aagacctctt ttggtaagat taatgaactc atcgaaacaa
    13861 gtgatgatat ggagcctgat ggccagcttg agttagagag ctttgatcag attgctttta
    13921 tagactatag ctttacctat gccaatagtt ctaggcctag cttagaaaag atcaatttaa
    13981 ccctgaaaaa gggacaaacc ttagggattg ttggtaaaac aggctctggt aaaacaaccc
    14041 ttgtcaggca gtttttgaga caataccctc ttgggcaggg gcagctgatg attaatcatc
    14101 gtagtgtctt ggattataag cgtcaatcac ttgagcgtca aattggctat gtgccacagg
    14161 agcatatcct gttttcaaaa acggttgctc aaaacattgc gatggggaaa aaggcagcta
    14221 caactgagga aatcttggag gcgattgaaa ctgcggcctt tacgcgtgat gttcaaggaa
    14281 tggcaaaggg cttggatact gagattggag agcgtggtct gtctatttca ggaggtcaaa
    14341 agcagcgtat ttcgattgcc agagcctttt tgtcccagcc agatttgctg attttagatg
    14401 attccctgtc ggcagttgat gctagaacag agactgatat tattcgacac attcaagacg
    14461 aaagaaaggg aaagacaaca cttattgtta gccatcgctt gtctgcgatt cagcatgccg
    14521 attgggttat tgttctggat caggggcaga tagtagagga aggtcagccc caacaacttt
    14581 tagctcagaa gggctggtat tatgaacagt accagcgtca gcaggctcag gaggtttaag
    14641 atgaccctat ttataaaatt aataaaagaa attaaagctg tgaccttggc tttttccctg
    14701 gcaataggct ttttgctagt ggcaacagct ggaggtcaga tggctccctt attgttgcaa
    14761 caaacgattg atcattactt gactccgata gctagaggaa aagaggtacc gattgaaggc
    14821 tttcagcgct tgctcctgct gtatttgctg ttaattgtga taacagcagt tttgcgttat
    14881 atctcttatc gaatgctggt ttattcctct aataggatcg ttgctaatct tcgtaatcga
    14941 gcctttgatg tcatgcagag gctgccgata gcttattttg atcatcagcc tgcaggaaag
    15001 attgcaacta ggattgttaa tgatactgaa accctgaaga atcaatttta tgataacctt
    15061 ttgtctcaaa ttattgtcag tctttcacaa attattttta tttatgtggt gatgatttac
    15121 cttgatgtga agtcaggctt gctgttgctg cttattatgc cactctttta tggcatgcaa
    15181 tggctgtata aaagcttgac tgaccagcca atgaaggatt tttatcaggc taggagcgct
    15241 gtcaacacac aagtcaacga aaccatgaat ggtgtttcta ttattcagct ttatcatcaa
    15301 gaggatacga tcttagagga atttgaagag cagatccacc agatgaaaac agctgatgat
    15361 aggattattt ttgcagagtc agttgcttca tggaccctga cggaattggt aaagtatggc
    15421 atgattgccg ctattttggc tgttattggt taccagttct tgcaggggag atcaggcatc
    15481 acagttggta agctctttat ttacgtcaat tatttgctgc gcttgtttga tttattaagt
    15541 atgctggtta ggcagctacc taatattcag cgctcaacag cgacaggaac gcgcctaatg
    15601 aagctgcttg aggcgcagac agagccggat aaagcacgag caattgagct aacagatggt
    15661 actgtggatt ttaccaaggt gtattttgct tacgaaaatg gcaagacagt tttatctgat
    15721 attaccattc atgctgataa aggggagacg gttgccctag tagggcatac tggctctggg
    15781 gacaatgcta taatgatgat agtacaataa atccaagtaa aatcaatggt taaaggcttc
    15841 cgcaaaactt ttaaacttga tgatggattg aggctatcat ctttttttat atctaaaatt
    15901 atataaaagt atagcataaa atgaaatctc tgtatagaga agaaggaggg actttatggc
    15961 agaagtgata accatagcca atcgaaaagg cggagttgga aaaacaacta caactctaaa
    16021 ccttgcctat tcactaaaag aactggggaa aaaagtatta gtcattgacc ttgatccaca
    16081 agctaatctt acaagatgtt ttgatatggg aaatacagaa aatataaaaa ccatagggca
    16141 tttgttaatg gtagaactgg aggaagaaga aagctatttg gtagagggct ataccaaatc
    16201 ttatgatgag atagatatta tcccctcaag cattttctta tccgccgttg aaacacaaat
    16261 gagagcagaa acaggaagtg aacgtatatt atcggaaatt attaggaggg taaaagagaa
    16321 ttatgactat attctcatag atacatcacc atcacttagt gttttgacta taaatgctct
    16381 ttgtgcctca gacagtgtcc ttatagtagc ggatacacag ctgttcgcag ttgttggaat
    16441 caatgaactt ttaaaaactg ttcaaaaaat aaaaaagaga gtgaatccga aactgaaagt
    16501 gcaggggatt ttactaacca tgtgtgagaa tagaaccaat ctgtccaaaa cactgatgga
    16561 gcaagtagaa gaaatgttcc aaaagaaaat caaggtcttt caaaccaaaa ttccgaaaac
    16621 agttaaagtt ggggaagcca tctatagcgg gcaaagcata aaaa
//
